1	mitochondrion inheritance	P	The distribution of mitochondria, including the mitochondrial genome, into daughter cells after mitosis or meiosis, mediated by interactions between mitochondria and the cytoskeleton.
2	mitochondrial genome maintenance	P	The maintenance of the structure and integrity of the mitochondrial genome; includes replication and segregation of the mitochondrial chromosome.
3	reproduction	P	The production of new individuals that contain some portion of genetic material inherited from one or more parent organisms.
6	high-affinity zinc uptake transmembrane transporter activity	F	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Zn2+(out) = Zn2+(in), probably powered by proton motive force. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.
7	low-affinity zinc ion transmembrane transporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Zn2+ = Zn2+, probably powered by proton motive force. In low-affinity transport the transporter is able to bind the solute only if it is present at very high concentrations.
9	alpha-1,6-mannosyltransferase activity	F	Catalysis of the transfer of a mannose residue to an oligosaccharide, forming an alpha-(1->6) linkage.
10	trans-hexaprenyltranstransferase activity	F	Catalysis of the reaction: all-trans-hexaprenyl diphosphate + isopentenyl diphosphate = all-trans-heptaprenyl diphosphate + diphosphate.
11	vacuole inheritance	P	The distribution of vacuoles into daughter cells after mitosis or meiosis, mediated by interactions between vacuoles and the cytoskeleton.
12	single strand break repair	P	The repair of single strand breaks in DNA. Repair of such breaks is mediated by the same enzyme systems as are used in base excision repair.
14	single-stranded DNA endodeoxyribonuclease activity	F	Catalysis of the hydrolysis of ester linkages within a single-stranded deoxyribonucleic acid molecule by creating internal breaks.
15	phosphopyruvate hydratase complex	C	A multimeric enzyme complex, usually a dimer or an octamer, that catalyzes the conversion of 2-phospho-D-glycerate to phosphoenolpyruvate and water.
16	lactase activity	F	Catalysis of the reaction: lactose + H2O = D-glucose + D-galactose.
17	alpha-glucoside transport	P	The directed movement of alpha-glucosides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Alpha-glucosides are glycosides in which the sugar group is a glucose residue, and the anomeric carbon of the bond is in an alpha configuration.
18	regulation of DNA recombination	P	Any process that modulates the frequency, rate or extent of DNA recombination, a DNA metabolic process in which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents.
19	regulation of mitotic recombination	P	Any process that modulates the frequency, rate or extent of DNA recombination during mitosis.
22	mitotic spindle elongation	P	The cell cycle process in which the distance is lengthened between poles of the mitotic spindle. Mitotic spindle elongation begins during mitotic prophase and ends during mitotic anaphase B.
23	maltose metabolic process	P	The chemical reactions and pathways involving the disaccharide maltose (4-O-alpha-D-glucopyranosyl-D-glucopyranose), an intermediate in the catabolism of glycogen and starch.
24	maltose biosynthetic process	P	The chemical reactions and pathways resulting in the formation of the disaccharide maltose (4-O-alpha-D-glucopyranosyl-D-glucopyranose).
25	maltose catabolic process	P	The chemical reactions and pathways resulting in the breakdown of the disaccharide maltose (4-O-alpha-D-glucopyranosyl-D-glucopyranose).
26	alpha-1,2-mannosyltransferase activity	F	Catalysis of the transfer of a mannose residue to an oligosaccharide, forming an alpha-(1->2) linkage.
27	ribosomal large subunit assembly	P	The aggregation, arrangement and bonding together of constituent RNAs and proteins to form the large ribosomal subunit.
28	ribosomal small subunit assembly	P	The aggregation, arrangement and bonding together of constituent RNAs and proteins to form the small ribosomal subunit.
30	mannosyltransferase activity	F	Catalysis of the transfer of a mannosyl group to an acceptor molecule, typically another carbohydrate or a lipid.
31	mannosylphosphate transferase activity	F	Catalysis of the transfer of a mannosylphosphate group from one compound to another.
32	cell wall mannoprotein biosynthetic process	P	The chemical reactions and pathways resulting in the formation of cell wall mannoproteins, any cell wall protein that contains covalently bound mannose residues.
33	alpha-1,3-mannosyltransferase activity	F	Catalysis of the transfer of a mannose residue to an oligosaccharide, forming an alpha-(1->3) linkage.
34	adenine deaminase activity	F	Catalysis of the reaction: adenine + H2O = hypoxanthine + NH3.
35	acyl binding	F	Interacting selectively and non-covalently with an acyl group, any group formally derived by removal of the hydroxyl group from the acid function of a carboxylic acid.
36	ACP phosphopantetheine attachment site binding involved in fatty acid biosynthetic process	F	Interacting selectively and non-covalently with the attachment site of the phosphopantetheine prosthetic group of an acyl carrier protein (ACP) as part of the process of fatty acid biosynthesis.
38	very long-chain fatty acid metabolic process	P	The chemical reactions and pathways involving a fatty acid which has a chain length greater than C22.
40	low-affinity iron ion transmembrane transport	P	A process in which an iron ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore. In low-affinity transport the transporter is able to bind the solute only if it is only present at very low concentrations.
41	transition metal ion transport	P	The directed movement of transition metal ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A transition metal is an element whose atom has an incomplete d-subshell of extranuclear electrons, or which gives rise to a cation or cations with an incomplete d-subshell. Transition metals often have more than one valency state. Biologically relevant transition metals include vanadium, manganese, iron, copper, cobalt, nickel, molybdenum and silver.
42	protein targeting to Golgi	P	The process of directing proteins towards the Golgi; usually uses signals contained within the protein.
45	autophagosome assembly	P	The formation of a double membrane-bounded structure, the autophagosome, that occurs when a specialized membrane sac, called the isolation membrane, starts to enclose a portion of the cytoplasm.
48	peptidyltransferase activity	F	Catalysis of the reaction: peptidyl-tRNA(1) + aminoacyl-tRNA(2) = tRNA(1) + peptidylaminoacyl-tRNA(2).
49	tRNA binding	F	Interacting selectively and non-covalently with transfer RNA.
50	urea cycle	P	The sequence of reactions by which arginine is synthesized from ornithine, then cleaved to yield urea and regenerate ornithine. The overall reaction equation is NH3 + CO2 + aspartate + 3 ATP + 2 H2O = urea + fumarate + 2 ADP + 2 phosphate + AMP + diphosphate.
52	citrulline metabolic process	P	The chemical reactions and pathways involving citrulline, N5-carbamoyl-L-ornithine, an alpha amino acid not found in proteins.
53	argininosuccinate metabolic process	P	The chemical reactions and pathways involving argininosuccinate, 2-(N(omega)-arginino)succinate, an intermediate in the ornithine-urea cycle, where it is synthesized from citrulline and aspartate.
54	ribosomal subunit export from nucleus	P	The directed movement of a ribosomal subunit from the nucleus into the cytoplasm.
55	ribosomal large subunit export from nucleus	P	The directed movement of a ribosomal large subunit from the nucleus into the cytoplasm.
56	ribosomal small subunit export from nucleus	P	The directed movement of a ribosomal small subunit from the nucleus into the cytoplasm.
59	protein import into nucleus, docking	P	A protein complex assembly process that contributes to protein import into the nucleus, and that results in the association of a cargo protein, a carrier protein such as an importin alpha/beta heterodimer, and a nucleoporin located at the periphery of the nuclear pore complex.
60	protein import into nucleus, translocation	P	A protein transport process that contributes to protein import into the nucleus, and that results in the vectorial transfer of a cargo-carrier protein complex through the nuclear pore complex from the cytoplasmic side to the nucleoplasmic side of the nuclear envelope.
61	protein import into nucleus, substrate release	P	A protein complex disassembly process that contributes to protein import into the nucleus, and that results in the dissociation of the cargo protein and the carrier (such as an importin alpha/beta heterodimer) from each other and from the nuclear pore complex.
62	fatty-acyl-CoA binding	F	Interacting selectively and non-covalently with acyl-CoA, any derivative of coenzyme A in which the sulfhydryl group is in thiolester linkage with a fatty acyl group.
64	L-ornithine transmembrane transporter activity	F	Enables the transfer of L-ornithine from one side of a membrane to the other. L-ornithine is 2,5-diaminopentanoic acid.
66	mitochondrial ornithine transport	P	The directed movement of ornithine, 2,5-diaminopentanoic acid, into, out of or within a mitochondrion.
70	mitotic sister chromatid segregation	P	The cell cycle process in which replicated homologous chromosomes are organized and then physically separated and apportioned to two sets during the mitotic cell cycle. Each replicated chromosome, composed of two sister chromatids, aligns at the cell equator, paired with its homologous partner. One homolog of each morphologic type goes into each of the resulting chromosome sets.
73	spindle pole body separation	P	A largely uncharacterized process involving the release of duplicated spindle pole bodies (SPBs) and their migration away from each other within the nuclear membrane. Duplicated SPBs are connected by a bridge structure that may be severed in order to release the SPBs from one another. Following liberation, SPBs diffuse through the nuclear membrane until they are across from each other. SPB separation must take place in order for a bipolar mitotic spindle to assemble.
75	cell cycle checkpoint	P	A cell cycle process that controls cell cycle progression by monitoring the integrity of specific cell cycle events. A cell cycle checkpoint begins with detection of deficiencies or defects and ends with signal transduction.
76	DNA replication checkpoint	P	A cell cycle checkpoint that prevents the initiation of nuclear division until DNA replication is complete, thereby ensuring that progeny inherit a full complement of the genome.
77	DNA damage checkpoint	P	A cell cycle checkpoint that regulates progression through the cell cycle in response to DNA damage. A DNA damage checkpoint may blocks cell cycle progression (in G1, G2 or metaphase) or slow the rate at which S phase proceeds.
79	regulation of cyclin-dependent protein serine/threonine kinase activity	P	Any process that modulates the frequency, rate or extent of cyclin-dependent protein serine/threonine kinase activity.
80	mitotic G1 phase	P	The cell cycle 'gap' phase which is the interval between the completion of DNA segregation by mitosis and the beginning of DNA synthesis.
82	G1/S transition of mitotic cell cycle	P	The mitotic cell cycle transition by which a cell in G1 commits to S phase. The process begins with the build up of G1 cyclin-dependent kinase (G1 CDK), resulting in the activation of transcription of G1 cyclins. The process ends with the positive feedback of the G1 cyclins on the G1 CDK which commits the cell to S phase, in which DNA replication is initiated.
83	regulation of transcription involved in G1/S transition of mitotic cell cycle	P	Any process that regulates transcription such that the target genes are involved in the transition between G1 and S phase of the mitotic cell cycle.
84	mitotic S phase	P	The cell cycle phase, following G1, during which DNA synthesis takes place as part of a mitotic cell cycle.
85	mitotic G2 phase	P	The cell cycle 'gap' phase which is the interval between the completion of DNA synthesis and the beginning of DNA segregation by mitosis.
86	G2/M transition of mitotic cell cycle	P	The mitotic cell cycle transition by which a cell in G2 commits to M phase. The process begins when the kinase activity of M cyclin/CDK complex reaches a threshold high enough for the cell cycle to proceed. This is accomplished by activating a positive feedback loop that results in the accumulation of unphosphorylated and active M cyclin/CDK complex.
87	mitotic M phase	P	A cell cycle phase during which nuclear division occurs, and which is comprises the phases: prophase, metaphase, anaphase and telophase and occurs as part of a mitotic cell cycle.
88	mitotic prophase	P	The cell cycle phase which is the first stage of M phase of mitosis and during which chromosomes condense and the two daughter centrioles and their asters migrate toward the poles of the cell.
89	mitotic metaphase	P	The cell cycle phase, following prophase, during which chromosomes become aligned on the equatorial plate of the cell as part of a mitotic cell cycle.
90	mitotic anaphase	P	The cell cycle phase during which chromosomes separate and migrate towards the poles of the spindle the as part of a mitotic cell cycle.
91	mitotic anaphase A	P	The cell cycle phase during which the kinetochore microtubules shorten as chromosomes move toward the spindle poles as part of mitosis.
92	mitotic anaphase B	P	The cell cycle phase during which the polar microtubules elongate and the two poles of the spindle move farther apart as part of mitosis.
93	mitotic telophase	P	The cell cycle phase which follows anaphase during M phase of mitosis and during which the chromosomes arrive at the poles of the cell and the division of the cytoplasm starts.
95	S-adenosyl-L-methionine transmembrane transporter activity	F	Enables the transfer of S-adenosylmethionine from one side of a membrane to the other. S-adenosylmethionine is S-(5'-adenosyl)-L-methionine, an important intermediate in one-carbon metabolism.
96	sulfur amino acid metabolic process	P	The chemical reactions and pathways involving amino acids containing sulfur, comprising cysteine, homocysteine, methionine and selenocysteine.
97	sulfur amino acid biosynthetic process	P	The chemical reactions and pathways resulting in the formation of amino acids containing sulfur, comprising cysteine, methionine and selenocysteine.
98	sulfur amino acid catabolic process	P	The chemical reactions and pathways resulting in the breakdown of amino acids containing sulfur, comprising cysteine, methionine and selenocysteine.
99	sulfur amino acid transmembrane transporter activity	F	Enables the transfer of sulfur amino acids from one side of a membrane to the other. Sulphur amino acids contain sulfur in the form of cystine, methionine or their derivatives.
100	S-methylmethionine transmembrane transporter activity	F	Catalysis of the transfer of S-methylmethionine from one side of a membrane to the other.
101	sulfur amino acid transport	P	The directed movement of amino acids containing sulfur (cystine, methionine and their derivatives) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
102	L-methionine secondary active transmembrane transporter activity	F	Catalysis of the transfer of L-methionine from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Chemiosmotic sources of energy include uniport, symport or antiport.
103	sulfate assimilation	P	The pathways by which inorganic sulfate is processed and incorporated into sulfated compounds.
104	succinate dehydrogenase activity	F	Catalysis of the reaction: succinate + acceptor = fumarate + reduced acceptor.
105	histidine biosynthetic process	P	The chemical reactions and pathways resulting in the formation of histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid.
107	imidazoleglycerol-phosphate synthase activity	F	Catalysis of the reaction: phosphoribulosylformimino-AICAR-P + L-glutamine = D-erythro-imidazole-glycerol-phosphate + aminoimidazole carboxamide ribonucleotide + L-glutamate + 2 H(+).
109	nucleotide-excision repair complex	C	Any complex formed of proteins that act in nucleotide-excision repair.
110	nucleotide-excision repair factor 1 complex	C	One of several protein complexes involved in nucleotide-excision repair; possesses DNA damage recognition and endodeoxynuclease activities. In S. cerevisiae, it is composed of Rad1p, Rad10p, and Rad14p; in human the subunits are ERCC4/XPF, ERCC1 and XPA, respectively.
111	nucleotide-excision repair factor 2 complex	C	One of several protein complexes involved in nucleotide-excision repair; possesses damaged DNA binding activity. In S. cerevisiae, it is composed of Rad4p and Rad23p.
112	nucleotide-excision repair factor 3 complex	C	One of several protein complexes involved in nucleotide-excision repair; possesses endodeoxynuclease and DNA helicase activities. In S. cerevisiae, it is composed of Rad2p and the core TFIIH-Ssl2p complex (core TFIIH is composed of Rad3p, Tfb1p, Tfb2p, Ssl1p, Tfb4p and Tfb5p. Note that Ssl2p is also called Rad25p).
113	nucleotide-excision repair factor 4 complex	C	One of several protein complexes involved in nucleotide-excision repair; possesses DNA damage recognition and DNA-dependent ATPase activities. In S. cerevisiae, it is composed of Rad7p and Rad16p.
117	regulation of transcription involved in G2/M transition of mitotic cell cycle	P	Any process that regulates transcription such that the target genes are transcribed as part of the G2/M transition of the mitotic cell cycle.
118	histone deacetylase complex	C	A protein complex that possesses histone deacetylase activity.
120	RNA polymerase I transcription factor complex	C	A transcription factor complex that acts at promoters of genes transcribed by RNA polymerase I.
121	glycerol-1-phosphatase activity	F	Catalysis of the reaction: glycerol-1-phosphate + H2O = glycerol + phosphate.
122	negative regulation of transcription from RNA polymerase II promoter	P	Any process that stops, prevents, or reduces the frequency, rate or extent of transcription from an RNA polymerase II promoter.
123	histone acetyltransferase complex	C	A protein complex that possesses histone acetyltransferase activity.
124	SAGA complex	C	A SAGA-type histone acetyltransferase complex that contains Spt8 (in budding yeast) or a homolog thereof; additional polypeptides include Spt group, consisting of Spt7, Spt3, and Spt20/Ada5, which interact with the TATA-binding protein (TBP); the Ada group, consisting of Ada1, Ada2, Ada3, Ada4/Gcn5, and Ada5/Spt20, which is functionally linked to the nucleosomal HAT activity; Tra1, an ATM/PI-3 kinase-related protein that targets DNA-bound activators for recruitment to promoters; the TBP-associated factor (TAF) proteins, consisting of Taf5, Taf6, Taf9, Taf10, and Taf12, which mediate nucleosomal HAT activity and are thought to help recruit the basal transcription machinery.
125	PCAF complex	C	A large multiprotein complex that possesses histone acetyltransferase activity and is involved in regulation of transcription. The composition is similar to that of the SAGA complex, but includes fewer Spt and Ada proteins, and more TAFs.
126	transcription factor TFIIIB complex	C	A transcription factor complex that is involved in regulating transcription from RNA polymerase III (Pol III) promoters. TFIIIB contains the TATA-binding protein (TBP) and two Pol III-specific proteins, B'' and BRF.
127	transcription factor TFIIIC complex	C	A heterotrimeric transcription factor complex that is involved in regulating transcription from RNA polymerase III (Pol III) promoters. TFIIIC contains three conserved subunits that associate with the proximal Pol III promoter element, and additional subunits that associate with sequence elements downstream of the promoter and are more diverged among species. It also functions as a boundary element to partition genome content into distinct domains outside Pol III promoter regions.
128	flocculation	P	The reversible, non-sexual aggregation of single-celled organisms in suspension to form aggregates of many cells known as flocs.
131	incipient cellular bud site	C	The portion of the budding yeast plasma membrane where a daughter cell will emerge. The yeast marks this spot with bud-site selection proteins before bud emergence occurs. Actin is polarized to this spot just prior to and during bud emergence.
132	establishment of mitotic spindle orientation	P	A cell cycle process that sets the alignment of mitotic spindle relative to other cellular structures.
133	polarisome	C	Protein complex that plays a role in determining cell polarity by directing the localized assembly of actin filaments at polarization sites; in Saccharomyces the polarisome includes Bni1p, Spa2p, Pea2p, and Bud6p.
136	alpha-1,6-mannosyltransferase complex	C	A large, multiprotein complex with alpha-(1->6)-mannosyltransferase activity, located in the cis Golgi membrane; adds mannan to N-linked glycans on proteins.
137	Golgi cis cisterna	C	The Golgi cisterna closest to the endoplasmic reticulum; the first processing compartment through which proteins pass after export from the ER.
138	Golgi trans cisterna	C	The Golgi cisterna farthest from the endoplasmic reticulum; the final processing compartment through which proteins pass before exiting the Golgi apparatus; the compartment in which N-linked protein glycosylation is completed.
139	Golgi membrane	C	The lipid bilayer surrounding any of the compartments of the Golgi apparatus.
140	acylglycerone-phosphate reductase activity	F	Catalysis of the reaction: 1-palmitoylglycerol-3-phosphate + NADP+ = palmitoylglycerone phosphate + NADPH + H(+).
142	cellular bud neck contractile ring	C	A contractile ring, i.e. a cytoskeletal structure composed of actin filaments and myosin, that forms beneath the plasma membrane at the mother-bud neck in mitotic cells that divide by budding in preparation for completing cytokinesis. An example of this structure is found in Saccharomyces cerevisiae.
144	cellular bud neck septin ring	C	A ring-shaped structure that forms at the site of cytokinesis in the bud neck of a budding cell; composed of members of the conserved family of filament forming proteins called septins as well as septin-associated proteins. In S. cerevisiae, this structure forms at the time of bud emergence and the septins show a high rate of exchange.
145	exocyst	C	A protein complex peripherally associated with the plasma membrane that determines where vesicles dock and fuse. At least eight complex components are conserved between yeast and mammals.
146	microfilament motor activity	F	Catalysis of movement along a microfilament, coupled to the hydrolysis of a nucleoside triphosphate (usually ATP).
147	actin cortical patch assembly	P	Assembly of an actin cortical patch, a discrete actin-containing structure found at the plasma membrane of fungal cells.
148	1,3-beta-D-glucan synthase complex	C	A protein complex that catalyzes the transfer of a glucose group from UDP-glucose to a (1->3)-beta-D-glucan chain.
149	SNARE binding	F	Interacting selectively and non-covalently with a SNARE (soluble N-ethylmaleimide-sensitive factor attached protein receptor) protein.
150	recombinase activity	F	Catalysis of the identification and base-pairing of homologous sequences between single-stranded DNA and double-stranded DNA.
151	ubiquitin ligase complex	C	A protein complex that includes a ubiquitin-protein ligase and enables ubiquitin protein ligase activity. The complex also contains other proteins that may confer substrate specificity on the complex.
152	nuclear ubiquitin ligase complex	C	A ubiquitin ligase complex found in the nucleus.
153	cytoplasmic ubiquitin ligase complex	C	A ubiquitin ligase complex found in the cytoplasm.
154	rRNA modification	P	The covalent alteration of one or more nucleotides within an rRNA molecule to produce an rRNA molecule with a sequence that differs from that coded genetically.
155	phosphorelay sensor kinase activity	F	Catalysis of the phosphorylation of a histidine residue in response to detection of an extracellular signal such as a chemical ligand or change in environment, to initiate a change in cell state or activity. The two-component sensor is a histidine kinase that autophosphorylates a histidine residue in its active site. The phosphate is then transferred to an aspartate residue in a downstream response regulator, to trigger a response.
156	phosphorelay response regulator activity	F	Responds to a phosphorelay sensor to initiate a change in cell state or activity. The activity of the response regulator is regulated by transfer of a phosphate from a histidine residue in the sensor, to an aspartate residue in the response regulator. Many but not all response regulators act as transcriptional regulators to elicit a response.
159	protein phosphatase type 2A complex	C	A protein complex that has protein serine/threonine phosphatase activity that is polycation-stimulated (PCS), being directly stimulated by protamine, polylysine, or histone H1; it constitutes a subclass of several enzymes activated by different histones and polylysine, and consists of catalytic, scaffolding, and regulatory subunits. The catalytic and scaffolding subunits form the core enzyme, and the holoenzyme also includes the regulatory subunit.
160	phosphorelay signal transduction system	P	A conserved series of molecular signals found in prokaryotes and eukaryotes; involves autophosphorylation of a histidine kinase and the transfer of the phosphate group to an aspartate that then acts as a phospho-donor to response regulator proteins.
161	MAPK cascade involved in osmosensory signaling pathway	P	A MAPK cascade involved in signal transduction in response to change in osmotic conditions.
162	tryptophan biosynthetic process	P	The chemical reactions and pathways resulting in the formation of tryptophan, the chiral amino acid 2-amino-3-(1H-indol-3-yl)propanoic acid; tryptophan is synthesized from chorismate via anthranilate.
164	protein phosphatase type 1 complex	C	A protein complex that possesses magnesium-dependent protein serine/threonine phosphatase (AMD phosphatase) activity, and consists of a catalytic subunit and one or more regulatory subunits that dictates the phosphatase's substrate specificity, function, and activity.
165	MAPK cascade	P	An intracellular protein kinase cascade containing at least a MAPK, a MAPKK and a MAP3K. The cascade can also contain two additional tiers: the upstream MAP4K and the downstream MAP Kinase-activated kinase (MAPKAPK). The kinases in each tier phosphorylate and activate the kinases in the downstream tier to transmit a signal within a cell.
166	nucleotide binding	F	Interacting selectively and non-covalently with a nucleotide, any compound consisting of a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose or deoxyribose.
167	activation of MAPKKK activity involved in osmosensory signaling pathway	P	Any process that initiates the activity of the inactive enzyme MAP kinase kinase kinase during osmolarity sensing.
168	activation of MAPKK activity involved in osmosensory signaling pathway	P	Any process that initiates the activity of the inactive enzyme MAP kinase kinase during osmolarity sensing.
169	activation of MAPK activity involved in osmosensory signaling pathway	P	Any process that initiates the activity of the inactive enzyme MAP kinase activity during osmolarity sensing.
170	sphingosine hydroxylase activity	F	Catalysis of the hydroxylation of sphingolipid long chain bases.
171	ribonuclease MRP activity	F	Catalysis of the site-specific cleavage of RNA by a catalytic RNA-mediated mechanism; substrates include the A3 site in the ITS1 of pre-rRNA.
172	ribonuclease MRP complex	C	A ribonucleoprotein complex that contains an RNA molecule of the snoRNA family, and cleaves the rRNA precursor as part of rRNA transcript processing. It also has other roles: In S. cerevisiae it is involved in cell cycle-regulated degradation of daughter cell-specific mRNAs, while in mammalian cells it also enters the mitochondria and processes RNAs to create RNA primers for DNA replication.
173	inactivation of MAPK activity involved in osmosensory signaling pathway	P	Any process that terminates the activity of the active enzyme MAP kinase during osmolarity sensing.
175	3'-5'-exoribonuclease activity	F	Catalysis of the sequential cleavage of mononucleotides from a free 3' terminus of an RNA molecule.
176	nuclear exosome (RNase complex)	C	A ribonuclease complex that has 3-prime to 5-prime processive and distributive hydrolytic exoribonuclease activity and endoribonuclease activity, producing 5-prime-phosphomonoesters. Participates in a multitude of cellular RNA processing and degradation events preventing nuclear export and/or translation of aberrant RNAs. Restricted to processing linear and circular single-stranded RNAs (ssRNA) only. RNAs with complex secondary structures may have to be unwound or pre-processed by co-factors prior to entering the complex, esp if the 3-prime end is structured.
177	cytoplasmic exosome (RNase complex)	C	A ribonuclease complex that has 3-prime to 5-prime processive hydrolytic exoribonuclease activity producing 5-prime-phosphomonoesters. Participates in a multitude of cellular RNA processing and degradation events preventing nuclear export and/or translation of aberrant RNAs. Restricted to processing linear and circular single-stranded RNAs (ssRNA) only. RNAs with complex secondary structures may have to be unwound or pre-processed by co-factors prior to entering the complex, esp if the 3-prime end is structured.
178	exosome (RNase complex)	C	A ribonuclease complex that has 3-prime to 5-prime exoribonuclease activity and possibly endoribonuclease activity, producing 5-prime-phosphomonoesters. Participates in a multitude of cellular RNA processing and degradation events preventing nuclear export and/or translation of aberrant RNAs. Restricted to processing linear and circular single-stranded RNAs (ssRNA) only. RNAs with complex secondary structures may have to be unwound or pre-processed by co-factors prior to entering the complex, esp if the 3-prime end is structured.
179	rRNA (adenine-N6,N6-)-dimethyltransferase activity	F	Catalysis of the dimethylation two adjacent A residues in the loop closing the 3'-terminal stem of the 18S rRNA, using S-adenosyl-L-methionine as a methyl donor.
182	rDNA binding	F	Interacting selectively and non-covalently with DNA sequences encoding ribosomal RNA.
183	chromatin silencing at rDNA	P	Repression of transcription of ribosomal DNA by altering the structure of chromatin.
184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	P	The nonsense-mediated decay pathway for nuclear-transcribed mRNAs degrades mRNAs in which an amino-acid codon has changed to a nonsense codon; this prevents the translation of such mRNAs into truncated, and potentially harmful, proteins.
185	activation of MAPKKK activity	P	Any process that initiates the activity of the inactive enzyme MAP kinase kinase kinase (MAPKKK).
186	activation of MAPKK activity	P	The initiation of the activity of the inactive enzyme MAP kinase kinase (MAPKK).
187	activation of MAPK activity	P	The initiation of the activity of the inactive enzyme MAP kinase (MAPK).
188	inactivation of MAPK activity	P	Any process that terminates the activity of the active enzyme MAP kinase.
189	MAPK import into nucleus	P	The directed movement of a MAP kinase to the nucleus upon activation.
196	MAPK cascade involved in cell wall organization or biogenesis	P	A MAPK cascade that contributes to cell wall organization or biogenesis.
197	activation of MAPKKK activity involved in cell wall organization or biogenesis	P	Any process that initiates the activity of the inactive enzyme MAP kinase kinase kinase in the context of cell wall organization or biogenesis.
198	activation of MAPKK activity involved in cell wall organization or biogenesis	P	Any process that initiates the activity of the inactive enzyme MAP kinase kinase in the context of cell wall organization or biogenesis.
199	activation of MAPK activity involved in cell wall organization or biogenesis	P	Any process that initiates the activity of the inactive enzyme MAP kinase in the context of cell wall biogenesis, the assembly and arrangement of the cell wall, the rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal and most prokaryotic cells.
200	inactivation of MAPK activity involved in cell wall organization or biogenesis	P	Any process that terminates the activity of the active enzyme MAP kinase in the context of cell wall organization or biogenesis.
201	MAPK import into nucleus involved in cell wall organization or biogenesis	P	The directed movement of a MAP kinase to the nucleus that occurs in the context of cell wall organization or biogenesis.
208	MAPK import into nucleus involved in osmosensory signaling pathway	P	The directed movement of a MAP kinase to the nucleus during osmolarity sensing.
209	protein polyubiquitination	P	Addition of multiple ubiquitin groups to a protein, forming a ubiquitin chain.
210	NAD+ diphosphatase activity	F	Catalysis of the reaction: NAD+ + H2O = AMP + NMN.
212	meiotic spindle organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the microtubule spindle during a meiotic cell cycle.
213	tRNA-intron endonuclease activity	F	Catalysis of the endonucleolytic cleavage of pre-tRNA, producing 5'-hydroxyl and 2',3'-cyclic phosphate termini, and specifically removing the intron.
214	tRNA-intron endonuclease complex	C	A protein complex that catalyzes the endonucleolytic cleavage of pre-tRNA, producing 5'-hydroxyl and 2',3'-cyclic phosphate termini, and specifically removing the intron.
215	tRNA 2'-phosphotransferase activity	F	Catalysis of the reaction: 2'-phospho-[ligated tRNA] + NAD+ = mature tRNA + ADP ribose 1'',2''-phosphate + nicotinamide + H2O. This reaction is the transfer of the splice junction 2-phosphate from ligated tRNA to NAD+ to produce ADP-ribose 1'-2' cyclic phosphate.
217	DNA secondary structure binding	F	Interacting selectively and non-covalently with DNA containing secondary structure elements such as four-way junctions, bubbles, loops, Y-form DNA, or double-strand/single-strand junctions.
220	vacuolar proton-transporting V-type ATPase, V0 domain	C	The V0 domain of a proton-transporting V-type ATPase found in the vacuolar membrane.
221	vacuolar proton-transporting V-type ATPase, V1 domain	C	The V1 domain of a proton-transporting V-type ATPase found in the vacuolar membrane.
222	plasma membrane proton-transporting V-type ATPase, V0 domain	C	The V0 domain of a proton-transporting V-type ATPase found in the plasma membrane.
223	plasma membrane proton-transporting V-type ATPase, V1 domain	C	The V1 domain of a proton-transporting V-type ATPase found in the plasma membrane.
224	peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity	F	Catalysis of the reaction: 4-N-(N-acetyl-D-glucosaminyl)-protein + H2O = N-acetyl-beta-D-glucosaminylamine + peptide L-aspartate. This reaction is the hydrolysis of an N4-(acetyl-beta-D-glucosaminyl)asparagine residue in which the N-acetyl-D-glucosamine residue may be further glycosylated, to yield a (substituted) N-acetyl-beta-D-glucosaminylamine and the peptide containing an aspartic residue.
225	N-acetylglucosaminylphosphatidylinositol deacetylase activity	F	Catalysis of the reaction: N-acetyl-D-glucosaminylphosphatidylinositol + H2O = D-glucosaminylphosphatidylinositol + acetate. This reaction is the second step of the biosynthesis of glycosylphosphatidylinositol (GPI), used to anchor various eukaryotic proteins to the cell-surface membrane.
226	microtubule cytoskeleton organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins.
227	oxaloacetate secondary active transmembrane transporter activity	F	Catalysis of the transfer of oxaloacetate from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Chemiosmotic sources of energy include uniport, symport or antiport.
228	nuclear chromosome	C	A chromosome that encodes the nuclear genome and is found in the nucleus of a eukaryotic cell during the cell cycle phases when the nucleus is intact.
229	cytoplasmic chromosome	C	A chromosome found in the cytoplasm.
234	phosphoethanolamine N-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + ethanolamine phosphate = S-adenosyl-L-homocysteine + N-methylethanolamine phosphate.
235	astral microtubule	C	Any of the spindle microtubules that radiate in all directions from the spindle poles and are thought to contribute to the forces that separate the poles and position them in relation to the rest of the cell.
236	mitotic prometaphase	P	The cell cycle phase in higher eukaryotes which follows mitotic prophase and during which the nuclear envelope is disrupted and breaks into membrane vesicles, and the spindle microtubules enter the nuclear region. Kinetochores mature on each centromere and attach to some of the spindle microtubules. Kinetochore microtubules begin the process of aligning chromosomes in one plane halfway between the poles.
237	leptotene	P	The cell cycle phase which is the first stage of prophase I in meiosis, and during which the chromosomes first become visible.
238	zygotene	P	The cell cycle phase which follows leptotene during prophase I of meiosis, and during which each chromosome pairs with its homolog; the two become aligned and crossing over may occur.
239	pachytene	P	The cell cycle phase which follows zygotene during prophase I of meiosis, and during which crossing over occurs between a chromatid in one partner and another chromatid in the homologous chromosome.
240	diplotene	P	The cell cycle phase which follows pachytene during prophase I of meiosis, during which the homologous chromosomes begin to separate and the synaptonemal complex dissolves.
241	diakinesis	P	The cell cycle phase which follows diplotene during prophase I of meiosis, the separation of homologous chromosomes is complete and crossing over has occurred.
242	pericentriolar material	C	A network of small fibers that surrounds the centrioles in cells; contains the microtubule nucleating activity of the centrosome.
243	commitment complex	C	A spliceosomal complex that is formed by association of the U1 snRNP with the 5' splice site of an unspliced intron in an RNA transcript.
244	spliceosomal tri-snRNP complex assembly	P	The formation of a tri-snRNP complex containing U4 and U6 (or U4atac and U6atac) snRNAs and U5 snRNAs and associated proteins. This includes reannealing of U4 and U6 (or U4atac and U6atac) snRNAs released from previous rounds of splicing to reform the U4/U6 snRNP (or U4atac/U6atac snRNP) as well as the subsequent association of the U5 snRNP with the U4/U6 snRNP (or U4atac/U6atac snRNP) to form a tri-snRNP that is ready to reassemble into another spliceosome complex.
245	spliceosomal complex assembly	P	The aggregation, arrangement and bonding together of a spliceosomal complex, a ribonucleoprotein apparatus that catalyzes nuclear mRNA splicing via transesterification reactions.
246	delta24(24-1) sterol reductase activity	F	Catalysis of the reaction: ergosterol + NADP(+) = ergosta-5,7,22,24(24(1))-tetraen-3beta-ol + H(+) + NADPH.
247	C-8 sterol isomerase activity	F	Catalysis of the reaction which results in unsaturation at C-7 in the B ring of sterols.
248	C-5 sterol desaturase activity	F	Catalysis of the reaction: 5,7,24(28)-ergostatrienol + O2 + NADPH = 5,7,22,24(28)-ergostatetraenol + 2 H2O + NADP+.
249	C-22 sterol desaturase activity	F	Catalysis of the formation of the C-22(23) double bond in the sterol side chain. An example reaction: 5,7,24(28)-ergostatrienol + O2 + NADPH = 5,7,22,24(28)-ergostatetraenol + 2 H2O + NADP+.
250	lanosterol synthase activity	F	Catalysis of the reaction: (S)-2,3-epoxysqualene = lanosterol. This is a cyclization reaction that forms the sterol nucleus.
252	C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity	F	Catalysis of the reaction: 3-beta-hydroxy-4-beta-methyl-5-alpha-cholesta-8,24-dien-4-alpha-carboxylate + NAD(P)+ = 4-alpha-methyl-5-alpha-cholesta-8,24-dien-3-one + CO2 + NAD(P)H.
253	3-keto sterol reductase activity	F	Catalysis of the reaction: a 3-beta-hydroxyl sterol + NADP+ = a 3-keto sterol + NADPH + H(+).
254	C-4 methylsterol oxidase activity	F	Catalysis of the reaction: 4,4-dimethyl-5-alpha-cholesta-8,24-dien-3-beta-ol + NAD(P)H + H(+) + O2 = 4-beta-hydroxymethyl-4-alpha-methyl-5-alpha-cholesta-8,24-dien-3-beta-ol + NAD(P)+ + H2O.
255	allantoin metabolic process	P	The chemical reactions and pathways involving allantoin, (2,5-dioxo-4-imidazolidinyl)urea, an intermediate or end product of purine catabolism.
256	allantoin catabolic process	P	The chemical reactions and pathways resulting in the breakdown of allantoin, (2,5-dioxo-4-imidazolidinyl)urea.
257	nitrilase activity	F	Catalysis of the reaction: a nitrile + H2O = a carboxylate + NH3. Acts on a wide range of aromatic nitriles including (indole-3-yl)-acetonitrile and some aliphatic nitriles, and on the corresponding acid amides.
262	mitochondrial chromosome	C	A chromosome found in the mitochondrion of a eukaryotic cell.
266	mitochondrial fission	P	The division of a mitochondrion within a cell to form two or more separate mitochondrial compartments.
268	peroxisome targeting sequence binding	F	Interacting selectively and non-covalently with a peroxisomal targeting sequence, any of several sequences of amino acids within a protein that can act as a signal for the localization of the protein into the peroxisome.
269	toxin export channel activity	F	Enables the energy independent passage of toxins, sized less than 1000 Da, across a membrane towards the outside of the cell. The transmembrane portions of porins consist exclusively of beta-strands which form a beta-barrel. They are found in the outer membranes of Gram-negative bacteria, mitochondria, plastids and possibly acid-fast Gram-positive bacteria.
270	peptidoglycan metabolic process	P	The chemical reactions and pathways involving peptidoglycans, any of a class of glycoconjugates found only in bacterial cell walls and consisting of strands of glycosaminoglycan cross-linked by oligopeptides to form a huge and rigid network.
271	polysaccharide biosynthetic process	P	The chemical reactions and pathways resulting in the formation of a polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically.
272	polysaccharide catabolic process	P	The chemical reactions and pathways resulting in the breakdown of a polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically.
274	mitochondrial proton-transporting ATP synthase, stator stalk	C	One of two stalks that connect the catalytic core of the hydrogen-transporting ATP synthase to the mitochondrial membrane-associated F0 proteins; is thought to prevent futile rotation of the catalytic core.
275	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)	C	The catalytic sector of the mitochondrial hydrogen-transporting ATP synthase; it comprises the catalytic core and central stalk, and is peripherally associated with the mitochondrial inner membrane when the entire ATP synthase is assembled.
276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)	C	All non-F1 subunits of the mitochondrial hydrogen-transporting ATP synthase, including integral and peripheral mitochondrial inner membrane proteins.
277	[cytochrome c]-lysine N-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + cytochrome c L-lysine = S-adenosyl-L-homocysteine + cytochrome c N6-methyl-L-lysine. This is the addition of a methyl group to the N6 atom of a lysine residue in cytochrome c.
278	mitotic cell cycle	P	Progression through the phases of the mitotic cell cycle, the most common eukaryotic cell cycle, which canonically comprises four successive phases called G1, S, G2, and M and includes replication of the genome and the subsequent segregation of chromosomes into daughter cells. In some variant cell cycles nuclear replication or nuclear division may not be followed by cell division, or G1 and G2 phases may be absent.
279	M phase	P	A cell cycle phase during which nuclear division occurs, and which is comprises the phases: prophase, metaphase, anaphase and telophase.
280	nuclear division	P	The division of a cell nucleus into two nuclei, with DNA and other nuclear contents distributed between the daughter nuclei.
281	mitotic cytokinesis	P	A cell cycle process that results in the division of the cytoplasm of a cell after mitosis, resulting in the separation of the original cell into two daughter cells.
282	cellular bud site selection	P	The specification of the site where a daughter cell will form, in organisms that reproduce by budding. An example of this process is found in Saccharomyces cerevisiae.
285	1-phosphatidylinositol-3-phosphate 5-kinase activity	F	Catalysis of the reaction: a 1-phosphatidyl-1D-myo-inositol 3-phosphate + ATP = a 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate + ADP + 2 H(+).
286	alanine dehydrogenase activity	F	Catalysis of the reaction: L-alanine + H2O + NAD+ = pyruvate + NH3 + NADH + H(+).
287	magnesium ion binding	F	Interacting selectively and non-covalently with magnesium (Mg) ions.
288	nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	P	A major pathway of degradation of nuclear-transcribed mRNAs that proceeds through a series of ordered steps that includes poly(A) tail shortening and that can regulate mRNA stability.
289	nuclear-transcribed mRNA poly(A) tail shortening	P	Shortening of the poly(A) tail of a nuclear-transcribed mRNA from full length to an oligo(A) length.
290	deadenylation-dependent decapping of nuclear-transcribed mRNA	P	Cleavage of the 5'-cap of a nuclear mRNA triggered by shortening of the poly(A) tail to below a minimum functional length.
291	nuclear-transcribed mRNA catabolic process, exonucleolytic	P	The chemical reactions and pathways resulting in the breakdown of the transcript body of a nuclear-transcribed mRNA that occurs when the ends are not protected by the 5'-cap or the 3'-poly(A) tail.
292	RNA fragment catabolic process	P	The chemical reactions and pathways resulting in the breakdown of a fragment of RNA, such as excised introns or sequences removed from ribosomal RNA during processing.
293	ferric-chelate reductase activity	F	Catalysis of the reaction: 2 Fe2+ + NAD+ = 2 Fe3+ + NADH + H(+).
294	nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay	P	A minor degradation pathway nuclear-transcribed mRNAs that begins with an endonucleolytic cleavage to generate unprotected ends.
295	adenine nucleotide transmembrane transporter activity	F	Catalysis of the transfer of adenine nucleotides (AMP, ADP, and ATP) from one side of the membrane to the other.
296	spermine transport	P	The directed movement of spermine, N,N-bis(3-aminopropyl)-1,4-diaminobutane, a polyamine formed by the transfer of a propylamine group from decarboxylated S-adenosylmethionine to spermidine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
297	spermine transmembrane transporter activity	F	Enables the transfer of spermine from one side of the membrane to the other. Spermine is a polybasic amine found in human sperm, in ribosomes and in some viruses, which is involved in nucleic acid packaging. Synthesis is regulated by ornithine decarboxylase which plays a key role in control of DNA replication.
298	endopolyphosphatase activity	F	Catalysis of the reaction: polyphosphate + n H2O = (n+1) oligophosphate. The product contains 4 or 5 phosphate residues.
301	retrograde transport, vesicle recycling within Golgi	P	The retrograde movement of substances within the Golgi, mediated by COP I vesicles. Cis-Golgi vesicles are constantly moving forward through the Golgi stack by cisternal progression, eventually becoming trans-Golgi vesicles. They then selectively transport membrane and luminal proteins from the trans- to the medial-Golgi while leaving others behind in the trans-Golgi cisternae; similarly, they selectively move proteins from the medial- to the cis-Golgi.
302	response to reactive oxygen species	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a reactive oxygen species stimulus. Reactive oxygen species include singlet oxygen, superoxide, and oxygen free radicals.
303	response to superoxide	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a superoxide stimulus. Superoxide is the anion, oxygen-, formed by addition of one electron to dioxygen (O2) or any compound containing the superoxide anion.
304	response to singlet oxygen	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a singlet oxygen stimulus. Singlet oxygen is a dioxygen (O2) molecule in which two 2p electrons have similar spin. Singlet oxygen is more highly reactive than the form in which these electrons are of opposite spin, and it is produced in mutant chloroplasts lacking carotenoids and by leukocytes during metabolic burst.
305	response to oxygen radical	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oxygen radical stimulus. An oxygen radical is any oxygen species that carries a free electron; examples include hydroxyl radicals and the superoxide anion.
306	extrinsic component of vacuolar membrane	C	The component of a vacuolar membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
307	cyclin-dependent protein kinase holoenzyme complex	C	Cyclin-dependent protein kinases (CDKs) are enzyme complexes that contain a kinase catalytic subunit associated with a regulatory cyclin partner.
308	cytoplasmic cyclin-dependent protein kinase holoenzyme complex	C	Cyclin-dependent protein kinase (CDK) complex found in the cytoplasm.
309	nicotinamide-nucleotide adenylyltransferase activity	F	Catalysis of the reaction: ATP + nicotinamide nucleotide = diphosphate + NAD+.
310	xanthine phosphoribosyltransferase activity	F	Catalysis of the reaction: 5-phospho-alpha-D-ribose 1-diphosphate + xanthine = (9-D-ribosylxanthine)-5'-phosphate + diphosphate.
311	plastid large ribosomal subunit	C	The larger of the two subunits of a plastid ribosome. Two sites on the ribosomal large subunit are involved in translation: the aminoacyl site (A site) and peptidyl site (P site).
312	plastid small ribosomal subunit	C	The smaller of the two subunits of a plastid ribosome.
313	organellar ribosome	C	A ribosome contained within a subcellular membrane-bounded organelle.
314	organellar small ribosomal subunit	C	The smaller of the two subunits of an organellar ribosome.
315	organellar large ribosomal subunit	C	The larger of the two subunits of an organellar ribosome. Two sites on the ribosomal large subunit are involved in translation: the aminoacyl site (A site) and peptidyl site (P site).
316	sulfite transport	P	The directed movement of sulfite into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
319	sulfite transmembrane transporter activity	F	Enables the transfer of sulfite ions from one side of a membrane to the other.
320	re-entry into mitotic cell cycle	P	The resumption of the mitotic cell division cycle by cells that were in a quiescent or other non-dividing state.
321	re-entry into mitotic cell cycle after pheromone arrest	P	The resumption of the mitotic cell division cycle by pheromone-arrested cells that have not mated. An example of this process is found in Saccharomyces cerevisiae.
322	storage vacuole	C	A vacuole that functions primarily in the storage of materials, including nutrients, pigments, waste products, and small molecules.
323	lytic vacuole	C	A vacuole that is maintained at an acidic pH and which contains degradative enzymes, including a wide variety of acid hydrolases.
324	fungal-type vacuole	C	A vacuole that has both lytic and storage functions. The fungal vacuole is a large, membrane-bounded organelle that functions as a reservoir for the storage of small molecules (including polyphosphate, amino acids, several divalent cations (e.g. calcium), other ions, and other small molecules) as well as being the primary compartment for degradation. It is an acidic compartment, containing an ensemble of acid hydrolases. At least in S. cerevisiae, there are indications that the morphology of the vacuole is variable and correlated with the cell cycle, with logarithmically growing cells having a multilobed, reticulated vacuole, while stationary phase cells contain a single large structure.
325	plant-type vacuole	C	A closed structure that is completely surrounded by a unit membrane, contains liquid, and retains the same shape regardless of cell cycle phase. An example of this structure is found in Arabidopsis thaliana.
326	protein storage vacuole	C	A storage vacuole that contains a lytic vacuole; identified in plants.
327	lytic vacuole within protein storage vacuole	C	A membrane-bounded compartment containing crystals of phytic acid and proteins characteristic of a lytic vacuole, found within a storage vacuole.
328	fungal-type vacuole lumen	C	The volume enclosed within the vacuolar membrane of a vacuole, the shape of which correlates with cell cycle phase. An example of this structure is found in Saccharomyces cerevisiae.
329	fungal-type vacuole membrane	C	The lipid bilayer surrounding a vacuole, the shape of which correlates with cell cycle phase. The membrane separates its contents from the cytoplasm of the cell. An example of this structure is found in Saccharomyces cerevisiae.
330	plant-type vacuole lumen	C	The volume enclosed within the vacuolar membrane of a vacuole that retains the same shape regardless of cell cycle phase. An example of this is found in Arabidopsis thaliana.
331	contractile vacuole	C	A specialized vacuole of eukaryotic cells, especially Protozoa, that fills with water from the cytoplasm and then discharges this externally by the opening of contractile vacuole pores. Its function is probably osmoregulatory.
332	template for synthesis of G-rich strand of telomere DNA activity	F	Provision of the template used by reverse transcriptase to synthesize the G-rich strand of telomeric DNA.
333	telomerase catalytic core complex	C	The minimal catalytic core of telomerase is a ribonucleoprotein complex composed of a catalytic reverse transcriptase subunit and an RNA subunit that provides the template for telomeric DNA addition.
334	3-hydroxyanthranilate 3,4-dioxygenase activity	F	Catalysis of the reaction: 3-hydroxyanthranilate + O(2) = cis,cis-2-amino-3-(3-oxoprop-1-enyl)but-2-enedioate + H(+).
335	negative regulation of transposition, DNA-mediated	P	Any process that stops, prevents, or reduces the frequency, rate or extent of DNA transposition.
336	positive regulation of transposition, DNA-mediated	P	Any process that activates or increases the frequency, rate or extent of DNA transposition.
337	regulation of transposition, DNA-mediated	P	Any process that modulates the frequency, rate or extent of DNA transposition, the process of transposing (moving to a different location) a segment of a chromosome or a piece of a DNA molecule.
338	protein deneddylation	P	The removal of a ubiquitin-like protein of the NEDD8 type from a protein.
339	RNA cap binding	F	Interacting selectively and non-covalently with a 7-methylguanosine (m7G) group or derivative located at the 5' end of an RNA molecule.
340	RNA 7-methylguanosine cap binding	F	Interacting selectively and non-covalently with the 7-methylguanosine group added cotranscriptionally to the 5' end of RNA molecules transcribed by polymerase II.
341	RNA trimethylguanosine cap binding	F	Interacting selectively and non-covalently with the trimethylguanosine (m(3)(2,2,7)-GTP) group located at the 5' end of some RNA molecules. Such trimethylated cap structures, generally produced by posttranscriptional modification of a 7-methylguanosine cap, are often found on snRNAs and snoRNAs transcribed by RNA polymerase II, but have also be found on snRNAs transcribed by RNA polymerase III. They have also been found on a subset of the mRNA population in some species, e.g. C. elegans.
342	RNA cap 4 binding	F	Interacting selectively and non-covalently with a hypermethylated cap structure consisting of 7-methylguanosine (m(7)G) followed by four methylated nucleotides (cap 4): 7-methylguanosine-ppp-N6, N6, 2'-O-trimethyladenosine-p-2'-O-methyladenosine-p-2'-O-methylcytosine-p-N3, 2'-O-dimethyluridine Such caps are known to be found at the 5' ends of SL RNAs of trypanosomatid protozoa.
343	plastid-encoded plastid RNA polymerase complex A	C	A plastid-encoded DNA-directed RNA polymerase complex that resembles eubacterial multisubunit RNA polymerases, with a core composed of alpha, beta, and beta-prime subunits. An additional subunit, a sigma factor, is required for promoter recognition. PEP-A is generated from the PEP-B form during chloroplast maturation to generate a complex composed of at least thirteen polypeptides that is not sensitive to the antibiotic rifampicin, like its precursor form the PEP-B complex.
344	plastid-encoded plastid RNA polymerase complex B	C	A plastid-encoded DNA-directed RNA polymerase complex that resembles eubacterial multisubunit RNA polymerases with a core composed of alpha, beta, and beta-prime subunits. An additional subunit, a sigma factor, is required for promoter recognition. PEP-B is distinguished from PEP-A by its sensitivity to the antibiotic rifampicin. PEP-B is found in both etioplasts and chloroplasts, but is the predominate form in etioplasts. It forms the core of the PEP-A form; the conversion from PEP-B to PEP-A occurs during chloroplast maturation.
345	cytosolic DNA-directed RNA polymerase complex	C	The eubacterial DNA-directed RNA polymerase is a multisubunit complex with a core composed of the essential subunits beta-prime, beta, and two copies of alpha and a fifth nonessential subunit called omega. An additional subunit, a sigma factor, is required for promoter recognition and specificity.
346	transcription export complex	C	The transcription export (TREX) complex couples transcription elongation by RNA polymerase II to mRNA export. The complex associates with the polymerase and travels with it along the length of the transcribed gene. TREX is composed of the THO transcription elongation complex as well as other proteins that couple THO to mRNA export proteins. The TREX complex is known to be found in a wide range of eukaryotes, including S. cerevisiae and metazoans.
347	THO complex	C	The THO complex is a nuclear complex that is required for transcription elongation through genes containing tandemly repeated DNA sequences. The THO complex is also part of the TREX (TRanscription EXport) complex that is involved in coupling transcription to export of mRNAs to the cytoplasm. In S. cerevisiae, it is composed of four subunits: Hpr1p, Tho2p, Thp1p, and Mft1p, while the human complex is composed of 7 subunits.
348	mRNA branch site recognition	P	Recognition of the pre-mRNA branch site sequence by components of the assembling spliceosome.
349	generation of catalytic spliceosome for first transesterification step	P	Formation of a catalytic spliceosome complex ready to perform the first splicing reaction. This occurs by an ATP-dependent conformational change of the pre-catalytic spliceosome.
350	generation of catalytic spliceosome for second transesterification step	P	Conformational rearrangement of the spliceosomal complex containing the RNA products from the 1st step of splicing to form the catalytic site for the second step of splicing.
352	trans assembly of SL-containing precatalytic spliceosome	P	Assembly of a spliceosomal complex containing the SL RNA and the pre-mRNA to be joined, as well as all the spliceosomal snRNPs involved in trans leader splicing. Formation of the trans leader spliceosome brings together the quadruple SL/U4/U5/U6 snRNP and the complex of the U2 snRNP with the splice site of the pre-mRNA.
353	formation of quadruple SL/U4/U5/U6 snRNP	P	Formation of a quadruple snRNP complex composed of the spliced leader (SL) RNA along with the U4/U6-U5 tri-snRNP complex. Interactions that may facilitate this include a duplex between the SL and U6 RNAs and interactions between the U5 RNA and the exon sequence at the 5' splice site within the SL RNA.
354	cis assembly of pre-catalytic spliceosome	P	Assembly of a spliceosomal complex containing the intact pre-mRNA and all of the spliceosomal snRNPs. This occurs when the tri-snRNP associates with the pre-mRNA and associated snRNPs in an ATP-dependent manner.
365	mRNA trans splicing, via spliceosome	P	The joining together of exons from two different primary transcripts of messenger RNA (mRNA) via a spliceosomal mechanism, so that mRNA consisting only of the joined exons is produced.
366	intergenic mRNA trans splicing	P	The joining together of two independently transcribed RNAs from two different genes, each of which also produces mRNA(s) via cis-splicing.
372	Group I intron splicing	P	The splicing of Group I introns. This occurs by a ribozymic mechanism where the intron sequence forms a distinct 3D structure, characteristic of Group I introns and involved in determining the locations of the splice sites (there do not appear to be consensus splice site sequences) as well as having a role in catalyzing the splicing reactions, though protein factors are also required in vivo. Splicing occurs by a series of two transesterification reactions, generally with exogenous guanosine as the initiating nucleophile. The intron is excised as a linear piece (though it may subsequently circularize).
373	Group II intron splicing	P	The splicing of Group II introns. This occurs by a ribozymic mechanism where the intron sequence forms a distinct 3D structure, characteristic of Group II introns and containing splice site consensus sequences, that is involved in catalyzing the splicing reactions, though protein factors are also required in vivo. Splicing occurs by a series of two transesterification reactions (mechanistically similar to those for splicing of nuclear mRNAs) initiated by a bulged adenosine residue within the intron sequence as the initiating nucleophile. The intron is excised as a lariat.
374	Group III intron splicing	P	The splicing of Group III introns. This occurs by a ribozymic mechanism where the intron sequence forms a distinct 3D structure, characteristic of Group III introns, that is involved in catalyzing the splicing reactions, though protein factors are also required in vivo. Splicing occurs by a series of two transesterification reactions begun by a bulged adenosine residue within the intron sequence as the initiating nucleophile. The intron is excised as a lariat. Though very similar in structure and mechanism to Group II introns, Group III introns are smaller and more streamlined and the splice site consensus sequences are not as well conserved.
375	RNA splicing, via transesterification reactions	P	Splicing of RNA via a series of two transesterification reactions.
376	RNA splicing, via transesterification reactions with guanosine as nucleophile	P	Splicing of RNA via a series of two transesterification reactions with exogenous guanosine as the initiating nucleophile.
377	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile	P	Splicing of RNA via a series of two transesterification reactions with a bulged adenosine residue from the intron branch point as the initiating nucleophile. When the initial RNA for the splicing reaction is a single molecule (cis splicing), the excised intron is released in a lariat structure.
378	RNA exon ligation	P	The RNA metabolic process that joins two exons, each of which has free ends that were generated by endonucleolytic cleavages, by a ligation reaction.
379	tRNA-type intron splice site recognition and cleavage	P	RNA processing that begins when the tertiary structure of a tRNA type intron is recognized, and ends when the endonucleolytic cleavage of the RNA at both the 5' and 3' splice sites occurs.
380	alternative mRNA splicing, via spliceosome	P	The process of generating multiple mRNA molecules from a given set of exons by differential use of exons from the primary transcript(s) to form multiple mature mRNAs that vary in their exon composition.
381	regulation of alternative mRNA splicing, via spliceosome	P	Any process that modulates the frequency, rate or extent of alternative splicing of nuclear mRNAs.
384	first spliceosomal transesterification activity	F	Catalysis of the first transesterification reaction of spliceosomal mRNA splicing. The intron branch site adenosine is the nucleophile attacking the 5' splice site, resulting in cleavage at this position. In cis splicing, this is the step that forms a lariat structure of the intron RNA, while it is still joined to the 3' exon.
386	second spliceosomal transesterification activity	F	Catalysis of the second transesterification reaction of spliceosomal mRNA splicing. Ligation of the two exons occurs via a transesterification reaction where the free 3'-hydroxyl group of the 5' exon is the nucleophile attacking the 3' splice site. Non-expressed sequences are now detached from the exons. In cis splicing, the intron is in a lariat structure.
387	spliceosomal snRNP assembly	P	The aggregation, arrangement and bonding together of one or more snRNA and multiple protein components to form a ribonucleoprotein complex that is involved in formation of the spliceosome.
388	spliceosome conformational change to release U4 (or U4atac) and U1 (or U11)	P	Rearrangement of the pre-catalytic spliceosome containing U4 (or U4atac) and U1 (or U11) snRNPs to unpair U4 (or U4atac) from U6 (or U6atac) and release it from the spliceosomal complex along with U1 (or U11).
389	mRNA 3'-splice site recognition	P	Recognition of the intron 3'-splice site by components of the assembling U2- or U12-type spliceosome.
390	spliceosomal complex disassembly	P	Disassembly of a spliceosomal complex with the ATP-dependent release of the product RNAs, one of which is composed of the joined exons. In cis splicing, the other product is the excised sequence, often a single intron, in a lariat structure.
393	spliceosomal conformational changes to generate catalytic conformation	P	Structural rearrangements of the spliceosome complex, containing RNA to be spliced, to generate a catalytic conformation.
394	RNA splicing, via endonucleolytic cleavage and ligation	P	Splicing of RNA via recognition of the folded RNA structure that brings the 5' and 3' splice sites into proximity and cleavage of the RNA at both the 3' and 5' splice sites by an endonucleolytic mechanism, followed by ligation of the exons.
395	mRNA 5'-splice site recognition	P	Recognition of the intron 5'-splice site by components of the assembling spliceosome.
398	mRNA splicing, via spliceosome	P	The joining together of exons from one or more primary transcripts of messenger RNA (mRNA) and the excision of intron sequences, via a spliceosomal mechanism, so that mRNA consisting only of the joined exons is produced.
399	cellular bud neck septin structure	C	Any of a series of septin structures that are localized in the bud neck of a budding fungal cell during the cell cycle.
400	four-way junction DNA binding	F	Interacting selectively and non-covalently with DNA containing four-way junctions, also known as Holliday junctions, a structure where two DNA double strands are held together by reciprocal exchange of two of the four strands, one strand each from the two original helices.
401	open form four-way junction DNA binding	F	Interacting selectively and non-covalently with DNA containing the open form of a four-way junction, also known as a Holliday junction, a structure where two DNA double strands are held together by reciprocal exchange of two of the four strands, one strand each from the two original helices. The open form of a four-way junction can be diagrammed without any of the strands crossing over.
402	crossed form four-way junction DNA binding	F	Interacting selectively and non-covalently with DNA containing the crossed form of a four-way junction, also known as a Holliday junction, a structure where two DNA double strands are held together by reciprocal exchange of two of the four strands, one strand each from the two original helices. The crossed form of a four-way junction cannot be diagrammed without any of the strands crossing over, and instead contains a single crossover between two of the strands.
403	Y-form DNA binding	F	Interacting selectively and non-covalently with segment of DNA shaped like a Y. This shape occurs when DNA contains a region of paired double-stranded DNA on one end and a region of unpaired DNA strands on the opposite end.
404	heteroduplex DNA loop binding	F	Interacting selectively and non-covalently with DNA containing a loop. A loop occurs when DNA contains a large insertion or deletion that causes a region of unpaired single-stranded DNA to loop out, while the rest of the DNA is in a paired double-stranded configuration.
405	bubble DNA binding	F	Interacting selectively and non-covalently with DNA that contains a bubble. A bubble occurs when DNA contains a region of unpaired, single-stranded DNA flanked on both sides by regions of paired, double-stranded DNA.
406	double-strand/single-strand DNA junction binding	F	Interacting selectively and non-covalently with a region of DNA that contains double-stranded DNA flanked by a region of single-stranded DNA.
407	pre-autophagosomal structure	C	A punctate structure localized in the vicinity of the vacuole that is required for the formation of autophagosomes.
408	EKC/KEOPS complex	C	A protein complex involved in t6A tRNA modification; originally proposed to be involved in transcription as well as promoting telomere uncapping and telomere elongation. For example, in Saccharomyces cerevisiae the complex contains Bud32p, Kae1p, Gon7p, Cgi121p, and Pcc1p.
409	regulation of transcription by galactose	P	Any process involving galactose that modulates the frequency, rate or extent or transcription.
410	negative regulation of transcription by galactose	P	Any process involving galactose that stops, prevents or reduces the rate of transcription.
411	positive regulation of transcription by galactose	P	Any process involving galactose that activates or increases the rate of transcription.
412	histone peptidyl-prolyl isomerization	P	The modification of a histone by cis-trans isomerization of a proline residue.
413	protein peptidyl-prolyl isomerization	P	The modification of a protein by cis-trans isomerization of a proline residue.
414	regulation of histone H3-K36 methylation	P	Any process that modulates the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 36 of histone H3.
415	negative regulation of histone H3-K36 methylation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 36 of histone H3.
416	positive regulation of histone H3-K36 methylation	P	Any process that activates or increases the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 36 of histone H3.
417	HIR complex	C	A protein complex proposed to be involved in replication-independent nucleosome assembly, by promoting histone deposition onto DNA. For example, in Saccharomyces, the complex contains Hir1p, Hir2p, Hir3p, and Hpc2p.
418	DNA-directed RNA polymerase IV complex	C	RNA polymerase IV is a multisubunit RNA polymerase complex found in the nucleus of plants and involved in accumulation of siRNAs and in DNA methylation-dependent silencing of endogenous repeated sequences. Pol IV is composed of subunits that are paralogous or identical to the 12 subunits of Pol II. The largest and second-largest subunits of Pol IV are the catalytic subunits and share similarity with the corresponding subunits of other eukaryotic and bacterial multisubunit RNA polymerases. The second largest subunit is also found in RNA polymerase V, while the largest subunit is found only in RNAP IV complex.
419	DNA-directed RNA polymerase V complex	C	RNA polymerase V is a multisubunit RNA polymerase complex found in the nucleus of plants and involved in accumulation of siRNAs and in DNA methylation-dependent silencing of endogenous repeated sequences. Pol V is composed of subunits that are paralogous or identical to the 12 subunits of Pol II. Two large subunits comprise the most conserved portion including the catalytic site and share similarity with other eukaryotic and bacterial multisubunit RNA polymerases. The second largest subunit is also found in RNA polymerase IVa, while the largest subunit is found only in the IVa complex and contains an extended C-terminal domain (CTD) that includes multiple repeats of a 16 amino-acid consensus sequence as well as other sequences. The remainder of the complex is composed of smaller subunits.
421	autophagosome membrane	C	The lipid bilayer surrounding an autophagosome, a double-membrane-bounded vesicle in which endogenous cellular material is sequestered.
422	mitophagy	P	The autophagic process in which mitochondria are delivered to the vacuole and degraded in response to changing cellular conditions.
423	macromitophagy	P	Degradation of a mitochondrion by macroautophagy.
424	microautophagy of mitochondrion	P	Degradation of a mitochondrion by lysosomal microautophagy.
425	macropexophagy	P	Degradation of a peroxisome by macroautophagy.
426	micropexophagy	P	Degradation of a peroxisome by lysosomal microautophagy.
427	plastid-encoded plastid RNA polymerase complex	C	An RNA polymerase complex containing polypeptides encoded by the plastid genome. Plastid-encoded DNA-directed RNA polymerases resemble eubacterial multisubunit RNA polymerases, with a core composed of alpha, beta, and beta-prime subunits. Some forms contain multiple additional subunits. An additional sigma factor subunit is required for promoter recognition.
428	DNA-directed RNA polymerase complex	C	A protein complex that possesses DNA-directed RNA polymerase activity.
429	carbon catabolite regulation of transcription from RNA polymerase II promoter	P	A transcription regulation process in which the presence of one carbon source leads to the modulation of the frequency, rate, or extent of transcription, from an RNA polymerase II promoter, of specific genes involved in the metabolism of other carbon sources.
430	regulation of transcription from RNA polymerase II promoter by glucose	P	Any process involving glucose that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter.
431	regulation of transcription from RNA polymerase II promoter by galactose	P	Any process involving galactose that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter.
432	positive regulation of transcription from RNA polymerase II promoter by glucose	P	Any process involving glucose that activates or increases the rate of transcription from an RNA polymerase II promoter.
433	negative regulation of transcription from RNA polymerase II promoter by glucose	P	Any process involving glucose that stops, prevents or reduces the rate of transcription from an RNA polymerase II promoter.
434	negative regulation of transcription from RNA polymerase II promoter by galactose	P	Any process involving galactose that stops, prevents or reduces the rate of transcription from an RNA polymerase II promoter.
435	positive regulation of transcription from RNA polymerase II promoter by galactose	P	Any process involving galactose that activates or increases the rate of transcription from an RNA polymerase II promoter.
436	carbon catabolite activation of transcription from RNA polymerase II promoter	P	Any process involving carbon catabolites that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
437	carbon catabolite repression of transcription from RNA polymerase II promoter	P	A transcription regulation process in which the presence of one carbon source leads to a decrease in the frequency, rate, or extent of transcription, from an RNA polymerase II promoter, of specific genes involved in the metabolism of other carbon sources.
438	core TFIIH complex portion of holo TFIIH complex	C	The core TFIIH complex when it is part of the general transcription factor TFIIH.
439	core TFIIH complex	C	The 7 subunit core of TFIIH that is a part of either the general transcription factor holo-TFIIH or the nucleotide-excision repair factor 3 complex. In S. cerevisiae/humans the complex is composed of: Ssl2/XPB, Tfb1/p62, Tfb2/p52, Ssl1/p44, Tfb4/p34, Tfb5/p8 and Rad3/XPD.
440	core TFIIH complex portion of NEF3 complex	C	The core TFIIH complex when it is part of the nucleotide-excision repair factor 3 (NEF3).
444	MIS12/MIND type complex	C	A multiprotein kinetochore subcomplex that binds to centromeric chromatin and forms part of the inner kinetochore. It helps to recruit outer kinetochore subunits that will bind to microtubules. In humans, it consists of MIS12, DSN1, NSL1 and PMF1.
445	THO complex part of transcription export complex	C	The THO complex when it is part of the TREX (TRanscription EXport) complex that is involved in coupling transcription to export of mRNAs to the cytoplasm. In S. cerevisiae, it is composed of four subunits: Hpr1, Tho2, Thp1, and Mft1, while the human complex is composed of 7 subunits.
446	nucleoplasmic THO complex	C	The THO complex when it is acting as a nuclear complex that is required for transcription elongation through genes containing tandemly repeated DNA sequences. In S. cerevisiae, it is composed of four subunits: Hpr1, Tho2, Thp2, and Mft1, while the human complex is composed of 7 subunits.
447	endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	P	Endonucleolytic cleavage between the SSU-rRNA and the 5.8S rRNA of an rRNA molecule originally produced as a tricistronic rRNA transcript that contained the Small SubUnit (SSU) rRNA, the 5.8S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript.
448	cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	P	Endonucleolytic cleavage within ITS2 between the 5.8S rRNA and the LSU-rRNA of an rRNA molecule originally produced as a tricistronic rRNA transcript that contained the Small SubUnit (SSU) rRNA, the 5.8S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript.
449	endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 5S)	P	Endonucleolytic cleavage of a pre-rRNA molecule originally produced as a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, the Large Subunit (LSU) rRNA, and the 5S rRNA, in that order, from 5' to 3' along the primary transcript. For example, primary ribosomal RNA transcripts containing three genes, in this order, are produced in E. coli and other prokaryotic species. Note that the use of the word tricistronic refers only to the number of mature rRNA molecules which will be produced from the primary transcript and ignores tRNAs that may also be present within the primary transcript.
450	cleavage of bicistronic rRNA transcript (SSU-rRNA, LSU-rRNA)	P	Endonucleolytic cleavage of pre-rRNAs originally produced as a bicistronic rRNA transcript that contains the SSU-rRNA and the LSU-rRNA in that order from 5' to 3' along the primary transcript. Primary ribosomal RNA transcripts with two genes in this order are produced in Archaeal species.
451	rRNA 2'-O-methylation	P	The addition of a methyl group to the 2'-oxygen atom of a nucleotide residue in an rRNA molecule during ribosome biogenesis.
452	snoRNA guided rRNA 2'-O-methylation	P	The posttranscriptional addition of methyl groups to the 2'-oxygen atom of nucleotide residues in an rRNA molecule during ribosome biogenesis using a snoRNA guide that targets the position of methylation.
453	enzyme-directed rRNA 2'-O-methylation	P	The addition of methyl groups to the 2'-oxygen atom of nucleotide residues in an rRNA molecule during ribosome biogenesis where the methylase specifies the site that becomes methylated without using a guide RNA.
454	snoRNA guided rRNA pseudouridine synthesis	P	The intramolecular conversion of uridine to pseudouridine in an rRNA molecule during ribosome biogenesis using a snoRNA guide that targets the position of pseudouridylation.
455	enzyme-directed rRNA pseudouridine synthesis	P	The intramolecular conversion of uridine to pseudouridine during ribosome biogenesis where the enzyme specifies the site that becomes pseudouridylated without using a guide RNA.
456	dimethylation involved in SSU-rRNA maturation	P	Dimethylation of the N6 amino groups of two consecutive adenosine residues near the 3'-end of the SSU rRNA. This process has been conserved from bacteria to eukaryotes.
457	endonucleolytic cleavage between SSU-rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 5S)	P	Endonucleolytic cleavage to separate a pre-SSU-rRNA from a pre-LSU-rRNA originally produced as a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, the Large Subunit (LSU) rRNA, and the 5S rRNA, in that order, from 5' to 3' along the primary transcript. Note that the use of the word tricistronic refers only to the number of mature rRNA molecules which will be produced from the primary transcript and ignores tRNAs that may also be present within the primary transcript.
458	endonucleolytic cleavage between LSU-rRNA and 5S rRNA of tricistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 5S)	P	Endonucleolytic cleavage to separate a pre-LSU-rRNA from a pre-5S rRNA originally produced as a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, the Large Subunit (LSU) rRNA, and the 5S rRNA, in that order, from 5' to 3' along the primary transcript. Note that the use of the word tricistronic refers only to the number of mature rRNA molecules which will be produced from the primary transcript and ignores tRNAs that may also be present within the primary transcript.
459	exonucleolytic trimming involved in rRNA processing	P	Exonucleolytic digestion of a pre-rRNA molecule in the process to generate a mature rRNA molecule.
460	maturation of 5.8S rRNA	P	Any process involved in the maturation of a precursor 5.8S ribosomal RNA (rRNA) molecule into a mature 5.8S rRNA molecule.
461	endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	P	Endonucleolytic cleavage at the 3'-end of the SSU-rRNA from an originally tricistronic rRNA transcript that contained the Small Subunit (SSU) rRNA, the 5.8S rRNA, and the Large Subunit (LSU) rRNA in that order from 5' to 3' along the primary transcript, to produce the mature end of the SSU-rRNA.
462	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	P	Any process involved in the maturation of a precursor Small SubUnit (SSU) ribosomal RNA (rRNA) molecule into a mature SSU-rRNA molecule from the pre-rRNA molecule originally produced as a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, 5.8S rRNA, and the Large Subunit (LSU) in that order from 5' to 3' along the primary transcript.
463	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	P	Any process involved in the maturation of a precursor Large SubUnit (LSU) ribosomal RNA (rRNA) molecule into a mature LSU-rRNA molecule from the pre-rRNA molecule originally produced as a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, 5.8S rRNA, and Large Subunit (LSU) in that order from 5' to 3' along the primary transcript.
464	endonucleolytic cleavage in ITS1 upstream of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	P	Endonucleolytic cleavage within Internal Transcribed Spacer 1 (ITS1) upstream of the 5.8S rRNA derived from an originally tricistronic rRNA transcript that contained the Small Subunit (SSU) rRNA, the 5.8S rRNA, and the Large Subunit (LSU) rRNA in that order from 5' to 3' along the primary transcript. In S. cerevisiae, this endonucleolytic cleavage within ITS1 initiates the maturation of the LSU and the 5.8S rRNAs.
465	exonucleolytic trimming to generate mature 5'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	P	Exonucleolytic digestion of a pre-rRNA molecule to generate the mature 5'-end of a 5.8S rRNA molecule derived from an originally tricistronic pre-rRNA transcript that contained the Small Subunit (SSU) rRNA, the 5.8S rRNA, and the Large Subunit (LSU) rRNA in that order from 5' to 3' along the primary transcript.
466	maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	P	Any process involved in the maturation of an rRNA molecule originally produced as part of a tricistronic rRNA transcript that contained the Small SubUnit (SSU) rRNA, the 5.8S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript.
467	exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	P	Exonucleolytic digestion of a pre-rRNA molecule to generate the mature 3'-end of a 5.8S rRNA molecule derived from an originally tricistronic pre-rRNA transcript that contained the Small Subunit (SSU) rRNA, the 5.8S rRNA, and the Large Subunit (LSU) rRNA in that order from 5' to 3' along the primary transcript.
468	generation of mature 3'-end of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	P	Any process involved in generating the mature 3'-end of an LSU-rRNA derived from a tricistronic rRNA transcript that contained the Small SubUnit (SSU) rRNA, the 5.8S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript.
469	cleavage involved in rRNA processing	P	Any phosphodiester bond hydrolysis involved in the conversion of a primary ribosomal RNA (rRNA) transcript into a mature rRNA molecule.
470	maturation of LSU-rRNA	P	Any process involved in the maturation of a precursor Large SubUnit (LSU) ribosomal RNA (rRNA) molecule into a mature LSU-rRNA molecule.
471	endonucleolytic cleavage in 3'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	P	Endonucleolytic cleavage within the 3'-External Transcribed Spacer (ETS) of a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, the 5.8S rRNA, and the Large Subunit (LSU) rRNA in that order from 5' to 3' along the primary transcript. In S. cerevisiae, endonucleolytic cleavage within the 3'-ETS of the pre-RNA, which may occur cotranscriptionally, is the first step in rRNA processing, and initiates a cascade of subsequent processing and modification events.
472	endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	P	Endonucleolytic cleavage between the 5'-External Transcribed Spacer (5'-ETS) and the 5' end of the SSU-rRNA of a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, the 5.8S rRNA, and the Large Subunit (LSU) rRNA in that order from 5' to 3' along the primary transcript, to produce the mature end of the SSU-rRNA.
473	maturation of LSU-rRNA from tetracistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, 2S rRNA, LSU-rRNA)	P	Any process involved in the maturation of a precursor Large SubUnit (LSU) ribosomal RNA (rRNA) molecule into a mature LSU-rRNA molecule from the pre-rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, 5.8 S rRNA, 2S rRNA, and Large Subunit (LSU) in that order from 5' to 3' along the primary transcript.
474	maturation of SSU-rRNA from tetracistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, 2S rRNA, LSU-rRNA)	P	Any process involved in the maturation of a precursor Small SubUnit (SSU) ribosomal RNA (rRNA) molecule into a mature SSU-rRNA molecule from the pre-rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, 5.8 S rRNA, 2S rRNA, and Large Subunit (LSU) in that order from 5' to 3' along the primary transcript.
475	maturation of 2S rRNA	P	Any process involved in the maturation of a precursor 2S ribosomal RNA (rRNA) molecule into a mature 2S rRNA molecule.
476	maturation of 4.5S rRNA	P	Any process involved in the maturation of a precursor 4.5S ribosomal RNA (rRNA) molecule into a mature 4.5S rRNA molecule.
477	generation of mature 5'-end of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	P	Cleavage within ITS2 to generate the mature 5'-end of an LSU-rRNA derived from a tricistronic rRNA transcript that contained the Small SubUnit (SSU) rRNA, the 5.8S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript.
478	endonucleolytic cleavage involved in rRNA processing	P	Any endonucleolytic cleavage involved in the conversion of a primary ribosomal RNA (rRNA) transcript into a mature rRNA molecule. Some endonucleolytic cleavages produce the mature end, while others are a step in the process of generating the mature end from the pre-rRNA.
479	endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	P	Endonucleolytic cleavage of a pre-rRNA molecule originally produced as a tricistronic rRNA transcript that contains the Small SubUnit (SSU) rRNA, the 5.8S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript. Primary ribosomal RNA transcripts with three genes, in this order, are produced in the nuclei of many eukaryotic species, including S. cerevisiae.
480	endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	P	Endonucleolytic cleavage within the 5'-External Transcribed Spacer (ETS) of a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, the 5.8S rRNA, and the Large Subunit (LSU) rRNA in that order from 5' to 3' along the primary transcript. Endonucleolytic cleavage within the 5'-ETS of the pre-RNA is conserved as one of the early steps of rRNA processing in all eukaryotes, but the specific position of cleavage is variable.
481	maturation of 5S rRNA	P	Any process involved in the maturation of a precursor 5S ribosomal RNA (rRNA) molecule into a mature 5S rRNA molecule.
482	maturation of 5S rRNA from tetracistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	P	Any process involved in the maturation of a precursor 5S ribosomal RNA (rRNA) molecule into a mature 5S rRNA molecule from the pre-rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, Large Subunit (LSU) the 4.5S rRNA, and the 5S rRNA in that order from 5' to 3' along the primary transcript.
483	endonucleolytic cleavage of tetracistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, 2S rRNA, LSU-rRNA)	P	Endonucleolytic cleavage of a pre-rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small SubUnit (SSU) rRNA, the 5.8S rRNA, 2S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript. Primary ribosomal RNA transcripts with four genes, in this order, are produced in the nuclei of D. melanogaster as well as in those of other dipteran species.
484	cleavage between SSU-rRNA and 5.8S rRNA of tetracistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, 2S rRNA, LSU-rRNA)	P	Endonucleolytic cleavage between the SSU-rRNA and the 5.8S rRNA of an rRNA molecule originally produced as a tetracistronic rRNA transcript that contained the Small SubUnit (SSU) rRNA, the 5.8S rRNA, 2S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript.
485	cleavage between 2S rRNA and LSU-rRNA of tetracistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, 2S rRNA, LSU-rRNA)	P	Endonucleolytic cleavage between the LSU-rRNA and the 2S rRNA of an rRNA molecule originally produced as a tetracistronic rRNA transcript that contained the Small SubUnit (SSU) rRNA, the 5.8S rRNA, 2S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript.
486	cleavage between 5.8S rRNA and 2S rRNA of tetracistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, 2S rRNA, LSU-rRNA)	P	Endonucleolytic cleavage between the 5.8S rRNA and the 2S rRNA of an rRNA molecule originally produced as a tetracistronic rRNA transcript that contained the Small SubUnit (SSU) rRNA, the 5.8S rRNA, 2S rRNA, and the Large SubUnit (LSU) rRNA, in that order, from 5' to 3' along the primary transcript.
487	maturation of 5.8S rRNA from tetracistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, 2S rRNA, LSU-rRNA)	P	Any process involved in the maturation of a precursor 5.8S ribosomal RNA (rRNA) molecule into a mature 5.8S rRNA molecule from the pre-rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, the 8.8S rRNA, the 2S rRNA, and the Large Subunit (LSU) in that order from 5' to 3' along the primary transcript.
488	maturation of LSU-rRNA from tetracistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 4.5S-rRNA, 5S-rRNA)	P	Any process involved in the maturation of a precursor Large SubUnit (LSU) ribosomal RNA (rRNA) molecule into a mature LSU-rRNA molecule from the pre-rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, Large Subunit (LSU) the 4.5S rRNA, and the 5S rRNA in that order from 5' to 3' along the primary transcript.
489	maturation of SSU-rRNA from tetracistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 4.5S-rRNA, 5S-rRNA)	P	Any process involved in the maturation of a precursor Small SubUnit (SSU) ribosomal RNA (rRNA) molecule into a mature SSU-rRNA molecule from the pre-rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, Large Subunit (LSU) the 4.5S rRNA, and the 5S rRNA in that order from 5' to 3' along the primary transcript.
491	small nucleolar ribonucleoprotein complex assembly	P	The aggregation, arrangement and bonding together of proteins and a snoRNA to form a small nucleolar ribonucleoprotein (snoRNP) complex.
492	box C/D snoRNP assembly	P	The aggregation, arrangement and bonding together of proteins and a box C/D snoRNA to form a box C/D small nucleolar ribonucleoprotein (snoRNP) complex.
493	box H/ACA snoRNP assembly	P	The aggregation, arrangement and bonding together of proteins and a box H/ACA snoRNA to form a box H/ACA small nucleolar ribonucleoprotein (snoRNP) complex.
494	box C/D snoRNA 3'-end processing	P	Any process involved in forming the mature 3' end of a box C/D snoRNA molecule.
495	box H/ACA snoRNA 3'-end processing	P	Any process involved in forming the mature 3' end of a box H/ACA snoRNA molecule.
496	base pairing	F	Interacting selectively and non-covalently with nucleic acid via hydrogen bonds between the bases of a gene product molecule and the bases of a target nucleic acid molecule.
497	base pairing with DNA	F	Interacting selectively and non-covalently with nucleic acid via hydrogen bonds between the bases of a gene product molecule and the bases of a target DNA molecule.
498	base pairing with RNA	F	Interacting selectively and non-covalently with ribonucleic acid (RNA) via hydrogen bonds between the bases of a gene product molecule and the bases of a target RNA molecule.
499	base pairing with mRNA	F	Interacting selectively and non-covalently with messenger ribonucleic acid (mRNA) via hydrogen bonds between the bases of a gene product molecule and the bases of a target mRNA molecule.
500	RNA polymerase I upstream activating factor complex	C	A complex required for the transcription of rDNA by RNA polymerase I. In yeast the complex consists of Rrrn5p, Rrn9p, Rrn10p, histones H3 and H4, and Uaf30p.
501	flocculation via cell wall protein-carbohydrate interaction	P	The reversible, non-sexual aggregation of cells mediated by the binding of proteins in the cell wall of one cell to carbohydrates in the cell wall of another cell. An example of this process is found in Saccharomyces cerevisiae, in which it is pH- and calcium-dependent.
502	proteasome complex	C	A large multisubunit complex which catalyzes protein degradation, found in eukaryotes, archaea and some bacteria. In eukaryotes, this complex consists of the barrel shaped proteasome core complex and one or two associated proteins or complexes that act in regulating entry into or exit from the core.
506	glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex	C	An enzyme complex that catalyzes the transfer of GlcNAc from UDP-GlcNAc to an acceptor phosphatidylinositol, the first step in the production of GPI anchors for cell surface proteins. The complex contains PIG-A, PIG-C, PIG-H, PIG-Q, PIG-P, and DPM2 in human, and Eri1p, Gpi1p, Gpi2p, Gpi15p, Gpi19p, and Spt14p in budding yeast.
578	embryonic axis specification	P	The establishment, maintenance and elaboration of a pattern along a line or a point in an embryo.
700	mismatch base pair DNA N-glycosylase activity	F	Catalysis of the removal of single bases present in mismatches by the cleavage the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar. The reaction releases a free base and leaves an apurinic/apyrimidinic (AP) site.
701	purine-specific mismatch base pair DNA N-glycosylase activity	F	Catalysis of the removal of purines present in mismatches, especially opposite oxidized purines, by cleaving the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar. The reaction releases a free base and leaves an apurinic (AP) site.
702	oxidized base lesion DNA N-glycosylase activity	F	Catalysis of the removal of oxidized bases by cleaving the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar. The reaction releases a free base and leaves an apurinic/apyrimidinic (AP) site.
703	oxidized pyrimidine nucleobase lesion DNA N-glycosylase activity	F	Catalysis of the removal oxidized pyrimidine bases by cleaving the N-C1' glycosidic bond between the oxidized pyrimidine and the deoxyribose sugar. The reaction involves formation of a covalent enzyme-pyrimidine base intermediate. Release of the enzyme and free base by a beta-elimination or a beta, gamma-elimination mechanism results in the cleavage of the DNA backbone 3' of the apyrimidinic (AP) site.
704	pyrimidine dimer DNA N-glycosylase activity	F	Catalysis of the removal of pyrimidine dimers by removing the 5' pyrimidine of the dimer by cleaving the N-C1' glycosidic bond between the 5' pyrimidine of the dimer and the deoxyribose sugar. The reaction releases the 5' pyrimidine of the dimer and leaves an apurinic (AP) site. The reaction involves the formation of a covalent enzyme substrate intermediate. Release of the enzyme and free base by a beta-elimination or a beta, gamma-elimination mechanism results in the cleavage of the DNA backbone 3' of the apyrimidinic (AP) site.
705	achiasmate meiosis I	P	The first division of meiosis in which homologous chromosomes are paired and segregated from each other, occurring in the constitutive absence of chiasmata.
706	meiotic DNA double-strand break processing	P	The cell cycle process in which the 5' to 3' exonucleolytic resection of the DNA at the site of the break to form a 3' single-strand DNA overhang occurs. This takes place during meiosis.
707	meiotic DNA recombinase assembly	P	During meiosis, the aggregation, arrangement and bonding together of strand exchange proteins (recombinases) to form higher order oligomers on single-stranded DNA.
708	meiotic strand invasion	P	The cell cycle process in which the nucleoprotein complex (composed of the broken single-strand DNA and the recombinase) searches and identifies a region of homology in intact duplex DNA. The broken single-strand DNA displaces the like strand and forms Watson-Crick base pairs with its complement, forming a duplex in which each strand is from one of the two recombining DNA molecules. This occurs during meiosis.
709	meiotic joint molecule formation	P	The conversion of the paired broken DNA and homologous duplex DNA into a four-stranded branched intermediate, known as a joint molecule, formed during meiotic recombination. These joint molecules contain Holliday junctions on either side of heteroduplex DNA.
710	meiotic mismatch repair	P	A system for the identification and correction of base-base mismatches, small insertion-deletion loops, and regions of heterology that are present in duplex DNA formed with strands from two recombining molecules. Correction of the mismatch can result in non-Mendelian segregation of alleles following meiosis.
711	meiotic DNA repair synthesis	P	During meiosis, the synthesis of DNA proceeding from the broken 3' single-strand DNA end that uses the homologous intact duplex as the template.
712	resolution of meiotic recombination intermediates	P	The cleavage and rejoining of intermediates, such as Holliday junctions, formed during meiotic recombination to produce two intact molecules in which genetic material has been exchanged.
713	meiotic heteroduplex formation	P	During meiosis, the formation of a stable duplex DNA that contains one strand from each of the two recombining DNA molecules.
714	meiotic strand displacement	P	The cell cycle process in which the broken 3' single-strand DNA molecule that formed heteroduplex DNA with its complement in an intact duplex DNA is rejected. The Watson-Crick base pairing in the original duplex is restored. The rejected 3' single-strand DNA molecule reanneals with its original complement to reform two intact duplex molecules. This occurs during meiosis.
715	nucleotide-excision repair, DNA damage recognition	P	The identification of lesions in DNA, such as pyrimidine-dimers, intrastrand cross-links, and bulky adducts. The wide range of substrate specificity suggests the repair complex recognizes distortions in the DNA helix.
716	transcription-coupled nucleotide-excision repair, DNA damage recognition	P	The identification of lesions on the actively transcribed strand of the DNA duplex as well as a small subset of lesions not recognized by the general nucleotide-excision repair pathway.
717	nucleotide-excision repair, DNA duplex unwinding	P	The unwinding, or local denaturation, of the DNA duplex to create a bubble around the site of the DNA damage.
718	nucleotide-excision repair, DNA damage removal	P	The removal of the oligonucleotide that contains the DNA damage. The oligonucleotide is formed by dual incisions that flank the site of DNA damage.
719	photoreactive repair	P	The repair of UV-induced T-T, C-T and C-C dimers by directly reversing the damage to restore the original pyrimidines.
720	pyrimidine dimer repair by nucleotide-excision repair	P	The repair of UV-induced T-T, C-T, and C-C dimers by the recognition and removal of the damaged DNA strand from the DNA helix as an oligonucleotide. The small gap left in the DNA helix is filled in by the sequential action of DNA polymerase and DNA ligase.
721	(R,R)-butanediol dehydrogenase activity	F	Catalysis of the reversible reaction: (R,R)-butane-2,3-diol + NAD+ = (R)-acetoin + NADH + H(+).
722	telomere maintenance via recombination	P	Any recombinational process that contributes to the maintenance of proper telomeric length.
723	telomere maintenance	P	Any process that contributes to the maintenance of proper telomeric length and structure by affecting and monitoring the activity of telomeric proteins, the length of telomeric DNA and the replication and repair of the DNA. These processes includes those that shorten, lengthen, replicate and repair the telomeric DNA sequences.
724	double-strand break repair via homologous recombination	P	The error-free repair of a double-strand break in DNA in which the broken DNA molecule is repaired using homologous sequences. A strand in the broken DNA searches for a homologous region in an intact chromosome to serve as the template for DNA synthesis. The restoration of two intact DNA molecules results in the exchange, reciprocal or nonreciprocal, of genetic material between the intact DNA molecule and the broken DNA molecule.
725	recombinational repair	P	A DNA repair process that involves the exchange, reciprocal or nonreciprocal, of genetic material between the broken DNA molecule and a homologous region of DNA.
726	non-recombinational repair	P	A DNA repair process in which that does not require the exchange of genetic material between the broken DNA molecule and a homologous region of DNA.
727	double-strand break repair via break-induced replication	P	The error-free repair of a double-strand break in DNA in which the centromere-proximal end of a broken chromosome searches for a homologous region in an intact chromosome. DNA synthesis initiates from the 3' end of the invading DNA strand, using the intact chromosome as the template, and progresses to the end of the chromosome.
728	gene conversion at mating-type locus, DNA double-strand break formation	P	The site-specific endonucleolytic cleavage of DNA at the mating-type locus which initiates the conversion of one mating-type allele to another.
729	DNA double-strand break processing	P	The 5' to 3' exonucleolytic resection of the DNA at the site of the break to form a 3' single-strand DNA overhang.
730	DNA recombinase assembly	P	The aggregation, arrangement and bonding together of strand exchange proteins (recombinases) into higher order oligomers on single-stranded DNA.
731	DNA synthesis involved in DNA repair	P	Synthesis of DNA that proceeds from the broken 3' single-strand DNA end and uses the homologous intact duplex as the template.
732	strand displacement	P	The rejection of the broken 3' single-strand DNA molecule that formed heteroduplex DNA with its complement in an intact duplex DNA. The Watson-Crick base pairing in the original duplex is restored. The rejected 3' single-strand DNA molecule reanneals with its original complement to reform two intact duplex molecules.
733	DNA strand renaturation	P	The identification and annealing of complementary base pairs in single-strand DNA.
734	gene conversion at mating-type locus, DNA repair synthesis	P	Synthesis of DNA that proceeds from the broken 3' single-strand DNA end uses the homologous intact duplex as the template during gene conversion at the mating-type locus.
735	removal of nonhomologous ends	P	The removal of nonhomologous sequences at the broken 3' single-strand DNA end before DNA repair synthesis can occur.
736	double-strand break repair via single-strand annealing, removal of nonhomologous ends	P	During DSBR via single-strand annealing, the removal of nonhomologous sequences at the broken 3' single-strand DNA end before DNA repair synthesis can occur.
737	DNA catabolic process, endonucleolytic	P	The chemical reactions and pathways resulting in the breakdown of DNA, involving the hydrolysis of internal 3',5'-phosphodiester bonds in one or two strands of deoxyribonucleotides.
738	DNA catabolic process, exonucleolytic	P	The chemical reactions and pathways resulting in the breakdown of DNA, involving the hydrolysis of terminal 3',5'-phosphodiester bonds in one or two strands of deoxyribonucleotides.
740	nuclear membrane fusion	P	The joining of 2 or more lipid bilayer membranes that surround the nucleus.
741	karyogamy	P	The creation of a single nucleus from multiple nuclei as a result of fusing the lipid bilayers that surround each nuclei.
742	karyogamy involved in conjugation with cellular fusion	P	During sexual reproduction, the creation of a single nucleus from multiple nuclei as a result of fusing the lipid bilayers that surround each nuclei. This occurs after cytogamy.
743	nuclear migration involved in conjugation with cellular fusion	P	The microtubule-based movement of nuclei towards one another as a prelude to karyogamy in organisms undergoing conjugation with cellular fusion.
744	karyogamy involved in conjugation with mutual genetic exchange	P	During sexual reproduction, the creation of a single nucleus from multiple nuclei as a result of fusing the lipid bilayers that surround each nuclei. This occurs after the mutual exchange of nuclei.
745	nuclear migration involved in conjugation with mutual genetic exchange	P	The net movement of nuclei towards one another, leading to the bilateral transfer of genetic material in organisms undergoing conjugation without cellular fusion.
746	conjugation	P	The union or introduction of genetic information from compatible mating types that results in a genetically different individual. Conjugation requires direct cellular contact between the organisms.
747	conjugation with cellular fusion	P	A conjugation process that results in the union of cellular and genetic information from compatible mating types. An example of this process is found in Saccharomyces cerevisiae.
748	conjugation with mutual genetic exchange	P	A conjugation process that results in the mutual exchange and union of only genetic information between compatible mating types. Conjugation without cellular fusion requires direct cellular contact between the organisms without plasma membrane fusion. The organisms involved in conjugation without cellular fusion separate after nuclear exchange.
749	response to pheromone involved in conjugation with cellular fusion	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pheromone stimulus that contributes to the process of conjugation with cellular fusion. An example of this process is found in Saccharomyces cerevisiae.
750	pheromone-dependent signal transduction involved in conjugation with cellular fusion	P	A signal transduction process resulting in the relay, amplification or dampening of a signal generated in response to pheromone exposure in organisms that undergo conjugation with cellular fusion. An example of this process is found in Saccharomyces cerevisiae.
751	mitotic cell cycle G1 arrest in response to pheromone	P	The cell cycle regulatory process in which the mitotic cell cycle is halted during G1 as a result of a pheromone stimulus. An example of this process is found in Saccharomyces cerevisiae.
752	agglutination involved in conjugation with cellular fusion	P	During conjugation with cellular fusion, the aggregation or adhesion of compatible mating types via complementary cell-cell interactions. An example of this process is agglutination in Saccharomyces cerevisiae.
753	cell morphogenesis involved in conjugation with cellular fusion	P	The change in form (cell shape and size) that occurs during sexual reproduction in order to facilitate direct contact between the compatible mating types in organisms that undergo conjugation cellular fusion.
754	adaptation of signaling pathway by response to pheromone involved in conjugation with cellular fusion	P	In organisms that undergo conjugation with cellular fusion, the process resulting in desensitization following exposure to pheromone stimulus that act to down-regulate further stimulation or block initial conjugation responses. An example of this is the adaptation to pheromone during conjugation with cellular fusion in Saccharomyces cerevisiae.
755	cytogamy	P	During conjugation with cellular fusion, the process resulting in creating a single cell from complementary mating types. The localized remodeling and dissolution of external protective structures allow the fusion of the plasma membranes and cytoplasmic mixing. An example of this process is found in Saccharomyces cerevisiae.
756	response to pheromone involved in conjugation with mutual genetic exchange	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pheromone stimulus during the process of conjugation without cellular fusion.
757	signal transduction involved in conjugation with mutual genetic exchange	P	A signal transduction process resulting in the relay, amplification or dampening of a signal generated in response to pheromone exposure in organisms that undergo conjugation without cellular fusion.
758	agglutination involved in conjugation with mutual genetic exchange	P	During conjugation without cellular fusion, the aggregation or adhesion of compatible mating types via complementary cell-cell interactions.
759	cell morphogenesis involved in conjugation with mutual genetic exchange	P	The change in form (cell shape and size) that occurs during sexual reproduction in order to facilitate direct contact between the compatible mating types in organisms that undergo conjugation without cellular fusion.
760	adaptation to pheromone involved in conjugation with mutual genetic exchange	P	In organisms that undergo conjugation without cellular fusion, the process resulting in desensitization following exposure to pheromone stimulus that act to down-regulate further stimulation or block initial conjugation responses.
761	conjugant formation	P	During conjugation without cellular fusion, the process that results in pairing complementary mating types. Localized morphological, cytological, and cytoskeletal changes connect the mating types without cytoplasmic mixing.
762	pheromone-induced unidirectional conjugation	P	The process of unidirectional (polarized) transfer of genetic information in response to a pheromone. It involves direct cellular contact between a donor and recipient cell; the contact is followed by the formation of a cellular bridge that physically connects the cells; some or all of the chromosome(s) of one cell ('male') is then transferred into the other cell ('female'); unidirectional conjugation occurs between cells of different mating types.
765	response to pheromone involved in pheromone-induced unidirectional conjugation	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pheromone stimulus that contributes to the process of pheromone-induced unidirectional conjugation.
766	negative adaptation of signaling pathway by response to pheromone involved in pheromone-induced unidirectional conjugation	P	In organisms that undergo pheromone-induced unidirectional conjugation, the process involved in desensitization following exposure to pheromone stimulus that acts to down-regulate further stimulation or block initial conjugation responses.
767	cell morphogenesis involved in conjugation	P	The change in form (cell shape and size) that occurs during sexual reproduction in order to facilitate direct contact between the compatible mating types.
768	syncytium formation by plasma membrane fusion	P	The formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells.
769	syncytium formation by mitosis without cytokinesis	P	The formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by one or more rounds of nuclear division without cytokinesis.
770	peptide pheromone export	P	The directed movement of a peptide pheromone out of a cell by a secretion or export pathway used solely for the export of peptide pheromones.
771	agglutination involved in conjugation	P	The aggregation or adhesion of compatible mating types via complementary cell-cell interactions prior to the formation of irreversible cellular contacts during conjugation.
772	mating pheromone activity	F	The activity of binding to and activating specific cell surface receptors, thereby inducing a behavioral or physiological response(s) from a responding organism or cell that leads to the transfer or union of genetic material between organisms or cells. The mating pheromone can either be retained on the cell surface or secreted.
773	phosphatidyl-N-methylethanolamine N-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + phosphatidyl-N-methylethanolamine = S-adenosyl-L-homocysteine + phosphatidyl-N-dimethylethanolamine.
774	adenyl-nucleotide exchange factor activity	F	Stimulates the hydrolysis and exchange of adenyl nucleotides by other proteins.
775	chromosome, centromeric region	C	The region of a chromosome that includes the centromeric DNA and associated proteins. In monocentric chromosomes, this region corresponds to a single area of the chromosome, whereas in holocentric chromosomes, it is evenly distributed along the chromosome.
776	kinetochore	C	A multisubunit complex that is located at the centromeric region of DNA and provides an attachment point for the spindle microtubules.
777	condensed chromosome kinetochore	C	A multisubunit complex that is located at the centromeric region of a condensed chromosome and provides an attachment point for the spindle microtubules.
778	condensed nuclear chromosome kinetochore	C	A multisubunit complex that is located at the centromeric region of a condensed nuclear chromosome and provides an attachment point for the spindle microtubules.
779	condensed chromosome, centromeric region	C	The region of a condensed chromosome that includes the centromere and associated proteins, including the kinetochore. In monocentric chromosomes, this region corresponds to a single area of the chromosome, whereas in holocentric chromosomes, it is evenly distributed along the chromosome.
780	condensed nuclear chromosome, centromeric region	C	The region of a condensed nuclear chromosome that includes the centromere and associated proteins, including the kinetochore. In monocentric chromosomes, this region corresponds to a single area of the chromosome, whereas in holocentric chromosomes, it is evenly distributed along the chromosome.
781	chromosome, telomeric region	C	The terminal region of a linear chromosome that includes the telomeric DNA repeats and associated proteins.
782	telomere cap complex	C	A complex of DNA and protein located at the end of a linear chromosome that protects and stabilizes a linear chromosome.
783	nuclear telomere cap complex	C	A complex of DNA and protein located at the end of a linear chromosome in the nucleus that protects and stabilizes a linear chromosome.
784	nuclear chromosome, telomeric region	C	The terminal region of a linear nuclear chromosome that includes the telomeric DNA repeats and associated proteins.
785	chromatin	C	The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome.
786	nucleosome	C	A complex comprised of DNA wound around a multisubunit core and associated proteins, which forms the primary packing unit of DNA into higher order structures.
787	cytoplasmic nucleosome	C	A complex comprised of DNA wound around a multisubunit core and associated proteins, which forms the primary packing unit of DNA in the cytoplasm into higher order structures.
788	nuclear nucleosome	C	A complex comprised of DNA wound around a multisubunit core and associated proteins, which forms the primary packing unit of DNA in the nucleus into higher order structures.
789	cytoplasmic chromatin	C	The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome in the cytoplasm.
790	nuclear chromatin	C	The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome in the nucleus.
791	euchromatin	C	A dispersed and relatively uncompacted form of chromatin.
792	heterochromatin	C	A compact and highly condensed form of chromatin.
793	condensed chromosome	C	A highly compacted molecule of DNA and associated proteins resulting in a cytologically distinct structure.
794	condensed nuclear chromosome	C	A highly compacted molecule of DNA and associated proteins resulting in a cytologically distinct nuclear chromosome.
795	synaptonemal complex	C	A proteinaceous scaffold found between homologous chromosomes during meiosis.
796	condensin complex	C	A multisubunit protein complex that plays a central role in chromosome condensation.
797	condensin core heterodimer	C	The core heterodimer of a condensin complex, a multisubunit protein complex that plays a central role in chromosome condensation.
798	nuclear cohesin complex	C	A cohesin complex required for cohesion between sister chromatids that remain in the nucleus.
799	nuclear condensin complex	C	A multisubunit protein complex that plays a central role in the condensation of chromosomes that remain in the nucleus.
800	lateral element	C	A proteinaceous core found between sister chromatids during meiotic prophase.
801	central element	C	A structural unit of the synaptonemal complex found between the lateral elements.
802	transverse filament	C	A structural unit of the synaptonemal complex that spans the regions between the lateral elements and connects them.
803	sex chromosome	C	A chromosome involved in sex determination.
804	W chromosome	C	The sex chromosome present in females of species in which the female is the heterogametic sex; generally, the sex chromosome that pairs with the Z chromosome in the heterogametic sex. The W chromosome is absent from the cells of males and present in one copy in the somatic cells of females.
805	X chromosome	C	The sex chromosome present in both sexes of species in which the male is the heterogametic sex. Two copies of the X chromosome are present in each somatic cell of females and one copy is present in males.
806	Y chromosome	C	The sex chromosome present in males of species in which the male is the heterogametic sex; generally, the sex chromosome that pairs with the X chromosome in the heterogametic sex. The Y chromosome is absent from the cells of females and present in one copy in the somatic cells of males.
807	Z chromosome	C	The sex chromosome present in both sexes of species in which the female is the heterogametic sex. Two copies of the Z chromosome are present in each somatic cell of males and one copy is present in females.
808	origin recognition complex	C	A multisubunit complex that is located at the replication origins of a chromosome.
809	cytoplasmic origin of replication recognition complex	C	A multisubunit complex that is located at the replication origins of a chromosome in the cytoplasm.
810	diacylglycerol diphosphate phosphatase activity	F	Catalysis of the reaction: a 1,2-diacyl-sn-glycerol 3-diphosphate + H2O = a 1,2-diacyl-sn-glycerol 3-phosphate + phosphate.
811	GINS complex	C	A heterotetrameric protein complex that associates with replication origins, where it is required for the initiation of DNA replication, and with replication forks.
812	Swr1 complex	C	A multisubunit protein complex that is involved in chromatin remodeling. It is required for the incorporation of the histone variant H2AZ into chromatin. In S. cerevisiae, the complex contains Swr1p, a Swi2/Snf2-related ATPase, and 12 additional subunits.
813	ESCRT I complex	C	An endosomal sorting complex required for transport. It consists of the class E vacuolar protein sorting (Vps) proteins and interacts with ubiquitinated cargoes.
814	ESCRT II complex	C	An endosomal sorting complex required for transport and functions downstream of ESCRT I complex. It consists of the class E vacuolar protein sorting (Vps) proteins and is required for the membrane recruitment of ESCRT III complex and binds to ubiquitinated cargoes.
815	ESCRT III complex	C	An endosomal sorting complex required for transport. Consists of two soluble subcomplexes of highly charged coiled-coil proteins and is required for sorting and/or concentration of multivesicular body (MVB) cargoes.
817	COMA complex	C	A multiprotein complex in yeast consisting of Ctf19p, Okp1p, Mcm21p, and Ame1p. This complex bridges the subunits that are in contact with centromeric DNA and the subunits bound to microtubules during kinetochore assembly.
818	nuclear MIS12/MIND complex	C	A multiprotein kinetochore subcomplex that binds to centromeric chromatin and forms part of the inner kinetochore of a chromosome in the nucleus. It helps to recruit outer kinetochore subunits that will bind to microtubules. Nuclear localization arises in some organisms because the nuclear envelope is not broken down during mitosis. In S. cerevisiae, it consists of at least four proteins: Mtw1p, Nnf1p, Nsl1p, and Dsn1.
819	sister chromatid segregation	P	The cell cycle process in which sister chromatids are organized and then physically separated and apportioned to two or more sets.
820	regulation of glutamine family amino acid metabolic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving amino acids of the glutamine family, comprising arginine, glutamate, glutamine and proline.
821	regulation of arginine metabolic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving arginine, 2-amino-5-(carbamimidamido)pentanoic acid.
822	inositol hexakisphosphate binding	F	Interacting selectively and non-covalently with inositol hexakisphosphate.
823	inositol-1,4,5-trisphosphate 6-kinase activity	F	Catalysis of the reaction: D-myo-inositol 1,4,5-trisphosphate + ATP = D-myo-inositol 1,4,5,6-tetrakisphosphate + ADP + 2 H(+).
824	inositol tetrakisphosphate 3-kinase activity	F	Catalysis of the reaction: ATP + 1D-myo-inositol 1,4,5,6-tetrakisphosphate = ADP + 1D-myo-inositol 1,3,4,5,6-pentakisphosphate.
825	inositol tetrakisphosphate 6-kinase activity	F	Catalysis of the reaction: 1D-myo-inositol 1,3,4,5-tetrakisphosphate + ATP = 1D-myo-inositol 1,3,4,5,6-pentakisphosphate + ADP.
827	inositol-1,3,4,5,6-pentakisphosphate kinase activity	F	Catalysis of the reaction: ATP + 1D-myo-inositol 1,3,4,5,6-pentakisphosphate = ADP + diphospho-1D-myo-inositol tetrakisphosphate. The isomeric configuration of diphospho-1D-myo-inositol tetrakisphosphate is unknown.
828	inositol hexakisphosphate kinase activity	F	Catalysis of the reaction: ATP + 1D-myo-inositol 1,2,3,4,5,6-hexakisphosphate = ADP + diphospho-1D-myo-inositol-pentakisphosphate. The isomeric configuration of diphospho-1D-myo-inositol-pentakisphosphate (PP-IP5) is unknown.
829	inositol heptakisphosphate kinase activity	F	Catalysis of the reaction: ATP + diphospho-1D-myo-inositol-pentakisphosphate = ADP + bis(diphospho)-1D-myo-inositol-tetrakisphosphate. The isomeric configurations of the diphospho-1D-myo-inositol-pentakisphosphate (PP-IP5) and bis(diphospho)-1D-myo-inositol-tetrakisphosphate (bis-PP-IP4) are unknown.
830	inositol hexakisphosphate 4-kinase activity	F	Catalysis of the reaction: ATP + 1D-myo-inositol hexakisphosphate = ADP + 4-diphospho-1D-myo-inositol (1,2,3,5,6)pentakisphosphate.
831	inositol hexakisphosphate 6-kinase activity	F	Catalysis of the reaction: ATP + 1D-myo-inositol hexakisphosphate = ADP + 6-diphospho-1D-myo-inositol (1,2,3,4,5)pentakisphosphate.
832	inositol hexakisphosphate 5-kinase activity	F	Catalysis of the reaction: ATP + 1D-myo-inositol 1,2,3,4,5,6-hexakisphosphate = ADP + 5-diphospho-1D-myo-inositol (1,2,3,4,6)pentakisphosphate.
833	inositol heptakisphosphate 4-kinase activity	F	Catalysis of the reaction: ATP + 5-diphospho-1D-myo-inositol (1,2,3,4,6)pentakisphosphate = 4,5-bisdiphosphoinositol-1D-myoinositol (1,2,3,6)tetrakisphosphate.
834	inositol heptakisphosphate 6-kinase activity	F	Catalysis of the reaction: ATP + 5-diphospho-1D-myo-inositol (1,2,3,4,6)pentakisphosphate = 5,6-bisdiphosphoinositol-1D-myoinositol (1,2,3,4)tetrakisphosphate.
835	ER ubiquitin ligase complex	C	A ubiquitin ligase complex found in the ER.
836	Hrd1p ubiquitin ligase complex	C	A multiprotein complex that recognizes and ubiquitinates proteins with misfolded luminal and membrane domains during ER-associated protein degradation (ERAD). In S. cerevisiae, this complex contains the ubiquitin ligase Hrd1p. In mammals, this complex contains the ubiquitin ligase HRD1 (Synoviolin) or AMFR (gp78).
837	Doa10p ubiquitin ligase complex	C	A multiprotein complex that recognizes and ubiquitinates membrane proteins with misfolded cytosolic domains during ER-associated protein degradation (ERAD). In S. cerevisiae, this complex contains the ubiquitin ligase Ssm4p/Doa10p.
838	Hrd1p ubiquitin ligase ERAD-M complex	C	A multiprotein complex that recognizes and ubiquitinates proteins with misfolded membrane domains during ER-associated protein degradation (ERAD). In S. cerevisiae, this complex contains the ubiquitin ligase Hrd1p.
839	Hrd1p ubiquitin ligase ERAD-L complex	C	A multiprotein complex that recognizes and ubiquitinates proteins with misfolded luminal domains during ER-associated protein degradation (ERAD). In S. cerevisiae, this complex contains the ubiquitin ligase Hrd1p.
900	translation repressor activity, nucleic acid binding	F	Antagonizes the ribosome-mediated translation of mRNA into a polypeptide via direct binding (through a selective and non-covalent interaction) to nucleic acid.
901	translation repressor activity, non-nucleic acid binding	F	Antagonizes the ribosome-mediated translation of mRNA into a polypeptide but does not bind directly to nucleic acid.
902	cell morphogenesis	P	The developmental process in which the size or shape of a cell is generated and organized.
903	regulation of cell shape during vegetative growth phase	P	Any process that modulates the surface configuration of a cell during the vegetative growth phase. The vegetative growth phase is the growth phase during which single celled organisms reproduce by budding or other asexual methods.
904	cell morphogenesis involved in differentiation	P	The change in form (cell shape and size) that occurs when relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history.
905	sporocarp development involved in asexual reproduction	P	The formation of a spore-bearing structure by fungus where spores will arise from asexual reproduction.
906	6,7-dimethyl-8-ribityllumazine synthase activity	F	Catalysis of the reaction: 3,4-dihydroxy-2-butanone-4-phosphate + 5-amino-6-ribitylamino-2,4(1H,3H)-pyrimidinedione = 6,7-dimethyl-8-ribityllumazine + phosphate.
907	sulfonate dioxygenase activity	F	Catalysis of the reaction: sulfonate + 2-oxoglutarate + O2 = sulfite + aminoacetaldehyde + succinate + CO2.
908	taurine dioxygenase activity	F	Catalysis of the reaction: 2-oxoglutarate + O(2) + taurine = aminoacetaldehyde + CO(2) + succinate + sulfite.
909	sporocarp development involved in sexual reproduction	P	The process whose specific outcome is the progression of a fruiting body organ over time, from its formation to the mature structure. The fruiting body is a spore bearing structure. In fungi, the sporocarp (also known as fruiting body) is a multicellular structure on which spore-producing structures, such as basidia or asci, are borne. The fruiting body is part of the sexual phase of a fungal life cycle, with the rest of the life cycle being characterized by vegetative mycelial growth. The sporocarp of a basidiomycete is known as a basidiocarp, while the fruiting body of an ascomycete is known as an ascocarp. A significant range of different shapes and morphologies is found in both basidiocarps and ascocarps; these features play an important role in the identification and taxonomy of fungi.
910	cytokinesis	P	The division of the cytoplasm and the plasma membrane of a cell and its partitioning into two daughter cells.
911	cytokinesis by cell plate formation	P	The process of dividing the cytoplasm of a parent cell where a structure forms in the cytoplasm and grows until reaching the plasma membrane, thereby completely separating the cytoplasms of adjacent progeny cells. An example of this is found in Arabidopsis thaliana.
912	assembly of actomyosin apparatus involved in cytokinesis	P	The assembly and arrangement of an apparatus composed of actin, myosin, and associated proteins that will function in cytokinesis.
913	preprophase band assembly	P	The aggregation, arrangement and bonding together of a set of components to form the preprophase band, a dense band of microtubules that marks the position in the cell where cytokinesis will occur in cells that perform cytokinesis by cell plate formation.
914	phragmoplast assembly	P	The formation of a structure composed of actin, myosin, and associated proteins that will function in cytokinesis in cells that perform cytokinesis by cell plate formation. The structure usually contains antiparallel microtubules and membrane (often visible as vesicles).
915	actomyosin contractile ring assembly	P	The process of assembly of a ring composed of actin, myosin, and associated proteins that will function in cytokinesis.
916	actomyosin contractile ring contraction	P	The process of an actomyosin ring getting smaller in diameter, in the context of cytokinesis that takes place as part of a cell cycle.
917	barrier septum assembly	P	The assembly and arrangement of a septum that spans the plasma membrane interface between progeny cells following cytokinesis. The progeny cells that form a barrier septum are not able to exchange intracellular material.
918	barrier septum site selection	P	The process of marking the site where a barrier septum will form.
919	cell plate assembly	P	The process of assembly, maturation, and growth of the cell plate to the cell periphery in cells that divide by cell plate formation; often involves deposition of cell wall material in and around the phragmoplast.
920	cell separation after cytokinesis	P	The process of physically separating progeny cells after cytokinesis; this may involve enzymatic digestion of septum or cell wall components.
921	septin ring assembly	P	The aggregation, arrangement and bonding together of septins and associated proteins to form an organized structure resembling a ring at the cell cortex.
922	spindle pole	C	Either of the ends of a spindle, where spindle microtubules are organized; usually contains a microtubule organizing center and accessory molecules, spindle microtubules and astral microtubules.
923	equatorial microtubule organizing center	C	A microtubule organizing center formed by a band of gamma-tubulin that is recruited to a circumferential band of F-actin at the midpoint of a cell and which nucleates microtubules from the cell division site at the end of mitosis.
924	gamma-tubulin ring complex, centrosomal	C	A centrosome-localized multiprotein complex composed of gamma-tubulin and other non-tubulin proteins assembled into a ring structure that is thought to be the unit of nucleation at the minus end of a microtubule. Gamma-tubulin small complexes are thought to be the core repeating units of the ring.
927	gamma-tubulin small complex, centrosomal	C	A centrosomal complex usually comprising two gamma-tubulin molecules, at least two conserved non-tubulin proteins that multimerize along with additional non-tubulin proteins in animal cells into larger functional complexes. Gamma-tubulin small complexes are thought to be the repeating unit making up the core of the gamma-tubulin ring complex. An example of this structure is found in Mus musculus.
928	gamma-tubulin small complex, spindle pole body	C	A complex composed of two gamma-tubulin molecules and conserved non-tubulin proteins located in the spindle pole body and isolated by fractionation from cells. The complex, approximately 6S-9S, is analogous to the small complex in animal cells but contains fewer subunits, and is not thought to multimerize into larger functional units, like complexes in those organisms. An example of this structure is found in Saccharomyces cerevisiae.
930	gamma-tubulin complex	C	A multiprotein complex composed of gamma-tubulin and other non-tubulin proteins. Gamma-tubulin complexes are localized to microtubule organizing centers, and play an important role in the nucleation of microtubules. The number and complexity of non-tubulin proteins associated with these complexes varies between species.
931	gamma-tubulin large complex	C	A complex of gamma tubulin and associated proteins thought to be formed by multimerization of gamma-tubulin small complexes. An example of this structure is found in Schizosaccharomyces pombe.
932	P-body	C	A focus in the cytoplasm where mRNAs may become inactivated by decapping or some other mechanism. Protein and RNA localized to these foci are involved in mRNA degradation, nonsense-mediated mRNA decay (NMD), translational repression, and RNA-mediated gene silencing.
933	adventitious septum	C	A cell septum whose formation is independent of nuclear division.
934	porous cell septum	C	A septum or cross wall which does not entirely span the space between two portions of cell wall and may contain a specialized central pore structure. A porous septum allows the movement of organelles and/or cytoplasm between compartments.
935	barrier septum	C	A septum which spans a cell and does not allow exchange of organelles or cytoplasm between compartments.
936	primary cell septum	C	A cell septum that forms following nuclear division.
937	dolipore septum	C	A septum, or cross-wall, between two portions of a cell or hypha; contains a central pore around which the septum is swollen to form a barrel-shaped structure; pore is covered on each side of the septum by a septal pore cap (parenthosome).
938	GARP complex	C	A quatrefoil tethering complex required for retrograde traffic from the early endosome back to the late Golgi and biogenesis of cytoplasmic vesicles.
939	condensed chromosome inner kinetochore	C	The region of a condensed chromosome kinetochore closest to centromeric DNA; in mammals the CREST antigens (CENP proteins) are found in this layer; this layer may help define underlying centromeric chromatin structure and position of the kinetochore on the chromosome.
940	condensed chromosome outer kinetochore	C	The region of a condensed chromosome kinetochore most external to centromeric DNA; this outer region mediates kinetochore-microtubule interactions.
941	condensed nuclear chromosome inner kinetochore	C	The region of a condensed nuclear chromosome kinetochore closest to centromeric DNA; this layer may help define underlying centromeric chromatin structure and position of the kinetochore on the chromosome.
942	condensed nuclear chromosome outer kinetochore	C	The region of a condensed nuclear chromosome kinetochore most external to centromeric DNA; this outer region mediates kinetochore-microtubule interactions.
943	retrotransposon nucleocapsid	C	A complex of the retrotransposon RNA genome, reverse transcriptase, integrase, and associated molecules required for reproduction and integration of the retrotransposon into the host genome; the main structural molecule of the nucleocapsid is often a gag protein homolog.
944	base pairing with rRNA	F	Interacting selectively and non-covalently with ribosomal ribonucleic acid (rRNA) via hydrogen bonds between the bases of a gene product molecule and the bases of a target rRNA molecule.
945	base pairing with snRNA	F	Interacting selectively and non-covalently with small nuclear ribonucleic acid (snRNA) via hydrogen bonds between the bases of a gene product molecule and the bases of a target snRNA molecule.
946	base pairing with tRNA	F	Interacting selectively and non-covalently with transfer ribonucleic acid (mRNA) via hydrogen bonds between the bases of a gene product molecule and the bases of a target tRNA molecule.
947	amino acid catabolic process to alcohol via Ehrlich pathway	P	The chemical reactions and pathways involving the catabolism of amino acids to produce alcohols with one carbon less than the starting amino acid. In S. cerevisiae, this is known to occur for leucine, isoleucine, valine, methionine, phenylalanine, tyrosine, or tryptophan. Often referred to as the Ehrlich pathway, these reactions generally occur during fermentation to produce a variety of alcohols, often collectively referred to as fusel alcohols. Depending on the redox state of the cells, carboxylic acid derivatives may be produced instead of alcohols.
948	amino acid catabolic process to carboxylic acid via Ehrlich pathway	P	The chemical reactions and pathways involving the catabolism of amino acids to produce carboxylic acids with one carbon less than the starting amino acid. In S. cerevisiae, this is known to occur for leucine, isoleucine, valine, methionine, phenylalanine, tyrosine, or tryptophan. Often referred to as the Ehrlich pathway, these reactions generally occur during fermentation to produce a variety of carboxylic acids, sometimes collectively referred to as fusel acids. Depending on the redox state of the cells, alcohol derivatives may be produced instead of carboxylic acids.
949	aromatic amino acid family catabolic process to alcohol via Ehrlich pathway	P	The chemical reactions and pathways involving the catabolism of aromatic amino acids to produce aromatic alcohols with one carbon less than the starting amino acid. In S. cerevisiae, this is known to occur for leucine, isoleucine, valine, methionine, phenylalanine, tyrosine, or tryptophan. When an aromatic family amino acid, phenylalanine, tyrosine, or tryptophan, is used as the substrate, 2-phenylethanol, 4-hydroxyphenylethanol, or tryptophol, respectively, is produced. Often referred to as the Ehrlich pathway, these reactions generally occur during fermentation to produce a variety of alcohols, often collectively referred to as fusel alcohols. Depending on the redox state of the cells, carboxylic acid derivatives may be produced instead of alcohols.
950	branched-chain amino acid catabolic process to alcohol via Ehrlich pathway	P	The chemical reactions and pathways involving the catabolism of branched chain amino acids to produce branched chain alcohols with one carbon less than the starting amino acid. In S. cerevisiae, this is known to occur for leucine, isoleucine, valine, methionine, phenylalanine, tyrosine, or tryptophan. When a branched chain family amino acid, leucine, isoleucine, or valine, is used as the substrate, 3-methylbutanol, 2-methylbutanol, or 2-methylpropanol, respectively, is produced. Often referred to as the Ehrlich pathway, these reactions generally occur during fermentation to produce a variety of alcohols, often collectively referred to as fusel alcohols. Depending on the redox state of the cells, carboxylic acid derivatives may be produced instead of alcohols.
951	methionine catabolic process to 3-methylthiopropanol	P	The chemical reactions and pathways involving the catabolism of branched chain amino acids to produce branched chain alcohols with one carbon less than the starting amino acid. In S. cerevisiae, this is known to occur for leucine, isoleucine, valine, methionine, phenylalanine, tyrosine, or tryptophan. When methionine is used as the substrate, 3-methylthiopropanol is produced. Often referred to as the Ehrlich pathway, these reactions generally occur during fermentation to produce a variety of alcohols, often collectively referred to as fusel alcohols. Depending on the redox state of the cells, carboxylic acid derivatives may be produced instead of alcohols.
952	aromatic amino acid family catabolic process to carboxylic acid via Ehrlich pathway	P	The chemical reactions and pathways involving the catabolism of amino acids to produce carboxylic acids with one carbon less than the starting amino acid. In S. cerevisiae, this is known to occur for leucine, isoleucine, valine, methionine, phenylalanine, tyrosine, or tryptophan. When an aromatic family amino acid, phenylalanine, tyrosine, or tryptophan, is used as the substrate, 2-phenylethanoate, 4-hydroxyphenylethanoate, or 2-(Indol-3-yl)-ethanoate, respectively, is produced. Often referred to as the Ehrlich pathway, these reactions generally occur during fermentation to produce a variety of carboxylic acids, sometimes collectively referred to as fusel acids. Depending on the redox state of the cells, alcohol derivatives may be produced instead of carboxylic acids.
953	branched-chain amino acid catabolic process to carboxylic acid via Ehrlich pathway	P	The chemical reactions and pathways involving the catabolism of amino acids to produce carboxylic acids with one carbon less than the starting amino acid. In S. cerevisiae, this is known to occur for leucine, isoleucine, valine, methionine, phenylalanine, tyrosine, or tryptophan. When a branched chain family amino acid, leucine, isoleucine, or valine, is used as the substrate, 3-methylbutanoate, 2-methylbutanoate, or 2-methylpropanoate, respectively, is produced. Often referred to as the Ehrlich pathway, these reactions generally occur during fermentation to produce a variety of carboxylic acids, sometimes collectively referred to as fusel acids. Depending on the redox state of the cells, alcohol derivatives may be produced instead of carboxylic acids.
954	methionine catabolic process to 3-methylthiopropanoate	P	The chemical reactions and pathways involving the catabolism of amino acids to produce carboxylic acids with one carbon less than the starting amino acid. In S. cerevisiae, this is known to occur for leucine, isoleucine, valine, methionine, phenylalanine, tyrosine, or tryptophan. When methionine is used as the substrate, 3-methylthiopropanoate is produced. Often referred to as the Ehrlich pathway, these reactions generally occur during fermentation to produce a variety of carboxylic acids, sometimes collectively referred to as fusel acids. Depending on the redox state of the cells, alcohol derivatives may be produced instead of carboxylic acids.
955	amino acid catabolic process via Ehrlich pathway	P	The chemical reactions and pathways involving the catabolism of amino acids to produce alcohols or carboxylic acids containing one carbon less than the starting amino acid. In S. cerevisiae, this is known to occur for leucine, isoleucine, valine, methionine, phenylalanine, tyrosine, or tryptophan. Often referred to as the Ehrlich pathway, these reactions generally occur during fermentation to produce a variety of alcohols, often collectively referred to as fusel alcohols. Depending on the redox state of the cells, carboxylic acid derivatives, sometimes referred to as fusel acids, may be produced instead of alcohols.
956	nuclear-transcribed mRNA catabolic process	P	The chemical reactions and pathways resulting in the breakdown of nuclear-transcribed mRNAs in eukaryotic cells.
957	mitochondrial RNA catabolic process	P	The chemical reactions and pathways resulting in the breakdown of RNA transcribed from the mitochondrial genome and occurring in the mitochondrion.
958	mitochondrial mRNA catabolic process	P	The chemical reactions and pathways resulting in the breakdown of mRNA transcribed from the mitochondrial genome and occurring in the mitochondrion.
959	mitochondrial RNA metabolic process	P	The chemical reactions and pathways involving RNA transcribed from the mitochondrial genome and occurring in the mitochondrion.
960	regulation of mitochondrial RNA catabolic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving catabolism in the mitochondrion of RNA transcribed from the mitochondrial genome.
961	negative regulation of mitochondrial RNA catabolic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving catabolism in the mitochondrion of RNA transcribed from the mitochondrial genome.
962	positive regulation of mitochondrial RNA catabolic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving catabolism in the mitochondrion of RNA transcribed from the mitochondrial genome.
963	mitochondrial RNA processing	P	The conversion of a primary RNA molecule transcribed from a mitochondrial genome into one or more mature RNA molecules; occurs in the mitochondrion.
964	mitochondrial RNA 5'-end processing	P	Any process involved in forming the mature 5' end of an RNA molecule transcribed from a mitochondrial genome; occurs in the mitochondrion.
965	mitochondrial RNA 3'-end processing	P	Any process involved in forming the mature 3' end of an RNA molecule transcribed from a mitochondrial genome; occurs in the mitochondrion.
966	RNA 5'-end processing	P	Any process involved in forming the mature 5' end of an RNA molecule.
967	rRNA 5'-end processing	P	Any process involved in forming the mature 5' end of an rRNA molecule.
968	tRNA exon ligation	P	An RNA exon ligation process that rejoins two exons of a pre-tRNA which has had the intron removed.
969	tRNA exon ligation utilizing ATP as source of linkage phosphate	P	A tRNA exon ligation process in which the splice junction phosphate is derived from exogenous ATP. This type of ligation to rejoin the 5' and 3' exons of a tRNA is observed in vertebrate species.
970	tRNA exon ligation utilizing GTP as source of linkage phosphate	P	A tRNA exon ligation process in which the splice junction phosphate is derived from exogenous GTP. This type of ligation to rejoin the 5' and 3' exons of a tRNA is observed in the yeast Saccharomyces cerevisiae where the ligation reaction also produces a 2'-phosphate at the splice junction which is subsequently removed as part of the ligation process.
971	tRNA exon ligation utilizing 2',3' cyclic phosphate of 5'-exon as source of linkage phosphate	P	A tRNA exon ligation process in which the splice junction phosphate is derived from the 2',3' cyclic phosphate at the 3'-end of the 5'-exon. This type of ligation to rejoin the 5' and 3' exons of a tRNA is observed in wheat, Chlamydomonas, and vertebrate species including humans.
972	transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery	P	The chromosome organization process in which the DNA sequence containing a gene transcribed by RNA polymerase II is maintained in a specific location at the nuclear periphery. In S. cerevisiae, this process involves cis-acting DNA sequences such as the TATA box and upstream activating sequence (UAS) elements, trans-acting transcriptional activators, and also the 3'-UTR of the transcript.
973	posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery	P	The chromosome organization process in which the DNA sequence containing a gene transcribed by RNA polymerase II is maintained in a specific location at the nuclear periphery even after transcription has been repressed.
974	Prp19 complex	C	A protein complex consisting of Prp19 and associated proteins that is involved in the transition from the precatalytic spliceosome to the activated form that catalyzes step 1 of splicing, and which remains associated with the spliceosome through the second catalytic step. It is widely conserved, found in both yeast and mammals, though the exact composition varies. In S. cerevisiae, it contains Prp19p, Ntc20p, Snt309p, Isy1p, Syf2p, Cwc2p, Prp46p, Clf1p, Cef1p, and Syf1p.
975	regulatory region DNA binding	F	Interacting selectively and non-covalently with a DNA region that regulates a DNA-based process. Such processes include transcription, DNA replication, and DNA repair.
976	transcription regulatory region sequence-specific DNA binding	F	Interacting selectively and non-covalently with a specific sequence of DNA that is part of a regulatory region that controls transcription of that section of the DNA. The transcribed region might be described as a gene, cistron, or operon.
977	RNA polymerase II regulatory region sequence-specific DNA binding	F	Interacting selectively and non-covalently with a specific sequence of DNA that is part of a regulatory region that controls the transcription of a gene or cistron by RNA polymerase II.
978	RNA polymerase II core promoter proximal region sequence-specific DNA binding	F	Interacting selectively and non-covalently with a sequence of DNA that is in cis with and relatively close to a core promoter for RNA polymerase II.
979	RNA polymerase II core promoter sequence-specific DNA binding	F	Interacting selectively and non-covalently with the regulatory region composed of the transcription start site and binding sites for transcription factors of the RNA polymerase II basal transcription machinery.
980	RNA polymerase II distal enhancer sequence-specific DNA binding	F	Interacting selectively and non-covalently with a RNA polymerase II (Pol II) distal enhancer. In mammalian cells, enhancers are distal sequences that increase the utilization of some promoters, and can function in either orientation and in any location (upstream or downstream) relative to the core promoter.
981	RNA polymerase II transcription factor activity, sequence-specific DNA binding	F	Interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription by RNA polymerase II. The transcription factor may or may not also interact selectively with a protein or macromolecular complex.
982	transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding	F	Interacting selectively and non-covalently with a sequence of DNA that is in cis with and relatively close to a core promoter for RNA polymerase II (RNAP II) in order to modulate transcription by RNAP II.
983	transcription factor activity, RNA polymerase II core promoter sequence-specific	F	Interacting selectively and non-covalently with a specific DNA sequence in an RNA polymerase II (Pol II) core promoter, the region composed of the transcription start site and binding sites for transcription factors of the Pol II basal transcription machinery, in order to modulate transcription by Pol II. The transcription factor may or may not also interact selectively with a protein or macromolecular complex.
984	bacterial-type RNA polymerase regulatory region sequence-specific DNA binding	F	Interacting selectively and non-covalently with a sequence of DNA that is part of a regulatory region that controls the transcription of a gene or operon by a bacterial-type RNA polymerase.
985	bacterial-type RNA polymerase core promoter sequence-specific DNA binding	F	Interacting selectively and non-covalently with a specific DNA sequence in a bacterial-type RNA polymerase core promoter, the region composed of the transcription start site and binding sites for transcription factors of the basal transcription machinery, in order to modulate transcription. The transcription factor may or may not also interact selectively with a protein or macromolecular complex.
986	bacterial-type RNA polymerase core promoter proximal region sequence-specific DNA binding	F	Interacting selectively and non-covalently with a sequence of DNA that is in cis with and relatively close to a core promoter for a bacterial-type RNA polymerase.
987	core promoter proximal region sequence-specific DNA binding	F	Interacting selectively and non-covalently with a sequence of DNA that is in cis with and relatively close to the core promoter. The transcribed region might be described as a gene, cistron, or operon.
988	transcription factor activity, protein binding	F	Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules), in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well.
989	transcription factor activity, transcription factor binding	F	Interacting selectively and non-covalently with a specific transcription factor, which may be a single protein or a complex, in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well.
990	transcription factor activity, core RNA polymerase binding	F	Interacting selectively and non-covalently with an RNA polymerase in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well.
991	transcription factor activity, core RNA polymerase II binding	F	Interacting selectively and non-covalently with an RNA polymerase II (Pol II) complex, typically composed of twelve subunits, in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well.
992	polymerase III regulatory region sequence-specific DNA binding	F	Interacting selectively and non-covalently with a sequence of DNA that is part of a regulatory region that controls transcription by RNA polymerase III. The transcribed region might be contain a single gene or a cistron containing multiple genes.
993	RNA polymerase II core binding	F	Interacting selectively and non-covalently with RNA polymerase II core enzyme, a multisubunit eukaryotic nuclear RNA polymerase typically composed of twelve subunits.
994	RNA polymerase III core binding	F	Interacting selectively and non-covalently with RNA polymerase III core enzyme, a multisubunit eukaryotic nuclear RNA polymerase typically composed of seventeen subunits.
995	transcription factor activity, core RNA polymerase III binding	F	Interacting selectively and non-covalently with an RNA polymerase III (Pol III) complex, typically composed of seventeen subunits, in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well.
996	core DNA-dependent RNA polymerase binding promoter specificity activity	F	Interacting selectively and non-covalently with a DNA-dependent core RNA polymerase to form a holoenzyme complex and also, while present in the holoenzyme, interacting with promoter sequences in order to confer sequence specific recognition of promoter DNA sequence motifs.
997	mitochondrial RNA polymerase core promoter sequence-specific DNA binding	F	Interacting selectively and non-covalently with a sequence of DNA that is part of the core promoter for the mitochondrial RNA polymerase.
999	RNA polymerase III type 1 promoter transcriptional preinitiation complex assembly	P	The aggregation, arrangement and bonding together of proteins on a type 1 RNA polymerase III (Pol III) promoter DNA to form the transcriptional preinitiation complex (PIC), the formation of which is the first step of transcription. Type 1 promoters require TFIIIA for promoter recognition, which then recruits TFIIIC. TFIIIC in turn recruits TFIIIB, which recruits Pol III to the promoter.
1000	bacterial-type RNA polymerase core enzyme binding	F	Interacting selectively and non-covalently with the bacterial-type RNA polymerase core enzyme, typically consisting of two alpha, one beta, one beta prime, and one omega subunit.
1001	mitochondrial single-subunit type RNA polymerase binding	F	Interacting selectively and non-covalently with a single subunit mitochondrial RNA polymerase enzyme, which is composed of a single catalytic subunit similar to the RNA polymerase enzymes from phages T3, T7, and SP6.
1002	RNA polymerase III type 1 promoter sequence-specific DNA binding	F	Interacting selectively and non-covalently with a sequence of DNA that is a part of a type 1 promoter that controls transcription by RNA polymerase III. Type 1 promoters are found in 5S rRNA genes, downstream of the transcription start site within the sequence of the mature RNA, and require TFIIIA for recognition.
1003	RNA polymerase III type 2 promoter sequence-specific DNA binding	F	Interacting selectively and non-covalently with a sequence of DNA that is a part of a type 2 promoter that controls transcription by RNA polymerase III. Type 2 promoters consist of an A box and a B box downstream of the transcription start site within the sequence within the sequence of the mature RNA. Type 2 promoters are found in many tRNA genes as well as in other small RNAs.
1004	transcription factor activity, RNA polymerase III promoter sequence-specific binding, TFIIIB recruiting	F	The function of binding to a specific DNA sequence motif in an RNA polymerase III (Pol III) promoter in order to recruit the Pol III recruiting factor TFIIIB to the promoter.
1005	transcription factor activity, RNA polymerase III type 1 promoter sequence-specific binding, TFIIIB recruiting	F	The function of binding to a specific DNA sequence motif in a type 1 RNA polymerase III (Pol III) promoter in order to recruit the Pol III recruiting factor TFIIIB to the promoter. For type 1 Pol III promoters, this requires both TFIIIA and TFIIIC.
1006	RNA polymerase III type 3 promoter sequence-specific DNA binding	F	Interacting selectively and non-covalently with a sequence of DNA that is a part of a type 3 promoter that controls transcription by RNA polymerase III (Pol III). A type 3 Pol III promoter is composed of elements upstream of the transcription start site, including a TATA box. The human U6 snRNA gene has a type 3 promoter. Type 3 Pol III promoters have not been observed in S. cerevisiae.
1007	transcription factor activity, RNA polymerase III transcription factor binding	F	Interacting selectively and non-covalently with an RNA polymerase III transcription factor, which may be a single protein or a complex, in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well.
1008	transcription factor activity, RNA polymerase III type 2 promoter sequence-specific binding, TFIIIB recruiting	F	Interacting selectively and non-covalently with a specific DNA sequence motif in a type 2 RNA polymerase III (Pol III) promoter in order to recruit TFIIIB to the promoter. For type 2 Pol III promoters, this requires TFIIIC activity.
1009	transcription from RNA polymerase III type 2 promoter	P	The synthesis of RNA from a DNA template by RNA polymerase III (RNAP III), originating at a type 2 RNAP III promoter. Type 2 RNAP III promoters consist of an A box and a B box downstream of the transcription start site within the sequence of the mature RNA and the process of initiation is different than from other promoter types. Type 2 promoters are found in many tRNA genes as well as in other small RNAs.
1010	transcription factor activity, sequence-specific DNA binding transcription factor recruiting	F	The function of binding to a specific DNA sequence and recruiting another transcription factor to the DNA in order to modulate transcription. The recruited factor may bind DNA directly, or may be colocalized via protein-protein interactions.
1011	transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting	F	Interacting selectively and non-covalently with a specific DNA sequence and recruiting RNA polymerase to the DNA in order to form the preinitiation complex (PIC).
1012	RNA polymerase II regulatory region DNA binding	F	Interacting selectively and non-covalently with a DNA region that controls the transcription of a region of DNA by RNA polymerase II. Binding may occur as a sequence specific interaction or as an interaction observed only once a factor has been recruited to the DNA by other factors.
1013	RNA polymerase I regulatory region DNA binding	F	Interacting selectively and non-covalently with a DNA region that controls the transcription of a region of DNA by RNA polymerase I. Binding may occur as a sequence specific interaction or as an interaction observed only once a factor has been recruited to the DNA by other factors.
1014	snoRNA transcription from a type 2 RNA polymerase III promoter	P	The synthesis of small nucleolar RNA (snoRNA) from a DNA template by RNA polymerase III, originating at a type 2 RNA polymerase III promoter.
1015	snoRNA transcription from an RNA polymerase II promoter	P	The synthesis of small nucleolar RNA (snoRNA) from a DNA template by RNA polymerase II, originating at an RNA polymerase II promoter.
1016	RNA polymerase III regulatory region DNA binding	F	Interacting selectively and non-covalently with a DNA region that controls the transcription of a gene by RNA polymerase III. Binding may occur as a sequence specific interaction or as an interaction observed only once a factor has been recruited to the DNA by other factors.
1017	bacterial-type RNA polymerase regulatory region DNA binding	F	Interacting selectively and non-covalently with a DNA region that controls the transcription of a gene or operon by a bacterial-type RNA polymerase. Binding may occur as a sequence specific interaction or as an interaction observed only once a factor has been recruited to the DNA by other factors.
1018	mitochondrial RNA polymerase regulatory region DNA binding	F	Interacting selectively and non-covalently with a DNA region that controls the transcription of a region of DNA by mitochondrial RNA polymerase. Binding may occur as a high affinity and sequence specific interaction or as a lower affinity interaction observed once a factor has been recruited to the DNA by other factors.
1019	plastid RNA polymerase regulatory region DNA binding	F	Interacting selectively and non-covalently with a DNA region that controls the transcription of a region of DNA by a plastid RNA polymerase. Binding may occur as a sequence specific interaction or as an interaction observed only once a factor has been recruited to the DNA by other factors.
1020	RNA polymerase III type 3 promoter transcriptional preinitiation complex assembly	P	The aggregation, arrangement and bonding together of proteins on a type 1 RNA polymerase III (Pol III) promoter DNA to form the transcriptional preinitiation complex (PIC), the formation of which is the first step of transcription.
1021	RNA polymerase III type 2 promoter transcriptional preinitiation complex assembly	P	The aggregation, arrangement and bonding together of proteins on a type 2 RNA polymerase III (Pol III) promoter DNA to form the transcriptional preinitiation complex (PIC), the formation of which is the first step of transcription. Type 2 promoters require TFIIIC for promoter recognition, which then recruits TFIIIB, which in turn which recruits Pol III to the promoter.
1022	transcription initiation from RNA polymerase III type 1 promoter	P	A transcription initiation process on a type 1 RNA polymerase III (Pol III) that results in RNA synthesis by Pol III. Type 1 promoters are found in 5S rRNA genes, downstream of the transcription start site within the sequence of the mature RNA, and require TFIIIA for recognition.
1023	transcription initiation from RNA polymerase III type 2 promoter	P	A transcription initiation process on a type 2 RNA polymerase III (Pol III) that results in RNA synthesis by Pol III. Type 2 promoters consist of an A box and a B box downstream of the transcription start site within the sequence within the sequence of the mature RNA. Type 2 promoters are found in many tRNA genes as well as in other small RNAs.
1024	transcription initiation from RNA polymerase III type 3 promoter	P	A transcription initiation process on a type 3 RNA polymerase III (Pol III) that results in RNA synthesis by Pol III. A type 3 Pol III promoter is composed of elements upstream of the transcription start site, including a TATA box. The human U6 snRNA gene has a type 3 promoter. Type 3 Pol III promoters have not been observed in S. cerevisiae.
1025	RNA polymerase III transcription factor binding	F	Interacting selectively and non-covalently with an RNA polymerase III transcription factor, any protein required to initiate or regulate transcription by RNA polymerase III.
1026	TFIIIB-type transcription factor activity	F	Interacting selectively and non-covalently with an RNA polymerase III (Pol III) complex, typically composed of seventeen subunits, and with another protein, macromolecule, or complex, permitting those molecules to function in a coordinated way, Once recruited to an RNA polymerase III promoter by one or more other transcription factors, binds to DNA, recruits RNA polymerase III and facilitates the transition from the closed to the open complex.
1027	RNA polymerase III type 1 promoter TFIIIB-type transcription factor activity	F	Interacting selectively and non-covalently with an RNA polymerase III (Pol III) complex, typically composed of seventeen subunits, and with another protein, macromolecule, or complex, permitting those molecules to function in a coordinated way. Once recruited to an RNA polymerase III type 1 promoter by TFIIIA-type and TFIIIC-type factors, binds to DNA, recruits RNA polymerase III and facilitates the transition from the closed to the open complex.
1028	RNA polymerase III type 2 promoter TFIIIB-type transcription factor activity	F	Interacting selectively and non-covalently with an RNA polymerase III (Pol III) complex, typically composed of seventeen subunits, and with another protein, macromolecule, or complex, permitting those molecules to function in a coordinated way. Once recruited to an RNA polymerase III type 2 promoter by a TFIIIC-type factor, binds to DNA, recruits RNA polymerase III and facilitates the transition from the closed to the open complex.
1029	RNA polymerase III type 3 promoter TFIIIB-type transcription factor activity	F	Interacting selectively and non-covalently with an RNA polymerase III (Pol III) complex, typically composed of seventeen subunits, and with another protein, macromolecule, or complex, permitting those molecules to function in a coordinated way. Once recruited to an RNA polymerase III type 3 promoter by SNAP-type and TFIIIC-type factors, binds to DNA, recruits RNA polymerase III and facilitates the transition from the closed to the open complex.
1030	RNA polymerase III type 1 promoter DNA binding	F	Interacting selectively and non-covalently with a region of DNA that is a part of a type 1 promoter that controls transcription by RNA polymerase III. Type 1 promoters are found in 5S rRNA genes, downstream of the transcription start site within the sequence of the mature RNA, and require TFIIIA for recognition.
1031	RNA polymerase III type 2 promoter DNA binding	F	Interacting selectively and non-covalently with a region of DNA that is a part of a type 2 promoter that controls transcription by RNA polymerase III. Type 2 promoters consist of an A box and a B box downstream of the transcription start site within the sequence within the sequence of the mature RNA. Type 2 promoters are found in many tRNA genes as well as in other small RNAs.
1032	RNA polymerase III type 3 promoter DNA binding	F	Interacting selectively and non-covalently with a region of DNA that is a part of a type 3 promoter that controls transcription by RNA polymerase III. A type 3 Pol III promoter is composed of elements upstream of the transcription start site, including a TATA box. The human U6 snRNA gene has a type 3 promoter. Type 3 Pol III promoters have not been observed in S. cerevisiae.
1033	transcription factor activity, RNA polymerase III type 3 promoter TFIIIB recruiting	F	The function of binding to a specific DNA sequence motif in a type 3 RNA polymerase III (Pol III) promoter in order to recruit TFIIIB to the promoter. For type 3 Pol III promoters, this requires SNAPc activity.
1034	RNA polymerase III transcription factor activity, sequence-specific DNA binding	F	Interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription by RNA polymerase III. The transcription factor may or may not also interact selectively with a protein or macromolecular complex.
1035	transcription from RNA polymerase III type 3 promoter	P	The synthesis of RNA from a DNA template by RNA polymerase III (RNAP III), originating at a type 3 RNAP III promoter. A type 3 RNAP III promoter is composed of elements upstream of the transcription start site, including a TATA box and the process of initiation is different than from other promoter types. The human U6 snRNA gene has a type 3 promoter. Type 3 Pol III promoters have not been observed in S. cerevisiae.
1036	transcription initiation from RNA polymerase III hybrid type promoter	P	A transcription initiation process on a hybrid type RNA polymerase III (Pol III) that results in RNA synthesis by Pol III (Pol III). A hybrid Pol III promoter contains both regulatory elements both upstream and downstream of the transcription initiation site. An example gene with such a promoter is the S. cerevisiae U6 gene.
1037	RNA polymerase III hybrid type promoter DNA binding	F	Interacting selectively and non-covalently with a region of DNA that is a part of a hybrid promoter that controls transcription by RNA polymerase III (Pol III). A hybrid Pol III promoter contains both regulatory elements both upstream and downstream of the transcription initiation site. An example gene with such a promoter is the S. cerevisiae U6 gene.
1038	RNA polymerase III hybrid type promoter TFIIIB recruiting transcription factor activity	F	Once recruited to an RNA polymerase III hybrid type promoter by sequence-specific DNA binding transcription factors, direct DNA binding, or a combination of both, binds to DNA, recruits RNA polymerase III and facilitates the transition from the closed to the open complex.
1039	RNA polymerase III hybrid type promoter sequence-specific DNA binding	F	Interacting selectively and non-covalently with a sequence of DNA that is a part of a hybrid type promoter that controls transcription by RNA polymerase III (Pol III). A hybrid Pol III promoter contains both regulatory elements both upstream and downstream of the transcription initiation site. An example gene with such a promoter is the S. cerevisiae U6 gene.
1040	RNA polymerase III hybrid type promoter TFIIIB-type transcription factor activity	F	Interacting selectively and non-covalently with an RNA polymerase III (Pol III) complex, typically composed of seventeen subunits, and with another protein, macromolecule, or complex, permitting those molecules to function in a coordinated way. Once recruited to an RNA polymerase III hybrid type promoter, binds to DNA, recruits RNA polymerase III and facilitates the transition from the closed to the open complex.
1041	transcription from a RNA polymerase III hybrid type promoter	P	The synthesis of RNA from a DNA template by RNA polymerase III, originating at a hybrid type RNA polymerase III (RNAP III) promoter. A hybrid RNAP III promoter contains both regulatory elements both upstream and downstream of the transcription initiation site. An example gene with such a promoter is the S. cerevisiae U6 gene.
1042	RNA polymerase I core binding	F	Interacting selectively and non-covalently with RNA polymerase I core enzyme, a multisubunit eukaryotic nuclear RNA polymerase typically composed of seventeen subunits.
1043	RNA polymerase III hybrid type promoter transcriptional preinitiation complex assembly	P	The aggregation, arrangement and bonding together of proteins on a hybrid type RNA polymerase III (Pol III) promoter DNA to form the transcriptional preinitiation complex (PIC), the formation of which is the first step of transcription. Hybrid type promoters contain both gene-internal and upstream elements. An example of a hybrid promoter is the U6 snRNA gene.
1044	mitochondrial RNA polymerase regulatory region sequence-specific DNA binding	F	Interacting selectively and non-covalently with a specific sequence of DNA that controls the transcription of a region of DNA by mitochondrial RNA polymerase.
1045	mitochondrial RNA polymerase core promoter proximal region sequence-specific DNA binding	F	Interacting selectively and non-covalently with a sequence of DNA that is in cis with and relatively close to a core promoter for a mitochondrial RNA polymerase.
1046	core promoter sequence-specific DNA binding	F	Interacting selectively and non-covalently with a sequence of DNA that is part of a core promoter region composed of the transcription start site and binding sites for the basal transcription machinery. The transcribed region might be described as a gene, cistron, or operon.
1047	core promoter binding	F	Interacting selectively and non-covalently with the regulatory region composed of the transcription start site and binding sites for the basal transcription machinery. Binding may occur as a sequence specific interaction or as an interaction observed only once a factor has been recruited to the DNA by other factors.
1048	RNA polymerase IV core binding	F	Interacting selectively and non-covalently with RNA polymerase IV core enzyme, a multisubunit eukaryotic nuclear RNA polymerase found in plants and involved in siRNA production.
1049	RNA polymerase V core binding	F	Interacting selectively and non-covalently with RNA polymerase V core enzyme, a multisubunit eukaryotic nuclear RNA polymerase found in plants and involved in production of noncoding transcripts at target loci for silencing.
1050	single-subunit type RNA polymerase binding	F	Interacting selectively and non-covalently with a single subunit RNA polymerase enzyme, which is composed of a single catalytic subunit similar to the RNA polymerase enzymes from phages T3, T7, and SP6.
1051	plastid single-subunit type RNA polymerase binding	F	Interacting selectively and non-covalently with a single subunit plastid RNA polymerase enzyme, which is composed of a single catalytic subunit similar to the RNA polymerase enzymes from phages T3, T7, and SP6.
1052	plastid PEP RNA polymerase core enzyme binding	F	Interacting selectively and non-covalently with the bacterial-type plastid PEP RNA polymerase core enzyme, typically consisting of two alpha, one beta, one beta prime, and one double prime subunit.
1053	plastid sigma factor activity	F	Interacting selectively and non-covalently with a plastid PEP core RNA polymerase to form a holoenzyme complex and also, while present in the holoenzyme, interacting with promoter sequences in order to confer sequence specific recognition of plastid PEP core promoter DNA sequence motifs.
1054	RNA polymerase I activity	F	Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template that contains an RNA polymerase I specific promoter to direct initiation and catalyzes DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'.
1055	RNA polymerase II activity	F	Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template that contains an RNA polymerase II specific promoter to direct initiation and catalyses DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'.
1056	RNA polymerase III activity	F	Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template that contains an RNA polymerase III specific promoter to direct initiation and catalyses DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'.
1057	RNA polymerase IV activity	F	Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template that contains an RNA polymerase IV specific promoter to direct initiation and catalyses DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'.
1058	RNA polymerase V activity	F	Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template that contains an RNA polymerase V specific promoter to direct initiation and catalyses DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'.
1059	transcription from RNA polymerase IV promoter	P	The synthesis of RNA from a DNA template by RNA polymerase IV (Pol III), originating at a Pol IV-specific promoter.
1060	transcription from RNA polymerase V promoter	P	The synthesis of RNA from a DNA template by RNA polymerase V (Pol III), originating at a Pol V-specific promoter.
1061	bacterial-type RNA polymerase activity	F	Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template that contains a bacterial-type specific promoter to direct initiation and catalyses DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'.
1062	plastid PEP-A RNA polymerase activity	F	Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template that contains a plastid PEP-A RNA polymerase II specific promoter to direct initiation and catalyses DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'.
1063	plastid PEP-B RNA polymerase activity	F	Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template that contains a plastid PEP-B RNA polymerase II specific promoter to direct initiation and catalyses DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'.
1064	single subunit type RNA polymerase activity	F	Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template that contains a single-subunit-type RNA polymerase-specific promoter to direct initiation and catalyses DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'.
1065	mitochondrial single subunit type RNA polymerase activity	F	Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template that contains a single-subunit-type mitochondrial RNA polymerase-specific promoter to direct initiation and catalyses DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'.
1066	plastid single subunit type RNA polymerase activity	F	Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template that contains a single subunit type plastid RNA polymerase specific promoter to direct initiation and catalyses DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'.
1067	regulatory region nucleic acid binding	F	Interacting selectively and non-covalently with a nucleic acid region that regulates a nucleic acid-based process. Such processes include transcription, DNA replication, and DNA repair.
1068	transcription regulatory region RNA binding	F	Interacting selectively and non-covalently with a RNA region within the transcript that regulates the transcription of a region of DNA, which may be a gene, cistron, or operon.
1069	regulatory region RNA binding	F	Interacting selectively and non-covalently with a RNA region that regulates a nucleic acid-based process. Such processes include transcription, DNA replication, and DNA repair.
1070	RNA binding transcription factor activity	F	Interacting selectively and non-covalently with an RNA sequence in order to modulate transcription. The transcription factor may or may not also interact selectively with a protein or macromolecular complex.
1071	nucleic acid binding transcription factor activity	F	Interacting selectively and non-covalently with a DNA or RNA sequence in order to modulate transcription. The transcription factor may or may not also interact selectively with a protein or macromolecular complex.
1072	transcription antitermination factor activity, RNA binding	F	Binds to RNA, typically within the nascent RNA transcript, to promote readthrough of a transcription termination site and thus extending the length of the RNA transcript produced. Examples of antitermination factors which bind the nascent RNA include the lambda N protein and the HIV-1 tat protein.
1073	transcription antitermination factor activity, DNA binding	F	Binds to DNA, typically within region of the promoter and transcribed region, to promote readthrough of a transcription termination site and thus extending the length of the RNA transcript produced. Examples of antitermination factors which bind DNA include the lambda Q protein.
1074	transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding involved in preinitiation complex assembly	F	Interacting selectively and non-covalently with a sequence of DNA that is in cis with and relatively close to a core promoter for RNA polymerase II (RNAP II) in order to promote assembly of the transcriptional preinitiation complex (PIC), the formation of which is a prerequisite for transcription from an RNA polymerase II promoter.
1075	transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly	F	Interacting selectively and non-covalently with a specific DNA sequence in an RNA polymerase II (Pol II) core promoter, the region composed of the transcription start site and binding sites for transcription factors of the Pol II basal transcription machinery, in order to promote assembly of the transcriptional preinitiation complex (PIC), the formation of which is a prerequisite for transcription from an RNA polymerase II promoter.
1076	transcription factor activity, RNA polymerase II transcription factor binding	F	Interacting selectively and non-covalently with an RNA polymerase II transcription factor, which may be a single protein or a complex, in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well.
1077	transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding	F	Interacting selectively and non-covalently with a sequence of DNA that is in cis with and relatively close to a core promoter for RNA polymerase II (RNAP II) in order to activate or increase the frequency, rate or extent of transcription from the RNAP II promoter.
1078	transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding	F	Interacting selectively and non-covalently with a sequence of DNA that is in cis with and relatively close to a core promoter for RNA polymerase II (RNAP II) in order to stop, prevent, or reduce the frequency, rate or extent of transcription from an RNA polymerase II promoter.
1079	nitrogen catabolite regulation of transcription from RNA polymerase II promoter	P	A transcription regulation process in which the presence of one nitrogen source leads to the modulation of the frequency, rate, or extent of transcription, from an RNA polymerase II promoter, of specific genes involved in the metabolism of other nitrogen sources.
1080	nitrogen catabolite activation of transcription from RNA polymerase II promoter	P	A transcription regulation process in which the presence of one nitrogen source leads to an increase in the frequency, rate, or extent of transcription, from an RNA polymerase II promoter, of specific genes involved in the metabolism of other nitrogen sources.
1081	nitrogen catabolite repression of transcription from RNA polymerase II promoter	P	A transcription regulation process in which the presence of one nitrogen source leads to a decrease in the frequency, rate, or extent of transcription, from an RNA polymerase II promoter, of specific genes involved in the metabolism of other nitrogen sources.
1082	transcription factor activity, RNA polymerase I transcription factor binding	F	Interacting selectively and non-covalently with an RNA polymerase I transcription factor, which may be a single protein or a complex, in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well.
1083	transcription factor activity, RNA polymerase II basal transcription factor binding	F	Interacting selectively and non-covalently with a basal RNA polymerase II transcription factor, which may be a single protein or a complex, in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well.
1084	transcription factor activity, TFIID-class binding	F	Interacting selectively and non-covalently with a basal RNA polymerase II transcription factor of the TFIID class in order to modulate transcription. The transcription factor may or may not also interact selectively with DNA as well.
1085	RNA polymerase II transcription factor binding	F	Interacting selectively and non-covalently with an RNA polymerase II transcription factor, any protein required to initiate or regulate transcription by RNA polymerase II.
1086	transcription factor activity, TFIIA-class binding	F	Interacting selectively and non-covalently with a basal RNA polymerase II transcription factor of the TFIIA class in order to modulate transcription. The transcription factor may or may not also interact selectively with DNA as well.
1087	transcription factor activity, TFIIB-class binding	F	Interacting selectively and non-covalently with a basal RNA polymerase II transcription factor of the TFIIB class in order to modulate transcription. The transcription factor may or may not also interact selectively with DNA as well.
1088	transcription factor activity, TFIIE-class binding	F	Interacting selectively and non-covalently with a basal RNA polymerase II transcription factor of the TFIIE class in order to modulate transcription. The transcription factor may or may not also interact selectively with DNA as well.
1089	transcription factor activity, TFIIF-class transcription factor binding	F	Interacting selectively and non-covalently with a basal RNA polymerase II transcription factor of the TFIIF class in order to modulate transcription. The transcription factor may or may not also interact selectively with DNA as well.
1090	transcription factor activity, TFIIH-class binding	F	Interacting selectively and non-covalently with a basal RNA polymerase II transcription factor of the TFIIH class in order to modulate transcription. The transcription factor may or may not also interact selectively with DNA as well.
1091	RNA polymerase II basal transcription factor binding	F	Interacting selectively and non-covalently with a basal RNA polymerase II transcription factor, any of the factors involved in formation of the preinitiation complex (PIC) by RNA polymerase II and defined as a basal or general transcription factor.
1092	TFIIA-class transcription factor binding	F	Interacting selectively and non-covalently with a basal RNA polymerase II transcription factor of the TFIIA class, one of the factors involved in formation of the preinitiation complex (PIC) by RNA polymerase II and defined as a basal or general transcription factor.
1093	TFIIB-class transcription factor binding	F	Interacting selectively and non-covalently with a basal RNA polymerase II transcription factor of the TFIIB class, one of the factors involved in formation of the preinitiation complex (PIC) by RNA polymerase II and defined as a basal or general transcription factor.
1094	TFIID-class transcription factor binding	F	Interacting selectively and non-covalently with a basal RNA polymerase II transcription factor of the TFIID class, one of the factors involved in formation of the preinitiation complex (PIC) by RNA polymerase II and defined as a basal or general transcription factor.
1095	TFIIE-class transcription factor binding	F	Interacting selectively and non-covalently with a basal RNA polymerase II transcription factor of the TFIIE class, one of the factors involved in formation of the preinitiation complex (PIC) by RNA polymerase II and defined as a basal or general transcription factor.
1096	TFIIF-class transcription factor binding	F	Interacting selectively and non-covalently with a basal RNA polymerase II transcription factor of the TFIIF class, one of the factors involved in formation of the preinitiation complex (PIC) by RNA polymerase II and defined as a basal or general transcription factor.
1097	TFIIH-class transcription factor binding	F	Interacting selectively and non-covalently with a basal RNA polymerase II transcription factor of the TFIIH class, one of the factors involved in formation of the preinitiation complex (PIC) by RNA polymerase II and defined as a basal or general transcription factor.
1098	basal transcription machinery binding	F	Interacting selectively and non-covalently with the basal transcription machinery which is composed of the RNA polymerase core enzyme and the basal transcription factor(s), the minimal set of factors required for formation of the preinitiation complex (PIC) by the RNA polymerase.
1099	basal RNA polymerase II transcription machinery binding	F	Interacting selectively and non-covalently with the basal transcription machinery for RNA polymerase II which is composed of the RNA polymerase II core enzyme, a multisubunit eukaryotic nuclear RNA polymerase typically composed of twelve subunits, and the basal RNA polymerase II transcription factors, the minimal set of factors required for formation of the preinitiation complex (PIC) by the RNA polymerase.
1100	negative regulation of exit from mitosis	P	Any process involved in the inhibition of progression from anaphase/telophase (high mitotic CDK activity) to G1 (low mitotic CDK activity).
1101	response to acid chemical	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by the chemical structure of the anion portion of a dissociated acid (rather than the acid acting as a proton donor). The acid chemical may be in gaseous, liquid or solid form.
1102	RNA polymerase II activating transcription factor binding	F	Interacting selectively and non-covalently with an RNA polymerase II transcription activating factor, a protein involved in positive regulation of transcription.
1103	RNA polymerase II repressing transcription factor binding	F	Interacting selectively and non-covalently with an RNA polymerase II transcription repressing factor, a protein involved in negative regulation of transcription.
1104	RNA polymerase II transcription cofactor activity	F	Interacting selectively and non-covalently with an RNA polymerase II (RNAP II) regulatory transcription factor and also with the RNAP II basal transcription machinery in order to modulate transcription. Cofactors generally do not bind DNA, but rather mediate protein-protein interactions between regulatory transcription factors and the basal RNAP II transcription machinery.
1105	RNA polymerase II transcription coactivator activity	F	Interacting selectively and non-covalently with an RNA polymerase II (RNAP II) regulatory transcription factor and also with the RNAP II basal transcription machinery in order to increase the frequency, rate or extent of transcription. Cofactors generally do not bind DNA, but rather mediate protein-protein interactions between activating transcription factors and the basal RNAP II transcription machinery.
1106	RNA polymerase II transcription corepressor activity	F	Interacting selectively and non-covalently with an RNA polymerase II repressing transcription factor and also with the RNA polymerase II basal transcription machinery in order to stop, prevent, or reduce the frequency, rate or extent of transcription. Cofactors generally do not bind DNA, but rather mediate protein-protein interactions between repressive transcription factors and the basal transcription machinery.
1108	bacterial-type RNA polymerase holo enzyme binding	F	Interacting selectively and non-covalently with the basal transcription machinery which is composed of a bacterial-type RNA polymerase core enzyme and a sigma factor, the minimal set of factors required for formation of the preinitiation complex (PIC) by a bacterial-type RNA polymerase.
1109	promoter clearance during DNA-templated transcription	P	Any process involved in the transition from the initiation to the elongation phases of transcription by a DNA-dependent RNA polymerase, generally including a conformational change from the initiation conformation to the elongation conformation. Promoter clearance often involves breaking contact with transcription factors involved only in the initiation phase and making contacts with elongation specific factors.
1110	promoter clearance from RNA polymerase III promoter	P	Any process involved in the transition from the initiation to the elongation phases of transcription by RNA polymerase III, generally including a conformational change from the initiation conformation to the elongation conformation. Promoter clearance often involves breaking contact with transcription factors involved only in the initiation phase.
1111	promoter clearance from RNA polymerase II promoter	P	Any process involved in the transition from the initiation to the elongation phases of transcription by RNA polymerase II, generally including a conformational change from the initiation conformation to the elongation conformation. Promoter clearance often involves breaking contact with transcription factors involved only in the initiation phase and making contacts with elongation specific factors.
1112	DNA-templated transcriptional open complex formation	P	Any process involved in the melting of the DNA hybrid of the core promoter region within the transcriptional closed complex of an RNA polymerase preinitiation complex (PIC) to produce an open complex where the DNA duplex around the transcription initiation site is unwound to form the transcription bubble.
1113	transcriptional open complex formation at RNA polymerase II promoter	P	Any process involved in the melting of the DNA hybrid of the core promoter region within the transcriptional closed complex of an RNA polymerase II preinitiation complex (PIC) to produce an open complex where the DNA duplex around the transcription initiation site is unwound to form the transcription bubble.
1114	protein-DNA-RNA complex	C	A macromolecular complex containing protein, DNA, and RNA molecules.
1115	protein-DNA-RNA complex subunit organization	P	Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a protein-DNA-RNA complex.
1116	protein-DNA-RNA complex assembly	P	The aggregation, arrangement and bonding together of proteins, DNA, and RNA molecules to form a protein-DNA-RNA complex.
1117	protein-DNA-RNA complex disassembly	P	The disaggregation of a protein-DNA-RNA complex into its constituent components.
1118	transcription ternary complex disassembly	P	The disaggregation of a transcription ternary complex, composed of RNA polymerase, template DNA, and an RNA transcript, into its constituent components.
1119	protein-DNA-RNA complex remodeling	P	The acquisition, loss, or modification of macromolecules within a protein-DNA-RNA complex, resulting in the alteration of an existing complex.
1120	protein-DNA complex remodeling	P	The acquisition, loss, or modification of macromolecules within a protein-DNA complex, resulting in the alteration of an existing complex.
1121	transcription from bacterial-type RNA polymerase promoter	P	The synthesis of RNA from a DNA template by a bacterial-type RNA polymerase, originating at a bacterial-type promoter.
1122	promoter clearance from bacterial-type RNA polymerase promoter	P	Any process involved in the transition from the initiation to the elongation phase of transcription by a bacterial-type RNA polymerase, generally including a conformational change from the initiation conformation to the elongation conformation. Promoter clearance generally involves dissociation of the sigma initiation factor.
1123	transcription initiation from bacterial-type RNA polymerase promoter	P	Any process involved in the assembly of bacterial-type RNA polymerase preinitiation complex (PIC) at the core promoter region of a DNA template, resulting in the subsequent synthesis of RNA from that promoter. The initiation phase includes PIC assembly and the formation of the first few bonds in the RNA chain, including abortive initiation, which occurs when the first few nucleotides are repeatedly synthesized and then released. The initiation phase ends just before and does not include promoter clearance, or release, which is the transition between the initiation and elongation phases of transcription.
1124	transcription elongation from bacterial-type RNA polymerase promoter	P	The extension of an RNA molecule after transcription initiation and promoter clearance at a bacterial-type RNA polymerase promoter by the addition of ribonucleotides catalyzed by a bacterial-type RNA polymerase.
1125	transcription termination from bacterial-type RNA polymerase promoter	P	The process in which the synthesis of an RNA molecule by a bacterial-type RNA polymerase using a DNA template is completed.
1126	bacterial-type RNA polymerase preinitiation complex assembly	P	The aggregation, arrangement and bonding together of proteins on a bacterial-type RNA polymerase promoter DNA to form the transcriptional preinitiation complex (PIC), the formation of which is a prerequisite for transcription by RNA polymerase.
1127	transcriptional open complex formation at bacterial-type RNA polymerase promoter	P	Any process involved in the melting of the DNA hybrid of the core promoter region within a bacterial-type RNA polymerase promoter to produce an open complex where the DNA duplex around the transcription initiation site is unwound to form the transcription bubble.
1128	RNA polymerase II transcription coactivator activity involved in preinitiation complex assembly	F	Interacting selectively and non-covalently with an RNA polymerase II (RNAP II) regulatory transcription factor and also with the RNAP II basal transcription machinery in order to increase the frequency, rate or stability of the aggregation, arrangement and bonding together of proteins on RNA polymerase II promoter DNA to form the transcriptional preinitiation complex (PIC). Cofactors generally do not bind DNA, but rather mediate protein-protein interactions between activating transcription factors and the basal RNAP II transcription machinery.
1129	RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly	F	Interacting selectively and non-covalently with a member of the class of TATA-binding proteins (TBP), including any of the TBP-related factors (TRFs), to facilitate the aggregation, arrangement and bonding together of proteins on RNA polymerase II promoter DNA to form the transcriptional preinitiation complex (PIC), the formation of which is a prerequisite for transcription by RNA polymerase.
1130	bacterial-type RNA polymerase transcription factor activity, sequence-specific DNA binding	F	Interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription by bacterial-type RNA polymerase. The transcription factor may or may not also interact selectively with a protein or macromolecular complex.
1131	transcription factor activity, bacterial-type RNA polymerase core promoter proximal region sequence-specific binding	F	Interacting selectively and non-covalently with a sequence of DNA that is in cis with and relatively close to a core promoter for a bacterial-type RNA polymerase in order to modulate transcription by bacterial-type RNA polymerase. The transcription factor may or may not also interact selectively with a protein or macromolecular complex.
1132	RNA polymerase II transcription factor activity, TBP-class protein binding	F	Interacting selectively and non-covalently with a member of the class of TATA-binding proteins (TBP), including any of the TBP-related factors (TRFs), in order to modulate transcription. The transcription factor may or may not also interact selectively with DNA as well.
1133	RNA polymerase II transcription factor activity, sequence-specific transcription regulatory region DNA binding	F	Interacting selectively and non-covalently with a specific sequence of DNA that is part of a regulatory region that controls transcription of that section of the DNA by RNA polymerase II and recruiting another transcription factor to the DNA in order to modulate transcription by RNAP II.
1134	transcription factor activity, transcription factor recruiting	F	Interacting selectively and non-covalently with a specific transcription factor, which may be a single protein or a complex, and with another protein, macromolecule, or complex, recruiting that specific transcription factor to the transcription machinery complex and thus permitting those molecules to function in a coordinated way, in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well.
1135	transcription factor activity, RNA polymerase II transcription factor recruiting	F	The function of binding to an RNA polymerase II (RNAP II) transcription factor and recruiting it to the transcription machinery complex in order to modulate transcription by RNAP II.
1136	transcription factor activity, TFIIE-class transcription factor recruiting	F	Interacting selectively and non-covalently with a basal RNA polymerase II (RNAP II) transcription factor of the TFIIE-class in order to recruit it to the RNAP II preinitiation complex (PIC) in order to modulate transcription by RNAP II.
1137	transcription factor activity, TFIIF-class transcription factor recruiting	F	Interacting selectively and non-covalently with a basal RNA polymerase II (RNAP II) transcription factor of the TFIIF-class in order to recruit it to the RNAP II preinitiation complex (PIC) in order to modulate transcription by RNAP II.
1138	transcription factor activity, TFIIH-class transcription factor recruiting	F	Interacting selectively and non-covalently with a basal RNA polymerase II (RNAP II) transcription factor of the TFIIH-class in order to recruit it to the RNAP II preinitiation complex (PIC) in order to modulate transcription by RNAP II.
1139	transcription factor activity, core RNA polymerase II recruiting	F	Interacting selectively and non-covalently with an RNA polymerase II (Pol II) complex, typically composed of twelve subunits, and with another protein, macromolecule, or complex, permitting those molecules to function in a coordinated way in order to facilitate the aggregation, arrangement and bonding together of proteins on an RNA polymerase II promoter DNA to form the transcriptional preinitiation complex (PIC), the formation of which is a prerequisite for transcription by RNA polymerase.
1140	transcriptional activator activity, bacterial-type RNA polymerase core promoter proximal region sequence-specific binding	F	Interacting selectively and non-covalently with a sequence of DNA that is in cis with and relatively close to a core promoter for a bacterial-type RNA polymerase in order to increase transcription by bacterial-type RNA polymerase. The transcription factor may or may not also interact selectively with a protein or macromolecular complex.
1141	transcriptional repressor activity, bacterial-type RNA polymerase core promoter proximal region sequence-specific binding	F	Interacting selectively and non-covalently with a sequence of DNA that is in cis with and relatively close to a core promoter for a bacterial-type RNA polymerase in order to stop, prevent, or reduce the frequency, rate or extent of transcription from a bacterial-type RNA polymerase promoter.
1142	mitochondrial RNA polymerase transcription factor activity, sequence-specific DNA binding	F	Interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription by mitochondrial RNA polymerase. The transcription factor may or may not also interact selectively with a protein or macromolecular complex.
1143	mitochondrial RNA polymerase core promoter sequence-specific DNA binding transcription factor activity	F	Interacting selectively and non-covalently with a specific DNA sequence that is part of the core promoter for mitochondrial RNA polymerase in order to modulate transcription by mitochondrial RNA polymerase. The transcription factor may or may not also interact selectively with a protein or macromolecular complex.
1144	transcription factor activity, mitochondrial RNA polymerase core promoter proximal region sequence-specific binding	F	Interacting selectively and non-covalently with a sequence of DNA that is in cis with and relatively close to a core promoter for a mitochondrial RNA polymerase in order to modulate transcription by mitochondrial RNA polymerase. The transcription factor may or may not also interact selectively with a protein or macromolecular complex.
1145	mitochondrial RNA polymerase termination site sequence-specific DNA binding	F	Interacting selectively and non-covalently with a sequence of DNA that is a terminator for mitochondrial RNA polymerase.
1146	transcription factor activity, mitochondrial RNA polymerase terminator site sequence-specific binding	F	Interacting selectively and non-covalently with a sequence of DNA that is a terminator for mitochondrial RNA polymerase in order to promote transcription termination by mitochondrial RNA polymerase.
1147	transcription termination site sequence-specific DNA binding	F	Interacting selectively and non-covalently with a sequence of DNA that promotes termination by RNA polymerase. The transcribed region might be described as a gene, cistron, or operon.
1148	bacterial-type RNA polymerase termination site sequence-specific DNA binding	F	Interacting selectively and non-covalently with a sequence of DNA that is a terminator for bacterial-type RNA polymerase.
1149	transcription factor activity, bacterial-type RNA polymerase termination site sequence-specific binding	F	Interacting selectively and non-covalently with a sequence of DNA that is a termination site for bacterial-type RNA polymerase in order to promote transcription termination by bacterial-type RNA polymerase.
1150	bacterial-type RNA polymerase enhancer sequence-specific DNA binding	F	Interacting selectively and non-covalently with a sequence of DNA that is an enhancer region that helps activate transcription of a gene or operon by a bacterial-type RNA polymerase. Enhancers for sigma-54 holoenzymes are typically located 80 to 150 base pairs upstream from the transcription start site, although they can be further away or may be downstream of the promoter. Some transcription units dependent on sigma-70 holoenzymes may also include enhancer sequences.
1151	transcription factor activity, bacterial-type RNA polymerase transcription enhancer sequence-specific binding	F	Interacting selectively and non-covalently with a sequence of DNA that is a bacterial-type enhancer region in order to activate transcription by bacterial-type RNA polymerase. The transcription factor may or may not also interact selectively with a protein or macromolecular complex. Enhancers for sigma-54 holoenzymes are typically located 80 to 150 base pairs upstream from the transcription start site. Some transcription units dependent on sigma-70 holoenzymes may also include enhancer sequences.
1152	transcription factor activity, RNA polymerase III type 1 promoter sequence-specific binding, TFIIIC recruiting	F	The function of binding to a specific DNA sequence motif in a type 1 RNA polymerase III (Pol III) promoter in order to recruit the transcription factor TFIIIC to the promoter.
1153	transcription factor activity, RNA polymerase III transcription factor recruiting	F	The function of binding to an RNA polymerase III (RNAP III) transcription factor and recruiting it to the transcription machinery complex in order to modulate transcription by RNAP III.
1154	TFIIIB-class transcription factor binding	F	Interacting selectively and non-covalently with an RNA polymerase III transcription factor of the TFIIIB class, one of the factors involved in formation of the preinitiation complex (PIC) by RNA polymerase III.
1155	TFIIIA-class transcription factor binding	F	Interacting selectively and non-covalently with an RNA polymerase III transcription factor of the TFIIIA class, one of the factors involved in formation of the preinitiation complex (PIC) at type 1 promoters (5S genes) by RNA polymerase III.
1156	TFIIIC-class transcription factor binding	F	Interacting selectively and non-covalently with an RNA polymerase III transcription factor of the TFIIIC class, one of the factors involved in formation of the preinitiation complex (PIC) by RNA polymerase III.
1158	enhancer sequence-specific DNA binding	F	Interacting selectively and non-covalently with a specific sequence of DNA that is part of an enhancer, a transcription regulatory region that is somewhat distal from the core promoter and which enhances transcription from that promoter.
1159	core promoter proximal region DNA binding	F	Interacting selectively and non-covalently with a region of DNA that is in cis with and relatively close to the core promoter. The transcribed region might be described as a gene, cistron, or operon.
1160	transcription termination site DNA binding	F	Interacting selectively and non-covalently with a region of DNA that promotes termination by RNA polymerase. The transcribed region might be described as a gene, cistron, or operon.
1161	intronic transcription regulatory region sequence-specific DNA binding	F	Interacting selectively and non-covalently with an intronic DNA sequence that regulates the transcription of the transcript it is contained within.
1162	RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding	F	Interacting selectively and non-covalently with an RNA polymerase II intronic DNA sequence that regulates the transcription of the transcript it is contained within.
1163	RNA polymerase I regulatory region sequence-specific DNA binding	F	Interacting selectively and non-covalently with a specific sequence of DNA that is part of a regulatory region that controls the transcription of a gene or cistron by RNA polymerase I.
1164	RNA polymerase I CORE element sequence-specific DNA binding	F	Interacting selectively and non-covalently with the regulatory region composed of the transcription start site and binding sites for transcription factors of the RNA polymerase I transcription machinery. This site is often referred to as the CORE element. In mammalian cells, the CORE element functions in conjunction with the Upstream Control Element (UCE), while in fungi, protozoa, and plants, the CORE element functions without a UCE.
1165	RNA polymerase I upstream control element sequence-specific DNA binding	F	Interacting selectively and non-covalently with the upstream control element (UCE, or alternately referred to as the upstream element), a sequence of DNA that is in cis with and relatively close to a core promoter for RNA polymerase I.
1166	RNA polymerase I enhancer sequence-specific DNA binding	F	Interacting selectively and non-covalently with a RNA polymerase I (Pol I) enhancer. In mammalian cells, enhancers are distal sequences that increase the utilization of promoters, and can function in either orientation and in any location (upstream or downstream) relative to the core promoter.
1167	RNA polymerase I transcription factor activity, sequence-specific DNA binding	F	Interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription by RNA polymerase I. The transcription factor may or may not also interact selectively with a protein or macromolecular complex.
1168	transcription factor activity, RNA polymerase I upstream control element sequence-specific binding	F	Interacting selectively and non-covalently with the upstream control element (UCE, or alternately referred to as the upstream element, UE), a sequence of DNA that is in cis with and relatively close to a core promoter for RNA polymerase I in order to modulate transcription by RNA polymerase I.
1169	transcription factor activity, RNA polymerase I CORE element sequence-specific binding	F	Interacting selectively and non-covalently with CORE element, a regulatory region composed of the transcription start site and binding sites for transcription factors of the RNA polymerase I transcription machinery in order to modulate transcription by RNA polymerase I.
1170	transcription factor activity, RNA polymerase I enhancer sequence-specific binding	F	Interacting selectively and non-covalently with a RNA polymerase I (Pol I) enhancer in order to modulate transcription by RNA polymerase I.
1171	reverse transcription	P	A DNA synthesis process that uses RNA as the initial template for synthesis of DNA, but which also includes an RNase activity to remove the RNA strand of an RNA-DNA heteroduplex produced by the RNA-dependent synthesis step and use of the initial DNA strand as a template for DNA synthesis.
1172	transcription, RNA-templated	P	The cellular synthesis of RNA on a template of RNA.
1173	DNA-templated transcriptional start site selection	P	Any process involved in the selection of the specific location within the template strand of a DNA-dependent RNA polymerase promoter for hybridization of the cognate ribonucleotides and formation of first phosphodiester bond within the nascent transcript.
1174	transcriptional start site selection at RNA polymerase II promoter	P	Any process involved in the selection of the specific location within the template strand of an RNA polymerase II promoter for hybridization of the cognate ribonucleotides and formation of first phosphodiester bond within the nascent transcript.
1175	transcriptional start site selection at RNA polymerase III promoter	P	Any process involved in the selection of the specific location within the template strand of an RNA polymerase III promoter for hybridization of the cognate ribonucleotides and formation of first phosphodiester bond within the nascent transcript.
1176	transcriptional start site selection at bacterial-type RNA polymerase promoter	P	Any process involved in the selection of the specific location within the template strand of a bacterial-type RNA polymerase promoter for hybridization of the cognate ribonucleotides and formation of first phosphodiester bond within the nascent transcript.
1177	regulation of transcriptional open complex formation at RNA polymerase II promoter	P	Any process that modulates the rate, frequency or extent of a process involved the melting of the DNA hybrid of the core promoter region within the transcriptional closed complex of an RNA polymerase II preinitiation complex (PIC) to produce an open complex where the DNA duplex around the transcription initiation site is unwound to form the transcription bubble.
1178	regulation of transcriptional start site selection at RNA polymerase II promoter	P	Any process that modulates the rate, frequency or extent of a process involved in the selection of the specific location within the template strand of an RNA polymerase II promoter for hybridization of the cognate ribonucleotides and formation of first phosphodiester bond within the nascent transcript.
1179	RNA polymerase I transcription factor binding	F	Interacting selectively and non-covalently with an RNA polymerase I transcription factor, any protein required to initiate or regulate transcription by RNA polymerase I.
1180	transcription initiation from RNA polymerase I promoter for nuclear large rRNA transcript	P	Any process involved in the assembly of the RNA polymerase I preinitiation complex (PIC) at an polymerase I promoter for the nuclear large ribosomal RNA (rRNA) transcript, resulting in the subsequent synthesis of rRNA from that promoter. The initiation phase includes PIC assembly and the formation of the first few bonds in the RNA chain, including abortive initiation, which occurs when the first few nucleotides are repeatedly synthesized and then released. Promoter clearance, or release, is the transition between the initiation and elongation phases of transcription.
1181	transcription factor activity, core RNA polymerase I binding	F	Interacting selectively and non-covalently with an RNA polymerase I (RNAP I) complex, typically composed of fourteen subunits, in order to modulate transcription. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well.
1182	promoter clearance from RNA polymerase I promoter	P	Any process involved in the transition from the initiation to the elongation phases of transcription by RNA polymerase I, generally including a conformational change from the initiation conformation to the elongation conformation. Promoter clearance often involves breaking contact with transcription factors involved only in the initiation phase and making contacts with elongation specific factors.
1183	transcription elongation from RNA polymerase I promoter for nuclear large rRNA transcript	P	The extension of an RNA molecule after transcription initiation and promoter clearance at an RNA polymerase I promoter for the nuclear large ribosomal RNA (rRNA) transcript by the addition of ribonucleotides catalyzed by RNA polymerase I.
1184	promoter clearance from RNA polymerase I promoter for nuclear large rRNA transcript	P	Any process involved in the transition from the initiation to the elongation phases of transcription by RNA polymerase I at a promoter for the nuclear large ribosomal RNA (rRNA) transcript, generally including a conformational change from the initiation conformation to the elongation conformation. Promoter clearance often involves breaking contact with transcription factors involved only in the initiation phase and making contacts with elongation specific factors.
1185	termination of RNA polymerase I transcription from promoter for nuclear large rRNA transcript	P	The process in which the synthesis of an rRNA molecule from a promoter for the nuclear large ribosomal RNA (rRNA) transcript by RNA polymerase I using a DNA template is completed. RNAP I termination requires binding of a terminator protein so specific sequences downstream of the transcription unit.
1186	transcription factor activity, RNA polymerase I transcription factor recruiting	F	The function of binding to an RNA polymerase I (RNAP I) transcription factor and recruiting it to the transcription machinery complex in order to modulate transcription by RNAP I.
1187	transcription factor activity, RNA polymerase I CORE element binding transcription factor recruiting	F	Interacting selectively and non-covalently with the CORE element, a regulatory region composed of the transcription start site and binding sites for transcription factors of the RNA polymerase I transcription machinery and also binding to an RNA polymerase I (RNAP I) transcription factor to recruit it to the transcription machinery complex in order to modulate transcription by RNA polymerase I.
1188	RNA polymerase I transcriptional preinitiation complex assembly	P	The aggregation, arrangement and bonding together of proteins on promoter DNA to form the transcriptional preinitiation complex (PIC), the formation of which is a prerequisite for transcription from an RNA polymerase I promoter.
1189	RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript	P	The aggregation, arrangement and bonding together of proteins on CORE promoter element DNA of the nuclear large ribosomal RNA (rRNA) transcript to form a transcriptional preinitiation complex (PIC), the formation of which is a prerequisite for transcription from the large rRNA promoter, resulting in the subsequent synthesis of the large rRNA transcript.
1190	transcriptional activator activity, RNA polymerase II transcription factor binding	F	Interacting selectively and non-covalently with an RNA polymerase II transcription factor, which may be a single protein or a complex, in order to increase the frequency, rate or extent of transcription from an RNA polymerase II promoter. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well.
1191	transcriptional repressor activity, RNA polymerase II transcription factor binding	F	Interacting selectively and non-covalently with an RNA polymerase II transcription factor, which may be a single protein or a complex, in order to stop, prevent, or reduce the frequency, rate or extent of transcription from an RNA polymerase II promoter. A protein binding transcription factor may or may not also interact with the template nucleic acid (either DNA or RNA) as well.
1192	maintenance of transcriptional fidelity during DNA-templated transcription elongation	P	Suppression of the occurrence of transcriptional errors, such as substitutions and/or insertions of nucleotides that do not correctly match the template base, during the process of transcription elongation on a DNA template.
1193	maintenance of transcriptional fidelity during DNA-templated transcription elongation from RNA polymerase II promoter	P	Suppression of the occurrence of transcriptional errors, such as substitutions and/or insertions of nucleotides that do not correctly match the template base, during the process of transcription elongation from an RNA polymerase II promoter.
1194	maintenance of transcriptional fidelity during DNA-templated transcription elongation from bacterial-type RNA polymerase promoter	P	Suppression of the occurrence of transcriptional errors, such as substitutions and/or insertions of nucleotides that do not correctly match the template base, during the process of transcription elongation from a bacterial-type RNA polymerase promoter.
1195	maintenance of transcriptional fidelity during DNA-templated transcription elongation from RNA polymerase III promoter	P	Suppression of the occurrence of transcriptional errors, such as substitutions and/or insertions of nucleotides that do not correctly match the template base, during the process of transcription elongation from a RNA polymerase III promoter.
1196	regulation of mating-type specific transcription from RNA polymerase II promoter	P	Any mating-type specific process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter.
1197	positive regulation of mating-type specific transcription from RNA polymerase II promoter	P	Any mating-type specific process that activates or increases the rate of transcription from an RNA polymerase II promoter.
1198	negative regulation of mating-type specific transcription from RNA polymerase II promoter	P	Any mating-type specific process that stops, prevents or reduces the rate of transcription from an RNA polymerase II promoter.
1199	transcription factor activity, metal ion regulated sequence-specific DNA binding	F	Interacting selectively and non-covalently with a specific DNA sequence and interacting selectively and non-covalently with any metal ion(s) and responding, e.g. by conformational change, to changes in the cellular level of those metal ions, in such a way that metal ion binding regulates the activity of the transcription factor in order to modulate transcription by an RNA polymerase. Specific mechanisms include increasing or decreasing the ability of the transcription factor to interact selectively and non-covalently with a specific DNA sequence (for example S. cerevisiae Cup2p or the prokaryotic SmtB/ArsR family, changing the conformation of transcription factor bound DNA between the apo- and metal-bound forms of the transcription factor. Additional mechanisms may exist.
1200	RNA polymerase II transcription factor activity, metal ion regulated sequence-specific DNA binding	F	Interacting selectively and non-covalently with a specific DNA sequence and interacting selectively and non-covalently with any metal ion(s) and responding, e.g. by conformational change, to changes in the cellular level of those metal ions, in such a way that metal ion binding regulates the activity of the transcription factor in order to modulate transcription by RNA polymerase II. Specific mechanisms include increasing or decreasing the ability of the transcription factor to interact selectively and non-covalently with a specific DNA sequence (for example S. cerevisiae Cup2p or the prokaryotic SmtB/ArsR family, changing the conformation of transcription factor bound DNA between the apo- and metal-bound forms of the transcription factor. Additional mechanisms may exist.
1201	RNA polymerase II transcription factor activity, metal ion regulated core promoter proximal region sequence-specific binding	F	Interacting selectively and non-covalently with a specific DNA sequence that is in cis with and relatively close to a core promoter for RNA polymerase II (RNAP II) and interacting selectively and non-covalently with any metal ion(s) and responding, e.g. by conformational change, to changes in the cellular level of those metal ions, in such a way that metal ion binding regulates the activity of the transcription factor that binds the core promoter proximal region in order to modulate transcription by RNA polymerase II. Specific mechanisms include increasing or decreasing the ability of the transcription factor to interact selectively and non-covalently with a specific DNA sequence (for example S. cerevisiae Cup2p or the prokaryotic SmtB/ArsR family, changing the conformation of transcription factor bound DNA between the apo- and metal-bound forms of the transcription factor. Additional mechanisms may exist.
1202	RNA polymerase II transcription factor activity, copper ion regulated core promoter proximal region sequence-specific binding	F	Interacting selectively and non-covalently with a specific DNA sequence that is in cis with and relatively close to a core promoter for RNA polymerase II (RNAP II) and interacting selectively and non-covalently with copper(I) (Cu+) ion(s) and responding, e.g. by conformational change, to changes in the cellular level of copper(I) (Cu+), such a way that copper ion binding regulates the activity of the transcription factor, perhaps by regulating the ability to interact selectively and non-covalently with a sequence of DNA that is in cis with and relatively close to a core promoter for RNA polymerase II (RNAP II), or by regulating some other function of the transcription factor, in order to modulate transcription by RNAP II.
1203	RNA polymerase II transcription factor activity, zinc ion regulated core promoter proximal region sequence-specific DNA binding	F	Interacting selectively and non-covalently with a specific DNA sequence that is in cis with and relatively close to a core promoter for RNA polymerase II (RNAP II) and interacting selectively and non-covalently with zinc (Zn) ion(s) and responding, e.g. by conformational change, to changes in the cellular level of zinc (Zn), in such a way that zinc ion binding regulates the activity of the transcription factor, perhaps by regulating the ability to interact selectively and non-covalently with a sequence of DNA that is in cis with and relatively close to a core promoter for RNA polymerase II (RNAP II), or by regulating some other function of the transcription factor, in order to modulate transcription by RNAP II.
1204	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding	F	Interacting selectively and non-covalently with a specific bacterial-type transcription regulatory DNA sequence and interacting selectively and non-covalently with any metal ion(s) and responding, e.g. by conformational change, to changes in the cellular level of those metal ions, in such a way that metal ion binding regulates the activity of the transcription factor in order to modulate transcription by a bacterial-type RNA polymerase. Specific mechanisms include increasing or decreasing the ability of the transcription factor to interact selectively and non-covalently with a specific DNA sequence (for example S. cerevisiae Cup2p or the prokaryotic SmtB/ArsR family, changing the conformation of transcription factor bound DNA between the apo- and metal-bound forms of the transcription factor. Additional mechanisms may exist.
1205	transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding	F	Interacting selectively and non-covalently with a sequence of DNA that is in a distal enhancer region for RNA polymerase II (RNAP II) in order to activate or increase the frequency, rate or extent of transcription from the RNAP II promoter.
1206	transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding	F	Interacting selectively and non-covalently with a sequence of DNA that is in a distal enhancer region for RNA polymerase II (RNAP II) in order to stop, prevent, or reduce the frequency, rate or extent of transcription from an RNA polymerase II promoter.
1207	histone displacement	P	The removal of histones, including histone dimers, from nucleosomes within chromatin.
1208	histone H2A-H2B dimer displacement	P	The removal of a H2A-H2B histone dimer from a nucleosome within chromatin.
1209	transcriptional activator activity, metal ion regulated sequence-specific DNA binding	F	Interacting selectively and non-covalently with a specific DNA sequence and interacting selectively and non-covalently with any metal ion(s) and responding, e.g. by conformational change, to changes in the cellular level of those metal ions, in such a way that metal ion binding regulates the activity of the transcription factor in order to activate or increase the frequency, rate or extent of cellular DNA-dependent transcription by an RNA polymerase. Specific mechanisms include increasing or decreasing the ability of the transcription factor to interact selectively and non-covalently with a specific DNA sequence (for example S. cerevisiae Cup2p or the prokaryotic SmtB/ArsR family, changing the conformation of transcription factor bound DNA between the apo- and metal-bound forms of the transcription factor. Additional mechanisms may exist.
1210	transcriptional repressor activity, metal ion regulated sequence-specific DNA binding	F	Interacting selectively and non-covalently with a specific DNA sequence and interacting selectively and non-covalently with any metal ion(s) and responding, e.g. by conformational change, to changes in the cellular level of those metal ions, in such a way that metal ion binding regulates the activity of the transcription factor in order to stop, prevent, or reduce the frequency, rate or extent of cellular DNA-dependent transcription by an RNA polymerase. Specific mechanisms include increasing or decreasing the ability of the transcription factor to interact selectively and non-covalently with a specific DNA sequence (for example S. cerevisiae Cup2p or the prokaryotic SmtB/ArsR family, changing the conformation of transcription factor bound DNA between the apo- and metal-bound forms of the transcription factor. Additional mechanisms may exist.
1211	RNA polymerase II transcriptional activator activity, copper ion regulated core promoter proximal region sequence-specific binding	F	Interacting selectively and non-covalently with a sequence of DNA that is in cis with and relatively close to a core promoter for RNA polymerase II (RNAP II) and interacting selectively and non-covalently with copper(I) (Cu+) ion(s) and responding, e.g. by conformational change, to changes in the cellular level of copper(I) (Cu+), such a way that copper ion binding regulates the activity of the transcription factor in order to activate or increase the frequency, rate or extent of transcription from the RNAP II promoter.
1212	RNA polymerase II transcriptional activator activity, zinc ion regulated core promoter proximal region sequence-specific binding	F	Interacting selectively and non-covalently with a sequence of DNA that is in cis with and relatively close to a core promoter for RNA polymerase II (RNAP II) and interacting selectively and non-covalently with zinc (Zn) ion(s) and responding, e.g. by conformational change, to changes in the cellular level of zinc (Zn), such a way that copper ion binding regulates the activity of the transcription factor in order to activate or increase the frequency, rate or extent of transcription from the RNAP II promoter.
1213	RNA polymerase II transcriptional activator activity, metal ion regulated core promoter proximal region sequence-specific binding	F	Interacting selectively and non-covalently with a sequence of DNA that is in cis with and relatively close to a core promoter for RNA polymerase II (RNAP II) and interacting selectively and non-covalently with metal ion(s) and responding, e.g. by conformational change, to changes in the cellular level of metal ion, such a way that metal ion binding regulates the activity of the transcription factor in order to activate or increase the frequency, rate or extent of transcription from the RNAP II promoter.
1214	RNA polymerase II transcriptional repressor activity, metal ion regulated core promoter proximal region sequence-specific binding	F	Interacting selectively and non-covalently with a sequence of DNA that is in cis with and relatively close to a core promoter for RNA polymerase II (RNAP II) and interacting selectively and non-covalently with metal ion(s) and responding, e.g. by conformational change, to changes in the cellular level of metal ion, such a way that metal ion binding regulates the activity of the transcription factor in order to stop, prevent, or reduce the frequency, rate or extent of transcription from an RNA polymerase II promoter.
1215	bacterial-type RNA polymerase transcriptional activator activity, metal ion regulated sequence-specific DNA binding	F	Interacting selectively and non-covalently with a specific bacterial-type transcription regulatory DNA sequence and interacting selectively and non-covalently with any metal ion(s) and responding, e.g. by conformational change, to changes in the cellular level of those metal ions, in such a way that metal ion binding regulates the activity of the transcription factor in order to activate or increase the frequency, rate or extent of cellular DNA-dependent transcription by a bacterial-type RNA polymerase. Specific mechanisms include increasing or decreasing the ability of the transcription factor to interact selectively and non-covalently with a specific DNA sequence (for example S. cerevisiae Cup2p or the prokaryotic SmtB/ArsR family, changing the conformation of transcription factor bound DNA between the apo- and metal-bound forms of the transcription factor. Additional mechanisms may exist.
1216	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding	F	Interacting selectively and non-covalently with a specific DNA sequence in order to activate or increase the frequency, rate or extent of transcription by bacterial-type RNA polymerase. The transcription factor may or may not also interact selectively with a protein or macromolecular complex.
1217	bacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA binding	F	Interacting selectively and non-covalently with a specific DNA sequence in order to stop, prevent, or reduce the frequency, rate or extent of transcription by bacterial-type RNA polymerase. The transcription factor may or may not also interact selectively with a protein or macromolecular complex.
1218	bacterial-type RNA polymerase transcriptional repressor activity, metal ion regulated sequence-specific DNA binding	F	Interacting selectively and non-covalently with a specific bacterial-type transcription regulatory DNA sequence and interacting selectively and non-covalently with any metal ion(s) and responding, e.g. by conformational change, to changes in the cellular level of those metal ions, in such a way that metal ion binding regulates the activity of the transcription factor in order to stop, prevent, or reduce the frequency, rate or extent of cellular DNA-dependent transcription by a bacterial-type RNA polymerase. Specific mechanisms include increasing or decreasing the ability of the transcription factor to interact selectively and non-covalently with a specific DNA sequence (for example S. cerevisiae Cup2p or the prokaryotic SmtB/ArsR family, changing the conformation of transcription factor bound DNA between the apo- and metal-bound forms of the transcription factor. Additional mechanisms may exist.
1219	bacterial-type RNA polymerase transcriptional repressor activity, copper ion regulated sequence-specific DNA binding	F	Interacting selectively and non-covalently with a specific bacterial-type transcription regulatory DNA sequence and interacting selectively and non-covalently with copper(I) (Cu+) ion(s) and responding, e.g. by conformational change, to changes in the cellular level of copper(I) (Cu+), in such a way that copper ion binding regulates the activity of the transcription factor in order to stop, prevent, or reduce the frequency, rate or extent of cellular DNA-dependent transcription by a bacterial-type RNA polymerase.
1220	bacterial-type RNA polymerase transcriptional repressor activity, cadmium ion regulated sequence-specific DNA binding	F	Interacting selectively and non-covalently with a specific bacterial-type transcription regulatory DNA sequence and interacting selectively and non-covalently with cadmium (Cd) ion(s) and responding, e.g. by conformational change, to changes in the cellular level of cadmium (Cd), in such a way that cadmium (Cd) ion binding regulates the activity of the transcription factor in order to stop, prevent, or reduce the frequency, rate or extent of cellular DNA-dependent transcription by a bacterial-type RNA polymerase.
1221	transcription cofactor binding	F	Interacting selectively and non-covalently with a transcription cofactor, any protein involved in regulation of transcription via protein-protein interactions with transcription factors and other transcription regulatory proteins. Cofactors do not bind DNA directly, but rather mediate protein-protein interactions between regulatory transcription factors and the basal transcription machinery.
1222	transcription corepressor binding	F	Interacting selectively and non-covalently with a transcription corepressor, any protein involved in negative regulation of transcription via protein-protein interactions with transcription factors and other proteins that negatively regulate transcription. Transcription corepressors do not bind DNA directly, but rather mediate protein-protein interactions between repressing transcription factors and the basal transcription machinery.
1223	transcription coactivator binding	F	Interacting selectively and non-covalently with a transcription coactivator, any protein involved in positive regulation of transcription via protein-protein interactions with transcription factors and other proteins that positively regulate transcription. Transcription coactivators do not bind DNA directly, but rather mediate protein-protein interactions between activating transcription factors and the basal transcription machinery.
1224	RNA polymerase II transcription cofactor binding	F	Interacting selectively and non-covalently with a transcription cofactor for RNA polymerase II, any protein involved in regulation of transcription via protein-protein interactions with RNA polymerase II transcription factors and other transcription regulatory proteins. Cofactors do not bind DNA directly, but rather mediate protein-protein interactions between regulatory transcription factors and the basal transcription machinery of RNA polymerase II.
1225	RNA polymerase II transcription coactivator binding	F	Interacting selectively and non-covalently with an RNA polymerase II transcription coactivator, any protein involved in positive regulation of transcription of RNA polymerase II via protein-protein interactions with transcription factors and other proteins that positively regulate transcription. Transcription coactivators do not bind DNA directly, but rather mediate protein-protein interactions between activating transcription factors and the basal transcription machinery of RNA polymerase II.
1226	RNA polymerase II transcription corepressor binding	F	Interacting selectively and non-covalently with an RNA polymerase II transcription corepressor, any protein involved in negative regulation of transcription by RNA polymerase II via protein-protein interactions with transcription factors and other proteins that negatively regulate transcription. Transcription corepressors do not bind DNA directly, but rather mediate protein-protein interactions between repressing transcription factors and the basal transcription machinery of RNA polymerase II.
1227	transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding	F	Interacting selectively and non-covalently with a sequence of DNA that is in the regulatory region for RNA polymerase II (RNAP II) in order to stop, prevent, or reduce the frequency, rate or extent of transcription from an RNA polymerase II promoter.
1228	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding	F	Interacting selectively and non-covalently with a sequence of DNA that is in the transcription regulatory region for RNA polymerase II (RNAP II) in order to activate or increase the frequency, rate or extent of transcription from the RNAP II promoter.
1300	chronological cell aging	P	The process associated with progression of the cell from its inception to the end of its lifespan that occurs when the cell is in a non-dividing, or quiescent, state.
1301	progressive alteration of chromatin involved in cell aging	P	Any chromatin organization process that occurs during the lifespan of the cell that results in changes in chromatin structure. Such changes may lead to gene dysregulation and ultimately to a loss in cell homeostasis, bringing about an aging phenotype.
1302	replicative cell aging	P	The process associated with progression of the cell from its inception to the end of its lifespan that occurs as the cell continues cycles of growth and division.
1303	nucleolar fragmentation involved in replicative aging	P	A nucleolar fragmentation process that gives rise to multiple rounded structures and that occurs in conjunction with increasing age in dividing cells.
1304	progressive alteration of chromatin involved in replicative cell aging	P	A process that results in changes in chromatin structure contributing to replicative cell aging.
1305	progressive alteration of chromatin involved in chronological cell aging	P	A process that results in changes in chromatin structure contributing to chronological cell aging, occurring in non-dividing cells.
1306	age-dependent response to oxidative stress	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, where the change varies according to the age of the cell or organism.
1307	extrachromosomal circular DNA accumulation involved in replicative cell aging	P	Increase in abundance of circular DNA molecules in dividing cells as they age. These molecules originate in the chromosome but are excised and circularized, often by intramolecular homologous recombination between direct tandem repeats, and then replicated independently of chromosomal replication.
1308	negative regulation of chromatin silencing involved in replicative cell aging	P	The process, which occurs as a dividing cell ages, leading to expression of genes that are typically not expressed due to silencing by regulatory proteins.
1310	extrachromosomal rDNA circle accumulation involved in replicative cell aging	P	Increase in abundance of circular DNA molecules containing ribosomal DNA repeats in dividing cells as they age. These molecules originate in the chromosome but are excised and circularized, often by intramolecular homologous recombination between direct tandem repeats, and then replicated independently of chromosomal replication.
1311	formation of extrachromosomal circular rDNA by homologous recombination involved in replicative cell aging	P	Excision from the chromosome and circularization of DNA molecules encoding ribosomal RNA in dividing cells as they age.
1312	replication of extrachromosomal rDNA circles involved in replicative cell aging	P	Replication of rDNA following its excision from the chromosome of dividing cells as they age. Extrachromosomal rDNA forms a circle that contains at least one autonomously replicating sequence (ARS), which supports replication independent of chromosomal replication.
1313	formation of extrachromosomal circular DNA involved in replicative cell aging	P	Excision from the chromosome and circularization of a region of chromosomal DNA, generally, but not always, via homologous recombination between direct tandem repeats, in dividing cells as they age.
1314	replication of extrachromosomal circular DNA involved in replicative cell aging	P	Replication of circular DNA following excision from the chromosome of dividing cells as they age; replication of extrachromosomal circular DNA generally occurs independently of chromosomal replication.
1315	age-dependent response to reactive oxygen species	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of reactive oxygen species, where the change varies according to the age of the cell or organism.
1316	age-dependent response to reactive oxygen species involved in replicative cell aging	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) occurring during the process of replicative cell aging as a result of reactive oxygen species, where the change varies according to the age of the cell or organism.
1317	accumulation of oxidatively modified proteins involved in replicative cell aging	P	Accumulation of proteins that have undergone reactions with reactive oxygen species in aging dividing cells and exhibit modifications such as increased protein carbonyl content, oxidized methionine, protein hydrophobicity, and cross-linking.
1318	formation of oxidatively modified proteins involved in replicative cell aging	P	Chemical reaction, between proteins and reactive oxygen species, that occurs in dividing cells as they age and leads to a variety of changes in the affected proteins, including increases in protein carbonyl content, oxidized methionine, protein hydrophobicity, and cross-linking.
1319	inheritance of oxidatively modified proteins involved in replicative cell aging	P	A protein localization process in which progeny cells acquire, or are barred from acquiring, proteins that have been altered by reaction with reactive oxygen species in dividing aging cells.
1320	age-dependent response to reactive oxygen species involved in chronological cell aging	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) occurring in non-dividing cells as they age as a result of reactive oxygen species, where the change varies according to the age of the cell or organism.
1321	age-dependent general metabolic decline involved in replicative cell aging	P	A process of general metabolic decline that arises in dividing cells as they age, and alters cellular metabolism to cause a decline in cell function.
1322	age-dependent response to oxidative stress involved in replicative cell aging	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) occurring in dividing cells as they age as a result of oxidative stress, where the change varies according to the age of the cell or organism.
1323	age-dependent general metabolic decline involved in chronological cell aging	P	A process of general metabolic decline that arises in non-dividing cells as they age, and alters cellular metabolism to cause a decline in cell function.
1324	age-dependent response to oxidative stress involved in chronological cell aging	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) occurring in non-dividing cells as they age as a result of oxidative stress, where the change varies according to the age of the cell or organism.
1325	formation of extrachromosomal circular DNA	P	Excision from the chromosome and circularization of a region of chromosomal DNA, generally, but not always, via homologous recombination between direct tandem repeats.
1326	replication of extrachromosomal circular DNA	P	Replication of circular DNA following excision from the chromosome; replication of extrachromosomal circular DNA generally occurs independently of chromosomal replication.
1400	mating projection base	C	The region where the mating projection meets the bulk of the cell, in unicellular fungi exposed to mating pheromone.
1401	mitochondrial sorting and assembly machinery complex	C	A large complex of the mitochondrial outer membrane that mediates sorting of some imported proteins to the outer membrane and their assembly in the membrane; functions after import of incoming proteins by the mitochondrial outer membrane translocase complex.
1402	signal transduction involved in filamentous growth	P	Relaying of environmental signals promoting filamentous growth.
1403	invasive growth in response to glucose limitation	P	A growth pattern exhibited by budding haploid cells under certain growth conditions, in which cells retain the typical axial budding pattern of haploids, but become elongated and fail to separate after division; during growth on a solid substrate, this results in penetration of cells into the agar medium. An example of this process is found in Saccharomyces cerevisiae.
1405	presequence translocase-associated import motor	C	Protein complex located on the matrix side of the mitochondrial inner membrane and associated with the presequence translocase complex; hydrolyzes ATP to provide the force to drive import of proteins into the mitochondrial matrix.
1406	glycerophosphodiester transmembrane transporter activity	F	Enables the transfer of glycerophosphodiesters from one side of a membrane to the other. Glycerophosphodiesters are small molecules composed of glycerol-3-phosphate and an alcohol, for example, glycerophosphoinositol.
1407	glycerophosphodiester transport	P	The directed movement of glycerophosphodiesters into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Glycerophosphodiesters are small molecules composed of glycerol-3-phosphate and an alcohol, for example, glycerophosphoinositol.
1408	guanine nucleotide transport	P	The directed movement of guanine nucleotides, GTP, GDP, and/or GMP, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
1409	guanine nucleotide transmembrane transporter activity	F	Catalysis of the transfer of guanine nucleotides (GMP, GDP, and GTP) from one side of the membrane to the other.
1410	chlamydospore formation	P	The process whose specific outcome is the progression of the chlamydospore over time, from its formation to the mature structure. A chlamydospores is a mitotic (asexual) one-celled spore, produced primarily for survival, not dispersal, originating endogenously and singly within part of a pre-existing cell and possessing an inner secondary and often thickened cell wall. An example of this is found in Candida albicans.
1411	hyphal tip	C	The end, or tip, of a fungal hypha, where polarized growth occurs during hyphal elongation.
1501	skeletal system development	P	The process whose specific outcome is the progression of the skeleton over time, from its formation to the mature structure. The skeleton is the bony framework of the body in vertebrates (endoskeleton) or the hard outer envelope of insects (exoskeleton or dermoskeleton).
1502	cartilage condensation	P	The condensation of mesenchymal cells that have been committed to differentiate into chondrocytes.
1503	ossification	P	The formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone or a bony substance.
1504	neurotransmitter uptake	P	The directed movement of neurotransmitters into neurons or glial cells. This process leads to inactivation and recycling of neurotransmitters.
1505	regulation of neurotransmitter levels	P	Any process that modulates levels of neurotransmitter.
1507	acetylcholine catabolic process in synaptic cleft	P	The chemical reactions and pathways resulting in the breakdown of acetylcholine that occurs in the synaptic cleft during synaptic transmission.
1508	action potential	P	A process in which membrane potential cycles through a depolarizing spike, triggered in response to depolarization above some threshold, followed by repolarization. This cycle is driven by the flow of ions through various voltage gated channels with different thresholds and ion specificities.
1510	RNA methylation	P	Posttranscriptional addition of a methyl group to either a nucleotide or 2'-O ribose in a polyribonucleotide. Usually uses S-adenosylmethionine as a cofactor.
1512	dihydronicotinamide riboside quinone reductase activity	F	Catalysis of the reaction: 1-(beta-D-ribofuranosyl)-1,4-dihydronicotinamide + a quinone = 1-(beta-D-ribofuranosyl)nicotinamide + a hydroquinone.
1514	selenocysteine incorporation	P	The incorporation of selenocysteine into a peptide; uses a special tRNA that recognizes the UGA codon as selenocysteine, rather than as a termination codon. Selenocysteine is synthesized from serine before its incorporation; it is not a posttranslational modification of peptidyl-cysteine.
1515	opioid peptide activity	F	Naturally occurring peptide that is an opioid (any non-alkaloid having an opiate-like effect that can be reversed by naloxone or other recognized morphine antagonist). These include Leu- and Met-enkephalin, dynorphin and neoendorphin, alpha, beta, gamma and delta endorphins formed from beta-lipotropin, various pronase-resistant peptides such as beta casamorphin, and other peptides whose opiate-like action seems to be indirect.
1516	prostaglandin biosynthetic process	P	The chemical reactions and pathways resulting in the formation of prostaglandins, any of a group of biologically active metabolites which contain a cyclopentane ring.
1517	N-acetylglucosamine 6-O-sulfotransferase activity	F	Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + N-acetyl-D-glucosamine = adenosine 3',5'-bisphosphate + N-acetyl-D-glucosamine 6-sulfate.
1518	voltage-gated sodium channel complex	C	A sodium channel in a cell membrane whose opening is governed by the membrane potential.
1519	peptide amidation	P	The posttranslational conversion of C-terminal glycine-extended peptides to C-terminal alpha-amidated peptides. Occurs to over half of all peptide hormones to give bioactive peptides. This is a two step process catalyzed by a peptidyl-glycine alpha-hydroxylating monooxygenase and a peptidyl-alpha-hydroxyglycine alpha-amidating lyase. In some organisms, this process is catalyzed by two separate enzymes, whereas in higher organisms, one polypeptide catalyzes both reactions.
1520	outer dense fiber	C	A supramolecular fiber found in the flagella of mammalian sperm that surrounds the nine microtubule doublets. These dense fibers are stiff and noncontractile. In human, they consist of about 10 major and at least 15 minor proteins, where all major proteins are ODF1, ODF2 or ODF2-related proteins.
1522	pseudouridine synthesis	P	The intramolecular conversion of uridine to pseudouridine within an RNA molecule. This posttranscriptional base modification occurs in tRNA, rRNA, and snRNAs.
1523	retinoid metabolic process	P	The chemical reactions and pathways involving retinoids, any member of a class of isoprenoids that contain or are derived from four prenyl groups linked head-to-tail. Retinoids include retinol and retinal and structurally similar natural derivatives or synthetic compounds, but need not have vitamin A activity.
1525	angiogenesis	P	Blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels.
1527	microfibril	C	Extracellular matrix components occurring independently or along with elastin. Thought to have force-bearing functions in tendon. In addition to fibrillins, microfibrils may contain other associated proteins.
1530	lipopolysaccharide binding	F	Interacting selectively and non-covalently with lipopolysaccharide.
1531	interleukin-21 receptor binding	F	Interacting selectively and non-covalently with the interleukin-21 receptor.
1532	interleukin-21 receptor activity	F	Combining with interleukin-21 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
1533	cornified envelope	C	A type of plasma membrane that has been modified through addition of distinct intracellular and extracellular components, including ceramide, found in cornifying epithelial cells (corneocytes).
1534	radial spoke	C	Protein complex that links the outer microtubule doublet of the ciliary or flagellum axoneme with the sheath that surrounds the central pair of microtubules. Composed of a stalk that attaches to each doublet microtubule and a globular structure (spoke head) that projects toward the central pair of microtubules.
1535	radial spoke head	C	Protein complex forming part of eukaryotic flagellar apparatus.
1536	radial spoke stalk	C	Globular portion of the radial spoke that projects towards the central pair of microtubules.
1537	N-acetylgalactosamine 4-O-sulfotransferase activity	F	Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + N-acetyl-D-galactosamine = adenosine 3',5'-bisphosphate + N-acetyl-D-galactosamine 4-sulfate.
1539	cilium or flagellum-dependent cell motility	P	Cell motility due to movement of eukaryotic cilia or bacterial-type flagella or archaeal-type flagella.
1540	beta-amyloid binding	F	Interacting selectively and non-covalently with beta-amyloid peptide/protein and/or its precursor.
1541	ovarian follicle development	P	The process whose specific outcome is the progression of the ovarian follicle over time, from its formation to the mature structure.
1542	ovulation from ovarian follicle	P	The process leading to the rupture of the follicle, releasing the centrally located oocyte into the oviduct. An example of this is found in Mus musculus.
1543	ovarian follicle rupture	P	Disruption of theca cell layer releasing follicular fluid and/or the oocyte.
1544	initiation of primordial ovarian follicle growth	P	Increase in size of primordial follicles including proliferation and shape changes of granulosa and/or theca cells until oocyte is surrounded by one layer of cuboidal shaped granulosa cells (primary follicle).
1545	primary ovarian follicle growth	P	Increase in size of primary follicles including oocyte growth and granulosa and/or theca cell proliferation until more than one layer of granulosa cells is present (preantral follicle).
1546	preantral ovarian follicle growth	P	Increase in size of follicles surrounded by two or more layers of granulosa cells up to the onset of antrum formation.
1547	antral ovarian follicle growth	P	Increase in size of antral follicles due to cell proliferation and/or growth of the antral cavity.
1548	follicular fluid formation in ovarian follicle antrum	P	The menstrual cycle process that results in the formation of one central cavity separating the oocyte/cumulus complex from mural granulosa and theca cells during the various stages of oogenesis.
1549	cumulus cell differentiation	P	The process in which a subpopulation of granulosa cells surrounding the oocyte acquires the specialized features of an ovarian cumulus cell.
1550	ovarian cumulus expansion	P	Increase in size of the cumulus surrounding the oocyte including change in morphology due to proliferation and dispersion of cumulus cells.
1551	ovarian follicle endowment	P	Association of oocytes with supporting epithelial granulosa cells to form primordial follicles.
1552	ovarian follicle atresia	P	A periodic process in which immature ovarian follicles degenerate and are subsequently re-absorbed.
1553	luteinization	P	The set of processes resulting in differentiation of theca and granulosa cells into luteal cells and in the formation of a corpus luteum after ovulation.
1554	luteolysis	P	The lysis or structural demise of the corpus luteum. During normal luteolysis, two closely related events occur. First, there is loss of the capacity to synthesize and secrete progesterone (functional luteolysis) followed by loss of the cells that comprise the corpus luteum (structural luteolysis). Preventing luteolysis is crucial to maintain pregnancy.
1555	oocyte growth	P	The developmental growth process in which an oocyte irreversibly increases in size over time by accretion and biosynthetic production of matter similar to that already present.
1556	oocyte maturation	P	A developmental process, independent of morphogenetic (shape) change, that is required for an oocyte to attain its fully functional state. Oocyte maturation commences after reinitiation of meiosis commonly starting with germinal vesicle breakdown, and continues up to the second meiotic arrest prior to fertilization.
1558	regulation of cell growth	P	Any process that modulates the frequency, rate, extent or direction of cell growth.
1559	regulation of cell growth by detection of nuclear:cytoplasmic ratio	P	Any process in which the size of the nucleus with respect to the cytoplasm modulates the frequency, rate or extent of cell growth, the irreversible increase in size of a cell over time.
1560	regulation of cell growth by extracellular stimulus	P	Any process in which external signals modulate the frequency, rate or extent of cell growth, the irreversible increase in size of a cell over time.
1561	fatty acid alpha-oxidation	P	A metabolic pathway by which 3-methyl branched fatty acids are degraded. These compounds are not degraded by the normal peroxisomal beta-oxidation pathway, because the 3-methyl blocks the dehydrogenation of the hydroxyl group by hydroxyacyl-CoA dehydrogenase. The 3-methyl branched fatty acid is converted in several steps to pristenic acid, which can then feed into the beta-oxidative pathway.
1562	response to protozoan	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a protozoan.
1563	detection of protozoan	P	The series of events in which a stimulus from a protozoan is received and converted into a molecular signal.
1565	phorbol ester receptor activity	F	Combining with a phorbol ester and transmitting the signal to initiate a change in cell activity.
1566	non-kinase phorbol ester receptor activity	F	Combining with a phorbol ester and transmitting the signal by a mechanism independent of kinase activity.
1567	cholesterol 25-hydroxylase activity	F	Catalysis of the reaction: AH(2) + cholesterol + O(2) = 25-hydroxycholesterol + A + H(2)O.
1568	blood vessel development	P	The process whose specific outcome is the progression of a blood vessel over time, from its formation to the mature structure. The blood vessel is the vasculature carrying blood.
1569	branching involved in blood vessel morphogenesis	P	The process of coordinated growth and sprouting of blood vessels giving rise to the organized vascular system.
1570	vasculogenesis	P	The differentiation of endothelial cells from progenitor cells during blood vessel development, and the de novo formation of blood vessels and tubes.
1571	non-tyrosine kinase fibroblast growth factor receptor activity	F	Combining with fibroblast growth factor (FGF) and transmitting the signal from one side of the membrane to the other by a mechanism independent of tyrosine kinase activity.
1572	lactosylceramide biosynthetic process	P	The chemical reactions and pathways resulting in the formation of lactosylceramides, Gal-beta-(1->4)-Glc-beta(1->1') ceramides, any compound formed by the replacement of the glycosidic C1 hydroxyl group of lactose by a ceramide group. They are the precursors of both gangliosides and globosides.
1573	ganglioside metabolic process	P	The chemical reactions and pathways involving ceramide oligosaccharides carrying in addition to other sugar residues, one or more sialic acid residues.
1574	ganglioside biosynthetic process	P	The chemical reactions and pathways resulting in the formation of ceramide oligosaccharides carrying in addition to other sugar residues, one or more sialic acid residues.
1575	globoside metabolic process	P	The chemical reactions and pathways involving globosides, globotetraosylceramides, ceramides containing a core structure of GalNAc-beta-(1->3)-Gal-alpha-(1->4)-Glc(I). Globosides are the major neutral glycosphingolipid in normal kidneys and erythrocytes.
1576	globoside biosynthetic process	P	The chemical reactions and pathways resulting in the formation of a ceramide with a core structure of GalNAc-beta-(1->3)-Gal-alpha-(1->4)-Glc(I).
1578	microtubule bundle formation	P	A process that results in a parallel arrangement of microtubules.
1579	medium-chain fatty acid transport	P	The directed movement of medium-chain fatty acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A medium-chain fatty acid is a fatty acid with a chain length of between C6 and C12.
1580	detection of chemical stimulus involved in sensory perception of bitter taste	P	The series of events required for a bitter taste stimulus to be received and converted to a molecular signal.
1581	detection of chemical stimulus involved in sensory perception of sour taste	P	The series of events required for a sour taste stimulus to be received and converted to a molecular signal.
1582	detection of chemical stimulus involved in sensory perception of sweet taste	P	The series of events required for a sweet taste stimulus to be received and converted to a molecular signal.
1583	detection of chemical stimulus involved in sensory perception of salty taste	P	The series of events required for a salty taste stimulus to be received and converted to a molecular signal.
1586	Gi/o-coupled serotonin receptor activity	F	Combining with serotonin and transmitting the signal across the membrane by activation of the Gi/o subunit of an associated cytoplasmic heterotrimeric G protein complex. The Gi/o subunit subsequently inhibits adenylate cyclase and results in a decrease in cyclic AMP (cAMP) levels.
1587	Gq/11-coupled serotonin receptor activity	F	Combining with serotonin and transmitting the signal across the membrane by activation of the Gq/11 subunit of an associated cytoplasmic heterotrimeric G protein complex. The Gq/11 subunit subsequently activates phospholipase C and results in an increase in inositol triphosphate (IP3) levels.
1588	dopamine neurotransmitter receptor activity, coupled via Gs	F	Combining with the neurotransmitter dopamine and activating adenylate cyclase via coupling to Gs to initiate a change in cell activity.
1591	dopamine neurotransmitter receptor activity, coupled via Gi/Go	F	Combining with the neurotransmitter dopamine and activating adenylate cyclase via coupling to Gi/Go to initiate a change in cell activity.
1594	trace-amine receptor activity	F	Combining with a trace amine to initiate a change in cell activity. Trace amines are biogenic amines that are synthesized from aromatic amino acids and are substrates for monoamine oxidase, and are therefore detectable only at trace levels in mammals.
1595	angiotensin receptor activity	F	Combining with angiotensin to initiate a change in cell activity.
1596	angiotensin type I receptor activity	F	An angiotensin receptor activity that acts via Gq-mediated activation of phospholipase C followed by phosphoinositide hydrolysis and Ca2+ signaling, and may act via additional signaling mechanisms.
1601	peptide YY receptor activity	F	Combining with gut peptide YY to initiate a change in cell activity.
1602	pancreatic polypeptide receptor activity	F	Combining with pancreatic polypeptide PP to initiate a change in cell activity.
1604	urotensin II receptor activity	F	Combining with urotensin II to initiate a change in cell activity.
1605	adrenomedullin receptor activity	F	Combining with adrenomedullin to initiate a change in cell activity.
1607	neuromedin U receptor activity	F	Combining with neuromedin U to initiate a change in cell activity.
1608	G-protein coupled nucleotide receptor activity	F	Combining with a nucleotide and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.
1609	G-protein coupled adenosine receptor activity	F	Combining with adenosine and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.
1614	purinergic nucleotide receptor activity	F	Combining with a purine nucleotide and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
1616	growth hormone secretagogue receptor activity	F	Combining with ghrelin to initiate a change in cell activity.
1618	virus receptor activity	F	Combining with a virus component and mediating entry of the virus into the cell.
1621	ADP receptor activity	F	Combining with ADP and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
1626	nociceptin receptor activity	F	Combining with the peptide nociceptin, and transmitting the signal across the membrane by activating an associated G-protein.
1631	cysteinyl leukotriene receptor activity	F	Combining with a cysteinyl leukotriene to initiate a change in cell activity. Cysteinyl leukotrienes are leukotrienes that contain a peptide group based on cysteine.
1632	leukotriene B4 receptor activity	F	Combining with leukotriene B4, LTB4, to initiate a change in cell activity. Leukotriene B4 is also known as (6Z, 8E, 10E, 14Z)-(5S, 12R)-5,12-dihydroxyicosa-6,8,10,14-tetraen-1-oate.
1634	pituitary adenylate cyclase-activating polypeptide receptor activity	F	A G-protein coupled receptor that interacts with pituitary adenylate cyclase-activating polypeptide.
1635	calcitonin gene-related peptide receptor activity	F	Combining with a calcitonin gene-related polypeptide (CGRP) to initiate a change in cell activity.
1637	G-protein coupled chemoattractant receptor activity	F	Combining with a chemoattractant and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.
1639	PLC activating G-protein coupled glutamate receptor activity	F	A G-protein coupled receptor that binds glutamate and is linked to the inositol 1,4,5-trisphosphate/calcium signaling system.
1640	adenylate cyclase inhibiting G-protein coupled glutamate receptor activity	F	Combining with glutamate and transmitting the signal across the membrane by activating the alpha-subunit of an associated heterotrimeric G-protein complex to inhibit downstream adenylate cyclase activity.
1641	group II metabotropic glutamate receptor activity	F	A G-protein coupled receptor that is activated by trans-1-aminocyclopentane-1,3-dicarboxylic acid (t-ACPD) and inhibits adenylate cyclase activity.
1642	group III metabotropic glutamate receptor activity	F	A G-protein coupled receptor that is activated by L-AP-4 and inhibits adenylate cyclase activity.
1646	cAMP receptor activity	F	Combining with cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
1647	G-protein coupled cytokinin receptor activity	F	Combining with cytokinin and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.
1648	proteinase activated receptor activity	F	A G-protein coupled peptide receptor activity that is initiated by cleavage of the N terminus of the receptor by a serine protease, resulting in the generation of a new tethered ligand that interacts with the receptor.
1649	osteoblast differentiation	P	The process whereby a relatively unspecialized cell acquires the specialized features of an osteoblast, a mesodermal or neural crest cell that gives rise to bone.
1650	fibrillar center	C	A structure found most metazoan nucleoli, but not usually found in lower eukaryotes; surrounded by the dense fibrillar component; the zone of transcription from multiple copies of the pre-rRNA genes is in the border region between these two structures.
1651	dense fibrillar component	C	A structure found in the nucleolus, which contains newly synthesized preribosomal RNA (pre-rRNA) and a collection of proteins.
1652	granular component	C	A structure found in the nucleolus, which contains nearly completed preribosomal particles destined for the cytoplasm.
1653	peptide receptor activity	F	Combining with an extracellular or intracellular peptide to initiate a change in cell activity.
1654	eye development	P	The process whose specific outcome is the progression of the eye over time, from its formation to the mature structure. The eye is the organ of sight.
1655	urogenital system development	P	The process whose specific outcome is the progression of the urogenital system over time, from its formation to the mature structure.
1656	metanephros development	P	The process whose specific outcome is the progression of the metanephros over time, from its formation to the mature structure. In mammals, the metanephros is the excretory organ of the fetus, which develops into the mature kidney and is formed from the rear portion of the nephrogenic cord. The metanephros is an endocrine and metabolic organ that filters the blood and excretes the end products of body metabolism in the form of urine.
1657	ureteric bud development	P	The process whose specific outcome is the progression of the ureteric bud over time, from its formation to the mature structure.
1658	branching involved in ureteric bud morphogenesis	P	The process in which the branching structure of the ureteric bud is generated and organized. The ureteric bud is an epithelial tube that grows out from the metanephric duct. The bud elongates and branches to give rise to the ureter and kidney collecting tubules.
1659	temperature homeostasis	P	A homeostatic process in which an organism modulates its internal body temperature.
1660	fever generation	P	The heat generation process that results in a rise in body temperature above the normal, often as a response to infection.
1661	conditioned taste aversion	P	A conditioned aversion to a specific chemical compound as a result of that compound being coupled with a noxious stimulus.
1662	behavioral fear response	P	An acute behavioral change resulting from a perceived external threat.
1664	G-protein coupled receptor binding	F	Interacting selectively and non-covalently with a G-protein coupled receptor.
1665	alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity	F	Catalysis of the reaction: CMP-N-acetylneuraminate + glycano-(1->3)-(N-acetyl-alpha-D-galactosaminyl)-glycoprotein = CMP + glycano-[(2->6)-alpha-N-acetylneuraminyl]-(N-acetyl-D-galactosaminyl)-glycoprotein.
1666	response to hypoxia	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level.
1667	ameboidal-type cell migration	P	Cell migration that is accomplished by extension and retraction of a pseudopodium.
1669	acrosomal vesicle	C	A structure in the head of a spermatozoon that contains acid hydrolases, and is concerned with the breakdown of the outer membrane of the ovum during fertilization. It lies just beneath the plasma membrane and is derived from the lysosome.
1671	ATPase activator activity	F	Binds to and increases the ATP hydrolysis activity of an ATPase.
1672	regulation of chromatin assembly or disassembly	P	Any process that modulates the frequency, rate or extent of chromatin assembly or disassembly.
1673	male germ cell nucleus	C	The nucleus of a male germ cell, a reproductive cell in males.
1674	female germ cell nucleus	C	The nucleus of the female germ cell, a reproductive cell in females.
1675	acrosome assembly	P	The formation of the acrosome from the spermatid Golgi.
1676	long-chain fatty acid metabolic process	P	The chemical reactions and pathways involving long-chain fatty acids, A long-chain fatty acid is a fatty acid with a chain length between C13 and C22.
1677	formation of translation initiation ternary complex	P	Formation of a complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2 (either eIF2 in eukaryotes, or IF2 in prokaryotes). In prokaryotes, fMet-tRNA (initiator) is used rather than Met-tRNA (initiator).
1678	cellular glucose homeostasis	P	A cellular homeostatic process involved in the maintenance of an internal steady state of glucose within a cell or between a cell and its external environment.
1680	tRNA 3'-terminal CCA addition	P	Post-transcriptional addition of the terminal 3' CCA sequence to a tRNA which does not encode this sequence within the primary transcript. CCA addition proceeds by the sequential addition of CTP, CTP, and then ATP to the 3' end of the tRNA, yielding a diphosphate with each nucleotide addition.
1681	sialate O-acetylesterase activity	F	Catalysis of the reaction: N-acetyl-O-acetylneuraminate (free or glycosidically bound) + H2O = N-acetylneuraminate + acetate.
1682	tRNA 5'-leader removal	P	Generation of the mature 5'-end of the tRNA, usually via an endonucleolytic cleavage by RNase P.
1691	pseudophosphatase activity	F	Maintains the phosphorylation state of certain molecules by associating with them and preventing them from associating with active phosphatases, and thus inhibiting the enzyme activity without interacting with the enzyme. Often pertains to proteins belonging to dual-specificity phosphatase family but lacking critical active site residues.
1692	histamine metabolic process	P	The chemical reactions and pathways involving histamine, a physiologically active amine, found in plant and animal tissue and released from mast cells as part of an allergic reaction in humans.
1694	histamine biosynthetic process	P	The chemical reactions and pathways resulting in the formation of histamine, a physiologically active amine, found in plant and animal tissue and released from mast cells as part of an allergic reaction in humans.
1695	histamine catabolic process	P	The chemical reactions and pathways resulting in the breakdown of histamine, a physiologically active amine, found in plant and animal tissue and released from mast cells as part of an allergic reaction in humans.
1696	gastric acid secretion	P	The regulated release of gastric acid (hydrochloric acid) by parietal or oxyntic cells during digestion.
1697	histamine-induced gastric acid secretion	P	The regulated release of gastric acid induced by the interaction of histamine with H2 type receptor receptors with subsequent activation of adenylate cyclase and elevation of intracellular cyclic AMP.
1698	gastrin-induced gastric acid secretion	P	The regulated release of gastric acid induced by the interaction of gastrin with its receptor.
1699	acetylcholine-induced gastric acid secretion	P	The regulated release of gastric acid by parietal cells in response to acetylcholine.
1700	embryonic development via the syncytial blastoderm	P	The process whose specific outcome is the progression of the embryo over time, from zygote formation through syncytial blastoderm to the hatching of the first instar larva. An example of this process is found in Drosophila melanogaster.
1701	in utero embryonic development	P	The process whose specific outcome is the progression of the embryo in the uterus over time, from formation of the zygote in the oviduct, to birth. An example of this process is found in Mus musculus.
1702	gastrulation with mouth forming second	P	A gastrulation process in which the initial invagination becomes the anus and the mouth forms second.
1703	gastrulation with mouth forming first	P	A gastrulation process in which the initial invagination becomes the mouth and the anus forms second.
1704	formation of primary germ layer	P	The formation of the ectoderm, mesoderm and endoderm during gastrulation.
1705	ectoderm formation	P	The formation of ectoderm during gastrulation.
1706	endoderm formation	P	The formation of the endoderm during gastrulation.
1707	mesoderm formation	P	The process that gives rise to the mesoderm. This process pertains to the initial formation of the structure from unspecified parts.
1708	cell fate specification	P	The process involved in the specification of cell identity. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment.
1709	cell fate determination	P	A process involved in cell fate commitment. Once determination has taken place, a cell becomes committed to differentiate down a particular pathway regardless of its environment.
1710	mesodermal cell fate commitment	P	The cell differentiation process that results in commitment of a cell to become part of the mesoderm.
1711	endodermal cell fate commitment	P	The cell differentiation process that results in commitment of a cell to become part of the endoderm.
1712	ectodermal cell fate commitment	P	The cell differentiation process that results in commitment of a cell to become part of the ectoderm.
1713	ectodermal cell fate determination	P	The cell fate determination process that results in a cell becoming capable of differentiating autonomously into an ectoderm cell regardless of its environment; upon determination, the cell fate cannot be reversed.
1714	endodermal cell fate specification	P	The cell fate determination process that results in a cell becoming capable of differentiating autonomously into an endoderm cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.
1715	ectodermal cell fate specification	P	The cell fate determination process that results in a cell becoming becomes capable of differentiating autonomously into an ectoderm cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.
1716	L-amino-acid oxidase activity	F	Catalysis of the reaction: a L-amino acid + H2O + O2 = a 2-oxo acid + NH3 + hydrogen peroxide.
1717	conversion of seryl-tRNAsec to selenocys-tRNAsec	P	The modification process that results in the conversion of serine, carried by a specialized tRNA(ser) (which can read a UGA anticodon), to selenocysteine.
1720	conversion of lysyl-tRNA to pyrrolysyl-tRNA	P	The modification process that results in the conversion of lysine, carried by a specialized lysine-accepting tRNA (possessing a CUA anticodon), to pyrrolysine (a lysine with an amide linkage to a (4R,5R)-4-substituted pyrroline-5-carboxylate).
1725	stress fiber	C	A contractile actin filament bundle that consists of short actin filaments with alternating polarity, cross-linked by alpha-actinin and possibly other actin bundling proteins, and with myosin present in a periodic distribution along the fiber.
1726	ruffle	C	Projection at the leading edge of a crawling cell; the protrusions are supported by a microfilament meshwork.
1727	lipid kinase activity	F	Catalysis of the phosphorylation of a simple or complex lipid.
1729	ceramide kinase activity	F	Catalysis of the reaction: ATP + ceramide = ADP + ceramide-1-phosphate.
1730	2'-5'-oligoadenylate synthetase activity	F	Catalysis of the reaction: ATP = pppA(2'p5'A)n oligomers. This reaction requires the binding of double-stranded RNA.
1731	formation of translation preinitiation complex	P	The joining of the small ribosomal subunit, ternary complex, and mRNA.
1732	formation of cytoplasmic translation initiation complex	P	Joining of the large subunit, with release of IF2/eIF2 and IF3/eIF3. This leaves the functional ribosome at the AUG, with the methionyl/formyl-methionyl-tRNA positioned at the P site.
1733	galactosylceramide sulfotransferase activity	F	Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + a galactosylceramide = adenosine 3',5'-bisphosphate + a galactosylceramidesulfate.
1734	mRNA (N6-adenosine)-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + RRACH = S-adenosyl-L-homocysteine + RRm6ACH; R is a purine, and H is C, A, or U.
1735	prenylcysteine oxidase activity	F	Catalysis of the reaction: S-prenyl-L-cysteine + O2 + H2O = a prenal + L-cysteine + H2O2.
1736	establishment of planar polarity	P	Coordinated organization of groups of cells in the plane of an epithelium, such that they all orient to similar coordinates.
1737	establishment of imaginal disc-derived wing hair orientation	P	Orientation of hairs in the imaginal disc-derived wing along a proximal-distal axis, such that each cell of the wing produces one wing hair which points in a distal direction.
1738	morphogenesis of a polarized epithelium	P	The morphogenetic process in which the anatomical structures of a polarized epithelium are generated and organized. A polarized epithelium is an epithelium where the epithelial sheet is oriented with respect to the planar axis.
1739	sex chromatin	C	Chromatin that is part of a sex chromosome.
1740	Barr body	C	A structure found in a female mammalian cell containing an unpaired X chromosome that has become densely heterochromatic, silenced and localized at the nuclear periphery.
1741	XY body	C	A structure found in a male mammalian spermatocyte containing an unpaired X chromosome that has become densely heterochromatic, silenced and localized at the nuclear periphery.
1742	oenocyte differentiation	P	The process in which a relatively unspecialized cell acquires the specialized features of an oenocyte. Oenocytes are large secretory cells found in clusters underlying the epidermis of larval abdominal segments.
1743	optic placode formation	P	The initial developmental process that will lead to the formation of an eye.
1744	optic lobe placode formation	P	Establishment of the optic placode, a thickened area of densely packed ectoderm cells directly overlying the optic vesicle in the early embryo. In Drosophila, for example, the placode appears in the dorsolateral region of the head in late stage 11 embryos and is the precursor to the larval visual system.
1745	compound eye morphogenesis	P	The morphogenetic process in which the anatomical structures of the compound eye are generated and organized. The adult compound eye is a precise assembly of 700-800 ommatidia. Each ommatidium is composed of 20 cells, identified by cell type and position. An example of compound eye morphogenesis is found in Drosophila melanogaster.
1746	Bolwig's organ morphogenesis	P	The morphogenetic process in which the anatomical structures of the larval eye in Drosophila are generated and organized. The larval eye in Drosophila is a relatively simple sensory system composed of Bolwig's organs: two clusters, each composed of 12 photoreceptor cells from which axons extend in a single fascicle to the brain.
1748	optic lobe placode development	P	The process whose specific outcome is the progression of the optic placode over time, from its formation to the mature structure. During embryonic stage 12 the placode starts to invaginate, forming a pouch. Cells that will form Bolwig's organ segregate from the ventral lip of this pouch, remaining in the head epidermis. The remainder of the invagination loses contact with the outer surface and becomes the optic lobe. An example of this process is found in Drosophila melanogaster.
1750	photoreceptor outer segment	C	The outer segment of a vertebrate photoreceptor that contains discs of photoreceptive membranes.
1751	compound eye photoreceptor cell differentiation	P	The process in which a relatively unspecialized cell acquires the specialized features of an eye photoreceptor cell.
1752	compound eye photoreceptor fate commitment	P	The process in which the developmental fate of a cell becomes restricted such that it will develop into a compound eye photoreceptor cell. A photoreceptor cell is a cell that responds to incident electromagnetic radiation. Different classes of photoreceptor have different spectral sensitivities and express different photosensitive pigments.
1754	eye photoreceptor cell differentiation	P	The process in which a relatively unspecialized cell acquires the specialized features of a photoreceptor cell, as found in the eye, the primary visual organ of most organisms.
1755	neural crest cell migration	P	The characteristic movement of cells from the dorsal ridge of the neural tube to a variety of locations in a vertebrate embryo.
1756	somitogenesis	P	The formation of mesodermal clusters that are arranged segmentally along the anterior posterior axis of an embryo.
1757	somite specification	P	The process in which individual somites establish identity during embryogenesis.
1758	retinal dehydrogenase activity	F	Catalysis of the reaction: retinal + NAD+ + H2O = retinoate + NADH. Acts on both 11-trans and 13-cis forms of retinal.
1759	organ induction	P	The interaction of two or more cells or tissues that causes them to change their fates and specify the development of an organ.
1760	aminocarboxymuconate-semialdehyde decarboxylase activity	F	Catalysis of the reaction: 2-amino-3-carboxymuconate 6-semialdehyde + H(+) = 2-aminomuconate 6-semialdehyde + CO(2).
1761	beta-alanine transmembrane transporter activity	F	Enables the transfer of beta-alanine from one side of a membrane to the other. Beta-alanine is 3-aminopropanoic acid.
1762	beta-alanine transport	P	The directed movement of beta-alanine, 3-aminopropanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
1763	morphogenesis of a branching structure	P	The process in which the anatomical structures of branches are generated and organized. A branch is a division or offshoot from a main stem. Examples in animals would include blood vessels, nerves, lymphatics and other endothelial or epithelial tubes.
1764	neuron migration	P	The characteristic movement of an immature neuron from germinal zones to specific positions where they will reside as they mature.
1765	membrane raft assembly	P	The aggregation, arrangement and bonding together of a set of components to form a membrane raft, a small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalizes cellular processes.
1766	membrane raft polarization	P	The clustering and aggregation of membrane rafts at a single cellular pole during activation of particular cell types, such as lymphocytes.
1767	establishment of lymphocyte polarity	P	The directed orientation of lymphocyte signaling molecules and associated membrane rafts towards a chemokine gradient or a contact point with an appropriate activating cell.
1768	establishment of T cell polarity	P	The directed orientation of T cell signaling molecules and associated membrane rafts towards a chemokine gradient or a contact point with antigen presenting cell.
1769	establishment of B cell polarity	P	The directed orientation of B cell signaling molecules and associated membrane rafts towards a chemokine gradient of a contact point with an antigen displaying cell.
1770	establishment of natural killer cell polarity	P	The directed orientation of natural killer cell signaling molecules and associated membrane rafts towards a chemokine gradient or a contact point with a cell displaying natural killer cell activating ligands.
1771	immunological synapse formation	P	The formation of an area of close contact between a lymphocyte (T-, B-, or natural killer cell) and a target cell through the clustering of particular signaling and adhesion molecules and their associated membrane rafts on both the lymphocyte and target cell, which facilitates activation of the lymphocyte, transfer of membrane from the target cell to the lymphocyte, and in some situations killing of the target cell through release of secretory granules and/or death-pathway ligand-receptor interaction.
1772	immunological synapse	C	An area of close contact between a lymphocyte (T-, B-, or natural killer cell) and a target cell formed through the clustering of particular signaling and adhesion molecules and their associated membrane rafts on both the lymphocyte and the target cell and facilitating activation of the lymphocyte, transfer of membrane from the target cell to the lymphocyte, and in some situations killing of the target cell through release of secretory granules and/or death-pathway ligand-receptor interaction.
1773	myeloid dendritic cell activation	P	The change in morphology and behavior of a dendritic cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor.
1774	microglial cell activation	P	The change in morphology and behavior of a microglial cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor.
1775	cell activation	P	A change in the morphology or behavior of a cell resulting from exposure to an activating factor such as a cellular or soluble ligand.
1776	leukocyte homeostasis	P	The process of regulating the proliferation and elimination of cells of the immune system such that the total number of cells of a particular cell type within a whole or part of an organism is stable over time in the absence of an outside stimulus.
1777	T cell homeostatic proliferation	P	The non-specific expansion of T cell populations within a whole or part of an organism to reach to a total number of T cells which will then remain stable over time in the absence of an external stimulus.
1778	plasma membrane repair	P	The resealing of a cell plasma membrane after cellular wounding due to, for instance, mechanical stress.
1779	natural killer cell differentiation	P	The process in which a relatively unspecialized cell acquires the specialized features of a natural killer cell.
1780	neutrophil homeostasis	P	The process of regulating the proliferation and elimination of neutrophils such that the total number of neutrophils within a whole or part of an organism is stable over time in the absence of an outside stimulus.
1781	neutrophil apoptotic process	P	Any apoptotic process in a neutrophil, any of the immature or mature forms of a granular leukocyte that in its mature form has a nucleus with three to five lobes connected by slender threads of chromatin, and cytoplasm containing fine inconspicuous granules and stainable by neutral dyes.
1782	B cell homeostasis	P	The process of regulating the proliferation and elimination of B cells such that the total number of B cells within a whole or part of an organism is stable over time in the absence of an outside stimulus.
1783	B cell apoptotic process	P	Any apoptotic process in a B cell, a lymphocyte of B lineage with the phenotype CD19-positive and capable of B cell mediated immunity.
1784	phosphotyrosine binding	F	Interacting selectively and non-covalently with a phosphorylated tyrosine residue within a protein.
1785	prostaglandin J receptor activity	F	Combining with prostaglandin J (PGJ(2)), a metabolite of prostaglandin D (PGD(2)) to initiate a change in cell activity.
1786	phosphatidylserine binding	F	Interacting selectively and non-covalently with phosphatidylserine, a class of glycophospholipids in which a phosphatidyl group is esterified to the hydroxyl group of L-serine.
1787	natural killer cell proliferation	P	The expansion of a natural killer cell population by cell division.
1788	antibody-dependent cellular cytotoxicity	P	Cytolysis of target cells by natural killer cells, eosinophils, neutrophils, monocytes, or macrophages following engagement of antibodies bound to the target cells by Fc receptors on the effector cells.
1789	G-protein coupled receptor signaling pathway, coupled to S1P second messenger	P	The series of molecular signals generated as a consequence of an adrenergic receptor binding to its physiological ligand, where the pathway proceeds with activation of sphingosine kinase and a subsequent increase in cellular levels of sphingosine-1-phosphate (S1P).
1790	polymeric immunoglobulin binding	F	Interacting selectively and non-covalently with a J-chain-containing polymeric immunoglobulin of the IgA or IgM isotypes.
1791	IgM binding	F	Interacting selectively and non-covalently with an immunoglobulin of the IgM isotype.
1792	polymeric immunoglobulin receptor activity	F	Combining with a J-chain-containing polymeric immunoglobulin of the IgA or IgM isotypes via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
1793	IgM receptor activity	F	Combining with an immunoglobulin of the IgM isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
1794	type IIa hypersensitivity	P	An inflammatory response resulting in cell death mediated by activation of the classical complement pathway or induction of effector cell phagocytosis or cytolysis mechanisms via complement or Fc receptors following the binding of antibodies to cell surface antigens on a target cell.
1795	type IIb hypersensitivity	P	An inflammatory response resulting in cell death or dysfunction mediated by the direct binding of antibody to cellular receptors.
1796	regulation of type IIa hypersensitivity	P	Any process that modulates the frequency, rate, or extent of type IIa hypersensitivity, a type of inflammatory response.
1797	negative regulation of type IIa hypersensitivity	P	Any process that stops, prevents, or reduces the rate of type IIa hypersensitivity, a type of inflammatory response.
1798	positive regulation of type IIa hypersensitivity	P	Any process that activates or increases the frequency, rate or extent of type IIa hypersensitivity, a type of inflammatory response.
1799	regulation of type IIb hypersensitivity	P	Any process that modulates the frequency, rate, or extent of type IIb hypersensitivity, a type of inflammatory response.
1800	negative regulation of type IIb hypersensitivity	P	Any process that stops, prevents, or reduces the rate of type IIb hypersensitivity, a type of inflammatory response.
1801	positive regulation of type IIb hypersensitivity	P	Any process that activates or increases the frequency, rate or extent of type IIb hypersensitivity, a type of inflammatory response.
1802	type III hypersensitivity	P	An inflammatory response resulting from recognition of immune complexes via complement or Fc receptors on effector cells leading to activation of neutrophils and other leukocytes and damage to bystander tissue.
1803	regulation of type III hypersensitivity	P	Any process that modulates the frequency, rate, or extent of type III hypersensitivity, a type of inflammatory response.
1804	negative regulation of type III hypersensitivity	P	Any process that stops, prevents, or reduces the rate of type III hypersensitivity, a type of inflammatory response.
1805	positive regulation of type III hypersensitivity	P	Any process that activates or increases the frequency, rate or extent of type III hypersensitivity, a type of inflammatory response.
1806	type IV hypersensitivity	P	An inflammatory response driven by T cell recognition of processed soluble or cell-associated antigens leading to cytokine release and leukocyte activation.
1807	regulation of type IV hypersensitivity	P	Any process that modulates the frequency, rate, or extent of type IV hypersensitivity, a type of inflammatory response.
1808	negative regulation of type IV hypersensitivity	P	Any process that stops, prevents, or reduces the rate of type IV hypersensitivity, a type of inflammatory response.
1809	positive regulation of type IV hypersensitivity	P	Any process that activates or increases the frequency, rate or extent of type IV hypersensitivity, a type of inflammatory response.
1810	regulation of type I hypersensitivity	P	Any process that modulates the frequency, rate, or extent of type I hypersensitivity, a type of inflammatory response.
1811	negative regulation of type I hypersensitivity	P	Any process that stops, prevents, or reduces the rate of type I hypersensitivity, a type of inflammatory response.
1812	positive regulation of type I hypersensitivity	P	Any process that activates or increases the frequency, rate or extent of type I hypersensitivity, a type of inflammatory response.
1813	regulation of antibody-dependent cellular cytotoxicity	P	Any process that modulates the frequency, rate, or extent of antibody-dependent cellular cytotoxicity.
1814	negative regulation of antibody-dependent cellular cytotoxicity	P	Any process that stops, prevents, or reduces the rate of antibody-dependent cellular cytotoxicity.
1815	positive regulation of antibody-dependent cellular cytotoxicity	P	Any process that activates or increases the frequency, rate or extent of antibody-dependent cellular cytotoxicity.
1816	cytokine production	P	The appearance of a cytokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
1817	regulation of cytokine production	P	Any process that modulates the frequency, rate, or extent of production of a cytokine.
1818	negative regulation of cytokine production	P	Any process that stops, prevents, or reduces the rate of production of a cytokine.
1819	positive regulation of cytokine production	P	Any process that activates or increases the frequency, rate or extent of production of a cytokine.
1820	serotonin secretion	P	The regulated release of serotonin by a cell. Serotonin (5-hydroxytryptamine, or 5-HT) is a monoamine synthesised in serotonergic neurons in the central nervous system, enterochromaffin cells in the gastrointestinal tract and some immune system cells.
1821	histamine secretion	P	The regulated release of histamine by a cell or tissue. It is formed by decarboxylation of histidine and it acts through receptors in smooth muscle and in secretory systems.
1822	kidney development	P	The process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure. The kidney is an organ that filters the blood and/or excretes the end products of body metabolism in the form of urine.
1823	mesonephros development	P	The process whose specific outcome is the progression of the mesonephros over time, from its formation to the mature structure. In mammals, the mesonephros is the second of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the mesonephros will form the mature kidney.
1824	blastocyst development	P	The process whose specific outcome is the progression of the blastocyst over time, from its formation to the mature structure. The mammalian blastocyst is a hollow ball of cells containing two cell types, the inner cell mass and the trophectoderm.
1825	blastocyst formation	P	The initial formation of a blastocyst from a solid ball of cells known as a morula.
1826	inner cell mass cell differentiation	P	The process in which a relatively unspecialized cell acquires specialized features of an inner cell mass cell.
1827	inner cell mass cell fate commitment	P	The cell fate commitment of precursor cells that will become inner cell mass cells.
1828	inner cell mass cellular morphogenesis	P	The morphogenesis of cells in the inner cell mass.
1829	trophectodermal cell differentiation	P	The process in which a relatively unspecialized cell acquires the specialized features of a trophectoderm cell.
1830	trophectodermal cell fate commitment	P	The cell fate commitment of precursor cells that will become trophectoderm cells.
1831	trophectodermal cellular morphogenesis	P	The morphogenesis of trophectoderm cells.
1832	blastocyst growth	P	An increase in size of a blastocyst due to expansion of the blastocoelic cavity cell shape changes and cell proliferation.
1833	inner cell mass cell proliferation	P	The proliferation of cells in the inner cell mass.
1834	trophectodermal cell proliferation	P	The proliferation of cells in the trophectoderm.
1835	blastocyst hatching	P	The hatching of the cellular blastocyst from the zona pellucida.
1836	release of cytochrome c from mitochondria	P	The process that results in the movement of cytochrome c from the mitochondrial intermembrane space into the cytosol, which is part of the apoptotic signaling pathway and leads to caspase activation.
1837	epithelial to mesenchymal transition	P	A transition where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell.
1838	embryonic epithelial tube formation	P	The morphogenesis of an embryonic epithelium into a tube-shaped structure.
1839	neural plate morphogenesis	P	The process in which the anatomical structures of the neural plate are generated and organized. The neural plate is a specialized region of columnar epithelial cells in the dorsal ectoderm that will give rise to nervous system tissue.
1840	neural plate development	P	The process whose specific outcome is the progression of the neural plate over time, from its formation to the mature structure. The neural plate is a flat, thickened layer of ectodermal cells. The underlying dorsal mesoderm signals the ectodermal cells above it to elongate into columnar neural plate cells. The neural plate subsequently develops into the neural tube, which gives rise to the central nervous system.
1841	neural tube formation	P	The formation of a tube from the flat layer of ectodermal cells known as the neural plate. This will give rise to the central nervous system.
1842	neural fold formation	P	The process in which the neural fold is formed. The edges of the neural plate thicken and move up to form a U-shaped structure called the neural groove.
1843	neural tube closure	P	The last step in the formation of the neural tube, where the paired neural folds are brought together and fuse at the dorsal midline.
1844	protein insertion into mitochondrial membrane involved in apoptotic signaling pathway	P	The process in which a protein is incorporated into a mitochondrial membrane as the initial phase of the mitochondrial membrane permeabilization that takes place in the apoptotic signaling pathway.
1845	phagolysosome assembly	P	The process that results in the fusion of a phagosome, a vesicle formed by phagocytosis, with a lysosome.
1846	opsonin binding	F	Interacting selectively and non-covalently with an opsonin, such as a complement component or antibody, deposited on the surface of a bacteria, virus, immune complex, or other particulate material.
1847	opsonin receptor activity	F	Combining with an opsonin and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
1848	complement binding	F	Interacting selectively and non-covalently with any component or product of the complement cascade.
1849	complement component C1q binding	F	Interacting selectively and non-covalently with the C1q component of the classical complement cascade.
1850	complement component C3a binding	F	Interacting selectively and non-covalently with the C3a product of the complement cascade.
1851	complement component C3b binding	F	Interacting selectively and non-covalently with the C3b product of the complement cascade.
1852	complement component iC3b binding	F	Interacting selectively and non-covalently with the iC3b product of the complement cascade.
1853	complement component C3dg binding	F	Interacting selectively and non-covalently with the C3dg product of the complement cascade.
1854	complement component C3d binding	F	Interacting selectively and non-covalently with the C3d product of the complement cascade.
1855	complement component C4b binding	F	Interacting selectively and non-covalently with the C4b product of the classical complement cascade.
1856	complement component C5a binding	F	Interacting selectively and non-covalently with the C5a product of the complement cascade.
1857	complement component C1q receptor activity	F	Combining with the C1q component of the classical complement cascade and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
1858	complement component iC3b receptor activity	F	Combining with the iC3b product of the complement cascade and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
1859	complement component C3dg receptor activity	F	Combining with the C3dg product of the complement cascade and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
1860	complement component C3d receptor activity	F	Combining with the C3d product of the complement cascade and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
1861	complement component C4b receptor activity	F	Combining with the C4b product of the classical complement cascade and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
1862	collectin binding	F	Interacting selectively and non-covalently with a collectin, a member of a group of structurally related pattern recognition molecules characterized by having a carbohydrate recognition domain of the C-type lectin family at the C-terminus and a collagenous domain at the N-terminus.
1863	collectin receptor activity	F	Combining with a collectin and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
1864	pentraxin binding	F	Interacting selectively and non-covalently with a pentraxin, a member of a family of inflammatory proteins with a radially symmetric arrangement of five identical, noncovalently linked chains in a pentagonal array.
1865	NK T cell differentiation	P	The process in which a precursor cell type acquires the specialized features of a NK T cell.
1866	NK T cell proliferation	P	The expansion of a NK T cell population by cell division.
1867	complement activation, lectin pathway	P	Any process involved in the activation of any of the steps of the lectin pathway of the complement cascade which allows for the direct killing of microbes and the regulation of other immune processes.
1868	regulation of complement activation, lectin pathway	P	Any process that modulates the frequency, rate or extent of the lectin pathway of complement activation.
1869	negative regulation of complement activation, lectin pathway	P	Any process that stops, prevents, or reduces the rate of complement activation by the lectin pathway.
1870	positive regulation of complement activation, lectin pathway	P	Any process that activates or increases the frequency, rate or extent of complement activation by the lectin pathway.
1871	pattern binding	F	Interacting selectively and non-covalently with a repeating or polymeric structure, such as a polysaccharide or peptidoglycan.
1872	(1->3)-beta-D-glucan binding	F	Interacting selectively and non-covalently with (1->3)-beta-D-glucans.
1873	polysaccharide receptor activity	F	Combining with a polysaccharide and transmitting the signal to initiate a change in cell activity. A polysaccharide is a polymer of many (typically more than 10) monosaccharide residues linked glycosidically.
1874	(1->3)-beta-D-glucan receptor activity	F	Combining with (1->3)-beta-D-glucans to initiate a change in cell activity.
1875	lipopolysaccharide receptor activity	F	Combining with a lipopolysaccharide and transmitting the signal across the cell membrane to initiate a change in cell activity. Lipopolysaccharides (LPS) are major components of the outer membrane of Gram-negative bacteria, making them prime targets for recognition by the immune system.
1876	lipoarabinomannan binding	F	Interacting selectively and non-covalently with lipoarabinomannan.
1877	lipoarabinomannan receptor activity	F	Combining with lipoarabinomannan and transmitting the signal to initiate a change in cell activity.
1878	response to yeast	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a yeast species.
1879	detection of yeast	P	The series of events in which a stimulus from a yeast is received and converted into a molecular signal.
1880	Mullerian duct regression	P	The process in which the Mullerian ducts, primordia of the oviducts, uterus and upper vagina, undergo regression in male embryos.
1881	receptor recycling	P	The process that results in the return of receptor molecules to an active state and an active cellular location after they have been stimulated by a ligand. An active state is when the receptor is ready to receive a signal.
1882	nucleoside binding	F	Interacting selectively and non-covalently with a nucleoside, a compound consisting of a purine or pyrimidine nitrogenous base linked either to ribose or deoxyribose.
1883	purine nucleoside binding	F	Interacting selectively and non-covalently with a purine nucleoside, a compound consisting of a purine base linked either to ribose or deoxyribose.
1884	pyrimidine nucleoside binding	F	Interacting selectively and non-covalently with a pyrimidine nucleoside, a compound consisting of a pyrimidine base linked either to ribose or deoxyribose.
1885	endothelial cell development	P	The progression of an endothelial cell over time, from its formation to the mature structure.
1886	endothelial cell morphogenesis	P	The change in form (cell shape and size) that occurs during the differentiation of an endothelial cell.
1887	selenium compound metabolic process	P	The chemical reactions and pathways involving compounds that contain selenium, such as selenocysteine.
1888	glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity	F	Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + beta-D-glucuronosyl-(1->3)-beta-D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-xylosyl-proteoglycan = UDP + alpha-N-acetyl-D-glucosaminyl-(1->4)-beta-D-glucuronosyl-(1->3)-beta-D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-xylosyl-proteoglycan.
1889	liver development	P	The process whose specific outcome is the progression of the liver over time, from its formation to the mature structure. The liver is an exocrine gland which secretes bile and functions in metabolism of protein and carbohydrate and fat, synthesizes substances involved in the clotting of the blood, synthesizes vitamin A, detoxifies poisonous substances, stores glycogen, and breaks down worn-out erythrocytes.
1890	placenta development	P	The process whose specific outcome is the progression of the placenta over time, from its formation to the mature structure. The placenta is an organ of metabolic interchange between fetus and mother, partly of embryonic origin and partly of maternal origin.
1891	phagocytic cup	C	An invagination of the cell membrane formed by an actin dependent process during phagocytosis. Following internalization it is converted into a phagosome.
1892	embryonic placenta development	P	The embryonically driven process whose specific outcome is the progression of the placenta over time, from its formation to the mature structure. The placenta is an organ of metabolic interchange between fetus and mother, partly of embryonic origin and partly of maternal origin.
1893	maternal placenta development	P	Maternally driven process whose specific outcome is the progression of the placenta over time, from its formation to the mature structure. The placenta is an organ of metabolic interchange between fetus and mother, partly of embryonic origin and partly of maternal origin.
1894	tissue homeostasis	P	A homeostatic process involved in the maintenance of an internal steady state within a defined tissue of an organism, including control of cellular proliferation and death and control of metabolic function.
1895	retina homeostasis	P	A tissue homeostatic process involved in the maintenance of an internal equilibrium within the retina of the eye, including control of cellular proliferation and death and control of metabolic function.
1896	autolysis	P	A programmed cell death process observed in bacteria and filamentous fungi and leading to spontaneous death by lysis. Examples are lysis of the mother cell during sporulation of Bacillus subtilis and self-degradation of fungal cells in Aspergillus nidulans. Autolysis is also involved in bacterial biofilm formation.
1897	cytolysis by symbiont of host cells	P	The killing by an organism of a cell in its host organism by means of the rupture of cell membranes and the loss of cytoplasm. The host is defined as the larger of the organisms involved in a symbiotic interaction.
1898	regulation of cytolysis by symbiont of host cells	P	Any process in which an organism modulates the frequency, rate or extent of the cytolysis by that organism of cells in its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
1899	negative regulation of cytolysis by symbiont of host cells	P	Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of cytolysis by that organism of cells in its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
1900	positive regulation of cytolysis by symbiont of host cells	P	Any process in which an organism activates or increases the frequency, rate or extent of cytolysis by that organism of cells in its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
1905	activation of membrane attack complex	P	The activation of the membrane attack complex components of the complement cascade which can result in death of a target cell through cytolysis.
1906	cell killing	P	Any process in an organism that results in the killing of its own cells or those of another organism, including in some cases the death of the other organism. Killing here refers to the induction of death in one cell by another cell, not cell-autonomous death due to internal or other environmental conditions.
1907	killing by symbiont of host cells	P	Any process mediated by an organism that results in the death of cells in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
1909	leukocyte mediated cytotoxicity	P	The directed killing of a target cell by a leukocyte.
1910	regulation of leukocyte mediated cytotoxicity	P	Any process that modulates the frequency, rate, or extent of leukocyte mediated cytotoxicity.
1911	negative regulation of leukocyte mediated cytotoxicity	P	Any process that stops, prevents, or reduces the rate of leukocyte mediated cytotoxicity.
1912	positive regulation of leukocyte mediated cytotoxicity	P	Any process that activates or increases the frequency, rate or extent of leukocyte mediated cytotoxicity.
1913	T cell mediated cytotoxicity	P	The directed killing of a target cell by a T cell through the release of granules containing cytotoxic mediators or through the engagement of death receptors.
1914	regulation of T cell mediated cytotoxicity	P	Any process that modulates the frequency, rate, or extent of T cell mediated cytotoxicity.
1915	negative regulation of T cell mediated cytotoxicity	P	Any process that stops, prevents, or reduces the rate of T cell mediated cytotoxicity.
1916	positive regulation of T cell mediated cytotoxicity	P	Any process that activates or increases the frequency, rate or extent of T cell mediated cytotoxicity.
1917	photoreceptor inner segment	C	The inner segment of a vertebrate photoreceptor containing mitochondria, ribosomes and membranes where opsin molecules are assembled and passed to be part of the outer segment discs.
1918	farnesylated protein binding	F	Interacting selectively and non-covalently with a farnesylated protein.
1919	regulation of receptor recycling	P	Any process that modulates the frequency, rate, or extent of receptor recycling.
1920	negative regulation of receptor recycling	P	Any process that stops, prevents, or reduces the rate of receptor recycling.
1921	positive regulation of receptor recycling	P	Any process that activates or increases the frequency, rate or extent of receptor recycling.
1922	B-1 B cell homeostasis	P	The process of regulating the proliferation and elimination of B cells of the B-1 subset such that the total number of B-1 B cells within a whole or part of an organism is stable over time in the absence of an outside stimulus. B-1 B cells are a distinct subset of B cells characterized as being CD5 positive, found predominantly in the peritoneum, pleural cavities, and spleen, and enriched for self-reactivity.
1923	B-1 B cell differentiation	P	The process in which a hemopoietic stem cell acquires the specialized features of a B-1 B cell. B-1 B cells are a distinct subset of B cells characterized as being CD5 positive, found predominantly in the peritoneum, pleural cavities, and spleen, and enriched for self-reactivity.
1924	regulation of B-1 B cell differentiation	P	Any process that modulates the frequency, rate, or extent of B-1 B cell differentiation. B-1 B cells are a distinct subset of B cells characterized as being CD5 positive, found predominantly in the peritoneum, pleural cavities, and spleen, and enriched for self-reactivity.
1925	negative regulation of B-1 B cell differentiation	P	Any process that stops, prevents, or reduces the rate of B-1 B cell differentiation.
1926	positive regulation of B-1 B cell differentiation	P	Any process that activates or increases the frequency, rate or extent of B-1 B cell differentiation.
1927	exocyst assembly	P	The aggregation, arrangement and bonding together of various polypeptides into the exocyst complex.
1928	regulation of exocyst assembly	P	Any process that modulates the frequency, rate or extent of exocyst assembly.
1929	negative regulation of exocyst assembly	P	Any process that stops, prevents, or reduces the rate or extent of exocyst assembly.
1930	positive regulation of exocyst assembly	P	Any process that increases the rate or extent of exocyst assembly.
1931	uropod	C	A membrane projection with related cytoskeletal components at the trailing edge of a cell in the process of migrating or being activated, found on the opposite side of the cell from the leading edge or immunological synapse, respectively.
1932	regulation of protein phosphorylation	P	Any process that modulates the frequency, rate or extent of addition of phosphate groups into an amino acid in a protein.
1933	negative regulation of protein phosphorylation	P	Any process that stops, prevents or reduces the rate of addition of phosphate groups to amino acids within a protein.
1934	positive regulation of protein phosphorylation	P	Any process that activates or increases the frequency, rate or extent of addition of phosphate groups to amino acids within a protein.
1935	endothelial cell proliferation	P	The multiplication or reproduction of endothelial cells, resulting in the expansion of a cell population. Endothelial cells are thin flattened cells which line the inside surfaces of body cavities, blood vessels, and lymph vessels, making up the endothelium.
1936	regulation of endothelial cell proliferation	P	Any process that modulates the frequency, rate, or extent of endothelial cell proliferation.
1937	negative regulation of endothelial cell proliferation	P	Any process that stops, prevents, or reduces the rate or extent of endothelial cell proliferation.
1938	positive regulation of endothelial cell proliferation	P	Any process that activates or increases the rate or extent of endothelial cell proliferation.
1939	female pronucleus	C	The pronucleus originating from the ovum that is being fertilized.
1940	male pronucleus	C	The pronucleus originating from the spermatozoa that was involved in fertilization.
1941	postsynaptic membrane organization	P	A process which results in the assembly, arrangement of constituent parts, or disassembly of a postsynaptic membrane, the specialized area of membrane facing the presynaptic membrane on the tip of the nerve ending and separated from it by a minute cleft (the synaptic cleft).
1942	hair follicle development	P	The process whose specific outcome is the progression of the hair follicle over time, from its formation to the mature structure. A hair follicle is a tube-like opening in the epidermis where the hair shaft develops and into which the sebaceous glands open.
1944	vasculature development	P	The process whose specific outcome is the progression of the vasculature over time, from its formation to the mature structure. The vasculature is an interconnected tubular multi-tissue structure that contains fluid that is actively transported around the organism.
1945	lymph vessel development	P	The process whose specific outcome is the progression of a lymph vessel over time, from its formation to the mature structure.
1946	lymphangiogenesis	P	Lymph vessel formation when new vessels emerge from the proliferation of pre-existing vessels.
1947	heart looping	P	The tube morphogenesis process in which the primitive heart tube loops asymmetrically. This looping brings the primitive heart chambers into alignment preceding their future integration. Heart looping begins with dextral-looping and ends when the main regional divisions of the mature heart and primordium of the great arterial trunks become established preceeding septation.
1948	glycoprotein binding	F	Interacting selectively and non-covalently with a glycoprotein, a protein that contains covalently bound glycose (monosaccharide) residues. These also include proteoglycans.
1949	sebaceous gland cell differentiation	P	The process in which a relatively unspecialized epidermal cell acquires the specialized features of a sebaceous gland cell.
1951	intestinal D-glucose absorption	P	Uptake of D-glucose into the blood by absorption from the small intestine.
1952	regulation of cell-matrix adhesion	P	Any process that modulates the frequency, rate or extent of attachment of a cell to the extracellular matrix.
1953	negative regulation of cell-matrix adhesion	P	Any process that stops, prevents, or reduces the rate or extent of cell adhesion to the extracellular matrix.
1954	positive regulation of cell-matrix adhesion	P	Any process that activates or increases the rate or extent of cell adhesion to an extracellular matrix.
1955	blood vessel maturation	P	A developmental process, independent of morphogenetic (shape) change, that is required for a blood vessel to attain its fully functional state.
1956	positive regulation of neurotransmitter secretion	P	Any process that activates or increases the frequency, rate or extent of the regulated release of a neurotransmitter.
1957	intramembranous ossification	P	Direct ossification that occurs within mesenchyme or an accumulation of relatively unspecialized cells.
1958	endochondral ossification	P	Replacement ossification wherein bone tissue replaces cartilage.
1959	regulation of cytokine-mediated signaling pathway	P	Any process that modulates the frequency, rate or extent of the cytokine mediated signaling pathway.
1960	negative regulation of cytokine-mediated signaling pathway	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the cytokine mediated signaling pathway.
1961	positive regulation of cytokine-mediated signaling pathway	P	Any process that activates or increases the frequency, rate or extent of a cytokine mediated signaling pathway.
1962	alpha-1,3-galactosyltransferase activity	F	Catalysis of the transfer of a galactose residue from a donor molecule, such as GDP-galactose or UDP-galactose, to an oligosaccharide, forming an alpha-(1->3) linkage.
1963	synaptic transmission, dopaminergic	P	The process of communication from a neuron to another neuron across a synapse using the neurotransmitter dopamine.
1964	startle response	P	An action or movement due to the application of a sudden unexpected stimulus.
1965	G-protein alpha-subunit binding	F	Interacting selectively and non-covalently with a G-protein alpha subunit. The alpha subunit binds a guanine nucleotide.
1966	thigmotaxis	P	The directed movement of a motile cell or organism in response to touch.
1967	suckling behavior	P	Specific behavior of a newborn or infant mammal that results in the derivation of nourishment from the breast.
1968	fibronectin binding	F	Interacting selectively and non-covalently with a fibronectin, a group of related adhesive glycoproteins of high molecular weight found on the surface of animal cells, connective tissue matrices, and in extracellular fluids.
1969	regulation of activation of membrane attack complex	P	Any process that modulates the frequency, rate or extent of the activation of the membrane attack complex components of the complement cascade.
1970	positive regulation of activation of membrane attack complex	P	Any process that activates, maintains or increases the frequency, rate or extent of the activation of the membrane attack complex components of the complement cascade.
1971	negative regulation of activation of membrane attack complex	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the activation of the membrane attack complex components of the complement cascade.
1972	retinoic acid binding	F	Interacting selectively and non-covalently with retinoic acid, 3,7-dimethyl-9-(2,6,-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoic acid.
1973	adenosine receptor signaling pathway	P	The series of molecular signals generated as a consequence of a receptor binding to extracellular adenosine and transmitting the signal to a heterotrimeric G-protein complex to initiate a change in cell activity.
1974	blood vessel remodeling	P	The reorganization or renovation of existing blood vessels.
1975	response to amphetamine	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amphetamine stimulus. Amphetamines consist of a group of compounds related to alpha-methylphenethylamine.
1976	neurological system process involved in regulation of systemic arterial blood pressure	P	The regulation of blood pressure mediated by detection of stimuli and a neurological response.
1977	renal system process involved in regulation of blood volume	P	A slow mechanism of blood pressure regulation that responds to changes in pressure resulting from fluid and salt intake by modulating the quantity of blood in the circulatory system.
1978	regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback	P	The process that modulates blood pressure by sensing the amount of stretch occurring in large arteries and responding to the input via central nervous system control.
1979	regulation of systemic arterial blood pressure by chemoreceptor signaling	P	The process that modulates blood pressure by the action of chemoreceptors found in the carotid and aortic bodies and their resultant modulation of the vasomotor center. Chemoreceptors respond to oxygen, carbon dioxide and hydrogen ions.
1980	regulation of systemic arterial blood pressure by ischemic conditions	P	The process that modulates blood pressure by the detection of carbon dioxide levels in the brain stem. Increased levels activate the sympathetic vasoconstrictor mechanism increasing the force with which blood flows through the circulatory system.
1981	baroreceptor detection of arterial stretch	P	The series of events by which the change in diameter of an artery is detected and converted to a molecular signal.
1982	baroreceptor response to decreased systemic arterial blood pressure	P	The lowering of the number of nerve impulses from baroreceptors as a result of decreased stretch of an artery that results in an increased in sympathetic nerve impulses to peripheral blood vessels.
1983	baroreceptor response to increased systemic arterial blood pressure	P	The increase in nerve impulses from baroreceptors as a result of increased pressure on an artery that results in an inhibition of sympathetic nerve impulses to peripheral blood vessels.
1984	vasodilation of artery involved in baroreceptor response to increased systemic arterial blood pressure	P	An increase in the internal diameter of an artery, triggered by vasomotor suppression, during the chemoreceptor response to decreased blood pressure.
1985	negative regulation of heart rate involved in baroreceptor response to increased systemic arterial blood pressure	P	Any process that stops, prevents, or reduces the frequency, rate or extent of heart contraction as a result of the baroreceptor response to increased blood pressure.
1986	negative regulation of the force of heart contraction involved in baroreceptor response to increased systemic arterial blood pressure	P	Any process that decreases the force with which the cardiac muscles of the heart pump blood through the circulatory system as a result of the baroreceptor response to increased blood pressure.
1987	vasoconstriction of artery involved in baroreceptor response to lowering of systemic arterial blood pressure	P	A process that is triggered by vasomotor excitation and results in a decrease in the diameter of an artery during the baroreceptor response to decreased blood pressure.
1988	positive regulation of heart rate involved in baroreceptor response to decreased systemic arterial blood pressure	P	Any process that activates, maintains or increases the frequency, rate or extent of heart contraction as a result of the baroreceptor response to decreased blood pressure.
1989	positive regulation of the force of heart contraction involved in baroreceptor response to decreased systemic arterial blood pressure	P	Any process that increases the force with which the cardiac muscles of the heart pump blood through the circulatory system as part of the baroreceptor response to decreased blood pressure.
1990	regulation of systemic arterial blood pressure by hormone	P	The process in which hormones modulate the force with which blood passes through the circulatory system. A hormone is one of a group of substances formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells, in the same organism, upon which they have a specific regulatory action.
1991	regulation of systemic arterial blood pressure by circulatory renin-angiotensin	P	The process in which angiotensinogen metabolites in the bloodstream modulate the force with which blood passes through the circulatory system. The process begins when renin is released and cleaves angiotensinogen.
1992	regulation of systemic arterial blood pressure by vasopressin	P	The regulation of blood pressure mediated by the signaling molecule vasopressin. Vasopressin is produced in the hypothalamus, and affects vasoconstriction, and renal water transport.
1993	regulation of systemic arterial blood pressure by norepinephrine-epinephrine	P	The process in which the secretion of norepinephrine or epinephrine into the bloodstream modulates the force with which blood passes through the circulatory system.
1994	norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure	P	A process that results in a decrease in the diameter of an artery during the norepinephrine-epinephrine response to decreased blood pressure.
1995	norepinephrine-epinephrine catabolic process in blood stream	P	The chemical reactions and pathways resulting in the breakdown of norepinephrine or epinephrine in the bloodstream.
1996	positive regulation of heart rate by epinephrine-norepinephrine	P	The process in which the presence of epinephrine or norepinephrine in the bloodstream activates, maintains or increases the rate of heart contraction.
1997	positive regulation of the force of heart contraction by epinephrine-norepinephrine	P	Any process that increases the force with which the cardiac muscles of the heart pump blood through the circulatory system as a result of the presence of epinephrine or norepinephrine in the bloodstream or released from the nerve endings.
1998	angiotensin-mediated vasoconstriction involved in regulation of systemic arterial blood pressure	P	The decrease in blood vessel diameter as a result of the release of angiotensin into the blood stream.
1999	renal response to blood flow involved in circulatory renin-angiotensin regulation of systemic arterial blood pressure	P	The physiological response of the kidneys to a decrease in blood flow.
2000	detection of renal blood flow	P	The process in which the juxtaglomerular cells of the kidneys receive information about the amount of blood flowing through the arterioles and converts the information to a molecular signal.
2001	renin secretion into blood stream	P	The regulated release of renin into the blood stream by juxtoglomerular cells.
2002	regulation of angiotensin levels in blood	P	The process that modulates the level of angiotensin in the blood by balancing the maturation of renin substrate to mature angiotensin and the catabolism of mature angiotensin.
2003	angiotensin maturation	P	The process leading to the attainment of the full functional capacity of angiotensin by conversion of renin substrate into mature angiotensin in the blood.
2004	secretion of vasopressin involved in fast regulation of systemic arterial blood pressure	P	The regulated release of the hormone vasopressin into the blood stream by the hypothalamus and pituitary gland contributing to fast regulation of blood pressure.
2005	angiotensin catabolic process in blood	P	The chemical reactions and pathways resulting in the breakdown of angiotensin in the blood.
2006	vasoconstriction by vasopressin involved in systemic arterial blood pressure control	P	The decrease in blood vessel diameter as a result of the release of vasopressin into the blood stream.
2007	detection of hypoxic conditions in blood by chemoreceptor signaling	P	The process in which information about a lack of oxygen are received and are converted to a molecular signal by chemoreceptors in the carotid bodies and the aortic bodies.
2008	excitation of vasomotor center by chemoreceptor signaling	P	The process in which the molecular signal from the carotid and aortic bodies is relayed to the vasomotor center, causing it to signal an increase arterial pressure.
2009	morphogenesis of an epithelium	P	The process in which the anatomical structures of epithelia are generated and organized. An epithelium consists of closely packed cells arranged in one or more layers, that covers the outer surfaces of the body or lines any internal cavity or tube.
2010	excitation of vasomotor center by baroreceptor signaling	P	The process in which the molecular signal from the arterial baroreceptors is relayed to the vasomotor center causing it to signal increase arterial pressure.
2011	morphogenesis of an epithelial sheet	P	The process in which the anatomical structures of an epithelial sheet are generated and organized. An epithelial sheet is a flat surface consisting of closely packed epithelial cells.
2012	vasoconstriction of artery involved in chemoreceptor response to lowering of systemic arterial blood pressure	P	A process that is triggered by vasomotor excitation and results in a decrease in the diameter of an artery during the chemoreceptor response to decreased blood pressure.
2013	detection of carbon dioxide by vasomotor center	P	The process by a carbon dioxide stimulus is received and converted to a molecular signal by the vasomotor center of the central nervous system.
2014	vasoconstriction of artery involved in ischemic response to lowering of systemic arterial blood pressure	P	The vasoconstriction that is triggered by vasomotor excitation resulting from the detection of high carbon dioxide levels in the vasomotor center of the central nervous system.
2015	regulation of systemic arterial blood pressure by atrial baroreceptor feedback	P	A process that controls blood pressure by sensing the amount of stretch occurring in the atria.
2016	regulation of blood volume by renin-angiotensin	P	The process in which the renin-angiotensin system controls the rate of fluid intake and output into the blood.
2017	regulation of blood volume by renal aldosterone	P	The process in which the hormone aldosterone decreases the rate of diuresis and natriuresis resulting in increased blood volume.
2018	renin-angiotensin regulation of aldosterone production	P	The process in which an increase in active angiotensin stimulates the adrenal cortices to secrete aldosterone.
2019	regulation of renal output by angiotensin	P	The process in which angiotensin directly modulates the rate of urine output by the kidney.
2020	protease binding	F	Interacting selectively and non-covalently with any protease or peptidase.
2021	response to dietary excess	P	The physiological process in which dietary excess is sensed by the central nervous system, resulting in a reduction in food intake and increased energy expenditure.
2022	detection of dietary excess	P	The neurological process in which the brain senses excessive caloric intake.
2023	reduction of food intake in response to dietary excess	P	An eating behavior process whereby detection of a dietary excess results in a decrease in intake of nutrients.
2024	diet induced thermogenesis	P	The process that results in increased metabolic rate in tissues of an organism. It is triggered by the detection of dietary excess. This process is achieved via signalling in the sympathetic nervous system.
2025	vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure	P	A process that results in an increase in the diameter of an artery during the norepinephrine-epinephrine response to blood pressure change.
2026	regulation of the force of heart contraction	P	Any process that modulates the extent of heart contraction, changing the force with which blood is propelled.
2027	regulation of heart rate	P	Any process that modulates the frequency or rate of heart contraction.
2028	regulation of sodium ion transport	P	Any process that modulates the frequency, rate or extent of the directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
2029	desensitization of G-protein coupled receptor protein signaling pathway	P	The process that stops, prevents, or reduces the frequency, rate or extent of G-protein coupled receptor protein signaling pathway activity after prolonged stimulation with an agonist of the pathway.
2030	inhibitory G-protein coupled receptor phosphorylation	P	The process that inhibits the signaling function of a G-protein coupled receptor by addition of a phosphate group to its third intracellular loop consensus site.
2031	G-protein coupled receptor internalization	P	The process that results in the uptake of a G-protein coupled receptor into an endocytic vesicle.
2032	desensitization of G-protein coupled receptor protein signaling pathway by arrestin	P	The process that inhibits the signaling function of a G-protein coupled receptor by uncoupling the receptor from its downstream G proteins.
2033	angiotensin-mediated vasodilation involved in regulation of systemic arterial blood pressure	P	The process that increases the diameter of a blood vessel via the renin-angiotensin system.
2034	regulation of blood vessel diameter by renin-angiotensin	P	The process in which the diameter of a blood vessel is changed due to activity of the renin-angiotensin system.
2035	brain renin-angiotensin system	P	The process in which an angiotensin-mediated signaling system present in the brain regulates the force with which blood passes through the circulatory system.
2036	regulation of L-glutamate transport	P	Any process that modulates the frequency, rate or extent of L-glutamate transport.
2037	negative regulation of L-glutamate transport	P	Any process that stops, prevents, or reduces the frequency, rate or extent of L-glutamate transport.
2038	positive regulation of L-glutamate transport	P	Any process that activates or increases the frequency, rate or extent of L-glutamate transport.
2039	p53 binding	F	Interacting selectively and non-covalently with one of the p53 family of proteins.
2040	sprouting angiogenesis	P	The extension of new blood vessels from existing capillaries into avascular tissues resulting from the proliferation of blood vessel endothelial cells.
2041	intussusceptive angiogenesis	P	The formation of new blood vessels as a result of the insertion and extension of lumenal tissue pillars.
2042	cell migration involved in sprouting angiogenesis	P	The orderly movement of endothelial cells into the extracellular matrix in order to form new blood vessels involved in sprouting angiogenesis.
2043	blood vessel endothelial cell proliferation involved in sprouting angiogenesis	P	The multiplication or reproduction of blood vessel endothelial cells, resulting in the expansion of a cell population contributing to sprouting angiogenesis.
2044	blood vessel endothelial cell migration involved in intussusceptive angiogenesis	P	The orderly movement of endothelial cells into the extracellular matrix in order to form new blood vessels during intussusceptive angiogenesis.
2045	regulation of cell adhesion involved in intussusceptive angiogenesis	P	The process that modulates the frequency, rate or extent of attachment of a blood vessel endothelial cell to another cell or to the extracellular matrix involved in intussusceptive angiogenesis.
2046	opsin binding	F	Interacting selectively and non-covalently with an opsin, any of a group of hydrophobic, integral membrane glycoproteins located primarily in the disc membrane of rods or cones, involved in photoreception.
2047	phenazine biosynthetic process	P	The chemical reactions and pathways resulting in the formation of a phenazine antibiotic, a polycyclic pyrazine with two nitrogen atoms in the ring.
2048	pyoverdine metabolic process	P	The chemical reactions and pathways involving the siderochrome pyoverdine.
2049	pyoverdine biosynthetic process	P	The chemical reactions and pathways resulting in the formation of the siderochrome pyoverdine.
2050	pyoverdine catabolic process	P	The chemical reactions and pathways resulting in the breakdown of the siderochrome pyoverdine.
2051	osteoblast fate commitment	P	The commitment of mesenchymal cells to the specific cell fate of an osteoblast. An osteoblast is a bone-forming cell which secretes an extracellular matrix. Hydroxyapatite crystals are then deposited into the matrix to form bone.
2052	positive regulation of neuroblast proliferation	P	Any process that activates or increases the rate of neuroblast proliferation.
2053	positive regulation of mesenchymal cell proliferation	P	The process of activating or increasing the rate or extent of mesenchymal cell proliferation. Mesenchymal cells are loosely organized embryonic cells.
2054	nucleobase binding	F	Interacting selectively and non-covalently with a nucleobase, any of a class of pyrmidines or purines, organic nitrogenous bases.
2055	adenine binding	F	Interacting selectively and non-covalently with adenine, a purine base.
2056	cytosine binding	F	Interacting selectively and non-covalently with cytosine.
2057	guanine binding	F	Interacting selectively and non-covalently with guanine.
2058	uracil binding	F	Interacting selectively and non-covalently with uracil.
2059	thymine binding	F	Interacting selectively and non-covalently with thymine.
2060	purine nucleobase binding	F	Interacting selectively and non-covalently with a purine nucleobase, an organic nitrogenous base with a purine skeleton.
2061	pyrimidine nucleobase binding	F	Interacting selectively and non-covalently with a pyrimidine nucleobase, an organic nitrogenous base with a pyrimidine skeleton.
2062	chondrocyte differentiation	P	The process in which a chondroblast acquires specialized structural and/or functional features of a chondrocyte. A chondrocyte is a polymorphic cell that forms cartilage.
2063	chondrocyte development	P	The process whose specific outcome is the progression of a chondrocyte over time, from its commitment to its mature state. Chondrocyte development does not include the steps involved in committing a chondroblast to a chondrocyte fate.
2064	epithelial cell development	P	The process whose specific outcome is the progression of an epithelial cell over time, from its formation to the mature structure. An epithelial cell is a cell usually found in a two-dimensional sheet with a free surface.
2065	columnar/cuboidal epithelial cell differentiation	P	The process in which a relatively unspecialized cell acquires specialized features of a columnar/cuboidal epithelial cell. A columnar/cuboidal epithelial cell is a cell usually found in a two dimensional sheet with a free surface. Columnar/cuboidal epithelial cells take on the shape of a column or cube.
2066	columnar/cuboidal epithelial cell development	P	The process whose specific outcome is the progression of a columnar/cuboidal epithelial cell over time, from its formation to the mature structure. A columnar/cuboidal epithelial cell is a cell usually found in a two dimensional sheet with a free surface. Columnar/cuboidal epithelial cells take on the shape of a column or cube.
2067	glandular epithelial cell differentiation	P	The process in which a relatively unspecialized cell acquires specialized features of a glandular epithelial cell. A glandular epithelial cell is a columnar/cuboidal epithelial cell found in a two dimensional sheet with a free surface exposed to the lumen of a gland.
2068	glandular epithelial cell development	P	The process whose specific outcome is the progression of a glandular epithelial cell over time, from its formation to the mature structure. A glandular epithelial cell is a columnar/cuboidal epithelial cell is a cell found in a two dimensional sheet with a free surface exposed to the lumen of a gland.
2069	columnar/cuboidal epithelial cell maturation	P	The developmental process, independent of morphogenetic (shape) change, that is required for a columna/cuboidal epithelial cell to attain its fully functional state. A columnar/cuboidal epithelial cell is a cell usually found in a two dimensional sheet with a free surface. Columnar/cuboidal epithelial cells take on the shape of a column or cube.
2070	epithelial cell maturation	P	The developmental process, independent of morphogenetic (shape) change, that is required for an epithelial cell to attain its fully functional state. An epithelial cell is a cell usually found in a two-dimensional sheet with a free surface.
2071	glandular epithelial cell maturation	P	The developmental process, independent of morphogenetic (shape) change, that is required for a glandular epithelial cell to attain its fully functional state. A glandular epithelial cell is a columnar/cuboidal epithelial cell is a cell found in a two dimensional sheet with a free surface exposed to the lumen of a gland.
2072	optic cup morphogenesis involved in camera-type eye development	P	The invagination of the optic vesicle to form two-walled indentations, the optic cups, that will go on to form the retina. This process begins with the optic vesicle becoming a two-walled structure and its subsequent shape changes. It does not include the fate commitment of cells to become the pigmented retina and the neural retina. An example of this process is found in Mus musculus.
2074	extraocular skeletal muscle development	P	The process whose specific outcome is the progression of the extraocular skeletal muscle over time, from its formation to the mature structure. The extraocular muscle is derived from cranial mesoderm and controls eye movements. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle. An example of this process is found in Mus musculus.
2075	somitomeric trunk muscle development	P	The process whose specific outcome is the progression of the somitomeric trunk muscle over time, from its formation to the mature structure. The somitomeric trunk muscle is derived from somitomeric mesoderm. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle. An example of this process is found in Mus musculus.
2076	osteoblast development	P	The process whose specific outcome is the progression of an osteoblast over time, from its formation to the mature structure. Osteoblast development does not include the steps involved in committing a cranial neural crest cell or an osteoprogenitor cell to an osteoblast fate. An osteoblast is a cell that gives rise to bone.
2077	acrosome matrix dispersal	P	The proteolytic digestion of components in the acrosomal matrix that allows for their release into the egg. The dispersal of the components allows for the inner acrosomal membrane to interact with the egg.
2078	membrane fusion involved in acrosome reaction	P	The fusion of the plasma membrane of the sperm with the outer acrosomal membrane.
2079	inner acrosomal membrane	C	The acrosomal membrane region that underlies the acrosomal vesicle and is located toward the sperm nucleus. This region is responsible for molecular interactions allowing the sperm to penetrate the zona pellucida and fuses with the egg plasma membrane.
2080	acrosomal membrane	C	The membrane that surrounds the acrosomal lumen. The acrosome is a special type of lysosome in the head of a spermatozoon that contains acid hydrolases and is concerned with the breakdown of the outer membrane of the ovum during fertilization.
2081	outer acrosomal membrane	C	The acrosomal membrane region that underlies the plasma membrane of the sperm. This membrane fuses with the sperm plasma membrane as part of the acrosome reaction.
2082	regulation of oxidative phosphorylation	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the phosphorylation of ADP to ATP that accompanies the oxidation of a metabolite through the operation of the respiratory chain. Oxidation of compounds establishes a proton gradient across the membrane, providing the energy for ATP synthesis.
2083	4-hydroxybenzoate decaprenyltransferase activity	F	Catalysis of the reaction: all-trans-decaprenyl diphosphate + 4-hydroxybenzoate = 3-decaprenyl-4-hydroxybenzoate + diphosphate.
2084	protein depalmitoylation	P	The removal of palymitoyl groups from a lipoprotein.
2085	inhibition of neuroepithelial cell differentiation	P	Any process that prevents the activation of neuroepithelial cell differentiation. Neuroepithelial cell differentiation is the process in which epiblast cells acquire specialized features of neuroepithelial cells.
2086	diaphragm contraction	P	A process in which force is generated within involuntary skeletal muscle tissue, resulting in a change in muscle geometry. This process occurs in the diaphragm. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The diaphragm is a striated muscle that is necessary for the process of respiratory gaseous exchange.
2087	regulation of respiratory gaseous exchange by neurological system process	P	A process carried out by the nervous system that is required for the proper control of respiratory gaseous exchange. This process occurs in the respiratory center of the brain in vertebrates.
2088	lens development in camera-type eye	P	The process whose specific outcome is the progression of the lens over time, from its formation to the mature structure. The lens is a transparent structure in the eye through which light is focused onto the retina. An example of this process is found in Mus musculus.
2089	lens morphogenesis in camera-type eye	P	The process in which the anatomical structures of the lens are generated and organized. The lens is a transparent structure in the eye through which light is focused onto the retina. An example of this process is found in Mus musculus.
2090	regulation of receptor internalization	P	Any process that modulates the frequency, rate or extent of receptor internalization.
2091	negative regulation of receptor internalization	P	Any process that stops, prevents, or reduces the frequency, rate or extent of receptor internalization.
2092	positive regulation of receptor internalization	P	Any process that activates or increases the frequency, rate or extent of receptor internalization.
2093	auditory receptor cell morphogenesis	P	Any process that alters the size or shape of an auditory receptor cell.
2094	polyprenyltransferase activity	F	Catalysis of the transfer of multiple prenyl groups from one compound (donor) to another (acceptor).
2095	caveolar macromolecular signaling complex	C	A complex composed of proteins required for beta adrenergic receptor activation of protein kinase A. It includes the Cav 12. subunit of L-type calcium channel, protein kinase A regulatory subunit 2(PKAR2), adenyl cyclase, beta-adrenergic receptor, G-alpha-S, protein phosphatase 2A (PP2A) and caveolin 3 (CAV3).
2096	polkadots	C	A punctate, filamentous structure composed of Bcl10 that appears in the cytoplasm of T-cells shortly after T-cell receptor stimulation. Polkadots stands for Punctate Oligomeric Killing and Activating DOmains Transducing Signals.
2097	tRNA wobble base modification	P	The process in which the nucleotide at position 34 in the anticodon of a tRNA is post-transcriptionally modified.
2098	tRNA wobble uridine modification	P	The process in which a uridine in position 34 of a tRNA is post-transcriptionally modified.
2099	tRNA wobble guanine modification	P	The process in which a guanine in t position 34 of a tRNA is post-transcriptionally modified.
2100	tRNA wobble adenosine to inosine editing	P	The process in which an adenosine in position 34 of a tRNA is post-transcriptionally converted to inosine.
2101	tRNA wobble cytosine modification	P	The process in which a cytosine in position 34 of a tRNA is post-transcriptionally modified.
2102	podosome	C	An actin-rich adhesion structure characterized by formation upon cell substrate contact and localization at the substrate-attached part of the cell, contain an F-actin-rich core surrounded by a ring structure containing proteins such as vinculin and talin, and have a diameter of 0.5 mm.
2103	endonucleolytic cleavage of tetracistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 4.5S-rRNA, 5S-rRNA)	P	Endonucleolytic cleavage of a pre-rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, Large Subunit (LSU) the 4.5S rRNA, and the 5S rRNA in that order from 5' to 3' along the primary transcript. Primary ribosomal RNA transcripts with four genes, in this order, are produced in the chloroplasts of vascular plants. Note that the use of the word tetracistronic refers only to the number of mature rRNA molecules which will be produced from the primary transcript and ignores tRNAs that may also be present within the primary transcript.
2104	endonucleolytic cleaveage between 4.5S rRNA and 5S rRNA of tetracistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 4.5S-rRNA, 5S-rRNA)	P	Endonucleolytic cleavage between the 5S rRNA and the 4.5S rRNA of an rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, Large Subunit (LSU) the 4.5S rRNA, and the 5S rRNA in that order from 5' to 3' along the primary transcript. Note that the use of the word tetracistronic refers only to the number of mature rRNA molecules which will be produced from the primary transcript and ignores tRNAs that may also be present within the primary transcript.
2105	endonucleolytic cleaveage between LSU-rRNA and 4.5S rRNA of tetracistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 4.5S-rRNA, 5S-rRNA)	P	Endonucleolytic cleavage between the LSU-rRNA and the 4.5S rRNA of an rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, Large Subunit (LSU) the 4.5S rRNA, and the 5S rRNA in that order from 5' to 3' along the primary transcript. Note that the use of the word tetracistronic refers only to the number of mature rRNA molecules which will be produced from the primary transcript and ignores tRNAs that may also be present within the primary transcript.
2106	endonucleolytic cleaveage between SSU-rRNA and LSU-rRNA of tetracistronic rRNA transcript (SSU-rRNA, LSU-rRNA, 4.5S-rRNA, 5S-rRNA)	P	Endonucleolytic cleavages between the SSU-rRNA and the LSU-rRNA of an rRNA molecule originally produced as a tetracistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, Large Subunit (LSU) the 4.5S rRNA, and the 5S rRNA in that order from 5' to 3' along the primary transcript. These cleavages liberate tRNAs from the polycistronic transcript as well as separating the SSU and LSU containing transcript. Note that the use of the word tetracistronic refers only to the number of mature rRNA molecules which will be produced from the primary transcript and ignores tRNAs that may also be present within the primary transcript.
2107	generation of mature 3'-end of 5S rRNA generated by RNA polymerase III	P	The removal of extra uridine residues from the 3' end of a 5S pre-rRNA generated by transcription by RNA polymerase III to generate the mature 3'-end.
2108	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, LSU-rRNA,5S)	P	Any process involved in the maturation of a precursor Large SubUnit (LSU) ribosomal RNA (rRNA) molecule into a mature LSU-rRNA molecule from the pre-rRNA molecule originally produced as a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, Large Subunit (LSU) the 5S rRNA in that order from 5' to 3' along the primary transcript.
2109	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, LSU-rRNA,5S)	P	Any process involved in the maturation of a precursor Small SubUnit (SSU) ribosomal RNA (rRNA) molecule into a mature SSU-rRNA molecule from the pre-rRNA molecule originally produced as a tricistronic rRNA transcript that contains the Small Subunit (SSU) rRNA, Large Subunit (LSU) the 5S rRNA in that order from 5' to 3' along the primary transcript.
2110	cotranscriptional mitochondrial rRNA nucleotide insertion	P	The insertion of one or two non-coded nucleotides during the transcription of a mitochondrial rRNA. Such additions are known to occur in myxomycetes such as Physarum, Didymium, and Stemonitis.
2111	BRCA2-BRAF35 complex	C	A heterodimeric complex of BRCA2 and BRAF35 (BRCA2-associated factor 35). The BRCA2-BRAF35 complex is often associated with condensed chromatin during mitosis.
2112	interleukin-33 receptor binding	F	Interacting selectively and non-covalently with the interleukin-33 receptor.
2113	interleukin-33 binding	F	Interacting selectively and non-covalently with interleukin-33.
2114	interleukin-33 receptor activity	F	Combining with interleukin-33 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
2115	store-operated calcium entry	P	A calcium ion entry mechanism in the plasma membrane activated by the depletion of calcium ion from the internal calcium ion store in the endoplasmic reticulum.
2116	semaphorin receptor complex	C	A stable binary complex of a neurophilin and a plexin, together forming a functional semaphorin receptor.
2117	amphibian larval development	P	The process whose specific outcome is the progression of the amphibian larva over time, from its formation to the mature structure. Amphibian larvae, sometimes called pollywogs or tadpoles, hatch from eggs and begin to grow limbs and other adult physical features at various times, depending on the species, before they metamorphose into the adult form.
2118	aggressive behavior	P	A behavioral interaction between organisms in which one organism has the intention of inflicting physical damage on another individual.
2119	nematode larval development	P	The process whose specific outcome is the progression of the nematode larva over time, from its formation to the mature structure. Nematode larval development begins with the newly hatched first-stage larva (L1) and ends with the end of the last larval stage (for example the fourth larval stage (L4) in C. elegans). Each stage of nematode larval development is characterized by proliferation of specific cell lineages and an increase in body size without alteration of the basic body plan. Nematode larval stages are separated by molts in which each stage-specific exoskeleton, or cuticle, is shed and replaced anew.
2120	predatory behavior	P	Aggressive behavior involving attack on prey by a predator.
2121	inter-male aggressive behavior	P	Aggressive behavior based on competition between males of the same species over access to resources such as females, dominance, status, etc. and characterized by noise, threats, and is often less injurious.
2122	fear-induced aggressive behavior	P	Aggressive behavior associated with attempts to flee from a threat.
2123	irritable aggressive behavior	P	Aggressive behavior induced by frustration and directed against an available target.
2124	territorial aggressive behavior	P	Aggressive behavior performed in defence of a fixed area against intruders, typically conspecifics.
2125	maternal aggressive behavior	P	Aggressive behavior of a female to protect her offspring from a threat.
2126	instrumental aggressive behavior	P	Aggressive behavior directed towards obtaining some goal, considered to be a learned response to a situation.
2127	wobble base cytosine methylation	P	The process in which the base of cytosine at position 34 in the anticodon of a tRNA is post-transcriptionally methylated at the C5 position.
2128	tRNA nucleoside ribose methylation	P	The process that results in the modification of the sugar of a nucleoside in tRNA at the 2'O position.
2129	wobble position guanine ribose methylation	P	The process in which the ribose of guanosine at position 34 in the anticodon of a tRNA is post-transcriptionally methylated at the 2'-O position.
2130	wobble position ribose methylation	P	The process in which the ribose base of the nucleotide at position 34 in the anticodon of a tRNA is post-transcriptionally methylated at the 2'O position.
2131	wobble position cytosine ribose methylation	P	The process in which the ribose of cytidine at position 34 in the anticodon of a tRNA is post-transcriptionally methylated at the 2'-O position.
2132	wobble position uridine ribose methylation	P	The process in which the ribose of uridine at position 34 in the anticodon of a tRNA is post-transcriptionally methylated at the 2'-O position.
2133	polycystin complex	C	A stable heterodimeric complex composed of polycystin-1 and polycystin-2.
2134	UTP binding	F	Interacting selectively and non-covalently with UTP, uridine 5'-triphosphate.
2135	CTP binding	F	Interacting selectively and non-covalently with CTP, cytidine 5'-triphosphate.
2136	wobble base lysidine biosynthesis	P	The process in which the carbonyl of cytosine at position 34 of a tRNA is post-transcriptionally replaced by lysine.
2138	retinoic acid biosynthetic process	P	The chemical reactions and pathways resulting in the biosynthesis of retinoic acid, one of the three components that makes up vitamin A.
2139	stereocilia coupling link	C	A structure involved in coupling stereocilia to one another in sensory hair cells There are four morphologically distinct types: tip links, horizontal top connectors, shaft connectors and ankle links. Tip links and horizontal top connectors are the only inter-stereocilia links associated with mature cochlea, whereas ankle links appear during development of the auditory hair bundle.
2140	stereocilia tip link	C	A stereocilia link that is formed by a fine filament running more or less vertically upward from the tip of each shorter stereocilium to attach at a higher point on its adjacent taller neighbor. Tilting the bundle puts tension on the filaments, which pull on mechanically gated ion channels in the membrane of the stereocilia.
2141	stereocilia ankle link	C	A stereocilia coupling link that is composed of a fine filament present in developing stereocilia that couples the bases of individual stereocilia to one another. They are not present in mature stereocilia.
2142	stereocilia ankle link complex	C	A complex of proteins that connect growing stereocilia in developing cochlear hair cells, composed of Vlgr1, usherin, vezatin, and whirlin.
2143	tRNA wobble position uridine thiolation	P	The process in which a uridine residue at position 34 in the anticodon of a tRNA is post-transcriptionally thiolated at the C2 position. This process involves transfer of a sulfur from cysteine to position C2 by several steps.
2144	cytosolic tRNA wobble base thiouridylase complex	C	A complex of two proteins involved in the thiolation of U34 in glutamate, lysine, and glutamine tRNAs of eukaryotes.
2145	4-amino-5-hydroxymethyl-2-methylpyrimidine diphosphatase activity	F	Catalysis of the reaction: 4-amino-5-hydroxymethyl-2-methylpyrimidine pyrophosphate + H2O = hydroxymethylpyrimidine phosphate + phosphate + H(+).
2146	steroid hormone receptor import into nucleus	P	The directed movement of a steroid hormone receptor into the nucleus.
2147	glucocorticoid receptor import into nucleus	P	The directed movement of a glucocorticoid receptor into the nucleus.
2148	hypochlorous acid metabolic process	P	The chemical reactions and pathways involving hypochlorous acid.
2149	hypochlorous acid biosynthetic process	P	The chemical reactions and pathways resulting in the formation of hypochlorous acid.
2150	hypochlorous acid catabolic process	P	The chemical reactions and pathways resulting in the breakdown of hypochlorous acid.
2151	G-quadruplex RNA binding	F	Interacting selectively and non-covalently with G-quadruplex RNA structures, in which groups of four guanines adopt a flat, cyclic hydrogen-bonding arrangement known as a guanine tetrad.
2152	bile acid conjugation	P	The process in which bile acids are covalently linked to taurine or glycine.
2153	steroid receptor RNA activator RNA binding	F	Interacting selectively and non-covalently with the steroid receptor RNA activator RNA (SRA). SRA enhances steroid hormone receptor transcriptional activity as an RNA transcript by an indirect mechanism that does not involve SRA-steroid receptor binding.
2154	thyroid hormone mediated signaling pathway	P	A series of molecular signals mediated by the detection of a thyroid hormone.
2155	regulation of thyroid hormone mediated signaling pathway	P	Any process that modulates the frequency, rate or extent of a thyroid hormone mediated signaling pathway.
2156	negative regulation of thyroid hormone mediated signaling pathway	P	Any process that stops, prevents, or reduces the frequency, rate or extent of thyroid hormone mediated signaling pathway.
2157	positive regulation of thyroid hormone mediated signaling pathway	P	Any process that increases the frequency, rate or extent of thyroid hormone mediated signaling pathway.
2158	osteoclast proliferation	P	The multiplication or reproduction of osteoclasts, resulting in the expansion of an osteoclast cell population. An osteoclast is a specialized phagocytic cell associated with the absorption and removal of the mineralized matrix of bone tissue, which typically differentiates from monocytes.
2159	desmosome assembly	P	A cellular process that results in the aggregation, arrangement and bonding together of a set of components to form a desmosome. A desmosome is a patch-like intercellular junction found in vertebrate tissues, consisting of parallel zones of two cell membranes, separated by an space of 25-35 nm, and having dense fibrillar plaques in the subjacent cytoplasm.
2160	desmosome maintenance	P	The maintenance of a desmosome. A desmosome is a patch-like intercellular junctions found in vertebrate tissues, consisting of parallel zones of two cell membranes, separated by an interspace of 25-35 nm, and having dense fibrillar plaques in the subjacent cytoplasm.
2161	aminoacyl-tRNA editing activity	F	The hydrolysis of an incorrectly aminoacylated tRNA.
2162	dystroglycan binding	F	Interacting selectively and non-covalently with dystroglycan. Dystroglycan is glycoprotein found in non-muscle tissues as well as in muscle tissues, often in association with dystrophin. The native dystroglycan cleaved into two non-covalently associated subunits, alpha (N-terminal) and beta (C-terminal).
2164	larval development	P	The process whose specific outcome is the progression of the larva over time, from its formation to the mature structure. The larva is the early, immature form of an that at birth or hatching is fundamentally unlike its parent and must metamorphose before assuming the adult characters.
2165	instar larval or pupal development	P	The process whose specific outcome is the progression of the instar larva or pupa over time, from its formation to the mature structure. An example of this process is found in Drosophila melanogaster.
2167	VRK3/VHR/ERK complex	C	A ternary complex consisting of VRK3, VHR (Dusp3), and ERK1 (Mapk3) existing in neuronal cells, and is involved in regulation of the ERK signaling pathway.
2168	instar larval development	P	The process whose specific outcome is the progression of the larva over time, from its formation to the mature structure. This begins with the newly hatched first-instar larva, through its maturation to the end of the last larval stage. An example of this process is found in Drosophila melanogaster.
2169	3-methylcrotonyl-CoA carboxylase complex, mitochondrial	C	A mitochondrial protein complex which is capable of 3-methylcrotonyl-CoA carboxylase activity. In mammals, at least, consists as a dodecamer of 6 alpha and 6 beta subunits. MCCC-alpha has a covalently bound biotin essential for the ATP-dependent carboxylation. MCCC-beta possesses carboxyltransferase activity which presumably is essential for binding to 3-methylcrotonyl-CoA.
2170	high-affinity IgA receptor activity	F	Combining with high affinity with an immunoglobulin of an IgA isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
2171	low-affinity IgA receptor activity	F	Combining with low affinity with an immunoglobulin of an IgA isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
2172	high-affinity IgM receptor activity	F	Combining with high affinity with an immunoglobulin of an IgM isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
2173	low-affinity IgM receptor activity	F	Combining with low affinity with an immunoglobulin of an IgM isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
2174	mammary stem cell proliferation	P	The expansion of a mammary stem cell population by cell division. Mammary stem cells are a source of cells for growth of the mammary gland during puberty and gestation. These cells can give rise to both the luminal and myoepithelial cell types of the gland, and can regenerate the entire organ.
2175	protein localization to paranode region of axon	P	A cellular protein localization process in which a protein is transported to, or maintained at, the paranode region of an axon.
2176	male germ cell proliferation	P	The multiplication or reproduction of male germ cells, resulting in the expansion of a cell population.
2177	manchette	C	A tubular array of microtubules that extends from the perinuclear ring surrounding the spermatid nucleus to the flagellar axoneme. The manchette may also contain F-actin filaments.
2178	palmitoyltransferase complex	C	A protein complex with palmitoyltransferase activity.
2179	homodimeric serine palmitoyltransferase complex	C	A homodimeric complex which transfers a palmitoyl group onto serine, forming 3-dehydro-D-sphinganine.
2180	5-lipoxygenase complex	C	An nuclear membrane protein complex having arachidonate 5-lipoxygenase activity.
2181	cytoplasmic translation	P	The chemical reactions and pathways resulting in the formation of a protein in the cytoplasm. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein.
2182	cytoplasmic translational elongation	P	The successive addition of amino acid residues to a nascent polypeptide chain during protein biosynthesis in the cytoplasm.
2183	cytoplasmic translational initiation	P	The process preceding formation of the peptide bond between the first two amino acids of a protein in the cytoplasm. This includes the formation of a complex of the ribosome, mRNA, and an initiation complex that contains the first aminoacyl-tRNA.
2184	cytoplasmic translational termination	P	The process resulting in the release of a polypeptide chain from the ribosome in the cytoplasm, usually in response to a termination codon.
2185	creatine kinase complex	C	A protein complex having creatine kinase activity.
2186	cytosolic creatine kinase complex	C	A dimeric protein complex having creatine kinase activity.
2187	mitochondrial creatine kinase complex	C	An octomeric protein complex having creatine kinase activity.
2188	translation reinitiation	P	A gene-specific translational control mechanism where the small ribosomal subunit remains attached to the mRNA following termination of translation, then resumes scanning on the same mRNA molecule and initiates again at a downstream start site. Reinitiation depends on de novo recruitment of the ternary complex that is required to recognize the next AUG codon.
2189	ribose phosphate diphosphokinase complex	C	A protein complex having ribose phosphate diphosphokinase activity.
2190	cap-independent translational initiation	P	The process where translation initiation recruits the 40S ribosomal subunits in a Cap and 5' end independent fashion before an AUG codon is encountered in an appropriate sequence context to initiate mRNA translation.
2191	cap-dependent translational initiation	P	The process where the "Cap structure" (composed of a 7- methylguanosine (m7G) group and associated cap-binding proteins) located at the 5' end of an mRNA molecule, which serves as a "molecular tag" that marks the spot where the 40S ribosomal subunit is recruited and will then scan in a 5' to 3' direction until an AUG codon is encountered in an appropriate sequence context to initiate mRNA translation.
2192	IRES-dependent translational initiation	P	The process where translation initiation recruits the 40S ribosomal subunits via an internal ribosome entry segment (IRES) before an AUG codon is encountered in an appropriate sequence context to initiate mRNA translation.
2193	MAML1-RBP-Jkappa- ICN1 complex	C	A protein complex that consists of the intracellular domain of Notch1 (ICN1), the DNA-binding transcription factor RBP-Jkappa, and the transcriptional coactivator Mastermind-like-1 (MAML1); the complex is involved in transcriptional activation in response to Notch-mediated signaling.
2194	hepatocyte cell migration	P	The orderly movement of a hepatocyte during the development of the liver. Hepatocytes emerge from the hepatic epithelium, populating the septum transversum and lateral mesenchymal areas of the hepatic lobes.
2195	2-methylthio-N-6-(cis-hydroxy)isopentenyl adenosine-tRNA biosynthesis	P	The chemical reactions and pathways involved in the biosynthesis of 2-methylthio-N-6-(cis-hydroxy)isopentenyl adenosine (ms2io6A), a modified nucleoside present in position 37 (adjacent to and 3' of the anticodon) of tRNAs.
2196	Ser-tRNA(Ala) hydrolase activity	F	Catalysis of the hydrolysis of misacylated Ser-tRNA(Ala).
2197	xanthine dehydrogenase complex	C	A homodimeric protein complex having xanthine dehydrogenase activity.
2199	zona pellucida receptor complex	C	A multisubunit complex comprising the chaperonin-containing T-complex and several other components involved in mediating sperm-oocyte Interaction.
2200	somatic diversification of immune receptors	P	The somatic process allowing for the production of immune receptors whose specificity is not encoded in the germline genomic sequences.
2201	somatic diversification of DSCAM-based immune receptors	P	The somatic process that results in the generation of sequence diversity of the DSCAM-based immune receptors of insects.
2202	somatic diversification of variable lymphocyte receptors of jawless fish	P	The somatic process that results in the generation of sequence diversity of the variable lymphocyte receptors (VLR) of jawless fish.
2203	proteolysis by cytosolic proteases associated with antigen processing and presentation	P	The hydrolysis of a peptide bond or bonds within a protein by cytosolic resident proteases during antigen processing and presentation.
2204	somatic recombination of immunoglobulin genes involved in immune response	P	The process in which immunoglobulin genes are formed through recombination of the germline genetic elements, also known as immunoglobulin gene segments, within a single locus following the induction of and contributing to an immune response.
2205	somatic hypermutation of immunoglobulin genes involved in immune response	P	Mutations occurring somatically that result in amino acid changes in the rearranged V regions of immunoglobulins following the induction of and contributing to an immune response.
2206	gene conversion of immunoglobulin genes	P	The somatic process in which immunoglobulin genes are diversified through the mechanism of gene conversion.
2207	gene conversion of immunoglobulin genes involved in immune response	P	The somatic process in which immunoglobulin genes are diversified through the mechanism of gene conversion following the induction of and contributing to an immune response.
2208	somatic diversification of immunoglobulins involved in immune response	P	The somatic process that results in the generation of sequence diversity of immunoglobulins after induction, and contributes to an immune response.
2209	behavioral defense response	P	A behavioral response seeking to protect an organism from an a perceived external threat to that organism.
2210	behavioral response to wounding	P	A behavioral response resulting from wounding.
2211	behavioral defense response to insect	P	A behavioral response seeking to protect an organism from an a perceived external threat from an insect or insects to that organism.
2212	behavioral defense response to nematode	P	A behavioral response seeking to protect an organism from an a perceived external threat from a nematode or nematodes to that organism.
2213	defense response to insect	P	A response to protect an organism from a directly detected or perceived external threat from an insect or insects to that organism.
2215	defense response to nematode	P	A response to protect an organism from a directly detected or perceived external threat from a nematode or nematodes, which results in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack.
2218	activation of innate immune response	P	Any process that initiates an innate immune response. Innate immune responses are defense responses mediated by germline encoded components that directly recognize components of potential pathogens. Examples of this process include activation of the hypersensitive response of Arabidopsis thaliana and activation of any NOD or TLR signaling pathway in vertebrate species.
2220	innate immune response activating cell surface receptor signaling pathway	P	Any series of molecular signals leading to activation of the innate immune response generated as a consequence of binding to a cell surface receptor.
2221	pattern recognition receptor signaling pathway	P	Any series of molecular signals generated as a consequence of a pattern recognition receptor (PRR) binding to one of its physiological ligands. PRRs bind pathogen-associated molecular pattern (PAMPs), structures conserved among microbial species, or damage-associated molecular pattern (DAMPs), endogenous molecules released from damaged cells.
2222	stimulatory killer cell immunoglobulin-like receptor signaling pathway	P	Any series of molecular signals generated as a consequence of binding to a killer cell immunoglobulin-like receptor capable of cellular activation.
2223	stimulatory C-type lectin receptor signaling pathway	P	Any series of molecular signals generated as a consequence of binding to a C-type lectin receptor capable of cellular activation.
2224	toll-like receptor signaling pathway	P	Any series of molecular signals generated as a consequence of binding to a toll-like receptor. Toll-like receptors directly bind pattern motifs from a variety of microbial sources to initiate innate immune response.
2225	positive regulation of antimicrobial peptide production	P	Any process that activates or increases the frequency, rate, or extent of antimicrobial peptide production.
2227	innate immune response in mucosa	P	Any process of the innate immune response that takes place in the mucosal tissues.
2228	natural killer cell mediated immunity	P	The promotion of an immune response by natural killer cells through direct recognition of target cells or through the release of cytokines.
2229	defense response to oomycetes	P	Reactions triggered in response to the presence of oomycetes that act to protect the cell or organism.
2230	positive regulation of defense response to virus by host	P	Any host process that results in the promotion of antiviral immune response mechanisms, thereby limiting viral replication.
2231	detection of oomycetes	P	The series of events in which a stimulus from an oomycetes is received and converted into a molecular signal.
2232	leukocyte chemotaxis involved in inflammatory response	P	The movement of an immune cell in response to an external stimulus contributing to an inflammatory response.
2233	leukocyte chemotaxis involved in immune response	P	The movement of an immune cell in response to an external stimulus a part of an immune response.
2234	detection of endoplasmic reticulum overloading	P	The series of events in which a stimulus generated by the accumulation of normal or misfolded proteins in the endoplasmic reticulum is received and converted into a molecular signal.
2235	detection of unfolded protein	P	The series of events in which an unfolded protein stimulus is received and converted into a molecular signal.
2236	detection of misfolded protein	P	The series of events in which a misfolded protein stimulus is received and converted into a molecular signal.
2237	response to molecule of bacterial origin	P	Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by molecules of bacterial origin such as peptides derived from bacterial flagellin.
2238	response to molecule of fungal origin	P	Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by molecules of fungal origin such as chito-octamer oligosaccharide.
2239	response to oomycetes	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from an oomycetes.
2240	response to molecule of oomycetes origin	P	Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by molecules of oomycetes origin.
2241	response to parasitic plant	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a parasitic plant.
2242	defense response to parasitic plant	P	Reactions triggered in response to the presence of a parasitic plant that act to protect an organism.
2243	detection of parasitic plant	P	The series of events in which a stimulus from a parasitic plant is received and converted into a molecular signal.
2244	hematopoietic progenitor cell differentiation	P	The process in which precursor cell type acquires the specialized features of a hematopoietic progenitor cell, a class of cell types including myeloid progenitor cells and lymphoid progenitor cells.
2246	wound healing involved in inflammatory response	P	The series of events that restore integrity to damaged tissue that contribute to an inflammatory response.
2247	clearance of damaged tissue involved in inflammatory response wound healing	P	The series of events leading to removal of necrotic debris that contribute to an inflammatory response.
2248	connective tissue replacement involved in inflammatory response wound healing	P	The series of events leading to growth of connective tissue when loss of tissues that are incapable of regeneration occurs, or when fibrinous exudate cannot be adequately cleared that contribute to an inflammatory response.
2249	lymphocyte anergy	P	Any process contributing to lymphocyte anergy, a state of functional inactivation.
2250	adaptive immune response	P	An immune response mediated by cells expressing specific receptors for antigen produced through a somatic diversification process, and allowing for an enhanced secondary response to subsequent exposures to the same antigen (immunological memory).
2251	organ or tissue specific immune response	P	An immune response taking place in an organ or tissues such as the liver, brain, mucosa, or nervous system tissues.
2252	immune effector process	P	Any process of the immune system that can potentially contribute to an immune response.
2253	activation of immune response	P	Any process that initiates an immune response.
2254	kinin cascade	P	A series of reactions that takes place outside the cell that occur as a result of by-products of tissue damage, including collagen, cartilage, and basement membrane. The ultimate product of the kinin cascade include kallidin and bradykinin, agents known to induce smooth muscle contraction, vasoconstriction, and increased vascular permeability.
2255	tissue kallikrein-kinin cascade	P	A series of reactions that takes place outside the cell initiated by the action of tissue (glandular) kallikreins on low molecular weight kininogen in response to tissue damage. Tissue kallikreins are present in glandular tissues and their fluids, such as the salivary glands, sweat glands, pancreas, and kidney. The ultimate products of the tissue kallikrein-kinin cascade include kallidin and bradykinin, agents known to induce smooth muscle contraction, vasoconstriction, and increased vascular permeability.
2256	regulation of kinin cascade	P	Any process that modulates the frequency, rate, or extent of the kinin cascade.
2257	negative regulation of kinin cascade	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of the kinin cascade.
2258	positive regulation of kinin cascade	P	Any process that activates or increases the frequency, rate, or extent of the kinin cascade.
2259	endothelial cell activation within high endothelial venule involved in immune response	P	A change in the morphology or behavior of an endothelial cell within a high endothelial venule resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response.
2260	lymphocyte homeostasis	P	The process of regulating the proliferation and elimination of lymphocytes such that the total number of lymphocytes within a whole or part of an organism is stable over time in the absence of an outside stimulus.
2261	mucosal lymphocyte homeostasis	P	The process of regulating the proliferation and elimination of lymphocytes such that the total number of lymphocytes within the mucosal tissue of an organism is stable over time in the absence of an outside stimulus.
2262	myeloid cell homeostasis	P	The process of regulating the proliferation and elimination of myeloid cells such that the total number of myeloid cells within a whole or part of an organism is stable over time in the absence of an outside stimulus.
2263	cell activation involved in immune response	P	A change in the morphology or behavior of a cell resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response.
2264	endothelial cell activation involved in immune response	P	A change in the morphology or behavior of an endothelial cell resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response.
2265	astrocyte activation involved in immune response	P	A change in the morphology or behavior of an astrocyte resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response.
2266	follicular dendritic cell activation	P	A change in the morphology or behavior of a follicular dendritic cell resulting from exposure to an activating factor such as a cellular or soluble ligand.
2267	follicular dendritic cell activation involved in immune response	P	A change in the morphology or behavior of a follicular dendritic cell resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response.
2268	follicular dendritic cell differentiation	P	The process in which a relatively unspecialized precursor cell acquires the specialized features of a follicular dendritic cell.
2269	leukocyte activation involved in inflammatory response	P	A change in the morphology or behavior of a leukocyte resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an inflammatory response.
2270	plasmacytoid dendritic cell activation	P	A change in the morphology or behavior of a plasmacytoid dendritic cell resulting from exposure to an activating factor such as a cellular or soluble ligand.
2271	plasmacytoid dendritic cell activation involved in immune response	P	A change in the morphology or behavior of a plasmacytoid dendritic cell resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response.
2272	plasmacytoid dendritic cell differentiation involved in immune response	P	The process in which an immature plasmacytoid dendritic cell acquires the specialized features of a mature plasmacytoid dendritic cell contributing to an immune response.
2273	plasmacytoid dendritic cell differentiation	P	The process in which a relatively unspecialized hemopoietic precursor cell acquires the specialized features of a plasmacytoid dendritic cell.
2274	myeloid leukocyte activation	P	A change in the morphology or behavior of a myeloid leukocyte resulting from exposure to an activating factor such as a cellular or soluble ligand.
2275	myeloid cell activation involved in immune response	P	A change in the morphology or behavior of a myeloid cell resulting from exposure to an activating factor such as a cellular or soluble ligand, leading to the initiation or perpetuation of an immune response.
2276	basophil activation involved in immune response	P	A change in morphology and behavior of a basophil resulting from exposure to a cytokine, chemokine, soluble factor, or to (at least in mammals) an antigen which the basophil has specifically bound via IgE bound to Fc-epsilonRI receptors, leading to the initiation or perpetuation of an immune response.
2277	myeloid dendritic cell activation involved in immune response	P	The change in morphology and behavior of a myeloid dendritic cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response.
2278	eosinophil activation involved in immune response	P	The change in morphology and behavior of a eosinophil resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response.
2279	mast cell activation involved in immune response	P	The change in morphology and behavior of a mast cell resulting from exposure to a cytokine, chemokine, soluble factor, or to (at least in mammals) an antigen which the mast cell has specifically bound via IgE bound to Fc-epsilonRI receptors, leading to the initiation or perpetuation of an immune response.
2280	monocyte activation involved in immune response	P	The change in morphology and behavior of a monocyte resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response.
2281	macrophage activation involved in immune response	P	A change in morphology and behavior of a macrophage resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response.
2282	microglial cell activation involved in immune response	P	The change in morphology and behavior of a microglial cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response.
2283	neutrophil activation involved in immune response	P	The change in morphology and behavior of a neutrophil resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response.
2284	myeloid dendritic cell differentiation involved in immune response	P	The process in which an immature myeloid dendritic cell acquires the specialized features of a mature myeloid dendritic cell as part of an immune response.
2285	lymphocyte activation involved in immune response	P	A change in morphology and behavior of a lymphocyte resulting from exposure to a specific antigen, mitogen, cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response.
2286	T cell activation involved in immune response	P	The change in morphology and behavior of a mature or immature T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific, leading to the initiation or perpetuation of an immune response.
2287	alpha-beta T cell activation involved in immune response	P	The change in morphology and behavior of an alpha-beta T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific, leading to the initiation or perpetuation of an immune response.
2288	NK T cell activation involved in immune response	P	The change in morphology and behavior of a mature or immature natural killer T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific, leading to the initiation or perpetuation of an immune response.
2289	NK T cell proliferation involved in immune response	P	The expansion of a NK T cell population by cell division as part of an immune response.
2290	gamma-delta T cell activation involved in immune response	P	The change in morphology and behavior of a gamma-delta T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific, leading to the initiation or perpetuation of an immune response.
2291	T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell	P	The change in morphology and behavior of a mature or immature T cell resulting from exposure to an antigen for which its T cell receptor is specific bound to an MHC molecule on an antigen presenting cell, leading to the initiation or perpetuation of an immune response.
2292	T cell differentiation involved in immune response	P	The process in which an antigenically naive T cell acquires the specialized features of an effector, regulatory, or memory T cell as part of an immune response. Effector T cells include cells which provide T cell help or exhibit cytotoxicity towards other cells.
2293	alpha-beta T cell differentiation involved in immune response	P	The process in which an antigenically naive alpha-beta T cell acquires the specialized features of an effector, regulatory, or memory T cell during an immune response. Effector T cells include cells which provide T cell help or exhibit cytotoxicity towards other cells.
2294	CD4-positive, alpha-beta T cell differentiation involved in immune response	P	The process in which an antigenically naive CD4-positive, alpha-beta T cell acquires the specialized features of an effector, regulatory, or memory T cell as part of an immune response. Effector T cells include cells which provide T cell help or exhibit cytotoxicity towards other cells.
2295	T-helper cell lineage commitment	P	The process in which a CD4-positive, alpha-beta T cell becomes committed to becoming a T-helper cell, a CD4-positive, alpha-beta T cell specialized to promote various immunological processes.
2296	T-helper 1 cell lineage commitment	P	The process in which a CD4-positive, alpha-beta T cell becomes committed to becoming a T-helper 1 cell, a CD4-positive, alpha-beta T cell specialized to promote immunological processes often associated with resistance to intracellular bacteria, fungi, and protozoa, and pathological conditions such as arthritis.
2297	T-helper 2 cell lineage commitment	P	The process in which a CD4-positive, alpha-beta T cell becomes committed to becoming a T-helper 2 cell, a CD4-positive, alpha-beta T cell specialized to promote immunological processes often associated with resistance to extracellular organisms such as helminths, enhanced production of particular antibody isotypes, and pathological conditions such as allergy.
2298	CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response	P	The process in which an antigenically naive CD4-positive, alpha-beta T cell acquires the specialized features of a CD4-positive, CD25-positive, alpha-beta regulatory T cell as part of an immune response.
2299	alpha-beta intraepithelial T cell differentiation	P	The process in which a precursor cell type acquires the specialized features of an alpha-beta intraepithelial T cell. Intraepithelial T cells are found among epithelial cells in mucosal areas and have distinct phenotypes and developmental pathways.
2300	CD8-positive, alpha-beta intraepithelial T cell differentiation	P	The process in which a precursor cell type acquires the specialized features of a CD8-positive, alpha-beta intraepithelial T cell. Intraepithelial T cells are found among epithelial cells in mucosal areas and have distinct phenotypes and developmental pathways.
2301	CD4-positive, alpha-beta intraepithelial T cell differentiation	P	The process in which a precursor cell type acquires the specialized features of a CD4-positive, alpha-beta intraepithelial T cell. Intraepithelial T cells are found among epithelial cells in mucosal areas and have distinct phenotypes and developmental pathways.
2302	CD8-positive, alpha-beta T cell differentiation involved in immune response	P	The process in which an antigenically naive CD8-positive, alpha-beta T cell acquires the specialized features of an effector, regulatory, or memory T cell as part of an immune response. Effector T cells include cells which provide T cell help or exhibit cytotoxicity towards other cells.
2303	gamma-delta T cell differentiation involved in immune response	P	The process in which an antigenically naive gamma-delta T cell acquires the specialized features of an effector, regulatory, or memory T cell and contributes to an immune response. Effector T cells include cells which provide T cell help or exhibit cytotoxicity towards other cells.
2304	gamma-delta intraepithelial T cell differentiation	P	The process in which a precursor cell type acquires the specialized features of a gamma-delta intraepithelial T cell. Intraepithelial T cells are found among epithelial cells in mucosal areas and have distinct phenotypes and developmental pathways.
2305	CD8-positive, gamma-delta intraepithelial T cell differentiation	P	The process in which a precursor cell type acquires the specialized features of a CD8-positive, gamma-delta intraepithelial T cell. Intraepithelial T cells are found among epithelial cells in mucosal areas and have distinct phenotypes and developmental pathways.
2306	CD4-positive gamma-delta intraepithelial T cell differentiation	P	The process in which a precursor cell type acquires the specialized features of a CD4-positive, gamma-delta intraepithelial T cell. Intraepithelial T cells are found among epithelial cells in mucosal areas and have distinct phenotypes and developmental pathways.
2307	CD8-positive, alpha-beta regulatory T cell differentiation	P	The process in which a precursor cell type acquires the specialized features of a CD8-positive, alpha-beta regulatory T cell.
2308	CD8-positive, alpha-beta cytotoxic T cell differentiation	P	The process in which a precursor cell type acquires the specialized features of a CD8-positive, alpha-beta cytotoxic T cell.
2309	T cell proliferation involved in immune response	P	The expansion of a T cell population by cell division as part of an immune response.
2310	alpha-beta T cell proliferation involved in immune response	P	The expansion of an alpha-beta T cell population by cell division as part of an immune response.
2311	gamma-delta T cell proliferation involved in immune response	P	The expansion of a gamma-delta T cell population by cell division as part of an immune response.
2312	B cell activation involved in immune response	P	The change in morphology and behavior of a mature or immature B cell during an immune response, resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.
2313	mature B cell differentiation involved in immune response	P	The process in which a naive B cell acquires the specialized features of a mature or memory B cell during an immune response.
2314	germinal center B cell differentiation	P	The process in which a B cell in the spleen acquires the specialized features of a germinal center B cell. Germinal center B cells are rapidly cycling B cells which have downregulated IgD expression and exhibit high levels of binding by peanut agglutinin (PNA).
2315	marginal zone B cell differentiation	P	The process in which a B cell in the spleen acquires the specialized features of a marginal zone B cell. Marginal zone B cells are localized in a distinct anatomical region of the spleen that represents the major antigen-filtering and scavenging area (by specialized macrophages resident there). It appears that they are preselected to express a BCR repertoire similar to B-1 B cells, biased toward bacterial cell wall constituents and senescent self-components (such as oxidized LDL).
2316	follicular B cell differentiation	P	The process in which a B cell in the spleen acquires the specialized features of a follicular B cell. Follicular B cells are major population of mature recirculating B cells in the spleen and are located in the B-cell follicle region.
2317	plasma cell differentiation	P	The process in which a B cell acquires the specialized features of a plasma cell. A plasma cell is a lymphocyte which develops from a B cell and produces high amounts of antibody.
2318	myeloid progenitor cell differentiation	P	The process in which a precursor cell type acquires the specialized features of a myeloid progenitor cell. Myeloid progenitor cells include progenitor cells for any of the myeloid lineages.
2319	memory B cell differentiation	P	The process in which a B cell acquires the specialized features of a memory B cell. Memory B cells are cells that can respond rapidly to antigen re-exposure by production of high-affinity antibody.
2320	lymphoid progenitor cell differentiation	P	The process in which a precursor cell type acquires the specialized features of a lymphoid progenitor cell. Lymphoid progenitor cells include progenitor cells for any of the lymphoid lineages.
2321	natural killer cell progenitor differentiation	P	The process in which a precursor cell type acquires the specialized features of a natural killer cell progenitor.
2322	B cell proliferation involved in immune response	P	The expansion of a B cell population by cell division following B cell activation during an immune response.
2323	natural killer cell activation involved in immune response	P	The change in morphology and behavior of a natural killer cell resulting from exposure a cytokine, chemokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response.
2324	natural killer cell proliferation involved in immune response	P	The expansion of a natural killer cell population by cell division as part of an immune response.
2325	natural killer cell differentiation involved in immune response	P	The process in which a naive natural killer cell acquires the specialized features of an effector natural killer T cell as part of an immune response.
2326	B cell lineage commitment	P	The process in which a lymphoid progenitor cell becomes committed to become any type of B cell.
2327	immature B cell differentiation	P	The process in which a precursor cell type acquires the specialized features of an immature B cell.
2328	pro-B cell differentiation	P	The process in which a precursor cell type acquires the specialized features of a pro-B cell. Pro-B cells are the earliest stage of the B cell lineage and undergo heavy chain D and J gene rearrangements, although they are not fully committed.
2329	pre-B cell differentiation	P	The process in which a precursor cell type acquires the specialized features of a pre-B cell. Pre-B cells follow the pro-B cell stage of immature B cell differentiation and undergo rearrangement of heavy chain V, D, and J gene segments.
2330	pre-B cell receptor expression	P	The process leading up to expression of the pre-B cell receptor on the surface of pre-B cells, including expression of the surrogate light chain, association of the surrogate light chain with heavy chain, and expression of the complete pre-B cell receptor on the cell surface.
2331	pre-B cell allelic exclusion	P	Expression of a single heavy chain allele during pre-B cell differentiation.
2332	transitional stage B cell differentiation	P	The process in which immature B cells from the bone marrow become mature B cells in the spleen. Transitional stage B cells are subdivided into transitional one (T1) and transitional two (T2) stages and are short-lived and functionally incompetent.
2333	transitional one stage B cell differentiation	P	The process in which immature B cells from the bone marrow acquire the specialized features of T1 stage B cells in the spleen. T1 stage B cells do not express either CD23 or CD21.
2334	transitional two stage B cell differentiation	P	The process in which immature B cells from the bone marrow acquire the specialized features of T2 stage B cells in the spleen. T2 stage B cells express CD23 but not CD21.
2335	mature B cell differentiation	P	The process in which transitional stage B cells acquire the specialized features of mature B cells in the spleen.
2336	B-1 B cell lineage commitment	P	The process in which an immature B cell becomes committed to become a B-1 B cell.
2337	B-1a B cell differentiation	P	The process in which B cells acquire the specialized features of B-1a B cells. B-1a B cells are B-1 cells that express CD5 and arise from fetal liver precursors.
2338	B-1b B cell differentiation	P	The process in which B cells acquire the specialized features of B-1b B cells. B-1b B cells are B-1 cells that do not express CD5.
2339	B cell selection	P	The process dependent upon B cell antigen receptor signaling in response to self or foreign antigen through which B cells are selected for survival.
2340	central B cell selection	P	Any B cell selection process that occurs in the bone marrow.
2341	central B cell anergy	P	Any process contributing to anergy, a state of functional inactivation that occurs as part of tolerance induction, in B cells in the bone marrow.
2342	central B cell deletion	P	The deletion of B cells by apoptotic process occurring as part of central tolerance induction and B cell selection.
2343	peripheral B cell selection	P	Any B cell selection process that occurs in the periphery.
2344	B cell affinity maturation	P	The process in which B cells produce antibodies with increased antigen affinity. This is accomplished by somatic hypermutation and selection for B cells which produce higher affinity antibodies to antigen.
2345	peripheral B cell receptor editing	P	The process that takes place mainly in germinal center B cells in which a large number of mutations are generated in the heavy chain and light chain V-region genes and their immediately surrounding introns in order to increase antibody diversity and contribute to affinity maturation.
2346	B cell positive selection	P	Any process in which B cells are selected to survive based on signaling through the B cell antigen receptor.
2347	response to tumor cell	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a tumor cell.
2348	central B cell positive selection	P	Any process leading to positive selection of B cells in the bone marrow. Positive selection is the process in which B or T cells are selected to survive based on signaling through their antigen receptors.
2349	histamine production involved in inflammatory response	P	The synthesis or release of histamine following a stimulus as part of an inflammatory response, resulting in an increase in its intracellular or extracellular levels.
2350	peripheral B cell positive selection	P	Any process leading to positive selection of B cells in the periphery. Positive selection is the process in which B or T cells are selected to survive based on signaling through their antigen receptors.
2351	serotonin production involved in inflammatory response	P	The synthesis or release of serotonin following a stimulus as part of an inflammatory response, resulting in an increase in its intracellular or extracellular levels.
2352	B cell negative selection	P	Any process leading to negative selection in B cells. Mechanisms of negative selection include anergy and deletion.
2353	plasma kallikrein-kinin cascade	P	A series of reactions that takes place outside the cell occurring in response to tissue damage and initiated within blood plasma by the action of activated Factor XII (Hageman Factor) on prekallikrein to convert it to plasma kallikrein, and the subsequent reaction of plasma kallikrein with high molecular weight kininogen. The ultimate product of the plasma kallikrein-kinin cascade is bradykinin, an agent known to induce smooth muscle contraction, vasoconstriction, and increased vascular permeability.
2354	central B cell negative selection	P	Any process leading to negative selection of B cells in the bone marrow.
2355	detection of tumor cell	P	The series of events in which a stimulus from a tumor cell is received and converted into a molecular signal.
2356	peripheral B cell negative selection	P	Any process leading to negative selection of B cells in the periphery.
2357	defense response to tumor cell	P	Reactions triggered in response to the presence of a tumor cell that act to protect the cell or organism.
2358	B cell homeostatic proliferation	P	The non-specific expansion of B cell populations within a whole or part of an organism to reach to a total number of B cells which will then remain stable over time in the absence of an external stimulus.
2359	B-1 B cell proliferation	P	The expansion of a B-1 B cell by cell division. Follows B cell activation.
2360	T cell lineage commitment	P	The process in which a lymphoid progenitor cell becomes committed to becoming any type of T cell.
2361	CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation	P	The process in which a precursor cell type acquires the specialized features of a CD4-positive, CD25-positive, alpha-beta regulatory T cell.
2362	CD4-positive, CD25-positive, alpha-beta regulatory T cell lineage commitment	P	The process in which a CD4-positive, alpha-beta T cell becomes committed to becoming a CD4-positive, CD25-positive, alpha-beta regulatory T cell.
2363	alpha-beta T cell lineage commitment	P	The process in which a pro-T cell becomes committed to becoming an alpha-beta T cell.
2364	NK T cell lineage commitment	P	The process in which a pro-T cell becomes committed to becoming an NK T cell.
2365	gamma-delta T cell lineage commitment	P	The process in which a pro-T cell becomes committed to becoming a gamma-delta T cell.
2366	leukocyte activation involved in immune response	P	A change in morphology and behavior of a leukocyte resulting from exposure to a specific antigen, mitogen, cytokine, cellular ligand, or soluble factor, leading to the initiation or perpetuation of an immune response.
2367	cytokine production involved in immune response	P	The appearance of a cytokine due to biosynthesis or secretion following a cellular stimulus contributing to an immune response, resulting in an increase in its intracellular or extracellular levels.
2368	B cell cytokine production	P	Any process that contributes to cytokine production by a B cell.
2369	T cell cytokine production	P	Any process that contributes to cytokine production by a T cell.
2370	natural killer cell cytokine production	P	Any process that contributes to cytokine production by a natural killer cell.
2371	dendritic cell cytokine production	P	Any process that contributes to cytokine production by a dendritic cell.
2372	myeloid dendritic cell cytokine production	P	Any process that contributes to cytokine production by a myeloid dendritic cell.
2373	plasmacytoid dendritic cell cytokine production	P	Any process that contributes to cytokine production by a plasmacytoid dendritic cell.
2374	cytokine secretion involved in immune response	P	The regulated release of cytokines from a cell that contributes to an immune response.
2375	cytokine biosynthetic process involved in immune response	P	The chemical reactions and pathways resulting in the formation of a cytokine that contributes to an immune response.
2376	immune system process	P	Any process involved in the development or functioning of the immune system, an organismal system for calibrated responses to potential internal or invasive threats.
2377	immunoglobulin production	P	The appearance of immunoglobulin due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
2378	immunoglobulin biosynthetic process	P	The chemical reactions and pathways resulting in the formation of immunoglobulin.
2379	immunoglobulin biosynthetic process involved in immune response	P	The chemical reactions and pathways resulting in the formation of immunoglobulin contributing to an immune response.
2380	immunoglobulin secretion involved in immune response	P	The regulated release of immunoglobulins from a B cell or plasma cell contributing to an immune response.
2381	immunoglobulin production involved in immunoglobulin mediated immune response	P	The appearance of immunoglobulin due to biosynthesis or secretion following a cellular stimulus during an immune response, resulting in an increase in its intracellular or extracellular levels.
2382	regulation of tissue kallikrein-kinin cascade	P	Any process that modulates the frequency, rate, or extent of the tissue kallikrein-kinin cascade.
2383	immune response in brain or nervous system	P	An immune response taking place in the brain or nervous system.
2384	hepatic immune response	P	An immune response taking place in the liver.
2385	mucosal immune response	P	An immune response taking place in mucosal tissues, including those of the intestinal tract, nasal and upper respiratory tract, and genital tract.
2386	immune response in mucosal-associated lymphoid tissue	P	Immune response taking place in the mucosal-associated lymphoid tissue (MALT). Mucosal-associated lymphoid tissue is typically found as nodules associated with mucosal epithelia with distinct internal structures including B- and T-zones for the activation of lymphocytes.
2387	immune response in gut-associated lymphoid tissue	P	Immune response taking place in the gut-associated lymphoid tissue (GALT). GALT includes Peyer's patches, appendix, and solitary lymph nodules.
2388	immune response in Peyer's patch	P	Immune response taking place in the Peyer's patch, nodular lymphoid structures on the serosal surface of the small intestine.
2389	tolerance induction in Peyer's patch	P	Tolerance induction taking place in the Peyer's patches.
2390	platelet activating factor production	P	The synthesis or release of platelet activating factor following a stimulus, resulting in an increase in its intracellular or extracellular levels.
2391	platelet activating factor production involved in inflammatory response	P	The synthesis or release of platelet activating factor following a stimulus as part of an inflammatory response, resulting in an increase in its intracellular or extracellular levels.
2392	platelet activating factor secretion	P	The regulated release of platelet activating factor by a cell.
2393	lysosomal enzyme production involved in inflammatory response	P	The synthesis or release of lysosomal enzymes following a stimulus as part of a inflammatory response, resulting in an increase in intracellular or extracellular levels.
2394	tolerance induction in gut-associated lymphoid tissue	P	Tolerance induction taking place in the gut-associated lymphoid tissue (GALT).
2395	immune response in nasopharyngeal-associated lymphoid tissue	P	An immune response taking place in the nasopharyngeal-associated lymphoid tissue (NALT). NALT includes the tonsils and adenoids.
2396	MHC protein complex assembly	P	The aggregation, arrangement and bonding together of a set of components to form an MHC protein complex.
2397	MHC class I protein complex assembly	P	The aggregation, arrangement and bonding together of a set of components to form an MHC class I protein complex. Class I here refers to classical class I molecules.
2398	MHC class Ib protein complex assembly	P	The aggregation, arrangement and bonding together of a set of components to form an MHC class Ib protein complex. Class Ib here refers to non-classical class I molecules.
2399	MHC class II protein complex assembly	P	The aggregation, arrangement and bonding together of a set of components to form an MHC class II protein complex.
2400	tolerance induction in nasopharyngeal-associated lymphoid tissue	P	Tolerance induction taking place in the nasopharyngeal-associated lymphoid tissue (NALT).
2401	tolerance induction in mucosal-associated lymphoid tissue	P	Tolerance induction taking place in the mucosal-associated lymphoid tissue (MALT).
2402	B cell tolerance induction in mucosal-associated lymphoid tissue	P	Tolerance induction taking place in the mucosal-associated lymphoid tissue (MALT) mediated by B cells.
2403	T cell tolerance induction in mucosal-associated lymphoid tissue	P	Tolerance induction taking place in the mucosal-associated lymphoid tissue (MALT) mediated by T cells.
2404	antigen sampling in mucosal-associated lymphoid tissue	P	The process of apical-to-basolateral delivery of soluble and particulate antigens to underlying mucosal-associated lymphoid tissue.
2405	antigen sampling by dendritic cells in mucosal-associated lymphoid tissue	P	The process of antigen sampling carried out by dendritic cells in the mucosal-associated lymphoid tissue.
2406	antigen sampling by M cells in mucosal-associated lymphoid tissue	P	The process of antigen samples carried out by M cells in the mucosal-associated lymphoid tissue.
2407	dendritic cell chemotaxis	P	The movement of a dendritic cell in response to an external stimulus.
2408	myeloid dendritic cell chemotaxis	P	The movement of a myeloid dendritic cell in response to an external stimulus.
2409	Langerhans cell chemotaxis	P	The movement of a Langerhans cell in response to an external stimulus.
2410	plasmacytoid dendritic cell chemotaxis	P	The movement of a plasmacytoid dendritic cell in response to an external stimulus.
2411	T cell tolerance induction to tumor cell	P	A process of tolerance induction dependent on T cells which leads to immunological tolerance of a tumor.
2412	antigen transcytosis by M cells in mucosal-associated lymphoid tissue	P	The process of antigen transcytosis carried out by M cells in the mucosal-associated lymphoid tissue (MALT). Transcytosis is the process of the directed movement of endocytosed material through the cell and its exocytosis from the plasma membrane at the opposite side. M cells are specialized epithelia cells with a microfold structure that are adept at moving antigens from the gut lumen to antigen presenting cells in the MALT.
2413	tolerance induction to tumor cell	P	A process of tolerance induction which leads to immunological tolerance of a tumor.
2414	immunoglobulin transcytosis in epithelial cells	P	The process of transporting immunoglobulin, via transcytosis, from one side of an epithelial cell to the other.
2415	immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor	P	The process of transporting polymeric IgA and polymeric IgM immunoglobulin, via transcytosis mediated by the polymeric immunoglobulin receptor (pIgR), from the basolateral surface to apical surface of an epithelial cell. At the apical surface the immunoglobulin binding portion of the pIgRis cleaved and remains bound to the transported immunoglobulin as secretory component (SC). The same process is used for the transport and excretion of IgA immune complexes to the luminal surface of the mucosa.
2416	IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor	P	The process of transporting IgG immunoglobulin, via transcytosis using the FcRn (also known as the neonatal Fc receptor; gene name FCGRT), from apical surface of an epithelial cell to the basolateral surface or vice versa depending on the location. This process is used for uptake of IgG from the milk in the gut in rodents, for transplacental transport of IgG from mother to embryo in humans, and for maintenance of a steady-state distribution of IgG across epithelial boundaries in general in adult mammals.
2417	B cell antigen processing and presentation mediated by B cell receptor uptake of antigen	P	B cell antigen processing and presentation which is initiated by uptake of antigen bound to the B cell receptor.
2418	immune response to tumor cell	P	An immune system process that functions in the response of an organism to a tumor cell.
2419	T cell mediated cytotoxicity directed against tumor cell target	P	The directed killing of a tumor cell by a T cell through the release of granules containing cytotoxic mediators or through the engagement of death receptors.
2420	natural killer cell mediated cytotoxicity directed against tumor cell target	P	The directed killing of a tumor cell by a natural killer cell through the release of granules containing cytotoxic mediators or through the engagement of death receptors.
2421	B cell antigen processing and presentation following pinocytosis	P	B cell antigen processing and presentation which is initiated by uptake of antigen via pinocytosis.
2422	immune response in urogenital tract	P	An immune response taking place in the urogenital tract. The urogenital tract.
2423	natural killer cell mediated immune response to tumor cell	P	An immune response mediated by a natural killer cell triggered in response to the presence of a tumor cell.
2424	T cell mediated immune response to tumor cell	P	An immune response mediated by a T cell triggered in response to the presence of a tumor cell.
2425	tolerance induction in urogenital tract	P	Tolerance induction taking place in the urogenital tract.
2426	immunoglobulin production in mucosal tissue	P	The synthesis and release of immunoglobulin in the mucosal tissue.
2427	mucosal tolerance induction	P	Tolerance induction taking place in the mucosal tissues.
2428	antigen processing and presentation of peptide antigen via MHC class Ib	P	The process in which an antigen-presenting cell expresses peptide antigen in association with an MHC class Ib protein complex on its cell surface. The peptide antigen may originate from an endogenous or exogenous protein. Class Ib here refers to non-classical class I molecules, such as those of the HLA-E family.
2429	immune response-activating cell surface receptor signaling pathway	P	A series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of a cell capable of activating or perpetuating an immune response.
2430	complement receptor mediated signaling pathway	P	A series of molecular signals generated as a consequence of a component of the complement pathway binding to a complement receptor. Such components include both whole complement proteins and fragments of complement proteins generated through the activity of the complement pathway.
2431	Fc receptor mediated stimulatory signaling pathway	P	A series of molecular signals generated as a consequence of a the binding of the Fc portion of an immunoglobulin by an Fc receptor capable of activating or perpetuating an immune response. The Fc portion of an immunoglobulin is its C-terminal constant region.
2432	granuloma formation	P	The formation of nodular inflammatory lesions, usually small or granular, firm, persistent, well-structured, and containing compactly grouped T lymphocytes and modified phagocytes such as epithelioid cells, giant cells, and other macrophages. Granuloma formation represents a chronic inflammatory response initiated by various infectious and noninfectious agents. The center of a granuloma consists of fused macrophages, which can become necrotic.
2433	immune response-regulating cell surface receptor signaling pathway involved in phagocytosis	P	An immune response-regulating cell surface receptor signaling pathway that contributes to the endocytic engulfment of external particulate material by phagocytes.
2434	immune complex clearance	P	A process directed at removing immune complexes from the body. Immune complexes are clusters of antibodies bound to antigen, to which complement may also be fixed, and which may precipitate or remain in solution.
2435	immune complex clearance by erythrocytes	P	The process of immune complex clearance by erythrocytes.
2436	immune complex clearance by monocytes and macrophages	P	The process of immune complex clearance by monocytes or macrophages.
2437	inflammatory response to antigenic stimulus	P	An inflammatory response to an antigenic stimulus, which can be include any number of T cell or B cell epitopes.
2438	acute inflammatory response to antigenic stimulus	P	An acute inflammatory response to an antigenic stimulus. An acute inflammatory response occurs within a matter of minutes or hours, and either resolves within a few days or becomes a chronic inflammatory response.
2439	chronic inflammatory response to antigenic stimulus	P	A chronic inflammatory response to an antigenic stimulus. A chronic inflammatory response persists indefinitely during days, weeks, or months in the life of an individual.
2440	production of molecular mediator of immune response	P	The synthesis or release of any molecular mediator of the immune response, resulting in an increase in its intracellular or extracellular levels.
2441	histamine secretion involved in inflammatory response	P	The regulated release of histamine by a cell as part of an inflammatory response.
2442	serotonin secretion involved in inflammatory response	P	The regulated release of serotonin by a cell as part of an inflammatory response.
2443	leukocyte mediated immunity	P	Any process involved in the carrying out of an immune response by a leukocyte.
2444	myeloid leukocyte mediated immunity	P	Any process involved in the carrying out of an immune response by a myeloid leukocyte.
2445	type II hypersensitivity	P	An inflammatory response resulting in cell death or dysfunction mediated by activation of the classical complement pathway or induction of effector cell phagocytosis, cytolysis mechanisms via complement or Fc receptors following the binding of antibodies to cell surface antigens on a target cell, or mediated by the direct binding of antibody to cellular receptors.
2446	neutrophil mediated immunity	P	Any process involved in the carrying out of an immune response by a neutrophil.
2447	eosinophil mediated immunity	P	Any process involved in the carrying out of an immune response by an eosinophil.
2448	mast cell mediated immunity	P	Any process involved in the carrying out of an immune response by a mast cell.
2449	lymphocyte mediated immunity	P	Any process involved in the carrying out of an immune response by a lymphocyte.
2450	B cell antigen processing and presentation	P	The process in which a B cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex.
2451	peripheral B cell tolerance induction	P	Tolerance induction of mature B cells in the peripheral lymphoid tissues: the blood, lymph nodes, spleen, and mucosal-associated lymphoid tissue.
2452	B cell receptor editing	P	The process of replacing receptors on B cells, in which RAG gene expression allows continued light-chain gene rearrangement and expression of a new light change which combines with the previous heavy chain to form a new receptor.
2453	peripheral B cell anergy	P	Any process contributing to anergy, a state of functional inactivation that occurs as part of tolerance induction, in peripheral B cells.
2454	peripheral B cell deletion	P	The deletion of B cells by apoptotic process occurring as part of peripheral tolerance induction and B cell selection.
2455	humoral immune response mediated by circulating immunoglobulin	P	An immune response dependent upon secreted immunoglobulin. An example of this process is found in Mus musculus.
2456	T cell mediated immunity	P	Any process involved in the carrying out of an immune response by a T cell.
2457	T cell antigen processing and presentation	P	The process in which a T cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex.
2458	peripheral T cell tolerance induction	P	Tolerance induction of T cells in the periphery, in this case, any location in the body other than the thymus.
2459	adaptive immune response based on somatic recombination of immune receptors built from leucine-rich repeat domains	P	An immune response mediated by lymphocytes expressing specific receptors for antigen produced through a somatic diversification process that includes somatic recombination of variable lymphocyte receptors (VLR) incorporating leucine-rich repeat (LRR) domains, and allowing for enhanced responses upon subsequent exposures to the same antigen (immunological memory). Examples of this process are found in jawless fish, including the lampreys (Petromyzontidae) and hagfishes (Myxinidae).
2460	adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	P	An immune response mediated by lymphocytes expressing specific receptors for antigen produced through a somatic diversification process that includes somatic recombination of germline gene segments encoding immunoglobulin superfamily domains. Recombined receptors for antigen encoded by immunoglobulin superfamily domains include T cell receptors and immunoglobulins (antibodies) produced by B cells. The first encounter with antigen elicits a primary immune response that is slow and not of great magnitude. T and B cells selected by antigen become activated and undergo clonal expansion. A fraction of antigen-reactive T and B cells become memory cells, whereas others differentiate into effector cells. The memory cells generated during the primary response enable a much faster and stronger secondary immune response upon subsequent exposures to the same antigen (immunological memory). An example of this is the adaptive immune response found in Mus musculus.
2461	tolerance induction dependent upon immune response	P	Tolerance induction dependent upon an immune response, typically a response by a mature T or B cell in the periphery resulting tolerance towards an antigen via induction of anergy, cellular deletion, or regulatory T cell activation.
2462	tolerance induction to nonself antigen	P	Tolerance induction in response to nonself antigens.
2463	central tolerance induction to nonself antigen	P	Tolerance induction to nonself antigens in the central lymphoid organs.
2464	peripheral tolerance induction to nonself antigen	P	Tolerance induction to nonself antigens in the periphery.
2465	peripheral tolerance induction	P	Tolerance induction in the peripheral lymphoid tissues: blood, lymph nodes, spleen, and mucosal-associated lymphoid tissues.
2466	peripheral tolerance induction to self antigen	P	Tolerance induction to self antigens in the peripheral lymphoid tissues: blood, lymph nodes, spleen, and mucosal-associated lymphoid tissues.
2467	germinal center formation	P	The process in which germinal centers form. A germinal center is a specialized microenvironment formed when activated B cells enter lymphoid follicles. Germinal centers are the foci for B cell proliferation and somatic hypermutation.
2468	dendritic cell antigen processing and presentation	P	The process in which a dendritic cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex.
2469	myeloid dendritic cell antigen processing and presentation	P	The process in which a myeloid dendritic cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex.
2470	plasmacytoid dendritic cell antigen processing and presentation	P	The process in which a plasmacytoid dendritic cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex.
2471	monocyte antigen processing and presentation	P	The process in which a monocyte expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex.
2472	macrophage antigen processing and presentation	P	The process in which a macrophage expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex.
2473	non-professional antigen presenting cell antigen processing and presentation	P	The process in which a non-professional antigen presenting cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex. Non-professional antigen presenting cells include all cell types but dendritic cells, B cells, T cells, monocytes, macrophages, and neutrophils.
2474	antigen processing and presentation of peptide antigen via MHC class I	P	The process in which an antigen-presenting cell expresses a peptide antigen on its cell surface in association with an MHC class I protein complex. Class I here refers to classical class I molecules.
2475	antigen processing and presentation via MHC class Ib	P	The process in which an antigen-presenting cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC class Ib protein complex. Class Ib here refers to non-classical class I molecules, such as those of the CD1 or HLA-E gene families.
2476	antigen processing and presentation of endogenous peptide antigen via MHC class Ib	P	The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class Ib protein complex. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell. Class Ib here refers to non-classical class I molecules, such as those of the HLA-E gene family.
2477	antigen processing and presentation of exogenous peptide antigen via MHC class Ib	P	The process in which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC class Ib protein complex. The peptide is typically a fragment of a larger exogenous protein which has been degraded within the cell. Class Ib here refers to non-classical class I molecules, such as those of the HLA-E gene family.
2478	antigen processing and presentation of exogenous peptide antigen	P	The process in which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC protein complex. The peptide is typically a fragment of a larger exogenous protein which has been degraded within the cell.
2479	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent	P	The process in which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC class I protein complex following intracellular transport via a TAP (transporter associated with antigen processing) pathway. The peptide is typically a fragment of a larger exogenous protein which has been degraded within the cell and is dependent on TAP transport from the cytosol to ER for association with the MHC class I molecule. Class I here refers to classical class I molecules.
2480	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent	P	The process in which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC class I protein complex following intracellular transport via a pathway not requiring TAP (transporter associated with antigen processing). The peptide is typically a fragment of a larger exogenous protein which has been degraded within the cell. Class I here refers to classical class I molecules.
2481	antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent	P	The process in which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC class Ib protein complex following intracellular transport via a TAP (transporter associated with antigen processing) pathway. The peptide is typically a fragment of a larger exogenous protein which has been degraded within the cell and is dependent on TAP transport from the cytosol to ER for association with the MHC class Ib molecule. Class Ib here refers to non-classical class I molecules, such as those of the HLA-E gene family.
2482	antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-independent	P	The process in which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC class Ib protein complex following intracellular transport via a pathway not requiring TAP (transporter associated with antigen processing). The peptide is typically a fragment of a larger exogenous protein which has been degraded within the cell. Class Ib here refers to non-classical class I molecules, such as those of the HLA-E gene family.
2483	antigen processing and presentation of endogenous peptide antigen	P	The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC protein complex. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell.
2484	antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway	P	The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class I protein complex following intracellular transport via an ER pathway. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell and becomes associated with the MHC class I molecule in the ER. Class I here refers to classical class I molecules.
2485	antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent	P	The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class I protein complex following intracellular transport via a TAP-dependent ER pathway. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell and becomes associated with the MHC class I molecule in the ER following TAP-dependent transport from the cytosol. Class I here refers to classical class I molecules.
2486	antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent	P	The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class I protein complex following intracellular transport via a TAP-independent ER pathway. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell and becomes associated with the MHC class I molecule in the ER following transport from the cytosol via a TAP-independent pathway. Class I here refers to classical class I molecules.
2487	antigen processing and presentation of endogenous peptide antigen via MHC class I via endolysosomal pathway	P	The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class I protein complex. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell and becomes associated with the MHC class I molecule in an endolysosome. Class I here refers to classical class I molecules.
2488	antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway	P	The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class Ib protein complex following intracellular transport via an ER pathway. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell and becomes associated with the MHC class Ib molecule in the ER. Class Ib here refers to non-classical class I molecules, such as those of the HLA-E gene family.
2489	antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent	P	The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class Ib protein complex following intracellular transport via a TAP (transporter associated with antigen processing) pathway. The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell and is dependent on TAP transport from the cytosol to ER for association with the MHC class Ib molecule. Class Ib here refers to non-classical class I molecules, such as those of the HLA-E gene family.
2490	antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-independent	P	The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class Ib protein complex following intracellular transport via a pathway not requiring TAP (transporter associated with antigen processing). The peptide is typically a fragment of a larger endogenous protein which has been degraded within the cell. Class Ib here refers to non-classical class I molecules, such as those of the HLA-E gene family.
2491	antigen processing and presentation of endogenous peptide antigen via MHC class II	P	The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class II protein complex. The peptide antigen is typically, but not always, processed from a whole protein.
2492	peptide antigen assembly with MHC class Ib protein complex	P	The binding of a peptide antigen to the antigen binding groove of an MHC class Ib protein complex. Class Ib here refers to non-classical class I molecules, such as those of the HLA-E gene family.
2493	lipid antigen assembly with MHC class Ib protein complex	P	The binding of a lipid antigen to the antigen binding groove of an MHC class Ib protein complex. Class Ib here refers to non-classical class I molecules, such as those of the CD1 gene family.
2494	lipid antigen transport	P	The directed movement of a lipid antigen into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
2495	antigen processing and presentation of peptide antigen via MHC class II	P	The process in which an antigen-presenting cell expresses a peptide antigen on its cell surface in association with an MHC class II protein complex. The peptide antigen is typically, but not always, processed from a whole protein.
2496	proteolysis associated with antigen processing and presentation	P	The hydrolysis of a peptide bond or bonds within a protein contributing to antigen processing and presentation.
2497	proteasomal proteolysis associated with antigen processing and presentation	P	The hydrolysis of a peptide bond or bonds within a protein by the proteasome complex contributing to antigen processing and presentation.
2498	proteolysis within endoplasmic reticulum associated with antigen processing and presentation	P	The hydrolysis of a peptide bond or bonds within a protein by ER resident proteases contributing to antigen processing and presentation.
2499	proteolysis within endosome associated with antigen processing and presentation	P	The hydrolysis of a peptide bond or bonds within a protein by endosomal resident proteases contributing to antigen processing and presentation.
2500	proteolysis within lysosome associated with antigen processing and presentation	P	The hydrolysis of a peptide bond or bonds within a protein by lysosomal resident proteases contributing to antigen processing and presentation.
2501	peptide antigen assembly with MHC protein complex	P	The binding of a peptide to the antigen binding groove of an MHC protein complex.
2502	peptide antigen assembly with MHC class I protein complex	P	The binding of a peptide to the antigen binding groove of an MHC class I protein complex. Class I here refers to classical class I molecules.
2503	peptide antigen assembly with MHC class II protein complex	P	The binding of a peptide to the antigen binding groove of an MHC class II protein complex.
2504	antigen processing and presentation of peptide or polysaccharide antigen via MHC class II	P	The process in which an antigen-presenting cell expresses antigen (peptide or polysaccharide) on its cell surface in association with an MHC class II protein complex.
2505	antigen processing and presentation of polysaccharide antigen via MHC class II	P	The process in which an antigen-presenting cell expresses a polysaccharide antigen on its cell surface in association with an MHC class II protein complex.
2506	polysaccharide assembly with MHC class II protein complex	P	The binding of a polysaccharide to the antigen binding groove of an MHC class II protein complex.
2507	tolerance induction	P	A process that directly activates any of the steps required for tolerance, a physiologic state in which the immune system does not react destructively against the components of an organism that harbors it or against antigens that are introduced to it.
2508	central tolerance induction	P	Tolerance induction in the central lymphoid organs: the thymus and bone marrow.
2509	central tolerance induction to self antigen	P	Tolerance induction in the central lymphoid organs directed at self antigens.
2510	central B cell tolerance induction	P	Tolerance induction of B cells in the bone marrow.
2511	central B cell receptor editing	P	Receptor editing occurring in B cells in the bone marrow.
2512	central T cell tolerance induction	P	Tolerance induction of T cells in the thymus.
2513	tolerance induction to self antigen	P	Tolerance induction directed at self antigens.
2514	B cell tolerance induction	P	A process involving any mechanism for tolerance induction in B cells.
2515	B cell anergy	P	Any process contributing to anergy in B cells, a state of functional inactivation which is part of B cell tolerance induction.
2516	B cell deletion	P	The apoptotic death of B cells which is part of B cell tolerance induction.
2517	T cell tolerance induction	P	A process involving any mechanism for tolerance induction in T cells.
2518	lymphocyte chemotaxis across high endothelial venule	P	The movement of a lymphocyte to cross a high endothelial venule in response to an external stimulus.
2519	natural killer cell tolerance induction	P	Tolerance induction of natural killer cells.
2520	immune system development	P	The process whose specific outcome is the progression of an organismal system whose objective is to provide calibrated responses by an organism to a potential internal or invasive threat, over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process.
2521	leukocyte differentiation	P	The process in which a relatively unspecialized hemopoietic precursor cell acquires the specialized features of a leukocyte. A leukocyte is an achromatic cell of the myeloid or lymphoid lineages capable of ameboid movement, found in blood or other tissue.
2522	leukocyte migration involved in immune response	P	The movement of a leukocyte within or between different tissues and organs of the body as part of an immune response.
2523	leukocyte migration involved in inflammatory response	P	The movement of a leukocyte within or between different tissues and organs of the body contributing to an inflammatory response.
2524	hypersensitivity	P	An inflammatory response to an exogenous environmental antigen or an endogenous antigen initiated by the adaptive immune system.
2525	acute inflammatory response to non-antigenic stimulus	P	An acute inflammatory response to non-antigenic stimuli such as heat or physical trauma.
2526	acute inflammatory response	P	Inflammation which comprises a rapid, short-lived, relatively uniform response to acute injury or antigenic challenge and is characterized by accumulations of fluid, plasma proteins, and granulocytic leukocytes. An acute inflammatory response occurs within a matter of minutes or hours, and either resolves within a few days or becomes a chronic inflammatory response.
2527	vasodilation involved in acute inflammatory response	P	An increase in the internal diameter of blood vessels, especially arterioles or capillaries, usually resulting in a decrease in blood pressure contributing to an acute inflammatory response.
2528	regulation of vascular permeability involved in acute inflammatory response	P	Any process that modulates the extent to which blood vessels can be pervaded by fluid contributing to an acute inflammatory response.
2529	regulation of plasma kallikrein-kinin cascade	P	Any process that modulates the frequency, rate, or extent of the plasma kallikrein-kinin cascade.
2530	regulation of systemic arterial blood pressure involved in acute-phase response	P	Any process that modulates the force with which blood travels through the circulatory system that contributes to the acute phase response. The acute phase response occurs during the early phases of an infection and is marked by changes in the production of plasma proteins such as C-reactive protein.
2531	regulation of heart contraction involved in acute-phase response	P	Any process that modulates the frequency, rate or extent of heart contraction that contributes to the acute phase response. The acute phase response occurs during the early phases of an infection and is marked by changes in the production of plasma proteins such as C-reactive protein.
2532	production of molecular mediator involved in inflammatory response	P	The synthesis or release of any molecular mediator of the inflammatory response following an inflammatory stimulus, resulting in an increase in its intracellular or extracellular levels.
2533	lysosomal enzyme secretion involved in inflammatory response	P	The regulated release of lysosomal enzymes by a cell as part of an inflammatory response.
2534	cytokine production involved in inflammatory response	P	The synthesis or release of a cytokine following a inflammatory stimulus as part of an inflammatory response, resulting in an increase in its intracellular or extracellular levels.
2535	platelet activating factor secretion involved in inflammatory response	P	The regulated release of platelet activating factor by a cell as part of an inflammatory response.
2536	respiratory burst involved in inflammatory response	P	A phase of elevated metabolic activity, during which oxygen consumption increases following a stimulus as part of an inflammatory response; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals, resulting in an increase in their intracellular or extracellular levels.
2537	nitric oxide production involved in inflammatory response	P	The synthesis or release of nitric oxide following a stimulus as part of an inflammatory response, resulting in an increase in its intracellular or extracellular levels.
2538	arachidonic acid metabolite production involved in inflammatory response	P	The synthesis or release of products of arachidonic acid metabolism following a stimulus as part of an inflammatory response, resulting in an increase in their intracellular or extracellular levels.
2539	prostaglandin production involved in inflammatory response	P	The synthesis or release of any prostaglandin following a stimulus as part of an inflammatory response, resulting in an increase in its intracellular or extracellular levels.
2540	leukotriene production involved in inflammatory response	P	The synthesis or release of any leukotriene following a stimulus as part of an inflammatory response, resulting in an increase in its intracellular or extracellular levels.
2541	activation of plasma proteins involved in acute inflammatory response	P	Any process activating plasma proteins by proteolysis as part of an acute inflammatory response.
2542	Factor XII activation	P	Any process that activates Factor XII (Hageman factor). Factor XII is a protein synthesized by the liver that circulates in an inactive form until it encounters collagen or basement membrane or activated platelets (as occurs at the site of endothelial injury). Factor XII then undergoes a conformational change (becoming factor XIIa), exposing an active serine center that can subsequently cleave protein substrates and activate a variety of mediator systems. Factor XII is a participant in the clotting cascade as well as the kinin cascade.
2543	activation of blood coagulation via clotting cascade	P	Any process that initiates the clotting cascade of blood coagulation, a cascade of plasma enzymes that is triggered following damage to blood vessels, leading to formation of a clot.
2544	chronic inflammatory response	P	Inflammation of prolonged duration (weeks or months) in which active inflammation, tissue destruction, and attempts at repair are proceeding simultaneously. Although it may follow acute inflammation, chronic inflammation frequently begins insidiously, as a low-grade, smoldering, often asymptomatic response.
2545	chronic inflammatory response to non-antigenic stimulus	P	A chronic inflammatory response to a non-antigenic stimulus such as heat or physical trauma.
2546	negative regulation of tissue kallikrein-kinin cascade	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of the tissue kallikrein-kinin cascade.
2547	positive regulation of tissue kallikrein-kinin cascade	P	Any process that activates or increases the frequency, rate, or extent of the tissue kallikrein-kinin cascade.
2548	monocyte chemotaxis	P	The movement of a monocyte in response to an external stimulus.
2549	negative regulation of plasma kallikrein-kinin cascade	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of the plasma kallikrein-kinin cascade.
2550	positive regulation of plasma kallikrein-kinin cascade	P	Any process that activates or increases the frequency, rate, or extent of the plasma kallikrein-kinin cascade.
2551	mast cell chemotaxis	P	The movement of a mast cell in response to an external stimulus.
2552	serotonin secretion by mast cell	P	The regulated release of serotonin by a mast cell or group of mast cells.
2553	histamine secretion by mast cell	P	The regulated release of histamine by a mast cell or group of mast cells.
2554	serotonin secretion by platelet	P	The regulated release of serotonin by a platelet or group of platelets.
2555	histamine secretion by platelet	P	The regulated release of histamine by a platelet or group of platelets.
2556	serotonin secretion by basophil	P	The regulated release of serotonin by a basophil or group of basophils.
2557	histamine secretion by basophil	P	The regulated release of histamine by a basophil or group of basophils.
2558	type I hypersensitivity mediated by mast cells	P	An inflammatory response driven by antigen recognition by antibodies bound to Fc receptors on mast cells, occurring within minutes after exposure of a sensitized individual to the antigen, and leading to the release of a variety of inflammatory mediators such as histamines.
2559	type I hypersensitivity mediated by basophils	P	An inflammatory response driven by antigen recognition by antibodies bound to Fc receptors basophils, occurring within minutes after exposure of a sensitized individual to the antigen, and leading to the release of a variety of inflammatory mediators such as histamines.
2560	basophil mediated immunity	P	Any process involved in the carrying out of an immune response by a basophil.
2561	basophil degranulation	P	The regulated exocytosis of secretory granules containing preformed mediators such as histamine, serotonin, and neutral proteases by a basophil.
2562	somatic diversification of immune receptors via germline recombination within a single locus	P	The process in which immune receptor genes are diversified through recombination of the germline genetic elements within a single genetic locus.
2563	somatic diversification of immune receptors via alternate splicing	P	The process in which immune receptor genes are diversified through alternate splicing.
2564	alternate splicing of immunoglobulin genes	P	The generation of alternate transcripts of immunoglobulin genes through alternate splicing of exons.
2565	somatic diversification of immune receptors via gene conversion	P	The process in which immune receptor genes are diversified through gene conversion.
2566	somatic diversification of immune receptors via somatic mutation	P	The process in which immune receptor genes are diversified through somatic mutation.
2567	somatic diversification of FREP-based immune receptors	P	The process that results in the generation of sequence diversity of the FREP-based immune receptors of snails.
2568	somatic diversification of T cell receptor genes	P	The somatic process that results in the generation of sequence diversity of T cell receptor genes.
2569	somatic diversification of immune receptors by N region addition	P	The addition of variable numbers of random nucleotides by terminal deoxytransferase in the N regions of heavy chain immunoglobulin and T cell receptor genes. N regions are found at the V-D, D-D, V-J, and D-J recombinational junctions, depending on the immune receptor gene.
2570	somatic diversification of immunoglobulin genes by N region addition	P	The addition of variable numbers of random nucleotides by terminal deoxytransferase in the N regions of heavy chain immunoglobulin genes. N regions are found at the V-D and D-J recombinational junctions.
2571	somatic diversification of T cell receptor genes by N region addition	P	The addition of variable numbers of random nucleotides by terminal deoxytransferase in the N regions of T cell receptor genes. N regions are found at the V-D, D-D, V-J, and D-J recombinational junctions, depending on the T cell receptor gene.
2572	pro-T cell differentiation	P	The process in which a precursor cell type acquires the specialized features of a pro-T cell. Pro-T cells are the earliest stage of the T cell lineage but are not fully committed.
2573	myeloid leukocyte differentiation	P	The process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of any cell of the myeloid leukocyte lineage.
2574	thrombocyte differentiation	P	The process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of a thrombocyte, a nucleated cell found in all vertebrates but mammals involved in hemostasis.
2575	basophil chemotaxis	P	The movement of a basophil in response to an external stimulus.
2576	platelet degranulation	P	The regulated exocytosis of secretory granules containing preformed mediators such as histamine and serotonin by a platelet.
2577	regulation of antigen processing and presentation	P	Any process that modulates the frequency, rate, or extent of antigen processing and presentation.
2578	negative regulation of antigen processing and presentation	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation.
2579	positive regulation of antigen processing and presentation	P	Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation.
2580	regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II	P	Any process that modulates the frequency, rate, or extent of antigen processing and presentation of antigen (peptide or polysaccharide) via MHC class II.
2581	negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of antigen (peptide or polysaccharide) via MHC class II.
2582	positive regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II	P	Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation of antigen (peptide or polysaccharide) via MHC class II.
2583	regulation of antigen processing and presentation of peptide antigen	P	Any process that modulates the frequency, rate, or extent of antigen processing and presentation of peptide antigen.
2584	negative regulation of antigen processing and presentation of peptide antigen	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of peptide antigen.
2585	positive regulation of antigen processing and presentation of peptide antigen	P	Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation of peptide antigen.
2586	regulation of antigen processing and presentation of peptide antigen via MHC class II	P	Any process that modulates the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class II.
2587	negative regulation of antigen processing and presentation of peptide antigen via MHC class II	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class II.
2588	positive regulation of antigen processing and presentation of peptide antigen via MHC class II	P	Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class II.
2589	regulation of antigen processing and presentation of peptide antigen via MHC class I	P	Any process that modulates the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class I.
2590	negative regulation of antigen processing and presentation of peptide antigen via MHC class I	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class I.
2591	positive regulation of antigen processing and presentation of peptide antigen via MHC class I	P	Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class I.
2592	regulation of antigen processing and presentation via MHC class Ib	P	Any process that modulates the frequency, rate, or extent of antigen processing and presentation of antigen via MHC class Ib.
2593	negative regulation of antigen processing and presentation via MHC class Ib	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of antigen via MHC class Ib.
2594	positive regulation of antigen processing and presentation via MHC class Ib	P	Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation of antigen via MHC class Ib.
2595	regulation of antigen processing and presentation of peptide antigen via MHC class Ib	P	Any process that modulates the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class Ib.
2596	negative regulation of antigen processing and presentation of peptide antigen via MHC class Ib	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class Ib.
2597	positive regulation of antigen processing and presentation of peptide antigen via MHC class Ib	P	Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation of peptide antigen via MHC class Ib.
2598	regulation of antigen processing and presentation of lipid antigen via MHC class Ib	P	Any process that modulates the frequency, rate, or extent of antigen processing and presentation of lipid antigen via MHC class Ib.
2599	negative regulation of antigen processing and presentation of lipid antigen via MHC class Ib	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of lipid antigen via MHC class Ib.
2600	positive regulation of antigen processing and presentation of lipid antigen via MHC class Ib	P	Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation of lipid antigen via MHC class Ib.
2601	regulation of antigen processing and presentation of polysaccharide antigen via MHC class II	P	Any process that modulates the frequency, rate, or extent of antigen processing and presentation of polysaccharide antigen via MHC class II.
2602	negative regulation of antigen processing and presentation of polysaccharide antigen via MHC class II	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of antigen processing and presentation of polysaccharide antigen via MHC class II.
2603	positive regulation of antigen processing and presentation of polysaccharide antigen via MHC class II	P	Any process that activates or increases the frequency, rate, or extent of antigen processing and presentation of polysaccharide antigen via MHC class II.
2604	regulation of dendritic cell antigen processing and presentation	P	Any process that modulates the frequency, rate, or extent of dendritic cell antigen processing and presentation.
2605	negative regulation of dendritic cell antigen processing and presentation	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of dendritic cell antigen processing and presentation.
2606	positive regulation of dendritic cell antigen processing and presentation	P	Any process that activates or increases the frequency, rate, or extent of dendritic cell antigen processing and presentation.
2607	regulation of myeloid dendritic cell antigen processing and presentation	P	Any process that modulates the frequency, rate, or extent of myeloid dendritic cell antigen processing and presentation.
2608	negative regulation of myeloid dendritic cell antigen processing and presentation	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of myeloid dendritic cell antigen processing and presentation.
2609	positive regulation of myeloid dendritic cell antigen processing and presentation	P	Any process that activates or increases the frequency, rate, or extent of myeloid dendritic cell antigen processing and presentation.
2610	regulation of plasmacytoid dendritic cell antigen processing and presentation	P	Any process that modulates the frequency, rate, or extent of plasmacytoid dendritic cell antigen processing and presentation.
2611	negative regulation of plasmacytoid dendritic cell antigen processing and presentation	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of plasmacytoid dendritic cell antigen processing and presentation.
2612	positive regulation of plasmacytoid dendritic cell antigen processing and presentation	P	Any process that activates or increases the frequency, rate, or extent of plasmacytoid dendritic cell antigen processing and presentation.
2613	regulation of monocyte antigen processing and presentation	P	Any process that modulates the frequency, rate, or extent of monocyte antigen processing and presentation.
2614	negative regulation of monocyte antigen processing and presentation	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of monocyte antigen processing and presentation.
2615	positive regulation of monocyte antigen processing and presentation	P	Any process that activates or increases the frequency, rate, or extent of monocyte antigen processing and presentation.
2616	regulation of macrophage antigen processing and presentation	P	Any process that modulates the frequency, rate, or extent of macrophage antigen processing and presentation.
2617	negative regulation of macrophage antigen processing and presentation	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of macrophage antigen processing and presentation.
2618	positive regulation of macrophage antigen processing and presentation	P	Any process that activates or increases the frequency, rate, or extent of macrophage antigen processing and presentation.
2619	regulation of non-professional antigen presenting cell antigen processing and presentation	P	Any process that modulates the frequency, rate, or extent of non-professional antigen presenting cell antigen processing and presentation.
2620	negative regulation of non-professional antigen presenting cell antigen processing and presentation	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of non-professional antigen presenting cell antigen processing and presentation.
2621	positive regulation of non-professional antigen presenting cell antigen processing and presentation	P	Any process that activates or increases the frequency, rate, or extent of non-professional antigen presenting cell antigen processing and presentation.
2622	regulation of B cell antigen processing and presentation	P	Any process that modulates the frequency, rate, or extent of B cell antigen processing and presentation.
2623	negative regulation of B cell antigen processing and presentation	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of B cell antigen processing and presentation.
2624	positive regulation of B cell antigen processing and presentation	P	Any process that activates or increases the frequency, rate, or extent of B cell antigen processing and presentation.
2625	regulation of T cell antigen processing and presentation	P	Any process that modulates the frequency, rate, or extent of T cell antigen processing and presentation.
2626	negative regulation of T cell antigen processing and presentation	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell antigen processing and presentation.
2627	positive regulation of T cell antigen processing and presentation	P	Any process that activates or increases the frequency, rate, or extent of T cell antigen processing and presentation.
2628	regulation of proteolysis associated with antigen processing and presentation	P	Any process that modulates the frequency, rate, or extent of proteolysis associated with antigen processing and presentation.
2629	negative regulation of proteolysis associated with antigen processing and presentation	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of proteolysis associated with antigen processing and presentation.
2630	positive regulation of proteolysis associated with antigen processing and presentation	P	Any process that activates or increases the frequency, rate, or extent of proteolysis associated with antigen processing and presentation.
2631	regulation of granuloma formation	P	Any process that modulates the frequency, rate, or extent of granuloma formation.
2632	negative regulation of granuloma formation	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of granuloma formation.
2633	positive regulation of granuloma formation	P	Any process that activates or increases the frequency, rate, or extent of granuloma formation.
2634	regulation of germinal center formation	P	Any process that modulates the frequency, rate, or extent of germinal center formation.
2635	negative regulation of germinal center formation	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of germinal center formation.
2636	positive regulation of germinal center formation	P	Any process that activates or increases the frequency, rate, or extent of germinal center formation.
2637	regulation of immunoglobulin production	P	Any process that modulates the frequency, rate, or extent of immunoglobulin production.
2638	negative regulation of immunoglobulin production	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of immunoglobulin production.
2639	positive regulation of immunoglobulin production	P	Any process that activates or increases the frequency, rate, or extent of immunoglobulin production.
2640	regulation of immunoglobulin biosynthetic process	P	Any process that modulates the frequency, rate, or extent of immunoglobulin biosynthesis.
2641	negative regulation of immunoglobulin biosynthetic process	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of immunoglobulin biosynthesis.
2642	positive regulation of immunoglobulin biosynthetic process	P	Any process that activates or increases the frequency, rate, or extent of immunoglobulin biosynthesis.
2643	regulation of tolerance induction	P	Any process that modulates the frequency, rate, or extent of tolerance induction.
2644	negative regulation of tolerance induction	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of tolerance induction.
2645	positive regulation of tolerance induction	P	Any process that activates or increases the frequency, rate, or extent of tolerance induction.
2646	regulation of central tolerance induction	P	Any process that modulates the frequency, rate, or extent of central tolerance induction.
2647	negative regulation of central tolerance induction	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of central tolerance induction.
2648	positive regulation of central tolerance induction	P	Any process that activates or increases the frequency, rate, or extent of central tolerance induction.
2649	regulation of tolerance induction to self antigen	P	Any process that modulates the frequency, rate, or extent of tolerance induction to self antigen.
2650	negative regulation of tolerance induction to self antigen	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of tolerance induction to self antigen.
2651	positive regulation of tolerance induction to self antigen	P	Any process that activates or increases the frequency, rate, or extent of tolerance induction to self antigen.
2652	regulation of tolerance induction dependent upon immune response	P	Any process that modulates the frequency, rate, or extent of tolerance induction dependent upon immune response.
2653	negative regulation of tolerance induction dependent upon immune response	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of tolerance induction dependent upon immune response.
2654	positive regulation of tolerance induction dependent upon immune response	P	Any process that activates or increases the frequency, rate, or extent of tolerance induction dependent upon immune response.
2655	regulation of tolerance induction to nonself antigen	P	Any process that modulates the frequency, rate, or extent of tolerance induction to nonself antigen.
2656	negative regulation of tolerance induction to nonself antigen	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of tolerance induction to nonself antigen.
2657	positive regulation of tolerance induction to nonself antigen	P	Any process that activates or increases the frequency, rate, or extent of tolerance induction to nonself antigen.
2658	regulation of peripheral tolerance induction	P	Any process that modulates the frequency, rate, or extent of peripheral tolerance induction.
2659	negative regulation of peripheral tolerance induction	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of peripheral tolerance induction.
2660	positive regulation of peripheral tolerance induction	P	Any process that activates or increases the frequency, rate, or extent of peripheral tolerance induction.
2661	regulation of B cell tolerance induction	P	Any process that modulates the frequency, rate, or extent of B cell tolerance induction.
2662	negative regulation of B cell tolerance induction	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of B cell tolerance induction.
2663	positive regulation of B cell tolerance induction	P	Any process that activates or increases the frequency, rate, or extent of B cell tolerance induction.
2664	regulation of T cell tolerance induction	P	Any process that modulates the frequency, rate, or extent of T cell tolerance induction.
2665	negative regulation of T cell tolerance induction	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell tolerance induction.
2666	positive regulation of T cell tolerance induction	P	Any process that activates or increases the frequency, rate, or extent of T cell tolerance induction.
2667	regulation of T cell anergy	P	Any process that modulates the frequency, rate, or extent of T cell anergy.
2668	negative regulation of T cell anergy	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell anergy.
2669	positive regulation of T cell anergy	P	Any process that activates or increases the frequency, rate, or extent of T cell anergy.
2670	regulation of B cell anergy	P	Any process that modulates the frequency, rate, or extent of B cell anergy.
2671	negative regulation of B cell anergy	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of B cell anergy.
2672	positive regulation of B cell anergy	P	Any process that activates or increases the frequency, rate, or extent of B cell anergy.
2673	regulation of acute inflammatory response	P	Any process that modulates the frequency, rate, or extent of an acute inflammatory response.
2674	negative regulation of acute inflammatory response	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of an acute inflammatory response.
2675	positive regulation of acute inflammatory response	P	Any process that activates or increases the frequency, rate, or extent of an acute inflammatory response.
2676	regulation of chronic inflammatory response	P	Any process that modulates the frequency, rate, or extent of a chronic inflammatory response.
2677	negative regulation of chronic inflammatory response	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of a chronic inflammatory response.
2678	positive regulation of chronic inflammatory response	P	Any process that activates or increases the frequency, rate, or extent of a chronic inflammatory response.
2679	respiratory burst involved in defense response	P	A phase of elevated metabolic activity, during which oxygen consumption increases made as part of a defense response; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals.
2680	pro-T cell lineage commitment	P	The process in which a lymphoid progenitor cell becomes committed to becoming a pro-T cell.
2681	somatic recombination of T cell receptor gene segments	P	The process in which T cell receptor genes are formed through recombination of the germline genetic elements, also known as T cell receptor gene segments.
2682	regulation of immune system process	P	Any process that modulates the frequency, rate, or extent of an immune system process.
2683	negative regulation of immune system process	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of an immune system process.
2684	positive regulation of immune system process	P	Any process that activates or increases the frequency, rate, or extent of an immune system process.
2685	regulation of leukocyte migration	P	Any process that modulates the frequency, rate, or extent of leukocyte migration.
2686	negative regulation of leukocyte migration	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of leukocyte migration.
2687	positive regulation of leukocyte migration	P	Any process that activates or increases the frequency, rate, or extent of leukocyte migration.
2688	regulation of leukocyte chemotaxis	P	Any process that modulates the frequency, rate, or extent of leukocyte chemotaxis.
2689	negative regulation of leukocyte chemotaxis	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of leukocyte chemotaxis.
2690	positive regulation of leukocyte chemotaxis	P	Any process that activates or increases the frequency, rate, or extent of leukocyte chemotaxis.
2691	regulation of cellular extravasation	P	Any process that modulates the frequency, rate, or extent of cellular extravasation.
2692	negative regulation of cellular extravasation	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of cellular extravasation.
2693	positive regulation of cellular extravasation	P	Any process that activates or increases the frequency, rate, or extent of cellular extravasation.
2694	regulation of leukocyte activation	P	Any process that modulates the frequency, rate, or extent of leukocyte activation.
2695	negative regulation of leukocyte activation	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of leukocyte activation.
2696	positive regulation of leukocyte activation	P	Any process that activates or increases the frequency, rate, or extent of leukocyte activation.
2697	regulation of immune effector process	P	Any process that modulates the frequency, rate, or extent of an immune effector process.
2698	negative regulation of immune effector process	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of an immune effector process.
2699	positive regulation of immune effector process	P	Any process that activates or increases the frequency, rate, or extent of an immune effector process.
2700	regulation of production of molecular mediator of immune response	P	Any process that modulates the frequency, rate, or extent of the production of molecular mediator of immune response.
2701	negative regulation of production of molecular mediator of immune response	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of the production of molecular mediator of immune response.
2702	positive regulation of production of molecular mediator of immune response	P	Any process that activates or increases the frequency, rate, or extent of the production of molecular mediator of immune response.
2703	regulation of leukocyte mediated immunity	P	Any process that modulates the frequency, rate, or extent of leukocyte mediated immunity.
2704	negative regulation of leukocyte mediated immunity	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of leukocyte mediated immunity.
2705	positive regulation of leukocyte mediated immunity	P	Any process that activates or increases the frequency, rate, or extent of leukocyte mediated immunity.
2706	regulation of lymphocyte mediated immunity	P	Any process that modulates the frequency, rate, or extent of lymphocyte mediated immunity.
2707	negative regulation of lymphocyte mediated immunity	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of lymphocyte mediated immunity.
2708	positive regulation of lymphocyte mediated immunity	P	Any process that activates or increases the frequency, rate, or extent of lymphocyte mediated immunity.
2709	regulation of T cell mediated immunity	P	Any process that modulates the frequency, rate, or extent of T cell mediated immunity.
2710	negative regulation of T cell mediated immunity	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell mediated immunity.
2711	positive regulation of T cell mediated immunity	P	Any process that activates or increases the frequency, rate, or extent of T cell mediated immunity.
2712	regulation of B cell mediated immunity	P	Any process that modulates the frequency, rate, or extent of B cell mediated immunity.
2713	negative regulation of B cell mediated immunity	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of B cell mediated immunity.
2714	positive regulation of B cell mediated immunity	P	Any process that activates or increases the frequency, rate, or extent of B cell mediated immunity.
2715	regulation of natural killer cell mediated immunity	P	Any process that modulates the frequency, rate, or extent of natural killer cell mediated immunity.
2716	negative regulation of natural killer cell mediated immunity	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of natural killer cell mediated immunity.
2717	positive regulation of natural killer cell mediated immunity	P	Any process that activates or increases the frequency, rate, or extent of natural killer cell mediated immunity.
2718	regulation of cytokine production involved in immune response	P	Any process that modulates the frequency, rate, or extent of cytokine production that contributes to an immune response.
2719	negative regulation of cytokine production involved in immune response	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of cytokine production contributing to an immune response.
2720	positive regulation of cytokine production involved in immune response	P	Any process that activates or increases the frequency, rate, or extent of cytokine production that contributes to an immune response.
2721	regulation of B cell cytokine production	P	Any process that modulates the frequency, rate, or extent of B cell cytokine production.
2722	negative regulation of B cell cytokine production	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of B cell cytokine production.
2723	positive regulation of B cell cytokine production	P	Any process that activates or increases the frequency, rate, or extent of B cell cytokine production.
2724	regulation of T cell cytokine production	P	Any process that modulates the frequency, rate, or extent of T cell cytokine production.
2725	negative regulation of T cell cytokine production	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell cytokine production.
2726	positive regulation of T cell cytokine production	P	Any process that activates or increases the frequency, rate, or extent of T cell cytokine production.
2727	regulation of natural killer cell cytokine production	P	Any process that modulates the frequency, rate, or extent of natural killer cell cytokine production.
2728	negative regulation of natural killer cell cytokine production	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of natural killer cell cytokine production.
2729	positive regulation of natural killer cell cytokine production	P	Any process that activates or increases the frequency, rate, or extent of natural killer cell cytokine production.
2730	regulation of dendritic cell cytokine production	P	Any process that modulates the frequency, rate, or extent of dendritic cell cytokine production.
2731	negative regulation of dendritic cell cytokine production	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of dendritic cell cytokine production.
2732	positive regulation of dendritic cell cytokine production	P	Any process that activates or increases the frequency, rate, or extent of dendritic cell cytokine production.
2733	regulation of myeloid dendritic cell cytokine production	P	Any process that modulates the frequency, rate, or extent of myeloid dendritic cell cytokine production.
2734	negative regulation of myeloid dendritic cell cytokine production	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of myeloid dendritic cell cytokine production.
2735	positive regulation of myeloid dendritic cell cytokine production	P	Any process that activates or increases the frequency, rate, or extent of myeloid dendritic cell cytokine production.
2736	regulation of plasmacytoid dendritic cell cytokine production	P	Any process that modulates the frequency, rate, or extent of plasmacytoid dendritic cell cytokine production.
2737	negative regulation of plasmacytoid dendritic cell cytokine production	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of plasmacytoid dendritic cell cytokine production.
2738	positive regulation of plasmacytoid dendritic cell cytokine production	P	Any process that activates or increases the frequency, rate, or extent of plasmacytoid dendritic cell cytokine production.
2739	regulation of cytokine secretion involved in immune response	P	Any process that modulates the frequency, rate, or extent of cytokine secretion contributing to an immune response.
2740	negative regulation of cytokine secretion involved in immune response	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of cytokine secretion contributing to an immune response.
2741	positive regulation of cytokine secretion involved in immune response	P	Any process that activates or increases the frequency, rate, or extent of cytokine secretion contributing to an immune response.
2742	regulation of cytokine biosynthetic process involved in immune response	P	Any process that modulates the frequency, rate, or extent of cytokine biosynthesis that contributes to an immune response.
2743	negative regulation of cytokine biosynthetic process involved in immune response	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of cytokine biosynthesis contributing to an immune response.
2744	positive regulation of cytokine biosynthetic process involved in immune response	P	Any process that activates or increases the frequency, rate, or extent of cytokine biosynthesis contributing to an immune response.
2745	antigen processing and presentation initiated by receptor mediated uptake of antigen	P	Antigen processing and presentation which is initiated by uptake of antigen bound to a cell surface receptor.
2746	antigen processing and presentation following pinocytosis	P	Antigen processing and presentation which is initiated by uptake of antigen via pinocytosis.
2747	antigen processing and presentation following phagocytosis	P	Antigen processing and presentation which is initiated by uptake of antigen via phagocytosis.
2748	antigen processing and presentation initiated by pattern recognition receptor mediated uptake of antigen	P	Antigen processing and presentation which is initiated by uptake of antigen bound to a cell surface pattern recognition receptor (PRR).
2749	antigen processing and presentation initiated by toll-like receptor mediated phagocytosis of antigen	P	Antigen processing and presentation which is initiated by phagocytosis of antigen bound directly or indirectly to a cell surface toll-like receptor (TLR).
2750	antigen processing and presentation following macropinocytosis	P	Antigen processing and presentation which is initiated by uptake of antigen via macropinocytosis.
2751	antigen processing and presentation following receptor mediated endocytosis	P	Antigen processing and presentation which is initiated by uptake of antigen receptor-mediated endocytosis.
2752	cell surface pattern recognition receptor signaling pathway	P	Any series of molecular signals generated as a consequence of a cell surface pattern recognition receptor (PRR) binding to one of its physiological ligands. PRRs bind pathogen-associated molecular pattern (PAMPs), structures conserved among microbial species, or damage-associated molecular pattern (DAMPs), endogenous molecules released from damaged cells.
2753	cytoplasmic pattern recognition receptor signaling pathway	P	Any series of molecular signals generated as a consequence of a cytoplasmic pattern recognition receptor (PRR) binding to one of its physiological ligands. PRRs bind pathogen-associated molecular pattern (PAMPs), structures conserved among microbial species, or damage-associated molecular pattern (DAMPs), endogenous molecules released from damaged cells.
2754	intracellular vesicle pattern recognition receptor signaling pathway	P	Any series of molecular signals generated as a consequence of an intracellular vesicle pattern recognition receptor (PRR) binding to one of its physiological ligands. PRRs bind pathogen-associated molecular pattern (PAMPs), structures conserved among microbial species, or damage-associated molecular pattern (DAMPs), endogenous molecules released from damaged cells.
2755	MyD88-dependent toll-like receptor signaling pathway	P	Any series of molecular signals generated as a consequence of binding to a toll-like receptor where the MyD88 adaptor molecule mediates transduction of the signal. Toll-like receptors directly bind pattern motifs from a variety of microbial sources to initiate innate immune response.
2756	MyD88-independent toll-like receptor signaling pathway	P	Any series of molecular signals generated as a consequence of binding to a toll-like receptor not relying on the MyD88 adaptor molecule. Toll-like receptors directly bind pattern motifs from a variety of microbial sources to initiate innate immune response.
2757	immune response-activating signal transduction	P	The cascade of processes by which a signal interacts with a receptor, causing a change in the level or activity of a second messenger or other downstream target, and ultimately leading to activation or perpetuation of an immune response.
2758	innate immune response-activating signal transduction	P	The cascade of processes by which a signal interacts with a receptor, causing a change in the level or activity of a second messenger or other downstream target, and ultimately leading to activation or perpetuation of an innate immune response.
2759	regulation of antimicrobial humoral response	P	Any process that modulates the frequency, rate, or extent of an antimicrobial humoral response.
2760	positive regulation of antimicrobial humoral response	P	Any process that activates or increases the frequency, rate, or extent of an antimicrobial humoral response.
2761	regulation of myeloid leukocyte differentiation	P	Any process that modulates the frequency, rate, or extent of myeloid leukocyte differentiation.
2762	negative regulation of myeloid leukocyte differentiation	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of myeloid leukocyte differentiation.
2763	positive regulation of myeloid leukocyte differentiation	P	Any process that activates or increases the frequency, rate, or extent of myeloid leukocyte differentiation.
2764	immune response-regulating signaling pathway	P	The cascade of processes by which a signal interacts with a receptor, causing a change in the level or activity of a second messenger or other downstream target, and ultimately leading to the activation, perpetuation, or inhibition of an immune response.
2765	immune response-inhibiting signal transduction	P	The cascade of processes by which a signal interacts with a receptor, causing a change in the level or activity of a second messenger or other downstream target, and ultimately leading to inhibition of an immune response.
2766	innate immune response-inhibiting signal transduction	P	The cascade of processes by which a signal interacts with a receptor, causing a change in the level or activity of a second messenger or other downstream target, and ultimately leading to inhibition of an innate immune response.
2767	immune response-inhibiting cell surface receptor signaling pathway	P	A series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell capable of inhibiting an immune response.
2768	immune response-regulating cell surface receptor signaling pathway	P	A series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell capable of activating, perpetuating, or inhibiting an immune response.
2769	natural killer cell inhibitory signaling pathway	P	A series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of a natural killer cell capable of inhibiting an immune effector process contributing to an immune response.
2770	T cell inhibitory signaling pathway	P	A series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of a T cell capable of inhibiting an immune effector process contributing to an immune response.
2771	inhibitory killer cell immunoglobulin-like receptor signaling pathway	P	A series of molecular signals initiated by the binding of an extracellular ligand to a inhibitory killer cell immunoglobulin-like receptor capable of inhibiting an immune effector process contributing to an immune response.
2772	inhibitory C-type lectin receptor signaling pathway	P	A series of molecular signals initiated by the binding of an extracellular ligand to an inhibitory C-type lectin receptor capable of inhibiting an immune effector process contributing to an immune response.
2773	B cell inhibitory signaling pathway	P	A series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of a B cell capable of inhibiting an immune effector process contributing to an immune response.
2774	Fc receptor mediated inhibitory signaling pathway	P	A series of molecular signals generated as a consequence of the binding of the Fc portion of an immunoglobulin by an Fc receptor capable of inhibiting an immune effector process contributing to an immune response. The Fc portion of an immunoglobulin is its C-terminal constant region.
2775	antimicrobial peptide production	P	The synthesis or release of an antimicrobial peptide during an immune response, resulting in an increase in intracellular or extracellular levels. Such peptides may have protective properties against bacteria, fungi, viruses, or protozoa.
2776	antimicrobial peptide secretion	P	The regulated release of an antimicrobial peptide from a cell or a tissue. Such peptides may have protective properties against bacteria, fungi, viruses, or protozoa.
2777	antimicrobial peptide biosynthetic process	P	The chemical reactions and pathways resulting in the formation of an antimicrobial peptide. Such peptides may have protective properties against bacteria, fungi, viruses, or protozoa.
2778	antibacterial peptide production	P	The synthesis or release of an antibacterial peptide during an immune response, resulting in an increase in intracellular or extracellular levels.
2779	antibacterial peptide secretion	P	The regulated release of an antibacterial peptide from a cell or a tissue.
2780	antibacterial peptide biosynthetic process	P	The chemical reactions and pathways resulting in the formation of an antibacterial peptide.
2781	antifungal peptide production	P	The synthesis or release of an antifungal peptide during an immune response, resulting in an increase in intracellular or extracellular levels.
2782	antifungal peptide secretion	P	The regulated release of an antifungal peptide from a cell or a tissue.
2783	antifungal peptide biosynthetic process	P	The chemical reactions and pathways resulting in the formation of an antifungal peptide.
2784	regulation of antimicrobial peptide production	P	Any process that modulates the frequency, rate, or extent of antimicrobial peptide production.
2785	negative regulation of antimicrobial peptide production	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of antimicrobial peptide production.
2786	regulation of antibacterial peptide production	P	Any process that modulates the frequency, rate, or extent of antibacterial peptide production.
2787	negative regulation of antibacterial peptide production	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of antibacterial peptide production.
2788	regulation of antifungal peptide production	P	Any process that modulates the frequency, rate, or extent of antifungal peptide production.
2789	negative regulation of antifungal peptide production	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of antifungal peptide production.
2790	peptide secretion	P	The controlled release of a peptide from a cell or a tissue.
2791	regulation of peptide secretion	P	Any process that modulates the frequency, rate, or extent of peptide secretion.
2792	negative regulation of peptide secretion	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of peptide secretion.
2793	positive regulation of peptide secretion	P	Any process that activates or increases the frequency, rate, or extent of peptide secretion.
2794	regulation of antimicrobial peptide secretion	P	Any process that modulates the frequency, rate, or extent of antimicrobial peptide secretion.
2795	negative regulation of antimicrobial peptide secretion	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of antimicrobial peptide secretion.
2796	positive regulation of antimicrobial peptide secretion	P	Any process that activates or increases the frequency, rate, or extent of antimicrobial peptide secretion.
2797	regulation of antibacterial peptide secretion	P	Any process that modulates the frequency, rate, or extent of antibacterial peptide secretion.
2798	negative regulation of antibacterial peptide secretion	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of antibacterial peptide secretion.
2799	positive regulation of antibacterial peptide secretion	P	Any process that activates or increases the frequency, rate, or extent of antibacterial peptide secretion.
2800	regulation of antifungal peptide secretion	P	Any process that modulates the frequency, rate, or extent of antifungal peptide secretion.
2801	negative regulation of antifungal peptide secretion	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of antifungal peptide secretion.
2802	positive regulation of antifungal peptide secretion	P	Any process that activates or increases the frequency, rate, or extent of antifungal peptide secretion.
2803	positive regulation of antibacterial peptide production	P	Any process that activates or increases the frequency, rate, or extent of antibacterial peptide production.
2804	positive regulation of antifungal peptide production	P	Any process that activates or increases the frequency, rate, or extent of antifungal peptide production.
2805	regulation of antimicrobial peptide biosynthetic process	P	Any process that modulates the frequency, rate, or extent of antimicrobial peptide biosynthesis.
2806	negative regulation of antimicrobial peptide biosynthetic process	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of antimicrobial peptide biosynthesis.
2807	positive regulation of antimicrobial peptide biosynthetic process	P	Any process that activates or increases the frequency, rate, or extent of antimicrobial peptide biosynthesis.
2808	regulation of antibacterial peptide biosynthetic process	P	Any process that modulates the frequency, rate, or extent of antibacterial peptide biosynthesis.
2809	negative regulation of antibacterial peptide biosynthetic process	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of antibacterial peptide biosynthesis.
2810	regulation of antifungal peptide biosynthetic process	P	Any process that modulates the frequency, rate, or extent of antifungal peptide biosynthesis.
2811	negative regulation of antifungal peptide biosynthetic process	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of antifungal peptide biosynthesis.
2812	biosynthetic process of antibacterial peptides active against Gram-negative bacteria	P	The chemical reactions and pathways resulting in the formation of an antibacterial peptide with activity against Gram-negative bacteria.
2813	regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria	P	Any process that modulates the frequency, rate, or extent of biosynthesis of antibacterial peptides active against Gram-negative bacteria.
2814	negative regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of biosynthesis of antibacterial peptides active against Gram-negative bacteria.
2815	biosynthetic process of antibacterial peptides active against Gram-positive bacteria	P	The chemical reactions and pathways resulting in the formation of an antibacterial peptide with activity against Gram-positive bacteria.
2816	regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria	P	Any process that modulates the frequency, rate, or extent of biosynthesis of antibacterial peptides active against Gram-positive bacteria.
2817	negative regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of biosynthesis of antibacterial peptides active against Gram-positive bacteria.
2818	intracellular defense response	P	A physiological defense response which occurs intracellularly.
2819	regulation of adaptive immune response	P	Any process that modulates the frequency, rate, or extent of an adaptive immune response.
2820	negative regulation of adaptive immune response	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of an adaptive immune response.
2821	positive regulation of adaptive immune response	P	Any process that activates or increases the frequency, rate, or extent of an adaptive immune response.
2822	regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	P	Any process that modulates the frequency, rate, or extent of an adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains. An example of this process is found in the Gnathostomata.
2823	negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of an adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains. An example of this process is found in the Gnathostomata.
2824	positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	P	Any process that activates or increases the frequency, rate, or extent of an adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains. An example of this process is found in the Gnathostomata.
2825	regulation of T-helper 1 type immune response	P	Any process that modulates the frequency, rate, or extent of a T-helper 1 type immune response.
2826	negative regulation of T-helper 1 type immune response	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of a T-helper 1 type immune response.
2827	positive regulation of T-helper 1 type immune response	P	Any process that activates or increases the frequency, rate, or extent of a T-helper 1 type immune response.
2828	regulation of type 2 immune response	P	Any process that modulates the frequency, rate, or extent of a type 2 immune response.
2829	negative regulation of type 2 immune response	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of a type 2 immune response.
2830	positive regulation of type 2 immune response	P	Any process that activates or increases the frequency, rate, or extent of a type 2 immune response.
2831	regulation of response to biotic stimulus	P	Any process that modulates the frequency, rate, or extent of a response to biotic stimulus.
2832	negative regulation of response to biotic stimulus	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of a response to biotic stimulus.
2833	positive regulation of response to biotic stimulus	P	Any process that activates or increases the frequency, rate, or extent of a response to biotic stimulus.
2834	regulation of response to tumor cell	P	Any process that modulates the frequency, rate, or extent of a response to tumor cell.
2835	negative regulation of response to tumor cell	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of a response to tumor cell.
2836	positive regulation of response to tumor cell	P	Any process that activates or increases the frequency, rate, or extent of a response to tumor cell.
2837	regulation of immune response to tumor cell	P	Any process that modulates the frequency, rate, or extent of an immune response to tumor cell.
2838	negative regulation of immune response to tumor cell	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of an immune response to tumor cell.
2839	positive regulation of immune response to tumor cell	P	Any process that activates or increases the frequency, rate, or extent of an immune response to tumor cell.
2840	regulation of T cell mediated immune response to tumor cell	P	Any process that modulates the frequency, rate, or extent of a T cell mediated immune response to tumor cell.
2841	negative regulation of T cell mediated immune response to tumor cell	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of a T cell mediated immune response to tumor cell.
2842	positive regulation of T cell mediated immune response to tumor cell	P	Any process that activates or increases the frequency, rate, or extent of a T cell mediated immune response to tumor cell.
2843	regulation of tolerance induction to tumor cell	P	Any process that modulates the frequency, rate, or extent of tolerance induction to tumor cell.
2844	negative regulation of tolerance induction to tumor cell	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of tolerance induction to tumor cell.
2845	positive regulation of tolerance induction to tumor cell	P	Any process that activates or increases the frequency, rate, or extent of tolerance induction to tumor cell.
2846	regulation of T cell tolerance induction to tumor cell	P	Any process that modulates the frequency, rate, or extent of T cell tolerance induction to tumor cell.
2847	negative regulation of T cell tolerance induction to tumor cell	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell tolerance induction to tumor cell.
2848	positive regulation of T cell tolerance induction to tumor cell	P	Any process that activates or increases the frequency, rate, or extent of T cell tolerance induction to tumor cell.
2849	regulation of peripheral T cell tolerance induction	P	Any process that modulates the frequency, rate, or extent of peripheral T cell tolerance induction.
2850	negative regulation of peripheral T cell tolerance induction	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of peripheral T cell tolerance induction.
2851	positive regulation of peripheral T cell tolerance induction	P	Any process that activates or increases the frequency, rate, or extent of peripheral T cell tolerance induction.
2852	regulation of T cell mediated cytotoxicity directed against tumor cell target	P	Any process that modulates the frequency, rate, or extent of T cell mediated cytotoxicity directed against a tumor cell target.
2853	negative regulation of T cell mediated cytotoxicity directed against tumor cell target	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of T cell mediated cytotoxicity directed against a tumor cell target.
2854	positive regulation of T cell mediated cytotoxicity directed against tumor cell target	P	Any process that activates or increases the frequency, rate, or extent of T cell mediated cytotoxicity directed against a tumor cell target.
2855	regulation of natural killer cell mediated immune response to tumor cell	P	Any process that modulates the frequency, rate, or extent of natural killer cell mediated immune response to a tumor cell.
2856	negative regulation of natural killer cell mediated immune response to tumor cell	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of natural killer cell mediated immune response to a tumor cell.
2857	positive regulation of natural killer cell mediated immune response to tumor cell	P	Any process that activates or increases the frequency, rate, or extent of natural killer cell mediated immune response to a tumor cell.
2858	regulation of natural killer cell mediated cytotoxicity directed against tumor cell target	P	Any process that modulates the frequency, rate, or extent of natural killer cell mediated cytotoxicity directed against tumor cell target.
2859	negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of natural killer cell mediated cytotoxicity directed against tumor cell target.
2860	positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target	P	Any process that activates or increases the frequency, rate, or extent of natural killer cell mediated cytotoxicity directed against tumor cell target.
2861	regulation of inflammatory response to antigenic stimulus	P	Any process that modulates the frequency, rate, or extent of an inflammatory response to an antigenic stimulus.
2862	negative regulation of inflammatory response to antigenic stimulus	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of an inflammatory response to an antigenic stimulus.
2863	positive regulation of inflammatory response to antigenic stimulus	P	Any process that activates or increases the frequency, rate, or extent of an inflammatory response to an antigenic stimulus.
2864	regulation of acute inflammatory response to antigenic stimulus	P	Any process that modulates the frequency, rate, or extent of an acute inflammatory response to an antigenic stimulus.
2865	negative regulation of acute inflammatory response to antigenic stimulus	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of an acute inflammatory response to an antigenic stimulus.
2866	positive regulation of acute inflammatory response to antigenic stimulus	P	Any process that activates or increases the frequency, rate, or extent of an acute inflammatory response to an antigenic stimulus.
2867	regulation of B cell deletion	P	Any process that modulates the frequency, rate, or extent of B cell deletion.
2868	negative regulation of B cell deletion	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of B cell deletion.
2869	positive regulation of B cell deletion	P	Any process that activates or increases the frequency, rate, or extent of B cell deletion.
2870	T cell anergy	P	Any process contributing to anergy in T cells, a state of functional inactivation which is part of T cell tolerance induction.
2871	regulation of natural killer cell tolerance induction	P	Any process that modulates the frequency, rate, or extent of natural killer cell tolerance induction.
2872	negative regulation of natural killer cell tolerance induction	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of natural killer cell tolerance induction.
2873	positive regulation of natural killer cell tolerance induction	P	Any process that activates or increases the frequency, rate, or extent of natural killer cell tolerance induction.
2874	regulation of chronic inflammatory response to antigenic stimulus	P	Any process that modulates the frequency, rate, or extent of a chronic inflammatory response to an antigenic stimulus.
2875	negative regulation of chronic inflammatory response to antigenic stimulus	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of a chronic inflammatory response to an antigenic stimulus.
2876	positive regulation of chronic inflammatory response to antigenic stimulus	P	Any process that activates or increases the frequency, rate, or extent of a chronic inflammatory response to an antigenic stimulus.
2877	regulation of acute inflammatory response to non-antigenic stimulus	P	Any process that modulates the frequency, rate, or extent of an acute inflammatory response to a non-antigenic stimulus.
2878	negative regulation of acute inflammatory response to non-antigenic stimulus	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of an acute inflammatory response to a non-antigenic stimulus.
2879	positive regulation of acute inflammatory response to non-antigenic stimulus	P	Any process that activates or increases the frequency, rate, or extent of an acute inflammatory response to a non-antigenic stimulus.
2880	regulation of chronic inflammatory response to non-antigenic stimulus	P	Any process that modulates the frequency, rate, or extent of a chronic inflammatory response to a non-antigenic stimulus.
2881	negative regulation of chronic inflammatory response to non-antigenic stimulus	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of a chronic inflammatory response to a non-antigenic stimulus.
2882	positive regulation of chronic inflammatory response to non-antigenic stimulus	P	Any process that activates or increases the frequency, rate, or extent of a chronic inflammatory response to a non-antigenic stimulus.
2883	regulation of hypersensitivity	P	Any process that modulates the frequency, rate, or extent of hypersensitivity.
2884	negative regulation of hypersensitivity	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of hypersensitivity.
2885	positive regulation of hypersensitivity	P	Any process that activates or increases the frequency, rate, or extent of hypersensitivity.
2886	regulation of myeloid leukocyte mediated immunity	P	Any process that modulates the frequency, rate, or extent of myeloid leukocyte mediated immunity.
2887	negative regulation of myeloid leukocyte mediated immunity	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of myeloid leukocyte mediated immunity.
2888	positive regulation of myeloid leukocyte mediated immunity	P	Any process that activates or increases the frequency, rate, or extent of myeloid leukocyte mediated immunity.
2889	regulation of immunoglobulin mediated immune response	P	Any process that modulates the frequency, rate, or extent of an immunoglobulin mediated immune response.
2890	negative regulation of immunoglobulin mediated immune response	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of an immunoglobulin mediated immune response.
2891	positive regulation of immunoglobulin mediated immune response	P	Any process that activates or increases the frequency, rate, or extent of an immunoglobulin mediated immune response.
2892	regulation of type II hypersensitivity	P	Any process that modulates the frequency, rate, or extent of type II hypersensitivity.
2893	negative regulation of type II hypersensitivity	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of type II hypersensitivity.
2894	positive regulation of type II hypersensitivity	P	Any process that activates or increases the frequency, rate, or extent of type II hypersensitivity.
2895	regulation of central B cell tolerance induction	P	Any process that modulates the frequency, rate, or extent of central B cell tolerance induction.
2896	negative regulation of central B cell tolerance induction	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of central B cell tolerance induction.
2897	positive regulation of central B cell tolerance induction	P	Any process that activates or increases the frequency, rate, or extent of central B cell tolerance induction.
2898	regulation of central B cell deletion	P	Any process that modulates the frequency, rate, or extent of central B cell deletion.
2899	negative regulation of central B cell deletion	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of central B cell deletion.
2900	positive regulation of central B cell deletion	P	Any process that activates or increases the frequency, rate, or extent of central B cell deletion.
2901	mature B cell apoptotic process	P	Any apoptotic process in a B cell that is mature, having left the bone marrow.
2902	regulation of B cell apoptotic process	P	Any process that modulates the frequency, rate, or extent of B cell apoptotic process.
2903	negative regulation of B cell apoptotic process	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of B cell apoptotic process.
2904	positive regulation of B cell apoptotic process	P	Any process that activates or increases the frequency, rate, or extent of B cell apoptotic process.
2905	regulation of mature B cell apoptotic process	P	Any process that modulates the frequency, rate, or extent of mature B cell apoptotic process.
2906	negative regulation of mature B cell apoptotic process	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of mature B cell apoptotic process.
2907	positive regulation of mature B cell apoptotic process	P	Any process that activates or increases the frequency, rate, or extent of mature B cell apoptotic process.
2908	regulation of peripheral B cell deletion	P	Any process that modulates the frequency, rate, or extent of peripheral B cell deletion.
2909	negative regulation of peripheral B cell deletion	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of peripheral B cell deletion.
2910	positive regulation of peripheral B cell deletion	P	Any process that activates or increases the frequency, rate, or extent of peripheral B cell deletion.
2911	regulation of lymphocyte anergy	P	Any process that modulates the frequency, rate, or extent of lymphocyte anergy.
2912	negative regulation of lymphocyte anergy	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of lymphocyte anergy.
2913	positive regulation of lymphocyte anergy	P	Any process that activates or increases the frequency, rate, or extent of lymphocyte anergy.
2914	regulation of central B cell anergy	P	Any process that modulates the frequency, rate, or extent of central B cell anergy.
2915	negative regulation of central B cell anergy	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of central B cell anergy.
2916	positive regulation of central B cell anergy	P	Any process that activates or increases the frequency, rate, or extent of central B cell anergy.
2917	regulation of peripheral B cell anergy	P	Any process that modulates the frequency, rate, or extent of peripheral B cell anergy.
2918	negative regulation of peripheral B cell anergy	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of peripheral B cell anergy.
2919	positive regulation of peripheral B cell anergy	P	Any process that activates or increases the frequency, rate, or extent of peripheral B cell anergy.
2920	regulation of humoral immune response	P	Any process that modulates the frequency, rate, or extent of a humoral immune response.
2921	negative regulation of humoral immune response	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of a humoral immune response.
2922	positive regulation of humoral immune response	P	Any process that activates or increases the frequency, rate, or extent of a humoral immune response.
2923	regulation of humoral immune response mediated by circulating immunoglobulin	P	Any process that modulates the frequency, rate, or extent of a humoral immune response mediated by circulating immunoglobulin.
2924	negative regulation of humoral immune response mediated by circulating immunoglobulin	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of a humoral immune response mediated by circulating immunoglobulin.
2925	positive regulation of humoral immune response mediated by circulating immunoglobulin	P	Any process that activates or increases the frequency, rate, or extent of a humoral immune response mediated by circulating immunoglobulin.
2926	tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridine biosynthesis.	P	The process whereby a wobble base uridine residue in a tRNA is modified to 5-methoxycarbonylmethyl-2-thiouridine.
2927	archaeosine-tRNA biosynthetic process	P	The chemical reactions and pathways involved in the biosynthesis of archaeosine, an archaea-specific modified base found at position 15 in the D-loop of certain archaeal tRNAs.
2929	MECO complex	C	A highly stable complex composed of the ATAC complex and the mediator complex (also called TRAP or MED). MECO binds and regulates the transcription of a subset of non-coding RNAs transcribed by RNA polymerase II.
2930	trabecular meshwork development	P	The progression of the trabecular meshwork over time, from its formation to the mature structure. The trabecular meshwork is a fenestrated endothelial-like tissue situated at the intersection of the cornea and the iris. The trabecular meshwork provides drainage for the aqueous humor.
2931	response to ischemia	P	Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a inadequate blood supply.
2932	tendon sheath development	P	The process whose specific outcome is the progression of a tendon sheath over time, from its formation to the mature structure. A tendon sheath is a layer of membrane around a tendon. It permits the tendon to move.
2933	lipid hydroxylation	P	The covalent attachment of a hydroxyl group to one or more fatty acids in a lipid.
2934	desmosome organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a desmosome. A desmosome is a patch-like intercellular junction found in vertebrate tissues, consisting of parallel zones of two cell membranes, separated by an space of 25-35 nm, and having dense fibrillar plaques in the subjacent cytoplasm.
2935	tRNA (adenine-C2-)-methyltransferase activity	F	Catalysis of the reaction: 2 S-adenosyl-L-methionine + adenine(37) in tRNA = S-adenosyl-L-homocysteine + 5'-deoxyadenosine + L-methionine + C2-methyladenine(37) in a tRNA.
2936	bradykinin biosynthetic process	P	The chemical reactions and pathways resulting in the formation of the peptide hormone bradykinin.
2937	tRNA 4-thiouridine biosynthesis	P	The processes whereby a uridine residue in a tRNA is converted to 4-thiouridine. Typically 4-thiouridine is found at position 8, in many transfer RNAs.
2938	tRNA guanine ribose methylation	P	The process whereby a guanosine residue in a tRNA is methylated on the 2'-hydroxyl group of the ribose moiety.
2939	tRNA N1-guanine methylation	P	The process whereby a guanine in tRNA is methylated at position N1 of the guanine.
2940	tRNA N2-guanine methylation	P	The process whereby a guanine in a tRNA is methylated at the N2 position of guanine.
2941	synoviocyte proliferation	P	The multiplication or reproduction of synoviocytes by cell division, resulting in the expansion of their population. A synoviocyte is a fibroblast-like cell found in synovial tissues.
2942	tRNA m2,2-guanine biosynthesis	P	The process whereby a guanine residue in a transfer RNA is methylated twice at the N2 position.
2943	tRNA dihydrouridine synthesis	P	The process whereby a uridine in a transfer RNA is converted to dihydrouridine.
2944	cyclin K-CDK12 complex	C	A protein complex consisting of cyclin Kand cyclin-dependent kinase 12 (CDK12). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner.
2945	cyclin K-CDK13 complex	C	A protein complex consisting of cyclin Kand cyclin-dependent kinase 13 (CDK13). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner.
2946	tRNA C5-cytosine methylation	P	The process whereby a cytosine in a tRNA is methylated at position 5 of the cytosine.
2947	tumor necrosis factor receptor superfamily complex	C	A receptor complex that contains one or more members of the tumor necrosis factor (TNF) receptor superfamily.
2948	archaeosine synthase activity	F	Catalysis of the reaction: L-glutamine + 7-cyano-7-carbaguanine15 in tRNA + H2O = L-glutamate + archaeine15 in tRNA.
2949	tRNA threonylcarbamoyladenosine modification	P	The attachment of a carbonyl group and a threonine to the amino group of the adenine residue immediately 3' of the anticodon, in tRNAs that decode ANN codons (where N is any base).
2950	ceramide phosphoethanolamine synthase activity	F	Catalysis of the reaction: CDP-ethanolamine + a ceramide = CMP + a ceramide phosphoethanolamine.
3002	regionalization	P	The pattern specification process that results in the subdivision of an axis or axes in space to define an area or volume in which specific patterns of cell differentiation will take place or in which cells interpret a specific environment.
3003	follicular fluid formation in ovarian follicle antrum involved in fused antrum stage	P	The ovulation cycle process in which one central cavity separating the oocyte/cumulus complex from mural granulosa and theca cells is formed as part of the fused antrum stage of oogenesis.
3004	follicular fluid formation in ovarian follicle antrum involved in distinct antral spaces stage	P	The menstrual cycle process in which one central cavity separating the oocyte/cumulus complex from mural granulosa and theca cells is formed as part of the antral spaces stage of oogenesis.
3005	follicular fluid formation in ovarian follicle antrum involved in scattered antral spaces stage	P	The menstrual cycle process in which one central cavity separating the oocyte/cumulus complex from mural granulosa and theca cells is formed as part of the scattered antral spaces stage of oogenesis.
3006	developmental process involved in reproduction	P	A developmental process in which a progressive change in the state of some part of an organism specifically contributes to its ability to form offspring.
3007	heart morphogenesis	P	The developmental process in which the heart is generated and organized. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood.
3008	system process	P	A multicellular organismal process carried out by any of the organs or tissues in an organ system. An organ system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a biological objective.
3009	skeletal muscle contraction	P	A process in which force is generated within skeletal muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. In the skeletal muscle, the muscle contraction takes advantage of an ordered sarcomeric structure and in most cases it is under voluntary control.
3010	voluntary skeletal muscle contraction	P	A process in which force is generated within voluntary skeletal muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. In the voluntary skeletal muscle, the muscle contraction takes advantage of an ordered sarcomeric structure and it is under voluntary control. Voluntary skeletal muscle is skeletal muscle that is under conscious control.
3011	involuntary skeletal muscle contraction	P	A process in which force is generated within involuntary skeletal muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. Involuntary skeletal muscle is skeletal muscle that is not under conscious control.
3012	muscle system process	P	A organ system process carried out at the level of a muscle. Muscle tissue is composed of contractile cells or fibers.
3013	circulatory system process	P	A organ system process carried out by any of the organs or tissues of the circulatory system. The circulatory system is an organ system that moves extracellular fluids to and from tissue within a multicellular organism.
3014	renal system process	P	A organ system process carried out by any of the organs or tissues of the renal system. The renal system maintains fluid balance, and contributes to electrolyte balance, acid/base balance, and disposal of nitrogenous waste products. In humans, the renal system comprises a pair of kidneys, a pair of ureters, urinary bladder, urethra, sphincter muscle and associated blood vessels; in other species, the renal system may comprise related structures (e.g., nephrocytes and malpighian tubules in Drosophila).
3015	heart process	P	A circulatory system process carried out by the heart. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood.
3016	respiratory system process	P	A system process carried out by the organs and tissues of the respiratory system. The respiratory system is an organ system responsible for respiratory gaseous exchange.
3017	lymph circulation	P	The flow of lymph through the body of an animal.
3018	vascular process in circulatory system	P	A circulatory process that occurs at the level of the vasculature.
3019	central nervous system control of baroreceptor feedback	P	The neurological process in which nerve impulses arising in the aorta or the carotid sinuses travel to the medulla and reach the nucleus of tractus solaris.
3020	detection of reduced oxygen by chemoreceptor signaling	P	The process in which information about the levels of oxygen are received and are converted to a molecular signal by chemoreceptors in the carotid bodies and the aortic bodies.
3021	detection of increased carbon dioxide by chemoreceptor signaling	P	The process in which information about the levels of carbon dioxide are received and are converted to a molecular signal by chemoreceptors in the carotid bodies and the aortic bodies.
3022	detection of pH by chemoreceptor signaling	P	The process in which information about the levels of hydrogen ions are received and are converted to a molecular signal by chemoreceptors.
3023	baroreceptor detection of increased arterial stretch	P	The series of events by which an increase in diameter of an artery is detected and converted to a molecular signal.
3024	baroreceptor detection of decreased arterial stretch	P	The series of events by which a decrease in diameter of an artery is detected and converted to a molecular signal.
3025	regulation of systemic arterial blood pressure by baroreceptor feedback	P	The neural regulation of blood pressure in which baroreceptors sense the amount of stretch occurring in vessels and respond to the input via central nervous system control.
3026	regulation of systemic arterial blood pressure by aortic arch baroreceptor feedback	P	The process that modulates blood pressure by sensing the amount of stretch occurring in the aorta and responding to the input via central nervous system control.
3027	regulation of systemic arterial blood pressure by carotid body chemoreceptor signaling	P	The process that modulates blood pressure by the action of chemoreceptors found in the carotid bodies and their resultant modulation of the vasomotor center. Chemoreceptors respond to oxygen, carbon dioxide and hydrogen ions.
3028	regulation of systemic arterial blood pressure by aortic body chemoreceptor signaling	P	The process that modulates blood pressure by the action of chemoreceptors found in the aortic bodies and their resultant modulation of the vasomotor center. Chemoreceptors respond to oxygen, carbon dioxide and hydrogen ions.
3029	detection of hypoxic conditions in blood by carotid body chemoreceptor signaling	P	The process in which information about a lack of oxygen are received and are converted to a molecular signal by chemoreceptors in the carotid bodies.
3030	detection of hydrogen ion	P	The series of events in which a hydrogen ion stimulus is received by a cell and converted into a molecular signal.
3031	detection of carbon dioxide	P	The series of events in which a carbon dioxide stimulus is received by a cell and converted into a molecular signal.
3032	detection of oxygen	P	The series of events in which an oxygen stimulus is received by a cell and converted into a molecular signal.
3033	detection of hypoxic conditions in blood by aortic body chemoreceptor signaling	P	The process in which information about a lack of oxygen are received and are converted to a molecular signal by chemoreceptors in the aortic bodies.
3034	detection of increased carbon dioxide by aortic body chemoreceptor signaling	P	The process in which information about the levels of carbon dioxide are received and are converted to a molecular signal by chemoreceptors in an aortic body.
3035	detection of increased carbon dioxide by carotid body chemoreceptor signaling	P	The process in which information about the levels of carbon dioxide are received and are converted to a molecular signal by chemoreceptors in a carotid body.
3036	detection of pH by aortic body chemoreceptor signaling	P	The process in which information about the levels of hydrogen ions are received and are converted to a molecular signal by chemoreceptors in an aortic body.
3037	detection of pH by carotid body chemoreceptor signaling	P	The process in which information about the levels of hydrogen ions are received and are converted to a molecular signal by chemoreceptors in a carotid body.
3038	detection of reduced oxygen by aortic body chemoreceptor signaling	P	The process in which information about the levels of oxygen are received and are converted to a molecular signal by chemoreceptors in an aortic body.
3039	detection of reduced oxygen by carotid body chemoreceptor signaling	P	The process in which information about the levels of oxygen are received and are converted to a molecular signal by chemoreceptors in a carotid body.
3040	excitation of vasomotor center by aortic body chemoreceptor signaling	P	The process in which the molecular signal from an aortic body is relayed to the vasomotor center, causing it to signal an increase arterial pressure.
3041	excitation of vasomotor center by carotid body chemoreceptor signaling	P	The process in which the molecular signal from a carotid body is relayed to the vasomotor center, causing it to signal an increase arterial pressure.
3042	vasoconstriction of artery involved in carotid body chemoreceptor response to lowering of systemic arterial blood pressure	P	A process that is triggered by carotid body-vasomotor excitation and results in a decrease in the diameter of an artery during the chemoreceptor response to decreased blood pressure.
3043	vasoconstriction of artery involved in aortic body chemoreceptor response to lowering of systemic arterial blood pressure	P	A process that is triggered by aortic body-vasomotor excitation and results in a decrease in the diameter of an artery during the chemoreceptor response to decreased blood pressure.
3044	regulation of systemic arterial blood pressure mediated by a chemical signal	P	The regulation of blood pressure mediated by biochemical signaling: hormonal, autocrine or paracrine.
3045	regulation of systemic arterial blood pressure by physical factors	P	The regulation of blood pressure mediated by detection of forces within the circulatory system.
3046	regulation of systemic arterial blood pressure by stress relaxation	P	The intrinsic circulatory process resulting from stress relaxation that modulates the force with which blood travels through the systemic arterial circulatory system. Stress relaxation is the adaptation of vessels to a new size as a result of changes in pressure in storage areas such as veins, the liver, the spleen, and the lungs.
3047	regulation of systemic arterial blood pressure by epinephrine	P	The regulation of blood pressure mediated by the catecholamine signaling molecule epinephrine.
3048	regulation of systemic arterial blood pressure by norepinephrine	P	The regulation of blood pressure mediated by the catecholamine signaling molecule norepinephrine.
3049	regulation of systemic arterial blood pressure by capillary fluid shift	P	The intrinsic circulatory process resulting from capillary fluid shift that modulates the force with which blood travels through the systemic arterial circulatory system. Capillary fluid shift is the movement of fluid across the capillary membrane between the blood and the interstitial fluid compartment.
3050	regulation of systemic arterial blood pressure by atrial natriuretic peptide	P	The regulation of blood pressure mediated by the signaling molecule atrial natriuretic peptide.
3051	angiotensin-mediated drinking behavior	P	The drinking behavior that is mediated by the action of angiotensin in the brain. Angiotensin stimulates the brain centers that control thirst.
3052	circadian regulation of systemic arterial blood pressure	P	Any process in which an organism modulates its blood pressure at different values with a regularity of approximately 24 hours.
3053	circadian regulation of heart rate	P	Any process in which an organism modulates its heart rate at different values with a regularity of approximately 24 hours.
3054	circadian regulation of systemic arterial blood pressure by the suprachiasmatic nucleus	P	The process in which the suprachiasmatic nucleus modulates blood pressure at different values with a regularity of approximately 24 hours.
3055	circadian regulation of heart rate by the suprachiasmatic nucleus	P	The process in which the suprachiasmatic nucleus modulates heart rate at different values with a regularity of approximately 24 hours.
3056	regulation of vascular smooth muscle contraction	P	Any process that increases the frequency, rate or extent of vascular smooth muscle contraction.
3057	regulation of the force of heart contraction by chemical signal	P	The regulation of the force of heart muscle contraction mediated by chemical signaling, hormonal, autocrine or paracrine.
3058	hormonal regulation of the force of heart contraction	P	The process in which the hormones modulates the force of heart muscle contraction. A hormone is one of a group of substances formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells, in the same organism, upon which they have a specific regulatory action.
3059	positive regulation of the force of heart contraction by epinephrine	P	The process in which the secretion of epinephrine into the bloodstream or released from nerve endings modulates the force of heart muscle contraction.
3060	negative regulation of the force of heart contraction by acetylcholine	P	The process in which acetylcholine released from vagus nerve endings binds to muscarinic receptors and decreases the force of heart muscle contraction.
3061	positive regulation of the force of heart contraction by norepinephrine	P	The process in which the secretion of norepinephrine into the bloodstream or released from nerve endings modulates the force of heart musclecontraction.
3062	regulation of heart rate by chemical signal	P	The regulation of the rate of heart contraction mediated by chemical signaling, hormonal, autocrine or paracrine.
3063	negative regulation of heart rate by acetylcholine	P	The process in which acetylcholine released from vagus nerve endings binds to muscarinic receptors on the pacemaker cells and decreases the rate of heart muscle contraction.
3064	regulation of heart rate by hormone	P	The process in which the hormones modulates the rate of heart muscle contraction. A hormone is one of a group of substances formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells, in the same organism, upon which they have a specific regulatory action.
3065	positive regulation of heart rate by epinephrine	P	The process in which the secretion of epinephrine into the bloodstream or released from nerve endings increases the rate of heart muscle contraction.
3066	positive regulation of heart rate by norepinephrine	P	The process in which the secretion of norepinephrine into the bloodstream or released from nerve endings increases the rate of heart muscle contraction.
3067	circadian regulation of systemic arterial blood pressure by hormone	P	The process in which hormones modulate the force with which blood passes through the circulatory system contributing to different values of blood pressure oscillating with a regularity of approximately 24 hours. A hormone is one of a group of substances formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells, in the same organism, upon which they have a specific regulatory action.
3068	regulation of systemic arterial blood pressure by acetylcholine	P	The regulation of blood pressure mediated by acetylcholine signaling. Acetylcholine is an acetic acid ester of the organic base choline and functions as a neurotransmitter.
3069	vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure	P	The process in which acetylcholine signaling causes vasodilation, resulting in a change in blood pressure.
3070	regulation of systemic arterial blood pressure by neurotransmitter	P	The regulation of blood pressure mediated by a neurotransmitter. A neurotransmitter is any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell.
3071	renal system process involved in regulation of systemic arterial blood pressure	P	Renal process that modulates the force with which blood travels through the circulatory system. The process is controlled by a balance of processes that increase pressure and decrease pressure.
3072	renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure	P	The renal process that modulates the force with which blood travels through the circulatory system, by impeding blood flow through the peripheral vasculature.
3073	regulation of systemic arterial blood pressure	P	The process that modulates the force with which blood travels through the systemic arterial circulatory system. The process is controlled by a balance of processes that increase pressure and decrease pressure.
3075	renal vasodilation of the peripheral vascular system involved in regulation of systemic arterial blood pressure	P	The renal process that modulates the force with which blood travels through the circulatory system, by vasodilation of the peripheral vascular system.
3081	regulation of systemic arterial blood pressure by renin-angiotensin	P	The process in which renin-angiotensin modulates the force with which blood passes through the circulatory system.
3083	negative regulation of renal output by angiotensin	P	The process in which angiotensin directly decreases the rate of natriuresis and diuresis in the kidney.
3084	positive regulation of systemic arterial blood pressure	P	The process that increases the force with which blood travels through the systemic arterial circulatory system.
3085	negative regulation of systemic arterial blood pressure	P	The process that reduces the force with which blood travels through the systemic arterial circulatory system.
3086	regulation of systemic arterial blood pressure by local renal renin-angiotensin	P	The process in which angiotensinogen metabolites in the kidney modulate the force with which blood passes through the renal circulatory system. The process begins when renin cleaves angiotensinogen.
3087	positive regulation of the force of heart contraction by neuronal epinephrine	P	The process in which the release of epinephrine from nerve endings modulates the force of heart muscle contraction.
3088	positive regulation of the force of heart contraction by circulating epinephrine	P	The process in which the secretion of epinephrine into the bloodstream modulates the force of heart muscle contraction.
3089	positive regulation of the force of heart contraction by circulating epinephrine-norepinephrine	P	Any process that increases the force with which the cardiac muscles of the heart pump blood through the circulatory system as a result of the presence of epinephrine or norepinephrine in the bloodstream.
3090	positive regulation of the force of heart contraction by neuronal epinephrine-norepinephrine	P	Any process that increases the force with which the cardiac muscles of the heart pump blood through the circulatory system as a result of the presence of epinephrine or norepinephrine released from the nerve endings.
3091	renal water homeostasis	P	Renal process involved in the maintenance of an internal steady state of water in the body.
3092	renal water retention	P	The process in which renal water excretion is decreased.
3093	regulation of glomerular filtration	P	Any process that modulates the frequency, rate or extent of glomerular filtration. Glomerular filtration is the process in which blood is filtered by the glomerulus into the renal tubule.
3094	glomerular filtration	P	The process in which plasma is filtered through the glomerular membrane which consists of capillary endothelial cells, the basement membrane, and epithelial cells. The glomerular filtrate is the same as plasma except it has no significant amount of protein.
3095	pressure natriuresis	P	The process in which the volume of blood increases renal pressure and thereby results in both an increase in urine volume (diuresis) and an increase in the amount of sodium excreted in the urine (natriuresis).
3096	renal sodium ion transport	P	The directed movement of sodium ions (Na+) by the kidney.
3097	renal water transport	P	The directed movement of water (H2O) by the kidney.
3098	tubuloglomerular feedback	P	The process in which blood volume is regulated due to a change in the rate of glomerular filtration. This is accomplished by a feedback mechanism that senses changes in the juxtaglomerular apparatus.
3099	positive regulation of the force of heart contraction by chemical signal	P	Any process which increases the force of heart muscle contraction mediated by chemical signaling, hormonal, autocrine or paracrine.
3100	regulation of systemic arterial blood pressure by endothelin	P	The process in which endothelin modulates the force with which blood passes through the circulatory system. Endothelin is a hormone that is released by the endothelium, and it is a vasoconstrictor.
3101	regulation of systemic arterial blood pressure by circulatory epinephrine-norepinephrine	P	The process in which epinephrine-norepinephrine modulate the force with which blood passes through the circulatory system.
3104	positive regulation of glomerular filtration	P	Any process that activates or increases the frequency, rate or extent of glomerular filtration. Glomerular filtration is the processs whereby blood is filtered by the glomerulus into the renal tubule.
3105	negative regulation of glomerular filtration	P	Any process that stops, prevents, or reduces the frequency, rate or extent of glomerular filtration. Glomerular filtration is the processs whereby blood is filtered by the glomerulus into the renal tubule.
3106	negative regulation of glomerular filtration by angiotensin	P	The process in which angiotensin directly decreases the rate of glomerular filtration in the kidney. Glomerular filtration is the processs whereby blood is filtered by the glomerulus into the renal tubule.
3108	negative regulation of the force of heart contraction by chemical signal	P	Any process which decreases the force of heart muscle contraction mediated by chemical signaling, hormonal, autocrine or paracrine.
3109	positive regulation of the force of heart contraction by circulating norepinephrine	P	The process in which the secretion of norepinephrine into the bloodstream modulates the force of heart muscle contraction.
3110	positive regulation of the force of heart contraction by neuronal norepinephrine	P	The process in which the release of norepinephrine from nerve endings modulates the force of heart muscle contraction.
3111	positive regulation of heart rate by circulating epinephrine	P	The process in which the secretion of epinephrine into the bloodstream increases the rate of heart muscle contraction.
3112	positive regulation of heart rate by neuronal epinephrine	P	The process in which the secretion of epinephrine from nerve endings increases the rate of heart muscle contraction.
3113	positive regulation of heart rate by neuronal norepinephrine	P	The process in which the secretion of norepinephrine released from nerve endings increases the rate of heart muscle contraction.
3114	positive regulation of heart rate by circulating norepinephrine	P	The process in which the secretion of norepinephrine into the bloodstream increases the rate of heart muscle contraction.
3115	regulation of vasoconstriction by epinephrine	P	Any process that modulates the frequency, rate or extent of reductions in the diameter of blood vessels as a result of secretion of epinephrine into the bloodstream or released by nerve endings.
3116	regulation of vasoconstriction by norepinephrine	P	Any process that modulates the frequency, rate or extent of reductions in the diameter of blood vessels as a result of secretion of norepinephrine into the bloodstream or released by nerve endings.
3117	regulation of vasoconstriction by circulating norepinephrine	P	Any process that modulates the frequency, rate or extent of reductions in the diameter of blood vessels as a result of secretion of norepinephrine into the bloodstream.
3118	regulation of vasoconstriction by neuronal norepinephrine	P	Any process that modulates the frequency, rate or extent of reductions in the diameter of blood vessels as a result of norepinephrine released by nerve endings.
3119	regulation of vasoconstriction by neuronal epinephrine	P	Any process that modulates the frequency, rate or extent of reductions in the diameter of blood vessels as a result of epinephrine released by nerve endings.
3120	regulation of vasoconstriction by circulating epinephrine	P	Any process that modulates the frequency, rate or extent of reductions in the diameter of blood vessels as a result of secretion of epinephrine into the bloodstream.
3121	regulation of vasodilation by epinephrine	P	Any process that modulates the frequency, rate or extent of increases in the diameter of blood vessels as a result of secretion of epinephrine into the bloodstream or released by nerve endings.
3122	regulation of vasodilation by norepinephrine	P	Any process that modulates the frequency, rate or extent of increases in the diameter of blood vessels as a result of secretion of norepinephrine into the bloodstream or released by nerve endings.
3123	regulation of vasodilation by circulating epinephrine	P	Any process that modulates the frequency, rate or extent of increases in the diameter of blood vessels as a result of secretion of epinephrine into the bloodstream.
3124	regulation of vasodilation by neuronal epinephrine	P	Any process that modulates the frequency, rate or extent of increases in the diameter of blood vessels as a result of epinephrine released by nerve endings.
3125	regulation of vasodilation by circulating norepinephrine	P	Any process that modulates the frequency, rate or extent of increases in the diameter of blood vessels as a result of secretion of norepinephrine into the bloodstream.
3126	regulation of vasodilation by neuronal norepinephrine	P	Any process that modulates the frequency, rate or extent of increases in the diameter of blood vessels as a result of norepinephrine released by nerve endings.
3127	detection of nodal flow	P	The series of events by which an endogenous stimulus is received by a cilium on a cell and converted to a molecular signal contributing to left/right asymmetry.
3128	heart field specification	P	The process that results in the delineation of a specific region of the lateral mesoderm into the area in which the heart will develop.
3129	heart induction	P	The close range interaction between mesoderm and endoderm or ectoderm that causes cells to change their fates and specify the development of the heart.
3130	BMP signaling pathway involved in heart induction	P	A series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, which contributes to heart induction.
3131	mesodermal-endodermal cell signaling	P	Any process that mediates the transfer of information from mesodermal cells to endodermal cells.
3132	mesodermal-endodermal cell signaling involved in heart induction	P	Any process that mediates the transfer of information from mesodermal cells to endodermal cells that contributes to heart induction.
3133	endodermal-mesodermal cell signaling	P	Any process that mediates the transfer of information from endodermal cells to mesodermal cells.
3134	endodermal-mesodermal cell signaling involved in heart induction	P	Any process that mediates the transfer of information from endodermal cells to mesodermal cells that contributes to heart induction.
3135	fibroblast growth factor receptor signaling pathway involved in heart induction	P	The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands that contributes to heart induction.
3136	negative regulation of heart induction by canonical Wnt signaling pathway	P	Any canonical Wnt signaling that decreases the rate, frequency or extent of heart induction.
3137	Notch signaling pathway involved in heart induction	P	The series of molecular signals initiated by binding of an extracellular ligand to a Notch receptor on the surface of the target cell that contributes to heart induction.
3138	primary heart field specification	P	The process that results in the delineation of a specific region of the lateral mesoderm into the area which will form the primary beating heart tube. In mammals the primary heart field gives rise to the left ventricle.
3139	secondary heart field specification	P	The process that results in the delineation of a specific region of the lateral mesoderm into the area which will form the majority of the mesodermal component of the right ventricle, arterial pole (outflow tract) and venous pole (inflow tract).
3140	determination of left/right asymmetry in lateral mesoderm	P	The establishment of the lateral mesoderm with respect to the left and right halves.
3142	cardiogenic plate morphogenesis	P	The process in which the anatomical structures of the cardiogenic plate are generated and organized. The cardiogenic plate is the first recognizable structure derived from the heart field.
3143	embryonic heart tube morphogenesis	P	The process in which the anatomical structures of the embryonic heart tube are generated and organized. The embryonic heart tube is an epithelial tube that will give rise to the mature heart.
3144	embryonic heart tube formation	P	The process that gives rise to the embryonic heart tube. This process pertains to the initial formation of a structure from unspecified parts. The embryonic heart tube is an epithelial tube that will give rise to the mature heart.
3145	embryonic heart tube formation via epithelial folding	P	The process that gives rise to the embryonic heart tube by the cells of the heart field along a linear axis.
3146	heart jogging	P	The morphogenetic process in which the heart cone is displaced to the left with respect to the vector of the anterior-posterior axis.
3147	neural crest cell migration involved in heart formation	P	The characteristic movement of a cell from the dorsal ridge of the neural tube towards the heart and that contributes to heart formation.
3148	outflow tract septum morphogenesis	P	The process in which the anatomical structures of the outflow tract septum are generated and organized. The outflow tract septum is a partition in the outflow tract.
3149	membranous septum morphogenesis	P	The process in which the membranous septum is generated and organized. The membranous septum is the upper part of ventricular septum.
3150	muscular septum morphogenesis	P	The process in which the muscular septum is generated and organized. The muscular septum is the lower part of the ventricular septum.
3151	outflow tract morphogenesis	P	The process in which the anatomical structures of the outflow tract are generated and organized. The outflow tract is the portion of the heart through which blood flows into the arteries.
3152	morphogenesis of an epithelial fold involved in embryonic heart tube formation	P	The morphogenetic process in which an epithelial sheet bends along a linear axis, contributing to embryonic heart tube formation.
3153	closure of embryonic heart tube	P	Creation of the central hole of the embryonic heart tube by sealing the edges of an epithelial fold.
3154	BMP signaling pathway involved in determination of left/right symmetry	P	A series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, which contributes to the determination of left/right symmetry.
3155	BMP signaling pathway involved in determination of lateral mesoderm left/right asymmetry	P	A series of molecular signals generated as a consequence of any member of the BMP (bone morphogenetic protein) family binding to a cell surface receptor that contributes to the determination of lateral mesoderm left/right asymmetry.
3156	regulation of animal organ formation	P	Any process that modulates the rate, frequency or extent of animal organ formation. Organ formation is the process pertaining to the initial formation of an organ from unspecified parts. The process begins with the specific processes that contribute to the appearance of the discrete structure, such as inductive events, and ends when the structural rudiment of the organ is recognizable, such as a condensation of mesenchymal cells into the organ rudiment.
3157	endocardium development	P	The process whose specific outcome is the progression of the endocardium over time, from its formation to the mature structure. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers.
3158	endothelium development	P	The process whose specific outcome is the progression of an endothelium over time, from its formation to the mature structure. Endothelium refers to the layer of cells lining blood vessels, lymphatics, the heart, and serous cavities, and is derived from bone marrow or mesoderm. Corneal endothelium is a special case, derived from neural crest cells.
3159	morphogenesis of an endothelium	P	The process in which the anatomical structure of an endothelium is generated and organized. Endothelium refers to the layer of cells lining blood vessels, lymphatics, the heart, and serous cavities, and is derived from bone marrow or mesoderm. Corneal endothelium is a special case, derived from neural crest cells.
3160	endocardium morphogenesis	P	The process in which the anatomical structure of the endocardium is generated and organized. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers.
3161	cardiac conduction system development	P	The process whose specific outcome is the progression of the cardiac conduction system over time, from its formation to the mature structure. The cardiac conduction system consists of specialized cardiomyocytes that regulate the frequency of heart beat.
3162	atrioventricular node development	P	The process whose specific outcome is the progression of the atrioventricular (AV) node over time, from its formation to the mature structure. The AV node is part of the cardiac conduction system that controls the timing of ventricle contraction by receiving electrical signals from the sinoatrial (SA) node and relaying them to the His-Purkinje system.
3163	sinoatrial node development	P	The process whose specific outcome is the progression of the sinoatrial (SA) node over time, from its formation to the mature structure. The SA node is part of the cardiac conduction system that controls the timing of heart muscle contraction. It relays electrical signals to the AV node.
3164	His-Purkinje system development	P	The process whose specific outcome is the progression of the His-Purkinje system over time, from its formation to the mature structure. The His-Purkinje system receives signals from the AV node and is composed of the fibers that regulate cardiac muscle contraction in the ventricles.
3165	Purkinje myocyte development	P	The process whose specific outcome is the progression of a Purkinje myocyte over time, from its formation to the mature structure. The Purkinje myocyte (also known as cardiac Purkinje fiber) is part of the cardiac conduction system that receives signals from the bundle of His and innervates the ventricular cardiac muscle.
3166	bundle of His development	P	The process whose specific outcome is the progression of the bundle of His over time, from its formation to the mature structure. The bundle of His is part of the His-Purkinje system that transmits signals from the AV node to the cardiac Purkinje fibers.
3167	atrioventricular bundle cell differentiation	P	The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cell of the atrioventricular bundle. These cells are specialized cardiomyocytes that transmit signals from the AV node to the cardiac Purkinje fibers.
3168	Purkinje myocyte differentiation	P	The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a Purkinje myocyte (also known as cardiac Purkinje fiber cell). These cells are specialized cardiomyocytes that receive signals from the bundle of His and innervate the ventricular cardiac muscle.
3169	coronary vein morphogenesis	P	The process in which the anatomical structures of veins of the heart are generated and organized.
3170	heart valve development	P	The progression of a heart valve over time, from its formation to the mature structure. A heart valve is a structure that restricts the flow of blood to different regions of the heart and forms from an endocardial cushion.
3171	atrioventricular valve development	P	The progression of the atrioventricular valve over time, from its formation to the mature structure.
3172	sinoatrial valve development	P	The progression of the sinoatrial valve over time, from its formation to the mature structure.
3173	ventriculo bulbo valve development	P	The progression of the ventriculo bulbo valve over time, from its formation to the mature structure.
3174	mitral valve development	P	The progression of the mitral valve over time, from its formation to the mature structure.
3175	tricuspid valve development	P	The progression of the tricuspid valve over time, from its formation to the mature structure.
3176	aortic valve development	P	The progression of the aortic valve over time, from its formation to the mature structure.
3177	pulmonary valve development	P	The progression of the pulmonary valve over time, from its formation to the mature structure.
3178	coronary sinus valve development	P	The progression of the valve of the coronary sinus over time, from its formation to the mature structure.
3179	heart valve morphogenesis	P	The process in which the structure of a heart valve is generated and organized.
3180	aortic valve morphogenesis	P	The process in which the structure of the aortic valve is generated and organized.
3181	atrioventricular valve morphogenesis	P	The process in which the structure of the atrioventricular valve is generated and organized.
3182	coronary sinus valve morphogenesis	P	The process in which the structure of the coronary sinus valve is generated and organized.
3183	mitral valve morphogenesis	P	The process in which the structure of the mitral valve is generated and organized.
3184	pulmonary valve morphogenesis	P	The process in which the structure of the pulmonary valve is generated and organized.
3185	sinoatrial valve morphogenesis	P	The process in which the structure of the sinoatrial valve is generated and organized.
3186	tricuspid valve morphogenesis	P	The process in which the structure of the tricuspid valve is generated and organized.
3187	ventriculo bulbo valve morphogenesis	P	The process in which the structure of the ventriculo bulbo valve is generated and organized.
3188	heart valve formation	P	The developmental process pertaining to the initial formation of a heart valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable.
3189	aortic valve formation	P	The developmental process pertaining to the initial formation of the aortic valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable.
3190	atrioventricular valve formation	P	The developmental process pertaining to the initial formation of the atrioventricular valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable.
3191	coronary sinus valve formation	P	The developmental process pertaining to the initial formation of the coronary sinus valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable.
3192	mitral valve formation	P	The developmental process pertaining to the initial formation of the mitral valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable.
3193	pulmonary valve formation	P	The developmental process pertaining to the initial formation of the pulmonary valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable.
3194	sinoatrial valve formation	P	The developmental process pertaining to the initial formation of the sinoatrial valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable.
3195	tricuspid valve formation	P	The developmental process pertaining to the initial formation of the tricuspid valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable.
3196	ventriculo bulbo valve formation	P	The developmental process pertaining to the initial formation of the ventriculo bulbo valve from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable.
3197	endocardial cushion development	P	The progression of a cardiac cushion over time, from its initial formation to the mature structure. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves.
3198	epithelial to mesenchymal transition involved in endocardial cushion formation	P	A transition where a cardiac epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell that will contribute to the formation of the endocardial cushion.
3199	endocardial cushion to mesenchymal transition involved in heart valve formation	P	A transition where an endocardial cushion cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell that will contribute to the formation of a cardiac valve.
3200	endocardial cushion to mesenchymal transition involved in heart chamber septation	P	A transition where an endocardial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell that will contribute to the formation of the heart septum.
3201	epithelial to mesenchymal transition involved in coronary vasculature morphogenesis	P	A transition where a cardiac epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell that will contribute to the shaping of the coronary vasculature.
3202	endocardial cushion to mesenchymal transition involved in cardiac skeleton development	P	A transition where an endocardial cushion cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell that will give rise to the cardiac skeleton.
3203	endocardial cushion morphogenesis	P	The process in which the anatomical structure of the endocardial cushion is generated and organized. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves.
3204	cardiac skeleton development	P	The progression of the cardiac skeleton over time, from its formation to the mature structure. The cardiac skeleton is a specialized extracellular matrix that separates the atria from the ventricles and provides physical support for the heart.
3205	cardiac chamber development	P	The progression of a cardiac chamber over time, from its formation to the mature structure. A cardiac chamber is an enclosed cavity within the heart.
3206	cardiac chamber morphogenesis	P	The process in which a cardiac chamber is generated and organized. A cardiac chamber is an enclosed cavity within the heart.
3207	cardiac chamber formation	P	The developmental process pertaining to the initial formation of a cardiac chamber from unspecified parts. A cardiac chamber is an enclosed cavity within the heart.
3208	cardiac ventricle morphogenesis	P	The process in which the cardiac ventricle is generated and organized. A cardiac ventricle receives blood from a cardiac atrium and pumps it out of the heart.
3209	cardiac atrium morphogenesis	P	The process in which the cardiac atrium is generated and organized. A cardiac atrium receives blood from a vein and pumps it to a cardiac ventricle.
3210	cardiac atrium formation	P	The developmental process pertaining to the initial formation of a cardiac atrium from unspecified parts. A cardiac atrium receives blood from a vein and pumps it to a cardiac ventricle.
3211	cardiac ventricle formation	P	The developmental process pertaining to the initial formation of a cardiac ventricle from unspecified parts. A cardiac ventricle receives blood from a cardiac atrium and pumps it out of the heart.
3212	cardiac left atrium morphogenesis	P	The process in which the left cardiac atrium is generated and organized.
3213	cardiac right atrium morphogenesis	P	The process in which the right cardiac atrium is generated and organized.
3214	cardiac left ventricle morphogenesis	P	The process in which the left cardiac ventricle is generated and organized.
3215	cardiac right ventricle morphogenesis	P	The process in which the right cardiac ventricle is generated and organized.
3216	cardiac left atrium formation	P	The developmental process pertaining to the initial formation of a left cardiac atrium from unspecified parts.
3217	cardiac right atrium formation	P	The developmental process pertaining to the initial formation of a cardiac right atrium from unspecified parts.
3218	cardiac left ventricle formation	P	The developmental process pertaining to the initial formation of a left cardiac ventricle from unspecified parts.
3219	cardiac right ventricle formation	P	The developmental process pertaining to the initial formation of a right cardiac ventricle from unspecified parts.
3220	left ventricular cardiac muscle tissue morphogenesis	P	The process in which the anatomical structures of left cardiac ventricle muscle are generated and organized.
3221	right ventricular cardiac muscle tissue morphogenesis	P	The process in which the anatomical structures of the right cardiac ventricle muscle are generated and organized.
3222	ventricular trabecula myocardium morphogenesis	P	The process in which the anatomical structures of the trabecular cardiac ventricle muscle are generated and organized.
3223	ventricular compact myocardium morphogenesis	P	The process in which the anatomical structures of the compact cardiac ventricle muscle are generated and organized.
3224	left ventricular compact myocardium morphogenesis	P	The process in which the anatomical structures of cardiac left ventricular compact myocardium are generated and organized.
3225	left ventricular trabecular myocardium morphogenesis	P	The process in which the anatomical structures of cardiac left ventricular trabecular myocardium are generated and organized.
3226	right ventricular compact myocardium morphogenesis	P	The process in which the anatomical structures of the right ventricular compact myocardium are generated and organized.
3227	right ventricular trabecular myocardium morphogenesis	P	The process in which the anatomical structures of the right ventricular myocardium are generated and organized.
3228	atrial cardiac muscle tissue development	P	The process whose specific outcome is the progression of cardiac muscle of the atrium over time, from its formation to the mature structure.
3229	ventricular cardiac muscle tissue development	P	The process whose specific outcome is the progression of ventricular cardiac muscle over time, from its formation to the mature structure.
3230	cardiac atrium development	P	The process whose specific outcome is the progression of a cardiac atrium over time, from its formation to the mature structure. A cardiac atrium receives blood from a vein and pumps it to a cardiac ventricle.
3231	cardiac ventricle development	P	The process whose specific outcome is the progression of a cardiac ventricle over time, from its formation to the mature structure. A cardiac ventricle receives blood from a cardiac atrium and pumps it out of the heart.
3232	bulbus arteriosus development	P	The process whose specific outcome is the progression of the bulbus arteriosus over time, from its formation to the mature structure. The bulbus arteriosus is an elastic heart chamber.
3233	bulbus arteriosus morphogenesis	P	The process in which the bulbus arteriosus is generated and organized. The bulbus arteriosus is an elastic cardiac chamber.
3234	bulbus arteriosus formation	P	The developmental process pertaining to the initial formation of the bulbus arteriosus from unspecified parts. The bulbus arteriosus is an elastic chamber of the heart.
3235	sinus venosus development	P	The progression of the sinus venosus over time, from its formation to the mature structure. The sinus venosus is a heart chamber attached to the atrium on the venous side of the embryonic heart.
3236	sinus venosus morphogenesis	P	The process in which the sinus venosus is generated and organized. The sinus venosus is a heart chamber attached to the atrium on the venous side of the embryonic heart.
3237	sinus venosus formation	P	The developmental process pertaining to the initial formation of the sinus venosus from unspecified parts. The sinus venosus is a heart chamber attached to the atrium on the venous side of the embryonic heart.
3238	conus arteriosus development	P	The progression of the conus arteriosus over time, from its formation to the mature structure. The conus arteriosus is a valved chamber with thick muscular walls stemming from the ventricle and connecting to the pulmonary trunk.
3239	conus arteriosus morphogenesis	P	The process in which the conus arteriosus is generated and organized. The conus arteriosus is a valved chamber with thick muscular walls stemming from the ventricle and connecting to the pulmonary trunk.
3240	conus arteriosus formation	P	The developmental process pertaining to the initial formation of the conus arteriosus from unspecified parts. The conus arteriosus is a valved chamber with thick muscular walls stemming from the ventricle and connecting to the pulmonary trunk.
3241	growth involved in heart morphogenesis	P	Developmental growth that contributes to the shaping of the heart.
3242	cardiac chamber ballooning	P	The morphogenic growth in which the chambers of the heart expand in size, contributing to their shaping.
3243	circumferential growth involved in left ventricle morphogenesis	P	The morphogenetic growth in which the left ventricle grows expanding its external boundary.
3244	radial growth involved in right ventricle morphogenesis	P	The morphogenic growth in which the right ventricle grows along a radial axis.
3245	cardiac muscle tissue growth involved in heart morphogenesis	P	The developmental growth of cardiac muscle tissue that contributes to the shaping of the heart.
3246	embryonic cardiac muscle cell growth involved in heart morphogenesis	P	The growth of a cardiac muscle cell during the embryonic period, that contributes to the shaping of the heart.
3247	post-embryonic cardiac muscle cell growth involved in heart morphogenesis	P	The growth of a cardiac muscle cell during the postembryonic period that contributes to the shaping of the heart.
3248	heart capillary growth	P	The increase in heart capillaries that accompanies physiological hypertrophy of cardiac muscle.
3249	cell proliferation involved in heart valve morphogenesis	P	The multiplication or reproduction of cells that contributes to the shaping of a heart valve.
3250	regulation of cell proliferation involved in heart valve morphogenesis	P	Any process that modulates the rate, frequency or extent of cell proliferation that contributes to the shaping of a heart valve.
3251	positive regulation of cell proliferation involved in heart valve morphogenesis	P	Any process that increases the rate, frequency or extent of cell proliferation that contributes to the shaping of a heart valve.
3252	negative regulation of cell proliferation involved in heart valve morphogenesis	P	Any process that decreases the rate, frequency or extent of cell proliferation that contributes to the shaping of a heart valve.
3253	cardiac neural crest cell migration involved in outflow tract morphogenesis	P	The orderly movement of a neural crest cell from one site to another that will contribute to the morphogenesis of the outflow tract.
3254	regulation of membrane depolarization	P	Any process that modulates the rate, frequency or extent of membrane depolarization. Membrane depolarization is the process in which membrane potential changes in the depolarizing direction from the resting potential, usually from negative to positive.
3255	endocardial precursor cell differentiation	P	The process in which a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of an endocardial precursor cell. A endocardial precursor cell is a cell that has been committed to a endocardial cell fate, but will undergo further cell divisions rather than terminally differentiate.
3256	regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation	P	Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that contributes to the differentiation of a myocardial precursor cell.
3257	positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation	P	Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter that contributes to the differentiation of a myocardial precursor cell.
3258	regulation of transcription from RNA polymerase II promoter involved in endocardial precursor cell differentiation	P	Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that contributes to the differentiation of an endocardial precursor cell.
3259	cardioblast anterior-lateral migration	P	The orderly movement of a cardioblast toward the head and laterally to form the heart field. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.
3260	cardioblast migration	P	The orderly movement of a cardiac progenitor cell to form the heart field. Cardiac progenitor cells are non-terminally differentiated, mesoderm-derived cells that are committed to differentiate into cells of the heart. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.
3261	cardiac muscle progenitor cell migration to the midline involved in heart field formation	P	The orderly movement of a myocardial progenitor cell toward the midline to form the heart field. Cardiac muscle progenitor cells are non-terminally differentiated, mesoderm-derived cells that are committed to differentiate into myocardial cells of the heart.
3262	endocardial progenitor cell migration to the midline involved in heart field formation	P	The orderly movement of an endocardial progenitor cell toward the midline to form the heart field. Cardiac muscle progenitor cells are non-terminally differentiated, mesoderm-derived cells that are committed to differentiate into endocardial cells of the heart.
3263	cardioblast proliferation	P	The multiplication or reproduction of cardioblasts, resulting in the expansion of the population in the heart field. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.
3264	regulation of cardioblast proliferation	P	Any process that modulates the frequency, rate or extent of cardioblast proliferation. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.
3265	regulation of primary heart field cardioblast proliferation	P	Any process that modulates the frequency, rate or extent of cardioblast proliferation in the primary heart field. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating. In mammals the primary heart field gives rise to the left ventricle.
3266	regulation of secondary heart field cardioblast proliferation	P	Any process that modulates the frequency, rate or extent of cardioblast proliferation in the second heart field. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating. The secondary heart field is the region of the heart that will form the majority of the mesodermal component of the right ventricle, the arterial pole (outflow tract) and the venous pole (inflow tract).
3267	canonical Wnt signaling pathway involved in positive regulation of secondary heart field cardioblast proliferation	P	A canonical Wnt signaling pathway that contributes to an increase in the frequency, or rate of cardioblast proliferation in the secondary heart field. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.
3268	fibroblast growth factor receptor signaling pathway involved in regulation of secondary heart field cardioblast proliferation	P	The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands contributing to the modulation of the frequency, rate or extent of cardioblast proliferation in the secondary heart field. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.
3269	BMP signaling pathway involved in regulation of secondary heart field cardioblast proliferation	P	A series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, which contributes to the modulation of the frequency, rate or extent of cardioblast proliferation in the secondary heart field. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.
3270	Notch signaling pathway involved in regulation of secondary heart field cardioblast proliferation	P	The series of molecular signals initiated by binding of an extracellular ligand to a Notch receptor on the surface of the target cell contributing to the modulation of the frequency, rate or extent of cardioblast proliferation in the secondary heart field. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.
3271	smoothened signaling pathway involved in regulation of secondary heart field cardioblast proliferation	P	The series of molecular signals generated as a consequence of activation of the transmembrane protein Smoothened contributing to the modulation of the frequency, rate or extent of cardioblast proliferation in the secondary heart field. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.
3272	endocardial cushion formation	P	The developmental process pertaining to the initial formation of an endocardial cushion. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves.
3273	cell migration involved in endocardial cushion formation	P	The orderly movement of a cell from one site to another that will contribute to the formation of an endocardial cushion. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves.
3274	endocardial cushion fusion	P	The cell-cell adhesion process of mesenchymal cardiac cushion cells that contributes to the process of cushion shaping.
3275	apoptotic process involved in outflow tract morphogenesis	P	Any apoptotic process that contributes to the shaping of the outflow tract. The outflow tract is the portion of the heart through which blood flows into the arteries.
3276	apoptotic process involved in heart valve morphogenesis	P	Any apoptotic process that contributes to the shaping of a heart valve.
3277	apoptotic process involved in endocardial cushion morphogenesis	P	Any apoptotic process that contributes to the shaping of an endocardial cushion. The endocardial cushion is a specialized region of mesenchymal cells that will give rise to the heart septa and valves.
3278	apoptotic process involved in heart morphogenesis	P	Any apoptotic process that contributes to the shaping of the heart.
3279	cardiac septum development	P	The progression of a cardiac septum over time, from its initial formation to the mature structure.
3281	ventricular septum development	P	The progression of the ventricular septum over time from its formation to the mature structure.
3282	ventricular septum intermedium development	P	The progression of the ventricular septum intermedium over time, from its formation to the mature structure.
3283	atrial septum development	P	The progression of the atrial septum over time, from its initial formation to the mature structure.
3284	septum primum development	P	The progression of the septum primum over time, from its formation to the mature structure.
3285	septum secundum development	P	The progression of the septum secundum over time, from its initial formation to the mature structure.
3286	atrial septum intermedium development	P	The progression of the atrial septum intermedium over time, from its formation to the mature structure.
3288	ventricular septum intermedium morphogenesis	P	The developmental process in which a ventricular septum intermedium is generated and organized.
3289	atrial septum primum morphogenesis	P	The process in which anatomical structure of an atrial septum primum is generated and organized.
3290	atrial septum secundum morphogenesis	P	The process in which anatomical structure of an atrial septum secundum is generated and organized.
3291	atrial septum intermedium morphogenesis	P	The process in which anatomical structure of an atrial septum intermedium is generated and organized.
3292	cardiac septum cell differentiation	P	The process in which an endocardial cushion cell becomes a cell of a cardiac septum.
3293	heart valve cell differentiation	P	The process in which an endocardial cushion cell give rise to a cell that is part of a heart valve.
3294	atrial ventricular junction remodeling	P	The reorganization or renovation of heart tissue that contributes to the maturation of the connection between an atrium and a ventricle.
3295	cell proliferation involved in atrial ventricular junction remodeling	P	The multiplication or reproduction of cells that contributes to the reorganization of tissue resulting in the maturation of the atrial ventricular junction.
3296	apoptotic process involved in atrial ventricular junction remodeling	P	Any apoptotic process that contributes to the reorganization of tissue resulting in the maturation of the atrial ventricular junction.
3297	heart wedging	P	The morphogenetic process in which the aorta inserts between the atrioventricular valves, contributing to the shaping of the heart.
3298	physiological muscle hypertrophy	P	The enlargement or overgrowth of all or part of a muscle organ or tissue due to an increase in the size of its muscle cells. Physiological hypertrophy is a normal process during development.
3299	muscle hypertrophy in response to stress	P	The enlargement or overgrowth of all or part of a muscle organ or tissue due to an increase in the size of its muscle cells as a result of a disturbance in organismal or cellular homeostasis.
3300	cardiac muscle hypertrophy	P	The enlargement or overgrowth of all or part of the heart muscle due to an increase in size of cardiac muscle cells without cell division.
3301	physiological cardiac muscle hypertrophy	P	The enlargement or overgrowth of all or part of the heart muscle due to an increase in size of cardiac muscle cells without cell division. This process contributes to the developmental growth of the heart.
3302	transforming growth factor beta receptor signaling pathway involved in heart jogging	P	A series of molecular signals initiated by the binding of an extracellular ligand to a transforming growth factor beta receptor on the surface of a target cell, which contributes to the process of heart jogging.
3303	BMP signaling pathway involved in heart jogging	P	A series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, which contributes to the process of heart jogging.
3304	myocardial epithelial involution involved in heart jogging	P	The morphogenetic process in which the myocardium bends along a linear axis and contributes to the process of heart jogging.
3305	cell migration involved in heart jogging	P	The orderly movement of a cell of the myocardium from one site to another that will contribute to heart jogging.
3306	Wnt signaling pathway involved in heart development	P	The series of molecular signals initiated by binding of Wnt protein to a receptor on the surface of the target cell, resulting a change in cell state that contributes to the progression of the heart over time.
3307	regulation of Wnt signaling pathway involved in heart development	P	Any process that modulates the rate, frequency, or extent of the series of molecular signals initiated by binding of Wnt protein to a frizzled family receptor on the surface of the target cell, resulting a change in cell state that contributes to the progression of the heart over time.
3308	negative regulation of Wnt signaling pathway involved in heart development	P	Any process that decreases the rate, frequency, or extent of the series of molecular signals initiated by binding of Wnt protein to a frizzled family receptor on the surface of the target cell, resulting a change in cell state that contributes to the progression of the heart over time.
3309	type B pancreatic cell differentiation	P	The process in which relatively unspecialized cells acquire specialized structural and/or functional features of a type B pancreatic cell. A type B pancreatic cell is a cell located towards center of the islets of Langerhans that secretes insulin.
3310	pancreatic A cell differentiation	P	The process in which relatively unspecialized cells acquire specialized structural and functional features of a pancreatic A cell. A pancreatic A cell is a cell in the pancreas that secretes glucagon.
3311	pancreatic D cell differentiation	P	The process in which relatively unspecialized cells acquire specialized structural and functional features that characterize a pancreatic delta cell. A delta cell is a cell of the pancreas that produces somatostatin.
3312	pancreatic PP cell differentiation	P	The process in which relatively unspecialized cells acquire specialized structural and functional features of a pancreatic polypeptide-producing cell. A pancreatic polypeptide-producing cell is a cell in the pancreas that produces pancreatic polypeptide.
3313	heart rudiment development	P	The progression of the heart rudiment over time, from its initial formation to the mature structure. The heart rudiment is a cone-like structure that is formed when myocardial progenitor cells of the heart field fuse at the midline. The heart rudiment is the first structure of the heart tube.
3314	heart rudiment morphogenesis	P	The process in which the anatomical structures of the heart rudiment are generated and organized.
3315	heart rudiment formation	P	The developmental process pertaining to the initial formation of the heart rudiment.
3316	establishment of myocardial progenitor cell apical/basal polarity	P	The specification and formation of the apicobasal polarity of an myocardial progenitor cell that contributes to the formation of the heart rudiment.
3317	cardioblast cell midline fusion	P	The attachment of cardiac progenitor cells to one another that contributes to the formation of the heart rudiment.
3318	cell migration to the midline involved in heart development	P	The orderly movement of a cell toward the midline that contributes to the progression of the heart over time.
3319	cardioblast migration to the midline involved in heart rudiment formation	P	The orderly movement of a cardioblast toward the midline that contributes to the initial appearance of the heart rudiment.
3320	heart rudiment involution	P	The inward folding of myocardial tissue derived from the right half of the heart rudiment that will form the future ventral part of the heart tube.
3321	positive regulation of blood pressure by epinephrine-norepinephrine	P	Any process in which the force of blood traveling through the circulatory system is increased by the chemicals epinephrine and norepinephrine.
3322	pancreatic A cell development	P	The process whose specific outcome is the progression of a pancreatic A cell over time, from its formation to the mature structure. A pancreatic A cell is a cell in the pancreas that secretes glucagon.
3323	type B pancreatic cell development	P	The process whose specific outcome is the progression of a type B pancreatic cell over time, from its formation to the mature structure. A type B pancreatic cell is a cell located towards center of the islets of Langerhans that secretes insulin.
3324	pancreatic D cell development	P	The process whose specific outcome is the progression of a pancreatic delta cell over time, from its formation to the mature structure. A delta cell is a cell of the pancreas that produces somatostatin.
3325	pancreatic PP cell development	P	The process whose specific outcome is the progression of a pancreatic PP cell over time, from its formation to the mature structure. A pancreatic polypeptide-producing cell is a cell in the pancreas that produces pancreatic polypeptide.
3326	pancreatic A cell fate commitment	P	The commitment of a cell to a pancreatic A cell and its capacity to differentiate into a pancreatic A cell. A pancreatic A cell is a cell in the pancreas that secretes glucagon.
3327	type B pancreatic cell fate commitment	P	The commitment of a cell to a type B pancreatic cell fate and its capacity to differentiate into a type B pancreatic cell. A type B pancreatic cell is a cell located towards center of the islets of Langerhans that secretes insulin.
3328	pancreatic D cell fate commitment	P	The commitment of a cell to a pancreatic D cell fate and its capacity to differentiate into a pancreatic D cell. A delta cell is a cell of the pancreas that produces somatostatin.
3329	pancreatic PP cell fate commitment	P	The commitment of a cell to a pancreatic PP cell fate and its capacity to differentiate into a pancreatic PP cell. A pancreatic polypeptide-producing cell is a cell in the pancreas that produces pancreatic polypeptide.
3330	regulation of extracellular matrix constituent secretion	P	Any process that modulates the rate, frequency, or extent of the controlled release of molecules that form the extracellular matrix, including carbohydrates and glycoproteins by a cell or a group of cells.
3331	positive regulation of extracellular matrix constituent secretion	P	Any process that increases the rate, frequency, or extent of the controlled release of molecules that form the extracellular matrix, including carbohydrates and glycoproteins by a cell or a group of cells.
3332	negative regulation of extracellular matrix constituent secretion	P	Any process that decreases the rate, frequency, or extent the controlled release of molecules that form the extracellular matrix, including carbohydrates and glycoproteins by a cell or a group of cells.
3333	amino acid transmembrane transport	P	The directed movement of amino acids, organic acids containing one or more amino substituents across a membrane by means of some agent such as a transporter or pore.
3334	keratinocyte development	P	The process whose specific outcome is the progression of a keratinocyte over time, from its formation to the mature structure.
3335	corneocyte development	P	The process whose specific outcome is the progression of the corneocyte over time, from its formation to the mature structure. A corneocyte is the last stage of development of a keratinocyte where the keratinocyte flattens, loses its nucleus and eventually delaminates from the epidermis.
3336	corneocyte desquamation	P	The delamination process that results in the shedding of a corneocyte from the surface of the epidermis.
3337	mesenchymal to epithelial transition involved in metanephros morphogenesis	P	A transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the metanephros.
3338	metanephros morphogenesis	P	The process in which the anatomical structures of the metanephros are generated and organized.
3339	regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis	P	Any process that modulates the rate, frequency or extent of the transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the metanephros.
3340	negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis	P	Any process that decreases the rate, frequency or extent of the transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the metanephros.
3341	cilium movement	P	The directed, self-propelled movement of a cilium.
3342	proepicardium development	P	The progression of the proepicardium from its formation to the mature structure. The proepicardium is an outpouching of the septum transversum.
3343	septum transversum development	P	The progression of the septum transversum from its initial formation to the mature structure. The septum transversum is a portion of the trunk mesenchyme.
3344	pericardium morphogenesis	P	The process in which the anatomical structure of the pericardium is generated and organized.
3345	proepicardium cell migration involved in pericardium morphogenesis	P	The coordinated movement of a mesenchymal proepicardial cell to the surface of the developing heart.
3346	epicardium-derived cell migration to the myocardium	P	The orderly movement of a cell that have undergone an epithelial to mesenchymal transition from the epicardium into the myocardium.
3347	epicardial cell to mesenchymal cell transition	P	A transition where an epicardial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell. The epicardium is a part of the pericardium.
3348	cardiac endothelial cell differentiation	P	The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cardiac endothelial cell.
3349	epicardium-derived cardiac endothelial cell differentiation	P	The process in which an epicardial cell acquires the specialized structural and/or functional features of a cardiac endothelial cell.
3350	pulmonary myocardium development	P	The progression of the pulmonary myocardium over time, from its initial formation to the mature structure. The pulmonary myocardium is the myocardial tissue present in the pulmonary vein.
3351	epithelial cilium movement	P	The directed, self-propelled movement of a cilium of an epithelial cell. This movement is usually coordinated between many epithelial cells, and serves to move fluid.
3352	regulation of cilium movement	P	Any process that modulates the rate, frequency, or extent of cilium movement, the directed, self-propelled movement of a cilium.
3353	positive regulation of cilium movement	P	Any process that increases the rate, frequency, or extent of cilium movement, the directed, self-propelled movement of a cilium.
3354	negative regulation of cilium movement	P	Any process that decreases the rate, frequency, or extent of cilium movement, the directed, self-propelled movement of a cilium.
3355	cilium movement involved in otolith formation	P	The directed, self-propelled movement of a cilium of an inner ear epithelial cell, resulting the aggregation of otolith seed particles.
3356	regulation of cilium beat frequency	P	Any process that modulates the frequency of cilium movement, the directed, self-propelled movement of a cilium.
3357	noradrenergic neuron differentiation	P	The process in which a relatively unspecialized cell acquires specialized features of an noradrenergic neuron, a neuron that secretes noradrenaline.
3358	noradrenergic neuron development	P	The process whose specific outcome is the progression of a noradrenergic neuron over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.
3359	noradrenergic neuron fate commitment	P	The process in which the developmental fate of a cell becomes restricted such that it will develop into a noradrenergic neuron.
3360	brainstem development	P	The progression of the brainstem from its formation to the mature structure. The brainstem is the part of the brain that connects the brain with the spinal cord.
3361	noradrenergic neuron differentiation involved in brainstem development	P	The process in which a relatively unspecialized cell acquires specialized features of an noradrenergic neuron that is part of the brainstem.
3362	noradrenergic neuron fate commitment involved in brainstem development	P	The process in which the developmental fate of a cell becomes restricted such that it will develop into a noradrenergic neuron that is part of the brainstem.
3363	lamellipodium assembly involved in ameboidal cell migration	P	Formation of a lamellipodium, a thin sheetlike extension of the surface of a migrating cell that contributes to the directed self propelled movement of a cell.
3364	lamellipodium assembly involved in mesendodermal cell migration	P	Formation of a lamellipodium, a thin sheetlike extension of the surface of a migrating cell that contributes to the directed self-propelled movement of a mesendodermal cell.
3365	establishment of cell polarity involved in ameboidal cell migration	P	The specification and formation of anisotropic intracellular organization that contributes to the self-propelled directed movement of an ameboid cell.
3366	cell-matrix adhesion involved in ameboidal cell migration	P	The binding of a cell to the extracellular matrix that contributes to the directed movement of an ameboid cell.
3367	cell-cell adhesion involved in ameboidal cell migration	P	The attachment of one ameboid cell to another that contributes to the establishment of cell polarity that is part of the directed movement of one of the cells.
3368	cell-matrix adhesion involved in mesendodermal cell migration	P	The binding of a cell to the extracellular matrix that contributes to the directed movement of a mesendodermal cell.
3369	establishment of cell polarity involved in mesendodermal cell migration	P	The specification and formation of anisotropic intracellular organization that contributes to the self-propelled directed movement of a mesendodermal cell.
3370	cell-cell adhesion involved in mesendodermal cell migration	P	The attachment of mesendodermal cells to each other that contributes to the establishment of cell polarity that is part of the directed movement of the cells of the mesendoderm.
3371	establishment or maintenance of cytoskeleton polarity involved in ameboidal cell migration	P	Any cellular process that results in the specification, formation or maintenance of polarized cytoskeletal structures that contribute to the cell polarity of a migrating ameboid cell.
3372	establishment or maintenance of cytoskeleton polarity involved in mesendodermal cell migration	P	Any cellular process that results in the specification, formation or maintenance of polarized cytoskeletal structures that contribute to the cell polarity of a migrating mesendodermal cell.
3373	dynamin family protein polymerization involved in membrane fission	P	The process of creating dynamin family protein polymers, compounds composed of a large number of dynamin family protein monomers. Dynamin family protein polymers form around lipid tubes and contribute to membrane fission.
3374	dynamin family protein polymerization involved in mitochondrial fission	P	The process of creating dynamin protein family polymers, compounds composed of a large number of dynamin family monomers around a lipid tube of a dividing mitochondrion. Dynamin polymers form around lipid tubes and contribute to membrane fission.
3375	regulation of dynamin family protein polymerization involved in membrane fission	P	Any process that modulates the rate, frequency, or extent of dynamin family protein polymerization involved in mitochondrial fission.
3376	sphingosine-1-phosphate signaling pathway	P	A series of molecular signals initiated by the sphingolipid sphingosine-1-phosphate (S1P) binding to a receptor on the surface of the cell, and which proceeds with the activated receptor transmitting the signal by promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The pathway ends with regulation of a downstream cellular process, e.g. transcription.
3377	regulation of apoptosis by sphingosine-1-phosphate signaling pathway	P	A sphingosine-1-phosphate signaling pathway that modulates the rate, frequency, or extent of apoptosis.
3378	regulation of inflammatory response by sphingosine-1-phosphate signaling pathway	P	A sphingosine-1-phosphate signaling pathway that modulates the rate, frequency, or extent of the inflammatory response.
3379	establishment of cell polarity involved in gastrulation cell migration	P	The specification and formation of anisotropic intracellular organization that contributes to the self-propelled directed movement of an ameboid cell taking part in gastrulation.
3380	establishment or maintenance of cytoskeleton polarity involved in gastrulation	P	Any cellular process that results in the specification, formation or maintenance of polarized cytoskeletal structures that contribute to the cell polarity of a migrating ameboid cell taking part in gastrulation.
3381	epithelial cell morphogenesis involved in gastrulation	P	The change in form that occurs when an epithelial cell progresses from it initial formation to its mature state, contributing to the process of gastrulation.
3382	epithelial cell morphogenesis	P	The change in form that occurs when an epithelial cell progresses from its initial formation to its mature state.
3383	apical constriction	P	The actin-mediated process that results in the contraction of the apical end of a polarized columnar epithelial cell.
3384	apical constriction involved in gastrulation	P	The actin-mediated process that results in the contraction of the apical end of a polarized columnar epithelial cell, contributing to the process of gastrulation.
3385	cell-cell signaling involved in amphid sensory organ development	P	Any process that mediates the transfer of information from one cell to another and contributes to the progression of an amphid sensory organ over time, from its formation to the mature state.
3386	amphid sensory organ development	P	The progression of the amphid sensory organ over time, from its formation to the mature structure. Amphid sensory organs are the sensory organs of nematodes.
3387	neuron differentiation involved in amphid sensory organ development	P	The process in which a relatively unspecialized cell acquires specialized features of a neuron that contributes to the progression of the amphid sensory gland.
3388	neuron development involved in amphid sensory organ development	P	The process whose specific outcome is the progression of a neuron over time, that contributes to the development of the amphid sensory organ.
3389	retrograde extension	P	The progression of a neuronal projection over time by the attachment of a part of the cell to an anchor and the subsequent migration of the cell body away from the anchor point.
3390	dendrite development by retrograde extension	P	The progression of a dendrite over time by the attachment of a part of the neuron to an anchor and the subsequent migration of the cell body away from the anchor point.
3391	amphid sensory organ dendrite retrograde extension	P	The progression of an amphid sensory organ's neuronal dendrite over time by the attachment of a part of the cell to an anchor and the subsequent migration of the cell body away from the anchor point.
3392	cell adhesion involved in retrograde extension	P	The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix that contributes to the process of retrograde extension.
3393	neuron migration involved in retrograde extension	P	The directed, self-propelled movement of a neuron that contributes to the process of retrograde extension.
3394	cell adhesion involved in dendrite retrograde extension	P	The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix that contributes to the process of retrograde extension of a dendrite.
3395	neuron migration involved in dendrite retrograde extension	P	The directed, self-propelled movement of a neuron that contributes to the process of retrograde extension of a dendrite.
3396	cell adhesion involved in amphid sensory organ dendrite retrograde extension	P	The directed, self-propelled movement of a neuron that contributes to the process of retrograde extension of a dendrite in a neuron of the amphid sensory organ.
3397	neuron migration involved in amphid sensory organ dendrite retrograde extension	P	The directed, self-propelled movement of a neuron that contributes to the process of retrograde extension of a dendrite of a neuron in the amphid sensory organ.
3398	glial cell differentiation involved in amphid sensory organ development	P	The process in which a relatively unspecialized cell acquires the specialized features of a glial cell of the amphid sensory organ.
3399	cytoneme morphogenesis	P	The process in which the anatomical structures of a cytoneme are shaped. A cytoneme is a long, thin and polarized actin-based cytoplasmic extension that projects from a cell.
3400	regulation of COPII vesicle coating	P	Any process that modulates the rate, frequency, or extent of the addition of COPII proteins and adaptor proteins to ER membranes during the formation of transport vesicles, forming a vesicle coat.
3401	axis elongation	P	The developmental growth that results in the elongation of a line that defines polarity or symmetry in an anatomical structure.
3402	planar cell polarity pathway involved in axis elongation	P	The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal to modulate cytoskeletal elements and control cell polarity that contributes to axis elongation.
3403	optic vesicle formation	P	The developmental process pertaining to the initial formation of the optic vesicle from the lateral wall of the forebrain. This process begins with the specific processes that contribute to the appearance of the vesicle and ends when the vesicle has evaginated. The optic vesicle is the evagination of neurectoderm that precedes formation of the optic cup.
3404	optic vesicle morphogenesis	P	The developmental process pertaining to the formation and shaping of the optic vesicle. This process begins with the specific processes that contribute to the appearance of the vesicle and ends when the vesicle has evaginated. The optic vesicle is the evagination of neurectoderm that precedes formation of the optic cup.
3405	optic vesicle elongation	P	The developmental growth that results in the lengthening of the optic vesicle in the posterior direction.
3406	retinal pigment epithelium development	P	The progression of the retinal pigment epithelium over time, from its initial formation to the mature structure. The retinal pigment epithelium is the melanin-containing layer of cells between the retina and the choroid that absorbs scattered and reflected light and removes waste products produced by the photoreceptor cells.
3407	neural retina development	P	The progression of the neural retina over time from its initial formation to the mature structure. The neural retina is the part of the retina that contains neurons and photoreceptor cells.
3408	optic cup formation involved in camera-type eye development	P	The developmental process pertaining to the initial formation of the optic cup, a two-walled vesicle formed from the optic vesicle.
3409	optic cup structural organization	P	The process that contributes to creating the structural organization of the optic cup. This process pertains to the physical shaping of the rudimentary structure.
3410	anterior rotation of the optic cup	P	A 90 degree-rotation of the optic cup resulting in its alignment with the anterior-posterior body axis.
3411	cell motility involved in camera-type eye morphogenesis	P	Any process involved in the controlled self-propelled movement of a cell that results in translocation of the cell from one place to another and contributes to the physical shaping or formation of the camera-type eye.
3412	establishment of epithelial cell apical/basal polarity involved in camera-type eye morphogenesis	P	The specification and formation of the apicobasal polarity of an epithelial cell that contributes to the shaping of a camera-type eye.
3413	chondrocyte differentiation involved in endochondral bone morphogenesis	P	The process in which a chondroblast acquires specialized structural and/or functional features of a chondrocyte that will contribute to the development of a bone. A chondrocyte is a polymorphic cell that forms cartilage.
3414	chondrocyte morphogenesis involved in endochondral bone morphogenesis	P	The process in which the structures of a chondrocyte that will contribute to bone development are generated and organized.
3415	chondrocyte hypertrophy	P	The growth of a chondrocyte, where growth contributes to the progression of the chondrocyte over time.
3416	endochondral bone growth	P	The increase in size or mass of an endochondral bone that contributes to the shaping of the bone.
3417	growth plate cartilage development	P	The process whose specific outcome is the progression of the cartilage that will provide a scaffold for mineralization of endochondral bones as they elongate or grow.
3418	growth plate cartilage chondrocyte differentiation	P	The process in which a chondroblast acquires specialized structural and/or functional features of a chondrocyte that will contribute to the growth of a bone. A chondrocyte is a polymorphic cell that forms cartilage.
3419	growth plate cartilage chondrocyte proliferation	P	The multiplication or reproduction of chondrocytes in a growing endochondral bone, resulting in the expansion of a cell population.
3420	regulation of growth plate cartilage chondrocyte proliferation	P	Any process that modulates the rate, frequency, or extent of the multiplication or reproduction of chondrocytes in a growing endochondral bone, resulting in the expansion of a cell population.
3421	growth plate cartilage axis specification	P	The establishment, maintenance and elaboration of the columnar cartilage along the axis of a long bone that contributes to bone growth.
3422	growth plate cartilage morphogenesis	P	The process in which the anatomical structures of growth plate cartilage are generated and organized.
3423	growth plate cartilage chondrocyte division	P	The process resulting in the oriented physical partitioning and separation of a chondrocytes in the growth plate.
3424	establishment of cell polarity involved in growth plate cartilage chondrocyte division	P	The cellular process that results in the specification, formation or maintenance of anisotropic intracellular organization that results in the directional division of a growth plate cartilage chondrocyte.
3425	establishment of mitotic spindle orientation involved in growth plate cartilage chondrocyte division	P	A cell cycle process that sets the alignment of mitotic spindle relative to other cellular structures and contributes to oriented chondrocyte division in the growth plate.
3426	cytoskeleton polarization involved in growth plate cartilage chondrocyte division	P	A process that is carried out at the cellular level which results in the polarization of cytoskeletal structures in a growth plate cartilage chondrocyte. This process results in the oriented division of the cell.
3427	regulation of cytoskeleton polarization involved in growth plate cartilage chondrocyte division	P	The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell that modulates the rate, frequency, or extent of the polarization of cytoskeletal structures in a growth plate cartilage chondrocyte. This process results in the oriented division of the cell.
3428	chondrocyte intercalation involved in growth plate cartilage morphogenesis	P	The orderly movement of a chondrocyte from one site to another that contributes to the shaping of growth plate cartilage in an endochondral bone.
3429	growth plate cartilage chondrocyte morphogenesis	P	The process in which the structures of a chondrocyte in the growth plate cartilage are generated and organized.
3430	growth plate cartilage chondrocyte growth	P	The growth of a growth plate cartilage chondrocyte, where growth contributes to the progression of the chondrocyte over time from one condition to another.
3431	growth plate cartilage chondrocyte development	P	The progression of a growth plate cartilage chondrocyte over time from after its fate commitment to the mature cell.
3432	cell growth involved in growth plate cartilage chondrocyte morphogenesis	P	The growth of a growth plate cartilage chondrocyte, where growth contributes to the shaping of the chondrocyte over time.
3433	chondrocyte development involved in endochondral bone morphogenesis	P	The progression of a chondrocyte over time from after its commitment to its mature state where the chondrocyte will contribute to the shaping of an endochondral bone.
3434	BMP signaling pathway involved in growth plate cartilage chondrocyte development	P	A series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, which contributes to the progression of a growth plate cartilage chondrocyte over time.
3435	smoothened signaling pathway involved in growth plate cartilage chondrocyte development	P	The series of molecular signals generated as a consequence of activation of the transmembrane protein Smoothened that contributes to the progression of a growth plate cartilage chondrocyte over time.
3436	regulation of cell adhesion involved in growth plate cartilage morphogenesis	P	Any process that modulates the frequency, rate or extent of attachment of a cell to another cell or to the extracellular matrix and contributes to the shaping of the growth plate cartilage of an endochondral bone.
3437	regulation of cell communication involved in growth plate cartilage morphogenesis	P	Any process that modulates the frequency, rate or extent of cell communication that contributes to the shaping of the growth plate cartilage.
3674	molecular_function	F	Elemental activities, such as catalysis or binding, describing the actions of a gene product at the molecular level. A given gene product may exhibit one or more molecular functions.
3676	nucleic acid binding	F	Interacting selectively and non-covalently with any nucleic acid.
3677	DNA binding	F	Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
3678	DNA helicase activity	F	Catalysis of the reaction: NTP + H2O = NDP + phosphate, to drive the unwinding of a DNA helix.
3680	AT DNA binding	F	Interacting selectively and non-covalently with oligo(A) and oligo(T) tracts of DNA (AT DNA).
3681	bent DNA binding	F	Interacting selectively and non-covalently with DNA in a bent conformation.
3682	chromatin binding	F	Interacting selectively and non-covalently with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase.
3684	damaged DNA binding	F	Interacting selectively and non-covalently with damaged DNA.
3688	DNA replication origin binding	F	Interacting selectively and non-covalently with the DNA replication origin, a unique DNA sequence of a replicon at which DNA replication is initiated and proceeds bidirectionally or unidirectionally.
3689	DNA clamp loader activity	F	Catalysis of the reaction: ATP + H2O = ADP + phosphate, to drive the opening of the ring structure of the PCNA complex, or any of the related sliding clamp complexes, and their closing around the DNA duplex.
3690	double-stranded DNA binding	F	Interacting selectively and non-covalently with double-stranded DNA.
3691	double-stranded telomeric DNA binding	F	Interacting selectively and non-covalently with double-stranded telomere-associated DNA.
3692	left-handed Z-DNA binding	F	Interacting selectively and non-covalently with DNA in the Z form, i.e. a left-handed helix in which the phosphate backbone zigzags.
3693	P-element binding	F	Interacting selectively and non-covalently with any P-element, a class of Drosophila transposon responsible for hybrid dysgenesis.
3695	random coil DNA binding	F	Interacting selectively and non-covalently with DNA in a random coil configuration.
3696	satellite DNA binding	F	Interacting selectively and non-covalently with satellite DNA, the many tandem repeats (identical or related) of a short basic repeating unit; many have a base composition or other property different from the genome average that allows them to be separated from the bulk (main band) genomic DNA.
3697	single-stranded DNA binding	F	Interacting selectively and non-covalently with single-stranded DNA.
3700	transcription factor activity, sequence-specific DNA binding	F	Interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription. The transcription factor may or may not also interact selectively with a protein or macromolecular complex.
3705	transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding	F	Interacting selectively and non-covalently with a sequence of DNA that is in a distal enhancer region for RNA polymerase II (RNAP II) in order to modulate transcription by RNAP II.
3707	steroid hormone receptor activity	F	Combining with a steroid hormone and transmitting the signal within the cell to initiate a change in cell activity or function.
3708	retinoic acid receptor activity	F	Combining with retinoic acid and transmitting the signal to the transcriptional machinery by interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription by RNA polymerase II. Retinoic acid is one of the forms of vitamin A.
3712	transcription cofactor activity	F	Interacting selectively and non-covalently with a regulatory transcription factor and also with the basal transcription machinery in order to modulate transcription. Cofactors generally do not bind the template nucleic acid, but rather mediate protein-protein interactions between regulatory transcription factors and the basal transcription machinery.
3713	transcription coactivator activity	F	Interacting selectively and non-covalently with a activating transcription factor and also with the basal transcription machinery in order to increase the frequency, rate or extent of transcription. Cofactors generally do not bind the template nucleic acid, but rather mediate protein-protein interactions between activating transcription factors and the basal transcription machinery.
3714	transcription corepressor activity	F	Interacting selectively and non-covalently with a repressing transcription factor and also with the basal transcription machinery in order to stop, prevent, or reduce the frequency, rate or extent of transcription. Cofactors generally do not bind the template nucleic acid, but rather mediate protein-protein interactions between repressive transcription factors and the basal transcription machinery.
3720	telomerase activity	F	Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). Catalyzes extension of the 3'- end of a DNA strand by one deoxynucleotide at a time using an internal RNA template that encodes the telomeric repeat sequence.
3721	telomerase RNA reverse transcriptase activity	F	Catalysis of the extension of the 3' end of a DNA strand by one deoxynucleotide at a time. Cannot initiate a chain de novo; uses the RNA subunit of the telomerase enzyme complex as its template.
3723	RNA binding	F	Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
3724	RNA helicase activity	F	Catalysis of the reaction: NTP + H2O = NDP + phosphate, to drive the unwinding of a RNA helix.
3725	double-stranded RNA binding	F	Interacting selectively and non-covalently with double-stranded RNA.
3726	double-stranded RNA adenosine deaminase activity	F	Catalysis of the reaction: adenosine + H2O = inosine + NH3, in a double-stranded RNA molecule.
3727	single-stranded RNA binding	F	Interacting selectively and non-covalently with single-stranded RNA.
3729	mRNA binding	F	Interacting selectively and non-covalently with messenger RNA (mRNA), an intermediate molecule between DNA and protein. mRNA includes UTR and coding sequences, but does not contain introns.
3730	mRNA 3'-UTR binding	F	Interacting selectively and non-covalently with the 3' untranslated region of an mRNA molecule.
3735	structural constituent of ribosome	F	The action of a molecule that contributes to the structural integrity of the ribosome.
3743	translation initiation factor activity	F	Functions in the initiation of ribosome-mediated translation of mRNA into a polypeptide.
3746	translation elongation factor activity	F	Functions in chain elongation during polypeptide synthesis at the ribosome.
3747	translation release factor activity	F	Involved in catalyzing the release of a nascent polypeptide chain from a ribosome.
3755	peptidyl-prolyl cis-trans isomerase activity	F	Catalysis of the reaction: peptidyl-proline (omega=180) = peptidyl-proline (omega=0).
3756	protein disulfide isomerase activity	F	Catalysis of the rearrangement of both intrachain and interchain disulfide bonds in proteins.
3774	motor activity	F	Catalysis of the generation of force resulting either in movement along a microfilament or microtubule, or in torque resulting in membrane scission, coupled to the hydrolysis of a nucleoside triphosphate.
3777	microtubule motor activity	F	Catalysis of movement along a microtubule, coupled to the hydrolysis of a nucleoside triphosphate (usually ATP).
3779	actin binding	F	Interacting selectively and non-covalently with monomeric or multimeric forms of actin, including actin filaments.
3785	actin monomer binding	F	Interacting selectively and non-covalently with monomeric actin, also known as G-actin.
3786	actin lateral binding	F	Interacting selectively and non-covalently with an actin filament along its length.
3796	lysozyme activity	F	Catalysis of the hydrolysis of the beta-(1->4) linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan.
3810	protein-glutamine gamma-glutamyltransferase activity	F	Catalysis of the reaction: protein glutamine + alkylamine = protein N5-alkylglutamine + NH3. This reaction is the formation of the N6-(L-isoglutamyl)-L-lysine isopeptide, resulting in cross-linking polypeptide chains; the gamma-carboxamide groups of peptidyl-glutamine residues act as acyl donors, and the 6-amino-groups of peptidyl-lysine residues act as acceptors, to give intra- and intermolecular N6-(5-glutamyl)lysine cross-links.
3823	antigen binding	F	Interacting selectively and non-covalently with an antigen, any substance which is capable of inducing a specific immune response and of reacting with the products of that response, the specific antibody or specifically sensitized T-lymphocytes, or both. Binding may counteract the biological activity of the antigen.
3824	catalytic activity	F	Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific binding sites for substrates, and are usually composed wholly or largely of protein, but RNA that has catalytic activity (ribozyme) is often also regarded as enzymatic.
3825	alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity	F	Catalysis of the reaction: UDP-glucose + D-glucose-6-phosphate = UDP + alpha,alpha-trehalose-6-phosphate.
3826	alpha-ketoacid dehydrogenase activity	F	Catalysis of an oxidation-reduction (redox) reaction involving an alpha-ketoacid.
3827	alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity	F	Catalysis of the reaction: 3-(alpha-D-mannosyl)-beta-D-mannosyl-R + UDP-N-acetyl-alpha-D-glucosamine = 3-(2-[N-acetyl-beta-D-glucosaminyl]-alpha-D-mannosyl)-beta-D-mannosyl-R + H(+) + UDP.
3828	alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity	F	Catalysis of the reaction: CMP-N-acetylneuraminate + alpha-N-acetylneuraminyl-(2->3)-beta-D-galactosyl-R = CMP + alpha-N-acetylneuraminyl-(2->8)-alpha-N-acetylneuraminyl-(2->3)-beta-D-galactosyl-R.
3829	beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity	F	Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + beta-D-galactosyl-(1->3)-N-acetyl-D-galactosaminyl-R = UDP + beta-D-galactosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->6)]-N-acetyl-D-galactosaminyl-R.
3830	beta-1,4-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity	F	Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + beta-D-mannosyl-R = UDP + 4-(N-acetyl-beta-D-glucosaminyl)-beta-D-mannosyl-R.
3831	beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity	F	Catalysis of the reaction: UDP-galactose + N-acetyl-beta-D-glucosaminylglycopeptide = UDP + beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosaminylglycopeptide.
3832	beta-alanyl-dopamine hydrolase activity	F	Catalysis of the reaction: N-beta-alanyl dopamine + H2O = dopamine + beta-alanine.
3833	beta-alanyl-dopamine synthase activity	F	Catalysis of the synthesis of beta-alanyl-dopamine from the precursor dopamine (3,4-dihydroxyphenylethylamine).
3834	beta-carotene 15,15'-monooxygenase activity	F	Catalysis of the reaction: beta-carotene + O(2) = 2 retinal.
3835	beta-galactoside alpha-2,6-sialyltransferase activity	F	Catalysis of the reaction: CMP-N-acetylneuraminate + beta-D-galactosyl-(1->4)-acetyl-beta-D-glucosamine = CMP + alpha-N-acetylneuraminyl-(2->6)-beta-D-galactosyl-(1->4)-N-acetyl-beta-D-glucosamine.
3836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity	F	Catalysis of the reaction: CMP-N-acetylneuraminate + beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl-R = CMP + alpha-N-acetylneuraminyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-alpha-D-galactosaminyl-R.
3837	beta-ureidopropionase activity	F	Catalysis of the reaction: N-carbamoyl-beta-alanine + H2O = beta-alanine + CO2 + NH3.
3838	sterol 24-C-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + 5-alpha-cholest-8,24-dien-3-beta-ol = S-adenosyl-L-homocysteine + 24-methylene-5-alpha-cholest-8-en-3-beta-ol.
3839	gamma-glutamylcyclotransferase activity	F	Catalysis of the reaction: (5-L-glutamyl)-L-amino acid = 5-oxoproline + L-amino acid.
3840	gamma-glutamyltransferase activity	F	Catalysis of the reaction: (5-L-glutamyl)-peptide + an amino acid = peptide + 5-L-glutamyl-amino acid.
3841	1-acylglycerol-3-phosphate O-acyltransferase activity	F	Catalysis of the reaction: acyl-CoA + 1-acyl-sn-glycerol-3-phosphate = CoA + 1,2-diacyl-sn-glycerol-3-phosphate.
3842	1-pyrroline-5-carboxylate dehydrogenase activity	F	Catalysis of the reaction: 1-pyrroline-5-carboxylate + NAD+ + H2O = L-glutamate + NADH + H(+).
3843	1,3-beta-D-glucan synthase activity	F	Catalysis of the reaction: UDP-glucose + [(1->3)-beta-D-glucosyl](n) = UDP + [(1->3)-beta-D-glucosyl](n+1).
3844	1,4-alpha-glucan branching enzyme activity	F	Catalysis of the transfer of a segment of a (1->4)-alpha-D-glucan chain to a primary hydroxyl group in a similar glucan chain.
3845	11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity	F	Catalysis of the reaction: an 11-beta-hydroxysteroid + NAD(P)+ = an 11-oxosteroid + NAD(P)H + H(+).
3846	2-acylglycerol O-acyltransferase activity	F	Catalysis of the reaction: acyl-CoA + 2-acylglycerol = CoA + diacylglycerol.
3847	1-alkyl-2-acetylglycerophosphocholine esterase activity	F	Catalysis of the reaction: 2-acetyl-1-alkyl-sn-glycero-3-phosphocholine + H2O = 1-alkyl-sn-glycero-3-phosphocholine + acetate.
3848	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity	F	Catalysis of the reaction: 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine + ATP = (2-amino-4-hydroxy-7,8-dihydropteridin-6-yl)methyl diphosphate + AMP + 2 H(+).
3849	3-deoxy-7-phosphoheptulonate synthase activity	F	Catalysis of the reaction: D-erythrose 4-phosphate + H(2)O + phosphoenolpyruvate = 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate + phosphate.
3850	2-deoxyglucose-6-phosphatase activity	F	Catalysis of the reaction: 2-deoxy-D-glucose-6-phosphate + H2O = 2-deoxy-D-glucose + phosphate.
3851	2-hydroxyacylsphingosine 1-beta-galactosyltransferase activity	F	Catalysis of the reaction: UDP-galactose + 2-(2-hydroxyacyl)sphingosine = UDP + 1-(beta-D-galactosyl)-2-(2-hydroxyacyl)sphingosine.
3852	2-isopropylmalate synthase activity	F	Catalysis of the reaction: 3-methyl-2-oxobutanoate + acetyl-CoA + H(2)O = (2S)-2-isopropylmalate + CoA + H(+).
3853	2-methylacyl-CoA dehydrogenase activity	F	Catalysis of the reaction: 2-methylbutanoyl-CoA + acceptor = 2-methylbut-2-enoyl-CoA + reduced acceptor.
3854	3-beta-hydroxy-delta5-steroid dehydrogenase activity	F	Catalysis of the reaction: a 3-beta-hydroxy-delta(5)-steroid + NAD+ = a 3-oxo-delta(5)-steroid + NADH + H(+).
3855	3-dehydroquinate dehydratase activity	F	Catalysis of the reaction: 3-dehydroquinate = 3-dehydroshikimate + H(2)O.
3856	3-dehydroquinate synthase activity	F	Catalysis of the reaction: 7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate = 3-dehydroquinate + phosphate.
3857	3-hydroxyacyl-CoA dehydrogenase activity	F	Catalysis of the reaction: (S)-3-hydroxyacyl-CoA + NAD+ = 3-oxoacyl-CoA + NADH + H(+).
3858	3-hydroxybutyrate dehydrogenase activity	F	Catalysis of the reaction: (R)-3-hydroxybutanoate + NAD(+) = acetoacetate + H(+) + NADH.
3859	3-hydroxybutyryl-CoA dehydratase activity	F	Catalysis of the reaction: (R)-3-hydroxybutanoyl-CoA = crotonoyl-CoA + H(2)O.
3860	3-hydroxyisobutyryl-CoA hydrolase activity	F	Catalysis of the reaction: 3-hydroxy-2-methylpropanoyl-CoA + H2O = CoA + 3-hydroxy-2-methylpropanoate.
3861	3-isopropylmalate dehydratase activity	F	Catalysis of the reaction: 3-isopropylmalate = 2-isopropylmaleate + H2O.
3862	3-isopropylmalate dehydrogenase activity	F	Catalysis of the reaction: 3-carboxy-2-hydroxy-4-methylpentanoate + NAD+ = 3-carboxy-4-methyl-2-oxopentanoate + NADH + H+.
3863	3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity	F	Catalysis of the reaction: 3-methyl-2-oxobutanoate + lipoamide = S-(2-methylpropanoyl)dihydrolipoamide + CO2.
3864	3-methyl-2-oxobutanoate hydroxymethyltransferase activity	F	Catalysis of the reaction: 5,10-methylenetetrahydrofolate + 3-methyl-2-oxobutanoate = tetrahydrofolate + 2-dehydropantoate.
3865	3-oxo-5-alpha-steroid 4-dehydrogenase activity	F	Catalysis of the reaction: a 3-oxo-5-alpha-steroid + acceptor = a 3-oxo-delta(4)-steroid + reduced acceptor.
3866	3-phosphoshikimate 1-carboxyvinyltransferase activity	F	Catalysis of the reaction: 3-phosphoshikimate + phosphoenolpyruvate = 5-O-(1-carboxyvinyl)-3-phosphoshikimate + phosphate.
3867	4-aminobutyrate transaminase activity	F	Catalysis of the reaction: 4-aminobutanoate + amino group acceptor = succinate semialdehyde + amino acid.
3868	4-hydroxyphenylpyruvate dioxygenase activity	F	Catalysis of the reaction: 4-hydroxyphenylpyruvate + O2 = homogentisate + CO2.
3870	5-aminolevulinate synthase activity	F	Catalysis of the reaction: glycine + H(+) + succinyl-CoA = 5-aminolevulinate + CO(2) + CoA.
3871	5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity	F	Catalysis of the reaction: 5-methyltetrahydropteroyltri-L-glutamate + L-homocysteine = L-methionine + tetrahydropteroyltri-L-glutamate.
3872	6-phosphofructokinase activity	F	Catalysis of the reaction: ATP + D-fructose-6-phosphate = ADP + D-fructose 1,6-bisphosphate.
3873	6-phosphofructo-2-kinase activity	F	Catalysis of the reaction: beta-D-fructose 6-phosphate + ATP = beta-D-fructose 2,6-bisphosphate + ADP + 2 H(+).
3874	6-pyruvoyltetrahydropterin synthase activity	F	Catalysis of the reaction: 7,8-dihydroneopterin 3'-triphosphate = 6-pyruvoyl-5,6,7,8-tetrahydropterin + H(+) + triphosphate.
3875	ADP-ribosylarginine hydrolase activity	F	Catalysis of the reaction: N2-(ADP-D-ribosyl)-L-arginine + H2O = L-arginine + ADP-ribose.
3876	AMP deaminase activity	F	Catalysis of the reaction: AMP + H2O = IMP + NH3.
3877	ATP adenylyltransferase activity	F	Catalysis of the reaction: ADP + ATP = phosphate + P(1),P(4)-bis(5'-adenosyl)tetraphosphate.
3878	ATP citrate synthase activity	F	Catalysis of the reaction: acetyl-CoA + ADP + H(+) + oxaloacetate + phosphate = ATP + citrate + CoA.
3879	ATP phosphoribosyltransferase activity	F	Catalysis of the reaction: 1-(5-phospho-D-ribosyl)-ATP + diphosphate = ATP + 5-phospho-alpha-D-ribose 1-diphosphate.
3880	protein C-terminal carboxyl O-methyltransferase activity	F	Catalysis of the transfer of a methyl group to the oxygen atom of a carboxyl group at the C-terminal of a protein.
3881	CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity	F	Catalysis of the reaction: myo-inositol + CDP-diacylglycerol = 1-phosphatidyl-1D-myo-inositol + CMP + H(+).
3882	CDP-diacylglycerol-serine O-phosphatidyltransferase activity	F	Catalysis of the reaction: CDP-diacylglycerol + L-serine = CMP + O-sn-phosphatidyl-L-serine.
3883	CTP synthase activity	F	Catalysis of the reaction: ATP + UTP + NH3 = ADP + phosphate + CTP.
3884	D-amino-acid oxidase activity	F	Catalysis of the reaction: a D-amino acid + H2O + O2 = a 2-oxo acid + NH3 + hydrogen peroxide.
3885	D-arabinono-1,4-lactone oxidase activity	F	Catalysis of the reaction: D-arabinono-1,4-lactone + O(2) = dehydro-D-arabinono-1,4-lactone + H(2)O(2) + H(+).
3886	DNA (cytosine-5-)-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + DNA containing cytosine = S-adenosyl-L-homocysteine + DNA containing 5-methylcytosine.
3887	DNA-directed DNA polymerase activity	F	Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1); the synthesis of DNA from deoxyribonucleotide triphosphates in the presence of a DNA template and a 3'hydroxyl group.
3896	DNA primase activity	F	Catalysis of the synthesis of a short RNA primer on a DNA template, providing a free 3'-OH that can be extended by DNA-directed DNA polymerases.
3899	DNA-directed 5'-3' RNA polymerase activity	F	Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). Utilizes a DNA template, i.e. the catalysis of DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. Can initiate a chain 'de novo'.
3904	deoxyribodipyrimidine photo-lyase activity	F	Catalysis of the reaction: cyclobutadipyrimidine (in DNA) = 2 pyrimidine residues (in DNA). This reaction represents the reactivation of irradiated DNA by light.
3905	alkylbase DNA N-glycosylase activity	F	Catalysis of the reaction: DNA with alkylated base + H2O = DNA with abasic site + alkylated base. This reaction is the hydrolysis of DNA by cleavage of the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar to remove an alkylated base, leaving an apyrimidinic or apurinic site.
3906	DNA-(apurinic or apyrimidinic site) lyase activity	F	Catalysis of the cleavage of the C-O-P bond 3' to the apurinic or apyrimidinic site in DNA by a beta-elimination reaction, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.
3908	methylated-DNA-[protein]-cysteine S-methyltransferase activity	F	Catalysis of the reaction: DNA (containing 6-O-methylguanine) + (protein)-L-cysteine = DNA (without 6-O-methylguanine) + protein S-methyl-L-cysteine.
3909	DNA ligase activity	F	Catalysis of the formation of a phosphodiester bond between the 3'-hydroxyl group at the end of one DNA chain and the 5'-phosphate group at the end of another. This reaction requires an energy source such as ATP or NAD+.
3910	DNA ligase (ATP) activity	F	Catalysis of the reaction: ATP + deoxyribonucleotide(n) + deoxyribonucleotide(m) = AMP + diphosphate + deoxyribonucleotide(n+m).
3911	DNA ligase (NAD+) activity	F	Catalysis of the reaction: NAD+ + deoxyribonucleotide(n) + deoxyribonucleotide(m) = AMP + nicotinamide nucleotide + deoxyribonucleotide(n+m).
3912	DNA nucleotidylexotransferase activity	F	Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).
3913	DNA photolyase activity	F	Catalysis of the repair of a photoproduct resulting from ultraviolet irradiation of two adjacent pyrimidine residues in DNA.
3914	DNA (6-4) photolyase activity	F	Catalysis of the reaction: pyrimidine-pyrimidone (6-4) photoproduct (in DNA) = 2 pyrimidine residues (in DNA). Catalyzes the reactivation of ultraviolet-irradiated DNA.
3916	DNA topoisomerase activity	F	Catalysis of the transient cleavage and passage of individual DNA strands or double helices through one another, resulting a topological transformation in double-stranded DNA.
3917	DNA topoisomerase type I activity	F	Catalysis of a DNA topological transformation by transiently cleaving one DNA strand at a time to allow passage of another strand; changes the linking number by +1 per catalytic cycle.
3918	DNA topoisomerase type II (ATP-hydrolyzing) activity	F	Catalysis of a DNA topological transformation by transiently cleaving a pair of complementary DNA strands to form a gate through which a second double-stranded DNA segment is passed, after which the severed strands in the first DNA segment are rejoined; product release is coupled to ATP binding and hydrolysis; changes the linking number in multiples of 2.
3919	FMN adenylyltransferase activity	F	Catalysis of the reaction: ATP + FMN = diphosphate + FAD.
3920	GMP reductase activity	F	Catalysis of the reaction: IMP + NADP(+) + NH(4)(+) = GMP + 2 H(+) + NADPH.
3921	GMP synthase activity	F	Catalysis of the reaction: ATP + xanthosine 5'-phosphate + NH3 = AMP + diphosphate + GMP.
3922	GMP synthase (glutamine-hydrolyzing) activity	F	Catalysis of the reaction: ATP + xanthosine 5'-phosphate + L-glutamine + H2O = AMP + diphosphate + GMP + L-glutamate.
3923	GPI-anchor transamidase activity	F	Catalysis of the formation of the linkage between a protein and a glycosylphosphatidylinositol anchor. The reaction probably occurs by subjecting a peptide bond to nucleophilic attack by the amino group of ethanolamine-GPI, transferring the protein from a signal peptide to the GPI anchor.
3924	GTPase activity	F	Catalysis of the reaction: GTP + H2O = GDP + phosphate.
3933	GTP cyclohydrolase activity	F	Catalysis of the hydrolysis of the imidazole ring of GTP, releasing formate. Two C-N bonds are hydrolyzed and the pentase unit is isomerized.
3934	GTP cyclohydrolase I activity	F	Catalysis of the reaction: GTP + H2O = formate + 7,8-dihydroneopterin 3'-triphosphate.
3935	GTP cyclohydrolase II activity	F	Catalysis of the reaction: GTP + 3 H(2)O = 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)-pyrimidine + diphosphate + formate + 3 H(+).
3937	IMP cyclohydrolase activity	F	Catalysis of the reaction: IMP + H2O = 5-formamido-1-(5-phosphoribosyl)imidazole-4-carboxamide.
3938	IMP dehydrogenase activity	F	Catalysis of the reaction: inosine 5'-phosphate + NAD+ + H2O = xanthosine 5'-phosphate + NADH + H+.
3939	L-iditol 2-dehydrogenase activity	F	Catalysis of the reaction: L-iditol + NAD+ = L-sorbose + NADH + H+.
3940	L-iduronidase activity	F	Catalysis of the hydrolysis of alpha-L-iduronosidic linkages in dermatan sulfate.
3941	L-serine ammonia-lyase activity	F	Catalysis of the reaction: L-serine = pyruvate + NH3.
3942	N-acetyl-gamma-glutamyl-phosphate reductase activity	F	Catalysis of the reaction: N-acetyl-L-glutamate 5-semialdehyde + NADP+ + phosphate = N-acetyl-5-glutamyl phosphate + NADPH + H+.
3943	N-acetylgalactosamine-4-sulfatase activity	F	Catalysis of the hydrolysis of the 4-sulfate groups of the N-acetyl-D-galactosamine 4-sulfate units of chondroitin sulfate and dermatan sulfate.
3944	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase activity	F	Catalysis of the reaction: glycoprotein N-acetyl-D-glucosaminyl-phospho-D-mannose + H2O = N-acetyl-D-glucosamine + glycoprotein phospho-D-mannose.
3945	N-acetyllactosamine synthase activity	F	Catalysis of the reaction: UDP-galactose + N-acetyl-D-glucosamine = UDP + N-acetyllactosamine.
3947	(N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase activity	F	Catalysis of the reaction: UDP-N-acetyl-D-galactosamine + (N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide = UDP + N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide.
3948	N4-(beta-N-acetylglucosaminyl)-L-asparaginase activity	F	Catalysis of the reaction: N(4)-(beta-N-acetyl-D-glucosaminyl)-L-asparagine + H(2)O = N-acetyl-beta-D-glucosaminylamine + L-aspartate + H(+).
3949	1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase activity	F	Catalysis of the reaction: 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide = 5-[(5-phospho-1-deoxy-D-ribulos-1-ylimino)methylamino]-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide.
3950	NAD+ ADP-ribosyltransferase activity	F	Catalysis of the reaction: NAD+ + (ADP-D-ribosyl)(n)-acceptor = nicotinamide + (ADP-D-ribosyl)(n+1)-acceptor.
3951	NAD+ kinase activity	F	Catalysis of the reaction: ATP + NAD(+) = ADP + 2 H(+) + NADP(+).
3952	NAD+ synthase (glutamine-hydrolyzing) activity	F	Catalysis of the reaction: ATP + deamido-NAD+ + L-glutamine + H2O = AMP + diphosphate + NAD+ + L-glutamate.
3953	NAD+ nucleosidase activity	F	Catalysis of the reaction: NAD+ + H2O = nicotinamide + ADP-ribose.
3954	NADH dehydrogenase activity	F	Catalysis of the reaction: NADH + H+ + acceptor = NAD+ + reduced acceptor.
3955	NAD(P)H dehydrogenase (quinone) activity	F	Catalysis of the reaction: NAD(P)H + H+ + a quinone = NAD(P)+ + a hydroquinone.
3956	NAD(P)+-protein-arginine ADP-ribosyltransferase activity	F	Catalysis of the reaction: NAD(P)+ + L-arginine = nicotinamide + N2-(ADP-D-ribosyl)-L-arginine.
3957	NAD(P)+ transhydrogenase (B-specific) activity	F	Catalysis of the reaction: NADPH + H+ + NAD+ = NADP+ + NADH + H+, driving the transfer of a solute or solutes from one side of a membrane to the other. In the course of the reaction (left to right) one H atom is transferred from inside the cell to outside. The reaction is B-specific (i.e. the pro-S hydrogen is transferred from the 4-position of reduced nicotinamide cofactor) with respect to both NAD+ and NADP+.
3958	NADPH-hemoprotein reductase activity	F	Catalysis of the reaction: NADPH + H+ + n oxidized hemoprotein = NADP+ + n reduced hemoprotein.
3959	NADPH dehydrogenase activity	F	Catalysis of the reaction: NADPH + H+ + acceptor = NADP+ + reduced acceptor.
3960	NADPH:quinone reductase activity	F	Catalysis of the reaction: NADPH + H+ + quinone = NADP+ + semiquinone.
3961	O-acetylhomoserine aminocarboxypropyltransferase activity	F	Catalysis of the reaction: O-acetyl-L-homoserine + methanethiol = L-methionine + acetate. Also reacts with other thiols and H2S, producing homocysteine or thioethers.
3962	cystathionine gamma-synthase activity	F	Catalysis of the reaction: O-succinyl-L-homoserine + L-cysteine = cystathionine + succinate.
3963	RNA-3'-phosphate cyclase activity	F	Catalysis of the reaction: ATP + RNA 3'-terminal-phosphate = AMP + diphosphate + RNA terminal-2',3'-cyclic-phosphate.
3964	RNA-directed DNA polymerase activity	F	Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). Catalyzes RNA-template-directed extension of the 3'- end of a DNA strand by one deoxynucleotide at a time.
3968	RNA-directed 5'-3' RNA polymerase activity	F	Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1); uses an RNA template, i.e. the catalysis of RNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time.
3972	RNA ligase (ATP) activity	F	Catalysis of the reaction: ATP + ribonucleotide(n) + ribonucleotide(m) = AMP + diphosphate + ribonucleotide(n+m).
3973	(S)-2-hydroxy-acid oxidase activity	F	Catalysis of the reaction: (S)-2-hydroxy-acid + O2 = 2-oxo acid + hydrogen peroxide.
3974	UDP-N-acetylglucosamine 4-epimerase activity	F	Catalysis of the reaction: UDP-N-acetyl-D-glucosamine = UDP-N-acetyl-D-galactosamine.
3975	UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase activity	F	Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + dolichyl phosphate = UMP + N-acetyl-D-glucosaminyl-diphosphodolichol.
3976	UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity	F	Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + lysosomal-enzyme D-mannose = UMP + lysosomal-enzyme N-acetyl-D-glucosaminyl-phospho-D-mannose.
3977	UDP-N-acetylglucosamine diphosphorylase activity	F	Catalysis of the reaction: N-acetyl-alpha-D-glucosamine 1-phosphate + UTP = diphosphate + UDP-N-acetyl-alpha-D-glucosamine.
3978	UDP-glucose 4-epimerase activity	F	Catalysis of the reaction: UDP-glucose = UDP-galactose.
3979	UDP-glucose 6-dehydrogenase activity	F	Catalysis of the reaction: H(2)O + 2 NAD(+) + UDP-alpha-D-glucose = 3 H(+) + 2 NADH + UDP-alpha-D-glucuronate.
3980	UDP-glucose:glycoprotein glucosyltransferase activity	F	Catalysis of the addition of UDP-glucose on to asparagine-linked (N-linked) oligosaccharides of the form Man7-9GlcNAc2 on incorrectly folded glycoproteins.
3983	UTP:glucose-1-phosphate uridylyltransferase activity	F	Catalysis of the reaction: alpha-D-glucose 1-phosphate + UTP = diphosphate + UDP-D-glucose.
3984	acetolactate synthase activity	F	Catalysis of the reaction: 2 pyruvate = 2-acetolactate + CO2.
3985	acetyl-CoA C-acetyltransferase activity	F	Catalysis of the reaction: 2 acetyl-CoA = CoA + acetoacetyl-CoA.
3986	acetyl-CoA hydrolase activity	F	Catalysis of the reaction: acetyl-CoA + H(2)O = acetate + CoA + H(+).
3987	acetate-CoA ligase activity	F	Catalysis of the reaction: ATP + acetate + CoA = AMP + diphosphate + acetyl-CoA.
3988	acetyl-CoA C-acyltransferase activity	F	Catalysis of the reaction: acyl-CoA + acetyl-CoA = CoA + 3-oxoacyl-CoA.
3989	acetyl-CoA carboxylase activity	F	Catalysis of the reaction: ATP + acetyl-CoA + HCO3- = ADP + phosphate + malonyl-CoA.
3990	acetylcholinesterase activity	F	Catalysis of the reaction: acetylcholine + H2O = choline + acetate.
3991	acetylglutamate kinase activity	F	Catalysis of the reaction: ATP + N-acetyl-L-glutamate = ADP + N-acetyl-L-glutamate-5-phosphate.
3992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity	F	Catalysis of the reaction: 2-oxoglutarate + N(2)-acetyl-L-ornithine = N-acetyl-L-glutamate 5-semialdehyde + L-glutamate.
3993	acid phosphatase activity	F	Catalysis of the reaction: an orthophosphoric monoester + H2O = an alcohol + phosphate, with an acid pH optimum.
3994	aconitate hydratase activity	F	Catalysis of the reaction: citrate = isocitrate. The reaction occurs in two steps: (1) citrate = cis-aconitate + H2O, (2) cis-aconitate + H2O = isocitrate. This reaction is the interconversion of citrate and isocitrate via the labile, enzyme-bound intermediate cis-aconitate. Water is removed from one part of the citrate molecule and added back to a different atom to form isocitrate.
3995	acyl-CoA dehydrogenase activity	F	Catalysis of the reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor.
3996	acyl-CoA ligase activity	F	Catalysis of the reaction: ATP + a long-chain carboxylic acid + CoA = AMP + diphosphate + an acyl-CoA; long-chain fatty acids have chain lengths of C13 to C22.
3997	acyl-CoA oxidase activity	F	Catalysis of the reaction: acyl-CoA + O2 = trans-2,3-dehydroacyl-CoA + hydrogen peroxide.
3998	acylphosphatase activity	F	Catalysis of the reaction: an acyl phosphate + H2O = a carboxylate + phosphate.
3999	adenine phosphoribosyltransferase activity	F	Catalysis of the reaction: AMP + diphosphate = adenine + 5-phospho-alpha-D-ribose 1-diphosphate.
4000	adenosine deaminase activity	F	Catalysis of the reaction: adenosine + H2O = inosine + NH3.
4001	adenosine kinase activity	F	Catalysis of the reaction: ATP + adenosine = ADP + AMP.
4003	ATP-dependent DNA helicase activity	F	Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction drives the unwinding of the DNA helix.
4004	ATP-dependent RNA helicase activity	F	Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction drives the unwinding of an RNA helix.
4008	copper-exporting ATPase activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Cu2+(in) -> ADP + phosphate + Cu2+(out).
4012	phospholipid-translocating ATPase activity	F	Catalysis of the movement of phospholipids from one membrane bilayer leaflet to the other, driven by the hydrolysis of ATP.
4013	adenosylhomocysteinase activity	F	Catalysis of the reaction: S-adenosyl-L-homocysteine + H2O = adenosine + L-homocysteine.
4014	adenosylmethionine decarboxylase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + H(+) = S-adenosylmethioninamine + CO(2).
4015	adenosylmethionine-8-amino-7-oxononanoate transaminase activity	F	Catalysis of the reaction: 8-amino-7-oxononanoate + S-adenosyl-L-methionine(1+) = 7,8-diaminononanoate + S-adenosyl-4-methylthio-2-oxobutanoate.
4016	adenylate cyclase activity	F	Catalysis of the reaction: ATP = 3',5'-cyclic AMP + diphosphate.
4017	adenylate kinase activity	F	Catalysis of the reaction: ATP + AMP = 2 ADP.
4018	N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity	F	Catalysis of the reaction: N6-(1,2-dicarboxyethyl)AMP = fumarate + AMP.
4019	adenylosuccinate synthase activity	F	Catalysis of the reaction: L-aspartate + GTP + IMP = N(6)-(1,2-dicarboxyethyl)-AMP + GDP + 3 H(+) + phosphate.
4020	adenylylsulfate kinase activity	F	Catalysis of the reaction: ATP + adenylylsulfate = ADP + 3'-phosphoadenosine 5'-phosphosulfate.
4021	L-alanine:2-oxoglutarate aminotransferase activity	F	Catalysis of the reaction: 2-oxoglutarate + L-alanine = L-glutamate + pyruvate.
4022	alcohol dehydrogenase (NAD) activity	F	Catalysis of the reaction: an alcohol + NAD+ = an aldehyde or ketone + NADH + H+.
4023	alcohol dehydrogenase activity, metal ion-independent	F	Catalysis of the reaction: an alcohol + NAD+ = an aldehyde or ketone + NADH + H+; can proceed in the absence of a metal ion.
4024	alcohol dehydrogenase activity, zinc-dependent	F	Catalysis of the reaction: an alcohol + NAD+ = an aldehyde or ketone + NADH + H+, requiring the presence of zinc.
4025	alcohol dehydrogenase activity, iron-dependent	F	Catalysis of the reaction: an alcohol + NAD+ = an aldehyde or ketone + NADH + H+, requiring the presence of iron.
4026	alcohol O-acetyltransferase activity	F	Catalysis of the reaction: acetyl-CoA + an alcohol = CoA + an acetyl ester.
4027	alcohol sulfotransferase activity	F	Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + an alcohol = adenosine 3',5'-bisphosphate + an alkyl sulfate.
4028	3-chloroallyl aldehyde dehydrogenase activity	F	Catalysis of the reaction: 3-chloroallyl aldehyde + H2O = 2 H+ + 2 e- + 3-chloroacrylic acid.
4029	aldehyde dehydrogenase (NAD) activity	F	Catalysis of the reaction: an aldehyde + NAD+ + H2O = an acid + NADH + H+.
4030	aldehyde dehydrogenase [NAD(P)+] activity	F	Catalysis of the reaction: an aldehyde + NAD(P)+ + H2O = an acid + NAD(P)H + H+.
4031	aldehyde oxidase activity	F	Catalysis of the reaction: an aldehyde + H2O + O2 = a carboxylic acid + hydrogen peroxide.
4032	alditol:NADP+ 1-oxidoreductase activity	F	Catalysis of the reaction: an alditol + NADP+ = an aldose + NADPH + H+.
4033	aldo-keto reductase (NADP) activity	F	Catalysis of the reaction: an alcohol + NADP+ = an aldehyde or a ketone + NADPH + H+.
4034	aldose 1-epimerase activity	F	Catalysis of the reaction: alpha-D-glucose = beta-D-glucose. Also acts on L-arabinose, D-xylose, D-galactose, maltose and lactose.
4035	alkaline phosphatase activity	F	Catalysis of the reaction: an orthophosphoric monoester + H2O = an alcohol + phosphate, with an alkaline pH optimum.
4037	allantoicase activity	F	Catalysis of the reaction: allantoate + H(2)O = (S)-ureidoglycolate + urea.
4038	allantoinase activity	F	Catalysis of the reaction: allantoin + H2O = allantoate.
4039	allophanate hydrolase activity	F	Catalysis of the reaction: H(2)O + 3 H(+) + urea-1-carboxylate = 2 CO(2) + 2 NH(4)(+).
4040	amidase activity	F	Catalysis of the reaction: a monocarboxylic acid amide + H2O = a monocarboxylate + NH3.
4042	acetyl-CoA:L-glutamate N-acetyltransferase activity	F	Catalysis of the reaction: L-glutamate + acetyl-CoA = N-acetyl-L-glutamate + CoA + H(+).
4043	L-aminoadipate-semialdehyde dehydrogenase activity	F	Catalysis of the reaction: L-2-aminoadipate 6-semialdehyde + NADP+ + H2O = L-2-aminoadipate + NADPH + H+.
4044	amidophosphoribosyltransferase activity	F	Catalysis of the reaction: 5-phospho-beta-D-ribosylamine + L-glutamate + diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate + L-glutamine + H(2)O.
4045	aminoacyl-tRNA hydrolase activity	F	Catalysis of the reaction: N-substituted aminoacyl-tRNA + H2O = N-substituted amino acid + tRNA.
4046	aminoacylase activity	F	Catalysis of the reaction: an N-acyl-L-amino acid + H2O = a carboxylate + an L-amino acid.
4047	aminomethyltransferase activity	F	Catalysis of the reaction: (6S)-tetrahydrofolate + S-aminomethyldihydrolipoylprotein = (6R)-5,10-methylenetetrahydrofolate + NH3 + dihydrolipoylprotein.
4048	anthranilate phosphoribosyltransferase activity	F	Catalysis of the reaction: N-(5-phospho-beta-D-ribosyl)anthranilate + diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate + anthranilate.
4049	anthranilate synthase activity	F	Catalysis of the reaction: chorismate + L-glutamine = anthranilate + pyruvate + L-glutamate.
4051	arachidonate 5-lipoxygenase activity	F	Catalysis of the reaction: arachidonate + O2 = (6E,8Z,11Z,14Z)-(5S)-5-hydroperoxycosa-6,8,11,14-tetraenoate.
4052	arachidonate 12-lipoxygenase activity	F	Catalysis of the reaction: arachidonate + O(2) = (5Z,8Z,10E,12S,14Z)-12-hydroperoxyicosa-5,8,10,14-tetraenoate.
4053	arginase activity	F	Catalysis of the reaction: L-arginine + H2O = L-ornithine + urea.
4054	arginine kinase activity	F	Catalysis of the reaction: L-arginine + ATP = N(omega)-phospho-L-arginine + ADP + 2 H(+).
4055	argininosuccinate synthase activity	F	Catalysis of the reaction: ATP + L-citrulline + L-aspartate = AMP + diphosphate + (N(omega)-L-arginino)succinate.
4056	argininosuccinate lyase activity	F	Catalysis of the reaction: N-(L-arginino)succinate = fumarate + L-arginine.
4057	arginyltransferase activity	F	Catalysis of the reaction: L-arginyl-tRNA + protein = tRNA + L-arginyl-protein.
4058	aromatic-L-amino-acid decarboxylase activity	F	Catalysis of the reaction: L-amino acid + H+ = R-H + CO2.
4059	aralkylamine N-acetyltransferase activity	F	Catalysis of the reaction: acetyl-CoA + an aralkylamine = CoA + an N-acetylaralkylamine.
4060	arylamine N-acetyltransferase activity	F	Catalysis of the reaction: acetyl-CoA + an arylamine = CoA + an N-acetylarylamine.
4061	arylformamidase activity	F	Catalysis of the reaction: N-formyl-L-kynurenine + H2O = formate + L-kynurenine.
4062	aryl sulfotransferase activity	F	Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + a phenol = adenosine 3',5'-bisphosphate + an aryl sulfate.
4063	aryldialkylphosphatase activity	F	Catalysis of the reaction: aryl dialkyl phosphate + H2O = dialkyl phosphate + an aryl alcohol.
4064	arylesterase activity	F	Catalysis of the reaction: a phenyl acetate + H2O = a phenol + acetate.
4065	arylsulfatase activity	F	Catalysis of the reaction: a phenol sulfate + H2O = a phenol + sulfate.
4066	asparagine synthase (glutamine-hydrolyzing) activity	F	Catalysis of the reaction: ATP + L-aspartate + L-glutamine = AMP + diphosphate + L-asparagine + L-glutamate.
4067	asparaginase activity	F	Catalysis of the reaction: L-asparagine + H2O = L-aspartate + NH3.
4068	aspartate 1-decarboxylase activity	F	Catalysis of the reaction: L-aspartate = beta-alanine + CO2.
4069	L-aspartate:2-oxoglutarate aminotransferase activity	F	Catalysis of the reaction: L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate.
4070	aspartate carbamoyltransferase activity	F	Catalysis of the reaction: L-aspartate + carbamoyl phosphate = N-carbamoyl-L-aspartate + H(+) + phosphate.
4071	aspartate-ammonia ligase activity	F	Catalysis of the reaction: ATP + L-aspartate + NH3 = AMP + diphosphate + L-asparagine.
4072	aspartate kinase activity	F	Catalysis of the reaction: L-aspartate + ATP = 4-phospho-L-aspartate + ADP + H(+).
4073	aspartate-semialdehyde dehydrogenase activity	F	Catalysis of the reaction: L-aspartate 4-semialdehyde + NADP(+) + phosphate = 4-phospho-L-aspartate + H(+) + NADPH.
4074	biliverdin reductase activity	F	Catalysis of the reaction: bilirubin + NAD(P)+ = biliverdin + NAD(P)H + H+.
4075	biotin carboxylase activity	F	Catalysis of the reaction: ATP + biotin-carboxyl-carrier protein + CO2 = ADP + phosphate + carboxybiotin-carboxyl-carrier protein.
4076	biotin synthase activity	F	Catalysis of the reaction: 2 S-adenosyl-L-methionine + dethiobiotin + S(2-) = 2 5'-deoxyadenosine + 2 L-methionine + biotin + H(+).
4077	biotin-[acetyl-CoA-carboxylase] ligase activity	F	Catalysis of the reaction: ATP + biotin + apo-(acetyl-CoA:carbon-dioxide ligase (ADP forming)) = AMP + diphosphate + (acetyl-CoA:carbon-dioxide ligase (ADP forming)).
4078	biotin-[methylcrotonoyl-CoA-carboxylase] ligase activity	F	Catalysis of the reaction: ATP + biotin + apo-(3-methylcrotonoyl-CoA:carbon-dioxide ligase (ADP-forming)) = AMP + diphosphate + (3-methylcrotonoyl-CoA:carbon-dioxide ligase (ADP-forming)).
4079	biotin-[methylmalonyl-CoA-carboxytransferase] ligase activity	F	Catalysis of the reaction: ATP + biotin + apo-(methylmalonyl-CoA:pyruvate carboxytransferase) = AMP + diphosphate + (methylmalonyl-CoA:pyruvate carboxytransferase).
4080	biotin-[propionyl-CoA-carboxylase (ATP-hydrolyzing)] ligase activity	F	Catalysis of the reaction: ATP + biotin + apo-(propanoyl-CoA:carbon-dioxide ligase (ADP-forming)) = AMP + diphosphate + (propanoyl-CoA:carbon-dioxide ligase (ADP-forming)).
4081	bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) activity	F	Catalysis of the reaction: P(1),P(4)-bis(5'-nucleosyl)tetraphosphate + H2O = NTP + NMP. Acts on bis(5'-guanosyl)-, bis(5'-xanthosyl)-, bis(5'-adenosyl)- and bis(5'-uridyl)-tetraphosphate.
4082	bisphosphoglycerate mutase activity	F	Catalysis of the reaction: 3-phospho-D-glyceroyl phosphate = 2,3-bisphospho-D-glycerate.
4083	bisphosphoglycerate 2-phosphatase activity	F	Catalysis of the reaction: 2,3-bisphospho-D-glycerate + H(2)O = 3-phospho-D-glycerate + phosphate.
4084	branched-chain-amino-acid transaminase activity	F	Catalysis of the reaction: a branched-chain amino acid + 2-oxoglutarate = L-glutamate + a 2-oxocarboxylate derived from the branched-chain amino acid.
4085	butyryl-CoA dehydrogenase activity	F	Catalysis of the reaction: butanoyl-CoA + electron-transfer flavoprotein = 2-butenoyl-CoA + reduced electron-transfer flavoprotein.
4087	carbamoyl-phosphate synthase (ammonia) activity	F	Catalysis of the reaction: 2 ATP + CO(2) + H(2)O + NH(4)(+) = 2 ADP + carbamoyl phosphate + 5 H(+) + phosphate.
4088	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity	F	Catalysis of the reaction: 2 ATP + L-glutamine + CO2 + H2O = 2 ADP + phosphate + glutamate + carbamoyl phosphate.
4089	carbonate dehydratase activity	F	Catalysis of the reaction: H2CO3 = CO2 + H2O.
4090	carbonyl reductase (NADPH) activity	F	Catalysis of the reaction: R-CHOH-R' + NADP+ = R-CO-R' + NADPH + H+.
4092	carnitine O-acetyltransferase activity	F	Catalysis of the reaction: acetyl-CoA + carnitine = (R)-O-acetylcarnitine + CoA.
4095	carnitine O-palmitoyltransferase activity	F	Catalysis of the reaction: palmitoyl-CoA + L-carnitine = CoA + L-palmitoylcarnitine.
4096	catalase activity	F	Catalysis of the reaction: 2 hydrogen peroxide = O2 + 2 H2O.
4097	catechol oxidase activity	F	Catalysis of the reaction: 2 catechol + O2 = 2 1,2-benzoquinone + 2 H2O.
4098	cerebroside-sulfatase activity	F	Catalysis of the reaction: a cerebroside 3-sulfate + H2O = a cerebroside + sulfate.
4099	chitin deacetylase activity	F	Catalysis of the reaction: chitin + H2O = chitosan + acetate.
4100	chitin synthase activity	F	Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + [->4)-N-acetyl-beta-D-glucosaminyl-(1-](n) = UDP + [->4)-N-acetyl-beta-D-glucosaminyl-(1-](n+1).
4102	choline O-acetyltransferase activity	F	Catalysis of the reaction: acetyl-CoA + choline = acetylcholine + CoA.
4103	choline kinase activity	F	Catalysis of the reaction: ATP + choline = ADP + choline phosphate + 2 H(+).
4104	cholinesterase activity	F	Catalysis of the reaction: an acylcholine + H2O = choline + a carboxylic acid anion.
4105	choline-phosphate cytidylyltransferase activity	F	Catalysis of the reaction: CTP + choline phosphate = diphosphate + CDP-choline.
4106	chorismate mutase activity	F	Catalysis of the reaction: chorismate = prephenate.
4107	chorismate synthase activity	F	Catalysis of the reaction: 5-O-(1-carboxyvinyl)-3-phosphoshikimate = chorismate + phosphate.
4108	citrate (Si)-synthase activity	F	Catalysis of the reaction: acetyl-CoA + H2O + oxaloacetate = citrate + CoA, where the acetyl group is added to the si-face of oxaloacetate; acetyl-CoA thus provides the two carbon atoms of the pro-S carboxymethyl group.
4109	coproporphyrinogen oxidase activity	F	Catalysis of the reaction: coproporphyrinogen III + 2 H(+) + O(2) = 2 CO(2) + 2 H(2)O + protoporphyrinogen IX.
4110	corticosteroid side-chain-isomerase activity	F	Catalysis of the reaction: 11-deoxycorticosterone = 20-hydroxy-3-oxopregn-4-en-21-al.
4111	creatine kinase activity	F	Catalysis of the reaction: ATP + creatine = N-phosphocreatine + ADP + 2 H(+).
4112	cyclic-nucleotide phosphodiesterase activity	F	Catalysis of the reaction: a nucleoside cyclic phosphate + H2O = a nucleoside phosphate.
4113	2',3'-cyclic-nucleotide 3'-phosphodiesterase activity	F	Catalysis of the reaction: nucleoside 2',3'-cyclic phosphate + H2O = nucleoside 2'-phosphate.
4114	3',5'-cyclic-nucleotide phosphodiesterase activity	F	Catalysis of the reaction: nucleoside 3',5'-cyclic phosphate + H2O = nucleoside 5'-phosphate.
4115	3',5'-cyclic-AMP phosphodiesterase activity	F	Catalysis of the reaction: adenosine 3',5'-cyclic phosphate + H2O = adenosine 5'-phosphate.
4117	calmodulin-dependent cyclic-nucleotide phosphodiesterase activity	F	Catalysis of the reaction: nucleoside 3',5'-cyclic phosphate + H2O = nucleoside 5'-phosphate; catalytic activity is regulated by calmodulin.
4118	cGMP-stimulated cyclic-nucleotide phosphodiesterase activity	F	Catalysis of the reaction: nucleoside 3',5'-cyclic phosphate + H2O = nucleoside 5'-phosphate; catalytic activity is increased in the presence of cGMP.
4119	cGMP-inhibited cyclic-nucleotide phosphodiesterase activity	F	Catalysis of the reaction: nucleoside 3',5'-cyclic phosphate + H2O = nucleoside 5'-phosphate; catalytic activity is decreased in the presence of cGMP.
4120	photoreceptor cyclic-nucleotide phosphodiesterase activity	F	Catalysis of the reaction: nucleoside cyclic phosphate + H2O = nucleoside phosphate. This reaction is the hydrolysis of bonds in a cyclic nucleotide.
4121	cystathionine beta-lyase activity	F	Catalysis of the reaction: cystathionine + H2O = L-homocysteine + NH3 + pyruvate.
4122	cystathionine beta-synthase activity	F	Catalysis of the reaction: L-serine + L-homocysteine = cystathionine + H2O.
4123	cystathionine gamma-lyase activity	F	Catalysis of the reaction: L-cystathionine + H2O = 2-oxobutanoate + L-cysteine + NH4+.
4124	cysteine synthase activity	F	Catalysis of the reaction: O3-acetyl-L-serine + hydrogen sulfide = L-cysteine + acetate.
4125	L-seryl-tRNASec selenium transferase activity	F	Catalysis of the reaction: L-seryl-tRNA(Sec) + selenophosphate = L-selenocysteinyl-tRNA(Sec) + H2O + phosphate.
4126	cytidine deaminase activity	F	Catalysis of the reaction: cytidine + H2O = uridine + NH3.
4127	cytidylate kinase activity	F	Catalysis of the reaction: ATP + (d)CMP = ADP + (d)CDP.
4128	cytochrome-b5 reductase activity, acting on NAD(P)H	F	Catalysis of the reaction: NAD(P)H + H+ + 2 ferricytochrome b(5) = NAD(P)+ + 2 ferrocytochrome b(5).
4129	cytochrome-c oxidase activity	F	Catalysis of the reaction: 4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.
4130	cytochrome-c peroxidase activity	F	Catalysis of the reaction: 2 ferrocytochrome c + hydrogen peroxide = 2 ferricytochrome c + 2 H2O.
4131	cytosine deaminase activity	F	Catalysis of the reaction: cytosine + H2O = uracil + NH3.
4132	dCMP deaminase activity	F	Catalysis of the reaction: dCMP + H2O = dUMP + NH3.
4133	glycogen debranching enzyme activity	F	Catalysis of the cleavage of branch points in branched glycogen polymers.
4134	4-alpha-glucanotransferase activity	F	Catalysis of the transfer of a segment of a (1->4)-alpha-D-glucan to a new 4-position in an acceptor, which may be glucose or (1->4)-alpha-D-glucan.
4135	amylo-alpha-1,6-glucosidase activity	F	Catalysis of the hydrolysis of (1->6)-alpha-D-glucosidic branch linkages in glycogen phosphorylase limit dextrin. Limit dextrin is the highly branched core that remains after exhaustive treatment of glycogen with glycogen phosphorylase. It is formed because these enzymes cannot hydrolyze the (1->6) glycosidic linkages present.
4136	deoxyadenosine kinase activity	F	Catalysis of the reaction: 2'-deoxyadenosine + ATP = ADP + dAMP + 2 H(+).
4137	deoxycytidine kinase activity	F	Catalysis of the reaction: NTP + deoxycytidine = NDP + CMP.
4138	deoxyguanosine kinase activity	F	Catalysis of the reaction: 2'-deoxyguanosine + ATP = ADP + dGMP + 2 H(+).
4139	deoxyribose-phosphate aldolase activity	F	Catalysis of the reaction: 2-deoxy-D-ribose 5-phosphate = D-glyceraldehyde 3-phosphate + acetaldehyde.
4140	dephospho-CoA kinase activity	F	Catalysis of the reaction: 3'-dephospho-CoA + ATP = ADP + CoA + 2 H(+).
4141	dethiobiotin synthase activity	F	Catalysis of the reaction: 7,8-diaminononanoate + ATP + CO(2) = ADP + dethiobiotin + 4 H(+) + phosphate.
4142	diacylglycerol cholinephosphotransferase activity	F	Catalysis of the reaction: CDP-choline + 1,2-diacylglycerol = CMP + a phosphatidylcholine.
4143	diacylglycerol kinase activity	F	Catalysis of the reaction: NTP + 1,2-diacylglycerol = NDP + 1,2-diacylglycerol-3-phosphate.
4144	diacylglycerol O-acyltransferase activity	F	Catalysis of the reaction: acyl-CoA + 1,2-diacylglycerol = CoA + triacylglycerol.
4145	diamine N-acetyltransferase activity	F	Catalysis of the reaction: acetyl-CoA + an alkane-alpha,omega-diamine = CoA + an N-acetyldiamine.
4146	dihydrofolate reductase activity	F	Catalysis of the reaction: 5,6,7,8-tetrahydrofolate + NADP+ = 7,8-dihydrofolate + NADPH + H+.
4147	dihydrolipoamide branched chain acyltransferase activity	F	Catalysis of the reaction: acyl-CoA + dihydrolipoamide = CoA + S-acyldihydrolipoamide, where the acyl group is a branched chain.
4148	dihydrolipoyl dehydrogenase activity	F	Catalysis of the reaction: protein N6-(dihydrolipoyl)lysine + NAD+ = protein N6-(lipoyl)lysine + NADH + H+.
4149	dihydrolipoyllysine-residue succinyltransferase activity	F	Catalysis of the reaction: succinyl-CoA + dihydrolipoamide = CoA + S-succinyldihydrolipoamide.
4150	dihydroneopterin aldolase activity	F	Catalysis of the reaction: 2-amino-4-hydroxy-6-(D-erythro-1,2,3-trihydroxypropyl)-7,8-dihydropteridine = 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine + glycolaldehyde.
4151	dihydroorotase activity	F	Catalysis of the reaction: (S)-dihydroorotate + H(2)O = N-carbamoyl-L-aspartate + H(+).
4152	dihydroorotate dehydrogenase activity	F	Catalysis of the reaction: (S)-dihydroorotate + A = AH(2) + orotate.
4153	dihydropterin deaminase activity	F	Catalysis of the reaction: 7,8-dihydropterin + H2O = 7,8-dihydrolumazine + NH3.
4154	dihydropterin oxidase activity	F	Catalysis of the reaction: a 7,8-dihydropteridine + O2 = a pterin + hydrogen peroxide.
4155	6,7-dihydropteridine reductase activity	F	Catalysis of the reaction: NADP+ + 5,6,7,8-tetrahydropteridine = NADPH + H+ + 6,7-dihydropteridine.
4156	dihydropteroate synthase activity	F	Catalysis of the reaction: 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate + 4-aminobenzoate = diphosphate + dihydropteroate.
4157	dihydropyrimidinase activity	F	Catalysis of the reaction: 5,6-dihydrouracil + H2O = 3-ureidopropionate.
4158	dihydroorotate oxidase activity	F	Catalysis of the reaction: (S)-dihydroorotate + O(2) = H(2)O(2) + orotate.
4159	dihydrouracil dehydrogenase (NAD+) activity	F	Catalysis of the reaction: 5,6-dihydrouracil + NAD+ = uracil + NADH + H+.
4160	dihydroxy-acid dehydratase activity	F	Catalysis of the reaction: 2,3-dihydroxy-3-methylbutanoate = 3-methyl-2-oxobutanoate + H2O.
4161	dimethylallyltranstransferase activity	F	Catalysis of the reaction: dimethylallyl diphosphate + isopentenyl diphosphate = diphosphate + geranyl diphosphate.
4162	dimethylnitrosamine demethylase activity	F	Catalysis of the removal of a methyl group from N-nitrosodimethylamine.
4163	diphosphomevalonate decarboxylase activity	F	Catalysis of the reaction: (R)-5-diphosphomevalonate + ATP = ADP + CO(2) + H(+) + isopentenyl diphosphate + phosphate.
4164	diphthine synthase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + 2-(3-carboxy-3-aminopropyl)-L-histidine = S-adenosyl-L-homocysteine + 2-(3-carboxy-3-(methylammonio)propyl)-L-histidine.
4165	dodecenoyl-CoA delta-isomerase activity	F	Catalysis of the reaction: 3-cis-dodecenoyl-CoA = 2-trans-dodecenoyl-CoA.
4166	dolichyl-phosphate alpha-N-acetylglucosaminyltransferase activity	F	Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + dolichyl phosphate = UDP + dolichyl N-acetyl-alpha-D-glucosaminyl phosphate.
4167	dopachrome isomerase activity	F	Catalysis of the reaction: L-dopachrome = 5,6-dihydroxyindole-2-carboxylate.
4168	dolichol kinase activity	F	Catalysis of the reaction: CTP + dolichol = CDP + dolichyl phosphate.
4169	dolichyl-phosphate-mannose-protein mannosyltransferase activity	F	Catalysis of the reaction: dolichyl phosphate D-mannose + protein = dolichyl phosphate + O-D-mannosylprotein.
4170	dUTP diphosphatase activity	F	Catalysis of the reaction: dUTP + H2O = dUMP + diphosphate.
4173	ecdysone O-acyltransferase activity	F	Catalysis of the reaction: Ecdysone + palmitoyl-CoA = CoA + ecdysone palmitate.
4174	electron-transferring-flavoprotein dehydrogenase activity	F	Catalysis of the reaction: reduced ETF + ubiquinone = ETF + ubiquinol.
4175	endopeptidase activity	F	Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain.
4176	ATP-dependent peptidase activity	F	Catalysis of the reaction: ATP + H2O = ADP + phosphate, to drive the hydrolysis of peptide bonds.
4177	aminopeptidase activity	F	Catalysis of the hydrolysis of N-terminal amino acid residues from in a polypeptide chain.
4180	carboxypeptidase activity	F	Catalysis of the hydrolysis of the terminal or penultimate peptide bond at the C-terminal end of a peptide or polypeptide.
4181	metallocarboxypeptidase activity	F	Catalysis of the hydrolysis of C-terminal amino acid residues from a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions.
4185	serine-type carboxypeptidase activity	F	Catalysis of the hydrolysis of a peptide bond not more than three residues from the C-terminus of a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine).
4190	aspartic-type endopeptidase activity	F	Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which a water molecule bound by the side chains of aspartic residues at the active center acts as a nucleophile.
4197	cysteine-type endopeptidase activity	F	Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile.
4198	calcium-dependent cysteine-type endopeptidase activity	F	Catalysis of the hydrolysis of nonterminal peptide bonds in a polypeptide chain by a mechanism using a cysteine residue at the enzyme active center, and requiring the presence of calcium.
4222	metalloendopeptidase activity	F	Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions.
4252	serine-type endopeptidase activity	F	Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine).
4298	threonine-type endopeptidase activity	F	Catalysis of the hydrolysis of internal peptide bonds in a polypeptide chain by a mechanism in which the hydroxyl group of a threonine residue at the active center acts as a nucleophile.
4300	enoyl-CoA hydratase activity	F	Catalysis of the reaction: (3S)-3-hydroxyacyl-CoA = trans-2-enoyl-CoA + H2O.
4301	epoxide hydrolase activity	F	Catalysis of the reaction: an epoxide + H2O = a glycol.
4303	estradiol 17-beta-dehydrogenase activity	F	Catalysis of the reaction: estradiol-17-beta + NADP+ = estrone + NADPH + H+.
4304	estrone sulfotransferase activity	F	Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + estrone = adenosine 3',5'-bisphosphate + estrone 3-sulfate.
4305	ethanolamine kinase activity	F	Catalysis of the reaction: ATP + ethanolamine = ADP + 2 H(+) + phosphoethanolamine.
4306	ethanolamine-phosphate cytidylyltransferase activity	F	Catalysis of the reaction: CTP + ethanolamine phosphate = diphosphate + CDP-ethanolamine.
4307	ethanolaminephosphotransferase activity	F	Catalysis of the reaction: CDP-ethanolamine + 1,2-diacylglycerol = CMP + a phosphatidylethanolamine.
4308	exo-alpha-sialidase activity	F	Catalysis of the hydrolysis of alpha-(2->3)-, alpha-(2->6)-, alpha-(2->8)-glycosidic linkages of terminal sialic residues in oligosaccharides, glycoproteins, glycolipids, colominic acid and synthetic substrates.
4309	exopolyphosphatase activity	F	Catalysis of the reaction: polyphosphate(n) + H2O = polyphosphate(n-1) + phosphate.
4310	farnesyl-diphosphate farnesyltransferase activity	F	Catalysis of the reaction: 2 farnesyl diphosphate = diphosphate + presqualene diphosphate.
4311	farnesyltranstransferase activity	F	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate + isopentenyl diphosphate = diphosphate + geranylgeranyl diphosphate.
4312	fatty acid synthase activity	F	Catalysis of the reaction: acetyl-CoA + n malonyl-CoA + 2n NADPH + 2n H+ = long-chain fatty acid + n+1 CoA + n CO2 + 2n NADP+.
4313	[acyl-carrier-protein] S-acetyltransferase activity	F	Catalysis of the reaction: acetyl-CoA + [acyl-carrier protein] = CoA + acetyl-[acyl-carrier protein].
4314	[acyl-carrier-protein] S-malonyltransferase activity	F	Catalysis of the reaction: malonyl-CoA + [acyl-carrier protein] = CoA + malonyl-[acyl-carrier protein].
4315	3-oxoacyl-[acyl-carrier-protein] synthase activity	F	Catalysis of the reaction: acyl-[acyl-carrier protein] + malonyl-[acyl-carrier protein] = 3-oxoacyl-[acyl-carrier protein] + CO2 + [acyl-carrier protein].
4316	3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity	F	Catalysis of the reaction: (3R)-3-hydroxyacyl-[acyl-carrier protein] + NADP+ = 3-oxoacyl-[acyl-carrier protein] + NADPH + H+.
4317	3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity	F	Catalysis of the reaction: (3R)-3-hydroxypalmitoyl-[acyl-carrier protein] = 2-hexadecenoyl-[acyl-carrier protein] + H2O.
4318	enoyl-[acyl-carrier-protein] reductase (NADH) activity	F	Catalysis of the reaction: acyl-[acyl-carrier protein] + NAD+ = trans-2,3-dehydroacyl-[acyl-carrier protein] + NADH + H+.
4319	enoyl-[acyl-carrier-protein] reductase (NADPH, B-specific) activity	F	Catalysis of the reaction: acyl-[acyl-carrier protein] + NADP+ = trans-2,3-dehydroacyl-[acyl-carrier protein] + NADPH + H+.
4320	oleoyl-[acyl-carrier-protein] hydrolase activity	F	Catalysis of the reaction: oleoyl-[acyl-carrier protein] + H2O = [acyl-carrier protein] + oleate.
4321	fatty-acyl-CoA synthase activity	F	Catalysis of the reaction: acetyl-CoA + n malonyl-CoA + 2n NADH + 2n NADPH + 4n H+ = a long-chain acyl-CoA + n CoA + n CO2 + 2n NAD+ + 2n NADP+.
4322	ferroxidase activity	F	Catalysis of the reaction: 4 Fe2+ + 4 H+ + O2 = 4 Fe3+ + 2 H2O.
4324	ferredoxin-NADP+ reductase activity	F	Catalysis of the reaction: reduced ferredoxin + NADP+ = oxidized ferredoxin + NADPH + H+.
4325	ferrochelatase activity	F	Catalysis of the reaction: protoheme = Fe(2+) + protoporphyrin IX.
4326	tetrahydrofolylpolyglutamate synthase activity	F	Catalysis of the reaction: ATP + tetrahydrofolyl-(Glu)(n) + L-glutamate = ADP + phosphate + tetrahydrofolyl-(Glu)(n+1).
4328	formamidase activity	F	Catalysis of the reaction: formamide + H(2)O = formate + NH(4)(+).
4329	formate-tetrahydrofolate ligase activity	F	Catalysis of the reaction: ATP + formate + tetrahydrofolate = ADP + phosphate + 10-formyltetrahydrofolate.
4331	fructose-2,6-bisphosphate 2-phosphatase activity	F	Catalysis of the reaction: D-fructose 2,6-bisphosphate + H2O = D-fructose-6-phosphate + phosphate.
4332	fructose-bisphosphate aldolase activity	F	Catalysis of the reaction: D-fructose 1,6-bisphosphate = glycerone phosphate + D-glyceraldehyde-3-phosphate.
4333	fumarate hydratase activity	F	Catalysis of the reaction: (S)-malate = fumarate + H(2)O.
4334	fumarylacetoacetase activity	F	Catalysis of the reaction: 4-fumarylacetoacetate + H(2)O = acetoacetate + fumarate + H(+).
4335	galactokinase activity	F	Catalysis of the reaction: D-galactose + ATP = alpha-D-galactose 1-phosphate + ADP + 2 H(+).
4336	galactosylceramidase activity	F	Catalysis of the reaction: D-galactosyl-N-acylsphingosine + H2O = D-galactose + N-acylsphingosine.
4337	geranyltranstransferase activity	F	Catalysis of the reaction: geranyl diphosphate + isopentenyl diphosphate = 2-trans,6-trans-farnesyl diphosphate + diphosphate.
4338	glucan exo-1,3-beta-glucosidase activity	F	Catalysis of the successive hydrolysis of beta-D-glucose units from the non-reducing ends of (1->3)-beta-D-glucans, releasing alpha-glucose.
4339	glucan 1,4-alpha-glucosidase activity	F	Catalysis of the hydrolysis of terminal (1->4)-linked alpha-D-glucose residues successively from non-reducing ends of the chains with release of beta-D-glucose.
4340	glucokinase activity	F	Catalysis of the reaction: ATP + D-glucose = ADP + D-glucose-6-phosphate.
4341	gluconolactonase activity	F	Catalysis of the reaction: D-glucono-1,5-lactone + H2O = D-gluconate.
4342	glucosamine-6-phosphate deaminase activity	F	Catalysis of the reaction: D-glucosamine 6-phosphate + H(2)O = beta-D-fructose 6-phosphate + NH(4)(+).
4343	glucosamine 6-phosphate N-acetyltransferase activity	F	Catalysis of the reaction: D-glucosamine 6-phosphate + acetyl-CoA = N-acetyl-D-glucosamine 6-phosphate + CoA + H(+).
4344	glucose dehydrogenase activity	F	Catalysis of the reaction: D-glucose + acceptor = D-glucono-1,5-lactone + reduced acceptor.
4345	glucose-6-phosphate dehydrogenase activity	F	Catalysis of the reaction: D-glucose 6-phosphate + NADP+ = D-glucono-1,5-lactone 6-phosphate + NADPH + H+.
4346	glucose-6-phosphatase activity	F	Catalysis of the reaction: D-glucopyranose 6-phosphate + H2O = D-glucose + phosphate. D-glucopyranose is also known as D-glucose 6-phosphate.
4347	glucose-6-phosphate isomerase activity	F	Catalysis of the reaction: D-glucose 6-phosphate = D-fructose 6-phosphate.
4348	glucosylceramidase activity	F	Catalysis of the reaction: D-glucosyl-N-acylsphingosine + H2O = D-glucose + N-acylsphingosine.
4349	glutamate 5-kinase activity	F	Catalysis of the reaction: L-glutamate + ATP = L-glutamyl 5-phosphate + ADP + H(+).
4350	glutamate-5-semialdehyde dehydrogenase activity	F	Catalysis of the reaction: L-glutamate 5-semialdehyde + NADP(+) + phosphate = L-glutamyl 5-phosphate + H(+) + NADPH.
4351	glutamate decarboxylase activity	F	Catalysis of the reaction: L-glutamate = 4-aminobutanoate + CO2.
4352	glutamate dehydrogenase (NAD+) activity	F	Catalysis of the reaction: L-glutamate + H2O + NAD+ = 2-oxoglutarate + NH3 + NADH + H+.
4353	glutamate dehydrogenase [NAD(P)+] activity	F	Catalysis of the reaction: L-glutamate + H2O + NAD(P)+ = 2-oxoglutarate + NH3 + NAD(P)H + H+.
4354	glutamate dehydrogenase (NADP+) activity	F	Catalysis of the reaction: L-glutamate + H2O + NADP+ = 2-oxoglutarate + NH3 + NADPH + H+.
4355	glutamate synthase (NADPH) activity	F	Catalysis of the reaction: 2 L-glutamate + NADP(+) = 2-oxoglutarate + L-glutamine + H(+) + NADPH. This is a two-step reaction: (a) L-glutamate + NH3 = L-glutamine + H2O, (b) L-glutamate + NADP+ + H2O = NH3 + 2-oxoglutarate + NADPH + H+.
4356	glutamate-ammonia ligase activity	F	Catalysis of the reaction: L-glutamate + ATP + NH(4)(+) = L-glutamine + ADP + 2 H(+) + phosphate.
4357	glutamate-cysteine ligase activity	F	Catalysis of the reaction: L-cysteine + L-glutamate + ATP = L-gamma-glutamyl-L-cysteine + ADP + 2 H(+) + phosphate.
4358	glutamate N-acetyltransferase activity	F	Catalysis of the reaction: N(2)-acetyl-L-ornithine + L-glutamate = N-acetyl-L-glutamate + L-ornithine.
4359	glutaminase activity	F	Catalysis of the reaction: L-glutamine + H2O = L-glutamate + NH3.
4360	glutamine-fructose-6-phosphate transaminase (isomerizing) activity	F	Catalysis of the reaction: beta-D-fructose 6-phosphate + L-glutamine = D-glucosamine 6-phosphate + L-glutamate.
4361	glutaryl-CoA dehydrogenase activity	F	Catalysis of the reaction: glutaryl-CoA + acceptor = crotonoyl-CoA + CO2 + reduced acceptor.
4362	glutathione-disulfide reductase activity	F	Catalysis of the reaction: 2 glutathione + NADP+ = glutathione disulfide + NADPH + H+.
4363	glutathione synthase activity	F	Catalysis of the reaction: L-gamma-glutamyl-L-cysteine + ATP + glycine = ADP + glutathione + 2 H(+) + phosphate.
4364	glutathione transferase activity	F	Catalysis of the reaction: R-X + glutathione = H-X + R-S-glutathione. R may be an aliphatic, aromatic or heterocyclic group; X may be a sulfate, nitrile or halide group.
4365	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity	F	Catalysis of the reaction: D-glyceraldehyde 3-phosphate + phosphate + NAD+ = 3-phospho-D-glyceroyl phosphate + NADH + H+.
4366	glycerol-3-phosphate O-acyltransferase activity	F	Catalysis of the reaction: acyl-CoA + sn-glycerol 3-phosphate = CoA + 1-acyl-sn-glycerol 3-phosphate.
4367	glycerol-3-phosphate dehydrogenase [NAD+] activity	F	Catalysis of the reaction: sn-glycerol 3-phosphate + NAD+ = glycerone phosphate + NADH + H+.
4368	glycerol-3-phosphate dehydrogenase activity	F	Catalysis of the reaction: sn-glycerol 3-phosphate + a quinone = glycerone phosphate + a quinol.
4369	glycerol-3-phosphate oxidase activity	F	Catalysis of the reaction: sn-glycerol 3-phosphate + O(2) = glycerone phosphate + H(2)O(2).
4370	glycerol kinase activity	F	Catalysis of the reaction: ATP + glycerol = sn-glycerol 3-phosphate + ADP + 2 H(+).
4371	glycerone kinase activity	F	Catalysis of the reaction: ATP + glycerone = ADP + glycerone phosphate + 2 H(+).
4372	glycine hydroxymethyltransferase activity	F	Catalysis of the reaction: 5,10-methylenetetrahydrofolate + glycine + H2O = tetrahydrofolate + L-serine.
4373	glycogen (starch) synthase activity	F	Catalysis of the reaction: UDP-glucose + (1,4)-alpha-D-glucosyl(n) = UDP + (1,4)-alpha-D-glucosyl(n+1).
4375	glycine dehydrogenase (decarboxylating) activity	F	Catalysis of the reaction: glycine + lipoylprotein = S-aminomethyldihydrolipoylprotein + CO2.
4376	glycolipid mannosyltransferase activity	F	Catalysis of the transfer of an alpha-D-mannosyl residue from GDP-mannose into lipid-linked oligosaccharide, forming an alpha-D-mannosyl-D-mannose linkage.
4377	GDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase activity	F	Catalysis of the reaction: an alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc-diphosphodolichol + 2 GDP-alpha-D-mannose = an alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc-diphosphodolichol + 2 GDP + 2 H+. This reaction is the transfer of an alpha-D-mannosyl residue from GDP-mannose into lipid-linked oligosaccharide, forming an alpha-(1->2)-D-mannosyl-D-mannose linkage.
4378	GDP-Man:Man1GlcNAc2-PP-Dol alpha-1,3-mannosyltransferase activity	F	Catalysis of the reaction: beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc-diphosphodolichol + GDP-alpha-D-mannose = alpha-D-Man-(1->3)-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc-diphosphodolichol + GDP + H+. This reaction is the transfer of an alpha-D-mannosyl residue from GDP-mannose into lipid-linked oligosaccharide, forming an alpha-(1->3)-D-mannosyl-D-mannose linkage.
4379	glycylpeptide N-tetradecanoyltransferase activity	F	Catalysis of the reaction: tetradecanoyl-CoA + glycyl-peptide = CoA + N-tetradecanoylglycyl-peptide.
4380	glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase activity	F	Catalysis of the reaction: UDP-N-acetyl-D-galactosamine + glycoprotein-alpha-L-fucosyl-(1,2)-D-galactose = UDP + glycoprotein-N-acetyl-alpha-D-galactosaminyl-(1,3)-(alpha-L-fucosyl-(1,2))-D-galactose.
4381	fucosylgalactoside 3-alpha-galactosyltransferase activity	F	Catalysis of the reaction: UDP-galactose + glycoprotein-alpha-L-fucosyl-(1,2)-D-galactose = UDP + glycoprotein-alpha-D-galactosyl-(1,3)-(alpha-L-fucosyl-(1,2))-D-galactose.
4382	guanosine-diphosphatase activity	F	Catalysis of the reaction: GDP + H2O = GMP + phosphate.
4383	guanylate cyclase activity	F	Catalysis of the reaction: GTP = 3',5'-cyclic GMP + diphosphate.
4385	guanylate kinase activity	F	Catalysis of the reaction: ATP + GMP = ADP + GDP.
4386	helicase activity	F	Catalysis of the reaction: NTP + H2O = NDP + phosphate, to drive the unwinding of a DNA or RNA helix.
4392	heme oxygenase (decyclizing) activity	F	Catalysis of the reaction: heme + 3 donor-H2 + 3 O2 = biliverdin + Fe2+ + CO + 3 acceptor + 3 H2O.
4394	heparan sulfate 2-O-sulfotransferase activity	F	Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + heparan sulfate = adenosine 3',5'-bisphosphate + heparan sulfate 2-O-sulfate; results in 2-O-sulfation of iduronic acid residues in heparan sulfate.
4395	hexaprenyldihydroxybenzoate methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + 3-hexaprenyl-4,5-dihydroxybenzoate = S-adenosyl-L-homocysteine + 3-hexaprenyl-4-hydroxy-5-methoxybenzoate.
4396	hexokinase activity	F	Catalysis of the reaction: ATP + D-hexose = ADP + D-hexose 6-phosphate.
4397	histidine ammonia-lyase activity	F	Catalysis of the reaction: L-histidine = urocanate + NH3.
4398	histidine decarboxylase activity	F	Catalysis of the reaction: L-histidine = histamine + CO2.
4399	histidinol dehydrogenase activity	F	Catalysis of the reaction: L-histidinol + NAD+ = L-histidine + NADH + H+.
4400	histidinol-phosphate transaminase activity	F	Catalysis of the reaction: L-histidinol-phosphate + 2-oxoglutarate = 3-(imidazol-4-yl)-2-oxopropyl phosphate + L-glutamate.
4401	histidinol-phosphatase activity	F	Catalysis of the reaction: L-histidinol phosphate + H(2)O = L-histidinol + phosphate.
4402	histone acetyltransferase activity	F	Catalysis of the reaction: acetyl-CoA + histone = CoA + acetyl-histone.
4407	histone deacetylase activity	F	Catalysis of the reaction: histone N6-acetyl-L-lysine + H2O = histone L-lysine + acetate. This reaction represents the removal of an acetyl group from a histone, a class of proteins complexed to DNA in chromatin and chromosomes.
4408	holocytochrome-c synthase activity	F	Catalysis of the reaction: holocytochrome c = apocytochrome c + heme.
4409	homoaconitate hydratase activity	F	Catalysis of the reaction: (-)-homoisocitrate = cis-homoaconitate + H(2)O.
4410	homocitrate synthase activity	F	Catalysis of the reaction: 2-oxoglutarate + acetyl-CoA + H(2)O = CoA + H(+) + homocitrate.
4411	homogentisate 1,2-dioxygenase activity	F	Catalysis of the reaction: homogentisate + O(2) = 4-maleylacetoacetate + H(+).
4412	homoserine dehydrogenase activity	F	Catalysis of the reaction: L-homoserine + NADP+ = L-aspartate-4-semialdehyde + NADPH + H+.
4413	homoserine kinase activity	F	Catalysis of the reaction: L-homoserine + ATP = O-phospho-L-homoserine + ADP + 2 H(+).
4414	homoserine O-acetyltransferase activity	F	Catalysis of the reaction: L-homoserine + acetyl-CoA = O-acetyl-L-homoserine + CoA.
4415	hyalurononglucosaminidase activity	F	Catalysis of the random hydrolysis of (1->4) linkages between N-acetyl-beta-D-glucosamine and D-glucuronate residues in hyaluronate.
4416	hydroxyacylglutathione hydrolase activity	F	Catalysis of the reaction: (S)-(2-hydroxyacyl)glutathione + H2O = glutathione + a 2-hydroxy carboxylate.
4417	hydroxyethylthiazole kinase activity	F	Catalysis of the reaction: 5-(2-hydroxyethyl)-4-methylthiazole + ATP = 4-methyl-5-(2-phosphoethyl)-thiazole + ADP + 2 H(+).
4418	hydroxymethylbilane synthase activity	F	Catalysis of the reaction: H(2)O + 4 porphobilinogen = hydroxymethylbilane + 4 NH(4)(+).
4419	hydroxymethylglutaryl-CoA lyase activity	F	Catalysis of the reaction: (S)-3-hydroxy-3-methylglutaryl-CoA = acetoacetate + acetyl-CoA.
4420	hydroxymethylglutaryl-CoA reductase (NADPH) activity	F	Catalysis of the reaction: (R)-mevalonate + CoA + 2 NADP(+) = (S)-3-hydroxy-3-methylglutaryl-CoA + 2 H(+) + 2 NADPH.
4421	hydroxymethylglutaryl-CoA synthase activity	F	Catalysis of the reaction: acetoacetyl-CoA + acetyl-CoA + H(2)O = (S)-3-hydroxy-3-methylglutaryl-CoA + CoA + H(+).
4422	hypoxanthine phosphoribosyltransferase activity	F	Catalysis of the reaction: IMP + diphosphate = hypoxanthine + 5-phospho-alpha-D-ribose 1-diphosphate.
4423	iduronate-2-sulfatase activity	F	Catalysis of the hydrolysis of the 2-sulfate groups of the L-iduronate 2-sulfate units of dermatan sulfate, heparan sulfate and heparin.
4424	imidazoleglycerol-phosphate dehydratase activity	F	Catalysis of the reaction: D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate = 3-(imidazol-4-yl)-2-oxopropyl phosphate + H(2)O.
4425	indole-3-glycerol-phosphate synthase activity	F	Catalysis of the reaction: 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate = 1-(indol-3-yl)glycerol 3-phosphate + CO2 + H2O.
4427	inorganic diphosphatase activity	F	Catalysis of the reaction: diphosphate + H(2)O = H(+) + 2 phosphate.
4430	1-phosphatidylinositol 4-kinase activity	F	Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol + ATP = 1-phosphatidyl-1D-myo-inositol 4-phosphate + ADP + 2 H(+).
4435	phosphatidylinositol phospholipase C activity	F	Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H(2)O = 1,2-diacylglycerol + 1D-myo-inositol 1,4,5-trisphosphate + H(+).
4436	phosphatidylinositol diacylglycerol-lyase activity	F	Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol = D-myo-inositol 1,2-cyclic phosphate + diacylglycerol.
4438	phosphatidylinositol-3-phosphatase activity	F	Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 3-phosphate + H2O = 1-phosphatidyl-1D-myo-inositol + phosphate.
4439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity	F	Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H(2)O = 1-phosphatidyl-1D-myo-inositol 4-phosphate + phosphate.
4441	inositol-1,4-bisphosphate 1-phosphatase activity	F	Catalysis of the reaction: 1D-myo-inositol 1,4-bisphosphate + H2O = 1D-myo-inositol 4-phosphate + phosphate.
4445	inositol-polyphosphate 5-phosphatase activity	F	Catalysis of the reactions: D-myo-inositol 1,4,5-trisphosphate + H2O = myo-inositol 1,4-bisphosphate + phosphate, and 1D-myo-inositol 1,3,4,5-tetrakisphosphate + H2O = 1D-myo-inositol 1,3,4-trisphosphate + phosphate.
4446	inositol-hexakisphosphate phosphatase activity	F	Catalysis of the reaction: myo-inositol hexakisphosphate + H2O = myo-inositol pentakisphosphate (mixed isomers) + phosphate.
4447	iodide peroxidase activity	F	Catalysis of the reaction: iodide + hydrogen peroxide = iodine + 2 H2O.
4448	isocitrate dehydrogenase activity	F	Catalysis of the reaction: isocitrate + acceptor = 2-oxoglutarate + CO2 + reduced acceptor.
4449	isocitrate dehydrogenase (NAD+) activity	F	Catalysis of the reaction: isocitrate + NAD+ = 2-oxoglutarate + CO2 + NADH + H+.
4450	isocitrate dehydrogenase (NADP+) activity	F	Catalysis of the reaction: isocitrate + NADP+ = 2-oxoglutarate + CO2 + NADPH + H+.
4451	isocitrate lyase activity	F	Catalysis of the reaction: isocitrate = glyoxylate + succinate.
4452	isopentenyl-diphosphate delta-isomerase activity	F	Catalysis of the reaction: isopentenyl diphosphate = dimethylallyl diphosphate.
4453	juvenile-hormone esterase activity	F	Catalysis of the reaction: methyl (2E,6E)-(10R,11S)-10,11-epoxy-3,7,11-trimethyltrideca-2,6-dienoate + H2O = (2E,6E)-(10R,11S)-10,11-epoxy-3,7,11-trimethyltrideca-2,6-dienoate + methanol. A carboxylesterase that hydrolyzes the ester linkage of juvenile hormone.
4454	ketohexokinase activity	F	Catalysis of the reaction: ATP + D-fructose = ADP + D-fructose 1-phosphate.
4455	ketol-acid reductoisomerase activity	F	Catalysis of the reaction: (R)-2,3-dihydroxy-3-methylbutanoate + NADP+ = (S)-2-hydroxy-2-methyl-3-oxobutanoate + NADPH + H+.
4456	phosphogluconate dehydratase activity	F	Catalysis of the reaction: 6-phospho-D-gluconate = 2-dehydro-3-deoxy-6-phospho-D-gluconate + H(2)O.
4457	lactate dehydrogenase activity	F	Catalysis of the reaction: lactate + NAD+ = H+ + NADH + pyruvate.
4458	D-lactate dehydrogenase (cytochrome) activity	F	Catalysis of the reaction: (R)-lactate + 2 ferricytochrome c = pyruvate + 2 ferrocytochrome c.
4459	L-lactate dehydrogenase activity	F	Catalysis of the reaction: (S)-lactate + NAD+ = pyruvate + NADH + H+.
4460	L-lactate dehydrogenase (cytochrome) activity	F	Catalysis of the reaction: (S)-lactate + 2 ferricytochrome c = pyruvate + 2 ferrocytochrome c.
4461	lactose synthase activity	F	Catalysis of the reaction: UDP-galactose + D-glucose = UDP + lactose.
4462	lactoylglutathione lyase activity	F	Catalysis of the reaction: (R)-S-lactoylglutathione = glutathione + methylglyoxal.
4463	leukotriene-A4 hydrolase activity	F	Catalysis of the reaction: H(2)O + leukotriene A(4) = leukotriene B(4).
4464	leukotriene-C4 synthase activity	F	Catalysis of the reaction: leukotriene C(4) = glutathione + leukotriene A(4).
4465	lipoprotein lipase activity	F	Catalysis of the reaction: triacylglycerol + H2O = diacylglycerol + a carboxylate, where the triacylglycerol is part of a lipoprotein.
4466	long-chain-acyl-CoA dehydrogenase activity	F	Catalysis of the reaction: acyl-CoA + ETF = 2,3-dehydroacyl-CoA + reduced ETF.
4467	long-chain fatty acid-CoA ligase activity	F	Catalysis of the reaction: ATP + a long-chain fatty acid + CoA = AMP + diphosphate + an acyl-CoA; a long-chain fatty acid is a fatty acid with a chain length between C13 and C22.
4468	lysine N-acetyltransferase activity, acting on acetyl phosphate as donor	F	Catalysis of the reaction: acetyl phosphate + L-lysine = phosphate + N6-acetyl-L-lysine.
4470	malic enzyme activity	F	Catalysis of the oxidative decarboxylation of malate with the concomitant production of pyruvate.
4471	malate dehydrogenase (decarboxylating) (NAD+) activity	F	Catalysis of the reaction: (S)-malate + NAD+ = pyruvate + CO2 + NADH + H+.
4473	malate dehydrogenase (decarboxylating) (NADP+) activity	F	Catalysis of the reaction: (S)-malate + NADP+ = pyruvate + CO2 + NADPH + H+.
4474	malate synthase activity	F	Catalysis of the reaction: acetyl-CoA + glyoxylate + H(2)O = (S)-malate + CoA + H(+).
4475	mannose-1-phosphate guanylyltransferase activity	F	Catalysis of the reaction: alpha-D-mannose 1-phosphate + GTP = diphosphate + GDP-alpha-D-mannose.
4476	mannose-6-phosphate isomerase activity	F	Catalysis of the reaction: D-mannose 6-phosphate = D-fructose 6-phosphate.
4477	methenyltetrahydrofolate cyclohydrolase activity	F	Catalysis of the reaction: 5,10-methenyltetrahydrofolate + H2O = 10-formyltetrahydrofolate.
4478	methionine adenosyltransferase activity	F	Catalysis of the reaction: ATP + L-methionine + H2O = phosphate + diphosphate + S-adenosyl-L-methionine.
4479	methionyl-tRNA formyltransferase activity	F	Catalysis of the reaction: 10-formyltetrahydrofolate + L-methionyl-tRNA + H2O = tetrahydrofolate + N-formylmethionyl-tRNA.
4481	methylene-fatty-acyl-phospholipid synthase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + phospholipid olefinic fatty acid = S-adenosyl-L-homocysteine + phospholipid methylene fatty acid.
4482	mRNA (guanine-N7-)-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + G(5')pppR-RNA = S-adenosyl-L-homocysteine + m7G(5')pppR-RNA. m7G(5')pppR-RNA is mRNA containing an N7-methylguanine cap; R may be guanosine or adenosine.
4483	mRNA (nucleoside-2'-O-)-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + m7G(5')pppR-RNA = S-adenosyl-L-homocysteine + m7G(5')pppRm-RNA. R may be guanosine or adenosine.
4484	mRNA guanylyltransferase activity	F	Catalysis of the reaction: GTP + (5')pp-Pur-mRNA = diphosphate + G(5')ppp-Pur-mRNA; G(5')ppp-Pur-mRNA is mRNA containing a guanosine residue linked 5' through three phosphates to the 5' position of the terminal residue.
4485	methylcrotonoyl-CoA carboxylase activity	F	Catalysis of the reaction: 3-methylbut-2-enoyl-CoA + ATP + bicarbonate = trans-3-methylglutaconyl-CoA + ADP + 2 H(+) + phosphate.
4486	methylenetetrahydrofolate dehydrogenase [NAD(P)+] activity	F	Catalysis of the reaction: 5,10-methylenetetrahydrofolate + NAD(P)+ = 5,10-methenyltetrahydrofolate + NAD(P)H + H+.
4487	methylenetetrahydrofolate dehydrogenase (NAD+) activity	F	Catalysis of the reaction: 5,10-methylenetetrahydrofolate + NAD(+) = 5,10-methenyltetrahydrofolate + NADH.
4488	methylenetetrahydrofolate dehydrogenase (NADP+) activity	F	Catalysis of the reaction: 5,10-methylenetetrahydrofolate + NADP(+) = 5,10-methenyltetrahydrofolate + NADPH.
4489	methylenetetrahydrofolate reductase (NAD(P)H) activity	F	Catalysis of the reaction: 5-methyltetrahydrofolate + NAD(P)+ = 5,10-methylenetetrahydrofolate + NAD(P)H + H+.
4490	methylglutaconyl-CoA hydratase activity	F	Catalysis of the reaction: (S)-3-hydroxy-3-methylglutaryl-CoA = trans-3-methylglutaconyl-CoA + H(2)O.
4491	methylmalonate-semialdehyde dehydrogenase (acylating) activity	F	Catalysis of the reaction: 2-methyl-3-oxopropanoate + CoA + NAD+ = propanoyl-CoA + CO2 + NADH + H+.
4492	methylmalonyl-CoA decarboxylase activity	F	Catalysis of the reaction: (S)-2-methyl-3-oxopropanoyl-CoA = propanoyl-CoA + CO2.
4493	methylmalonyl-CoA epimerase activity	F	Catalysis of the reaction: (R)-methylmalonyl-CoA = (S)-methylmalonyl-CoA.
4494	methylmalonyl-CoA mutase activity	F	Catalysis of the reaction: (R)-methylmalonyl-CoA = succinyl-CoA.
4495	mevaldate reductase activity	F	Catalysis of the reaction: (R)-mevalonate + acceptor = mevaldate + reduced acceptor.
4496	mevalonate kinase activity	F	Catalysis of the reaction: (R)-mevalonate + ATP = (R)-5-phosphomevalonate + ADP + 2 H(+).
4497	monooxygenase activity	F	Catalysis of the incorporation of one atom from molecular oxygen into a compound and the reduction of the other atom of oxygen to water.
4498	calcidiol 1-monooxygenase activity	F	Catalysis of the reaction: calcidiol + H(+) + NADPH + O(2) = calcitriol + H(2)O + NADP(+).
4499	N,N-dimethylaniline monooxygenase activity	F	Catalysis of the reaction: N,N-dimethylaniline + NADPH + H+ + O2 = N,N-dimethylaniline N-oxide + NADP+ + H2O.
4500	dopamine beta-monooxygenase activity	F	Catalysis of the reaction: L-ascorbate + dopamine + O(2) = (R)-noradrenaline + dehydroascorbate + H(2)O.
4501	ecdysone 20-monooxygenase activity	F	Catalysis of the reaction: AH(2) + Ecdysone + O(2) = 20-hydroxyecdysone + A + H(2)O.
4502	kynurenine 3-monooxygenase activity	F	Catalysis of the reaction: L-kynurenine + H(+) + NADPH + O(2) = 3-hydroxy-L-kynurenine + H(2)O + NADP(+).
4503	monophenol monooxygenase activity	F	Catalysis of the reaction: L-tyrosine + L-DOPA + O2 = L-DOPA + DOPAquinone + H2O.
4504	peptidylglycine monooxygenase activity	F	Catalysis of the reaction: peptidyl-glycine + ascorbate + O2 = peptidyl(2-hydroxyglycine) + dehydroascorbate + H2O.
4505	phenylalanine 4-monooxygenase activity	F	Catalysis of the reaction: L-phenylalanine + tetrahydrobiopterin + O2 = L-tyrosine + 4-alpha-hydroxytetrahydrobiopterin.
4506	squalene monooxygenase activity	F	Catalysis of the reaction: H(+) + NADPH + O(2) + squalene = (S)-2,3-epoxysqualene + H(2)O + NADP(+).
4507	steroid 11-beta-monooxygenase activity	F	Catalysis of the reaction: a steroid + reduced adrenal ferredoxin + O2 = an 11-beta-hydroxysteroid + oxidized adrenal ferredoxin + H2O.
4508	steroid 17-alpha-monooxygenase activity	F	Catalysis of the reaction: a steroid + AH2 + O2 = a 17a-hydroxysteroid + A + H2O.
4509	steroid 21-monooxygenase activity	F	Catalysis of the reaction: a steroid + donor-H2 + O2 = a 21-hydroxysteroid + acceptor + H2O.
4510	tryptophan 5-monooxygenase activity	F	Catalysis of the reaction: L-tryptophan + tetrahydrobiopterin + O2 = 5-hydroxy-L-tryptophan + 4-alpha-hydroxytetrahydrobiopterin + H2O.
4511	tyrosine 3-monooxygenase activity	F	Catalysis of the reaction: L-tyrosine + tetrahydrobiopterin + O2 = 3,4-dihydroxy-L-phenylalanine + 4-alpha-hydroxytetrahydrobiopterin + H2O.
4512	inositol-3-phosphate synthase activity	F	Catalysis of the reaction: D-glucose 6-phosphate = 1D-myo-inositol 3-phosphate. This reaction requires NAD, which dehydrogenates the CHOH group to CO at C-5 of the glucose 6-phosphate, making C-6 into an active methylene, able to condense with the aldehyde at C-1. Finally, the enzyme-bound NADH reconverts C-5 into the CHOH form.
4513	neolactotetraosylceramide alpha-2,3-sialyltransferase activity	F	Catalysis of the reaction: CMP-N-acetylneuraminate + beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-beta-D-glucosylceramide = CMP + alpha-N-acetylneuraminyl-2,3-beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-D-glucosylceramide.
4514	nicotinate-nucleotide diphosphorylase (carboxylating) activity	F	Catalysis of the reaction: CO(2) + diphosphate + nicotinate D-ribonucleotide = 5-phospho-alpha-D-ribose 1-diphosphate + 2 H(+) + quinolinate.
4515	nicotinate-nucleotide adenylyltransferase activity	F	Catalysis of the reaction: ATP + nicotinate ribonucleotide = diphosphate + deamido-NAD+.
4516	nicotinate phosphoribosyltransferase activity	F	Catalysis of the reaction: diphosphate + nicotinate D-ribonucleotide = 5-phospho-alpha-D-ribose 1-diphosphate + H(+) + nicotinate.
4517	nitric-oxide synthase activity	F	Catalysis of the reaction: L-arginine + n NADPH + n H+ + m O2 = citrulline + nitric oxide + n NADP+.
4518	nuclease activity	F	Catalysis of the hydrolysis of ester linkages within nucleic acids.
4519	endonuclease activity	F	Catalysis of the hydrolysis of ester linkages within nucleic acids by creating internal breaks.
4520	endodeoxyribonuclease activity	F	Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acid by creating internal breaks.
4521	endoribonuclease activity	F	Catalysis of the hydrolysis of ester linkages within ribonucleic acid by creating internal breaks.
4522	ribonuclease A activity	F	Catalysis of the endonucleolytic cleavage of RNA to 3'-phosphomononucleotides and 3'-phosphooligonucleotides ending in C-P or U-P with 2',3'-cyclic phosphate intermediates.
4523	RNA-DNA hybrid ribonuclease activity	F	Catalysis of the endonucleolytic cleavage of RNA in RNA-DNA hybrids to 5'-phosphomonoesters.
4525	ribonuclease III activity	F	Catalysis of the endonucleolytic cleavage of RNA with 5'-phosphomonoesters and 3'-OH termini; makes two staggered cuts in both strands of dsRNA, leaving a 3' overhang of 2 nt.
4526	ribonuclease P activity	F	Catalysis of the endonucleolytic cleavage of RNA, removing 5' extra nucleotides from tRNA precursor.
4527	exonuclease activity	F	Catalysis of the hydrolysis of ester linkages within nucleic acids by removing nucleotide residues from the 3' or 5' end.
4528	phosphodiesterase I activity	F	Catalysis of the sequential hydrolytic removal of 5'-nucleotides from the 3'-hydroxy termini of 3'-hydroxy-terminated oligonucleotides.
4529	exodeoxyribonuclease activity	F	Catalysis of the sequential cleavage of mononucleotides from a free 5' or 3' terminus of a DNA molecule.
4530	deoxyribonuclease I activity	F	Catalysis of the endonucleolytic cleavage of DNA to 5'-phosphodinucleotide and 5'-phosphooligonucleotide end products.
4531	deoxyribonuclease II activity	F	Catalysis of the endonucleolytic cleavage of DNA to 3'-phosphodinucleotide and 3'-phosphooligonucleotide end products.
4532	exoribonuclease activity	F	Catalysis of the sequential cleavage of mononucleotides from a free 5' or 3' terminus of an RNA molecule.
4533	exoribonuclease H activity	F	Catalysis of the exonucleolytic cleavage of RNA to 5'-phosphomonoester oligonucleotides in both 5' to 3' and 3' to 5' directions.
4534	5'-3' exoribonuclease activity	F	Catalysis of the sequential cleavage of mononucleotides from a free 5' terminus of an RNA molecule.
4535	poly(A)-specific ribonuclease activity	F	Catalysis of the exonucleolytic cleavage of poly(A) to 5'-AMP.
4536	deoxyribonuclease activity	F	Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acid.
4540	ribonuclease activity	F	Catalysis of the hydrolysis of phosphodiester bonds in chains of RNA.
4549	tRNA-specific ribonuclease activity	F	Catalysis of the hydrolysis of phosphodiester bonds in tRNA molecules.
4550	nucleoside diphosphate kinase activity	F	Catalysis of the reaction: ATP + nucleoside diphosphate = ADP + nucleoside triphosphate.
4551	nucleotide diphosphatase activity	F	Catalysis of the reaction: a dinucleotide + H2O = 2 mononucleotides.
4552	octanol dehydrogenase activity	F	Catalysis of the reaction: 1-octanol + NAD(+) = 1-octanal + H(+) + NADH.
4553	hydrolase activity, hydrolyzing O-glycosyl compounds	F	Catalysis of the hydrolysis of any O-glycosyl bond.
4555	alpha,alpha-trehalase activity	F	Catalysis of the reaction: alpha,alpha-trehalose + H2O = 2 D-glucose.
4556	alpha-amylase activity	F	Catalysis of the endohydrolysis of (1->4)-alpha-D-glucosidic linkages in polysaccharides containing three or more alpha-(1->4)-linked D-glucose units.
4557	alpha-galactosidase activity	F	Catalysis of the hydrolysis of terminal, non-reducing alpha-D-galactose residues in alpha-D-galactosides, including galactose oligosaccharides, galactomannans and galactohydrolase.
4558	alpha-1,4-glucosidase activity	F	Catalysis of the hydrolysis of terminal, non-reducing alpha-(1->4)-linked alpha-D-glucose residues with release of alpha-D-glucose.
4559	alpha-mannosidase activity	F	Catalysis of the hydrolysis of terminal, non-reducing alpha-D-mannose residues in alpha-D-mannosides.
4560	alpha-L-fucosidase activity	F	Catalysis of the reaction: an alpha-L-fucoside + H2O = an alcohol + L-fucose.
4561	alpha-N-acetylglucosaminidase activity	F	Catalysis of the hydrolysis of terminal non-reducing N-acetyl-D-glucosamine residues in N-acetyl-alpha-D-glucosaminides.
4563	beta-N-acetylhexosaminidase activity	F	Catalysis of the hydrolysis of terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides.
4564	beta-fructofuranosidase activity	F	Catalysis of the reaction: a fructofuranosylated fructofuranosyl acceptor + H2O = a non fructofuranosylated fructofuranosyl acceptor + a beta-D-fructofuranoside.
4565	beta-galactosidase activity	F	Catalysis of the hydrolysis of terminal, non-reducing beta-D-galactose residues in beta-D-galactosides.
4566	beta-glucuronidase activity	F	Catalysis of the reaction: a beta-D-glucuronoside + H2O = an alcohol + D-glucuronate.
4567	beta-mannosidase activity	F	Catalysis of the hydrolysis of terminal, non-reducing beta-D-mannose residues in beta-D-mannosides.
4568	chitinase activity	F	Catalysis of the hydrolysis of (1->4)-beta linkages of N-acetyl-D-glucosamine (GlcNAc) polymers of chitin and chitodextrins.
4569	glycoprotein endo-alpha-1,2-mannosidase activity	F	Catalysis of the hydrolysis of the terminal alpha-glucosyl-(1,3)-mannosyl unit from Glc-Man(9)-(GlcNAc)(2) oligosaccharide component of the glycoprotein produced in the Golgi membrane.
4571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity	F	Catalysis of the hydrolysis of the terminal (1->2)-linked alpha-D-mannose residues in an oligo-mannose oligosaccharide.
4572	mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity	F	Catalysis of the hydrolysis of the terminal (1->3)- and (1->6)-linked alpha-D-mannose residues in the mannosyl-oligosaccharide Man(5)(GlcNAc)(3).
4573	mannosyl-oligosaccharide glucosidase activity	F	Catalysis of the exohydrolysis of the non-reducing terminal glucose residue in the mannosyl-oligosaccharide Glc(3)Man(9)GlcNAc(2).
4574	oligo-1,6-glucosidase activity	F	Catalysis of the hydrolysis of (1->6)-alpha-D-glucosidic linkages in some oligosaccharides produced from starch and glycogen by alpha-amylase, and in isomaltose. Releases a free alpha-D-glucose.
4575	sucrose alpha-glucosidase activity	F	Catalysis of the reaction: sucrose + H2O = alpha-D-glucose + beta-D-fructose.
4576	oligosaccharyl transferase activity	F	Catalysis of the transfer of a oligosaccharyl group to an acceptor molecule, typically another carbohydrate or a lipid.
4577	N-acetylglucosaminyldiphosphodolichol N-acetylglucosaminyltransferase activity	F	Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + N-acetyl-D-glucosaminyl-diphosphodolichol = UDP + N,N''-diacetylchitobiosyldiphosphodolichol.
4578	chitobiosyldiphosphodolichol beta-mannosyltransferase activity	F	Catalysis of the reaction: GDP-mannose + chitobiosyldiphosphodolichol = GDP + beta-D-mannosylchitobiosyldiphosphodolichol.
4579	dolichyl-diphosphooligosaccharide-protein glycotransferase activity	F	Catalysis of the reaction: dolichyl diphosphooligosaccharide + protein L-asparagine = dolichyl diphosphate + a glycoprotein with the oligosaccharide chain attached by glycosylamine linkage to protein L-asparagine.
4581	dolichyl-phosphate beta-glucosyltransferase activity	F	Catalysis of the reaction: UDP-glucose + dolichyl phosphate = UDP + dolichyl beta-D-glucosyl phosphate.
4582	dolichyl-phosphate beta-D-mannosyltransferase activity	F	Catalysis of the reaction: GDP-mannose + dolichyl phosphate = GDP + dolichyl D-mannosyl phosphate.
4583	dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity	F	Catalysis of the transfer of an alpha-D-glucosyl residue from dolichyl-phosphate D-glucose into a membrane lipid-linked oligosaccharide.
4584	dolichyl-phosphate-mannose-glycolipid alpha-mannosyltransferase activity	F	Catalysis of the transfer of an alpha-D-mannosyl residue from dolichyl-phosphate D-mannose into membrane lipid-linked oligosaccharide.
4585	ornithine carbamoyltransferase activity	F	Catalysis of the reaction: carbamoyl phosphate + L-ornithine = phosphate + L-citrulline.
4586	ornithine decarboxylase activity	F	Catalysis of the reaction: L-ornithine + H(+) = CO(2) + putrescine.
4587	ornithine-oxo-acid transaminase activity	F	Catalysis of the reaction: L-ornithine + a 2-oxo acid = L-glutamate 5-semialdehyde + an L-amino acid.
4588	orotate phosphoribosyltransferase activity	F	Catalysis of the reaction: orotidine 5'-phosphate + diphosphate = orotate + 5-phospho-alpha-D-ribose 1-diphosphate.
4589	orotate reductase (NADH) activity	F	Catalysis of the reaction: (S)-dihydroorotate + NAD(+) = H(+) + NADH + orotate.
4590	orotidine-5'-phosphate decarboxylase activity	F	Catalysis of the reaction: H(+) + orotidine 5'-phosphate = CO(2) + UMP.
4591	oxoglutarate dehydrogenase (succinyl-transferring) activity	F	Catalysis of the reaction: 2-oxoglutarate + lipoamide = S-succinyldihydrolipoamide + CO2.
4592	pantoate-beta-alanine ligase activity	F	Catalysis of the reaction: ATP + (R)-pantoate + beta-alanine = AMP + diphosphate + (R)-pantothenate.
4593	pantothenase activity	F	Catalysis of the reaction: (R)-pantothenate + H(2)O = (R)-pantoate + beta-alanine.
4594	pantothenate kinase activity	F	Catalysis of the reaction: ATP + pantothenate = ADP + D-4'-phosphopantothenate.
4595	pantetheine-phosphate adenylyltransferase activity	F	Catalysis of the reaction: ATP + pantetheine 4'-phosphate = 3'-dephospho-CoA + diphosphate.
4596	peptide alpha-N-acetyltransferase activity	F	Catalysis of the reaction: acetyl-CoA + peptide = CoA + N-alpha-acetylpeptide. This reaction is the acetylation of the N-terminal amino acid residue of a peptide or protein.
4597	peptide-aspartate beta-dioxygenase activity	F	Catalysis of the reaction: peptide L-aspartate + 2-oxoglutarate + O2 = peptide 3-hydroxy-L-aspartate + succinate + CO2.
4598	peptidylamidoglycolate lyase activity	F	Catalysis of the reaction: peptidylamidoglycolate = peptidyl amide + glyoxylate.
4601	peroxidase activity	F	Catalysis of the reaction: donor + hydrogen peroxide = oxidized donor + 2 H2O.
4602	glutathione peroxidase activity	F	Catalysis of the reaction: 2 glutathione + hydrogen peroxide = oxidized glutathione + 2 H2O.
4603	phenylethanolamine N-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + phenylethanolamine = S-adenosyl-L-homocysteine + N-methylphenylethanolamine.
4604	phosphoadenylyl-sulfate reductase (thioredoxin) activity	F	Catalysis of the reaction: adenosine 3',5'-diphosphate + H(+) + sulfite + thioredoxin disulfide = 3'-phospho-5'-adenylyl sulfate + thioredoxin. Thioredoxin disulfide is the oxidized form of thioredoxin; 3'-phosphoadenosine 5'-phosphosulfate is also known as PAPS.
4605	phosphatidate cytidylyltransferase activity	F	Catalysis of the reaction: CTP + phosphatidate = diphosphate + CDP-diacylglycerol.
4607	phosphatidylcholine-sterol O-acyltransferase activity	F	Catalysis of the reaction: phosphatidylcholine + a sterol = a sterol ester + 1-acylglycerophosphocholine.
4608	phosphatidylethanolamine N-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + phosphatidylethanolamine = S-adenosyl-L-homocysteine + H(+) + phosphatidyl-N-methylethanolamine.
4609	phosphatidylserine decarboxylase activity	F	Catalysis of the reaction: H(+) + phosphatidyl-L-serine = CO(2) + phosphatidylethanolamine.
4610	phosphoacetylglucosamine mutase activity	F	Catalysis of the reaction: N-acetyl-alpha-D-glucosamine 1-phosphate = N-acetyl-D-glucosamine 6-phosphate.
4611	phosphoenolpyruvate carboxykinase activity	F	Catalysis of the reaction: source of phosphate + oxaloacetate = phosphoenolpyruvate + CO2 + other reaction products.
4612	phosphoenolpyruvate carboxykinase (ATP) activity	F	Catalysis of the reaction: ATP + oxaloacetate = ADP + CO(2) + H(+) + phosphoenolpyruvate.
4613	phosphoenolpyruvate carboxykinase (GTP) activity	F	Catalysis of the reaction: GTP + oxaloacetate = GDP + phosphoenolpyruvate + CO2.
4614	phosphoglucomutase activity	F	Catalysis of the reaction: alpha-D-glucose 1-phosphate = alpha-D-glucose 6-phosphate.
4615	phosphomannomutase activity	F	Catalysis of the reaction: alpha-D-mannose 1-phosphate = D-mannose 6-phosphate.
4616	phosphogluconate dehydrogenase (decarboxylating) activity	F	Catalysis of the reaction: 6-phospho-D-gluconate + NADP+ = D-ribulose 5-phosphate + CO2 + NADPH + H+.
4617	phosphoglycerate dehydrogenase activity	F	Catalysis of the reaction: 3-phosphoglycerate + NAD+ = 3-phosphohydroxypyruvate + NADH + H+.
4618	phosphoglycerate kinase activity	F	Catalysis of the reaction: 3-phospho-D-glycerate + ATP = 3-phospho-D-glyceroyl phosphate + ADP + H(+).
4619	phosphoglycerate mutase activity	F	Catalysis of the reaction: 2-phospho-D-glycerate = 3-phospho-D-glycerate.
4620	phospholipase activity	F	Catalysis of the hydrolysis of a glycerophospholipid.
4621	glycosylphosphatidylinositol phospholipase D activity	F	Catalysis of the reaction: glycoprotein phosphatidylinositol + H2O = phosphatidate + glycoprotein inositol.
4622	lysophospholipase activity	F	Catalysis of the reaction: 2-lysophosphatidylcholine + H2O = glycerophosphocholine + a carboxylate.
4623	phospholipase A2 activity	F	Catalysis of the reaction: phosphatidylcholine + H2O = 1-acylglycerophosphocholine + a carboxylate.
4629	phospholipase C activity	F	Catalysis of the reaction: a phospholipid + H2O = 1,2-diacylglycerol + a phosphatidate.
4630	phospholipase D activity	F	Catalysis of the reaction: a phosphatidylcholine + H2O = choline + a phosphatidate.
4631	phosphomevalonate kinase activity	F	Catalysis of the reaction: (R)-5-phosphomevalonate + ATP = (R)-5-diphosphomevalonate + ADP + H(+).
4632	phosphopantothenate--cysteine ligase activity	F	Catalysis of the reaction: CTP + (R)-4'-phosphopantothenate + L-cysteine = CMP + diphosphate + (R)-4'-phosphopantothenoyl-L-cysteine. Cysteine can be replaced by some of its derivatives.
4633	phosphopantothenoylcysteine decarboxylase activity	F	Catalysis of the reaction: N-[(R)-4-phosphonatopantothenoyl]-L-cysteinate + H(+) = CO(2) + pantetheine 4'-phosphate.
4634	phosphopyruvate hydratase activity	F	Catalysis of the reaction: 2-phospho-D-glycerate = phosphoenolpyruvate + H2O.
4635	phosphoribosyl-AMP cyclohydrolase activity	F	Catalysis of the reaction: 1-(5-phosphonatoribosyl)-5'-AMP + H(2)O = 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide.
4636	phosphoribosyl-ATP diphosphatase activity	F	Catalysis of the reaction: 1-(5-phospho-D-ribosyl)-ATP + H(2)O = 1-(5-phosphonatoribosyl)-5'-AMP + diphosphate + H(+).
4637	phosphoribosylamine-glycine ligase activity	F	Catalysis of the reaction: 5-phospho-D-ribosylamine + ATP + glycine = N(1)-(5-phospho-D-ribosyl)glycinamide + ADP + 2 H(+) + phosphate.
4638	phosphoribosylaminoimidazole carboxylase activity	F	Catalysis of the reaction: 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + 2 H(+) = 5-amino-1-(5-phospho-D-ribosyl)imidazole + CO(2).
4639	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity	F	Catalysis of the reaction: 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + L-aspartate + ATP = (2S)-2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate + ADP + 2 H(+) + phosphate.
4640	phosphoribosylanthranilate isomerase activity	F	Catalysis of the reaction: N-(5-phospho-beta-D-ribosyl)anthranilate = 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate.
4641	phosphoribosylformylglycinamidine cyclo-ligase activity	F	Catalysis of the reaction: 2-(formamido)-N(1)-(5-phospho-D-ribosyl)acetamidine + ATP = 5-amino-1-(5-phospho-D-ribosyl)imidazole + ADP + 2 H(+) + phosphate.
4642	phosphoribosylformylglycinamidine synthase activity	F	Catalysis of the reaction: N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide + L-glutamine + ATP + H(2)O = 2-(formamido)-N(1)-(5-phospho-D-ribosyl)acetamidine + L-glutamate + ADP + 2 H(+) + phosphate.
4643	phosphoribosylaminoimidazolecarboxamide formyltransferase activity	F	Catalysis of the reaction: 10-formyltetrahydrofolate + 5'-phosphoribosyl-5-amino-4-imidazolecarboxamide = tetrahydrofolate + 5'-phosphoribosyl-5-formamido-4-imidazolecarboxamide.
4644	phosphoribosylglycinamide formyltransferase activity	F	Catalysis of the reaction: 10-formyltetrahydrofolate + N1-(5-phospho-D-ribosyl)glycinamide = tetrahydrofolate + N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide.
4645	phosphorylase activity	F	Catalysis of the reaction: 1,4-alpha-D-glucosyl(n) + phosphate = 1,4-alpha-D-glucosyl(n-1) + alpha-D-glucose 1-phosphate. The name should be qualified in each instance by adding the name of the natural substrate, e.g. maltodextrin phosphorylase, starch phosphorylase, glycogen phosphorylase.
4647	phosphoserine phosphatase activity	F	Catalysis of the reaction: L(or D)-O-phosphoserine + H2O = L(or D)-serine + phosphate.
4648	O-phospho-L-serine:2-oxoglutarate aminotransferase activity	F	Catalysis of the reaction: O-phospho-L-serine + 2-oxoglutarate = 3-phosphonooxypyruvate + L-glutamate.
4649	poly(ADP-ribose) glycohydrolase activity	F	Catalysis of the hydrolysis of poly(ADP-ribose) at glycosidic (1''-2') linkage of ribose-ribose bond to produce free ADP-ribose.
4650	polygalacturonase activity	F	Catalysis of the random hydrolysis of (1->4)-alpha-D-galactosiduronic linkages in pectate and other galacturonans.
4651	polynucleotide 5'-phosphatase activity	F	Catalysis of the reaction: 5'-phosphopolynucleotide + H2O = polynucleotide + phosphate.
4652	polynucleotide adenylyltransferase activity	F	Catalysis of the template-independent extension of the 3'- end of an RNA or DNA strand by addition of one adenosine molecule at a time. Cannot initiate a chain 'de novo'. The primer, depending on the source of the enzyme, may be an RNA or DNA fragment, or oligo(A) bearing a 3'-OH terminal group.
4653	polypeptide N-acetylgalactosaminyltransferase activity	F	Catalysis of the reaction: UDP-N-acetyl-D-galactosamine + polypeptide = UDP + N-acetyl-D-galactosaminyl-polypeptide. This reaction is the modification of serine or threonine residues in polypeptide chains by the transfer of a N-acetylgalactose from UDP-N-acetylgalactose to the hydroxyl group of the amino acid; it is the first step in O-glycan biosynthesis.
4654	polyribonucleotide nucleotidyltransferase activity	F	Catalysis of the reaction: RNA(n+1) + phosphate <=> RNA(n) + a nucleoside diphosphate.
4655	porphobilinogen synthase activity	F	Catalysis of the reaction: 2 5-aminolevulinate = 2 H(2)O + H(+) + porphobilinogen.
4656	procollagen-proline 4-dioxygenase activity	F	Catalysis of the reaction: procollagen L-proline + 2-oxoglutarate + O2 = procollagen trans-4-hydroxy-L-proline + succinate + CO2.
4657	proline dehydrogenase activity	F	Catalysis of the reaction: L-proline + acceptor = (S)-1-pyrroline-5-carboxylate + reduced acceptor.
4658	propionyl-CoA carboxylase activity	F	Catalysis of the reaction: ATP + propanoyl-CoA + HCO3- = ADP + phosphate + (S)-methylmalonyl-CoA.
4659	prenyltransferase activity	F	Catalysis of the transfer of a prenyl group from one compound (donor) to another (acceptor).
4660	protein farnesyltransferase activity	F	Catalysis of the reaction: farnesyl diphosphate + protein-cysteine = S-farnesyl protein + diphosphate.
4661	protein geranylgeranyltransferase activity	F	Catalysis of the covalent addition of a geranylgeranyl (20-carbon isoprenoid) group via thioether linkages to a cysteine residue at or near the C terminus of a protein.
4662	CAAX-protein geranylgeranyltransferase activity	F	Catalysis of the reaction: geranylgeranyl diphosphate + protein-cysteine = S-geranylgeranyl-protein + diphosphate. This reaction is the formation of a thioether linkage between the C-1 atom of the geranylgeranyl group and a cysteine residue fourth from the C-terminus of the protein. The protein substrates have the C-terminal sequence CA1A2X, where the terminal residue, X, is preferably leucine and A2 should not be aromatic. Known substrates include most g-subunits of heterotrimeric G proteins and Ras-related GTPases such as members of the Ras and Rac/Rho families.
4663	Rab geranylgeranyltransferase activity	F	Catalysis of the reaction: 2 geranylgeranyl diphosphate + protein-cysteine = 2 S-geranylgeranyl-protein + 2 diphosphate. This reaction is the formation of two thioether linkages between the C-1 atom of the geranylgeranyl groups and two cysteine residues within the terminal sequence motifs XXCC, XCXC or CCXX. Known substrates include Ras-related GTPases of a single family and the Rab family.
4664	prephenate dehydratase activity	F	Catalysis of the reaction: prephenate = phenylpyruvate + H2O + CO2.
4665	prephenate dehydrogenase (NADP+) activity	F	Catalysis of the reaction: NADP(+) + prephenate = (4-hydroxyphenyl)pyruvate + CO(2) + NADPH.
4666	prostaglandin-endoperoxide synthase activity	F	Catalysis of the reaction: arachidonate + donor-H2 + 2 O2 = prostaglandin H2 + acceptor + H2O.
4667	prostaglandin-D synthase activity	F	Catalysis of the reaction: prostaglandin H(2) = prostaglandin D(2).
4668	protein-arginine deiminase activity	F	Catalysis of the reaction: protein L-arginine + H2O = protein L-citrulline + NH3.
4671	protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + protein C-terminal S-farnesyl-L-cysteine = S-adenosyl-L-homocysteine + protein C-terminal S-farnesyl-L-cysteine methyl ester.
4672	protein kinase activity	F	Catalysis of the phosphorylation of an amino acid residue in a protein, usually according to the reaction: a protein + ATP = a phosphoprotein + ADP.
4673	protein histidine kinase activity	F	Catalysis of the reaction: ATP + protein L-histidine = ADP + protein phospho-L-histidine.
4674	protein serine/threonine kinase activity	F	Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.
4675	transmembrane receptor protein serine/threonine kinase activity	F	Combining with a signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: ATP protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.
4676	3-phosphoinositide-dependent protein kinase activity	F	Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein. This reaction requires the presence of a phosphatidylinositol-3-phosphate.
4677	DNA-dependent protein kinase activity	F	Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein. This reaction requires the presence of DNA.
4679	AMP-activated protein kinase activity	F	Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein. This reaction requires the presence of AMP.
4683	calmodulin-dependent protein kinase activity	F	Catalysis of the reactions: ATP + a protein serine = ADP + protein serine phosphate; and ATP + a protein threonine = ADP + protein threonine phosphate. These reactions require the presence of calcium-bound calmodulin.
4686	elongation factor-2 kinase activity	F	Catalysis of the reaction: ATP + [elongation factor 2] = ADP + [elongation factor 2] phosphate.
4687	myosin light chain kinase activity	F	Catalysis of the reaction: ATP + myosin-light-chain = ADP + myosin-light-chain phosphate.
4689	phosphorylase kinase activity	F	Catalysis of the reaction: 4 ATP + 2 phosphorylase b = 4 ADP + phosphorylase a.
4690	cyclic nucleotide-dependent protein kinase activity	F	Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein. This reaction requires the presence of a cyclic nucleotide.
4691	cAMP-dependent protein kinase activity	F	Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein. This reaction requires the presence of cAMP.
4692	cGMP-dependent protein kinase activity	F	Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein. This reaction requires the presence of cGMP.
4693	cyclin-dependent protein serine/threonine kinase activity	F	Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate. This reaction requires the binding of a regulatory cyclin subunit and full activity requires stimulatory phosphorylation by a CDK-activating kinase (CAK).
4694	eukaryotic translation initiation factor 2alpha kinase activity	F	Catalysis of the reaction: ATP + [eukaryotic translation initiation factor 2 alpha subunit] = ADP + [eukaryotic translation initiation factor 2 alpha subunit] phosphate.
4697	protein kinase C activity	F	Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein. This reaction requires diacylglycerol.
4698	calcium-dependent protein kinase C activity	F	Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein. This reaction requires diacylglycerol and calcium.
4699	calcium-independent protein kinase C activity	F	Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein. This reaction requires diacylglycerol but not calcium.
4702	signal transducer, downstream of receptor, with serine/threonine kinase activity	F	Conveys a signal from an upstream receptor or intracellular signal transducer by catalysis of the reaction: ATP protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.
4703	G-protein coupled receptor kinase activity	F	Catalysis of the reaction: ATP + G-protein coupled receptor = ADP + G-protein coupled receptor phosphate.
4704	NF-kappaB-inducing kinase activity	F	Catalysis of the phosphorylation of the alpha or beta subunit of the inhibitor of kappaB kinase complex (IKK).
4705	JUN kinase activity	F	Catalysis of the reaction: JUN + ATP = JUN phosphate + ADP. This reaction is the phosphorylation and activation of members of the JUN family, a gene family that encodes nuclear transcription factors.
4706	JUN kinase kinase kinase activity	F	Catalysis of the reaction: JNKK + ATP = JNKK phosphate + ADP. This reaction is the phosphorylation and activation of JUN kinase kinases (JNKKs).
4707	MAP kinase activity	F	Catalysis of the reaction: protein + ATP = protein phosphate + ADP. This reaction is the phosphorylation of proteins. Mitogen-activated protein kinase; a family of protein kinases that perform a crucial step in relaying signals from the plasma membrane to the nucleus. They are activated by a wide range of proliferation- or differentiation-inducing signals; activation is strong with agonists such as polypeptide growth factors and tumor-promoting phorbol esters, but weak (in most cell backgrounds) by stress stimuli.
4708	MAP kinase kinase activity	F	Catalysis of the concomitant phosphorylation of threonine (T) and tyrosine (Y) residues in a Thr-Glu-Tyr (TEY) thiolester sequence in a MAP kinase (MAPK) substrate.
4709	MAP kinase kinase kinase activity	F	Catalysis of the phosphorylation and activation of a MAP kinase kinase; each MAP kinase kinase can be phosphorylated by any of several MAP kinase kinase kinases.
4711	ribosomal protein S6 kinase activity	F	Catalysis of the reaction: ribosomal protein S6 + ATP = ribosomal protein S6 phosphate + ATP.
4712	protein serine/threonine/tyrosine kinase activity	F	Catalysis of the reactions: ATP + a protein serine = ADP + protein serine phosphate; ATP + a protein threonine = ADP + protein threonine phosphate; and ATP + a protein tyrosine = ADP + protein tyrosine phosphate.
4713	protein tyrosine kinase activity	F	Catalysis of the reaction: ATP + a protein tyrosine = ADP + protein tyrosine phosphate.
4714	transmembrane receptor protein tyrosine kinase activity	F	Combining with a signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: ATP + a protein-L-tyrosine = ADP + a protein-L-tyrosine phosphate.
4715	non-membrane spanning protein tyrosine kinase activity	F	Catalysis of the reaction: ATP + protein L-tyrosine = ADP + protein L-tyrosine phosphate by a non-membrane spanning protein.
4716	signal transducer, downstream of receptor, with protein tyrosine kinase activity	F	Conveys a signal from an upstream receptor or intracellular signal transducer by catalysis of the reaction: ATP + a protein-L-tyrosine = ADP + a protein-L-tyrosine phosphate.
4719	protein-L-isoaspartate (D-aspartate) O-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + protein L-beta-aspartate = S-adenosyl-L-homocysteine + protein L-beta-aspartate methyl ester.
4720	protein-lysine 6-oxidase activity	F	Catalysis of the reaction: peptidyl-L-lysyl-peptide + H2O + O2 = peptidyl-allysyl-peptide + NH3 + hydrogen peroxide.
4721	phosphoprotein phosphatase activity	F	Catalysis of the reaction: a phosphoprotein + H2O = a protein + phosphate. Together with protein kinases, these enzymes control the state of phosphorylation of cell proteins and thereby provide an important mechanism for regulating cellular activity.
4722	protein serine/threonine phosphatase activity	F	Catalysis of the reaction: protein serine phosphate + H2O = protein serine + phosphate, and protein threonine phosphate + H2O = protein threonine + phosphate.
4723	calcium-dependent protein serine/threonine phosphatase activity	F	Catalysis of the reactions: protein serine phosphate + H2O = protein serine + phosphate; and protein threonine phosphate + H2O = protein threonine + phosphate. These reactions require the presence of calcium ions.
4724	magnesium-dependent protein serine/threonine phosphatase activity	F	Catalysis of the reactions: protein serine phosphate + H2O = protein serine + phosphate; and protein threonine phosphate + H2O = protein threonine + phosphate. These reactions require the presence of magnesium.
4725	protein tyrosine phosphatase activity	F	Catalysis of the reaction: protein tyrosine phosphate + H2O = protein tyrosine + phosphate.
4726	non-membrane spanning protein tyrosine phosphatase activity	F	Catalysis of the reaction: non-membrane spanning protein tyrosine phosphate + H2O = non-membrane spanning protein tyrosine + phosphate.
4727	prenylated protein tyrosine phosphatase activity	F	Catalysis of the reaction: prenylated-protein tyrosine phosphate + H2O = prenylated-protein tyrosine + phosphate.
4728	signal transducer, downstream of receptor, with protein tyrosine phosphatase activity	F	Conveys a signal from an upstream receptor or intracellular signal transducer by catalysis of the reaction: protein tyrosine phosphate + H2O = protein tyrosine + phosphate.
4729	oxygen-dependent protoporphyrinogen oxidase activity	F	Catalysis of the reaction: 3 O(2) + protoporphyrinogen IX = 3 H(2)O(2) + protoporphyrin IX.
4730	pseudouridylate synthase activity	F	Catalysis of the reaction: D-ribose 5-phosphate + uracil = H(2)O + pseudouridine 5'-phosphate.
4731	purine-nucleoside phosphorylase activity	F	Catalysis of the reaction: purine nucleoside + phosphate = purine + alpha-D-ribose 1-phosphate.
4732	pyridoxal oxidase activity	F	Catalysis of the reaction: pyridoxal + H2O + O2 = 4-pyridoxate + hydrogen peroxide.
4733	pyridoxamine-phosphate oxidase activity	F	Catalysis of the reaction: pyridoxamine 5'-phosphate + H2O + O2 = pyridoxal 5'-phosphate + NH3 + hydrogen peroxide.
4734	pyrimidodiazepine synthase activity	F	Catalysis of the reaction: a pyrimidodiazepine + oxidized glutathione = 6-pyruvoyltetrahydropterin + 2 glutathione.
4735	pyrroline-5-carboxylate reductase activity	F	Catalysis of the reaction: L-proline + NADP+ = 1-pyrroline-5-carboxylate + NADPH + H+.
4736	pyruvate carboxylase activity	F	Catalysis of the reaction: ATP + bicarbonate + pyruvate = ADP + 2 H(+) + oxaloacetate + phosphate.
4737	pyruvate decarboxylase activity	F	Catalysis of the reaction: a 2-oxo acid = an aldehyde + CO2.
4738	pyruvate dehydrogenase activity	F	Catalysis of the oxidative decarboxylation of pyruvate.
4739	pyruvate dehydrogenase (acetyl-transferring) activity	F	Catalysis of the reaction: pyruvate + lipoamide = S-acetyldihydrolipoamide + CO2.
4740	pyruvate dehydrogenase (acetyl-transferring) kinase activity	F	Catalysis of the reaction: ATP + pyruvate dehydrogenase (acetyl-transferring) = ADP + pyruvate dehydrogenase (acetyl-transferring) phosphate.
4741	[pyruvate dehydrogenase (lipoamide)] phosphatase activity	F	Catalysis of the reaction: [pyruvate dehydrogenase (lipoamide)] phosphate + H2O = [pyruvate dehydrogenase (lipoamide)] + phosphate.
4742	dihydrolipoyllysine-residue acetyltransferase activity	F	Catalysis of the reaction: acetyl-CoA + dihydrolipoamide = CoA + S-acetyldihydrolipoamide.
4743	pyruvate kinase activity	F	Catalysis of the reaction: ATP + pyruvate = ADP + phosphoenolpyruvate.
4744	retinal isomerase activity	F	Catalysis of the reaction: all-trans-retinal = 11-cis-retinal.
4745	retinol dehydrogenase activity	F	Catalysis of the reaction: retinol + NAD+ = retinal + NADH + H+.
4746	riboflavin synthase activity	F	Catalysis of the reaction: 2 6,7-dimethyl-8-(1-D-ribityl)lumazine + H(+) = 5-amino-6-(D-ribitylamino)uracil + riboflavin.
4747	ribokinase activity	F	Catalysis of the reaction: ATP + D-ribose = ADP + D-ribose 5-phosphate.
4748	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor	F	Catalysis of the reaction: 2'-deoxyribonucleoside diphosphate + thioredoxin disulfide + H2O = ribonucleoside diphosphate + thioredoxin. Thioredoxin disulfide is the oxidized form of thioredoxin.
4749	ribose phosphate diphosphokinase activity	F	Catalysis of the reaction: D-ribose 5-phosphate + ATP = 5-phospho-alpha-D-ribose 1-diphosphate + AMP + 2 H(+).
4750	ribulose-phosphate 3-epimerase activity	F	Catalysis of the reaction: D-ribulose 5-phosphate = D-xylulose 5-phosphate.
4751	ribose-5-phosphate isomerase activity	F	Catalysis of the reaction: D-ribose 5-phosphate = D-ribulose 5-phosphate.
4753	saccharopine dehydrogenase activity	F	Catalysis of the cleavage of N6-(L-1,3-dicarboxypropyl)-L-lysine to release an amino acid (lysine or glutamate), with the concomitant reduction of an electron acceptor.
4754	saccharopine dehydrogenase (NAD+, L-lysine-forming) activity	F	Catalysis of the reaction: L-saccharopine + H(2)O + NAD(+) = 2-oxoglutarate + L-lysine + H(+) + NADH.
4755	saccharopine dehydrogenase (NADP+, L-glutamate-forming) activity	F	Catalysis of the reaction: L-saccharopine + H(2)O + NADP(+) = L-allysine + L-glutamate + H(+) + NADPH.
4756	selenide, water dikinase activity	F	Catalysis of the reaction: ATP + H(2)O + hydrogen selenide = AMP + 3 H(+) + phosphate + selenophosphorate.
4757	sepiapterin reductase activity	F	Catalysis of the reaction: 7,8-dihydrobiopterin + NADP+ = sepiapterin + NADPH + H+.
4758	serine C-palmitoyltransferase activity	F	Catalysis of the reaction: L-serine + H(+) + palmitoyl-CoA = 3-dehydrosphinganine + CO(2) + CoA.
4760	serine-pyruvate transaminase activity	F	Catalysis of the reaction: L-serine + pyruvate = 3-hydroxypyruvate + L-alanine.
4764	shikimate 3-dehydrogenase (NADP+) activity	F	Catalysis of the reaction: shikimate + NADP+ = 3-dehydroshikimate + NADPH + H+.
4765	shikimate kinase activity	F	Catalysis of the reaction: ATP + shikimate = 3-phosphoshikimate + ADP + 2 H(+).
4766	spermidine synthase activity	F	Catalysis of the reaction: S-adenosylmethioninamine + putrescine = 5'-methylthioadenosine + spermidine.
4767	sphingomyelin phosphodiesterase activity	F	Catalysis of the reaction: H(2)O + sphingomyelin = ceramide + choline phosphate + H(+).
4768	stearoyl-CoA 9-desaturase activity	F	Catalysis of the reaction: stearoyl-CoA + 2 ferrocytochrome b5 + O2 + 2 H+ = oleoyl-CoA + 2 ferricytochrome b5 + H2O.
4769	steroid delta-isomerase activity	F	Catalysis of the reaction: a 3-oxo-delta(5)-steroid = a 3-oxo-delta(4)-steroid.
4771	sterol esterase activity	F	Catalysis of the reaction: a steryl ester + H2O = a sterol + a fatty acid.
4772	sterol O-acyltransferase activity	F	Catalysis of the reaction: acyl-CoA + a sterol = CoA + a sterol ester.
4773	steryl-sulfatase activity	F	Catalysis of the reaction: 3-beta-hydroxyandrost-5-en-17-one 3-sulfate + H2O = 3-beta-hydroxyandrost-5-en-17-one + sulfate.
4774	succinate-CoA ligase activity	F	Catalysis of the reaction: succinate + CoA + nucleotide triphosphate = nucleotide diphosphate + phosphate + succinyl-CoA.
4775	succinate-CoA ligase (ADP-forming) activity	F	Catalysis of the reaction: ATP + succinate + CoA = ADP + succinyl-CoA + phosphate.
4776	succinate-CoA ligase (GDP-forming) activity	F	Catalysis of the reaction: GTP + succinate + CoA = GDP + succinyl-CoA + phosphate.
4777	succinate-semialdehyde dehydrogenase (NAD+) activity	F	Catalysis of the reaction: succinate semialdehyde + NAD+ + H2O = succinate + NADH + H+.
4778	succinyl-CoA hydrolase activity	F	Catalysis of the reaction: H(2)O + succinyl-CoA = CoA + H(+) + succinate.
4779	sulfate adenylyltransferase activity	F	Catalysis of the transfer of an adenylyl group from an adenosine nucleotide (ATP or ADP) to sulfate, forming adenylylsulfate.
4780	sulfate adenylyltransferase (ADP) activity	F	Catalysis of the reaction: ADP + H(+) + sulfate = 5'-adenylyl sulfate + phosphate.
4781	sulfate adenylyltransferase (ATP) activity	F	Catalysis of the reaction: ATP + sulfate = diphosphate + adenylylsulfate.
4782	sulfinoalanine decarboxylase activity	F	Catalysis of the reaction: 3-sulfino-L-alanine = hypotaurine + CO2.
4783	sulfite reductase (NADPH) activity	F	Catalysis of the reaction: hydrogen sulfide + 3 NADP+ + 3 H2O = sulfite + 3 NADPH + 3 H+.
4784	superoxide dismutase activity	F	Catalysis of the reaction: 2 superoxide + 2 H+ = O2 + hydrogen peroxide.
4787	thiamine-pyrophosphatase activity	F	Catalysis of the reaction: TDP + H2O = TMP + phosphate.
4788	thiamine diphosphokinase activity	F	Catalysis of the reaction: ATP + thiamine = AMP + thiamine diphosphate.
4789	thiamine-phosphate diphosphorylase activity	F	Catalysis of the reaction: 4-amino-2-methyl-5-diphosphomethylpyrimidine + 4-methyl-5-(2-phosphoethyl)-thiazole + H(+) = diphosphate + thiamine phosphate.
4790	thioether S-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine(1+) + dimethyl sulfide = S-adenosyl-L-homocysteine + trimethylsulfonium.
4791	thioredoxin-disulfide reductase activity	F	Catalysis of the reaction: NADP(+) + thioredoxin = H(+) + NADPH + thioredoxin disulfide.
4792	thiosulfate sulfurtransferase activity	F	Catalysis of the reaction: hydrogen cyanide + thiosulfate = H(+) + sulfite + thiocyanate.
4793	threonine aldolase activity	F	Catalysis of the reaction: L-threonine = glycine + acetaldehyde.
4794	L-threonine ammonia-lyase activity	F	Catalysis of the reaction: L-threonine = 2-oxobutanoate + NH3.
4795	threonine synthase activity	F	Catalysis of the reaction: O-phospho-L-homoserine + H2O = L-threonine + phosphate.
4796	thromboxane-A synthase activity	F	Catalysis of the reaction: prostaglandin H(2) = thromboxane A(2).
4797	thymidine kinase activity	F	Catalysis of the reaction: ATP + thymidine = ADP + thymidine 5'-phosphate.
4798	thymidylate kinase activity	F	Catalysis of the reaction: ATP + thymidine 5'-phosphate = ADP + thymidine 5'-diphosphate.
4799	thymidylate synthase activity	F	Catalysis of the reaction: 5,10-methylenetetrahydrofolate + dUMP = 7,8-dihydrofolate + thymidylate.
4800	thyroxine 5'-deiodinase activity	F	Catalysis of the reaction: 3,5,3'-L-triiodo-L-thyronine + iodide + acceptor + H+ = L-thyroxine + donor-H2.
4801	sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity	F	Catalysis of the reaction: sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate = D-erythrose 4-phosphate + D-fructose 6-phosphate.
4802	transketolase activity	F	Catalysis of the reversible transfer of a 2-carbon ketol group (CH2OH-CO-) from a ketose phosphate donor to an aldose phosphate acceptor.
4803	transposase activity	F	Catalysis of the transposition of transposable elements or transposons. Transposases are involved in recombination required for transposition and are site-specific for the transposon/transposable element.
4805	trehalose-phosphatase activity	F	Catalysis of the reaction: trehalose 6-phosphate + H2O = trehalose + phosphate.
4806	triglyceride lipase activity	F	Catalysis of the reaction: triacylglycerol + H2O = diacylglycerol + a carboxylate.
4807	triose-phosphate isomerase activity	F	Catalysis of the reaction: D-glyceraldehyde 3-phosphate = glycerone phosphate.
4808	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + tRNA containing 5-aminomethyl-2-thiouridine = S-adenosyl-L-homocysteine + tRNA containing 5-methylaminomethyl-2-thiouridylate.
4809	tRNA (guanine-N2-)-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + tRNA containing guanine = S-adenosyl-L-homocysteine + tRNA containing N2-methylguanine.
4810	tRNA adenylyltransferase activity	F	Catalysis of the reaction: ATP + tRNA(n) = diphosphate + tRNA(n+1).
4812	aminoacyl-tRNA ligase activity	F	Catalysis of the formation of aminoacyl-tRNA from ATP, amino acid, and tRNA with the release of diphosphate and AMP.
4813	alanine-tRNA ligase activity	F	Catalysis of the reaction: ATP + L-alanine + tRNA(Ala) = AMP + diphosphate + L-alanyl-tRNA(Ala).
4814	arginine-tRNA ligase activity	F	Catalysis of the reaction: ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).
4815	aspartate-tRNA ligase activity	F	Catalysis of the reaction: ATP + L-aspartate + tRNA(Asp) = AMP + diphosphate + L-aspartyl-tRNA(Asp).
4816	asparagine-tRNA ligase activity	F	Catalysis of the reaction: L-asparagine + ATP + tRNA(Asn) = AMP + Asn-tRNA(Asn) + diphosphate + 2 H(+).
4817	cysteine-tRNA ligase activity	F	Catalysis of the reaction: ATP + L-cysteine + tRNA(Cys) = AMP + diphosphate + L-cysteinyl-tRNA(Cys).
4818	glutamate-tRNA ligase activity	F	Catalysis of the reaction: ATP + L-glutamate + tRNA(Glu) = AMP + diphosphate + L-glutamyl-tRNA(Glu).
4819	glutamine-tRNA ligase activity	F	Catalysis of the reaction: ATP + L-glutamine + tRNA(Gln) = AMP + diphosphate + L-glutaminyl-tRNA(Gln).
4820	glycine-tRNA ligase activity	F	Catalysis of the reaction: ATP + glycine + tRNA(Gly) = AMP + diphosphate + glycyl-tRNA(Gly).
4821	histidine-tRNA ligase activity	F	Catalysis of the reaction: ATP + L-histidine + tRNA(His) = AMP + diphosphate + L-histidyl-tRNA(His).
4822	isoleucine-tRNA ligase activity	F	Catalysis of the reaction: L-isoleucine + ATP + tRNA(Ile) = L-isoleucyl-tRNA(Ile) + AMP + diphosphate + 2 H(+).
4823	leucine-tRNA ligase activity	F	Catalysis of the reaction: L-leucine + ATP + tRNA(Leu) = AMP + diphosphate + 2 H(+) + Leu-tRNA(Leu).
4824	lysine-tRNA ligase activity	F	Catalysis of the reaction: ATP + L-lysine + tRNA(Lys) = AMP + diphosphate + L-lysyl-tRNA(Lys).
4825	methionine-tRNA ligase activity	F	Catalysis of the reaction: ATP + L-methionine + tRNA(Met) = AMP + diphosphate + L-methionyl-tRNA(Met).
4826	phenylalanine-tRNA ligase activity	F	Catalysis of the reaction: ATP + L-phenylalanine + tRNA(Phe) = AMP + diphosphate + L-phenylalanyl-tRNA(Phe).
4827	proline-tRNA ligase activity	F	Catalysis of the reaction: ATP + L-proline + tRNA(Pro) = AMP + diphosphate + L-prolyl-tRNA(Pro).
4828	serine-tRNA ligase activity	F	Catalysis of the reaction: ATP + L-serine + tRNA(Ser) = AMP + diphosphate + L-seryl-tRNA(Ser).
4829	threonine-tRNA ligase activity	F	Catalysis of the reaction: ATP + L-threonine + tRNA(Thr) = AMP + diphosphate + L-threonyl-tRNA(Thr).
4830	tryptophan-tRNA ligase activity	F	Catalysis of the reaction: ATP + L-tryptophan + tRNA(Trp) = AMP + diphosphate + L-tryptophanyl-tRNA(Trp).
4831	tyrosine-tRNA ligase activity	F	Catalysis of the reaction: L-tyrosine + ATP + tRNA(Tyr) = L-tyrosyl-tRNA(Tyr) + AMP + diphosphate + 2 H(+).
4832	valine-tRNA ligase activity	F	Catalysis of the reaction: L-valine + ATP + tRNA(Val) = L-valyl-tRNA(Val) + AMP + diphosphate + 2 H(+).
4833	tryptophan 2,3-dioxygenase activity	F	Catalysis of the reaction: L-tryptophan + O2 = N-formyl-L-kynurenine.
4834	tryptophan synthase activity	F	Catalysis of the reaction: L-serine + (1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate = L-tryptophan + glyceraldehyde 3-phosphate + H2O.
4835	tubulin-tyrosine ligase activity	F	Catalysis of the reaction: ATP + detyrosinated alpha-tubulin + L-tyrosine = alpha-tubulin + ADP + phosphate.
4836	tyramine-beta hydroxylase activity	F	Catalysis of the hydroxylation of tyramine to form octopamine.
4837	tyrosine decarboxylase activity	F	Catalysis of the reaction: L-tyrosine = tyramine + CO2.
4838	L-tyrosine:2-oxoglutarate aminotransferase activity	F	Catalysis of the reaction: L-tyrosine + 2-oxoglutarate = 4-hydroxyphenylpyruvate + L-glutamate.
4839	ubiquitin activating enzyme activity	F	Catalysis of the reaction: E1 + ubiquitin + ATP--> E1-ubiquitin + AMP + PPi, where the E1-ubiquitin linkage is a thioester bond between the C-terminal glycine of Ub and a sulfhydryl side group of an E1 cysteine residue. This is the first step in a cascade of reactions in which ubiquitin is ultimately added to a protein substrate.
4842	ubiquitin-protein transferase activity	F	Catalysis of the transfer of ubiquitin from one protein to another via the reaction X-Ub + Y --> Y-Ub + X, where both X-Ub and Y-Ub are covalent linkages.
4843	thiol-dependent ubiquitin-specific protease activity	F	Catalysis of the thiol-dependent hydrolysis of a peptide bond formed by the C-terminal glycine of ubiquitin and another protein.
4844	uracil DNA N-glycosylase activity	F	Catalysis of the cleavage of the N-C1' glycosidic bond between the damaged DNA base and the deoxyribose sugar, releasing a free base and leaving an apyrimidinic (AP) site. Enzymes with this activity recognize and remove uracil bases in DNA that result from the deamination of cytosine or the misincorporation of dUTP opposite an adenine.
4845	uracil phosphoribosyltransferase activity	F	Catalysis of the reaction: diphosphate + UMP = 5-phospho-alpha-D-ribose 1-diphosphate + uracil.
4846	urate oxidase activity	F	Catalysis of the reaction: urate + O2 + H2O = 5-hydroxyisourate + hydrogen peroxide.
4847	urea carboxylase activity	F	Catalysis of the reaction: ATP + bicarbonate + urea = ADP + 2 H(+) + phosphate + urea-1-carboxylate.
4848	ureidoglycolate hydrolase activity	F	Catalysis of the reaction: (S)-ureidoglycolate + H(2)O + 2 H(+) = CO(2) + glyoxylate + 2 NH(4)(+).
4849	uridine kinase activity	F	Catalysis of the reaction: ATP + uridine = ADP + UMP.
4850	uridine phosphorylase activity	F	Catalysis of the reaction: uridine + phosphate = uracil + alpha-D-ribose 1-phosphate.
4851	uroporphyrin-III C-methyltransferase activity	F	Catalysis of the reaction: 2 S-adenosyl-L-methionine + uroporphyrin III = 2 S-adenosyl-L-homocysteine + precorrin-2.
4852	uroporphyrinogen-III synthase activity	F	Catalysis of the reaction: hydroxymethylbilane = H(2)O + uroporphyrinogen III.
4853	uroporphyrinogen decarboxylase activity	F	Catalysis of the reaction: uroporphyrinogen-III = coproporphyrinogen + 4 CO2.
4854	xanthine dehydrogenase activity	F	Catalysis of the reaction: xanthine + NAD+ + H2O = urate + NADH + H+.
4855	xanthine oxidase activity	F	Catalysis of the reaction: xanthine + H2O + O2 = urate + hydrogen peroxide.
4856	xylulokinase activity	F	Catalysis of the reaction: D-xylulose + ATP = D-xylulose 5-phosphate + ADP + 2 H(+).
4857	enzyme inhibitor activity	F	Binds to and stops, prevents or reduces the activity of an enzyme.
4858	dUTP pyrophosphatase inhibitor activity	F	Stops, prevents or reduces the activity of dUTP pyrophosphatase.
4859	phospholipase inhibitor activity	F	Stops, prevents or reduces the activity of a phospholipase, an enzyme that catalyzes of the hydrolysis of a phospholipid.
4860	protein kinase inhibitor activity	F	Stops, prevents or reduces the activity of a protein kinase, an enzyme which phosphorylates a protein.
4861	cyclin-dependent protein serine/threonine kinase inhibitor activity	F	Stops, prevents or reduces the activity of a cyclin-dependent protein serine/threonine kinase.
4862	cAMP-dependent protein kinase inhibitor activity	F	Stops, prevents or reduces the activity of a cAMP-dependent protein kinase.
4864	protein phosphatase inhibitor activity	F	Stops, prevents or reduces the activity of a protein phosphatase, an enzyme that hydrolyzes phosphate groups from phosphorylated proteins.
4865	protein serine/threonine phosphatase inhibitor activity	F	Stops, prevents or reduces the activity of a serine/threonine protein phosphatase, an enzyme that catalyzes the reaction: protein serine/threonine phosphate + H2O = protein serine/threonine + phosphate.
4866	endopeptidase inhibitor activity	F	Stops, prevents or reduces the activity of an endopeptidase, any enzyme that hydrolyzes nonterminal peptide bonds in polypeptides.
4867	serine-type endopeptidase inhibitor activity	F	Stops, prevents or reduces the activity of serine-type endopeptidases, enzymes that catalyze the hydrolysis of nonterminal peptide bonds in a polypeptide chain; a serine residue (and a histidine residue) are at the active center of the enzyme.
4869	cysteine-type endopeptidase inhibitor activity	F	Stops, prevents or reduces the activity of a cysteine-type endopeptidase, any enzyme that hydrolyzes peptide bonds in polypeptides by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile.
4871	signal transducer activity	F	Conveys a signal across a cell to trigger a change in cell function or state. A signal is a physical entity or change in state that is used to transfer information in order to trigger a response.
4872	receptor activity	F	Combining with an extracellular or intracellular messenger to initiate a change in cell activity.
4873	asialoglycoprotein receptor activity	F	Receiving an asialoglycoprotein, and delivering the asialoglycoprotein into the cell via endocytosis. An asialoglycoprotein is a plasma glycoproteins from which the terminal sialic acid residue on their complex carbohydrate groups has been removed. The asialoglycoprotein receptor recognizes the terminal galactose and N-acetylgalactosamine units of the asialoglycoprotein, the receptor-ligand complex is internalized and transported to a sorting organelle where disassociation occurs before the receptor is recycled to the cell membrane.
4874	aryl hydrocarbon receptor activity	F	Combining with an aryl hydrocarbon and transmitting the signal to initiate a change in cell activity. The aryl hydrocarbon receptor is a ligand-activated transcription factor which translocates to the nucleus to activate transcription upon ligand-binding.
4875	complement receptor activity	F	Combining with any component or product of the complement cascade and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
4876	complement component C3a receptor activity	F	Combining with the C3a product of the complement cascade and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
4877	complement component C3b receptor activity	F	Combining with the C3b product of the complement cascade and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
4878	complement component C5a receptor activity	F	Combining with the C5a product of the complement cascade and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
4879	RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding	F	Combining with a signal and transmitting the signal to the transcriptional machinery by interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription by RNA polymerase II.
4880	juvenile hormone receptor activity	F	Combining with juvenile hormone and transmitting the signal to the transcriptional machinery by interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription by RNA polymerase II.
4882	androgen receptor activity	F	Combining with an androgen and transmitting the signal to the transcriptional machinery by interacting selectively and non-covalently with an androgen response element in DNA in order to modulate transcription by RNA polymerase II.
4883	glucocorticoid receptor activity	F	Combining with a glucocorticoid and transmitting the signal within the cell trigger a change in cell activity or function.
4884	ecdysteroid hormone receptor activity	F	Combining with an ecdysteroid hormone and transmitting the signal to the transcriptional machinery by interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription by RNA polymerase II.
4886	9-cis retinoic acid receptor activity	F	Combining with 9-cis retinoic acid and transmitting the signal to the transcriptional machinery by interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription by RNA polymerase II.
4887	thyroid hormone receptor activity	F	Combining with thyroid hormone and transmitting the signal to the transcriptional machinery by interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription by RNA polymerase II.
4888	transmembrane signaling receptor activity	F	Combining with an extracellular or intracellular signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity or state as part of signal transduction.
4890	GABA-A receptor activity	F	Combining with the amino acid gamma-aminobutyric acid (GABA, 4-aminobutyrate) to initiate a change in cell activity. GABA-A receptors function as chloride channels.
4896	cytokine receptor activity	F	Combining with a cytokine and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
4897	ciliary neurotrophic factor receptor activity	F	Combining with ciliary neurotrophic factor (CNTF) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
4900	erythropoietin receptor activity	F	Combining with erythropoietin and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
4901	granulocyte macrophage colony-stimulating factor receptor activity	F	Combining with granulocyte macrophage colony-stimulating factor (GM-CSF) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
4902	granulocyte colony-stimulating factor receptor activity	F	Combining with granulocyte colony-stimulating factor (G-CSF) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
4903	growth hormone receptor activity	F	Combining with a growth hormone and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
4904	interferon receptor activity	F	Combining with an interferon and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
4905	type I interferon receptor activity	F	Combining with a type I interferon and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. Type I interferons include the interferon-alpha, beta, delta, epsilon, zeta, kappa, tau, and omega gene families.
4906	interferon-gamma receptor activity	F	Combining with interferon-gamma (a type II interferon) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
4908	interleukin-1 receptor activity	F	Combining with interleukin-1 to initiate a change in cell activity. Interleukin-1 is produced mainly by activated macrophages and is involved in the inflammatory response.
4909	interleukin-1, Type I, activating receptor activity	F	Combining with interleukin-1 to initiate a change in cell activity via signaling pathways and mediated by adaptor proteins.
4910	interleukin-1, Type II, blocking receptor activity	F	Combining with interleukin-1 to initiate a change in cell activity by inhibiting the activity of type I interleukin receptors.
4911	interleukin-2 receptor activity	F	Combining with interleukin-2 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
4912	interleukin-3 receptor activity	F	Combining with interleukin-3 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
4913	interleukin-4 receptor activity	F	Combining with interleukin-4 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
4914	interleukin-5 receptor activity	F	Combining with interleukin-5 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
4915	interleukin-6 receptor activity	F	Combining with interleukin-6 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
4917	interleukin-7 receptor activity	F	Combining with interleukin-7 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
4918	interleukin-8 receptor activity	F	Combining with interleukin-8 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
4919	interleukin-9 receptor activity	F	Combining with interleukin-9 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
4920	interleukin-10 receptor activity	F	Combining with interleukin-10 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
4921	interleukin-11 receptor activity	F	Combining with interleukin-11 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
4923	leukemia inhibitory factor receptor activity	F	Combining with leukemia inhibitory factor (LIF) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
4924	oncostatin-M receptor activity	F	Combining with oncostatin-M and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
4925	prolactin receptor activity	F	Combining with prolactin and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
4930	G-protein coupled receptor activity	F	Combining with an extracellular signal and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.
4931	extracellular ATP-gated cation channel activity	F	Enables the transmembrane transfer of a cation by a channel that opens when extracellular ATP has been bound by the channel complex or one of its constituent parts.
4932	mating-type factor pheromone receptor activity	F	Combining with a mating-type factor pheromone to initiate a change in cell activity.
4933	mating-type a-factor pheromone receptor activity	F	Combining with the mating-type a-factor pheromone to initiate a change in cell activity.
4934	mating-type alpha-factor pheromone receptor activity	F	Combining with the mating-type alpha-factor pheromone to initiate a change in cell activity.
4935	adrenergic receptor activity	F	Combining with epinephrine or norepinephrine and transmitting the signal across the membrane by activating the alpha-subunit of an associated heterotrimeric G-protein complex.
4936	alpha-adrenergic receptor activity	F	Combining with epinephrine or norepinephrine to initiate a change in cell activity via activation of a G protein, with pharmacological characteristics of alpha-adrenergic receptors.
4937	alpha1-adrenergic receptor activity	F	Combining with epinephrine or norepinephrine to initiate a change in cell activity via activation of a G protein, with pharmacological characteristics of alpha1-adrenergic receptors; the activity involves transmitting the signal to the Gq alpha subunit of a heterotrimeric G protein.
4938	alpha2-adrenergic receptor activity	F	Combining with epinephrine or norepinephrine to initiate a change in cell activity via activation of a G protein, with pharmacological characteristics of alpha2-adrenergic receptors; the activity involves transmitting the signal to the Gi alpha subunit of a heterotrimeric G protein.
4939	beta-adrenergic receptor activity	F	Combining with epinephrine or norepinephrine to initiate a change in cell activity via activation of a G protein, with pharmacological characteristics of beta-adrenergic receptors; the activity involves transmitting the signal to the Gs alpha subunit of a heterotrimeric G protein.
4940	beta1-adrenergic receptor activity	F	Combining with epinephrine or norepinephrine to initiate a change in cell activity via activation of a G protein, with pharmacological characteristics of beta1-adrenergic receptors.
4941	beta2-adrenergic receptor activity	F	Combining with epinephrine or norepinephrine to initiate a change in cell activity via activation of a G protein, with pharmacological characteristics of beta2-adrenergic receptors.
4945	angiotensin type II receptor activity	F	An angiotensin receptor activity that acts via Gi protein coupling and cGMP (NO) generation, and may also act via additional signaling mechanisms.
4946	bombesin receptor activity	F	Combining with bombesin to initiate a change in cell activity.
4947	bradykinin receptor activity	F	Combining with bradykinin to initiate a change in cell activity.
4948	calcitonin receptor activity	F	Combining with calcitonin and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.
4949	cannabinoid receptor activity	F	Combining with a cannabinoid to initiate a change in cell activity. Cannabinoids are a class of diverse chemical compounds that include the endocannabinoids and the phytocannabinoids.
4950	chemokine receptor activity	F	Combining with a chemokine, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. Chemokines are a family of small chemotactic cytokines; their name is derived from their ability to induce directed chemotaxis in nearby responsive cells. All chemokines possess a number of conserved cysteine residues involved in intramolecular disulfide bond formation. Some chemokines are considered pro-inflammatory and can be induced during an immune response to recruit cells of the immune system to a site of infection, while others are considered homeostatic and are involved in controlling the migration of cells during normal processes of tissue maintenance or development. Chemokines are found in all vertebrates, some viruses and some bacteria.
4951	cholecystokinin receptor activity	F	Combining with cholecystokinin and transmitting the signal across the membrane by activating an associated G-protein to initiate a change in cell activity. Cholecystokinin can act as a neuropeptide or as a gastrointestinal hormone.
4952	dopamine neurotransmitter receptor activity	F	Combining with the neurotransmitter dopamine to initiate a change in cell activity.
4953	icosanoid receptor activity	F	Combining with an icosanoid to initiate a change in cell activity.
4954	prostanoid receptor activity	F	Combining with a prostanoid, any compound based on or derived from the prostanoate structure, to initiate a change in cell activity.
4955	prostaglandin receptor activity	F	Combining with a prostaglandin (PG) to initiate a change in cell activity.
4956	prostaglandin D receptor activity	F	Combining with prostaglandin D (PGD(2)) to initiate a change in cell activity.
4957	prostaglandin E receptor activity	F	Combining with prostaglandin E (PGE(2)) to initiate a change in cell activity.
4958	prostaglandin F receptor activity	F	Combining with prostaglandin F (PGF (2-alpha)) to initiate a change in cell activity.
4960	thromboxane receptor activity	F	Combining with a thromboxane (TXA) to initiate a change in cell activity.
4961	thromboxane A2 receptor activity	F	Combining with thromboxane A2 (TXA(2)) and transmitting the signal across the membrane to activate an associated G-protein.
4962	endothelin receptor activity	F	Combining with endothelin and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.
4963	follicle-stimulating hormone receptor activity	F	Combining with follicle-stimulating hormone to initiate a change in cell activity.
4964	luteinizing hormone receptor activity	F	Combining with luteinizing hormone (also called lutropin) to initiate a change in cell activity.
4965	G-protein coupled GABA receptor activity	F	Combining with the amino acid gamma-aminobutyric acid (GABA, 4-aminobutyrate) and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.
4966	galanin receptor activity	F	Combining with galanin to initiate a change in cell activity.
4967	glucagon receptor activity	F	Combining with glucagon and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.
4968	gonadotropin-releasing hormone receptor activity	F	Combining with gonadotropin-releasing hormone to initiate a change in cell activity. Gonadotropin-releasing hormone (GnRH) is a peptide hormone responsible for the release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) from the anterior pituitary. GnRH is synthesized and released by the hypothalamus.
4969	histamine receptor activity	F	Combining with histamine to initiate a change in cell activity. Histamine is a physiologically active amine, found in plant and animal tissue and released from mast cells as part of an allergic reaction in humans.
4970	ionotropic glutamate receptor activity	F	Catalysis of the transmembrane transfer of an ion by a channel that opens when glutamate has been bound by the channel complex or one of its constituent parts.
4971	AMPA glutamate receptor activity	F	An ionotropic glutamate receptor activity that exhibits fast gating by glutamate and acts by opening a cation channel permeable to sodium, potassium, and, in the absence of a GluR2 subunit, calcium.
4972	NMDA glutamate receptor activity	F	An cation channel that opens in response to binding by extracellular glutmate, but only if glycine is also bound and the membrane is depolarized. Voltage gating is an indirect effects, due to ejection of bound magnesium from the pore at permissive voltages.
4974	leukotriene receptor activity	F	Combining with a leukotriene to initiate a change in cell activity. Leukotrienes are pharmacologically active substances with a set of three conjugated double bonds; some contain a peptide group based on cysteine.
4977	melanocortin receptor activity	F	Combining with melanocortin to initiate a change in cell activity.
4978	corticotropin receptor activity	F	Combining with corticotropin to initiate a change in cell activity.
4979	beta-endorphin receptor activity	F	Combining with beta-endorphin, and transmitting the signal across the membrane by activating an associated G-protein. Beta-endorphin is a peptide, 31 amino acids long, resulting from processing of the precursor proopiomelanocortin (POMC).
4980	melanocyte-stimulating hormone receptor activity	F	Combining with melanocyte-stimulating hormone to initiate a change in cell activity.
4982	N-formyl peptide receptor activity	F	Combining with an N-formyl peptide to initiate a change in cell activity.
4983	neuropeptide Y receptor activity	F	Combining with neuropeptide Y to initiate a change in cell activity.
4984	olfactory receptor activity	F	Combining with an odorant and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity in response to detection of smell.
4985	opioid receptor activity	F	Combining with an opioid (any narcotic derived from or resembling opium), and transmitting the signal across the membrane by activating an associated G-protein.
4989	octopamine receptor activity	F	Combining with the biogenic amine octopamine to initiate a change in cell activity. Octopamine is found in both vertebrates and invertebrates and can have properties both of a hormone and a neurotransmitter and acts as an adrenergic agonist.
4990	oxytocin receptor activity	F	Combining with oxytocin to initiate a change in cell activity.
4991	parathyroid hormone receptor activity	F	Combining with parathyroid hormone to initiate a change in cell activity.
4992	platelet activating factor receptor activity	F	Combining with platelet activating factor to initiate a change in cell activity.
4993	G-protein coupled serotonin receptor activity	F	Combining with the biogenic amine serotonin and transmitting the signal across the membrane by activating an associated G-protein. Serotonin (5-hydroxytryptamine) is a neurotransmitter and hormone found in vertebrates and invertebrates.
4994	somatostatin receptor activity	F	Combining with somatostatin to initiate a change in cell activity. Somatostatin is a peptide hormone that regulates the endocrine system by signaling via G-protein coupled somatostatin receptors. Somatostatin has two active forms produced by proteolytic cleavage: a 14 amino acid peptide (SST-14) and a 28 amino acid peptide (SST-28).
4995	tachykinin receptor activity	F	Combining with a tachykinin neuropeptide and transmitting the signal across the membrane by activating an associated G-protein.
4996	thyroid-stimulating hormone receptor activity	F	Combining with thyroid-stimulating hormone to initiate a change in cell activity.
4997	thyrotropin-releasing hormone receptor activity	F	Combining with thyrotropin-releasing hormone to initiate a change in cell activity.
4998	transferrin receptor activity	F	Combining selectively with transferrin, and delivering transferrin into the cell via endocytosis. Transferrin is a major iron carrier protein in vertebrates.
4999	vasoactive intestinal polypeptide receptor activity	F	Combining with vasoactive intestinal polypeptide to initiate a change in cell activity.
5000	vasopressin receptor activity	F	Combining with vasopressin to initiate a change in cell activity.
5001	transmembrane receptor protein tyrosine phosphatase activity	F	Combining with a signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: protein tyrosine phosphate + H2O = protein tyrosine + phosphate.
5003	ephrin receptor activity	F	Combining with an ephrin to initiate a change in cell activity.
5004	GPI-linked ephrin receptor activity	F	Combining with a GPI-anchored ephrin to initiate a change in cell activity.
5005	transmembrane-ephrin receptor activity	F	Combining with a transmembrane ephrin to initiate a change in cell activity.
5006	epidermal growth factor-activated receptor activity	F	Combining with an epidermal growth factor and transmitting the signal across the plasma membrane to initiate a change in cell activity.
5007	fibroblast growth factor-activated receptor activity	F	Combining with a fibroblast growth factor and transmitting the signal across the plasma membrane to initiate a change in cell activity.
5008	hepatocyte growth factor-activated receptor activity	F	Combining with hepatocyte growth factor and transmitting the signal across the plasma membrane to initiate a change in cell activity.
5009	insulin-activated receptor activity	F	Combining with insulin and transmitting the signal across the plasma membrane to initiate a change in cell activity.
5010	insulin-like growth factor-activated receptor activity	F	Combining with insulin-like growth factor and transmitting the signal across the plasma membrane to initiate a change in cell activity.
5011	macrophage colony-stimulating factor receptor activity	F	Combining with macrophage colony-stimulating factor (M-CSF) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: ATP + a protein-L-tyrosine = ADP + a protein-L-tyrosine phosphate.
5017	platelet-derived growth factor-activated receptor activity	F	Combining with platelet-derived growth factor and transmitting the signal across the plasma membrane to initiate a change in cell activity.
5018	platelet-derived growth factor alpha-receptor activity	F	Combining with platelet-derived growth factor isoform PDGF-AA, PDGF-BB or PDGF-AB to initiate a change in cell activity.
5019	platelet-derived growth factor beta-receptor activity	F	Combining with platelet-derived growth factor isoform PDGF-BB or PDGF-AB to initiate a change in cell activity.
5020	stem cell factor receptor activity	F	Combining with stem cell factor (SCF) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: ATP + a protein-L-tyrosine = ADP + a protein-L-tyrosine phosphate. Stem cell factor is a cytokine that stimulates mast cell growth and differentiation.
5021	vascular endothelial growth factor-activated receptor activity	F	Combining with a vascular endothelial growth factor (VEGF) and transmitting the signal across the plasma membrane to initiate a change in cell activity.
5024	transforming growth factor beta-activated receptor activity	F	Combining with a transforming growth factor beta (TGFbeta) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: ATP protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.
5025	transforming growth factor beta receptor activity, type I	F	Combining with a complex of transforming growth factor beta and a type II TGF-beta receptor to initiate a change in cell activity; upon binding, acts as a downstream transducer of TGF-beta signals.
5026	transforming growth factor beta receptor activity, type II	F	Combining with transforming growth factor beta to initiate a change in cell activity; upon ligand binding, binds to and catalyzes the phosphorylation of a type I TGF-beta receptor.
5030	neurotrophin receptor activity	F	Combining with a neurotrophin, any of a family of growth factors that prevent apoptosis in neurons and promote nerve growth, and transmitting the signal to initiate a change in cell activity.
5031	tumor necrosis factor-activated receptor activity	F	Combining with tumor necrosis factor, a proinflammatory cytokine produced by monocytes and macrophages, to initiate a change in cell function.
5034	osmosensor activity	F	Sensing extracellular osmolarity to initiate a change in cell activity, and spanning the membrane of the cell.
5035	death receptor activity	F	Combining with an extracellular messenger (called a death ligand), and transmitting the signal from one side of the plasma membrane to the other to initiate apoptotic or necrotic cell death.
5040	decoy death receptor activity	F	Combining with an extracellular messenger (death ligand) without transmission of the signal. Decoy death receptors compete with death receptors for ligand binding, and do not initiate apoptosis.
5041	low-density lipoprotein receptor activity	F	Combining with a low-density lipoprotein particle and delivering the low-density lipoprotein into the cell via endocytosis.
5042	netrin receptor activity	F	Combining with a netrin signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
5043	netrin receptor activity involved in chemorepulsion	F	Combining with a netrin signal and transmitting the signal from one side of the membrane to the other to contribute to the directed movement of a motile cell away from a higher concentration of netrin.
5044	scavenger receptor activity	F	Combining with any modified low-density lipoprotein (LDL) or other polyanionic ligand and delivering the ligand into the cell via endocytosis. Ligands include acetylated and oxidized LDL, Gram-positive and Gram-negative bacteria, apoptotic cells, beta-amyloid fibrils, and advanced glycation end products (AGEs).
5046	KDEL sequence binding	F	Interacting selectively and non-covalently with a KDEL sequence, the C terminus tetrapeptide sequence Lys-Asp-Glu-Leu found in proteins that are to be retained in the endoplasmic reticulum.
5047	signal recognition particle binding	F	Interacting selectively and non-covalently with the signal recognition particle.
5048	signal sequence binding	F	Interacting selectively and non-covalently with a signal sequence, a specific peptide sequence found on protein precursors or mature proteins that dictates where the mature protein is localized.
5049	nuclear export signal receptor activity	F	Combining with a nuclear export signal (NES) to mediate transport of the NES-containing protein through the nuclear pore to the cytoplasm.
5052	peroxisome matrix targeting signal-1 binding	F	Interacting selectively and non-covalently with a type 1 peroxisome targeting signal, a tripeptide with the consensus sequence (S/A/C)-(K/R/H)-L.
5053	peroxisome matrix targeting signal-2 binding	F	Interacting selectively and non-covalently with a type 2 peroxisome targeting signal, a nonapeptide with a broad consensus sequence of (R/K)-(L/V/I)-(XXXXX)-(H/Q)-(L/A/F).
5055	laminin receptor activity	F	Combining with a laminin, a glycoprotein that constitutes the majority of proteins in the basement membrane, to initiate a change in cell activity.
5056	tiggrin receptor activity	F	Combining with the extracellular matrix ligand tiggrin, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
5057	signal transducer activity, downstream of receptor	F	Conveys a signal from an upstream receptor or intracellular signal transducer, converting the signal into a form where it can ultimately trigger a change in the state or activity of a cell.
5068	transmembrane receptor protein tyrosine kinase adaptor activity	F	The binding activity of a molecule that brings together a transmembrane receptor protein tyrosine kinase and one or more other molecules, permitting them to function in a coordinated way.
5070	SH3/SH2 adaptor activity	F	Interacting selectively and non-covalently and simultaneously with one or more signal transduction molecules, usually acting as a scaffold to bring these molecules into close proximity either using their own SH2/SH3 domains (e.g. Grb2) or those of their target molecules (e.g. SAM68).
5072	transforming growth factor beta receptor, cytoplasmic mediator activity	F	Activity of any of the molecules that transmit the signal from a TGF-beta receptor through the cytoplasm to the nucleus.
5078	MAP-kinase scaffold activity	F	The binding activity of a molecule that functions as a physical support for the assembly of a multiprotein mitogen-activated protein kinase (MAPK) complex. Binds multiple kinases of the MAPKKK cascade, and also upstream signaling proteins, permitting those molecules to function in a coordinated way. Bringing together multiple enzymes and their substrates enables the signal to be transduced quickly and efficiently.
5080	protein kinase C binding	F	Interacting selectively and non-covalently with protein kinase C.
5085	guanyl-nucleotide exchange factor activity	F	Stimulates the exchange of guanyl nucleotides associated with a GTPase. Under normal cellular physiological conditions, the concentration of GTP is higher than that of GDP, favoring the replacement of GDP by GTP in association with the GTPase.
5086	ARF guanyl-nucleotide exchange factor activity	F	Stimulates the exchange of guanyl nucleotides associated with the GTPase ARF. Under normal cellular physiological conditions, the concentration of GTP is higher than that of GDP, favoring the replacement of GDP by GTP in association with the GTPase.
5087	Ran guanyl-nucleotide exchange factor activity	F	Stimulates the exchange of guanyl nucleotides associated with a GTPase of the Ran family. Under normal cellular physiological conditions, the concentration of GTP is higher than that of GDP, favoring the replacement of GDP by GTP in association with the GTPase.
5088	Ras guanyl-nucleotide exchange factor activity	F	Stimulates the exchange of guanyl nucleotides associated with a GTPase of the Ras superfamily. Under normal cellular physiological conditions, the concentration of GTP is higher than that of GDP, favoring the replacement of GDP by GTP in association with the GTPase.
5089	Rho guanyl-nucleotide exchange factor activity	F	Stimulates the exchange of guanyl nucleotides associated with a GTPase of the Rho family. Under normal cellular physiological conditions, the concentration of GTP is higher than that of GDP, favoring the replacement of GDP by GTP in association with the GTPase.
5090	Sar guanyl-nucleotide exchange factor activity	F	Stimulates the exchange of guanyl nucleotides associated with a GTPase of the Sar family. Under normal cellular physiological conditions, the concentration of GTP is higher than that of GDP, favoring the replacement of GDP by GTP in association with the GTPase.
5091	guanyl-nucleotide exchange factor adaptor activity	F	The binding activity of a molecule that brings together a guanyl-nucleotide exchange factor and one or more other proteins, permitting them to function in a coordinated way.
5092	GDP-dissociation inhibitor activity	F	Prevents the dissociation of GDP from a GTPase, thereby preventing GTP from binding.
5093	Rab GDP-dissociation inhibitor activity	F	Prevents the dissociation of GDP from the small GTPase Rab, thereby preventing GTP from binding.
5094	Rho GDP-dissociation inhibitor activity	F	Prevents the dissociation of GDP from the small GTPase Rho, thereby preventing GTP from binding.
5095	GTPase inhibitor activity	F	Stops, prevents or reduces the activity of any enzyme that catalyzes the hydrolysis of GTP to GDP and orthophosphate.
5096	GTPase activator activity	F	Binds to and increases the activity of a GTPase, an enzyme that catalyzes the hydrolysis of GTP.
5102	receptor binding	F	Interacting selectively and non-covalently with one or more specific sites on a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.
5104	fibroblast growth factor receptor binding	F	Interacting selectively and non-covalently with the fibroblast growth factor receptor (FGFR).
5105	type 1 fibroblast growth factor receptor binding	F	Interacting selectively and non-covalently with the type 1 fibroblast growth factor receptor (FGFR1).
5109	frizzled binding	F	Interacting selectively and non-covalently with the frizzled (fz) receptor.
5110	frizzled-2 binding	F	Interacting selectively and non-covalently with frizzled-2 (fz2).
5111	type 2 fibroblast growth factor receptor binding	F	Interacting selectively and non-covalently with the type 2 fibroblast growth factor receptor (FGFR2).
5112	Notch binding	F	Interacting selectively and non-covalently with the Notch (N) protein, a surface receptor.
5113	patched binding	F	Interacting selectively and non-covalently with the patched (ptc) protein, a receptor for hedgehog proteins.
5114	type II transforming growth factor beta receptor binding	F	Interacting selectively and non-covalently with a type II transforming growth factor beta receptor.
5115	receptor tyrosine kinase-like orphan receptor binding	F	Interacting selectively and non-covalently with the receptor tyrosine kinase-like orphan receptor (Ror).
5117	wishful thinking binding	F	Interacting selectively and non-covalently with wishful thinking (Wit), a type II bone morphogenic protein receptor.
5118	sevenless binding	F	Interacting selectively and non-covalently with the sevenless (sev) protein, a receptor tyrosine kinase.
5119	smoothened binding	F	Interacting selectively and non-covalently with the smoothened (smo) protein, which interacts with patched to transmit hedgehog signals.
5121	Toll binding	F	Interacting selectively and non-covalently with the Toll protein, a transmembrane receptor.
5122	torso binding	F	Interacting selectively and non-covalently with the torso (tor) protein, a receptor tyrosine kinase.
5123	death receptor binding	F	Interacting selectively and non-covalently with any member of the death receptor (DR) family. The DR family falls within the tumor necrosis factor receptor superfamily and is characterized by a cytoplasmic region of ~80 residues termed the death domain (DD).
5124	scavenger receptor binding	F	Interacting selectively and non-covalently with scavenger receptors, a family of proteins that are expressed on myeloid cells and are involved in the uptake of effete cellular components and foreign particles.
5125	cytokine activity	F	Functions to control the survival, growth, differentiation and effector function of tissues and cells.
5126	cytokine receptor binding	F	Interacting selectively and non-covalently with a cytokine receptor.
5127	ciliary neurotrophic factor receptor binding	F	Interacting selectively and non-covalently with the ciliary neurotrophic factor receptor.
5128	erythropoietin receptor binding	F	Interacting selectively and non-covalently with the erythropoietin receptor.
5129	granulocyte macrophage colony-stimulating factor receptor binding	F	Interacting selectively and non-covalently with the granulocyte macrophage colony-stimulating factor receptor.
5130	granulocyte colony-stimulating factor receptor binding	F	Interacting selectively and non-covalently with the granulocyte colony-stimulating factor receptor.
5131	growth hormone receptor binding	F	Interacting selectively and non-covalently with the growth hormone receptor.
5132	type I interferon receptor binding	F	Interacting selectively and non-covalently with an interferon-type I receptor, a heterodimeric complex composed of an alpha subunit (IFNAR1) and a beta subunit (IFNAR2).
5133	interferon-gamma receptor binding	F	Interacting selectively and non-covalently with the interferon-gamma receptor.
5134	interleukin-2 receptor binding	F	Interacting selectively and non-covalently with the interleukin-2 receptor.
5135	interleukin-3 receptor binding	F	Interacting selectively and non-covalently with the interleukin-3 receptor.
5136	interleukin-4 receptor binding	F	Interacting selectively and non-covalently with the interleukin-4 receptor.
5137	interleukin-5 receptor binding	F	Interacting selectively and non-covalently with the interleukin-5 receptor.
5138	interleukin-6 receptor binding	F	Interacting selectively and non-covalently with the interleukin-6 receptor.
5139	interleukin-7 receptor binding	F	Interacting selectively and non-covalently with the interleukin-7 receptor.
5140	interleukin-9 receptor binding	F	Interacting selectively and non-covalently with the interleukin-9 receptor.
5141	interleukin-10 receptor binding	F	Interacting selectively and non-covalently with the interleukin-10 receptor.
5142	interleukin-11 receptor binding	F	Interacting selectively and non-covalently with the interleukin-11 receptor.
5143	interleukin-12 receptor binding	F	Interacting selectively and non-covalently with the interleukin-12 receptor.
5144	interleukin-13 receptor binding	F	Interacting selectively and non-covalently with the interleukin-13 receptor.
5145	interleukin-14 receptor binding	F	Interacting selectively and non-covalently with the interleukin-14 receptor.
5146	leukemia inhibitory factor receptor binding	F	Interacting selectively and non-covalently with the leukemia inhibitory factor receptor.
5147	oncostatin-M receptor binding	F	Interacting selectively and non-covalently with the oncostatin-M receptor.
5148	prolactin receptor binding	F	Interacting selectively and non-covalently with the prolactin receptor.
5149	interleukin-1 receptor binding	F	Interacting selectively and non-covalently with the interleukin-1 receptor.
5150	interleukin-1, Type I receptor binding	F	Interacting selectively and non-covalently with a Type I interleukin-1 receptor.
5151	interleukin-1, Type II receptor binding	F	Interacting selectively and non-covalently with a Type II interleukin-1 receptor.
5152	interleukin-1 receptor antagonist activity	F	Blocks the binding of interleukin-1 to the interleukin-1 receptor complex.
5153	interleukin-8 receptor binding	F	Interacting selectively and non-covalently with the interleukin-8 receptor.
5154	epidermal growth factor receptor binding	F	Interacting selectively and non-covalently with the epidermal growth factor receptor.
5157	macrophage colony-stimulating factor receptor binding	F	Interacting selectively and non-covalently with the macrophage colony-stimulating factor receptor.
5158	insulin receptor binding	F	Interacting selectively and non-covalently with the insulin receptor.
5159	insulin-like growth factor receptor binding	F	Interacting selectively and non-covalently with the insulin-like growth factor receptor.
5160	transforming growth factor beta receptor binding	F	Interacting selectively and non-covalently with the transforming growth factor beta receptor.
5161	platelet-derived growth factor receptor binding	F	Interacting selectively and non-covalently with the platelet-derived growth factor receptor.
5163	nerve growth factor receptor binding	F	Interacting selectively and non-covalently with the nerve growth factor receptor.
5164	tumor necrosis factor receptor binding	F	Interacting selectively and non-covalently with the tumor necrosis factor receptor.
5165	neurotrophin receptor binding	F	Interacting selectively and non-covalently with a neurotrophin receptor.
5166	neurotrophin p75 receptor binding	F	Interacting selectively and non-covalently with the neurotrophin p75 receptor.
5167	neurotrophin TRK receptor binding	F	Interacting selectively and non-covalently with a neurotrophin TRK receptor.
5168	neurotrophin TRKA receptor binding	F	Interacting selectively and non-covalently with the neurotrophin TRKA receptor.
5169	neurotrophin TRKB receptor binding	F	Interacting selectively and non-covalently with the neurotrophin TRKB receptor.
5170	neurotrophin TRKC receptor binding	F	Interacting selectively and non-covalently with the neurotrophin TRKC receptor.
5171	hepatocyte growth factor receptor binding	F	Interacting selectively and non-covalently with the hepatocyte growth factor receptor.
5172	vascular endothelial growth factor receptor binding	F	Interacting selectively and non-covalently with any vascular endothelial growth factor receptor.
5173	stem cell factor receptor binding	F	Interacting selectively and non-covalently with the stem cell factor receptor (SCFR), a type III transmembrane kinase receptor.
5174	CD40 receptor binding	F	Interacting selectively and non-covalently with CD40, a receptor found on the surface of all B-lymphocytes.
5175	CD27 receptor binding	F	Interacting selectively and non-covalently with a CD27, a receptor found on the surface of T cells and some B cells and NK cells.
5176	ErbB-2 class receptor binding	F	Interacting selectively and non-covalently with the protein-tyrosine kinase receptor Neu/ErbB-2/HER2.
5178	integrin binding	F	Interacting selectively and non-covalently with an integrin.
5179	hormone activity	F	The action characteristic of a hormone, any substance formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells in the same organism, upon which it has a specific regulatory action. The term was originally applied to agents with a stimulatory physiological action in vertebrate animals (as opposed to a chalone, which has a depressant action). Usage is now extended to regulatory compounds in lower animals and plants, and to synthetic substances having comparable effects; all bind receptors and trigger some biological process.
5183	gonadotropin hormone-releasing hormone activity	F	The action characteristic of gonadotropin hormone-releasing hormone (GnRH), any of a family of decapeptide amide hormones that are released by the hypothalamus in response to neural and/or chemical stimuli. In at least mammals, upon receptor binding, GnRH causes the release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) by the anterior pituitary.
5184	neuropeptide hormone activity	F	The action characteristic of a neuropeptide hormone, any peptide hormone that acts in the central nervous system. A neuropeptide is any of several types of molecules found in brain tissue, composed of short chains of amino acids; they include endorphins, enkephalins, vasopressin, and others. They are often localized in axon terminals at synapses and are classified as putative neurotransmitters, although some are also hormones.
5185	neurohypophyseal hormone activity	F	The action characteristic of a neurohypophyseal hormone, any of a family of structurally and functionally related nonapeptides that are synthesized as part of a larger precursor molecule comprising a signal peptide, the nonapeptide hormone, and a neurophysin.
5186	pheromone activity	F	The activity of binding to and activating specific cell surface receptors, thereby inducing behavioral, developmental, or physiological response(s) from a responding organism or cell. The substance may be released or retained on the cell surface. Pheromones may serve as a specific attractant, social communicator, or sexual stimulant.
5198	structural molecule activity	F	The action of a molecule that contributes to the structural integrity of a complex or its assembly within or outside a cell.
5199	structural constituent of cell wall	F	The action of a molecule that contributes to the structural integrity of a cell wall.
5200	structural constituent of cytoskeleton	F	The action of a molecule that contributes to the structural integrity of a cytoskeletal structure.
5201	extracellular matrix structural constituent	F	The action of a molecule that contributes to the structural integrity of the extracellular matrix.
5212	structural constituent of eye lens	F	The action of a molecule that contributes to the structural integrity of the lens of an eye.
5213	structural constituent of chorion	F	The action of a molecule that contributes to the structural integrity of a chorion. An example of this is found in Drosophila melanogaster.
5214	structural constituent of chitin-based cuticle	F	The action of a molecule that contributes to the structural integrity of a chitin-based cuticle. An example of this is found in Drosophila melanogaster.
5215	transporter activity	F	Enables the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells.
5216	ion channel activity	F	Enables the facilitated diffusion of an ion (by an energy-independent process) by passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism. May be either selective (it enables passage of a specific ion only) or non-selective (it enables passage of two or more ions of same charge but different size).
5217	intracellular ligand-gated ion channel activity	F	Enables the transmembrane transfer of an ion by a channel that opens when a specific intracellular ligand has been bound by the channel complex or one of its constituent parts.
5219	ryanodine-sensitive calcium-release channel activity	F	Enables the transmembrane transfer of a calcium ion by a channel that opens when a ryanodine class ligand has been bound by the channel complex or one of its constituent parts.
5220	inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity	F	Enables the transmembrane transfer of a calcium ion by a channel that opens when inositol 1,4,5-trisphosphate (IP3) has been bound by the channel complex or one of its constituent parts.
5221	intracellular cyclic nucleotide activated cation channel activity	F	Enables the transmembrane transfer of a cation by a channel that opens when intracellular cyclic nucleotide has been bound by the channel complex or one of its constituent parts.
5222	intracellular cAMP activated cation channel activity	F	Enables the transmembrane transfer of a cation by a channel that opens when intracellular cAMP has been bound by the channel complex or one of its constituent parts.
5223	intracellular cGMP activated cation channel activity	F	Enables the transmembrane transfer of a cation by a channel that opens when intracellular cGMP has been bound by the channel complex or one of its constituent parts.
5225	volume-sensitive anion channel activity	F	Enables the transmembrane transfer of an anion by a volume-sensitive channel. An anion is a negatively charged ion. A volume-sensitive channel is a channel that responds to changes in the volume of a cell.
5227	calcium activated cation channel activity	F	Enables the calcium concentration-regulatable energy-independent passage of cations across a lipid bilayer down a concentration gradient.
5228	intracellular sodium activated potassium channel activity	F	Enables the transmembrane transfer of potassium by a channel that opens in response to stimulus by a sodium ion or ions. Transport by a channel involves facilitated diffusion of a solute (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel, without evidence for a carrier-mediated mechanism. Sodium activated potassium channels have distinctive properties, including a large single channel conductance, subconductance states, and a block of single channel currents at positive potentials, similar to inward rectification.
5229	intracellular calcium activated chloride channel activity	F	Enables the transmembrane transfer of chloride by a channel that opens in response to stimulus by a calcium ion or ions. Transport by a channel involves catalysis of facilitated diffusion of a solute (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel, without evidence for a carrier-mediated mechanism.
5230	extracellular ligand-gated ion channel activity	F	Enables the transmembrane transfer of an ion by a channel that opens when a specific extracellular ligand has been bound by the channel complex or one of its constituent parts.
5231	excitatory extracellular ligand-gated ion channel activity	F	Enables the transmembrane transfer of an ion by a channel that opens when a specific extracellular ligand has been bound by the channel complex or one of its constituent parts, where channel opening contributes to an increase in membrane potential.
5234	extracellular-glutamate-gated ion channel activity	F	Enables the transmembrane transfer of an ion by a channel that opens when extracellular glutamate has been bound by the channel complex or one of its constituent parts.
5237	inhibitory extracellular ligand-gated ion channel activity	F	Enables the transmembrane transfer of an ion by a channel that opens when a specific extracellular inhibitory ligand has been bound by the channel complex or one of its constituent parts. Inhibitory ligands, such as GABA or glycine, open chloride-selective channels.
5242	inward rectifier potassium channel activity	F	Enables the transmembrane transfer of a potassium ion by an inwardly-rectifying voltage-gated channel. An inwardly rectifying current-voltage relation is one where at any given driving force the inward flow of K+ ions exceeds the outward flow for the opposite driving force. The inward-rectification is due to a voltage-dependent block of the channel pore by a specific ligand or ligands, and as a result the macroscopic conductance depends on the difference between membrane voltage and the K+ equilibrium potential rather than on membrane voltage itself.
5243	gap junction channel activity	F	A wide pore channel activity that enables a direct cytoplasmic connection from one cell to an adjacent cell. The gap junction can pass large solutes as well as electrical signals between cells. Gap junctions consist of two gap junction hemi-channels, or connexons, one contributed by each membrane through which the gap junction passes.
5244	voltage-gated ion channel activity	F	Enables the transmembrane transfer of an ion by a voltage-gated channel. An ion is an atom or group of atoms carrying an electric charge by virtue of having gained or lost one or more electrons. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.
5245	voltage-gated calcium channel activity	F	Enables the transmembrane transfer of a calcium ion by a voltage-gated channel. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.
5246	calcium channel regulator activity	F	Modulates the activity of a calcium channel.
5247	voltage-gated chloride channel activity	F	Enables the transmembrane transfer of a chloride ion by a voltage-gated channel. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.
5248	voltage-gated sodium channel activity	F	Enables the transmembrane transfer of a sodium ion by a voltage-gated channel. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.
5249	voltage-gated potassium channel activity	F	Enables the transmembrane transfer of a potassium ion by a voltage-gated channel. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.
5250	A-type (transient outward) potassium channel activity	F	Enables the transmembrane transfer of a potassium ion by an outwardly-rectifying voltage-gated channel that produces a transient outward current upon a step change in membrane potential.
5251	delayed rectifier potassium channel activity	F	Enables the transmembrane transfer of a potassium ion by a delayed rectifying voltage-gated channel. A delayed rectifying current-voltage relation is one where channel activation kinetics are time-dependent, and inactivation is slow.
5252	open rectifier potassium channel activity	F	Enables the transmembrane transfer of a potassium ion by an open rectifier voltage-gated channel. An open rectifier current-voltage relationship is one in which the direction of rectification depends on the external potassium ion concentration.
5253	anion channel activity	F	Enables the energy-independent passage of anions across a lipid bilayer down a concentration gradient.
5254	chloride channel activity	F	Enables the facilitated diffusion of a chloride (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.
5260	intracellular ATPase-gated chloride channel activity	F	Enables passage of a chloride ion through a transmembrane channel that opens when intracellular ATP is bound and hydrolysed. Passage is via passive diffusion once the channel is open.
5261	cation channel activity	F	Enables the energy-independent passage of cations across a lipid bilayer down a concentration gradient.
5262	calcium channel activity	F	Enables the facilitated diffusion of a calcium ion (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.
5267	potassium channel activity	F	Enables the facilitated diffusion of a potassium ion (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.
5272	sodium channel activity	F	Enables the facilitated diffusion of a sodium ion (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.
5274	allantoin uptake transmembrane transporter activity	F	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: allantoin(out) + H+(out) = allantoin(in) + H+(in) by secondary active transport.
5275	amine transmembrane transporter activity	F	Enables the transfer of amines, including polyamines, from one side of the membrane to the other. Amines are organic compounds that are weakly basic in character and contain an amino (-NH2) or substituted amino group.
5276	vesicular hydrogen:amino acid antiporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a vesicle membrane to the other according to the reaction: H+(in) + amino acid(out) = H+(out) + amino acid(in).
5277	acetylcholine transmembrane transporter activity	F	Enables the transfer of acetylcholine from one side of the membrane to the other. Acetylcholine is an acetic acid ester of the organic base choline and functions as a neurotransmitter, released at the synapses of parasympathetic nerves and at neuromuscular junctions.
5278	acetylcholine:proton antiporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + acetylcholine(in) = H+(in) + acetylcholine(out).
5280	hydrogen:amino acid symporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: amino acid(out) + H+(out) = amino acid(in) + H+(in).
5283	sodium:amino acid symporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: amino acid(out) + Na+(out) = amino acid(in) + Na+(in).
5287	high-affinity basic amino acid transmembrane transporter activity	F	Catalysis of the transfer of basic amino acids from one side of a membrane to the other. Acidic amino acids have a pH above 7. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.
5289	high-affinity arginine transmembrane transporter activity	F	Catalysis of the transfer of arginine from one side of a membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.
5290	L-histidine transmembrane transporter activity	F	Enables the transfer of L-histidine from one side of a membrane to the other. L-histidine is 2-amino-3-(1H-imidazol-4-yl)propanoic acid.
5291	high-affinity L-histidine transmembrane transporter activity	F	Catalysis of the transfer of L-histidine from one side of a membrane to the other. L-histidine is 2-amino-3-(1H-imidazol-4-yl)propanoic acid. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.
5292	high-affinity lysine transmembrane transporter activity	F	Catalysis of the transfer of lysine from one side of a membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.
5294	neutral L-amino acid secondary active transmembrane transporter activity	F	Catalysis of the transfer of a neutral L-amino acid from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Chemiosmotic sources of energy include uniport, symport or antiport.
5295	neutral amino acid:sodium symporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: neutral amino acid(out) + Na+(out) = neutral amino acid(in) + Na+(in).
5297	hydrogen:proline symporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: proline(out) + H+(out) = proline(in) + H+(in).
5298	proline:sodium symporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: proline(out) + Na+(out) = proline(in) + Na+(in).
5300	high-affinity tryptophan transmembrane transporter activity	F	Catalysis of the high-affinity transfer of L-tryptophan from one side of a membrane to the other. Tryptophan is 2-amino-3-(1H-indol-3-yl)propanoic acid. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.
5302	L-tyrosine transmembrane transporter activity	F	Enables the transfer of L-tyrosine from one side of a membrane to the other. L-tyrosine is 2-amino-3-(4-hydroxyphenyl)propanoic acid.
5304	L-valine transmembrane transporter activity	F	Enables the transfer of L-valine from one side of a membrane to the other. L-valine is 2-amino-3-methylbutanoic acid.
5307	choline:sodium symporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: choline(out) + Na+(out) = choline(in) + Na+(in).
5308	creatine transmembrane transporter activity	F	Enables the directed movement of creatine across a membrane. Creatine is a compound synthesized from the amino acids arginine, glycine, and methionine that occurs in muscle.
5309	creatine:sodium symporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: creatine(out) + Na+(out) = creatine(in) + Na+(in).
5310	dicarboxylic acid transmembrane transporter activity	F	Enables the transfer of dicarboxylic acids from one side of the membrane to the other. A dicarboxylic acid is an organic acid with two COOH groups.
5313	L-glutamate transmembrane transporter activity	F	Enables the transfer of L-glutamate from one side of a membrane to the other. L-glutamate is the anion of 2-aminopentanedioic acid.
5314	high-affinity glutamate transmembrane transporter activity	F	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glutamate(out) + H+(out) = glutamate(in) + H+(in). In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.
5315	inorganic phosphate transmembrane transporter activity	F	Enables the transfer of a inorganic phosphate from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Chemiosmotic sources of energy include uniport, symport or antiport.
5316	high-affinity inorganic phosphate:sodium symporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: HPO42-(out) + Na+(out) = HPO42-(in) + Na+(in). In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.
5319	lipid transporter activity	F	Enables the directed movement of lipids into, out of or within a cell, or between cells.
5324	long-chain fatty acid transporter activity	F	Enables the directed movement of long-chain fatty acids into, out of or within a cell, or between cells. A long-chain fatty acid is a fatty acid with a chain length between C13 and C22.
5325	peroxisomal fatty-acyl-CoA transporter activity	F	Catalysis of the reaction: ATP + H2O + fatty acyl CoA(cis) = ADP + phosphate + fatty acyl CoA(trans). The transport of fatty acyl CoA into and out of peroxisomes.
5326	neurotransmitter transporter activity	F	Enables the directed movement of a neurotransmitter into, out of or within a cell, or between cells. Neurotransmitters are any chemical substance that is capable of transmitting (or inhibiting the transmission of) a nerve impulse from a neuron to another cell.
5328	neurotransmitter:sodium symporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: neurotransmitter(out) + Na+(out) = neurotransmitter(in) + Na+(in).
5329	dopamine transmembrane transporter activity	F	Enables the transfer of dopamine from one side of the membrane to the other. Dopamine is a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline.
5330	dopamine:sodium symporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: dopamine(out) + Na+(out) = dopamine(in) + Na+(in).
5332	gamma-aminobutyric acid:sodium symporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: gamma-aminobutyric acid(out) + Na+(out) = gamma-aminobutyric acid(in) + Na+(in).
5333	norepinephrine transmembrane transporter activity	F	Enables the transfer of norepinephrine from one side of the membrane to the other. Norepinephrine (3,4-dihydroxyphenyl-2-aminoethanol) is a hormone secreted by the adrenal medulla and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts of the CNS. It is also the biosynthetic precursor of epinephrine.
5334	norepinephrine:sodium symporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: norepinephrine(out) + Na+(out) = norepinephrine(in) + Na+(in).
5335	serotonin:sodium symporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: serotonin(out) + Na+(out) = serotonin(in) + Na+(in).
5337	nucleoside transmembrane transporter activity	F	Enables the transfer of a nucleoside, a nucleobase linked to either beta-D-ribofuranose (ribonucleoside) or 2-deoxy-beta-D-ribofuranose, (a deoxyribonucleotide) from one side of a membrane to the other.
5338	nucleotide-sugar transmembrane transporter activity	F	Enables the transfer of a nucleotide-sugar from one side of the membrane to the other. A nucleotide-sugar is any nucleotide in which the distal phosphoric residue of a nucleoside 5'-diphosphate is in glycosidic linkage with a monosaccharide or monosaccharide derivative.
5340	nucleotide-sulfate transmembrane transporter activity	F	Enables the transfer of nucleotide-sulfate from one side of a membrane to the other.
5342	organic acid transmembrane transporter activity	F	Enables the transfer of organic acids, any acidic compound containing carbon in covalent linkage, from one side of the membrane to the other.
5343	organic acid:sodium symporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: organic acid(out) + Na+(out) = organic acid(in) + Na+(in).
5344	oxygen transporter activity	F	Enables the directed movement of oxygen into, out of or within a cell, or between cells.
5345	purine nucleobase transmembrane transporter activity	F	Enables the transfer of purine nucleobases, one of the two classes of nitrogen-containing ring compounds found in DNA and RNA, from one side of a membrane to the other.
5346	purine ribonucleotide transmembrane transporter activity	F	Enables the transfer of a purine ribonucleotide, any compound consisting of a purine ribonucleoside (a purine organic base attached to a ribose sugar) esterified with (ortho)phosphate, from one side of a membrane to the other.
5347	ATP transmembrane transporter activity	F	Enables the transfer of ATP, adenosine triphosphate, from one side of a membrane to the other.
5350	pyrimidine nucleobase transmembrane transporter activity	F	Enables the transfer of pyrimidine nucleobases, one of the two classes of nitrogen-containing ring compounds found in DNA and RNA, from one side of a membrane to the other.
5351	sugar:proton symporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sugar(out) + H+(out) = sugar(in) + H+(in).
5352	alpha-glucoside:proton symporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: alpha-glucoside(out) + H+(out) = alpha-glucoside(in) + H+(in). Alpha-glucosides include trehalose, maltose, turanose, isomaltose, alpha-methylglucoside, maltotriose, palatinose, trehalose and melezitose.
5353	fructose transmembrane transporter activity	F	Enables the transfer of fructose from one side of the membrane to the other. Fructose exists in a open chain form or as a ring compound. D-fructose is the sweetest of the sugars and is found free in a large number of fruits and honey.
5354	galactose transmembrane transporter activity	F	Enables the transfer of galactose from one side of the membrane to the other. D-galactose is widely distributed in combined form in plants, animals and microorganisms as a constituent of oligo- and polysaccharides; it also occurs in galactolipids and as its glucoside in lactose and melibiose.
5355	glucose transmembrane transporter activity	F	Enables the transfer of the hexose monosaccharide glucose from one side of the membrane to the other.
5356	hydrogen:glucose symporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucose + H+ = glucose + H+. Symporter activity enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported together in the same direction in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy.
5357	constitutive hydrogen:glucose symporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucose + H+ = glucose + H+. This activity is constitutive and therefore always present, regardless of demand. Symporter activity enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported together in the same direction in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy.
5358	high-affinity hydrogen:glucose symporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucose + H+ = glucose + H+. This activity is constitutive and therefore always present, regardless of demand. Symporter activity enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported together in the same direction in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.
5359	low-affinity hydrogen:glucose symporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucose + H+ = glucose + H+. In low-affinity transport the transporter is able to bind the solute only if it is present at very high concentrations. Symporter activity enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported together in the same direction in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy.
5360	insulin-responsive hydrogen:glucose symporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucose + H+ = glucose + H+, in response to a stimulus by insulin. Symporter activity enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported together in the same direction in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy.
5362	low-affinity glucose:sodium symporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucose(out) + Na+(out) = glucose(in) + Na+(in). In low-affinity transport the transporter is able to bind the solute only if it is present at very high concentrations.
5363	maltose transmembrane transporter activity	F	Enables the transfer of maltose from one side of the membrane to the other. Maltose is the disaccharide 4-O-alpha-D-glucopyranosyl-D-glucopyranose, an intermediate in the enzymatic breakdown of glycogen and starch.
5364	maltose:proton symporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: maltose(out) + H+(out) = maltose(in) + H+(in).
5365	myo-inositol transmembrane transporter activity	F	Enables the transfer of myo-inositol from one side of the membrane to the other. Myo-inositol is 1,2,3,4,5/4,6-cyclohexanehexol, a growth factor for animals and microorganisms.
5366	myo-inositol:proton symporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: myo-inositol(out) + H+(out) = myo-inositol(in) + H+(in).
5367	myo-inositol:sodium symporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: myo-inositol(out) + Na+(out) = myo-inositol(in) + Na+(in).
5368	taurine transmembrane transporter activity	F	Enables the transfer of taurine from one side of the membrane to the other. Taurine (2-aminoethanesulfonic acid) is a sulphur-containing amino acid derivative which is important in the metabolism of fats.
5369	taurine:sodium symporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: taurine(out) + Na+(out) = taurine(in) + Na+(in).
5371	tricarboxylate secondary active transmembrane transporter activity	F	Catalysis of the transfer of tricarboxylate from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Chemiosmotic sources of energy include uniport, symport or antiport.
5372	water transmembrane transporter activity	F	Enables the directed movement of water (H2O) from one side of a membrane to the other.
5375	copper ion transmembrane transporter activity	F	Catalysis of the transfer of copper (Cu) ions from one side of a membrane to the other.
5381	iron ion transmembrane transporter activity	F	Catalysis of the transfer of iron (Fe) ions from one side of a membrane to the other.
5384	manganese ion transmembrane transporter activity	F	Catalysis of the transfer of manganese (Mn) ions from one side of a membrane to the other.
5385	zinc ion transmembrane transporter activity	F	Enables the transfer of zinc (Zn) ions from one side of a membrane to the other.
5388	calcium-transporting ATPase activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Ca2+(cis) = ADP + phosphate + Ca2+(trans).
5391	sodium:potassium-exchanging ATPase activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Na+(in) + K+(out) = ADP + phosphate + Na+(out) + K+(in).
5395	eye pigment precursor transporter activity	F	Catalysis of the reaction: ATP + H2O + eye pigment precursor(in) = ADP + phosphate + eye pigment precursor(out).
5402	cation:sugar symporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sugar(out) + cation(out) = sugar(in) + cation(in).
5412	glucose:sodium symporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucose(out) + Na+(out) = glucose(in) + Na+(in).
5415	nucleoside:sodium symporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: nucleoside(out) + Na+(out) = nucleoside(in) + Na+(in).
5416	cation:amino acid symporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: amino acid(out) + cation(out) = amino acid(in) + cation(in).
5427	proton-dependent oligopeptide secondary active transmembrane transporter activity	F	Catalysis of the transfer of a oligopeptide from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by proton movement.
5429	chromaffin granule amine transmembrane transporter activity	F	Enables the transfer of amines across chromaffin granule membranes.
5430	synaptic vesicle amine transmembrane transporter activity	F	Enables the transfer of amines across synaptic vesicle membranes.
5432	calcium:sodium antiporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Ca2+(in) + Na+(out) = Ca2+(out) + Na+(in).
5436	sodium:phosphate symporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Na+(out) + phosphate(out) = Na+(in) + phosphate(in).
5451	monovalent cation:proton antiporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: monovalent cation(out) + H+(in) = monovalent cation(in) + H+(out).
5452	inorganic anion exchanger activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: inorganic anion A(out) + inorganic anion B(in) = inorganic anion A(in) + inorganic anion B(out).
5456	CMP-N-acetylneuraminate transmembrane transporter activity	F	Enables the transfer of a CMP-N-acetylneuraminate from one side of the membrane to the other.
5457	GDP-fucose transmembrane transporter activity	F	Enables the transfer of a GDP-fucose from one side of the membrane to the other. GDP-fucose is a substance composed of fucose in glycosidic linkage with guanosine diphosphate.
5458	GDP-mannose transmembrane transporter activity	F	Enables the transfer of a GDP-mannose from one side of the membrane to the other. GDP-mannose is a substance composed of mannose in glycosidic linkage with guanosine diphosphate.
5459	UDP-galactose transmembrane transporter activity	F	Catalysis of the transfer of a UDP-galactose from one side of the membrane to the other. UDP-galactose is a substance composed of galactose in glycosidic linkage with uridine diphosphate.
5460	UDP-glucose transmembrane transporter activity	F	Enables the transfer of a UDP-glucose from one side of the membrane to the other. UDP-glucose is a substance composed of glucose in glycosidic linkage with uridine diphosphate.
5461	UDP-glucuronic acid transmembrane transporter activity	F	Catalysis of the transfer of a UDP-glucuronic acid from one side of the membrane to the other. UDP-glucuronic acid is a substance composed of glucuronic acid in glycosidic linkage with uridine diphosphate.
5462	UDP-N-acetylglucosamine transmembrane transporter activity	F	Enables the transfer of a UDP-N-acetylglucosamine from one side of the membrane to the other. N-acetylglucosamine is a substance composed of N-acetylglucosamine, a common structural unit of oligosaccharides, in glycosidic linkage with uridine diphosphate.
5463	UDP-N-acetylgalactosamine transmembrane transporter activity	F	Catalysis of the transfer of a N-acetylgalactosamine from one side of the membrane to the other. N-acetylgalactosamine is a substance composed of N-acetylgalactosamine, a common structural unit of oligosaccharides, in glycosidic linkage with uridine diphosphate.
5464	UDP-xylose transmembrane transporter activity	F	Enables the transfer of UDP-xylose from one side of the membrane to the other. UDP-xylose is a substance composed of xylose in glycosidic linkage with uridine diphosphate.
5469	succinate:fumarate antiporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: succinate(out) + fumarate(in) = succinate(in) + fumarate(out).
5471	ATP:ADP antiporter activity	F	Catalysis of the reaction: ATP(out) + ADP(in) = ATP(in) + ADP(out).
5472	FAD carrier activity	F	Catalysis of the transfer of flavin adenine dinucleotide from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Chemiosmotic sources of energy include uniport, symport or antiport.
5476	carnitine:acyl carnitine antiporter activity	F	Catalysis of the reaction: carnitine (mitochondrial) + acyl carnitine (cytoplasm) = carnitine (cytoplasm) + acyl carnitine (mitochondrial).
5477	pyruvate secondary active transmembrane transporter activity	F	Catalysis of the transfer of pyruvate from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Chemiosmotic sources of energy include uniport, symport or antiport.
5483	soluble NSF attachment protein activity	F	Interacting selectively and non-covalently with both N-ethylmaleimide-sensitive fusion protein (NSF) and a cis-SNARE complex (i.e. a SNARE complex in which all proteins are associated with the same membrane) and increasing the ATPase activity of NSF, thereby allowing ATP hydrolysis by NSF to disassemble the cis-SNARE complex.
5484	SNAP receptor activity	F	Acting as a marker to identify a membrane and interacting selectively with one or more SNAREs on another membrane to mediate membrane fusion.
5487	nucleocytoplasmic transporter activity	F	Enables the directed movement of substances between the nucleus and the cytoplasm of a cell.
5488	binding	F	The selective, non-covalent, often stoichiometric, interaction of a molecule with one or more specific sites on another molecule.
5496	steroid binding	F	Interacting selectively and non-covalently with a steroid, any of a large group of substances that have in common a ring system based on 1,2-cyclopentanoperhydrophenanthrene.
5497	androgen binding	F	Interacting selectively and non-covalently with any androgen, male sex hormones.
5499	vitamin D binding	F	Interacting selectively and non-covalently with vitamin D, any of a group of related, fat-soluble compounds that are derived from delta-5,7 steroids and play a central role in calcium metabolism. Specific forms of vitamin D include calciferol (ergocalciferol; vitamin D2) and cholecalciferol (calciol; vitamin D3).
5500	juvenile hormone binding	F	Interacting selectively and non-covalently with juvenile hormone, the three sesquiterpenoid derivatives that function to maintain the larval state of insects at molting and that may be required for other processes, e.g. oogenesis.
5501	retinoid binding	F	Interacting selectively and non-covalently with retinoids, any member of a class of isoprenoids that contain or are derived from four prenyl groups linked head-to-tail. Retinoids include retinol and retinal and structurally similar natural derivatives or synthetic compounds, but need not have vitamin A activity.
5502	11-cis retinal binding	F	Interacting selectively and non-covalently with 11-cis retinal, an isomer of retinal that plays an important role in the visual process in most vertebrates. 11-cis retinal combines with opsin in the rods (scotopsin) to form rhodopsin or visual purple. Retinal is one of the three compounds that makes up vitamin A.
5503	all-trans retinal binding	F	Interacting selectively and non-covalently with all-trans retinal, a compound that plays an important role in the visual process in most vertebrates. All-trans retinal (trans r., visual yellow) results from the bleaching of rhodopsin by light, in which the 11-cis form is converted to the all-trans form. Retinal is one of the forms of vitamin A.
5504	fatty acid binding	F	Interacting selectively and non-covalently with fatty acids, aliphatic monocarboxylic acids liberated from naturally occurring fats and oils by hydrolysis.
5506	iron ion binding	F	Interacting selectively and non-covalently with iron (Fe) ions.
5507	copper ion binding	F	Interacting selectively and non-covalently with copper (Cu) ions.
5509	calcium ion binding	F	Interacting selectively and non-covalently with calcium ions (Ca2+).
5513	detection of calcium ion	P	The series of events in which a calcium ion stimulus is received by a cell and converted into a molecular signal.
5515	protein binding	F	Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
5516	calmodulin binding	F	Interacting selectively and non-covalently with calmodulin, a calcium-binding protein with many roles, both in the calcium-bound and calcium-free states.
5518	collagen binding	F	Interacting selectively and non-covalently with collagen, a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. Collagen is highly enriched in glycine (some regions are 33% glycine) and proline, occurring predominantly as 3-hydroxyproline (about 20%).
5519	cytoskeletal regulatory protein binding	F	Interacting selectively and non-covalently with any protein involved in modulating the reorganization of the cytoskeleton.
5520	insulin-like growth factor binding	F	Interacting selectively and non-covalently with an insulin-like growth factor, any member of a group of polypeptides that are structurally homologous to insulin and share many of its biological activities, but are immunologically distinct from it.
5521	lamin binding	F	Interacting selectively and non-covalently with lamin; any of a group of intermediate-filament proteins that form the fibrous matrix on the inner surface of the nuclear envelope.
5522	profilin binding	F	Interacting selectively and non-covalently with profilin, an actin-binding protein that forms a complex with G-actin and prevents it from polymerizing to form F-actin.
5523	tropomyosin binding	F	Interacting selectively and non-covalently with tropomyosin, a protein associated with actin filaments both in cytoplasm and, in association with troponin, in the thin filament of striated muscle.
5524	ATP binding	F	Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
5525	GTP binding	F	Interacting selectively and non-covalently with GTP, guanosine triphosphate.
5527	macrolide binding	F	Interacting selectively and non-covalently with a macrolide, any of a large group of structurally related antibiotics produced by Streptomyces species.
5528	FK506 binding	F	Interacting selectively and non-covalently with the 23-membered macrolide lactone FK506.
5534	galactose binding	F	Interacting selectively and non-covalently with the aldohexose galactose (galacto-hexose), a common constituent of many oligo- and polysaccharides.
5536	glucose binding	F	Interacting selectively and non-covalently with the D- or L-enantiomer of glucose.
5537	mannose binding	F	Interacting selectively and non-covalently with mannose, a monosaccharide hexose, stereoisomeric with glucose, that occurs naturally only in polymerized forms called mannans.
5539	glycosaminoglycan binding	F	Interacting selectively and non-covalently with any glycan (polysaccharide) containing a substantial proportion of aminomonosaccharide residues.
5540	hyaluronic acid binding	F	Interacting selectively and non-covalently with hyaluronic acid, a polymer composed of repeating dimeric units of glucuronic acid and N-acetyl glucosamine.
5542	folic acid binding	F	Interacting selectively and non-covalently with folic acid, pteroylglutamic acid. Folic acid is widely distributed as a member of the vitamin B complex and is essential for the synthesis of purine and pyrimidines.
5543	phospholipid binding	F	Interacting selectively and non-covalently with phospholipids, a class of lipids containing phosphoric acid as a mono- or diester.
5544	calcium-dependent phospholipid binding	F	Interacting selectively and non-covalently with phospholipids, a class of lipids containing phosphoric acid as a mono- or diester, in the presence of calcium.
5545	1-phosphatidylinositol binding	F	Interacting selectively and non-covalently with phosphatidylinositol, any glycophospholipid with its sn-glycerol 3-phosphate residue is esterified to the 1-hydroxyl group of 1D-myo-inositol.
5546	phosphatidylinositol-4,5-bisphosphate binding	F	Interacting selectively and non-covalently with phosphatidylinositol-4,5-bisphosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 4' and 5' positions.
5547	phosphatidylinositol-3,4,5-trisphosphate binding	F	Interacting selectively and non-covalently with phosphatidylinositol-3,4,5-trisphosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 3', 4' and 5' positions.
5548	phospholipid transporter activity	F	Enables the directed movement of phospholipids into, out of or within a cell, or between cells. Phospholipids are a class of lipids containing phosphoric acid as a mono- or diester.
5549	odorant binding	F	Interacting selectively and non-covalently with an odorant, any substance capable of stimulating the sense of smell.
5550	pheromone binding	F	Interacting selectively and non-covalently with a pheromone, a substance, or characteristic mixture of substances, that is secreted and released by an organism and detected by a second organism of the same or a closely related species, in which it causes a specific reaction, such as a definite behavioral reaction or a developmental process.
5575	cellular_component	C	The part of a cell, extracellular environment or virus in which a gene product is located. A gene product may be located in one or more parts of a cell and its location may be as specific as a particular macromolecular complex, that is, a stable, persistent association of macromolecules that function together.
5576	extracellular region	C	The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
5577	fibrinogen complex	C	A highly soluble, elongated protein complex found in blood plasma and involved in clot formation. It is converted into fibrin monomer by the action of thrombin. In the mouse, fibrinogen is a hexamer, 46 nm long and 9 nm maximal diameter, containing two sets of nonidentical chains (alpha, beta, and gamma) linked together by disulfide bonds.
5578	proteinaceous extracellular matrix	C	A layer consisting mainly of proteins (especially collagen) and glycosaminoglycans (mostly as proteoglycans) that forms a sheet underlying or overlying cells such as endothelial and epithelial cells. The proteins are secreted by cells in the vicinity. An example of this component is found in Mus musculus.
5579	membrane attack complex	C	A protein complex produced by sequentially activated components of the complement cascade inserted into a target cell membrane and forming a pore leading to cell lysis via ion and water flow.
5581	collagen trimer	C	A protein complex consisting of three collagen chains assembled into a left-handed triple helix. These trimers typically assemble into higher order structures.
5582	collagen type XV trimer	C	A collagen homotrimer of alpha1(XV) chains; a chondroitin sulfate proteoglycan often found in specialized basement membranes where it bridges between fibrils.
5583	fibrillar collagen trimer	C	Any triple helical collagen trimer that forms fibrils.
5584	collagen type I trimer	C	A collagen trimer containing alpha(I) chains. The most common form of type I collagen is a heterotrimer containing two alpha1(I) chains and one alpha2(I) chain; homotrimers containing three alpha1(I) chains are also found. Type I collagen triple helices associate to form banded fibrils.
5585	collagen type II trimer	C	A collagen homotrimer of alpha1(II) chains; type II collagen triple helices associate to form fibrils.
5586	collagen type III trimer	C	A collagen homotrimer of alpha1(III) chains; type III collagen triple helices associate to form fibrils.
5587	collagen type IV trimer	C	A collagen heterotrimer containing type IV alpha chains; [alpha1(IV)]2alpha2(IV) trimers are commonly observed, although more type IV alpha chains exist and may be present in type IV trimers; type IV collagen triple helices associate to form 3 dimensional nets within basement membranes.
5588	collagen type V trimer	C	A collagen heterotrimer containing type V alpha chains; [alpha1(V)]2alpha2(V) and alpha1(V)alpha2(V)alpha3(V) trimers have been observed; type V collagen triple helices associate to form fibrils.
5589	collagen type VI trimer	C	A collagen heterotrimer containing type VI alpha chains in alpha1(VI)alpha2(VI)alpha3(VI) trimers; type VI collagen triple helices associate to form beaded fibrils.
5590	collagen type VII	C	A collagen homotrimer of alpha1(VII) chains; type VII collagen triple helices form antiparallel dimer, which in turn associate laterally to form anchoring fibrils that connect type IV collagen in the basal lamina to plaques in the underlying connective tissue.
5591	collagen type VIII trimer	C	A collagen heterotrimer containing type VIII alpha chains; [alpha1(VIII)2]alpha2(VIII) and alpha1(VIII)[alpha2(VIII)]2 trimers have been observed; type VIII collagen triple helices associate to form regular hexagonal nets.
5592	collagen type XI trimer	C	A collagen heterotrimer containing type XI alpha chains in alpha1(XI)alpha2(XI)alpha3(XI) trimers; type XI collagen triple helices associate to form fibrils.
5593	FACIT collagen trimer	C	A collagen trimer that associates with collagen fibrils and consists of collagen monomers that contain two or more relatively short triple-helical domains connected by non-triple-helical sequences.
5594	collagen type IX trimer	C	A collagen heterotrimer containing type IX alpha chains in alpha1(IX)alpha2(IX)alpha3(IX) trimers; type IX collagen triple helices associate to form a structure that links glycosaminoglycans to type II collagen fibrils.
5595	collagen type XII trimer	C	A collagen homotrimer of alpha1(XII) chains; type XII collagen triple helices may link sheet-forming or fibrillar collagens to other structures.
5596	collagen type XIV trimer	C	A collagen homotrimer of alpha1(XIV) chains; type XIV collagen triple helices may link sheet-forming or fibrillar collagens to other structures.
5597	collagen type XVI trimer	C	A collagen trimer containing alpha(XVI) chains; type XVI trimers can associate with microfibrils.
5598	short-chain collagen trimer	C	Any collagen trimer that does not form fibrils and that is relatively short compared to the collagen trimers that do form fibrils.
5599	collagen type X trimer	C	A collagen homotrimer of alpha1(X) chains; type X collagen triple helices form hexagonal networks (sheets).
5600	collagen type XIII trimer	C	A collagen homotrimer of alpha1(XIII) chains; type XIII collagen triple helices span the plasma membrane.
5601	classical-complement-pathway C3/C5 convertase complex	C	A heterodimeric protein complex that catalyzes the cleavage of complement components C3 and C5, and acts in the classical pathway of complement activation; consists of one monomer of C2a and one monomer of C4b; C2a is the catalytic subunit, but cannot catalyze cleavage alone.
5602	complement component C1 complex	C	A protein complex composed of six subunits of C1q, each formed of the three homologous polypeptide chains C1QA, C1QB, and C1QB, and tetramer of two C1QR and two C1QS polypeptide chains.
5604	basement membrane	C	A thin layer of dense material found in various animal tissues interposed between the cells and the adjacent connective tissue. It consists of the basal lamina plus an associated layer of reticulin fibers.
5605	basal lamina	C	A thin sheet of proteoglycans and glycoproteins, especially laminin, secreted by cells as an extracellular matrix.
5606	laminin-1 complex	C	A laminin complex composed of alpha1, beta1 and gamma1 polypeptide chains.
5607	laminin-2 complex	C	A laminin complex composed of alpha2, beta1 and gamma1 polypeptide chains.
5608	laminin-3 complex	C	A laminin complex composed of alpha1, beta2 and gamma1 polypeptide chains.
5609	laminin-4 complex	C	A laminin complex composed of alpha2, beta2 and gamma1 polypeptide chains.
5610	laminin-5 complex	C	A laminin complex composed of alpha3, beta3 and gamma2 polypeptide chains.
5611	laminin-6 complex	C	A laminin complex composed of alpha3, beta1 and gamma1 polypeptide chains.
5612	laminin-7 complex	C	A laminin complex composed of alpha3, beta2 and gamma1 polypeptide chains.
5614	interstitial matrix	C	A type of extracellular matrix found in interstitial connective tissue, characterized by the presence of fibronectins, proteoglycans, and types I, III, V, VI, VII and XII collagens.
5615	extracellular space	C	That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
5616	larval serum protein complex	C	A multisubunit protein complex which, in Drosophila, is a heterohexamer of three subunits, alpha, beta and gamma. The complex is thought to store amino acids for synthesis of adult proteins.
5618	cell wall	C	The rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal, most prokaryotic cells and some protozoan parasites, maintaining their shape and protecting them from osmotic lysis. In plants it is made of cellulose and, often, lignin; in fungi it is composed largely of polysaccharides; in bacteria it is composed of peptidoglycan; in protozoan parasites such as Giardia species, it's made of carbohydrates and proteins.
5619	ascospore wall	C	The specialized cell wall of the ascospore (spore), which is the product of meiotic division. Examples of this component are found in Fungi.
5621	cellular bud scar	C	Crater-like ring of chitinous scar tissue located on the surface of the mother cell. It is formed after the newly emerged daughter cell separates thereby marking the site of cytokinesis and septation. The number of bud scars that accumulate on the surface of a cell is a useful determinant of replicative age.
5622	intracellular	C	The living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.
5623	cell	C	The basic structural and functional unit of all organisms. Includes the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.
5628	prospore membrane	C	The prospore membrane is a double-membraned structure that extends from the cytoplasmic face of the spindle pole bodies to encompass the spindle pole bodies and the four nuclear lobes that are formed during meiosis. It helps isolate the meiotic nuclei from the cytoplasm during spore formation and serves as a foundation for the formation of the spore walls. An example of this component is found in Schizosaccharomyces pombe.
5630	dityrosine layer of spore wall	C	The outermost layer of the spore wall, as described in Saccharomyces.
5631	chitosan layer of spore wall	C	The second outermost layer of the spore wall, as described in Saccharomyces.
5632	inner layer of spore wall	C	Either of the two innermost layers of the spore wall, as described in Saccharomyces.
5633	ascus lipid particle	C	Any particle of coalesced lipids in an ascus or ascospore. May include associated proteins.
5634	nucleus	C	A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
5635	nuclear envelope	C	The double lipid bilayer enclosing the nucleus and separating its contents from the rest of the cytoplasm; includes the intermembrane space, a gap of width 20-40 nm (also called the perinuclear space).
5637	nuclear inner membrane	C	The inner, i.e. lumen-facing, lipid bilayer of the nuclear envelope.
5638	lamin filament	C	Any of a group of intermediate-filament proteins that form the fibrous matrix on the inner surface of the nuclear envelope. They are classified as lamins A, B and C.
5639	integral component of nuclear inner membrane	C	The component of the nuclear inner membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
5640	nuclear outer membrane	C	The outer, i.e. cytoplasm-facing, lipid bilayer of the nuclear envelope; continuous with the endoplasmic reticulum of the cell and sometimes studded with ribosomes.
5641	nuclear envelope lumen	C	The region between the two lipid bilayers of the nuclear envelope; 20-40 nm wide.
5642	annulate lamellae	C	Stacks of endoplasmic reticulum (ER) membranes containing a high density of nuclear pores, thought to form from excess nuclear membrane components, that have been described in a number of different cells. Annulate lamellar membranes are continuous with and embedded within the ER.
5643	nuclear pore	C	Any of the numerous similar discrete openings in the nuclear envelope of a eukaryotic cell, where the inner and outer nuclear membranes are joined.
5652	nuclear lamina	C	The fibrous, electron-dense layer lying on the nucleoplasmic side of the inner membrane of a cell nucleus, composed of lamin filaments. The polypeptides of the lamina are thought to be concerned in the dissolution of the nuclear envelope and its re-formation during mitosis. The lamina is composed of lamin A and lamin C filaments cross-linked into an orthogonal lattice, which is attached via lamin B to the inner nuclear membrane through interactions with a lamin B receptor, an IFAP, in the membrane.
5654	nucleoplasm	C	That part of the nuclear content other than the chromosomes or the nucleolus.
5655	nucleolar ribonuclease P complex	C	A ribonuclease P complex located in the nucleolus of a eukaryotic cell, where it catalyzes the 5' endonucleolytic cleavage of precursor tRNAs to yield mature tRNAs. Eukaryotic nucleolar ribonuclease P complexes generally contain a single RNA molecule that is necessary but not sufficient for catalysis, and several protein molecules.
5656	nuclear pre-replicative complex	C	A protein-DNA complex assembled at eukaryotic DNA replication origins during late mitosis and G1, allowing the origin to become competent, or 'licensed', for replication. The complex normally includes the origin recognition complex (ORC), Cdc6, Cdt1 and the MiniChromosome Maintenance (Mcm2-7) proteins.
5657	replication fork	C	The Y-shaped region of a replicating DNA molecule, resulting from the separation of the DNA strands and in which the synthesis of new strands takes place. Also includes associated protein complexes.
5658	alpha DNA polymerase:primase complex	C	A complex of four polypeptides, comprising large and small DNA polymerase alpha subunits and two primase subunits, which catalyzes the synthesis of an RNA primer on the lagging strand of replicating DNA; the smaller of the two primase subunits alone can catalyze oligoribonucleotide synthesis.
5662	DNA replication factor A complex	C	A conserved heterotrimeric complex that binds nonspecifically to single-stranded DNA and is required for multiple processes in eukaryotic DNA metabolism, including DNA replication, DNA repair, and recombination. In all eukaryotic organisms examined the complex is composed of subunits of approximately 70, 30, and 14 kDa.
5663	DNA replication factor C complex	C	A complex that loads the DNA polymerase processivity factor proliferating cell nuclear antigen (PCNA) onto DNA, thereby permitting processive DNA synthesis catalyzed by DNA polymerase. In eukaryotes the complex consists of five polypeptides.
5664	nuclear origin of replication recognition complex	C	A multisubunit complex that is located at the replication origins of a chromosome in the nucleus.
5665	DNA-directed RNA polymerase II, core complex	C	RNA polymerase II, one of three nuclear DNA-directed RNA polymerases found in all eukaryotes, is a multisubunit complex; typically it produces mRNAs, snoRNAs, and some of the snRNAs. Two large subunits comprise the most conserved portion including the catalytic site and share similarity with other eukaryotic and bacterial multisubunit RNA polymerases. The largest subunit of RNA polymerase II contains an essential carboxyl-terminal domain (CTD) composed of a variable number of heptapeptide repeats (YSPTSPS). The remainder of the complex is composed of smaller subunits (generally ten or more), some of which are also found in RNA polymerases I and III. Although the core is competent to mediate ribonucleic acid synthesis, it requires additional factors to select the appropriate template.
5666	DNA-directed RNA polymerase III complex	C	RNA polymerase III, one of three nuclear DNA-directed RNA polymerases found in all eukaryotes, is a multisubunit complex; typically it produces 5S rRNA, tRNAs and some of the small nuclear RNAs. Two large subunits comprise the most conserved portion including the catalytic site and share similarity with other eukaryotic and bacterial multisubunit RNA polymerases. The remainder of the complex is composed of smaller subunits (generally ten or more), some of which are also found in RNA polymerase I and others of which are also found in RNA polymerases I and II. Although the core is competent to mediate ribonucleic acid synthesis, it requires additional factors to select the appropriate template.
5667	transcription factor complex	C	A protein complex that is capable of associating with DNA by direct binding, or via other DNA-binding proteins or complexes, and regulating transcription.
5668	RNA polymerase transcription factor SL1 complex	C	A RNA polymerase I-specific transcription factor complex that contains the TATA-box-binding protein (TBP) and at least three TBP-associated factors including proteins known in mammals as TAFI110, TAFI63 and TAFI48.
5669	transcription factor TFIID complex	C	A complex composed of TATA binding protein (TBP) and TBP associated factors (TAFs); the total mass is typically about 800 kDa. Most of the TAFs are conserved across species. In TATA-containing promoters for RNA polymerase II (Pol II), TFIID is believed to recognize at least two distinct elements, the TATA element and a downstream promoter element. TFIID is also involved in recognition of TATA-less Pol II promoters. Binding of TFIID to DNA is necessary but not sufficient for transcription initiation from most RNA polymerase II promoters.
5671	Ada2/Gcn5/Ada3 transcription activator complex	C	A multiprotein complex that possesses histone acetyltransferase and is involved in regulation of transcription. Contains either GCN5 or PCAF in a mutually exclusive manner. The budding yeast complex includes Gcn5p, two proteins of the Ada family, and two TBP-associate proteins (TAFs); analogous complexes in other species have analogous compositions, and usually contain homologs of the yeast proteins. Both ATAC- or SAGA (see GO:0000124, SAGA complex) are involved in the acetylation of histone H3K9 and K14 residues.
5672	transcription factor TFIIA complex	C	A component of the transcription machinery of RNA Polymerase II. In humans, TFIIA is a heterotrimer composed of an alpha (P35), beta (P19) and gamma subunits (P12).
5673	transcription factor TFIIE complex	C	A transcription factor which in humans consists of a complex of two alpha and two beta chains. Recruits TFIIH to the initiation complex and helps activate both RNA polymerase II and TFIIH.
5674	transcription factor TFIIF complex	C	A general transcription initiation factor which in humans consists of a heterodimer of an alpha and a beta subunit. Helps recruit RNA polymerase II to the initiation complex and promotes translation elongation.
5675	holo TFIIH complex	C	A complex that is capable of kinase activity directed towards the C-terminal Domain (CTD) of the largest subunit of RNA polymerase II and is essential for initiation at RNA polymerase II promoters in vitro. It is composed of the core TFIIH complex and the TFIIK complex.
5677	chromatin silencing complex	C	Any protein complex that mediates changes in chromatin structure that result in transcriptional silencing.
5680	anaphase-promoting complex	C	A ubiquitin ligase complex that degrades mitotic cyclins and anaphase inhibitory protein, thereby triggering sister chromatid separation and exit from mitosis. Substrate recognition by APC occurs through degradation signals, the most common of which is termed the Dbox degradation motif, originally discovered in cyclin B.
5681	spliceosomal complex	C	Any of a series of ribonucleoprotein complexes that contain snRNA(s) and small nuclear ribonucleoproteins (snRNPs), and are formed sequentially during the spliceosomal splicing of one or more substrate RNAs, and which also contain the RNA substrate(s) from the initial target RNAs of splicing, the splicing intermediate RNA(s), to the final RNA products. During cis-splicing, the initial target RNA is a single, contiguous RNA transcript, whether mRNA, snoRNA, etc., and the released products are a spliced RNA and an excised intron, generally as a lariat structure. During trans-splicing, there are two initial substrate RNAs, the spliced leader RNA and a pre-mRNA.
5682	U5 snRNP	C	A ribonucleoprotein complex that contains small nuclear RNA U5.
5683	U7 snRNP	C	A ribonucleoprotein complex that contains the U7 snRNA and is required for the 3'-end processing of replication-dependent histone pre-mRNAs.
5684	U2-type spliceosomal complex	C	Any spliceosomal complex that forms during the splicing of a messenger RNA primary transcript to excise an intron that has canonical consensus sequences near the 5' and 3' ends.
5685	U1 snRNP	C	A ribonucleoprotein complex that contains small nuclear RNA U1.
5686	U2 snRNP	C	A ribonucleoprotein complex that contains small nuclear RNA U2.
5687	U4 snRNP	C	A ribonucleoprotein complex that contains small nuclear RNA U4.
5688	U6 snRNP	C	A ribonucleoprotein complex that contains small nuclear RNA U6.
5689	U12-type spliceosomal complex	C	Any spliceosomal complex that forms during the splicing of a messenger RNA primary transcript to excise an intron; the series of U12-type spliceosomal complexes is involved in the splicing of the majority of introns that contain atypical AT-AC terminal dinucleotides, as well as other non-canonical introns. The entire splice site signal, not just the terminal dinucleotides, is involved in determining which spliceosome utilizes the site.
5690	U4atac snRNP	C	A ribonucleoprotein complex that contains small nuclear RNA U4atac.
5691	U6atac snRNP	C	A ribonucleoprotein complex that contains small nuclear RNA U6atac.
5692	U11 snRNP	C	A ribonucleoprotein complex that contains small nuclear RNA U11.
5693	U12 snRNP	C	A ribonucleoprotein complex that contains small nuclear RNA U12.
5694	chromosome	C	A structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information.
5697	telomerase holoenzyme complex	C	Telomerase is a ribonucleoprotein enzyme complex, with a minimal catalytic core composed of a catalytic reverse transcriptase subunit and an RNA subunit that provides the template for telomeric DNA addition. In vivo, the holoenzyme complex often contains additional subunits.
5700	polytene chromosome	C	A type of chromosome in a polyploid cell, formed when multiple copies of homologous chromosomes are aligned side by side to give a giant chromosome in which distinct chromosome bands are readily visible.
5701	polytene chromosome chromocenter	C	A region at which the centric regions of polytene chromosomes are joined together.
5702	polytene chromosome weak point	C	A region of the polytene chromosome where the diameter is considerably decreased, probably resulting from local differences in chromosome organization.
5703	polytene chromosome puff	C	A swelling at a site along the length of a polytene chromosome, thought to be the site of active transcription.
5704	polytene chromosome band	C	A stretch of densely packed chromatin along the polytene chromosome, visible as a morphologically distinct band.
5705	polytene chromosome interband	C	A stretch of less tightly packed chromatin along the polytene chromosome, found between bands.
5706	polytene chromosome ectopic fiber	C	A thread-like connection joining two regions of ectopically paired polytene chromosomes.
5712	chiasma	C	A connection formed between chromatids, visible during meiosis, thought to be the point of the interchange involved in crossing-over.
5713	recombination nodule	C	An electron dense structure that is associated with meiotic chromosomes.
5714	early recombination nodule	C	An electron dense structure that is associated with meiotic chromosomes in leptotene or zygotene during meiosis I.
5715	late recombination nodule	C	An electron dense structure that is associated with meiotic chromosomes in pachytene during meiosis I.
5719	nuclear euchromatin	C	The dispersed less dense form of chromatin in the interphase nucleus. It exists in at least two forms, a some being in the form of transcriptionally active chromatin which is the least condensed, while the rest is inactive euchromatin which is more condensed than active chromatin but less condensed than heterochromatin.
5720	nuclear heterochromatin	C	A condensed form of chromatin, occurring in the nucleus during interphase, that stains strongly with basophilic dyes. The DNA of heterochromatin is typically replicated at a later stage in the cell-division cycle than euchromatin.
5721	pericentric heterochromatin	C	Heterochromatin that is located adjacent to the CENP-A rich centromere 'central core' and characterized by the modified histone H3K9me3.
5722	beta-heterochromatin	C	A diffusely banded region of heterochromatin located between euchromatin and alpha-heterochromatin in the polytene chromosome chromocenter; normally replicated during polytenization.
5723	alpha-heterochromatin	C	A small, compact region of heterochromatin located in the middle of the polytene chromosome chromocenter, which undergoes little or no replication during polytenization.
5724	nuclear telomeric heterochromatin	C	Heterochromatic regions of the chromosome found at the telomeres of a chromosome in the nucleus.
5725	intercalary heterochromatin	C	Any of the regions of heterochromatin that form a reproducible set of dense bands scattered along the euchromatic arms in polytene chromosomes.
5726	perichromatin fibrils	C	Structures of variable diameter visible in the nucleoplasm by electron microscopy, mainly observed near the border of condensed chromatin. The fibrils are enriched in RNA, and are believed to be sites of pre-mRNA splicing and polyadenylylation representing the in situ form of nascent transcripts.
5727	extrachromosomal circular DNA	C	Circular DNA structures that are not part of a chromosome.
5728	extrachromosomal rDNA circle	C	Circular DNA molecules encoding ribosomal RNA that are replicated independently of chromosomal replication. These molecules originate in the chromosome but are excised and circularized, often by intramolecular homologous recombination between direct tandem repeats.
5729	2-micrometer circle DNA	C	A plasmid commonly found in Saccharomyces, inherited in a non-Mendelian manner and often present in 100-400 copies.
5730	nucleolus	C	A small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis. Its prime function is the transcription of the nucleolar DNA into 45S ribosomal-precursor RNA, the processing of this RNA into 5.8S, 18S, and 28S components of ribosomal RNA, and the association of these components with 5S RNA and proteins synthesized outside the nucleolus. This association results in the formation of ribonucleoprotein precursors; these pass into the cytoplasm and mature into the 40S and 60S subunits of the ribosome.
5731	nucleolus organizer region	C	A region of a chromosome where nucleoli form during interphase, and where genes encoding the largest rRNA precursor transcript are tandemly arrayed.
5732	small nucleolar ribonucleoprotein complex	C	A ribonucleoprotein complex that contains an RNA molecule of the small nucleolar RNA (snoRNA) family and associated proteins. Most are involved in a step of processing of rRNA: cleavage, 2'-O-methylation, or pseudouridylation. The majority, though not all, fall into one of two classes, box C/D type or box H/ACA type.
5736	DNA-directed RNA polymerase I complex	C	RNA polymerase I, one of three nuclear DNA-directed RNA polymerases found in all eukaryotes, is a multisubunit complex; typically it produces rRNAs. Two large subunits comprise the most conserved portion including the catalytic site and share similarity with other eukaryotic and bacterial multisubunit RNA polymerases. The remainder of the complex is composed of smaller subunits (generally ten or more), some of which are also found in RNA polymerase III and others of which are also found in RNA polymerases II and III. Although the core is competent to mediate ribonucleic acid synthesis, it requires additional factors to select the appropriate template.
5737	cytoplasm	C	All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
5739	mitochondrion	C	A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
5740	mitochondrial envelope	C	The double lipid bilayer enclosing the mitochondrion and separating its contents from the cell cytoplasm; includes the intermembrane space.
5741	mitochondrial outer membrane	C	The outer, i.e. cytoplasm-facing, lipid bilayer of the mitochondrial envelope.
5742	mitochondrial outer membrane translocase complex	C	A large complex of the mitochondrial outer membrane that mediates transport of proteins into all mitochondrial compartments.
5743	mitochondrial inner membrane	C	The inner, i.e. lumen-facing, lipid bilayer of the mitochondrial envelope. It is highly folded to form cristae.
5744	mitochondrial inner membrane presequence translocase complex	C	The protein transport machinery of the mitochondrial inner membrane that contains three essential Tim proteins: Tim17 and Tim23 are thought to build a preprotein translocation channel while Tim44 interacts transiently with the matrix heat-shock protein Hsp70 to form an ATP-driven import motor.
5745	m-AAA complex	C	Protease complex of the mitochondrial inner membrane that is involved in mitochondrial protein turnover and in processing of proteins imported into mitochondria.
5746	mitochondrial respiratory chain	C	The protein complexes that form the mitochondrial electron transport system (the respiratory chain), associated with the inner mitochondrial membrane. The respiratory chain complexes transfer electrons from an electron donor to an electron acceptor and are associated with a proton pump to create a transmembrane electrochemical gradient.
5747	mitochondrial respiratory chain complex I	C	A protein complex located in the mitochondrial inner membrane that forms part of the mitochondrial respiratory chain. It contains about 25 different polypeptide subunits, including NADH dehydrogenase (ubiquinone), flavin mononucleotide and several different iron-sulfur clusters containing non-heme iron. The iron undergoes oxidation-reduction between Fe(II) and Fe(III), and catalyzes proton translocation linked to the oxidation of NADH by ubiquinone.
5749	mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)	C	A protein complex located in the mitochondrial inner membrane that forms part of the mitochondrial respiratory chain. Contains the four polypeptide subunits of succinate dehydrogenase, flavin-adenine dinucleotide and iron-sulfur. Catalyzes the oxidation of succinate by ubiquinone. Connects the TCA cycle with the respiratory chain.
5750	mitochondrial respiratory chain complex III	C	A protein complex located in the mitochondrial inner membrane that forms part of the mitochondrial respiratory chain. Contains about 10 polypeptide subunits including four redox centers: cytochrome b/b6, cytochrome c1 and an 2Fe-2S cluster. Catalyzes the oxidation of ubiquinol by oxidized cytochrome c1.
5751	mitochondrial respiratory chain complex IV	C	A protein complex located in the mitochondrial inner membrane that forms part of the mitochondrial respiratory chain. Contains the 13 polypeptide subunits of cytochrome c oxidase, including cytochrome a and cytochrome a3. Catalyzes the oxidation of reduced cytochrome c by dioxygen (O2).
5753	mitochondrial proton-transporting ATP synthase complex	C	A proton-transporting ATP synthase complex found in the mitochondrial membrane.
5754	mitochondrial proton-transporting ATP synthase, catalytic core	C	The hexamer, comprising three alpha and three beta subunits, that possesses the catalytic activity of the mitochondrial hydrogen-transporting ATP synthase.
5756	mitochondrial proton-transporting ATP synthase, central stalk	C	One of two stalks that connect the catalytic core of the hydrogen-transporting ATP synthase to the mitochondrial membrane-associated F0 proteins; rotates within the catalytic core during catalysis.
5757	mitochondrial permeability transition pore complex	C	A protein complex that connects the inner and outer membranes of animal mitochondria and acts as a pore that can open transiently to allow free diffusion of solutes between the mitochondrial matrix and the cytosol. The pore complex is formed of the voltage-dependent anion channel (VDAC), the adenine nucleotide translocase (ANT) and cyclophilin-D (CyP-D).
5758	mitochondrial intermembrane space	C	The region between the inner and outer lipid bilayers of the mitochondrial envelope.
5759	mitochondrial matrix	C	The gel-like material, with considerable fine structure, that lies in the matrix space, or lumen, of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and, in some organisms, the enzymes concerned with fatty acid oxidation.
5760	gamma DNA polymerase complex	C	A DNA polymerase complex consisting of a large subunit, responsible for the catalytic activities, and a small accessory subunit. Functions in the replication and repair of mitochondrial DNA.
5761	mitochondrial ribosome	C	A ribosome found in the mitochondrion of a eukaryotic cell; contains a characteristic set of proteins distinct from those of cytosolic ribosomes.
5762	mitochondrial large ribosomal subunit	C	The larger of the two subunits of a mitochondrial ribosome. Two sites on the ribosomal large subunit are involved in translation: the aminoacyl site (A site) and peptidyl site (P site).
5763	mitochondrial small ribosomal subunit	C	The smaller of the two subunits of a mitochondrial ribosome.
5764	lysosome	C	A small lytic vacuole that has cell cycle-independent morphology and is found in most animal cells and that contains a variety of hydrolases, most of which have their maximal activities in the pH range 5-6. The contained enzymes display latency if properly isolated. About 40 different lysosomal hydrolases are known and lysosomes have a great variety of morphologies and functions.
5765	lysosomal membrane	C	The lipid bilayer surrounding the lysosome and separating its contents from the cell cytoplasm.
5766	primary lysosome	C	A lysosome before it has fused with a vesicle or vacuole.
5767	secondary lysosome	C	Vacuole formed by the fusion of a lysosome with an organelle (autosome) or with a primary phagosome.
5768	endosome	C	A vacuole to which materials ingested by endocytosis are delivered.
5769	early endosome	C	A membrane-bounded organelle that receives incoming material from primary endocytic vesicles that have been generated by clathrin-dependent and clathrin-independent endocytosis; vesicles fuse with the early endosome to deliver cargo for sorting into recycling or degradation pathways.
5770	late endosome	C	A prelysosomal endocytic organelle differentiated from early endosomes by lower lumenal pH and different protein composition. Late endosomes are more spherical than early endosomes and are mostly juxtanuclear, being concentrated near the microtubule organizing center.
5771	multivesicular body	C	A type of endosome in which regions of the limiting endosomal membrane invaginate to form internal vesicles; membrane proteins that enter the internal vesicles are sequestered from the cytoplasm.
5773	vacuole	C	A closed structure, found only in eukaryotic cells, that is completely surrounded by unit membrane and contains liquid material. Cells contain one or several vacuoles, that may have different functions from each other. Vacuoles have a diverse array of functions. They can act as a storage organelle for nutrients or waste products, as a degradative compartment, as a cost-effective way of increasing cell size, and as a homeostatic regulator controlling both turgor pressure and pH of the cytosol.
5774	vacuolar membrane	C	The lipid bilayer surrounding the vacuole and separating its contents from the cytoplasm of the cell.
5775	vacuolar lumen	C	The volume enclosed within the vacuolar membrane.
5776	autophagosome	C	A double-membrane-bounded compartment that engulfs endogenous cellular material as well as invading microorganisms to target them to the vacuole/lysosome for degradation as part of macroautophagy.
5777	peroxisome	C	A small organelle enclosed by a single membrane, and found in most eukaryotic cells. Contains peroxidases and other enzymes involved in a variety of metabolic processes including free radical detoxification, lipid catabolism and biosynthesis, and hydrogen peroxide metabolism.
5778	peroxisomal membrane	C	The lipid bilayer surrounding a peroxisome.
5779	integral component of peroxisomal membrane	C	The component of the peroxisomal membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
5780	extrinsic component of intraperoxisomal membrane	C	The component of the intraperoxisomal membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
5782	peroxisomal matrix	C	The volume contained within the membranes of a peroxisome; in many cells the matrix contains a crystalloid core largely composed of urate oxidase.
5783	endoplasmic reticulum	C	The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
5784	Sec61 translocon complex	C	A translocon complex that contains a core heterotrimer of conserved alpha, beta and gamma subunits, and may contain additional proteins (translocon-associated proteins or TRAPs); in budding yeast the core proteins are Sec61p, Sbh1p, and Sss1p. The Sec61 translocon complex functions in cotranslational and posttranslational translocation events.
5785	signal recognition particle receptor complex	C	A transmembrane heterodimeric protein located in the membrane of the rough endoplasmic reticulum. Both subunits contain GTPase domains with which signal recognition particle interacts. In the presence of GTP and SRP receptor, SRP is released from the ribosome-nascent chain complex.
5786	signal recognition particle, endoplasmic reticulum targeting	C	A ribonucleoprotein particle of 325 kDa composed of a 7S (300 nucleotide) RNA molecule and a complex of six different polypeptides. This binds both to the N-terminal signal peptide for proteins destined for the endoplasmic reticulum as they emerge from the large ribosomal subunit and also to the ribosome. This binding arrests further translation thereby preventing the proteins from being released into the cytosol. The SRP-ribosome complex then diffuses to the endoplasmic reticulum where it is bound to the signal recognition particle receptor, which allows resumption of protein synthesis and facilitates the passage of the growing polypeptide chain through the translocon. Through a process involving GTP hydrolysis, the SRP-SRP receptor complex dissociates and SRP returns to the cytosol. Of the six polypeptides of SRP the 54 kDa subunit (SRP54) is the central player. It contains an N-terminal GTPase domain and a C-terminal domain that binds directly to the signal peptide and the SRP RNA. Examples of this component are found in Mus musculus, Saccharomyces cerevisiae and Arabidopsis thaliana.
5787	signal peptidase complex	C	A protein complex that is located in the endoplasmic reticulum membrane and cleaves the signal sequence from precursor proteins following their transport out of the cytoplasmic space.
5788	endoplasmic reticulum lumen	C	The volume enclosed by the membranes of the endoplasmic reticulum.
5789	endoplasmic reticulum membrane	C	The lipid bilayer surrounding the endoplasmic reticulum.
5790	smooth endoplasmic reticulum	C	The smooth endoplasmic reticulum (smooth ER or SER) has no ribosomes attached to it. The smooth ER is the recipient of the proteins synthesized in the rough ER. Those proteins to be exported are passed to the Golgi complex, the resident proteins are returned to the rough ER and the lysosomal proteins after phosphorylation of their mannose residues are passed to the lysosomes. Glycosylation of the glycoproteins also continues. The smooth ER is the site of synthesis of lipids, including the phospholipids. The membranes of the smooth ER also contain enzymes that catalyze a series of reactions to detoxify both lipid-soluble drugs and harmful products of metabolism. Large quantities of certain compounds such as phenobarbital cause an increase in the amount of the smooth ER.
5791	rough endoplasmic reticulum	C	The rough (or granular) endoplasmic reticulum (ER) has ribosomes adhering to the outer surface; the ribosomes are the site of translation of the mRNA for those proteins which are either to be retained within the cisternae (ER-resident proteins), the proteins of the lysosomes, or the proteins destined for export from the cell. Glycoproteins undergo their initial glycosylation within the cisternae.
5793	endoplasmic reticulum-Golgi intermediate compartment	C	A complex system of membrane-bounded compartments located between endoplasmic reticulum (ER) and the Golgi complex, with a distinctive membrane protein composition; involved in ER-to-Golgi and Golgi-to-ER transport.
5794	Golgi apparatus	C	A compound membranous cytoplasmic organelle of eukaryotic cells, consisting of flattened, ribosome-free vesicles arranged in a more or less regular stack. The Golgi apparatus differs from the endoplasmic reticulum in often having slightly thicker membranes, appearing in sections as a characteristic shallow semicircle so that the convex side (cis or entry face) abuts the endoplasmic reticulum, secretory vesicles emerging from the concave side (trans or exit face). In vertebrate cells there is usually one such organelle, while in invertebrates and plants, where they are known usually as dictyosomes, there may be several scattered in the cytoplasm. The Golgi apparatus processes proteins produced on the ribosomes of the rough endoplasmic reticulum; such processing includes modification of the core oligosaccharides of glycoproteins, and the sorting and packaging of proteins for transport to a variety of cellular locations. Three different regions of the Golgi are now recognized both in terms of structure and function: cis, in the vicinity of the cis face, trans, in the vicinity of the trans face, and medial, lying between the cis and trans regions.
5795	Golgi stack	C	The set of thin, flattened membrane-bounded compartments, called cisternae, that form the central portion of the Golgi complex. The stack usually comprises cis, medial, and trans cisternae; the cis- and trans-Golgi networks are not considered part of the stack.
5796	Golgi lumen	C	The volume enclosed by the membranes of any cisterna or subcompartment of the Golgi apparatus, including the cis- and trans-Golgi networks.
5797	Golgi medial cisterna	C	The middle Golgi cisterna (or cisternae).
5798	Golgi-associated vesicle	C	Any vesicle associated with the Golgi complex and involved in mediating transport within the Golgi or between the Golgi and other parts of the cell.
5801	cis-Golgi network	C	The network of interconnected tubular and cisternal structures located at the convex side of the Golgi apparatus, which abuts the endoplasmic reticulum.
5802	trans-Golgi network	C	The network of interconnected tubular and cisternal structures located within the Golgi apparatus on the side distal to the endoplasmic reticulum, from which secretory vesicles emerge. The trans-Golgi network is important in the later stages of protein secretion where it is thought to play a key role in the sorting and targeting of secreted proteins to the correct destination.
5811	lipid particle	C	An intracellular non-membrane-bounded organelle comprising a matrix of coalesced lipids surrounded by a phospholipid monolayer. May include associated proteins.
5813	centrosome	C	A structure comprised of a core structure (in most organisms, a pair of centrioles) and peripheral material from which a microtubule-based structure, such as a spindle apparatus, is organized. Centrosomes occur close to the nucleus during interphase in many eukaryotic cells, though in animal cells it changes continually during the cell-division cycle.
5814	centriole	C	A cellular organelle, found close to the nucleus in many eukaryotic cells, consisting of a small cylinder with microtubular walls, 300-500 nm long and 150-250 nm in diameter. It contains nine short, parallel, peripheral microtubular fibrils, each fibril consisting of one complete microtubule fused to two incomplete microtubules. Cells usually have two centrioles, lying at right angles to each other. At division, each pair of centrioles generates another pair and the twin pairs form the pole of the mitotic spindle.
5815	microtubule organizing center	C	An intracellular structure that can catalyze gamma-tubulin-dependent microtubule nucleation and that can anchor microtubules by interacting with their minus ends, plus ends or sides.
5816	spindle pole body	C	The microtubule organizing center in fungi; functionally homologous to the animal cell centrosome.
5818	aster	C	An array of microtubules emanating from a spindle pole MTOC that do not connect to kinetochores.
5819	spindle	C	The array of microtubules and associated molecules that forms between opposite poles of a eukaryotic cell during mitosis or meiosis and serves to move the duplicated chromosomes apart.
5821	intermediate layer of spindle pole body	C	Structure between the central and outer plaques of the spindle pole body.
5822	inner plaque of spindle pole body	C	One of three laminate structures that form the spindle pole body; the inner plaque is in the nucleus.
5823	central plaque of spindle pole body	C	One of three laminate structures that form the spindle pole body; the central plaque is embedded in the nuclear envelope.
5824	outer plaque of spindle pole body	C	One of three laminate structures that form the spindle pole body; the outer plaque is in the cytoplasm.
5825	half bridge of spindle pole body	C	Structure adjacent to the plaques of the spindle pole body.
5826	actomyosin contractile ring	C	A cytoskeletal structure composed of actin filaments and myosin that forms beneath the plasma membrane of many cells, including animal cells and yeast cells, in a plane perpendicular to the axis of the spindle, i.e. the cell division plane. Ring contraction is associated with centripetal growth of the membrane that divides the cytoplasm of the two daughter cells. In animal cells, the contractile ring is located inside the plasma membrane at the location of the cleavage furrow. In budding fungal cells, e.g. mitotic S. cerevisiae cells, the contractile ring forms beneath the plasma membrane at the mother-bud neck before mitosis.
5827	polar microtubule	C	Any of the spindle microtubules that come from each pole and overlap at the spindle midzone. This interdigitating structure consisting of antiparallel microtubules is responsible for pushing the poles of the spindle apart.
5828	kinetochore microtubule	C	Any of the spindle microtubules that attach to the kinetochores of chromosomes by their plus ends, and maneuver the chromosomes during mitotic or meiotic chromosome segregation.
5829	cytosol	C	The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
5831	steroid hormone aporeceptor complex	C	A protein complex consisting of a steroid receptor associated with nonreceptor proteins, minimally a dimer of Hsp90 and a monomer of hsp56/FKBP59; forms in the absence of bound ligand.
5832	chaperonin-containing T-complex	C	A multisubunit ring-shaped complex that mediates protein folding in the cytosol without a cofactor.
5833	hemoglobin complex	C	An iron-containing, oxygen carrying complex. In vertebrates it is made up of two pairs of associated globin polypeptide chains, each chain carrying a noncovalently bound heme prosthetic group.
5834	heterotrimeric G-protein complex	C	Any of a family of heterotrimeric GTP-binding and hydrolyzing proteins; they belong to a superfamily of GTPases that includes monomeric proteins such as EF-Tu and RAS. Heterotrimeric G-proteins consist of three subunits; the alpha subunit contains the guanine nucleotide binding site and possesses GTPase activity; the beta and gamma subunits are tightly associated and function as a beta-gamma heterodimer; extrinsic plasma membrane proteins (cytoplasmic face) that function as a complex to transduce signals from G-protein coupled receptors to an effector protein.
5835	fatty acid synthase complex	C	A multienzyme complex that catalyses the synthesis of fatty acids from acetyl CoA.
5836	fatty-acyl-CoA synthase complex	C	A protein complex that possesses fatty-acyl-CoA synthase activity.
5838	proteasome regulatory particle	C	A multisubunit complex, which caps one or both ends of the proteasome core complex. This complex recognizes and unfolds ubiquitinated proteins, and translocates them to the proteasome core complex.
5839	proteasome core complex	C	A multisubunit barrel shaped endoprotease complex, which is the core of the proteasome complex.
5840	ribosome	C	An intracellular organelle, about 200 A in diameter, consisting of RNA and protein. It is the site of protein biosynthesis resulting from translation of messenger RNA (mRNA). It consists of two subunits, one large and one small, each containing only protein and RNA. Both the ribosome and its subunits are characterized by their sedimentation coefficients, expressed in Svedberg units (symbol: S). Hence, the prokaryotic ribosome (70S) comprises a large (50S) subunit and a small (30S) subunit, while the eukaryotic ribosome (80S) comprises a large (60S) subunit and a small (40S) subunit. Two sites on the ribosomal large subunit are involved in translation, namely the aminoacyl site (A site) and peptidyl site (P site). Ribosomes from prokaryotes, eukaryotes, mitochondria, and chloroplasts have characteristically distinct ribosomal proteins.
5844	polysome	C	A multiribosomal structure representing a linear array of ribosomes held together by messenger RNA. They represent the active complexes in cellular protein synthesis and are able to incorporate amino acids into polypeptides both in vivo and in vitro.
5845	mRNA cap binding complex	C	Any protein complex that binds to an mRNA cap at any time in the lifetime of the mRNA.
5846	nuclear cap binding complex	C	A conserved heterodimeric protein complex that binds to the 5' terminal cap structure m7G(5')ppp(5')N of nascent eukaryotic RNA polymerase II transcripts such as pre-mRNA and U snRNA. The consists of proteins known as CBP20 and CBP80, binds to cap structures in the nucleus, and is involved in pre-mRNA splicing, 3'-end formation, and RNA nuclear export.
5847	mRNA cleavage and polyadenylation specificity factor complex	C	A multisubunit complex that binds to the canonical AAUAAA hexamer and to U-rich upstream sequence elements on the pre-mRNA, thereby stimulating the otherwise weakly active and nonspecific polymerase to elongate efficiently RNAs containing a poly(A) signal.
5848	mRNA cleavage stimulating factor complex	C	A protein complex required for mRNA cleavage but not for poly(A) addition.
5849	mRNA cleavage factor complex	C	Any macromolecular complex involved in cleavage or polyadenylation of mRNA molecules.
5850	eukaryotic translation initiation factor 2 complex	C	Complex of three heterogeneous polypeptide chains, that form a ternary complex with initiator methionyl-tRNA and GTP. This ternary complex binds to free 40S subunit, which subsequently binds the 5' end of mRNA.
5851	eukaryotic translation initiation factor 2B complex	C	A multisubunit guanine nucleotide exchange factor which catalyzes the exchange of GDP bound to initiation factor eIF2 for GTP, generating active eIF2-GTP. In humans, it is composed of five subunits, alpha, beta, delta, gamma and epsilon.
5852	eukaryotic translation initiation factor 3 complex	C	A complex of several polypeptides that plays at least two important roles in protein synthesis: First, eIF3 binds to the 40S ribosome and facilitates loading of the Met-tRNA/eIF2.GTP ternary complex to form the 43S preinitiation complex. Subsequently, eIF3 apparently assists eIF4 in recruiting mRNAs to the 43S complex. The eIF3 complex contains five conserved core subunits, and may contain several additional proteins; the non-core subunits are thought to mediate association of the complex with specific sets of mRNAs.
5853	eukaryotic translation elongation factor 1 complex	C	A multisubunit nucleotide exchange complex that binds GTP and aminoacyl-tRNAs, and catalyzes their codon-dependent placement at the A-site of the ribosome. In humans, the complex is composed of four subunits, alpha, beta, delta and gamma.
5854	nascent polypeptide-associated complex	C	A heterodimeric protein complex that can reversibly bind to ribosomes, and is located in direct proximity to newly synthesized polypeptide chains as they emerge from the ribosome.
5856	cytoskeleton	C	Any of the various filamentous elements that form the internal framework of cells, and typically remain after treatment of the cells with mild detergent to remove membrane constituents and soluble components of the cytoplasm. The term embraces intermediate filaments, microfilaments, microtubules, the microtrabecular lattice, and other structures characterized by a polymeric filamentous nature and long-range order within the cell. The various elements of the cytoskeleton not only serve in the maintenance of cellular shape but also have roles in other cellular functions, including cellular movement, cell division, endocytosis, and movement of organelles.
5858	axonemal dynein complex	C	A dynein complex found in eukaryotic cilia and flagella; the motor domain heads interact with adjacent microtubules to generate a sliding force which is converted to a bending motion.
5859	muscle myosin complex	C	A filament of myosin found in a muscle cell of any type.
5861	troponin complex	C	A complex of accessory proteins (typically troponin T, troponin I and troponin C) found associated with actin in muscle thin filaments; involved in calcium regulation of muscle contraction.
5862	muscle thin filament tropomyosin	C	A form of the tropomyosin dimer found associated with actin and the troponin complex in muscle thin filaments.
5863	striated muscle myosin thick filament	C	Bipolar filaments formed of polymers of a muscle-specific myosin II isoform, found in the middle of sarcomeres in myofibrils.
5865	striated muscle thin filament	C	Filaments formed of actin and associated proteins; attached to Z discs at either end of sarcomeres in myofibrils.
5868	cytoplasmic dynein complex	C	Any dynein complex with a homodimeric dynein heavy chain core that catalyzes movement along a microtubule. Cytoplasmic dynein complexes participate in many cytoplasmic transport activities in eukaryotes, such as mRNA localization, intermediate filament transport, nuclear envelope breakdown, apoptosis, transport of centrosomal proteins, mitotic spindle assembly, virus transport, kinetochore functions, and movement of signaling and spindle checkpoint proteins. Some complexes participate in intraflagellar transport. Subunits associated with the dynein heavy chain mediate association between dynein heavy chain and cargoes, and may include light chains and light intermediate chains.
5869	dynactin complex	C	A 20S multiprotein assembly of total mass about 1.2 MDa that activates dynein-based activity in vivo. A large structural component of the complex is an actin-like 40 nm filament composed of actin-related protein, to which other components attach.
5870	actin capping protein of dynactin complex	C	A heterodimer consisting of alpha and beta subunits that binds to and caps the barbed ends of actin filaments, nucleates the polymerization of actin monomers but does not sever actin filaments, and which is a part of the dynactin complex.
5871	kinesin complex	C	Any complex that includes a dimer of molecules from the kinesin superfamily, a group of related proteins that contain an extended region of predicted alpha-helical coiled coil in the main chain that likely produces dimerization. The native complexes of several kinesin family members have also been shown to contain additional peptides, often designated light chains as all of the noncatalytic subunits that are currently known are smaller than the chain that contains the motor unit. Kinesin complexes generally possess a force-generating enzymatic activity, or motor, which converts the free energy of the gamma phosphate bond of ATP into mechanical work.
5872	minus-end kinesin complex	C	Any complex that includes a dimer of molecules from the kinesin superfamily and any associated proteins, and moves towards the minus end of a microtubule.
5873	plus-end kinesin complex	C	Any complex that includes a dimer of molecules from the kinesin superfamily and any associated proteins, and moves towards the plus end of a microtubule.
5874	microtubule	C	Any of the long, generally straight, hollow tubes of internal diameter 12-15 nm and external diameter 24 nm found in a wide variety of eukaryotic cells; each consists (usually) of 13 protofilaments of polymeric tubulin, staggered in such a manner that the tubulin monomers are arranged in a helical pattern on the microtubular surface, and with the alpha/beta axes of the tubulin subunits parallel to the long axis of the tubule; exist in equilibrium with pool of tubulin monomers and can be rapidly assembled or disassembled in response to physiological stimuli; concerned with force generation, e.g. in the spindle.
5875	microtubule associated complex	C	Any multimeric complex connected to a microtubule.
5876	spindle microtubule	C	Any microtubule that is part of a mitotic or meiotic spindle; anchored at one spindle pole.
5879	axonemal microtubule	C	A microtubule in the axoneme of a eukaryotic cilium or flagellum; an axoneme contains nine modified doublet microtubules, which may or may not surround a pair of single microtubules.
5880	nuclear microtubule	C	Any microtubule in the nucleus of a cell.
5881	cytoplasmic microtubule	C	Any microtubule in the cytoplasm of a cell.
5882	intermediate filament	C	A cytoskeletal structure that forms a distinct elongated structure, characteristically 10 nm in diameter, that occurs in the cytoplasm of eukaryotic cells. Intermediate filaments form a fibrous system, composed of chemically heterogeneous subunits and involved in mechanically integrating the various components of the cytoplasmic space. Intermediate filaments may be divided into five chemically distinct classes: Type I, acidic keratins; Type II, basic keratins; Type III, including desmin, vimentin and others; Type IV, neurofilaments and related filaments; and Type V, lamins.
5883	neurofilament	C	A type of intermediate filament found in the core of neuronal axons. Neurofilaments are heteropolymers composed of three type IV polypeptides: NF-L, NF-M, and NF-H (for low, middle, and high molecular weight). Neurofilaments are responsible for the radial growth of an axon and determine axonal diameter.
5884	actin filament	C	A filamentous structure formed of a two-stranded helical polymer of the protein actin and associated proteins. Actin filaments are a major component of the contractile apparatus of skeletal muscle and the microfilaments of the cytoskeleton of eukaryotic cells. The filaments, comprising polymerized globular actin molecules, appear as flexible structures with a diameter of 5-9 nm. They are organized into a variety of linear bundles, two-dimensional networks, and three dimensional gels. In the cytoskeleton they are most highly concentrated in the cortex of the cell just beneath the plasma membrane.
5885	Arp2/3 protein complex	C	A stable protein complex that contains two actin-related proteins, Arp2 and Arp3, and five novel proteins (ARPC1-5), and functions in the nucleation of branched actin filaments.
5886	plasma membrane	C	The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
5887	integral component of plasma membrane	C	The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
5889	hydrogen:potassium-exchanging ATPase complex	C	A protein complex that possesses hydrogen:potassium-exchanging ATPase activity; characterized in animal cells, where it maintains ionic gradients of K+ at the expense of ATP hydrolysis; The complex contains two obligatory subunits, the catalytic alpha subunit and a glycosylated beta subunit; two additional subunits, gamma and channel-inducing factor (CHIF), may also be present.
5890	sodium:potassium-exchanging ATPase complex	C	Sodium:potassium-exchanging ATPases are tetrameric proteins, consisting of two large alpha subunits and two smaller beta subunits. The alpha subunits bear the active site and penetrate the membrane, while the beta subunits carry oligosaccharide groups and face the cell exterior.
5891	voltage-gated calcium channel complex	C	A protein complex that forms a transmembrane channel through which calcium ions may pass in response to changes in membrane potential.
5892	acetylcholine-gated channel complex	C	A homo- or hetero-pentameric protein complex that forms a transmembrane channel through which ions may pass in response to acetylcholine binding.
5893	interleukin-2 receptor complex	C	A protein complex that binds interleukin-2; comprises alpha, beta, and gamma subunits.
5894	interleukin-3 receptor complex	C	A protein complex that binds interleukin-3; comprises an alpha and a beta subunit. The alpha chain is specific to the interleukin-3 receptor, whereas the beta chain is shared with the receptors for granulocyte-macrophage colony-stimulating factor and interleukin-5.
5895	interleukin-5 receptor complex	C	A protein complex that binds interleukin-3; comprises an alpha and a beta subunit. The alpha chain is specific to the interleukin-5 receptor, whereas the beta chain is shared with the receptors for granulocyte-macrophage colony-stimulating factor and interleukin-3.
5896	interleukin-6 receptor complex	C	A hexameric protein complex consisting of two molecules each of interleukin-6, interleukin-6 receptor alpha chain, and gp-130.
5897	interleukin-9 receptor complex	C	A protein complex that binds interleukin-9; comprises an alpha and a beta subunit. The alpha chain is specific to the interleukin-9 receptor, whereas the beta chain is shared with the receptors for several other interleukins.
5898	interleukin-13 receptor complex	C	A protein complex that binds interleukin-13; consists of two chains, interleukin-13 receptor alpha1 chain and interleukin-4 receptor alpha chain.
5899	insulin receptor complex	C	A disulfide-bonded, heterotetrameric receptor complex. The alpha chains are entirely extracellular, while each beta chain has one transmembrane domain. The ligand binds to the alpha subunit extracellular domain and the kinase is associated with the beta subunit intracellular domain.
5900	oncostatin-M receptor complex	C	A heterodimeric receptor for the cytokine oncostatin-M (OSM). In humans the receptor complex is made up of the gene products gp130 and OSMR-beta.
5901	caveola	C	A membrane raft that forms small pit, depression, or invagination that communicates with the outside of a cell and extends inward, indenting the cytoplasm and the cell membrane. Examples include flask-shaped invaginations of the plasma membrane in adipocytes associated with caveolin proteins, and minute pits or incuppings of the cell membrane formed during pinocytosis. Caveolae may be pinched off to form free vesicles within the cytoplasm.
5902	microvillus	C	Thin cylindrical membrane-covered projections on the surface of an animal cell containing a core bundle of actin filaments. Present in especially large numbers on the absorptive surface of intestinal cells.
5903	brush border	C	The dense covering of microvilli on the apical surface of a epithelial cells in tissues such as the intestine, kidney, and choroid plexus; the microvilli aid absorption by increasing the surface area of the cell.
5905	clathrin-coated pit	C	A part of the endomembrane system in the form of an invagination of a membrane upon which a clathrin coat forms, and that can be converted by vesicle budding into a clathrin-coated vesicle. Coated pits form on the plasma membrane, where they are involved in receptor-mediated selective transport of many proteins and other macromolecules across the cell membrane, in the trans-Golgi network, and on some endosomes.
5911	cell-cell junction	C	A cell junction that forms a connection between two or more cells in a multicellular organism; excludes direct cytoplasmic junctions such as ring canals.
5912	adherens junction	C	A cell junction at which anchoring proteins (cadherins or integrins) extend through the plasma membrane and are attached to actin filaments.
5913	cell-cell adherens junction	C	An adherens junction which connects a cell to another cell.
5914	spot adherens junction	C	A small cell-cell adherens junction assembled during the cellularization stage of insect embyrogenesis; spot adherens junctions later fuse to form the zonula adherens.
5915	zonula adherens	C	A cell-cell adherens junction which forms a continuous belt near the apex of epithelial cells.
5916	fascia adherens	C	A cell-cell adherens junction that contains the transmembrane protein N-cadherin, which interacts with identical molecules from neighboring cells to form a tight mechanical intercellular link; forms a large portion of the intercalated disc, the structure at which myofibrils terminate in cardiomyocytes.
5917	nephrocyte diaphragm	C	A specialized cell-cell junction found between nephrocytes of the insect kidney, which is adapted for filtration of hemolymph. The insect nephrocyte is anatomically and functionally similar to the glomerular podocyte of vertebrates.
5918	septate junction	C	A cell-cell junction that forms a continuous band around each cell in an epithelium; within the septate junction the membranes of adjacent cells maintain a constant distance of approximately 15 nm; found in invertebrates.
5919	pleated septate junction	C	A septate junction in which regular arrays of electron-dense septae span the intermembrane space.
5920	smooth septate junction	C	A septate junction that lacks the regular arrays of electron-dense septae found in pleated septate junctions.
5921	gap junction	C	A cell-cell junction composed of pannexins or innexins and connexins, two different families of channel-forming proteins.
5922	connexin complex	C	An assembly of six molecules of connexin, made in the Golgi apparatus and subsequently transported to the plasma membrane, where docking of two connexons on apposed plasma membranes across the extracellular space forms a gap junction.
5923	bicellular tight junction	C	An occluding cell-cell junction that is composed of a branching network of sealing strands that completely encircles the apical end of each cell in an epithelial sheet; the outer leaflets of the two interacting plasma membranes are seen to be tightly apposed where sealing strands are present. Each sealing strand is composed of a long row of transmembrane adhesion proteins embedded in each of the two interacting plasma membranes.
5924	cell-substrate adherens junction	C	An adherens junction which connects a cell to the extracellular matrix.
5925	focal adhesion	C	Small region on the surface of a cell that anchors the cell to the extracellular matrix and that forms a point of termination of actin filaments.
5926	connecting hemi-adherens junction	C	A cell-substrate adherens junction, also known as a hemiadherens junction (HAJ) that forms one of a pair of junctions in opposing cells that are separated by only 30-40nm, with a thin line of extracellular electron-dense material in between; found where muscles attach to epidermal cells directly (in insects).
5927	muscle tendon junction	C	A cell-substrate junction found at the terminal anchorage site of skeletal muscle cells to tendons.
5928	apical hemi-adherens junction	C	A cell-substrate adherens junction found in the apical region of a cell, such as those found in cuticle-secreting epithelia, which connect the apical membrane to the cuticle.
5929	cilium	C	A specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface and of some cytoplasmic parts. Each cilium is largely bounded by an extrusion of the cytoplasmic (plasma) membrane, and contains a regular longitudinal array of microtubules, anchored to a basal body.
5930	axoneme	C	The bundle of microtubules and associated proteins that forms the core of cilia (also called flagella) in eukaryotic cells and is responsible for their movements.
5931	axonemal nexin link	C	A protein complex found in the axoneme of eukaryotic cilia and flagella. It forms interconnections between the microtubule outer doublets that surround the inner central pair of microtubules.
5933	cellular bud	C	A protuberance from a cell of an organism that reproduces by budding, which will grow larger and become a separate daughter cell after nuclear division, cytokinesis, and cell wall formation (when appropriate). The daughter cell may completely separate from the mother cell, or the mother and daughter cells may remain associated.
5934	cellular bud tip	C	The end of a cellular bud distal to the site of attachment to the mother cell.
5935	cellular bud neck	C	The constriction between the mother cell and daughter cell (bud) in an organism that reproduces by budding.
5937	mating projection	C	The projection formed by unicellular fungi in response to mating pheromone.
5938	cell cortex	C	The region of a cell that lies just beneath the plasma membrane and often, but not always, contains a network of actin filaments and associated proteins.
5940	septin ring	C	A tight ring-shaped structure that forms in the division plane at the site of cytokinesis; composed of members of the conserved family of filament-forming proteins called septins as well as septin-associated proteins. This type of septin structure is observed at the bud neck of budding fungal cells, at the site of cell division in animal cells, at the junction between the mother cell and a pseudohyphal projection, and also within hyphae of filamentous fungi at sites where a septum will form.
5942	phosphatidylinositol 3-kinase complex	C	A protein complex capable of phosphatidylinositol 3-kinase activity and containing subunits of any phosphatidylinositol 3-kinase (PI3K) enzyme. These complexes are divided in three classes (called I, II and III) that differ for their presence across taxonomic groups and for the type of their constituents. Catalytic subunits of phosphatidylinositol 3-kinase enzymes are present in all 3 classes; regulatory subunits of phosphatidylinositol 3-kinase enzymes are present in classes I and III; adaptor proteins have been observed in class II complexes and may be present in other classes too.
5943	phosphatidylinositol 3-kinase complex, class IA	C	A class I phosphatidylinositol 3-kinase complex that possesses 1-phosphatidylinositol-4-phosphate 3-kinase activity; comprises a catalytic class IA phosphoinositide 3-kinase (PI3K) subunit and an associated SH2 domain-containing regulatory subunit that is a member of a family of related proteins often called p85 proteins. Through the interaction with the SH2-containing adaptor subunits, Class IA PI3K catalytic subunits are linked to tyrosine kinase signaling pathways.
5944	phosphatidylinositol 3-kinase complex, class IB	C	A class I phosphatidylinositol 3-kinase complex that possesses 1-phosphatidylinositol-4-phosphate 3-kinase activity; comprises a catalytic class IB phosphoinositide 3-kinase (PI3K) subunit and an associated regulatory subunit that is larger than, and unrelated to, the p85 proteins present in class IA complexes. Class IB PI3Ks are stimulated by G-proteins and do not interact with the SH2-domain containing adaptors that bind to Class IA PI3Ks.
5945	6-phosphofructokinase complex	C	A protein complex that possesses 6-phosphofructokinase activity; homodimeric, homooctameric, and allosteric homotetrameric forms are known.
5946	alpha,alpha-trehalose-phosphate synthase complex (UDP-forming)	C	A protein complex that possesses alpha,alpha-trehalose-phosphate synthase (UDP-forming) and trehalose-phosphatase activities, and thus catalyzes two reactions in trehalose biosynthesis. In the complex identified in Saccharomyces, Tps1p has alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity, Tps2p has trehalose 6-phosphate phosphatase activity; Tps3p is a regulatory subunit, and an additional subunit, Tsl1p, may be present.
5947	mitochondrial alpha-ketoglutarate dehydrogenase complex	C	Mitochondrial complex that possesses alpha-ketoglutarate dehydrogenase activity.
5948	acetolactate synthase complex	C	A dimeric (a large and a small chain) or tetrameric (two large and two small chains) enzyme complex. Catalyzes the formation of acetolactate from pyruvate.
5950	anthranilate synthase complex	C	A heterotetrameric enzyme complex made up of two components I and two components II. Catalyzes the formation of anthranilate, pyruvate and L-glutamate from chorismate and L-glutamine.
5951	carbamoyl-phosphate synthase complex	C	A protein complex that catalyzes the formation of carbamoyl phosphate; comprises a small subunit that binds and cleaves glutamine, and a large subunit that accepts the ammonia group cleaved from glutamine, binds all of the remaining substrates and effectors, and carries out all of the other catalytic events.
5952	cAMP-dependent protein kinase complex	C	An enzyme complex, composed of regulatory and catalytic subunits, that catalyzes protein phosphorylation. Inactive forms of the enzyme have two regulatory chains and two catalytic chains; activation by cAMP produces two active catalytic monomers and a regulatory dimer.
5953	CAAX-protein geranylgeranyltransferase complex	C	A heterodimeric enzyme, composed of an alpha and a beta subunit. Participates in the post-translational C-terminal modification of several small GTPases, allowing their targeting to the membrane.
5954	calcium- and calmodulin-dependent protein kinase complex	C	An enzyme complex which in eukaryotes is composed of four different chains: alpha, beta, gamma, and delta. The different isoforms assemble into homo- or heteromultimeric holoenzymes composed of 8 to 12 subunits. Catalyzes the phosphorylation of proteins to O-phosphoproteins.
5955	calcineurin complex	C	A heterodimeric calcium ion and calmodulin dependent protein phosphatase composed of catalytic and regulatory subunits; the regulatory subunit is very similar in sequence to calmodulin.
5956	protein kinase CK2 complex	C	A protein complex that possesses protein serine/threonine kinase activity, and contains two catalytic alpha subunits and two regulatory beta subunits. Protein kinase CK2 complexes are found in nearly every subcellular compartment, and can phosphorylate many protein substrates in addition to casein.
5958	DNA-dependent protein kinase-DNA ligase 4 complex	C	A large protein complex which is involved in the repair of DNA double-strand breaks and, in mammals, V(D)J recombination events. It consists of the DNA-dependent protein kinase catalytic subunit (DNA-PKcs), the DNA end-binding heterodimer Ku, the nuclear phosphoprotein XRCC4 or a homolog thereof, and DNA ligase IV.
5960	glycine cleavage complex	C	A protein complex that catalyzes the reversible oxidation of glycine. In E. coli, it has four components: dihydrolipoamide dehydrogenase, glycine dehydrogenase (decarboxylating), lipoyl-GcvH-protein and aminomethyltransferase, also known as L, P, H, and T.
5962	mitochondrial isocitrate dehydrogenase complex (NAD+)	C	Mitochondrial complex that possesses isocitrate dehydrogenase (NAD+) activity.
5963	magnesium-dependent protein serine/threonine phosphatase complex	C	An enzyme complex that catalyzes the removal of serine- or threonine-bound phosphate groups from a wide range of phosphoproteins, including a number of enzymes that have been phosphorylated under the action of a kinase.
5964	phosphorylase kinase complex	C	An enzyme complex that catalyzes the phosphorylation of phosphorylase b to form phosphorylase a.
5965	protein farnesyltransferase complex	C	A protein complex that possesses protein farnesyltransferase activity.
5966	cyclic-nucleotide phosphodiesterase complex	C	An enzyme complex that catalyzes the hydrolysis of bonds in a cyclic nucleotide.
5967	mitochondrial pyruvate dehydrogenase complex	C	Complex that carries out the oxidative decarboxylation of pyruvate to form acetyl-CoA in eukaryotes; includes subunits possessing three catalytic activities: pyruvate dehydrogenase (E1), dihydrolipoamide S-acetyltransferase (E2), and dihydrolipoamide dehydrogenase (E3). The This Eukaryotic form usually contains more subunits than its bacterial counterpart; for example, one known complex contains 30 E1 dimers, 60 E2 monomers, and 6 E3 dimers as well as a few copies of pyruvate dehydrogenase kinase and pyruvate dehydrogenase phosphatase.
5968	Rab-protein geranylgeranyltransferase complex	C	A heterodimeric enzyme complex, which in mammals is composed of an alpha and a beta subunit, and which associates with an accessory protein Rep (Rab escort protein). Catalyzes of the transfer of a geranyl-geranyl group from geranylgeranyl pyrophosphate to a Rab protein.
5969	serine-pyruvate aminotransferase complex	C	An enzyme complex that catalyzes the formation of hydroxypyruvate and alanine from serine and pyruvate.
5971	ribonucleoside-diphosphate reductase complex	C	An enzyme complex composed of 2-4 or more subunits, which usually contains nonheme iron and requires ATP for catalysis. Catalyzes the formation of 2'-deoxyribonucleoside diphosphate from ribonucleoside diphosphate, using either thioredoxin disulfide or glutaredoxin disulfide as an acceptor.
5975	carbohydrate metabolic process	P	The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y. Includes the formation of carbohydrate derivatives by the addition of a carbohydrate residue to another molecule.
5976	polysaccharide metabolic process	P	The chemical reactions and pathways involving a polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically.
5977	glycogen metabolic process	P	The chemical reactions and pathways involving glycogen, a polydisperse, highly branched glucan composed of chains of D-glucose residues in alpha-(1->4) glycosidic linkage, joined together by alpha-(1->6) glycosidic linkages.
5978	glycogen biosynthetic process	P	The chemical reactions and pathways resulting in the formation of glycogen, a polydisperse, highly branched glucan composed of chains of D-glucose residues.
5979	regulation of glycogen biosynthetic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glycogen.
5980	glycogen catabolic process	P	The chemical reactions and pathways resulting in the breakdown of glycogen, a polydisperse, highly branched glucan composed of chains of D-glucose residues.
5981	regulation of glycogen catabolic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glycogen.
5982	starch metabolic process	P	The chemical reactions and pathways involving starch, the most important reserve polysaccharide in plants. It is a glucan consisting of two components, amylose and amylopectin, which are both glucose homopolymers. Starch is synthesized as a temporary storage form of carbon and can be catabolized to produce sucrose.
5983	starch catabolic process	P	The chemical reactions and pathways resulting in the breakdown of starch, the most important reserve polysaccharide in plants.
5984	disaccharide metabolic process	P	The chemical reactions and pathways involving any disaccharide, sugars composed of two monosaccharide units.
5985	sucrose metabolic process	P	The chemical reactions and pathways involving sucrose, the disaccharide fructofuranosyl-glucopyranoside.
5986	sucrose biosynthetic process	P	The chemical reactions and pathways resulting in the formation of sucrose, the disaccharide fructofuranosyl-glucopyranoside.
5987	sucrose catabolic process	P	The chemical reactions and pathways resulting in the breakdown of sucrose, the disaccharide fructofuranosyl-glucopyranoside.
5988	lactose metabolic process	P	The chemical reactions and pathways involving lactose, the disaccharide galactopyranosyl-glucose.
5989	lactose biosynthetic process	P	The chemical reactions and pathways resulting in the formation of lactose, the disaccharide galactopyranosyl-glucose.
5990	lactose catabolic process	P	The chemical reactions and pathways resulting in the breakdown of lactose, the disaccharide galactopyranosyl-glucose.
5991	trehalose metabolic process	P	The chemical reactions and pathways involving trehalose, a disaccharide isomeric with sucrose and obtained from certain lichens and fungi.
5992	trehalose biosynthetic process	P	The chemical reactions and pathways resulting in the formation of trehalose, a disaccharide isomeric with sucrose and obtained from certain lichens and fungi.
5993	trehalose catabolic process	P	The chemical reactions and pathways resulting in the breakdown of trehalose, a disaccharide isomeric with sucrose and obtained from certain lichens and fungi.
5994	melibiose metabolic process	P	The chemical reactions and pathways involving melibiose, the disaccharide 6-O-alpha-D-galactopyranosyl-D-glucose.
5995	melibiose catabolic process	P	The chemical reactions and pathways resulting in the breakdown of melibiose, the disaccharide 6-O-alpha-D-galactopyranosyl-D-glucose.
5996	monosaccharide metabolic process	P	The chemical reactions and pathways involving monosaccharides, the simplest carbohydrates. They are polyhydric alcohols containing either an aldehyde or a keto group and between three to ten or more carbon atoms. They form the constitutional repeating units of oligo- and polysaccharides.
5997	xylulose metabolic process	P	The chemical reactions and pathways involving xylulose, the ketopentose threo-2-pentulose.
5998	xylulose catabolic process	P	The chemical reactions and pathways resulting in the breakdown of xylulose, the ketopentose threo-2-pentulose.
5999	xylulose biosynthetic process	P	The chemical reactions and pathways resulting in the formation of xylulose, the ketopentose threo-2-pentulose.
6000	fructose metabolic process	P	The chemical reactions and pathways involving fructose, the ketohexose arabino-2-hexulose. Fructose exists in a open chain form or as a ring compound. D-fructose is the sweetest of the sugars and is found free in a large number of fruits and honey.
6001	fructose catabolic process	P	The chemical reactions and pathways resulting in the breakdown of fructose, the ketohexose arabino-2-hexulose.
6002	fructose 6-phosphate metabolic process	P	The chemical reactions and pathways involving fructose 6-phosphate, also known as F6P. The D-enantiomer is an important intermediate in glycolysis, gluconeogenesis, and fructose metabolism.
6003	fructose 2,6-bisphosphate metabolic process	P	The chemical reactions and pathways involving fructose 2,6-bisphosphate. The D enantiomer is an important regulator of the glycolytic and gluconeogenic pathways. It inhibits fructose 1,6-bisphosphatase and activates phosphofructokinase.
6004	fucose metabolic process	P	The chemical reactions and pathways involving fucose, or 6-deoxygalactose, which has two enantiomers, D-fucose and L-fucose.
6005	L-fucose biosynthetic process	P	The chemical reactions and pathways resulting in the formation of L-fucose (6-deoxy-L-galactose).
6006	glucose metabolic process	P	The chemical reactions and pathways involving glucose, the aldohexose gluco-hexose. D-glucose is dextrorotatory and is sometimes known as dextrose; it is an important source of energy for living organisms and is found free as well as combined in homo- and hetero-oligosaccharides and polysaccharides.
6007	glucose catabolic process	P	The chemical reactions and pathways resulting in the breakdown of glucose, the aldohexose gluco-hexose.
6009	glucose 1-phosphate phosphorylation	P	The process of introducing a phosphate group into glucose 1-phosphate to produce glucose bisphosphate.
6011	UDP-glucose metabolic process	P	The chemical reactions and pathways involving UDP-glucose, uridinediphosphoglucose, a substance composed of glucose in glycosidic linkage with uridine diphosphate.
6012	galactose metabolic process	P	The chemical reactions and pathways involving galactose, the aldohexose galacto-hexose. D-galactose is widely distributed in combined form in plants, animals and microorganisms as a constituent of oligo- and polysaccharides; it also occurs in galactolipids and as its glucoside in lactose and melibiose.
6013	mannose metabolic process	P	The chemical reactions and pathways involving mannose, the aldohexose manno-hexose, the C-2 epimer of glucose. The D-(+)-form is widely distributed in mannans and hemicelluloses and is of major importance in the core oligosaccharide of N-linked oligosaccharides of glycoproteins.
6014	D-ribose metabolic process	P	The chemical reactions and pathways involving D-ribose (ribo-pentose). As beta-D-ribofuranose, D-ribose forms the glycose group of all ribonucleosides, ribonucleotides and ribonucleic acids, and also of ribose phosphates, various glycosides, some coenzymes and some forms of vitamin B12.
6015	5-phosphoribose 1-diphosphate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of 5-phosphoribose 1-diphosphate, also known as 5-phosphoribosyl-1-pyrophosphate.
6016	2-deoxyribose 1-phosphate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of 2-deoxyribose 1-phosphate, the phosphorylated sugar 1-phospho-2-deoxyribose.
6017	deoxyribose 1,5-bisphosphate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of deoxyribose 1,5-bisphosphate, the diphosphorylated sugar 1,5-diphospho-2-deoxyribose.
6018	2-deoxyribose 1-phosphate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of deoxyribose 1-phosphate, the phosphorylated sugar 1-phospho-2-deoxyribose.
6019	deoxyribose 5-phosphate phosphorylation	P	The process of introducing a phosphate group into deoxyribose 5-phosphate to produce deoxyribose bisphosphate.
6020	inositol metabolic process	P	The chemical reactions and pathways involving inositol, 1,2,3,4,5,6-cyclohexanehexol, a growth factor for animals and microorganisms.
6021	inositol biosynthetic process	P	The chemical reactions and pathways resulting in the formation of inositol, 1,2,3,4,5,6-cyclohexanehexol, a growth factor for animals and microorganisms.
6022	aminoglycan metabolic process	P	The chemical reactions and pathways involving aminoglycans, any polymer containing amino groups that consists of more than about 10 monosaccharide residues joined to each other by glycosidic linkages.
6023	aminoglycan biosynthetic process	P	The chemical reactions and pathways resulting in the formation of aminoglycans, any polymer containing amino groups that consists of more than about 10 monosaccharide residues joined to each other by glycosidic linkages.
6024	glycosaminoglycan biosynthetic process	P	The chemical reactions and pathways resulting in the formation of glycosaminoglycans, any of a group of polysaccharides that contain amino sugars.
6025	galactosaminoglycan biosynthetic process	P	The chemical reactions and pathways resulting in the formation of galactosaminoglycans, any of a group of polysaccharides that contain amino sugars derived from the galactose.
6026	aminoglycan catabolic process	P	The chemical reactions and pathways resulting in the breakdown of aminoglycans, any polymer containing amino groups that consists of more than about 10 monosaccharide residues joined to each other by glycosidic linkages.
6027	glycosaminoglycan catabolic process	P	The chemical reactions and pathways resulting in the breakdown of glycosaminoglycans, any one of a group of polysaccharides that contain amino sugars.
6028	galactosaminoglycan catabolic process	P	The chemical reactions and pathways resulting in the breakdown of galactosaminoglycans, any of a group of polysaccharides that contain amino sugars derived from the galactose.
6029	proteoglycan metabolic process	P	The chemical reactions and pathways involving proteoglycans, any glycoprotein in which the carbohydrate units are glycosaminoglycans.
6030	chitin metabolic process	P	The chemical reactions and pathways involving chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues.
6031	chitin biosynthetic process	P	The chemical reactions and pathways resulting in the formation of chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues.
6032	chitin catabolic process	P	The chemical reactions and pathways resulting in the breakdown of chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues.
6033	chitin localization	P	A process in which chitin is transported to, or maintained in, a specific location.
6034	cuticle chitin metabolic process	P	The chemical reactions and pathways involving cuticle chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues, found in cuticles.
6035	cuticle chitin biosynthetic process	P	The chemical reactions and pathways resulting in the formation of cuticle chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues, found in cuticles.
6036	cuticle chitin catabolic process	P	The chemical reactions and pathways resulting in the breakdown of cuticle chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues, found in cuticles.
6037	cell wall chitin metabolic process	P	The chemical reactions and pathways involving cell wall chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues, found in the walls of cells.
6038	cell wall chitin biosynthetic process	P	The chemical reactions and pathways resulting in the formation of cell wall chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues, found in the walls of cells.
6039	cell wall chitin catabolic process	P	The chemical reactions and pathways resulting in the breakdown of cell wall chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues, found in the walls of cells.
6040	amino sugar metabolic process	P	The chemical reactions and pathways involving any amino sugar, sugars containing an amino group in place of a hydroxyl group.
6041	glucosamine metabolic process	P	The chemical reactions and pathways involving glucosamine (2-amino-2-deoxyglucopyranose), an aminodeoxysugar that occurs in combined form in chitin.
6042	glucosamine biosynthetic process	P	The chemical reactions and pathways resulting in the formation of glucosamine (2-amino-2-deoxyglucopyranose), an aminodeoxysugar that occurs in combined form in chitin.
6043	glucosamine catabolic process	P	The chemical reactions and pathways resulting in the breakdown of glucosamine (2-amino-2-deoxyglucopyranose), an aminodeoxysugar that occurs in combined form in chitin.
6044	N-acetylglucosamine metabolic process	P	The chemical reactions and pathways involving N-acetylglucosamine. The D isomer is a common structural unit of glycoproteins in plants, bacteria and animals; it is often the terminal sugar of an oligosaccharide group of a glycoprotein.
6045	N-acetylglucosamine biosynthetic process	P	The chemical reactions and pathways resulting in the formation of N-acetylglucosamine. The D isomer is a common structural unit of glycoproteins in plants, bacteria and animals; it is often the terminal sugar of an oligosaccharide group of a glycoprotein.
6046	N-acetylglucosamine catabolic process	P	The chemical reactions and pathways resulting in the breakdown of N-acetylglucosamine. The D isomer is a common structural unit of glycoproteins in plants, bacteria and animals; it is often the terminal sugar of an oligosaccharide group of a glycoprotein.
6047	UDP-N-acetylglucosamine metabolic process	P	The chemical reactions and pathways involving UDP-N-acetylglucosamine, a substance composed of N-acetylglucosamine, a common structural unit of oligosaccharides, in glycosidic linkage with uridine diphosphate.
6048	UDP-N-acetylglucosamine biosynthetic process	P	The chemical reactions and pathways resulting in the formation of UDP-N-acetylglucosamine, a substance composed of N-acetylglucosamine, a common structural unit of oligosaccharides, in glycosidic linkage with uridine diphosphate.
6049	UDP-N-acetylglucosamine catabolic process	P	The chemical reactions and pathways resulting in the breakdown of UDP-N-acetylglucosamine, a substance composed of N-acetylglucosamine, a common structural unit of oligosaccharides, in glycosidic linkage with uridine diphosphate.
6050	mannosamine metabolic process	P	The chemical reactions and pathways involving mannosomine, 2-amino-2-deoxymannose; the D-isomer is a constituent of neuraminic acids as well as mucolipids and mucoproteins.
6051	N-acetylmannosamine metabolic process	P	The chemical reactions and pathways involving N-acetylmannosamine, the acetylated derivative of mannosamine, 2-amino-2-deoxymannose.
6052	N-acetylmannosamine biosynthetic process	P	The chemical reactions and pathways resulting in the formation of N-acetylmannosamine, the acetylated derivative of mannosamine, 2-amino-2-deoxymannose.
6053	N-acetylmannosamine catabolic process	P	The chemical reactions and pathways resulting in the breakdown of N-acetylmannosamine, the acetylated derivative of mannosamine, 2-amino-2-deoxymannose.
6054	N-acetylneuraminate metabolic process	P	The chemical reactions and pathways involving N-acetylneuraminate, the anion of 5-(acetylamino)-3,5-dideoxy-D-glycero-D-galacto-non-3-ulosonic acid.
6055	CMP-N-acetylneuraminate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of CMP-N-acetylneuraminate, a substance composed of 5-(acetylamino)-3,5-dideoxy-D-glycero-D-galacto-non-3-ulosonic acid in glycosidic linkage with cytidine monophosphate.
6056	mannoprotein metabolic process	P	The chemical reactions and pathways involving mannoproteins, any protein that contains covalently bound mannose residues.
6057	mannoprotein biosynthetic process	P	The chemical reactions and pathways resulting in the formation of mannoproteins, any protein that contains covalently bound mannose residues.
6058	mannoprotein catabolic process	P	The chemical reactions and pathways resulting in the breakdown of mannoproteins, any protein that contains covalently bound mannose residues.
6059	hexitol metabolic process	P	The chemical reactions and pathways involving hexitols, any alditol with a chain of six carbon atoms in the molecule.
6060	sorbitol metabolic process	P	The chemical reactions and pathways involving sorbitol (D-glucitol), one of the ten stereoisomeric hexitols. It can be derived from glucose by reduction of the aldehyde group.
6061	sorbitol biosynthetic process	P	The chemical reactions and pathways resulting in the formation of sorbitol (D-glucitol), one of the ten stereoisomeric hexitols. It can be derived from glucose by reduction of the aldehyde group.
6062	sorbitol catabolic process	P	The chemical reactions and pathways resulting in the breakdown of sorbitol (D-glucitol), one of the ten stereoisomeric hexitols. It can be derived from glucose by reduction of the aldehyde group.
6063	uronic acid metabolic process	P	The chemical reactions and pathways involving uronic acid, any monocarboxylic acid formally derived by oxidizing to a carboxyl group the terminal hydroxymethylene group of either an aldose with four or more carbon atoms in the molecule, or of any glycoside derived from such an aldose.
6064	glucuronate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of glucuronate, any salt or ester of glucuronic acid.
6065	UDP-glucuronate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of UDP-glucuronate, a substance composed of glucuronic acid in glycosidic linkage with uridine diphosphate.
6066	alcohol metabolic process	P	The chemical reactions and pathways involving alcohols, any of a class of compounds containing one or more hydroxyl groups attached to a saturated carbon atom.
6067	ethanol metabolic process	P	The chemical reactions and pathways involving ethanol, CH3-CH2-OH, a colorless, water-miscible, flammable liquid produced by alcoholic fermentation.
6068	ethanol catabolic process	P	The chemical reactions and pathways resulting in the breakdown of ethanol, CH3-CH2-OH, a colorless, water-miscible, flammable liquid produced by alcoholic fermentation.
6069	ethanol oxidation	P	An ethanol metabolic process in which ethanol is converted to acetyl-CoA via acetaldehyde and acetate.
6070	octanol metabolic process	P	The chemical reactions and pathways involving octanol, the 8-carbon alcohol with the formula C8H17OH.
6071	glycerol metabolic process	P	The chemical reactions and pathways involving glycerol, 1,2,3-propanetriol, a sweet, hygroscopic, viscous liquid, widely distributed in nature as a constituent of many lipids.
6072	glycerol-3-phosphate metabolic process	P	The chemical reactions and pathways involving glycerol-3-phosphate, a phosphoric monoester of glycerol.
6073	cellular glucan metabolic process	P	The chemical reactions and pathways involving glucans, polysaccharides consisting only of glucose residues, occurring at the level of an individual cell.
6074	(1->3)-beta-D-glucan metabolic process	P	The chemical reactions and pathways involving (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D-glucosidic bonds.
6075	(1->3)-beta-D-glucan biosynthetic process	P	The chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D-glucosidic bonds.
6076	(1->3)-beta-D-glucan catabolic process	P	The chemical reactions and pathways resulting in the breakdown of (1->3)-beta-D-glucans.
6077	(1->6)-beta-D-glucan metabolic process	P	The chemical reactions and pathways involving (1->6)-beta-D-glucans, compounds composed of glucose residues linked by (1->6)-beta-D-glucosidic bonds.
6078	(1->6)-beta-D-glucan biosynthetic process	P	The chemical reactions and pathways resulting in the formation of (1->6)-beta-D-glucans.
6079	(1->6)-beta-D-glucan catabolic process	P	The chemical reactions and pathways resulting in the breakdown of (1->6)-beta-D-glucans.
6080	substituted mannan metabolic process	P	The chemical reactions and pathways involving a mannan backbone composed of D-mannose unites, substituted with D-glucose and/or D-galactose units.
6081	cellular aldehyde metabolic process	P	The chemical reactions and pathways involving aldehydes, any organic compound with the formula R-CH=O, as carried out by individual cells.
6082	organic acid metabolic process	P	The chemical reactions and pathways involving organic acids, any acidic compound containing carbon in covalent linkage.
6083	acetate metabolic process	P	The chemical reactions and pathways involving acetate, the anion of acetic acid.
6084	acetyl-CoA metabolic process	P	The chemical reactions and pathways involving acetyl-CoA, a derivative of coenzyme A in which the sulfhydryl group is acetylated; it is a metabolite derived from several pathways (e.g. glycolysis, fatty acid oxidation, amino-acid catabolism) and is further metabolized by the tricarboxylic acid cycle. It is a key intermediate in lipid and terpenoid biosynthesis.
6085	acetyl-CoA biosynthetic process	P	The chemical reactions and pathways resulting in the formation of acetyl-CoA, a derivative of coenzyme A in which the sulfhydryl group is acetylated.
6086	acetyl-CoA biosynthetic process from pyruvate	P	The chemical reactions and pathways resulting in the formation of acetyl-CoA from pyruvate.
6089	lactate metabolic process	P	The chemical reactions and pathways involving lactate, the anion of lactic acid.
6090	pyruvate metabolic process	P	The chemical reactions and pathways involving pyruvate, 2-oxopropanoate.
6091	generation of precursor metabolites and energy	P	The chemical reactions and pathways resulting in the formation of precursor metabolites, substances from which energy is derived, and any process involved in the liberation of energy from these substances.
6094	gluconeogenesis	P	The formation of glucose from noncarbohydrate precursors, such as pyruvate, amino acids and glycerol.
6096	glycolytic process	P	The chemical reactions and pathways resulting in the breakdown of a carbohydrate into pyruvate, with the concomitant production of a small amount of ATP and the reduction of NAD(P) to NAD(P)H. Glycolysis begins with the metabolism of a carbohydrate to generate products that can enter the pathway and ends with the production of pyruvate. Pyruvate may be converted to acetyl-coenzyme A, ethanol, lactate, or other small molecules.
6097	glyoxylate cycle	P	A modification of the TCA cycle occurring in some plants and microorganisms, in which isocitrate is cleaved to glyoxylate and succinate. Glyoxylate can then react with acetyl-CoA to form malate.
6098	pentose-phosphate shunt	P	The glucose-6-phosphate catabolic process in which, coupled to NADPH synthesis, glucose-6-P is oxidized with the formation of carbon dioxide (CO2) and ribulose 5-phosphate; ribulose 5-P then enters a series of reactions interconverting sugar phosphates. The pentose phosphate pathway is a major source of reducing equivalents for biosynthesis reactions and is also important for the conversion of hexoses to pentoses.
6099	tricarboxylic acid cycle	P	A nearly universal metabolic pathway in which the acetyl group of acetyl coenzyme A is effectively oxidized to two CO2 and four pairs of electrons are transferred to coenzymes. The acetyl group combines with oxaloacetate to form citrate, which undergoes successive transformations to isocitrate, 2-oxoglutarate, succinyl-CoA, succinate, fumarate, malate, and oxaloacetate again, thus completing the cycle. In eukaryotes the tricarboxylic acid is confined to the mitochondria. See also glyoxylate cycle.
6101	citrate metabolic process	P	The chemical reactions and pathways involving citrate, 2-hydroxy-1,2,3-propanetricarboyxlate. Citrate is widely distributed in nature and is an important intermediate in the TCA cycle and the glyoxylate cycle.
6102	isocitrate metabolic process	P	The chemical reactions and pathways involving isocitrate, the anion of isocitric acid, 1-hydroxy-1,2,3-propanetricarboxylic acid. Isocitrate is an important intermediate in the TCA cycle and the glycoxylate cycle.
6103	2-oxoglutarate metabolic process	P	The chemical reactions and pathways involving oxoglutarate, the dianion of 2-oxoglutaric acid. It is a key constituent of the TCA cycle and a key intermediate in amino-acid metabolism.
6104	succinyl-CoA metabolic process	P	The chemical reactions and pathways involving succinyl-CoA, a compound composed of the monovalent acyl group 3-carboxypropanoyl, derived from succinic acid by loss of one OH group, linked to coenzyme A.
6105	succinate metabolic process	P	The chemical reactions and pathways involving succinate, also known as butanedioate or ethane dicarboxylate, the dianion of succinic acid. Succinate is an important intermediate in metabolism and a component of the TCA cycle.
6106	fumarate metabolic process	P	The chemical reactions and pathways involving fumarate, the anion of trans-1,2-ethenedicarboxylic acid, the diastereoisomer of maleate. It is a key intermediate in metabolism and is formed in the TCA cycle from succinate and converted into malate.
6107	oxaloacetate metabolic process	P	The chemical reactions and pathways involving oxaloacetate, the anion of oxobutanedioic acid, an important intermediate in metabolism, especially as a component of the TCA cycle.
6108	malate metabolic process	P	The chemical reactions and pathways involving malate, the anion of hydroxybutanedioic acid, a chiral hydroxydicarboxylic acid. The (+) enantiomer is an important intermediate in metabolism as a component of both the TCA cycle and the glyoxylate cycle.
6109	regulation of carbohydrate metabolic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving carbohydrates.
6110	regulation of glycolytic process	P	Any process that modulates the frequency, rate or extent of glycolysis.
6111	regulation of gluconeogenesis	P	Any process that modulates the frequency, rate or extent of gluconeogenesis, the formation of glucose from noncarbohydrate precursors, such as pyruvate, amino acids and glycerol.
6112	energy reserve metabolic process	P	The chemical reactions and pathways by which a cell derives energy from stored compounds such as fats or glycogen.
6113	fermentation	P	The anaerobic enzymatic conversion of organic compounds, especially carbohydrates, coupling the oxidation and reduction of NAD/H and the generation of adenosine triphosphate (ATP).
6114	glycerol biosynthetic process	P	The chemical reactions and pathways resulting in the formation of glycerol, 1,2,3-propanetriol, a sweet, hygroscopic, viscous liquid, widely distributed in nature as a constituent of many lipids.
6115	ethanol biosynthetic process	P	The chemical reactions and pathways resulting in the formation of ethanol, CH3-CH2-OH, a colorless, water-miscible, flammable liquid produced by alcoholic fermentation.
6116	NADH oxidation	P	A metabolic process that results in the oxidation of reduced nicotinamide adenine dinucleotide, NADH, to the oxidized form, NAD.
6117	acetaldehyde metabolic process	P	The chemical reactions and pathways involving acetaldehyde, a colorless, flammable liquid intermediate in the metabolism of alcohol.
6119	oxidative phosphorylation	P	The phosphorylation of ADP to ATP that accompanies the oxidation of a metabolite through the operation of the respiratory chain. Oxidation of compounds establishes a proton gradient across the membrane, providing the energy for ATP synthesis.
6120	mitochondrial electron transport, NADH to ubiquinone	P	The transfer of electrons from NADH to ubiquinone that occurs during oxidative phosphorylation, mediated by the multisubunit enzyme known as complex I.
6121	mitochondrial electron transport, succinate to ubiquinone	P	The transfer of electrons from succinate to ubiquinone that occurs during oxidative phosphorylation, mediated by the multisubunit enzyme known as complex II.
6122	mitochondrial electron transport, ubiquinol to cytochrome c	P	The transfer of electrons from ubiquinol to cytochrome c that occurs during oxidative phosphorylation, mediated by the multisubunit enzyme known as complex III.
6123	mitochondrial electron transport, cytochrome c to oxygen	P	The transfer of electrons from cytochrome c to oxygen that occurs during oxidative phosphorylation, mediated by the multisubunit enzyme known as complex IV.
6124	ferredoxin metabolic process	P	The chemical reactions and pathways involving ferredoxin, any simple, nonenzymatic iron-sulfur protein that is characterized by having equal numbers of atoms of iron and labile sulfur. Iron and sulfur atoms are present in one or two clusters of two or four atoms of each.
6127	glycerophosphate shuttle	P	The process of transferring reducing equivalents from the cytosol into the mitochondria; NADH is used to synthesise glycerol 3-phosphate in the cytosol; this compound is then transported into the mitochondria where it is converted to dihydroxyacetone phosphate (DHAP) using FAD; DHAP then returns to the cytosol to complete the cycle.
6139	nucleobase-containing compound metabolic process	P	Any cellular metabolic process involving nucleobases, nucleosides, nucleotides and nucleic acids.
6140	regulation of nucleotide metabolic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nucleotides.
6141	regulation of purine nucleobase metabolic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving purines.
6142	regulation of pyrimidine nucleobase metabolic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving pyrimidine nucleobases.
6144	purine nucleobase metabolic process	P	The chemical reactions and pathways involving purine nucleobases, one of the two classes of nitrogen-containing ring compounds found in DNA and RNA, which include adenine and guanine.
6145	purine nucleobase catabolic process	P	The chemical reactions and pathways resulting in the breakdown of purine nucleobases, one of the two classes of nitrogen-containing ring compounds found in DNA and RNA, which include adenine and guanine.
6146	adenine catabolic process	P	The chemical reactions and pathways resulting in the breakdown of adenine, 6-aminopurine, one of the 5 main bases found in nucleic acids and a component of numerous important derivatives of its corresponding ribonucleoside, adenosine.
6147	guanine catabolic process	P	The chemical reactions and pathways resulting in the breakdown of guanine, 2-amino-6-hydroxypurine, a purine that is one of the five main bases found in nucleic acids and a component of a number of phosphorylated guanosine derivatives whose metabolic or regulatory functions are important.
6148	inosine catabolic process	P	The chemical reactions and pathways resulting in the breakdown of inosine, hypoxanthine riboside, a nucleoside found free but not in combination in nucleic acids except in the anticodons of some tRNAs.
6149	deoxyinosine catabolic process	P	The chemical reactions and pathways resulting in the breakdown of deoxyinosine, hypoxanthine deoxyriboside.
6150	hypoxanthine oxidation	P	The chemical reactions and pathways resulting in the breakdown of hypoxanthine to xanthine and thence to uric acid.
6151	xanthine oxidation	P	The oxidation of xanthine, 2,6-dihydroxypurine, a purine formed in the metabolic breakdown of guanine but not present in nucleic acids.
6152	purine nucleoside catabolic process	P	The chemical reactions and pathways resulting in the breakdown of purine nucleoside, one of a family of organic molecules consisting of a purine base covalently bonded to a sugar ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside).
6154	adenosine catabolic process	P	The chemical reactions and pathways resulting in the breakdown of adenosine, adenine riboside, a ribonucleoside found widely distributed in cells of every type as the free nucleoside and in combination in nucleic acids and various nucleoside coenzymes.
6157	deoxyadenosine catabolic process	P	The chemical reactions and pathways resulting in the breakdown of deoxyadenosine, 2-deoxyribosyladenine, one of the four major nucleosides of DNA.
6161	deoxyguanosine catabolic process	P	The chemical reactions and pathways resulting in the breakdown of deoxyguanosine, a nucleoside consisting of the base guanine and the sugar deoxyribose.
6163	purine nucleotide metabolic process	P	The chemical reactions and pathways involving a purine nucleotide, a compound consisting of nucleoside (a purine base linked to a deoxyribose or ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.
6164	purine nucleotide biosynthetic process	P	The chemical reactions and pathways resulting in the formation of a purine nucleotide, a compound consisting of nucleoside (a purine base linked to a deoxyribose or ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.
6165	nucleoside diphosphate phosphorylation	P	The process of introducing a phosphate group into a nucleoside diphosphate to produce a nucleoside triphosphate.
6166	purine ribonucleoside salvage	P	Any process which produces a purine nucleoside from derivatives of it, without de novo synthesis.
6167	AMP biosynthetic process	P	The chemical reactions and pathways resulting in the formation of AMP, adenosine monophosphate.
6168	adenine salvage	P	Any process that generates adenine, 6-aminopurine, from derivatives of it without de novo synthesis.
6169	adenosine salvage	P	Any process that generates adenosine, adenine riboside, from derivatives of it without de novo synthesis.
6170	dAMP biosynthetic process	P	The chemical reactions and pathways resulting in the formation of dAMP, deoxyadenosine monophosphate (2'-deoxyadenosine 5'-phosphate).
6171	cAMP biosynthetic process	P	The chemical reactions and pathways resulting in the formation of the nucleotide cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate).
6172	ADP biosynthetic process	P	The chemical reactions and pathways resulting in the formation of ADP, adenosine 5'-diphosphate.
6173	dADP biosynthetic process	P	The chemical reactions and pathways resulting in the formation of dADP, deoxyadenosine diphosphate (2'-deoxyadenosine 5'-diphosphate).
6174	dADP phosphorylation	P	The process of introducing a phosphate group into dADP, deoxyadenosine diphosphate, to produce dATP.
6175	dATP biosynthetic process	P	The chemical reactions and pathways resulting in the formation of dATP, deoxyadenosine triphosphate (2'-deoxyadenosine 5'-triphosphate).
6176	dATP biosynthetic process from ADP	P	The chemical reactions and pathways resulting in the formation of dATP, deoxyadenosine triphosphate (2'-deoxyadenosine 5'-triphosphate) from other compounds, including ADP, adenosine diphosphate.
6177	GMP biosynthetic process	P	The chemical reactions and pathways resulting in the formation of GMP, guanosine monophosphate.
6178	guanine salvage	P	Any process that generates guanine, 2-amino-6-hydroxypurine, from derivatives of it without de novo synthesis.
6179	guanosine salvage	P	Any process that generates guanosine, guanine riboside, from derivatives of it without de novo synthesis.
6180	deoxyguanosine salvage	P	Any process that generates deoxyguanosine from derivatives of it, without de novo synthesis.
6181	dGMP biosynthetic process	P	The chemical reactions and pathways resulting in the formation of dGMP, deoxyguanosine monophosphate (2'-deoxyguanosine 5'-phosphate).
6182	cGMP biosynthetic process	P	The chemical reactions and pathways resulting in the formation of cyclic GMP, guanosine 3',5'-phosphate.
6183	GTP biosynthetic process	P	The chemical reactions and pathways resulting in the formation of GTP, guanosine triphosphate.
6185	dGDP biosynthetic process	P	The chemical reactions and pathways resulting in the formation of dGDP, deoxyguanosine diphosphate, (2'-deoxyguanosine 5'-diphosphate).
6186	dGDP phosphorylation	P	The process of introducing a phosphate group into dGDP, deoxyguanosine diphosphate, to produce dGTP.
6187	dGTP biosynthetic process from dGDP	P	The chemical reactions and pathways resulting in the formation of dGTP, deoxyguanosine triphosphate (2'-deoxyguanosine 5'-triphosphate) from other compounds, including gGDP, deoxyguanosine diphosphate.
6188	IMP biosynthetic process	P	The chemical reactions and pathways resulting in the formation of IMP, inosine monophosphate.
6189	'de novo' IMP biosynthetic process	P	The chemical reactions and pathways resulting in the formation of IMP, inosine monophosphate, by the stepwise assembly of a purine ring on ribose 5-phosphate.
6190	inosine salvage	P	Any process that generates inosine, hypoxanthine riboside, from derivatives of it without de novo synthesis.
6191	deoxyinosine salvage	P	Any process that generates deoxyinosine from derivatives of it, without de novo synthesis.
6192	IDP phosphorylation	P	The process of introducing a phosphate group into IDP, inosine (5'-)diphosphate, to produce ITP.
6193	ITP catabolic process	P	The chemical reactions and pathways resulting in the breakdown of ITP, inosine (5'-)triphosphate.
6194	dIDP phosphorylation	P	The process of introducing a phosphate group into dIDP, deoxyinosine diphosphate, to produce dITP.
6195	purine nucleotide catabolic process	P	The chemical reactions and pathways resulting in the breakdown of a purine nucleotide, a compound consisting of nucleoside (a purine base linked to a deoxyribose or ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.
6196	AMP catabolic process	P	The chemical reactions and pathways resulting in the breakdown of AMP, adenosine monophosphate.
6198	cAMP catabolic process	P	The chemical reactions and pathways resulting in the breakdown of the nucleotide cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate).
6201	GMP catabolic process to IMP	P	The chemical reactions and pathways resulting in the breakdown of guanosine monophosphate into other compounds, including inosine monophosphate.
6202	GMP catabolic process to guanine	P	The chemical reactions and pathways resulting in the breakdown of guanosine monophosphate into other compounds, including guanine.
6203	dGTP catabolic process	P	The chemical reactions and pathways resulting in the breakdown of dGTP, guanosine triphosphate.
6204	IMP catabolic process	P	The chemical reactions and pathways resulting in the breakdown of IMP, inosine monophosphate.
6206	pyrimidine nucleobase metabolic process	P	The chemical reactions and pathways involving pyrimidine nucleobases, 1,3-diazine, organic nitrogenous bases.
6207	'de novo' pyrimidine nucleobase biosynthetic process	P	The chemical reactions and pathways resulting in the formation of pyrimidine nucleobases, 1,3-diazine, organic nitrogenous bases, beginning with the synthesis of a pyrimidine ring from simpler precursors.
6208	pyrimidine nucleobase catabolic process	P	The chemical reactions and pathways resulting in the breakdown of pyrimidine nucleobases, 1,3-diazine, organic nitrogenous bases.
6209	cytosine catabolic process	P	The chemical reactions and pathways resulting in the breakdown of cytosine, 4-amino-2-hydroxypyrimidine, a pyrimidine derivative that is one of the five main bases found in nucleic acids; it occurs widely in cytidine derivatives.
6210	thymine catabolic process	P	The chemical reactions and pathways resulting in the breakdown of thymine, 5-methyluracil, one of the two major pyrimidine bases present (as thymidine) in DNA but not found in RNA other than (as ribothymidine) in transfer RNA, where it is a minor base.
6211	5-methylcytosine catabolic process	P	The chemical reactions and pathways resulting in the breakdown of 5-methylcytosine, a methylated base of DNA.
6212	uracil catabolic process	P	The chemical reactions and pathways resulting in the breakdown of uracil, 2,4-dioxopyrimidine, one of the pyrimidine bases occurring in RNA, but not in DNA.
6213	pyrimidine nucleoside metabolic process	P	The chemical reactions and pathways involving any pyrimidine nucleoside, one of a family of organic molecules consisting of a pyrimidine base covalently bonded to ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside).
6214	thymidine catabolic process	P	The chemical reactions and pathways resulting in the breakdown of thymidine, deoxyribosylthymine thymine 2-deoxyriboside, a deoxynucleoside very widely distributed but occurring almost entirely as phosphoric esters in deoxynucleotides and deoxyribonucleic acid, DNA.
6216	cytidine catabolic process	P	The chemical reactions and pathways resulting in the breakdown of cytidine, cytosine riboside, a widely distributed nucleoside.
6217	deoxycytidine catabolic process	P	The chemical reactions and pathways resulting in the breakdown of deoxycytidine, 2-deoxyribosylcytosine, one of the four major nucleosides of DNA.
6218	uridine catabolic process	P	The chemical reactions and pathways resulting in the breakdown of uridine, uracil riboside, a ribonucleoside very widely distributed but occurring almost entirely as phosphoric esters in ribonucleotides and ribonucleic acids.
6219	deoxyuridine catabolic process	P	The chemical reactions and pathways resulting in the breakdown of deoxyuridine, 2-deoxyribosyluracil, one of the four major nucleosides of DNA.
6220	pyrimidine nucleotide metabolic process	P	The chemical reactions and pathways involving a pyrimidine nucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a deoxyribose or ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.
6221	pyrimidine nucleotide biosynthetic process	P	The chemical reactions and pathways resulting in the formation of a pyrimidine nucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a deoxyribose or ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.
6222	UMP biosynthetic process	P	The chemical reactions and pathways resulting in the formation of UMP, uridine monophosphate.
6223	uracil salvage	P	Any process that generates uracil, 2,4-dioxopyrimidine, from derivatives of it without de novo synthesis.
6225	UDP biosynthetic process	P	The chemical reactions and pathways resulting in the formation of UDP, uridine (5'-)diphosphate.
6226	dUMP biosynthetic process	P	The chemical reactions and pathways resulting in the formation of dUMP, deoxyuridine monophosphate (2'-deoxyuridine 5'-phosphate).
6227	dUDP biosynthetic process	P	The chemical reactions and pathways resulting in the formation of dUDP, deoxyuridine diphosphate (2'-deoxy-5'-uridylyl phosphate).
6228	UTP biosynthetic process	P	The chemical reactions and pathways resulting in the formation of UTP, uridine (5'-)triphosphate.
6229	dUTP biosynthetic process	P	The chemical reactions and pathways resulting in the formation of dUTP, deoxyuridine (5'-)triphosphate.
6230	TMP biosynthetic process	P	The chemical reactions and pathways resulting in the formation of TMP, ribosylthymine monophosphate.
6231	dTMP biosynthetic process	P	The chemical reactions and pathways resulting in the formation of dTMP, deoxyribosylthymine monophosphate (2'-deoxyribosylthymine 5'-phosphate).
6232	TDP biosynthetic process	P	The chemical reactions and pathways resulting in the formation of TDP, ribosylthymine diphosphate.
6233	dTDP biosynthetic process	P	The chemical reactions and pathways resulting in the formation of dTDP, deoxyribosylthymine diphosphate (2'-deoxyribosylthymine5'-diphosphate).
6234	TTP biosynthetic process	P	The chemical reactions and pathways resulting in the formation of TTP, ribosylthymine triphosphate.
6235	dTTP biosynthetic process	P	The chemical reactions and pathways resulting in the formation of dTTP, deoxyribosylthymine triphosphate.
6236	cytidine salvage	P	Any process that generates cytidine, cytosine riboside, from derivatives of it without de novo synthesis.
6237	deoxycytidine salvage	P	Any process that generates deoxycytidine, 2-deoxyribosylcytosine, from derivatives of it, without de novo synthesis.
6238	CMP salvage	P	Any process that generates CMP, cytidine monophosphate, from derivatives of it without de novo synthesis.
6239	dCMP salvage	P	Any process that generates dCMP, deoxycytidine monophosphate from derivatives of it, without de novo synthesis.
6240	dCDP biosynthetic process	P	The chemical reactions and pathways resulting in the formation of dCDP, deoxycytidine 5'-diphosphate.
6241	CTP biosynthetic process	P	The chemical reactions and pathways resulting in the formation of CTP, cytidine 5'-triphosphate.
6242	dCTP biosynthetic process	P	The chemical reactions and pathways resulting in the formation of dCTP, deoxycytidine triphosphate.
6244	pyrimidine nucleotide catabolic process	P	The chemical reactions and pathways resulting in the breakdown of a pyrimidine nucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a deoxyribose or ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.
6245	TDP catabolic process	P	The chemical reactions and pathways resulting in the breakdown of TDP, ribosylthymine diphosphate.
6246	dTDP catabolic process	P	The chemical reactions and pathways resulting in the breakdown of dTDP, deoxyribosylthymine diphosphate.
6248	CMP catabolic process	P	The chemical reactions and pathways resulting in the breakdown of CMP, cytidine monophosphate.
6249	dCMP catabolic process	P	The chemical reactions and pathways resulting in the breakdown of dCMP, deoxycytidine monophosphate.
6251	dCDP catabolic process	P	The chemical reactions and pathways resulting in the breakdown of dCDP, deoxycytidine 5'-diphosphate.
6253	dCTP catabolic process	P	The chemical reactions and pathways resulting in the breakdown of dCTP, deoxycytidine triphosphate.
6254	CTP catabolic process	P	The chemical reactions and pathways resulting in the breakdown of CTP, cytidine 5'-triphosphate.
6256	UDP catabolic process	P	The chemical reactions and pathways resulting in the breakdown of UDP, uridine (5'-)diphosphate.
6257	dUDP catabolic process	P	The chemical reactions and pathways resulting in the breakdown of dUDP, deoxyuridine (5'-)diphosphate.
6258	UDP-glucose catabolic process	P	The chemical reactions and pathways resulting in the breakdown of UDP-glucose, uridinediphosphoglucose, a substance composed of glucose in glycosidic linkage with uridine diphosphate.
6259	DNA metabolic process	P	Any cellular metabolic process involving deoxyribonucleic acid. This is one of the two main types of nucleic acid, consisting of a long, unbranched macromolecule formed from one, or more commonly, two, strands of linked deoxyribonucleotides.
6260	DNA replication	P	The cellular metabolic process in which a cell duplicates one or more molecules of DNA. DNA replication begins when specific sequences, known as origins of replication, are recognized and bound by initiation proteins, and ends when the original DNA molecule has been completely duplicated and the copies topologically separated. The unit of replication usually corresponds to the genome of the cell, an organelle, or a virus. The template for replication can either be an existing DNA molecule or RNA.
6261	DNA-dependent DNA replication	P	A DNA replication process that uses parental DNA as a template for the DNA-dependent DNA polymerases that synthesize the new strands.
6264	mitochondrial DNA replication	P	The process in which new strands of DNA are synthesized in the mitochondrion.
6265	DNA topological change	P	The process in which a transformation is induced in the topological structure of a double-stranded DNA helix, resulting in a change in linking number.
6266	DNA ligation	P	The re-formation of a broken phosphodiester bond in the DNA backbone, carried out by DNA ligase.
6267	pre-replicative complex assembly involved in nuclear cell cycle DNA replication	P	The aggregation, arrangement and bonding together of a set of components to form the nuclear pre-replicative complex, a protein-DNA complex that forms at the eukaryotic DNA replication origin and is required for replication initiation.
6268	DNA unwinding involved in DNA replication	P	The process in which interchain hydrogen bonds between two strands of DNA are broken or 'melted', generating unpaired template strands for DNA replication.
6269	DNA replication, synthesis of RNA primer	P	The synthesis of a short RNA polymer, usually 4-15 nucleotides long, using one strand of unwound DNA as a template; the RNA then serves as a primer from which DNA polymerases extend synthesis.
6270	DNA replication initiation	P	The process in which DNA-dependent DNA replication is started; this involves the separation of a stretch of the DNA double helix, the recruitment of DNA polymerases and the initiation of polymerase action.
6271	DNA strand elongation involved in DNA replication	P	The process in which a DNA strand is synthesized from template DNA during replication by the action of polymerases, which add nucleotides to the 3' end of the nascent DNA strand.
6272	leading strand elongation	P	The synthesis of DNA from a template strand in the 5' to 3' direction; leading strand elongation is continuous as it proceeds in the same direction as the replication fork.
6273	lagging strand elongation	P	The synthesis of DNA from a template strand in a net 3' to 5' direction. Lagging strand DNA elongation proceeds by discontinuous synthesis of short stretches of DNA, known as Okazaki fragments, from RNA primers; these fragments are then joined by DNA ligase. Although each segment of nascent DNA is synthesized in the 5' to 3' direction, the overall direction of lagging strand synthesis is 3' to 5', mirroring the progress of the replication fork.
6274	DNA replication termination	P	The process in which DNA replication at a replication fork ceases; occurs when the replication fork reaches a specific termination site or when two replication forks meet.
6275	regulation of DNA replication	P	Any process that modulates the frequency, rate or extent of DNA replication.
6276	plasmid maintenance	P	The maintenance of the integrity of extrachromosomal plasmid DNA; includes processes that ensure plasmids are retained in the daughter cells after cell division.
6277	DNA amplification	P	The process in which the number of copies of a gene is increased in certain cells as extra copies of DNA are made in response to certain signals of cell development or of stress from the environment.
6278	RNA-dependent DNA biosynthetic process	P	A DNA biosynthetic process that uses RNA as a template for RNA-dependent DNA polymerases (e.g. reverse transcriptase) that synthesize the new strand.
6279	premeiotic DNA replication	P	The replication of DNA that precedes meiotic cell division.
6281	DNA repair	P	The process of restoring DNA after damage. Genomes are subject to damage by chemical and physical agents in the environment (e.g. UV and ionizing radiations, chemical mutagens, fungal and bacterial toxins, etc.) and by free radicals or alkylating agents endogenously generated in metabolism. DNA is also damaged because of errors during its replication. A variety of different DNA repair pathways have been reported that include direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway.
6282	regulation of DNA repair	P	Any process that modulates the frequency, rate or extent of DNA repair.
6283	transcription-coupled nucleotide-excision repair	P	The nucleotide-excision repair process that carries out preferential repair of DNA lesions on the actively transcribed strand of the DNA duplex. In addition, the transcription-coupled nucleotide-excision repair pathway is required for the recognition and repair of a small subset of lesions that are not recognized by the global genome nucleotide excision repair pathway.
6284	base-excision repair	P	In base excision repair, an altered base is removed by a DNA glycosylase enzyme, followed by excision of the resulting sugar phosphate. The small gap left in the DNA helix is filled in by the sequential action of DNA polymerase and DNA ligase.
6285	base-excision repair, AP site formation	P	The formation of an AP site, a deoxyribose sugar with a missing base, by DNA glycosylase which recognizes an altered base in DNA and catalyzes its hydrolytic removal. This sugar phosphate is the substrate recognized by the AP endonuclease, which cuts the DNA phosphodiester backbone at the 5' side of the altered site to leave a gap which is subsequently repaired.
6286	base-excision repair, base-free sugar-phosphate removal	P	Excision of the sugar phosphate residue at an AP site, i.e. a deoxyribose sugar with a missing base, by a phosphodiesterase enzyme.
6287	base-excision repair, gap-filling	P	Repair of the damaged strand by the combined action of an apurinic endouclease that degrades a few bases on the damaged strand and a polymerase that synthesizes a 'patch' in the 5' to 3' direction, using the undamaged strand as a template.
6288	base-excision repair, DNA ligation	P	The ligation by DNA ligase of DNA strands. Ligation occurs after polymerase action to fill the gap left by the action of endonucleases during base-excision repair.
6289	nucleotide-excision repair	P	A DNA repair process in which a small region of the strand surrounding the damage is removed from the DNA helix as an oligonucleotide. The small gap left in the DNA helix is filled in by the sequential action of DNA polymerase and DNA ligase. Nucleotide excision repair recognizes a wide range of substrates, including damage caused by UV irradiation (pyrimidine dimers and 6-4 photoproducts) and chemicals (intrastrand cross-links and bulky adducts).
6290	pyrimidine dimer repair	P	The repair of UV-induced T-T, C-T and C-C dimers.
6293	nucleotide-excision repair, preincision complex stabilization	P	The stabilization of the multiprotein complex involved in damage recognition, DNA helix unwinding, and endonucleolytic cleavage at the site of DNA damage as well as the unwound DNA. The stabilization of the protein-DNA complex ensures proper positioning of the preincision complex before the phosphodiester backbone of the damaged strand is cleaved 3' and 5' of the site of DNA damage.
6294	nucleotide-excision repair, preincision complex assembly	P	The aggregation, arrangement and bonding together of proteins on DNA to form the multiprotein complex involved in damage recognition, DNA helix unwinding, and endonucleolytic cleavage at the site of DNA damage. This assembly occurs before the phosphodiester backbone of the damaged strand is cleaved 3' and 5' of the site of DNA damage.
6295	nucleotide-excision repair, DNA incision, 3'-to lesion	P	The endonucleolytic cleavage of the damaged strand of DNA 3' to the site of damage. The incision occurs at the junction of single-stranded DNA and double-stranded DNA that is formed when the DNA duplex is unwound. The incision precedes the incision formed 5' to the site of damage.
6296	nucleotide-excision repair, DNA incision, 5'-to lesion	P	The endonucleolytic cleavage of the damaged strand of DNA 5' to the site of damage. The incision occurs at the junction of single-stranded DNA and double-stranded DNA that is formed when the DNA duplex is unwound. The incision follows the incision formed 3' to the site of damage.
6297	nucleotide-excision repair, DNA gap filling	P	Repair of the gap in the DNA helix by DNA polymerase and DNA ligase after the portion of the strand containing the lesion has been removed by pyrimidine-dimer repair enzymes.
6298	mismatch repair	P	A system for the correction of errors in which an incorrect base, which cannot form hydrogen bonds with the corresponding base in the parent strand, is incorporated into the daughter strand. The mismatch repair system promotes genomic fidelity by repairing base-base mismatches, insertion-deletion loops and heterologies generated during DNA replication and recombination.
6301	postreplication repair	P	The conversion of DNA-damage induced single-stranded gaps into large molecular weight DNA after replication. Includes pathways that remove replication-blocking lesions in conjunction with DNA replication.
6302	double-strand break repair	P	The repair of double-strand breaks in DNA via homologous and nonhomologous mechanisms to reform a continuous DNA helix.
6303	double-strand break repair via nonhomologous end joining	P	The repair of a double-strand break in DNA in which the two broken ends are rejoined with little or no sequence complementarity. Information at the DNA ends may be lost due to the modification of broken DNA ends. This term covers instances of separate pathways, called classical (or canonical) and alternative nonhomologous end joining (C-NHEJ and A-NHEJ). These in turn may further branch into sub-pathways, but evidence is still unclear.
6304	DNA modification	P	The covalent alteration of one or more nucleotide sites in DNA, resulting in a change in its properties.
6305	DNA alkylation	P	The addition of alkyl groups to many positions on all four bases of DNA. Alkylating agents can also modify the bases of incoming nucleotides in the course of DNA synthesis.
6306	DNA methylation	P	The covalent transfer of a methyl group to either N-6 of adenine or C-5 or N-4 of cytosine.
6307	DNA dealkylation involved in DNA repair	P	The repair of alkylation damage, e.g. the removal of the alkyl group at the O6-position of guanine by O6-alkylguanine-DNA alkyltransferase (AGT).
6308	DNA catabolic process	P	The cellular DNA metabolic process resulting in the breakdown of DNA, deoxyribonucleic acid, one of the two main types of nucleic acid, consisting of a long unbranched macromolecule formed from one or two strands of linked deoxyribonucleotides, the 3'-phosphate group of each constituent deoxyribonucleotide being joined in 3',5'-phosphodiester linkage to the 5'-hydroxyl group of the deoxyribose moiety of the next one.
6309	apoptotic DNA fragmentation	P	The cleavage of DNA during apoptosis, which usually occurs in two stages: cleavage into fragments of about 50 kbp followed by cleavage between nucleosomes to yield 200 bp fragments.
6310	DNA recombination	P	Any process in which a new genotype is formed by reassortment of genes resulting in gene combinations different from those that were present in the parents. In eukaryotes genetic recombination can occur by chromosome assortment, intrachromosomal recombination, or nonreciprocal interchromosomal recombination. Intrachromosomal recombination occurs by crossing over. In bacteria it may occur by genetic transformation, conjugation, transduction, or F-duction.
6311	meiotic gene conversion	P	The cell cycle process in which genetic information is transferred from one helix to another. It often occurs in association with general genetic recombination events, and is believed to be a straightforward consequence of the mechanisms of general recombination and DNA repair. For example, meiosis might yield three copies of the maternal version of an allele and only one copy of the paternal allele, indicating that one of the two copies of the paternal allele has been changed to a copy of the maternal allele.
6312	mitotic recombination	P	The exchange, reciprocal or nonreciprocal, of genetic material between one DNA molecule and a homologous region of DNA that occurs during mitotic cell cycles.
6313	transposition, DNA-mediated	P	Any process involved in a type of transpositional recombination which occurs via a DNA intermediate.
6314	intron homing	P	Lateral transfer of an intron to a homologous allele that lacks the intron, mediated by a site-specific endonuclease encoded within the mobile intron.
6315	homing of group II introns	P	Lateral transfer of a group II intron to a homologous allele that lacks the intron, mediated by a site-specific endonuclease encoded within the mobile intron; group II introns are self-splicing introns with a conserved secondary structure.
6316	movement of group I intron	P	Lateral transfer of a group I intron to a homologous allele that lacks the intron, mediated by a site-specific endonuclease encoded within the mobile intron; group I introns are self-splicing introns that use guanosine as a cofactor in the splicing reaction.
6323	DNA packaging	P	Any process in which DNA and associated proteins are formed into a compact, orderly structure.
6325	chromatin organization	P	Any process that results in the specification, formation or maintenance of the physical structure of eukaryotic chromatin.
6333	chromatin assembly or disassembly	P	The formation or destruction of chromatin structures.
6334	nucleosome assembly	P	The aggregation, arrangement and bonding together of a nucleosome, the beadlike structural units of eukaryotic chromatin composed of histones and DNA.
6335	DNA replication-dependent nucleosome assembly	P	The formation of nucleosomes on newly replicated DNA, coupled to strand elongation.
6336	DNA replication-independent nucleosome assembly	P	The formation of nucleosomes outside the context of DNA replication.
6337	nucleosome disassembly	P	The controlled breakdown of nucleosomes, the beadlike structural units of eukaryotic chromatin composed of histones and DNA.
6338	chromatin remodeling	P	Dynamic structural changes to eukaryotic chromatin occurring throughout the cell division cycle. These changes range from the local changes necessary for transcriptional regulation to global changes necessary for chromosome segregation.
6342	chromatin silencing	P	Repression of transcription by altering the structure of chromatin, e.g. by conversion of large regions of DNA into an inaccessible state often called heterochromatin.
6343	establishment of chromatin silencing	P	The initial formation of a transcriptionally silent chromatin structure such as heterochromatin.
6344	maintenance of chromatin silencing	P	The maintenance of chromatin in a transcriptionally silent state such as heterochromatin.
6346	methylation-dependent chromatin silencing	P	Repression of transcription by methylation of DNA, leading to the formation of heterochromatin.
6348	chromatin silencing at telomere	P	Repression of transcription of telomeric DNA by altering the structure of chromatin.
6349	regulation of gene expression by genetic imprinting	P	Heritable alterations in the activity of a gene that depend on whether it passed through the paternal or the maternal germline, but that are not encoded by DNA itself.
6351	transcription, DNA-templated	P	The cellular synthesis of RNA on a template of DNA.
6352	DNA-templated transcription, initiation	P	Any process involved in the assembly of the RNA polymerase preinitiation complex (PIC) at the core promoter region of a DNA template, resulting in the subsequent synthesis of RNA from that promoter. The initiation phase includes PIC assembly and the formation of the first few bonds in the RNA chain, including abortive initiation, which occurs when the first few nucleotides are repeatedly synthesized and then released. The initiation phase ends just before and does not include promoter clearance, or release, which is the transition between the initiation and elongation phases of transcription.
6353	DNA-templated transcription, termination	P	The cellular process that completes DNA-templated transcription; the formation of phosphodiester bonds ceases, the RNA-DNA hybrid dissociates, and RNA polymerase releases the DNA.
6354	DNA-templated transcription, elongation	P	The extension of an RNA molecule after transcription initiation and promoter clearance at a DNA-dependent RNA polymerase promoter by the addition of ribonucleotides catalyzed by an RNA polymerase.
6355	regulation of transcription, DNA-templated	P	Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
6356	regulation of transcription from RNA polymerase I promoter	P	Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase I promoter.
6357	regulation of transcription from RNA polymerase II promoter	P	Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter.
6359	regulation of transcription from RNA polymerase III promoter	P	Any process that modulates the frequency, rate or extent of transcription from an RNA ploymerase III promoter.
6360	transcription from RNA polymerase I promoter	P	The synthesis of RNA from a DNA template by RNA polymerase I (RNAP I), originating at an RNAP I promoter.
6361	transcription initiation from RNA polymerase I promoter	P	Any process involved in the assembly of the RNA polymerase I preinitiation complex (PIC) at an RNA polymerase I promoter region of a DNA template, resulting in the subsequent synthesis of RNA from that promoter. The initiation phase includes PIC assembly and the formation of the first few bonds in the RNA chain, including abortive initiation, which occurs when the first few nucleotides are repeatedly synthesized and then released. Promoter clearance, or release, is the transition between the initiation and elongation phases of transcription.
6362	transcription elongation from RNA polymerase I promoter	P	The extension of an RNA molecule after transcription initiation and promoter clearance at an RNA polymerase I specific promoter by the addition of ribonucleotides catalyzed by RNA polymerase I.
6363	termination of RNA polymerase I transcription	P	The process in which the synthesis of an RNA molecule by RNA polymerase I using a DNA template is completed. RNAP I termination requires binding of a terminator protein so specific sequences downstream of the transcription unit.
6364	rRNA processing	P	Any process involved in the conversion of a primary ribosomal RNA (rRNA) transcript into one or more mature rRNA molecules.
6366	transcription from RNA polymerase II promoter	P	The synthesis of RNA from a DNA template by RNA polymerase II, originating at an RNA polymerase II promoter. Includes transcription of messenger RNA (mRNA) and certain small nuclear RNAs (snRNAs).
6367	transcription initiation from RNA polymerase II promoter	P	Any process involved in the assembly of the RNA polymerase II preinitiation complex (PIC) at an RNA polymerase II promoter region of a DNA template, resulting in the subsequent synthesis of RNA from that promoter. The initiation phase includes PIC assembly and the formation of the first few bonds in the RNA chain, including abortive initiation, which occurs when the first few nucleotides are repeatedly synthesized and then released. Promoter clearance, or release, is the transition between the initiation and elongation phases of transcription.
6368	transcription elongation from RNA polymerase II promoter	P	The extension of an RNA molecule after transcription initiation and promoter clearance at an RNA polymerase II promoter by the addition of ribonucleotides catalyzed by RNA polymerase II.
6369	termination of RNA polymerase II transcription	P	The process in which the synthesis of an RNA molecule by RNA polymerase II using a DNA template is completed.
6370	7-methylguanosine mRNA capping	P	Addition of the 7-methylguanosine cap to the 5' end of a nascent messenger RNA transcript.
6376	mRNA splice site selection	P	Selection of a splice site by components of the assembling spliceosome.
6378	mRNA polyadenylation	P	The enzymatic addition of a sequence of 40-200 adenylyl residues at the 3' end of a eukaryotic mRNA primary transcript.
6379	mRNA cleavage	P	Any process in which a pre-mRNA or mRNA molecule is cleaved at specific sites or in a regulated manner.
6382	adenosine to inosine editing	P	The conversion of an adenosine residue to inosine in an RNA molecule by deamination.
6383	transcription from RNA polymerase III promoter	P	The synthesis of RNA from a DNA template by RNA polymerase III, originating at an RNAP III promoter.
6384	transcription initiation from RNA polymerase III promoter	P	Any process involved in the assembly of the RNA polymerase III preinitiation complex (PIC) at an RNA polymerase III promoter region of a DNA template, resulting in the subsequent synthesis of RNA from that promoter. The initiation phase includes PIC assembly and the formation of the first few bonds in the RNA chain, including abortive initiation, which occurs when the first few nucleotides are repeatedly synthesized and then released. Promoter clearance, or release, is the transition between the initiation and elongation phases of transcription.
6385	transcription elongation from RNA polymerase III promoter	P	The extension of an RNA molecule after transcription initiation and promoter clearance at an RNA polymerase III promoter by the addition of ribonucleotides catalyzed by RNA polymerase III.
6386	termination of RNA polymerase III transcription	P	The process in which transcription by RNA polymerase III is terminated; Pol III has an intrinsic ability to terminate transcription upon incorporation of 4 to 6 contiguous U residues.
6388	tRNA splicing, via endonucleolytic cleavage and ligation	P	Splicing of tRNA substrates via recognition of the folded RNA structure that brings the 5' and 3' splice sites into proximity and cleavage of the RNA at both the 3' and 5' splice sites by an endonucleolytic mechanism, followed by ligation of the exons.
6390	transcription from mitochondrial promoter	P	The synthesis of RNA from a mitochondrial DNA template, usually by a specific mitochondrial RNA polymerase.
6391	transcription initiation from mitochondrial promoter	P	A transcription initiation process that takes place at a promoter on the mitochondrial chromosome, and results in RNA synthesis by a mitochondrial RNA polymerase.
6392	transcription elongation from mitochondrial promoter	P	The extension of an RNA molecule after transcription initiation and promoter clearance at mitochondrial promoter by the addition of ribonucleotides catalyzed by a mitchondrial RNA polymerase.
6393	termination of mitochondrial transcription	P	The process in which the synthesis of an RNA molecule using a mitochondrial DNA template is completed.
6396	RNA processing	P	Any process involved in the conversion of one or more primary RNA transcripts into one or more mature RNA molecules.
6397	mRNA processing	P	Any process involved in the conversion of a primary mRNA transcript into one or more mature mRNA(s) prior to translation into polypeptide.
6398	mRNA 3'-end processing by stem-loop binding and cleavage	P	Any mRNA 3'-end processing that involves the binding to and cleavage of a stem-loop structure. For example, histone mRNAs contain a highly conserved stem-loop sequence at the 3' end of the mRNA with a 6 base pairs (bp) stem and a 4-nt loop. The mRNA is cleaved between these two elements, after the fourth or fifth nucleotide, which is typically an adenosine.
6399	tRNA metabolic process	P	The chemical reactions and pathways involving tRNA, transfer RNA, a class of relatively small RNA molecules responsible for mediating the insertion of amino acids into the sequence of nascent polypeptide chains during protein synthesis. Transfer RNA is characterized by the presence of many unusual minor bases, the function of which has not been completely established.
6400	tRNA modification	P	The covalent alteration of one or more nucleotides within a tRNA molecule to produce a tRNA molecule with a sequence that differs from that coded genetically.
6401	RNA catabolic process	P	The chemical reactions and pathways resulting in the breakdown of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage.
6402	mRNA catabolic process	P	The chemical reactions and pathways resulting in the breakdown of mRNA, messenger RNA, which is responsible for carrying the coded genetic 'message', transcribed from DNA, to sites of protein assembly at the ribosomes.
6403	RNA localization	P	A process in which RNA is transported to, or maintained in, a specific location.
6404	RNA import into nucleus	P	The import of RNA from the cytoplasm to the nucleus.
6405	RNA export from nucleus	P	The directed movement of RNA from the nucleus to the cytoplasm.
6406	mRNA export from nucleus	P	The directed movement of mRNA from the nucleus to the cytoplasm.
6407	rRNA export from nucleus	P	The directed movement of rRNA from the nucleus to the cytoplasm; the rRNA is usually in the form of ribonucleoproteins.
6408	snRNA export from nucleus	P	The directed movement of snRNA from the nucleus to the cytoplasm.
6409	tRNA export from nucleus	P	The directed movement of tRNA from the nucleus to the cytoplasm.
6412	translation	P	The cellular metabolic process in which a protein is formed, using the sequence of a mature mRNA molecule to specify the sequence of amino acids in a polypeptide chain. Translation is mediated by the ribosome, and begins with the formation of a ternary complex between aminoacylated initiator methionine tRNA, GTP, and initiation factor 2, which subsequently associates with the small subunit of the ribosome and an mRNA. Translation ends with the release of a polypeptide chain from the ribosome.
6413	translational initiation	P	The process preceding formation of the peptide bond between the first two amino acids of a protein. This includes the formation of a complex of the ribosome, mRNA, and an initiation complex that contains the first aminoacyl-tRNA.
6414	translational elongation	P	The successive addition of amino acid residues to a nascent polypeptide chain during protein biosynthesis.
6415	translational termination	P	The process resulting in the release of a polypeptide chain from the ribosome, usually in response to a termination codon (UAA, UAG, or UGA in the universal genetic code).
6417	regulation of translation	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA.
6418	tRNA aminoacylation for protein translation	P	The synthesis of aminoacyl tRNA by the formation of an ester bond between the 3'-hydroxyl group of the most 3' adenosine of the tRNA, to be used in ribosome-mediated polypeptide synthesis.
6419	alanyl-tRNA aminoacylation	P	The process of coupling alanine to alanyl-tRNA, catalyzed by alanyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.
6420	arginyl-tRNA aminoacylation	P	The process of coupling arginine to arginyl-tRNA, catalyzed by arginyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.
6421	asparaginyl-tRNA aminoacylation	P	The process of coupling asparagine to asparaginyl-tRNA, catalyzed by asparaginyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.
6422	aspartyl-tRNA aminoacylation	P	The process of coupling aspartate to aspartyl-tRNA, catalyzed by aspartyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.
6423	cysteinyl-tRNA aminoacylation	P	The process of coupling cysteine to cysteinyl-tRNA, catalyzed by cysteinyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.
6424	glutamyl-tRNA aminoacylation	P	The process of coupling glutamate to glutamyl-tRNA, catalyzed by glutamyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'- adenosine residue of the tRNA.
6425	glutaminyl-tRNA aminoacylation	P	The process of coupling glutamine to glutaminyl-tRNA, catalyzed by glutaminyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'- adenosine residue of the tRNA.
6426	glycyl-tRNA aminoacylation	P	The process of coupling glycine to glycyl-tRNA, catalyzed by glycyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.
6427	histidyl-tRNA aminoacylation	P	The process of coupling histidine to histidyl-tRNA, catalyzed by histidyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.
6428	isoleucyl-tRNA aminoacylation	P	The process of coupling isoleucine to isoleucyl-tRNA, catalyzed by isoleucyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.
6429	leucyl-tRNA aminoacylation	P	The process of coupling leucine to leucyl-tRNA, catalyzed by leucyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.
6430	lysyl-tRNA aminoacylation	P	The process of coupling lysine to lysyl-tRNA, catalyzed by lysyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.
6431	methionyl-tRNA aminoacylation	P	The process of coupling methionine to methionyl-tRNA, catalyzed by methionyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.
6432	phenylalanyl-tRNA aminoacylation	P	The process of coupling phenylalanine to phenylalanyl-tRNA, catalyzed by phenylalanyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.
6433	prolyl-tRNA aminoacylation	P	The process of coupling proline to prolyl-tRNA, catalyzed by prolyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.
6434	seryl-tRNA aminoacylation	P	The process of coupling serine to seryl-tRNA, catalyzed by seryl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.
6435	threonyl-tRNA aminoacylation	P	The process of coupling threonine to threonyl-tRNA, catalyzed by threonyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.
6436	tryptophanyl-tRNA aminoacylation	P	The process of coupling tryptophan to tryptophanyl-tRNA, catalyzed by tryptophanyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.
6437	tyrosyl-tRNA aminoacylation	P	The process of coupling tyrosine to tyrosyl-tRNA, catalyzed by tyrosyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.
6438	valyl-tRNA aminoacylation	P	The process of coupling valine to valyl-tRNA, catalyzed by valyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.
6446	regulation of translational initiation	P	Any process that modulates the frequency, rate or extent of translational initiation.
6447	regulation of translational initiation by iron	P	Any process that modulates the frequency, rate or extent of the translation of certain mRNAs involved in iron metabolism; regulated by the concentration of iron.
6448	regulation of translational elongation	P	Any process that modulates the frequency, rate, extent or accuracy of translational elongation.
6449	regulation of translational termination	P	Any process that modulates the frequency, rate or extent of translational termination.
6450	regulation of translational fidelity	P	Any process that modulates the ability of the translational apparatus to interpret the genetic code.
6451	translational readthrough	P	The continuation of translation beyond a stop codon by the use of a special tRNA that recognizes the UAG and UGA codons as modified amino acids, rather than as termination codons.
6452	translational frameshifting	P	A mechanism whereby different proteins may result from a single mRNA molecule, due to a change in the parsing of three nucleotides per codon relative to an initiating AUG codon.
6457	protein folding	P	The process of assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure.
6458	'de novo' protein folding	P	The process of assisting in the folding of a nascent peptide chain into its correct tertiary structure.
6461	protein complex assembly	P	The aggregation, arrangement and bonding together of a set of components to form a protein complex.
6463	steroid hormone receptor complex assembly	P	The aggregation, arrangement and bonding together of a set of components to form a steroid hormone receptor complex, an intracellular receptor that binds steroid hormones. The complex is often a dimer, and forms after the steroid has bound the receptor.
6464	cellular protein modification process	P	The covalent alteration of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co-translational, post-translational modifications) occurring at the level of an individual cell. Includes the modification of charged tRNAs that are destined to occur in a protein (pre-translation modification).
6465	signal peptide processing	P	The proteolytic removal of a signal peptide from a protein during or after transport to a specific location in the cell.
6468	protein phosphorylation	P	The process of introducing a phosphate group on to a protein.
6469	negative regulation of protein kinase activity	P	Any process that stops, prevents, or reduces the frequency, rate or extent of protein kinase activity.
6470	protein dephosphorylation	P	The process of removing one or more phosphoric residues from a protein.
6471	protein ADP-ribosylation	P	The transfer, from NAD, of ADP-ribose to protein amino acids.
6473	protein acetylation	P	The addition of an acetyl group to a protein amino acid. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid.
6474	N-terminal protein amino acid acetylation	P	The acetylation of the N-terminal amino acid of proteins.
6475	internal protein amino acid acetylation	P	The addition of an acetyl group to a non-terminal amino acid in a protein.
6476	protein deacetylation	P	The removal of an acetyl group from a protein amino acid. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid.
6477	protein sulfation	P	The addition of a sulfate group as an ester to a protein amino acid.
6478	peptidyl-tyrosine sulfation	P	The sulfation of peptidyl-tyrosine residues to form peptidyl-O4'-sulfo-L-tyrosine.
6479	protein methylation	P	The addition of a methyl group to a protein amino acid. A methyl group is derived from methane by the removal of a hydrogen atom.
6480	N-terminal protein amino acid methylation	P	The methylation of the N-terminal amino acid of a protein.
6481	C-terminal protein methylation	P	The methylation of the C-terminal amino acid of a protein.
6482	protein demethylation	P	The removal of a methyl group, from a protein amino acid. A methyl group is derived from methane by the removal of a hydrogen atom.
6486	protein glycosylation	P	A protein modification process that results in the addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid, e.g. the addition of glycan chains to proteins.
6487	protein N-linked glycosylation	P	A protein glycosylation process in which a carbohydrate or carbohydrate derivative unit is added to a protein via the N4 atom of peptidyl-asparagine, the omega-N of arginine, or the N1' atom peptidyl-tryptophan.
6488	dolichol-linked oligosaccharide biosynthetic process	P	The chemical reactions and pathways resulting in the formation of dolichol-linked oligosaccharide, usually by a stepwise addition of glycosyl chains to endoplasmic reticulum membrane-bound dolichol-P.
6489	dolichyl diphosphate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of dolichyl diphosphate, a diphosphorylated dolichol derivative.
6490	oligosaccharide-lipid intermediate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of an oligosaccharide-lipid intermediate, such as a molecule of dolichol-P-man or dolicol-P-Glc used in N-linked glycosylation.
6491	N-glycan processing	P	The conversion of N-linked glycan (N = nitrogen) structures from the initially transferred oligosaccharide to a mature form, by the actions of glycosidases and glycosyltransferases. The early processing steps are conserved and play roles in glycoprotein folding and trafficking.
6493	protein O-linked glycosylation	P	A protein glycosylation process in which a carbohydrate or carbohydrate derivative unit is added to a protein via the hydroxyl group of peptidyl-serine, peptidyl-threonine, peptidyl-hydroxylysine, or peptidyl-hydroxyproline, or via the phenol group of peptidyl-tyrosine, forming an O-glycan.
6497	protein lipidation	P	The covalent attachment of lipid groups to an amino acid in a protein.
6498	N-terminal protein lipidation	P	The covalent attachment of a lipid group to the amino terminus of a protein.
6499	N-terminal protein myristoylation	P	The covalent attachment of a myristoyl group to the N-terminal amino acid residue of a protein.
6500	N-terminal protein palmitoylation	P	The covalent attachment of a palmitoyl group to the N-terminal amino acid residue of a protein.
6501	C-terminal protein lipidation	P	The covalent attachment of a lipid group to the carboxy terminus of a protein.
6505	GPI anchor metabolic process	P	The chemical reactions and pathways involving glycosylphosphatidylinositol anchors, molecular mechanisms for attaching membrane proteins to the lipid bilayer of cell membranes. Structurally they consist of a molecule of phosphatidylinositol to which is linked, via the C-6 hydroxyl of the inositol, a carbohydrate chain. This chain is in turn linked to the protein through an ethanolamine phosphate group, the amino group of which is in amide linkage with the C-terminal carboxyl of the protein chain, the phosphate group being esterified to the C-6 hydroxyl of the terminal mannose of the core carbohydrate chain.
6506	GPI anchor biosynthetic process	P	The chemical reactions and pathways resulting in the formation of a glycosylphosphatidylinositol (GPI) anchor that attaches some membrane proteins to the lipid bilayer of the cell membrane. The phosphatidylinositol group is linked via the C-6 hydroxyl residue of inositol to a carbohydrate chain which is itself linked to the protein via an ethanolamine phosphate group, its amino group forming an amide linkage with the C-terminal carboxyl of the protein. Some GPI anchors have variants on this canonical linkage.
6507	GPI anchor release	P	The GPI anchor metabolic process that results in enzymatic cleavage of the anchor, releasing an anchored protein from the membrane.
6508	proteolysis	P	The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds.
6509	membrane protein ectodomain proteolysis	P	The proteolytic cleavage of transmembrane proteins and release of their ectodomain (extracellular domain).
6511	ubiquitin-dependent protein catabolic process	P	The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of a ubiquitin group, or multiple ubiquitin groups, to the protein.
6513	protein monoubiquitination	P	Addition of a single ubiquitin group to a protein.
6515	misfolded or incompletely synthesized protein catabolic process	P	The chemical reactions and pathways resulting in the breakdown of misfolded or attenuated proteins.
6516	glycoprotein catabolic process	P	The chemical reactions and pathways resulting in the breakdown of glycoproteins, any protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide.
6517	protein deglycosylation	P	The removal of sugar residues from a glycosylated protein.
6518	peptide metabolic process	P	The chemical reactions and pathways involving peptides, compounds of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another.
6520	cellular amino acid metabolic process	P	The chemical reactions and pathways involving amino acids, carboxylic acids containing one or more amino groups, as carried out by individual cells.
6521	regulation of cellular amino acid metabolic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving amino acids.
6522	alanine metabolic process	P	The chemical reactions and pathways involving alanine, 2-aminopropanoic acid.
6523	alanine biosynthetic process	P	The chemical reactions and pathways resulting in the formation of alanine, 2-aminopropanoic acid.
6524	alanine catabolic process	P	The chemical reactions and pathways resulting in the breakdown of alanine, 2-aminopropanoic acid.
6525	arginine metabolic process	P	The chemical reactions and pathways involving arginine, 2-amino-5-(carbamimidamido)pentanoic acid.
6526	arginine biosynthetic process	P	The chemical reactions and pathways resulting in the formation of arginine, 2-amino-5-(carbamimidamido)pentanoic acid.
6527	arginine catabolic process	P	The chemical reactions and pathways resulting in the breakdown of arginine, 2-amino-5-(carbamimidamido)pentanoic acid.
6528	asparagine metabolic process	P	The chemical reactions and pathways involving asparagine, 2-amino-3-carbamoylpropanoic acid.
6529	asparagine biosynthetic process	P	The chemical reactions and pathways resulting in the formation of asparagine, 2-amino-3-carbamoylpropanoic acid.
6530	asparagine catabolic process	P	The chemical reactions and pathways resulting in the breakdown of asparagine, 2-amino-3-carbamoylpropanoic acid.
6531	aspartate metabolic process	P	The chemical reactions and pathways involving aspartate, the anion derived from aspartic acid, 2-aminobutanedioic acid.
6532	aspartate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of aspartate, the anion derived from aspartic acid, 2-aminobutanedioic acid.
6533	aspartate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of aspartate, the anion derived from aspartic acid, 2-aminobutanedioic acid.
6534	cysteine metabolic process	P	The chemical reactions and pathways involving cysteine, 2-amino-3-mercaptopropanoic acid.
6535	cysteine biosynthetic process from serine	P	The chemical reactions and pathways resulting in the formation of cysteine from other compounds, including serine.
6536	glutamate metabolic process	P	The chemical reactions and pathways involving glutamate, the anion of 2-aminopentanedioic acid.
6537	glutamate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of glutamate, the anion of 2-aminopentanedioic acid.
6538	glutamate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of glutamate, the anion of 2-aminopentanedioic acid.
6539	glutamate catabolic process via 2-oxoglutarate	P	The chemical reactions and pathways resulting in the breakdown of glutamate, via the intermediate 2-oxoglutarate.
6540	glutamate decarboxylation to succinate	P	The chemical reactions and pathways resulting in the formation of succinate from glutamate. Also known as GABA (gamma-aminobutyrate) shunt since it channels glutamate into the TCA cycle bypassing two steps of that cycle. There are three enzymes involved in the GABA shunt: glutamate decarboxylase (GAD), GABA aminotransferase (GABA-TA), and succinate semialdehyde dehydrogenase (SSADH). These three enzymes acting in concert to convert glutamate into succinate. The GABA shunt is predominantly associated with neurotransmission in the mammalian brain. It is also present in nonneuronal cells, in plants, in unicellular eukaryotes, and in prokaryotes.
6541	glutamine metabolic process	P	The chemical reactions and pathways involving glutamine, 2-amino-4-carbamoylbutanoic acid.
6542	glutamine biosynthetic process	P	The chemical reactions and pathways resulting in the formation of glutamine, 2-amino-4-carbamoylbutanoic acid.
6543	glutamine catabolic process	P	The chemical reactions and pathways resulting in the breakdown of glutamine, 2-amino-4-carbamoylbutanoic acid.
6544	glycine metabolic process	P	The chemical reactions and pathways involving glycine, aminoethanoic acid.
6545	glycine biosynthetic process	P	The chemical reactions and pathways resulting in the formation of glycine, aminoethanoic acid.
6546	glycine catabolic process	P	The chemical reactions and pathways resulting in the breakdown of glycine, aminoethanoic acid.
6547	histidine metabolic process	P	The chemical reactions and pathways involving histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid.
6548	histidine catabolic process	P	The chemical reactions and pathways resulting in the breakdown of histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid.
6549	isoleucine metabolic process	P	The chemical reactions and pathways involving isoleucine, (2R*,3R*)-2-amino-3-methylpentanoic acid.
6550	isoleucine catabolic process	P	The chemical reactions and pathways resulting in the breakdown of isoleucine, (2R*,3R*)-2-amino-3-methylpentanoic acid.
6551	leucine metabolic process	P	The chemical reactions and pathways involving leucine, 2-amino-4-methylpentanoic acid.
6552	leucine catabolic process	P	The chemical reactions and pathways resulting in the breakdown of leucine, 2-amino-4-methylpentanoic acid.
6553	lysine metabolic process	P	The chemical reactions and pathways involving lysine, 2,6-diaminohexanoic acid.
6554	lysine catabolic process	P	The chemical reactions and pathways resulting in the breakdown of lysine, 2,6-diaminohexanoic acid.
6555	methionine metabolic process	P	The chemical reactions and pathways involving methionine (2-amino-4-(methylthio)butanoic acid), a sulfur-containing, essential amino acid found in peptide linkage in proteins.
6556	S-adenosylmethionine biosynthetic process	P	The chemical reactions and pathways resulting in the formation of S-adenosylmethionine, S-(5'-adenosyl)-L-methionine, an important intermediate in one-carbon metabolism.
6557	S-adenosylmethioninamine biosynthetic process	P	The chemical reactions and pathways resulting in the formation of S-adenosylmethioninamine, (5-deoxy-5-adenosyl)(3-aminopropyl) methylsulfonium salt.
6558	L-phenylalanine metabolic process	P	The chemical reactions and pathways involving L-phenylalanine, the L-enantiomer of 2-amino-3-phenylpropanoic acid, i.e. (2S)-2-amino-3-phenylpropanoic acid.
6559	L-phenylalanine catabolic process	P	The chemical reactions and pathways resulting in the breakdown of phenylalanine, 2-amino-3-phenylpropanoic acid.
6560	proline metabolic process	P	The chemical reactions and pathways involving proline (pyrrolidine-2-carboxylic acid), a chiral, cyclic, nonessential alpha-amino acid found in peptide linkage in proteins.
6561	proline biosynthetic process	P	The chemical reactions and pathways resulting in the formation of proline (pyrrolidine-2-carboxylic acid), a chiral, cyclic, nonessential alpha-amino acid found in peptide linkage in proteins.
6562	proline catabolic process	P	The chemical reactions and pathways resulting in the breakdown of proline (pyrrolidine-2-carboxylic acid), a chiral, cyclic, nonessential alpha-amino acid found in peptide linkage in proteins.
6563	L-serine metabolic process	P	The chemical reactions and pathways involving L-serine, the L-enantiomer of serine, i.e. (2S)-2-amino-3-hydroxypropanoic acid.
6564	L-serine biosynthetic process	P	The chemical reactions and pathways resulting in the formation of L-serine, the L-enantiomer of serine, i.e. (2S)-2-amino-3-hydroxypropanoic acid.
6565	L-serine catabolic process	P	The chemical reactions and pathways resulting in the breakdown of L-serine, the L-enantiomer of serine, i.e. (2S)-2-amino-3-hydroxypropanoic acid.
6566	threonine metabolic process	P	The chemical reactions and pathways involving threonine (2-amino-3-hydroxybutyric acid), a polar, uncharged, essential amino acid found in peptide linkage in proteins.
6567	threonine catabolic process	P	The chemical reactions and pathways resulting in the breakdown of threonine (2-amino-3-hydroxybutyric acid), a polar, uncharged, essential amino acid found in peptide linkage in proteins.
6568	tryptophan metabolic process	P	The chemical reactions and pathways involving tryptophan, the chiral amino acid 2-amino-3-(1H-indol-3-yl)propanoic acid.
6569	tryptophan catabolic process	P	The chemical reactions and pathways resulting in the breakdown of tryptophan, the chiral amino acid 2-amino-3-(1H-indol-3-yl)propanoic acid.
6570	tyrosine metabolic process	P	The chemical reactions and pathways involving tyrosine, an aromatic amino acid, 2-amino-3-(4-hydroxyphenyl)propanoic acid.
6571	tyrosine biosynthetic process	P	The chemical reactions and pathways resulting in the formation of tyrosine, an aromatic amino acid, 2-amino-3-(4-hydroxyphenyl)propanoic acid.
6572	tyrosine catabolic process	P	The chemical reactions and pathways resulting in the breakdown of tyrosine, an aromatic amino acid, 2-amino-3-(4-hydroxyphenyl)propanoic acid.
6573	valine metabolic process	P	The chemical reactions and pathways involving valine, 2-amino-3-methylbutanoic acid.
6574	valine catabolic process	P	The chemical reactions and pathways resulting in the breakdown of valine, 2-amino-3-methylbutanoic acid.
6575	cellular modified amino acid metabolic process	P	The chemical reactions and pathways involving compounds derived from amino acids, organic acids containing one or more amino substituents.
6576	cellular biogenic amine metabolic process	P	The chemical reactions and pathways occurring at the level of individual cells involving any of a group of naturally occurring, biologically active amines, such as norepinephrine, histamine, and serotonin, many of which act as neurotransmitters.
6577	amino-acid betaine metabolic process	P	The chemical reactions and pathways involving any betaine, the N-trimethyl derivative of an amino acid.
6578	amino-acid betaine biosynthetic process	P	The chemical reactions and pathways resulting in the formation of any betaine, the N-trimethyl derivative of an amino acid.
6579	amino-acid betaine catabolic process	P	The chemical reactions and pathways resulting in the breakdown of any betaine, the N-trimethyl derivative of an amino acid.
6580	ethanolamine metabolic process	P	The chemical reactions and pathways involving ethanolamine (2-aminoethanol), an important water-soluble base of phospholipid (phosphatidylethanolamine).
6581	acetylcholine catabolic process	P	The chemical reactions and pathways resulting in the breakdown of acetylcholine, the acetic acid ester of the organic base choline.
6582	melanin metabolic process	P	The chemical reactions and pathways involving melanins, pigments largely of animal origin. High molecular weight polymers of indole quinone, they are irregular polymeric structures and are divided into three groups: allomelanins in the plant kingdom and eumelanins and phaeomelanins in the animal kingdom.
6583	melanin biosynthetic process from tyrosine	P	The chemical reactions and pathways resulting in the formation of melanin from other compounds, including tyrosine.
6584	catecholamine metabolic process	P	The chemical reactions and pathways involving any of a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine.
6585	dopamine biosynthetic process from tyrosine	P	The chemical reactions and pathways resulting in the formation of dopamine (3,4-dihydroxyphenylethylamine) from L-tyrosine, via the metabolic precursor 3,4-dihydroxy-L-phenylalanine (L-dopa). Dopamine is a catecholamine neurotransmitter and a metabolic precursor of norepinephrine and epinephrine.
6586	indolalkylamine metabolic process	P	The chemical reactions and pathways involving indolalkylamines, indole or indole derivatives containing a primary, secondary, or tertiary amine group.
6587	serotonin biosynthetic process from tryptophan	P	The chemical reactions and pathways resulting in the formation from tryptophan of serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties.
6588	activation of tryptophan 5-monooxygenase activity	P	The process in which the tryptophan 5-monooxygenase enzyme is changed so that it can carry out its enzymatic activity.
6589	octopamine biosynthetic process	P	The chemical reactions and pathways resulting in the formation of octopamine, 1-(p-hydroxyphenyl)-2-aminoethanol. The D enantiomer is about one-tenth as active as norepinephrine and is found in the salivary glands of Octopus and Eledone species.
6590	thyroid hormone generation	P	The formation of either of the compounds secreted by the thyroid gland, mainly thyroxine and triiodothyronine. This is achieved by the iodination and joining of tyrosine molecules to form the precursor thyroglobin, proteolysis of this precursor gives rise to the thyroid hormones.
6591	ornithine metabolic process	P	The chemical reactions and pathways involving ornithine, an amino acid only rarely found in proteins, but which is important in living organisms as an intermediate in the reactions of the urea cycle and in arginine biosynthesis.
6592	ornithine biosynthetic process	P	The chemical reactions and pathways resulting in the formation of ornithine, an amino acid only rarely found in proteins, but which is important in living organisms as an intermediate in the reactions of the urea cycle and in arginine biosynthesis.
6593	ornithine catabolic process	P	The chemical reactions and pathways resulting in the breakdown of ornithine, an amino acid only rarely found in proteins, but which is important in living organisms as an intermediate in the reactions of the urea cycle and in arginine biosynthesis.
6595	polyamine metabolic process	P	The chemical reactions and pathways involving polyamines, any organic compound containing two or more amino groups.
6596	polyamine biosynthetic process	P	The chemical reactions and pathways resulting in the formation of polyamines, any organic compound containing two or more amino groups.
6597	spermine biosynthetic process	P	The chemical reactions and pathways resulting in the formation of spermine, a polybasic amine found in human sperm, in ribosomes and in some viruses and involved in nucleic acid packaging.
6598	polyamine catabolic process	P	The chemical reactions and pathways resulting in the breakdown of polyamines, any organic compound containing two or more amino groups.
6599	phosphagen metabolic process	P	The chemical reactions and pathways involving phosphagen, any of a group of guanidine phosphates that occur in muscle and can be used to regenerate ATP from ADP during muscular contraction.
6600	creatine metabolic process	P	The chemical reactions and pathways involving creatine (N-(aminoiminomethyl)-N-methylglycine), a compound synthesized from the amino acids arginine, glycine, and methionine that occurs in muscle.
6601	creatine biosynthetic process	P	The chemical reactions and pathways resulting in the formation of creatine, N-[amino(imino)methyl]-N-methylglycine. Creatine is formed by a process beginning with amidino group transfer from L-arginine to glycine to form guanidinoacetate, followed by methyl group transfer from S-adenosyl-L-methionine to guanidinoacetate; it is then is phosphorylated to form a pool that stores high energy phosphate for the replenishment of ATP during periods of high, or fluctuating energy demand. In animals, most creatine is transported to and used in muscle.
6602	creatinine catabolic process	P	The chemical reactions and pathways resulting in the breakdown of creatinine, 2-amino-1,5-dihydro-1-methyl-4H-imidazol-4-one, an end product of creatine metabolism and a normal constituent of urine.
6603	phosphocreatine metabolic process	P	The chemical reactions and pathways involving phosphocreatine, a phosphagen of creatine present in high concentration in striated muscle which is synthesized and broken down by creatine phosphokinase to buffer ATP concentration. It acts as an immediate energy reserve for muscle.
6604	phosphoarginine metabolic process	P	The chemical reactions and pathways involving phosphoarginine, a phosphagen of L-arginine with phosphoric acid containing the phosphoamide bond. It is a source of energy in the contraction of muscle in invertebrates, corresponding to phosphocreatine in the muscles of vertebrates.
6605	protein targeting	P	The process of targeting specific proteins to particular regions of the cell, typically membrane-bounded subcellular organelles. Usually requires an organelle specific protein sequence motif.
6606	protein import into nucleus	P	The directed movement of a protein from the cytoplasm to the nucleus.
6607	NLS-bearing protein import into nucleus	P	The directed movement of a protein bearing a nuclear localization signal (NLS) from the cytoplasm into the nucleus, across the nuclear membrane.
6608	snRNP protein import into nucleus	P	The directed movement of a small nuclear ribonucleoprotein from the cytoplasm into the nucleus, across the nuclear membrane.
6609	mRNA-binding (hnRNP) protein import into nucleus	P	The directed movement of a heterogeneous nuclear ribonucleoprotein from the cytoplasm into the nucleus, across the nuclear membrane.
6610	ribosomal protein import into nucleus	P	The directed movement of a ribosomal protein from the cytoplasm into the nucleus, across the nuclear membrane.
6611	protein export from nucleus	P	The directed movement of a protein from the nucleus into the cytoplasm.
6612	protein targeting to membrane	P	The process of directing proteins towards a membrane, usually using signals contained within the protein.
6613	cotranslational protein targeting to membrane	P	The targeting of proteins to a membrane that occurs during translation. The transport of most secretory proteins, particularly those with more than 100 amino acids, into the endoplasmic reticulum lumen occurs in this manner, as does the import of some proteins into mitochondria.
6614	SRP-dependent cotranslational protein targeting to membrane	P	The targeting of proteins to a membrane that occurs during translation and is dependent upon two key components, the signal-recognition particle (SRP) and the SRP receptor. SRP is a cytosolic particle that transiently binds to the endoplasmic reticulum (ER) signal sequence in a nascent protein, to the large ribosomal unit, and to the SRP receptor in the ER membrane.
6615	SRP-dependent cotranslational protein targeting to membrane, docking	P	The process in which an SRP-bound ribosome forms a complex with the SRP receptor in the ER membrane, allowing the ribosome to bind to the membrane, during cotranslational membrane targeting.
6616	SRP-dependent cotranslational protein targeting to membrane, translocation	P	The process during cotranslational membrane targeting wherein proteins move across a membrane. SRP and its receptor initiate the transfer of the nascent chain across the endoplasmic reticulum (ER) membrane; they then dissociate from the chain, which is transferred to a set of transmembrane proteins, collectively called the translocon. Once the nascent chain translocon complex is assembled, the elongating chain passes directly from the large ribosomal subunit into the centers of the translocon, a protein-lined channel within the membrane. The growing chain is never exposed to the cytosol and does not fold until it reaches the ER lumen.
6617	SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition	P	The process in which SRP binds to the signal peptide in a nascent protein, causing protein elongation to pause, during cotranslational membrane targeting.
6618	SRP-dependent cotranslational protein targeting to membrane, signal sequence processing	P	The removal of the signal peptide from a nascent protein during cotranslational membrane targeting.
6620	posttranslational protein targeting to membrane	P	The targeting of proteins to a membrane that occurs after their translation. Some secretory proteins exhibit posttranslational transport into the endoplasmic reticulum (ER) lumen: they are synthesized in their entirety on free cytosolic ribosomes and then released into the cytosol, where they are bound by chaperones which keep them in an unfolded state, and subsequently are translocated across the ER membrane.
6621	protein retention in ER lumen	P	The retention in the endoplasmic reticulum (ER) lumen of soluble resident proteins. Sorting receptors retrieve proteins with ER localization signals, such as KDEL and HDEL sequences or some transmembrane domains, that have escaped to the cis-Golgi network and return them to the ER. Abnormally folded proteins and unassembled subunits are also selectively retained in the ER.
6622	protein targeting to lysosome	P	The process of directing proteins towards the lysosome using signals contained within the protein.
6623	protein targeting to vacuole	P	The process of directing proteins towards the vacuole, usually using signals contained within the protein.
6624	vacuolar protein processing	P	Protein processing that takes place in the vacuole. Most protein processing in the vacuole represents proteolytic cleavage of precursors to form active enzymes.
6625	protein targeting to peroxisome	P	The process of directing proteins towards the peroxisome, usually using signals contained within the protein.
6626	protein targeting to mitochondrion	P	The process of directing proteins towards and into the mitochondrion, usually mediated by mitochondrial proteins that recognize signals contained within the imported protein.
6627	protein processing involved in protein targeting to mitochondrion	P	The cleavage of peptide bonds in proteins, usually near the N terminus, contributing to the process of import into the mitochondrion. Several different peptidases mediate cleavage of proteins destined for different mitochondrial compartments.
6629	lipid metabolic process	P	The chemical reactions and pathways involving lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent. Includes fatty acids; neutral fats, other fatty-acid esters, and soaps; long-chain (fatty) alcohols and waxes; sphingoids and other long-chain bases; glycolipids, phospholipids and sphingolipids; and carotenes, polyprenols, sterols, terpenes and other isoprenoids.
6631	fatty acid metabolic process	P	The chemical reactions and pathways involving fatty acids, aliphatic monocarboxylic acids liberated from naturally occurring fats and oils by hydrolysis.
6633	fatty acid biosynthetic process	P	The chemical reactions and pathways resulting in the formation of a fatty acid, any of the aliphatic monocarboxylic acids that can be liberated by hydrolysis from naturally occurring fats and oils. Fatty acids are predominantly straight-chain acids of 4 to 24 carbon atoms, which may be saturated or unsaturated; branched fatty acids and hydroxy fatty acids also occur, and very long chain acids of over 30 carbons are found in waxes.
6634	hexadecanal biosynthetic process	P	The chemical reactions and pathways resulting in the formation of hexadecanal, the C16 straight chain aldehyde.
6635	fatty acid beta-oxidation	P	A fatty acid oxidation process that results in the complete oxidation of a long-chain fatty acid. Fatty acid beta-oxidation begins with the addition of coenzyme A to a fatty acid, and occurs by successive cycles of reactions during each of which the fatty acid is shortened by a two-carbon fragment removed as acetyl coenzyme A; the cycle continues until only two or three carbons remain (as acetyl-CoA or propionyl-CoA respectively).
6636	unsaturated fatty acid biosynthetic process	P	The chemical reactions and pathways resulting in the formation of an unsaturated fatty acid, any fatty acid containing one or more double bonds between carbon atoms.
6637	acyl-CoA metabolic process	P	The chemical reactions and pathways involving acyl-CoA, any derivative of coenzyme A in which the sulfhydryl group is in thiolester linkage with an acyl group.
6638	neutral lipid metabolic process	P	The chemical reactions and pathways involving neutral lipids, lipids only soluble in solvents of very low polarity.
6639	acylglycerol metabolic process	P	The chemical reactions and pathways involving acylglycerol, any mono-, di- or triester of glycerol with (one or more) fatty acids.
6640	monoacylglycerol biosynthetic process	P	The chemical reactions and pathways resulting in the formation of monoacylglycerol, any ester of glycerol in which any one of its hydroxyl groups has been acylated with a fatty acid, the other being non-esterified.
6641	triglyceride metabolic process	P	The chemical reactions and pathways involving triglyceride, any triester of glycerol. The three fatty acid residues may all be the same or differ in any permutation. Triglycerides are important components of plant oils, animal fats and animal plasma lipoproteins.
6642	triglyceride mobilization	P	The release of triglycerides, any triester of glycerol, from storage within cells or tissues, making them available for metabolism.
6643	membrane lipid metabolic process	P	The chemical reactions and pathways involving membrane lipids, any lipid found in or associated with a biological membrane.
6644	phospholipid metabolic process	P	The chemical reactions and pathways involving phospholipids, any lipid containing phosphoric acid as a mono- or diester.
6646	phosphatidylethanolamine biosynthetic process	P	The chemical reactions and pathways resulting in the formation of phosphatidylethanolamine, any of a class of glycerophospholipids in which a phosphatidyl group is esterified to the hydroxyl group of ethanolamine.
6647	phosphatidyl-N-monomethylethanolamine biosynthetic process	P	The chemical reactions and pathways involving phosphatidyl-N-monomethylethanolamine (PMME), a derivative of phosphatidylethanolamine with a methylated amine group.
6648	dihydrosphingosine-1-P pathway	P	A phosphatidylethanolamine biosynthetic process that proceeds via the enzymatic action of dihydrosphingosine phosphate lyase.
6649	phospholipid transfer to membrane	P	The transfer of a phospholipid from its site of synthesis to the plasma membrane.
6650	glycerophospholipid metabolic process	P	The chemical reactions and pathways involving glycerophospholipids, any derivative of glycerophosphate that contains at least one O-acyl, O-alkyl, or O-alkenyl group attached to the glycerol residue.
6651	diacylglycerol biosynthetic process	P	The chemical reactions and pathways resulting in the formation of diacylglycerol, a glyceride in which any two of the R groups (positions not specified) are acyl groups while the remaining R group can be either H or an alkyl group.
6653	1,2-diacyl-sn-glycero-3-phosphocholine metabolic process	P	The chemical reactions and pathways involving any 1,2-diacyl-sn-glycero-3-phosphocholine, the compounds most commonly designated lecithin.
6654	phosphatidic acid biosynthetic process	P	The chemical reactions and pathways resulting in the formation of phosphatidic acid, any derivative of glycerol phosphate in which both the remaining hydroxyl groups of the glycerol moiety are esterified with fatty acids.
6655	phosphatidylglycerol biosynthetic process	P	The chemical reactions and pathways resulting in the formation of phosphatidylglycerols, any of a class of phospholipids in which the phosphatidyl group is esterified to the hydroxyl group of glycerol.
6656	phosphatidylcholine biosynthetic process	P	The chemical reactions and pathways resulting in the formation of phosphatidylcholines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of choline.
6657	CDP-choline pathway	P	The phosphatidylcholine biosynthetic process that begins with the phosphorylation of choline and ends with the combination of CDP-choline with diacylglycerol to form phosphatidylcholine.
6658	phosphatidylserine metabolic process	P	The chemical reactions and pathways involving phosphatidylserines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of L-serine. They are important constituents of cell membranes.
6659	phosphatidylserine biosynthetic process	P	The chemical reactions and pathways resulting in the formation of phosphatidylserines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of L-serine.
6660	phosphatidylserine catabolic process	P	The chemical reactions and pathways resulting in the breakdown of phosphatidylserines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of L-serine.
6661	phosphatidylinositol biosynthetic process	P	The chemical reactions and pathways resulting in the formation of phosphatidylinositol, any glycophospholipid in which the sn-glycerol 3-phosphate residue is esterified to the 1-hydroxyl group of 1D-myo-inositol.
6662	glycerol ether metabolic process	P	The chemical reactions and pathways involving glycerol ethers, any anhydride formed between two organic hydroxy compounds, one of which is glycerol.
6663	platelet activating factor biosynthetic process	P	The chemical reactions and pathways resulting in the formation of platelet activating factor, 1-O-alkyl-2-acetyl-sn-glycerol 3-phosphocholine, where alkyl = hexadecyl or octadecyl. Platelet activating factor is an inflammatory mediator released from a variety of cells in response to various stimuli.
6664	glycolipid metabolic process	P	The chemical reactions and pathways involving glycolipids, a class of 1,2-di-O-acylglycerols joined at oxygen 3 by a glycosidic linkage to a carbohydrate part (usually a mono-, di- or tri-saccharide). Some substances classified as bacterial glycolipids have the sugar group acylated by one or more fatty acids and the glycerol group may be absent.
6665	sphingolipid metabolic process	P	The chemical reactions and pathways involving sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid).
6666	3-keto-sphinganine metabolic process	P	The chemical reactions and pathways involving 3-keto-sphinganine, a derivative of sphinganine with a ketone group at C3. It is an intermediate in the synthesis of sphingosine.
6667	sphinganine metabolic process	P	The chemical reactions and pathways involving sphinganine, D-erythro-2-amino-1,3-octadecanediol.
6668	sphinganine-1-phosphate metabolic process	P	The chemical reactions and pathways involving sphinganine-1-phosphate, the phosphorylated derivative of D-erythro-2-amino-1,3-octadecanediol.
6669	sphinganine-1-phosphate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of sphinganine-1-phosphate, the phosphorylated derivative of D-erythro-2-amino-1,3-octadecanediol.
6670	sphingosine metabolic process	P	The chemical reactions and pathways involving sphingosine (sphing-4-enine), trans-D-erytho-2-amino-octadec-4-ene-1,3-diol, a long chain amino diol sphingoid base that occurs in most sphingolipids in animal tissues.
6671	phytosphingosine metabolic process	P	The chemical reactions and pathways involving phytosphingosine, (2S,3S,4R)-2-aminooctadecane-1,3,4-triol, a constituent of many plant sphingolipids.
6672	ceramide metabolic process	P	The chemical reactions and pathways involving ceramides, any N-acylated sphingoid.
6673	inositolphosphoceramide metabolic process	P	The chemical reactions and pathways involving inositolphosphoceramides, any lipid with a phosphodiester bridge between an inositol residue and the ceramide group.
6675	mannosyl-inositol phosphorylceramide metabolic process	P	The chemical reactions and pathways involving mannosyl-inositol phosphorylceramide, any lipid with a phosphodiester bridge between an inositol residue and the ceramide group which contains a phosphoryl (-P(O)=) groups and a mannose derivative.
6676	mannosyl diphosphorylinositol ceramide metabolic process	P	The chemical reactions and pathways involving mannosyl diphosphorylinositol ceramide, any lipid with a phosphodiester bridge between an inositol residue and the ceramide group which contains two phosphoryl (-P(O)=) groups and a mannose derivative.
6677	glycosylceramide metabolic process	P	The chemical reactions and pathways involving glycosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of a monosaccharide (or derivative) by a ceramide group.
6678	glucosylceramide metabolic process	P	The chemical reactions and pathways involving glucosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of glucose by a ceramide group. They are neutral glycolipids containing equimolar amounts of fatty acid, glucose, and sphingosine or a sphingosine derivative.
6679	glucosylceramide biosynthetic process	P	The chemical reactions and pathways resulting in the formation of glucosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of glucose by a ceramide group.
6680	glucosylceramide catabolic process	P	The chemical reactions and pathways resulting in the breakdown of glucosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of glucose by a ceramide group.
6681	galactosylceramide metabolic process	P	The chemical reactions and pathways involving galactosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of galactose by a ceramide group.
6682	galactosylceramide biosynthetic process	P	The chemical reactions and pathways resulting in the formation of galactosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of galactose by a ceramide group.
6683	galactosylceramide catabolic process	P	The chemical reactions and pathways resulting in the breakdown of galactosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of galactose by a ceramide group.
6684	sphingomyelin metabolic process	P	The chemical reactions and pathways involving sphingomyelin, N-acyl-4-sphingenyl-1-O-phosphorylcholine, any of a class of phospholipids in which the amino group of sphingosine is in amide linkage with one of several fatty acids, while the terminal hydroxyl group of sphingosine is esterified to phosphorylcholine.
6685	sphingomyelin catabolic process	P	The chemical reactions and pathways resulting in the breakdown of sphingomyelin, N-acyl-4-sphingenyl-1-O-phosphorylcholine.
6686	sphingomyelin biosynthetic process	P	The chemical reactions and pathways resulting in the formation of sphingomyelin, N-acyl-4-sphingenyl-1-O-phosphorylcholine.
6687	glycosphingolipid metabolic process	P	The chemical reactions and pathways involving glycosphingolipids, any compound with residues of sphingoid and at least one monosaccharide.
6688	glycosphingolipid biosynthetic process	P	The chemical reactions and pathways resulting in the formation of glycosphingolipid, a compound with residues of sphingoid and at least one monosaccharide.
6689	ganglioside catabolic process	P	The chemical reactions and pathways resulting in the breakdown of ganglioside, a ceramide oligosaccharide carrying, in addition to other sugar residues, one or more sialic residues.
6690	icosanoid metabolic process	P	The chemical reactions and pathways involving icosanoids, any of a group of C20 polyunsaturated fatty acids.
6691	leukotriene metabolic process	P	The chemical reactions and pathways involving leukotriene, a pharmacologically active substance derived from a polyunsaturated fatty acid, such as arachidonic acid.
6692	prostanoid metabolic process	P	The chemical reactions and pathways involving prostanoids, any compound based on or derived from the prostanoate structure.
6693	prostaglandin metabolic process	P	The chemical reactions and pathways involving prostaglandins, any of a group of biologically active metabolites which contain a cyclopentane ring due to the formation of a bond between two carbons of a fatty acid. They have a wide range of biological activities.
6694	steroid biosynthetic process	P	The chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus; includes de novo formation and steroid interconversion by modification.
6695	cholesterol biosynthetic process	P	The chemical reactions and pathways resulting in the formation of cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones.
6696	ergosterol biosynthetic process	P	The chemical reactions and pathways resulting in the formation of ergosterol, (22E)-ergosta-5,7,22-trien-3-beta-ol, a sterol found in ergot, yeast and moulds.
6697	ecdysone biosynthetic process	P	The chemical reactions and pathways resulting in the formation of ecdysone, (22R)-2-beta,3-beta,14,22,25-pentahydroxycholest-7-en-6-one, an ecdysteroid found in insects.
6699	bile acid biosynthetic process	P	The chemical reactions and pathways resulting in the formation of bile acids, any of a group of steroid carboxylic acids occurring in bile.
6700	C21-steroid hormone biosynthetic process	P	The chemical reactions and pathways resulting in the formation of C21-steroid hormones, steroid compounds containing 21 carbons which function as hormones.
6701	progesterone biosynthetic process	P	The chemical reactions and pathways resulting in the formation of progesterone, a steroid hormone produced in the ovary which prepares and maintains the uterus for pregnancy. Also found in plants.
6702	androgen biosynthetic process	P	The chemical reactions and pathways resulting in the formation of androgens, C19 steroid hormones that can stimulate the development of male sexual characteristics.
6703	estrogen biosynthetic process	P	The chemical reactions and pathways resulting in the formation of estrogens, C18 steroid hormones that can stimulate the development of female sexual characteristics. Also found in plants.
6704	glucocorticoid biosynthetic process	P	The chemical reactions and pathways resulting in the formation of glucocorticoids, hormonal C21 corticosteroids synthesized from cholesterol.
6705	mineralocorticoid biosynthetic process	P	The chemical reactions and pathways resulting in the formation of mineralocorticoids, hormonal C21 corticosteroids synthesized from cholesterol.
6706	steroid catabolic process	P	The chemical reactions and pathways resulting in the breakdown of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus.
6707	cholesterol catabolic process	P	The chemical reactions and pathways resulting in the breakdown of cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones.
6708	ecdysone catabolic process	P	The chemical reactions and pathways resulting in the breakdown of ecdysone, (22R)-2-beta,3-beta,14,22,25-pentahydroxycholest-7-en-6-one, an ecdysteroid found in insects.
6709	progesterone catabolic process	P	The chemical reactions and pathways resulting in the breakdown of progesterone, a steroid hormone produced in the ovary which prepares and maintains the uterus for pregnancy. Also found in plants.
6710	androgen catabolic process	P	The chemical reactions and pathways resulting in the breakdown of androgens, C19 steroid hormones that can stimulate the development of male sexual characteristics.
6711	estrogen catabolic process	P	The chemical reactions and pathways resulting in the breakdown of estrogens, C18 steroid hormones that can stimulate the development of female sexual characteristics. Also found in plants.
6712	mineralocorticoid catabolic process	P	The chemical reactions and pathways resulting in the breakdown of mineralocorticoids, hormonal C21 corticosteroids synthesized from cholesterol.
6713	glucocorticoid catabolic process	P	The chemical reactions and pathways resulting in the breakdown of glucocorticoids, hormonal C21 corticosteroids synthesized from cholesterol.
6714	sesquiterpenoid metabolic process	P	The chemical reactions and pathways involving sesquiterpenoid compounds, terpenoids with three isoprene units.
6715	farnesol biosynthetic process	P	The chemical reactions and pathways resulting in the formation of the sesquiterpenoid alcohol farnesol, 3,7,11-trimethyl-2,6,10,dodecatrien-1-ol.
6716	juvenile hormone metabolic process	P	The chemical reactions and pathways involving juvenile hormones, the three sesquiterpenoid derivatives that function to maintain the larval state of insects at molting and that may be required for other processes, e.g. oogenesis.
6718	juvenile hormone biosynthetic process	P	The chemical reactions and pathways resulting in the formation of juvenile hormones, the three sesquiterpenoid derivatives that function to maintain the larval state of insects at molting and that may be required for other processes, e.g. oogenesis.
6719	juvenile hormone catabolic process	P	The chemical reactions and pathways resulting in the breakdown of juvenile hormones, the three sesquiterpenoid derivatives that function to maintain the larval state of insects at molting and that may be required for other processes, e.g. oogenesis.
6720	isoprenoid metabolic process	P	The chemical reactions and pathways involving isoprenoid compounds, isoprene (2-methylbuta-1,3-diene) or compounds containing or derived from linked isoprene (3-methyl-2-butenylene) residues.
6721	terpenoid metabolic process	P	The chemical reactions and pathways involving terpenoids, any member of a class of compounds characterized by an isoprenoid chemical structure and including derivatives with various functional groups.
6722	triterpenoid metabolic process	P	The chemical reactions and pathways involving triterpenoid compounds, terpenoids with six isoprene units.
6723	cuticle hydrocarbon biosynthetic process	P	The chemical reactions and pathways resulting in the formation of hydrocarbons that make up the cuticle, the outer layer of some animals and plants, which acts to prevent water loss.
6725	cellular aromatic compound metabolic process	P	The chemical reactions and pathways involving aromatic compounds, any organic compound characterized by one or more planar rings, each of which contains conjugated double bonds and delocalized pi electrons, as carried out by individual cells.
6726	eye pigment biosynthetic process	P	The chemical reactions and pathways resulting in the formation of eye pigments, any general or particular coloring matter in living organisms, found or utilized in the eye.
6727	ommochrome biosynthetic process	P	The chemical reactions and pathways resulting in the formation of ommochromes, any of a large group of natural polycyclic pigments commonly found in the Arthropoda, particularly in the ommatidia of the compound eye.
6728	pteridine biosynthetic process	P	The chemical reactions and pathways resulting in the formation of pteridine, pyrazino(2,3-dipyrimidine), the parent structure of pterins and the pteroyl group.
6729	tetrahydrobiopterin biosynthetic process	P	The chemical reactions and pathways resulting in the formation of tetrahydrobiopterin, the reduced form of biopterin (2-amino-4-hydroxy-6-(1,2-dihydroxypropyl)-pteridine). It functions as a hydroxylation coenzyme, e.g. in the conversion of phenylalanine to tyrosine.
6730	one-carbon metabolic process	P	The chemical reactions and pathways involving the transfer of one-carbon units in various oxidation states.
6732	coenzyme metabolic process	P	The chemical reactions and pathways involving coenzymes, any of various nonprotein organic cofactors that are required, in addition to an enzyme and a substrate, for an enzymatic reaction to proceed.
6733	oxidoreduction coenzyme metabolic process	P	The chemical reactions and pathways involving coenzymes that are required, in addition to an enzyme and a substrate, for an oxidoreductase reaction to proceed.
6734	NADH metabolic process	P	The chemical reactions and pathways involving reduced nicotinamide adenine dinucleotide (NADH), a coenzyme present in most living cells and derived from the B vitamin nicotinic acid.
6735	NADH regeneration	P	A metabolic process that generates a pool of NADH by the reduction of NAD+.
6738	nicotinamide riboside catabolic process	P	The chemical reactions and pathways resulting in the breakdown of nicotinamide riboside, the product of the formation of a glycosidic bond between ribose and nicotinamide.
6739	NADP metabolic process	P	The chemical reactions and pathways involving nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions; metabolism may be of either the oxidized form, NADP, or the reduced form, NADPH.
6740	NADPH regeneration	P	A metabolic process that generates a pool of NADPH by the reduction of NADP+.
6741	NADP biosynthetic process	P	The chemical reactions and pathways resulting in the formation of nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions; biosynthesis may be of either the oxidized form, NADP, or the reduced form, NADPH.
6742	NADP catabolic process	P	The chemical reactions and pathways resulting in the breakdown of nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions; catabolism may be of either the oxidized form, NADP, or the reduced form, NADPH.
6743	ubiquinone metabolic process	P	The chemical reactions and pathways involving ubiquinone, a lipid-soluble electron-transporting coenzyme.
6744	ubiquinone biosynthetic process	P	The chemical reactions and pathways resulting in the formation of ubiquinone, a lipid-soluble electron-transporting coenzyme.
6746	FADH2 metabolic process	P	The chemical reactions and pathways involving the reduced form of flavin adenine dinucleotide.
6747	FAD biosynthetic process	P	The chemical reactions and pathways resulting in the formation of FAD, the oxidized form of flavin-adenine dinucleotide.
6748	lipoamide metabolic process	P	The chemical reactions and pathways involving lipoamide, the functional form of lipoic acid in which the carboxyl group is attached to protein by an amide linkage to a lysine amino group.
6749	glutathione metabolic process	P	The chemical reactions and pathways involving glutathione, the tripeptide glutamylcysteinylglycine, which acts as a coenzyme for some enzymes and as an antioxidant in the protection of sulfhydryl groups in enzymes and other proteins; it has a specific role in the reduction of hydrogen peroxide (H2O2) and oxidized ascorbate, and it participates in the gamma-glutamyl cycle.
6750	glutathione biosynthetic process	P	The chemical reactions and pathways resulting in the formation of glutathione, the tripeptide glutamylcysteinylglycine, which acts as a coenzyme for some enzymes and as an antioxidant in the protection of sulfhydryl groups in enzymes and other proteins.
6751	glutathione catabolic process	P	The chemical reactions and pathways resulting in the breakdown of glutathione, the tripeptide glutamylcysteinylglycine, which acts as a coenzyme for some enzymes and as an antioxidant in the protection of sulfhydryl groups in enzymes and other proteins.
6753	nucleoside phosphate metabolic process	P	The chemical reactions and pathways involving any phosphorylated nucleoside.
6754	ATP biosynthetic process	P	The chemical reactions and pathways resulting in the formation of ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
6756	AMP phosphorylation	P	The process of introducing a phosphate group into AMP, adenosine monophosphate, to produce ADP. Addition of two phosphate groups produces ATP.
6757	ATP generation from ADP	P	The process of introducing a phosphate group into ADP, adenosine diphosphate, to produce ATP.
6760	folic acid-containing compound metabolic process	P	The chemical reactions and pathways involving a folic acid-containing compound, i.e. any of a group of heterocyclic compounds based on the pteroic acid skeleton conjugated with one or more L-glutamic acid or L-glutamate units.
6761	dihydrofolate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of dihydrofolate, the dihydroxylated derivative of folate.
6766	vitamin metabolic process	P	The chemical reactions and pathways involving vitamins. Vitamin is a general term for a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body. Vitamins may be water-soluble or fat-soluble and usually serve as components of coenzyme systems.
6767	water-soluble vitamin metabolic process	P	The chemical reactions and pathways involving any of a diverse group of vitamins that are soluble in water.
6768	biotin metabolic process	P	The chemical reactions and pathways involving biotin, cis-tetrahydro-2-oxothieno(3,4-d)imidazoline-4-valeric acid; the (+) enantiomer is very widely distributed in cells and serves as a carrier in a number of enzymatic beta-carboxylation reactions.
6769	nicotinamide metabolic process	P	The chemical reactions and pathways involving nicotinamide, pyridine-3-carboxamide, the amide of nicotinic acid. It is a member of the B complex of vitamins and occurs widely in living organisms.
6771	riboflavin metabolic process	P	The chemical reactions and pathways involving riboflavin (vitamin B2), the precursor for the coenzymes flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD).
6772	thiamine metabolic process	P	The chemical reactions and pathways involving thiamine (vitamin B1), a water soluble vitamin present in fresh vegetables and meats, especially liver.
6775	fat-soluble vitamin metabolic process	P	The chemical reactions and pathways involving of any of a diverse group of vitamins that are soluble in organic solvents and relatively insoluble in water.
6776	vitamin A metabolic process	P	The chemical reactions and pathways involving any of the vitamin A compounds, retinol, retinal (retinaldehyde) and retinoic acid, all of which are derivatives of beta-carotene.
6777	Mo-molybdopterin cofactor biosynthetic process	P	The chemical reactions and pathways resulting in the formation of the Mo-molybdopterin cofactor, essential for the catalytic activity of some enzymes. The cofactor consists of a mononuclear molybdenum (Mo) ion coordinated by one or two molybdopterin ligands.
6778	porphyrin-containing compound metabolic process	P	The chemical reactions and pathways involving any member of a large group of derivatives or analogs of porphyrin. Porphyrins consists of a ring of four pyrrole nuclei linked each to the next at their alpha positions through a methine group.
6779	porphyrin-containing compound biosynthetic process	P	The chemical reactions and pathways resulting in the formation of any member of a large group of derivatives or analogs of porphyrin. Porphyrin consists of a ring of four pyrrole nuclei linked each to the next at their alpha positions through a methine group.
6780	uroporphyrinogen III biosynthetic process	P	The chemical reactions and pathways resulting in the formation of uroporphyrinogen III.
6781	succinyl-CoA pathway	P	The chemical reactions that utilize succinyl-CoA in the synthesis of protoporphyrin IX.
6782	protoporphyrinogen IX biosynthetic process	P	The chemical reactions and pathways resulting in the formation of protoporphyrinogen IX.
6783	heme biosynthetic process	P	The chemical reactions and pathways resulting in the formation of heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring, from less complex precursors.
6784	heme a biosynthetic process	P	The chemical reactions and pathways resulting in the formation of heme a, a derivative of heme found in cytochrome aa3.
6785	heme b biosynthetic process	P	The chemical reactions and pathways resulting in the formation of heme b, a Fe(II) porphyrin complex readily isolated from the hemoglobin of beef blood, but also found in other proteins including other hemoglobins, myoglobins, cytochromes P-450, catalases, peroxidases as well as b type cytochromes.
6786	heme c biosynthetic process	P	The chemical reactions and pathways resulting in the formation of heme c, a derivative of heme found in cytochromes c, b4, and f.
6787	porphyrin-containing compound catabolic process	P	The chemical reactions and pathways resulting in the breakdown of any member of a large group of derivatives or analogs of porphyrin. Porphyrin consists of a ring of four pyrrole nuclei linked each to the next at their alpha positions through a methine group.
6788	heme oxidation	P	The chemical reactions and pathways resulting in the loss of electrons from one or more atoms in heme.
6789	bilirubin conjugation	P	The chemical reactions and pathways resulting in the formation of bilirubin monoglucuronide or bilirubin diglucuronide, water-soluble derivatives of bilirubin.
6790	sulfur compound metabolic process	P	The chemical reactions and pathways involving the nonmetallic element sulfur or compounds that contain sulfur, such as the amino acids methionine and cysteine or the tripeptide glutathione.
6791	sulfur utilization	P	A series of processes that forms an integrated mechanism by which a cell or an organism detects the depletion of primary sulfur sources and then activates genes to scavenge the last traces of the primary sulfur source and to transport and metabolize alternate sulfur sources. The utilization process begins when the cell or organism detects sulfur levels, includes the activation of genes whose products detect, transport or metabolize sulfur-containing compounds, and ends when the sulfur is incorporated into the cell or organism's metabolism.
6792	regulation of sulfur utilization	P	Any process that modulates the frequency, rate or extent of sulfur utilization.
6793	phosphorus metabolic process	P	The chemical reactions and pathways involving the nonmetallic element phosphorus or compounds that contain phosphorus, usually in the form of a phosphate group (PO4).
6794	phosphorus utilization	P	A series of processes that forms an integrated mechanism by which a cell or an organism detects the depletion of primary phosphorus source and then activates genes to scavenge the last traces of the primary phosphorus source and to transport and metabolize alternative phosphorus sources. The utilization process begins when the cell or organism detects phosphorus levels, includes the phosphorus-containing substances, and ends when phosphorus is incorporated into the cell or organism's metabolism.
6795	regulation of phosphorus utilization	P	Any process that modulates the frequency, rate or extent of phosphorus utilization.
6796	phosphate-containing compound metabolic process	P	The chemical reactions and pathways involving the phosphate group, the anion or salt of any phosphoric acid.
6797	polyphosphate metabolic process	P	The chemical reactions and pathways involving a polyphosphate, the anion or salt of polyphosphoric acid.
6798	polyphosphate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of a polyphosphate, the anion or salt of polyphosphoric acid.
6799	polyphosphate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of a polyphosphate, the anion or salt of polyphosphoric acid.
6801	superoxide metabolic process	P	The chemical reactions and pathways involving superoxide, the superoxide anion O2- (superoxide free radical), or any compound containing this species.
6805	xenobiotic metabolic process	P	The chemical reactions and pathways involving a xenobiotic compound, a compound foreign to living organisms. Used of chemical compounds, e.g. a xenobiotic chemical, such as a pesticide.
6807	nitrogen compound metabolic process	P	The chemical reactions and pathways involving organic or inorganic compounds that contain nitrogen, including (but not limited to) nitrogen fixation, nitrification, denitrification, assimilatory/dissimilatory nitrate reduction and the interconversion of nitrogenous organic matter and ammonium.
6808	regulation of nitrogen utilization	P	Any process that modulates the frequency, rate or extent of nitrogen utilization.
6809	nitric oxide biosynthetic process	P	The chemical reactions and pathways resulting in the formation of nitric oxide, nitrogen monoxide (NO), a colorless gas only slightly soluble in water.
6810	transport	P	The directed movement of substances (such as macromolecules, small molecules, ions) or cellular components (such as complexes and organelles) into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter, pore or motor protein.
6811	ion transport	P	The directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
6812	cation transport	P	The directed movement of cations, atoms or small molecules with a net positive charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
6813	potassium ion transport	P	The directed movement of potassium ions (K+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
6814	sodium ion transport	P	The directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
6816	calcium ion transport	P	The directed movement of calcium (Ca) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
6817	phosphate ion transport	P	The directed movement of phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
6818	hydrogen transport	P	The directed movement of hydrogen (H2 or H+), into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
6820	anion transport	P	The directed movement of anions, atoms or small molecules with a net negative charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
6821	chloride transport	P	The directed movement of chloride into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
6824	cobalt ion transport	P	The directed movement of cobalt (Co) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
6825	copper ion transport	P	The directed movement of copper (Cu) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
6826	iron ion transport	P	The directed movement of iron (Fe) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
6827	high-affinity iron ion transmembrane transport	P	A process in which an iron ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.
6828	manganese ion transport	P	The directed movement of manganese (Mn) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
6829	zinc II ion transport	P	The directed movement of zinc (Zn II) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
6830	high-affinity zinc II ion transport	P	The directed, high-affinity movement of zinc (Zn II) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.
6831	low-affinity zinc II ion transport	P	The directed, low-affinity movement of zinc (Zn II) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. In low-affinity transport the transporter is able to bind the solute only if it is only present at very low concentrations.
6833	water transport	P	The directed movement of water (H2O) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
6835	dicarboxylic acid transport	P	The directed movement of dicarboxylic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
6836	neurotransmitter transport	P	The directed movement of a neurotransmitter into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Neurotransmitters are any chemical substance that is capable of transmitting (or inhibiting the transmission of) a nerve impulse from a neuron to another cell.
6837	serotonin transport	P	The directed movement of serotonin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Serotonin (5-hydroxytryptamine) is a monoamine neurotransmitter occurring in the peripheral and central nervous systems.
6839	mitochondrial transport	P	Transport of substances into, out of or within a mitochondrion.
6842	tricarboxylic acid transport	P	The directed movement of tricarboxylic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
6843	mitochondrial citrate transport	P	The directed movement of citrate, 2-hydroxy-1,2,3-propanetricarboyxlate, into, out of or within a mitochondrion.
6844	acyl carnitine transport	P	The directed movement of acyl carnitine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Acyl carnitine is the condensation product of a carboxylic acid and carnitine and is the transport form for a fatty acid crossing the mitochondrial membrane.
6846	acetate transport	P	The directed movement of acetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
6847	plasma membrane acetate transport	P	The directed movement of acetate across a plasma membrane.
6848	pyruvate transport	P	The directed movement of pyruvate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
6849	plasma membrane pyruvate transport	P	The directed movement of pyruvate, 2-oxopropanoate, across a plasma membrane.
6850	mitochondrial pyruvate transport	P	The directed movement of pyruvate, 2-oxopropanoate, into, out of or within a mitochondrion.
6851	mitochondrial calcium ion transport	P	The directed movement of calcium ions (Ca2+) into, out of or within a mitochondrion.
6853	carnitine shuttle	P	The transfer of acyl groups to and from acyl-CoA molecules to form O-acylcarnitine, which can exchange across the mitochondrial inner membrane with unacylated carnitine.
6855	drug transmembrane transport	P	The process in which a drug is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.
6856	eye pigment precursor transport	P	The directed movement of eye pigment precursors, the inactive forms of visual pigments, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
6857	oligopeptide transport	P	The directed movement of oligopeptides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Oligopeptides are molecules that contain a small number (2 to 20) of amino-acid residues connected by peptide linkages.
6858	extracellular transport	P	The transport of substances that occurs outside cells.
6859	extracellular carbohydrate transport	P	The directed extracellular movement of carbohydrates.
6860	extracellular amino acid transport	P	The directed extracellular movement of amino acids.
6862	nucleotide transport	P	The directed movement of a nucleotide, any compound consisting of a nucleoside that is esterified with (ortho)phosphate, into, out of or within a cell.
6863	purine nucleobase transport	P	The directed movement of purine bases, one of the two classes of nitrogen-containing ring compounds found in DNA and RNA, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
6864	pyrimidine nucleotide transport	P	The directed movement of a pyrimidine nucleotide, any compound consisting of a pyrimidine nucleoside esterified with (ortho)phosphate, into, out of or within a cell.
6865	amino acid transport	P	The directed movement of amino acids, organic acids containing one or more amino substituents, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
6867	asparagine transport	P	The directed movement of asparagine, alpha-aminosuccinamic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
6868	glutamine transport	P	The directed movement of glutamine, 2-amino-4-carbamoylbutanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
6869	lipid transport	P	The directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Lipids are compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent.
6873	cellular ion homeostasis	P	Any process involved in the maintenance of an internal steady state of ions at the level of a cell.
6874	cellular calcium ion homeostasis	P	Any process involved in the maintenance of an internal steady state of calcium ions at the level of a cell.
6875	cellular metal ion homeostasis	P	Any process involved in the maintenance of an internal steady state of metal ions at the level of a cell.
6876	cellular cadmium ion homeostasis	P	Any process involved in the maintenance of an internal steady state of cadmium ions at the level of a cell.
6877	cellular cobalt ion homeostasis	P	Any process involved in the maintenance of an internal steady state of cobalt ions at the level of a cell.
6878	cellular copper ion homeostasis	P	Any process involved in the maintenance of an internal steady state of copper ions at the level of a cell.
6879	cellular iron ion homeostasis	P	Any process involved in the maintenance of an internal steady state of iron ions at the level of a cell.
6880	intracellular sequestering of iron ion	P	The process of binding or confining iron ions in an intracellular area such that they are separated from other components of a biological system.
6881	extracellular sequestering of iron ion	P	The process of binding or confining iron ions in an extracellular area such that they are separated from other components of a biological system.
6882	cellular zinc ion homeostasis	P	Any process involved in the maintenance of an internal steady state of zinc ions at the level of a cell.
6883	cellular sodium ion homeostasis	P	Any process involved in the maintenance of an internal steady state of sodium ions at the level of a cell.
6884	cell volume homeostasis	P	Any process involved in maintaining the steady state of a cell's volume. The cell's volume refers to the three-dimensional space occupied by a cell.
6885	regulation of pH	P	Any process involved in the maintenance of an internal equilibrium of hydrogen ions, thereby modulating the internal pH, within an organism or cell.
6886	intracellular protein transport	P	The directed movement of proteins in a cell, including the movement of proteins between specific compartments or structures within a cell, such as organelles of a eukaryotic cell.
6887	exocytosis	P	A process of secretion by a cell that results in the release of intracellular molecules (e.g. hormones, matrix proteins) contained within a membrane-bounded vesicle by fusion of the vesicle with the plasma membrane of a cell. This process begins with steps that prepare vesicles for fusion with the membrane (tethering and docking) and ends when vesicle fusion is complete. This is the process in which most molecules are secreted from eukaryotic cells.
6888	ER to Golgi vesicle-mediated transport	P	The directed movement of substances from the endoplasmic reticulum (ER) to the Golgi, mediated by COP II vesicles. Small COP II coated vesicles form from the ER and then fuse directly with the cis-Golgi. Larger structures are transported along microtubules to the cis-Golgi.
6890	retrograde vesicle-mediated transport, Golgi to ER	P	The directed movement of substances from the Golgi back to the endoplasmic reticulum, mediated by vesicles bearing specific protein coats such as COPI or COG.
6891	intra-Golgi vesicle-mediated transport	P	The directed movement of substances within the Golgi, mediated by small transport vesicles. These either fuse with the cis-Golgi or with each other to form the membrane stacks known as the cis-Golgi reticulum (network).
6892	post-Golgi vesicle-mediated transport	P	The directed movement of substances from the Golgi to other parts of the cell, including organelles and the plasma membrane, mediated by small transport vesicles.
6893	Golgi to plasma membrane transport	P	The directed movement of substances from the Golgi to the plasma membrane in transport vesicles that move from the trans-Golgi network to the plasma membrane, where they fuse and release their contents by exocytosis.
6895	Golgi to endosome transport	P	The directed movement of substances from the Golgi to early sorting endosomes. Clathrin vesicles transport substances from the trans-Golgi to endosomes.
6896	Golgi to vacuole transport	P	The directed movement of substances from the Golgi to the vacuole.
6897	endocytosis	P	A vesicle-mediated transport process in which cells take up external materials or membrane constituents by the invagination of a small region of the plasma membrane to form a new membrane-bounded vesicle.
6898	receptor-mediated endocytosis	P	An endocytosis process in which cell surface receptors ensure specificity of transport. A specific receptor on the cell surface binds tightly to the extracellular macromolecule (the ligand) that it recognizes; the plasma-membrane region containing the receptor-ligand complex then undergoes endocytosis, forming a transport vesicle containing the receptor-ligand complex and excluding most other plasma-membrane proteins. Receptor-mediated endocytosis generally occurs via clathrin-coated pits and vesicles.
6900	membrane budding	P	The evagination of a membrane, resulting in formation of a vesicle.
6901	vesicle coating	P	A protein coat is added to the vesicle to form the proper shape of the vesicle and to target the vesicle for transport to its destination.
6903	vesicle targeting	P	The process in which vesicles are directed to specific destination membranes. Targeting involves coordinated interactions among cytoskeletal elements (microtubules or actin filaments), motor proteins, molecules at the vesicle membrane and target membrane surfaces, and vesicle cargo.
6904	vesicle docking involved in exocytosis	P	The initial attachment of a vesicle membrane to a target membrane, mediated by proteins protruding from the membrane of the vesicle and the target membrane, that contributes to exocytosis.
6906	vesicle fusion	P	Fusion of the membrane of a transport vesicle with its target membrane.
6907	pinocytosis	P	An endocytosis process that results in the uptake of liquid material by cells from their external environment; literally 'cell drinking'. Liquid is enclosed in vesicles, called pinosomes, formed by invagination of the plasma membrane.
6909	phagocytosis	P	An endocytosis process that results in the engulfment of external particulate material by phagocytes. The particles are initially contained within phagocytic vacuoles (phagosomes), which then fuse with primary lysosomes to effect digestion of the particles.
6910	phagocytosis, recognition	P	The initial step in phagocytosis involving adhesion to bacteria, immune complexes and other particulate matter, or an apoptotic cell and based on recognition of factors such as bacterial cell wall components, opsonins like complement and antibody or protein receptors and lipids like phosphatidyl serine, and leading to intracellular signaling in the phagocytosing cell.
6911	phagocytosis, engulfment	P	The internalization of bacteria, immune complexes and other particulate matter or of an apoptotic cell by phagocytosis, including the membrane and cytoskeletal processes required, which involves one of three mechanisms: zippering of pseudopods around a target via repeated receptor-ligand interactions, sinking of the target directly into plasma membrane of the phagocytosing cell, or induced uptake via an enhanced membrane ruffling of the phagocytosing cell similar to macropinocytosis.
6913	nucleocytoplasmic transport	P	The directed movement of molecules between the nucleus and the cytoplasm.
6914	autophagy	P	The process in which cells digest parts of their own cytoplasm; allows for both recycling of macromolecular constituents under conditions of cellular stress and remodeling the intracellular structure for cell differentiation.
6915	apoptotic process	P	A programmed cell death process which begins when a cell receives an internal (e.g. DNA damage) or external signal (e.g. an extracellular death ligand), and proceeds through a series of biochemical events (signaling pathway phase) which trigger an execution phase. The execution phase is the last step of an apoptotic process, and is typically characterized by rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died.
6919	activation of cysteine-type endopeptidase activity involved in apoptotic process	P	Any process that initiates the activity of the inactive enzyme cysteine-type endopeptidase in the context of an apoptotic process.
6921	cellular component disassembly involved in execution phase of apoptosis	P	The breakdown of structures such as organelles, proteins, or other macromolecular structures during apoptosis.
6924	activation-induced cell death of T cells	P	A T cell apoptotic process that occurs towards the end of the expansion phase following the initial activation of mature T cells by antigen and is triggered by T cell receptor stimulation and signals transmitted via various surface-expressed members of the TNF receptor family such as Fas ligand, Fas, and TNF and the p55 and p75 TNF receptors.
6925	inflammatory cell apoptotic process	P	Any apoptotic process in an inflammatory cell, any cell participating in the inflammatory response to a foreign substance e.g. neutrophil, macrophage.
6928	movement of cell or subcellular component	P	The directed, self-propelled movement of a cell or subcellular component without the involvement of an external agent such as a transporter or a pore.
6929	substrate-dependent cell migration	P	The orderly movement of a cell from one site to another along a substrate such as the extracellular matrix; the migrating cell forms a protrusion that attaches to the substrate.
6930	substrate-dependent cell migration, cell extension	P	The formation of a cell surface protrusion, such as a lamellipodium or filopodium, at the leading edge of a migrating cell.
6931	substrate-dependent cell migration, cell attachment to substrate	P	The formation of adhesions that stabilize protrusions at the leading edge of a migrating cell; involves integrin activation, clustering, and the recruitment of structural and signaling components to nascent adhesions.
6932	substrate-dependent cell migration, cell contraction	P	The translocation of the cell body forward during cell migration, mediated by tractional force on its substrate and tension in the cortical cytoskeleton. Adhesions transmit propulsive forces and serve as traction points over which the cell moves.
6933	negative regulation of cell adhesion involved in substrate-bound cell migration	P	The disassembly of adhesions at the front and rear of a migrating cell. At the leading edge, adhesion disassembly accompanies the formation of new protrusions; at the cell rear, it promotes tail retraction.
6934	substrate-bound cell migration, adhesion receptor recycling	P	The directed movement of accumulated adhesion components such as integrins from the rear of a migrating cell toward the cell front, where they are available to form new protrusions and adhesions.
6935	chemotaxis	P	The directed movement of a motile cell or organism, or the directed growth of a cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis).
6936	muscle contraction	P	A process in which force is generated within muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis.
6937	regulation of muscle contraction	P	Any process that modulates the frequency, rate or extent of muscle contraction.
6939	smooth muscle contraction	P	A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. Smooth muscle differs from striated muscle in the much higher actin/myosin ratio, the absence of conspicuous sarcomeres and the ability to contract to a much smaller fraction of its resting length.
6940	regulation of smooth muscle contraction	P	Any process that modulates the frequency, rate or extent of smooth muscle contraction.
6941	striated muscle contraction	P	A process in which force is generated within striated muscle tissue, resulting in the shortening of the muscle. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. Striated muscle is a type of muscle in which the repeating units (sarcomeres) of the contractile myofibrils are arranged in registry throughout the cell, resulting in transverse or oblique striations observable at the level of the light microscope.
6942	regulation of striated muscle contraction	P	Any process that modulates the frequency, rate or extent of striated muscle contraction.
6948	induction by virus of host cell-cell fusion	P	The process of syncytia-forming cell-cell fusion, caused by a virus.
6949	syncytium formation	P	The formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane. Syncytia are normally derived from single cells that fuse or fail to complete cell division.
6950	response to stress	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).
6952	defense response	P	Reactions, triggered in response to the presence of a foreign body or the occurrence of an injury, which result in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack.
6953	acute-phase response	P	An acute inflammatory response that involves non-antibody proteins whose concentrations in the plasma increase in response to infection or injury of homeothermic animals.
6954	inflammatory response	P	The immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The process is characterized by local vasodilation, extravasation of plasma into intercellular spaces and accumulation of white blood cells and macrophages.
6955	immune response	P	Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat.
6956	complement activation	P	Any process involved in the activation of any of the steps of the complement cascade, which allows for the direct killing of microbes, the disposal of immune complexes, and the regulation of other immune processes; the initial steps of complement activation involve one of three pathways, the classical pathway, the alternative pathway, and the lectin pathway, all of which lead to the terminal complement pathway.
6957	complement activation, alternative pathway	P	Any process involved in the activation of any of the steps of the alternative pathway of the complement cascade which allows for the direct killing of microbes and the regulation of other immune processes.
6958	complement activation, classical pathway	P	Any process involved in the activation of any of the steps of the classical pathway of the complement cascade which allows for the direct killing of microbes, the disposal of immune complexes, and the regulation of other immune processes.
6959	humoral immune response	P	An immune response mediated through a body fluid.
6962	male-specific antibacterial humoral response	P	An immune response against bacteria, specific to males and mediated through a body fluid.
6963	positive regulation of antibacterial peptide biosynthetic process	P	Any process that activates or increases the frequency, rate, or extent of antibacterial peptide biosynthesis.
6964	positive regulation of biosynthetic process of antibacterial peptides active against Gram-negative bacteria	P	Any process that activates or increases the frequency, rate, or extent of biosynthesis of antibacterial peptides active against Gram-negative bacteria.
6965	positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria	P	Any process that activates or increases the frequency, rate, or extent of biosynthesis of antibacterial peptides active against Gram-positive bacteria.
6967	positive regulation of antifungal peptide biosynthetic process	P	Any process that activates or increases the frequency, rate, or extent of antifungal peptide biosynthesis.
6968	cellular defense response	P	A defense response that is mediated by cells.
6970	response to osmotic stress	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell.
6971	hypotonic response	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a hypotonic environment, i.e. an environment with a lower concentration of solutes than the organism or cell.
6972	hyperosmotic response	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a hyperosmotic environment, i.e. an environment with a higher concentration of solutes than the organism or cell.
6973	intracellular accumulation of glycerol	P	The accumulation of glycerol within a cell, for example by increased glycerol biosynthesis combined with decreased permeability of the cell membrane to glycerol, in response to the detection of a hyperosmotic environment.
6974	cellular response to DNA damage stimulus	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to its DNA from environmental insults or errors during metabolism.
6975	DNA damage induced protein phosphorylation	P	The widespread phosphorylation of various molecules, triggering many downstream processes, that occurs in response to the detection of DNA damage.
6977	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest	P	A cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage and resulting in the stopping or reduction in rate of the cell cycle.
6978	DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator	P	A cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, resulting in the induction of the transcription of p21 (also known as WAF1, CIP1 and SDI1) or any equivalent protein, in response to the detection of DNA damage.
6979	response to oxidative stress	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
6981	activation of SoxR protein	P	The conversion of the SoxR transcription factor to its active (oxidized) form.
6982	response to lipid hydroperoxide	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipid hydroperoxide stimulus. Lipid hydroperoxide is the highly reactive primary oxygenated products of polyunsaturated fatty acids.
6983	ER overload response	P	The series of molecular signals generated by the accumulation of normal or misfolded proteins in the endoplasmic reticulum and leading to activation of transcription by NF-kappaB.
6984	ER-nucleus signaling pathway	P	Any series of molecular signals that conveys information from the endoplasmic reticulum to the nucleus, usually resulting in a change in transcriptional regulation.
6985	positive regulation of NF-kappaB transcription factor activity by ER overload response	P	The conversion of inactive NF-kappaB to the active form, thereby allowing it to activate transcription of target genes, as a result of signaling from the endoplasmic reticulum.
6986	response to unfolded protein	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an unfolded protein stimulus.
6987	activation of signaling protein activity involved in unfolded protein response	P	The conversion of a specific protein, possessing protein kinase and endoribonuclease activities, to an active form as a result of signaling via the unfolded protein response.
6990	positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response	P	The activation of genes whose promoters contain a specific sequence elements such as the unfolded protein response element (UPRE; consensus CAGCGTG) or the ER stress-response element (ERSE; CCAAN(N)9CCACG), as a result of signaling via the unfolded protein response.
6991	response to sterol depletion	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating deprivation of sterols. Sterols are a group of steroids characterized by the presence of one or more hydroxyl groups and a hydrocarbon side-chain in the molecule.
6995	cellular response to nitrogen starvation	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of nitrogen.
6996	organelle organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an organelle within a cell. An organelle is an organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.
6997	nucleus organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nucleus.
6998	nuclear envelope organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear envelope.
6999	nuclear pore organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear pore.
7000	nucleolus organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nucleolus.
7004	telomere maintenance via telomerase	P	The maintenance of proper telomeric length by the addition of telomeric repeats by telomerase.
7005	mitochondrion organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a mitochondrion; includes mitochondrial morphogenesis and distribution, and replication of the mitochondrial genome as well as synthesis of new mitochondrial components.
7006	mitochondrial membrane organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a mitochondrial membrane, either of the lipid bilayer surrounding a mitochondrion.
7007	inner mitochondrial membrane organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the mitochondrial inner membrane.
7008	outer mitochondrial membrane organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the mitochondrial outer membrane.
7009	plasma membrane organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the plasma membrane.
7010	cytoskeleton organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures.
7014	actin ubiquitination	P	The modification of actin by addition of ubiquitin groups.
7015	actin filament organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments. Includes processes that control the spatial distribution of actin filaments, such as organizing filaments into meshworks, bundles, or other structures, as by cross-linking.
7016	cytoskeletal anchoring at plasma membrane	P	A cytoskeleton organization process that directly or indirectly links cytoskeletal filaments to the plasma membrane.
7017	microtubule-based process	P	Any cellular process that depends upon or alters the microtubule cytoskeleton, that part of the cytoskeleton comprising microtubules and their associated proteins.
7018	microtubule-based movement	P	A microtubule-based process that results in the movement of organelles, other microtubules, or other cellular components. Examples include motor-driven movement along microtubules and movement driven by polymerization or depolymerization of microtubules.
7019	microtubule depolymerization	P	The removal of tubulin heterodimers from one or both ends of a microtubule.
7020	microtubule nucleation	P	The process in which tubulin alpha-beta heterodimers begin aggregation to form an oligomeric tubulin structure (a microtubule seed). Microtubule nucleation is the initiating step in the formation of a microtubule in the absence of any existing microtubules ('de novo' microtubule formation).
7021	tubulin complex assembly	P	The aggregation and bonding together of alpha- and beta-tubulin to form a tubulin heterodimer.
7023	post-chaperonin tubulin folding pathway	P	Completion of folding of alpha- and beta-tubulin; takes place subsequent to chaperonin-mediated partial folding; mediated by a complex of folding cofactors.
7026	negative regulation of microtubule depolymerization	P	Any process that stops, prevents, or reduces the frequency, rate or extent of microtubule depolymerization; prevention of depolymerization of a microtubule can result from binding by 'capping' at the plus end (e.g. by interaction with another cellular protein of structure) or by exposing microtubules to a stabilizing drug such as taxol.
7027	negative regulation of axonemal microtubule depolymerization	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the depolymerization of the specialized microtubules of the axoneme.
7028	cytoplasm organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the cytoplasm. The cytoplasm is all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
7029	endoplasmic reticulum organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the endoplasmic reticulum.
7030	Golgi organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the Golgi apparatus.
7031	peroxisome organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a peroxisome. A peroxisome is a small, membrane-bounded organelle that uses dioxygen (O2) to oxidize organic molecules.
7032	endosome organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of endosomes.
7033	vacuole organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a vacuole.
7034	vacuolar transport	P	The directed movement of substances into, out of or within a vacuole.
7035	vacuolar acidification	P	Any process that reduces the pH of the vacuole, measured by the concentration of the hydrogen ion.
7036	vacuolar calcium ion homeostasis	P	Any process involved in the maintenance of an internal steady state of calcium ions in the vacuole or between a vacuole and its surroundings.
7037	vacuolar phosphate transport	P	The directed movement of phosphates into, out of or within a vacuole.
7038	endocytosed protein transport to vacuole	P	The directed movement of proteins imported into a cell by endocytosis to the vacuole.
7039	protein catabolic process in the vacuole	P	The chemical reactions and pathways resulting in the breakdown of a protein in the vacuole, usually by the action of vacuolar proteases.
7040	lysosome organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lysosome. A lysosome is a cytoplasmic, membrane-bounded organelle that is found in most animal cells and that contains a variety of hydrolases.
7041	lysosomal transport	P	The directed movement of substances into, out of or within a lysosome.
7042	lysosomal lumen acidification	P	Any process that reduces the pH of the lysosomal lumen, measured by the concentration of the hydrogen ion.
7043	cell-cell junction assembly	P	The aggregation, arrangement and bonding together of a set of components to form a junction between cells.
7044	cell-substrate junction assembly	P	The aggregation, arrangement and bonding together of a set of components to form a junction between a cell and its substrate.
7045	cell-substrate adherens junction assembly	P	The aggregation, arrangement, and bonding together of a set of components to form a cell-substrate adherens junction.
7049	cell cycle	P	The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division.
7050	cell cycle arrest	P	A regulatory process that halts progression through the cell cycle during one of the normal phases (G1, S, G2, M).
7051	spindle organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the spindle, the array of microtubules and associated molecules that forms between opposite poles of a eukaryotic cell during DNA segregation and serves to move the duplicated chromosomes apart.
7052	mitotic spindle organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the microtubule spindle during a mitotic cell cycle.
7053	spindle assembly involved in male meiosis	P	The aggregation, arrangement and bonding together of a set of components to form the spindle during a meiotic cell cycle in males. An example of this is found in Drosophila melanogaster.
7054	spindle assembly involved in male meiosis I	P	The formation of the spindle during meiosis I of a meiotic cell cycle in males. An example of this is found in Drosophila melanogaster.
7055	spindle assembly involved in male meiosis II	P	The formation of the spindle during meiosis II of a meiotic cell cycle in males. An example of this is found in Drosophila melanogaster.
7056	spindle assembly involved in female meiosis	P	The aggregation, arrangement and bonding together of a set of components to form the spindle during a meiotic cell cycle in females. An example of this is found in Drosophila melanogaster.
7057	spindle assembly involved in female meiosis I	P	The aggregation, arrangement and bonding together of a set of components to form the spindle during meiosis I of a meiotic cell cycle in females. An example of this is found in Drosophila melanogaster.
7058	spindle assembly involved in female meiosis II	P	The aggregation, arrangement and bonding together of a set of components to form the spindle during meiosis II of a meiotic cell cycle in females. An example of this is found in Drosophila melanogaster.
7059	chromosome segregation	P	The process in which genetic material, in the form of chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets. In eukaryotes, chromosome segregation begins with the condensation of chromosomes, includes chromosome separation, and ends when chromosomes have completed movement to the spindle poles.
7060	male meiosis chromosome segregation	P	The cell cycle process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets during the meiotic cell cycle in a male.
7062	sister chromatid cohesion	P	The cell cycle process in which the sister chromatids of a replicated chromosome become tethered to each other.
7063	regulation of sister chromatid cohesion	P	Any process that modulates the frequency, rate or extent of sister chromatid cohesion.
7064	mitotic sister chromatid cohesion	P	The cell cycle process in which the sister chromatids of a replicated chromosome are joined along the entire length of the chromosome, from their formation in S phase through metaphase during a mitotic cell cycle. This cohesion cycle is critical for high fidelity chromosome transmission.
7065	male meiosis sister chromatid cohesion	P	The joining of the sister chromatids of a replicated chromosome along the entire length of the chromosome that occurs during meiosis in a male.
7066	female meiosis sister chromatid cohesion	P	The joining of the sister chromatids of a replicated chromosome along the entire length of the chromosome that occurs during meiosis in a female.
7067	mitotic nuclear division	P	A mitotic cell cycle process comprising the steps by which the nucleus of a eukaryotic cell divides; the process involves condensation of chromosomal DNA into a highly compacted form. Canonically, mitosis produces two daughter nuclei whose chromosome complement is identical to that of the mother cell.
7068	negative regulation of transcription during mitotic cell cycle	P	Any process that stops, prevents, or reduces the frequency, rate or extent of transcription that occurs during the mitotic cell cycle.
7069	negative regulation of transcription from RNA polymerase I promoter during mitotic cell cycle	P	Any process that stops, prevents, or reduces the frequency, rate or extent of transcription from an RNA polymerase I promoter that occurs during the mitotic cell cycle.
7070	negative regulation of transcription from RNA polymerase II promoter during mitotic cell cycle	P	Any process that stops, prevents, or reduces the frequency, rate or extent of transcription from an RNA polymerase II promoter that occurs during the mitotic cell cycle.
7071	negative regulation of transcription from RNA polymerase III promoter during mitotic cell cycle	P	Any process that stops, prevents, or reduces the frequency, rate or extent of transcription from an RNA polymerase III promoter that occurs during the mitotic cell cycle.
7072	positive regulation of transcription involved in exit from mitosis	P	Any process that increases the frequency, rate or extent of transcription as the cell leaves M phase. M phase is the part of the mitotic cell cycle during which mitosis and cytokinesis take place.
7073	positive regulation of transcription involved in exit from mitosis, from RNA polymerase I promoter	P	Any process that increases the frequency, rate or extent of transcription from an RNA polymerase I promoter as the cell leaves M phase. M phase is the part of the mitotic cell cycle during which mitosis and cytokinesis take place.
7074	positive regulation of transcription involved in exit from mitosis, from RNA polymerase II promoter	P	Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as the cell leaves M phase. M phase is the part of the mitotic cell cycle during which mitosis and cytokinesis take place.
7075	positive regulation of transcription involved in exit from mitosis, from RNA polymerase III promoter	P	Any process that increases the frequency, rate or extent of transcription from an RNA polymerase III promoter as the cell leaves M phase. M phase is the part of the mitotic cell cycle during which mitosis and cytokinesis take place.
7076	mitotic chromosome condensation	P	The cell cycle process in which chromatin structure is compacted prior to and during mitosis in eukaryotic cells.
7077	mitotic nuclear envelope disassembly	P	The cell cycle process in which the controlled breakdown of the nuclear envelope during mitotic cell division occurs.
7078	lamin depolymerization	P	The cell cycle process in which lamin is depolymerized.
7079	mitotic chromosome movement towards spindle pole	P	The cell cycle process in which the directed movement of chromosomes from the center of the spindle towards the spindle poles occurs. This mediates by the shortening of microtubules attached to the chromosomes, during mitosis.
7080	mitotic metaphase plate congression	P	The cell cycle process in which chromosomes are aligned at the metaphase plate, a plane halfway between the poles of the mitotic spindle, during mitosis.
7083	mitotic chromosome decondensation	P	The cell cycle process in which chromosome structure is altered from the condensed form taken on during mitosis to the relaxed disperse form held in resting cells.
7084	mitotic nuclear envelope reassembly	P	The cell cycle process that results in reformation of the nuclear envelope during mitotic cell division.
7086	vesicle fusion with nuclear membrane involved in mitotic nuclear envelope reassembly	P	The cell cycle process that results in the joining of the lipid bilayer membrane around a vesicle with the lipid bilayer membrane around the nucleus, and contributes to mitotic nuclear envelope reassembly.
7087	mitotic nuclear pore complex reassembly	P	The cell cycle process in which nuclear pore complexes reform during mitotic cell division.
7088	regulation of mitotic nuclear division	P	Any process that modulates the frequency, rate or extent of mitosis.
7089	traversing start control point of mitotic cell cycle	P	A cell cycle process by which a cell commits to entering S phase via a positive feedback mechanism between the regulation of transcription and G1 CDK activity.
7091	metaphase/anaphase transition of mitotic cell cycle	P	The cell cycle process in which a cell progresses from metaphase to anaphase during mitosis, triggered by the activation of the anaphase promoting complex by Cdc20/Sleepy homolog which results in the degradation of Securin.
7093	mitotic cell cycle checkpoint	P	A cell cycle checkpoint that ensures accurate chromosome replication and segregation by preventing progression through a mitotic cell cycle until conditions are suitable for the cell to proceed to the next stage.
7094	mitotic spindle assembly checkpoint	P	A cell cycle checkpoint that delays the metaphase/anaphase transition of a mitotic nuclear division until the spindle is correctly assembled and chromosomes are attached to the spindle.
7095	mitotic G2 DNA damage checkpoint	P	A mitotic cell cycle checkpoint that detects and negatively regulates progression through the G2/M transition of the cell cycle in response to DNA damage.
7096	regulation of exit from mitosis	P	Any process involved in the progression from anaphase/telophase to G1 that is associated with a conversion from high to low mitotic CDK activity.
7097	nuclear migration	P	The directed movement of the nucleus.
7098	centrosome cycle	P	The cell cycle process in which centrosome duplication and separation takes place. The centrosome cycle can operate with a considerable degree of independence from other processes of the cell cycle.
7099	centriole replication	P	The cell cycle process in which a daughter centriole is formed perpendicular to an existing centriole. An immature centriole contains a ninefold radially symmetric array of single microtubules; mature centrioles consist of a radial array of nine microtubule triplets, doublets, or singlets depending upon the species and cell type. Duplicated centrioles also become the ciliary basal body in cells that form cilia during G0.
7100	mitotic centrosome separation	P	Separation of duplicated centrosome components at the beginning of mitosis. The centriole pair within each centrosome becomes part of a separate microtubule organizing center that nucleates a radial array of microtubules called an aster. The two asters move to opposite sides of the nucleus to form the two poles of the mitotic spindle.
7101	male meiosis centrosome cycle	P	Centrosome duplication and separation in the context of a meiotic cell cycle in a male organism.
7105	cytokinesis, site selection	P	The process of marking the place where cytokinesis will occur.
7107	membrane addition at site of cytokinesis	P	Any process involved in the net addition of membrane at the site of cytokinesis; includes vesicle recruitment and fusion, local lipid synthesis and insertion.
7110	meiosis I cytokinesis	P	A cell cycle process that results in the division of the cytoplasm of a cell after meiosis I, resulting in the separation of the original cell into two daughter cells.
7111	meiosis II cytokinesis	P	A cell cycle process that results in the division of the cytoplasm of a cell after meiosis II, resulting in the separation of the original cell into two daughter cells.
7112	male meiosis cytokinesis	P	A cell cycle process that occurs as part of the male meiotic cell cycle and results in the division of the cytoplasm of a cell to produce two daughter cells.
7113	endomitotic cell cycle	P	A mitotic cell cycle in which chromosomes are replicated and sister chromatids separate, but spindle formation, nuclear membrane breakdown and nuclear division do not occur, resulting in an increased number of chromosomes in the cell.
7114	cell budding	P	A form of asexual reproduction, occurring in certain bacteria and fungi (e.g. yeasts) and some primitive animals in which an individual arises from a daughter cell formed by pinching off a part of the parent cell. The budlike outgrowths so formed may sometimes remain attached to the parent cell.
7116	regulation of cell budding	P	Any process that modulates the frequency, rate or extent of the formation and growth of cell buds.
7117	budding cell bud growth	P	The process in which the bud portion of a cell that reproduces by budding irreversibly increases in size over time by accretion and biosynthetic production of matter similar to that already present.
7118	budding cell apical bud growth	P	Growth at the tip of a bud, in a cell that reproduces by budding.
7119	budding cell isotropic bud growth	P	Unlocalized bud growth such that the entire surface of the bud expands evenly, in a cell that reproduces by budding.
7120	axial cellular bud site selection	P	The process of defining the next site of bud emergence adjacent to the last site of bud emergence on a budding cell.
7121	bipolar cellular bud site selection	P	The process of defining subsequent sites of bud emergence such that budding takes place at alternating poles of a budding cell.
7124	pseudohyphal growth	P	A pattern of cell growth that occurs in conditions of nitrogen limitation and abundant fermentable carbon source. Cells become elongated, switch to a unipolar budding pattern, remain physically attached to each other, and invade the growth substrate.
7126	meiotic nuclear division	P	One of the two nuclear divisions that occur as part of the meiotic cell cycle.
7127	meiosis I	P	The first meiotic nuclear division in which homologous chromosomes are paired and segregated from each other, producing two haploid daughter nuclei.
7128	meiotic prophase I	P	The cell cycle phase which is the first stage of meiosis I and during which chromosomes condense and the two daughter centrioles and their asters migrate toward the poles of the cell.
7129	synapsis	P	The meiotic cell cycle process where side by side pairing and physical juxtaposition of homologous chromosomes is created during meiotic prophase. Synapsis begins when the chromosome arms begin to pair from the clustered telomeres and ends when synaptonemal complex or linear element assembly is complete.
7130	synaptonemal complex assembly	P	The cell cycle process in which the synaptonemal complex is formed. This is a structure that holds paired chromosomes together during prophase I of meiosis and that promotes genetic recombination.
7131	reciprocal meiotic recombination	P	The cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate. This results in the equal exchange of genetic material between non-sister chromatids in a pair of homologous chromosomes. These reciprocal recombinant products ensure the proper segregation of homologous chromosomes during meiosis I and create genetic diversity.
7132	meiotic metaphase I	P	The cell cycle phase, following prophase I, during which chromosomes become aligned on the equatorial plate of the cell as part of meiosis I.
7133	meiotic anaphase I	P	The cell cycle phase during which chromosomes separate and migrate towards the poles of the spindle the as part of meiosis I.
7134	meiotic telophase I	P	The cell cycle phase which follows anaphase I of meiosis and during which the chromosomes arrive at the poles of the cell and the division of the cytoplasm starts.
7135	meiosis II	P	The second nuclear division of meiosis, in which the two chromatids in each chromosome are separated, resulting in four daughter nuclei from the two nuclei produced in meiosis II.
7136	meiotic prophase II	P	The cell cycle phase which is the first stage of meiosis II and during which chromosomes condense and the two daughter centrioles and their asters migrate toward the poles of the cell.
7137	meiotic metaphase II	P	The cell cycle phase, following prophase II, during which chromosomes become aligned on the equatorial plate of the cell as part of meiosis II.
7138	meiotic anaphase II	P	The cell cycle phase during which chromosomes separate and migrate towards the poles of the spindle the as part of meiosis II.
7139	meiotic telophase II	P	The cell cycle phase which follows anaphase II of meiosis and during which the chromosomes arrive at the poles of the cell and the division of the cytoplasm starts.
7140	male meiosis	P	A cell cycle process by which the cell nucleus divides as part of a meiotic cell cycle in the male germline.
7141	male meiosis I	P	A cell cycle process comprising the steps by which a cell progresses through male meiosis I, the first meiotic division in the male germline.
7142	male meiosis II	P	A cell cycle process comprising the steps by which a cell progresses through male meiosis II, the second meiotic division in the male germline.
7143	female meiotic division	P	A cell cycle process by which the cell nucleus divides as part of a meiotic cell cycle in the female germline.
7144	female meiosis I	P	The cell cycle process in which the first meiotic division occurs in the female germline.
7146	meiotic recombination nodule assembly	P	During meiosis, the aggregation, arrangement and bonding together of strand exchange proteins (recombinases) to form small, electron dense structures in association with meiotic chromosomes.
7147	female meiosis II	P	The cell cycle process in which the second meiotic division occurs in the female germline.
7154	cell communication	P	Any process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.
7155	cell adhesion	P	The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules.
7156	homophilic cell adhesion via plasma membrane adhesion molecules	P	The attachment of a plasma membrane adhesion molecule in one cell to an identical molecule in an adjacent cell.
7157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules	P	The attachment of an adhesion molecule in one cell to a nonidentical adhesion molecule in an adjacent cell.
7158	neuron cell-cell adhesion	P	The attachment of a neuron to another cell via adhesion molecules.
7159	leukocyte cell-cell adhesion	P	The attachment of a leukocyte to another cell via adhesion molecules.
7160	cell-matrix adhesion	P	The binding of a cell to the extracellular matrix via adhesion molecules.
7161	calcium-independent cell-matrix adhesion	P	The binding of a cell to the extracellular matrix via adhesion molecules that do not require the presence of calcium for the interaction.
7162	negative regulation of cell adhesion	P	Any process that stops, prevents, or reduces the frequency, rate or extent of cell adhesion.
7163	establishment or maintenance of cell polarity	P	Any cellular process that results in the specification, formation or maintenance of anisotropic intracellular organization or cell growth patterns.
7164	establishment of tissue polarity	P	Coordinated organization of groups of cells in a tissue, such that they all orient to similar coordinates.
7165	signal transduction	P	The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell.
7166	cell surface receptor signaling pathway	P	A series of molecular signals initiated by activation of a receptor on the surface of a cell. The pathway begins with binding of an extracellular ligand to a cell surface receptor, or for receptors that signal in the absence of a ligand, by ligand-withdrawal or the activity of a constitutively active receptor. The pathway ends with regulation of a downstream cellular process, e.g. transcription.
7167	enzyme linked receptor protein signaling pathway	P	Any series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell, where the receptor possesses catalytic activity or is closely associated with an enzyme such as a protein kinase, and ending with regulation of a downstream cellular process, e.g. transcription.
7168	receptor guanylyl cyclase signaling pathway	P	A series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell where the receptor possesses guanylyl cyclase activity, and ending with regulation of a downstream cellular process, e.g. transcription.
7169	transmembrane receptor protein tyrosine kinase signaling pathway	P	A series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell where the receptor possesses tyrosine kinase activity, and ending with regulation of a downstream cellular process, e.g. transcription.
7171	activation of transmembrane receptor protein tyrosine kinase activity	P	Any process that initiates the activity of the inactive transmembrane receptor protein tyrosine kinase activity.
7172	signal complex assembly	P	The aggregation, arrangement and bonding together of a set of components to form a complex capable of relaying a signal within a cell.
7173	epidermal growth factor receptor signaling pathway	P	A series of molecular signals initiated by binding of a ligand to the tyrosine kinase receptor EGFR (ERBB1) on the surface of a cell. The pathway ends with regulation of a downstream cellular process, e.g. transcription.
7174	epidermal growth factor catabolic process	P	The chemical reactions and pathways resulting in the breakdown of epidermal growth factor (EGF), following internalization of the receptor-bound ligand into the signal-receiving cell. Full breakdown of epidermal growth factor results in a ligand that is unable to bind and activate its receptor.
7175	negative regulation of epidermal growth factor-activated receptor activity	P	Any process that stops, prevents, or reduces the frequency, rate or extent of EGF-activated receptor activity.
7176	regulation of epidermal growth factor-activated receptor activity	P	Any process that modulates the frequency, rate or extent of EGF-activated receptor activity.
7178	transmembrane receptor protein serine/threonine kinase signaling pathway	P	A series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell where the receptor possesses serine/threonine kinase activity, and ending with regulation of a downstream cellular process, e.g. transcription.
7179	transforming growth factor beta receptor signaling pathway	P	A series of molecular signals initiated by the binding of an extracellular ligand to a transforming growth factor beta receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.
7181	transforming growth factor beta receptor complex assembly	P	The aggregation, arrangement and bonding together of a ligand-bound type II transforming growth factor beta (TGF-beta) receptor dimer with a type I TGF-beta receptor dimer, following ligand binding, to form a heterotetrameric TGF-beta receptor complex.
7182	common-partner SMAD protein phosphorylation	P	The process of introducing a phosphate group on to a common-partner SMAD protein. A common partner SMAD protein binds to pathway-restricted SMAD proteins forming a complex that translocates to the nucleus.
7183	SMAD protein complex assembly	P	The aggregation, arrangement and bonding together of a set of components to form a protein complex that contains SMAD proteins.
7184	SMAD protein import into nucleus	P	The directed movement of a SMAD proteins from the cytoplasm into the nucleus. Pathway-restricted SMAD proteins and common-partner SMAD proteins are involved in the transforming growth factor beta receptor signaling pathways.
7185	transmembrane receptor protein tyrosine phosphatase signaling pathway	P	A series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell where the receptor possesses protein tyrosine phosphatase activity, and ending with regulation of a downstream cellular process, e.g. transcription.
7186	G-protein coupled receptor signaling pathway	P	A series of molecular signals that proceeds with an activated receptor promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-ligand interaction, or for basal GPCR signaling the pathway begins with the receptor activating its G protein in the absence of an agonist, and ends with regulation of a downstream cellular process, e.g. transcription. The pathway can start from the plasma membrane, Golgi or nuclear membrane (PMID:24568158 and PMID:16902576).
7187	G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger	P	The series of molecular signals generated as a consequence of a G-protein coupled receptor binding to its physiological ligand, where the pathway proceeds with activation or inhibition of a nucleotide cyclase activity and a subsequent change in the concentration of a cyclic nucleotide.
7188	adenylate cyclase-modulating G-protein coupled receptor signaling pathway	P	The series of molecular signals generated as a consequence of a G-protein coupled receptor binding to its physiological ligand, where the pathway proceeds through activation or inhibition of adenylyl cyclase activity and a subsequent change in the concentration of cyclic AMP (cAMP).
7189	adenylate cyclase-activating G-protein coupled receptor signaling pathway	P	The series of molecular signals generated as a consequence of a G-protein coupled receptor binding to its physiological ligand, where the pathway proceeds through activation of adenylyl cyclase activity and a subsequent increase in the concentration of cyclic AMP (cAMP).
7190	activation of adenylate cyclase activity	P	Any process that initiates the activity of the inactive enzyme adenylate cyclase.
7191	adenylate cyclase-activating dopamine receptor signaling pathway	P	The series of molecular signals generated as a consequence of a dopamine receptor binding to its physiological ligand, where the pathway proceeds with activation of adenylyl cyclase and a subsequent increase in the concentration of cyclic AMP (cAMP).
7192	adenylate cyclase-activating serotonin receptor signaling pathway	P	The series of molecular signals generated as a consequence of a serotonin receptor binding to its physiological ligand, where the pathway proceeds with activation of adenylyl cyclase and a subsequent increase in the concentration of cyclic AMP (cAMP).
7193	adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway	P	The series of molecular signals generated as a consequence of a G-protein coupled receptor binding to its physiological ligand, where the pathway proceeds through inhibition of adenylyl cyclase activity and a subsequent decrease in the concentration of cyclic AMP (cAMP).
7194	negative regulation of adenylate cyclase activity	P	Any process that stops, prevents, or reduces the frequency, rate or extent of adenylate cyclase activity.
7195	adenylate cyclase-inhibiting dopamine receptor signaling pathway	P	The series of molecular signals generated as a consequence of a dopamine receptor binding to its physiological ligand, where the pathway proceeds with inhibition of adenylyl cyclase and a subsequent decrease in the concentration of cyclic AMP (cAMP).
7196	adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway	P	The series of molecular signals generated as a consequence of a G-protein coupled glutamate receptor binding to its physiological ligand, where the pathway proceeds with inhibition of adenylyl cyclase and a subsequent decrease in the concentration of cyclic AMP (cAMP).
7197	adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway	P	The series of molecular signals generated as a consequence of a G-protein coupled acetylcholine receptor binding to its physiological ligand, where the pathway proceeds with inhibition of adenylyl cyclase and a subsequent decrease in the concentration of cyclic AMP (cAMP).
7198	adenylate cyclase-inhibiting serotonin receptor signaling pathway	P	The series of molecular signals generated as a consequence of a serotonin receptor binding to its physiological ligand, where the pathway proceeds with inhibition of adenylyl cyclase and a subsequent decrease in the concentration of cyclic AMP (cAMP).
7199	G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger	P	The series of molecular signals generated as a consequence of a G-protein coupled receptor binding to its physiological ligand, followed by activation of guanylyl cyclase (GC) activity and a subsequent increase in the concentration of cyclic GMP (cGMP).
7200	phospholipase C-activating G-protein coupled receptor signaling pathway	P	The series of molecular signals generated as a consequence of a G-protein coupled receptor binding to its physiological ligand, where the pathway proceeds with activation of phospholipase C (PLC) and a subsequent increase in the concentration of inositol trisphosphate (IP3) and diacylglycerol (DAG).
7202	activation of phospholipase C activity	P	The initiation of the activity of the inactive enzyme phospolipase C as the result of a series of molecular signals generated as a consequence of a G-protein coupled receptor binding to its physiological ligand.
7204	positive regulation of cytosolic calcium ion concentration	P	Any process that increases the concentration of calcium ions in the cytosol.
7205	protein kinase C-activating G-protein coupled receptor signaling pathway	P	The series of molecular signals generated as a consequence of a G-protein coupled receptor binding to its physiological ligand, where the pathway proceeds with activation of protein kinase C (PKC). PKC is activated by second messengers including diacylglycerol (DAG).
7206	phospholipase C-activating G-protein coupled glutamate receptor signaling pathway	P	The series of molecular signals generated as a consequence of a G-protein coupled glutamate receptor binding to its physiological ligand, where the pathway proceeds with activation of phospholipase C (PLC) and a subsequent release of inositol trisphosphate (IP3) and diacylglycerol (DAG).
7207	phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway	P	The series of molecular signals generated as a consequence of a G-protein coupled acetylcholine receptor binding to its physiological ligand, where the pathway proceeds with activation of phospholipase C (PLC) and a subsequent release of inositol trisphosphate (IP3) and diacylglycerol (DAG).
7208	phospholipase C-activating serotonin receptor signaling pathway	P	The series of molecular signals generated as a consequence of a serotonin receptor binding to its physiological ligand, where the pathway proceeds with activation of phospholipase C (PLC) and a subsequent release of inositol trisphosphate (IP3) and diacylglycerol (DAG).
7209	phospholipase C-activating tachykinin receptor signaling pathway	P	The series of molecular signals generated as a consequence of a tachykinin receptor binding to its physiological ligand, where the pathway proceeds with activation of phospholipase C (PLC) and a subsequent release of inositol trisphosphate (IP3) and diacylglycerol (DAG).
7210	serotonin receptor signaling pathway	P	The series of molecular signals generated as a consequence of a serotonin receptor binding to one of its physiological ligands.
7211	octopamine or tyramine signaling pathway	P	The series of molecular signals generated as a consequence of octopamine or tyramine binding to a cell surface receptor. Octopamine and tyramine are decarboxylation products of tyrosine, and are the invertebrate counterparts of the vertebrate adrenergic transmitters.
7212	dopamine receptor signaling pathway	P	The series of molecular signals generated as a consequence of a dopamine receptor binding to one of its physiological ligands.
7213	G-protein coupled acetylcholine receptor signaling pathway	P	Any series of molecular signals initiated by an acetylcholine receptor on the surface of the target cell binding to one of its physiological ligands, and proceeding with the activated receptor promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-ligand interaction and ends with regulation of a downstream cellular process, e.g. transcription.
7214	gamma-aminobutyric acid signaling pathway	P	The series of molecular signals generated by the binding of gamma-aminobutyric acid (GABA, 4-aminobutyrate), an amino acid which acts as a neurotransmitter in some organisms, to a cell surface receptor.
7215	glutamate receptor signaling pathway	P	A series of molecular signals initiated by the binding of glutamate to a glutamate receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.
7216	G-protein coupled glutamate receptor signaling pathway	P	A series of molecular signals initiated by glutamate binding to a glutamate receptor on the surface of the target cell, and proceeding with the activated receptor promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. Ends with regulation of a downstream cellular process, e.g. transcription.
7217	tachykinin receptor signaling pathway	P	The series of molecular signals generated as a consequence of a tachykinin, i.e. a short peptide with the terminal sequence (Phe-X-Gly-Leu-Met-NH2), binding to a cell surface receptor.
7218	neuropeptide signaling pathway	P	The series of molecular signals generated as a consequence of a peptide neurotransmitter binding to a cell surface receptor.
7219	Notch signaling pathway	P	A series of molecular signals initiated by the binding of an extracellular ligand to the receptor Notch on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.
7220	Notch receptor processing	P	The series of successive proteolytic cleavages of the Notch protein, which result in an active form of the receptor.
7221	positive regulation of transcription of Notch receptor target	P	The activation of transcription of specific genes as a result of Notch signaling, mediated by the Notch intracellular domain.
7223	Wnt signaling pathway, calcium modulating pathway	P	The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors leads to an increase in intracellular calcium and activation of protein kinase C (PKC).
7224	smoothened signaling pathway	P	A series of molecular signals generated as a consequence of activation of the transmembrane protein Smoothened.
7225	patched ligand maturation	P	The posttranslational modification of members of the Hedgehog family of signaling proteins in order for Hedgehog to exert its biological activity. These modifications include cleavage of its signal sequence, autocatalytic protein cleavage and the attachment of sterol groups.
7227	signal transduction downstream of smoothened	P	The series of molecular signals that are initiated by the transmembrane protein Smoothened. In the presence of a Hedgehog signaling molecule, the Patched protein no longer inhibits the activity of Smoothened, and Smoothened signals via the Hedgehog signaling complex to activate downstream components of the Hedgehog signaling pathway.
7228	positive regulation of hh target transcription factor activity	P	Any process that increases the activity of a transcription factor that activates transcription of Hedgehog-target genes in response to Smoothened signaling. In Drosophila, Cubitus interruptus (Ci) is the only identified transcription factor so far in the Hedgehog signaling pathway. In vertebrates, members of the Gli protein family are activated in this way. Activation of the Gli/Ci transcription factor is distinct from its stabilization, when proteolytic cleavage is inhibited.
7229	integrin-mediated signaling pathway	P	A series of molecular signals initiated by the binding of extracellular ligand to an integrin on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.
7231	osmosensory signaling pathway	P	The series of molecular signals initiated in response to osmotic change.
7232	osmosensory signaling pathway via Sho1 osmosensor	P	A series of molecular signals generated in response to osmotic change, as mediated through a Sho1 osmosensor system.
7234	osmosensory signaling via phosphorelay pathway	P	A series of molecular signals generated in response to osmotic change, as mediated through a phosphorelay system.
7249	I-kappaB kinase/NF-kappaB signaling	P	The process in which a signal is passed on to downstream components within the cell through the I-kappaB-kinase (IKK)-dependent activation of NF-kappaB. The cascade begins with activation of a trimeric IKK complex (consisting of catalytic kinase subunits IKKalpha and/or IKKbeta, and the regulatory scaffold protein NEMO) and ends with the regulation of transcription of target genes by NF-kappaB. In a resting state, NF-kappaB dimers are bound to I-kappaB proteins, sequestering NF-kappaB in the cytoplasm. Phosphorylation of I-kappaB targets I-kappaB for ubiquitination and proteasomal degradation, thus releasing the NF-kappaB dimers, which can translocate to the nucleus to bind DNA and regulate transcription.
7250	activation of NF-kappaB-inducing kinase activity	P	The stimulation of the activity of NF-kappaB-inducing kinase through phosphorylation at specific residues.
7252	I-kappaB phosphorylation	P	The process of introducing a phosphate group into an inhibitor of kappa B (I-kappaB) protein. Phosphorylation of I-kappaB targets I-kappaB for ubiquitination and proteasomal degradation, thus releasing bound NF-kappaB dimers, which can translocate to the nucleus to bind DNA and regulate transcription.
7253	cytoplasmic sequestering of NF-kappaB	P	The selective interaction of the transcription factor NF-kappaB with specific molecules in the cytoplasm, thereby inhibiting its translocation into the nucleus.
7254	JNK cascade	P	An intracellular protein kinase cascade containing at least a JNK (a MAPK), a JNKK (a MAPKK) and a JUN3K (a MAP3K). The cascade can also contain two additional tiers: the upstream MAP4K and the downstream MAP Kinase-activated kinase (MAPKAPK). The kinases in each tier phosphorylate and activate the kinases in the downstream tier to transmit a signal within a cell.
7256	activation of JNKK activity	P	The initiation of the activity of the inactive enzyme JUN kinase kinase (JNKK) activity. JNKKs are involved in a signaling pathway that is primarily activated by cytokines and exposure to environmental stress.
7257	activation of JUN kinase activity	P	The initiation of the activity of the inactive enzyme JUN kinase (JNK).
7258	JUN phosphorylation	P	The process of introducing a phosphate group into a JUN protein.
7259	JAK-STAT cascade	P	Any process in which STAT proteins (Signal Transducers and Activators of Transcription) and JAK (Janus Activated Kinase) proteins convey a signal to trigger a change in the activity or state of a cell. The JAK-STAT cascade begins with activation of STAT proteins by members of the JAK family of tyrosine kinases, proceeds through dimerization and subsequent nuclear translocation of STAT proteins, and ends with regulation of target gene expression by STAT proteins.
7260	tyrosine phosphorylation of STAT protein	P	The process of introducing a phosphate group to a tyrosine residue of a STAT (Signal Transducer and Activator of Transcription) protein.
7262	STAT protein import into nucleus	P	The directed movement of dimerized STAT (Signal Transducers and Activators of Transcription) proteins into the nucleus following activation by members of the janus activated kinase (JAK) family of tyrosine kinases.
7263	nitric oxide mediated signal transduction	P	Any intracellular signal transduction in which the signal is passed on within the cell via nitric oxide (NO). Includes synthesis of nitric oxide, receptors/sensors for nitric oxide (such as soluble guanylyl cyclase/sGC) and downstream effectors that further transmit the signal within the cell. Nitric oxide transmits its downstream effects through either cyclic GMP (cGMP)-dependent or independent mechanisms.
7264	small GTPase mediated signal transduction	P	Any series of molecular signals in which a small monomeric GTPase relays one or more of the signals.
7265	Ras protein signal transduction	P	A series of molecular signals within the cell that are mediated by a member of the Ras superfamily of proteins switching to a GTP-bound active state.
7266	Rho protein signal transduction	P	A series of molecular signals within the cell that are mediated by a member of the Rho family of proteins switching to a GTP-bound active state.
7267	cell-cell signaling	P	Any process that mediates the transfer of information from one cell to another. This process includes signal transduction in the receiving cell and, where applicable, release of a ligand and any processes that actively facilitate its transport and presentation to the receiving cell. Examples include signaling via soluble ligands, via cell adhesion molecules and via gap junctions.
7268	chemical synaptic transmission	P	The vesicular release of classical neurotransmitter molecules from a neuron, across a chemical synapse, the subsequent activation of neurotransmitter receptors of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse.
7269	neurotransmitter secretion	P	The regulated release of neurotransmitter from the presynapse into the synaptic cleft via calcium regualated exocytosis during synaptic transmission.
7270	neuron-neuron synaptic transmission	P	The process of communication from a neuron to another neuron across a synapse.
7271	synaptic transmission, cholinergic	P	The process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse using the neurotransmitter acetylcholine.
7272	ensheathment of neurons	P	The process in which glial cells envelop neuronal cell bodies and/or axons to form an insulating layer. This can take the form of myelinating or non-myelinating ensheathment.
7274	neuromuscular synaptic transmission	P	The process of communication from a neuron to a muscle, across a synapse.
7275	multicellular organism development	P	The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).
7276	gamete generation	P	The generation and maintenance of gametes in a multicellular organism. A gamete is a haploid reproductive cell.
7277	pole cell development	P	The process whose specific outcome is the progression of the pole cell over time, from its formation to the mature structure.
7278	pole cell fate determination	P	The cell fate determination process in which a cell becomes capable of differentiating autonomously into a pole cell regardless of its environment; upon determination, the cell fate cannot be reversed.
7279	pole cell formation	P	Formation of a small group of cells (pole cells) at the posterior pole of the insect blastula. They are the first cells to cellularize after the arrival of nuclei at the end of the syncytial blastula stage and are the precursors to the insect germ cells.
7280	pole cell migration	P	The directed movement of a pole cell (germline progenitors in insects) from its site of production at the posterior pole of the embryo through to the site where the gonads will form.
7281	germ cell development	P	The process whose specific outcome is the progression of an immature germ cell over time, from its formation to the mature structure (gamete). A germ cell is any reproductive cell in a multicellular organism.
7282	cystoblast division	P	Any of the rounds of incomplete mitosis undergone by a cystoblast to form a cyst of interconnected cells.
7283	spermatogenesis	P	The process of formation of spermatozoa, including spermatocytogenesis and spermiogenesis.
7284	spermatogonial cell division	P	The mitotic divisions of the primary spermatogonial cell (a primordial male germ cell) to form secondary spermatogonia (primary spermatocytes).
7285	primary spermatocyte growth	P	The phase of growth and gene expression that male germ cells undergo as they enter the spermatocyte stage. The cells grow in volume and transcribe most of the gene products needed for the morphological events that follow meiosis.
7286	spermatid development	P	The process whose specific outcome is the progression of a spermatid over time, from its formation to the mature structure.
7287	Nebenkern assembly	P	Fusion of mitochondria during insect spermatid differentiation to form two masses, which wrap around each other to form a densely packed sphere called the Nebenkern.
7288	sperm axoneme assembly	P	The assembly and organization of the sperm flagellar axoneme, the bundle of microtubules and associated proteins that forms the core of the eukaryotic sperm flagellum, and is responsible for movement.
7289	spermatid nucleus differentiation	P	The specialization of the spermatid nucleus during the development of a spermatid into a mature male gamete competent for fertilization.
7290	spermatid nucleus elongation	P	The change in shape of the spermatid nucleus from a spherical structure to an elongated organelle, during the latter part of spermatid differentiation.
7291	sperm individualization	P	The resolution of the male germline syncytium or cyst into individual gametes by packaging each spermatid into its own plasma membrane.
7292	female gamete generation	P	Generation of the female gamete; specialised haploid cells produced by meiosis and along with a male gamete takes part in sexual reproduction.
7293	germarium-derived egg chamber formation	P	Construction of a stage-1 egg chamber in the anterior part of the germarium, from the progeny of germ-line and somatic stem cells. An example of this is found in Drosophila melanogaster.
7294	germarium-derived oocyte fate determination	P	The cell fate determination process in which a germarium-derived cell becomes capable of differentiating autonomously into an oocyte cell regardless of its environment; upon determination, the cell fate cannot be reversed. An example of this is found in Drosophila melanogaster.
7295	growth of a germarium-derived egg chamber	P	Growth of the egg chamber between the time it leaves the germarium and the onset of vitellogenesis. During this time both nurse cells and the oocyte undergo developmental changes including nuclear organization and cytoplasmic growth. An example of this is found in Drosophila melanogaster.
7296	vitellogenesis	P	The production of yolk. Yolk is a mixture of materials used for embryonic nutrition.
7297	ovarian follicle cell migration	P	The directed movement of an ovarian follicle cell that takes place during oogenesis. During egg chamber formation, follicle cells migrate to envelop the germ-line cysts and move in between cysts. At stage 10B, follicle cells migrate centripetally between the nurse cells and the oocyte, enclosing the anterior of the egg. An example of this is found in Drosophila melanogaster.
7298	border follicle cell migration	P	The directed movement of a border cell through the nurse cells to reach the oocyte. An example of this is found in Drosophila melanogaster.
7299	ovarian follicle cell-cell adhesion	P	The attachment of a somatic follicle cell to another somatic follicle cell or to its substratum, the germline cells. An example of this is found in Drosophila melanogaster.
7300	ovarian nurse cell to oocyte transport	P	Transfer of constituents synthesized in the ovarian nurse cells to the oocyte, through the ring canals, as the egg chamber is growing. An example of this is found in Drosophila melanogaster.
7301	female germline ring canal formation	P	Assembly of the intercellular bridges that connect the germ-line cells of a female cyst.
7302	nurse cell nucleus anchoring	P	Attachment of the nurse cell nucleus to the plasma membrane.
7303	cytoplasmic transport, nurse cell to oocyte	P	The directed movement of cytoplasmic constituents synthesized in the nurse cells to the oocyte.
7304	chorion-containing eggshell formation	P	The construction of a chorion-containing eggshell. An example of this is found in Drosophila melanogaster.
7305	vitelline membrane formation involved in chorion-containing eggshell formation	P	Construction of the vitelline membrane portion of a chorion-containing eggshell. An example of this is found in Drosophila melanogaster.
7306	eggshell chorion assembly	P	Construction of the chorion portion of the eggshell, which comprises the channels for gas exchange in an insect eggshell.
7307	eggshell chorion gene amplification	P	Amplification by up to 60-fold of the loci containing the chorion gene clusters. Amplification is necessary for the rapid synthesis of chorion proteins by the follicle cells, and occurs by repeated firing of one or more origins located within each gene cluster.
7308	oocyte construction	P	The synthesis, deposition, and organization of the materials in a cell of an ovary; where the cell can then undergo meiosis and form an ovum. An example of this is found in Drosophila melanogaster.
7309	oocyte axis specification	P	The establishment, maintenance and elaboration of an axis in the oocyte. An example of this is found in Drosophila melanogaster.
7310	oocyte dorsal/ventral axis specification	P	The establishment, maintenance and elaboration of the dorsal/ventral axis of the oocyte. An example of this is found in Drosophila melanogaster.
7311	maternal specification of dorsal/ventral axis, oocyte, germ-line encoded	P	Polarization of the oocyte along the dorsal-ventral axis, by a gene product encoded by cells of the germ line. An example of this is found in Drosophila melanogaster.
7312	oocyte nucleus migration involved in oocyte dorsal/ventral axis specification	P	The directed movement of the oocyte nucleus within the cell as part of the establishment and maintenance of the dorsal/ventral axis of the oocyte. An example of this is found in Drosophila melanogaster.
7313	maternal specification of dorsal/ventral axis, oocyte, soma encoded	P	Polarization of the oocyte along the dorsal-ventral axis, by a gene product encoded by somatic cells. An example of this is found in Drosophila melanogaster.
7314	oocyte anterior/posterior axis specification	P	Polarization of the oocyte along its anterior-posterior axis. An example of this is found in Drosophila melanogaster.
7315	pole plasm assembly	P	Establishment of the specialized cytoplasm found at the poles of the egg. An example of this is found in Drosophila melanogaster.
7316	pole plasm RNA localization	P	Any process in which RNA is transported to, or maintained in, the oocyte pole plasm. An example of this is found in Drosophila melanogaster.
7317	regulation of pole plasm oskar mRNA localization	P	Any process that modulates the frequency, rate or extent of the process in which oskar mRNA is transported to, or maintained in, the oocyte pole plasm.
7318	pole plasm protein localization	P	Any process in which a protein is transported to, or maintained in, the oocyte pole plasm. An example of this is found in Drosophila melanogaster.
7319	negative regulation of oskar mRNA translation	P	Any process that stops, prevents or reduces the rate that oskar mRNAs are effectively translated into protein.
7320	insemination	P	The introduction of semen or sperm into the genital tract of a female.
7321	sperm displacement	P	The physical displacement of sperm stored from previous mating encounters.
7323	peptide pheromone maturation	P	The generation of a mature, active peptide pheromone via processes unique to its processing and modification. An example of this process is found in Saccharomyces cerevisiae.
7329	positive regulation of transcription from RNA polymerase II promoter by pheromones	P	Any process involving pheromones that activates or increases the rate of transcription from an RNA polymerase II promoter.
7338	single fertilization	P	The union of male and female gametes to form a zygote.
7339	binding of sperm to zona pellucida	P	The process in which the sperm binds to the zona pellucida glycoprotein layer of the egg. The process begins with the attachment of the sperm plasma membrane to the zona pellucida and includes attachment of the acrosome inner membrane to the zona pellucida after the acrosomal reaction takes place.
7340	acrosome reaction	P	The discharge, by sperm, of a single, anterior secretory granule following the sperm's attachment to the zona pellucida surrounding the oocyte. The process begins with the fusion of the outer acrosomal membrane with the sperm plasma membrane and ends with the exocytosis of the acrosomal contents into the egg.
7341	penetration of zona pellucida	P	The infiltration by sperm of the zona pellucida to reach the oocyte. The process involves digestive enzymes from a modified lysosome called the acrosome, situated at the head of the sperm.
7342	fusion of sperm to egg plasma membrane	P	The binding and fusion of a sperm, having penetrated the zona pellucida, with the plasma membrane of the oocyte. Binding occurs at the posterior (post-acrosomal) region of the sperm head.
7343	egg activation	P	The process in which the egg becomes metabolically active, initiates protein and DNA synthesis and undergoes structural changes to its cortex and/or cytoplasm.
7344	pronuclear fusion	P	The merging of two pronuclei in a fertilized egg to fuse and produce a single zygotic genome.
7346	regulation of mitotic cell cycle	P	Any process that modulates the rate or extent of progress through the mitotic cell cycle.
7347	regulation of preblastoderm mitotic cell cycle	P	A cell cycle process that modulates the rate or extent of the progression through the preblastoderm mitotic cell cycle.
7348	regulation of syncytial blastoderm mitotic cell cycle	P	A cell cycle process that modulates the rate or extent of the progression through the syncytial blastoderm mitotic cell cycle.
7349	cellularization	P	The separation of a multi-nucleate cell or syncytium into individual cells. An example of this is found in Drosophila melanogaster embryo development.
7350	blastoderm segmentation	P	The hierarchical steps resulting in the progressive subdivision of the anterior/posterior axis of the embryo.
7351	tripartite regional subdivision	P	Subdivision of the embryo along the anterior/posterior axis into anterior, posterior and terminal regions.
7352	zygotic specification of dorsal/ventral axis	P	The specification of the dorsal/ventral axis of the embryo, through the products of genes expressed in the zygote.
7354	zygotic determination of anterior/posterior axis, embryo	P	The specification of the anterior/posterior axis of the embryo by products of genes expressed in the zygote; exemplified in insects by the gap genes, pair rule genes and segment polarity gene cascade.
7355	anterior region determination	P	Specification of the anterior (head and thoracic segments) of the embryo by the gap genes; exemplified in insects by the actions of hunchback gene product.
7356	thorax and anterior abdomen determination	P	Specification of the central (trunk) regions of the embryo by the gap genes; exemplified in insects by the actions of the Kruppel gene product.
7357	positive regulation of central gap gene transcription	P	The activation of genes encoding transcription factors in the central region of an insect embryo by a combination of maternal regulatory signals and interactions among themselves; exemplified by the activation of expression of the Drosophila Kruppel gene by the hunchback and bicoid gene products.
7358	establishment of central gap gene boundaries	P	Specification of the borders of central gap gene expression mediated largely by the effects of other gap genes; in insects this is exemplified by knirps repression of Kruppel.
7359	posterior abdomen determination	P	The regionalization process in which the posterior (abdominal) regions of the embryo are specified by the gap genes.
7360	positive regulation of posterior gap gene transcription	P	The activation of genes encoding transcription factors in the posterior region of an insect embryo by a combination of maternal regulatory signals and interactions among themselves; exemplified by the activation of expression of the Drosophila knirps gene.
7361	establishment of posterior gap gene boundaries	P	Specification of the borders of posterior gap gene expression mediated largely by the effects of other gap genes; in insects this is exemplified by hunchback and tailless repression of knirps.
7362	terminal region determination	P	Specification of the terminal regions (the two non-segmented ends) of the embryo by the gap genes; exemplified in insects by the actions of huckebein and tailless gene products.
7363	positive regulation of terminal gap gene transcription	P	The activation of genes encoding transcription factors at the anterior and posterior ends of an insect embryo by a combination of maternal regulatory signals and interactions among themselves; exemplified by the activation of expression of the Drosophila tailless and huckebein genes.
7364	establishment of terminal gap gene boundary	P	Specification of the borders of terminal gap gene expression mediated largely by the effects of other gap genes.
7365	periodic partitioning	P	The regionalization process that divides the spatial regions of an embryo into serially repeated regions.
7366	periodic partitioning by pair rule gene	P	Allocation of cells to parasegments in the embryo, through the action of overlapping series of pair rule gene activities.
7367	segment polarity determination	P	Division of the 14 parasegments of the embryo into anterior and posterior compartments; exemplified by the actions of the segment polarity gene products.
7368	determination of left/right symmetry	P	The establishment of an organism's body plan or part of an organism with respect to the left and right halves. The pattern can either be symmetric, such that the halves are mirror images, or asymmetric where the pattern deviates from this symmetry.
7369	gastrulation	P	A complex and coordinated series of cellular movements that occurs at the end of cleavage during embryonic development of most animals. The details of gastrulation vary from species to species, but usually result in the formation of the three primary germ layers, ectoderm, mesoderm and endoderm.
7370	ventral furrow formation	P	Formation of a ventral indentation (furrow) from the blastoderm epithelium, which is internalized to form a tube in the interior of the embryo, marking the start of gastrulation.
7371	ventral midline determination	P	The regionalization process in which the area where the ventral midline will form is specified.
7374	posterior midgut invagination	P	Formation of a cup-shaped invagination at the posterior end of the embryo, bringing the posterior midgut and hindgut primordia into the interior.
7375	anterior midgut invagination	P	Internalization of the anterior midgut into the interior of the embryo.
7376	cephalic furrow formation	P	Formation of a partial necklace of inturning tissue on the lateral sides of the embryo, along the dorsal-ventral axis. This furrow demarcates head from thorax in the developing protostome.
7377	germ-band extension	P	Elongation of the germ band on the ventral side of the embryo, accompanied by a halving in width. The elongation process pushes the posterior midgut invagination closed and compresses the amnioserosa further.
7378	amnioserosa formation	P	Formation of the amnioserosa, an epithelium that occupies a hole in the embryonic dorsal epidermis. This occurs by the transformation of a narrow strip of cells at the dorsal midline of the blastoderm from columnar to squamous cells, accompanied by a lateral shift.
7379	segment specification	P	The process in which segments assume individual identities; exemplified in insects by the actions of the products of the homeotic genes.
7380	specification of segmental identity, head	P	The specification of the characteristic structures of the head segments following establishment of segment boundaries. Identity is considered to be the aggregate of characteristics by which a structure is recognized.
7381	specification of segmental identity, labial segment	P	The specification of the characteristic structures of the labial segment following establishment of segment boundaries. Identity is considered to be the aggregate of characteristics by which a structure is recognized.
7382	specification of segmental identity, maxillary segment	P	The specification of the characteristic structures of the maxillary segment following establishment of segment boundaries. Identity is considered to be the aggregate of characteristics by which a structure is recognized.
7383	specification of segmental identity, antennal segment	P	The specification of the characteristic structures of the antennal segment following establishment of segment boundaries. Identity is considered to be the aggregate of characteristics by which a structure is recognized.
7384	specification of segmental identity, thorax	P	The specification of the characteristic structures of the thoracic segments following establishment of segment boundaries. Identity is considered to be the aggregate of characteristics by which a structure is recognized.
7385	specification of segmental identity, abdomen	P	The specification of the characteristic structures of the abdominal segments following establishment of segment boundaries. Identity is considered to be the aggregate of characteristics by which a structure is recognized.
7386	compartment pattern specification	P	The regionalization process in which embryonic segments are divided into compartments that will result in differences in cell differentiation.
7387	anterior compartment pattern formation	P	The process giving rise to specification of cell identity in the anterior compartments of the segmented embryo.
7388	posterior compartment specification	P	The process involved in the specification of cell identity in the posterior compartments of the segmented embryo.
7389	pattern specification process	P	Any developmental process that results in the creation of defined areas or spaces within an organism to which cells respond and eventually are instructed to differentiate.
7390	germ-band shortening	P	The spreading of the amnioserosa from its compressed state to cover the whole of the dorsal surface. Initiating in the thorax and spreading posteriorly, it is accompanied by the transition from a parasegmental to segmental division of the embryo.
7391	dorsal closure	P	The process during Drosophila embryogenesis whereby the ectodermal cells of the lateral epithelium stretch in a coordinated fashion to internalize the amnioserosa cells and close the embryo dorsally.
7392	initiation of dorsal closure	P	Events that occur at the start of dorsal closure.
7393	dorsal closure, leading edge cell fate determination	P	The cell fate determination process in which a cell within the dorsal ectoderm becomes capable of differentiating autonomously into a leading edge cell regardless of its environment; upon determination, the cell fate cannot be reversed.
7394	dorsal closure, elongation of leading edge cells	P	The change in shape of cells at the dorsal-most (leading) edge of the epidermis from being polygonal to being elongated in the dorsal/ventral axis.
7395	dorsal closure, spreading of leading edge cells	P	Dorsally-directed movement of a cell at the leading edge of the epithelium over the amnioserosa.
7396	suture of dorsal opening	P	Closure of the dorsal hole. Filopodia extending from each leading edge interdigitate at the dorsal midline and appear to prime the formation of adherens junctions between the two rows of leading edge cells. Newly formed septate junctions are also used to seal the dorsal hole.
7398	ectoderm development	P	The process whose specific outcome is the progression of the ectoderm over time, from its formation to the mature structure. In animal embryos, the ectoderm is the outer germ layer of the embryo, formed during gastrulation.
7399	nervous system development	P	The process whose specific outcome is the progression of nervous tissue over time, from its formation to its mature state.
7400	neuroblast fate determination	P	The cell fate determination process in which a cell becomes capable of differentiating autonomously into a neuroblast cell regardless of its environment; upon determination, the cell fate cannot be reversed. An example of this process is found in Mus musculus.
7402	ganglion mother cell fate determination	P	The cell fate determination process in which a cell becomes capable of differentiating autonomously into a ganglion mother cell regardless of its environment; upon determination, the cell fate cannot be reversed.
7403	glial cell fate determination	P	The cell fate determination process in which a cell becomes capable of differentiating autonomously into a glial cell regardless of its environment; upon determination, the cell fate cannot be reversed.
7405	neuroblast proliferation	P	The expansion of a neuroblast population by cell division. A neuroblast is any cell that will divide and give rise to a neuron.
7406	negative regulation of neuroblast proliferation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the proliferation of neuroblasts.
7407	neuroblast activation	P	A change in the morphology or behavior of a neuroblast resulting from exposure to an activating factor such as a cellular or soluble ligand.
7409	axonogenesis	P	De novo generation of a long process of a neuron, that carries efferent (outgoing) action potentials from the cell body towards target cells. Refers to the morphogenesis or creation of shape or form of the developing axon.
7411	axon guidance	P	The chemotaxis process that directs the migration of an axon growth cone to a specific target site in response to a combination of attractive and repulsive cues.
7412	axon target recognition	P	The process in which an axon recognizes and binds to a set of cells with which it may form stable connections.
7413	axonal fasciculation	P	The collection of axons into a bundle of rods, known as a fascicle.
7414	axonal defasciculation	P	Separation of axons away from a bundle of axons known as a fascicle.
7415	defasciculation of motor neuron axon	P	Separation of a motor axon away from a bundle of axons known as a fascicle.
7416	synapse assembly	P	The aggregation, arrangement and bonding together of a set of components to form a synapse. This process ends when the synapse is mature (functional).
7417	central nervous system development	P	The process whose specific outcome is the progression of the central nervous system over time, from its formation to the mature structure. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain and spinal cord. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord.
7418	ventral midline development	P	The process whose specific outcome is the progression of the ventral midline over time, from its formation to the mature structure. In protostomes (such as insects, snails and worms) as well as deuterostomes (vertebrates), the midline is an embryonic region that functions in patterning of the adjacent nervous tissue. The ventral midline in insects is a cell population extending along the ventral surface of the embryo and is the region from which cells detach to form the ventrally located nerve cords. In vertebrates, the midline is originally located dorsally. During development, it folds inwards and becomes the ventral part of the dorsally located neural tube and is then called the ventral midline, or floor plate.
7419	ventral cord development	P	The process whose specific outcome is the progression of the ventral cord over time, from its formation to the mature structure. The ventral cord is one of the distinguishing traits of the central nervous system of all arthropods (such as insects, crustaceans and arachnids) as well as many other invertebrates, such as the annelid worms.
7420	brain development	P	The process whose specific outcome is the progression of the brain over time, from its formation to the mature structure. Brain development begins with patterning events in the neural tube and ends with the mature structure that is the center of thought and emotion. The brain is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.).
7421	stomatogastric nervous system development	P	The process whose specific outcome is the progression of the stomatogastric nervous system over time, from its formation to the mature structure.
7422	peripheral nervous system development	P	The process whose specific outcome is the progression of the peripheral nervous system over time, from its formation to the mature structure. The peripheral nervous system is one of the two major divisions of the nervous system. Nerves in the PNS connect the central nervous system (CNS) with sensory organs, other organs, muscles, blood vessels and glands.
7423	sensory organ development	P	The process whose specific outcome is the progression of sensory organs over time, from its formation to the mature structure.
7424	open tracheal system development	P	The process whose specific outcome is the progression of an open tracheal system over time, from its formation to the mature structure. An open tracheal system is a respiratory system, a branched network of epithelial tubes that supplies oxygen to target tissues via spiracles. An example of this is found in Drosophila melanogaster.
7425	epithelial cell fate determination, open tracheal system	P	The cell fate determination process in which a cell becomes capable of differentiating autonomously into an epithelial cell within an open tracheal system regardless of its environment; upon determination, the cell fate cannot be reversed. Tracheal cells are set aside as 10 clusters of approximately 80 cells on each side of the embryo (termed tracheal placodes). An example of this is found in Drosophila melanogaster.
7426	tracheal outgrowth, open tracheal system	P	The projection of branches of an open tracheal system towards their target tissues. An example of this is found in Drosophila melanogaster.
7427	epithelial cell migration, open tracheal system	P	The orderly movement of epithelial cells during development of an open tracheal system. An example of this is found in Drosophila melanogaster.
7428	primary branching, open tracheal system	P	Formation of primary branches in the open tracheal system. These form from small groups of cells that migrate out at specific positions, organizing into tubes as they migrate. An example of this is found in Drosophila melanogaster.
7429	secondary branching, open tracheal system	P	Sprouting of secondary branches in an open tracheal system. These form from the tips of primary branches and are formed by individual cells that roll up into unicellular tubes. An example of this is found in Drosophila melanogaster.
7430	terminal branching, open tracheal system	P	Formation of terminal branches in the open tracheal system. These are long cytoplasmic extensions that form fine tubules that transport oxygen directly to the tissues. An example of the process is found in Drosophila melanogaster.
7431	salivary gland development	P	The process whose specific outcome is the progression of the salivary gland over time, from its formation to the mature structure. Salivary glands include any of the saliva-secreting exocrine glands of the oral cavity.
7432	salivary gland boundary specification	P	Determination of where the salivary gland forms, the total number of salivary gland cells and how many cells are allocated to each of the specialised cell types within the salivary gland.
7433	larval salivary gland boundary specification	P	Determination in a larval organism of where the salivary gland forms, the total number of salivary gland cells and how many cells are allocated to each of the specialised cell types within the salivary gland.
7434	adult salivary gland boundary specification	P	Determination in an adult organism of where the salivary gland forms, the total number of salivary gland cells and how many cells are allocated to each of the specialised cell types within the salivary gland.
7435	salivary gland morphogenesis	P	The process in which the anatomical structures of the salivary gland are generated and organized.
7436	larval salivary gland morphogenesis	P	The process, occurring in the larva, by which the anatomical structures of the salivary gland are generated and organized.
7437	adult salivary gland morphogenesis	P	The process in which the anatomical structures of the adult salivary gland are generated and organized.
7438	oenocyte development	P	The process whose specific outcome is the progression of the oenocyte over time, from its formation to the mature structure. The oenocytes are large secretory cells found in clusters underlying the epidermis of larval abdominal segments.
7439	ectodermal digestive tract development	P	The process whose specific outcome is the progression of the ectodermal digestive tract over time, from its formation to the mature structure. The ectodermal digestive tract includes those portions that are derived from ectoderm.
7440	foregut morphogenesis	P	The process in which the anatomical structures of the foregut are generated and organized.
7441	anterior midgut (ectodermal) morphogenesis	P	The process in which the anatomical structures of the anterior midgut (ectodermal) are generated and organized.
7442	hindgut morphogenesis	P	The process in which the anatomical structures of the hindgut are generated and organized.
7443	Malpighian tubule morphogenesis	P	The process in which the anatomical structures of the Malpighian tubule are generated and organized. This process takes place entirely during the embryonic phase. A Malpighian tubule is a fine, thin-walled excretory tubule in insects which leads into the posterior part of the gut.
7444	imaginal disc development	P	The process whose specific outcome is the progression of the imaginal disc over time, from its formation to the metamorphosis to form adult structures. Imaginal discs are epithelial infoldings in the larvae of holometabolous insects that develop into adult structures (legs, antennae, wings, etc.).
7445	determination of imaginal disc primordium	P	Allocation of embryonic cells to the imaginal disc founder populations, groups of cells that are committed to contribute to the formation of an imaginal disc compartment.
7446	imaginal disc growth	P	The increase in mass of imaginal discs by cell proliferation prior to metamorphosis. Imaginal discs are epithelial infoldings in the larvae of holometabolous insects that develop into adult structures (legs, antennae, wings, etc.) during metamorphosis from larval to adult form.
7447	imaginal disc pattern formation	P	The regionalization process that results in defined areas of the imaginal disc that will undergo specific cell differentaiton. Imaginal discs are epithelial infoldings in the larvae of holometabolous insects that develop into adult appendages (legs, antennae, wings, etc.) during metamorphosis from larval to adult form.
7448	anterior/posterior pattern specification, imaginal disc	P	The establishment, maintenance and elaboration of the anterior/posterior axis of the imaginal disc. Imaginal discs are epithelial infoldings in the larvae of holometabolous insects that rapidly develop into adult appendages during metamorphosis from larval to adult form.
7449	proximal/distal pattern formation, imaginal disc	P	The establishment, maintenance and elaboration of the proximal/distal axis of the imaginal disc. Imaginal disks are masses of hypodermic cells, carried by the larvae of some insects after leaving the egg, from which masses the wings and legs of the adult are subsequently formed.
7450	dorsal/ventral pattern formation, imaginal disc	P	The establishment, maintenance and elaboration of the dorsal/ventral axis of the imaginal disc. Imaginal disks are masses of hypodermic cells, carried by the larvae of some insects after leaving the egg, from which masses the wings and legs of the adult are subsequently formed.
7451	dorsal/ventral lineage restriction, imaginal disc	P	Formation and/or maintenance of a lineage boundary between dorsal and ventral compartments that cells cannot cross, thus separating the populations of cells in each compartment.
7453	clypeo-labral disc morphogenesis	P	The process in which the anatomical structures derived from the clypeo-labral disc are generated and organized. This includes the transformation of a clypeo-labal imaginal disc from a monolayered epithelium in the larvae of holometabolous insects into recognizable adult structures including the labrum, anterior and posterior cibarial plates, fish trap bristles, epistomal sclerite and clypeus.
7454	labial disc morphogenesis	P	The process in which the anatomical structures derived from the labial disc are generated and organized. This includes the transformation of a labial imaginal disc from a monolayered epithelium in the larvae of holometabolous insects into recognizable adult structures including parts of the proboscis.
7455	eye-antennal disc morphogenesis	P	The process in which the anatomical structures derived from the eye-antennal disc are generated and organized. This includes the transformation of an eye-antennal imaginal disc from a monolayered epithelium in the larvae of holometabolous insects into recognizable adult structures including the eye, antenna, head capsule and maxillary palps.
7458	progression of morphogenetic furrow involved in compound eye morphogenesis	P	The morphogenetic furrow is a dorsoventral indentation which sweeps anteriorly across the eye disc. Ommatidia begin to form along the furrow, resulting in a graded series of ommatidial development across the anterior/posterior axis of the disc.
7460	R8 cell fate commitment	P	The process in which the R8 photoreceptor commits to its cell fate. The R8 receptor contributes the central part of the rhabdomere in the basal parts of the ommatidium.
7462	R1/R6 cell fate commitment	P	The process in which the R1/R6 photoreceptors commit to their cell fate. R1 and R6 are paired photoreceptors which contribute the outer rhabdomeres.
7463	R2/R5 cell fate commitment	P	The process in which the R2/R5 photoreceptors commit to their cell fate. R2 and R5 are paired photoreceptors which contribute the outer rhabdomeres.
7464	R3/R4 cell fate commitment	P	The process in which the R3/R4 photoreceptors commit to their cell fate. R3 and R4 are paired photoreceptors which contribute the outer rhabdomeres.
7465	R7 cell fate commitment	P	The process in which the R7 photoreceptor commits to its cell fate. The R7 receptor contributes the central part of the rhabdomere in the apical parts of the ommatidium.
7468	regulation of rhodopsin gene expression	P	Any process that modulates the frequency, rate or extent of rhodopsin gene expression. This includes transcriptional, translational, or posttranslational regulation.
7469	antennal development	P	The process whose specific outcome is the progression of the antenna over time, from its formation to the mature structure. The antenna are the sensory structures on the head that are capable of detecting various environmental stimuli.
7470	prothoracic disc morphogenesis	P	The process in which the anatomical structures derived from the prothoracic disc are generated and organized. This includes the transformation of a prothoracic imaginal disc from a monolayered epithelium in the larvae of holometabolous insects into the recognizable adult humerous and anterior spiracle.
7472	wing disc morphogenesis	P	The process in which the anatomical structures derived from the wing disc are generated and organized. This includes the transformation of a wing imaginal disc from a monolayered epithelium in the larvae of holometabolous insects into recognizable adult structures including the wing hinge, wing blade and pleura.
7473	wing disc proximal/distal pattern formation	P	The establishment, maintenance and elaboration of the proximal/distal axis of the wing disc, a precursor to the adult wing.
7474	imaginal disc-derived wing vein specification	P	The regionalization process in which the area of a imaginal disc-derived wing that will form a wing vein is specified.
7475	apposition of dorsal and ventral imaginal disc-derived wing surfaces	P	The coming together of the dorsal and ventral surfaces of the imaginal disc-derived wing during the conversion of a folded single layered wing disc to a flat bilayered wing.
7476	imaginal disc-derived wing morphogenesis	P	The process in which the anatomical structures of the imaginal disc-derived wing are generated and organized. The wing is an appendage modified for flying.
7477	notum development	P	The process whose specific outcome is the progression of the dorsal part of the body over time, from its formation to the mature structure.
7478	leg disc morphogenesis	P	The process in which the anatomical structures derived from the leg disc are generated and organized. This includes the transformation of a leg imaginal disc from a monolayered epithelium in the larvae of holometabolous insects into recognizable adult structures including the leg, coxa and ventral thoracic pleura.
7479	leg disc proximal/distal pattern formation	P	The establishment, maintenance and elaboration of the proximal/distal axis of the leg imaginal disc, a precursor to the adult leg.
7480	imaginal disc-derived leg morphogenesis	P	The process in which the anatomical structures of a leg derived from an imaginal disc are generated and organized. A leg is a limb on which an animal walks and stands. An example of this is found in Drosophila melanogaster.
7481	haltere disc morphogenesis	P	The process in which the anatomical structures derived from the haltere disc are generated and organized. This includes the transformation of a haltere imaginal disc from a monolayered epithelium in the larvae of holometabolous insects into the recognizable adult capitellum, pedicel, haltere sclerite, metathoracic spiracle and metanotum.
7482	haltere development	P	The process whose specific outcome is the progression of the haltere over time, from its formation to the mature structure. The haltere is the club-shaped 'balancers' found on each side of the metathorax among the true flies (Diptera). They are the much-modified hind wings.
7483	genital disc morphogenesis	P	The process in which the anatomical structures derived from the genital disc are generated and organized. This includes the transformation of a genital imaginal disc from a monolayered epithelium in the larvae of holometabolous insects into the recognizable adult genital structures, the anal plates and the hind gut.
7484	imaginal disc-derived genitalia development	P	The process whose specific outcome is the progression of the genitalia over time, from formation as part of the genital disc to the mature structure. An example of this is found in Drosophila melanogaster.
7485	imaginal disc-derived male genitalia development	P	The process whose specific outcome is the progression of the male genitalia over time, from formation as part of the genital disc to the mature structure. An example of this is found in Drosophila melanogaster.
7486	imaginal disc-derived female genitalia development	P	The process whose specific outcome is the progression of the female genitalia over time, from formation as part of the genital disc to the mature structure. An example of this is found in Drosophila melanogaster.
7487	analia development	P	The process whose specific outcome is the progression of the analia over time, from its formation to the mature structure. The analia is the posterior-most vertral appendage that develops from the genital disc. An example of this process is analia development in Drosophila melanogaster.
7488	histoblast morphogenesis	P	The process in which the anatomical structures derived from the histoblast disc are generated and organized. This includes the transformation of histoblast cells into adult structures during pupal metamorphosis. Histoblast cells are cells founded in the embryo that are the progenitors to the adult abdomen.
7489	maintenance of imaginal histoblast diploidy	P	The negative regulation of the differentiation of polytenized larval hypodermal cells from abdominal histoblasts. The abdominal histoblasts remain a small cluster of diploid cells among the polytenized larval hypodermal cells.
7490	tergite morphogenesis	P	The process in which the anatomical structures of the tergite are generated and organized. The tergite is the primary plate or sclerite forming the dorsal surface of any insect body segment.
7491	sternite morphogenesis	P	The process in which the anatomical structures of the sternite are generated and organized. The sternite is the plate or sclerite on the underside of a body segment.
7492	endoderm development	P	The process whose specific outcome is the progression of the endoderm over time, from its formation to the mature structure. The endoderm is the innermost germ layer that develops into the gastrointestinal tract, the lungs and associated tissues.
7493	endodermal cell fate determination	P	The cell fate determination process in which a cell becomes capable of differentiating autonomously into an endoderm cell regardless of its environment; upon determination, the cell fate cannot be reversed.
7494	midgut development	P	The process whose specific outcome is the progression of the midgut over time, from its formation to the mature structure. The midgut is the middle part of the alimentary canal from the stomach, or entrance of the bile duct, to, or including, the large intestine.
7495	visceral mesoderm-endoderm interaction involved in midgut development	P	The process of cell-cell signaling between visceral mesoderm cells and endoderm cells that is involved in the differentiation of cells in the midgut.
7496	anterior midgut development	P	The process whose specific outcome is the progression of the anterior midgut over time, from its formation to the mature structure.
7497	posterior midgut development	P	The process whose specific outcome is the progression of the posterior midgut over time, from its formation to the mature structure.
7498	mesoderm development	P	The process whose specific outcome is the progression of the mesoderm over time, from its formation to the mature structure. The mesoderm is the middle germ layer that develops into muscle, bone, cartilage, blood and connective tissue.
7499	ectoderm and mesoderm interaction	P	A cell-cell signaling process occurring between the two gastrulation-generated layers of the ectoderm and the mesoderm.
7500	mesodermal cell fate determination	P	The cell fate determination process in which a cell becomes capable of differentiating autonomously into a mesoderm cell regardless of its environment; upon determination, the cell fate cannot be reversed.
7501	mesodermal cell fate specification	P	The cell fate determination process in which a cell becomes capable of differentiating autonomously into a mesoderm cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.
7502	digestive tract mesoderm development	P	The process whose specific outcome is the progression of the digestive tract mesoderm over time, from its formation to the mature structure. The digestive tract mesoderm is portion of the middle layer of the three primary germ layers of the embryo which will go on to form part of the digestive tract of the organism.
7503	fat body development	P	The process whose specific outcome is the progression of the fat body over time, from its formation to the mature structure. A fat body is an insect gland dorsal to the insect gut, with a function analogous to that of the vertebrate liver. It is a storage organ for fats, glycogen and protein and is a major site of intermediary metabolism.
7504	larval fat body development	P	The process whose specific outcome is the progression of the larval fat body over time, from its formation to the mature structure. The larval fat body consists of a bilaterally symmetrical monolayer of cells lying between the gut and the muscles of the body wall. As in other tissues of the larva, the cells of the fat body complete their divisions in the embryo and increase in size and ploidy during larval life.
7505	adult fat body development	P	The process whose specific outcome is the progression of the adult fat body over time, from its formation to the mature structure. Larval fat body cells that remain at eclosion degenerate in the first 2 to 4 days of adult life, leaving behind the smaller cells of the adult fat body.
7506	gonadal mesoderm development	P	The process whose specific outcome is the progression of the gonadal mesoderm over time, from its formation to the mature structure. The gonadal mesoderm is the middle layer of the three primary germ layers of the embryo which will go on to form the gonads of the organism.
7507	heart development	P	The process whose specific outcome is the progression of the heart over time, from its formation to the mature structure. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood.
7508	larval heart development	P	The process whose specific outcome is the progression of the larval heart over time, from its formation to the mature structure. In Drosophila the larval heart (dorsal vessel) is a continuous tube of mesodormal cells that runs beneath the dorsal midline of the epidermis, divided into an anterior aorta and a posterior heart proper.
7509	mesoderm migration involved in gastrulation	P	The migration of mesodermal cells during gastrulation to help establish the multilayered body plan of the organism.
7510	cardioblast cell fate determination	P	The cell fate determination process in which a cell becomes capable of differentiating autonomously into a cardioblast cell regardless of its environment; upon determination, the cell fate cannot be reversed. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.
7512	adult heart development	P	The process whose specific outcome is the progression of the adult heart over time, from its formation to the mature structure.
7516	hemocyte development	P	The process whose specific outcome is the progression of the hemocyte over time, from its formation to the mature structure. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen.
7517	muscle organ development	P	The process whose specific outcome is the progression of the muscle over time, from its formation to the mature structure. The muscle is an organ consisting of a tissue made up of various elongated cells that are specialized to contract and thus to produce movement and mechanical work.
7518	myoblast fate determination	P	The cell fate determination process in which a cell becomes capable of differentiating autonomously into a myoblast regardless of its environment; upon determination, the cell fate cannot be reversed. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.
7519	skeletal muscle tissue development	P	The developmental sequence of events leading to the formation of adult skeletal muscle tissue. The main events are: the fusion of myoblasts to form myotubes that increase in size by further fusion to them of myoblasts, the formation of myofibrils within their cytoplasm and the establishment of functional neuromuscular junctions with motor neurons. At this stage they can be regarded as mature muscle fibers.
7520	myoblast fusion	P	A process in which non-proliferating myoblasts fuse to existing fibers or to myotubes to form new fibers. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.
7521	muscle cell fate determination	P	The cell fate determination process in which a cell becomes capable of differentiating autonomously into a muscle cell regardless of its environment; upon determination, the cell fate cannot be reversed.
7522	visceral muscle development	P	The process whose specific outcome is the progression of the visceral muscle over time, from its formation to the mature structure.
7523	larval visceral muscle development	P	The process whose specific outcome is the progression of the larval visceral muscle over time, from its formation to the mature structure.
7524	adult visceral muscle development	P	The process whose specific outcome is the progression of the adult visceral muscle over time, from its formation to the mature structure.
7525	somatic muscle development	P	The process whose specific outcome is the progression of the somatic muscle over time, from its formation to the mature structure. Somatic muscles are striated muscle structures that connect to the exoskeleton or cuticle.
7526	larval somatic muscle development	P	The process whose specific outcome is the progression of the larval somatic muscle over time, from its formation to the mature structure.
7527	adult somatic muscle development	P	The process whose specific outcome is the progression of the adult somatic muscle over time, from its formation to the mature structure.
7528	neuromuscular junction development	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a neuromuscular junction.
7529	establishment of synaptic specificity at neuromuscular junction	P	The biological process in which a synapse between a motor neuron and a muscle is initially formed.
7530	sex determination	P	Any process that establishes and transmits the specification of sexual status of an individual organism.
7531	mating type determination	P	Any process that establishes and transmits the specification of mating type upon an individual. Mating types are the equivalent in microorganisms of the sexes in higher organisms.
7532	regulation of mating-type specific transcription, DNA-templated	P	Any mating-type specific process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
7533	mating type switching	P	The conversion of a single-cell organism from one mating type to another by the precise replacement of a DNA sequence at the expressed mating type locus with a copy of a sequence from a donor locus.
7534	gene conversion at mating-type locus	P	The conversion of the mating-type locus from one allele to another resulting from the recombinational repair of a site-specific double-strand break at the mating-type locus with information from a silent donor sequence. There is no reciprocal exchange of information because the mating-type locus copies information from the donor sequence and the donor sequence remains unchanged.
7535	donor selection	P	The process that determines which donor locus a cell uses, in preference to another, in mating type switching.
7536	activation of recombination (HML)	P	The activation of recombination at a mating type locus, such that it is used in preference to the other donor locus for mating type switching; exemplified by the HML locus and surrounding sequences on Chromosome III in Saccharomyces cerevisiae.
7537	inactivation of recombination (HML)	P	The inactivation of recombination at sequences around a mating type donor locus, with the consequence that the other donor is the only one available for mating type switching; exemplified by the HML locus and surrounding sequences on Chromosome III in Saccharomyces cerevisiae.
7538	primary sex determination	P	The sex determination process that results in the initial specification of sexual status of an individual organism.
7539	primary sex determination, soma	P	The transmission of information about sexual status from the initial, general, determination to signals specific to the soma.
7540	sex determination, establishment of X:A ratio	P	The developmental process in which an organism senses the number of X chromosomes and autosomes in its genomic complement and responds to it.
7541	sex determination, primary response to X:A ratio	P	The developmental process in which an organism interprets its X to autosomal chromosomal complement.
7542	primary sex determination, germ-line	P	The transmission of information about sexual status, from the initial general determination, to signals specific to the germ-line.
7543	sex determination, somatic-gonadal interaction	P	The process that mediates the interactions between somatic cells and gonadal cells that ultimately results in the specification of sexual status of the organism.
7545	processes downstream of sex determination signal	P	The sex determination processes that take place after the initial transmission of the sexual phenotype to specific information pathways.
7546	somatic processes downstream of sex determination signal	P	The events determining the somatic sexual phenotype after the initial transmission of that phenotype to soma-specific information pathways.
7547	germ-line processes downstream of sex determination signal	P	The events determining the germ-line sexual phenotype after the initial transmission of that phenotype to germ-line-specific information pathways.
7548	sex differentiation	P	The establishment of the sex of an organism by physical differentiation.
7549	dosage compensation	P	Compensating for the two-fold variation in X:autosome chromosome ratios between sexes by a global activation or inactivation of all, or most of, genes on one or both of the X chromosomes.
7552	metamorphosis	P	A biological process in which an animal physically develops after birth or hatching, involving a conspicuous and relatively abrupt change in the animal's form or structure. Examples include the change from tadpole to frog, and the change from larva to adult. An example of this is found in Drosophila melanogaster.
7553	regulation of ecdysteroid metabolic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving ecdysteroids, a group of polyhydroxylated ketosteroids which initiate post-embryonic development, including the metamorphosis of immature forms and the development of the reproductive system and the maturation of oocytes in adult females.
7554	regulation of ecdysteroid biosynthetic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of ecdysteroids.
7555	regulation of ecdysteroid secretion	P	Any process that modulates the frequency, rate or extent of the regulated release of ecdysteroid from a cell.
7556	regulation of juvenile hormone metabolic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving juvenile hormone.
7557	regulation of juvenile hormone biosynthetic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of juvenile hormone.
7558	regulation of juvenile hormone secretion	P	Any process that modulates the frequency, rate or extent of juvenile hormone secretion.
7560	imaginal disc morphogenesis	P	The process in which the anatomical structures derived from an imaginal disc are generated and organized. The imaginal discs are epithelial infoldings in the larvae of holometabolous insects that develop into adult appendages (legs, antennae, wings, etc.) during metamorphosis from larval to adult form.
7561	imaginal disc eversion	P	The eversion (turning inside out) of imaginal discs from their peripodial sacs, resulting in movement of the epithelium to the outside of the larval epidermis.
7562	eclosion	P	The emergence of an adult insect from a pupa case.
7563	regulation of eclosion	P	Any process that modulates the frequency, rate or extent of the emergence of an insect from a pupa-case or of a larva from an egg.
7564	regulation of chitin-based cuticle tanning	P	Any process that modulates the frequency, rate or extent of chitin-based cuticular tanning.
7565	female pregnancy	P	The set of physiological processes that allow an embryo or foetus to develop within the body of a female animal. It covers the time from fertilization of a female ovum by a male spermatozoon until birth.
7566	embryo implantation	P	Attachment of the blastocyst to the uterine lining.
7567	parturition	P	The reproductive process in which the parent is separated from its offspring either by giving birth to live young or by laying eggs.
7568	aging	P	A developmental process that is a deterioration and loss of function over time. Aging includes loss of functions such as resistance to disease, homeostasis, and fertility, as well as wear and tear. Aging includes cellular senescence, but is more inclusive. May precede death and may succeed developmental maturation (GO:0021700).
7569	cell aging	P	An aging process that has as participant a cell after a cell has stopped dividing. Cell aging may occur when a cell has temporarily stopped dividing through cell cycle arrest (GO:0007050) or when a cell has permanently stopped dividing, in which case it is undergoing cellular senescence (GO:0090398). May precede cell death (GO:0008219) and succeed cell maturation (GO:0048469).
7571	age-dependent general metabolic decline	P	A developmental process that arises as the cell progresses toward the end of its lifespan and cause changes cellular metabolism, resulting in a decline in cell function; for example, one aspect of general metabolic decline is a decrease in the efficiency of protein synthesis.
7576	nucleolar fragmentation	P	The cell aging process that results in the nucleolus breaking down into fragments.
7580	extrachromosomal circular DNA accumulation involved in cell aging	P	Increase in abundance, as cells age, of circular DNA molecules that originate in the chromosome but are excised and circularized, often by intramolecular homologous recombination between direct tandem repeats, and replicated independently of chromosomal replication.
7584	response to nutrient	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nutrient stimulus.
7585	respiratory gaseous exchange	P	The process of gaseous exchange between an organism and its environment. In plants, microorganisms, and many small animals, air or water makes direct contact with the organism's cells or tissue fluids, and the processes of diffusion supply the organism with dioxygen (O2) and remove carbon dioxide (CO2). In larger animals the efficiency of gaseous exchange is improved by specialized respiratory organs, such as lungs and gills, which are ventilated by breathing mechanisms.
7586	digestion	P	The whole of the physical, chemical, and biochemical processes carried out by multicellular organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism.
7588	excretion	P	The elimination by an organism of the waste products that arise as a result of metabolic activity. These products include water, carbon dioxide (CO2), and nitrogenous compounds.
7589	body fluid secretion	P	The controlled release of a fluid by a cell or tissue in an animal.
7591	molting cycle, chitin-based cuticle	P	The periodic shedding of part or all of a chitin-based cuticle, which is then replaced by a new cuticle. An example of this is found in Drosophila melanogaster.
7593	chitin-based cuticle sclerotization	P	The process of hardening of a chitin-based cuticle.
7594	puparial adhesion	P	The adhesion of the puparia of Diptera to their substrate; normally effected by a 'glue' secreted by the larval salivary gland and expectorated at the time of pupariation.
7595	lactation	P	The secretion of milk by the mammary gland.
7596	blood coagulation	P	The sequential process in which the multiple coagulation factors of the blood interact, ultimately resulting in the formation of an insoluble fibrin clot; it may be divided into three stages: stage 1, the formation of intrinsic and extrinsic prothrombin converting principle; stage 2, the formation of thrombin; stage 3, the formation of stable fibrin polymers.
7597	blood coagulation, intrinsic pathway	P	A protein activation cascade that contributes to blood coagulation and consists of the interactions among high molecular weight kininogen, prekallikrein, and factor XII that lead to the activation of clotting factor X.
7598	blood coagulation, extrinsic pathway	P	A protein activation cascade that contributes to blood coagulation and consists of the self-limited process linking exposure and activation of tissue factor to the activation of clotting factor X.
7599	hemostasis	P	The stopping of bleeding (loss of body fluid) or the arrest of the circulation to an organ or part.
7600	sensory perception	P	The series of events required for an organism to receive a sensory stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process.
7601	visual perception	P	The series of events required for an organism to receive a visual stimulus, convert it to a molecular signal, and recognize and characterize the signal. Visual stimuli are detected in the form of photons and are processed to form an image.
7602	phototransduction	P	The sequence of reactions within a cell required to convert absorbed photons into a molecular signal.
7603	phototransduction, visible light	P	The sequence of reactions within a cell required to convert absorbed photons from visible light into a molecular signal. A visible light stimulus is electromagnetic radiation that can be perceived visually by an organism; for organisms lacking a visual system, this can be defined as light with a wavelength within the range 380 to 780 nm.
7604	phototransduction, UV	P	The sequence of reactions within a cell required to convert absorbed photons from UV light into a molecular signal; ultraviolet radiation is electromagnetic radiation with a wavelength in the range of 10 to 400 nanometers.
7605	sensory perception of sound	P	The series of events required for an organism to receive an auditory stimulus, convert it to a molecular signal, and recognize and characterize the signal. Sonic stimuli are detected in the form of vibrations and are processed to form a sound.
7606	sensory perception of chemical stimulus	P	The series of events required for an organism to receive a sensory chemical stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process.
7608	sensory perception of smell	P	The series of events required for an organism to receive an olfactory stimulus, convert it to a molecular signal, and recognize and characterize the signal. Olfaction involves the detection of chemical composition of an organism's ambient medium by chemoreceptors. This is a neurological process.
7610	behavior	P	The internally coordinated responses (actions or inactions) of whole living organisms (individuals or groups) to internal or external stimuli.
7611	learning or memory	P	The acquisition and processing of information and/or the storage and retrieval of this information over time.
7612	learning	P	Any process in an organism in which a relatively long-lasting adaptive behavioral change occurs as the result of experience.
7613	memory	P	The activities involved in the mental information processing system that receives (registers), modifies, stores, and retrieves informational stimuli. The main stages involved in the formation and retrieval of memory are encoding (processing of received information by acquisition), storage (building a permanent record of received information as a result of consolidation) and retrieval (calling back the stored information and use it in a suitable way to execute a given task).
7614	short-term memory	P	The memory process that deals with the storage, retrieval and modification of information received a short time (up to about 30 minutes) ago. This type of memory is typically dependent on direct, transient effects of second messenger activation.
7615	anesthesia-resistant memory	P	The memory process that results in the formation of consolidated memory resistant to disruption of the patterned activity of the brain, without requiring protein synthesis.
7616	long-term memory	P	The memory process that deals with the storage, retrieval and modification of information a long time (typically weeks, months or years) after receiving that information. This type of memory is typically dependent on gene transcription regulated by second messenger activation.
7617	mating behavior	P	The behavioral interactions between organisms for the purpose of mating, or sexual reproduction resulting in the formation of zygotes.
7618	mating	P	The pairwise union of individuals for the purpose of sexual reproduction, ultimately resulting in the formation of zygotes.
7619	courtship behavior	P	The behavioral interactions between organisms for the purpose of attracting sexual partners.
7620	copulation	P	The act of sexual union between male and female, involving the transfer of sperm.
7621	negative regulation of female receptivity	P	Any process that stops, prevents or reduces the receptiveness of a female to male advances.
7622	rhythmic behavior	P	The specific behavior of an organism that recur with measured regularity.
7623	circadian rhythm	P	Any biological process in an organism that recurs with a regularity of approximately 24 hours.
7624	ultradian rhythm	P	The specific actions or reactions of an organism that recur with a regularity more frequent than every 24 hours.
7625	grooming behavior	P	The specific behavior of an organism relating to grooming, cleaning and brushing to remove dirt and parasites.
7626	locomotory behavior	P	The specific movement from place to place of an organism in response to external or internal stimuli. Locomotion of a whole organism in a manner dependent upon some combination of that organism's internal state and external conditions.
7628	adult walking behavior	P	The behavior of an adult relating to the progression of that organism along the ground by the process of lifting and setting down each leg.
7629	flight behavior	P	The response to external or internal stimuli that results in the locomotory process of flight. Flight is the self-propelled movement of an organism through the air.
7630	jump response	P	The sudden, usually upward, movement off the ground or other surface through sudden muscular effort in the legs, following exposure to an external stimulus.
7631	feeding behavior	P	Behavior associated with the intake of food.
7632	visual behavior	P	The behavior of an organism in response to a visual stimulus.
7633	pattern orientation	P	The actions or reactions of an individual in response to the orientation of a visual pattern. This is exemplified by some classes of insects which are able to detect and learn the orientation of a set of stripes and subsequently behaviorally discriminate between horizontal, vertical or 45 degree stripes.
7634	optokinetic behavior	P	The behavior of an organism pertaining to movement of the eyes and of objects in the visual field, as in nystagmus.
7635	chemosensory behavior	P	Behavior that is dependent upon the sensation of chemicals.
7636	chemosensory jump behavior	P	The sudden, usually upward, movement off the ground or other surface through sudden muscular effort in the legs, following exposure to a chemical substance.
7637	proboscis extension reflex	P	The extension, through direct muscle actions, of the proboscis (the trunk-like extension of the mouthparts on the adult external head) in response to a sugar stimulus.
7638	mechanosensory behavior	P	Behavior that is dependent upon the sensation of a mechanical stimulus.
7639	homeostasis of number of meristem cells	P	Any biological process involved in the maintenance of the steady-state number of cells within a population of cells in the meristem.
8002	lamina lucida	C	The electron-lucent layer of the basal lamina adjacent to the basal plasma membrane of the cells that rest on the lamina.
8003	lamina densa	C	The electron-dense layer of the basal lamina; lies just below the lamina lucida.
8004	lamina reticularis	C	A layer of the basal lamina that contains collagen fibrils and connects the basal lamina to the underlying connective tissue.
8009	chemokine activity	F	The function of a family of small chemotactic cytokines; their name is derived from their ability to induce directed chemotaxis in nearby responsive cells. All chemokines possess a number of conserved cysteine residues involved in intramolecular disulfide bond formation. Some chemokines are considered pro-inflammatory and can be induced during an immune response to recruit cells of the immune system to a site of infection, while others are considered homeostatic and are involved in controlling the migration of cells during normal processes of tissue maintenance or development. Chemokines are found in all vertebrates, some viruses and some bacteria.
8010	structural constituent of chitin-based larval cuticle	F	The action of a molecule that contributes to the structural integrity of the chitin-based cuticle of a larva. An example of this is found in Drosophila melanogaster.
8011	structural constituent of pupal chitin-based cuticle	F	The action of a molecule that contributes to the structural integrity of the chitin-based cuticle of a pupa. An example of this is found in Drosophila melanogaster.
8012	structural constituent of adult chitin-based cuticle	F	The action of a molecule that contributes to the structural integrity of the chitin-based cuticle of an adult organism. An example of this is found in Drosophila melanogaster.
8013	beta-catenin binding	F	Interacting selectively and non-covalently with the beta subunit of the catenin complex.
8015	blood circulation	P	The flow of blood through the body of an animal, enabling the transport of nutrients to the tissues and the removal of waste products.
8016	regulation of heart contraction	P	Any process that modulates the frequency, rate or extent of heart contraction. Heart contraction is the process in which the heart decreases in volume in a characteristic way to propel blood through the body.
8017	microtubule binding	F	Interacting selectively and non-covalently with microtubules, filaments composed of tubulin monomers.
8020	G-protein coupled photoreceptor activity	F	Combining with incidental electromagnetic radiation, particularly visible light, and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.
8021	synaptic vesicle	C	A secretory organelle, typically 50 nm in diameter, of presynaptic nerve terminals; accumulates in high concentrations of neurotransmitters and secretes these into the synaptic cleft by fusion with the 'active zone' of the presynaptic plasma membrane.
8022	protein C-terminus binding	F	Interacting selectively and non-covalently with a protein C-terminus, the end of any peptide chain at which the 1-carboxy function of a constituent amino acid is not attached in peptide linkage to another amino-acid residue.
8023	transcription elongation factor complex	C	Any protein complex that interacts with RNA polymerase II to increase (positive transcription elongation factor) or reduce (negative transcription elongation factor) the rate of transcription elongation.
8024	cyclin/CDK positive transcription elongation factor complex	C	A transcription elongation factor complex that facilitates the transition from abortive to productive elongation by phosphorylating the CTD domain of the large subunit of DNA-directed RNA polymerase II, holoenzyme. Contains a cyclin and a cyclin-dependent protein kinase catalytic subunit.
8026	ATP-dependent helicase activity	F	Catalysis of the reaction: ATP + H2O = ADP + phosphate, to drive the unwinding of a DNA or RNA helix.
8028	monocarboxylic acid transmembrane transporter activity	F	Enables the transfer of monocarboxylic acids from one side of the membrane to the other. A monocarboxylic acid is an organic acid with one COOH group.
8029	pentraxin receptor activity	F	Combining with a pentraxin and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
8030	neuronal pentraxin receptor activity	F	Combining with a neuronal pentraxin and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
8031	eclosion hormone activity	F	The action characteristic of eclosion hormone, a peptide hormone that, upon receptor binding, triggers the death of certain muscles and neurons during insect metamorphosis.
8033	tRNA processing	P	The process in which a pre-tRNA molecule is converted to a mature tRNA, ready for addition of an aminoacyl group.
8035	high-density lipoprotein particle binding	F	Interacting selectively and non-covalently with high-density lipoprotein particle, a lipoprotein particle with a high density (typically 1.063-1.21 g/ml) and a diameter of 5-10 nm that contains APOAs and may contain APOCs and APOE.
8036	diuretic hormone receptor activity	F	Combining with a diuretic hormone and transmitting the signal to initiate a change in cell activity.
8037	cell recognition	P	The process in which a cell in an organism interprets its surroundings.
8038	neuron recognition	P	The process in which a neuronal cell in a multicellular organism interprets its surroundings.
8039	synaptic target recognition	P	The process in which a neuronal cell in a multicellular organism interprets signals produced by potential target cells, with which it may form synapses.
8043	intracellular ferritin complex	C	A ferritin complex located in the cell. Intracellular ferritin complexes contain 24 subunits, in a mixture of L (light) chains and H (heavy) chains.
8045	motor neuron axon guidance	P	The process in which the migration of an axon growth cone of a motor neuron is directed to a specific target site in response to a combination of attractive and repulsive cues.
8046	axon guidance receptor activity	F	Combining with an extracellular messenger and transmitting the signal from one side of the membrane to the other to results in a change in cellular activity involved in axon guidance.
8047	enzyme activator activity	F	Binds to and increases the activity of an enzyme.
8048	calcium sensitive guanylate cyclase activator activity	F	Binds to and increases the activity of guanylate cyclase in response to a change in calcium ion concentration.
8049	male courtship behavior	P	The behavior of a male, for the purpose of attracting a sexual partner. An example of this process is found in Drosophila melanogaster.
8050	female courtship behavior	P	The behavior of a female, for the purpose of attracting a sexual partner.
8052	sensory organ boundary specification	P	The process in which boundaries between a sensory organ and the surrounding tissue are established and maintained.
8053	mitochondrial fusion	P	Merging of two or more mitochondria within a cell to form a single compartment.
8055	ocellus pigment biosynthetic process	P	The chemical reactions and pathways resulting in the formation of ocellus pigments, any general or particular coloring matter in living organisms, found or utilized in the ocellus, a minute simple eye found in many invertebrates.
8056	ocellus development	P	The process whose specific outcome is the progression of the ocellus over time, from its formation to the mature structure. The ocellus is a simple visual organ of insects.
8057	eye pigment granule organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of intracellular pigment storage granules in the eye.
8058	ocellus pigment granule organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of intracellular pigment storage granules in the ocellus.
8061	chitin binding	F	Interacting selectively and non-covalently with chitin, a linear polysaccharide consisting of beta-(1->4)-linked N-acetyl-D-glucosamine residues.
8062	eclosion rhythm	P	The timing of the emergence of the adult fly from its pupal case, which usually occurs at dawn.
8063	Toll signaling pathway	P	A series of molecular signals initiated by the binding of an extracellular ligand to the receptor Toll on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.
8064	regulation of actin polymerization or depolymerization	P	Any process that modulates the frequency, rate or extent of the assembly or disassembly of actin filaments by the addition or removal of actin monomers from a filament.
8065	establishment of blood-nerve barrier	P	The establishment of the barrier between the perineurium of peripheral nerves and the vascular endothelium of endoneurial capillaries. The perineurium acts as a diffusion barrier, but ion permeability at the blood-nerve barrier is still higher than at the blood-brain barrier.
8066	glutamate receptor activity	F	Combining with glutamate and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
8068	extracellular-glutamate-gated chloride channel activity	F	Enables the transmembrane transfer of a chloride ion by a channel that opens when extracellular glutamate has been bound by the channel complex or one of its constituent parts.
8069	dorsal/ventral axis specification, ovarian follicular epithelium	P	Polarization of the ovarian follicle cells along the dorsal/ventral axis. An example of this process is found in Drosophila melanogaster.
8070	maternal determination of dorsal/ventral axis, ovarian follicular epithelium, germ-line encoded	P	Polarization of the ovarian follicle cells along the dorsal-ventral axis by a gene product encoded by cells of the germ line.
8071	maternal determination of dorsal/ventral axis, ovarian follicular epithelium, soma encoded	P	Polarization of the ovarian follicle cells along the dorsal-ventral axis by a gene product encoded by somatic cells. An example of this process is found in Drosophila melanogaster.
8073	ornithine decarboxylase inhibitor activity	F	The stopping, prevention or reduction of the activity of the enzyme ornithine decarboxylase.
8074	guanylate cyclase complex, soluble	C	Complex that possesses guanylate cyclase activity and is not bound to a membrane.
8076	voltage-gated potassium channel complex	C	A protein complex that forms a transmembrane channel through which potassium ions may cross a cell membrane in response to changes in membrane potential.
8078	mesodermal cell migration	P	The orderly movement of mesodermal cells from one site to another.
8079	translation termination factor activity	F	Functions in the termination of translation.
8080	N-acetyltransferase activity	F	Catalysis of the transfer of an acetyl group to a nitrogen atom on the acceptor molecule.
8081	phosphoric diester hydrolase activity	F	Catalysis of the hydrolysis of a phosphodiester to give a phosphomonoester and a free hydroxyl group.
8083	growth factor activity	F	The function that stimulates a cell to grow or proliferate. Most growth factors have other actions besides the induction of cell growth or proliferation.
8084	imaginal disc growth factor receptor binding	F	Interacting selectively and non-covalently with an imaginal disc growth factor receptor.
8086	light-activated voltage-gated calcium channel activity	F	Enables the transmembrane transfer of a calcium ion by a voltage-gated channel that is activated in response to light. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.
8087	light-activated voltage-gated calcium channel complex	C	A protein complex that forms a transmembrane channel through which calcium ions may cross a cell membrane in response to changes in membrane potential generated in response to a light stimulus.
8088	axo-dendritic transport	P	The directed movement of organelles or molecules along microtubules in neuron projections.
8089	anterograde axonal transport	P	The directed movement of organelles or molecules along microtubules from the cell body toward the cell periphery in nerve cell axons.
8090	retrograde axonal transport	P	The directed movement of organelles or molecules along microtubules from the cell periphery toward the cell body in nerve cell axons.
8091	spectrin	C	Membrane associated dimeric protein (240 and 220 kDa) of erythrocytes. Forms a complex with ankyrin, actin and probably other components of the membrane cytoskeleton, so that there is a mesh of proteins underlying the plasma membrane, potentially restricting the lateral mobility of integral proteins.
8092	cytoskeletal protein binding	F	Interacting selectively and non-covalently with any protein component of any cytoskeleton (actin, microtubule, or intermediate filament cytoskeleton).
8093	cytoskeletal adaptor activity	F	The binding activity of a molecule that brings together a cytoskeletal protein and one or more other molecules, permitting them to function in a coordinated way.
8094	DNA-dependent ATPase activity	F	Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction requires the presence of single- or double-stranded DNA, and it drives another reaction.
8096	juvenile hormone epoxide hydrolase activity	F	Catalysis of the hydrolysis of the epoxide in a juvenile hormone to the corresponding diol.
8097	5S rRNA binding	F	Interacting selectively and non-covalently with 5S ribosomal RNA, the smallest RNA constituent of a ribosome.
8098	5S rRNA primary transcript binding	F	Interacting selectively and non-covalently with the unprocessed 5S ribosomal RNA transcript.
8101	decapentaplegic signaling pathway	P	A series of molecular signals initiated by the binding of decapentaplegic (dpp) to a receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.
8103	oocyte microtubule cytoskeleton polarization	P	Establishment and maintenance of a specific axis of polarity of the oocyte microtubule network. The axis is set so that the minus and plus ends of the microtubules of the mid stage oocyte are positioned along the anterior cortex and at the posterior pole, respectively. An example of this is found in Drosophila melanogaster.
8104	protein localization	P	Any process in which a protein is transported to, or maintained in, a specific location.
8105	asymmetric protein localization	P	Any process in which a protein is transported to, or maintained in, a specific location such that it is distributed asymmetrically.
8106	alcohol dehydrogenase (NADP+) activity	F	Catalysis of the reaction: an alcohol + NADP+ = an aldehyde + NADPH + H+.
8107	galactoside 2-alpha-L-fucosyltransferase activity	F	Catalysis of the reaction: GDP-L-fucose + beta-D-galactosyl-R = GDP + alpha-L-fucosyl-(1,2)-beta-D-galactosyl-R.
8108	UDP-glucose:hexose-1-phosphate uridylyltransferase activity	F	Catalysis of the reaction: alpha-D-galactose 1-phosphate + UDP-D-glucose = alpha-D-glucose 1-phosphate + UDP-D-galactose.
8109	N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity	F	Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + beta-D-galactosyl-1,4-N-acetyl-D-glucosaminyl-R = UDP + N-acetyl-beta-D-glucosaminyl-1,6-beta-D-galactosyl-1,4-N-acetyl-D-glucosaminyl-R.
8110	L-histidine:2-oxoglutarate aminotransferase activity	F	Catalysis of the reaction: 2-oxoglutarate + L-histidine = 3-(imidazol-5-yl)pyruvate + L-glutamate.
8111	alpha-methylacyl-CoA racemase activity	F	Catalysis of the reaction: (2S)-2-methylacyl-CoA = (2R)-2-methylacyl-CoA.
8112	nicotinamide N-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine(1+) + nicotinamide = 1-methylnicotinamide + S-adenosyl-L-homocysteine.
8113	peptide-methionine (S)-S-oxide reductase activity	F	Catalysis of the reactions: peptide-L-methionine + thioredoxin disulfide + H2O = peptide-L-methionine (S)-S-oxide + thioredoxin, and L-methionine + thioredoxin disulfide + H2O = L-methionine (S)-S-oxide + thioredoxin. Can act on oxidized methionine in peptide linkage with specificity for the S enantiomer. Thioredoxin disulfide is the oxidized form of thioredoxin.
8114	phosphogluconate 2-dehydrogenase activity	F	Catalysis of the reaction: 6-phospho-D-gluconate + NADP+ = 6-phospho-2-dehydro-D-gluconate + NADPH.
8115	sarcosine oxidase activity	F	Catalysis of the reaction: H(2)O + O(2) + sarcosine = formaldehyde + glycine + H(2)O(2).
8116	prostaglandin-I synthase activity	F	Catalysis of the reaction: prostaglandin H(2) = prostaglandin I(2).
8117	sphinganine-1-phosphate aldolase activity	F	Catalysis of the reaction: sphinganine 1-phosphate = phosphoethanolamine + palmitaldehyde.
8118	N-acetyllactosaminide alpha-2,3-sialyltransferase activity	F	Catalysis of the reaction: CMP-N-acetylneuraminate + beta-D-galactosyl-1,4-N-acetyl-D-glucosaminyl-glycoprotein = CMP + alpha-N-acetylneuraminyl-2,3-beta-D-galactosyl-1,4-N-acetyl-D-glucosaminyl-glycoprotein.
8119	thiopurine S-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + a thiopurine = S-adenosyl-L-homocysteine + a thiopurine S-methylether.
8120	ceramide glucosyltransferase activity	F	Catalysis of the reaction: UDP-glucose + N-acylsphingosine = UDP + D-glucosyl-N-acylsphingosine.
8121	ubiquinol-cytochrome-c reductase activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: CoQH2 + 2 ferricytochrome c = CoQ + 2 ferrocytochrome c + 2 H+.
8123	cholesterol 7-alpha-monooxygenase activity	F	Catalysis of the reaction: cholesterol + NADPH + H+ + O2 = 7-alpha-hydroxycholesterol + NADP+ + H2O.
8124	4-alpha-hydroxytetrahydrobiopterin dehydratase activity	F	Catalysis of the reaction: (6R)-6-(L-erythro-1,2-dihydroxypropyl)-5,6,7,8-tetrahydro-4a-hydroxypterin = (6R)-6-(L-erythro-1,2-dihydroxypropyl)-7,8-dihydro-6H-pterin + H(2)O.
8126	acetylesterase activity	F	Catalysis of the reaction: an acetic ester + H2O = an alcohol + acetate.
8127	quercetin 2,3-dioxygenase activity	F	Catalysis of the reaction: H(+) + O(2) + quercetin = 2-(3,4-dihydroxybenzoyloxy)-4,6-dihydroxybenzoate + CO.
8131	primary amine oxidase activity	F	Catalysis of the reaction: a primary amine + H2O + O2 = an aldehyde + NH3 + hydrogen peroxide.
8134	transcription factor binding	F	Interacting selectively and non-covalently with a transcription factor, any protein required to initiate or regulate transcription.
8135	translation factor activity, RNA binding	F	Functions during translation by interacting selectively and non-covalently with RNA during polypeptide synthesis at the ribosome.
8137	NADH dehydrogenase (ubiquinone) activity	F	Catalysis of the reaction: NADH + H+ + ubiquinone = NAD+ + ubiquinol.
8138	protein tyrosine/serine/threonine phosphatase activity	F	Catalysis of the reactions: protein serine + H2O = protein serine + phosphate; protein threonine phosphate + H2O = protein threonine + phosphate; and protein tyrosine phosphate + H2O = protein tyrosine + phosphate.
8139	nuclear localization sequence binding	F	Interacting selectively and non-covalently with a nuclear localization sequence, a specific peptide sequence that acts as a signal to localize the protein within the nucleus.
8140	cAMP response element binding protein binding	F	Interacting selectively and non-covalently with a cAMP response element binding protein (a CREB protein).
8142	oxysterol binding	F	Interacting selectively and non-covalently with oxysterol, an oxidized form of cholesterol.
8143	poly(A) binding	F	Interacting selectively and non-covalently with a sequence of adenylyl residues in an RNA molecule, such as the poly(A) tail, a sequence of adenylyl residues at the 3' end of eukaryotic mRNA.
8144	drug binding	F	Interacting selectively and non-covalently with a drug, any naturally occurring or synthetic substance, other than a nutrient, that, when administered or applied to an organism, affects the structure or functioning of the organism; in particular, any such substance used in the diagnosis, prevention, or treatment of disease.
8145	phenylalkylamine binding	F	Interacting selectively and non-covalently with phenylalkylamine or any of its derivatives.
8146	sulfotransferase activity	F	Catalysis of the transfer of a sulfate group from 3'-phosphoadenosine 5'-phosphosulfate to the hydroxyl group of an acceptor, producing the sulfated derivative and 3'-phosphoadenosine 5'-phosphate.
8147	structural constituent of bone	F	The action of a molecule that contributes to the structural integrity of bone.
8150	biological_process	P	Any process specifically pertinent to the functioning of integrated living units: cells, tissues, organs, and organisms. A process is a collection of molecular events with a defined beginning and end.
8152	metabolic process	P	The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and replication, and protein synthesis and degradation.
8153	para-aminobenzoic acid biosynthetic process	P	The chemical reactions and pathways resulting in the formation of para-aminobenzoic acid, an intermediate in the synthesis of folic acid, a compound which some organisms, e.g. prokaryotes, eukaryotic microbes, and plants, can synthesize de novo. Others, notably mammals, cannot. In yeast, it is present as a factor in the B complex of vitamins.
8154	actin polymerization or depolymerization	P	Assembly or disassembly of actin filaments by the addition or removal of actin monomers from a filament.
8156	negative regulation of DNA replication	P	Any process that stops, prevents, or reduces the frequency, rate or extent of DNA replication.
8157	protein phosphatase 1 binding	F	Interacting selectively and non-covalently with the enzyme protein phosphatase 1.
8158	hedgehog receptor activity	F	Combining with a member of the hedgehog protein family and transmitting the signal across the membrane to initiate a change in cell activity.
8160	protein tyrosine phosphatase activator activity	F	Increases the activity of a phosphatase, an enzyme which catalyzes of the removal of a phosphate group from a tyrosyl phenolic group of a protein.
8168	methyltransferase activity	F	Catalysis of the transfer of a methyl group to an acceptor molecule.
8169	C-methyltransferase activity	F	Catalysis of the transfer of a methyl group to the carbon atom of an acceptor molecule.
8170	N-methyltransferase activity	F	Catalysis of the transfer of a methyl group to the nitrogen atom of an acceptor molecule.
8171	O-methyltransferase activity	F	Catalysis of the transfer of a methyl group to the oxygen atom of an acceptor molecule.
8172	S-methyltransferase activity	F	Catalysis of the transfer of a methyl group to the sulfur atom of an acceptor molecule.
8173	RNA methyltransferase activity	F	Catalysis of the transfer of a methyl group from a donor to a nucleoside residue in an RNA molecule.
8174	mRNA methyltransferase activity	F	Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a nucleoside residue in an mRNA molecule.
8175	tRNA methyltransferase activity	F	Catalysis of the transfer of a methyl group from a donor to a nucleoside residue in a tRNA molecule.
8176	tRNA (guanine-N7-)-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing N7-methylguanine.
8177	succinate dehydrogenase (ubiquinone) activity	F	Catalysis of the reaction: succinate + ubiquinone = fumarate + ubiquinol.
8179	adenylate cyclase binding	F	Interacting selectively and non-covalently with the enzyme adenylate cyclase.
8180	COP9 signalosome	C	A protein complex that catalyzes the deneddylation of proteins, including the cullin component of SCF ubiquitin E3 ligase; deneddylation increases the activity of cullin family ubiquitin ligases. The signalosome is involved in many regulatory process, including some which control development, in many species; also regulates photomorphogenesis in plants; in many species its subunits are highly similar to those of the proteasome.
8184	glycogen phosphorylase activity	F	Catalysis of the reaction: glycogen + phosphate = maltodextrin + alpha-D-glucose 1-phosphate.
8186	RNA-dependent ATPase activity	F	Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction requires the presence of RNA, and it drives another reaction.
8187	poly-pyrimidine tract binding	F	Interacting selectively and non-covalently with any stretch of pyrimidines (cytosine or uracil) in an RNA molecule.
8188	neuropeptide receptor activity	F	Combining with a neuropeptide to initiate a change in cell activity.
8190	eukaryotic initiation factor 4E binding	F	Interacting selectively and non-covalently with eukaryotic initiation factor 4E, a polypeptide factor involved in the initiation of ribosome-mediated translation.
8191	metalloendopeptidase inhibitor activity	F	Stops, prevents or reduces the activity of metalloendopeptidases, enzymes that catalyze the hydrolysis of nonterminal peptide bonds in a polypeptide chain and contain a chelated metal ion at their active sites which is essential to their catalytic activity.
8192	RNA guanylyltransferase activity	F	Catalysis of the posttranscriptional addition of a guanyl residue to the 5' end of an RNA molecule.
8193	tRNA guanylyltransferase activity	F	Catalysis of the posttranscriptional addition of a guanyl residue to the 5' end of a tRNA molecule; observed for His tRNAs.
8194	UDP-glycosyltransferase activity	F	Catalysis of the transfer of a glycosyl group from a UDP-sugar to a small hydrophobic molecule.
8195	phosphatidate phosphatase activity	F	Catalysis of the reaction: a 1,2-diacylglycerol 3-phosphate + H2O = a 1,2-diacyl-sn-glycerol + phosphate.
8196	vitellogenin receptor activity	F	Receiving vitellogenin, and delivering vitellogenin into the cell via endocytosis.
8198	ferrous iron binding	F	Interacting selectively and non-covalently with ferrous iron, Fe(II).
8199	ferric iron binding	F	Interacting selectively and non-covalently with ferric iron, Fe(III).
8200	ion channel inhibitor activity	F	Stops, prevents, or reduces the activity of an ion channel.
8201	heparin binding	F	Interacting selectively and non-covalently with heparin, any member of a group of glycosaminoglycans found mainly as an intracellular component of mast cells and which consist predominantly of alternating alpha-(1->4)-linked D-galactose and N-acetyl-D-glucosamine-6-sulfate residues.
8202	steroid metabolic process	P	The chemical reactions and pathways involving steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus.
8203	cholesterol metabolic process	P	The chemical reactions and pathways involving cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones. It is a component of the plasma membrane lipid bilayer and of plasma lipoproteins and can be found in all animal tissues.
8204	ergosterol metabolic process	P	The chemical reactions and pathways involving ergosterol, (22E)-ergosta-5,7,22-trien-3-beta-ol, a sterol found in ergot, yeast and moulds. It is the most important of the D provitamins and is converted to vitamin D2 on irradiation with UV light.
8205	ecdysone metabolic process	P	The chemical reactions and pathways involving ecdysone, (22R)-2-beta,3-beta,14,22,25-pentahydroxycholest-7-en-6-one, an ecdysteroid found in insects. It is the inactive prohormone of the moulting hormone ecdysterone and may have intrinsic hormonal activity at other stages of insect development.
8206	bile acid metabolic process	P	The chemical reactions and pathways involving bile acids, any of a group of steroid carboxylic acids occurring in bile, where they are present as the sodium salts of their amides with glycine or taurine.
8207	C21-steroid hormone metabolic process	P	The chemical reactions and pathways involving C21-steroid hormones, steroid compounds containing 21 carbons which function as hormones.
8208	C21-steroid hormone catabolic process	P	The chemical reactions and pathways resulting in the breakdown of C21-steroid hormones, steroid compounds containing 21 carbons which function as hormones.
8209	androgen metabolic process	P	The chemical reactions and pathways involving androgens, C19 steroid hormones that can stimulate the development of male sexual characteristics.
8210	estrogen metabolic process	P	The chemical reactions and pathways involving estrogens, C18 steroid hormones that can stimulate the development of female sexual characteristics. Also found in plants.
8211	glucocorticoid metabolic process	P	The chemical reactions and pathways involving glucocorticoids, hormonal C21 corticosteroids synthesized from cholesterol. Glucocorticoids act primarily on carbohydrate and protein metabolism, and have anti-inflammatory effects.
8212	mineralocorticoid metabolic process	P	The chemical reactions and pathways involving mineralocorticoids, hormonal C21 corticosteroids synthesized from cholesterol. Mineralocorticoids act primarily on water and electrolyte balance.
8213	protein alkylation	P	The addition of an alkyl group to a protein amino acid. An alkyl group is any group derived from an alkane by removal of one hydrogen atom.
8214	protein dealkylation	P	The removal of an alkyl group from a protein amino acid. An alkyl group is any group derived from an alkane by removal of one hydrogen atom.
8215	spermine metabolic process	P	The chemical reactions and pathways involving spermine, a polybasic amine found in human sperm, in ribosomes and in some viruses, which is involved in nucleic acid packaging. Synthesis is regulated by ornithine decarboxylase which plays a key role in control of DNA replication.
8216	spermidine metabolic process	P	The chemical reactions and pathways involving spermidine, N-(3-aminopropyl)-1,4-diaminobutane.
8217	regulation of blood pressure	P	Any process that modulates the force with which blood travels through the circulatory system. The process is controlled by a balance of processes that increase pressure and decrease pressure.
8218	bioluminescence	P	The production of light by certain enzyme-catalyzed reactions in cells.
8219	cell death	P	Any biological process that results in permanent cessation of all vital functions of a cell. A cell should be considered dead when any one of the following molecular or morphological criteria is met: (1) the cell has lost the integrity of its plasma membrane; (2) the cell, including its nucleus, has undergone complete fragmentation into discrete bodies (frequently referred to as apoptotic bodies). The cell corpse (or its fragments) may be engulfed by an adjacent cell in vivo, but engulfment of whole cells should not be considered a strict criteria to define cell death as, under some circumstances, live engulfed cells can be released from phagosomes (see PMID:18045538).
8226	tyramine receptor activity	F	Combining with the biogenic amine tyramine to initiate a change in cell activity. Tyramine is a sympathomimetic amine derived from tyrosine with an action resembling that of epinephrine.
8227	G-protein coupled amine receptor activity	F	Combining with an extracellular amine and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.
8228	opsonization	P	The process in which a microorganism (or other particulate material) is rendered more susceptible to phagocytosis by coating with an opsonin, a blood serum protein such as a complement component or antibody.
8230	ecdysone receptor holocomplex	C	A heterodimeric complex containing the products of the insect genes Ecdysone receptor (EcR) and ultraspiracle (usp). Binding of ecdysone promotes association between the two subunits, and the receptor complex then initiates molting and metamorphosis by binding DNA and regulating the transcription of target genes.
8231	repressor ecdysone receptor complex	C	A protein complex consisting of a heterodimer of Ecdysone receptor (EcR) and ultraspiracle (usp) plus an associated corepressor such as SMRTER, which represses transcription of target genes.
8232	activator ecdysone receptor complex	C	A protein complex consisting of a heterodimer of Ecdysone receptor (EcR) and ultraspiracle (usp) bound to the ligand ecdysone, which activates transcription of target genes.
8233	peptidase activity	F	Catalysis of the hydrolysis of a peptide bond. A peptide bond is a covalent bond formed when the carbon atom from the carboxyl group of one amino acid shares electrons with the nitrogen atom from the amino group of a second amino acid.
8234	cysteine-type peptidase activity	F	Catalysis of the hydrolysis of peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile.
8235	metalloexopeptidase activity	F	Catalysis of the hydrolysis of a peptide bond not more than three residues from the N- or C-terminus of a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions.
8236	serine-type peptidase activity	F	Catalysis of the hydrolysis of peptide bonds in a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine).
8237	metallopeptidase activity	F	Catalysis of the hydrolysis of peptide bonds by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions.
8238	exopeptidase activity	F	Catalysis of the hydrolysis of a peptide bond not more than three residues from the N- or C-terminus of a polypeptide chain, in a reaction that requires a free N-terminal amino group, C-terminal carboxyl group or both.
8239	dipeptidyl-peptidase activity	F	Catalysis of the hydrolysis of N-terminal dipeptides from a polypeptide chain.
8240	tripeptidyl-peptidase activity	F	Catalysis of the release of an N-terminal tripeptide from a polypeptide.
8241	peptidyl-dipeptidase activity	F	Catalysis of the release of C-terminal dipeptides from a polypeptide chain.
8242	omega peptidase activity	F	Catalysis of the removal of terminal peptide residues that are substituted, cyclized or linked by isopeptide bonds (peptide linkages other than those of alpha-carboxyl to alpha-amino groups).
8247	1-alkyl-2-acetylglycerophosphocholine esterase complex	C	An enzyme complex composed of two catalytic alpha subunits, which form a catalytic dimer, and a non-catalytic, regulatory beta subunit; the catalytic dimer may be an alpha1/alpha1 or alpha2/alpha2 homodimer, or an alpha1/alpha2 heterodimer. Modulates the action of platelet-activating factor (PAF).
8250	oligosaccharyltransferase complex	C	A protein complex that is found in the endoplasmic reticulum membrane of eukaryotes and transfers lipid-linked oligosaccharide precursor to asparagine residues on nascent proteins. In yeast, the complex includes at least nine different subunits, whereas in mammalian cells at least three different forms of the complex have been detected.
8251	tRNA-specific adenosine deaminase activity	F	Catalysis of the reaction: adenosine + H2O = inosine + NH3, in a tRNA molecule.
8252	nucleotidase activity	F	Catalysis of the reaction: a nucleotide + H2O = a nucleoside + phosphate.
8253	5'-nucleotidase activity	F	Catalysis of the reaction: a 5'-ribonucleotide + H2O = a ribonucleoside + phosphate.
8254	3'-nucleotidase activity	F	Catalysis of the reaction: a 3'-ribonucleotide + H2O = a ribonucleoside + phosphate.
8255	ecdysis-triggering hormone activity	F	The action characteristic of ecdysis-triggering hormone, a peptide hormone that, upon receptor binding, initiates pre-ecdysis and ecdysis (i.e. cuticle shedding) through direct action on the central nervous system.
8256	protein histidine pros-kinase activity	F	Catalysis of the reaction: ATP + protein L-histidine = ADP + protein N(pi)-phospho-L-histidine.
8257	protein histidine tele-kinase activity	F	Catalysis of the reaction: ATP + protein L-histidine = ADP + protein N(tau)-phospho-L-histidine.
8258	head involution	P	Movement of the anterior ectoderm to the interior of the embryo.
8260	3-oxoacid CoA-transferase activity	F	Catalysis of the reaction: succinyl-CoA + a 3-oxo acid = succinate + a 3-oxo-acyl-CoA.
8261	allatostatin receptor activity	F	Combining with allatostatin to initiate a change in cell activity.
8263	pyrimidine-specific mismatch base pair DNA N-glycosylase activity	F	Catalysis of the removal of mismatched pyrimidine bases in DNA. Enzymes with this activity recognize and remove pyrimidines present in mismatches by cleaving the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar. The reaction releases a free base and leaves an apyrimidinic (AP) site.
8265	Mo-molybdopterin cofactor sulfurase activity	F	Catalysis of the sulfurylation of the desulfo form of molybdenum cofactor (MoCo), a cofactor required for the activity of some enzymes, such as aldehyde oxidase.
8266	poly(U) RNA binding	F	Interacting selectively and non-covalently with a sequence of uracil residues in an RNA molecule.
8267	poly-glutamine tract binding	F	Interacting selectively and non-covalently with a polyglutamine tract, i.e. a series of consecutive glutamine residues, in a protein.
8269	JAK pathway signal transduction adaptor activity	F	The binding activity of a molecule that brings together two molecules of the JAK signal transduction pathway, permitting them to function in a coordinated way.
8270	zinc ion binding	F	Interacting selectively and non-covalently with zinc (Zn) ions.
8271	secondary active sulfate transmembrane transporter activity	F	Catalysis of the secondary active transfer of sulfate from one side of the membrane to the other. Secondary active transport is catalysis of the transfer of a solute from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Chemiosmotic sources of energy include uniport, symport or antiport.
8272	sulfate transport	P	The directed movement of sulfate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
8273	calcium, potassium:sodium antiporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Ca2+(in) + K+(in) + Na+(out) = Ca2+(out) + K+(out) + Na+(in).
8274	gamma-tubulin ring complex	C	A multiprotein complex composed of gamma-tubulin and other non-tubulin proteins that forms a flexible open ring structure thought to be the unit of nucleation at the minus end of a microtubule.
8275	gamma-tubulin small complex	C	A complex usually comprising two gamma-tubulin molecules and two conserved non-tubulin proteins. Some gamma-tubulin small complexes are thought to be the repeating unit making up the core of the gamma-tubulin ring complex.
8276	protein methyltransferase activity	F	Catalysis of the transfer of a methyl group (CH3-) to a protein.
8277	regulation of G-protein coupled receptor protein signaling pathway	P	Any process that modulates the frequency, rate or extent of G-protein coupled receptor protein signaling pathway activity.
8278	cohesin complex	C	A protein complex that is required for sister chromatid cohesion in eukaryotes. The cohesin complex forms a molecular ring complex, and is composed of structural maintenance of chromosomes (SMC) and kleisin proteins. For example, in yeast, the complex is composed of the SMC proteins Smc1p and Smc3p, and the kleisin protein Scc1p. In vertebrates, the complex is composed of the SMC1 (SMC1A or SMC1B) and SMC3 heterodimer attached via their hinge domains to a kleisin (RAD21, REC8 or RAD21L) which links them, and one STAG protein (STAG1, STAG2 or STAG3).
8281	sulfonylurea receptor activity	F	Combining with sulfonylurea, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
8282	ATP-sensitive potassium channel complex	C	A protein complex that comprises four pore-forming (Kir6.x) and four regulatory sulphonylurea receptor (SURx) subunits and forms a transmembrane channel through which ions may pass. The opening and closing of the channel is regulated by ATP: binding of ATP to the Kir6.x subunit inhibits channel activity, whereas binding of Mg2+-complexed ATP or ADP to the SURx subunit stimulates channel activity.
8283	cell proliferation	P	The multiplication or reproduction of cells, resulting in the expansion of a cell population.
8284	positive regulation of cell proliferation	P	Any process that activates or increases the rate or extent of cell proliferation.
8285	negative regulation of cell proliferation	P	Any process that stops, prevents or reduces the rate or extent of cell proliferation.
8286	insulin receptor signaling pathway	P	The series of molecular signals generated as a consequence of the insulin receptor binding to insulin.
8287	protein serine/threonine phosphatase complex	C	A complex, normally consisting of a catalytic and a regulatory subunit, which catalyzes the removal of a phosphate group from a serine or threonine residue of a protein.
8288	boss receptor activity	F	Combining with a protein bride of sevenless (boss) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: ATP + a protein-L-tyrosine = ADP + a protein-L-tyrosine phosphate.
8289	lipid binding	F	Interacting selectively and non-covalently with a lipid.
8290	F-actin capping protein complex	C	A heterodimer consisting of alpha and beta subunits that binds to and caps the barbed ends of actin filaments, thereby regulating the polymerization of actin monomers but not severing actin filaments.
8291	acetylcholine metabolic process	P	The chemical reactions and pathways involving acetylcholine, the acetic acid ester of the organic base choline. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues.
8292	acetylcholine biosynthetic process	P	The chemical reactions and pathways resulting in the formation of acetylcholine, the acetic acid ester of the organic base choline.
8293	torso signaling pathway	P	A series of molecular signals initiated by the binding of an extracellular ligand to torso (a receptor tyrosine kinase) on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.
8294	calcium- and calmodulin-responsive adenylate cyclase activity	F	Catalysis of the reaction: ATP = 3',5'-cyclic AMP + diphosphate, stimulated by calcium-bound calmodulin.
8295	spermidine biosynthetic process	P	The chemical reactions and pathways resulting in the formation of spermidine, N-(3-aminopropyl)-1,4-diaminobutane.
8296	3'-5'-exodeoxyribonuclease activity	F	Catalysis of the sequential cleavage of mononucleotides from a free 3' terminus of a DNA molecule.
8297	single-stranded DNA exodeoxyribonuclease activity	F	Catalysis of the sequential cleavage of mononucleotides from a free 5' or 3' terminus of a single-stranded DNA molecule.
8298	intracellular mRNA localization	P	Any process in which mRNA is transported to, or maintained in, a specific location within the cell.
8299	isoprenoid biosynthetic process	P	The chemical reactions and pathways resulting in the formation of any isoprenoid compound, isoprene (2-methylbuta-1,3-diene) or compounds containing or derived from linked isoprene (3-methyl-2-butenylene) residues.
8300	isoprenoid catabolic process	P	The chemical reactions and pathways resulting in the breakdown of any isoprenoid compound, isoprene (2-methylbuta-1,3-diene) or compounds containing or derived from linked isoprene (3-methyl-2-butenylene) residues.
8301	DNA binding, bending	F	The activity of binding selectively and non-covalently to and distorting the original structure of DNA, typically a straight helix, into a bend, or increasing the bend if the original structure was intrinsically bent due to its sequence.
8302	female germline ring canal formation, actin assembly	P	Recruitment and organization of actin filaments in female germline ring canals.
8303	caspase complex	C	A protein complex that is located in the cytosol and contains one or more cysteine-type endopeptidases (also called caspases), which give the complex a peptidase activity with specificity for the hydrolysis of aspartyl bonds. These complexes may be involved e.g. in apoptotic or inflammation processes.
8305	integrin complex	C	A protein complex that is composed of one alpha subunit and one beta subunit, both of which are members of the integrin superfamily of cell adhesion receptors; the complex spans the plasma membrane and binds to extracellular matrix ligands, cell-surface ligands, and soluble ligands.
8306	associative learning	P	Learning by associating a stimulus (the cause) with a particular outcome (the effect).
8307	structural constituent of muscle	F	The action of a molecule that contributes to the structural integrity of a muscle fiber.
8308	voltage-gated anion channel activity	F	Enables the transmembrane transfer of an anion by a voltage-gated channel. An anion is a negatively charged ion. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.
8309	double-stranded DNA exodeoxyribonuclease activity	F	Catalysis of the sequential cleavage of mononucleotides from a free 5' or 3' terminus of a double-stranded DNA molecule.
8310	single-stranded DNA 3'-5' exodeoxyribonuclease activity	F	Catalysis of the sequential cleavage of mononucleotides from a free 3' terminus of a single-stranded DNA molecule.
8311	double-stranded DNA 3'-5' exodeoxyribonuclease activity	F	Catalysis of the sequential cleavage of mononucleotides from a free 3' terminus of a double-stranded DNA molecule.
8312	7S RNA binding	F	Interacting selectively and non-covalently with 7S RNA, the RNA component of the signal recognition particle (SRP).
8313	gurken-activated receptor activity	F	Combining with the ligand Gurken to initiate a change in cell activity.
8314	gurken signaling pathway	P	The series of molecular signals generated as a consequence of an epidermal growth factor receptor binding to the ligand Gurken.
8315	meiotic G2/MI transition	P	The cell cycle process in which a cell progresses from meiotic prophase to metaphase I.
8316	structural constituent of vitelline membrane	F	The action of a molecule that contributes to the structural integrity of the vitelline membrane of an egg. An example of this is found in Drosophila melanogaster.
8317	gurken receptor binding	F	Interacting selectively and non-covalently with the gurken growth factor receptor.
8318	protein prenyltransferase activity	F	Catalysis of the covalent addition of an isoprenoid group such as a farnesyl or geranylgeranyl group via thioether linkages to a cysteine residue in a protein.
8320	protein transmembrane transporter activity	F	Enables the transfer of a protein from one side of a membrane to the other.
8321	Ral guanyl-nucleotide exchange factor activity	F	Stimulates the exchange of guanyl nucleotides associated with a GTPase of the Ral family. Under normal cellular physiological conditions, the concentration of GTP is higher than that of GDP, favoring the replacement of GDP by GTP in association with the GTPase.
8324	cation transmembrane transporter activity	F	Enables the transfer of cation from one side of the membrane to the other.
8327	methyl-CpG binding	F	Interacting selectively and non-covalently with a methylated cytosine/guanine dinucleotide.
8328	ionotropic glutamate receptor complex	C	A multimeric assembly of four or five subunits which form a structure with an extracellular N-terminus and a large loop that together form the ligand binding domain. The C-terminus is intracellular. The ionotropic glutamate receptor complex itself acts as a ligand-gated ion channel; on binding glutamate, charged ions pass through a channel in the center of the receptor complex.
8329	signaling pattern recognition receptor activity	F	Combining with a pathogen-associated molecular pattern (PAMP), a structure conserved among microbial species, or damage-associated molecular pattern (DAMP), an endogenous molecule released from damaged cells), and transmitting a signal to initiate a change in cell activity.
8330	protein tyrosine/threonine phosphatase activity	F	Catalysis of the reactions: protein threonine phosphate + H2O = protein threonine + phosphate; and protein tyrosine phosphate + H2O = protein tyrosine + phosphate.
8331	high voltage-gated calcium channel activity	F	Enables the transmembrane transfer of a calcium ion by a high voltage-gated channel. A high voltage-gated channel is a channel whose open state is dependent on high voltage across the membrane in which it is embedded.
8332	low voltage-gated calcium channel activity	F	Enables the transmembrane transfer of a calcium ion by a low voltage-gated channel. A low voltage-gated channel is a channel whose open state is dependent on low voltage across the membrane in which it is embedded.
8333	endosome to lysosome transport	P	The directed movement of substances from endosomes to lysosomes.
8334	histone mRNA metabolic process	P	The chemical reactions and pathways involving an mRNA encoding a histone.
8335	female germline ring canal stabilization	P	Maintenance of the structural integrity of the ring canals connecting the female germline cyst.
8336	gamma-butyrobetaine dioxygenase activity	F	Catalysis of the reaction: 2-oxoglutarate + 4-(trimethylammonio)butanoate + O(2) = carnitine + CO(2) + succinate.
8340	determination of adult lifespan	P	The control of viability and duration in the adult phase of the life-cycle.
8343	adult feeding behavior	P	Feeding behavior in a fully developed and mature organism.
8344	adult locomotory behavior	P	Locomotory behavior in a fully developed and mature organism.
8345	larval locomotory behavior	P	Locomotory behavior in a larval (immature) organism.
8346	larval walking behavior	P	The behavior of a larval organism relating to the progression of that organism along the ground by the process of lifting and setting down each leg.
8347	glial cell migration	P	The orderly movement of a glial cell, non-neuronal cells that provide support and nutrition, maintain homeostasis, form myelin, and participate in signal transmission in the nervous system.
8348	negative regulation of antimicrobial humoral response	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of an antimicrobial humoral response.
8349	MAP kinase kinase kinase kinase activity	F	Catalysis of the phosphorylation of serine and threonine residues in a mitogen-activated protein kinase kinase kinase (MAPKKK), resulting in activation of MAPKKK. MAPKKK signaling pathways relay, amplify and integrate signals from the plasma membrane to the nucleus in response to a diverse range of extracellular stimuli.
8352	katanin complex	C	A complex possessing an activity that couples ATP hydrolysis to the severing of microtubules; usually a heterodimer comprising a catalytic subunit (often 60kDa) and a regulatory subunit (often 80 kDa).
8353	RNA polymerase II carboxy-terminal domain kinase activity	F	Catalysis of the reaction: ATP + (DNA-directed RNA polymerase II) = ADP + phospho-(DNA-directed RNA polymerase II); phosphorylation occurs on residues in the carboxy-terminal domain (CTD) repeats.
8354	germ cell migration	P	The orderly movement of a cell specialized to produce haploid gametes through the embryo from its site of production to the place where the gonads will form.
8355	olfactory learning	P	Any process in an organism in which a relatively long-lasting adaptive behavioral change occurs in response to (repeated) exposure to an olfactory cue.
8356	asymmetric cell division	P	The asymmetric division of cells to produce two daughter cells with different developmental potentials. It is of fundamental significance for the generation of cell diversity.
8358	maternal determination of anterior/posterior axis, embryo	P	The specification of the anterior/posterior axis of the embryo by gradients of maternally-transcribed gene products; exemplified in insects by the morphogens, bicoid and nanos.
8359	regulation of bicoid mRNA localization	P	Any process that modulates the frequency, rate or extent of the process in which bicoid mRNA is transported to, or maintained in, a specific location.
8360	regulation of cell shape	P	Any process that modulates the surface configuration of a cell.
8361	regulation of cell size	P	Any process that modulates the size of a cell.
8362	chitin-based embryonic cuticle biosynthetic process	P	Synthesis, including the chemical reactions and pathways resulting in the formation of chitin and other components, and deposition of a chitin-based embryonic cuticle by the underlying epidermal epithelium. This tough, waterproof cuticle layer is essential to provide structural integrity of the larval body. An example of this is found in Drosophila melanogaster.
8363	larval chitin-based cuticle development	P	Synthesis and deposition of a chitin-based larval cuticle. The insect larval cuticle is a secretion from epidermal cells that is shed at each molt. An example of this is found in Drosophila melanogaster.
8364	pupal chitin-based cuticle development	P	Synthesis and deposition of a chitin-based pupal cuticle. At the end of the prepupal period the insect is covered by the pupal cuticle which continues to be elaborated into the pupal period. An example of this is found in Drosophila melanogaster.
8365	adult chitin-based cuticle development	P	Synthesis and deposition of the chitin-based cuticle of adults following the apolysis of the pupal cuticle. The adult insect cuticle contains cuticullin, a protein epicuticle and a lamellate procuticle. An example of this process is adult chitin-based cuticle development in Drosophila melanogaster.
8366	axon ensheathment	P	Any process in which the axon of a neuron is insulated, and that insulation maintained, thereby preventing dispersion of the electrical signal.
8373	sialyltransferase activity	F	Catalysis of the transfer of sialic acid to an acceptor molecule, typically the terminal portions of the sialylated glycolipids (gangliosides) or to the N- or O-linked sugar chains of glycoproteins.
8374	O-acyltransferase activity	F	Catalysis of the transfer of an acyl group to an oxygen atom on the acceptor molecule.
8375	acetylglucosaminyltransferase activity	F	Catalysis of the transfer of an N-acetylglucosaminyl residue from UDP-N-acetyl-glucosamine to a sugar.
8376	acetylgalactosaminyltransferase activity	F	Catalysis of the transfer of an N-acetylgalactosaminyl residue from UDP-N-acetyl-galactosamine to an oligosaccharide.
8377	light-induced release of internally sequestered calcium ion	P	The process in which the detection of light triggers the release of internally sequestered calcium ions.
8378	galactosyltransferase activity	F	Catalysis of the transfer of a galactosyl group to an acceptor molecule, typically another carbohydrate or a lipid.
8379	thioredoxin peroxidase activity	F	Catalysis of the reaction: thioredoxin + hydrogen peroxide = thioredoxin disulfide + H2O.
8380	RNA splicing	P	The process of removing sections of the primary RNA transcript to remove sequences not present in the mature form of the RNA and joining the remaining sections to form the mature form of the RNA.
8381	mechanically-gated ion channel activity	F	Enables the transmembrane transfer of an ion by a channel that opens in response to a mechanical stress.
8384	IkappaB kinase activity	F	Catalysis of the reaction: ATP + IkappaB protein = ADP + IkappaB phosphoprotein.
8385	IkappaB kinase complex	C	A trimeric protein complex that phosphorylates inhibitory-kappaB (I-kappaB) proteins. The complex is composed of two kinase subunits (alpha and beta) and a regulatory gamma subunit (also called NEMO). In a resting state, NF-kappaB dimers are bound to inhibitory IKB proteins, sequestering NF-kappaB in the cytoplasm. Phosphorylation of I-kappaB targets I-kappaB for ubiquitination and proteasomal degradation, thus releasing the NF-kappaB dimers, which can translocate to the nucleus to bind DNA and regulate transcription.
8386	cholesterol monooxygenase (side-chain-cleaving) activity	F	Catalysis of the reaction: cholesterol + reduced adrenal ferredoxin + O2 = pregnenolone + 4-methylpentanal + oxidized adrenal ferredoxin + H2O.
8387	steroid 7-alpha-hydroxylase activity	F	Catalysis of the reaction: a steroid + donor-H2 + O2 = 7-alpha-hydroxysteroid + H2O.
8388	testosterone 15-alpha-hydroxylase activity	F	Catalysis of the reaction: testosterone + donor-H2 + O2 = 15-alpha-hydroxytestosterone + H2O.
8389	coumarin 7-hydroxylase activity	F	Catalysis of the reaction: coumarin + O2 + NADPH + H+ = hydroxycoumarin + H2O + NADP+.
8390	testosterone 16-alpha-hydroxylase activity	F	Catalysis of the reaction: testosterone + donor-H2 + O2 = 16-alpha-hydroxytestosterone + H2O.
8391	arachidonic acid monooxygenase activity	F	Catalysis of the incorporation of one atom from molecular oxygen into arachidonic acid and the reduction of the other atom of oxygen to water.
8392	arachidonic acid epoxygenase activity	F	Catalysis of an NADPH- and oxygen-dependent reaction that converts arachidonic acid to a cis-epoxyeicosatrienoic acid.
8395	steroid hydroxylase activity	F	Catalysis of the formation of a hydroxyl group on a steroid by incorporation of oxygen from O2.
8396	oxysterol 7-alpha-hydroxylase activity	F	Catalysis of the reaction: an oxysterol + NADPH + O2 = 7-alpha-hydroxylated oxysterol + NADP+ + H2O.
8397	sterol 12-alpha-hydroxylase activity	F	Catalysis of the reaction: a steroid + donor-H2 + O2 = 12-alpha-hydroxysteroid + H2O.
8398	sterol 14-demethylase activity	F	Catalysis of the reaction: obtusifoliol + 3 O2 + 3 NADPH + 3 H+ = 4-alpha-methyl-5-alpha-ergosta-8,14,24(28)-trien-3-beta-ol + formate + 3 NADP+ + 3 H2O.
8399	naphthalene hydroxylase activity	F	Catalysis of the conversion of naphthalene to naphthalene 1,2-oxide.
8401	retinoic acid 4-hydroxylase activity	F	Catalysis of the conversion of retinoic acid to 4-hydroxy-retinoic acid.
8403	25-hydroxycholecalciferol-24-hydroxylase activity	F	Catalysis of the hydroxylation of C-24 of 25-hydroxycholecalciferol (25-hydroxyvitamin D3) to form 24(R),25-dihydroxycholecalciferol.
8404	arachidonic acid 14,15-epoxygenase activity	F	Catalysis of an NADPH- and oxygen-dependent reaction that converts arachidonic acid to cis-14,15-epoxyeicosatrienoic acid.
8405	arachidonic acid 11,12-epoxygenase activity	F	Catalysis of an NADPH- and oxygen-dependent reaction that converts arachidonic acid to cis-11,12-epoxyeicosatrienoic acid.
8406	gonad development	P	The process whose specific outcome is the progression of the gonad over time, from its formation to the mature structure. The gonad is an animal organ that produces gametes; in some species it also produces hormones.
8407	chaeta morphogenesis	P	The process in which the anatomical structures of the chaeta are generated and organized. A chaeta is a sensory multicellular cuticular outgrowth of a specifically differentiated cell.
8408	3'-5' exonuclease activity	F	Catalysis of the hydrolysis of ester linkages within nucleic acids by removing nucleotide residues from the 3' end.
8409	5'-3' exonuclease activity	F	Catalysis of the hydrolysis of ester linkages within nucleic acids by removing nucleotide residues from the 5' end.
8410	CoA-transferase activity	F	Catalysis of the transfer of a coenzyme A (CoA) group from one compound (donor) to another (acceptor).
8411	4-hydroxybutyrate CoA-transferase activity	F	Catalysis of the transfer of a coenzyme A (CoA) group to 4-hydroxybutyrate.
8412	4-hydroxybenzoate octaprenyltransferase activity	F	Catalysis of the reaction: farnesylfarnesylgeranyl diphosphate + p-hydroxybenzoate = 3-octaprenyl-4-hydroxybenzoate + diphosphate.
8413	8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity	F	Catalysis of the reaction: 8-oxo-7,8-dihydroguanosine triphosphate = 8-oxo-7,8-dihydroguanosine phosphate + diphosphate. 8-oxo-7,8-dihydroguanosine triphosphate (8-oxo-GTP) is the oxidised form of the free guanine nucleotide and can act as a potent mutagenic substrate for transcription.
8414	CDP-alcohol phosphotransferase activity	F	Catalysis of the transfer of a CDP-alcohol group from one compound to another.
8417	fucosyltransferase activity	F	Catalysis of the transfer of a fucosyl group to an acceptor molecule, typically another carbohydrate or a lipid.
8418	protein-N-terminal asparagine amidohydrolase activity	F	Catalysis of the reaction: protein-L-asparagine + H2O = protein-L-aspartate + NH3. This reaction is the deamidation of an N-terminal asparagine residue in a peptide or protein.
8419	RNA lariat debranching enzyme activity	F	Catalysis of the hydrolysis of branched RNA structures that contain vicinal 2'-5'- and 3'-5'-phosphodiester bonds at a branch point nucleotide.
8420	CTD phosphatase activity	F	Catalysis of the reaction: phospho-(DNA-directed RNA polymerase) + H2O = (DNA-directed RNA polymerase) + phosphate.
8421	long-chain fatty-acyl-glutamate deacylase activity	F	Catalysis of the reaction: N-long-chain-fatty-acyl-L-glutamate + H2O = a fatty acid anion + L-glutamate.
8422	beta-glucosidase activity	F	Catalysis of the hydrolysis of terminal, non-reducing beta-D-glucose residues with release of beta-D-glucose.
8424	glycoprotein 6-alpha-L-fucosyltransferase activity	F	Catalysis of the reaction: N(4)-{N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->6)]-beta-D-mannosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-N-acetyl-beta-D-glucosaminyl}-L-asparagine + GDP-L-fucose = N(4)-{N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->6)]-beta-D-mannosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-[alpha-L-fucosyl-(1->6)]-N-acetyl-beta-D-glucosaminyl}asparagine + GDP + H(+).
8425	2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity	F	Catalysis of the reaction: 2-polyprenyl-6-methoxy-1,4-benzoquinone + S-adenosyl-L-methionine = 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinone + S-adenosyl-L-homocysteine.
8426	protein kinase C inhibitor activity	F	Stops, prevents or reduces the activity of protein kinase C, an enzyme which phosphorylates a protein.
8427	calcium-dependent protein kinase inhibitor activity	F	Stops, prevents or reduces the activity of a calcium-dependent protein kinase.
8428	ribonuclease inhibitor activity	F	Stops, prevents or reduces the activity of a ribonuclease, any enzyme that catalyzes the hydrolysis of phosphodiester bonds in chains of RNA.
8429	phosphatidylethanolamine binding	F	Interacting selectively and non-covalently with phosphatidylethanolamine, any of a class of glycerophospholipids in which a phosphatidyl group is esterified to the hydroxyl group of ethanolamine.
8430	selenium binding	F	Interacting selectively and non-covalently with selenium (Se).
8431	vitamin E binding	F	Interacting selectively and non-covalently with vitamin E, tocopherol, which includes a series of eight structurally similar compounds. Alpha-tocopherol is the most active form in humans and is a powerful biological antioxidant.
8432	JUN kinase binding	F	Interacting selectively and non-covalently with JUN kinase, an enzyme that catalyzes the phosphorylation and activation of members of the JUN family.
8434	calcitriol receptor activity	F	Combining with calcitriol, the hormonally active form of vitamin D3, and transmitting the signal to the transcriptional machinery by interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription by RNA polymerase II.
8437	thyrotropin-releasing hormone activity	F	The action characteristic of thyrotropin-releasing hormone (TRH), a hormone released by the mammalian hypothalamus into the hypophyseal-portal circulation in response to neural and/or chemical stimuli. Upon receptor binding, TRH increases the secretion of thyroid-stimulating hormone by the anterior pituitary.
8440	inositol-1,4,5-trisphosphate 3-kinase activity	F	Catalysis of the reaction: 1D-myo-inositol 1,4,5-trisphosphate + ATP = 1D-myo-inositol 1,3,4,5-tetrakisphosphate + ADP + 2 H(+).
8441	3'(2'),5'-bisphosphate nucleotidase activity	F	Catalysis of the reaction: adenosine 3',5'-bisphosphate + H2O = adenosine 5'-phosphate + phosphate.
8442	3-hydroxyisobutyrate dehydrogenase activity	F	Catalysis of the reaction: 3-hydroxy-2-methylpropanoate + NAD+ = 2-methyl-3-oxopropanoate + NADH + H+.
8443	phosphofructokinase activity	F	Catalysis of the transfer of a phosphate group, usually from ATP, to a fructose substrate molecule.
8444	CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity	F	Catalysis of the reaction: sn-glycerol 3-phosphate + CDP-diacylglycerol = 3-(3-sn-phosphatidyl)-sn-glycerol 1-phosphate + CMP + H(+).
8445	D-aspartate oxidase activity	F	Catalysis of the reaction: D-aspartate + H2O + O2 = oxaloacetate + NH3 + hydrogen peroxide.
8446	GDP-mannose 4,6-dehydratase activity	F	Catalysis of the reaction: GDP-alpha-D-mannose = GDP-4-dehydro-6-deoxy-alpha-D-mannose + H(2)O.
8447	L-ascorbate oxidase activity	F	Catalysis of the reaction: 2 L-ascorbate + O2 = 2 dehydroascorbate + 2 H2O.
8448	N-acetylglucosamine-6-phosphate deacetylase activity	F	Catalysis of the reaction: N-acetyl-D-glucosamine 6-phosphate + H2O = D-glucosamine 6-phosphate + acetate.
8449	N-acetylglucosamine-6-sulfatase activity	F	Catalysis of the hydrolysis of the 6-sulfate group of the N-acetyl-D-glucosamine 6-sulfate units of heparan sulfate and keratan sulfate.
8452	RNA ligase activity	F	Catalysis of the formation of a phosphodiester bond between a hydroxyl group at the end of one RNA chain and the 5'-phosphate group at the end of another.
8453	alanine-glyoxylate transaminase activity	F	Catalysis of the reaction: L-alanine + glyoxylate = pyruvate + glycine.
8454	alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity	F	Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + (N-acetyl-beta-D-glucosaminyl-1,2)-alpha-D-mannosyl-1,3-(beta-N-acetyl-D-glucosaminyl-1,2-alpha-D-mannosyl-1,6)-beta-D-mannosyl-R = UDP + N-acetyl-beta-D-glucosaminyl-1,4-(N-acetyl-D-glucosaminyl-1,2)-alpha-D-mannosyl-1,3-(beta-N-acetyl-D-glucosaminyl-1,2-alpha-D-mannosyl-1,6)-beta-D-mannosyl-R.
8455	alpha-1,6-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity	F	Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + alpha-D-mannosyl-1,6-(N-acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl-1,3)-beta-D-mannosyl-R = UDP + N-acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl-1,6-(N-acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl-1,3)-beta-D-mannosyl-R.
8456	alpha-N-acetylgalactosaminidase activity	F	Catalysis of the hydrolysis of terminal non-reducing N-acetyl-D-galactosamine residues in N-acetyl-alpha-D-galactosaminides.
8457	beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity	F	Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-beta-D-glucosylceramide = UDP + N-acetyl-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-beta-D-glucosylceramide.
8458	carnitine O-octanoyltransferase activity	F	Catalysis of the reaction: (R)-carnitine + octanoyl-CoA = (S)-octanoylcarnitine + CoA.
8459	chondroitin 6-sulfotransferase activity	F	Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + chondroitin = adenosine 3',5'-bisphosphate + chondroitin 6'-sulfate.
8460	dTDP-glucose 4,6-dehydratase activity	F	Catalysis of the reaction: dTDP-glucose = dTDP-4-dehydro-6-deoxy-alpha-D-glucose + H(2)O.
8463	formylmethionine deformylase activity	F	Catalysis of the reaction: N-formyl-L-methionine + H(2)O = L-methionine + formate.
8465	glycerate dehydrogenase activity	F	Catalysis of the reaction: (R)-glycerate + NAD+ = hydroxypyruvate + NADH + H+.
8466	glycogenin glucosyltransferase activity	F	Catalysis of the reaction: UDP-glucose + glycogenin = UDP + glucosylglycogenin.
8467	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity	F	Catalysis of the reaction: 3'-phosphoadenylyl sulfate + [heparan sulfate]-glucosamine = adenosine 3',5'-bisphosphate + [heparan sulfate]-glucosamine 3-sulfate. The [heparan sulfate]-glucosamine 3-sulfate has a substrate consensus sequence of Glc(N2S>NAc)+/-6S GlcA GlcN2S*+/-6S GlcA>IdoA+/-2S Glc(N2S/NAc)+/-6S.
8469	histone-arginine N-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + (histone)-arginine = S-adenosyl-L-homocysteine + (histone)-N-methyl-arginine.
8470	isovaleryl-CoA dehydrogenase activity	F	Catalysis of the reaction: 3-methylbutanoyl-CoA + ETF = 3-methylbut-2-enoyl-CoA + reduced ETF.
8473	ornithine cyclodeaminase activity	F	Catalysis of the reaction: L-ornithine = L-proline + NH(4)(+).
8474	palmitoyl-(protein) hydrolase activity	F	Catalysis of the reaction: palmitoyl-protein + H2O = palmitate + protein.
8475	procollagen-lysine 5-dioxygenase activity	F	Catalysis of the reaction: procollagen L-lysine + 2-oxoglutarate + O2 = procollagen 5-hydroxy-L-lysine + succinate + CO2.
8476	protein-tyrosine sulfotransferase activity	F	Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + protein tyrosine = adenosine 3',5'-bisphosphate + protein tyrosine-O-sulfate.
8477	purine nucleosidase activity	F	Catalysis of the reaction: a N-D-ribosylpurine + H2O = a purine + D-ribose.
8478	pyridoxal kinase activity	F	Catalysis of the reaction: ATP + pyridoxal = ADP + pyridoxal 5'-phosphate.
8479	queuine tRNA-ribosyltransferase activity	F	Catalysis of the reaction: tRNA guanine + queuine = tRNA queuine + guanine.
8480	sarcosine dehydrogenase activity	F	Catalysis of the reaction: sarcosine + H2O + electron-transfer flavoprotein = glycine + formaldehyde + reduced electron-transfer flavoprotein.
8481	sphinganine kinase activity	F	Catalysis of the reaction: ATP + sphinganine = ADP + sphinganine 1-phosphate.
8482	sulfite oxidase activity	F	Catalysis of the reaction: H(2)O + O(2) + sulfite = H(2)O(2) + H(+) + sulfate.
8483	transaminase activity	F	Catalysis of the transfer of an amino group to an acceptor, usually a 2-oxo acid.
8484	sulfuric ester hydrolase activity	F	Catalysis of the reaction: RSO-R' + H2O = RSOOH + R'H. This reaction is the hydrolysis of any sulfuric ester bond, any ester formed from sulfuric acid, O=SO(OH)2.
8486	diphosphoinositol-polyphosphate diphosphatase activity	F	Catalysis of the reaction: diphospho-myo-inositol polyphosphate + H2O = myo-inositol polyphosphate + phosphate.
8488	gamma-glutamyl carboxylase activity	F	Catalysis of the reaction: peptidyl-glutamate + reduced vitamin K + CO2 + O2 = peptidyl-gamma-carboxyglutamate + vitamin K epoxide.
8489	UDP-galactose:glucosylceramide beta-1,4-galactosyltransferase activity	F	Catalysis of the reaction: UDP-D-galactose + a glucosylceramide = a lactosylceramide + uridine-5'-diphosphate. The glucosylceramide has sphinganine as the long chain base.
8490	arsenite secondary active transmembrane transporter activity	F	Catalysis of the transfer of arsenite from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Chemiosmotic sources of energy include uniport, symport or antiport.
8493	tetracycline transporter activity	F	Enables the directed movement of tetracycline into, out of or within a cell, or between cells. Tetracycline is a broad spectrum antibiotic that blocks binding of aminoacyl tRNA to the ribosomes of both Gram-positive and Gram-negative organisms (and those of organelles).
8494	translation activator activity	F	Any of a group of soluble proteins functioning in the activation of ribosome-mediated translation of mRNA into a polypeptide.
8495	protoheme IX farnesyltransferase activity	F	Catalysis of the reaction: protoheme IX + (2E,6E)-farnesyl diphosphate + H2O = heme o + diphosphate.
8496	mannan endo-1,6-alpha-mannosidase activity	F	Catalysis of the random hydrolysis of (1->6)-alpha-D-mannosidic linkages in unbranched (1->6)-mannans.
8499	UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity	F	Catalysis of the reaction: UDP-galactose + N-acetylglucosamine = galactose-beta-1,3-N-acetylglucosamine + UDP.
8502	melatonin receptor activity	F	Combining with melatonin, N-acetyl-5-methoxytryptamine, to initiate a change in cell activity. Melatonin is a neuroendocrine substance that stimulates the aggregation of melanosomes in melanophores, thus lightening the skin.
8503	benzodiazepine receptor activity	F	Combining with benzodiazepines, a class of drugs with hypnotic, anxiolytic, anticonvulsive, amnestic and myorelaxant properties, to initiate a change in cell activity.
8504	monoamine transmembrane transporter activity	F	Enables the transfer of monoamines, organic compounds that contain one amino group that is connected to an aromatic ring by an ethylene group (-CH2-CH2-), from one side of the membrane to the other.
8506	sucrose:proton symporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sucrose(out) + H+(out) = sucrose(in) + H+(in).
8507	sodium:iodide symporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: iodide(out) + Na+(out) = iodide(in) + Na+(in).
8508	bile acid:sodium symporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: bile acid(out) + Na+(out) = bile acid(in) + Na+(in).
8509	anion transmembrane transporter activity	F	Enables the transfer of a negatively charged ion from one side of a membrane to the other.
8510	sodium:bicarbonate symporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Na+(out) + HCO3-(out) = Na+(in) + HCO3-(in).
8511	sodium:potassium:chloride symporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Na+(out) + K+(out) + Cl-(out) = Na+(in) + K+(in) + Cl-(in).
8512	sulfate:proton symporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sulfate(out) + H+(out) = sulfate(in) + H+(in).
8513	secondary active organic cation transmembrane transporter activity	F	Catalysis of the transfer of organic cations from one side of the membrane to the other, up the solute's concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction.
8514	organic anion transmembrane transporter activity	F	Enables the transfer of organic anions from one side of a membrane to the other. Organic anions are atoms or small molecules with a negative charge which contain carbon in covalent linkage.
8515	sucrose transmembrane transporter activity	F	Enables the transfer of sucrose from one side of the membrane to the other. Sucrose is the disaccharide O-beta-D-fructofuranosyl-(2->1)-alpha-D-glucopyranoside, a sweet-tasting, non-reducing sugar isolated industrially from sugar beet or sugar cane.
8516	hexose uniporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: hexose(out) = hexose(in).
8517	folic acid transporter activity	F	Enables the directed movement of folic acid (pteroylglutamic acid) into, out of or within a cell, or between cells. Folic acid is widely distributed as a member of the vitamin B complex and is essential for the synthesis of purine and pyrimidines.
8518	reduced folate carrier activity	F	Catalysis of the transfer of reduced folate from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Chemiosmotic sources of energy include uniport, symport or antiport.
8519	ammonium transmembrane transporter activity	F	Enables the transfer of ammonium from one side of a membrane to the other. Ammonium is the cation NH4+ which is formed from N2 by root-nodule bacteria in leguminous plants and is an excretory product in ammonotelic animals.
8520	L-ascorbate:sodium symporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ascorbate(out) + Na+(out) = ascorbate(in) + Na+(in).
8521	acetyl-CoA transporter activity	F	Enables the directed movement of acetyl-CoA into, out of or within a cell, or between cells. Acetyl-CoA is a derivative of coenzyme A in which the sulfhydryl group is acetylated; it is a metabolite derived from several pathways (e.g. glycolysis, fatty acid oxidation, amino-acid catabolism) and is further metabolized by the tricarboxylic acid cycle. It is a key intermediate in lipid and terpenoid biosynthesis.
8523	sodium-dependent multivitamin transmembrane transporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: multivitamin(out) + Na+(out) = multivitamin(in) + Na+(in). Multivitamins include pantothenate, biotin and lipoate.
8524	glucose 6-phosphate:phosphate antiporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucose 6-phosphate(out) + phosphate(in) = glucose 6-phosphate(in) + phosphate(out).
8525	phosphatidylcholine transporter activity	F	Enables the directed movement of phosphatidylcholine into, out of or within a cell, or between cells. Phosphatidylcholine refers to a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of choline.
8526	phosphatidylinositol transporter activity	F	Enables the directed movement of phosphatidylinositol into, out of or within a cell, or between cells. Phosphatidylinositol refers to any glycophospholipids with its sn-glycerol 3-phosphate residue is esterified to the 1-hydroxyl group of 1D-myo-inositol.
8527	taste receptor activity	F	Combining with soluble compounds to initiate a change in cell activity. These receptors are responsible for the sense of taste.
8528	G-protein coupled peptide receptor activity	F	Combining with a peptide and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.
8531	riboflavin kinase activity	F	Catalysis of the reaction: ATP + riboflavin = ADP + FMN + 2 H(+).
8532	N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity	F	Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + beta-D-galactosyl-1,4-N-acetyl-D-glucosaminyl-R = UDP + N-acetyl-beta-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-N-acetyl-D-glucosaminyl-R.
8534	oxidized purine nucleobase lesion DNA N-glycosylase activity	F	Catalysis of the removal of oxidized purine bases by cleaving the N-C1' glycosidic bond between the oxidized purine and the deoxyribose sugar. The reaction involves the formation of a covalent enzyme-substrate intermediate. Release of the enzyme and free base by a beta-elimination or a beta, gamma-elimination mechanism results in the cleavage of the DNA backbone 3' of the apurinic (AP) site.
8535	respiratory chain complex IV assembly	P	The aggregation, arrangement and bonding together of a set of components to form respiratory chain complex IV (also known as cytochrome c oxidase), the terminal member of the respiratory chain of the mitochondrion and some aerobic bacteria. Cytochrome c oxidases are multi-subunit enzymes containing from 13 subunits in the mammalian mitochondrial form to 3-4 subunits in the bacterial forms.
8536	Ran GTPase binding	F	Interacting selectively and non-covalently with Ran, a conserved Ras-like GTP-binding protein, implicated in nucleocytoplasmic transport, cell cycle progression, spindle assembly, nuclear organization and nuclear envelope (NE) assembly.
8537	proteasome activator complex	C	A multisubunit complex that activates the hydrolysis of small nonubiquitinated peptides by binding to the proteasome core complex.
8540	proteasome regulatory particle, base subcomplex	C	The subcomplex of the proteasome regulatory particle that directly associates with the proteasome core complex.
8541	proteasome regulatory particle, lid subcomplex	C	The subcomplex of the proteasome regulatory particle that forms the peripheral lid, which is added on top of the base subcomplex.
8542	visual learning	P	Any process in an organism in which a change in behavior of an individual occurs in response to repeated exposure to a visual cue.
8543	fibroblast growth factor receptor signaling pathway	P	The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands.
8544	epidermis development	P	The process whose specific outcome is the progression of the epidermis over time, from its formation to the mature structure. The epidermis is the outer epithelial layer of an animal, it may be a single layer that produces an extracellular material (e.g. the cuticle of arthropods) or a complex stratified squamous epithelium, as in the case of many vertebrate species.
8545	JUN kinase kinase activity	F	Catalysis of the phosphorylation of tyrosine and threonine residues in a c-Jun NH2-terminal kinase (JNK), a member of a subgroup of mitogen-activated protein kinases (MAPKs), which signal in response to cytokines and exposure to environmental stress. JUN kinase kinase (JNKK) is a dual-specificity protein kinase kinase and requires activation by a serine/threonine kinase JUN kinase kinase kinase.
8551	cadmium-exporting ATPase activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Cd2+(in) -> ADP + phosphate + Cd2+(out).
8553	hydrogen-exporting ATPase activity, phosphorylative mechanism	F	Catalysis of the transfer of protons from one side of a membrane to the other according to the reaction: ATP + H2O + H+(in) -> ADP + phosphate + H+(out). These transporters use a phosphorylative mechanism, which have a phosphorylated intermediate state during the ion transport cycle.
8554	sodium-exporting ATPase activity, phosphorylative mechanism	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Na+(in) -> ADP + phosphate + Na+(out); by a phosphorylative mechanism.
8555	chloride-transporting ATPase activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Cl-(out) = ADP + phosphate + Cl-(in).
8556	potassium-transporting ATPase activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + K+(out) = ADP + phosphate + K+(in).
8558	guanine-transporting ATPase activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + guanine(out) = ADP + phosphate + guanine(in).
8559	xenobiotic-transporting ATPase activity	F	Catalysis of the reaction: ATP + H2O + xenobiotic(in) = ADP + phosphate + xenobiotic(out).
8564	protein-exporting ATPase activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + protein+(in) -> ADP + phosphate + protein+(out); drives the concomitant secretion of proteins.
8565	protein transporter activity	F	Enables the directed movement of proteins into, out of or within a cell, or between cells.
8566	mitochondrial protein-transporting ATPase activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O = ADP + phosphate; drives the transport of proteins into the mitochondrion via the mitochondrial inner membrane translocase complex.
8568	microtubule-severing ATPase activity	F	Catalysis of the reaction: ATP + H2O = ADP + phosphate. Catalysis of the severing of a microtubule at a specific spot along its length, coupled to the hydrolysis of ATP.
8569	ATP-dependent microtubule motor activity, minus-end-directed	F	Catalysis of movement along a microtubule toward the minus end, coupled to the hydrolysis of ATP.
8574	ATP-dependent microtubule motor activity, plus-end-directed	F	Catalysis of movement along a microtubule toward the plus end, coupled to the hydrolysis of ATP.
8579	JUN kinase phosphatase activity	F	Catalysis of the reaction: JUN kinase serine/threonine/tyrosine phosphate + H2O = JUN kinase serine/threonine/tyrosine + phosphate.
8582	regulation of synaptic growth at neuromuscular junction	P	Any process that modulates the frequency, rate or extent of synaptic growth at neuromuscular junctions.
8583	mystery cell differentiation	P	The process in which an undifferentiated cell acquires the features of a mystery cell. The mystery cells are a precluster of cells that emerge from the compound eye morphogenetic furrow, normally positioned between R3 and R4. They then disappear into the surrounding pool of undifferentiated cells and have no known fate in the mature ommatidium. An example of this process is found in Drosophila melanogaster.
8584	male gonad development	P	The process whose specific outcome is the progression of the male gonad over time, from its formation to the mature structure.
8585	female gonad development	P	The process whose specific outcome is the progression of the female gonad over time, from its formation to the mature structure.
8586	imaginal disc-derived wing vein morphogenesis	P	The process in which anatomical structures of the veins on an imaginal disc-derived wing are generated and organized.
8587	imaginal disc-derived wing margin morphogenesis	P	The process in which the anatomical structures of the imaginal disc-derived wing margin are generated and organized. The wing margin is a strip of cells in the third instar disc at the boundary between the presumptive dorsal and ventral surfaces of the wing blade.
8588	release of cytoplasmic sequestered NF-kappaB	P	The release of NF-kappaB from specific molecules in the cytoplasm to which it was bound, thereby allowing its translocation into the nucleus.
8589	regulation of smoothened signaling pathway	P	Any process that modulates the frequency, rate or extent of smoothened signaling.
8591	regulation of Wnt signaling pathway, calcium modulating pathway	P	Any process that modulates the frequency, rate or extent of the series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors leads to an increase in intracellular calcium and activation of protein kinase C (PKC).
8592	regulation of Toll signaling pathway	P	Any process that modulates the frequency, rate or extent of the Tl signaling pathway.
8593	regulation of Notch signaling pathway	P	Any process that modulates the frequency, rate or extent of the Notch signaling pathway.
8594	photoreceptor cell morphogenesis	P	The process in which the structures of a photoreceptor cell are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a photoreceptor cell, a sensory cell that reacts to the presence of light. An example of this is found in Drosophila melanogaster.
8595	anterior/posterior axis specification, embryo	P	The specification of the anterior/posterior axis of the embryo by the products of genes expressed maternally and genes expressed in the zygote.
8597	calcium-dependent protein serine/threonine phosphatase regulator activity	F	Modulation of the activity of the enzyme calcium-dependent protein serine/threonine phosphatase.
8603	cAMP-dependent protein kinase regulator activity	F	Modulation of the activity of the enzyme cAMP-dependent protein kinase.
8607	phosphorylase kinase regulator activity	F	Modulation of the activity of the enzyme phosphorylase kinase.
8608	attachment of spindle microtubules to kinetochore	P	The process in which spindle microtubules become physically associated with the proteins making up the kinetochore complex.
8609	alkylglycerone-phosphate synthase activity	F	Catalysis of the reaction: 1-acyl-glycerone 3-phosphate + a long-chain alcohol = 1-alkyl-glycerone 3-phosphate + a long-chain acid anion.
8610	lipid biosynthetic process	P	The chemical reactions and pathways resulting in the formation of lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent.
8611	ether lipid biosynthetic process	P	The chemical reactions and pathways resulting in the formation of ether lipids, lipids that contain (normally) one lipid alcohol in ether linkage to one of the carbon atoms (normally C-1) of glycerol.
8612	peptidyl-lysine modification to peptidyl-hypusine	P	The modification of peptidyl-lysine to form hypusine, peptidyl-N6-(4-amino-2-hydroxybutyl)-L-lysine.
8613	diuretic hormone activity	F	The action characteristic of a diuretic hormone, any peptide hormone that, upon receptor binding, regulates water balance and fluid secretion.
8614	pyridoxine metabolic process	P	The chemical reactions and pathways involving pyridoxine, 2-methyl-3-hydroxy-4,5-bis(hydroxymethyl)pyridine, one of the vitamin B6 compounds. Pyridoxal, pyridoxamine and pyridoxine are collectively known as vitamin B6, and are efficiently converted to the biologically active form of vitamin B6, pyridoxal phosphate.
8615	pyridoxine biosynthetic process	P	The chemical reactions and pathways resulting in the formation of pyridoxine, 2-methyl-3-hydroxy-4,5-bis(hydroxymethyl)pyridine, one of the vitamin B6 compounds.
8616	queuosine biosynthetic process	P	The chemical reactions and pathways resulting in the formation of queuosines, any of a series of nucleosides found in tRNA and having an additional pentenyl ring added via an NH group to the methyl group of 7-methylguanosine. The pentenyl ring may carry other substituents.
8617	guanosine metabolic process	P	The chemical reactions and pathways involving guanine, guanine riboside, a nucleoside with a wide species distribution.
8618	7-methylguanosine metabolic process	P	The chemical reactions and pathways involving 7-methylguanosine, a modified nucleoside that forms a cap at the 5'-terminus of eukaryotic mRNA.
8622	epsilon DNA polymerase complex	C	A heterotetrameric DNA polymerase complex that catalyzes processive DNA synthesis in the absence of PCNA, but is further stimulated in the presence of PCNA. The complex contains a large catalytic subunit and three small subunits, and is best characterized in Saccharomyces, in which the subunits are named Pol2p, Dpb2p, Dpb3p, and Dpb4p. Some evidence suggests that DNA polymerase epsilon is the leading strand polymerase; it is also involved in nucleotide-excision repair and mismatch repair.
8623	CHRAC	C	An ISWI complex that contains an ATPase subunit of the ISWI family (SNF2H in mammals, Isw2 in S. cerevisiae), an ACF1 homolog, and additional small histone fold subunits (generally two of these, but Xenopus has only one and some additional non-conserved subunits). CHRAC plays roles in the regulation of RNA polymerase II transcription and in DNA replication and repair.
8625	extrinsic apoptotic signaling pathway via death domain receptors	P	A series of molecular signals in which a signal is conveyed from the cell surface to trigger the apoptotic death of a cell. The pathway starts with a ligand binding to a death domain receptor on the cell surface, and ends when the execution phase of apoptosis is triggered.
8626	granzyme-mediated apoptotic signaling pathway	P	A series of molecular signals induced by granzymes which triggers the apoptotic death of a cell. The pathway starts with reception of a granzyme signal, and ends when the execution phase of apoptosis is triggered. Granzymes are serine proteases that are secreted by cytotoxic T cells and natural killer cells to induce apoptosis in target cells.
8627	intrinsic apoptotic signaling pathway in response to osmotic stress	P	A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced in response to changes in intracellular ion homeostasis, and ends when the execution phase of apoptosis is triggered.
8628	hormone-mediated apoptotic signaling pathway	P	A series of molecular signals mediated by the detection of a hormone, and which triggers the apoptotic signaling pathway in a cell. The pathway starts with reception of a hormone signal, and ends when the execution phase of apoptosis is triggered.
8630	intrinsic apoptotic signaling pathway in response to DNA damage	P	A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced by the detection of DNA damage, and ends when the execution phase of apoptosis is triggered.
8631	intrinsic apoptotic signaling pathway in response to oxidative stress	P	A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced in response to oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, and ends when the execution phase of apoptosis is triggered.
8635	activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c	P	Any process that initiates the activity of the inactive enzyme cysteine-type endopeptidase in the context of an apoptotic process and is mediated by cytochrome c.
8637	apoptotic mitochondrial changes	P	The morphological and physiological alterations undergone by mitochondria during apoptosis.
8641	small protein activating enzyme activity	F	Catalysis of the activation of small proteins, such as ubiquitin or ubiquitin-like proteins, through the formation of an ATP-dependent high-energy thiolester bond.
8643	carbohydrate transport	P	The directed movement of carbohydrate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Carbohydrates are any of a group of organic compounds based of the general formula Cx(H2O)y.
8645	hexose transport	P	The directed movement of hexose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Hexoses are any aldoses with a chain of six carbon atoms in the molecule.
8646	high-affinity hexose transport	P	The directed, high-affinity movement of a hexose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.
8647	low-affinity hexose transport	P	The directed, low-affinity movement of a hexose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. In low-affinity transport the transporter is able to bind the solute only if it is only present at very low concentrations.
8649	rRNA methyltransferase activity	F	Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a nucleoside residue in an rRNA molecule.
8650	rRNA (uridine-2'-O-)-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing 2'-O-methyluridine.
8652	cellular amino acid biosynthetic process	P	The chemical reactions and pathways resulting in the formation of amino acids, organic acids containing one or more amino substituents.
8653	lipopolysaccharide metabolic process	P	The chemical reactions and pathways involving lipopolysaccharides, any of a group of related, structurally complex components of the outer membrane of Gram-negative bacteria. Lipopolysaccharides consist three covalently linked regions, lipid A, core oligosaccharide, and an O side chain. Lipid A is responsible for the toxicity of the lipopolysaccharide.
8654	phospholipid biosynthetic process	P	The chemical reactions and pathways resulting in the formation of phospholipids, any lipid containing phosphoric acid as a mono- or diester.
8655	pyrimidine-containing compound salvage	P	Any process that generates a pyrimidine-containing compound, any nucleobase, nucleoside, nucleotide or nucleic acid that contains a pyrimidine base, from derivatives of them without de novo synthesis.
8656	cysteine-type endopeptidase activator activity involved in apoptotic process	F	Increases the rate of proteolysis catalyzed by a cysteine-type endopeptidase involved in the apoptotic process.
8657	DNA topoisomerase (ATP-hydrolyzing) inhibitor activity	F	Stops, prevents or reduces the activity of ATP-hydrolyzing DNA topoisomerase. ATP-hydrolyzing DNA topoisomerase catalyzes the DNA topological transformation by transiently cleaving a pair of complementary DNA strands to form a gate through which a second double-stranded DNA segment is passed, after which the severed strands in the first DNA segment are rejoined; product release is coupled to ATP binding and hydrolysis; changes the linking number in multiples of 2.
8658	penicillin binding	F	Interacting selectively and non-covalently with penicillin, any antibiotic that contains the condensed beta-lactamthiazolidine ring system.
8659	(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity	F	Catalysis of the reaction: (3R)-3-hydroxytetradecanoyl-[acyl-carrier protein] = tetradecenoyl-[acyl-carrier protein] + H2O.
8660	1-aminocyclopropane-1-carboxylate deaminase activity	F	Catalysis of the reaction: 1-aminocyclopropane-1-carboxylate + H(2)O = 2-oxobutanate + NH(4)(+).
8661	1-deoxy-D-xylulose-5-phosphate synthase activity	F	Catalysis of the reaction: D-glyceraldehyde 3-phosphate + H(+) + pyruvate = 1-deoxy-D-xylulose 5-phosphate + CO(2).
8662	1-phosphofructokinase activity	F	Catalysis of the reaction: ATP + D-fructose 1-phosphate = ADP + D-fructose 1,6-bisphosphate.
8663	2',3'-cyclic-nucleotide 2'-phosphodiesterase activity	F	Catalysis of the reaction: nucleoside 2',3'-cyclic phosphate + H2O = nucleoside 3'-phosphate.
8664	2'-5'-RNA ligase activity	F	Catalysis of the formation of a phosphodiester bond between the 2'-hydroxyl group at the end of one DNA chain and the 5'-phosphate group at the end of another.
8665	2'-phosphotransferase activity	F	Catalysis of the transfer of a phosphate group from one compound to the 2' position of another.
8666	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase activity	F	Catalysis of the reaction: (S)-2,3,4,5-tetrahydrodipicolinate + H(2)O + succinyl-CoA = L-2-succinylamino-6-oxopimelate + CoA.
8667	2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase activity	F	Catalysis of the reaction: (2S,3S)-2,3-dihydroxy-2,3-dihydrobenzoate + NAD(+) = 2,3-dihydroxybenzoate + H(+) + NADH.
8668	(2,3-dihydroxybenzoyl)adenylate synthase activity	F	Catalysis of the reaction: 2,3-dihydroxybenzoate + ATP = 2,3-dihydroxybenzoyl 5'-adenylate + diphosphate.
8670	2,4-dienoyl-CoA reductase (NADPH) activity	F	Catalysis of the reaction: trans-2,3-didehydroacyl-CoA + NADP+ = trans,trans-2,3,4,5-tetradehydroacyl-CoA + NADPH + H+.
8671	2-dehydro-3-deoxygalactonokinase activity	F	Catalysis of the reaction: 2-dehydro-3-deoxy-D-galactonate + ATP = 6-phospho-2-dehydro-3-deoxy-D-galactonate + ADP + 2 H(+).
8672	2-dehydro-3-deoxyglucarate aldolase activity	F	Catalysis of the reaction: 2-dehydro-3-deoxy-D-glucarate = pyruvate + tartronate semialdehyde.
8673	2-dehydro-3-deoxygluconokinase activity	F	Catalysis of the reaction: 2-dehydro-3-deoxy-D-gluconate + ATP = 2-dehydro-3-deoxy-6-phospho-D-gluconate + ADP + 2 H(+).
8674	2-dehydro-3-deoxy-6-phosphogalactonate aldolase activity	F	Catalysis of the reaction: 6-phospho-2-dehydro-3-deoxy-D-galactonate = D-glyceraldehyde 3-phosphate + pyruvate.
8675	2-dehydro-3-deoxy-phosphogluconate aldolase activity	F	Catalysis of the reaction: 2-dehydro-3-deoxy-D-gluconate 6-phosphate = pyruvate + D-glyceraldehyde 3-phosphate.
8676	3-deoxy-8-phosphooctulonate synthase activity	F	Catalysis of the reaction: D-arabinose 5-phosphate + H(2)O + phosphoenolpyruvate = 8-phospho-3-deoxy-D-manno-oct-2-ulosonate + 2 H(+) + phosphate.
8677	2-dehydropantoate 2-reductase activity	F	Catalysis of the reaction: (R)-pantoate + NADP(+) = 2-dehydropantoate + H(+) + NADPH.
8678	2-deoxy-D-gluconate 3-dehydrogenase activity	F	Catalysis of the reaction: 2-deoxy-D-gluconate + NAD+ = 3-dehydro-2-deoxy-D-gluconate + NADH + H+.
8679	2-hydroxy-3-oxopropionate reductase activity	F	Catalysis of the reaction: (R)-glycerate + NADP+ = 2-hydroxy-3-oxopropanoate + NADPH + H+.
8681	2-octaprenyl-6-methoxyphenol hydroxylase activity	F	Catalysis of the reaction: 2-octaprenyl-6-methoxyphenol + O2 + 4 H+ = 2-octaprenyl-6-methoxy-1,4-benzoquinol + H2O.
8682	2-octoprenyl-3-methyl-6-methoxy-1,4-benzoquinone hydroxylase activity	F	Catalysis of the reaction: 2-octoprenyl-3-methyl-6-methoxy-1,4-benzoquinone + O2 = 2-octoprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinone.
8683	2-oxoglutarate decarboxylase activity	F	Catalysis of the reaction: 2-oxoglutarate + H(+) = CO(2) + succinate semialdehyde.
8684	2-oxopent-4-enoate hydratase activity	F	Catalysis of the reaction: 4-hydroxy-2-oxopentanoate = 2-oxopent-4-enoate + H2O.
8685	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity	F	Catalysis of the reaction: 4-CDP-2-C-methyl-D-erythritol 2-phosphate = 2-C-methyl-D-erythritol 2,4-cyclic diphosphate + CMP.
8686	3,4-dihydroxy-2-butanone-4-phosphate synthase activity	F	Catalysis of the reaction: D-ribulose 5-phosphate = (2S)-2-hydroxy-3-oxobutyl phosphate + formate + H(+).
8687	3,4-dihydroxyphenylacetate 2,3-dioxygenase activity	F	Catalysis of the reaction: 3,4-dihydroxyphenylacetate + O(2) = 5-formyl-2-hydroxyhepta-2,4-dienedioate + H(+).
8688	3-(3-hydroxyphenyl)propionate hydroxylase activity	F	Catalysis of the reaction: 3-(3-hydroxyphenyl)propionate + NADH + oxygen + H+ = 3-(2,3-dihydroxyphenyl)propionate + NAD+ + H2O.
8689	3-demethylubiquinone-9 3-O-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + 3-demethylubiquinone-9 = S-adenosyl-L-homocysteine + ubiquinone-9.
8690	3-deoxy-manno-octulosonate cytidylyltransferase activity	F	Catalysis of the reaction: CTP + 3-deoxy-D-manno-octulosonate = diphosphate + CMP-3-deoxy-D-manno-octulosonate.
8691	3-hydroxybutyryl-CoA dehydrogenase activity	F	Catalysis of the reaction: (S)-3-hydroxybutanoyl-CoA + NADP+ = 3-acetoacetyl-CoA + NADPH + H+.
8692	3-hydroxybutyryl-CoA epimerase activity	F	Catalysis of the reaction: (S)-3-hydroxybutanoyl-CoA = (R)-3-hydroxybutanoyl-CoA.
8693	3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase activity	F	Catalysis of the reaction: (3R)-3-hydroxydecanoyl-[acyl-carrier protein] = 2,3-decenoyl-[acyl-carrier protein] or 3,4-decenoyl-[acyl-carrier protein] + H2O.
8694	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity	F	Catalysis of the reaction: 3-octaprenyl-4-hydroxy benzoate = 2-octaprenylphenol + CO2.
8695	3-phenylpropionate dioxygenase activity	F	Catalysis of the reaction: 3-phenylpropionate + NADH + H+ + O2 = NAD+ + cis-3-(3-carboxyethyl)-3,5-cyclohexadiene-1,2-diol.
8696	4-amino-4-deoxychorismate lyase activity	F	Catalysis of the reaction: 4-amino-4-deoxychorismate = 4-aminobenzoate + H(+) + pyruvate.
8697	4-deoxy-L-threo-5-hexosulose-uronate ketol-isomerase activity	F	Catalysis of the reaction: 5-dehydro-4-deoxy-D-glucuronate = 3-deoxy-D-glycero-2,5-hexodiulosonate.
8700	4-hydroxy-2-oxoglutarate aldolase activity	F	Catalysis of the reaction: 4-hydroxy-2-oxoglutarate = pyruvate + glyoxylate.
8701	4-hydroxy-2-oxovalerate aldolase activity	F	Catalysis of the reaction: 4-hydroxy-2-oxopentanoate = acetaldehyde + pyruvate.
8703	5-amino-6-(5-phosphoribosylamino)uracil reductase activity	F	Catalysis of the reaction: 5-amino-6-(5-phosphoribitylamino)uracil + NADP(+) = 5-amino-6-(5-phosphoribosylamino)uracil + H(+) + NADPH.
8704	5-carboxymethyl-2-hydroxymuconate delta-isomerase activity	F	Catalysis of the reaction: 5-carboxymethyl-2-hydroxymuconate = 5-carboxy-2-oxohept-3-enedioate.
8705	methionine synthase activity	F	Catalysis of the reaction: (6S)-5-methyl-5,6,7,8-tetrahydrofolate + L-homocysteine = (6S)-5,6,7,8-tetrahydrofolate + L-methionine.
8706	6-phospho-beta-glucosidase activity	F	Catalysis of the reaction: 6-phospho-beta-D-glucoside-(1,4)-D-glucose + H2O = D-glucose 6-phosphate + glucose.
8707	4-phytase activity	F	Catalysis of the reaction: myo-inositol hexakisphosphate + H2O = 1-myo-inositol 1,2,3,4,5-pentakisphosphate + phosphate.
8709	cholate 7-alpha-dehydrogenase activity	F	Catalysis of the reaction: cholate + NAD(+) = 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanate + H(+) + NADH.
8710	8-amino-7-oxononanoate synthase activity	F	Catalysis of the reaction: L-alanine + H(+) + pimelyl-CoA = 8-amino-7-oxononanoate + CO(2) + CoA.
8712	ADP-glyceromanno-heptose 6-epimerase activity	F	Catalysis of the reaction: ADP-D-glycero-D-manno-heptose = ADP-L-glycero-D-manno-heptose.
8713	ADP-heptose-lipopolysaccharide heptosyltransferase activity	F	Catalysis of the reaction: heptosyl-KDO2-lipid A + ADP-L-glycero-beta-D-manno-heptose = heptosyl2-KDO2-lipid A + ADP + H+.
8714	AMP nucleosidase activity	F	Catalysis of the reaction: AMP + H(2)O = D-ribose 5-phosphate + adenine.
8715	CDP-diacylglycerol diphosphatase activity	F	Catalysis of the reaction: CDP-diacylglycerol + H(2)O = a phosphatidate + CMP + 2 H(+).
8716	D-alanine-D-alanine ligase activity	F	Catalysis of the reaction: 2 D-alanine + ATP = D-alanyl-D-alanine + ADP + 2 H(+) + phosphate.
8718	D-amino-acid dehydrogenase activity	F	Catalysis of the reaction: a D-amino acid + H2O + acceptor = a 2-oxo acid + NH3 + reduced acceptor.
8719	dihydroneopterin triphosphate 2'-epimerase activity	F	Catalysis of the reaction: dihydroneopterin triphosphate = dihydromonapterin-triphosphate.
8720	D-lactate dehydrogenase activity	F	Catalysis of the reaction: (R)-lactate + NAD(+) = H(+) + NADH + pyruvate.
8721	D-serine ammonia-lyase activity	F	Catalysis of the reaction: D-serine = pyruvate + NH3.
8725	DNA-3-methyladenine glycosylase activity	F	Catalysis of the reaction: DNA containing 3-methyladenine + H2O = DNA with abasic site + 3-methyladenine. This reaction is the hydrolysis of DNA by cleavage of the N-C1' glycosidic bond between the damaged DNA 3-methyladenine and the deoxyribose sugar to remove the 3-methyladenine, leaving an abasic site.
8726	alkanesulfonate monooxygenase activity	F	Catalysis of the reaction: an alkanesulfonate + O2 + FMNH2 = an aldehyde + sulfite + H2O + FMN.
8727	GDP-mannose mannosyl hydrolase activity	F	Catalysis of the reaction: GDP-alpha-D-mannose + H2O = GDP + D-mannose + H+.
8728	GTP diphosphokinase activity	F	Catalysis of the reaction: ATP + GTP = AMP + guanosine 3'-diphosphate 5'-triphosphate.
8730	L(+)-tartrate dehydratase activity	F	Catalysis of the reaction: L-tartrate = H(2)O + oxaloacetate.
8732	L-allo-threonine aldolase activity	F	Catalysis of the reaction: L-allo-threonine = glycine + acetaldehyde.
8733	L-arabinose isomerase activity	F	Catalysis of the reaction: L-arabinose = L-ribulose.
8734	L-aspartate oxidase activity	F	Catalysis of the reaction: L-aspartate + O2 = iminosuccinate + hydrogen peroxide.
8735	carnitine dehydratase activity	F	Catalysis of the reaction: (R)-carnitine = crotono-betaine + H(2)O.
8736	L-fucose isomerase activity	F	Catalysis of the reaction: L-fucose = L-fuculose.
8737	L-fuculokinase activity	F	Catalysis of the reaction: L-fuculose + ATP = L-fuculose 1-phosphate + ADP + 2 H(+).
8738	L-fuculose-phosphate aldolase activity	F	Catalysis of the reaction: L-fuculose 1-phosphate = (S)-lactaldehyde + glycerone phosphate.
8740	L-rhamnose isomerase activity	F	Catalysis of the reaction: L-rhamnose = L-rhamnulose.
8741	ribulokinase activity	F	Catalysis of the reaction: ATP + L(or D)-ribulose = ADP + L(or D)-ribulose 5-phosphate.
8742	L-ribulose-phosphate 4-epimerase activity	F	Catalysis of the reaction: L-ribulose 5-phosphate = D-xylulose 5-phosphate.
8743	L-threonine 3-dehydrogenase activity	F	Catalysis of the reaction: L-threonine + NAD(+) = aminoacetone + CO(2) + NADH.
8744	L-xylulokinase activity	F	Catalysis of the reaction: ATP + L-xylulose = ADP + L-xylulose 5-phosphate.
8745	N-acetylmuramoyl-L-alanine amidase activity	F	Catalysis of the hydrolysis of the link between N-acetylmuramoyl residues and L-amino acid residues in certain bacterial cell-wall glycopeptides.
8746	NAD(P)+ transhydrogenase activity	F	Catalysis of the reaction: NADPH + H+ + NAD+ = NADP+ + NADH + H+.
8747	N-acetylneuraminate lyase activity	F	Catalysis of the reaction: N-acetylneuraminate = N-acetyl-D-mannosamine + pyruvate.
8748	N-ethylmaleimide reductase activity	F	Catalysis of the reaction: N-ethylmaleimide + NADPH + 2 H+ = N-ethylsuccinimide + NADP+.
8750	NAD(P)+ transhydrogenase (AB-specific) activity	F	Catalysis of the reaction: NADPH + H+ + NAD+ = NADP+ + NADH + H+. The reaction is A-specific (i.e. the pro-R hydrogen is transferred from the 4-position of reduced nicotinamide cofactor) with respect to NAD+ and B-specific (i.e. the pro-S hydrogen is transferred) with respect to NADP+.
8752	FMN reductase activity	F	Catalysis of the reaction: FMNH2 + NAD(P)+ = FMN + NAD(P)H + H+.
8753	NADPH dehydrogenase (quinone) activity	F	Catalysis of the reaction: NADPH + H+ + a quinone = NADP+ + a quinol.
8754	O antigen ligase activity	F	Catalysis of the reaction: Lipid A-core + colanic acid = MLPS.
8755	O antigen polymerase activity	F	Catalysis of the polymerization of o-antigen chains. O-antigens are tetra- and pentasaccharide repeat units of the cell walls of Gram-negative bacteria and are a component of lipopolysaccharide.
8756	o-succinylbenzoate-CoA ligase activity	F	Catalysis of the reaction: 2-succinylbenzoate + ATP + CoA = 2-succinylbenzoyl-CoA + AMP + diphosphate.
8757	S-adenosylmethionine-dependent methyltransferase activity	F	Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a substrate.
8758	UDP-2,3-diacylglucosamine hydrolase activity	F	Catalysis of the reaction: H2O + UDP-2,3-bis(3-hydroxymyristoyl)glucosamine = 2,3-bis(3-hydroxymyristoyl)-beta-D-glucosaminyl 1-phosphate + UMP.
8759	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity	F	Catalysis of the removal of an acetyl group from the 2-N position of glucosamine in the lipid A precursor UDP-3-O-(R-3-hydroxymyristoyl)-N-acetylglucosamine.
8760	UDP-N-acetylglucosamine 1-carboxyvinyltransferase activity	F	Catalysis of the reaction: phosphoenolpyruvate + UDP-N-acetyl-alpha-D-glucosamine = phosphate + UDP-N-acetyl-3-O-(1-carboxyvinyl)-D-glucosamine.
8761	UDP-N-acetylglucosamine 2-epimerase activity	F	Catalysis of the reaction: UDP-N-acetyl-D-glucosamine = UDP-N-acetyl-D-mannosamine.
8762	UDP-N-acetylmuramate dehydrogenase activity	F	Catalysis of the reaction: UDP-N-acetylmuramate + NADP+ = UDP-N-acetyl-3-O-(1-carboxyvinyl)-D-glucosamine + NADPH + H+.
8763	UDP-N-acetylmuramate-L-alanine ligase activity	F	Catalysis of the reaction: L-alanine + ATP + UDP-N-acetylmuramate = ADP + 2 H(+) + phosphate + UDP-N-acetylmuramoyl-L-alanine.
8764	UDP-N-acetylmuramoylalanine-D-glutamate ligase activity	F	Catalysis of the reaction: D-glutamate + ATP + UDP-N-acetylmuramoyl-L-alanine = ADP + 2 H(+) + phosphate + UDP-N-acetylmuramoyl-L-alanyl-D-glutamate.
8765	UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase activity	F	Catalysis of the reaction: meso-2,6-diaminopimelate + ATP + UDP-N-acetylmuramoyl-L-alanyl-D-glutamate = ADP + 2 H(+) + phosphate + UDP-N-acetylmuramoyl-L-alanyl-D-gamma-glutamyl-meso-2,6-diaminoheptanedioate.
8766	UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity	F	Catalysis of the reaction: ATP + UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminoheptanedioate + D-alanyl-D-alanine = ADP + phosphate + UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-6-carboxy-L-lysyl-D-alanyl-D-alanine.
8767	UDP-galactopyranose mutase activity	F	Catalysis of the reaction: UDP-D-galactopyranose = UDP-D-galacto-1,4-furanose.
8768	UDP-sugar diphosphatase activity	F	Catalysis of the reaction: UDP-sugar + H2O = UMP + sugar 1-phosphate.
8770	[acyl-carrier-protein] phosphodiesterase activity	F	Catalysis of the reaction: [acyl-carrier protein] + H2O = 4'-phosphopantetheine + apoprotein.
8771	[citrate (pro-3S)-lyase] ligase activity	F	Catalysis of the reaction: ATP + acetate + (citrate (pro-3S)-lyase) (thiol form) = AMP + diphosphate + (citrate (pro-3S)-lyase) (acetyl form).
8772	[isocitrate dehydrogenase (NADP+)] kinase activity	F	Catalysis of the reaction: ATP + (isocitrate dehydrogenase (NADP)) = ADP + (isocitrate dehydrogenase (NADP)) phosphate.
8773	[protein-PII] uridylyltransferase activity	F	Catalysis of the reaction: UTP + (protein-PII) = diphosphate + uridylyl-(protein-PII).
8774	acetaldehyde dehydrogenase (acetylating) activity	F	Catalysis of the reaction: acetaldehyde + CoA + NAD+ = acetyl-CoA + NADH + H+.
8775	acetate CoA-transferase activity	F	Catalysis of the reaction: acyl-CoA + acetate = a fatty acid anion + acetyl-CoA.
8776	acetate kinase activity	F	Catalysis of the reaction: ATP + acetate = ADP + acetyl phosphate.
8777	acetylornithine deacetylase activity	F	Catalysis of the reaction: N2-acetyl-L-ornithine + H2O = acetate + L-ornithine.
8779	acyl-[acyl-carrier-protein]-phospholipid O-acyltransferase activity	F	Catalysis of the reaction: acyl-[acyl-carrier protein] + O-(2-acyl-sn-glycero-3-phospho)ethanolamine = [acyl-carrier protein] + O-(1-beta-acyl-2-acyl-sn-glycero-3-phospho)ethanolamine.
8780	acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity	F	Catalysis of the reaction: (R)-3-hydroxytetradecanoyl-[acyl-carrier protein] + UDP-N-acetylglucosamine = [acyl-carrier protein] + UDP-3-O-(3-hydroxytetradecanoyl)-N-acetylglucosamine.
8781	N-acylneuraminate cytidylyltransferase activity	F	Catalysis of the reaction: CTP + N-acylneuraminate = diphosphate + CMP-N-acylneuraminate.
8782	adenosylhomocysteine nucleosidase activity	F	Catalysis of the reaction: S-adenosyl-L-homocysteine + H2O = adenine + S-D-ribosyl-L-homocysteine.
8783	agmatinase activity	F	Catalysis of the reaction: agmatine + H(2)O = putrescine + urea.
8784	alanine racemase activity	F	Catalysis of the reaction: L-alanine = D-alanine.
8785	alkyl hydroperoxide reductase activity	F	Catalysis of the reaction: octane hydroperoxide + NADH + H+ = H2O + NAD+ + 1-octanol.
8786	allose 6-phosphate isomerase activity	F	Catalysis of the reaction: D-allose-6-phosphate = D-allulose-6-phosphate.
8787	allose kinase activity	F	Catalysis of the reaction: ATP + D-allose = ADP + D-allose 6-phosphate.
8788	alpha,alpha-phosphotrehalase activity	F	Catalysis of the reaction: alpha,alpha-trehalose 6-phosphate + H2O = D-glucose + D-glucose 6-phosphate.
8789	altronate dehydratase activity	F	Catalysis of the reaction: D-altronate = 2-dehydro-3-deoxy-D-gluconate + H(2)O.
8790	arabinose isomerase activity	F	Catalysis of the reaction: D-arabinose = D-ribulose.
8791	arginine N-succinyltransferase activity	F	Catalysis of the reaction: succinyl-CoA + L-arginine = CoA + N2-succinyl-L-arginine.
8792	arginine decarboxylase activity	F	Catalysis of the reaction: L-arginine + H(+) = agmatine + CO(2).
8793	aromatic-amino-acid:2-oxoglutarate aminotransferase activity	F	Catalysis of the reaction: an aromatic amino acid + 2-oxoglutarate = an aromatic oxo acid + L-glutamate.
8794	arsenate reductase (glutaredoxin) activity	F	Catalysis of the reaction: arsenate + reduced glutaredoxin = arsenite + oxidized glutaredoxin. Glutaredoxin functions as the electron donor for arsenate reduction. The electron flow therefore is ( NADPH -> glutathione reductase (EC:1.6.4.2) -> ) glutathione -> glutaredoxin -> arsenate reductase, i.e. glutathione is reduced by glutathione reductase and glutaredoxin is reduced by glutathione.
8795	NAD+ synthase activity	F	Catalysis of the reaction: ATP + deamido-NAD+ + NH3 = AMP + diphosphate + NAD+.
8796	bis(5'-nucleosyl)-tetraphosphatase activity	F	Catalysis of the hydrolysis of P(1),P(4)-bis(5'-nucleosyl)tetraphosphate into two nucleotides.
8797	aspartate ammonia-lyase activity	F	Catalysis of the reaction: L-aspartate = fumarate + NH3.
8798	beta-aspartyl-peptidase activity	F	Catalysis of the cleavage of a beta-linked aspartic residue from the N-terminus of a polypeptide.
8800	beta-lactamase activity	F	Catalysis of the reaction: a beta-lactam + H2O = a substituted beta-amino acid.
8801	beta-phosphoglucomutase activity	F	Catalysis of the reaction: beta-D-glucose 1-phosphate = beta-D-glucose 6-phosphate.
8802	betaine-aldehyde dehydrogenase activity	F	Catalysis of the reaction: betaine aldehyde + NAD+ + H2O = betaine + NADH + H+.
8803	bis(5'-nucleosyl)-tetraphosphatase (symmetrical) activity	F	Catalysis of the reaction: P(1),P(4)-bis(5'-adenosyl) tetraphosphate + H(2)O = 2 ADP + 2 H(+).
8804	carbamate kinase activity	F	Catalysis of the reaction: ATP + NH3 + CO2 = ADP + carbamoyl phosphate.
8805	carbon-monoxide oxygenase activity	F	Catalysis of the reaction: CO + H2O + ferrocytochrome b-561 = CO2 + 2 H+ + 2 ferricytochrome b-561.
8806	carboxymethylenebutenolidase activity	F	Catalysis of the reaction: 4-carboxymethylenebut-2-en-4-olide + H2O = 4 oxohex-2-enedioate.
8807	carboxyvinyl-carboxyphosphonate phosphorylmutase activity	F	Catalysis of the reaction: 1-carboxyvinyl carboxyphosphonate = 3-(hydrohydroxyphosphoryl)pyruvate + CO2.
8808	cardiolipin synthase activity	F	Catalysis of the reaction: phosphatidylglycerol + phosphatidylglycerol = diphosphatidylglycerol (cardiolipin) + glycerol.
8809	carnitine racemase activity	F	Catalysis of the reaction: D-carnitine = L-carnitine.
8810	cellulase activity	F	Catalysis of the endohydrolysis of (1->4)-beta-D-glucosidic linkages in cellulose, lichenin and cereal beta-D-glucans.
8811	chloramphenicol O-acetyltransferase activity	F	Catalysis of the reaction: chloramphenicol + acetyl-CoA = chloramphenicol 3-acetate + CoA.
8812	choline dehydrogenase activity	F	Catalysis of the reaction: A + choline = AH(2) + betaine aldehyde.
8813	chorismate lyase activity	F	Catalysis of the reaction: chorismate = 4-hydroxybenzoate + pyruvate.
8814	citrate CoA-transferase activity	F	Catalysis of the reaction: acetyl-CoA + citrate = acetate + (3S)-citryl-CoA.
8815	citrate (pro-3S)-lyase activity	F	Catalysis of the reaction: citrate = acetate + oxaloacetate.
8816	citryl-CoA lyase activity	F	Catalysis of the reaction: (3S)-citryl-CoA = acetyl-CoA + oxaloacetate.
8817	cob(I)yrinic acid a,c-diamide adenosyltransferase activity	F	Catalysis of the reaction: ATP + cob(I)alamin + H2O = phosphate + diphosphate + adenosylcobalamin.
8818	cobalamin 5'-phosphate synthase activity	F	Catalysis of the reaction: adenosylcobinamide-GDP + alpha-ribazole-5'-phosphate = adenosylcobalamin-5'-phosphate + GMP.
8819	cobinamide kinase activity	F	Catalysis of the reaction: cobinamide + ATP = cobinamide phosphate + ADP. This reaction is the phosphorylation of the hydroxyl group of the 1-amino-2-propanol residue of cobinamide, in the presence of ATP, to form cobinamide phosphate.
8820	cobinamide phosphate guanylyltransferase activity	F	Catalysis of the reaction: adenosylcobinamide phosphate + GTP + 2 H(+) = adenosylcobinamide-GDP + diphosphate.
8821	crossover junction endodeoxyribonuclease activity	F	Catalysis of the endonucleolytic cleavage at a junction such as a reciprocal single-stranded crossover between two homologous DNA duplexes (Holliday junction).
8823	cupric reductase activity	F	Catalysis of the reaction: Cu+ + NAD+ + H+ = Cu2+ + NADH.
8824	cyanate hydratase activity	F	Catalysis of the reaction: cyanate + H2O = carbamate.
8825	cyclopropane-fatty-acyl-phospholipid synthase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + phospholipid olefinic fatty acid = S-adenosyl-L-homocysteine + phospholipid cyclopropane fatty acid.
8826	cysteine sulfinate desulfinase activity	F	Catalysis of the reaction: 3-sulfinoalanine = L-alanine + sulfite.
8827	cytochrome o ubiquinol oxidase activity	F	Catalysis of the reaction: ubiquinol + O2 = ubiquinone + 2 H2O; cytochrome O is the electron acceptor.
8828	dATP pyrophosphohydrolase activity	F	Catalysis of the reaction: deoxy-ATP + H2O = dAMP + diphosphate.
8829	dCTP deaminase activity	F	Catalysis of the reaction: dCTP + H2O = dUTP + NH3.
8830	dTDP-4-dehydrorhamnose 3,5-epimerase activity	F	Catalysis of the reaction: dTDP-4-dehydro-6-deoxy-alpha-D-glucose = dTDP-4-dehydro-6-deoxy-L-mannose.
8831	dTDP-4-dehydrorhamnose reductase activity	F	Catalysis of the reaction: dTDP-6-deoxy-L-mannose + NADP(+) = dTDP-4-dehydro-6-deoxy-L-mannose + H(+) + NADPH.
8832	dGTPase activity	F	Catalysis of the reaction: dGTP + H(2)O = 2'-deoxyguanosine + 2 H(+) + triphosphate.
8833	deoxyribonuclease IV (phage-T4-induced) activity	F	Catalysis of the endonucleolytic cleavage to 5'-phosphooligonucleotide end-products.
8834	di-trans,poly-cis-decaprenylcistransferase activity	F	Catalysis of the reaction: di-trans-poly-cis-decaprenyl diphosphate + isopentenyl diphosphate = diphosphate + di-trans-poly-cis-undecaprenyl diphosphate.
8835	diaminohydroxyphosphoribosylaminopyrimidine deaminase activity	F	Catalysis of the reaction: 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)-pyrimidine + H(2)O + H(+) = 5-amino-6-(5-phosphoribosylamino)uracil + NH(4)(+).
8836	diaminopimelate decarboxylase activity	F	Catalysis of the reaction: meso-2,6-diaminopimelate + H(+) = L-lysine + CO(2).
8837	diaminopimelate epimerase activity	F	Catalysis of the reaction: LL-2,6-diaminopimelate = meso-2,6-diaminopimelate.
8838	diaminopropionate ammonia-lyase activity	F	Catalysis of the reaction: 2,3-diaminopropionate + H2O = pyruvate + 2 NH3.
8839	4-hydroxy-tetrahydrodipicolinate reductase	F	Catalysis of the reaction: (S)-2,3,4,5-tetrahydropyridine-2,6-dicarboxylate + NAD(P)+ + H2O = (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + NAD(P)H + H+.
8840	4-hydroxy-tetrahydrodipicolinate synthase	F	Catalysis of the reaction: pyruvate + L-aspartate-4-semialdehyde = (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + H2O.
8841	dihydrofolate synthase activity	F	Catalysis of the reaction: ATP + dihydropterate + L-glutamate = ADP + phosphate + dihydrofolate.
8842	diphosphate-purine nucleoside kinase activity	F	Catalysis of the reaction: diphosphate + a purine nucleoside = monophosphate + a purine mononucleotide.
8843	endochitinase activity	F	Catalysis of the hydrolysis of nonterminal (1->4)-beta linkages of N-acetyl-D-glucosamine (GlcNAc) polymers of chitin and chitodextrins. Typically, endochitinases cleave randomly within the chitin chain.
8847	Enterobacter ribonuclease activity	F	Catalysis of the endonucleolytic cleavage to 3'-phosphomononucleotides and 3'-phosphooligonucleotides with 2',3'-cyclic phosphate intermediates.
8849	enterochelin esterase activity	F	Catalysis of the reaction: enterobactin + 3 H2O = 3 N-23-dihydroxybenzoyl-L-serine + 3 H+.
8851	ethanolamine ammonia-lyase activity	F	Catalysis of the reaction: ethanolamine = acetaldehyde + NH3.
8852	exodeoxyribonuclease I activity	F	Catalysis of the degradation of single-stranded DNA. It acts progressively in a 3' to 5' direction, releasing 5'-phosphomononucleotides.
8853	exodeoxyribonuclease III activity	F	Catalysis of the degradation of double-stranded DNA. It acts progressively in a 3' to 5' direction, releasing 5'-phosphomononucleotides.
8854	exodeoxyribonuclease V activity	F	Catalysis of the exonucleolytic cleavage (in the presence of ATP) in either 5' to 3' or 3' to 5' direction to yield 5'-phosphooligonucleotides.
8855	exodeoxyribonuclease VII activity	F	Catalysis of the exonucleolytic cleavage in either 5' to 3' or 3' to 5' direction to yield 5'-phosphomononucleotides.
8856	exodeoxyribonuclease X activity	F	Catalysis of the endonucleolytic cleavage of supercoiled plasma DNA to linear DNA duplexes.
8859	exoribonuclease II activity	F	Catalysis of the reaction: RNA + H2O = 5'-phosphomononucleotides. Cleaves RNA in the 3' to 5' direction.
8860	ferredoxin-NAD+ reductase activity	F	Catalysis of the reaction: reduced ferredoxin + NAD+ = oxidized ferredoxin + NADH + H+.
8861	formate C-acetyltransferase activity	F	Catalysis of the reaction: acetyl-CoA + formate = CoA + pyruvate.
8863	formate dehydrogenase (NAD+) activity	F	Catalysis of the reaction: formate + NAD(+) = CO(2) + NADH.
8864	formyltetrahydrofolate deformylase activity	F	Catalysis of the reaction: 10-formyltetrahydrofolate + H(2)O = (6S)-5,6,7,8-tetrahydrofolate + formate + H(+).
8865	fructokinase activity	F	Catalysis of the reaction: ATP + D-fructose = ADP + D-fructose 6-phosphate.
8866	fructuronate reductase activity	F	Catalysis of the reaction: D-mannonate + NAD(+) = D-fructuronate + H(+) + NADH.
8867	galactarate dehydratase activity	F	Catalysis of the reaction: galactarate = 5-dehydro-4-deoxy-D-glucarate + H(2)O.
8868	galactitol-1-phosphate 5-dehydrogenase activity	F	Catalysis of the reaction: galactitol-1-phosphate + NAD+ = L-tagatose 6-phosphate + NADH + H+.
8869	galactonate dehydratase activity	F	Catalysis of the reaction: D-galactonate = 2-dehydro-3-deoxy-D-galactonate + H(2)O.
8870	galactoside O-acetyltransferase activity	F	Catalysis of the reaction: acetyl-CoA + a beta-D-galactoside = CoA + a 6-acetyl-beta-D-galactoside.
8871	aminoglycoside 2''-nucleotidyltransferase activity	F	Catalysis of the reaction: nucleoside triphosphate + aminoglycoside = diphosphate + 2''-nucleotidylaminoglycoside.
8872	glucarate dehydratase activity	F	Catalysis of the reaction: D-glucarate = 5-dehydro-4-deoxy-D-glucarate + H2O.
8873	gluconate 2-dehydrogenase activity	F	Catalysis of the reaction: D-gluconate + NADP+ = 2-dehydro-D-gluconate + NADPH + H+.
8874	gluconate 5-dehydrogenase activity	F	Catalysis of the reaction: D-gluconate + NADP+ = 5-dehydro-D-gluconate + NADPH + H+.
8875	gluconate dehydrogenase activity	F	Catalysis of the reaction: D-gluconate + NADP+ = dehydro-D-gluconate + NADPH + H+.
8876	quinoprotein glucose dehydrogenase activity	F	Catalysis of the reaction: D-glucose + ubiquinone = D-glucono-1,5-lactone + ubiquinol.
8877	glucose-1-phosphatase activity	F	Catalysis of the reaction: alpha-D-glucose 1-phosphate + H2O = D-glucose + phosphate.
8878	glucose-1-phosphate adenylyltransferase activity	F	Catalysis of the reaction: alpha-D-glucose 1-phosphate + ATP = ADP-glucose + diphosphate.
8879	glucose-1-phosphate thymidylyltransferase activity	F	Catalysis of the reaction: alpha-D-glucose 1-phosphate + dTTP = diphosphate + dTDP-glucose.
8880	glucuronate isomerase activity	F	Catalysis of the reaction: D-glucuronate = D-fructuronate.
8881	glutamate racemase activity	F	Catalysis of the reaction: L-glutamate = D-glutamate.
8882	[glutamate-ammonia-ligase] adenylyltransferase activity	F	Catalysis of the reaction: ATP + [L-glutamate:ammonia ligase (ADP-forming)] = diphosphate + adenylyl-[L-glutamate:ammonia ligase (ADP-forming)].
8883	glutamyl-tRNA reductase activity	F	Catalysis of the reaction: (S)-4-amino-5-oxopentanoate + NADP(+) + tRNA(Glu) = L-glutamyl-tRNA(Glu) + H(+) + NADPH.
8884	glutathionylspermidine amidase activity	F	Catalysis of the reaction: N1-(gamma-L-glutamyl-L-cysteinyl-glycyl)-spermidine + H2O = gamma-L-glutamyl-L-cysteinyl-glycine + spermidine.
8885	glutathionylspermidine synthase activity	F	Catalysis of the reaction: gamma-L-glutamyl-L-cysteinyl-glycine + spermidine + ATP = N1-(gamma-L-glutamyl-L-cysteinyl-glycyl)-spermidine + ADP + phosphate.
8886	glyceraldehyde-3-phosphate dehydrogenase (NADP+) (non-phosphorylating) activity	F	Catalysis of the reaction: D-glyceraldehyde 3-phosphate + H(2)O + NADP(+) = 3-phospho-D-glycerate + 2 H(+) + NADPH.
8887	glycerate kinase activity	F	Catalysis of the reaction: D-glycerate + ATP = 3-phospho-D-glycerate + ADP + 2 H(+).
8888	glycerol dehydrogenase [NAD+] activity	F	Catalysis of the reaction: glycerol + NAD(+) = glycerone + H(+) + NADH.
8889	glycerophosphodiester phosphodiesterase activity	F	Catalysis of the reaction: a glycerophosphodiester + H2O = an alcohol + sn-glycerol 3-phosphate.
8890	glycine C-acetyltransferase activity	F	Catalysis of the reaction: acetyl-CoA + glycine = L-2-amino-3-oxobutanoate + CoA + H(+).
8891	glycolate oxidase activity	F	Catalysis of the reaction: glycolate + O2 = glyoxylate + hydrogen peroxide.
8892	guanine deaminase activity	F	Catalysis of the reaction: guanine + H2O = xanthine + NH3.
8893	guanosine-3',5'-bis(diphosphate) 3'-diphosphatase activity	F	Catalysis of the reaction: guanosine 3',5'-bis(diphosphate) + H2O = guanosine 5'-diphosphate + diphosphate.
8894	guanosine-5'-triphosphate,3'-diphosphate diphosphatase activity	F	Catalysis of the reaction: guanosine 5'-triphosphate,3'-diphosphate + H2O = guanosine 5'-diphosphate,3'-diphosphate + phosphate.
8897	holo-[acyl-carrier-protein] synthase activity	F	Catalysis of the reaction: CoA + substrate-serine = adenosine 3',5'-bisphosphate + substrate-serine-4'-phosphopantetheine. The transfer of the 4'-phosphopantetheine (Ppant) co-factor from coenzyme A to the hydroxyl side chain of the serine residue of acyl- or peptidyl-carrier protein (ACP or PCP) to convert them from the apo to the holo form.
8898	S-adenosylmethionine-homocysteine S-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + L-homocysteine = S-adenosyl-L-homocysteine + L-methionine.
8899	homoserine O-succinyltransferase activity	F	Catalysis of the reaction: L-homoserine + succinyl-CoA = O-succinyl-L-homoserine + CoA.
8900	hydrogen:potassium-exchanging ATPase activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + H+(in) + K+(out) = ADP + phosphate + H+(out) + K+(in).
8901	ferredoxin hydrogenase activity	F	Catalysis of the reaction: 2 reduced ferredoxin + 2 H+ = 2 oxidized ferredoxin + H2.
8902	hydroxymethylpyrimidine kinase activity	F	Catalysis of the reaction: 4-amino-5-hydroxymethyl-2-methylpyrimidine + ATP = 4-amino-2-methyl-5-phosphomethylpyrimidine + ADP + 2 H(+).
8903	hydroxypyruvate isomerase activity	F	Catalysis of the reaction: 3-hydroxypyruvate = 2-hydroxy-3-oxopropanoate.
8904	hygromycin-B 7''-O-phosphotransferase activity	F	Catalysis of the reaction: ATP + hygromycin B = 7''-O-phosphohygromycin B + ADP + 2 H(+).
8905	mannose-phosphate guanylyltransferase activity	F	Catalysis of the transfer of a phosphate group from GTP or GDP to a mannose molecule.
8906	inosine kinase activity	F	Catalysis of the reaction: ATP + inosine = ADP + IMP.
8907	integrase activity	F	Catalysis of the integration of one segment of DNA into another.
8908	isochorismatase activity	F	Catalysis of the reaction: H(2)O + isochorismate = 2,3-dihydroxy-2,3-dihydrobenzoate + pyruvate.
8909	isochorismate synthase activity	F	Catalysis of the reaction: chorismate = isochorismate.
8910	kanamycin kinase activity	F	Catalysis of the reaction: ATP + kanamycin = ADP + 2 H(+) + kanamycin 3'-phosphate.
8911	lactaldehyde dehydrogenase activity	F	Catalysis of the reaction: (S)-lactaldehyde + NAD+ + H2O = (S)-lactate + NADH + H+.
8912	lactaldehyde reductase activity	F	Catalysis of the reaction: propane-1,2-diol + NAD+ = lactaldehyde + NADH + H+.
8913	lauroyltransferase activity	F	Catalysis of the transfer of a lauroyl (dodecanoyl) group from one compound to another.
8914	leucyltransferase activity	F	Catalysis of the reaction: L-leucyl-tRNA + protein = tRNA + L-leucyl-protein.
8915	lipid-A-disaccharide synthase activity	F	Catalysis of the reaction: 2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate + UDP-2,3-bis(3-hydroxytetradecanoyl)-D-glucosamine = 2,3-bis(3-hydroxytetradecanoyl)-D-glucosaminyl-(1->6)-beta-D-2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate + H(+) + UDP.
8917	lipopolysaccharide N-acetylglucosaminyltransferase activity	F	Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + lipopolysaccharide = UDP + N-acetyl-D-glucosaminyl-lipopolysaccharide.
8918	lipopolysaccharide 3-alpha-galactosyltransferase activity	F	Catalysis of the reaction: UDP-galactose + lipopolysaccharide = UDP + 1,3 alpha-D-galactosyl-lipopolysaccharide.
8919	lipopolysaccharide glucosyltransferase I activity	F	Catalysis of the reaction: UDP-glucose + lipopolysaccharide = UDP + D-glucosyl-lipopolysaccharide.
8920	lipopolysaccharide heptosyltransferase activity	F	Catalysis of the reaction: a lipopolysaccharide + ADP-L-glycero-beta-D-manno-heptose = a heptosylated lipopolysaccharide + ADP + H+.
8921	lipopolysaccharide-1,6-galactosyltransferase activity	F	Catalysis of the reaction: UDP-galactose + lipopolysaccharide = UDP + 1,6 alpha-D-galactosyl-lipopolysaccharide.
8922	long-chain fatty acid [acyl-carrier-protein] ligase activity	F	Catalysis of the reaction: ATP + an acid + [acyl-carrier protein] = AMP + diphosphate + acyl-[acyl-carrier protein]. A long-chain fatty acid is fatty acid with a chain length between C13 and C22.
8923	lysine decarboxylase activity	F	Catalysis of the reaction: L-lysine + H(+) = cadaverine + CO(2).
8924	malate dehydrogenase (quinone) activity	F	Catalysis of the reaction: (S)-malate + a quinone = oxaloacetate + a quinol.
8925	maltose O-acetyltransferase activity	F	Catalysis of the reaction: acetyl-CoA + maltose = CoA + acetyl-maltose.
8926	mannitol-1-phosphate 5-dehydrogenase activity	F	Catalysis of the reaction: D-mannitol 1-phosphate + NAD+ = D-fructose 6-phosphate + NADH + H+.
8927	mannonate dehydratase activity	F	Catalysis of the reaction: D-mannonate = 2-dehydro-3-deoxy-D-gluconate + H(2)O.
8928	mannose-1-phosphate guanylyltransferase (GDP) activity	F	Catalysis of the reaction: alpha-D-mannose 1-phosphate + GDP + H(+) = GDP-alpha-D-mannose + phosphate.
8929	methylglyoxal synthase activity	F	Catalysis of the reaction: glycerone phosphate = methylglyoxal + phosphate.
8930	methylthioadenosine nucleosidase activity	F	Catalysis of the reaction: methylthioadenosine + H2O = adenine + 5-methylthio-D-ribose.
8932	lytic endotransglycosylase activity	F	Catalysis of the specific cleavage of the beta-(1->4) glycosidic linkage between N-acetylmuramyl and N-acetylglucosaminyl residues in peptidoglycan, with the concomitant formation of 1,6-anhydro-N-acetylmuramyl residues. Acts on linkages within peptidoglycan chains (i.e. not at the ends) to produce shorter strands with 1,6-anhydromuramic acid ends.
8933	lytic transglycosylase activity	F	Catalysis of the specific cleavage of the beta-(1->4) glycosidic linkage between N-acetylmuramyl and N-acetylglucosaminyl residues in peptidoglycan, with the concomitant formation of 1,6-anhydro-N-acetylmuramyl residues.
8934	inositol monophosphate 1-phosphatase activity	F	Catalysis of the reaction: myo-inositol 1-phosphate + H2O = myo-inositol + phosphate.
8935	1,4-dihydroxy-2-naphthoyl-CoA synthase activity	F	Catalysis of the reaction: 4-(2-carboxyphenyl)-4-oxobutanoyl-CoA = 1,4-dihydroxy-2-napthoyl-CoA + H2O.
8936	nicotinamidase activity	F	Catalysis of the reaction: nicotinamide + H2O = nicotinate + NH3.
8937	ferredoxin-NAD(P) reductase activity	F	Catalysis of the reaction: reduced ferredoxin + NAD(P)+ = oxidized ferredoxin + NAD(P)H + H+.
8938	nicotinate N-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine(1+) + nicotinate = N-methylnicotinate + S-adenosyl-L-homocysteine.
8939	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity	F	Catalysis of the reaction: 5,6-dimethylbenzimidazole + nicotinate D-ribonucleotide = alpha-ribazole 5'-phosphate + H(+) + nicotinate.
8940	nitrate reductase activity	F	Catalysis of the reaction: nitrite + acceptor = nitrate + reduced acceptor.
8941	nitric oxide dioxygenase activity	F	Catalysis of the reaction: 2 NO + 2 O2 + NADPH + H+ = 2 nitrate + NADP+.
8942	nitrite reductase [NAD(P)H] activity	F	Catalysis of the reaction: ammonium hydroxide + 3 NAD(P)+ + H2O = nitrite + 3 NAD(P)H + 3 H+.
8946	oligonucleotidase activity	F	Catalysis of the exonucleolytic cleavage of oligonucleotides to yield nucleoside 5'-phosphates.
8948	oxaloacetate decarboxylase activity	F	Catalysis of the reaction: oxaloacetate = pyruvate + CO2.
8949	oxalyl-CoA decarboxylase activity	F	Catalysis of the reaction: H(+) + oxalyl-CoA = CO(2) + formyl-CoA.
8951	palmitoleoyl [acyl-carrier-protein]-dependent acyltransferase activity	F	Catalysis of the reaction: a palmitoleoyl-[acyl-carrier protein] + alpha-KDO-(2->4)-alpha-KDO-(2->6)-lipid IVA = KDO2-(palmitoleoyl)-lipid IVA + a holo-[acyl-carrier protein].
8953	penicillin amidase activity	F	Catalysis of the reaction: penicillin + H2O = a carboxylate + 6-aminopenicillanate.
8955	peptidoglycan glycosyltransferase activity	F	Catalysis of the reaction: [GlcNAc-(1,4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n)-diphosphoundecaprenol + GlcNAc-(1,4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol = [GlcNAc-(1,4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n+1)-diphosphoundecaprenol + undecaprenyl diphosphate.
8957	phenylacetaldehyde dehydrogenase activity	F	Catalysis of the reaction: phenylacetaldehyde + NAD+ + H2O = phenylacetate + NADH + H+.
8959	phosphate acetyltransferase activity	F	Catalysis of the reaction: acetyl-CoA + phosphate = CoA + acetyl phosphate.
8960	phosphatidylglycerol-membrane-oligosaccharide glycerophosphotransferase activity	F	Catalysis of the reaction: phosphatidylglycerol + membrane-derived-oligosaccharide D-glucose = 1,2-diacyl-sn-glycerol + membrane-derived-oligosaccharide 6-(glycerophospho)-D-glucose.
8961	phosphatidylglycerol-prolipoprotein diacylglyceryl transferase activity	F	Catalysis of the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the prospective N-terminal cysteine residue in an unmodified prolipoprotein.
8962	phosphatidylglycerophosphatase activity	F	Catalysis of the reaction: phosphatidylglycerophosphate + H2O = phosphatidylglycerol + phosphate.
8963	phospho-N-acetylmuramoyl-pentapeptide-transferase activity	F	Catalysis of the reaction: UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-D-alanyl-D-alanine + undecaprenyl phosphate = UMP + N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-D-alanyl-D-alanine-diphosphoundecaprenol.
8964	phosphoenolpyruvate carboxylase activity	F	Catalysis of the reaction: phosphate + oxaloacetate = phosphoenolpyruvate + HCO3-.
8965	phosphoenolpyruvate-protein phosphotransferase activity	F	Catalysis of the reaction: phosphoenolpyruvate + protein L-histidine = pyruvate + protein N(pi)-phospho-L-histidine.
8966	phosphoglucosamine mutase activity	F	Catalysis of the reaction: alpha-D-glucosamine 1-phosphate = D-glucosamine 6-phosphate.
8967	phosphoglycolate phosphatase activity	F	Catalysis of the reaction: 2-phosphoglycolate + H(2)O = glycolate + phosphate.
8968	D-sedoheptulose 7-phosphate isomerase activity	F	Catalysis of the reaction: D-sedoheptulose-7-phosphate = D-alpha,beta-D-heptose 7-phosphate.
8969	phosphohistidine phosphatase activity	F	Catalysis of the reaction: phosphohistidine + H2O = histidine + phosphate.
8970	phosphatidylcholine 1-acylhydrolase activity	F	Catalysis of the reaction: phosphatidylcholine + H2O = 2-acylglycerophosphocholine + a carboxylate.
8972	phosphomethylpyrimidine kinase activity	F	Catalysis of the reaction: ATP + 4-amino-2-methyl-5-phosphomethylpyrimidine = ADP + 4-amino-2-methyl-5-diphosphomethylpyrimidine.
8973	phosphopentomutase activity	F	Catalysis of the reaction: D-ribose 1-phosphate = D-ribose 5-phosphate.
8974	phosphoribulokinase activity	F	Catalysis of the reaction: D-ribulose 5-phosphate + ATP = D-ribulose 1,5-bisphosphate + ADP + 2 H(+).
8976	polyphosphate kinase activity	F	Catalysis of the reaction: ATP + phosphate(n) = ADP + phosphate(n+1).
8977	prephenate dehydrogenase (NAD+) activity	F	Catalysis of the reaction: NAD(+) + prephenate = (4-hydroxyphenyl)pyruvate + CO(2) + NADH.
8979	prophage integrase activity	F	Catalysis of the integration of prophage DNA into a target DNA molecule, usually a bacterial chromosome, via a sequence-specific recombination event which involves the formation of an intasome, a DNA-protein-complex designed for site-specific recombination of the phage and host DNA.
8980	propionate kinase activity	F	Catalysis of the reaction: ATP + propanoate = ADP + propanoyl phosphate.
8982	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity	F	Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + sugar(out) = protein histidine + sugar phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.
8983	protein-glutamate O-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + protein L-glutamate = S-adenosyl-L-homocysteine + protein L-glutamate 5-methyl ester; this reaction is the methylation of peptidyl-L-glutamate to form peptidyl-L-glutamate 5-methyl ester.
8984	protein-glutamate methylesterase activity	F	Catalysis of the reaction: protein L-glutamate O(5)-methyl ester + H2O = protein L-glutamate + methanol.
8986	pyruvate, water dikinase activity	F	Catalysis of the reaction: ATP + H(2)O + pyruvate = AMP + 3 H(+) + phosphate + phosphoenolpyruvate.
8987	quinolinate synthetase A activity	F	Catalysis of the reaction: iminoaspartate + dihydroxy-acetone-phosphate = quinolinate + 2 H2O + phosphate.
8988	rRNA (adenine-N6-)-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing N6-methyladenine.
8989	rRNA (guanine-N1-)-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing N1-methylguanine.
8990	rRNA (guanine-N2-)-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing N2-methylguanine.
8993	rhamnulokinase activity	F	Catalysis of the reaction: ATP + L-rhamnulose = ADP + L-rhamnulose 1-phosphate.
8994	rhamnulose-1-phosphate aldolase activity	F	Catalysis of the reaction: L-rhamnulose 1-phosphate = glycerone phosphate + (S)-lactaldehyde.
8995	ribonuclease E activity	F	Catalysis of the cleavage of single-stranded RNA that is monophosphorylated at its 5'-end; cleavage occurs predominantly at 5 nucleotides from the 5'-end and in A + U-rich regions, and is blocked by the presence of a 5'-triphosphate group.
8996	ribonuclease G activity	F	Catalysis of the cleavage of single-stranded RNA that is monophosphorylated at its 5'-end; cleavage occurs predominantly at positions 5 and 6 nucleotides from the 5'-end and in A + U-rich regions, and is blocked by the presence of a 5'-triphosphate group.
8997	ribonuclease R activity	F	Catalysis of the reaction: RNA + H2O = 5'-phosphomononucleotides. Cleaves RNA in the 3' to 5' direction, leaving an undigested core of 3-5 nucleotides.
8998	ribonucleoside-triphosphate reductase activity	F	Catalysis of the reaction: 2'-deoxyribonucleoside triphosphate + thioredoxin disulfide + H2O = ribonucleoside triphosphate + thioredoxin.
8999	ribosomal-protein-alanine N-acetyltransferase activity	F	Catalysis of the reaction: acetyl-CoA + ribosomal-protein L-alanine = CoA + ribosomal-protein N-acetyl-L-alanine.
9000	selenocysteine lyase activity	F	Catalysis of the reaction: L-selenocysteine + reduced acceptor = hydrogen selenide + L-alanine + acceptor.
9001	serine O-acetyltransferase activity	F	Catalysis of the reaction: L-serine + acetyl-CoA = O-acetyl-L-serine + CoA.
9002	serine-type D-Ala-D-Ala carboxypeptidase activity	F	Catalysis of the reaction: (Ac)2-L-Lys-D-alanyl-D-alanine + H2O = (Ac)2-L-Lys-D-alanine + D-alanine.
9007	site-specific DNA-methyltransferase (adenine-specific) activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + DNA adenine = S-adenosyl-L-homocysteine + DNA 6-methylaminopurine.
9008	DNA-methyltransferase activity	F	Catalysis of the transfer of a methyl group to a DNA molecule.
9009	site-specific recombinase activity	F	Catalysis of the formation of new phosphodiester bonds between a pair of short, unique DNA target sequences.
9010	sorbitol-6-phosphate 2-dehydrogenase activity	F	Catalysis of the reaction: D-sorbitol 6-phosphate + NAD+ = D-fructose 6-phosphate + NADH + H+.
9011	starch synthase activity	F	Catalysis of the reaction: ADP-glucose + (1,4)-alpha-D-glucosyl(n) = ADP + (1,4)-alpha-D-glucosyl(n+1).
9012	aminoglycoside 3''-adenylyltransferase activity	F	Catalysis of the reaction: ATP + streptomycin = 3''-adenylylstreptomycin + diphosphate + H(+).
9013	succinate-semialdehyde dehydrogenase [NAD(P)+] activity	F	Catalysis of the reaction: succinate semialdehyde + NAD(P)+ + H2O = succinate + NAD(P)H + H+.
9014	succinyl-diaminopimelate desuccinylase activity	F	Catalysis of the reaction: N-succinyl-LL-2,6-diaminopimelate + H(2)O = LL-2,6-diaminopimelate + succinate.
9015	N-succinylarginine dihydrolase activity	F	Catalysis of the reaction: N(2)-succinyl-L-arginine + 2 H(2)O + 2 H(+) = N(2)-succinyl-L-ornithine + CO(2) + 2 NH(4)(+).
9016	succinyldiaminopimelate transaminase activity	F	Catalysis of the reaction: 2-oxoglutarate + N-succinyl-LL-2,6-diaminopimelate = L-2-succinylamino-6-oxopimelate + L-glutamate.
9017	succinylglutamate desuccinylase activity	F	Catalysis of the reaction: N-succinyl-L-glutamate + H(2)O = L-glutamate + succinate.
9018	sucrose phosphorylase activity	F	Catalysis of the reaction: sucrose + phosphate = D-fructose + alpha-D-glucose 1-phosphate.
9019	tRNA (guanine-N1-)-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing N1-methylguanine.
9020	tRNA (guanosine-2'-O-)-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing 2'-O-methylguanosine.
9022	tRNA nucleotidyltransferase activity	F	Catalysis of the reaction: tRNA(n+1) + phosphate = tRNA(n) + a nucleoside diphosphate.
9024	tagatose-6-phosphate kinase activity	F	Catalysis of the reaction: ATP + D-tagatose 6-phosphate = ADP + D-tagatose 1,6-bisphosphate.
9025	tagatose-bisphosphate aldolase activity	F	Catalysis of the reaction: D-tagatose 1,6-diphosphate = D-glyceraldehyde 3-phosphate + glycerone phosphate.
9026	tagaturonate reductase activity	F	Catalysis of the reaction: D-altronate + NAD(+) = D-tagaturonate + H(+) + NADH.
9027	tartrate dehydrogenase activity	F	Catalysis of the reaction: tartrate + NAD+ = oxaloglycolate + NADH + H+.
9028	tartronate-semialdehyde synthase activity	F	Catalysis of the reaction: 2 glyoxylate + H(+) = 2-hydroxy-3-oxopropanoate + CO(2).
9029	tetraacyldisaccharide 4'-kinase activity	F	Catalysis of the reaction: 2,3-bis(3-hydroxytetradecanoyl)-D-glucosaminyl-(1->6)-beta-D-2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate + ATP = ADP + 2 H(+) + lipid IV(a).
9030	thiamine-phosphate kinase activity	F	Catalysis of the reaction: ATP + thiamine phosphate = ADP + H(+) + thiamine diphosphate.
9032	thymidine phosphorylase activity	F	Catalysis of the reaction: thymidine + phosphate = thymine + 2-deoxy-D-ribose 1-phosphate.
9033	trimethylamine-N-oxide reductase activity	F	Catalysis of the reaction: NADH + H+ + trimethylamine-N-oxide = NAD+ + trimethylamine + H2O.
9034	tryptophanase activity	F	Catalysis of the reaction: L-tryptophan + H(2)O = indole + NH(4)(+) + pyruvate.
9035	Type I site-specific deoxyribonuclease activity	F	Catalysis of the endonucleolytic cleavage of DNA to give random double-stranded fragments with terminal 5' or 3' protrusions; ATP is simultaneously hydrolyzed. Cleavage is dependent on the presence in the DNA of a specific recognition site. Cleavage may occur hundreds or thousands of base pairs away from the recognition site due to translocation of DNA.
9036	Type II site-specific deoxyribonuclease activity	F	Catalysis of the endonucleolytic cleavage of DNA to give specific double-stranded fragments with terminal 5'-phosphates and 3' hydroxyls. Cleavage is dependent on the presence in the DNA of a specific recognition site; cleavage occurs at or very near this recognition site.
9037	tyrosine-based site-specific recombinase activity	F	Catalysis of the formation of new phosphodiester bonds between a pair of short, unique DNA target sequences; occurs through a phosphotyrosyl intermediate in which the target sequence is first cleaved by the nucleophilic attack by a tyrosine in the active site.
9038	undecaprenol kinase activity	F	Catalysis of the reaction: ATP + undecaprenol = ADP + undecaprenyl phosphate.
9039	urease activity	F	Catalysis of the reaction: urea + H2O = CO2 + 2 NH3.
9040	ureidoglycolate dehydrogenase activity	F	Catalysis of the reaction: (S)-ureidoglycolate + NAD(P)+ = oxalureate + NAD(P)H + H+.
9041	uridylate kinase activity	F	Catalysis of the reaction: ATP + (d)UMP = ADP + (d)UDP.
9042	valine-pyruvate transaminase activity	F	Catalysis of the reaction: L-valine + pyruvate = 3-methyl-2-oxobutanoate + L-alanine.
9044	xylan 1,4-beta-xylosidase activity	F	Catalysis of the hydrolysis of (1->4)-beta-D-xylans so as to remove successive D-xylose residues from the non-reducing termini.
9045	xylose isomerase activity	F	Catalysis of the reaction: D-xylose = D-xylulose.
9046	zinc D-Ala-D-Ala carboxypeptidase activity	F	Catalysis of the cleavage of the D-alanyl-D-alanine bond in (Ac)2-L-lysyl-D-alanyl-D-alanine.
9047	dosage compensation by hyperactivation of X chromosome	P	Compensating for the two-fold variation in X-chromosome:autosome ratios between sexes by a global hyperactivation of all, or most of, the genes on the X-chromosome in the heterogametic sex, leading to a two-fold increase in gene expression from this chromosome. An example of this is found in Drosophila melanogaster.
9048	dosage compensation by inactivation of X chromosome	P	Compensating for the two-fold variation in X-chromosome:autosome ratios between sexes by a global inactivation of all, or most of, the genes on one of the X-chromosomes in the XX sex.
9050	glycopeptide catabolic process	P	The chemical reactions and pathways resulting in the breakdown of glycopeptides, any compound in which carbohydrate is covalently attached to an oligopeptide composed of residues of L and/or D-amino acids. The term usually denotes a product of proteolytic degradation of a glycoprotein but includes glycated peptide.
9051	pentose-phosphate shunt, oxidative branch	P	The branch of the pentose-phosphate shunt which involves the oxidation of glucose 6-P and produces ribulose 5-P, reduced NADP+ and carbon dioxide (CO2).
9052	pentose-phosphate shunt, non-oxidative branch	P	The branch of the pentose-phosphate shunt which does not involve oxidation reactions. It comprises a series of sugar phosphate interconversions, starting with ribulose 5-P and producing fructose 6-P and glyceraldehyde 3-P.
9055	electron carrier activity	F	Any molecular entity that serves as an electron acceptor and electron donor in an electron transport chain. An electron transport chain is a process in which a series of electron carriers operate together to transfer electrons from donors to any of several different terminal electron acceptors to generate a transmembrane electrochemical gradient.
9056	catabolic process	P	The chemical reactions and pathways resulting in the breakdown of substances, including the breakdown of carbon compounds with the liberation of energy for use by the cell or organism.
9057	macromolecule catabolic process	P	The chemical reactions and pathways resulting in the breakdown of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
9058	biosynthetic process	P	The chemical reactions and pathways resulting in the formation of substances; typically the energy-requiring part of metabolism in which simpler substances are transformed into more complex ones.
9059	macromolecule biosynthetic process	P	The chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
9060	aerobic respiration	P	The enzymatic release of energy from inorganic and organic compounds (especially carbohydrates and fats) which requires oxygen as the terminal electron acceptor.
9061	anaerobic respiration	P	The enzymatic release of energy from inorganic and organic compounds (especially carbohydrates and fats) which uses compounds other than oxygen (e.g. nitrate, sulfate) as the terminal electron acceptor.
9062	fatty acid catabolic process	P	The chemical reactions and pathways resulting in the breakdown of a fatty acid, any of the aliphatic monocarboxylic acids that can be liberated by hydrolysis from naturally occurring fats and oils. Fatty acids are predominantly straight-chain acids of 4 to 24 carbon atoms, which may be saturated or unsaturated; branched fatty acids and hydroxy fatty acids also occur, and very long chain acids of over 30 carbons are found in waxes.
9063	cellular amino acid catabolic process	P	The chemical reactions and pathways resulting in the breakdown of amino acids, organic acids containing one or more amino substituents.
9064	glutamine family amino acid metabolic process	P	The chemical reactions and pathways involving amino acids of the glutamine family, comprising arginine, glutamate, glutamine and proline.
9065	glutamine family amino acid catabolic process	P	The chemical reactions and pathways resulting in the breakdown of amino acids of the glutamine family, comprising arginine, glutamate, glutamine and proline.
9066	aspartate family amino acid metabolic process	P	The chemical reactions and pathways involving amino acids of the aspartate family, comprising asparagine, aspartate, lysine, methionine and threonine.
9067	aspartate family amino acid biosynthetic process	P	The chemical reactions and pathways resulting in the formation of amino acids of the aspartate family, comprising asparagine, aspartate, lysine, methionine and threonine.
9068	aspartate family amino acid catabolic process	P	The chemical reactions and pathways resulting in the breakdown of amino acids of the aspartate family, comprising asparagine, aspartate, lysine, methionine and threonine.
9069	serine family amino acid metabolic process	P	The chemical reactions and pathways involving amino acids of the serine family, comprising cysteine, glycine, homoserine, selenocysteine and serine.
9070	serine family amino acid biosynthetic process	P	The chemical reactions and pathways resulting in the formation of amino acids of the serine family, comprising cysteine, glycine, homoserine, selenocysteine and serine.
9071	serine family amino acid catabolic process	P	The chemical reactions and pathways resulting in the breakdown of amino acids of the serine family, comprising cysteine, glycine, homoserine, selenocysteine and serine.
9072	aromatic amino acid family metabolic process	P	The chemical reactions and pathways involving aromatic amino acid family, amino acids with aromatic ring (phenylalanine, tyrosine, tryptophan).
9073	aromatic amino acid family biosynthetic process	P	The chemical reactions and pathways resulting in the formation of aromatic amino acid family, amino acids with aromatic ring (phenylalanine, tyrosine, tryptophan).
9074	aromatic amino acid family catabolic process	P	The chemical reactions and pathways resulting in the breakdown of aromatic amino acid family, amino acids with aromatic ring (phenylalanine, tyrosine, tryptophan).
9078	pyruvate family amino acid metabolic process	P	The chemical reactions and pathways involving any amino acid that requires pyruvate for its synthesis, e.g. alanine.
9079	pyruvate family amino acid biosynthetic process	P	The chemical reactions and pathways resulting in the formation of any amino acid that requires pyruvate for its synthesis, e.g. alanine.
9080	pyruvate family amino acid catabolic process	P	The chemical reactions and pathways resulting in the breakdown of any amino acid that requires pyruvate for its synthesis, e.g. alanine.
9081	branched-chain amino acid metabolic process	P	The chemical reactions and pathways involving amino acids containing a branched carbon skeleton, comprising isoleucine, leucine and valine.
9082	branched-chain amino acid biosynthetic process	P	The chemical reactions and pathways resulting in the formation of amino acids containing a branched carbon skeleton, comprising isoleucine, leucine and valine.
9083	branched-chain amino acid catabolic process	P	The chemical reactions and pathways resulting in the breakdown of amino acids containing a branched carbon skeleton, comprising isoleucine, leucine and valine.
9084	glutamine family amino acid biosynthetic process	P	The chemical reactions and pathways resulting in the formation of amino acids of the glutamine family, comprising arginine, glutamate, glutamine and proline.
9085	lysine biosynthetic process	P	The chemical reactions and pathways resulting in the formation of lysine, 2,6-diaminohexanoic acid.
9086	methionine biosynthetic process	P	The chemical reactions and pathways resulting in the formation of methionine (2-amino-4-(methylthio)butanoic acid), a sulfur-containing, essential amino acid found in peptide linkage in proteins.
9087	methionine catabolic process	P	The chemical reactions and pathways resulting in the breakdown of methionine (2-amino-4-(methylthio)butanoic acid), a sulfur-containing, essential amino acid found in peptide linkage in proteins.
9088	threonine biosynthetic process	P	The chemical reactions and pathways resulting in the formation of threonine (2-amino-3-hydroxybutyric acid), a polar, uncharged, essential amino acid found in peptide linkage in proteins.
9089	lysine biosynthetic process via diaminopimelate	P	The chemical reactions and pathways resulting in the formation of lysine, via the intermediate diaminopimelate.
9090	homoserine biosynthetic process	P	The chemical reactions and pathways resulting in the formation of homoserine, alpha-amino-gamma-hydroxybutyric acid.
9091	homoserine catabolic process	P	The chemical reactions and pathways resulting in the breakdown of homoserine, alpha-amino-gamma-hydroxybutyric acid.
9092	homoserine metabolic process	P	The chemical reactions and pathways involving homoserine, alpha-amino-gamma-hydroxybutyric acid, an intermediate in the biosynthesis of cystathionine, threonine and methionine.
9093	cysteine catabolic process	P	The chemical reactions and pathways resulting in the breakdown of cysteine, 2-amino-3-mercaptopropanoic acid.
9094	L-phenylalanine biosynthetic process	P	The chemical reactions and pathways resulting in the formation of L-phenylalanine, the L-enantiomer of 2-amino-3-phenylpropanoic acid, i.e. (2S)-2-amino-3-phenylpropanoic acid.
9095	aromatic amino acid family biosynthetic process, prephenate pathway	P	The chemical reactions and pathways resulting in the formation of phenylalanine and tyrosine from other compounds, including chorismate, via the intermediate prephenate.
9097	isoleucine biosynthetic process	P	The chemical reactions and pathways resulting in the formation of isoleucine, (2R*,3R*)-2-amino-3-methylpentanoic acid.
9098	leucine biosynthetic process	P	The chemical reactions and pathways resulting in the formation of leucine, 2-amino-4-methylpentanoic acid.
9099	valine biosynthetic process	P	The chemical reactions and pathways resulting in the formation of valine, 2-amino-3-methylbutanoic acid.
9100	glycoprotein metabolic process	P	The chemical reactions and pathways involving glycoproteins, any protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide.
9101	glycoprotein biosynthetic process	P	The chemical reactions and pathways resulting in the formation of glycoproteins, any protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide.
9102	biotin biosynthetic process	P	The chemical reactions and pathways resulting in the formation of biotin, cis-tetrahydro-2-oxothieno(3,4-d)imidazoline-4-valeric acid.
9103	lipopolysaccharide biosynthetic process	P	The chemical reactions and pathways resulting in the formation of lipopolysaccharides, any of a group of related, structurally complex components of the outer membrane of Gram-negative bacteria.
9104	lipopolysaccharide catabolic process	P	The chemical reactions and pathways resulting in the breakdown of lipopolysaccharides, any of a group of related, structurally complex components of the outer membrane of Gram-negative bacteria.
9106	lipoate metabolic process	P	The chemical reactions and pathways involving lipoate, 1,2-dithiolane-3-pentanoate, the anion derived from lipoic acid.
9107	lipoate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of lipoate, 1,2-dithiolane-3-pentanoate, the anion derived from lipoic acid.
9108	coenzyme biosynthetic process	P	The chemical reactions and pathways resulting in the formation of coenzymes, any of various nonprotein organic cofactors that are required, in addition to an enzyme and a substrate, for an enzymatic reaction to proceed.
9109	coenzyme catabolic process	P	The chemical reactions and pathways resulting in the breakdown of coenzymes, any of various nonprotein organic cofactors that are required, in addition to an enzyme and a substrate, for an enzymatic reaction to proceed.
9110	vitamin biosynthetic process	P	The chemical reactions and pathways resulting in the formation of a vitamin, one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body.
9111	vitamin catabolic process	P	The chemical reactions and pathways resulting in the breakdown of a vitamin, one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body.
9112	nucleobase metabolic process	P	The chemical reactions and pathways involving a nucleobase, a nitrogenous base that is a constituent of a nucleic acid, e.g. the purines: adenine, guanine, hypoxanthine, xanthine and the pyrimidines: cytosine, uracil, thymine.
9113	purine nucleobase biosynthetic process	P	The chemical reactions and pathways resulting in the formation of purine nucleobases, one of the two classes of nitrogen-containing ring compounds found in DNA and RNA, which include adenine and guanine.
9114	hypoxanthine catabolic process	P	The chemical reactions and pathways resulting in the breakdown of hypoxanthine, 6-hydroxy purine, an intermediate in the degradation of adenylate. Its ribonucleoside is known as inosine and its ribonucleotide as inosinate.
9115	xanthine catabolic process	P	The chemical reactions and pathways resulting in the breakdown of xanthine, 2,6-dihydroxypurine, a purine formed in the metabolic breakdown of guanine but not present in nucleic acids.
9116	nucleoside metabolic process	P	The chemical reactions and pathways involving a nucleoside, a nucleobase linked to either beta-D-ribofuranose (a ribonucleoside) or 2-deoxy-beta-D-ribofuranose, (a deoxyribonucleoside), e.g. adenosine, guanosine, inosine, cytidine, uridine and deoxyadenosine, deoxyguanosine, deoxycytidine and thymidine (= deoxythymidine).
9117	nucleotide metabolic process	P	The chemical reactions and pathways involving a nucleotide, a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the glycose moiety; may be mono-, di- or triphosphate; this definition includes cyclic nucleotides (nucleoside cyclic phosphates).
9118	regulation of nucleoside metabolic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nucleosides.
9119	ribonucleoside metabolic process	P	The chemical reactions and pathways involving any ribonucleoside, a nucleoside in which purine or pyrimidine base is linked to a ribose (beta-D-ribofuranose) molecule.
9120	deoxyribonucleoside metabolic process	P	The chemical reactions and pathways involving any one of a family of organic molecules consisting of a purine or pyrimidine base covalently bonded to a sugar deoxyribose (a deoxyribonucleoside).
9123	nucleoside monophosphate metabolic process	P	The chemical reactions and pathways involving a nucleoside monophosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with phosphate on the sugar.
9124	nucleoside monophosphate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of a nucleoside monophosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with phosphate on the sugar.
9125	nucleoside monophosphate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of a nucleoside monophosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with phosphate on the sugar.
9126	purine nucleoside monophosphate metabolic process	P	The chemical reactions and pathways involving purine nucleoside monophosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with phosphate on the sugar.
9127	purine nucleoside monophosphate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of purine nucleoside monophosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with phosphate on the sugar.
9128	purine nucleoside monophosphate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of purine nucleoside monophosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with phosphate on the sugar.
9129	pyrimidine nucleoside monophosphate metabolic process	P	The chemical reactions and pathways involving pyrimidine nucleoside monophosphate, a compound consisting of a pyrimidine base linked to a ribose or deoxyribose sugar esterified with phosphate on the sugar.
9130	pyrimidine nucleoside monophosphate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of pyrimidine nucleoside monophosphate, a compound consisting of a pyrimidine base linked to a ribose or deoxyribose sugar esterified with phosphate on the sugar.
9131	pyrimidine nucleoside monophosphate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of pyrimidine nucleoside monophosphate, a compound consisting of a pyrimidine base linked to a ribose or deoxyribose sugar esterified with phosphate on the sugar.
9132	nucleoside diphosphate metabolic process	P	The chemical reactions and pathways involving a nucleoside diphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with diphosphate on the sugar.
9133	nucleoside diphosphate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of a nucleoside diphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with diphosphate on the sugar.
9134	nucleoside diphosphate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of a nucleoside diphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with diphosphate on the sugar.
9135	purine nucleoside diphosphate metabolic process	P	The chemical reactions and pathways involving purine nucleoside diphosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with diphosphate on the sugar.
9136	purine nucleoside diphosphate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of purine nucleoside diphosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with diphosphate on the sugar.
9137	purine nucleoside diphosphate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of purine nucleoside diphosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with diphosphate on the sugar.
9138	pyrimidine nucleoside diphosphate metabolic process	P	The chemical reactions and pathways involving pyrimidine nucleoside diphosphate, a compound consisting of a pyrimidine base linked to a ribose or deoxyribose sugar esterified with diphosphate on the sugar.
9139	pyrimidine nucleoside diphosphate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of pyrimidine nucleoside diphosphate, a compound consisting of a pyrimidine base linked to a ribose or deoxyribose sugar esterified with diphosphate on the sugar.
9140	pyrimidine nucleoside diphosphate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of pyrimidine nucleoside diphosphate, a compound consisting of a pyrimidine base linked to a ribose or deoxyribose sugar esterified with diphosphate on the sugar.
9141	nucleoside triphosphate metabolic process	P	The chemical reactions and pathways involving a nucleoside triphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with triphosphate on the sugar.
9142	nucleoside triphosphate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of a nucleoside triphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with triphosphate on the sugar.
9143	nucleoside triphosphate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of a nucleoside triphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with triphosphate on the sugar.
9144	purine nucleoside triphosphate metabolic process	P	The chemical reactions and pathways involving purine nucleoside triphosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with triphosphate on the sugar.
9145	purine nucleoside triphosphate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of purine nucleoside triphosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with triphosphate on the sugar.
9146	purine nucleoside triphosphate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of purine nucleoside triphosphate, a compound consisting of a purine base linked to a ribose or deoxyribose sugar esterified with triphosphate on the sugar.
9147	pyrimidine nucleoside triphosphate metabolic process	P	The chemical reactions and pathways involving pyrimidine nucleoside triphosphate, a compound consisting of a pyrimidine base linked to a ribose or deoxyribose sugar esterified with triphosphate on the sugar.
9148	pyrimidine nucleoside triphosphate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of pyrimidine nucleoside triphosphate, a compound consisting of a pyrimidine base linked to a ribose or deoxyribose sugar esterified with triphosphate on the sugar.
9149	pyrimidine nucleoside triphosphate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of pyrimidine nucleoside triphosphate, a compound consisting of a pyrimidine base linked to a ribose or deoxyribose sugar esterified with triphosphate on the sugar.
9150	purine ribonucleotide metabolic process	P	The chemical reactions and pathways involving a purine ribonucleotide, a compound consisting of ribonucleoside (a purine base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.
9151	purine deoxyribonucleotide metabolic process	P	The chemical reactions and pathways involving purine deoxyribonucleotide, a compound consisting of deoxyribonucleoside (a purine base linked to a deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.
9152	purine ribonucleotide biosynthetic process	P	The chemical reactions and pathways resulting in the formation of a purine ribonucleotide, a compound consisting of ribonucleoside (a purine base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.
9153	purine deoxyribonucleotide biosynthetic process	P	The chemical reactions and pathways resulting in the formation of purine deoxyribonucleotide, a compound consisting of deoxyribonucleoside (a purine base linked to a deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.
9154	purine ribonucleotide catabolic process	P	The chemical reactions and pathways resulting in the breakdown of a purine ribonucleotide, a compound consisting of ribonucleoside (a purine base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.
9155	purine deoxyribonucleotide catabolic process	P	The chemical reactions and pathways resulting in the breakdown of purine deoxyribonucleotide, a compound consisting of deoxyribonucleoside (a purine base linked to a deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.
9156	ribonucleoside monophosphate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of a ribonucleoside monophosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with phosphate on the sugar.
9157	deoxyribonucleoside monophosphate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of a deoxyribonucleoside monophosphate, a compound consisting of a nucleobase linked to a deoxyribose sugar esterified with phosphate on the sugar.
9158	ribonucleoside monophosphate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of a ribonucleoside monophosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with phosphate on the sugar.
9159	deoxyribonucleoside monophosphate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of a deoxyribonucleoside monophosphate, a compound consisting of a nucleobase linked to a deoxyribose sugar esterified with phosphate on the sugar.
9161	ribonucleoside monophosphate metabolic process	P	The chemical reactions and pathways involving a ribonucleoside monophosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with phosphate on the sugar.
9162	deoxyribonucleoside monophosphate metabolic process	P	The chemical reactions and pathways involving a deoxyribonucleoside monophosphate, a compound consisting of a nucleobase linked to a deoxyribose sugar esterified with phosphate on the sugar.
9163	nucleoside biosynthetic process	P	The chemical reactions and pathways resulting in the formation of any one of a family of organic molecules consisting of a purine or pyrimidine base covalently bonded to a sugar ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside).
9164	nucleoside catabolic process	P	The chemical reactions and pathways resulting in the breakdown of any one of a family of organic molecules consisting of a purine or pyrimidine base covalently bonded to a sugar ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside).
9165	nucleotide biosynthetic process	P	The chemical reactions and pathways resulting in the formation of nucleotides, any nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the glycose moiety; may be mono-, di- or triphosphate; this definition includes cyclic-nucleotides (nucleoside cyclic phosphates).
9166	nucleotide catabolic process	P	The chemical reactions and pathways resulting in the breakdown of nucleotides, any nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the glycose moiety; may be mono-, di- or triphosphate; this definition includes cyclic-nucleotides (nucleoside cyclic phosphates).
9167	purine ribonucleoside monophosphate metabolic process	P	The chemical reactions and pathways involving purine ribonucleoside monophosphate, a compound consisting of a purine base linked to a ribose sugar esterified with phosphate on the sugar.
9168	purine ribonucleoside monophosphate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of purine ribonucleoside monophosphate, a compound consisting of a purine base linked to a ribose sugar esterified with phosphate on the sugar.
9169	purine ribonucleoside monophosphate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of purine ribonucleoside monophosphate, a compound consisting of a purine base linked to a ribose sugar esterified with phosphate on the sugar.
9170	purine deoxyribonucleoside monophosphate metabolic process	P	The chemical reactions and pathways involving purine deoxyribonucleoside monophosphate, a compound consisting of a purine base linked to a deoxyribose sugar esterified with phosphate on the sugar.
9171	purine deoxyribonucleoside monophosphate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of purine deoxyribonucleoside monophosphate, a compound consisting of a purine base linked to a deoxyribose sugar esterified with phosphate on the sugar.
9172	purine deoxyribonucleoside monophosphate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of purine deoxyribonucleoside monophosphate, a compound consisting of a purine base linked to a deoxyribose sugar esterified with phosphate on the sugar.
9173	pyrimidine ribonucleoside monophosphate metabolic process	P	The chemical reactions and pathways involving pyrimidine ribonucleoside monophosphate, a compound consisting of a pyrimidine base linked to a ribose sugar esterified with phosphate on the sugar.
9174	pyrimidine ribonucleoside monophosphate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of pyrimidine ribonucleoside monophosphate, a compound consisting of a pyrimidine base linked to a ribose sugar esterified with phosphate on the sugar.
9175	pyrimidine ribonucleoside monophosphate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of pyrimidine ribonucleoside monophosphate, a compound consisting of a pyrimidine base linked to a ribose sugar esterified with phosphate on the sugar.
9176	pyrimidine deoxyribonucleoside monophosphate metabolic process	P	The chemical reactions and pathways involving pyrimidine deoxynucleoside monophosphate, a compound consisting of a pyrimidine base linked to a deoxyribose sugar esterified with phosphate on the sugar.
9177	pyrimidine deoxyribonucleoside monophosphate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of pyrimidine deoxynucleoside monophosphate, a compound consisting of a pyrimidine base linked to a deoxyribose sugar esterified with phosphate on the sugar.
9178	pyrimidine deoxyribonucleoside monophosphate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of pyrimidine deoxynucleoside monophosphate, a compound consisting of a pyrimidine base linked to a deoxyribose sugar esterified with phosphate on the sugar.
9179	purine ribonucleoside diphosphate metabolic process	P	The chemical reactions and pathways involving purine ribonucleoside diphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with diphosphate on the sugar.
9180	purine ribonucleoside diphosphate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of purine ribonucleoside diphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with diphosphate on the sugar.
9181	purine ribonucleoside diphosphate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of purine ribonucleoside diphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with diphosphate on the sugar.
9182	purine deoxyribonucleoside diphosphate metabolic process	P	The chemical reactions and pathways involving purine deoxyribonucleoside diphosphate, a compound consisting of a purine base linked to a deoxyribose sugar esterified with diphosphate on the sugar.
9183	purine deoxyribonucleoside diphosphate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of purine deoxyribonucleoside diphosphate, a compound consisting of a purine base linked to a deoxyribose sugar esterified with diphosphate on the sugar.
9184	purine deoxyribonucleoside diphosphate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of purine deoxyribonucleoside diphosphate, a compound consisting of a purine base linked to a deoxyribose sugar esterified with diphosphate on the sugar.
9185	ribonucleoside diphosphate metabolic process	P	The chemical reactions and pathways involving a ribonucleoside diphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with diphosphate on the sugar.
9186	deoxyribonucleoside diphosphate metabolic process	P	The chemical reactions and pathways involving a deoxyribonucleoside diphosphate, a compound consisting of a nucleobase linked to a deoxyribose sugar esterified with diphosphate on the sugar.
9187	cyclic nucleotide metabolic process	P	The chemical reactions and pathways involving a cyclic nucleotide, a nucleotide in which the phosphate group is in diester linkage to two positions on the sugar residue.
9188	ribonucleoside diphosphate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of a ribonucleoside diphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with diphosphate on the sugar.
9189	deoxyribonucleoside diphosphate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of a deoxyribonucleoside diphosphate, a compound consisting of a nucleobase linked to a deoxyribose sugar esterified with diphosphate on the sugar.
9190	cyclic nucleotide biosynthetic process	P	The chemical reactions and pathways resulting in the formation of a cyclic nucleotide, a nucleotide in which the phosphate group is in diester linkage to two positions on the sugar residue.
9191	ribonucleoside diphosphate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of a ribonucleoside diphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with diphosphate on the sugar.
9192	deoxyribonucleoside diphosphate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of a deoxyribonucleoside diphosphate, a compound consisting of a nucleobase linked to a deoxyribose sugar esterified with diphosphate on the sugar.
9193	pyrimidine ribonucleoside diphosphate metabolic process	P	The chemical reactions and pathways involving pyrimidine ribonucleoside diphosphate, a compound consisting of a pyrimidine base linked to a ribose sugar esterified with diphosphate on the sugar.
9194	pyrimidine ribonucleoside diphosphate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of pyrimidine ribonucleoside diphosphate, a compound consisting of a pyrimidine base linked to a ribose sugar esterified with diphosphate on the sugar.
9195	pyrimidine ribonucleoside diphosphate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of pyrimidine ribonucleoside diphosphate, a compound consisting of a pyrimidine base linked to a ribose sugar esterified with diphosphate on the sugar.
9196	pyrimidine deoxyribonucleoside diphosphate metabolic process	P	The chemical reactions and pathways involving pyrimidine deoxynucleoside diphosphate, a compound consisting of a pyrimidine base linked to a deoxyribose sugar esterified with diphosphate on the sugar.
9197	pyrimidine deoxyribonucleoside diphosphate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of pyrimidine deoxyribonucleoside diphosphate, a compound consisting of a pyrimidine base linked to a deoxyribose sugar esterified with diphosphate on the sugar.
9198	pyrimidine deoxyribonucleoside diphosphate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of pyrimidine deoxynucleoside diphosphate, a compound consisting of a pyrimidine base linked to a deoxyribose sugar esterified with diphosphate on the sugar.
9199	ribonucleoside triphosphate metabolic process	P	The chemical reactions and pathways involving a ribonucleoside triphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with triphosphate on the sugar.
9200	deoxyribonucleoside triphosphate metabolic process	P	The chemical reactions and pathways involving a deoxyribonucleoside triphosphate, a compound consisting of a nucleobase linked to a deoxyribose sugar esterified with triphosphate on the sugar.
9201	ribonucleoside triphosphate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of a ribonucleoside triphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with triphosphate on the sugar.
9202	deoxyribonucleoside triphosphate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of a deoxyribonucleoside triphosphate, a compound consisting of a nucleobase linked to a deoxyribose sugar esterified with triphosphate on the sugar.
9203	ribonucleoside triphosphate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of a ribonucleoside triphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with triphosphate on the sugar.
9204	deoxyribonucleoside triphosphate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of a deoxyribonucleoside triphosphate, a compound consisting of a nucleobase linked to a deoxyribose sugar esterified with triphosphate on the sugar.
9205	purine ribonucleoside triphosphate metabolic process	P	The chemical reactions and pathways involving purine ribonucleoside triphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with triphosphate on the sugar.
9206	purine ribonucleoside triphosphate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of purine ribonucleoside triphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with triphosphate on the sugar.
9207	purine ribonucleoside triphosphate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of purine ribonucleoside triphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with triphosphate on the sugar.
9208	pyrimidine ribonucleoside triphosphate metabolic process	P	The chemical reactions and pathways involving pyrimidine ribonucleoside triphosphate, a compound consisting of a pyrimidine base linked to a ribose sugar esterified with triphosphate on the sugar.
9209	pyrimidine ribonucleoside triphosphate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of pyrimidine ribonucleoside triphosphate, a compound consisting of a pyrimidine base linked to a ribose sugar esterified with triphosphate on the sugar.
9210	pyrimidine ribonucleoside triphosphate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of pyrimidine ribonucleoside triphosphate, a compound consisting of a pyrimidine base linked to a ribose sugar esterified with triphosphate on the sugar.
9211	pyrimidine deoxyribonucleoside triphosphate metabolic process	P	The chemical reactions and pathways involving pyrimidine deoxyribonucleoside triphosphate, a compound consisting of a pyrimidine base linked to a deoxyribose sugar esterified with triphosphate on the sugar.
9212	pyrimidine deoxyribonucleoside triphosphate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of pyrimidine deoxyribonucleoside triphosphate, a compound consisting of a pyrimidine base linked to a deoxyribose sugar esterified with triphosphate on the sugar.
9213	pyrimidine deoxyribonucleoside triphosphate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of pyrimidine deoxyribonucleoside triphosphate, a compound consisting of a pyrimidine base linked to a deoxyribose sugar esterified with triphosphate on the sugar.
9214	cyclic nucleotide catabolic process	P	The chemical reactions and pathways resulting in the breakdown of a cyclic nucleotide, a nucleotide in which the phosphate group is in diester linkage to two positions on the sugar residue.
9215	purine deoxyribonucleoside triphosphate metabolic process	P	The chemical reactions and pathways involving purine deoxyribonucleoside triphosphate, a compound consisting of a purine base linked to a deoxyribose sugar esterified with triphosphate on the sugar.
9216	purine deoxyribonucleoside triphosphate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of purine deoxyribonucleoside triphosphate, a compound consisting of a purine base linked to a deoxyribose sugar esterified with triphosphate on the sugar.
9217	purine deoxyribonucleoside triphosphate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of purine deoxyribonucleoside triphosphate, a compound consisting of a purine base linked to a deoxyribose sugar esterified with triphosphate on the sugar.
9218	pyrimidine ribonucleotide metabolic process	P	The chemical reactions and pathways involving a pyrimidine ribonucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.
9219	pyrimidine deoxyribonucleotide metabolic process	P	The chemical reactions and pathways involving a pyrimidine deoxynucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.
9220	pyrimidine ribonucleotide biosynthetic process	P	The chemical reactions and pathways resulting in the formation of a pyrimidine ribonucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.
9221	pyrimidine deoxyribonucleotide biosynthetic process	P	The chemical reactions and pathways resulting in the formation of a pyrimidine deoxyribonucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.
9222	pyrimidine ribonucleotide catabolic process	P	The chemical reactions and pathways resulting in the breakdown of a pyrimidine ribonucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.
9223	pyrimidine deoxyribonucleotide catabolic process	P	The chemical reactions and pathways resulting in the breakdown of a pyrimidine deoxyribonucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.
9224	CMP biosynthetic process	P	The chemical reactions and pathways resulting in the formation of CMP, cytidine monophosphate.
9225	nucleotide-sugar metabolic process	P	The cellular chemical reactions and pathways involving nucleotide-sugars, any nucleotide-carbohydrate in which the distal phosphoric residue of a nucleoside 5'-diphosphate is in glycosidic linkage with a monosaccharide or monosaccharide derivative.
9226	nucleotide-sugar biosynthetic process	P	The chemical reactions and pathways resulting in the formation of nucleotide-sugars, any nucleotide-carbohydrate in which the distal phosphoric residue of a nucleoside 5'-diphosphate is in glycosidic linkage with a monosaccharide or monosaccharide derivative.
9227	nucleotide-sugar catabolic process	P	The chemical reactions and pathways resulting in the breakdown of nucleotide-sugars, any nucleotide-carbohydrate in which the distal phosphoric residue of a nucleoside 5'-diphosphate is in glycosidic linkage with a monosaccharide or monosaccharide derivative.
9228	thiamine biosynthetic process	P	The chemical reactions and pathways resulting in the formation of thiamine (vitamin B1), a water soluble vitamin present in fresh vegetables and meats, especially liver.
9229	thiamine diphosphate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of thiamine diphosphate, a derivative of thiamine (vitamin B1) which acts as a coenzyme in a range of processes including the Krebs cycle.
9230	thiamine catabolic process	P	The chemical reactions and pathways resulting in the breakdown of thiamine (vitamin B1), a water soluble vitamin present in fresh vegetables and meats, especially liver.
9231	riboflavin biosynthetic process	P	The chemical reactions and pathways resulting in the formation of riboflavin (vitamin B2), the precursor for the coenzymes flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD).
9232	riboflavin catabolic process	P	The chemical reactions and pathways resulting in the breakdown of riboflavin (vitamin B2), the precursor for the coenzymes flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD).
9233	menaquinone metabolic process	P	The chemical reactions and pathways involving any of the menaquinones, quinone-derived compounds synthesized by intestinal bacteria. Structurally, menaquinones consist of a methylated naphthoquinone ring structure and side chains composed of a variable number of unsaturated isoprenoid residues. Menaquinones have vitamin K activity and are known as vitamin K2.
9234	menaquinone biosynthetic process	P	The chemical reactions and pathways resulting in the formation of any of the menaquinones. Structurally, menaquinones consist of a methylated naphthoquinone ring structure and side chains composed of a variable number of unsaturated isoprenoid residues. Menaquinones that have vitamin K activity and are known as vitamin K2.
9235	cobalamin metabolic process	P	The chemical reactions and pathways involving cobalamin (vitamin B12), a water-soluble vitamin characterized by possession of a corrin nucleus containing a cobalt atom.
9236	cobalamin biosynthetic process	P	The chemical reactions and pathways resulting in the formation of cobalamin (vitamin B12), a water-soluble vitamin characterized by possession of a corrin nucleus containing a cobalt atom.
9237	siderophore metabolic process	P	The chemical reactions and pathways involving siderophores, low molecular weight Fe(III)-chelating substances made by aerobic or facultatively anaerobic bacteria, especially when growing under iron deficient conditions. The complexes of Fe(3+)-siderophores have very high stability constants and are taken up by specific transport systems by microorganisms; the subsequent release of iron requires enzymatic action.
9238	enterobactin metabolic process	P	The chemical reactions and pathways involving enterobactin, a catechol-derived siderochrome of Enterobacteria; enterobactin (N',N',N''-(2,6,10-trioxo-1,5,9-triacyclodecane-3,7,11-triyl)tris(2,3-dihydroxy)benzamide) is a self-triester of 2,3-dihydroxy-N-benzoyl-L-serine and a product of the shikimate pathway.
9239	enterobactin biosynthetic process	P	The chemical reactions and pathways resulting in the formation of enterobactin, a catechol-derived siderochrome of Enterobacteria; enterobactin (N',N',N''-(2,6,10-trioxo-1,5,9-triacyclodecane-3,7,11-triyl)tris(2,3-dihydroxy)benzamide) is a self-triester of 2,3-dihydroxy-N-benzoyl-L-serine and a product of the shikimate pathway.
9240	isopentenyl diphosphate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of isopentenyl diphosphate, an isomer of dimethylallyl diphosphate and the key precursor of all isoprenoids.
9242	colanic acid biosynthetic process	P	The chemical reactions and pathways resulting in the formation of colanic acid, a capsular bacterial polysaccharide.
9243	O antigen biosynthetic process	P	The chemical reactions and pathways resulting in the formation of the O side chain of a lipopolysaccharide, which determines the antigenic specificity of the organism. It is made up of about 50 repeating units of a branched tetrasaccharide.
9244	lipopolysaccharide core region biosynthetic process	P	The chemical reactions and pathways resulting in the formation of the core region of bacterial lipopolysaccharides, which contains ten saccharide residues.
9245	lipid A biosynthetic process	P	The chemical reactions and pathways resulting in the formation of lipid A, the glycolipid group of bacterial lipopolysaccharides, consisting of six fatty acyl chains linked to two glucosamine residues.
9246	enterobacterial common antigen biosynthetic process	P	The chemical reactions and pathways resulting in the formation of the enterobacterial common antigen, an acidic polysaccharide containing N-acetyl-D-glucosamine, N-acetyl-D-mannosaminouronic acid, and 4-acetamido-4,6-dideoxy-D-galactose. A major component of the cell wall outer membrane of Gram-negative bacteria.
9247	glycolipid biosynthetic process	P	The chemical reactions and pathways resulting in the formation of glycolipid, a class of 1,2-di-O-acylglycerols joined at oxygen 3 by a glycosidic linkage to a carbohydrate part (usually a mono-, di- or tri-saccharide).
9248	K antigen biosynthetic process	P	The chemical reactions and pathways resulting in the formation of a K antigen, a capsular polysaccharide antigen carried on the surface of bacterial capsules that masks somatic (O) antigens.
9249	protein lipoylation	P	The addition of a lipoyl group to an amino acid residue in a protein.
9250	glucan biosynthetic process	P	The chemical reactions and pathways resulting in the formation of glucans, polysaccharides consisting only of glucose residues.
9251	glucan catabolic process	P	The chemical reactions and pathways resulting in the breakdown of glucans, polysaccharides consisting only of glucose residues.
9252	peptidoglycan biosynthetic process	P	The chemical reactions and pathways resulting in the formation of peptidoglycans, any of a class of glycoconjugates found in bacterial cell walls.
9253	peptidoglycan catabolic process	P	The chemical reactions and pathways resulting in the breakdown of peptidoglycans, any of a class of glycoconjugates found in bacterial cell walls.
9254	peptidoglycan turnover	P	The continual breakdown and regeneration of peptidoglycan required to maintain the cell wall.
9255	Entner-Doudoroff pathway through 6-phosphogluconate	P	A pathway that converts a carbohydrate to pyruvate and glyceraldehyde-3 phosphate by producing 6-phosphogluconate and then dehydrating it.
9256	10-formyltetrahydrofolate metabolic process	P	The chemical reactions and pathways involving 10-formyltetrahydrofolate, the formylated derivative of tetrahydrofolate.
9257	10-formyltetrahydrofolate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of 10-formyltetrahydrofolate, the formylated derivative of tetrahydrofolate.
9258	10-formyltetrahydrofolate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of 10-formyltetrahydrofolate, the formylated derivative of tetrahydrofolate.
9259	ribonucleotide metabolic process	P	The chemical reactions and pathways involving a ribonucleotide, a compound consisting of ribonucleoside (a base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.
9260	ribonucleotide biosynthetic process	P	The chemical reactions and pathways resulting in the formation of a ribonucleotide, a compound consisting of ribonucleoside (a base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.
9261	ribonucleotide catabolic process	P	The chemical reactions and pathways resulting in the breakdown of a ribonucleotide, a compound consisting of ribonucleoside (a base linked to a ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.
9262	deoxyribonucleotide metabolic process	P	The chemical reactions and pathways involving a deoxyribonucleotide, a compound consisting of deoxyribonucleoside (a base linked to a deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.
9263	deoxyribonucleotide biosynthetic process	P	The chemical reactions and pathways resulting in the formation of a deoxyribonucleotide, a compound consisting of deoxyribonucleoside (a base linked to a deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.
9264	deoxyribonucleotide catabolic process	P	The chemical reactions and pathways resulting in the breakdown of a deoxyribonucleotide, a compound consisting of deoxyribonucleoside (a base linked to a deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.
9265	2'-deoxyribonucleotide biosynthetic process	P	The chemical reactions and pathways resulting in the formation of a 2'-deoxyribonucleotide, a compound consisting of 2'-deoxyribonucleoside (a base linked to a 2'-deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.
9266	response to temperature stimulus	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a temperature stimulus.
9267	cellular response to starvation	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of nourishment.
9268	response to pH	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus. pH is a measure of the acidity or basicity of an aqueous solution.
9269	response to desiccation	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a desiccation stimulus, extreme dryness resulting from the prolonged deprivation of water.
9270	response to humidity	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a humidity stimulus, moisture in the atmosphere.
9271	phage shock	P	A response by bacterial cells to a variety of stresses including filamentous phage infection, mislocalization of envelope proteins, extremes of temperature, osmolarity or ethanol concentration, and the presence of proton ionophores such as carbonylcyanide m-chlorophenylhydrazone (CCCP), that involves expression of the phage shock protein operon, and acts to protect the bacterial cells from damage.
9272	fungal-type cell wall biogenesis	P	A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a fungal-type cell wall. The fungal-type cell wall contains beta-glucan and may contain chitin.
9273	peptidoglycan-based cell wall biogenesis	P	The chemical reactions and pathways resulting in the formation of the peptidoglycan-based cell wall. An example of this process is found in Escherichia coli.
9274	peptidoglycan-based cell wall	C	A protective structure outside the cytoplasmic membrane composed of peptidoglycan (also known as murein), a molecule made up of a glycan (sugar) backbone of repetitively alternating N-acetylglucosamine and N-acetylmuramic acid with short, attached, cross-linked peptide chains containing unusual amino acids. An example of this component is found in Escherichia coli.
9275	Gram-positive-bacterium-type cell wall	C	A layer of peptidoglycan found outside of the cytoplasmic membrane. The peptidoglycan is relatively thick (20-80nm) and retains the primary stain of the Gram procedure, thus cells appear blue after Gram stain. The cell walls often contain teichoic acids (acidic anionic polysaccharides) bound to the peptidoglycan. Examples of this component are found in Gram-positive bacteria.
9276	Gram-negative-bacterium-type cell wall	C	The peptidoglycan layer of the Gram-negative cell envelope. In Gram-negative cells the peptidoglycan is relatively thin (1-2nm) and is linked to the outer membrane by lipoproteins. In Gram-negative cells the peptidoglycan is too thin to retain the primary stain in the Gram staining procedure and therefore cells appear red after Gram stain.
9277	fungal-type cell wall	C	A rigid yet dynamic structure surrounding the plasma membrane that affords protection from stresses and contributes to cell morphogenesis, consisting of extensively cross-linked glycoproteins and carbohydrates. The glycoproteins may be modified with N- or O-linked carbohydrates, or glycosylphosphatidylinositol (GPI) anchors; the polysaccharides are primarily branched glucans, including beta-linked and alpha-linked glucans, and may also include chitin and other carbohydrate polymers, but not cellulose or pectin. Enzymes involved in cell wall biosynthesis are also found in the cell wall. Note that some forms of fungi develop a capsule outside of the cell wall under certain circumstances; this is considered a separate structure.
9279	cell outer membrane	C	A lipid bilayer that forms the outermost membrane of the cell envelope; enriched in polysaccharide and protein; the outer leaflet of the membrane contains specific lipopolysaccharide structures.
9288	bacterial-type flagellum	C	A motor complex composed of an extracellular helical protein filament coupled to a rotary motor embedded in the cell envelope.
9289	pilus	C	A proteinaceous hair-like appendage on the surface of bacteria ranging from 2-8 nm in diameter.
9290	DNA import into cell involved in transformation	P	The directed movement of DNA into a cell that contributes to the process of transformation, the uptake of foreign genetic material into a cell.
9291	unidirectional conjugation	P	The process of unidirectional (polarized) transfer of genetic information involving direct cellular contact between a donor and recipient cell; the contact is followed by the formation of a cellular bridge that physically connects the cells; some or all of the chromosome(s) of one cell ('male') is then transferred into the other cell ('female'); unidirectional conjugation occurs between cells of different mating types. Examples of this process are found in Prokaryotes.
9292	genetic transfer	P	In the absence of a sexual life cycle, the process involved in the introduction of genetic information to create a genetically different individual.
9293	transduction	P	The transfer of genetic information to a bacterium from a bacteriophage or between bacterial or yeast cells mediated by a phage vector.
9294	DNA mediated transformation	P	The introduction and uptake of foreign genetic material (DNA or RNA) into a cell, and often the expression of that genetic material.
9295	nucleoid	C	The region of a virus, bacterial cell, mitochondrion or chloroplast to which the nucleic acid is confined.
9297	pilus assembly	P	The assembly of a pilus, a short filamentous structure on a bacterial cell, flagella-like in structure and generally present in many copies. Pili are variously involved in transfer of nucleic acids, adherence to surfaces, and formation of pellicles. Is required for bacterial conjugation, or can play a role in adherence to surfaces (when it is called a fimbrium), and in the formation of pellicles.
9298	GDP-mannose biosynthetic process	P	The chemical reactions and pathways resulting in the formation of GDP-mannose, a substance composed of mannose in glycosidic linkage with guanosine diphosphate.
9299	mRNA transcription	P	The cellular synthesis of messenger RNA (mRNA) from a DNA template.
9300	antisense RNA transcription	P	The synthesis of antisense RNA, an RNA molecule complementary in sequence to another RNA or DNA molecule, which, by binding the latter, acts to inhibit its function and/or completion of synthesis, on a template of DNA.
9301	snRNA transcription	P	The synthesis of small nuclear RNA (snRNA) from a DNA template.
9302	snoRNA transcription	P	The synthesis of small nucleolar RNA (snoRNA) from a DNA template.
9303	rRNA transcription	P	The synthesis of ribosomal RNA (rRNA), any RNA that forms part of the ribosomal structure, from a DNA template.
9304	tRNA transcription	P	The synthesis of transfer RNA (tRNA) from a DNA template.
9305	protein biotinylation	P	The addition of biotin (vitamin B7 / vitamin H) to a protein amino acid.
9306	protein secretion	P	The controlled release of proteins from a cell.
9307	DNA restriction-modification system	P	A defense process found in many bacteria and archaea that protects the organism from invading foreign DNA by cleaving it with a restriction endonuclease. The organism's own DNA is protected by methylation of a specific nucleotide, which occurs immediately following replication, in the same target site as the restriction enzyme.
9308	amine metabolic process	P	The chemical reactions and pathways involving any organic compound that is weakly basic in character and contains an amino or a substituted amino group. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom.
9309	amine biosynthetic process	P	The chemical reactions and pathways resulting in the formation of any organic compound that is weakly basic in character and contains an amino or a substituted amino group. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom.
9310	amine catabolic process	P	The chemical reactions and pathways resulting in the breakdown of any organic compound that is weakly basic in character and contains an amino or a substituted amino group. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom.
9311	oligosaccharide metabolic process	P	The chemical reactions and pathways involving oligosaccharides, molecules with between two and (about) 20 monosaccharide residues connected by glycosidic linkages.
9312	oligosaccharide biosynthetic process	P	The chemical reactions and pathways resulting in the formation of oligosaccharides, molecules with between two and (about) 20 monosaccharide residues connected by glycosidic linkages.
9313	oligosaccharide catabolic process	P	The chemical reactions and pathways resulting in the breakdown of oligosaccharides, molecules with between two and (about) 20 monosaccharide residues connected by glycosidic linkages.
9314	response to radiation	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electromagnetic radiation stimulus. Electromagnetic radiation is a propagating wave in space with electric and magnetic components. These components oscillate at right angles to each other and to the direction of propagation.
9316	3-isopropylmalate dehydratase complex	C	A heterodimeric enzyme complex composed of subunits leuC and leuD. Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.
9317	acetyl-CoA carboxylase complex	C	A protein complex that catalyzes the first step in long-chain fatty acid biosynthesis. For example, in E. coli the complex is heterohexameric and composed of biotin carbonyl carrier protein, biotin carboxylase and the acetate CoA-transferase complex.
9318	exodeoxyribonuclease VII complex	C	An enzyme complex that catalyzes exonucleolytic cleavage in either 5' to 3' or 3' to 5' direction to yield nucleoside 5'-phosphates; it prefers single-stranded DNA.
9319	cytochrome o ubiquinol oxidase complex	C	A protein complex that possesses cytochrome o ubiquinol oxidase activity; consists of four polypeptide subunits and associated prosthetic groups.
9320	phosphoribosylaminoimidazole carboxylase complex	C	A protein complex that possesses phosphoribosylaminoimidazole carboxylase activity.
9321	alkyl hydroperoxide reductase complex	C	An enzyme complex, usually a homodimer, which directly reduces cellular levels of organic hydroperoxides.
9322	trimethylamine-N-oxide reductase complex	C	An enzyme complex that catalyzes the reduction of trimethylamine N-oxide to trimethylamine.
9323	ribosomal-protein-alanine N-acetyltransferase complex	C	An enzyme complex that catalyzes the transfer of an acetyl group to ribosomal-protein alanine, forming ribosomal-protein acetylalanine.
9324	D-amino-acid dehydrogenase complex	C	A protein complex that possesses D-amino-acid dehydrogenase activity.
9325	nitrate reductase complex	C	An enzyme complex that catalyzes the formation of nitrate from nitrite with the concomitant reduction of an acceptor.
9326	formate dehydrogenase complex	C	An enzyme complex that catalyzes the dehydrogenation of formate to produce carbon dioxide (CO2).
9327	NAD(P)+ transhydrogenase complex (AB-specific)	C	A protein complex that possesses NAD(P)+ transhydrogenase (AB-specific) activity. Homodimeric, trimeric, and heterotetrameric complexes have been identified.
9328	phenylalanine-tRNA ligase complex	C	An enzyme complex that catalyzes the ligation of phenylalanine to tRNA(Phe), forming L-phenylalanyl-tRNA(Phe).
9329	acetate CoA-transferase complex	C	A heterotetrameric enzyme complex made up of two alpha subunits and two beta subunits. Part of the acetyl-CoA carboxylase complex. Catalyzes the transfer of a carboxyl group to form malonyl-CoA.
9330	DNA topoisomerase complex (ATP-hydrolyzing)	C	Complex that possesses DNA topoisomerase (ATP-hydrolyzing) activity.
9331	glycerol-3-phosphate dehydrogenase complex	C	An enzyme complex that catalyzes the dehydrogenation of sn-glycerol 3-phosphate to form glycerone phosphate.
9332	glutamate-tRNA ligase complex	C	An enzyme complex that catalyzes the ligation of glutamate and tRNA(Glu) to form glutamyl-tRNA(Glu).
9333	cysteine synthase complex	C	Cysteine synthase is a multienzyme complex made up, in E. coli, of the heteromeric hexamer serine acetyltransferase and the homodimer O-acetylserine (thiol)-lyase A.
9334	3-phenylpropionate dioxygenase complex	C	Enzyme complex consisting of four proteins: the two subunits of the hydroxylase component (hcaE and hcaF), a ferredoxin (hcaC) and a ferredoxin reductase (hcaD). Converts 3-phenylpropionic acid (PP) into cis-3-(3-carboxyethyl)-3,5-cyclohexadiene-1,2-diol (PP-dihydrodiol).
9336	sulfate adenylyltransferase complex (ATP)	C	An enzyme complex that catalyzes the formation adenylylsulfate from sulfate and ATP.
9337	sulfite reductase complex (NADPH)	C	A multisubunit iron flavoprotein, which in yeast is composed of 2 alpha and 2 beta subunits. Catalyzes the reduction of sulfite to sulfide.
9338	exodeoxyribonuclease V complex	C	An enzyme complex that catalyzes exonucleolytic cleavage (in the presence of ATP) in either 5' to 3' or 3' to 5' direction to yield 5'-phosphooligonucleotides. Exodeoxyribonuclease V shows a preference for double-stranded DNA and possesses DNA-dependent ATPase activity. It acts endonucleolytically on single-stranded circular DNA.
9339	glycolate oxidase complex	C	An enzyme complex that catalyzes the oxidation of 2-hydroxy acid to form 2-oxo acid and hydrogen peroxide (H2O2). The enzyme is a flavoprotein (FMN).
9340	DNA topoisomerase IV complex	C	A heterodimeric enzyme, which in most bacterial species is composed of two subunits, ParC and ParE. Functions in chromosome segregation and can relax supercoiled DNA.
9341	beta-galactosidase complex	C	A protein complex that possesses beta-galactosidase activity, i.e. catalyzes the hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D-galactosides. In E. coli, the complex is a homotetramer; dimeric and hexameric beta-galactosidase complexes have been observed in other species.
9342	glutamate synthase complex (NADPH)	C	A complex that possesses glutamate synthase (NADPH) activity.
9343	biotin carboxylase complex	C	An enzyme complex that catalyzes the formation of carboxybiotin-carboxyl-carrier protein from biotin-carboxyl-carrier protein and carbon dioxide (CO2).
9344	nitrite reductase complex [NAD(P)H]	C	Complex that possesses nitrite reductase [NAD(P)H] activity.
9345	glycine-tRNA ligase complex	C	A multimeric enzyme complex which, in bacteria, is usually a tetramer of two alpha and two beta chains and in eukaryotes, is usually a homodimer. Functions in the ligation of glycine and tRNA(Gly) to form glycyl-tRNA(Gly).
9346	citrate lyase complex	C	Citrate lyase is a multienzyme complex with three constituents: the alpha subunit, citrate-ACP transferase; the beta subunit, citryl-ACP lyase; and the gamma subunit, an acyl-carrier protein which also carries the prosthetic group components. All three subunits are required for citrate lyase enzyme activity.
9347	aspartate carbamoyltransferase complex	C	A multienzyme complex that catalyzes the formation N-carbamoyl-L-aspartate from carbamoyl phosphate and L-aspartate. It exhibits a variety of architectural organizations, but in all microorganisms the core catalytic component is a homotrimer of approximately 34 kDa polypeptides.
9348	ornithine carbamoyltransferase complex	C	A homotrimeric protein complex that catalyzes the transfer of a carbamoyl group to ornithine, forming citrulline.
9349	riboflavin synthase complex	C	An flavoprotein that catalyzes the reaction the breakdown of dimethyl(ribityl)lumazine to form riboflavin and ribitylamino-amino-dihydroxypyrimidine.
9350	ethanolamine ammonia-lyase complex	C	An enzyme complex that catalyzes the breakdown of ethanolamine to form acetaldehyde and ammonia.
9353	mitochondrial oxoglutarate dehydrogenase complex	C	A complex of multiple copies of three enzymatic components: oxoglutarate dehydrogenase (lipoamide); EC:1.2.4.2 (E1), dihydrolipoamide S-succinyltransferase; EC:2.3.1.61 (E2) and dihydrolipoamide dehydrogenase; EC:1.8.1.4 (E3); catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and carbon dioxide (CO2) within the mitochondrial matrix. An example of this complex is found in Mus musculus.
9355	DNA polymerase V complex	C	A DNA polymerase complex that contains two UmuD' and one UmuC subunits, and acts in translesion DNA synthesis.
9356	aminodeoxychorismate synthase complex	C	A heterodimeric protein complex that possesses 4-amino-4-deoxychorismate synthase activity.
9357	protein-N(PI)-phosphohistidine-sugar phosphotransferase complex	C	An enzyme complex that catalyzes the transfer of a phosphate from protein N(PI)-phosphohistidine to a sugar molecule. It is enzyme II of the phosphotransferase system.
9358	polyphosphate kinase complex	C	A protein complex that possesses polyphosphate kinase activity.
9359	Type II site-specific deoxyribonuclease complex	C	A protein complex that functions as an endonuclease to cleave DNA at or near a specific recognition site, when that site is unmethylated. These complexes may be dimers or tetramers; it is also possible for the endonuclease to be in a complex with the corresponding methyltransferase that methylates the recognition site. DNA restriction systems such as this are used by bacteria to defend against phage and other foreign DNA that may enter a cell.
9360	DNA polymerase III complex	C	The DNA polymerase III holoenzyme is a complex that contains 10 different types of subunits. These subunits are organized into 3 functionally essential sub-assemblies: the pol III core, the beta sliding clamp processivity factor and the clamp-loading complex. The pol III core carries out the polymerase and the 3'-5' exonuclease proofreading activities. The polymerase is tethered to the template via the sliding clamp processivity factor. The clamp-loading complex assembles the beta processivity factor onto the primer template and plays a central role in the organization and communication at the replication fork.
9361	succinate-CoA ligase complex (ADP-forming)	C	A heterodimeric enzyme complex, composed of an alpha and beta chain, most usually found in (but not limited to) bacteria. Functions in the TCA cycle, hydrolyzing succinyl-CoA into succinate and CoA, thereby forming ATP.
9365	protein histidine kinase complex	C	A complex that possesses protein histidine kinase activity.
9366	enterobactin synthetase complex	C	A multienzyme complex usually composed of four proteins, EntB, EntD, EntE and EntF. Plays a role in the enterobactin biosynthesis pathway.
9368	endopeptidase Clp complex	C	A protein complex comprised of members of the ClpX, ClpC, ClpD, ClpP or ClpR protein families. ClpPs are the proteolytic subunit of active complexes, and ClpA and ClpX form the regulatory subunits. Enzymatically active and inactive complexes can form.
9371	positive regulation of transcription by pheromones	P	Any process involving pheromones that activates or increases the rate of transcription.
9372	quorum sensing	P	The process in which single-celled organisms monitor their population density by detecting the concentration of small, diffusible signal molecules produced by the cells themselves.
9373	regulation of transcription by pheromones	P	Any process involving pheromones that modulates the frequency, rate or extent of transcription.
9374	biotin binding	F	Interacting selectively and non-covalently with biotin (cis-tetrahydro-2-oxothieno(3,4-d)imidazoline-4-valeric acid), the (+) enantiomer of which is very widely distributed in cells and serves as a carrier in a number of enzymatic beta-carboxylation reactions.
9375	ferredoxin hydrogenase complex	C	An enzyme complex that catalyzes the oxidation of reduced ferredoxin. Hydrogenase contains iron-sulfur clusters, and some contain nickel; it can use molecular hydrogen for the reduction of a variety of substances.
9376	HslUV protease complex	C	A protein complex that possesses ATP-dependent protease activity; consists of an ATPase large subunit with homology to other ClpX family ATPases and a peptidase small subunit related to the proteasomal beta-subunits of eukaryotes. In the E. coli complex, a double ring-shaped homohexamer of HslV is capped on each side by a ring-shaped HslU homohexamer.
9378	four-way junction helicase activity	F	Catalysis of the unwinding of the DNA helix of DNA containing four-way junctions, including Holliday junctions.
9379	Holliday junction helicase complex	C	A DNA helicase complex that forms part of a Holliday junction resolvase complex, where the helicase activity is involved in the migration of the junction branch point. The best-characterized example is the E. coli RuvAB complex, in which a hexamer of RuvB subunits possesses helicase activity that is modulated by association with RuvA.
9380	excinuclease repair complex	C	Any of the protein complexes formed by the UvrABC excinuclease system, which carries out nucleotide excision repair. Three different complexes are formed by the 3 proteins as they proceed through the excision repair process. First a complex consisting of two A subunits and two B subunits bind DNA and unwind it around the damaged site. Then, the A subunits disassociate leaving behind a stable complex between B subunits and DNA. Now, subunit C binds to this B+DNA complex and causes subunit B to nick the DNA on one side of the complex while subunit C nicks the DNA on the other side of the complex. DNA polymerase I and DNA ligase can then repair the resulting gap.
9381	excinuclease ABC activity	F	Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acid at sites flanking regions of damaged DNA to which the Uvr ABC excinuclease complexes bind.
9382	imidazoleglycerol-phosphate synthase complex	C	Complex that possesses imidazoleglycerol-phosphate synthase activity.
9383	rRNA (cytosine-C5-)-methyltransferase activity	F	Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to cytosine to form 5-methylcytosine in small subunit ribosomal RNA.
9384	N-acylmannosamine kinase activity	F	Catalysis of the reaction: ATP + N-acyl-D-mannosamine = ADP + N-acyl-D-mannosamine 6-phosphate.
9385	N-acylmannosamine-6-phosphate 2-epimerase activity	F	Catalysis of the reaction: N-acetyl-D-mannosamine-6-phosphate = N-acetyl-D-glucosamine-6-phosphate.
9386	translational attenuation	P	Translational attenuation is a regulatory mechanism analogous to ribosome-mediated transcriptional attenuation. The system requires the presence of a short ORF, called a leader peptide, encoded in the mRNA upstream of the ribosome-binding site and start codon of the gene whose translation is to be regulated. Certain conditions, such as presence of the antibiotic tetracycline in bacteria or amino acid starvation, may cause slowing or stalling of the ribosome translating the leader peptide. The stalled ribosome masks a region of the mRNA and affects which of two alternative mRNA folded structures will form, therefore controlling whether or not a ribosome will bind and initiate translation of the downstream gene. Translational attenuation is analogous to ribosome-mediated transcriptional attenuation, in which mRNA remodeling caused by ribosome stalling regulates transcriptional termination rather than translational initiation.
9389	dimethyl sulfoxide reductase activity	F	Catalysis of the reaction: dimethyl sulfoxide + H+ = dimethyl sulfide + H2O.
9390	dimethyl sulfoxide reductase complex	C	An enzyme complex that catalyzes the formation of dimethyl sulfide from dimethyl sulfoxide.
9392	N-acetyl-anhydromuramoyl-L-alanine amidase activity	F	Catalysis of the reaction: GlcNAc-1,6-anhMurNAc-L-Ala-gamma-D-Glu-DAP-D-Ala + H2O glcNAc-1,6-anhMurNAc + L-Ala-gamma-D-Glu-DAP-D-Ala.
9394	2'-deoxyribonucleotide metabolic process	P	The chemical reactions and pathways involving a 2'-deoxyribonucleotide, a compound consisting of 2'-deoxyribonucleoside (a base linked to a 2'-deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.
9395	phospholipid catabolic process	P	The chemical reactions and pathways resulting in the breakdown of phospholipids, any lipid containing phosphoric acid as a mono- or diester.
9396	folic acid-containing compound biosynthetic process	P	The chemical reactions and pathways resulting in the formation of folic acid and its derivatives.
9397	folic acid-containing compound catabolic process	P	The chemical reactions and pathways resulting in the breakdown of folic acid and its derivatives.
9398	FMN biosynthetic process	P	The chemical reactions and pathways resulting in the formation of FMN, the oxidized form of flavin mononucleotide (riboflavin 5'-(dihydrogen phosphate)), which acts as a coenzyme for a number of oxidative enzymes including NADH dehydrogenase.
9399	nitrogen fixation	P	The process in which nitrogen is taken from its relatively inert molecular form (N2) in the atmosphere and converted into nitrogen compounds useful for other chemical processes, such as ammonia, nitrate and nitrogen dioxide.
9400	signal transducer, downstream of receptor, with serine/threonine phosphatase activity	F	Conveys a signal from an upstream receptor or intracellular signal transducer by catalysis of the reaction: protein serine phosphate + H2O = protein serine + phosphate, and protein threonine phosphate + H2O = protein threonine + phosphate.
9401	phosphoenolpyruvate-dependent sugar phosphotransferase system	P	The uptake and phosphorylation of specific carbohydrates from the extracellular environment; uptake and phosphorylation are coupled, making the PTS a link between the uptake and metabolism of sugars; phosphoenolpyruvate is the original phosphate donor; phosphoenolpyruvate passes the phosphate via a signal transduction pathway, to enzyme 1 (E1), which in turn passes it on to the histidine protein, HPr; the next step in the system involves sugar-specific membrane-bound complex, enzyme 2 (EII), which transports the sugar into the cell; it includes the sugar permease, which catalyzes the transport reactions; EII is usually divided into three different domains, EIIA, EIIB, and EIIC.
9403	toxin biosynthetic process	P	The chemical reactions and pathways resulting in the formation of toxin, a poisonous compound (typically a protein) that is produced by cells or organisms and that can cause disease when introduced into the body or tissues of an organism.
9404	toxin metabolic process	P	The chemical reactions and pathways involving a toxin, a poisonous compound (typically a protein) that is produced by cells or organisms and that can cause disease when introduced into the body or tissues of an organism.
9405	pathogenesis	P	The set of specific processes that generate the ability of an organism to induce an abnormal, generally detrimental state in another organism.
9407	toxin catabolic process	P	The chemical reactions and pathways resulting in the breakdown of toxin, a poisonous compound (typically a protein) that is produced by cells or organisms and that can cause disease when introduced into the body or tissues of an organism.
9408	response to heat	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.
9409	response to cold	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cold stimulus, a temperature stimulus below the optimal temperature for that organism.
9410	response to xenobiotic stimulus	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a xenobiotic compound stimulus. Xenobiotic compounds are compounds foreign to living organisms.
9411	response to UV	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ultraviolet radiation (UV light) stimulus. Ultraviolet radiation is electromagnetic radiation with a wavelength in the range of 10 to 380 nanometers.
9413	response to flooding	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating flooding, short-term immersion in water.
9414	response to water deprivation	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a water deprivation stimulus, prolonged deprivation of water.
9415	response to water	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of water.
9416	response to light stimulus	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a light stimulus, electromagnetic radiation of wavelengths classified as infrared, visible or ultraviolet light.
9418	pilus shaft	C	The long, slender, mid section of a pilus.
9419	pilus tip	C	The pointed extremity furthest from the cell of a pilus.
9420	bacterial-type flagellum filament	C	The long (approximately 20 nm), thin external structure of the flagellum, which acts as a propeller. Examples of this component are found in bacteria.
9421	bacterial-type flagellum filament cap	C	The proteinaceous structure at the distal tip of the flagellar filament. Examples of this component are found in bacteria.
9422	bacterial-type flagellum hook-filament junction	C	The region of the flagellum where the hook and filament meet. Examples of this component are found in bacteria.
9423	chorismate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of the unsymmetrical ether derived from phosphoenolpyruvate and 5-phosphoshikimic acid formed as an intermediate in the biosynthesis of aromatic amino acids and many other compounds.
9424	bacterial-type flagellum hook	C	The portion of the flagellum that connects the filament to the basal body. Examples of this component are found in bacteria.
9425	bacterial-type flagellum basal body	C	One of the three major substructures of the flagellin-based flagellum; a structure consisting of a rod, a series of rings, the Mot proteins, the switch complex and the flagellum-specific export apparatus. The rings anchor the flagellum to the cytoplasmic membrane (MS ring), the peptidoglycan (P ring) and the outer membrane (L ring). Examples of this component are found in bacteria.
9426	bacterial-type flagellum basal body, distal rod	C	The portion of the central rod of the flagellar basal body that is distal to the cell membrane; spans most of the distance between the inner and outer membranes. Examples of this component are found in bacteria.
9427	bacterial-type flagellum basal body, distal rod, L ring	C	One of the rings of the flagellar basal body; anchors the basal body to the outer membrane. Examples of this component are found in bacteria.
9428	bacterial-type flagellum basal body, distal rod, P ring	C	One of the rings of the flagellar basal body; anchors the basal body to the peptidoglycan layer. Examples of this component are found in bacteria.
9429	bacterial-type flagellum basal body, proximal rod	C	The portion of the central rod of the flagellar basal body that is proximal to the cell membrane; proximal rod connects the distal rod to the flagellar motor. Examples of this component are found in bacteria.
9431	bacterial-type flagellum basal body, MS ring	C	One of the rings of the flagellar basal body; a double-flanged ring that anchors the basal body to the cytoplasmic membrane. Examples of this component are found in bacteria.
9432	SOS response	P	An error-prone process for repairing damaged microbial DNA.
9433	bacterial-type flagellum basal body, C ring	C	Cytoplasmic ring located at the base of the flagellar basal body; acts as a rotor; includes three switch proteins, which generate torque and can change their conformational state in a bimodal fashion, so that the motor direction can switch between clockwise and counterclockwise. Examples of this component are found in bacteria.
9435	NAD biosynthetic process	P	The chemical reactions and pathways resulting in the formation of nicotinamide adenine dinucleotide, a coenzyme present in most living cells and derived from the B vitamin nicotinic acid; biosynthesis may be of either the oxidized form, NAD, or the reduced form, NADH.
9436	glyoxylate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of glyoxylate, the anion of glyoxylic acid, HOC-COOH.
9437	carnitine metabolic process	P	The chemical reactions and pathways involving carnitine (hydroxy-trimethyl aminobutyric acid), a compound that participates in the transfer of acyl groups across the inner mitochondrial membrane.
9438	methylglyoxal metabolic process	P	The chemical reactions and pathways involving methylglyoxal, CH3-CO-CHO, the aldehyde of pyruvic acid.
9439	cyanate metabolic process	P	The chemical reactions and pathways involving cyanate, NCO-, the anion of cyanic acid.
9440	cyanate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of cyanate, NCO-, the anion of cyanic acid.
9441	glycolate metabolic process	P	The chemical reactions and pathways involving glycolate, the anion of hydroxyethanoic acid (glycolic acid).
9442	allantoin assimilation pathway	P	The pathways by which allantoin is processed and converted to ureidoglycolate, and then into metabolically useful substrates. E. coli are able to utilize allantoin as a sole nitrogen source under anaerobic conditions by converting it to ureidoglycolate; this may be further metabolized to produce glyoxylate and thence 3-phosphoglycerate, or alternatively oxidized to oxolureate, which can converted into oxamate and carbamoylphosphate. This may then be further metabolized to CO2, NH4+ and ATP.
9443	pyridoxal 5'-phosphate salvage	P	Any process that generates pyridoxal 5'-phosphate, the active form of vitamin B6, from derivatives of it without de novo synthesis.
9444	pyruvate oxidation	P	The chemical reactions and pathways resulting in the conversion of pyruvate to acetylphosphate.
9445	putrescine metabolic process	P	The chemical reactions and pathways involving putrescine, 1,4-diaminobutane; putrescine can be formed by decarboxylation of ornithine and is the metabolic precursor of spermidine and spermine.
9446	putrescine biosynthetic process	P	The chemical reactions and pathways resulting in the formation of putrescine, 1,4-diaminobutane; putrescine can be synthesized from arginine or ornithine and is the metabolic precursor of spermidine and spermine.
9447	putrescine catabolic process	P	The chemical reactions and pathways resulting in the breakdown of putrescine, 1,4-diaminobutane; putrescine is the metabolic precursor of spermidine and spermine.
9448	gamma-aminobutyric acid metabolic process	P	The chemical reactions and pathways involving gamma-aminobutyric acid (GABA, 4-aminobutyrate), an amino acid which acts as a neurotransmitter in some organisms.
9449	gamma-aminobutyric acid biosynthetic process	P	The chemical reactions and pathways resulting in the formation of gamma-aminobutyric acid (GABA, 4-aminobutyrate), an amino acid which acts as a neurotransmitter in some organisms.
9450	gamma-aminobutyric acid catabolic process	P	The chemical reactions and pathways resulting in the breakdown of gamma-aminobutyric acid (GABA, 4-aminobutyrate), an amino acid which acts as a neurotransmitter in some organisms.
9451	RNA modification	P	The covalent alteration of one or more nucleotides within an RNA molecule to produce an RNA molecule with a sequence that differs from that coded genetically.
9452	7-methylguanosine RNA capping	P	The sequence of enzymatic reactions by which the 5' cap structure, an inverted 7-methylguanosine linked via a 5'-5' triphosphate bridge (m7G(5')ppp(5')X) to the first transcribed residue, is added to a nascent transcript.
9453	energy taxis	P	The directed movement of a motile cell or organism in response to physical parameters involved in energy generation, such as light, oxygen, and oxidizable substrates.
9454	aerotaxis	P	The directed movement of a motile cell or organism in response to environmental oxygen.
9455	redox taxis	P	The directed movement of a motile cell or organism in response to redox potential.
9486	cytochrome bo3 ubiquinol oxidase activity	F	Catalysis of the reaction: 2 ubiquinol + O2 + 4 H+ = 2 ubiquinone + 2 H2O + 4 H+ [periplasmic space].
9496	plastoquinol--plastocyanin reductase activity	F	Catalysis of the reaction: 2 H(+)[side 1] + 2 oxidized plastocyanin + plastoquinol-1 = 2 H(+)[side 2] + 2 reduced plastocyanin + plastoquinone. This reaction involves the concomitant transfer of 2 H+ ions across a membrane.
9501	amyloplast	C	A plastid whose main function is to synthesize and store starch.
9503	thylakoid light-harvesting complex	C	A thylakoid membrane complex of chlorophylls a and b together with chlorophyll a-b binding proteins. In addition, LHCs contain a number of other proteins, the function of which is speculative, together with accessory pigments. The LHCs capture and transfer energy to photosystems I and II. An example of this is found in Arabidopsis thaliana.
9504	cell plate	C	The nascent cell membrane and cell wall structure that forms between two daughter nuclei near the center of a dividing plant cell. It develops at the equitorial region of the phragmoplast. It grows outwards to join with the lateral walls and form two daughter cells.
9505	plant-type cell wall	C	A more or less rigid stucture lying outside the cell membrane of a cell and composed of cellulose and pectin and other organic and inorganic substances.
9506	plasmodesma	C	A fine cytoplasmic channel, found in all higher plants, that connects the cytoplasm of one cell to that of an adjacent cell.
9507	chloroplast	C	A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma.
9508	plastid chromosome	C	A circular DNA molecule containing plastid encoded genes.
9509	chromoplast	C	A plastid containing pigments other than chlorophyll, usually yellow and orange carotenoid pigments.
9510	plasmodesmatal desmotubule	C	A tightly wound cylinder of membrane that is located within the plasmodesmal pore and runs the length of the plasmodesma. The desmotubule likely provides a rigid stability to plasmodesmata and confers a fixed diameter and pore size to the plasmodesmal canal, and is linked to the endoplasmic reticulum in each of the adjacent cell.
9511	plasmodesmatal endoplasmic reticulum	C	Endoplasmic reticulum found in plasmodesmata, junctions connecting the cytoplasm of adjacent plant cells.
9512	cytochrome b6f complex	C	Complex that transfers electrons from reduced plastoquinone to oxidized plastocyanin and translocates protons from the stroma to the lumen. The complex contains a core structure of three catalytic subunits: cytochrome b, the Rieske iron sulfur protein (ISP), and cytochrome f, which are arranged in an integral membrane-bound dimeric complex; additional subunits are present, and vary among different species.
9513	etioplast	C	A plastid arrested in the development of chloroplasts from proplastids due to absence of light or low light conditions.
9514	glyoxysome	C	A specialized form of peroxisome that contains the enzymes of the glyoxylate pathway. The glyoxysome is found in some plant cells, notably the cells of germinating seeds.
9515	granal stacked thylakoid	C	Appressed thylakoid membranes that are part of a granum (stacked regions). A characteristic of these appressed regions is the preferential localization of photosystem II.
9516	leucoplast	C	A colorless plastid involved in the synthesis of monoterpenes.
9517	PSII associated light-harvesting complex II	C	Protein-pigment complex associated with photosystem II.
9518	PSI associated light-harvesting complex I	C	Protein-pigment complex associated with photosystem I.
9519	middle lamella	C	Layer of intercellular material, chiefly pectic substances, cementing together the primary walls of contiguous cells.
9521	photosystem	C	A complex located in a photosynthetic membrane that consists of a photoreaction center associated with accessory pigments and electron carriers. Examples of this component are found in Arabidopsis thaliana and in photosynthetic bacterial and archaeal species.
9522	photosystem I	C	A photosystem that contains an iron-sulfur reaction center associated with accessory pigments and electron carriers. In cyanobacteria and chloroplasts, photosystem I functions as a light-dependent plastocyanin-ferredoxin oxidoreductase, transferring electrons from plastocyanin to ferredoxin; in photosynthetic bacteria that have only a single type I photosystem, such as the green sulfur bacteria, electrons can go either to ferredoxin (Fd) -> NAD+ or to menaquinone (MK) -> Cytb/FeS -> Cytc555 -> photosystem I (cyclic photophosphorylation).
9523	photosystem II	C	A photosystem that contains a pheophytin-quinone reaction center with associated accessory pigments and electron carriers. In cyanobacteria and chloroplasts, in the presence of light, PSII functions as a water-plastoquinone oxidoreductase, transferring electrons from water to plastoquinone, whereas other photosynthetic bacteria carry out anoxygenic photosynthesis and oxidize other compounds to re-reduce the photoreaction center.
9524	phragmoplast	C	Fibrous structure (light microscope view) that arises between the daughter nuclei at telophase and within which the initial partition (cell plate), dividing the mother cell in two (cytokinesis), is formed. Appears at first as a spindle connected to the two nuclei, but later spreads laterally in the form of a ring. Consists of microtubules.
9525	phragmosome	C	A flattened membranous vesicle containing cell wall components.
9526	plastid envelope	C	The double lipid bilayer enclosing a plastid and separating its contents from the rest of the cytoplasm; includes the intermembrane space.
9527	plastid outer membrane	C	The outer, i.e. cytoplasm-facing, lipid bilayer of the plastid envelope.
9528	plastid inner membrane	C	The inner, i.e. lumen-facing, lipid bilayer of the plastid envelope; also faces the plastid stroma.
9529	plastid intermembrane space	C	The region between the inner and outer lipid bilayers of the plastid envelope.
9530	primary cell wall	C	A plant cell wall that is still able to expand, permitting cell growth. Primary cell walls contain more pectin than secondary walls and no lignin is present.
9531	secondary cell wall	C	A plant cell wall that is no longer able to expand and so does not permit growth. Secondary cell walls contain less pectin that primary cell walls. The secondary cell is mostly composed of cellulose and is strengthened with lignin.
9532	plastid stroma	C	The proteinaceous ground substance of plastids.
9533	chloroplast stromal thylakoid	C	Unstacked thylakoids that connect the grana stacks through the stroma.
9534	chloroplast thylakoid	C	Sac-like membranous structures (cisternae) in a chloroplast combined into stacks (grana) and present singly in the stroma (stroma thylakoids or frets) as interconnections between grana. An example of this component is found in Arabidopsis thaliana.
9535	chloroplast thylakoid membrane	C	The pigmented membrane of a chloroplast thylakoid. An example of this component is found in Arabidopsis thaliana.
9536	plastid	C	Any member of a family of organelles found in the cytoplasm of plants and some protists, which are membrane-bounded and contain DNA. Plant plastids develop from a common type, the proplastid.
9537	proplastid	C	The precursor of other plastids.
9538	photosystem I reaction center	C	A photochemical system containing P700, the chlorophyll a dimer that functions as a primary electron donor. Functioning as a light-dependent plastocyanin-ferredoxin oxidoreductase, it transfers electrons from plastocyanin to ferredoxin.
9539	photosystem II reaction center	C	An integral membrane complex containing P680, the chlorophyll a molecule that functions as a primary electron donor. In the light, functioning as a water-plastoquinone oxidoreductase, it transfers electrons from water to plastoquinone.
9540	zeaxanthin epoxidase [overall] activity	F	Catalysis of the reactions: zeaxanthin + NAD(P)H + H+ + O2 = antheraxanthin + NAD(P)+ + H2O; and antheraxanthin + NAD(P)H + H+ + O2 = violaxanthin + NAD(P)+ + H2O.
9541	etioplast prolamellar body	C	A three dimensional regular lattice found in etioplasts. It is composed of a continuous system of tubules but when exposed to light the symmetrical arrangement is rapidly lost as tubules become pinched off into two dimensional sections of lattice. These for perforated sheets of membrane that move apart, extend and increase, finally establishing the typical granal and intergranal lamellae of the mature chloroplast.
9542	granum	C	Distinct stack of lamellae seen within chloroplasts. Grana contain the pigments, electron transfer compounds, and enzymes essential to the light-dependent reactions of photosynthesis.
9543	chloroplast thylakoid lumen	C	The cavity enclosed within the chloroplast thylakoid membrane. An example of this component is found in Arabidopsis thaliana.
9544	chloroplast ATP synthase complex	C	The protein complex that catalyzes the phosphorylation of ADP to ATP in chloroplasts.
9545	elaioplast	C	A leucoplast in which oil is stored.
9546	plasmodesmatal cytoplasmic sleeve	C	The space between the plasma membrane and the desmotubule of a plasmodesma.
9547	plastid ribosome	C	A ribosome contained within a plastid.
9548	plasmodesmatal plasma membrane	C	The portion of the plasma membrane surrounding a plasmodesma.
9549	cellulose microfibril	C	A microfibril composed of cellulose arranged in orthogonal layers. Cellulose is a straight chain polysaccharide composed of B(14) linked glucose subunits. It is a major component of plant cell walls. Higher plant microfibrils are about 10nm in diameter and extremely long in relation to their width. The cellulose molecules are oriented parallel to the long axis of the microfibril in a paracrystalline array, which provides great tensile strength. The microfibrils are held in place by the wall matrix and their orientation is closely controlled by the cell.
9550	primary plasmodesma	C	A plasmodesma that consists of a simple, single channel; found predominantly in young tissue and formed as a function of cell plate formation during cytokinesis.
9551	secondary plasmodesma	C	A plasmodesma with a branched structure, often with many channels leading into a larger central cavity; found in older tissues and usually derived from preexisting primary plasmodesmata.
9553	embryo sac development	P	The process whose specific outcome is the progression of the embryo sac over time, from its formation to the mature structure. The process begins with the meiosis of the megasporocyte to form four haploid megaspores. Three of the megaspores disintegrate, and the fourth undergoes mitosis giving rise to a binucleate syncytial embryo sac. The two haploid nuclei migrate to the opposite poles of the embryo sac and then undergo two rounds of mitosis generating four haploid nuclei at each pole. One nucleus from each set of four migrates to the center of the cell. Cellularization occurs, resulting in an eight-nucleate seven-celled structure. This structure contains two synergid cells and an egg cell at the micropylar end, and three antipodal cells at the other end. A binucleate endosperm mother cell is formed at the center. The two polar nuclei fuse resulting in a mononucleate diploid endosperm mother cell. The three antipodal cells degenerate.
9554	megasporogenesis	P	The process in which the megasporocyte undergoes meiosis, giving rise to four haploid megaspores in the nucellus.
9555	pollen development	P	The process whose specific outcome is the progression of the pollen grain over time, from its formation to the mature structure. The process begins with the meiosis of the microsporocyte to form four haploid microspores. The nucleus of each microspore then divides by mitosis to form a two-celled organism, the pollen grain, that contains a tube cell as well as a smaller generative cell. The pollen grain is surrounded by an elaborate cell wall. In some species, the generative cell immediately divides again to give a pair of sperm cells. In most flowering plants, however this division takes place later, in the tube that develops when a pollen grain germinates.
9556	microsporogenesis	P	The process in which the microsporocyte undergoes meiosis, giving rise to four haploid microspores.
9557	antipodal cell differentiation	P	The process in which an uncellularized nucleus cellularizes and acquires the specialized features of an antipodal cell.
9558	embryo sac cellularization	P	The process in which the eight-nucleate single celled female gametophyte develops into the seven-celled female gametophyte. This mature structure contains two synergid cells and an egg cell at the micropylar end, and three antipodal cells at the other end. A binucleate endosperm mother cell is formed at the center. An example of this process is found in Arabidopsis thaliana.
9559	embryo sac central cell differentiation	P	The process in which the two uncellularized polar nuclei cellularize, fuse and acquire the specialized features of a mononucleate diploid central cell.
9560	embryo sac egg cell differentiation	P	The process in which an uncellularized embryo sac nucleus cellularizes and acquires the specialized features of an egg cell. An example of this process is found in Arabidopsis thaliana.
9561	megagametogenesis	P	The process whose specific outcome is the progression of the embryo sac over time, from its formation as the megaspore to the mature structure. The process begins when three of the four haploid megaspores disintegrate, and the fourth undergoes mitosis giving rise to a binucleate syncytial embryo sac. The two haploid nuclei migrate to the opposite poles of the embryo sac and then undergo two rounds of mitosis generating four haploid nuclei at each pole. One nucleus from each set of four migrates to the center of the cell. Cellularization occurs, resulting in an eight-nucleate seven-celled structure. This structure contains two synergid cells and an egg cell at the micropylar end, and three antipodal cells at the other end. A binucleate endosperm mother cell is formed at the center.
9562	embryo sac nuclear migration	P	The directed movement of an embryo sac nucleus to the pole or center of the cell.
9563	synergid differentiation	P	The process in which an uncellularized nucleus cellularizes and acquires the specialized features of a synergid cell.
9566	fertilization	P	The union of gametes of opposite sexes during the process of sexual reproduction to form a zygote. It involves the fusion of the gametic nuclei (karyogamy) and cytoplasm (plasmogamy).
9567	double fertilization forming a zygote and endosperm	P	Fertilization where one of the two sperm nuclei from the pollen tube fuses with the egg nucleus to form a 2n zygote, and the other fuses with the two polar nuclei to form the 3n primary endosperm nucleus and then develops into the endosperm. The ploidy level of the 2n zygote and 3n primary endosperm nucleus is determined by the ploidy level of the parents involved. An example of this component is found in Arabidopsis thaliana.
9568	amyloplast starch grain	C	Plant storage body for amylose and amylopectin, 1-100um in diameter, and located in amyloplasts. Also contains small amounts of enzymes, amino acids, lipids and nucleic acids. The shape of the grain varies widely amongst species, but is often spherical or disk-shaped.
9569	chloroplast starch grain	C	Plant storage body for amylose and amylopectin, 1-100um in diameter, and located in chloroplasts. Also contains small amounts of enzymes, amino acids, lipids and nucleic acids. The shape of the grain varies widely amongst species, but is often spherical or disk-shaped.
9570	chloroplast stroma	C	The space enclosed by the double membrane of a chloroplast but excluding the thylakoid space. It contains DNA, ribosomes and some temporary products of photosynthesis.
9571	proplastid stroma	C	The space enclosed by the double membrane of a proplastid.
9573	chloroplast ribulose bisphosphate carboxylase complex	C	A complex, located in the chloroplast, containing either both large and small subunits or just small subunits which carries out the activity of producing 3-phosphoglycerate from carbon dioxide and ribulose-1,5-bisphosphate. An example of this component is found in Arabidopsis thaliana.
9574	preprophase band	C	A dense band of microtubules, 1-3 pm wide, that appears just beneath the cell membrane before the start of cell division in the cells of higher plants. It precedes the onset of prophase and then disappears as mitosis begins, yet it somehow determines the plane of orientation of the new cell plate forming in late telophase and marks the zone of the parental cell wall where fusion with the growing cell plate ultimately occurs.
9575	chromoplast stroma	C	The space enclosed by the double membrane of a chromoplast but excluding the photosynthetic material.
9576	leucoplast stroma	C	The space enclosed by the double membrane of a leucoplast.
9577	elaioplast stroma	C	The space enclosed by the double membrane of an elaioplast.
9578	etioplast stroma	C	The space enclosed by the double membrane of an etioplast but excluding the prothylakoid space. It contains the etioplast DNA.
9579	thylakoid	C	A membranous cellular structure that bears the photosynthetic pigments in plants, algae, and cyanobacteria. In cyanobacteria thylakoids are of various shapes and are attached to, or continuous with, the plasma membrane. In eukaryotes they are flattened, membrane-bounded disk-like structures located in the chloroplasts; in the chloroplasts of higher plants the thylakoids form dense stacks called grana. Isolated thylakoid preparations can carry out photosynthetic electron transport and the associated phosphorylation.
9581	detection of external stimulus	P	The series of events in which an external stimulus is received by a cell and converted into a molecular signal.
9582	detection of abiotic stimulus	P	The series of events in which an (non-living) abiotic stimulus is received by a cell and converted into a molecular signal.
9583	detection of light stimulus	P	The series of events in which a light stimulus (in the form of photons) is received and converted into a molecular signal.
9584	detection of visible light	P	The series of events in which a visible light stimulus is received by a cell and converted into a molecular signal. A visible light stimulus is electromagnetic radiation that can be perceived visually by an organism; for organisms lacking a visual system, this can be defined as light with a wavelength within the range 380 to 780 nm.
9585	red, far-red light phototransduction	P	The sequence of reactions within a cell required to convert absorbed photons from red or far-red light into a molecular signal; the red, far-red light range is defined as having a wavelength within the range 660-730 nm.
9588	UV-A, blue light phototransduction	P	The sequence of reactions within a cell required to convert absorbed photons from UV-A or blue light into a molecular signal; the UV-A, blue light range is defined as having a wavelength within the range of 315 to 400 nm.
9589	detection of UV	P	The series of events in which an ultraviolet radiation (UV light) stimulus is received and converted into a molecular signal. Ultraviolet radiation is electromagnetic radiation with a wavelength in the range of 10 to 380 nanometers.
9590	detection of gravity	P	The series of events in which a gravitational stimulus is received and converted into a molecular signal.
9593	detection of chemical stimulus	P	The series of events in which a chemical stimulus is received by a cell and converted into a molecular signal.
9594	detection of nutrient	P	The series of events in which a nutrient stimulus is received by a cell and converted into a molecular signal.
9595	detection of biotic stimulus	P	The series of events in which a biotic stimulus, one caused or produced by a living organism, is received and converted into a molecular signal.
9597	detection of virus	P	The series of events in which a stimulus from a virus is received and converted into a molecular signal.
9600	detection of nematode	P	The series of events in which a stimulus from a nematode is received and converted into a molecular signal.
9601	detection of insect	P	The series of events in which a stimulus from an insect is received and converted into a molecular signal.
9602	detection of symbiont	P	The series of events in which a stimulus from a symbiont (an organism living in close physical association with an organism of a different species) is received and converted into a molecular signal. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.
9603	detection of symbiotic fungus	P	The series of events in which a stimulus from a symbiotic fungus, a fungus living in close physical association with another organism, is received and converted into a molecular signal.
9604	detection of symbiotic bacterium	P	The series of events in which a stimulus from a symbiotic bacterium, a bacterium living in close physical association with another organism, is received and converted into a molecular signal.
9605	response to external stimulus	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an external stimulus.
9606	tropism	P	The movement of an organism, or part of an organism, in response to an external source of stimulus, usually toward or away from it.
9607	response to biotic stimulus	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a biotic stimulus, a stimulus caused or produced by a living organism.
9608	response to symbiont	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a symbiont, an organism living with an organism of a different species in close physical association. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.
9609	response to symbiotic bacterium	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a symbiotic bacterium, a bacterium living in close physical association with another organism.
9610	response to symbiotic fungus	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a symbiotic fungus, a fungus living in close physical association with another organism.
9611	response to wounding	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to the organism.
9612	response to mechanical stimulus	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mechanical stimulus.
9615	response to virus	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a virus.
9616	virus induced gene silencing	P	Specific posttranscriptional gene inactivation ('silencing') both of viral gene(s), and host gene(s) homologous to the viral genes. This silencing is triggered by viral infection, and occurs through a specific decrease in the level of mRNA of both host and viral genes.
9617	response to bacterium	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a bacterium.
9620	response to fungus	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a fungus.
9623	response to parasitic fungus	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a parasitic fungus, a fungus which spends all or part of its life in or on another organism from which it obtains nourishment and/or protection.
9624	response to nematode	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a nematode.
9625	response to insect	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from an insect.
9626	plant-type hypersensitive response	P	The rapid, localized death of plant cells in response to invasion by a pathogen.
9627	systemic acquired resistance	P	The salicylic acid mediated response to a pathogen which confers broad spectrum resistance.
9628	response to abiotic stimulus	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abiotic (non-living) stimulus.
9629	response to gravity	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gravitational stimulus.
9630	gravitropism	P	The orientation of plant parts under the stimulation of gravity.
9631	cold acclimation	P	Any process that increases freezing tolerance of an organism in response to low, nonfreezing temperatures.
9635	response to herbicide	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a herbicide stimulus. Herbicides are chemicals used to kill or control the growth of plants.
9636	response to toxic substance	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a toxic stimulus.
9637	response to blue light	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a blue light stimulus. Blue light is electromagnetic radiation with a wavelength of between 440 and 500nm.
9638	phototropism	P	The movement of an organism, or part of an organism, in response to a light stimulus, usually toward or away from it.
9639	response to red or far red light	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a red or far red light stimulus. Red light is electromagnetic radiation of wavelength of 580-700nm. Far red light is electromagnetic radiation of wavelength 700-800nm. An example of this response is seen at the beginning of many plant species developmental stages. These include germination, and the point when cotyledon expansion is triggered. In certain species these processes take place in response to absorption of red light by the pigment molecule phytochrome, but the signal can be reversed by exposure to far red light. During the initial phase the phytochrome molecule is only present in the red light absorbing form, but on absorption of red light it changes to a far red light absorbing form, triggering progress through development. An immediate short period of exposure to far red light entirely returns the pigment to its initial state and prevents triggering of the developmental process. A thirty minute break between red and subsequent far red light exposure renders the red light effect irreversible, and development then occurs regardless of whether far red light exposure subsequently occurs.
9640	photomorphogenesis	P	The control of plant growth, development, and differentiation by the duration and nature of light, independent of photosynthesis.
9641	shade avoidance	P	Shade avoidance is a set of responses that plants display when they are subjected to the shade of another plant. It often includes elongation, altered flowering time, increased apical dominance and altered partitioning of resources. Plants are able to distinguish between the shade of an inanimate object (e.g. a rock) and the shade of another plant due to the altered balance between red and far-red light in the shade of a plant; this balance between red and far-red light is perceived by phytochrome.
9642	response to light intensity	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a light intensity stimulus.
9643	photosynthetic acclimation	P	A response to light intensity in which exposure to medium-intensity light results in increased tolerance to high-intensity light.
9644	response to high light intensity	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a high light intensity stimulus.
9645	response to low light intensity stimulus	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a low light intensity stimulus. Low light intensity is defined as a level of electromagnetic radiation at or below 0.1 micromols/m2.
9646	response to absence of light	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an absence of light stimuli.
9647	skotomorphogenesis	P	The control of plant growth, development, and differentiation in response to growth in darkness.
9648	photoperiodism	P	Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a period of light or dark of a given length, measured relative to a particular duration known as the 'critical day length'. The critical day length varies between species.
9649	entrainment of circadian clock	P	The synchronization of a circadian rhythm to environmental time cues such as light.
9650	UV protection	P	Any process in which an organism or cell protects itself from ultraviolet radiation (UV), which may also result in resistance to repeated exposure to UV.
9651	response to salt stress	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment.
9652	thigmotropism	P	The movement of an organism, or part of an organism, such as leaves or tendrils, in response to a touch stimulus, usually toward or away from it.
9653	anatomical structure morphogenesis	P	The process in which anatomical structures are generated and organized. Morphogenesis pertains to the creation of form.
9654	photosystem II oxygen evolving complex	C	A complex, composed of a cluster of manganese, calcium and chloride ions bound to extrinsic proteins, that catalyzes the splitting of water to O2 and 4 H+. In cyanobacteria there are five extrinsic proteins in OEC (PsbO, PsbP-like, PsbQ-like, PsbU and PsbV), while in plants there are only three (PsbO, PsbP and PsbQ).
9655	PSII associated light-harvesting complex II, core complex	C	The pigment-protein complex primarily associated to PSII in higher plants, green algae and cyanobacteria that directly transfers electrons to the reaction center.
9656	PSII associated light-harvesting complex II, peripheral complex	C	Pigment-protein complex primarily associated to PSII in plants, green algae and cyanobacteria. Involved in state transitions that cause migration to PSI under certain environmental conditions such as high light.
9657	plastid organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a plastid.
9658	chloroplast organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the chloroplast.
9659	leucoplast organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a leucoplast. A leucoplast is a colorless plastid involved in the synthesis of monoterpenes.
9660	amyloplast organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an amyloplast. An amyloplast is a plastid whose main function is to synthesize and store starch.
9661	chromoplast organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the chromoplast. A chromoplast is a plastid containing pigments other than chlorophyll, usually yellow and orange carotenoid pigments.
9662	etioplast organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an etioplast. An etioplast is a plastid arrested in the development of chloroplasts from proplastids due to absence of light or low light conditions.
9663	plasmodesma organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a plasmodesma, a fine cytoplasmic channel, found in all higher plants, that connects the cytoplasm of one cell to that of an adjacent cell.
9664	plant-type cell wall organization	P	A process that results in the assembly and arrangement of constituent parts of the cellulose and pectin-containing cell wall, or in the disassembly of the cellulose and pectin-containing cell wall. This process is carried out at the cellular level. An example of this process is found in Arabidopsis thaliana.
9665	plastid inheritance	P	The partitioning of plastids between daughter cells at cell division.
9666	plastid outer membrane organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the outer membrane of a plastid.
9667	plastid inner membrane organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the inner membrane of a plastid.
9668	plastid membrane organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of either of the lipid bilayers surrounding a plastid.
9669	sucrose:monovalent cation symporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sucrose(out) + monovalent cation(out) = sucrose(in) + monovalent cation(in).
9670	triose-phosphate:phosphate antiporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: triose-phosphate(out) + phosphate(in) = triose-phosphate(in) + phosphate(out).
9671	nitrate:proton symporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: nitrate(out) + H+(out) = nitrate(in) + H+(in).
9672	auxin:proton symporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: auxin(out) + H+(out) = auxin(in) + H+(in).
9673	low-affinity phosphate transmembrane transporter activity	F	Enables the transfer of phosphate from one side of the membrane to the other. In low-affinity transport the transporter is able to bind the solute only if it is present at very high concentrations.
9674	potassium:sodium symporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: K+(out) + Na+(out) = K+(in) + Na+(in).
9675	high-affinity sulfate:proton symporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sulfate(out) + H+(out) = sulfate(in) + H+(in). In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.
9676	low-affinity sulfate:proton symporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sulfate(out) + H+(out) = sulfate(in) + H+(in). In low-affinity transport the transporter is able to bind the solute only if it is present at very high concentrations.
9677	double fertilization forming two zygotes	P	Rudimentary double fertilization where one of the two sperm nuclei from the pollen tube fuses with the egg nucleus to form a 2n zygote, and the other fuses with the ventral canal cell nucleus to form a second zygote, which soon degenerates. An example of this process is found in the Gnetophytes, such as Welwitschia mirabilis.
9678	hydrogen-translocating pyrophosphatase activity	F	Catalysis of the hydrolysis of pyrophosphate, which generates a proton motive force.
9679	hexose:proton symporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: hexose(out) + H+(out) = hexose(in) + H+(in).
9682	induced systemic resistance	P	A response to non-pathogenic bacteria that confers broad spectrum systemic resistance to disease that does not depend upon salicylic acid signaling.
9683	indoleacetic acid metabolic process	P	The chemical reactions and pathways involving indole-3-acetic acid, a compound which functions as a growth regulator in plants.
9684	indoleacetic acid biosynthetic process	P	The chemical reactions and pathways resulting in the formation of indole-3-acetic acid, a compound which functions as a growth regulator in plants.
9685	gibberellin metabolic process	P	The chemical reactions and pathways involving gibberellin. Gibberellins are a class of highly modified terpenes that function as plant growth regulators.
9686	gibberellin biosynthetic process	P	The chemical reactions and pathways resulting in the formation of gibberellin. Gibberellins are a class of highly modified terpenes that function as plant growth regulators.
9687	abscisic acid metabolic process	P	The chemical reactions and pathways involving abscisic acid, 5-(1-hydroxy-2,6,6,trimethyl-4-oxocyclohex-2-en-1-y1)-3-methylpenta-2,4-dienoic acid.
9688	abscisic acid biosynthetic process	P	The chemical reactions and pathways resulting in the formation of abscisic acid, 5-(1-hydroxy-2,6,6,trimethyl-4-oxocyclohex-2-en-1-y1)-3-methylpenta-2,4-dienoic acid.
9689	induction of phytoalexin biosynthetic process	P	The activation of the chemical reactions and pathways resulting in the formation of phytoalexins, low-molecular mass, lipophilic antimicrobial compounds that accumulate rapidly at sites of incompatible pathogen infection.
9690	cytokinin metabolic process	P	The chemical reactions and pathways involving cytokinins, a class of adenine-derived compounds that can function in plants as growth regulators.
9691	cytokinin biosynthetic process	P	The chemical reactions and pathways resulting in the formation of cytokinins, a class of adenine-derived compounds that can function in plants as growth regulators.
9692	ethylene metabolic process	P	The chemical reactions and pathways involving ethylene (C2-H4, ethene), a simple hydrocarbon gas that can function in plants as a growth regulator.
9693	ethylene biosynthetic process	P	The chemical reactions and pathways resulting in the formation of ethylene (C2-H4, ethene), a simple hydrocarbon gas that can function in plants as a growth regulator.
9694	jasmonic acid metabolic process	P	The chemical reactions and pathways involving jasmonic acid, a fatty acid derivative with the formula (1R-(1 alpha, 2 beta(Z)))-3-oxo-2-(2-pentenyl)cyclopentaneacetic acid.
9695	jasmonic acid biosynthetic process	P	The chemical reactions and pathways resulting in the formation of jasmonic acid, a fatty acid derivative.
9696	salicylic acid metabolic process	P	The chemical reactions and pathways involving of salicylic acid (2-hydroxybenzoic acid), a derivative of benzoic acid.
9697	salicylic acid biosynthetic process	P	The chemical reactions and pathways resulting in the formation of salicylic acid (2-hydroxybenzoic acid), a derivative of benzoic acid.
9698	phenylpropanoid metabolic process	P	The chemical reactions and pathways involving aromatic derivatives of trans-cinnamic acid.
9699	phenylpropanoid biosynthetic process	P	The chemical reactions and pathways resulting in the formation of aromatic derivatives of trans-cinnamic acid.
9700	indole phytoalexin biosynthetic process	P	The chemical reactions and pathways resulting in the formation of indole phytoalexins, any indole compound produced by plants as part of their defense response.
9701	isoflavonoid phytoalexin biosynthetic process	P	The chemical reactions and pathways resulting in the formation of isoflavonoid phytoalexins, a group of water-soluble phenolic derivatives isomeric with flavonoids that possess antibiotic activity and are produced by plant tissues in response to infection.
9702	L-arabinokinase activity	F	Catalysis of the reaction: L-arabinose + ATP = beta-L-arabinose 1-phosphate + ADP + 2 H(+).
9703	nitrate reductase (NADH) activity	F	Catalysis of the reaction: nitrite + NAD+ + H2O = nitrate + NADH + H+.
9704	de-etiolation	P	The greening response of plants grown in the dark (etiolated) as a result of chloroplast biogenesis and the accumulation of chlorophyll.
9705	plant-type vacuole membrane	C	The lipid bilayer surrounding a vacuole that retains the same shape regardless of cell cycle phase. The membrane separates its contents from the cytoplasm of the cell. An example of this component is found in Arabidopsis thaliana.
9706	chloroplast inner membrane	C	The inner, i.e. lumen-facing, lipid bilayer of the chloroplast envelope; also faces the chloroplast stroma.
9707	chloroplast outer membrane	C	The outer, i.e. cytoplasm-facing, lipid bilayer of the chloroplast envelope.
9708	benzyl isoquinoline alkaloid biosynthetic process	P	The chemical reactions and pathways resulting in the formation of benzyl isoquinoline alkaloids, compounds with bicyclic N-containing aromatic rings.
9709	terpenoid indole alkaloid biosynthetic process	P	The chemical reactions and pathways resulting in the formation of terpenoid indole alkaloids, compounds formed from the condensation of tryptamine (derived from tryptophan) and secologanin (derived from geranyl pyrophosphate).
9710	tropane alkaloid biosynthetic process	P	The chemical reactions and pathways resulting in the breakdown of tropane alkaloids, compounds containing the 8-methyl-8-azabicyclo(3.2.1)octane ring system.
9711	purine alkaloid biosynthetic process	P	The chemical reactions and pathways resulting in the breakdown of purine alkaloids, compounds derived from purine and composed of an N-containing double ring structure.
9712	catechol-containing compound metabolic process	P	The chemical reactions and pathways involving a compound containing a pyrocatechol (1,2-benzenediol) nucleus or substituent.
9713	catechol-containing compound biosynthetic process	P	The chemical reactions and pathways resulting in the formation of catechol-containing compounds. Catechol is a compound containing a pyrocatechol nucleus or substituent.
9714	chalcone metabolic process	P	The chemical reactions and pathways involving chalcones, phenyl steryl ketone or its hydroxylated derivatives.
9715	chalcone biosynthetic process	P	The chemical reactions and pathways resulting in the formation of chalcone, phenyl steryl ketone or its hydroxylated derivatives.
9716	flavonoid phytoalexin biosynthetic process	P	The chemical reactions and pathways resulting in the formation of flavonoid phytoalexins, a group of water-soluble phenolic derivatives containing a flavan skeleton, which possess antibiotic activity and are produced by plant tissues in response to infection.
9717	isoflavonoid biosynthetic process	P	The chemical reactions and pathways resulting in the formation of isoflavonoids, a group of water-soluble phenolic derivatives, isomeric with flavonoids.
9718	anthocyanin-containing compound biosynthetic process	P	The chemical reactions and pathways resulting in the formation of anthocyanins, any member of a group of intensely colored soluble glycosides of anthocyanidins.
9719	response to endogenous stimulus	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus arising within the organism.
9720	detection of hormone stimulus	P	The series of events in which a hormone stimulus is received by a cell and converted into a molecular signal.
9721	detection of auxin stimulus	P	The series of events in which an auxin stimulus is received by a cell and converted into a molecular signal.
9722	detection of cytokinin stimulus	P	The series of events in which a cytokinin stimulus is received by a cell and converted into a molecular signal.
9723	response to ethylene	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ethylene (ethene) stimulus.
9724	detection of abscisic acid stimulus	P	The series of events in which an abscisic acid stimulus is received by a cell and converted into a molecular signal.
9725	response to hormone	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hormone stimulus.
9726	detection of endogenous stimulus	P	The series of events in which an endogenous stimulus is received by a cell and converted into a molecular signal.
9727	detection of ethylene stimulus	P	The series of events in which an ethylene (ethene) stimulus is received by a cell and converted into a molecular signal.
9728	detection of gibberellic acid stimulus	P	The series of events in which a gibberellic acid stimulus is received by a cell and converted into a molecular signal.
9729	detection of brassinosteroid stimulus	P	The series of events in which a brassinosteroid stimulus is received by a cell and converted into a molecular signal.
9730	detection of carbohydrate stimulus	P	The series of events in which a carbohydrate stimulus is received by a cell and converted into a molecular signal.
9731	detection of sucrose stimulus	P	The series of events in which a sucrose stimulus is received by a cell and converted into a molecular signal.
9732	detection of hexose stimulus	P	The series of events in which a stimulus from a hexose is received and converted into a molecular signal.
9733	response to auxin	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an auxin stimulus.
9734	auxin-activated signaling pathway	P	A series of molecular signals generated by the binding of the plant hormone auxin to a receptor, and ending with modulation of a downstream cellular process, e.g. transcription.
9735	response to cytokinin	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytokinin stimulus.
9736	cytokinin-activated signaling pathway	P	A series of molecular signals generated by the binding of a cytokinin to a receptor, and ending with regulation of a downstream cellular process, e.g. transcription.
9737	response to abscisic acid	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abscisic acid stimulus.
9738	abscisic acid-activated signaling pathway	P	A series of molecular signals generated by the binding of the plant hormone abscisic acid (ABA) to a receptor, and ending with modulation of a cellular process, e.g. transcription.
9739	response to gibberellin	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gibberellin stimulus.
9740	gibberellic acid mediated signaling pathway	P	A series of molecular signals mediated by the detection of gibberellic acid.
9741	response to brassinosteroid	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a brassinosteroid stimulus.
9742	brassinosteroid mediated signaling pathway	P	A series of molecular signals mediated by the detection of brassinosteroid.
9743	response to carbohydrate	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbohydrate stimulus.
9744	response to sucrose	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sucrose stimulus.
9745	sucrose mediated signaling	P	A series of molecular signals mediated by the detection of sucrose.
9746	response to hexose	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hexose stimulus.
9747	hexokinase-dependent signaling	P	A series of molecular signals mediated by hexose and dependent on the detection of hexokinase.
9748	hexokinase-independent signaling	P	A series of molecular signals mediated by hexose and independent of hexokinase.
9749	response to glucose	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucose stimulus.
9750	response to fructose	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fructose stimulus.
9751	response to salicylic acid	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a salicylic acid stimulus.
9752	detection of salicylic acid stimulus	P	The series of events in which a salicylic acid stimulus is received by a cell and converted into a molecular signal.
9753	response to jasmonic acid	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a jasmonic acid stimulus.
9754	detection of jasmonic acid stimulus	P	The series of events in which a jasmonic acid stimulus is received by a cell and converted into a molecular signal. Series of events required for a jasmonic acid stimulus to be detected and converted to a signal molecule.
9755	hormone-mediated signaling pathway	P	A series of molecular signals mediated by the detection of a hormone.
9756	carbohydrate mediated signaling	P	A series of molecular signals mediated by the detection of carbohydrate.
9757	hexose mediated signaling	P	A series of molecular signals mediated by the detection of hexose.
9758	carbohydrate utilization	P	A series of processes that forms an integrated mechanism by which a cell or an organism detects the depletion of primary carbohydrate sources,usually glucose, and then activates genes to scavenge the last traces of the primary carbohydrate source and to transport and metabolize alternate carbohydrate sources. The utilization process begins when the cell or organism detects carbohydrate levels, includes the activation of genes whose products detect, transport or metabolize carbohydrates, and ends when the carbohydrate is incorporated into the cell or organism's metabolism.
9759	indole glucosinolate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of indole glucosinolates, sulfur-containing compounds that have a common structure linked to an R group derived from tryptophan.
9760	C4 photosynthesis	P	The combination of atmospheric CO2 with a 3-carbon molecule phosphoenol pyruvate (PEP) in the mesophyll cells to make a 4-carbon acid which is immediately converted to malic acid. The malic acid is then passed across to the bundle sheath cells where it is broken down again to pyruvic acid and CO2. The acid is passed back to the mesophyll cells to be used again, while the CO2 is fed into the reductive pentose-phosphate cycle (Calvin cycle) and converted into sugar and starch.
9761	CAM photosynthesis	P	The combination of atmospheric CO2 with a 3-carbon molecule phosphoenol pyruvate (PEP) to make malic acid. The malic acid is then passed into the vacuole where it is stored until daylight, when it is shuttled back out to be used as a substrate in the light reaction of photosynthesis.
9762	NADP-malic enzyme C4 photosynthesis	P	The process of C4 photosynthesis, as it occurs in plants in which the enzyme decarboxylating C4 acids in the bundle sheath is NADP-malic enzyme.
9763	NAD-malic enzyme C4 photosynthesis	P	The process of C4 photosynthesis, as it occurs in plants in which the enzyme decarboxylating C4 acids in the bundle sheath is NAD-malic enzyme.
9764	PEP carboxykinase C4 photosynthesis	P	The process of C4 photosynthesis, as it occurs in plants in which the enzyme decarboxylating C4 acids in the bundle sheath is phosphoenolpyruvate carboxykinase (PEPCK).
9765	photosynthesis, light harvesting	P	Absorption and transfer of the energy absorbed from light photons between photosystem reaction centers.
9766	primary charge separation	P	In the photosynthetic reaction centers, primary charge separation is initiated by the excitation of a molecule followed by the transfer of an electron to an electron acceptor molecule following energy transfer from light harvesting complexes.
9767	photosynthetic electron transport chain	P	A process, occurring as part of photosynthesis, in which light provides the energy for a series of electron carriers to operate together to transfer electrons and generate a transmembrane electrochemical gradient.
9768	photosynthesis, light harvesting in photosystem I	P	After a photon of light is absorbed by one of the many chlorophyll molecules, in one of the light-harvesting complexes of an antenna on photosystem I, some of the absorbed energy is transferred to the pair of chlorophyll molecules in the reaction center.
9769	photosynthesis, light harvesting in photosystem II	P	After a photon of light is absorbed by one of the many chlorophyll molecules, in one of the light-harvesting complexes of an antenna on photosystem II, some of the absorbed energy is transferred to the pair of chlorophyll molecules in the reaction center.
9770	primary charge separation in photosystem I	P	Energized reaction-center P700 chlorophylls on photosystem I donate an electron to a loosely bound Quinone acceptor molecule X, on the stromal surface of the thylakoid membrane. The result is charge separation; a negative charge on the stromal side of the thylakoid membrane and a positive charge on the luminal side.
9771	primary charge separation in photosystem II	P	Energized reaction-center P680 chlorophylls on photosystem II donate an electron to a loosely bound acceptor molecule, the quinone Q, on the stromal surface of the thylakoid membrane. The result is charge separation; a negative charge on the stromal side of the thylakoid membrane and a positive charge on the luminal side.
9772	photosynthetic electron transport in photosystem II	P	A photosynthetic electron transport chain in which electrons move from the primary electron acceptor (Quinone, Q) through a chain of electron transport molecules in the thylakoid membrane until they reach the ultimate electron acceptor of Photosystem II, which is plastocyanin (PC). The electron is then passed to the P700 chlorophyll a molecules of the reaction centre of photosystem I.
9773	photosynthetic electron transport in photosystem I	P	A photosynthetic electron transport chain in which electrons move from the primary electron acceptor (Quinone, X) through a chain of electron transport molecules in the thylakoid membrane until they reach ferredoxin which passes the electron to the ultimate electron acceptor; NADP.
9777	photosynthetic phosphorylation	P	Any metabolic process in which photosynthetic organisms use light energy to convert ADP to ATP without the concomitant reduction of dioxygen (O2) to water that occurs in phosphorylation.
9778	cyclic photosynthetic phosphorylation	P	A photosynthetic phosphorylation process in which ATP synthesis is driven by a proton gradient generated across the thylakoid membrane. Involves only photosystem I.
9779	noncyclic photosynthetic phosphorylation	P	A photosynthetic phosphorylation process in which ATP synthesis is linked to the transport of electrons from water to NADP+ with the production of NADPH and dioxygen (O2). Involves photosystem I and photosystem II.
9780	photosynthetic NADP+ reduction	P	An NADPH regeneration process that contributes to the light reactions of photosynthesis. The light reactions of photosynthesis use energy from photons to generate high-energy electrons. These electrons are used directly to reduce NADP+ to NADPH. NADPH is a relatively stable molecule and can pass on its hydrogen atom to other molecules in chemical reactions.
9782	photosystem I antenna complex	C	The antenna complex of photosystem I. A photosystem has two closely linked components, an antenna containing light-absorbing pigments and a reaction center. Each antenna contains one or more light-harvesting complexes (LHCs).
9783	photosystem II antenna complex	C	The antenna complex of photosystem II. A photosystem has two closely linked components, an antenna containing light-absorbing pigments and a reaction center. Each antenna contains one or more light-harvesting complexes (LHCs).
9784	transmembrane receptor histidine kinase activity	F	Combining with a signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: ATP + a protein-L-histidine = ADP + a protein-L-histidine phosphate.
9785	blue light signaling pathway	P	The series of molecular signals initiated upon sensing of blue light by photoreceptor molecule, at a wavelength between 400nm and 470nm.
9786	regulation of asymmetric cell division	P	Any process that modulates the frequency, rate or extent of asymmetric cell division.
9787	regulation of abscisic acid-activated signaling pathway	P	Any process that modulates the frequency, rate or extent of abscisic acid (ABA) signaling.
9788	negative regulation of abscisic acid-activated signaling pathway	P	Any process that stops, prevents, or reduces the frequency, rate or extent of abscisic acid (ABA) signaling.
9789	positive regulation of abscisic acid-activated signaling pathway	P	Any process that activates or increases the frequency, rate or extent of abscisic acid (ABA) signaling.
9790	embryo development	P	The process whose specific outcome is the progression of an embryo from its formation until the end of its embryonic life stage. The end of the embryonic stage is organism-specific. For example, for mammals, the process would begin with zygote formation and end with birth. For insects, the process would begin at zygote formation and end with larval hatching. For plant zygotic embryos, this would be from zygote formation to the end of seed dormancy. For plant vegetative embryos, this would be from the initial determination of the cell or group of cells to form an embryo until the point when the embryo becomes independent of the parent plant.
9791	post-embryonic development	P	The process whose specific outcome is the progression of the organism over time, from the completion of embryonic development to the mature structure. See embryonic development.
9792	embryo development ending in birth or egg hatching	P	The process whose specific outcome is the progression of an embryo over time, from zygote formation until the end of the embryonic life stage. The end of the embryonic life stage is organism-specific and may be somewhat arbitrary; for mammals it is usually considered to be birth, for insects the hatching of the first instar larva from the eggshell.
9793	embryo development ending in seed dormancy	P	The process whose specific outcome is the progression of the embryo over time, from zygote formation to the end of seed dormancy. An example of this process is found in Arabidopsis thaliana.
9794	regulation of mitotic cell cycle, embryonic	P	Any process that modulates the frequency, rate or extent of replication and segregation of genetic material in the embryo.
9798	axis specification	P	The establishment, maintenance and elaboration of a pattern along a line or around a point.
9799	specification of symmetry	P	The establishment of an organism's body plan or part of an organism such that a similar arrangement in form and relationship of parts around a common axis, or around each side of a plane is created.
9800	cinnamic acid biosynthetic process	P	The chemical reactions and pathways resulting in the formation of cinnamic acid, 3-phenyl-2-propenoic acid.
9801	cinnamic acid ester metabolic process	P	The chemical reactions and pathways involving ester derivatives of cinnamic acid, phenylpropenoic acid.
9802	cinnamic acid ester biosynthetic process	P	The chemical reactions and pathways resulting in the formation of ester derivatives of cinnamic acid, phenylpropenoic acid.
9803	cinnamic acid metabolic process	P	The chemical reactions and pathways involving cinnamic acid, 3-phenyl-2-propenoic acid.
9804	coumarin metabolic process	P	The chemical reactions and pathways involving coumarins, compounds derived from the phenylacrylic skeleton of cinnamic acids.
9805	coumarin biosynthetic process	P	The chemical reactions and pathways resulting in the formation of coumarins, a class of compounds derived from the phenylacrylic skeleton of cinnamic acids.
9806	lignan metabolic process	P	The chemical reactions and pathways involving lignans, any member of a class of plant metabolites related to lignins. Lignans are usually found as phenylpropanoid dimers in which the phenylpropanoid units are linked tail to tail and thus having a 2,3 dibenzylbutane skeleton, but higher oligomers can also exist.
9807	lignan biosynthetic process	P	The chemical reactions and pathways resulting in the formation of lignans, any member of a class of plant metabolites related to lignins. Lignans are usually found as phenylpropanoid dimers in which the phenylpropanoid units are linked tail to tail and thus having a 2,3 dibenzylbutane skeleton, but higher oligomers can also exist.
9808	lignin metabolic process	P	The chemical reactions and pathways involving lignins, a class of polymers of phenylpropanoid units.
9809	lignin biosynthetic process	P	The chemical reactions and pathways resulting in the formation of lignins, a class of polymers formed by the dehydrogenetive radical polymerization of various phenylpropanoid monomers.
9810	stilbene metabolic process	P	The chemical reactions and pathways involving stilbenes, a class of polyketides formed from a molecule of cinnamic acid and three molecules of malonyl-CoA.
9811	stilbene biosynthetic process	P	The chemical reactions and pathways resulting in the formation of stilbenes, a class of polyketide compounds formed from cinnamic acid and three molecules of malonyl CoA.
9812	flavonoid metabolic process	P	The chemical reactions and pathways involving flavonoids, a group of water-soluble phenolic derivatives containing a flavan skeleton including flavones, flavonols and flavanoids, and anthocyanins.
9813	flavonoid biosynthetic process	P	The chemical reactions and pathways resulting in the formation of flavonoids, a group of phenolic derivatives containing a flavan skeleton.
9814	defense response, incompatible interaction	P	A response of a plant to a pathogenic agent that prevents the occurrence or spread of disease.
9815	1-aminocyclopropane-1-carboxylate oxidase activity	F	Catalysis of the reaction: 1-aminocyclopropane-1-carboxylate + L-ascorbate + O(2) = CO(2) + dehydroascorbate + ethylene + 2 H(2)O + hydrogen cyanide. Ethene is also known as ethylene.
9816	defense response to bacterium, incompatible interaction	P	A response of an organism to a bacterium that prevents the occurrence or spread of disease.
9817	defense response to fungus, incompatible interaction	P	A response of an organism to a fungus that prevents the occurrence or spread of disease.
9818	defense response to protozoan, incompatible interaction	P	A response of an organism to a protozoan that prevents the occurrence or spread of disease.
9819	drought recovery	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of prolonged deprivation of water that restores that organism to a normal (non-stressed) condition.
9820	alkaloid metabolic process	P	The chemical reactions and pathways involving alkaloids, nitrogen containing natural products which are not otherwise classified as peptides, nonprotein amino acids, amines, cyanogenic glycosides, glucosinolates, cofactors, phytohormones or primary metabolites (such as purine or pyrimidine bases).
9821	alkaloid biosynthetic process	P	The chemical reactions and pathways resulting in the formation of alkaloids, nitrogen-containing natural products which are not otherwise classified as nonprotein amino acids, amines, peptides, amines, cyanogenic glycosides, glucosinolates, cofactors, phytohormones, or primary metabolite (such as purine or pyrimidine bases).
9822	alkaloid catabolic process	P	The chemical reactions and pathways resulting in the breakdown of alkaloids, nitrogen containing natural products not otherwise classified as peptides, nonprotein amino acids, amines, cyanogenic glycosides, glucosinolates, cofactors, phytohormones or primary metabolites (such as purine or pyrimidine bases).
9823	cytokinin catabolic process	P	The chemical reactions and pathways resulting in the breakdown of cytokinins, a class of adenine-derived compounds that can function in plants as plant growth regulators.
9824	AMP dimethylallyltransferase activity	F	Catalysis of the reaction: AMP + dimethylallyl diphosphate = N(6)-(dimethylallyl)adenosine 5'-phosphate + diphosphate.
9825	multidimensional cell growth	P	The process in which a cell irreversibly increases in size in two or three [spatial] dimensions or along two or three axes.
9826	unidimensional cell growth	P	The process in which a cell irreversibly increases in size in one [spatial] dimension or along one axis, resulting in the morphogenesis of the cell.
9827	plant-type cell wall modification	P	The series of events leading to chemical and structural alterations of an existing cellulose and pectin-containing cell wall that can result in loosening, increased extensibility or disassembly. An example of this is found in Arabidopsis thaliana.
9828	plant-type cell wall loosening	P	The series of events causing chemical and structural alterations of an existing cellulose and pectin-containing cell wall that results in greater extensibility of the wall. An example of this is found in Arabidopsis thaliana.
9829	cell wall modification involved in fruit ripening	P	The series of events resulting in chemical or structural alterations of existing cell walls that contribute to fruit ripening.
9830	cell wall modification involved in abscission	P	A cellular process that results in the breakdown of the cell wall that contributes to the process of abscission.
9831	plant-type cell wall modification involved in multidimensional cell growth	P	The series of events that occur during cell growth that result in chemical or structural changes to existing cell walls of the type composed chiefly of cellulose and pectin. An example of this is found in Arabidopsis thaliana.
9832	plant-type cell wall biogenesis	P	A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cellulose and pectin-containing cell wall. An example of this is found in Arabidopsis thaliana.
9833	plant-type primary cell wall biogenesis	P	A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of cellulose and pectin-containing cell walls that form adjacent to the middle lamella following cell division and during cell expansion. An example of this is found in Arabidopsis thaliana.
9834	plant-type secondary cell wall biogenesis	P	A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of inextensible cellulose- and pectin-containing cell walls that are formed between the plasma membrane and primary cell wall after cell expansion is complete. An example of this is found in Arabidopsis thaliana.
9835	fruit ripening	P	An aging process that has as participant a fruit. Ripening causes changes in one or more characteristics of a fruit (color, aroma, flavor, texture, hardness, cell wall structure) and may make it more attractive to animals and aid in seed dispersal.
9836	fruit ripening, climacteric	P	A fruit ripening process that involves a burst of respiration and ethylene (ethene) evolution at the onset.
9837	fruit ripening, non-climacteric	P	A fruit ripening process that does not involve a respiratory burst.
9838	abscission	P	The controlled shedding of a body part.
9840	chloroplastic endopeptidase Clp complex	C	A Clp endopeptidase complex located in the chloroplast.
9841	mitochondrial endopeptidase Clp complex	C	A Clp endopeptidase complex located in the mitochondrion.
9842	cyanelle	C	A plastid that contains unstacked, phycobilisome-bearing thylakoid membranes and is surrounded by a double membrane with a peptidoglycan layer in the intermembrane space between the two envelope membranes. Cyanelles are characteristic of algae in the class Glaucophyta, and may represent an ancestral form of plastid.
9843	cyanelle thylakoid	C	A thylakoid found in a cyanelle, which is a type of plastid found in certain algae. The cyanelle contains a photosynthetic membrane resembling that of cyanobacteria.
9845	seed germination	P	The physiological and developmental changes that occur in a seed commencing with water uptake (imbibition) and terminating with the elongation of the embryonic axis.
9846	pollen germination	P	The physiological and developmental changes that occur in a heterosporous plant pollen grain, beginning with hydration and terminating with the emergence of the pollen tube through the aperture.
9847	spore germination	P	The physiological and developmental changes that occur in a spore following release from dormancy up to the earliest signs of growth (e.g. emergence from a spore wall).
9848	indoleacetic acid biosynthetic process via tryptophan	P	The chemical reactions and pathways resulting in the formation of indole-3-acetic acid that occurs through metabolism of L-tryptophan.
9849	tryptophan-independent indoleacetic acid biosynthetic process	P	The chemical reactions and pathways resulting in the formation of indoleacetic acid, independent of tryptophan.
9850	auxin metabolic process	P	The chemical reactions and pathways involving auxins, a group of plant hormones that regulate aspects of plant growth.
9851	auxin biosynthetic process	P	The chemical reactions and pathways resulting in the formation of auxins, plant hormones that regulate aspects of plant growth.
9852	auxin catabolic process	P	The chemical reactions and pathways resulting in the breakdown of auxins, a group of plant hormones that regulate aspects of plant growth.
9853	photorespiration	P	A light-dependent catabolic process occurring concomitantly with photosynthesis in plants (especially C3 plants) whereby dioxygen (O2) is consumed and carbon dioxide (CO2) is evolved. The substrate is glycolate formed in large quantities in chloroplasts from 2-phosphoglycolate generated from ribulose 1,5-bisphosphate by the action of ribulose-bisphosphate carboxylase; the glycolate enters the peroxisomes where it is converted by glycolate oxidase to glyoxylate which undergoes transamination to glycine. This then passes into the mitochondria where it is decarboxylated forming one molecule of serine for every two molecules of glycine. This pathway also exists in photosynthetic bacteria.
9854	oxidative photosynthetic carbon pathway	P	The reactions of the C2 pathway bring about the metabolic conversion of two molecules of 2-phosphoglycolate to one molecule of 3-phosphoglycerate, which can be used by the C3 cycle, and one molecule of carbon dioxide (CO2).
9855	determination of bilateral symmetry	P	The establishment of an organism's body plan or part of an organism with respect to a single longitudinal plane. The pattern can either be symmetric, such that the halves are mirror images, or asymmetric where the pattern deviates from this symmetry.
9856	pollination	P	The cascade of biological processes occurring in plants beginning when the pollen lands on the stigma and continuing up to, but not including, fertilization, as defined by sperm-central cell fusion.
9859	pollen hydration	P	The process in which water is taken up by pollen.
9860	pollen tube growth	P	Growth of pollen via tip extension of the intine wall.
9861	jasmonic acid and ethylene-dependent systemic resistance	P	The jasmonic acid and ethylene (ethene) dependent process that confers broad spectrum systemic resistance to disease in response to wounding or a pathogen.
9862	systemic acquired resistance, salicylic acid mediated signaling pathway	P	The series of molecular signals mediated by salicylic acid involved in systemic acquired resistance.
9863	salicylic acid mediated signaling pathway	P	A series of molecular signals mediated by salicylic acid.
9864	induced systemic resistance, jasmonic acid mediated signaling pathway	P	The series of molecular signals mediated by jasmonic acid involved in induced systemic resistance.
9865	pollen tube adhesion	P	The process in which the pollen tube adheres to cells of the stigma and style.
9866	induced systemic resistance, ethylene mediated signaling pathway	P	The series of molecular signals mediated by ethylene (ethene) involved in induced systemic resistance.
9867	jasmonic acid mediated signaling pathway	P	A series of molecular signals mediated by jasmonic acid.
9868	jasmonic acid and ethylene-dependent systemic resistance, jasmonic acid mediated signaling pathway	P	The series of molecular signals mediated by jasmonic acid involved in jasmonic acid/ethylene (ethene) dependent systemic resistance.
9870	defense response signaling pathway, resistance gene-dependent	P	A series of molecular signals that depends upon R-genes and is activated during defense response.
9871	jasmonic acid and ethylene-dependent systemic resistance, ethylene mediated signaling pathway	P	The series of molecular signals mediated by ethylene (ethene) involved in jasmonic acid/ethylene dependent systemic resistance.
9873	ethylene-activated signaling pathway	P	A series of molecular signals generated by the reception of ethylene (ethene, C2H4) by a receptor and ending with modulation of a cellular process, e.g. transcription.
9875	pollen-pistil interaction	P	The interaction between a pollen grain and pistil.
9876	pollen adhesion	P	The process in which pollen deposited on the stigma adheres to cells of the stigma.
9877	nodulation	P	The formation of nitrogen-fixing root nodules on plant roots.
9878	nodule morphogenesis	P	The process in which the anatomical structures of the nodule are generated and organized.
9879	determination of radial symmetry	P	The establishment of an organism's body plan or a part of an organism such that it is symmetric around a central axis.
9880	embryonic pattern specification	P	The process that results in the patterns of cell differentiation that will arise in an embryo.
9881	photoreceptor activity	F	The function of absorbing and responding to incidental electromagnetic radiation, particularly visible light. The response may involve a change in conformation.
9882	blue light photoreceptor activity	F	The function of absorbing and responding to electromagnetic radiation with a wavelength of approximately 400-470nm. The response may involve a change in conformation.
9883	red or far-red light photoreceptor activity	F	The function of absorbing and responding to electromagnetic radiation with a wavelength of approximately 660-730nm. The response may involve a change in conformation.
9884	cytokinin receptor activity	F	Combining with a cytokinin and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
9885	transmembrane histidine kinase cytokinin receptor activity	F	Combining with a cytokinin and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: ATP + a protein-L-histidine = ADP + a protein-L-histidine phosphate.
9886	post-embryonic animal morphogenesis	P	The process, occurring after animal embryonic development, by which anatomical structures are generated and organized.
9887	animal organ morphogenesis	P	Morphogenesis of an animal organ. An organ is defined as a tissue or set of tissues that work together to perform a specific function or functions. Morphogenesis is the process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.
9888	tissue development	P	The process whose specific outcome is the progression of a tissue over time, from its formation to the mature structure.
9889	regulation of biosynthetic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances.
9890	negative regulation of biosynthetic process	P	Any process that stops, prevents, or reduces the rate of the chemical reactions and pathways resulting in the formation of substances.
9891	positive regulation of biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances.
9892	negative regulation of metabolic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism.
9893	positive regulation of metabolic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism.
9894	regulation of catabolic process	P	Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of substances.
9895	negative regulation of catabolic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances.
9896	positive regulation of catabolic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances.
9897	external side of plasma membrane	C	The leaflet of the plasma membrane that faces away from the cytoplasm and any proteins embedded or anchored in it or attached to its surface.
9898	cytoplasmic side of plasma membrane	C	The leaflet the plasma membrane that faces the cytoplasm and any proteins embedded or anchored in it or attached to its surface.
9899	ent-kaurene synthase activity	F	Catalysis of the reaction: ent-copalyl diphosphate = ent-kaur-16-ene + diphosphate.
9900	dehiscence	P	The opening of an anther, fruit or other structure, which permits the escape of reproductive bodies contained within it.
9901	anther dehiscence	P	The dehiscence of an anther to release the pollen grains contained within it.
9902	chloroplast relocation	P	The process in which chloroplasts in photosynthetic cells migrate toward illuminated sites to optimize photosynthesis and move away from excessively illuminated areas to protect the photosynthetic machinery.
9903	chloroplast avoidance movement	P	The relocation process in which chloroplasts in photosynthetic cells avoid strong light and move away from it in order to preserve the photosynthetic machinery.
9904	chloroplast accumulation movement	P	The relocation process in which chloroplasts in photosynthetic cells move toward a brighter area in a cell to optimize photosynthesis.
9905	ent-copalyl diphosphate synthase activity	F	Catalysis of the reaction: all-trans-geranylgeranyl diphosphate = ent-copalyl diphosphate.
9906	response to photoperiod, blue light	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the detection of a blue light photoperiod stimulus. Blue light is electromagnetic radiation with a wavelength of between 440 and 500nm.
9907	response to photoperiod, red light	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a red light photoperiod stimulus. Red light is electromagnetic radiation of wavelength of 580-700nm.
9908	flower development	P	The process whose specific outcome is the progression of the flower over time, from its formation to the mature structure. The flower is the reproductive structure in a plant, and its development begins with the transition of the vegetative or inflorescence meristem into a floral meristem.
9909	regulation of flower development	P	Any process that modulates the frequency, rate or extent of flower development.
9910	negative regulation of flower development	P	Any process that stops, prevents, or reduces the frequency, rate or extent of flower development.
9911	positive regulation of flower development	P	Any process that activates or increases the frequency, rate or extent of flower development.
9912	auditory receptor cell fate commitment	P	The process in which the cellular identity of auditory hair cells is acquired and determined.
9913	epidermal cell differentiation	P	The process in which a relatively unspecialized cell acquires specialized features of an epidermal cell, any of the cells making up the epidermis.
9914	hormone transport	P	The directed movement of hormones into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
9915	phloem sucrose loading	P	The process of loading sucrose into the sieve tube or companion cell of the phloem for long distance transport from source to sink.
9916	alternative oxidase activity	F	Catalysis of the oxidation of ubiquinol by diverting electrons from the standard electron transfer chain, transferring them from ubiquinol to oxygen and generating water as the product.
9917	sterol 5-alpha reductase activity	F	Catalysis of the removal of a C-5 double bond in the B ring of a sterol.
9918	sterol delta7 reductase activity	F	Catalysis of the reaction: 5-dehydroepisterol = 24-methylenecholesterol.
9920	cell plate formation involved in plant-type cell wall biogenesis	P	The cell cycle process in which the cell plate is formed at the equator of the spindle in the dividing cells during early telophase. An example of this is found in Arabidopsis thaliana.
9921	auxin efflux carrier complex	C	The protein complex associated with the plasma membrane of certain plant cells (e.g. root cortex, epidermal cells) that functions to transport auxin out of the cell.
9922	fatty acid elongase activity	F	Catalysis of the reaction: fatty acid (C-16 or longer) + 2-C = fatty acid (C-16 or longer + 2-C).
9923	fatty acid elongase complex	C	A tetrameric complex of four different subunits which catalyzes the elongation of fatty acids chains 2 carbon units at a time in the synthesis of very long chain fatty acids.
9924	octadecanal decarbonylase activity	F	Catalysis of the reaction: octadecanal = heptadecane + CO.
9925	basal plasma membrane	C	The region of the plasma membrane located at the basal end of the cell. Often used in reference to animal polarized epithelial membranes, where the basal membrane is the part attached to the extracellular matrix, or in plant cells, where the basal membrane is defined with respect to the zygotic axis.
9926	auxin polar transport	P	The unidirectional movement of auxin in the stem from tip to base along the vector of gravity or basipetally.
9927	histidine phosphotransfer kinase activity	F	Serves as a phospho-His intermediate enabling the transfer of phospho group between a hybrid kinase and a response regulator.
9930	longitudinal side of cell surface	C	The side of the cell parallel to the zygotic axis.
9931	calcium-dependent protein serine/threonine kinase activity	F	Catalysis of the reactions: ATP + a protein serine = ADP + protein serine phosphate; and ATP + a protein threonine = ADP + protein threonine phosphate. These reactions are dependent on the presence of calcium ions.
9932	cell tip growth	P	Growth that occurs specifically at the tip of a cell.
9933	meristem structural organization	P	Organization of a region of tissue in a plant that is composed of one or more undifferentiated cells capable of undergoing mitosis and differentiation, thereby effecting growth and development of a plant by giving rise to more meristem or specialized tissue.
9934	regulation of meristem structural organization	P	Any process that modulates the frequency, rate or extent of meristem organization.
9937	regulation of gibberellic acid mediated signaling pathway	P	Any process that modulates the frequency, rate or extent of gibberellic acid mediated signaling.
9938	negative regulation of gibberellic acid mediated signaling pathway	P	Any process that stops, prevents, or reduces the frequency, rate or extent of gibberellic acid mediated signaling activity.
9939	positive regulation of gibberellic acid mediated signaling pathway	P	Any process that activates or increases the frequency, rate or extent of gibberellic acid mediated signaling activity.
9940	amino-terminal vacuolar sorting propeptide binding	F	Interacting selectively and non-covalently with an amino terminal propeptide, which functions as a sorting signal to sort away the soluble vacuolar protein from Golgi to lytic vacuole via clathrin-coated vesicles.
9941	chloroplast envelope	C	The double lipid bilayer enclosing the chloroplast and separating its contents from the rest of the cytoplasm; includes the intermembrane space.
9942	longitudinal axis specification	P	The establishment, maintenance and elaboration of the longitudinal axis. In plants, this is the axis that runs from the shoot to the root.
9943	adaxial/abaxial axis specification	P	The establishment, maintenance and elaboration of the adaxial / abaxial axis. Adaxial refers to being situated toward an axis of an anatomical structure. Abaxial refers to being situated away from an axis of an anatomical structure.
9944	polarity specification of adaxial/abaxial axis	P	The process resulting in the establishment of polarity along the adaxial/abaxial axis. Adaxial refers to being situated toward an axis of an anatomical structure. Abaxial refers to being situated away from an axis of an anatomical structure.
9945	radial axis specification	P	The establishment, maintenance and elaboration of an axis that initiates at a point and radiates outward from the point.
9946	proximal/distal axis specification	P	The establishment, maintenance and elaboration of the proximal/distal axis. The proximal/distal axis is defined by a line that runs from main body (proximal end) of an organism outward (distal end).
9947	centrolateral axis specification	P	The establishment, maintenance and elaboration of the centrolateral axis. In plants, this axis is duplicated and runs from the midrib to the margin of the leaf.
9948	anterior/posterior axis specification	P	The establishment, maintenance and elaboration of the anterior/posterior axis. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism.
9949	polarity specification of anterior/posterior axis	P	Any process resulting in the establishment of polarity along the anterior/posterior axis.
9950	dorsal/ventral axis specification	P	The establishment, maintenance and elaboration of the dorsal/ventral axis. The dorsal/ventral axis is defined by a line that runs orthogonal to both the anterior/posterior and left/right axes. The dorsal end is defined by the upper or back side of an organism. The ventral end is defined by the lower or front side of an organism.
9951	polarity specification of dorsal/ventral axis	P	Any process resulting in the establishment of polarity along the dorsal/ventral axis.
9952	anterior/posterior pattern specification	P	The regionalization process in which specific areas of cell differentiation are determined along the anterior-posterior axis. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism.
9953	dorsal/ventral pattern formation	P	The regionalization process in which the areas along the dorsal/ventral axis are established that will lead to differences in cell differentiation. The dorsal/ventral axis is defined by a line that runs orthogonal to both the anterior/posterior and left/right axes. The dorsal end is defined by the upper or back side of an organism. The ventral end is defined by the lower or front side of an organism.
9954	proximal/distal pattern formation	P	The regionalization process in which specific areas of cell differentiation are determined along a proximal/distal axis. The proximal/distal axis is defined by a line that runs from main body (proximal end) of an organism outward (distal end).
9955	adaxial/abaxial pattern specification	P	The regionalization process in which differences in cell differentiation along the adaxial/abaxial are generated. Adaxial refers to being situated toward an axis of an anatomical structure. Abaxial refers to being situated away from an axis of an anatomical structure.
9956	radial pattern formation	P	The regionalization process that results in defined areas around a point in which specific types of cell differentiation will occur.
9957	epidermal cell fate specification	P	The process in which a cell becomes capable of differentiating autonomously into an epidermal cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.
9958	positive gravitropism	P	The orientation of plant parts towards gravity.
9959	negative gravitropism	P	The orientation of plant parts away from gravity.
9960	endosperm development	P	The process whose specific outcome is the progression of the endosperm over time, from its formation to the mature structure. The endosperm is formed during fertilization and provides nutrients to the developing embryo.
9961	response to 1-aminocyclopropane-1-carboxylic acid	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 1-aminocyclopropane-1-carboxylic acid stimulus.
9962	regulation of flavonoid biosynthetic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of flavonoids.
9963	positive regulation of flavonoid biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of flavonoids.
9964	negative regulation of flavonoid biosynthetic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of flavonoids.
9965	leaf morphogenesis	P	The process in which the anatomical structures of the leaf are generated and organized.
9966	regulation of signal transduction	P	Any process that modulates the frequency, rate or extent of signal transduction.
9967	positive regulation of signal transduction	P	Any process that activates or increases the frequency, rate or extent of signal transduction.
9968	negative regulation of signal transduction	P	Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction.
9969	xyloglucan biosynthetic process	P	The chemical reactions and pathways resulting in the formation of xyloglucan, the cross-linking glycan composed of (1->4)-beta-D glucan backbone substituted at regular intervals with beta-D-xylosyl-(1->6) residues, which is present in the primary cell wall of most higher plants.
9970	cellular response to sulfate starvation	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of sulfate.
9971	anastral spindle assembly involved in male meiosis	P	The aggregation, arrangement and bonding together of a set of components to form the anastral spindle in male meiotic cells.
9972	cytidine deamination	P	The removal of amino group in the presence of water.
9973	adenylyl-sulfate reductase activity	F	Catalysis of the reaction: AMP + sulfite + acceptor = adenylyl sulfate + reduced acceptor.
9974	zeinoxanthin epsilon hydroxylase activity	F	Catalysis of the reaction: zeinoxanthin + NADPH + O2 + H+ = lutein + NADP+ + H2O. Adds a hydroxyl group to the epsilon ring of the alpha-carotene.
9975	cyclase activity	F	Catalysis of a ring closure reaction.
9976	tocopherol cyclase activity	F	Catalysis of the reaction: alkene group + alcohol group on same molecule = cyclic ether. Substrates are 2-methyl-6-phytyl-1,4- hydroquinone (forms delta-tocopherol) and 2,3-dimethyl-5-phytyl-1,4-hydroquinone (forms gamma-tocopherol).
9977	proton motive force dependent protein transmembrane transporter activity	F	Catalysis of the transfer of proteins from one side of the membrane to the other. Transportation is dependent on pH gradient across the membrane.
9978	allene oxide synthase activity	F	Catalysis of the reaction: 13(S)-hydroperoxylinolenate = 12,13(S)-epoxylinolenate + H2O.
9979	16:0 monogalactosyldiacylglycerol desaturase activity	F	Catalysis of the introduction of an omega-3 double bond into an unsaturated 16-carbon fatty acid in a monogalactosyldiacylglycerol molecule.
9982	pseudouridine synthase activity	F	Catalysis of the reaction: RNA uridine = RNA pseudouridine. Conversion of uridine in an RNA molecule to pseudouridine by rotation of the C1'-N-1 glycosidic bond of uridine in RNA to a C1'-C5.
9986	cell surface	C	The external part of the cell wall and/or plasma membrane.
9987	cellular process	P	Any process that is carried out at the cellular level, but not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
9988	cell-cell recognition	P	Cell recognition between cells. May involve the formation of specialized cell junctions.
9989	cell-matrix recognition	P	Cell recognition that involves the interaction of the cell with the extracellular matrix.
9990	contact guidance	P	Cell recognition involving the deposition of specific pathways in the extracellular matrix that guide migrating cells.
9991	response to extracellular stimulus	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an extracellular stimulus.
9992	cellular water homeostasis	P	Any process involved in the maintenance of an internal steady state of water within a cell.
9994	oocyte differentiation	P	The process in which a relatively unspecialized immature germ cell acquires the specialized features of a mature female gamete.
9995	soluble molecule recognition	P	The recognition of soluble molecules in the environment.
9996	negative regulation of cell fate specification	P	Any process that restricts, stops or prevents a cell from adopting a specific cell fate.
9997	negative regulation of cardioblast cell fate specification	P	Any process that restricts, stops or prevents a cell from specifying into a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.
9998	negative regulation of retinal cone cell fate specification	P	Any process that restricts, stops or prevents a cell from specifying into a retinal cone cell.
9999	negative regulation of auditory receptor cell fate specification	P	Any process that restricts, stops or prevents a cell from specifying into an auditory hair cell.
10001	glial cell differentiation	P	The process in which a relatively unspecialized cell acquires the specialized features of a glial cell.
10002	cardioblast differentiation	P	The process in which a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.
10004	gastrulation involving germ band extension	P	A complex and coordinated series of cellular movements, including germ band extension, that occurs at the end of cleavage during embryonic development. An example of this process is found in Drosophila melanogaster.
10005	cortical microtubule, transverse to long axis	C	Arrays of microtubules underlying and connected to the plasma membrane, in the cortical cytosol, oriented mainly with their axes transverse to the long axis of the cell (and root in plants). In plants it influences the direction of cellulose microfibril deposition.
10006	Toc complex	C	Protein translocon complex at the chloroplast outer membrane.
10007	magnesium chelatase complex	C	A heterotrimeric enzyme complex composed of three subunits, all of which are required for enzyme activity, which catalyzes the chelation of Mg by proto IX in an ATP-dependent manner.
10008	endosome membrane	C	The lipid bilayer surrounding an endosome.
10009	cytoplasmic side of endosome membrane	C	The side (leaflet) of the endosome membrane that faces the cytoplasm.
10011	auxin binding	F	Interacting selectively and non-covalently with auxin, plant hormones that regulate aspects of plant growth.
10012	steroid 22-alpha hydroxylase activity	F	Catalysis of the reaction: 5-alpha-campestanaol + O2 = 6-deoxocathasterone + H2O.
10013	N-1-naphthylphthalamic acid binding	F	Interacting selectively and non-covalently with N-1-naphthylphthalamic acid, an auxin transport inhibitor.
10014	meristem initiation	P	Initiation of a region of tissue in a plant that is composed of one or more undifferentiated cells capable of undergoing mitosis and differentiation, thereby effecting growth and development of a plant by giving rise to more meristem or specialized tissue.
10015	root morphogenesis	P	The process in which the anatomical structures of roots are generated and organized. The root is the usually underground part of a seed plant body that originates from the hypocotyl, functions as an organ of absorption, aeration, and food storage or as a means of anchorage and support.
10016	shoot system morphogenesis	P	The process in which the anatomical structures of the shoot are generated and organized. The shoot is the part of a seed plant body that is usually above ground.
10017	red or far-red light signaling pathway	P	The series of molecular signals initiated upon sensing by photoreceptor molecules of red light or far red light. Red light is electromagnetic radiation of wavelength of 580-700nm. Far red light is electromagnetic radiation of wavelength 700-800nm. An example of this response is seen at the beginning of many plant species developmental stages. These include germination, and the point when cotyledon expansion is triggered. In certain species these processes take place in response to absorption of red light by the pigment molecule phytochrome, but the signal can be reversed by exposure to far red light. During the initial phase the phytochrome molecule is only present in the red light absorbing form, but on absorption of red light it changes to a far red light absorbing form, triggering progress through development. An immediate short period of exposure to far red light entirely returns the pigment to its initial state and prevents triggering of the developmental process. A thirty minute break between red and subsequent far red light exposure renders the red light effect irreversible, and development then occurs regardless of whether far red light exposure subsequently occurs.
10018	far-red light signaling pathway	P	The series of molecular signals initiated upon sensing of far red light by a photoreceptor molecule. Far red light is electromagnetic radiation of wavelength 700-800nm. An example of this response is seen at the beginning of many plant species developmental stages. These include germination, and the point when cotyledon expansion is triggered. In certain species these processes take place in response to absorption of red light by the pigment molecule phytochrome, but the signal can be reversed by exposure to far red light. During the initial phase the phytochrome molecule is only present in the red light absorbing form, but on absorption of red light it changes to a far red light absorbing form, triggering progress through development. An immediate short period of exposure to far red light entirely returns the pigment to its initial state and prevents triggering of the developmental process. A thirty minute break between red and subsequent far red light exposure renders the red light effect irreversible, and development then occurs regardless of whether far red light exposure subsequently occurs.
10019	chloroplast-nucleus signaling pathway	P	The process in which a molecular signal is transduced between the chloroplast and nucleus, such that expression of nuclear encoding photosynthetic proteins is coupled with chloroplast biogenesis.
10020	chloroplast fission	P	The division of a chloroplast within a cell to form two or more separate chloroplast compartments. This division occurs independently of mitosis.
10021	amylopectin biosynthetic process	P	The chemical reactions and pathways resulting in the formation of amylopectin, the (1->4) linked alpha glucose units with alpha-(1->6) linkages.
10022	meristem determinacy	P	The process in which a meristem becomes determinate (i.e. ceases to produce lateral organs and may or may not terminally differentiate).
10023	proanthocyanidin biosynthetic process	P	The chemical reactions and pathways resulting in the formation of proanthocyanidin.
10024	phytochromobilin biosynthetic process	P	The chemical reactions and pathways resulting in the formation of phytochromobilin, which involves the oxidative cleavage of heme by a heme oxygenase(HO) to form biliverdin IX alpha.
10025	wax biosynthetic process	P	The chemical reactions and pathways resulting in the formation of wax, which includes C16 and C18 fatty acids.
10026	trichome differentiation	P	The process in which a relatively unspecialized epidermal cell acquires the specialized features of a trichome cell. An example of this process is found in Arabidopsis thaliana.
10027	thylakoid membrane organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the thylakoid membrane.
10028	xanthophyll cycle	P	A cyclic series of interconversions involving three xanthophylls, violoxanthin, antheraxanthin, and zeaxanthin. The xanthophyll cycle is involved in regulating energy dissipation in light harvesting complex II.
10029	regulation of seed germination	P	Any process that modulates the frequency, rate or extent of seed germination.
10030	positive regulation of seed germination	P	Any process that activates or increase the rate of seed germination.
10031	circumnutation	P	The organismal movement by which the tip of a plant organ follows a spiral pattern as a consequence of growth.
10032	meiotic chromosome condensation	P	Compaction of chromatin structure prior to meiosis in eukaryotic cells.
10033	response to organic substance	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic substance stimulus.
10034	response to acetate	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acetate stimulus.
10035	response to inorganic substance	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an inorganic substance stimulus.
10036	response to boron-containing substance	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a boron-containing substance stimulus.
10037	response to carbon dioxide	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbon dioxide (CO2) stimulus.
10038	response to metal ion	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a metal ion stimulus.
10039	response to iron ion	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iron ion stimulus.
10040	response to iron(II) ion	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iron(II) ion stimulus.
10041	response to iron(III) ion	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iron(III) ion stimulus.
10042	response to manganese ion	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a manganese ion stimulus.
10043	response to zinc ion	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a zinc ion stimulus.
10044	response to aluminum ion	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an aluminum ion stimulus.
10045	response to nickel cation	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nickel cation stimulus.
10046	response to mycotoxin	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mycotoxin stimulus. A mycotoxin is a toxic chemical substance produced by fungi.
10047	fruit dehiscence	P	The process leading to the spontaneous opening of the fruit permitting the escape of seeds.
10048	vernalization response	P	The process of thermal induction in plants in which flowering is promoted by exposure to low temperatures.
10049	acquisition of plant reproductive competence	P	The process in which a plant acquires the ability to respond to a floral inductive signal.
10050	vegetative phase change	P	Any process involved in the transition of a plant from a juvenile phase of vegetative development to an adult phase of vegetative development.
10051	xylem and phloem pattern formation	P	The regionalization process that gives rise to the patterning of the conducting tissues. An example of this process is found in Arabidopsis thaliana.
10052	guard cell differentiation	P	The process in which a guard mother cell acquires the specialized features of a guard cell.
10053	root epidermal cell differentiation	P	The process in which a relatively unspecialized cell in the root epidermis acquires the specialized features of a trichoblast or atrichoblast.
10054	trichoblast differentiation	P	The process in which a relatively unspecialized cell acquires the specialized features of a trichoblast, a root epidermal cell that will give rise to a root hair.
10055	atrichoblast differentiation	P	The process in which a relatively unspecialized cell acquires the specialized features of an atrichoblast, a root epidermal cell that will not give rise to a root hair.
10056	atrichoblast fate specification	P	The process involved in the specification of an atrichoblast.
10057	trichoblast fate specification	P	The process involved in the specification of a trichoblast.
10058	regulation of atrichoblast fate specification	P	Any process that modulates atrichoblast fate specification.
10059	positive regulation of atrichoblast fate specification	P	Any process that induces or promotes atrichoblast fate specification.
10060	negative regulation of atrichoblast fate specification	P	Any process that suppresses atrichoblast fate specification.
10061	regulation of trichoblast fate specification	P	Any process that modulates trichoblast fate specification.
10062	negative regulation of trichoblast fate specification	P	Any process that suppresses trichoblast fate specification.
10063	positive regulation of trichoblast fate specification	P	Any process that induces or promotes trichoblast fate specification.
10064	embryonic shoot morphogenesis	P	The process in which the anatomical structures of embryonic shoot are generated and organized.
10065	primary meristem tissue development	P	The process whose specific outcome is the progression of the primary meristem over time, from formation to the mature structure, as it occurs during plant embryogenesis. The primary meristem tissue is the protoderm, ground meristem and procambium.
10066	ground meristem histogenesis	P	The formation of the primary meristem or meristematic tissue that gives rise to the ground tissues.
10067	procambium histogenesis	P	The formation of the primary meristem or meristematic tissue that gives rise to the primary vascular tissue.
10068	protoderm histogenesis	P	The formation of the primary meristem or meristematic tissue that gives rise to the epidermis.
10069	zygote asymmetric cytokinesis in embryo sac	P	The division of the zygote in a plane perpendicular to the long axis of the embryo sac to produce a larger basal cell near the micropyle and a small terminal cell close to what was the central cell and is now the developing endosperm. An example of this process is found in Arabidopsis thaliana.
10070	zygote asymmetric cell division	P	The division of the zygote into two daughter cells that will adopt developmentally distinct potentials.
10071	root meristem specification	P	The specification of a meristem which will give rise to a primary or lateral root.
10072	primary shoot apical meristem specification	P	The specification of the meristem which will give rise to all post-embryonic above-ground structures of the plant as well as the non-root below-ground structures, such as rhizomes and tubers.
10073	meristem maintenance	P	Any process involved in maintaining the identity, size and shape of a meristem.
10074	maintenance of meristem identity	P	The process in which an organism retains a population of meristem cells, preventing the commitment of all stem cell progeny to a differentiated cell fate.
10075	regulation of meristem growth	P	Any process involved in maintaining the size and shape of a meristem.
10076	maintenance of floral meristem identity	P	The process in which an organism retains a population of floral meristem cells, preventing the commitment of all stem cell progeny to a differentiated cell fate.
10077	maintenance of inflorescence meristem identity	P	The process in which an organism retains a population of inflorescence meristem cells, preventing the commitment of all stem cell progeny to a differentiated cell fate.
10078	maintenance of root meristem identity	P	The process in which an organism retains a population of root meristem cells, preventing the commitment of all stem cell progeny to a differentiated cell fate.
10079	maintenance of vegetative meristem identity	P	The process in which an organism retains a population of vegetative meristem cells, preventing the commitment of all stem cell progeny to a differentiated cell fate.
10080	regulation of floral meristem growth	P	Any process involved in maintaining the size and shape of a floral meristem.
10081	regulation of inflorescence meristem growth	P	Any process involved in maintaining the size and shape of an inflorescence meristem.
10082	regulation of root meristem growth	P	Any process involved in maintaining the size and shape of a root meristem.
10083	regulation of vegetative meristem growth	P	Any process involved in maintaining the size and shape of a vegetative meristem.
10084	specification of animal organ axis polarity	P	The process in which the polarity of an animal organ axis is specified.
10085	polarity specification of proximal/distal axis	P	Any process resulting in the establishment of polarity along the proximal/distal axis.
10086	embryonic root morphogenesis	P	The process in which the anatomical structures of the embryonic root are generated and organized.
10087	phloem or xylem histogenesis	P	The process whose specific outcome is the progression of phloem and/or xylem over time, from formation to the mature structure. An example of this process is found in Arabidopsis thaliana.
10088	phloem development	P	The formation of the principal food-conducting tissue of a vascular plant.
10089	xylem development	P	The formation of the principal water-conducting tissue of a vascular plant.
10090	trichome morphogenesis	P	The process in which the structures of a hair cell (trichome) cell are generated and organized. This process occurs while the initially relatively unspecialized epidermal cell is acquiring the specialized features of a hair cell. An example of this process is found in Arabidopsis thaliana.
10091	trichome branching	P	Any process involved in the formation of branches in plant hair cells. An example of this process is found in Arabidopsis thaliana.
10092	specification of animal organ identity	P	The regionalization process in which the identity of an animal organ primordium is specified. Identity is considered to be the aggregate of characteristics by which a structure is recognized.
10093	specification of floral organ identity	P	The process in which the identity of a floral organ primordium is specified. Identity is considered to be the aggregate of characteristics by which a structure is recognized.
10094	specification of carpel identity	P	The process in which a floral organ primordium acquires the carpel identity. Identity is considered to be the aggregate of characteristics by which a structure is recognized.
10095	specification of petal identity	P	The process in which a floral organ primordium acquires petal identity. Identity is considered to be the aggregate of characteristics by which a structure is recognized.
10096	specification of sepal identity	P	The process in which a floral organ primordium acquires sepal identity. Identity is considered to be the aggregate of characteristics by which a structure is recognized.
10097	specification of stamen identity	P	The process in which a floral organ primordium acquires stamen or staminode identity. Identity is considered to be the aggregate of characteristics by which a structure is recognized.
10098	suspensor development	P	The process whose specific outcome is the progression of the suspensor over time, from its formation to the mature structure. The suspensor is the extension at the base of the embryo that anchors the embryo in the embryo sac and pushes it into the endosperm.
10099	regulation of photomorphogenesis	P	Any process that modulates the rate or extent of photomorphogenesis.
10100	negative regulation of photomorphogenesis	P	Any process that stops, reduces or prevents photomorphogenesis.
10101	post-embryonic root morphogenesis	P	The process in which the anatomical structures of the post-embryonic root are generated and organized. The post-embryonic root is the root formed after the embryonic phase has been completed.
10102	lateral root morphogenesis	P	The process in which the anatomical structures of a lateral root are generated and organized. A lateral root is one formed from pericycle cells located on the xylem radius of the root, as opposed to the initiation of the main root from the embryo proper.
10103	stomatal complex morphogenesis	P	The process in which the anatomical structures of the stomatal complex are generated and organized. The stomatal complex is the stomatal guard cells and their associated epidermal cells.
10104	regulation of ethylene-activated signaling pathway	P	Any process that modulates the frequency, rate or extent of ethylene (ethene) signal transduction.
10105	negative regulation of ethylene-activated signaling pathway	P	Any process that stops or prevents ethylene (ethene) signal transduction.
10106	cellular response to iron ion starvation	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of iron ions.
10107	potassium ion import	P	The directed movement of potassium ions into a cell or organelle.
10108	detection of glutamine	P	The series of events in which a glutamine stimulus is received by a cell and converted into a molecular signal.
10109	regulation of photosynthesis	P	Any process that modulates the frequency, rate or extent of photosynthesis.
10110	regulation of photosynthesis, dark reaction	P	Any process that modulates the frequency, rate or extent of photosynthesis dark reaction.
10111	glyoxysome organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the glyoxysome. A glyoxysome is a microbody that contains the enzymes of the glyoxylate pathway.
10112	regulation of systemic acquired resistance	P	Any process that modulates the frequency, rate or extent of systemic acquired resistance.
10113	negative regulation of systemic acquired resistance	P	Any process that stops, prevents, or reduces the frequency, rate or extent of systemic acquired resistance.
10114	response to red light	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a red light stimulus. Red light is electromagnetic radiation of wavelength of 580-700nm. An example of this response is seen at the beginning of many plant species developmental stages. These include germination, and the point when cotyledon expansion is triggered. In certain species these processes take place in response to absorption of red light by the pigment molecule phytochrome, but the signal can be reversed by exposure to far red light. During the initial phase the phytochrome molecule is only present in the red light absorbing form, but on absorption of red light it changes to a far red light absorbing form, triggering progress through development. An immediate short period of exposure to far red light entirely returns the pigment to its initial state and prevents triggering of the developmental process. A thirty minute break between red and subsequent far red light exposure renders the red light effect irreversible, and development then occurs regardless of whether far red light exposure subsequently occurs.
10115	regulation of abscisic acid biosynthetic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of abscisic acid.
10116	positive regulation of abscisic acid biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of abscisic acid.
10117	photoprotection	P	Protection mechanism used by plants under conditions of excess energy absorption as a consequence of the light reactions of photosynthesis.
10118	stomatal movement	P	The process of opening or closing of stomata, which is directly related to the stomatal conductance (measuring rate of passage of either water vapor or carbon dioxide (CO2) through stomata).
10119	regulation of stomatal movement	P	Any process that modulates the frequency, rate or extent of stomatal movement.
10120	camalexin biosynthetic process	P	The chemical reactions and pathways resulting in the formation of camalexin, an indole phytoalexin.
10121	arginine catabolic process to proline via ornithine	P	The chemical reactions and pathways resulting in the breakdown of arginine into other compounds, including proline, via ornithine.
10122	arginine catabolic process to alanine via ornithine	P	The chemical reactions and pathways resulting in the breakdown of arginine into other compounds, including alanine, via ornithine.
10123	acetate catabolic process to butyrate, ethanol, acetone and butanol	P	The anaerobic chemical reactions and pathways resulting in the breakdown of acetate to form butyrate, ethanol, acetone and butanol.
10124	phenylacetate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of phenylacetate.
10125	mycothiol biosynthetic process	P	The chemical reactions and pathways resulting in the formation of mycothiol, which consists of N-acetyl-L-cysteine linked to a pseudodisaccharide, D-glucosamine and myo-inositol. Mycothiol is produced in actinomycetes like mycobacteria and serves similar functions to glutathione.
10126	mycothiol metabolic process	P	The chemical reactions and pathways involving mycothiol, which consists of N-acetyl-L-cysteine linked to a pseudodisaccharide, D-glucosamine and myo-inositol. Mycothiol is produced in actinomycetes like mycobacteria and serves similar functions to glutathione.
10127	mycothiol-dependent detoxification	P	The chemical reactions using mycothiol to convert an alkylating agent to an S-conjugate of mycothiol. The latter is cleaved to release mercapturic acid which is excreted from the cell.
10128	benzoate catabolic process via CoA ligation	P	The chemical reactions and pathways resulting in the breakdown of benzoate, by its ligation to Coenzyme A to form benzoyl-CoA, which is then broken by an aerobic or anaerobic pathway.
10129	anaerobic cyclohexane-1-carboxylate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of cyclohexane-1-carboxylate, a alicyclic acid, in the absence of oxygen.
10130	anaerobic ethylbenzene catabolic process	P	The chemical reactions and pathways resulting in the breakdown of ethylbenzene, a benzene derivative with an ethyl group attached to the ring, which occurs in the absence of oxygen.
10132	dhurrin biosynthetic process	P	The chemical reactions and pathways resulting in the formation of dhurrin, a cyanogenic glucoside which functions as a plant defense compound.
10133	proline catabolic process to glutamate	P	The chemical reactions and pathways resulting in the breakdown of proline into other compounds, including glutamate.
10134	sulfate assimilation via adenylyl sulfate reduction	P	The pathway by which inorganic sulfate is activated, reduced and incorporated into sulfated compounds, where the activated sulfate, adenylyl-sulfate, is reduced to sulfite by the activity of adenylyl-sulfate reductase.
10135	ureide metabolic process	P	The chemical reactions and pathways involving ureide, allantoin and allantoate, which are the organic forms of nitrogen in nitrogen fixing and transporting plants.
10136	ureide catabolic process	P	The chemical reactions and pathways resulting in the breakdown of ureide, which is the organic form of nitrogen in nitrogen fixing and transporting plants with the release of ammonium.
10137	ureide biosynthetic process	P	The chemical reactions and pathways resulting in the formation of ureide, the organic form of nitrogen in nitrogen fixing and transporting plants, from IMP, which is synthesized de novo during nitrogen fixation by roots.
10138	pyrimidine ribonucleotide salvage	P	The pathway by which pyrimidine bases or pyrimidine ribonucleosides from pyrimidine nucleotide breakdown are converted back to pyrimidine ribonucleotides. The salvage pathway is important where there is no de novo pyrimidine nucleotide biosynthesis.
10139	pyrimidine deoxyribonucleotide salvage	P	The pathway by which pyrimidine bases or pyrimidine deoxyribonucleotides from pyrimidine nucleotide breakdown are converted back to pyrimidine deoxyribonucleotides. The salvage pathway is important where there is no de novo pyrimidine deoxyribonucleotide biosynthesis.
10142	farnesyl diphosphate biosynthetic process, mevalonate pathway	P	The pathway that converts acetate, in the form of acetyl-CoA, to farnesyl diphosphate (FPP) through a series of mevalonate intermediates. Farnesyl diphosphate is an important substrate for other essential pathways, such as biosynthesis of sterols.
10143	cutin biosynthetic process	P	The chemical reactions and pathways resulting in the formation of cutin, a waxy substance, which combined with cellulose forms a substance nearly impervious to water and constituting the cuticle in plants.
10144	pyridoxal phosphate biosynthetic process from pyridoxamine	P	The chemical reactions and pathways resulting in the formation of pyridoxal phosphate, the active form of vitamin B6, from pyridoxamine.
10145	fructan metabolic process	P	The chemical reactions and pathways involving fructan, a polysaccharide consisting of fructose residues.
10146	fructan biosynthetic process	P	The chemical reactions and pathways resulting in the formation of fructan a polysaccharide consisting of fructose residues.
10147	fructan catabolic process	P	The chemical reactions and pathways resulting in the breakdown of fructan, a polysaccharide consisting of fructose residues.
10148	transpiration	P	Release of water by the plant into the air as water vapor mainly through leaves.
10150	leaf senescence	P	The process that occurs in a leaf near the end of its active life that is associated with the dismantling of cell components and membranes, loss of functional chloroplasts, and an overall decline in metabolism.
10151	chloroplast elongation	P	Expansion of the chloroplast that usually precedes division.
10152	pollen maturation	P	The final stages of microgametogenesis after the trinucleate stage has been reached resulting in viable pollen grains.
10154	fruit development	P	The process whose specific outcome is the progression of the fruit over time, from its formation to the mature structure. The fruit is a reproductive body of a seed plant.
10155	regulation of proton transport	P	Any process that modulates the frequency, rate or extent of proton transport into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
10157	response to chlorate	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chlorate stimulus.
10158	abaxial cell fate specification	P	The process in which a cell becomes capable of differentiating autonomously into an abaxial cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.
10159	specification of animal organ position	P	The regionalization process in which information that determines the correct position at which animal organ primordia are formed is generated and perceived resulting in correct positioning of the new animal organ.
10160	formation of animal organ boundary	P	The regionalization process that specifies animal organ primordium boundaries resulting in a restriction of organogenesis to a limited spatial domain and keeping the organ separate from surrounding tissues.
10161	red light signaling pathway	P	The series of molecular signals initiated upon sensing of red light by a photoreceptor molecule. Red light is electromagnetic radiation of wavelength of 580-700nm. An example of this response is seen at the beginning of many plant species developmental stages. These include germination, and the point when cotyledon expansion is triggered. In certain species these processes take place in response to absorption of red light by the pigment molecule phytochrome, but the signal can be reversed by exposure to far red light. During the initial phase the phytochrome molecule is only present in the red light absorbing form, but on absorption of red light it changes to a far red light absorbing form, triggering progress through development. An immediate short period of exposure to far red light entirely returns the pigment to its initial state and prevents triggering of the developmental process. A thirty minute break between red and subsequent far red light exposure renders the red light effect irreversible, and development then occurs regardless of whether far red light exposure subsequently occurs.
10162	seed dormancy process	P	A dormancy process in which dormancy (sometimes called a dormant state) is induced, maintained or broken in a seed. Seed dormancy is a suspension of most physiological activity and growth in a seed, including the embryo contained therein, that can be reactivated. It often requires special conditions for reactivation, such as specific temperature, scarification, or leaching of inhibitors.
10163	high-affinity potassium ion import	P	The directed, energized, high affinity movement of potassium ions into a cell or organelle, driven by cation symport with hydrogen or sodium ions. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.
10164	response to cesium ion	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cesium stimulus.
10165	response to X-ray	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of X-ray radiation. An X-ray is a form of electromagnetic radiation with a wavelength in the range of 10 nanometers to 100 picometers (corresponding to frequencies in the range 30 PHz to 3 EHz).
10166	wax metabolic process	P	The chemical reactions and pathways involving wax, a compound containing C16 and C18 fatty acids.
10167	response to nitrate	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrate stimulus.
10168	ER body	C	A novel compartment found in plant cells that is derived from the ER. The structures have a characteristic shape and size (10 mm long and 0.5 mm wide) and are surrounded with ribosomes. They have been found in Arabidopsis thaliana and related Brassicaceae species.
10169	thioglucosidase complex	C	A large (200-800 kDa) multiprotein complex formed by 70-kDa and 5-kDa myrosinases, myrosinase- binding proteins (MBPs), MBP-related proteins and myrosinase-associated proteins. The complex has been identified in Brassica napus seeds.
10170	glucose-1-phosphate adenylyltransferase complex	C	Complex that catalyzes the synthesis of ADP-glucose and pyrophosphate from glucose-1-phosphate and ATP. In plants, the complex is a heterotetramer composed of two types of subunits (small and large). In bacteria, the enzyme complex is composed of four identical subunits.
10171	body morphogenesis	P	The process in which the anatomical structures of the soma are generated and organized.
10172	embryonic body morphogenesis	P	The process in which the anatomical structures of the embryonic soma are generated and organized.
10174	nucleoside transmembrane transporter activity, against a concentration gradient	F	Catalysis of the transfer of a nucleoside, from one side of a membrane to the other, up a concentration gradient.
10175	sphingosine transmembrane transporter activity	F	Enables the transfer of amino alcohol sphingosine from one side of the membrane to the other.
10176	homogentisate phytyltransferase activity	F	Catalysis of the reaction: homogentisate + phytyl diphosphate + H+ = 2-methyl-6-phytyl-1,4-benzoquinone + CO2 + diphosphate. 2-methyl-6-phytyl-1,4-benzoquinone is also known as 2-methyl-6-phytylplastoquinol.
10177	2-(2'-methylthio)ethylmalate synthase activity	F	Catalysis of the reaction: 2-oxo-4-methylthiobutanoate + acetyl-CoA + H2O = 2-(2'-methylthio)ethylmalic-acid + coenzyme A + H+.
10178	IAA-amino acid conjugate hydrolase activity	F	Catalysis of the cleavage of the amide bond between IAA (auxin) and the conjugated amino acid.
10179	IAA-Ala conjugate hydrolase activity	F	Catalysis of the reaction: indole-3-acetyl-alanine + H2O = indole-3-acetate + L-alanine.
10180	thioglucosidase binding	F	Interacting selectively and non-covalently with the enzyme thioglucosidase.
10181	FMN binding	F	Interacting selectively and non-covalently with flavin mono nucleotide. Flavin mono nucleotide (FMN) is the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes.
10182	sugar mediated signaling pathway	P	The process in which a change in the level of a mono- or disaccharide such as glucose, fructose or sucrose triggers the expression of genes controlling metabolic and developmental processes.
10183	pollen tube guidance	P	The process in which the growth of pollen tube is directed towards the female gametophyte.
10184	cytokinin transport	P	The directed movement of cytokinins, a class of adenine-derived compounds that can function in plants as growth regulators, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
10185	regulation of cellular defense response	P	Any process that modulates the frequency, rate or extent of cellular defense response.
10186	positive regulation of cellular defense response	P	Any process that activates or increases the frequency, rate or extent of cellular defense response.
10187	negative regulation of seed germination	P	Any process that stops, prevents, or reduces the frequency, rate or extent of seed germination.
10188	response to microbial phytotoxin	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a microbial phytotoxin stimulus. A microbial phytotoxin is a chemical substance produced by microbes which is toxic to plants.
10189	vitamin E biosynthetic process	P	The chemical reactions and pathways resulting in the formation of vitamin E, tocopherol, which includes a series of eight structurally similar compounds. Alpha-tocopherol is the most active form in humans and is a powerful biological antioxidant.
10190	cytochrome b6f complex assembly	P	Formation of cytochrome b6f complex, a complex that transfers electrons from reduced plastoquinone to oxidized plastocyanin and translocates protons from the stroma to the lumen, by the aggregation, arrangement and bonding together of its constituents.
10191	mucilage metabolic process	P	The chemical reactions and pathways involving mucilage, a gelatinous substance secreted by plants.
10192	mucilage biosynthetic process	P	The chemical reactions and pathways resulting in the formation of mucilage, a gelatinous substance secreted by plants.
10193	response to ozone	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ozone stimulus.
10196	nonphotochemical quenching	P	The process by which excess light energy absorbed by chlorophyll and not used to drive photosynthesis is emitted as heat. This process helps maintain the balance between dissipation and utilization of light energy to minimize generation of oxidizing molecules, thereby protecting the plant against photo-oxidative damage.
10197	polar nucleus fusion	P	The merging of the polar nuclei, the two nuclei contained within the same cell that are created from the mitotic division of the megaspore during angiosperm reproduction. Polar nuclear fusion takes place in the ovule, forming in the fusion nucleus and giving rise to the endosperm when fertilized.
10198	synergid death	P	Synergid cells undergo degeneration and death in response to penetration by the pollen tube. It is an active process that involves a dramatic decrease in cell volume, collapse of the vacuoles, and complete disintegration of the plasma membrane and most organelles.
10199	organ boundary specification between lateral organs and the meristem	P	The process in which boundaries between lateral organs and the meristem is established and maintained.
10200	response to chitin	P	A process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chitin stimulus.
10201	response to continuous far red light stimulus by the high-irradiance response system	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the detection of a continuous far red light stimulus by the high-irradiance response system. Far red light is electromagnetic radiation of wavelength 700-800nm. The activity of the high-irradiance response system is characterized by stronger effects of continuous than pulsed light at equal total fluence.
10202	response to low fluence red light stimulus	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a low fluence red light stimulus. Red light is electromagnetic radiation of wavelength of 580-700nm. Low fluence red light is defined in this case as short pulses of red light followed by darkness, providing a light level of 0.001-0.1 mmol/m2/sec.
10203	response to very low fluence red light stimulus	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a very low fluence red light stimulus. Red light is electromagnetic radiation of wavelength of 580-700nm. Very low fluence red light is defined in this case as short pulses of red light followed by darkness, providing light levels of less than 0.001 mmol/m2/sec.
10204	defense response signaling pathway, resistance gene-independent	P	A series of molecular signals that is activated during defense response and does not depend upon R-genes.
10205	photoinhibition	P	The mechanism by which high light intensity inhibits photosynthesis through inactivation of the D1 protein of photosystem II.
10206	photosystem II repair	P	Proteolysis of the damaged D1 protein and re-assembly of a new D1 subunit in the photosystem II following photoinhibition.
10207	photosystem II assembly	P	The aggregation, arrangement and bonding together of a set of components to form a photosystem II complex on the thylakoid membrane. The photosystem II complex consists of at least 20 polypeptides and around 80 cofactors in most organisms.
10208	pollen wall assembly	P	The formation of reticulate pollen wall pattern consisting of two layers, exine and intine.
10209	vacuolar sorting signal binding	F	Interacting selectively and non-covalently with a vacuolar sorting signal, a specific peptide sequence that acts as a signal to localize the protein within the vacuole.
10210	IAA-Phe conjugate hydrolase activity	F	Catalysis of the reaction: indole-3-acetyl-phenylalanine + H2O = indole-3-acetate + phenylalanine.
10211	IAA-Leu conjugate hydrolase activity	F	Catalysis of the reaction: indole-3-acetyl-leucine + H2O = indole-3-acetate + L-leucine.
10212	response to ionizing radiation	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ionizing radiation stimulus. Ionizing radiation is radiation with sufficient energy to remove electrons from atoms and may arise from spontaneous decay of unstable isotopes, resulting in alpha and beta particles and gamma rays. Ionizing radiation also includes X-rays.
10213	non-photoreactive DNA repair	P	A DNA repair process that is involved in repairing UV-induced DNA damage under non-photoreactivating conditions. The mechanism by which this repair process operates has not yet been completely elucidated.
10214	seed coat development	P	The process whose specific outcome is the progression of the seed coat over time, from its formation to the mature structure.
10215	cellulose microfibril organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cellulose microfibril, any of the cellulose structures laid down in orthogonal layers in a plant cell wall.
10216	maintenance of DNA methylation	P	Any process involved in maintaining the methylation state of a nucleotide sequence.
10217	cellular aluminum ion homeostasis	P	Any process involved in the maintenance of an internal steady state of aluminum ions at the level of a cell.
10218	response to far red light	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of far red light stimulus. Far red light is electromagnetic radiation of wavelength 700-800nm. An example of this response is seen at the beginning of many plant species developmental stages. These include germination, and the point when cotyledon expansion is triggered. In certain species these processes take place in response to absorption of red light by the pigment molecule phytochrome, but the signal can be reversed by exposure to far red light. During the initial phase the phytochrome molecule is only present in the red light absorbing form, but on absorption of red light it changes to a far red light absorbing form, triggering progress through development. An immediate short period of exposure to far red light entirely returns the pigment to its initial state and prevents triggering of the developmental process. A thirty minute break between red and subsequent far red light exposure renders the red light effect irreversible, and development then occurs regardless of whether far red light exposure subsequently occurs.
10219	regulation of vernalization response	P	Any process that modulates the frequency, rate or extent of the vernalization response, by which induction of flowering is normally caused by extended exposure to cold temperatures.
10220	positive regulation of vernalization response	P	Any process that activates or induces the rate of the vernalization response, by which induction of flowering is normally caused by extended exposure to cold temperatures.
10221	negative regulation of vernalization response	P	Any process that stops, prevents or reduces the vernalization response, by which induction of flowering is normally caused by extended exposure to cold temperatures.
10222	stem vascular tissue pattern formation	P	Vascular tissue pattern formation as it occurs in the stem of vascular plants.
10223	secondary shoot formation	P	The process that gives rise to secondary (or auxiliary or axillary) shoots in plants. This process pertains to the initial formation of a structure from unspecified parts. These secondary shoots originate from secondary meristems initiated in the axils of leaf primordia. Axillary meristems function like the shoot apical meristem of the primary shoot initating the development of lateral organs.
10224	response to UV-B	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a UV-B radiation stimulus. UV-B radiation (UV-B light) spans the wavelengths 280 to 315 nm.
10225	response to UV-C	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a UV-C radiation stimulus. UV-C radiation (UV-C light) spans the wavelengths 100 to 280 nm.
10226	response to lithium ion	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lithium (Li+) ion stimulus.
10227	floral organ abscission	P	The controlled shedding of floral organs.
10228	vegetative to reproductive phase transition of meristem	P	The process involved in transforming a meristem that produces vegetative structures, such as leaves, into a meristem that produces reproductive structures, such as a flower or an inflorescence.
10229	inflorescence development	P	The process whose specific outcome is the progression of an inflorescence over time, from its formation to the mature structure.
10230	alternative respiration	P	Alternative respiration pathway consumes oxygen, oxidizes NADH to NAD+ and generates water. During electron flow, proton motive force is diminished resulting in fewer molecules of ATP compared to cytochrome pathway. The pathway is found in plants, algae and some protozoa.
10231	maintenance of seed dormancy	P	Any process that maintains a seed in a dormant state.
10232	vascular transport	P	The directed movement of substances, into, out of or within a cell, either in a vascular tissue or in the vascular membrane.
10233	phloem transport	P	The directed movement of substances, into, out of or within a cell, either in a phloem tissue or in the phloem membrane.
10234	anther wall tapetum cell fate specification	P	The process in which a cell becomes capable of differentiating autonomously into a tapetal cell of anthers in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.
10235	guard mother cell cytokinesis	P	The stereotyped symmetric cell division by which guard mother cell give rise to stomatal guard cells.
10236	plastoquinone biosynthetic process	P	The chemical reactions and pathways resulting in the formation of plastoquinone, a lipid-soluble electron-transporting coenzyme present in the chloroplast.
10238	response to proline	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a proline stimulus.
10239	chloroplast mRNA processing	P	Steps involved in processing precursor RNAs arising from transcription of operons in the chloroplast genome into mature mRNAs.
10240	plastid pyruvate dehydrogenase complex	C	Complex that carries out the oxidative decarboxylation of pyruvate to form acetyl-CoA; comprises subunits possessing three catalytic activities: pyruvate dehydrogenase (E1), dihydrolipoamide S-acetyltransferase (E2), and dihydrolipoamide dehydrogenase (E3). This complex is found in plant plastids and is distinct from the one found in mitochondria.
10241	ent-kaurene oxidation to kaurenoic acid	P	The three successive oxidations of the 4-methyl group of ent-kaurene to form ent-kaur-16-en-19-oate, kaurenoic acid. This process may be carried out entirely by the enzyme ent-kaurene oxidase.
10242	oxygen evolving activity	F	Catalysis of the reaction: 2 H2O = O2 + 4 H+ + 4 e-. The evolution of oxygen from oxidizing water is carried out by the oxygen evolving complex in photosystem II of plants. P680+, the photochemically oxidized reaction-center chlorophyll of PSII, is a strong biological oxidant. The reduction potential of P680+ is more positive than that of water, and thus it can oxidize water to give O2 and H+ ions. The oxygen escapes as a gas while the H+ ions remain in solution inside the thylakoid vesicle.
10243	response to organonitrogen compound	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organonitrogen stimulus. An organonitrogen compound is formally a compound containing at least one carbon-nitrogen bond.
10244	response to low fluence blue light stimulus by blue low-fluence system	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the detection of a low fluence blue light stimulus by the blue low-fluence system. Blue light is electromagnetic radiation with a wavelength of between 440 and 500nm. The blue low-fluence system responds to blue light at or below 0.1 micromols/m2. In certain species excitation of the blue low fluence system induces the transcription of a number of nuclear and plastid coded genes.
10245	radial microtubular system formation	P	Formation of radial microtubular systems during male meiotic cytokinesis in plants.
10246	rhamnogalacturonan I biosynthetic process	P	The chemical reactions and pathways resulting in the formation of rhamnogalacturonan I component of pectin, a rhamnose-rich pectic polysaccharide.
10247	detection of phosphate ion	P	The series of events in which a phosphate ion stimulus is received by a cell and converted into a molecular signal.
10248	establishment or maintenance of transmembrane electrochemical gradient	P	The directed movement of ions to establish or maintain an electrochemical gradient across a membrane by means of some agent such as a transporter or pore.
10249	auxin conjugate metabolic process	P	The chemical reactions and pathways involving auxin conjugates, a bound form of auxin.
10250	S-methylmethionine biosynthetic process	P	The chemical reactions and pathways resulting in the formation of S-methyl-methionine (SMM) from methionine and S-adenosyl-methionine (Ado-Met), catalyzed by methionine S-methyltransferase (MMT). SMM can be reconverted to methionine by donating a methyl group to homocysteine, and concurrent operation of this reaction and that mediated by MMT sets up the SMM cycle.
10252	auxin homeostasis	P	A homeostatic process that maintains an endogenous steady-state concentration of primary auxin, or constant level of auxin in a biological system, by a number of biochemical processes including transport, biosynthesis, catabolism and conjugation.
10253	UDP-rhamnose biosynthetic process	P	The chemical reactions and pathways resulting in the formation of UDP-L-rhamnose, a substance composed of rhamnose in glycosidic linkage with uridine diphosphate.
10254	nectary development	P	The process whose specific outcome is the progression of the floral nectaries over time, from its formation to the mature structure.
10255	glucose mediated signaling pathway	P	The process in which a change in the level of mono- and disaccharide glucose trigger the expression of genes controlling metabolic and developmental processes.
10256	endomembrane system organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the endomembrane system.
10257	NADH dehydrogenase complex assembly	P	The aggregation, arrangement and bonding together of a set of components to form an NADH dehydrogenase complex.
10258	NADH dehydrogenase complex (plastoquinone) assembly	P	The aggregation, arrangement and bonding together of a set of components to form NADH:plastoquinone dehydrogenase complex, which is involved in the non-photochemical reduction of plastoquinones, as well as the cyclic electron transport around photosystem I.
10259	multicellular organism aging	P	An aging process that has as participant a whole multicellular organism. Multicellular organism aging includes loss of functions such as resistance to disease, homeostasis, and fertility, as well as wear and tear. Multicellular organisms aging includes processes like cellular senescence and organ senescence, but is more inclusive. May precede death (GO:0016265) of an organism and may succeed developmental maturation (GO:0021700).
10260	animal organ senescence	P	The process that occurs in an animal organ near the end of its active life that is associated with the dismantling of cell components and membranes, and an overall decline in metabolism.
10262	somatic embryogenesis	P	Initiation of a somatic embryo-an embryo arising from previously differentiated somatic cells, rather than from fused haploid gametes.
10263	tricyclic triterpenoid biosynthetic process	P	The chemical reactions and pathways resulting in the formation of tricyclic triterpenoid compounds, terpenoids with 6 isoprene units and 3 carbon rings.
10264	myo-inositol hexakisphosphate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of phytic acid, myo-inositol hexakisphosphate, a regulator of intracellular signaling, a highly abundant animal anti-nutrient and a phosphate and mineral storage compound in plant seeds.
10265	SCF complex assembly	P	The aggregation, arrangement and bonding together of a set of components to form the SKP1-Cullin/Cdc53-F-box protein ubiquitin ligase (SCF) complex.
10266	response to vitamin B1	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin B1 stimulus.
10267	production of ta-siRNAs involved in RNA interference	P	Cleavage of double-stranded RNA to form trans-acting small interfering RNA molecules (siRNAs) of 21-23 nucleotides. ta-siRNAs arise from PolII genes and function like miRNAs to guide cleavage of target mRNAs.
10268	brassinosteroid homeostasis	P	Any process involved in the maintenance of an internal steady state of brassinosteroids within an organism or cell.
10269	response to selenium ion	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from selenium ion.
10270	photosystem II oxygen evolving complex assembly	P	The aggregation, arrangement and bonding together of a set of components to form the oxygen evolving complex (OEC) of photosystem II on a thylakoid membrane. The OEC protects the calcium-4 manganese-5 oxide cluster which is bound to the D1 and CP43 proteins. The exact protein composition of the OEC varies between cyanobacteria and plants, and in plants consists of three extrinsic nuclear-encoded polypeptides: PsbO, PsbP and PsbQ.
10271	regulation of chlorophyll catabolic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of chlorophyll.
10272	response to silver ion	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a silver ion stimulus.
10273	detoxification of copper ion	P	Any process that reduces or removes the toxicity of copper ion. These include transport of copper away from sensitive areas and to compartments or complexes whose purpose is sequestration of copper ion.
10274	hydrotropism	P	Growth or movement in a sessile organism toward or away from water, as of the roots of a plant.
10275	NAD(P)H dehydrogenase complex assembly	P	The aggregation, arrangement and bonding together of a set of components to form NAD(P)H dehydrogenase complex, which is involved in electron transport from an unidentified electron donor, possibly NAD(P)H or ferredoxin(Fd) to the plastoquinone pool.
10276	phytol kinase activity	F	Catalysis of the reaction: phytol + CTP = phytyl monophosphate + CDP + H+.
10277	chlorophyllide a oxygenase [overall] activity	F	Catalysis of the reactions: chlorophyllide a + O2 + NADPH + H+ = 7-hydroxychlorophyllide a + H2O + NADP+; and 7-hydroxychlorophyllide a + O2 + NADPH + H+ = chlorophyllide b + 2 H2O + NADP+.
10278	chloroplast outer membrane translocon	C	The protein transport machinery of the chloroplast outer membrane that contains at least three components Toc159, Toc75 and Toc34, interacts with precursor proteins which are imported into the chloroplast in a GTP dependant manner.
10279	indole-3-acetic acid amido synthetase activity	F	Catalysis of the reaction: indole-3-acetic acid + an amino acid = an indole-3-acetic acid amide conjugate.
10280	UDP-L-rhamnose synthase activity	F	Catalysis of the reaction: UDP-D-glucose + NADPH + H+ = UDP-L-rhamnose + NADP+ + H2O.
10282	senescence-associated vacuole	C	A lytic vacuole that is maintained at acidic pH and has different tonoplast composition compared to the central vacuole. Found during leaf senescence and develops in the peripheral cytoplasm of cells that contain chloroplast.
10283	pinoresinol reductase activity	F	Catalysis of the reaction: pinoresinol + NADPH + H+ = lariciresinol + NADP+.
10284	lariciresinol reductase activity	F	Catalysis of the reaction: lariciresinol + NADPH + H+ = secoisolariciresinol + NADP+.
10285	L,L-diaminopimelate aminotransferase activity	F	Catalysis of the reaction: 2-oxoglutarate + LL-2,6-diaminopimelate = (S)-2,3,4,5-tetrahydrodipicolinate + L-glutamate + H(2)O + H(+).
10286	heat acclimation	P	Any process that increases heat tolerance of an organism in response to high temperatures.
10287	plastoglobule	C	A lipoprotein particle present in chloroplasts. They are rich in non-polar lipids (triglycerides, esters) as well as in prenylquinones, plastoquinone and tocopherols. Plastoglobules are often associated with thylakoid membranes, suggesting an exchange of lipids with thylakoids.
10288	response to lead ion	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lead ion stimulus.
10289	homogalacturonan biosynthetic process	P	The chemical reactions and pathways resulting in the formation of the pectidic homogalacturonan, characterized by a backbone of (1->4)-linked alpha-D-GalpA residues that can be methyl-esterified at C-6 and carry acetyl groups on O-2 and O-3.
10290	chlorophyll catabolite transmembrane transporter activity	F	Enables the directed movement of chlorophyll catabolites such as non-fluorescent chlorophyll catabolites (NCCs), from one side of the membrane to the other.
10291	carotene beta-ring hydroxylase activity	F	Catalysis of the reaction: a carotene + a reduced electron acceptor + O2 = C3-hydroxylated carotene + an oxidized electron acceptor + H2O. This is a general reaction to represent the C3 hydroxylation of the beta ring of a carotene.
10292	GTP:GDP antiporter activity	F	Catalysis of the reaction: GTP(out) + GDP(in) = GTP(in) + GDP(out).
10293	abscisic aldehyde oxidase activity	F	Catalysis of the reaction: (+)-abscisic aldehyde + H(2)O + O(2) = abscisate + H(2)O(2) + H(+).
10294	abscisic acid glucosyltransferase activity	F	Catalysis of the reaction: (+)-abscisate + UDP-D-glucose = abscisic acid glucose ester + UDP.
10295	(+)-abscisic acid 8'-hydroxylase activity	F	Catalysis of the reaction: (+)-abscisate + H(+) + NADPH + O(2) = (+)-8'-hydroxyabscisate + H(2)O + NADP(+).
10296	prenylcysteine methylesterase activity	F	Catalysis of the reaction: protein C-terminal S-farnesyl-L-cysteine methyl ester + H2O = protein C-terminal S-farnesyl-L-cysteine + methanol + H+.
10297	heteropolysaccharide binding	F	Interacting selectively and non-covalently with heteropolysaccharides. A heteropolysaccharide is a glycan composed of more than one type of monosaccharide residue.
10298	dihydrocamalexic acid decarboxylase activity	F	Catalysis of the reaction: dihydrocamalexic acid = camalexin + CO2 + H+.
10299	detoxification of cobalt ion	P	Any process that reduces or removes the toxicity of cobalt ion. These include transport of cobalt away from sensitive areas and to compartments or complexes whose purpose is sequestration of cobalt ion.
10301	xanthoxin dehydrogenase activity	F	Catalysis of the reaction: NAD(+) + xanthoxin = (+)-abscisic aldehyde + H(+) + NADH.
10303	limit dextrinase activity	F	Catalysis of the hydrolysis of (1,6)-alpha-D-glucosidic linkages in alpha- and beta-limit dextrins of amylopectin and glycogen, and in amylopectin and pullulan.
10304	PSII associated light-harvesting complex II catabolic process	P	The chemical reactions and pathways resulting in the breakdown of one or more components of the light-harvesting complex of photosystem II.
10305	leaf vascular tissue pattern formation	P	Vascular tissue pattern formation as it occurs in the leaf of vascular plants.
10306	rhamnogalacturonan II biosynthetic process	P	The chemical reactions and pathways resulting in the formation of rhamnogalacturonan II, a low molecular mass (5 - 10KDa) pectic polysaccharide, conserved in the primary walls of dicotyledenous and monocotyledenous plants and gymnosperms.
10307	acetylglutamate kinase regulator activity	F	Modulates the enzyme activity of acetylglutamate kinase.
10308	acireductone dioxygenase (Ni2+-requiring) activity	F	Catalysis of the reaction: 1,2-dihydroxy-5-(methylthio)pent-1-en-3-one + O(2) = 3-(methylthio)propanoate + CO + formate.
10309	acireductone dioxygenase [iron(II)-requiring] activity	F	Catalysis of the reaction: 1,2-dihydroxy-5-(methylthio)pent-1-en-3-one + O(2) = 4-methylthio-2-oxobutanoate + formate + H(+).
10310	regulation of hydrogen peroxide metabolic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving hydrogen peroxide.
10311	lateral root formation	P	The process that gives rise to a lateral root. This process pertains to the initial formation of a structure from unspecified parts. A lateral root primordium represents an organized group of cells derived from the root pericycle that will differentiate into a new root, as opposed to the initiation of the main root from the embryo proper.
10312	detoxification of zinc ion	P	Any process that reduces or removes the toxicity of zinc ion. These include transport of zinc away from sensitive areas and to compartments or complexes whose purpose is sequestration of zinc ion.
10313	phytochrome binding	F	Interacting selectively and non-covalently with phytochrome.
10314	phosphatidylinositol-5-phosphate binding	F	Interacting selectively and non-covalently with phosphatidylinositol-5-phosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 5' position.
10315	auxin efflux	P	The process involved in the transport of auxin out of the cell.
10316	pyrophosphate-dependent phosphofructokinase complex	C	Heterodimeric complex that catalyzes the pyrophosphate-dependent phosphorylation of D-fructose 6-phosphate into D-fructose 1,6-bisphosphate.
10317	pyrophosphate-dependent phosphofructokinase complex, alpha-subunit complex	C	Refers to the alpha subunit of the heterodimeric complex that possesses pyrophosphate-dependent phosphofructokinase activity.
10318	pyrophosphate-dependent phosphofructokinase complex, beta-subunit complex	C	Refers to the beta subunit of the heterodimeric complex that possesses pyrophosphate-dependent phosphofructokinase activity.
10319	stromule	C	Thin filamentous structure extending from the surface of all plastid types examined so far, including chloroplast, proplastid, etioplast, leucoplast, amyloplast, and chromoplast. In general, stromules are more abundant in tissues containing non-green plastids, and in cells containing smaller plastids. The primary function of stromules is still unresolved, although the presence of stromules markedly increases the plastid surface area, potentially increasing transport to and from the cytosol. Other functions of stromules, such as transfer of macromolecules between plastids and starch granule formation in cereal endosperm, may be restricted to particular tissues and cell types.
10321	regulation of vegetative phase change	P	Any process that modulates the frequency, rate or extent of vegetative phase change. Vegetative phase change is the set of post-embryonic processes involved in the transition of a plant from a juvenile phase of vegetative development to an adult phase of vegetative development.
10322	regulation of isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of isopentenyl diphosphate produced via the methylerythritol (MEP) pathway (mevalonate-independent).
10323	negative regulation of isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of isopentenyl diphosphate produced via the methylerythritol (MEP) pathway (mevalonate-independent).
10324	membrane invagination	P	The infolding of a membrane.
10325	raffinose family oligosaccharide biosynthetic process	P	The chemical reactions and pathways resulting in the formation of raffinose family oligosaccharides (RFOs, such as raffinose, stachyose, verbascose and other molecules with a higher degree of galactosyl polymerization).
10326	methionine-oxo-acid transaminase activity	F	Catalysis of the reaction: methionine + a 2-oxo acid = 2-oxo-4-methylthiobutanoate + an amino acid.
10327	acetyl CoA:(Z)-3-hexen-1-ol acetyltransferase activity	F	Catalysis of the reaction: acetyl-CoA + (Z)-3-hexen-1-ol = CoA + (Z)-3-hexen-1-yl acetate.
10328	auxin influx transmembrane transporter activity	F	Catalysis of the transfer of auxin, from one side of a membrane to the other, into a cell.
10329	auxin efflux transmembrane transporter activity	F	Catalysis of the transfer of auxin, from one side of a membrane to the other, out of a cell.
10330	cellulose synthase complex	C	A large, multimeric protein complex, organized in a rosette, which catalyzes the biosynthesis of cellulose for the plant cell wall.
10331	gibberellin binding	F	Interacting selectively and non-covalently with gibberellins, plant hormones that regulate aspects of plant growth.
10332	response to gamma radiation	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gamma radiation stimulus. Gamma radiation is a form of electromagnetic radiation (EMR) or light emission of a specific frequency produced from sub-atomic particle interaction, such as electron-positron annihilation and radioactive decay. Gamma rays are generally characterized as EMR having the highest frequency and energy, and also the shortest wavelength, within the electromagnetic radiation spectrum.
10333	terpene synthase activity	F	Catalysis of the formation of cyclic terpenes through the cyclization of linear terpenes (e.g. isopentenyl-PP, geranyl-PP, farnesyl-PP and geranylgeranyl-PP) containing varying numbers of isoprene units.
10334	sesquiterpene synthase activity	F	Catalysis of the reaction: trans,trans-farnesyl diphosphate = a sesquiterpene + diphosphate. Sesquiterpenes are terpenes containing three isoprene units, i.e. 15 carbons.
10335	response to non-ionic osmotic stress	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of non-ionic solutes (e.g. mannitol, sorbitol) in the environment.
10336	gibberellic acid homeostasis	P	Any biological process involved in the maintenance of an internal steady state of gibberellic acid; may involve transport, biosynthesis, catabolism or conjugation.
10337	regulation of salicylic acid metabolic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving salicylic acid.
10338	leaf formation	P	The process that gives rise to a leaf. This process pertains to the initial formation of a structure from unspecified parts.
10339	external side of cell wall	C	The side of the cell wall that is opposite to the side that faces the cell and its contents.
10340	carboxyl-O-methyltransferase activity	F	Catalysis of the transfer of a methyl group to the carboxyl group of an acceptor molecule to form a methyl ester.
10341	gibberellin carboxyl-O-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + a gibberellin = S-adenosyl-L-homocysteine + a gibberellin methyl ester.
10342	endosperm cellularization	P	The separation of the multi-nucleate endosperm into individual cells. In many plant species, the endosperm that nurtures the embryo in the seed initially develops as a syncytium. This syncytial phase ends with simultaneous partitioning of the multi-nucleate cytoplasm into individual cells, a process referred to as cellularization.
10343	singlet oxygen-mediated programmed cell death	P	Programmed cell death induced by singlet oxygen. Programmed cell death is the cell death resulting from activation of endogenous cellular processes.
10344	seed oilbody biogenesis	P	A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a seed oilbody. Seed oilbodies are simple organelles comprising a matrix of triglyceride surrounded by a phospholipid monolayer embedded and covered with unique proteins called oleosins. Seed oilbodies supply the energy requirements for the growth of the seedling after germination.
10345	suberin biosynthetic process	P	The chemical reactions and pathways resulting in the formation of suberin monomers and suberin polyesters. Suberin monomers are derived from fatty acids and trans-cinnamic acids. The monomers are then cross-linked with glycerols.
10346	shoot axis formation	P	The process that gives rise to a shoot axis. This process pertains to the initial formation of a structure from unspecified parts.
10347	L-galactose-1-phosphate phosphatase activity	F	Catalysis of the reaction: L-galactose-1-phosphate + H2O = L-galactose + phosphate.
10348	lithium:proton antiporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Li+(in) + H+(out) = Li+(out) + H+(in).
10349	L-galactose dehydrogenase activity	F	Catalysis of the reaction: L-galactose + NAD+ = L-galactono-1,4-lactone + NADH + H+.
10350	cellular response to magnesium starvation	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of magnesium.
10351	lithium ion transport	P	The directed movement of lithium ion into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
10352	lithium ion export	P	The directed movement of lithium ion out of a cell or organelle.
10353	response to trehalose	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a trehalose stimulus.
10354	homogentisate prenyltransferase activity	F	Catalysis of the transfer of a prenyl group from one compound (donor) to homogentisic acid.
10355	homogentisate farnesyltransferase activity	F	Catalysis of the reaction: homogentisic acid + farnesyl diphosphate = 2-methyl-6-farnesylplastoquinol.
10356	homogentisate geranylgeranyltransferase activity	F	Catalysis of the reaction: homogentisic acid + geranylgeranyl diphosphate = 2-methyl-6-geranylgeranylplastoquinol.
10357	homogentisate solanesyltransferase activity	F	Catalysis of the reaction: homogentisic acid + all-trans-nonaprenyl diphosphate + 3 H+ = 2-methyl-6-solanyl-1,4-benzoquinonone + CO2 + diphosphate. 2-methyl-6-solanyl-1,4-benzoquinonone is also known as 2-methyl-6-solanesylplastoquinol and all-trans-nonaprenyl diphosphate as solanesyl diphosphate.
10358	leaf shaping	P	The developmental process that pertains to the organization of a leaf in three-dimensional space once the structure has initially formed.
10359	regulation of anion channel activity	P	Any process that modulates the frequency, rate or extent of anion channel activity.
10360	negative regulation of anion channel activity	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of the anion channel activity.
10361	regulation of anion channel activity by blue light	P	Any process in which blue light modulates the frequency, rate or extent of anion channel activity.
10362	negative regulation of anion channel activity by blue light	P	Any process in which blue light stops, prevents, or reduces the frequency, rate, or extent of the anion channel activity.
10363	regulation of plant-type hypersensitive response	P	Any endogenous process that modulates the frequency, rate or extent of the plant hypersensitive response.
10364	regulation of ethylene biosynthetic process	P	Any process that modulates the frequency, rate, or extent of an ethylene biosynthetic process.
10365	positive regulation of ethylene biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of an ethylene biosynthetic process.
10366	negative regulation of ethylene biosynthetic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of an ethylene biosynthetic process.
10367	extracellular isoamylase complex	C	A protein complex whose composition varies amongst species; in rice it probably exists in a homo-tetramer to homo-hexamer form and in Gram negative bacteria as a dimer. Functions in the hydrolysis of alpha-(1,6)-D-glucosidic branch linkages. Isoamylases in animals are localized in the extracellular space.
10368	chloroplast isoamylase complex	C	A protein complex whose composition varies amongst species; in rice it probably exists in a homo-tetramer to homo-hexamer form and in Gram negative bacteria as a dimer. Functions in the hydrolysis of alpha-(1,6)-D-glucosidic branch linkages. Isoamylases in plants are intracellular and probably chloroplast localized.
10369	chromocenter	C	A region in which centric, heterochromatic portions of one or more chromosomes form a compact structure.
10370	perinucleolar chromocenter	C	A chromocenter adjacent to the nucleolus.
10371	regulation of gibberellin biosynthetic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of gibberellins.
10372	positive regulation of gibberellin biosynthetic process	P	Any process that activates, maintains or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of gibberellins.
10373	negative regulation of gibberellin biosynthetic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of gibberellins.
10374	stomatal complex development	P	The process whose specific outcome is the progression of the stomatal complex over time from its formation to the mature structure. The stomatal complex is the stomatal guard cells and their associated epidermal cells.
10375	stomatal complex patterning	P	The regionalization process of establishing the non-random spatial arrangement of stomatal complex on the surface of a leaf. The stomatal complex is the stomatal guard cells and their associated epidermal cells.
10376	stomatal complex formation	P	The process that gives rise to the stomatal complex. This process pertains to the initial formation of a structure from unspecified parts. The stomatal complex is the stomatal guard cells and their associated epidermal cells.
10377	guard cell fate commitment	P	The process in which the developmental fate of a cell becomes restricted such that it will develop into a stomatal guard cell. Guard cells are located in the leaf epidermis and pairwise surround stomatal pores, which allow CO2 influx for photosynthetic carbon fixation and water loss via transpiration to the atmosphere.
10378	temperature compensation of the circadian clock	P	The process in which the circadian clock maintains robust and accurate timing over a broad range of physiological temperatures. The circadian clock is an endogenous 24-h timer found in most eukaryotes and in photosynthetic bacteria. The clock drives rhythms in the physiology, biochemistry, and metabolism of the organisms.
10379	phaseic acid biosynthetic process	P	The chemical reactions and pathways resulting in the formation of phaseic acid (PA), a catabolite of the plant hormone abscisic acid (ABA).
10380	regulation of chlorophyll biosynthetic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of chlorophyll, any compound of magnesium complexed in a porphyrin (tetrapyrrole) ring and which functions as a photosynthetic pigment, from less complex precursors.
10381	attachment of peroxisome to chloroplast	P	The process in which a peroxisome is transported to, and/or maintained in, a location adjacent to the chloroplast.
10383	cell wall polysaccharide metabolic process	P	The chemical reactions and pathways involving cell wall polysaccharides.
10384	cell wall proteoglycan metabolic process	P	The chemical reactions and pathways involving cell wall peptidoglycan, a group of glycoproteins that consist of a core-protein backbone O-glycosylated by one or more complex carbohydrates.
10385	double-stranded methylated DNA binding	F	Interacting selectively and non-covalently with double-stranded methylated DNA. Methylation of cytosine or adenine in DNA is an important mechanism for establishing stable heritable epigenetic marks.
10387	COP9 signalosome assembly	P	The aggregation, arrangement and bonding together of a set of components to form a COP9 signalosome.
10388	cullin deneddylation	P	The modification of cullins by removal of ubiquitin-like protein NEDD8 (RUB1).
10389	regulation of G2/M transition of mitotic cell cycle	P	Any process that modulates the rate or extent of progression from G2 phase to M phase of the mitotic cell cycle.
10390	histone monoubiquitination	P	The modification of histones by addition of a single ubiquitin group.
10391	glucomannan metabolic process	P	The chemical reactions and pathways involving glucomannan, a polysaccharide composed of D-glucose and D-mannose. The mannose units form the backbone structure (a linear main chain) with the D-glucose as single side-units.
10392	galactoglucomannan metabolic process	P	The chemical reactions and pathways involving galactoglucomannan, a polysaccharide composed of D-glucose, D-galactose and D-mannose. The mannose units form the backbone structure (a linear main chain) decorated with a mixture of D-glucose and D-galactose side-units.
10393	galacturonan metabolic process	P	The chemical reactions and pathways involving galacturonan, a pectin polymer containing a backbone of alpha-(1->4)-linked D-galacturonic acid residues.
10394	homogalacturonan metabolic process	P	The chemical reactions and pathways involving homogalacturonan, a pectin characterized by a backbone of alpha-(1->4)-linked D-galacturonic acid residues that can be methyl-esterified at C-6 and carry acetyl groups on O-2 and O-3.
10395	rhamnogalacturonan I metabolic process	P	The chemical reactions and pathways involving rhamnogalacturonan I (RGI), a branched pectin with a backbone of alternating alpha-(1->2)-linked rhamnose and alpha-(1->4)-linked D-galacturonic acid residues that carries neutral side-chains of predominantly beta-(1->4)-D-galactose and/or alpha-(1->5)-L-arabinose residues attached to the rhamnose residues of the RGI backbone.
10396	rhamnogalacturonan II metabolic process	P	The chemical reactions and pathways involving rhamnogalacturonan II, a low molecular mass (5-10KDa) pectic polysaccharide. The backbone of RG-II contains at least 8 1,4-linked alpha-D-GalpA residues.
10397	apiogalacturonan metabolic process	P	The chemical reactions and pathways involving the pectic apiogalacturonan, characterized by a backbone of alpha-(1->4)-linked D-galacturonic acid residues substituted with apiose and apiobiose (D-apiofuranosyl-beta-(1->3)-D-apiose) side chains via O-2 or O-3 links.
10398	xylogalacturonan metabolic process	P	The chemical reactions and pathways involving xylogalacturonan, a pectin characterized by a backbone of alpha-(1->4)-linked D-galacturonic acid residues substituted on C-3 with beta-D-xylopyranose residues.
10399	rhamnogalacturonan I backbone metabolic process	P	The chemical reactions and pathways involving the alternating alpha-(1->2)-linked rhamnose and alpha-(1->2)-linked B-galacturonic acid residues of the rhamnogalacturonan I backbone.
10400	rhamnogalacturonan I side chain metabolic process	P	The chemical reactions and pathways involving the side chains of the pectin, rhamnogalacturonan I.
10401	pectic galactan metabolic process	P	The chemical reactions and pathways involving galactan, a polymer of D-galactosyl units that can be found as a side chain of the pectin rhamnogalacturonan I.
10402	pectic arabinan metabolic process	P	The chemical reactions and pathways involving pectic arabinan, a polymer with an alpha-(1->5)-linked L-arabinofuranose (Araf) backbone that can be substituted with Araf-alpha-(1->2)-, Araf-alpha-(1->3)-, and/or Araf-alpha-(1->3)-Araf-alpha-(1->3)-side chains. Arabinan can be found as a side chain of the pectin rhamnogalacturonan I.
10403	pectic arabinogalactan I metabolic process	P	The chemical reactions and pathways involving pectic arabinogalactan I, an alpha-(1,4)-linked D-galactopyranose backbone that is substituted with alpha-l-Araf residues via the O-3 of the D-galactose residues. Arabinogalactan I can be found as a side chain of rhamnogalacturonan I.
10404	cell wall hydroxyproline-rich glycoprotein metabolic process	P	The chemical reactions and pathways involving a cell wall hydroxyproline-rich glycoprotein that consist of a core-protein backbone O-glycosylated by one or more complex carbohydrates.
10405	arabinogalactan protein metabolic process	P	The chemical reactions and pathways involving a cell wall arabinogalactan II glycoprotein, which is composed of a group of core protein of highly varying length and domain complexity. These are O-glycosylated at one or more hydroxyproline residues by arabinogalactan (AG) type II groups, which consist of (1->3)-beta-galactan and (1->6)-beta-linked galactan chains connected to each other by (1->3,1->6)-linked branch points, O-3 and O-6 positions substituted with terminal arabinosyl residues. Also, rhamnose, fucose, glucuronic and galacturonic acid can be present in the glycan structures.
10406	classical arabinogalactan protein metabolic process	P	The chemical reactions and pathways involving a cell wall arabinogalactan II glycoprotein, which is composed of a group of core protein containing Hyp, Ala, Ser, Thr and Gly as the major amino acid constituents, and the C-terminus is GPI anchored.
10407	non-classical arabinogalactan protein metabolic process	P	The chemical reactions and pathways involving a cell wall arabinogalactan II glycoprotein where other amino acids besides Hyp, Ala, Ser, Thr and Gly can be present and grouped into regions, such as a Cys-rich or Asn-rich domains.
10408	fasciclin-like arabinogalactan protein metabolic process	P	The chemical reactions and pathways involving the cell wall arabinogalactan II glycoprotein variant which contains both an arabinogalactan protein (AGP) motif and a fasciclin domain.
10409	extensin metabolic process	P	The chemical reactions and pathways involving extensins, a group of 60-90 kDNA hydroxyproline (Hyp)-rich glycoproteins whose polypeptide backbone consists of many repeats of structural Ser(Hyp)4-6 motifs, with heavily glycosylated 1-4 arabinose residues O-linked to contiguous stretches of Hyp residues, with most of the Ser residues being O-galactosylated.
10410	hemicellulose metabolic process	P	The chemical reactions and pathways involving hemicelluloses, plant cell wall polysaccharides that have a backbone of 1,4-linked beta-D-pyranosyl residues in which O4 is in the equatorial orientation. Many different hemicelluloses usually occur intermixed with each molecular type representing different degrees of polymerization and contain many different sugar monomers, which can include glucose, xylose, mannose, galactose, and arabinose. Hemicelluloses also contain most of the D-pentose sugars and occasionally small amounts of L-sugars as well. Xylose is always the sugar monomer present in the largest amount, but mannuronic acid and galacturonic acid also tend to be present.
10411	xyloglucan metabolic process	P	The chemical reactions and pathways involving xyloglucan, the cross-linking glycan composed of (1->4)-beta-D-glucan backbone substituted at regular intervals with beta-D-xylosyl-(1->6) residues, which is present in the primary cell wall of most higher plants.
10412	mannan metabolic process	P	The chemical reactions and pathways involving mannan, a group of polysaccharides containing a backbone composed of a polymer of D-mannose units.
10413	glucuronoxylan metabolic process	P	The chemical reactions and pathways involving xylan, a polymer containing a beta-(1->4)-linked D-xylose backbone decorated with glucuronic acid side units.
10414	glucuronoarabinoxylan metabolic process	P	The chemical reactions and pathways involving xylan, a polymer containing a beta-(1->4)-linked D-xylose backbone decorated with glucuronic acid and arabinose side units.
10415	unsubstituted mannan metabolic process	P	The chemical reactions and pathways involving the mannan backbone, the unsubstituted polymer of D-mannose units.
10416	arabinoxylan-containing compound metabolic process	P	The chemical reactions and pathways involving an arabinoxylan, a polymer containing a beta-1,4-linked D-xylose backbone decorated with arabinose side units.
10417	glucuronoxylan biosynthetic process	P	The chemical reactions and pathways resulting in the formation of glucuronoxylan, a polymer containing a beta-1,4-linked D-xylose backbone substituted with glucuronic acid residues.
10418	rhamnogalacturonan II backbone metabolic process	P	The chemical reactions and pathways involving the backbone structure of pectic rhamnogalacturonan II. The back bone contains at least 8 1,4-linked alpha-D-GalpA residues.
10419	rhamnogalacturonan II side chain metabolic process	P	The chemical reactions and pathways involving the side chains of pectic rhamnogalacturonan II. A number of structurally distinct di- and oligosaccharides can be attached to the C-3 and C-2 of the backbone, respectively.
10420	polyprenyldihydroxybenzoate methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + 3-polyprenyl-4,5-dihydroxybenzoate = S-adenosyl-L-homocysteine + 3-polyprenyl-4-hydroxy-5-methoxybenzoate + H+.
10421	hydrogen peroxide-mediated programmed cell death	P	Programmed cell death induced by hydrogen peroxide. Programmed cell death is the cell death resulting from activation of endogenous cellular processes.
10422	regulation of brassinosteroid biosynthetic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of brassinosteroids.
10423	negative regulation of brassinosteroid biosynthetic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of brassinosteroids.
10424	DNA methylation on cytosine within a CG sequence	P	The covalent transfer of a methyl group to C-5 or N-4 of a cytosine located within a CG sequence in a DNA molecule.
10425	DNA methylation on cytosine within a CNG sequence	P	The covalent transfer of a methyl group, to C-5 or N-4, of a cytosine located within a CNG sequence in a DNA molecule. N stands for any nucleotide.
10426	DNA methylation on cytosine within a CHH sequence	P	The covalent transfer of a methyl group, to C-5 or N-4, of a cytosine located within an asymmetric CHH sequence in a DNA molecule. H stands for an adenine, cytosine, or thymine nucleotide.
10427	abscisic acid binding	F	Interacting selectively and non-covalently with abscisic acid, plant hormones that regulate aspects of plant growth.
10428	methyl-CpNpG binding	F	Interacting selectively and non-covalently with a methylated cytosine/unspecified/guanine trinucleotide.
10429	methyl-CpNpN binding	F	Interacting selectively and non-covalently with a methylated cytosine/unspecified/unspecified trinucleotide.
10430	fatty acid omega-oxidation	P	A fatty acid oxidation process in which the methyl group at the end of the fatty acid molecule (the omega carbon) is first oxidized to a hydroxyl group, then to an oxo group, and finally to a carboxyl group. The long chain dicarboxylates derived from omega-oxidation then enter the beta-oxidation pathway for further degradation.
10431	seed maturation	P	A process in seed development that occurs after embryogenesis by which a quiescent state is established in a seed. Seed maturation is characterized by storage compound accumulation, acquisition of desiccation tolerance, growth arrest and the entry into a dormancy period of variable length that is broken upon germination.
10432	bract development	P	The process whose specific outcome is the progression of the bract over time, from its formation to the mature structure. A bract is a leaf, usually different in form from the foliage leaves, subtending a flower or inflorescence.
10433	bract morphogenesis	P	The process in which the anatomical structure of a bract are generated and organized. A bract is a leaf, usually different in form from the foliage leaves, subtending a flower or inflorescence.
10434	bract formation	P	The process that gives rise to a bract. This process pertains to the initial formation of a structure from unspecified parts. A bract is a leaf, usually different in form from the foliage leaves, subtending a flower or inflorescence.
10435	3-oxo-2-(2'-pentenyl)cyclopentane-1-octanoic acid CoA ligase activity	F	Catalysis of the reaction: ATP + 3-oxo-2-(2'-pentenyl)-cyclopentane-1-octanoic acid + coenzyme A = AMP + diphosphate + 3-oxo-2-(2'-pentenyl)-cyclopentane-1-octanoyl-CoA + H+. 3-oxo-2-(2'-pentenyl)-cyclopentane-1-octanoic acid is also known as OPC-8:0.
10436	carotenoid dioxygenase activity	F	Catalysis of the oxidative cleavage of carotenoids.
10437	9,10 (9', 10')-carotenoid-cleaving dioxygenase activity	F	Catalysis of the oxidative cleavage of carotenoids at the (9, 10) and/or (9', 10') double bond.
10438	cellular response to sulfur starvation	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of sulfur.
10439	regulation of glucosinolate biosynthetic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glucosinolates, substituted thioglucosides found in rapeseed products and related cruciferae.
10440	stomatal lineage progression	P	The process in which an unspecialized epidermal cell progresses through a series of divisions that culminate in the production of a stomatal complex.
10441	guard cell development	P	The process whose specific outcome is the progression of the guard cell over time, from its formation to the mature structure.
10442	guard cell morphogenesis	P	Generation and organization of the polarized cell that is capable of turgor driven movement.
10443	meristemoid mother cell division	P	The asymmetric cell division by which a meristemoid mother cells (MMC) give rise to a meristemoid and another cell. The other cell may itself become a MMC or may generate an epidermal cell. Any cell that undergoes this type of division is a MMC.
10444	guard mother cell differentiation	P	The process in which a meristemoid acquires the specialized features of a guard mother cell.
10445	nuclear dicing body	C	A small round nuclear body, measuring 0.2-0.8 microns in diameter that is diffusely distributed throughout the nucleoplasm. Several proteins known to be involved in miRNA processing have been localized to these structures. D-bodies are thought to be involved in primary-miRNA processing and/or storage/assembly of miRNA processing complexes.
10446	response to alkaline pH	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus with pH > 7. pH is a measure of the acidity or basicity of an aqueous solution.
10447	response to acidic pH	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus with pH < 7. pH is a measure of the acidity or basicity of an aqueous solution.
10448	vegetative meristem growth	P	The increase in size or mass of a vegetative meristem, a population of undifferentiated cells in a plant shoot which maintains a continuous balance between the production of stem cells and the incorporation of their derivatives into lateral organ primordia.
10449	root meristem growth	P	The increase in size or mass of a root meristem, a population of undifferentiated cells in a plant root which maintains a continuous balance between the production of stem cells and the incorporation of their derivatives into the growth of the root.
10450	inflorescence meristem growth	P	The increase in size or mass of an inflorescence meristem, a population of undifferentiated cells in a plant shoot which produces small leaves and then floral meristems, which will give rise to flowers.
10451	floral meristem growth	P	The increase in size or mass of a floral meristem, a population of undifferentiated cells in a plant that gives rise to a flower.
10452	histone H3-K36 methylation	P	The modification of histone H3 by addition of one or more methyl groups to lysine at position 36 of the histone.
10453	regulation of cell fate commitment	P	Any process that modulates the frequency, rate or extent of cell fate commitment. Cell fate commitment is the commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field.
10454	negative regulation of cell fate commitment	P	Any process that stops, prevents or reduces the frequency or rate of cell fate commitment. Cell fate commitment is the commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field.
10455	positive regulation of cell fate commitment	P	Any process that activates, maintains or increases the frequency or rate of cell fate commitment. Cell fate commitment is the commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field.
10456	cell proliferation in dorsal spinal cord	P	The multiplication or reproduction of cells, resulting in the expansion of the dorsal spinal cord cell population.
10457	centriole-centriole cohesion	P	The process in which the two centrioles within a centrosome remain tightly paired.
10458	exit from mitosis	P	The cell cycle transition where a cell leaves M phase and enters a new G1 phase. M phase is the part of the mitotic cell cycle during which mitosis and cytokinesis take place.
10459	negative regulation of heart rate	P	Any process that stops, prevents or reduces the frequency or rate of heart contraction.
10460	positive regulation of heart rate	P	Any process that activates or increases the frequency or rate of heart contraction.
10461	light-activated ion channel activity	F	Enables the transmembrane transfer of an ion by a channel that opens in response to a light stimulus.
10462	regulation of light-activated voltage-gated calcium channel activity	P	Any process that modulates the frequency, rate or extent of light-activated voltage-gated calcium channel activity.
10463	mesenchymal cell proliferation	P	The multiplication or reproduction of cells, resulting in the expansion of a mesenchymal cell population. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets.
10464	regulation of mesenchymal cell proliferation	P	Any process that modulates the frequency, rate or extent of mesenchymal cell proliferation. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets.
10465	nerve growth factor receptor activity	F	Combining with nerve growth factor (NGF), to prevent apoptosis in neurons and promote nerve growth, or to initiate a change in cell activity.
10466	negative regulation of peptidase activity	P	Any process that stops or reduces the rate of peptidase activity, the hydrolysis of peptide bonds within proteins.
10467	gene expression	P	The process in which a gene's sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
10468	regulation of gene expression	P	Any process that modulates the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
10469	regulation of receptor activity	P	Any process that modulates the frequency, rate or extent of receptor activity. Receptor activity is when a molecule combines with an extracellular or intracellular messenger to initiate a change in cell activity.
10470	regulation of gastrulation	P	Any process that modulates the rate or extent of gastrulation. Gastrulation is the complex and coordinated series of cellular movements that occurs at the end of cleavage during embryonic development of most animals.
10471	GDP-galactose:mannose-1-phosphate guanylyltransferase activity	F	Catalysis of the reaction: GDP-L-galactose + alpha-D-mannose 1-phosphate = GDP-alpha-D-mannose + alpha-L-galactose-1-phosphate.
10472	GDP-galactose:glucose-1-phosphate guanylyltransferase activity	F	Catalysis of the reaction: GDP-L-galactose + alpha-D-glucose 1-phosphate = alpha-L-galactose-1-phosphate + GDP-alpha-D-glucose.
10473	GDP-galactose:myoinositol-1-phosphate guanylyltransferase activity	F	Catalysis of the reaction: GDP-L-galactose + myo-inositol 1-phosphate = alpha-L-galactose-1-phosphate + GDP-myoinositol.
10474	glucose-1-phosphate guanylyltransferase (GDP) activity	F	Catalysis of the reaction: GDP + D-glucose 1-phosphate = phosphate + GDP-glucose.
10475	galactose-1-phosphate guanylyltransferase (GDP) activity	F	Catalysis of the reaction: GDP + L-galactose 1-phosphate = phosphate + GDP-galactose.
10476	gibberellin mediated signaling pathway	P	The series of molecular signals generated as a consequence of gibberellin stimulus.
10477	response to sulfur dioxide	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sulfur dioxide (SO2) stimulus.
10478	chlororespiration	P	A respiratory electron flow (from NAD(P)H to plastoquinone (PQ) and O2) involving both a nonphotochemical reduction and re-oxidation of PQ pool.
10479	stele development	P	The process whose specific outcome is the progression of the stele over time, from its formation to the mature structure. The stele is the central column of primary vascular tissue in the root and any tissue that it surrounds.
10480	microsporocyte differentiation	P	The process aimed at the progression of a microsporocyte cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. A microsporocyte is a diploid (2n) cell that undergoes meiosis and forms four haploid (1n) microspores; also called microspore mother cell and, in seed plants, pollen mother cell.
10481	epidermal cell division	P	Any process resulting in the physical partitioning and separation of an epidermal cell, any of the cells making up the epidermis, into daughter cells.
10482	regulation of epidermal cell division	P	Any process that modulates the frequency, rate or extent of the physical partitioning and separation of an epidermal cell into daughter cells. An epidermal cell is any of the cells that make up the epidermis.
10483	pollen tube reception	P	Interaction between the pollen tube, part of the male gametophyte, and the ovule, part of the female gametophyte, that results in the arrest of pollen tube growth, rupture of the pollen tube and the release of the sperm cells.
10484	H3 histone acetyltransferase activity	F	Catalysis of the reaction: acetyl-CoA + histone H3 = CoA + acetyl-histone H3.
10485	H4 histone acetyltransferase activity	F	Catalysis of the reaction: acetyl-CoA + histone H4 = CoA + acetyl-histone H4.
10486	manganese:proton antiporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Mn2+(in) + H+(out) = Mn2+(out) + H+(in).
10487	thermospermine synthase activity	F	Catalysis of the reaction: S-adenosyl-L-methioninamine + spermidine = S-methyl-5'-thioadenosine + thermospermine + H+.
10488	UDP-galactose:N-glycan beta-1,3-galactosyltransferase activity	F	Catalysis of the reaction: UDP-galactose + N-glycan = galactose-beta-1,3-N-glycan + UDP.
10489	UDP-4-keto-6-deoxy-glucose-3,5-epimerase activity	F	Catalysis of the reaction: UDP-4-keto-6-deoxyglucose = UDP-4-keto-rhamnose.
10490	UDP-4-keto-rhamnose-4-keto-reductase activity	F	Catalysis of the reaction: UDP-4-keto-rhamnose + NADPH = UDP-rhamnose + NADP+.
10491	UTP:arabinose-1-phosphate uridylyltransferase activity	F	Catalysis of the reaction: alpha-L-arabinose 1-phosphate + UTP = UDP-L-arabinose + diphosphate.
10492	maintenance of shoot apical meristem identity	P	The process in which an organism retains a population of shoot apical meristem cells, preventing the commitment of all stem cell progeny to a differentiated cell fate.
10493	Lewis a epitope biosynthetic process	P	The chemical reactions and pathways resulting in the formation of a Lewis a epitope, a trisaccharide (Fuc-alpha-(1->4)[Gal-beta-(1->3)]GlcNAc) characteristic of plant protein N-linked oligosaccharides.
10494	cytoplasmic stress granule	C	A dense aggregation in the cytosol composed of proteins and RNAs that appear when the cell is under stress.
10495	long-distance posttranscriptional gene silencing	P	A posttranscriptional gene silencing process in which the silencing signal originates in a tissue separate from the tissue in which the silencing takes place.
10496	intercellular transport	P	The movement of substances between cells.
10497	plasmodesmata-mediated intercellular transport	P	The movement of substances between cells via plasmodesmata. Plasmodesmata is a fine cytoplasmic channel, found in all higher plants, that connects the cytoplasm of one cell to that of an adjacent cell.
10498	proteasomal protein catabolic process	P	The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds that is mediated by the proteasome.
10499	proteasomal ubiquitin-independent protein catabolic process	P	The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds that is mediated by the proteasome but do not involve ubiquitin.
10500	transmitting tissue development	P	The process whose specific outcome is the progression of the transmitting tract over time, from its formation to the mature structure. The transmitting tissue is the tissue in the style of a carpel through which the pollen tube grows; it connects the stigma and the inside of ovary.
10501	RNA secondary structure unwinding	P	The process in which a secondary structure of RNA are broken or 'melted'.
10506	regulation of autophagy	P	Any process that modulates the frequency, rate or extent of autophagy. Autophagy is the process in which cells digest parts of their own cytoplasm.
10507	negative regulation of autophagy	P	Any process that stops, prevents, or reduces the frequency, rate or extent of autophagy. Autophagy is the process in which cells digest parts of their own cytoplasm.
10508	positive regulation of autophagy	P	Any process that activates, maintains or increases the rate of autophagy. Autophagy is the process in which cells digest parts of their own cytoplasm.
10509	polyamine homeostasis	P	Any biological process involved in the maintenance of an internal steady state of a polyamine.
10510	regulation of acetyl-CoA biosynthetic process from pyruvate	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of acetyl-CoA from pyruvate.
10511	regulation of phosphatidylinositol biosynthetic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of phosphatidylinositol.
10512	negative regulation of phosphatidylinositol biosynthetic process	P	Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of phosphatidylinositol.
10513	positive regulation of phosphatidylinositol biosynthetic process	P	Any process that increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of phosphatidylinositol.
10514	induction of conjugation with cellular fusion	P	The process in which a cell initiates conjugation with cellular fusion. Conjugation with cellular fusion is the process that results in the union of cellular and genetic information from compatible mating types.
10515	negative regulation of induction of conjugation with cellular fusion	P	Any process that stops, prevents, or reduces the frequency or rate of initiation of conjugation with cellular fusion.
10516	negative regulation of cellular response to nitrogen starvation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of a cellular response to nitrogen starvation.
10517	regulation of phospholipase activity	P	Any process that modulates the frequency, rate or extent of phospholipase activity, the hydrolysis of a phospholipid.
10518	positive regulation of phospholipase activity	P	Any process that increases the frequency, rate or extent of phospholipase activity, the hydrolysis of a phospholipid.
10519	negative regulation of phospholipase activity	P	Any process that decreases the frequency, rate or extent of phospholipase activity, the hydrolysis of a phospholipid.
10520	regulation of reciprocal meiotic recombination	P	Any process that modulates the frequency, rate or extent of recombination during meiosis. Reciprocal meiotic recombination is the cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate.
10521	telomerase inhibitor activity	F	Stops, prevents or reduces the activity of a telomerase. Telomerase catalyzes the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). Catalyzes extension of the 3'- end of a DNA strand by one deoxynucleotide at a time using an internal RNA template that encodes the telomeric repeat sequence.
10522	regulation of calcium ion transport into cytosol	P	Any process that modulates the rate of the directed movement of calcium ions into the cytosol of a cell. The cytosol is that part of the cytoplasm that does not contain membranous or particulate subcellular components.
10523	negative regulation of calcium ion transport into cytosol	P	Any process that decreases the rate of the directed movement of calcium ions into the cytosol of a cell. The cytosol is that part of the cytoplasm that does not contain membranous or particulate subcellular components.
10524	positive regulation of calcium ion transport into cytosol	P	Any process that increases the rate of the directed movement of calcium ions into the cytosol of a cell. The cytosol is that part of the cytoplasm that does not contain membranous or particulate subcellular components.
10525	regulation of transposition, RNA-mediated	P	Any process that modulates the frequency, rate or extent of RNA-mediated transposition. RNA-mediated transposition is a type of transpositional recombination which occurs via an RNA intermediate.
10526	negative regulation of transposition, RNA-mediated	P	Any process that decreases the frequency, rate or extent of RNA-mediated transposition. RNA-mediated transposition is a type of transpositional recombination which occurs via an RNA intermediate.
10527	positive regulation of transposition, RNA-mediated	P	Any process that increases the frequency, rate or extent of RNA-mediated transposition. RNA-mediated transposition is a type of transpositional recombination which occurs via an RNA intermediate.
10528	regulation of transposition	P	Any process that modulates the frequency, rate or extent of transposition. Transposition results in the movement of discrete segments of DNA between nonhomologous sites.
10529	negative regulation of transposition	P	Any process that decreases the frequency, rate or extent of transposition. Transposition results in the movement of discrete segments of DNA between nonhomologous sites.
10530	positive regulation of transposition	P	Any process that increases the frequency, rate or extent of transposition. Transposition results in the movement of discrete segments of DNA between nonhomologous sites.
10531	activation of JAK1 kinase activity	P	The process of introducing a phosphate group to a tyrosine residue of a JAK1 (Janus Activated Kinase 1) protein, thereby activating it.
10532	regulation of activation of JAK1 kinase activity	P	Any process that modulates the frequency or rate of activation of JAK1 protein. The activation of JAK1 protein is the process of introducing a phosphate group to a tyrosine residue of a JAK1 (Janus Activated Kinase 1) protein, thereby activating it.
10533	regulation of activation of Janus kinase activity	P	Any process that modulates the frequency or rate of activation of JAK protein. The activation of JAK protein is the process of introducing a phosphate group to a tyrosine residue of a JAK (Janus Activated Kinase) protein, thereby activating it.
10534	regulation of activation of JAK2 kinase activity	P	Any process that modulates the frequency or rate of activation of JAK2 protein. The activation of JAK2 protein is the process of introducing a phosphate group to a tyrosine residue of a JAK2 (Janus Activated Kinase 2) protein, thereby activating it.
10535	positive regulation of activation of JAK2 kinase activity	P	Any process that increase the frequency or rate of activation of JAK2 protein. The activation of JAK2 protein is the process of introducing a phosphate group to a tyrosine residue of a JAK2 (Janus Activated Kinase 2) protein, thereby activating it.
10536	positive regulation of activation of Janus kinase activity	P	Any process that increases the frequency or rate of activation of JAK protein. The activation of JAK protein is the process of introducing a phosphate group to a tyrosine residue of a JAK (Janus Activated Kinase) protein, thereby activating it.
10537	positive regulation of activation of JAK1 kinase activity	P	Any process that increases the frequency or rate of activation of JAK1 protein. The activation of JAK1 protein is the process of introducing a phosphate group to a tyrosine residue of a JAK1 (Janus Activated Kinase 1) protein, thereby activating it.
10540	basipetal auxin transport	P	The unidirectional movement of auxin from the apex to base of an organ, including the shoot, leaf, primary root, or lateral root.
10541	acropetal auxin transport	P	The unidirectional movement of auxin from the base towards the apex of an organ, including the shoot, leaf, primary root, or lateral root.
10542	nitrate efflux transmembrane transporter activity	F	Enables the transfer of nitrate from the inside of the cell to the outside of the cell across a membrane.
10543	regulation of platelet activation	P	Any process that modulates the rate or frequency of platelet activation. Platelet activation is a series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue.
10544	negative regulation of platelet activation	P	Any process that decreases the rate or frequency of platelet activation. Platelet activation is a series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue.
10547	thylakoid membrane disassembly	P	The controlled breakdown of the thylakoid membrane in the context of a normal process.
10548	regulation of thylakoid membrane disassembly	P	Any process that modulates the frequency, rate or extent of thylakoid membrane disassembly.
10549	regulation of membrane disassembly	P	Any process that modulates the frequency, rate or extent of membrane disassembly.
10550	regulation of PSII associated light-harvesting complex II catabolic process	P	Any process that modulates the chemical reactions and pathways resulting in the breakdown of one or more components of the light-harvesting complex of photosystem II.
10555	response to mannitol	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mannitol stimulus.
10556	regulation of macromolecule biosynthetic process	P	Any process that modulates the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
10557	positive regulation of macromolecule biosynthetic process	P	Any process that increases the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
10558	negative regulation of macromolecule biosynthetic process	P	Any process that decreases the rate, frequency or extent of the chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
10559	regulation of glycoprotein biosynthetic process	P	Any process that modulates the rate, frequency, or extent of the chemical reactions and pathways resulting in the formation of glycoproteins, any protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide.
10560	positive regulation of glycoprotein biosynthetic process	P	Any process that increases the rate, frequency, or extent of the chemical reactions and pathways resulting in the formation of glycoproteins, any protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide.
10561	negative regulation of glycoprotein biosynthetic process	P	Any process that decreases the rate, frequency, or extent of the chemical reactions and pathways resulting in the formation of glycoproteins, any protein that contains covalently bound glycose (i.e. monosaccharide) residues; the glycose occurs most commonly as oligosaccharide or fairly small polysaccharide but occasionally as monosaccharide.
10562	positive regulation of phosphorus metabolic process	P	Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving phosphorus or compounds containing phosphorus.
10563	negative regulation of phosphorus metabolic process	P	Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving phosphorus or compounds containing phosphorus.
10564	regulation of cell cycle process	P	Any process that modulates a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events.
10565	regulation of cellular ketone metabolic process	P	Any process that modulates the chemical reactions and pathways involving any of a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups.
10566	regulation of ketone biosynthetic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of a ketone, carried out by individual cells.
10567	regulation of ketone catabolic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a ketone, carried out by individual cells.
10568	regulation of budding cell apical bud growth	P	Any process that modulates the frequency, rate or extent of growth at the tip of a bud, in a cell that reproduces by budding.
10569	regulation of double-strand break repair via homologous recombination	P	Any process that modulates the frequency, rate or extent of the error-free repair of a double-strand break in DNA in which the broken DNA molecule is repaired using homologous sequences.
10570	regulation of filamentous growth	P	Any process that modulates the frequency, rate or extent of the process in which a multicellular organism or a group of unicellular organisms grow in a threadlike, filamentous shape.
10571	positive regulation of nuclear cell cycle DNA replication	P	Any process that activates or increases the frequency, rate or extent of The DNA-dependent DNA replication that occurs in the nucleus of eukaryotic organisms as part of the cell cycle.
10572	positive regulation of platelet activation	P	Any process that increases the rate or frequency of platelet activation. Platelet activation is a series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue.
10573	vascular endothelial growth factor production	P	The appearance of vascular endothelial growth factor production due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
10574	regulation of vascular endothelial growth factor production	P	Any process that modulates the frequency, rate, or extent of production of vascular endothelial growth factor.
10575	positive regulation of vascular endothelial growth factor production	P	Any process that increases or activates the frequency, rate, or extent of production of vascular endothelial growth factor.
10578	regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway	P	Any process that modulates the frequency, rate or extent of adenylate cyclase (AC) activity that is an integral part of a G-protein coupled receptor signaling pathway.
10579	positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway	P	Any process that increases the frequency, rate or extent of adenylate cyclase (AC) activity that is an integral part of a G-protein coupled receptor signaling pathway.
10581	regulation of starch biosynthetic process	P	An process which modulate the frequency, rate or extent of starch biosynthesis, the chemical reactions and pathways resulting in the formation of starch.
10582	floral meristem determinacy	P	The process in which a floral meristem becomes determinate (i.e. ceases to produce lateral organs and may or may not terminally differentiate).
10583	response to cyclopentenone	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cyclopentenone stimulus. Cyclopentenones are oxylipins derived from polyunsaturated fatty acids. They are structurally similar to jasmonic acid, but contain a reactive unsaturated carbonyl structure in the cyclo-ring. Cyclopentenones include phytoprostanes and 12-oxo-phytodienoic acid.
10584	pollen exine formation	P	The formation of the pollen exine. The reticulate pollen wall pattern consists of two layers, exine and intine.
10585	glutamine secretion	P	The controlled release of glutamine by a cell.
10586	miRNA metabolic process	P	The chemical reactions and pathways involving miRNA, microRNA, a class of single-stranded RNA molecules of about 21-23 nucleotides in length, which regulates gene expression.
10587	miRNA catabolic process	P	The chemical reactions and pathways resulting in the breakdown of miRNA, microRNA, a class of single-stranded RNA molecules of about 21-23 nucleotides in length, which regulates gene expression.
10588	cotyledon vascular tissue pattern formation	P	Vascular tissue pattern formation as it occurs in the cotyledon of vascular plants.
10589	leaf proximal/distal pattern formation	P	The regionalization process within a leaf by which specific areas of cell differentiation are determined along a proximal/distal axis.
10590	regulation of cell separation after cytokinesis	P	Any process that modulates the rate, frequency or extent of the process of physically separating progeny cells after cytokinesis; this may involve enzymatic digestion of septum or cell wall components.
10591	regulation of lamellipodium assembly	P	Any process that modulates the rate, frequency or extent of the formation of a lamellipodium, a thin sheetlike extension of the surface of a migrating cell.
10592	positive regulation of lamellipodium assembly	P	Any process that increases the rate, frequency or extent of the formation of a lamellipodium, a thin sheetlike extension of the surface of a migrating cell.
10593	negative regulation of lamellipodium assembly	P	Any process that decreases the rate, frequency or extent of the formation of a lamellipodium, a thin sheetlike extension of the surface of a migrating cell.
10594	regulation of endothelial cell migration	P	Any process that modulates the rate, frequency, or extent of the orderly movement of an endothelial cell into the extracellular matrix to form an endothelium.
10595	positive regulation of endothelial cell migration	P	Any process that increases the rate, frequency, or extent of the orderly movement of an endothelial cell into the extracellular matrix to form an endothelium.
10596	negative regulation of endothelial cell migration	P	Any process that decreases the rate, frequency, or extent of the orderly movement of an endothelial cell into the extracellular matrix to form an endothelium.
10597	green leaf volatile biosynthetic process	P	The chemical reactions and pathways resulting in the formation of volatile molecules emitted from green plants, such as hexenal, hexenol and hexenyl acetate, from linoleic acid or linolenic acid.
10598	NAD(P)H dehydrogenase complex (plastoquinone)	C	Complex that possesses NAD(P)H dehydrogenase (plastoquinone) activity. The complex is one of the components of the electron transport chain. It is involved in electron transport from an unidentified electron donor, possibly NADH, NADPH or ferredoxin(Fd) to the plastoquinone pool.
10599	production of lsiRNA involved in RNA interference	P	Cleavage of double-stranded RNA to form lsiRNA (long small interfering RNA), a class of siRNAs 30 to 40 nt in length. lsiRNAs are induced by pathogen infection or under specific growth conditions.
10600	regulation of auxin biosynthetic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of auxins, plant hormones that regulate aspects of plant growth.
10601	positive regulation of auxin biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of auxins, plant hormones that regulate aspects of plant growth.
10602	regulation of 1-aminocyclopropane-1-carboxylate metabolic process	P	Regulation of the chemical reactions and pathways involving 1-aminocyclopropane-1-carboxylate, the anion of 1-aminocyclopropane-1-carboxylic acid, a natural product found in plant tissues. It is a key intermediate in the biosynthesis of ethylene (ethene), a fruit-ripening hormone in plants.
10603	regulation of cytoplasmic mRNA processing body assembly	P	Any process that modulates the rate, frequency, or extent of the aggregation, arrangement and bonding together of proteins and RNA molecules to form a cytoplasmic mRNA processing body.
10604	positive regulation of macromolecule metabolic process	P	Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
10605	negative regulation of macromolecule metabolic process	P	Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
10606	positive regulation of cytoplasmic mRNA processing body assembly	P	Any process that increases the rate, frequency, or extent of the aggregation, arrangement and bonding together of proteins and RNA molecules to form a cytoplasmic mRNA processing body.
10607	negative regulation of cytoplasmic mRNA processing body assembly	P	Any process that decreases the rate, frequency, or extent of the aggregation, arrangement and bonding together of proteins and RNA molecules to form a cytoplasmic mRNA processing body.
10608	posttranscriptional regulation of gene expression	P	Any process that modulates the frequency, rate or extent of gene expression after the production of an RNA transcript.
10609	mRNA localization resulting in posttranscriptional regulation of gene expression	P	Any process that modulates the frequency, rate or extent of gene expression after the production of a mRNA transcript by its transport into, or maintainance in, a specific location within the cell.
10610	regulation of mRNA stability involved in response to stress	P	Any process that modulates the propensity of mRNA molecules to degradation that is part of a change in state or activity of a cell as a result of an exogenous disturbance.
10611	regulation of cardiac muscle hypertrophy	P	Any process that modulates the rate, frequency or extent of the enlargement or overgrowth of all or part of the heart due to an increase in size (not length) of individual cardiac muscle fibers, without cell division.
10612	regulation of cardiac muscle adaptation	P	Any process that modulates the rate, extent or frequency of the process in which cardiac muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors.
10613	positive regulation of cardiac muscle hypertrophy	P	Any process that increases the rate, frequency or extent of the enlargement or overgrowth of all or part of the heart due to an increase in size (not length) of individual cardiac muscle fibers, without cell division.
10614	negative regulation of cardiac muscle hypertrophy	P	Any process that decreases the rate, frequency or extent of the enlargement or overgrowth of all or part of the heart due to an increase in size (not length) of individual cardiac muscle fibers, without cell division.
10615	positive regulation of cardiac muscle adaptation	P	Any process that increases the rate, extent or frequency of the process in which cardiac muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors.
10616	negative regulation of cardiac muscle adaptation	P	Any process that decreases the rate, extent or frequency of the process in which cardiac muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors.
10617	circadian regulation of calcium ion oscillation	P	Any process that modulates the concentration of cytosolic free calcium ion [Ca2+]cyt with a regularity of approximately 24 hours.
10618	aerenchyma formation	P	The process that gives rise to aerenchyma, parenchyma tissue containing particularly large intercellular spaces of schizogenous or lysigenous origin. This process pertains to the initial formation of a structure from unspecified parts.
10619	adenylate cyclase-activating glucose-activated G-protein coupled receptor signaling pathway	P	The series of molecular signals generated as a consequence of glucose binding to a G-protein coupled receptor, where the pathway proceeds with activation of adenylyl cyclase and a subsequent increase in the concentration of cyclic AMP (cAMP).
10620	negative regulation of transcription by transcription factor catabolism	P	Any process that stops, prevents, or reduces the frequency, rate or extent of DNA-dependent transcription using a mechanism that involves the catabolism of a sequence-specific DNA binding transcription factor by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome.
10621	negative regulation of transcription by transcription factor localization	P	Any process that stops, prevents, or reduces the frequency, rate or extent of DNA-dependent transcription using a mechanism that involves the localization of a transcription factor.
10622	specification of ovule identity	P	The regionalization process in which the identity of an ovule is specified. Identity is considered to be the aggregate of characteristics by which a structure is recognized.
10623	programmed cell death involved in cell development	P	The activation of endogenous cellular processes that result in the death of a cell as part of its development.
10624	regulation of Schwann cell proliferation	P	Any process that modulates the frequency or rate of multiplication or reproduction of Schwann cells, resulting in the expansion of their population. Schwann cells are a type of glial cell in the peripheral nervous system.
10625	positive regulation of Schwann cell proliferation	P	Any process that increases the frequency or rate of the multiplication or reproduction of Schwann cells, resulting in the expansion of their population. Schwann cells are a type of glial cell in the peripheral nervous system.
10626	negative regulation of Schwann cell proliferation	P	Any process that decreases the frequency or extent of the multiplication or reproduction of Schwann cells, resulting in the expansion of their population. Schwann cells are a type of glial cell in the peripheral nervous system.
10628	positive regulation of gene expression	P	Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
10629	negative regulation of gene expression	P	Any process that decreases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
10630	regulation of transcription, start site selection	P	Any process that modulates the frequency, rate or extent of the synthesis of either RNA on a template of DNA or DNA on a template of RNA by a mechanism that selects the start site along that template.
10631	epithelial cell migration	P	The orderly movement of an epithelial cell from one site to another, often during the development of a multicellular organism.
10632	regulation of epithelial cell migration	P	Any process that modulates the frequency, rate or extent of epithelial cell migration.
10633	negative regulation of epithelial cell migration	P	Any process that stops, prevents, or reduces the frequency, rate or extent of epithelial cell migration.
10634	positive regulation of epithelial cell migration	P	Any process that activates or increases the frequency, rate or extent of epithelial cell migration.
10635	regulation of mitochondrial fusion	P	Any process that modulates the frequency, rate or extent of merging of two or more mitochondria within a cell to form a single compartment.
10636	positive regulation of mitochondrial fusion	P	Any process that increases the frequency, rate or extent of merging of two or more mitochondria within a cell to form a single compartment.
10637	negative regulation of mitochondrial fusion	P	Any process that decreases the frequency, rate or extent of merging of two or more mitochondria within a cell to form a single compartment.
10638	positive regulation of organelle organization	P	Any process that increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of an organelle.
10639	negative regulation of organelle organization	P	Any process that decreases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of an organelle.
10640	regulation of platelet-derived growth factor receptor signaling pathway	P	Any process that modulates the frequency, rate or extent of the platelet-derived growth factor receptor signaling pathway.
10641	positive regulation of platelet-derived growth factor receptor signaling pathway	P	Any process that increases the frequency, rate or extent of the platelet-derived growth factor receptor signaling pathway.
10642	negative regulation of platelet-derived growth factor receptor signaling pathway	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the platelet-derived growth factor receptor signaling pathway.
10643	cell communication by chemical coupling	P	The process that mediates signaling interactions between one cell and another cell by the transfer of small, water-soluble molecules or metabolites between their adjacent cytoplasms via intercellular protein channels.
10644	cell communication by electrical coupling	P	The process that mediates signaling interactions between one cell and another cell by transfer of current between their adjacent cytoplasms via intercellular protein channels.
10645	regulation of cell communication by chemical coupling	P	Any process that modulates the frequency, rate or extent of cell communication via chemical coupling. Cell communication by chemical coupling is the process that mediates signaling interactions between one cell and another cell by the transfer of small, water-soluble molecules or metabolites between their adjacent cytoplasms via intercellular protein channels.
10646	regulation of cell communication	P	Any process that modulates the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.
10647	positive regulation of cell communication	P	Any process that increases the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.
10648	negative regulation of cell communication	P	Any process that decreases the frequency, rate or extent of cell communication. Cell communication is the process that mediates interactions between a cell and its surroundings. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.
10649	regulation of cell communication by electrical coupling	P	Any process that modulates the frequency, rate or extent of cell communication via electrical coupling. Cell communication via electrical coupling is the process that mediates signaling interactions between one cell and another cell by transfer of current between their adjacent cytoplasms via intercellular protein channels.
10650	positive regulation of cell communication by electrical coupling	P	Any process that increases the frequency, rate or extent of cell communication via electrical coupling. Cell communication via electrical coupling is the process that mediates signaling interactions between one cell and another cell by transfer of current between their adjacent cytoplasms via intercellular protein channels.
10651	negative regulation of cell communication by electrical coupling	P	Any process that decreases the frequency, rate or extent of cell communication via electrical coupling. Cell communication via electrical coupling is the process that mediates signaling interactions between one cell and another cell by transfer of current between their adjacent cytoplasms via intercellular protein channels.
10652	positive regulation of cell communication by chemical coupling	P	Any process that increases the frequency, rate or extent of cell communication via chemical coupling. Cell communication by chemical coupling is the process that mediates signaling interactions between one cell and another cell by the transfer of small, water-soluble molecules or metabolites between their adjacent cytoplasms via intercellular protein channels.
10653	negative regulation of cell communication by chemical coupling	P	Any process that decreases the frequency, rate or extent of cell communication via chemical coupling. Cell communication by chemical coupling is the process that mediates signaling interactions between one cell and another cell by the transfer of small, water-soluble molecules or metabolites between their adjacent cytoplasms via intercellular protein channels.
10654	apical cell fate commitment	P	The process in which the developmental fate of a cell becomes restricted such that it will develop into an apical cell. The apical cell is the upper cell formed after the first division of the zygote.
10656	negative regulation of muscle cell apoptotic process	P	Any process that decreases the rate or frequency of muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a muscle cell and result in its death.
10657	muscle cell apoptotic process	P	A form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases, whose actions dismantle a muscle cell and result in its death. A muscle cell is a mature contractile cell, commonly known as a myocyte, that forms one of three kinds of muscle.
10658	striated muscle cell apoptotic process	P	A form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases, whose actions dismantle a striated muscle cell and result in its death. Striated muscle cells make up striated muscle fibers which are divided by transverse bands into striations.
10659	cardiac muscle cell apoptotic process	P	A form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases, whose actions dismantle a cardiac muscle cell and result in its death. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction.
10660	regulation of muscle cell apoptotic process	P	Any process that modulates the rate or frequency of muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a muscle cell and result in its death.
10661	positive regulation of muscle cell apoptotic process	P	Any process that increases the rate or frequency of muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a muscle cell and result in its death.
10662	regulation of striated muscle cell apoptotic process	P	Any process that modulates the rate or extent of striated muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a striated muscle cell and result in its death.
10663	positive regulation of striated muscle cell apoptotic process	P	Any process that increases the rate or extent of striated muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a striated muscle cell and result in its death.
10664	negative regulation of striated muscle cell apoptotic process	P	Any process that decreases the rate or extent of striated muscle cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a striated muscle cell and result in its death.
10665	regulation of cardiac muscle cell apoptotic process	P	Any process that modulates the rate or extent of cardiac cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a cardiac muscle cell and result in its death.
10666	positive regulation of cardiac muscle cell apoptotic process	P	Any process that increases the rate or extent of cardiac cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a cardiac muscle cell and result in its death.
10667	negative regulation of cardiac muscle cell apoptotic process	P	Any process that decreases the rate or extent of cardiac cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a cardiac muscle cell and result in its death.
10668	ectodermal cell differentiation	P	The process in which relatively unspecialized cells acquire specialized structural and/or functional features of an ectodermal cell. Differentiation includes the processes involved in commitment of a cell to a specific fate.
10669	epithelial structure maintenance	P	A tissue homeostatic process required for the maintenance of epithelial structure.
10672	regulation of transcription from RNA polymerase II promoter involved in meiotic cell cycle	P	A cell cycle process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter as part of the meiotic cell cycle.
10673	positive regulation of transcription from RNA polymerase II promoter involved in meiotic cell cycle	P	A cell cycle process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as part of the meiotic cell cycle.
10674	negative regulation of transcription from RNA polymerase II promoter involved in meiotic cell cycle	P	A cell cycle process that decreases the frequency, rate or extent of transcription from an RNA polymerase II as part of the meiotic cell cycle.
10675	regulation of cellular carbohydrate metabolic process	P	Any process that modulates the rate, extent or frequency of the chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y, as carried out by individual cells.
10676	positive regulation of cellular carbohydrate metabolic process	P	Any process that increases the rate, extent or frequency of the chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y, as carried out by individual cells.
10677	negative regulation of cellular carbohydrate metabolic process	P	Any process that decreases the rate, extent or frequency of the chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y, as carried out by individual cells.
10678	negative regulation of cellular carbohydrate metabolic process by negative regulation of transcription, DNA-templated	P	Any cellular process that decreases the rate, extent or frequency of the chemical reactions and pathways involving carbohydrates carried out by repression of transcription.
10679	cinnamic acid biosynthetic process involved in salicylic acid metabolism	P	The chemical reactions and pathways resulting in the formation of cinnamic acid, 3-phenyl-2-propenoic acid, which is then utilized in the metabolism of salicylic acid.
10680	cinnamic acid biosynthetic process involved in coumarin metabolism	P	The chemical reactions and pathways resulting in the formation of cinnamic acid, 3-phenyl-2-propenoic acid, which is then utilized in the metabolism of coumarin.
10681	cinnamic acid biosynthetic process involved in stilbene metabolism	P	The chemical reactions and pathways resulting in the formation of cinnamic acid, 3-phenyl-2-propenoic acid, which is then utilized in the metabolism of stilbene.
10682	cinnamic acid biosynthetic process involved in flavonoid metabolism	P	The chemical reactions and pathways resulting in the formation of cinnamic acid, 3-phenyl-2-propenoic acid, which is then utilized in the metabolism of flavonoids.
10683	tricyclic triterpenoid metabolic process	P	The chemical reactions and pathways involving tricyclic triterpenoid compounds, terpenoids with six isoprene units and 3 rings.
10684	tricyclic triterpenoid catabolic process	P	The chemical reactions and pathways resulting in the breakdown of tricyclic triterpenoid compounds, terpenoids with six isoprene units and 3 rings.
10685	tetracyclic triterpenoid metabolic process	P	The chemical reactions and pathways involving tetracyclic triterpenoid compounds, terpenoids with six isoprene units and 4 carbon rings.
10686	tetracyclic triterpenoid biosynthetic process	P	The chemical reactions and pathways resulting in the formation of tetracyclic triterpenoid compounds, terpenoids with six isoprene units and 4 carbon rings.
10688	negative regulation of ribosomal protein gene transcription from RNA polymerase II promoter	P	Any process that decreases the frequency, rate or extent of the synthesis of RNA from ribosomal protein genes by RNA polymerase II, originating at an RNA polymerase II promoter.
10689	negative regulation of ribosomal protein gene transcription from RNA polymerase II promoter in response to chemical stimulus	P	Any process that decreases the frequency, rate or extent of the synthesis of RNA from ribosomal protein genes by RNA polymerase II, originating at an RNA polymerase II promoter, as a result of a chemical stimulus.
10690	negative regulation of ribosomal protein gene transcription from RNA polymerase II promoter in response to stress	P	Any process that decreases the frequency, rate or extent of the synthesis of RNA from ribosomal protein genes by RNA polymerase II, originating at an RNA polymerase II promoter, as a result of a disturbance in organismal or cellular homeostasis.
10691	negative regulation of ribosomal protein gene transcription from RNA polymerase II promoter in response to nutrient levels	P	Any process that decreases the frequency, rate or extent of the synthesis of RNA from ribosomal protein genes by RNA polymerase II, originating at an RNA polymerase II promoter, as a result of a stimulus reflecting the presence, absence, or concentration of nutrients.
10692	regulation of alkaline phosphatase activity	P	Any process that modulates the frequency, rate or extent of alkaline phosphatase activity, the catalysis of the reaction: an orthophosphoric monoester + H2O = an alcohol + phosphate, with an alkaline pH optimum.
10693	negative regulation of alkaline phosphatase activity	P	Any process that decreases the frequency, rate or extent of alkaline phosphatase activity, the catalysis of the reaction: an orthophosphoric monoester + H2O = an alcohol + phosphate, with an alkaline pH optimum.
10694	positive regulation of alkaline phosphatase activity	P	Any process that increases the frequency, rate or extent of alkaline phosphatase activity, the catalysis of the reaction: an orthophosphoric monoester + H2O = an alcohol + phosphate, with an alkaline pH optimum.
10695	regulation of spindle pole body separation	P	Any process that modulates the rate, frequency or extent of the process involving the release of duplicated spindle pole bodies (SPBs) and their migration away from each other within the nuclear membrane.
10696	positive regulation of spindle pole body separation	P	Any process that increases the rate, frequency or extent of the process involving the release of duplicated spindle pole bodies (SPBs) and their migration away from each other within the nuclear membrane.
10697	negative regulation of spindle pole body separation	P	Any process that decreases the rate, frequency or extent of the process involving the release of duplicated spindle pole bodies (SPBs) and their migration away from each other within the nuclear membrane.
10698	acetyltransferase activator activity	F	Binds to and increases the activity of an acetyltransferase, an enzyme which catalyzes the transfer of an acetyl group to an acceptor molecule.
10699	cell-cell signaling involved in quorum sensing	P	The cell-cell signaling process in which single-celled organisms monitor population density by detecting the concentration of small diffusible signal molecules.
10700	negative regulation of norepinephrine secretion	P	Any process that decreases the frequency, rate or extent of the regulated release of norepinephrine.
10701	positive regulation of norepinephrine secretion	P	Any process that increases the frequency, rate or extent of the regulated release of norepinephrine.
10704	meiotic DNA double-strand break processing involved in meiotic gene conversion	P	The cell cycle process in which the 5' to 3' exonucleolytic resection of the DNA at the site of the break to form a 3' single-strand DNA overhang resulting in the transfer of genetic information from one helix to another.
10705	meiotic DNA double-strand break processing involved in reciprocal meiotic recombination	P	The cell cycle process in which the 5' to 3' exonucleolytic resection of the DNA at the site of the break to form a 3' single-strand DNA overhang occurs resulting in double strand break formation and repair through a double Holliday junction intermediate.
10706	ganglioside biosynthetic process via lactosylceramide	P	The chemical reactions and pathways resulting in the formation of gangliosides that begins with the formation of lactosylceramides, Gal-beta-(1->4)-Glc-beta-(1->1') ceramides, any compound formed by the replacement of the glycosidic C1 hydroxyl group of lactose by a ceramide group.
10707	globoside biosynthetic process via lactosylceramide	P	The chemical reactions and pathways resulting in the formation of globosides that begins with the formation of lactosylceramides, Gal-beta-(1->4)-Glc-beta-(1->1') ceramides, any compound formed by the replacement of the glycosidic C1 hydroxyl group of lactose by a ceramide group.
10708	heteroduplex formation involved in gene conversion at mating-type locus	P	The formation of a stable duplex DNA that contains one strand from each of the two recombining DNA molecules resulting in the conversion of the mating-type locus from one allele to another.
10709	heteroduplex formation involved in double-strand break repair via synthesis-dependent strand annealing	P	The formation of a stable duplex DNA that contains one strand from each of the two recombining DNA molecules resulting in the error-free repair of a double-strand break without the exchange of adjacent sequences.
10710	regulation of collagen catabolic process	P	Any process that modulates the rate, frequency or extent of collagen catabolism. Collagen catabolism is the proteolytic chemical reactions and pathways resulting in the breakdown of collagen in the extracellular matrix.
10711	negative regulation of collagen catabolic process	P	Any process that decreases the rate, frequency or extent of collagen catabolism. Collagen catabolism is the proteolytic chemical reactions and pathways resulting in the breakdown of collagen in the extracellular matrix.
10712	regulation of collagen metabolic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the metabolism of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals.
10713	negative regulation of collagen metabolic process	P	Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the metabolism of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals.
10714	positive regulation of collagen metabolic process	P	Any process that increases the frequency, rate or extent of the chemical reactions and pathways resulting in the metabolism of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals.
10715	regulation of extracellular matrix disassembly	P	Any process that modulates the rate, frequency or extent of extracellular matrix disassembly. Extracellular matrix disassembly is a process that results in the breakdown of the extracellular matrix.
10716	negative regulation of extracellular matrix disassembly	P	Any process that decreases the rate, frequency or extent of extracellular matrix disassembly. Extracellular matrix disassembly is a process that results in the breakdown of the extracellular matrix.
10717	regulation of epithelial to mesenchymal transition	P	Any process that modulates the rate, frequency, or extent of epithelial to mesenchymal transition. Epithelial to mesenchymal transition where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell.
10718	positive regulation of epithelial to mesenchymal transition	P	Any process that increases the rate, frequency, or extent of epithelial to mesenchymal transition. Epithelial to mesenchymal transition is where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell.
10719	negative regulation of epithelial to mesenchymal transition	P	Any process that decreases the rate, frequency, or extent of epithelial to mesenchymal transition. Epithelial to mesenchymal transition where an epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell.
10720	positive regulation of cell development	P	Any process that increases the rate, frequency or extent of the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate.
10721	negative regulation of cell development	P	Any process that decreases the rate, frequency or extent of the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate.
10722	regulation of ferrochelatase activity	P	Any process that modulates the frequency, rate or extent of ferrochelatase activity; catalysis of the reaction: protoporphyrin + Fe2+ = protoheme + 2 H+.
10723	positive regulation of transcription from RNA polymerase II promoter in response to iron	P	Any process that increases the rate of transcription from an RNA polymerase II promoter in response to an iron stimulus.
10724	regulation of definitive erythrocyte differentiation	P	Any process that modulates the rate, frequency, or extent of definitive erythrocyte differentiation. Definitive erythrocyte differentiation occurs as part of the process of definitive hemopoiesis.
10725	regulation of primitive erythrocyte differentiation	P	Any process that modulates the rate, frequency, or extent of primitive erythrocyte differentiation. Primitive erythrocyte differentiation occurs as part of the process of primitive hemopoiesis.
10726	positive regulation of hydrogen peroxide metabolic process	P	Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving hydrogen peroxide.
10727	negative regulation of hydrogen peroxide metabolic process	P	Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving hydrogen peroxide.
10728	regulation of hydrogen peroxide biosynthetic process	P	Any process that modulates the rate, frequency or extent of hydrogen peroxide biosynthesis. The chemical reactions and pathways resulting in the formation of hydrogen peroxide (H2O2), a potentially harmful byproduct of aerobic cellular respiration which can cause damage to DNA.
10729	positive regulation of hydrogen peroxide biosynthetic process	P	Any process that increases the rate, frequency or extent of hydrogen peroxide biosynthesis. The chemical reactions and pathways resulting in the formation of hydrogen peroxide (H2O2), a potentially harmful byproduct of aerobic cellular respiration which can cause damage to DNA.
10730	negative regulation of hydrogen peroxide biosynthetic process	P	Any process that decreases the rate, frequency or extent of hydrogen peroxide biosynthesis. The chemical reactions and pathways resulting in the formation of hydrogen peroxide (H2O2), a potentially harmful byproduct of aerobic cellular respiration which can cause damage to DNA.
10731	protein glutathionylation	P	The protein modification process in which a glutathione molecule is added to a protein amino acid through a disulfide linkage.
10732	regulation of protein glutathionylation	P	Any process that modulates the rate, frequency, or extent of protein glutathionylation. Protein glutathionylation is the protein modification process in which a glutathione molecule is added to a protein amino acid through a disulfide linkage.
10733	positive regulation of protein glutathionylation	P	Any process that increases the rate, frequency, or extent of protein glutathionylation. Protein glutathionylation is the protein modification process in which a glutathione molecule is added to a protein amino acid through a disulfide linkage.
10734	negative regulation of protein glutathionylation	P	Any process that decreases the rate, frequency, or extent of protein glutathionylation. Protein glutathionylation is the protein modification process in which a glutathione molecule is added to a protein amino acid through a disulfide linkage.
10735	positive regulation of transcription via serum response element binding	P	Any process that increases the frequency, rate or extent of the specifically regulated synthesis of RNA from DNA encoding a specific set of genes as a result of a transcription factor interacting with a serum response element (SRE). A serum response element is a short sequence with dyad symmetry found in the promoters of some of the cellular immediate-early genes, regulated by serum.
10736	serum response element binding	F	Interacting selectively and non-covalently with the serum response element (SRE), a short sequence with dyad symmetry found in the promoters of some of the cellular immediate-early genes, regulated by serum.
10737	protein kinase A signaling	P	A series of reactions, mediated by the intracellular serine/threonine kinase protein kinase A, which occurs as a result of a single trigger reaction or compound.
10738	regulation of protein kinase A signaling	P	Any process that modulates the rate, frequency, or extent of protein kinase A signaling. PKA signaling is the series of reactions, mediated by the intracellular serine/threonine kinase protein kinase A, which occurs as a result of a single trigger reaction or compound.
10739	positive regulation of protein kinase A signaling	P	Any process that increases the rate, frequency, or extent of protein kinase A signaling. PKA signaling is the series of reactions, mediated by the intracellular serine/threonine kinase protein kinase A, which occurs as a result of a single trigger reaction or compound.
10742	macrophage derived foam cell differentiation	P	The process in which a monocyte acquires the specialized features of a foam cell. A foam cell is a type of cell containing lipids in small vacuoles and typically seen in atherosclerotic lesions, as well as other conditions.
10743	regulation of macrophage derived foam cell differentiation	P	Any process that modulates the rate, frequency or extent of macrophage derived foam cell differentiation. Macrophage derived foam cell differentiation is the process in which a macrophage acquires the specialized features of a foam cell. A foam cell is a type of cell containing lipids in small vacuoles and typically seen in atherosclerotic lesions, as well as other conditions.
10744	positive regulation of macrophage derived foam cell differentiation	P	Any process that increases the rate, frequency or extent of macrophage derived foam cell differentiation. Macrophage derived foam cell differentiation is the process in which a macrophage acquires the specialized features of a foam cell. A foam cell is a type of cell containing lipids in small vacuoles and typically seen in atherosclerotic lesions, as well as other conditions.
10745	negative regulation of macrophage derived foam cell differentiation	P	Any process that decreases the rate, frequency or extent of macrophage derived foam cell differentiation. Macrophage derived foam cell differentiation is the process in which a macrophage acquires the specialized features of a foam cell. A foam cell is a type of cell containing lipids in small vacuoles and typically seen in atherosclerotic lesions, as well as other conditions.
10746	regulation of plasma membrane long-chain fatty acid transport	P	Any process that modulates the rate, frequency or extent of plasma membrane long-chain fatty acid transport. Plasma membrane long-chain fatty acid transport is the directed movement of long-chain fatty acids across the plasma membrane. A long-chain fatty acid is a fatty acid with a chain length between C13 and C22.
10747	positive regulation of plasma membrane long-chain fatty acid transport	P	Any process that increases the rate, frequency or extent of plasma membrane long-chain fatty acid transport. Plasma membrane long-chain fatty acid transport is the directed movement of long-chain fatty acids across the plasma membrane. A long-chain fatty acid is a fatty acid with a chain length between C13 and C22.
10748	negative regulation of plasma membrane long-chain fatty acid transport	P	Any process that decreases the rate, frequency or extent of plasma membrane long-chain fatty acid transport. Plasma membrane long-chain fatty acid transport is the directed movement of long-chain fatty acids across the plasma membrane.
10749	regulation of nitric oxide mediated signal transduction	P	Any process that modulates the rate, frequency or extent of nitric oxide mediated signal transduction. Nitric oxide mediated signal transduction is a series of molecular signals mediated by the detection of nitric oxide (NO).
10750	positive regulation of nitric oxide mediated signal transduction	P	Any process that increases the rate, frequency or extent of nitric oxide mediated signal transduction. Nitric oxide mediated signal transduction is a series of molecular signals mediated by the detection of nitric oxide (NO).
10751	negative regulation of nitric oxide mediated signal transduction	P	Any process that decreases the rate, frequency or extent of nitric oxide mediated signal transduction. Nitric oxide mediated signal transduction is a series of molecular signals mediated by the detection of nitric oxide (NO).
10752	regulation of cGMP-mediated signaling	P	Any process that modulates the rate, frequency or extent of cGMP-mediated signaling. cGMP-mediated signaling is a series of molecular signals in which a cell uses cyclic GMP to convert an extracellular signal into a response.
10753	positive regulation of cGMP-mediated signaling	P	Any process that increases the rate, frequency or extent of cGMP-mediated signaling. cGMP-mediated signaling is a series of molecular signals in which a cell uses cyclic GMP to convert an extracellular signal into a response.
10754	negative regulation of cGMP-mediated signaling	P	Any process that decreases the rate, frequency or extent of cGMP-mediated signaling. cGMP-mediated signaling is a series of molecular signals in which a cell uses cyclic GMP to convert an extracellular signal into a response.
10755	regulation of plasminogen activation	P	Any process that modulates the rate, frequency or extent of plasminogen activation. Plasminogen activation is the process in which plasminogen is processed to plasmin.
10756	positive regulation of plasminogen activation	P	Any process that increases the rate, frequency or extent of plasminogen activation. Plasminogen activation is the process in which plasminogen is processed to plasmin.
10757	negative regulation of plasminogen activation	P	Any process that decreases the rate, frequency or extent of plasminogen activation. Plasminogen activation is the process in which plasminogen is processed to plasmin.
10758	regulation of macrophage chemotaxis	P	Any process that modulates the rate, frequency or extent of macrophage chemotaxis. Macrophage chemotaxis is the movement of a macrophage in response to an external stimulus.
10759	positive regulation of macrophage chemotaxis	P	Any process that increases the rate, frequency or extent of macrophage chemotaxis. Macrophage chemotaxis is the movement of a macrophage in response to an external stimulus.
10760	negative regulation of macrophage chemotaxis	P	Any process that decreases the rate, frequency or extent of macrophage chemotaxis. Macrophage chemotaxis is the movement of a macrophage in response to an external stimulus.
10761	fibroblast migration	P	Cell migration that is accomplished by extension and retraction of a fibroblast pseudopodium. A fibroblast is a connective tissue cell which secretes an extracellular matrix rich in collagen and other macromolecules.
10762	regulation of fibroblast migration	P	Any process that modulates the rate, frequency or extent of fibroblast cell migration. Fibroblast cell migration is accomplished by extension and retraction of a pseudopodium.
10763	positive regulation of fibroblast migration	P	Any process that increases the rate, frequency or extent of fibroblast cell migration. Fibroblast cell migration is accomplished by extension and retraction of a pseudopodium.
10764	negative regulation of fibroblast migration	P	Any process that decreases the rate, frequency or extent of fibroblast cell migration. Fibroblast cell migration is accomplished by extension and retraction of a pseudopodium.
10765	positive regulation of sodium ion transport	P	Any process that increases the frequency, rate or extent of the directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
10766	negative regulation of sodium ion transport	P	Any process that decreases the frequency, rate or extent of the directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
10767	regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage	P	Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a UV damage stimulus.
10768	negative regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage	P	Any process that decreases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a UV damage stimulus.
10769	regulation of cell morphogenesis involved in differentiation	P	Any process that modulates the frequency, rate or extent of cell morphogenesis contributing to cell differentiation. Cell morphogenesis involved in differentiation is the change in form (cell shape and size) that occurs when relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history.
10770	positive regulation of cell morphogenesis involved in differentiation	P	Any process that increases the frequency, rate or extent of cell morphogenesis contributing to cell differentiation. Cell morphogenesis involved in differentiation is the change in form (cell shape and size) that occurs when relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history.
10771	negative regulation of cell morphogenesis involved in differentiation	P	Any process that decreases the frequency, rate or extent of cell morphogenesis contributing to cell differentiation. Cell morphogenesis involved in differentiation is the change in form (cell shape and size) that occurs when relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history.
10772	meiotic DNA recombinase assembly involved in reciprocal meiotic recombination	P	The aggregation, arrangement and bonding together of strand exchange proteins (recombinases) to form higher order oligomers on single-stranded DNA resulting in meiotic recombination. Meiotic recombination is the cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate.
10773	meiotic DNA recombinase assembly involved in meiotic gene conversion	P	The aggregation, arrangement and bonding together of strand exchange proteins (recombinases) to form higher order oligomers on single-stranded DNA resulting in meiotic gene conversion. Meiotic gene conversion is the cell cycle process in which genetic information is transferred from one helix to another.
10774	meiotic strand invasion involved in reciprocal meiotic recombination	P	The cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate resulting in meiotic recombination. Meiotic recombination is the cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate.
10775	meiotic strand invasion involved in meiotic gene conversion	P	The cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate resulting in meiotic recombination.
10776	meiotic mismatch repair involved in meiotic gene conversion	P	A system for the identification and correction of base-base mismatches, small insertion-deletion loops, and regions of heterology that are present in duplex DNA formed with strands from two recombining molecules resulting in meiotic gene conversion. Meiotic gene conversion is the cell cycle process in which genetic information is transferred from one helix to another.
10777	meiotic mismatch repair involved in reciprocal meiotic recombination	P	A system for the identification and correction of base-base mismatches, small insertion-deletion loops, and regions of heterology that are present in duplex DNA formed with strands from two recombining molecules resulting in meiotic recombination. Meiotic recombination is the cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate.
10778	meiotic DNA repair synthesis involved in reciprocal meiotic recombination	P	The synthesis of DNA proceeding from the broken 3' single-strand DNA end that uses the homologous intact duplex as the template resulting in meiotic recombination. Meiotic recombination is the cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate.
10779	meiotic DNA repair synthesis involved in meiotic gene conversion	P	The synthesis of DNA proceeding from the broken 3' single-strand DNA end that uses the homologous intact duplex as the template resulting in meiotic gene conversion. Meiotic gene conversion is the cell cycle process in which genetic information is transferred from one helix to another.
10780	meiotic DNA double-strand break formation involved in reciprocal meiotic recombination	P	The cell cycle process in which double-strand breaks are generated at defined hotspots throughout the genome during meiosis I resulting in meiotic recombination. Meiotic recombination is the cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate.
10781	meiotic DNA double-strand break formation involved in meiotic gene conversion	P	The cell cycle process in which double-strand breaks are generated at defined hotspots throughout the genome during meiosis I resulting in meiotic gene conversion. Meiotic gene conversion is the cell cycle process in which genetic information is transferred from one helix to another.
10782	proboscis morphogenesis, labial disc-derived	P	The process in which the anatomical structures of the proboscis that are derived from the labial disc are generated and organized.
10783	proboscis morphogenesis, eye-antennal disc-derived	P	The process in which the anatomical structures of the proboscis that are derived from the eye-antennal disc are generated and organized.
10784	proboscis morphogenesis, clypeo-labral disc-derived	P	The process in which the anatomical structures of the proboscis that are derived from the clypeo-labral disc are generated and organized.
10785	clathrin coating of Golgi vesicle, plasma membrane to endosome targeting	P	The addition of clathrin and adaptor proteins to Golgi membranes during the formation of transport vesicles that will move from the plasma membrane to the endosome, forming a vesicle coat.
10786	clathrin coating of Golgi vesicle, trans-Golgi to endosome targeting	P	The addition of clathrin and adaptor proteins to Golgi membranes during the formation of transport vesicles that will move from the trans-Golgi to the endosome, forming a vesicle coat.
10787	COPI coating of Golgi vesicle, inter-Golgi cisterna	P	The addition of COPI proteins and adaptor proteins to Golgi membranes during the formation of inter-Golgi cisterna transport vesicles, forming a vesicle coat.
10788	COPI coating of Golgi vesicle, cis-Golgi to rough ER	P	The addition of COPI proteins and adaptor proteins to Golgi membranes during the formation of cis-Golgi to rough ER transport vesicles, forming a vesicle coat.
10789	meiotic sister chromatid cohesion involved in meiosis I	P	The cell cycle process in which sister chromatids of a replicated chromosome are joined along the entire length of the chromosome during meiosis I.
10790	meiotic sister chromatid cohesion involved in meiosis II	P	The cell cycle process in which sister chromatids of a replicated chromosome are joined along the entire length of the chromosome during meiosis II.
10791	DNA double-strand break processing involved in repair via synthesis-dependent strand annealing	P	The 5' to 3' exonucleolytic resection of the DNA at the site of the break to form a 3' single-strand DNA overhang that results in the repair of a double strand break via synthesis-dependent strand annealing.
10792	DNA double-strand break processing involved in repair via single-strand annealing	P	The 5' to 3' exonucleolytic resection of the DNA at the site of the break to form a 3' single-strand DNA overhang that results in the repair of a double strand break via single-strand annealing.
10793	regulation of mRNA export from nucleus	P	Any process that modulates the frequency, rate or extent of the directed movement of mRNA from the nucleus to the cytoplasm.
10794	regulation of dolichol biosynthetic process	P	Any process that modulates the frequency, rate or extent of dolichol biosynthesis. Dolichol biosynthesis consists of the chemical reactions and pathways resulting in the formation of dolichols, any 2,3-dihydropolyprenol derived from four or more linked isoprene units.
10795	regulation of ubiquinone biosynthetic process	P	Any process that modulates the frequency, rate or extent of ubiquinone biosynthesis. Ubiquinone biosynthesis consists of the chemical reactions and pathways resulting in the formation of ubiquinone, a lipid-soluble electron-transporting coenzyme.
10796	regulation of multivesicular body size	P	Any process that modulates the volume of a multivesicular body, a type of late endosome in which regions of the limiting endosomal membrane invaginate to form internal vesicles.
10797	regulation of multivesicular body size involved in endosome transport	P	Any process that modulates the volume of a multivesicular body as part of the directed movement of substances from endosomes to lysosomes or vacuoles.
10798	regulation of multivesicular body size involved in ubiquitin-dependent protein catabolism	P	Any process that modulates the volume of a multivesicular body as part of the chemical reactions and pathways resulting in the breakdown of a protein or peptide covalently tagged with ubiquitin.
10799	regulation of peptidyl-threonine phosphorylation	P	Any process that modulates the frequency, rate or extent of peptidyl-threonine phosphorylation. Peptidyl-threonine phosphorylation is the phosphorylation of peptidyl-threonine to form peptidyl-O-phospho-L-threonine.
10800	positive regulation of peptidyl-threonine phosphorylation	P	Any process that increases the frequency, rate or extent of peptidyl-threonine phosphorylation. Peptidyl-threonine phosphorylation is the phosphorylation of peptidyl-threonine to form peptidyl-O-phospho-L-threonine.
10801	negative regulation of peptidyl-threonine phosphorylation	P	Any process that decreases the frequency, rate or extent of peptidyl-threonine phosphorylation. Peptidyl-threonine phosphorylation is the phosphorylation of peptidyl-threonine to form peptidyl-O-phospho-L-threonine.
10803	regulation of tumor necrosis factor-mediated signaling pathway	P	Any process that modulates the rate or extent of the tumor necrosis factor-mediated signaling pathway. The tumor necrosis factor-mediated signaling pathway is the series of molecular signals generated as a consequence of tumor necrosis factor binding to a cell surface receptor.
10804	negative regulation of tumor necrosis factor-mediated signaling pathway	P	Any process that decreases the rate or extent of the tumor necrosis factor-mediated signaling pathway. The tumor necrosis factor-mediated signaling pathway is the series of molecular signals generated as a consequence of tumor necrosis factor binding to a cell surface receptor.
10805	regulation of lysine import	P	Any process that modulates the rate or frequency of lysine import. Lysine import is the directed movement of lysine, 2,6-diaminohexanoic acid, into a cell or organelle.
10806	negative regulation of lysine import	P	Any process that decreases the rate or frequency of lysine import. Lysine import is the directed movement of lysine, 2,6-diaminohexanoic acid, into a cell or organelle.
10807	regulation of synaptic vesicle priming	P	Any process that modulates the frequency, rate or extent of synaptic vesicle priming. Synaptic vesicle priming is the formation of SNARE-containing complexes, bringing synaptic vesicle membrane and plasma membranes into close proximity and thereby facilitating membrane fusion.
10808	positive regulation of synaptic vesicle priming	P	Any process that increases the frequency, rate or extent of synaptic vesicle priming. Synaptic vesicle priming is the formation of SNARE-containing complexes, bringing synaptic vesicle membrane and plasma membranes into close proximity and thereby facilitating membrane fusion.
10809	negative regulation of synaptic vesicle priming	P	Any process that decreases the frequency, rate or extent of synaptic vesicle priming. Synaptic vesicle priming is the formation of SNARE-containing complexes, bringing synaptic vesicle membrane and plasma membranes into close proximity and thereby facilitating membrane fusion.
10810	regulation of cell-substrate adhesion	P	Any process that modulates the frequency, rate or extent of cell-substrate adhesion. Cell-substrate adhesion is the attachment of a cell to the underlying substrate via adhesion molecules.
10811	positive regulation of cell-substrate adhesion	P	Any process that increases the frequency, rate or extent of cell-substrate adhesion. Cell-substrate adhesion is the attachment of a cell to the underlying substrate via adhesion molecules.
10812	negative regulation of cell-substrate adhesion	P	Any process that decreases the frequency, rate or extent of cell-substrate adhesion. Cell-substrate adhesion is the attachment of a cell to the underlying substrate via adhesion molecules.
10813	neuropeptide catabolic process	P	The chemical reactions and pathways resulting in the breakdown of neuropeptides. Neuropeptides are signaling peptides that travel across a synaptic junction.
10814	substance P catabolic process	P	The chemical reactions and pathways resulting in the breakdown of the neuropeptide substance P.
10815	bradykinin catabolic process	P	The chemical reactions and pathways resulting in the breakdown of the peptide bradykinin.
10816	calcitonin catabolic process	P	The chemical reactions and pathways resulting in the breakdown of the peptide calcitonin.
10817	regulation of hormone levels	P	Any process that modulates the levels of hormone within an organism or a tissue. A hormone is any substance formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells in the same organism, upon which it has a specific regulatory action.
10818	T cell chemotaxis	P	The directed movement of a T cell in response to an external stimulus. A T cell is a type of lymphocyte whose defining characteristic is the expression of a T cell receptor complex.
10819	regulation of T cell chemotaxis	P	Any process that modulates the rate, frequency or extent of T cell chemotaxis. T cell chemotaxis is the directed movement of a T cell in response to an external stimulus.
10820	positive regulation of T cell chemotaxis	P	Any process that increases the rate, frequency or extent of T cell chemotaxis. T cell chemotaxis is the directed movement of a T cell in response to an external stimulus.
10821	regulation of mitochondrion organization	P	Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a mitochondrion.
10822	positive regulation of mitochondrion organization	P	Any process that increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a mitochondrion.
10823	negative regulation of mitochondrion organization	P	Any process that decreases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a mitochondrion.
10824	regulation of centrosome duplication	P	Any process that modulates the frequency, rate or extent of centrosome duplication. Centrosome duplication is the replication of a centrosome, a structure comprised of a pair of centrioles and peri-centriolar material from which a microtubule spindle apparatus is organized.
10825	positive regulation of centrosome duplication	P	Any process that increases the frequency, rate or extent of centrosome duplication. Centrosome duplication is the replication of a centrosome, a structure comprised of a pair of centrioles and peri-centriolar material from which a microtubule spindle apparatus is organized.
10826	negative regulation of centrosome duplication	P	Any process that decreases the frequency, rate or extent of centrosome duplication. Centrosome duplication is the replication of a centrosome, a structure comprised of a pair of centrioles and peri-centriolar material from which a microtubule spindle apparatus is organized.
10827	regulation of glucose transport	P	Any process that modulates the frequency, rate or extent of glucose transport. Glucose transport is the directed movement of the hexose monosaccharide glucose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
10828	positive regulation of glucose transport	P	Any process that increases the frequency, rate or extent of glucose transport. Glucose transport is the directed movement of the hexose monosaccharide glucose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
10829	negative regulation of glucose transport	P	Any process that decreases the frequency, rate or extent of glucose transport. Glucose transport is the directed movement of the hexose monosaccharide glucose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
10830	regulation of myotube differentiation	P	Any process that modulates the frequency, rate or extent of myotube differentiation. Myotube differentiation is the process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse.
10831	positive regulation of myotube differentiation	P	Any process that increases the frequency, rate or extent of myotube differentiation. Myotube differentiation is the process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse.
10832	negative regulation of myotube differentiation	P	Any process that decreases the frequency, rate or extent of myotube differentiation. Myotube differentiation is the process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse.
10833	telomere maintenance via telomere lengthening	P	Any process that contributes to the maintenance of proper telomeric length and structure by affecting and monitoring the activity of telomeric proteins and lengthening the telomeric DNA.
10835	regulation of protein ADP-ribosylation	P	Any process that modulates the frequency, rate or extent of protein ADP-ribosylation. Protein ADP-ribosylation is the transfer, from NAD, of ADP-ribose to protein amino acids.
10836	negative regulation of protein ADP-ribosylation	P	Any process that decreases the frequency, rate or extent of protein ADP-ribosylation. Protein ADP-ribosylation is the transfer, from NAD, of ADP-ribose to protein amino acids.
10837	regulation of keratinocyte proliferation	P	Any process that modulates the rate, frequency or extent of keratinocyte proliferation. Keratinocyte proliferation is the multiplication or reproduction of keratinocytes, resulting in the expansion of a cell population.
10838	positive regulation of keratinocyte proliferation	P	Any process that increases the rate, frequency or extent of keratinocyte proliferation. Keratinocyte proliferation is the multiplication or reproduction of keratinocytes, resulting in the expansion of a cell population.
10839	negative regulation of keratinocyte proliferation	P	Any process that decreases the rate, frequency or extent of keratinocyte proliferation. Keratinocyte proliferation is the multiplication or reproduction of keratinocytes, resulting in the expansion of a cell population.
10840	regulation of circadian sleep/wake cycle, wakefulness	P	Any process that modulates the rate, frequency, or extent of the wakeful phase of the circadian sleep/wake cycle. The wakeful phase is the part of the circadian sleep/wake cycle where the organism is not asleep.
10841	positive regulation of circadian sleep/wake cycle, wakefulness	P	Any process that increases the frequency, or extent of the wakeful phase of the circadian sleep/wake cycle. The wakeful phase is the part of the circadian sleep/wake cycle where the organism is not asleep.
10842	retina layer formation	P	The process in which the vertebrate retina is organized into three laminae: the outer nuclear layer (ONL), which contains photoreceptor nuclei; the inner nuclear layer (INL), which contains amacrine, bipolar and horizontal cells; and the retinal ganglion cell (RGC) layer. Between the inner and outer nuclear layers, the outer plexiform layer (OPL) contains connections between the photoreceptors and bipolar and horizontal cells. The inner plexiform layer (IPL) is positioned between the INL and the ganglion cell layer and contains the dendrites of RGCs and processes of bipolar and amacrine cells. Spanning all layers of the retina are the radially oriented Mueller glia.
10844	recombination hotspot binding	F	Interacting selectively and non-covalently with a region in a genome which promotes recombination.
10845	positive regulation of reciprocal meiotic recombination	P	Any process that increases the frequency, rate or extent of recombination during meiosis. Reciprocal meiotic recombination is the cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate.
10846	activation of reciprocal meiotic recombination	P	Any process that starts the inactive process of reciprocal meiotic recombination. Reciprocal meiotic recombination is the cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate.
10847	regulation of chromatin assembly	P	Any process the modulates the frequency, rate or extent of chromatin assembly. Chromatin assembly is the assembly of DNA, histone proteins, and other associated proteins into chromatin structure, beginning with the formation of the basic unit, the nucleosome, followed by organization of the nucleosomes into higher order structures, ultimately giving rise to a complex organization of specific domains within the nucleus.
10848	regulation of chromatin disassembly	P	Any process that modulates the frequency, rate or extent of chromatin disassembly. Chromatin disassembly is the controlled breakdown of chromatin from a higher order structure into its simpler subcomponents, DNA, histones, and other proteins.
10849	regulation of proton-transporting ATPase activity, rotational mechanism	P	Any process that modulates the rate of ATP hydrolysis by an ATPase. Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out), by a rotational mechanism.
10850	regulation of blood pressure by chemoreceptor signaling pathway	P	A series of reactions within the cell that occur as a result of a single trigger reaction or compound interacting with a chemoreceptor resulting in a modulation of the force with which blood travels through the circulatory system. Chemoreceptors respond to oxygen, carbon dioxide and hydrogen ions.
10851	cyclase regulator activity	F	Modulates the activity of an enzyme that catalyzes a ring closure reaction.
10852	cyclase inhibitor activity	F	Decreases the activity of an enzyme that catalyzes a ring closure reaction.
10853	cyclase activator activity	F	Increases the activity of an enzyme that catalyzes a ring closure reaction.
10854	adenylate cyclase regulator activity	F	Modulates the activity of the enzyme that catalyzes the reaction: ATP = 3',5'-cyclic AMP + diphosphate.
10855	adenylate cyclase inhibitor activity	F	Decreases the activity of the enzyme that catalyzes the reaction: ATP = 3',5'-cyclic AMP + diphosphate.
10856	adenylate cyclase activator activity	F	Increases the activity of the enzyme that catalyzes the reaction: ATP = 3',5'-cyclic AMP + diphosphate.
10857	calcium-dependent protein kinase activity	F	Catalysis of the reaction: a protein + ATP = a phosphoprotein + ADP. This reaction requires the presence of calcium.
10858	calcium-dependent protein kinase regulator activity	F	Modulates the activity of a calcium-dependent protein kinase, an enzyme which phosphorylates a protein in a calcium-dependent manner.
10859	calcium-dependent cysteine-type endopeptidase inhibitor activity	F	Stops, prevents or reduces the activity of a calcium-dependent cysteine-type endopeptidase, any enzyme that hydrolyzes peptide bonds in polypeptides by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile in a calcium-dependent manner.
10861	thyroid hormone receptor activator activity	F	A receptor activator activity that binds to, thyroid hormone receptor in a ligand-dependent manner and enhances ligand-induced transcriptional activity of the receptor.
10862	positive regulation of pathway-restricted SMAD protein phosphorylation	P	Any process that increases the rate, frequency or extent of pathway-restricted SMAD protein phosphorylation. Pathway-restricted SMAD proteins and common-partner SMAD proteins are involved in the transforming growth factor beta receptor signaling pathways.
10863	positive regulation of phospholipase C activity	P	Any process that increases the rate of phospholipase C activity.
10864	positive regulation of protein histidine kinase activity	P	Any process that increases the frequency, rate or extent of protein histidine kinase activity.
10865	stipule development	P	The process whose specific outcome is the progression of the stipule over time, from its formation to the mature structure. A stipule is one of (usually) a pair of appendages at the bases of leaves in many broad-leaved angiosperms.
10866	regulation of triglyceride biosynthetic process	P	Any process that modulates the rate, frequency, or extent of triglyceride biosynthesis. Triglyceride biosynthesis is the collection of chemical reactions and pathways resulting in the formation of triglyceride, any triester of glycerol.
10867	positive regulation of triglyceride biosynthetic process	P	Any process that increases the rate, frequency, or extent of triglyceride biosynthesis. Triglyceride biosynthesis is the collection of chemical reactions and pathways resulting in the formation of triglyceride, any triester of glycerol.
10868	negative regulation of triglyceride biosynthetic process	P	Any process that decreases the rate, frequency, or extent of triglyceride biosynthesis. Triglyceride biosynthesis is the collection of chemical reactions and pathways resulting in the formation of triglyceride, any triester of glycerol.
10869	regulation of receptor biosynthetic process	P	Any process that modulates the frequency or rate of receptor biosynthesis. Receptor biosynthesis is the collection of chemical reactions and pathways resulting in the formation of a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.
10870	positive regulation of receptor biosynthetic process	P	Any process that increases the frequency or rate of receptor biosynthesis. Receptor biosynthesis is the collection of chemical reactions and pathways resulting in the formation of a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.
10871	negative regulation of receptor biosynthetic process	P	Any process that decreases the frequency or rate of receptor biosynthesis. Receptor biosynthesis is the collection of chemical reactions and pathways resulting in the formation of a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.
10872	regulation of cholesterol esterification	P	Any process that modulates the frequency, rate or extent of cholesterol esterification. Cholesterol esterification is the lipid modification process in which a sterol ester is formed by the combination of a carboxylic acid (often a fatty acid) and cholesterol. In the blood this process is associated with the conversion of free cholesterol into cholesteryl ester, which is then sequestered into the core of a lipoprotein particle.
10873	positive regulation of cholesterol esterification	P	Any process that increases the frequency, rate or extent of cholesterol esterification. Cholesterol esterification is the lipid modification process in which a sterol ester is formed by the combination of a carboxylic acid (often a fatty acid) and cholesterol. In the blood this process is associated with the conversion of free cholesterol into cholesteryl ester, which is then sequestered into the core of a lipoprotein particle.
10874	regulation of cholesterol efflux	P	Any process that modulates the frequency, rate or extent of cholesterol efflux. Cholesterol efflux is the directed movement of cholesterol, cholest-5-en-3-beta-ol, out of a cell or organelle.
10875	positive regulation of cholesterol efflux	P	Any process that increases the frequency, rate or extent of cholesterol efflux. Cholesterol efflux is the directed movement of cholesterol, cholest-5-en-3-beta-ol, out of a cell or organelle.
10876	lipid localization	P	Any process in which a lipid is transported to, or maintained in, a specific location.
10877	lipid transport involved in lipid storage	P	The directed movement of lipids into cells that is part of their accumulation and maintenance.
10878	cholesterol storage	P	The accumulation and maintenance in cells or tissues of cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones.
10879	cholesterol transport involved in cholesterol storage	P	The directed movement of cholesterol into cells that is part of their accumulation and maintenance.
10880	regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum	P	Any process that modulates the rate, frequency or extent of release of sequestered calcium ion into cytosol by the sarcoplasmic reticulum, the process in which the release of sequestered calcium ion by sarcoplasmic reticulum into cytosol occurs via calcium release channels.
10881	regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion	P	Any process that modulates the frequency, rate or extent of cardiac muscle contraction via the regulation of the release of sequestered calcium ion by sarcoplasmic reticulum into cytosol. The sarcoplasmic reticulum is the endoplasmic reticulum of striated muscle, specialised for the sequestration of calcium ions that are released upon receipt of a signal relayed by the T tubules from the neuromuscular junction.
10882	regulation of cardiac muscle contraction by calcium ion signaling	P	Any process that modulates the frequency, rate or extent of cardiac muscle contraction by changing the calcium ion signals that trigger contraction.
10883	regulation of lipid storage	P	Any process that modulates the rate, frequency or extent of lipid storage. Lipid storage is the accumulation and maintenance in cells or tissues of lipids, compounds soluble in organic solvents but insoluble or sparingly soluble in aqueous solvents. Lipid reserves can be accumulated during early developmental stages for mobilization and utilization at later stages of development.
10884	positive regulation of lipid storage	P	Any process that increases the rate, frequency or extent of lipid storage. Lipid storage is the accumulation and maintenance in cells or tissues of lipids, compounds soluble in organic solvents but insoluble or sparingly soluble in aqueous solvents. Lipid reserves can be accumulated during early developmental stages for mobilization and utilization at later stages of development.
10885	regulation of cholesterol storage	P	Any process that modulates the rate or extent of cholesterol storage. Cholesterol storage is the accumulation and maintenance in cells or tissues of cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones.
10886	positive regulation of cholesterol storage	P	Any process that increases the rate or extent of cholesterol storage. Cholesterol storage is the accumulation and maintenance in cells or tissues of cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones.
10887	negative regulation of cholesterol storage	P	Any process that decreases the rate or extent of cholesterol storage. Cholesterol storage is the accumulation and maintenance in cells or tissues of cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones.
10888	negative regulation of lipid storage	P	Any process that decreases the rate, frequency or extent of lipid storage. Lipid storage is the accumulation and maintenance in cells or tissues of lipids, compounds soluble in organic solvents but insoluble or sparingly soluble in aqueous solvents. Lipid reserves can be accumulated during early developmental stages for mobilization and utilization at later stages of development.
10889	regulation of sequestering of triglyceride	P	Any process that modulates the rate, frequency or extent of sequestering of triglyceride. Triglyceride sequestration is the process of binding or confining any triester of glycerol such that it is separated from other components of a biological system.
10890	positive regulation of sequestering of triglyceride	P	Any process that increases the rate, frequency or extent of sequestering of triglyceride. Triglyceride sequestration is the process of binding or confining any triester of glycerol such that it is separated from other components of a biological system.
10891	negative regulation of sequestering of triglyceride	P	Any process that decreases the rate, frequency or extent of sequestering of triglyceride. Triglyceride sequestration is the process of binding or confining any triester of glycerol such that it is separated from other components of a biological system.
10892	positive regulation of mitochondrial translation in response to stress	P	Any process that activates or increases the frequency, rate or extent of mitochondrial translation as a result of a stimulus indicating the organism is under stress.
10893	positive regulation of steroid biosynthetic process	P	Any process that increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus.
10894	negative regulation of steroid biosynthetic process	P	Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus.
10895	negative regulation of ergosterol biosynthetic process	P	Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of ergosterol.
10896	regulation of triglyceride catabolic process	P	Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of triglyceride.
10897	negative regulation of triglyceride catabolic process	P	Any process that decreases the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of triglyceride.
10898	positive regulation of triglyceride catabolic process	P	Any process that increases the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of triglyceride.
10899	regulation of phosphatidylcholine catabolic process	P	Any process that modulates the rate, frequency or extent of phosphatidylcholine catabolism. Phosphatidylcholine catabolic processes are the chemical reactions and pathways resulting in the breakdown of phosphatidylcholines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of choline.
10900	negative regulation of phosphatidylcholine catabolic process	P	Any process that decreases the rate, frequency or extent of phosphatidylcholine catabolism. Phosphatidylcholine catabolic processes are the chemical reactions and pathways resulting in the breakdown of phosphatidylcholines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of choline.
10901	regulation of very-low-density lipoprotein particle remodeling	P	Any process that modulates the rate, frequency or extent of very-low-density lipoprotein particle remodeling. Very-low-density lipoprotein particle remodeling is the acquisition, loss or modification of a protein or lipid within a very-low-density lipoprotein particle, including the hydrolysis of triglyceride by hepatic lipase or lipoprotein lipase and the subsequent loss of free fatty acid.
10902	positive regulation of very-low-density lipoprotein particle remodeling	P	Any process that increases the rate, frequency or extent of very-low-density lipoprotein particle remodeling. Very-low-density lipoprotein particle remodeling is the acquisition, loss or modification of a protein or lipid within a very-low-density lipoprotein particle, including the hydrolysis of triglyceride by hepatic lipase or lipoprotein lipase and the subsequent loss of free fatty acid.
10903	negative regulation of very-low-density lipoprotein particle remodeling	P	Any process that decreases the rate, frequency or extent of very-low-density lipoprotein particle remodeling. Very-low-density lipoprotein particle remodeling is the acquisition, loss or modification of a protein or lipid within a very-low-density lipoprotein particle, including the hydrolysis of triglyceride by hepatic lipase or lipoprotein lipase and the subsequent loss of free fatty acid.
10904	regulation of UDP-glucose catabolic process	P	Any process that modulates the rate, frequency or extent of UDP-glucose catabolism. UDP-glucose catabolic processes are the chemical reactions and pathways resulting in the breakdown of UDP-glucose, uridinediphosphoglucose, a substance composed of glucose in glycosidic linkage with uridine diphosphate.
10905	negative regulation of UDP-glucose catabolic process	P	Any process that decreases the rate, frequency or extent of UDP-glucose catabolism. UDP-glucose catabolic processes are the chemical reactions and pathways resulting in the breakdown of UDP-glucose, uridinediphosphoglucose, a substance composed of glucose in glycosidic linkage with uridine diphosphate.
10906	regulation of glucose metabolic process	P	Any process that modulates the rate, frequency or extent of glucose metabolism. Glucose metabolic processes are the chemical reactions and pathways involving glucose, the aldohexose gluco-hexose.
10907	positive regulation of glucose metabolic process	P	Any process that increases the rate, frequency or extent of glucose metabolism. Glucose metabolic processes are the chemical reactions and pathways involving glucose, the aldohexose gluco-hexose.
10908	regulation of heparan sulfate proteoglycan biosynthetic process	P	Any process that modulates the rate, frequency or extent of heparan sulfate proteoglycan biosynthesis. Heparan sulfate proteoglycan biosynthetic processes are the chemical reactions and pathways resulting in the formation of the heparan sulfate proteoglycan, a glycosaminoglycan with repeat unit consisting of alternating alpha-(1->4)-linked hexuronic acid and glucosamine residues.
10909	positive regulation of heparan sulfate proteoglycan biosynthetic process	P	Any process that increases the rate, frequency or extent of heparan sulfate proteoglycan biosynthesis. Heparan sulfate proteoglycan biosynthetic processes are the chemical reactions and pathways resulting in the formation of the heparan sulfate proteoglycan, a glycosaminoglycan with repeat unit consisting of alternating alpha-(1->4)-linked hexuronic acid and glucosamine residues.
10910	positive regulation of heparan sulfate proteoglycan biosynthesis by positive regulation of epimerase activity	P	Any process that increases the rate, frequency or extent of heparan sulfate proteoglycan biosynthesis by an increase in epimerase activity. This epimerase activity catalyzes the reaction that converts D-glucuronate into its diastereoisomer in heparan sulfate.
10911	regulation of isomerase activity	P	Any process that modulates the activity of an isomerase. An isomerase catalyzes the geometric or structural changes within one molecule. Isomerase is the systematic name for any enzyme of EC class 5.
10912	positive regulation of isomerase activity	P	Any process that increases the activity of an isomerase. An isomerase catalyzes the geometric or structural changes within one molecule. Isomerase is the systematic name for any enzyme of EC class 5.
10913	regulation of sterigmatocystin biosynthetic process	P	Any process that modulates the rate, frequency, or extent of sterigmatocystin biosynthesis. Sterigmatocystin biosynthetic processes are the chemical reactions and pathways resulting in the formation of sterigmatocystin, a carcinogenic mycotoxin produced in high yields by strains of the common molds.
10914	positive regulation of sterigmatocystin biosynthetic process	P	Any process that increases the rate, frequency, or extent of sterigmatocystin biosynthesis. Sterigmatocystin biosynthetic processes are the chemical reactions and pathways resulting in the formation of sterigmatocystin, a carcinogenic mycotoxin produced in high yields by strains of the common molds.
10915	regulation of very-low-density lipoprotein particle clearance	P	Any process that modulates the rate, frequency or extent of very-low-density lipoprotein particle clearance. Very-low-density lipoprotein particle clearance is the process in which a very-low-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.
10916	negative regulation of very-low-density lipoprotein particle clearance	P	Any process that decreases the rate, frequency or extent of very-low-density lipoprotein particle clearance. Very-low-density lipoprotein particle clearance is the process in which a very-low-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.
10917	negative regulation of mitochondrial membrane potential	P	Any process that stops, prevents, or reduces the frequency, rate or extent of establishment or extent of a mitochondrial membrane potential, the electric potential existing across any mitochondrial membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane.
10918	positive regulation of mitochondrial membrane potential	P	Any process that activates or increases the frequency, rate or extent of establishment or extent of a mitochondrial membrane potential, the electric potential existing across any mitochondrial membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane.
10919	regulation of inositol phosphate biosynthetic process	P	Any process that modulates the rate, frequency or extent of inositol phosphate biosynthesis. Inositol phosphate biosynthetic processes are the chemical reactions and pathways resulting in the formation of an inositol phosphate, 1,2,3,4,5,6-cyclohexanehexol, with one or more phosphate groups attached.
10920	negative regulation of inositol phosphate biosynthetic process	P	Any process that decreases the rate, frequency or extent of inositol phosphate biosynthesis. Inositol phosphate biosynthetic processes are the chemical reactions and pathways resulting in the formation of an inositol phosphate, 1,2,3,4,5,6-cyclohexanehexol, with one or more phosphate groups attached.
10921	regulation of phosphatase activity	P	Any process that modulates the rate or frequency of phosphatase activity. Phosphatases catalyze the hydrolysis of phosphoric monoesters, releasing inorganic phosphate.
10922	positive regulation of phosphatase activity	P	Any process that increases the rate or frequency of phosphatase activity. Phosphatases catalyze the hydrolysis of phosphoric monoesters, releasing inorganic phosphate.
10923	negative regulation of phosphatase activity	P	Any process that decreases the rate or frequency of phosphatase activity. Phosphatases catalyze the hydrolysis of phosphoric monoesters, releasing inorganic phosphate.
10924	regulation of inositol-polyphosphate 5-phosphatase activity	P	Any process that modulates the rate or frequency of inositol-polyphosphate 5-phosphatase activity, the catalysis of the reactions: D-myo-inositol 1,4,5-trisphosphate + H2O = myo-inositol 1,4-bisphosphate + phosphate, and 1D-myo-inositol 1,3,4,5-tetrakisphosphate + H2O = 1D-myo-inositol 1,3,4-trisphosphate + phosphate.
10925	positive regulation of inositol-polyphosphate 5-phosphatase activity	P	Any process that increases the rate or frequency of inositol-polyphosphate 5-phosphatase activity, the catalysis of the reactions: D-myo-inositol 1,4,5-trisphosphate + H2O = myo-inositol 1,4-bisphosphate + phosphate, and 1D-myo-inositol 1,3,4,5-tetrakisphosphate + H2O = 1D-myo-inositol 1,3,4-trisphosphate + phosphate.
10927	cellular component assembly involved in morphogenesis	P	The cellular component assembly that is part of the initial shaping of the component during its developmental progression.
10928	regulation of auxin mediated signaling pathway	P	Any process that modulates the rate, frequency or extent of auxin mediated signaling pathway. Auxin mediated signaling pathway is the series of molecular signals generated in response to detection of auxin.
10929	positive regulation of auxin mediated signaling pathway	P	Any process that increases the rate, frequency or extent of auxin mediated signaling pathway. Auxin mediated signaling pathway is the series of molecular signals generated in response to detection of auxin.
10930	negative regulation of auxin mediated signaling pathway	P	Any process that decreases the rate, frequency or extent of auxin mediated signaling pathway. Auxin mediated signaling pathway is the series of molecular signals generated in response to detection of auxin.
10931	macrophage tolerance induction	P	A process involving any mechanism for tolerance induction in macrophages.
10932	regulation of macrophage tolerance induction	P	Any process that modulates the frequency, rate, or extent of macrophage tolerance induction.
10933	positive regulation of macrophage tolerance induction	P	Any process that increases the frequency, rate, or extent of B cell tolerance induction.
10934	macrophage cytokine production	P	The appearance of a macrophage cytokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
10935	regulation of macrophage cytokine production	P	Any process that modulates the rate, frequency or extent of macrophage cytokine production. Macrophage cytokine production is the appearance of a chemokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
10936	negative regulation of macrophage cytokine production	P	Any process that decreases the rate, frequency or extent of macrophage cytokine production. Macrophage cytokine production is the appearance of a chemokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
10937	regulation of cytoplasmic microtubule depolymerization	P	Any process that modulates the frequency, rate or extent of cytoplasmic microtubule depolymerization.
10938	cytoplasmic microtubule depolymerization	P	The removal of tubulin heterodimers from one or both ends of a cytoplasmic microtubule.
10939	regulation of necrotic cell death	P	Any process that modulates the rate, frequency or extent of necrotic cell death. Necrotic cell death is a cell death process that is morphologically characterized by a gain in cell volume (oncosis), swelling of organelles, plasma membrane rupture and subsequent loss of intracellular contents.
10940	positive regulation of necrotic cell death	P	Any process that increases the rate, frequency or extent of necrotic cell death. Necrotic cell death is a cell death process that is morphologically characterized by a gain in cell volume (oncosis), swelling of organelles, plasma membrane rupture and subsequent loss of intracellular contents.
10941	regulation of cell death	P	Any process that modulates the rate or frequency of cell death. Cell death is the specific activation or halting of processes within a cell so that its vital functions markedly cease, rather than simply deteriorating gradually over time, which culminates in cell death.
10942	positive regulation of cell death	P	Any process that increases the rate or frequency of cell death. Cell death is the specific activation or halting of processes within a cell so that its vital functions markedly cease, rather than simply deteriorating gradually over time, which culminates in cell death.
10943	NADPH pyrophosphatase activity	F	Catalysis of the reaction: NADPH + H2O = NMNH + ADP.
10944	negative regulation of transcription by competitive promoter binding	P	Any process that stops, prevents, or reduces the frequency, rate or extent of DNA-dependent transcription using a mechanism that involves direct competition for interaction with a promoter binding site.
10945	CoA pyrophosphatase activity	F	Catalysis of the reaction: coenzyme A + H2O = 3',5'-ADP + 4'-phosphopantetheine.
10946	regulation of meiotic joint molecule formation	P	Any process that modulates the frequency, rate or extent of meiotic joint molecule formation. Meiotic joint molecule formation is the conversion of the paired broken DNA and homologous duplex DNA into a four-stranded branched intermediate, known as a joint molecule, formed during meiotic recombination.
10947	negative regulation of meiotic joint molecule formation	P	Any process that decreases the frequency, rate or extent of meiotic joint molecule formation. Meiotic joint molecule formation is the conversion of the paired broken DNA and homologous duplex DNA into a four-stranded branched intermediate, known as a joint molecule, formed during meiotic recombination.
10948	negative regulation of cell cycle process	P	Any process that decreases the rate, frequency or extent of a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events.
10949	negative regulation of intestinal phytosterol absorption	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of phytosterols into the blood by absorption from the small intestine.
10950	positive regulation of endopeptidase activity	P	Any process that increases the frequency, rate or extent of endopeptidase activity, the endohydrolysis of peptide bonds within proteins.
10951	negative regulation of endopeptidase activity	P	Any process that decreases the frequency, rate or extent of endopeptidase activity, the endohydrolysis of peptide bonds within proteins.
10952	positive regulation of peptidase activity	P	Any process that increases the frequency, rate or extent of peptidase activity, the hydrolysis of peptide bonds within proteins.
10954	positive regulation of protein processing	P	Any process that increases the rate, frequency or extent of protein maturation by peptide bond cleavage.
10955	negative regulation of protein processing	P	Any process that decreases the rate, frequency or extent of protein maturation by peptide bond cleavage.
10956	negative regulation of calcidiol 1-monooxygenase activity	P	Any process that decreases the rate, frequency or extent of calcidiol 1-monooxygenase activity. Calcidiol 1-monooxygenase activity is the catalysis of the reaction: calcidiol + NADPH + H+ + O2 = calcitriol + NADP+ + H2O.
10957	negative regulation of vitamin D biosynthetic process	P	Any process that decreases the rate, frequency or extent of a vitamin D biosynthetic process. Vitamin D biosynthesis is the chemical reactions and pathways resulting in the formation of vitamin D, any of a group of related, fat-soluble compounds that are derived from delta-5,7 steroids and play a central role in calcium metabolism. Specific forms of vitamin D include calciferol (ergocalciferol; vitamin D2) and cholecalciferol (calciol; vitamin D3).
10958	regulation of amino acid import	P	Any process that modulates the frequency, rate or extent of amino acid import. Amino acid import is the directed movement of amino acids into a cell or organelle.
10959	regulation of metal ion transport	P	Any process that modulates the frequency, rate, or extent of metal ion transport. Metal ion transport is the directed movement of metal ions, any metal ion with an electric charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
10960	magnesium ion homeostasis	P	Any process involved in the maintenance of an internal steady state of magnesium ions within an organism or cell.
10961	cellular magnesium ion homeostasis	P	Any process involved in the maintenance of an internal steady state of magnesium ions at the level of a cell.
10962	regulation of glucan biosynthetic process	P	Any process that modulates the rate, frequency, or extent of glucan biosynthesis. Glucan biosynthetic processes are the chemical reactions and pathways resulting in the formation of glucans, polysaccharides consisting only of glucose residues.
10963	regulation of L-arginine import	P	Any process that modulates the frequency, rate or extent of L-arginine import. L-arginine import is the directed movement of L-arginine, the L-enantiomer of 2-amino-5-guanidinopentanoic acid, into a cell or organelle.
10964	regulation of chromatin silencing by small RNA	P	Any process that modulates the frequency, rate or extent of chromatin silencing by small RNA. Chromatin silencing by small RNA is the repression of transcription by conversion of large regions of DNA into heterochromatin, directed by small RNAs sharing sequence identity to the repressed region.
10965	regulation of mitotic sister chromatid separation	P	Any process that modulates the frequency, rate or extent of mitotic sister chromatid separation. Mitotic sister chromatid separation is the process in which sister chromatids are physically detached from each other during mitosis.
10966	regulation of phosphate transport	P	Any process that modulates the frequency, rate or extent of phosphate transport. Phosphate transport is the directed movement of phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
10967	regulation of polyamine biosynthetic process	P	Any process that modulates the frequency, rate or extent of polyamine biosynthesis. Polyamine biosynthesis is the chemical reactions and pathways resulting in the formation of polyamines, any organic compound containing two or more amino groups.
10968	regulation of microtubule nucleation	P	Any process that modulates the rate, frequency or extent of microtubule nucleation. Microtubule nucleation is the 'de novo' formation of a microtubule, in which tubulin heterodimers form metastable oligomeric aggregates, some of which go on to support formation of a complete microtubule. Microtubule nucleation usually occurs from a specific site within a cell.
10969	regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion	P	Any process that modulates the frequency, rate or extent of pheromone-dependent signal transduction during conjugation with cellular fusion, a signal transduction process resulting in the relay, amplification or dampening of a signal generated in response to pheromone exposure in organisms that undergo conjugation with cellular fusion.
10970	transport along microtubule	P	The movement of organelles or other particles from one location in the cell to another along microtubules, driven by motor activity.
10971	positive regulation of G2/M transition of mitotic cell cycle	P	Any process that increases the rate or extent of progression from G2 phase to M phase of the mitotic cell cycle.
10972	negative regulation of G2/M transition of mitotic cell cycle	P	Any cell cycle regulatory process that decreases the rate or extent of progression of a cell from G2 to M phase of the mitotic cell cycle.
10973	positive regulation of barrier septum assembly	P	Any process that increases the frequency, rate or extent of barrier septum formation. Barrier septum formation is the assembly and arrangement of a septum that spans the plasma membrane interface between progeny cells following cytokinesis.
10974	negative regulation of barrier septum assembly	P	Any process that decreases the frequency, rate or extent of barrier septum formation. Barrier septum formation is he assembly and arrangement of a septum that spans the plasma membrane interface between progeny cells following cytokinesis.
10975	regulation of neuron projection development	P	Any process that modulates the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites).
10976	positive regulation of neuron projection development	P	Any process that increases the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites).
10977	negative regulation of neuron projection development	P	Any process that decreases the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites).
10978	gene silencing involved in chronological cell aging	P	Any transcriptional or post-transcriptional process, arising in non-dividing cells as they age, carried out at the cellular level that results in long-term gene inactivation.
10979	regulation of vitamin D 24-hydroxylase activity	P	Any process that modulates the rate, frequency or extent of vitamin D 24-hydroxylase activity. Vitamin D 24-hydroxylase activity catalyzes the hydroxylation of C-24 of any form of vitamin D.
10980	positive regulation of vitamin D 24-hydroxylase activity	P	Any process that increases the rate, frequency or extent of vitamin D 24-hydroxylase activity. Vitamin D 24-hydroxylase activity catalyzes the hydroxylation of C-24 of any form of vitamin D.
10981	regulation of cell wall macromolecule metabolic process	P	Any process that modulates the rate, frequency or extent of cell wall macromolecule metabolism. Cell wall macromolecule metabolic processes are the chemical reactions and pathways involving macromolecules forming, or destined to form, part of the cell wall. A cell wall is a rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal and most prokaryotic cells, maintaining their shape and protecting them from osmotic lysis.
10982	regulation of high-density lipoprotein particle clearance	P	Any process that modulates the rate, frequency or extent of high-density lipoprotein particle clearance. High-density lipoprotein particle clearance is the process in which a high-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.
10983	positive regulation of high-density lipoprotein particle clearance	P	Any process that increases the rate, frequency or extent of high-density lipoprotein particle clearance. High-density lipoprotein particle clearance is the process in which a high-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.
10984	regulation of lipoprotein particle clearance	P	Any process that modulates the rate, frequency, or extent of lipoprotein particle clearance. Lipoprotein particle clearance is the process in which a lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.
10985	negative regulation of lipoprotein particle clearance	P	Any process that decreases the rate, frequency, or extent of lipoprotein particle clearance. Lipoprotein particle clearance is the process in which a lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.
10986	positive regulation of lipoprotein particle clearance	P	Any process that increases the rate, frequency, or extent of lipoprotein particle clearance. Lipoprotein particle clearance is the process in which a lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.
10987	negative regulation of high-density lipoprotein particle clearance	P	Any process that decreases the rate, frequency or extent of high-density lipoprotein particle clearance. High-density lipoprotein particle clearance is the process in which a high-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.
10988	regulation of low-density lipoprotein particle clearance	P	Any process that modulates the rate, frequency or extent of low-density lipoprotein particle clearance. Low-density lipoprotein particle clearance is the process in which a low-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.
10989	negative regulation of low-density lipoprotein particle clearance	P	Any process that decreases the rate, frequency or extent of low-density lipoprotein particle clearance. Low-density lipoprotein particle clearance is the process in which a low-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.
10990	regulation of SMAD protein complex assembly	P	Any process that modulates the rate, frequency, or extent of SMAD protein complex assembly. SMAD protein complex assembly is the aggregation, arrangement and bonding together of a set of components to form a protein complex that contains SMAD proteins.
10991	negative regulation of SMAD protein complex assembly	P	Any process that decreases the rate, frequency, or extent of SMAD protein complex assembly. SMAD protein complex assembly is the aggregation, arrangement and bonding together of a set of components to form a protein complex that contains SMAD proteins.
10992	ubiquitin homeostasis	P	Any process involved in the maintenance of an internal steady state of ubiquitin monomers and free ubiquitin chains at the level of the cell.
10993	regulation of ubiquitin homeostasis	P	Any process that modulates the rate, frequency, or extent of ubiquitin homeostasis. Ubiquitin homeostasis is any process involved in the maintenance of an internal steady state of ubiquitin monomers and free ubiquitin chains at the level of the cell.
10994	free ubiquitin chain polymerization	P	The process of creating free ubiquitin chains, compounds composed of a large number of ubiquitin monomers. These chains are not conjugated to a protein.
10995	free ubiquitin chain depolymerization	P	The process in which free ubiquitin chains, compounds composed of a large number of ubiquitin monomers, are broken down.
10996	response to auditory stimulus	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an auditory stimulus.
10997	anaphase-promoting complex binding	F	Interacting selectively and non-covalently with an anaphase-promoting complex. A ubiquitin ligase complex that degrades mitotic cyclins and anaphase inhibitory protein, thereby triggering sister chromatid separation and exit from mitosis.
10998	regulation of translational initiation by eIF2 alpha phosphorylation	P	Any process that modulates the frequency, rate or extent of translation initiation in response to stress by the phosphorylation of eIF2 alpha.
10999	regulation of eIF2 alpha phosphorylation by heme	P	Any process that modulates the rate, frequency, or extent of eIF2 alpha phosphorylation as a result of heme levels.
11000	replication fork arrest at mating type locus	P	A process that impedes the progress of the DNA replication fork at natural replication fork pausing sites within the mating type locus.
12501	programmed cell death	P	A process which begins when a cell receives an internal or external signal and activates a series of biochemical events (signaling pathway). The process ends with the death of the cell.
12502	induction of programmed cell death	P	A process which directly activates any of the steps required for programmed cell death.
12505	endomembrane system	C	A collection of membranous structures involved in transport within the cell. The main components of the endomembrane system are endoplasmic reticulum, Golgi bodies, vesicles, cell membrane and nuclear envelope. Members of the endomembrane system pass materials through each other or though the use of vesicles.
12506	vesicle membrane	C	The lipid bilayer surrounding any membrane-bounded vesicle in the cell.
12507	ER to Golgi transport vesicle membrane	C	The lipid bilayer surrounding a vesicle transporting substances from the endoplasmic reticulum to the Golgi.
12508	Golgi to ER transport vesicle membrane	C	The lipid bilayer surrounding a vesicle transporting substances from the Golgi to the ER.
12509	inter-Golgi transport vesicle membrane	C	The lipid bilayer surrounding a vesicle transporting substances within the Golgi.
12510	trans-Golgi network transport vesicle membrane	C	The lipid bilayer surrounding a vesicle transporting substances between the trans-Golgi network and other parts of the cell.
12511	monolayer-surrounded lipid storage body	C	A subcellular organelle of plant cells surrounded by 'half-unit' or a monolayer membrane instead of the more usual bilayer. The storage body has a droplet of triglyceride surrounded by a monolayer of phospholipids, interacting with the triglycerides and the hydrophilic head groups facing the cytosol, and containing major protein components called oleosins.
14001	sclerenchyma cell differentiation	P	The process in which a relatively unspecialized cell acquires specialized features of a sclerenchyma cell. A sclerenchyma cell is a plant cell with thick lignified walls, normally dead at maturity and specialized for structural strength. Includes fiber cells, that are greatly elongated; and sclereids, that are more isodiametric. Intermediate types exist. Cells may or may not be devoid of protoplasm at maturity. Cell form and size are variable.
14002	astrocyte development	P	The process aimed at the progression of an astrocyte over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. An astrocyte is the most abundant type of glial cell. Astrocytes provide support for neurons and regulate the environment in which they function.
14003	oligodendrocyte development	P	The process aimed at the progression of an oligodendrocyte over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. An oligodendrocyte is a type of glial cell involved in myelinating the axons in the central nervous system.
14004	microglia differentiation	P	The process in which a relatively unspecialized cell acquires specialized features of a microglial cell. Microglia are glial cells that act as the immune cells of the central nervous system. They form part of the supporting structure of this system.
14005	microglia development	P	The process aimed at the progression of a microglial cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.
14006	regulation of microglia differentiation	P	Any process that modulates the frequency, rate or extent of microglia differentiation, the process in which a relatively unspecialized cell acquires specialized features of a microglial cell.
14007	negative regulation of microglia differentiation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of microglia differentiation, the process in which a relatively unspecialized cell acquires specialized features of a microglial cell.
14008	positive regulation of microglia differentiation	P	Any process that activates, maintains or increases the frequency, rate or extent of microglia differentiation, the process in which a relatively unspecialized cell acquires specialized features of a microglial cell.
14009	glial cell proliferation	P	The multiplication or reproduction of glial cells by cell division, resulting in the expansion of their population. Glial cells exist throughout the nervous system, and include Schwann cells, astrocytes, and oligodendrocytes among others.
14010	Schwann cell proliferation	P	The multiplication or reproduction of Schwann cells, resulting in the expansion of their population. Schwann cells are a type of glial cell in the peripheral nervous system.
14011	Schwann cell proliferation involved in axon regeneration	P	The multiplication or reproduction of Schwann cells by cell division, resulting in the expansion of their population in response to an axonal lesion. The newly generated Schwann cells support subsequent axon regeneration in the peripheral nervous system.
14012	peripheral nervous system axon regeneration	P	The regrowth of axons outside the central nervous system (outside the brain and spinal cord) following an axonal injury.
14013	regulation of gliogenesis	P	Any process that modulates the frequency, rate or extent of gliogenesis, the formation of mature glia.
14014	negative regulation of gliogenesis	P	Any process that stops, prevents, or reduces the frequency, rate or extent of gliogenesis, the formation of mature glia.
14015	positive regulation of gliogenesis	P	Any process that activates or increases the frequency, rate or extent of gliogenesis, the formation of mature glia.
14016	neuroblast differentiation	P	The process in which a relatively unspecialized cell acquires specialized features of a neuroblast. There are at least four stages through which the pluripotent cells of epiblast or blastula become neuroblasts.
14017	neuroblast fate commitment	P	The process in which the developmental fate of a cell becomes restricted such that it will differentiate into a neuroblast.
14018	neuroblast fate specification	P	The process in which a cell becomes capable of differentiating autonomously into a neuroblast in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed.
14019	neuroblast development	P	The process aimed at the progression of a neuroblast over time, from initial commitment of the cell to a specific state, to the mature neuroblast. It does not include processes where the neuroblast turns into a glial cell or a neuron.
14020	primary neural tube formation	P	The formation of the neural tube from an epithelial cell sheet (the neuroepithelium or neural plate). In primary neurulation, the cells surrounding the neural plate direct the neural plate cells to proliferate, invaginate, and pinch off from the surface to form a hollow epithelial tube. Primary neurulation is the typical mechanism of formation of the anterior neural tube.
14021	secondary neural tube formation	P	The formation of the neural tube by coalescence of mesenchymal cells followed by their conversion to epithelial cells to form a solid cord that subsequently hollows out (cavitates) to create a hollow tube. Secondary neurulation is the typical mechanism of formation of the neural tube posterior to the posterior neuropore in mammals.
14022	neural plate elongation	P	The process in which the neural plate is shaped by the intrinsic movement of the epidermal and neural plate regions.
14023	neural rod formation	P	The formation of a solid rod of neurectoderm derived from the neural keel. The neural rod is roughly circular in cross section. Neural rod formation occurs during primary neurulation in teleosts.
14024	neural rod cavitation	P	The process of rod cavitation, which is the formation of a lumen in the neural rod during primary neurulation, producing the neural tube.
14025	neural keel formation	P	The formation of a thickened region of the neurectoderm that is roughly triangular in cross section. The neural keel develops from the neural plate and develops into the neural rod. Neural keel formation occurs during primary neurulation in teleosts.
14027	secondary neural tube rod cavitation	P	The process of medullary cavitation, which is the formation of a lumen in the medullary cord during secondary neurulation, producing the neural tube.
14028	notochord formation	P	The formation of the notochord from the chordamesoderm. The notochord is composed of large cells packed within a firm connective tissue sheath and is found in all chordates at the ventral surface of the neural tube. In vertebrates, the notochord contributes to the vertebral column.
14029	neural crest formation	P	The formation of the specialized region of ectoderm between the neural ectoderm (neural plate) and non-neural ectoderm. The neural crest gives rise to the neural crest cells that migrate away from this region as neural tube formation procedes.
14030	mesenchymal cell fate commitment	P	The process in which a cell becomes committed to become a mesenchymal cell.
14031	mesenchymal cell development	P	The process aimed at the progression of a mesenchymal cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell.
14032	neural crest cell development	P	The process aimed at the progression of a neural crest cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell.
14033	neural crest cell differentiation	P	The process in which a relatively unspecialized cell acquires specialized features of a neural crest cell.
14034	neural crest cell fate commitment	P	The process in which a cell becomes committed to become a neural crest cell.
14035	neural crest cell fate determination	P	The process in which a cell becomes capable of differentiating autonomously into a neural crest cell regardless of its environment; upon determination, the cell fate cannot be reversed.
14036	neural crest cell fate specification	P	The process in which a cell becomes capable of differentiating autonomously into a neural crest cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.
14037	Schwann cell differentiation	P	The process in which a relatively unspecialized cell acquires the specialized features of a Schwann cell. Schwann cells are found in the peripheral nervous system, where they insulate neurons and axons, and regulate the environment in which neurons function.
14038	regulation of Schwann cell differentiation	P	Any process that modulates the frequency, rate or extent of Schwann cell differentiation.
14039	negative regulation of Schwann cell differentiation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of Schwann cell differentiation.
14040	positive regulation of Schwann cell differentiation	P	Any process that activates or increases the frequency, rate or extent of Schwann cell differentiation.
14041	regulation of neuron maturation	P	Any process that modulates the frequency, rate or extent of neuron maturation, the process leading to the attainment of the full functional capacity of a neuron. This process is independent of morphogenetic change.
14042	positive regulation of neuron maturation	P	Any process that activates or increases the frequency, rate or extent of neuron maturation.
14043	negative regulation of neuron maturation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of neuron maturation.
14044	Schwann cell development	P	The process aimed at the progression of a Schwann cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. Schwann cells are found in the peripheral nervous system, where they insulate neurons and axons, and regulate the environment in which neurons function.
14045	establishment of endothelial blood-brain barrier	P	Establishment of the endothelial barrier between the blood and the brain. The endothelial cells in the brain capillaries are packed tightly together preventing the passage of most molecules from the blood into the brain. Only lipid soluble molecules or those that are actively transported can pass through the blood-brain barrier.
14046	dopamine secretion	P	The regulated release of dopamine by a cell. Dopamine is a catecholamine and a precursor of adrenaline and noradrenaline. It acts as a neurotransmitter in the central nervous system but it is also produced peripherally and acts as a hormone.
14047	glutamate secretion	P	The controlled release of glutamate by a cell. The glutamate is the most abundant excitatory neurotransmitter in the nervous system.
14048	regulation of glutamate secretion	P	Any process that modulates the frequency, rate or extent of the controlled release of glutamate.
14049	positive regulation of glutamate secretion	P	Any process that activates or increases the frequency, rate or extent of the controlled release of glutamate.
14050	negative regulation of glutamate secretion	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of glutamate.
14051	gamma-aminobutyric acid secretion	P	The regulated release of gamma-aminobutyric acid by a cell or a tissue. The gamma-aminobutyric acid is the principal inhibitory neurotransmitter in the brain but is also found in several extraneural tissues.
14052	regulation of gamma-aminobutyric acid secretion	P	Any process that modulates the frequency, rate or extent of the regulated release of gamma-aminobutyric acid.
14053	negative regulation of gamma-aminobutyric acid secretion	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of gamma-aminobutyric acid.
14054	positive regulation of gamma-aminobutyric acid secretion	P	Any process that activates or increases the frequency, rate or extent of the regulated release of gamma-aminobutyric acid.
14055	acetylcholine secretion, neurotransmission	P	The regulated release of acetylcholine by a cell. The acetylcholine acts as a neurotransmitter that acts in both the peripheral nervous system (PNS) and central nervous system (CNS).
14056	regulation of acetylcholine secretion, neurotransmission	P	Any process that modulates the frequency, rate or extent of the regulated release of acetylcholine.
14057	positive regulation of acetylcholine secretion, neurotransmission	P	Any process that activates or increases the frequency, rate or extent of the regulated release of acetylcholine.
14058	negative regulation of acetylcholine secretion, neurotransmission	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of acetylcholine.
14059	regulation of dopamine secretion	P	Any process that modulates the frequency, rate or extent of the regulated release of dopamine.
14060	regulation of epinephrine secretion	P	Any process that modulates the frequency, rate or extent of the regulated release of epinephrine.
14061	regulation of norepinephrine secretion	P	Any process that modulates the frequency, rate or extent of the regulated release of norepinephrine.
14062	regulation of serotonin secretion	P	Any process that modulates the frequency, rate or extent of the regulated release of serotonin.
14063	negative regulation of serotonin secretion	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of serotonin.
14064	positive regulation of serotonin secretion	P	Any process that activates or increases the frequency, rate or extent of the regulated release of serotonin.
14065	phosphatidylinositol 3-kinase signaling	P	A series of reactions within the signal-receiving cell, mediated by the intracellular phosphatidylinositol 3-kinase (PI3K). Many cell surface receptor linked signaling pathways signal through PI3K to regulate numerous cellular functions.
14066	regulation of phosphatidylinositol 3-kinase signaling	P	Any process that modulates the frequency, rate or extent of signal transduction mediated by the phosphatidylinositol 3-kinase cascade.
14067	negative regulation of phosphatidylinositol 3-kinase signaling	P	Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the phosphatidylinositol 3-kinase cascade.
14068	positive regulation of phosphatidylinositol 3-kinase signaling	P	Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the phosphatidylinositol 3-kinase cascade.
14069	postsynaptic density	C	An electron dense network of proteins within and adjacent to the postsynaptic membrane in asymetric synapses. Its major components include neurotransmitter receptors and the proteins that spatially and functionally organize them such as anchoring and scaffolding molecules, signaling enzymes and cytoskeletal components.
14070	response to organic cyclic compound	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic cyclic compound stimulus.
14071	response to cycloalkane	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cycloalkane stimulus. A cycloalkane is a cyclic saturated hydrocarbon having the general formula CnH2n.
14072	response to isoquinoline alkaloid	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an isoquinoline alkaloid stimulus. An isoquinoline alkaloid is any member of a group of compounds with the heterocyclic ring structure of benzo(c)pyridine which is a structure characteristic of the group of opium alkaloids.
14073	response to tropane	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tropane stimulus. Tropane is a nitrogenous bicyclic organic compound mainly known for a group of alkaloids derived from it (called tropane alkaloids), which include, among others, atropine and cocaine.
14074	response to purine-containing compound	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a purine-containing compound stimulus.
14075	response to amine	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amine stimulus. An amine is a compound formally derived from ammonia by replacing one, two or three hydrogen atoms by hydrocarbyl groups.
14076	response to fluoxetine	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fluoxetine stimulus. Fluoxetine increases the extracellular level of the neurotransmitter serotonin by inhibiting its reuptake into the presynaptic cell, increasing the level of serotonin available to bind to the postsynaptic receptor.
14701	junctional sarcoplasmic reticulum membrane	C	The part of the sarcoplasmic reticulum membrane that contains calcium release channels, is devoted to calcium release and is juxtaposed to transverse tubule membrane. The junctional sarcoplasmic reticulum membrane consists of the junctional region of the terminal cisterna membrane.
14702	free sarcoplasmic reticulum membrane	C	The part of the sarcoplasmic reticulum membrane that contains calcium pumps and is devoted to calcium uptake. The free sarcoplasmic reticulum membrane consists of the longitudinal sarcoplasmic reticulum membrane and the non-junctional region of the terminal cisterna membrane.
14703	oscillatory muscle contraction	P	A process in which force is generated within oscillatory skeletal muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. Oscillatory muscle contraction occurs in insect wing muscles and is characterized by asynchrony between action potential and contraction and by stretch activation.
14704	intercalated disc	C	A complex cell-cell junction at which myofibrils terminate in cardiomyocytes; mediates mechanical and electrochemical integration between individual cardiomyocytes. The intercalated disc contains regions of tight mechanical attachment (fasciae adherentes and desmosomes) and electrical coupling (gap junctions) between adjacent cells.
14705	C zone	C	A region of the A band in which myosin-binding protein C is located and that can be seen by electron microscopy. This is a functional zone that also includes myosin.
14706	striated muscle tissue development	P	The process whose specific outcome is the progression of a striated muscle over time, from its formation to the mature structure. Striated muscle contain fibers that are divided by transverse bands into striations, and cardiac and skeletal muscle are types of striated muscle. Skeletal muscle myoblasts fuse to form myotubes and eventually multinucleated muscle fibers. The fusion of cardiac cells is very rare and can only form binucleate cells.
14707	branchiomeric skeletal muscle development	P	The process whose specific outcome is the progression of the branchiomeric skeletal muscle over time, from its formation to the mature structure. The branchiomeric muscle is derived from cranial mesoderm and controls facial expression, pharyngeal and laryngeal function, operating the jaw. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle. Branchiomeric muscles of mammals correspond to the gill musculature of fish.
14708	regulation of somitomeric trunk muscle development	P	Any process that modulates the frequency, rate or extent of somitomeric trunk muscle development.
14709	positive regulation of somitomeric trunk muscle development	P	Any process that activates, maintains or increases the frequency, rate or extent of somitomeric trunk muscle development. The somitomeric trunk muscle is derived from somitomeric mesoderm. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle.
14710	negative regulation of somitomeric trunk muscle development	P	Any process that stops, prevents, or reduces the frequency, rate or extent of somitomeric trunk muscle development. The somitomeric trunk muscle is derived from somitomeric mesoderm. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle.
14711	regulation of branchiomeric skeletal muscle development	P	Any process that modulates the frequency, rate or extent of branchiomeric skeletal muscle development. Branchiomeric skeletal muscle development is the process whose specific outcome is the progression of the branchiomeric skeletal muscle over time, from its formation to the mature structure.
14712	positive regulation of branchiomeric skeletal muscle development	P	Any process that activates, maintains or increases the frequency, rate or extent of branchiomeric skeletal muscle development. Branchiomeric skeletal muscle development is the process whose specific outcome is the progression of the branchiomeric skeletal muscle over time, from its formation to the mature structure.
14713	negative regulation of branchiomeric skeletal muscle development	P	Any process that stops, prevents, or reduces the frequency, rate or extent of branchiomeric skeletal muscle development. Branchiomeric skeletal muscle development is the process whose specific outcome is the progression of the branchiomeric skeletal muscle over time, from its formation to the mature structure.
14714	myoblast fate commitment in head	P	The process, taking place in the head, whereby the developmental fate of a cell becomes restricted such that it will develop into a myoblast. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.
14715	myoblast fate commitment in trunk	P	The process taking place in the trunk whereby the developmental fate of a cell becomes restricted such that it will develop into a myoblast. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.
14716	skeletal muscle satellite stem cell asymmetric division involved in skeletal muscle regeneration	P	Skeletal muscle satellite cell asymmetric division that occurs during a process in which damaged muscle tissue is being rebuilt.
14717	regulation of satellite cell activation involved in skeletal muscle regeneration	P	Any process that modulates the frequency, rate or extent of satellite cell activation. The satellite cell activation is the process that initiates satellite cell division by causing it to move from quiescence to the G1 stage of the cell cycle. The cell swells and there are a number of other small changes. The cells then start to divide. Following cell division the cells will differentiate.
14718	positive regulation of satellite cell activation involved in skeletal muscle regeneration	P	Any process that activates, maintains or increases the frequency, rate or extent of activation of satellite cell involved in skeletal muscle regeneration. The activation of satellite cell is the process that initiates satellite cell division by causing it to move from quiescence to the G1 stage of the cell cycle. The cell swells and there are a number of other small changes. The cells then start to divide. Following cell division the cells will differentiate.
14719	skeletal muscle satellite cell activation	P	The change of a skeletal muscle satellite cell from a mitotically quiescent to a mitotically active state following exposure to some activating factor such as a cellular or soluble ligand. In adult muscle, satellite cells become activated to divide and differentiate in response to muscle damage.
14720	tonic skeletal muscle contraction	P	A process in which force is generated within tonic skeletal muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The tonic skeletal muscle is characterized by long lasting contractile responses and high resistance to fatigue.
14721	twitch skeletal muscle contraction	P	A process in which force is generated within twitch skeletal muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The twitch skeletal muscle responds to neurostimulations with a contraction followed by a relaxation.
14722	regulation of skeletal muscle contraction by calcium ion signaling	P	Any process that modulates the frequency, rate or extent of skeletal muscle contraction by changing the calcium ion signals that trigger contraction.
14723	regulation of skeletal muscle contraction by modulation of calcium ion sensitivity of myofibril	P	Any process that modulates the frequency, rate or extent of skeletal muscle contraction by changing calcium ion binding affinity of the myofibril.
14724	regulation of twitch skeletal muscle contraction	P	Any process that modulates the frequency, rate or extent of twitch skeletal muscle contraction.
14725	regulation of extraocular skeletal muscle development	P	Any process that modulates the frequency, rate or extent of extraocular skeletal muscle development. Extraocular skeletal muscle development is the process whose specific outcome is the progression of the extraocular skeletal muscle over time, from its formation to the mature structure. The extraocular muscle is derived from cranial mesoderm and controls eye movements. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle.
14726	negative regulation of extraocular skeletal muscle development	P	Any process that stops, prevents, or reduces the frequency, rate or extent of extraocular skeletal muscle development. Extraocular skeletal muscle development is the process whose specific outcome is the progression of the extraocular skeletal muscle over time, from its formation to the mature structure. The extraocular muscle is derived from cranial mesoderm and controls eye movements. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle.
14727	positive regulation of extraocular skeletal muscle development	P	Any process that activates, maintains or increases the frequency, rate or extent of extraocular skeletal muscle development. Extraocular skeletal muscle development is the process whose specific outcome is the progression of the extraocular skeletal muscle over time, from its formation to the mature structure. The extraocular muscle is derived from cranial mesoderm and controls eye movements. The muscle begins its development with the differentiation of the muscle cells and ends with the mature muscle.
14728	regulation of the force of skeletal muscle contraction	P	Any process that modulates the frequency, rate or extent of the force of skeletal muscle contraction. The force of skeletal muscle contraction is produced by acto-myosin interaction processes through the formation of cross bridges.
14729	regulation of the velocity of shortening of skeletal muscle modulating contraction	P	Any process that modulates velocity of shortening of a skeletal muscle contraction. The shortening leads to reduction of the length of muscle fibers and sarcomeres.
14730	skeletal muscle regeneration at neuromuscular junction	P	The regrowth of muscle tissue to repair injured or damaged muscle fibers in the postnatal stage at the neuromuscular junction. Regeneration of neuromuscular junctions occurs in an orderly way and relies on communication between nerve and muscle. Skeletal myofibers regenerate after injury and form neuro-muscular junctions with motor axons similar to normal ones. Regenerating myofibers develop within the basal lamina sheaths (satellite cells) of original myofibers.
14731	spectrin-associated cytoskeleton	C	The part of the cytoskeleton composed of spectrin, protein 4.1 and ankyrin. Spectrin-associated cytoskeleton is associated with the plasma membrane.
14732	skeletal muscle atrophy	P	A process, occurring in skeletal muscle, that is characterized by a decrease in protein content, fiber diameter, force production and fatigue resistance in response to different conditions such as starvation, aging and disuse.
14733	regulation of skeletal muscle adaptation	P	Any process in which skeletal muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. These adaptive events occur in both muscle fibers and associated structures (motoneurons and capillaries), and they involve alterations in regulatory mechanisms, contractile properties and metabolic capacities.
14734	skeletal muscle hypertrophy	P	The enlargement or overgrowth of all or part of an organ due to an increase in size (not length) of individual muscle fibers without cell division. In the case of skeletal muscle cells this happens due to the additional synthesis of sarcomeric proteins and assembly of myofibrils.
14735	regulation of muscle atrophy	P	Any process that modulates the frequency, rate or extent of muscle atrophy.
14736	negative regulation of muscle atrophy	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of muscle atrophy.
14737	positive regulation of muscle atrophy	P	Any process that activates or increases the frequency, rate or extent of muscle atrophy.
14738	regulation of muscle hyperplasia	P	Any process that modulates the frequency, rate or extent of muscle hyperplasia.
14739	positive regulation of muscle hyperplasia	P	Any process that activates or increases the frequency, rate or extent of muscle hyperplasia.
14740	negative regulation of muscle hyperplasia	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of muscle hyperplasia.
14741	negative regulation of muscle hypertrophy	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of muscle hypertrophy.
14742	positive regulation of muscle hypertrophy	P	Any process that activates or increases the frequency, rate or extent of muscle hypertrophy.
14743	regulation of muscle hypertrophy	P	Any process that modulates the frequency, rate or extent of muscle hypertrophy.
14744	positive regulation of muscle adaptation	P	Any process that activates or increases the frequency, rate or extent of muscle adaptation.
14745	negative regulation of muscle adaptation	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of muscle adaptation.
14746	regulation of tonic skeletal muscle contraction	P	Any process that modulates the frequency, rate or extent of tonic skeletal muscle contraction.
14747	positive regulation of tonic skeletal muscle contraction	P	Any process that activates or increases the frequency, rate or extent of tonic skeletal muscle contraction.
14748	negative regulation of tonic skeletal muscle contraction	P	Any process that stops, prevents, or reduces the frequency, rate or extent of tonic skeletal muscle contraction.
14801	longitudinal sarcoplasmic reticulum	C	The portion of the free sarcoplasmic reticulum consisting of longitudinal tubules that connect terminal cisternae.
14802	terminal cisterna	C	The portion of sarcoplasmic reticulum devoted to calcium ion storage and calcium ion release.
14803	longitudinal sarcoplasmic reticulum lumen	C	The region between the inner and outer lipid bilayers of the longitudinal sarcoplasmic reticulum envelope. The longitudinal sarcoplasmic reticulum lumen is continuous with the lumen contained within the terminal cisternae.
14804	terminal cisterna lumen	C	The region between the inner and outer lipid bilayers of the terminal cisterna envelope. This space is enriched in calsequestrin.
14805	smooth muscle adaptation	P	Any process in which smooth muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. These adaptive events occur in both muscle fibers and associated structures (motoneurons and capillaries), and they involve alterations in regulatory mechanisms, contractile properties and metabolic capacities.
14806	smooth muscle hyperplasia	P	A process, occurring in smooth muscle, in which there is an increase in cell number by cell division, often leading to an increase in the size of an organ.
14807	regulation of somitogenesis	P	Any process that modulates the frequency, rate or extent of somitogenesis.
14808	release of sequestered calcium ion into cytosol by sarcoplasmic reticulum	P	The process in which the release of sequestered calcium ion by sarcoplasmic reticulum into cytosol occurs via calcium release channels.
14809	regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion	P	Any process that modulates the frequency, rate or extent of skeletal muscle contraction via the regulation of the release of sequestered calcium ion by sarcoplasmic reticulum into cytosol. The sarcoplasmic reticulum is the endoplasmic reticulum of striated muscle, specialised for the sequestration of calcium ions that are released upon receipt of a signal relayed by the T tubules from the neuromuscular junction.
14810	positive regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion	P	Any process that activates, maintains or increases the frequency, rate or extent of skeletal muscle contraction via the regulation of the release of sequestered calcium ion by sarcoplasmic reticulum into cytosol. The sarcoplasmic reticulum is the endoplasmic reticulum of striated muscle, specialised for the sequestration of calcium ions that are released upon receipt of a signal relayed by the T tubules from the neuromuscular junction.
14811	negative regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion	P	Any process that stops, prevents, or reduces the frequency, rate or extent of skeletal muscle contraction via the regulation of the release of sequestered calcium ion by sarcoplasmic reticulum into cytosol. The sarcoplasmic reticulum is the endoplasmic reticulum of striated muscle, specialised for the sequestration of calcium ions that are released upon receipt of a signal relayed by the T tubules from the neuromuscular junction.
14812	muscle cell migration	P	The orderly movement of a muscle cell from one site to another, often during the development of a multicellular organism.
14813	skeletal muscle satellite cell commitment	P	The process in which the developmental fate of a cell becomes restricted such that it will develop into a satellite cell.
14814	axon regeneration at neuromuscular junction	P	The regrowth of axons following their loss or damage at the neuromuscular junction. Motor axons regenerate after injury and they form neuro-muscular junctions with skeletal myofibers similar to normal ones.
14815	initiation of skeletal muscle satellite cell activation by growth factor signalling, involved in skeletal muscle regeneration	P	Signalling between growth factors and their receptors that results in the activation of satellite cell, where this process is involved in skeletal muscle regeneration. Satellite cells are quiescent cells that are located between the basal lamina and the plasmalemma of the muscle fiber, which are the main contributors to postnatal muscle growth. In adult muscle, satellite cells become activated to divide and differentiate in response to muscle damage.
14816	skeletal muscle satellite cell differentiation	P	The process in which a relatively unspecialized cell acquires specialized features of a satellite cell.
14817	skeletal muscle satellite cell fate specification	P	The process in which a cell becomes capable of differentiating autonomously into a skeletal muscle satellite cell in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed.
14818	skeletal muscle satellite cell fate determination	P	The process in which a cell becomes capable of differentiating autonomously into a skeletal muscle satellite cell regardless of its environment; upon determination, the cell fate cannot be reversed.
14819	regulation of skeletal muscle contraction	P	Any process that modulates the frequency, rate or extent of skeletal muscle contraction.
14820	tonic smooth muscle contraction	P	A process in which force is generated within tonic smooth muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. In the tonic smooth muscle, the muscle contraction occurs without an ordered sarcomeric structure. Tonic smooth muscle contraction occurs as a sustained continuous contraction.
14821	phasic smooth muscle contraction	P	A process in which force is generated within phasic smooth muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. In the phasic smooth muscle, the muscle contraction occurs without an ordered sarcomeric structure. Phasic smooth muscle contraction occurs in a series of discrete contractions and relaxations.
14822	detection of wounding	P	The series of events by which an injury stimulus is received and converted into a molecular signal.
14823	response to activity	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an activity stimulus.
14824	artery smooth muscle contraction	P	A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the artery. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The artery is a vessel carrying blood away from the heart.
14825	stomach fundus smooth muscle contraction	P	A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the fundus of stomach. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The fundus is the portion of the stomach that lies above the cardiac notch.
14826	vein smooth muscle contraction	P	A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the vein. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The vein is a vessel carrying blood away from the capillary beds.
14827	intestine smooth muscle contraction	P	A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the intestine. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The intestine is the section of the alimentary canal from the stomach to the anal canal. It includes the large intestine and small intestine.
14828	distal stomach smooth muscle contraction	P	A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the distal stomach. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The distal stomach is composed of the lower body and antrum and develops strong peristaltic phasic contractions that increase in amplitude as they propagate toward the pylorus.
14829	vascular smooth muscle contraction	P	A process, occurring in the vascular tissue, whereby actin/myosin complex activity generates force through ATP hydrolysis resulting in a change in smooth muscle geometry. This process is always coupled to chemo-mechanical energy conversion.
14830	arteriole smooth muscle contraction	P	A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the arteriole. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The arteriole is the smallest division of the artery located between the muscular arteries and the capillaries.
14831	gastro-intestinal system smooth muscle contraction	P	A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the gastro-intestinal system. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The gastro-intestinal system generally refers to the digestive structures stretching from the mouth to anus, but does not include the accessory glandular organs (liver, pancreas and biliary tract).
14832	urinary bladder smooth muscle contraction	P	A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the urinary bladder. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The urinary bladder is a musculomembranous sac along the urinary tract.
14833	skeletal muscle satellite stem cell asymmetric division	P	The asymmetric division of a skeletal muscle satellite stem cell to produce two daughter cells, one of which is destined to differentiate and the other to be a quiescent cell that restocks the satellite cell pool.
14834	skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration	P	Any process by which the number of skeletal muscle satellite cells in a skeletal muscle is maintained during muscle regeneration. There are at least three mechanisms by which this is achieved. Skeletal muscle satellite stem cell asymmetric division ensures satellite stem cell numbers are kept constant. Symmetric division of these cells amplifies the number of skeletal muscle satellite stem cells. Some adult skeletal muscle myoblasts (descendants of activated satellite cells) can develop back into quiescent satellite cells, replenishing the overall pool of satellite cells.
14835	myoblast differentiation involved in skeletal muscle regeneration	P	The process in which a relatively unspecialized satellite cell acquires specialized features of a myoblast. This occurs as part of skeletal muscle regeneration. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.
14836	myoblast fate commitment involved in skeletal muscle regeneration	P	The process in which the developmental fate of a satellite cell becomes restricted such that it will develop into a myoblast. This occurs as part of skeletal muscle regeneration. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.
14837	myoblast fate determination involved in skeletal muscle regeneration	P	The process in which a satellite cell becomes capable of differentiating autonomously into a myoblast regardless of its environment; upon determination, the cell fate cannot be reversed. This occurs as part of skeletal muscle regeneration. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.
14838	myoblast fate specification involved in skeletal muscle regeneration	P	The process in which a satellite cell becomes capable of differentiating autonomously into a myoblast in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed. This occurs as part of skeletal muscle regeneration. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.
14839	myoblast migration involved in skeletal muscle regeneration	P	The process in which a myoblast migrates along an entire fiber to the site of injury. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.
14841	skeletal muscle satellite cell proliferation	P	The multiplication or reproduction of satellite cells, resulting in the expansion of the cell population. Satellite cells are quiescent cells that are located between the basal lamina and the plasmalemma of the muscle fiber, which are the main contributors to postnatal muscle growth. In adult muscle, satellite cells become activated to divide and differentiate in response to muscle damage.
14842	regulation of skeletal muscle satellite cell proliferation	P	Any process that modulates the frequency, rate or extent of skeletal muscle satellite cell proliferation.
14843	growth factor dependent regulation of skeletal muscle satellite cell proliferation	P	Any process that modulates the frequency, rate or extent of satellite cell proliferation; dependent on specific growth factor activity such as fibroblast growth factors and transforming growth factor beta.
14844	myoblast proliferation involved in skeletal muscle regeneration	P	The multiplication or reproduction of myoblasts, resulting in the expansion of the cell population. This occurs as part of skeletal muscle regeneration. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.
14845	stomach body smooth muscle contraction	P	A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the body of stomach. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The body of stomach is the part of the stomach that lies between the fundus above and the pyloric antrum below; its boundaries are poorly defined.
14846	esophagus smooth muscle contraction	P	A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the esophagus. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The esophagus is the muscular membranous segment between the pharynx and the stomach in the upper gastrointestinal tract.
14847	proximal stomach smooth muscle contraction	P	A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the proximal stomach. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The proximal stomach, composed of the fundus and upper body, shows low frequency, sustained tonic contractions that are responsible for generating a basal pressure within the stomach.
14848	urinary tract smooth muscle contraction	P	A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the urinary tract. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The urinary tract consists of organs of the body that produce and discharge urine. These include the kidneys, ureters, bladder, and urethra.
14849	ureter smooth muscle contraction	P	A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the ureter. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The ureter is one of a pair of thick-walled tubes that transports urine from the kidney pelvis to the urinary bladder.
14850	response to muscle activity	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a muscle activity stimulus.
14852	regulation of skeletal muscle contraction by neural stimulation via neuromuscular junction	P	Any process that modulates the frequency, rate or extent of skeletal muscle contraction by variation of the pattern of stimulation by nervous system.
14853	regulation of excitatory postsynaptic membrane potential involved in skeletal muscle contraction	P	Any process, involved in skeletal muscle contraction, that modulates the establishment or extent of the excitatory postsynaptic potential (EPSP). Excitatory postsynaptic potential (EPSP) is a temporay increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell. The flow of ions that causes an EPSP is an excitatory postsynaptic current (EPSC) and makes it easier for the neuron to fire an action potential.
14854	response to inactivity	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an inactivity stimulus.
14855	striated muscle cell proliferation	P	The multiplication or reproduction of striated muscle cells, resulting in the expansion of a cell population. Striated muscles contain fibers that are divided by transverse bands into striations, and cardiac and skeletal muscle are types of striated muscle.
14856	skeletal muscle cell proliferation	P	The multiplication or reproduction of skeletal muscle cells, resulting in the expansion of a cell population.
14857	regulation of skeletal muscle cell proliferation	P	Any process that modulates the frequency, rate or extent of skeletal muscle cell proliferation.
14858	positive regulation of skeletal muscle cell proliferation	P	Any process that activates or increases the frequency, rate or extent of skeletal muscle cell proliferation.
14859	negative regulation of skeletal muscle cell proliferation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of skeletal muscle cell proliferation.
14860	neurotransmitter secretion involved in regulation of skeletal muscle contraction	P	The regulated release of neurotransmitter into the synaptic cleft involved in skeletal muscle contraction. A neurotransmitter is any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell. Among the many substances that have the properties of a neurotransmitter are acetylcholine, noradrenaline, adrenaline, dopamine, glycine, gamma aminobutyrate, glutamic acid, substance P, enkephalins, endorphins and serotonin.
14861	regulation of skeletal muscle contraction via regulation of action potential	P	Any process that modulates the frequency, rate or extent of skeletal muscle contraction by depolarization of muscle membrane and ionic fluxes.
14862	regulation of skeletal muscle contraction by chemo-mechanical energy conversion	P	Any process that modulates the frequency, rate or extent of skeletal muscle contraction by regulating force and velocity of shortening. The force of skeletal muscle contraction is produced by acto-myosin interaction processes through formation of cross bridges. The shortening leads to reduction of length of muscle fiber and sarcomeres.
14863	detection of inactivity	P	The series of events in which a inactivity stimulus is received by a cell or organism and converted into a molecular signal.
14864	detection of muscle activity	P	The series of events in which a muscle activity stimulus is received by a cell and converted into a molecular signal.
14865	detection of activity	P	The series of events in which an activity stimulus is received by a cell and converted into a molecular signal.
14866	skeletal myofibril assembly	P	The process whose specific outcome is the progression of the skeletal myofibril over time, from its formation to the mature structure. A skeletal myofibril is a myofibril specific to skeletal muscle cells.
14868	cross bridge cycling involved in regulation of the velocity of shortening in skeletal muscle contraction	P	A process in which cross bridges are broken and reformed during filament sliding as part of the regulation of the velocity of shortening in skeletal muscle contraction.
14869	detection of muscle inactivity	P	The series of events in which a muscle inactivity stimulus is received by a cell and converted into a molecular signal.
14870	response to muscle inactivity	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a muscle inactivity stimulus.
14871	cross bridge formation involved in regulation of the velocity of shortening in skeletal muscle contraction	P	The process in which actin and myosin interact, split ATP and generate force during skeletal muscle contraction. This process is one of the components of the regulation of the force of skeletal muscle contraction.
14872	myoblast division	P	The process resulting in the physical partitioning and separation of a myoblast into daughter cells. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.
14873	response to muscle activity involved in regulation of muscle adaptation	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a muscle activity stimulus. This process occurs as part of the regulation of muscle adaptation.
14874	response to stimulus involved in regulation of muscle adaptation	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. This occurs as part of the regulation of muscle adaptation.
14875	detection of muscle activity involved in regulation of muscle adaptation	P	The series of events by which a muscle activity stimulus is received and converted into a molecular signal. This occurs as part of the regulation of muscle adaptation.
14876	response to injury involved in regulation of muscle adaptation	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a injury. This process occurs as part of the regulation of muscle adaptation.
14877	response to muscle inactivity involved in regulation of muscle adaptation	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a muscle inactivity stimulus. This process occurs as part of the regulation of muscle adaptation.
14878	response to electrical stimulus involved in regulation of muscle adaptation	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electrical stimulus. This process occurs as part of the regulation of muscle adaptation.
14879	detection of electrical stimulus involved in regulation of muscle adaptation	P	The series of events by which an electrical stimulus is received and converted into a molecular signal. This occurs as part of the regulation of muscle adaptation.
14880	regulation of muscle filament sliding involved in regulation of the velocity of shortening in skeletal muscle contraction	P	Any process that modulates the frequency, rate or extent of muscle filament sliding, and consequently contributes to the regulation of the velocity of shortening of skeletal muscle contraction.
14881	regulation of myofibril size	P	Any process that modulates the size of myofibrils. A myofibril is the contractile element of skeletal and cardiac muscle. It is a long, highly organized bundle of actin, myosin, and other proteins that contracts by a sliding filament mechanism.
14882	regulation of myofibril number	P	Any process that modulates the number of myofibrils. A myofibril is the contractile element of skeletal and cardiac muscle. It is a long, highly organized bundle of actin, myosin, and other proteins that contracts by a sliding filament mechanism.
14883	transition between fast and slow fiber	P	The process of conversion of fast-contracting muscle fibers to a slower character. This may involve slowing of contractile rate, slow myosin gene induction, increase in oxidative metabolic properties, altered electrophysiology and altered innervation. This process also regulates skeletal muscle adapatation.
14884	detection of muscle inactivity involved in regulation of muscle adaptation	P	The series of events in which a muscle inactivity stimulus is received by a cell and converted into a molecular signal. This occurs as part of the regulation of muscle adaptation.
14885	detection of injury involved in regulation of muscle adaptation	P	The series of events by which an injury stimulus is received and converted into a molecular signal. This occurs as part of the regulation of muscle adaptation.
14886	transition between slow and fast fiber	P	The process of conversion of slow-contracting muscle fibers to a faster character. This may involve increasing of contractile rate, fast myosin gene induction, increase in glycolytic metabolic properties, altered electrophysiology and altered innervation. This process also regulates skeletal muscle adapatation.
14887	cardiac muscle adaptation	P	The process in which cardiac muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors.
14888	striated muscle adaptation	P	Any process in which striated muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. These adaptive events occur in both muscle fibers and associated structures (motoneurons and capillaries), and they involve alterations in regulatory mechanisms, contractile properties and metabolic capacities.
14889	muscle atrophy	P	A process, occurring in the muscle, that is characterized by a decrease in protein content, fiber diameter, force production and fatigue resistance in response to different conditions such as starvation, aging and disuse.
14890	smooth muscle atrophy	P	A process, occurring in smooth muscle, that is characterized by a decrease in protein content, fiber diameter, force production and fatigue resistance in response to different conditions such as starvation, aging and disuse.
14891	striated muscle atrophy	P	A process, occurring in striated muscle, that is characterized by a decrease in protein content, fiber diameter, force production and fatigue resistance in response to different conditions such as starvation, aging and disuse.
14893	response to rest involved in regulation of muscle adaptation	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a rest stimulus. This process occurs as part of the regulation of muscle adaptation.
14894	response to denervation involved in regulation of muscle adaptation	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a denervation stimulus. This process occurs as part of the regulation of muscle adaptation.
14895	smooth muscle hypertrophy	P	The enlargement or overgrowth of all or part of an organ due to an increase in size of its smooth muscle cells without cell division. Physiological hypertrophy is a normal process during development, and can also occur in mature structures on demand. In the uterus, smooth muscle cells undergo hypertrophy during pregnancy.
14896	muscle hypertrophy	P	The muscle system process that results in enlargement or overgrowth of all or part of a muscle organ due to an increase in the size of its muscle cells. Physiological hypertrophy is a normal process during development (it stops in cardiac muscle after adolescence) and can also be brought on in response to demand. In athletes cardiac and skeletal muscles undergo hypertrophy stimulated by increasing muscle activity on exercise. Smooth muscle cells in the uterus undergo hypertrophy during pregnancy.
14897	striated muscle hypertrophy	P	The enlargement or overgrowth of all or part of an organ due to an increase in size of muscle cells without cell division. In the case of striated muscle, this happens due to the additional synthesis of sarcomeric proteins and assembly of myofibrils.
14898	cardiac muscle hypertrophy in response to stress	P	The physiological enlargement or overgrowth of all or part of the heart muscle due to an increase in size (not length) of individual cardiac muscle fibers, without cell division, as a result of a disturbance in organismal or cellular homeostasis.
14899	cardiac muscle atrophy	P	A process, occurring in the heart, in which a decrease in cell mass and then in heart size occurs due to shrinking of the individual cells. The shrinkage is caused by protein degradation.
14900	muscle hyperplasia	P	A muscle system process that results in an increase in cell number by cell division, often leading to an increase in the size of an organ.
14901	satellite cell activation involved in skeletal muscle regeneration	P	The process that initiates skeletal muscle satellite cell division by causing it to move from quiescence to the G1 stage of the cell cycle. The cell swells and there are a number of other small changes. The cells then start to divide. Following cell division the cells will differentiate. In adult muscle, satellite cells become activated to divide and differentiate in response to muscle damage.
14902	myotube differentiation	P	The process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotube differentiation starts with myoblast fusion and the appearance of specific cell markers (this is the cell development step). Then individual myotubes can fuse to form bigger myotubes and start to contract. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse.
14904	myotube cell development	P	The process aimed at the progression of a myotube cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse.
14905	myoblast fusion involved in skeletal muscle regeneration	P	A process in which non-proliferating myoblasts, after migrating to the site of injury, fuse into existing damaged fibers or fuse to myotubes to form new fibers, as part of the process of skeletal muscle regeneration. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.
14906	myotube cell development involved in skeletal muscle regeneration	P	The process aimed at the progression of a myotube cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. This occurs as part of the process of skeletal muscle regeneration. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse.
14908	myotube differentiation involved in skeletal muscle regeneration	P	The process in which a relatively unspecialized cell acquires specialized features of a myotube cell. Myotube differentiation starts with myoblast fusion and the appearance of specific cell markers (this is the cell development step). Then individual myotubes can fuse to form bigger myotubes and start to contract. This process occurs as part of the process of skeletal muscle regeneration. Myotubes are multinucleated cells that are formed when proliferating myoblasts exit the cell cycle, differentiate and fuse.
14909	smooth muscle cell migration	P	The orderly movement of a smooth muscle cell from one site to another, often during the development of a multicellular organism.
14910	regulation of smooth muscle cell migration	P	Any process that modulates the frequency, rate or extent of smooth muscle cell migration.
14911	positive regulation of smooth muscle cell migration	P	Any process that activates, maintains or increases the frequency, rate or extent of smooth muscle cell migration.
14912	negative regulation of smooth muscle cell migration	P	Any process that stops, prevents, or reduces the frequency, rate or extent of smooth muscle cell migration.
14914	myoblast maturation involved in muscle regeneration	P	A developmental process, independent of morphogenetic (shape) change, that is required for a myoblast cell to attain its fully functional state involved in muscle regeneration. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.
14915	regulation of muscle filament sliding speed involved in regulation of the velocity of shortening in skeletal muscle contraction	P	Any process that modulates the velocity of muscle filament sliding, and consequently contributes to the regulation of the velocity of shortening of skeletal muscle contraction.
14916	regulation of lung blood pressure	P	The process that modulates the force with which blood travels through the lungs. The process is controlled by a balance of processes that increase pressure and decrease pressure.
15002	heme-copper terminal oxidase activity	F	Catalysis of the four-electron reduction of dioxygen (O2) to water, coupled to generation of a proton electrochemical gradient across a membrane.
15009	corrin metabolic process	P	The chemical reactions and pathways involving corrin, C19H22N4, the fundamental heterocyclic skeleton of the corrinoids. It consists of four reduced pyrrole rings joined into a macrocyclic ring. Corrin is the core of the vitamin B12 molecule.
15010	tetrahydrocorphin metabolic process	P	The chemical reactions and pathways involving tetrahydrocorphins, tetrapyrroles that combine the structural elements of both porphyrins and corrins.
15011	nickel-tetrapyrrole coenzyme metabolic process	P	The chemical reactions and pathways involving an enzyme cofactor consisting of a tetrapyrrole structure containing nickel, such as the F-430 cofactor found in methyl-coenzyme M reductase.
15012	heparan sulfate proteoglycan biosynthetic process	P	The chemical reactions and pathways resulting in the formation of the heparan sulfate proteoglycan, a glycosaminoglycan with repeat unit consisting of alternating alpha-(1->4)-linked hexuronic acid and glucosamine residues; the former are a mixture of sulfated and nonsulfated D-glucuronic acid and L-iduronic acid; the L-iduronic acid is either sulfated or acetylated on its amino group as well as being sulfated on one of its hydroxyl groups; heparan sulfate chains are covalently linked to peptidyl-serine by a glycosidic attachment through the trisaccharide galactosyl-galactosyl-xylosyl to serine residues.
15013	heparan sulfate proteoglycan biosynthetic process, linkage to polypeptide	P	The polymerization of one or more heparan sulfate chains via a xylose link onto serine residues in the core protein of a proteoglycan.
15014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process	P	The chemical reactions and pathways resulting in the formation of polysaccharide chain component of heparan sulfate proteoglycan.
15015	heparan sulfate proteoglycan biosynthetic process, enzymatic modification	P	The modification, often by sulfation, of sugars incorporated into heparan sulfate after polymerization.
15016	[heparan sulfate]-glucosamine N-sulfotransferase activity	F	Catalysis of the reaction: 3'-phosphoadenylyl sulfate + [heparan sulfate]-glucosamine = adenosine 3',5'-bisphosphate + [heparan sulfate]-N-sulfoglucosamine.
15018	galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity	F	Catalysis of the reaction: UDP-glucuronate + 3-beta-D-galactosyl-4-beta-D-galactosyl-O-beta-D-xylosylprotein = UDP + 3-beta-D-glucuronosyl-3-beta-D-galactosyl-4-beta-D-galactosyl-O-beta-D-xylosylprotein.
15019	heparan-alpha-glucosaminide N-acetyltransferase activity	F	Catalysis of the reaction: acetyl-CoA + heparan alpha-D-glucosaminide = CoA + heparan N-acetyl-alpha-D-glucosaminide.
15020	glucuronosyltransferase activity	F	Catalysis of the reaction: UDP-glucuronate + acceptor = UDP + acceptor beta-D-glucuronoside.
15021	heparin-sulfate lyase activity	F	Catalysis of the elimination of sulfate; appears to act on linkages between N-acetyl-D-glucosamine and uronate. Product is an unsaturated sugar.
15024	glucuronate-2-sulfatase activity	F	Catalysis of the hydrolysis of the 2-sulfate groups of the 2-O-sulfo-D-glucuronate residues of chondroitin sulfate, heparin and heparitin sulfate.
15026	coreceptor activity	F	Combining with an extracellular or intracellular messenger, and in cooperation with a nearby primary receptor, initiating a change in cell activity.
15030	Cajal body	C	A class of nuclear body, first seen after silver staining by Ramon y Cajal in 1903, enriched in small nuclear ribonucleoproteins, and certain general RNA polymerase II transcription factors; ultrastructurally, they appear as a tangle of coiled, electron-dense threads roughly 0.5 micrometers in diameter; involved in aspects of snRNP biogenesis; the protein coilin serves as a marker for Cajal bodies. Some argue that Cajal bodies are the sites for preassembly of transcriptosomes, unitary particles involved in transcription and processing of RNA.
15031	protein transport	P	The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
15032	storage protein import into fat body	P	The incorporation of hemolymph proteins by cells of the fat body of holometabolous insects, during the final larval stage. Uptake of these proteins prepares the insect for pupation and metamorphosis, since insect pupae do not feed and therefore depend on material that has been accumulated during larval life.
15035	protein disulfide oxidoreductase activity	F	Catalysis of the reaction: a protein with reduced sulfide groups = a protein with oxidized disulfide bonds.
15036	disulfide oxidoreductase activity	F	Catalysis of the reaction: substrate with reduced sulfide groups = substrate with oxidized disulfide bonds.
15037	peptide disulfide oxidoreductase activity	F	Catalysis of the reaction: a peptide with reduced sulfide groups = a peptide with oxidized disulfide bonds.
15038	glutathione disulfide oxidoreductase activity	F	Catalysis of the reaction: 2 glutathione + electron acceptor = glutathione disulfide + electron donor.
15039	NADPH-adrenodoxin reductase activity	F	Catalysis of the reaction: oxidized adrenodoxin + NADPH + H+ = reduced adrenodoxin + NADP+.
15042	trypanothione-disulfide reductase activity	F	Catalysis of the reaction: NADP+ + trypanothione = NADPH + H+ + trypanothione disulfide.
15043	leghemoglobin reductase activity	F	Catalysis of the reaction: NADPH + H+ + 2 ferrileghemoglobin = NADP+ + 2 ferroleghemoglobin.
15044	rubredoxin-NAD+ reductase activity	F	Catalysis of the reaction: reduced rubredoxin + NAD+ = oxidized rubredoxin + NADH + H+.
15045	rubredoxin-NAD(P)+ reductase activity	F	Catalysis of the reaction: reduced rubredoxin + NAD(P)+ = oxidized rubredoxin + NAD(P)H + H+.
15046	rubredoxin-NADP reductase activity	F	Catalysis of the reaction: reduced rubredoxin + NADP+ = oxidized rubredoxin + NADPH + H+.
15047	NADPH-cytochrome-c2 reductase activity	F	Catalysis of the reaction: NADPH + H+ + 2 ferricytochrome c2 = NADP+ + 2 ferrocytochrome c2.
15048	phthalate dioxygenase reductase activity	F	Catalysis of the transfer of electrons between pyridine nucleotides (obligatory two-electron carriers) and hemes or (2Fe-2S) centers (obligatory one-electron carriers) in respiration, photosynthesis, and many oxygenase systems.
15049	methane monooxygenase activity	F	Catalysis of the reaction: methane + NAD(P)H + H+ + O2 = methanol + NAD(P)+ + H2O.
15050	methane monooxygenase complex	C	A protein complex that possesses methane monooxygenase activity; dimeric and trimeric complexes have been characterized.
15052	beta3-adrenergic receptor activity	F	Combining with epinephrine or norepinephrine to initiate a change in cell activity via activation of a G protein, with pharmacological characteristics of beta3-adrenergic receptors.
15054	gastrin receptor activity	F	Combining with gastrin and transmitting the signal across the membrane by activating an associated G-protein to initiate a change in cell activity.
15055	secretin receptor activity	F	Combining with secretin to initiate a change in cell activity.
15056	corticotrophin-releasing factor receptor activity	F	Combining with the corticotrophin-releasing factor family of ligands, including the urocortins, to initiate a change in cell activity.
15057	thrombin-activated receptor activity	F	A G-protein-coupled receptor activity that is activated by cleavage by thrombin, which exposes a tethered ligand corresponding to the new N-terminus, which binds to the receptor and activates it.
15065	uridine nucleotide receptor activity	F	Combining with UTP or UDP to initiate a change in cell activity.
15066	alpha-amylase inhibitor activity	F	Stops, prevents or reduces the activity of alpha-amylase.
15067	amidinotransferase activity	F	Catalysis of the reversible transfer of an amidino group to an acceptor.
15068	glycine amidinotransferase activity	F	Catalysis of the reaction: L-arginine + glycine = L-ornithine + guanidinoacetate.
15069	scyllo-inosamine-4-phosphate amidinotransferase activity	F	Catalysis of the reaction: 1-amino-1-deoxy-scyllo-inositol 4-phosphate + L-arginine = 1-guanidino-1-deoxy-scyllo-inositol 4-phosphate + L-ornithine.
15074	DNA integration	P	The process in which a segment of DNA is incorporated into another, usually larger, DNA molecule such as a chromosome.
15075	ion transmembrane transporter activity	F	Enables the transfer of an ion from one side of a membrane to the other.
15077	monovalent inorganic cation transmembrane transporter activity	F	Enables the transfer of a inorganic cations with a valency of one from one side of a membrane to the other. Inorganic cations are atoms or small molecules with a positive charge that do not contain carbon in covalent linkage.
15078	hydrogen ion transmembrane transporter activity	F	Enables the transfer of hydrogen ions from one side of a membrane to the other.
15079	potassium ion transmembrane transporter activity	F	Enables the transfer of potassium ions (K+) from one side of a membrane to the other.
15080	silver ion transmembrane transporter activity	F	Enables the transfer of silver (Ag) ions from one side of a membrane to the other.
15081	sodium ion transmembrane transporter activity	F	Enables the transfer of sodium ions (Na+) from one side of a membrane to the other.
15083	aluminum ion transmembrane transporter activity	F	Enables the transfer of aluminum (Al) ions from one side of a membrane to the other.
15085	calcium ion transmembrane transporter activity	F	Enables the transfer of calcium (Ca) ions from one side of a membrane to the other.
15086	cadmium ion transmembrane transporter activity	F	Enables the transfer of cadmium (Cd) ions from one side of a membrane to the other.
15087	cobalt ion transmembrane transporter activity	F	Enables the transfer of cobalt (Co) ions from one side of a membrane to the other.
15088	copper uptake transmembrane transporter activity	F	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Cu+(out) = Cu+(in).
15089	high-affinity copper ion transmembrane transporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Cu2+(out) = Cu2+(in). In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.
15090	low-affinity iron ion transmembrane transporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Fe2+(out) = Fe2+(in). In low-affinity transport the transporter is able to bind the solute only if it is present at very high concentrations.
15091	ferric iron transmembrane transporter activity	F	Enables the transfer of ferric iron (Fe(III) or Fe3+) ions from one side of a membrane to the other.
15092	high-affinity ferric uptake transmembrane transporter activity	F	Enables the transfer of Fe(III) from the outside of a cell to the inside of a cell across a membrane. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.
15093	ferrous iron transmembrane transporter activity	F	Enables the transfer of ferrous iron (Fe(II) or Fe2+) ions from one side of a membrane to the other.
15094	lead ion transmembrane transporter activity	F	Enables the transfer of lead (Pb) ions from one side of a membrane to the other.
15095	magnesium ion transmembrane transporter activity	F	Enables the transfer of magnesium (Mg) ions from one side of a membrane to the other.
15097	mercury ion transmembrane transporter activity	F	Enables the transfer of mercury (Hg) ions from one side of a membrane to the other.
15098	molybdate ion transmembrane transporter activity	F	Enables the transfer of molybdate (MoO4 2-) ions from one side of a membrane to the other. Molybdate is the bivalent anion derived from molybdic acid.
15099	nickel cation transmembrane transporter activity	F	Enables the transfer of nickel (Ni) cations from one side of a membrane to the other.
15100	vanadium ion transmembrane transporter activity	F	Enables the transfer of vanadium (V) ions from one side of a membrane to the other.
15101	organic cation transmembrane transporter activity	F	Enables the transfer of organic cations from one side of a membrane to the other. Organic cations are atoms or small molecules with a positive charge that contain carbon in covalent linkage.
15103	inorganic anion transmembrane transporter activity	F	Enables the transfer of inorganic anions from one side of a membrane to the other. Inorganic anions are atoms or small molecules with a negative charge which do not contain carbon in covalent linkage.
15104	antimonite transmembrane transporter activity	F	Enables the transfer of antimonite from one side of a membrane to the other.
15105	arsenite transmembrane transporter activity	F	Enables the transfer of arsenite from one side of a membrane to the other.
15106	bicarbonate transmembrane transporter activity	F	Enables the transfer of bicarbonate from one side of a membrane to the other. Bicarbonate is the hydrogencarbonate ion, HCO3-.
15107	chlorate transmembrane transporter activity	F	Enables the transfer of chlorate, ClO3-, from one side of a membrane to the other.
15108	chloride transmembrane transporter activity	F	Enables the transfer of chloride ions from one side of a membrane to the other.
15109	chromate transmembrane transporter activity	F	Enables the transfer of chromate from one side of a membrane to the other. Chromate is the anion of chromic acid, H2CrO4 (aq) or CrO3.
15110	cyanate transmembrane transporter activity	F	Enables the transfer of cyanate, NCO-, the anion of cyanic acid, from one side of a membrane to the other.
15111	iodide transmembrane transporter activity	F	Enables the transfer of iodide ions from one side of a membrane to the other.
15112	nitrate transmembrane transporter activity	F	Enables the transfer of nitrate ions (NO3-) from one side of a membrane to the other.
15113	nitrite transmembrane transporter activity	F	Enables the transfer of nitrite (NO2-) ions from one side of a membrane to the other.
15114	phosphate ion transmembrane transporter activity	F	Enables the transfer of phosphate (PO4 3-) ions from one side of a membrane to the other.
15115	silicate transmembrane transporter activity	F	Enables the transfer of silicates from one side of a membrane to the other. Silicates are the salts of silicic acids, and are usually composed of silicon and oxygen (Si[x]O[y]), one or more metals, and possibly hydrogen. Types of silicate include unisilicates, metasilicates and hydrous silicates.
15116	sulfate transmembrane transporter activity	F	Enables the transfer of sulfate ions, SO4(2-), from one side of a membrane to the other.
15117	thiosulfate transmembrane transporter activity	F	Enables the transfer of thiosulfate ions, S2O3(2-), from one side of a membrane to the other.
15118	tellurite transmembrane transporter activity	F	Enables the transfer of tellurite from one side of a membrane to the other. Tellurite is a salt of tellurous acid or an oxide of tellurium which occurs sparingly in tufts of white or yellowish crystals.
15119	hexose phosphate transmembrane transporter activity	F	Enables the transfer of hexose phosphate from one side of the membrane to the other. Hexose phosphates is any of a group of monophosphorylated aldoses with a chain of six carbon atoms in the molecule.
15120	phosphoglycerate transmembrane transporter activity	F	Enables the transfer of phosphoglycerates from one side of the membrane to the other. Phosphoglycerates are important intermediates in glycolysis and 3-phosphoglycerate is a precursor in serine biosynthesis.
15121	phosphoenolpyruvate:phosphate antiporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: phosphoenolpyruvate(out) + phosphate(in) = phosphoenolpyruvate(in) + phosphate(out).
15123	acetate transmembrane transporter activity	F	Enables the transfer of acetate from one side of the membrane to the other. Acetate is the 2-carbon carboxylic acid ethanoic acid.
15124	allantoate transmembrane transporter activity	F	Enables the transfer of allantoate from one side of the membrane to the other. Allantoate is the end product of purine metabolism in mammals and some fish, formed form allantoin. It is widely distributed in plants as an important source of stored nitrogen.
15125	bile acid transmembrane transporter activity	F	Enables the transfer of bile acid from one side of the membrane to the other. Bile acids are any of a group of steroid carboxylic acids occurring in bile, where they are present as the sodium salts of their amides with glycine or taurine.
15126	canalicular bile acid transmembrane transporter activity	F	The directed movement of bile acid and bile salts out of a hepatocyte and into the bile canaliculus by means of an agent such as a transporter or pore. Bile canaliculi are the thin tubes formed by hepatocyte membranes. Bile acids are any of a group of steroid carboxylic acids occurring in bile, where they are present as the sodium salts of their amides with glycine or taurine.
15127	bilirubin transmembrane transporter activity	F	Enables the transfer of bilirubin from one side of the membrane to the other. Bilirubin is a linear tetrapyrrole produced in the reticuloendothelial system from biliverdin and transported to the liver as a complex with serum albumin. In the liver, bilirubin is converted to bilirubin bisglucuronide, which is excreted in the bile.
15128	gluconate transmembrane transporter activity	F	Enables the transfer of gluconate from one side of the membrane to the other. Gluconate is the aldonic acid derived from glucose.
15129	lactate transmembrane transporter activity	F	Catalysis of the transfer of lactate from one side of the membrane to the other. Lactate is 2-hydroxypropanoate, CH3-CHOH-COOH; L(+)-lactate is formed by anaerobic glycolysis in animal tissues, and DL-lactate is found in sour milk, molasses and certain fruit juices.
15130	mevalonate transmembrane transporter activity	F	Enables the transfer of mevalonate from one side of the membrane to the other. Mevalonate is the anion of mevalonic acid; its (R)-enantiomer is a strategic intermediate derived from hydroxymethylglutaryl-CoA in the biosynthesis of polyprenyl compounds.
15131	oxaloacetate transmembrane transporter activity	F	Enables the transfer of oxaloacetate, the anion of oxobutanedioic acid, from one side of the membrane to the other.
15132	prostaglandin transmembrane transporter activity	F	Enables the transfer of prostaglandins from one side of the membrane to the other. A prostaglandin is any of a group of biologically active metabolites which contain a cyclopentane ring due to the formation of a bond between two carbons of a fatty acid. They have a wide range of biological activities.
15133	uronic acid transmembrane transporter activity	F	Enables the transfer of uronic acid from one side of the membrane to the other. Uronic acids are any monocarboxylic acid formally derived by oxidizing to a carboxyl group the terminal hydroxymethylene group of either an aldose with four or more carbon atoms in the molecule, or of any glycoside derived from such an aldose.
15134	hexuronate transmembrane transporter activity	F	Enables the transfer of hexuronates from one side of the membrane to the other. A hexuronate is any monocarboxylic acid derived from a hexose by oxidation of C-6.
15135	glucuronate transmembrane transporter activity	F	Enables the transfer of glucuronate from one side of the membrane to the other. Glucuronate is the uronic acid formally derived from glucose by oxidation of the hydroxymethylene group at C-6 to a carboxyl group.
15136	sialic acid transmembrane transporter activity	F	Enables the transfer of sialic acid from one side of the membrane to the other.
15137	citrate transmembrane transporter activity	F	Enables the transfer of citrate, 2-hydroxy-1,2,3-propanetricarboyxlate, from one side of the membrane to the other.
15138	fumarate transmembrane transporter activity	F	Enables the transfer of fumarate from one side of the membrane to the other. Fumarate is a key intermediate in metabolism and is formed in the TCA cycle from succinate and converted into malate.
15139	alpha-ketoglutarate transmembrane transporter activity	F	Enables the transfer of alpha-ketoglutarate from one side of the membrane to the other. Alpha-ketoglutarate (or oxoglutarate) is a compound with important roles in carbohydrate and amino acid metabolism, especially in transamination reactions and as a component of the TCA cycle.
15140	malate transmembrane transporter activity	F	Enables the transfer of malate from one side of the membrane to the other. Malate is a chiral hydroxydicarboxylic acid, hydroxybutanedioic acid. The (+) enantiomer is an important intermediate in metabolism as a component of both the TCA cycle and the glyoxylate cycle.
15141	succinate transmembrane transporter activity	F	Enables the transfer of succinate, the dianion of ethane dicarboxylic acid, from one side of the membrane to the other.
15142	tricarboxylic acid transmembrane transporter activity	F	Enables the transfer of tricarboxylic acids from one side of the membrane to the other. Tricarboxylic acid are organic acids with three COOH groups.
15143	urate transmembrane transporter activity	F	Enables the transfer of urate from one side of the membrane to the other. Urate is the anion of uric acid, 2,6,8-trioxypurine, the end product of purine metabolism in certain mammals and the main excretory product in uricotelic animals.
15144	carbohydrate transmembrane transporter activity	F	Enables the transfer of carbohydrate from one side of the membrane to the other.
15145	monosaccharide transmembrane transporter activity	F	Enables the transfer of a monosaccharide from one side of a membrane to the other.
15146	pentose transmembrane transporter activity	F	Enables the transfer of a pentose sugar, a monosaccharide with 5 carbon atoms, from one side of the membrane to the other.
15147	L-arabinose transmembrane transporter activity	F	Enables the transfer of L-arabinose from one side of the membrane to the other. Arabinose occurs free, for example in the heartwood of many conifers and in the combined states, in both furanose and pyranose forms, as a constituent of various plant hemicelluloses, bacterial polysaccharides, etc.
15148	D-xylose transmembrane transporter activity	F	Enables the transfer of D-xylose from one side of the membrane to the other. D-xylose (the naturally occurring enantiomer is always D-) is a constituent of plant polysaccharides.
15149	hexose transmembrane transporter activity	F	Enables the transfer of a hexose sugar, a monosaccharide with 6 carbon atoms, from one side of a membrane to the other.
15150	fucose transmembrane transporter activity	F	Enables the transfer of fucose from one side of the membrane to the other. Fucose is 6-deoxygalactose and has two enantiomers, D-fucose and L-fucose.
15151	alpha-glucoside transmembrane transporter activity	F	Enables the transfer of alpha-glucosides from one side of the membrane to the other. Alpha-glucosides are glycosides in which the sugar group is a glucose residue, and the anomeric carbon of the bond is in an alpha configuration.
15152	glucose-6-phosphate transmembrane transporter activity	F	Catalysis of the transfer of glucose-6-phosphate from one side of the membrane to the other. Glucose-6-phosphate is a monophosphorylated derivative of glucose with the phosphate group attached to C-6.
15153	rhamnose transmembrane transporter activity	F	Enables the transfer of rhamnose from one side of the membrane to the other. Rhamnose occurs commonly as a compound of plant glycosides, in polysaccharides of gums and mucilages, and in bacterial polysaccharides. It is also a component of some plant cell wall polysaccharides and frequently acts as the sugar components of flavonoids.
15154	disaccharide transmembrane transporter activity	F	Enables the transfer of disaccharide from one side of the membrane to the other.
15155	lactose transmembrane transporter activity	F	Enables the transfer of lactose from one side of the membrane to the other. Lactose is a disaccharide 4-O-beta-D-galactopyranosyl-D-glucose, and constitutes roughly 5% of the milk in almost all mammals.
15156	melibiose transmembrane transporter activity	F	Enables the transfer of melibiose from one side of the membrane to the other. Melibiose is the disaccharide 6-O-alpha-D-galactopyranosyl-D-glucose and occurs as a constituent of the trisaccharide raffinose or in the exudates and nectaries of a number of plants.
15157	oligosaccharide transmembrane transporter activity	F	Enables the transfer of oligosaccharide from one side of the membrane to the other.
15158	raffinose transmembrane transporter activity	F	Enables the transfer of raffinose from one side of the membrane to the other. Raffinose occurs in plants almost as commonly as sucrose and is present in cereal grains, cotton seeds, and many legumes. It is synthesized from sucrose by transfer of a galactopyranoside from myo-inositol.
15159	polysaccharide transmembrane transporter activity	F	Enables the transfer of polysaccharides from one side of the membrane to the other. A polysaccharide is a polymer of many (typically more than 10) monosaccharide residues linked glycosidically.
15160	beta-glucan transmembrane transporter activity	F	Enables the transfer of beta-glucans from one side of the membrane to the other. Beta-glucans are compounds composed of glucose residues linked by beta-glucosidic bonds.
15161	capsular polysaccharide transmembrane transporter activity	F	Catalysis of the transfer of capsular-polysaccharides from one side of the membrane to the other. Capsular polysaccharides make up the capsule, a protective structure surrounding some species of bacteria and fungi.
15162	teichoic acid transmembrane transporter activity	F	Enables the transfer of teichoic acid from one side of the membrane to the other. Teichoic acid is any polymer occurring in the cell wall, membrane or capsule of Gram-positive bacteria and containing chains of glycerol phosphate or ribitol phosphate residues.
15164	glucuronoside transmembrane transporter activity	F	Enables the transfer of a glucuronosides from one side of the membrane to the other. Glucuronosides are any compound formed by combination of glycosidic linkage of a hydroxy compound (e.g. an alcohol or a saccharide) with the anomeric carbon atom of glucuronate.
15165	pyrimidine nucleotide-sugar transmembrane transporter activity	F	Enables the transfer of a pyrimidine nucleotide-sugar from one side of the membrane to the other. Pyrimidine nucleotide-sugars are pyrimidine nucleotides in glycosidic linkage with a monosaccharide or monosaccharide derivative.
15166	polyol transmembrane transporter activity	F	Enables the transfer of a polyol from one side of the membrane to the other. A polyol is any polyhydric alcohol.
15167	arabitol transmembrane transporter activity	F	Enables the transfer of an arabitol from one side of the membrane to the other. Arabitol is the pentitol derived from arabinose or lyxose by reduction of the aldehyde group. The D enantiomer is present in lichens and mushrooms.
15168	glycerol transmembrane transporter activity	F	Enables the transfer of glycerol from one side of the membrane to the other. Glycerol is 1,2,3-propanetriol, a sweet, hygroscopic, viscous liquid, widely distributed in nature as a constituent of many lipids.
15169	glycerol-3-phosphate transmembrane transporter activity	F	Enables the transfer of glycerol-3-phosphate from one side of the membrane to the other. Glycerol-3-phosphate is a phosphoric monoester of glycerol.
15170	propanediol transmembrane transporter activity	F	Enables the transfer of propanediol from one side of the membrane to the other. Propanediol is a sweet colorless, viscous, hygroscopic liquid used as an antifreeze and in brake fluid; it is also as a humectant in cosmetics and personal care items, although it can be absorbed through the skin with harmful effects.
15171	amino acid transmembrane transporter activity	F	Enables the transfer of amino acids from one side of a membrane to the other. Amino acids are organic molecules that contain an amino group and a carboxyl group.
15172	acidic amino acid transmembrane transporter activity	F	Enables the transfer of acidic amino acids from one side of a membrane to the other. Acidic amino acids have a pH below 7.
15173	aromatic amino acid transmembrane transporter activity	F	Enables the transfer of aromatic amino acids from one side of a membrane to the other. Aromatic amino acids have an aromatic ring.
15174	basic amino acid transmembrane transporter activity	F	Catalysis of the transfer of basic amino acids from one side of a membrane to the other. Basic amino acids have a pH above 7.
15175	neutral amino acid transmembrane transporter activity	F	Catalysis of the transfer of neutral amino acids from one side of a membrane to the other. Neutral amino acids have a pH of 7.
15179	L-amino acid transmembrane transporter activity	F	Enables the transfer of an L-amino acid from one side of a membrane to the other. L-amino acids are the L-enantiomers of amino acids.
15180	L-alanine transmembrane transporter activity	F	Enables the transfer of L-alanine from one side of a membrane to the other. L-alanine is the L-enantiomer of 2-aminopropanoic acid.
15181	arginine transmembrane transporter activity	F	Enables the stereospecific transfer of arginine, 2-amino-5-guanidinopentanoic acid, across a biological membrane.
15182	L-asparagine transmembrane transporter activity	F	Enables the transfer of L-asparagine from one side of a membrane to the other. L-asparagine is the L-enantiomer of alpha-aminosuccinamic acid.
15183	L-aspartate transmembrane transporter activity	F	Enables the transfer of L-aspartate from one side of a membrane to the other. L-aspartate is the anion derived from aspartic acid.
15184	L-cystine transmembrane transporter activity	F	Enables the transfer of L-cystine from one side of a membrane to the other.
15185	gamma-aminobutyric acid transmembrane transporter activity	F	Enables the transfer of gamma-aminobutyric acid from one side of a membrane to the other. Gamma-aminobutyric acid is 4-aminobutyrate (GABA).
15186	L-glutamine transmembrane transporter activity	F	Enables the transfer of L-glutamine from one side of a membrane to the other. L-glutamine is 2-amino-4-carbamoylbutanoic acid.
15187	glycine transmembrane transporter activity	F	Enables the transfer of glycine from one side of a membrane to the other. Glycine is aminoethanoic acid.
15188	L-isoleucine transmembrane transporter activity	F	Enables the transfer of L-isoleucine from one side of a membrane to the other. L-isoleucine is (2R*,3R*)-2-amino-3-methylpentanoic acid.
15189	L-lysine transmembrane transporter activity	F	Enables the transfer of L-lysine from one side of a membrane to the other. L-lysine is 2,6-diaminohexanoic acid.
15190	L-leucine transmembrane transporter activity	F	Enables the transfer of L-leucine from one side of a membrane to the other. L-leucine is 2-amino-4-methylpentanoic acid.
15191	L-methionine transmembrane transporter activity	F	Enables the transfer of L-methionine from one side of a membrane to the other. L-methionine is 2-amino-4-(methylthio)butanoic acid.
15192	L-phenylalanine transmembrane transporter activity	F	Enables the transfer of L-phenylalanine from one side of a membrane to the other. L-phenylalanine is 2-amino-3-phenylpropanoic acid.
15193	L-proline transmembrane transporter activity	F	Enables the transfer of L-proline from one side of a membrane to the other. L-proline is pyrrolidine-2-carboxylic acid.
15194	L-serine transmembrane transporter activity	F	Enables the transfer of L-serine from one side of a membrane to the other. L-serine is the L-enantiomer of 2-amino-3-hydroxypropanoic acid.
15195	L-threonine transmembrane transporter activity	F	Enables the transfer of L-threonine from one side of a membrane to the other. L-threonine is (2R*,3S*)-2-amino-3-hydroxybutanoic acid.
15196	L-tryptophan transmembrane transporter activity	F	Enables the transfer of L-tryptophan from one side of a membrane to the other. Tryptophan is 2-amino-3-(1H-indol-3-yl)propanoic acid.
15197	peptide transporter activity	F	Enables the directed movement of peptides, compounds of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another, into, out of or within a cell, or between cells.
15198	oligopeptide transporter activity	F	Enables the directed movement of oligopeptides into, out of or within a cell, or between cells. Oligopeptides are molecules that contain a small number (2 to 20) of amino-acid residues connected by peptide linkages.
15199	amino-acid betaine transmembrane transporter activity	F	Enables the transfer of betaine, the N-trimethyl derivative of an amino acid, from one side of the membrane to the other.
15200	methylammonium transmembrane transporter activity	F	Enables directed movement of methylammonium, CH3NH2, into, out of or within a cell, or between cells.
15203	polyamine transmembrane transporter activity	F	Enables the transfer of polyamines, organic compounds containing two or more amino groups, from one side of the membrane to the other.
15204	urea transmembrane transporter activity	F	Enables the directed movement of urea cross a membrane into, out of or within a cell, or between cells. Urea is the water soluble compound H2N-CO-NH2.
15205	nucleobase transmembrane transporter activity	F	Enables the transfer of a nucleobase, any nitrogenous base that is a constituent of a nucleoside, nucleotide, or nucleic acidfrom one side of a membrane to the other.
15207	adenine transmembrane transporter activity	F	Enables the transfer of adenine, 6-aminopurine, from one side of a membrane to the other.
15208	guanine transmembrane transporter activity	F	Enables the transfer of guanine, 2-amino-6-hydroxypurine, from one side of a membrane to the other.
15209	cytosine transmembrane transporter activity	F	Enables the transfer of cytosine, 4-amino-2-hydroxypyrimidine from one side of a membrane to the other.
15210	uracil transmembrane transporter activity	F	Enables the transfer of uracil, 2,4-dioxopyrimidine, from one side of a membrane to the other.
15211	purine nucleoside transmembrane transporter activity	F	Enables the transfer of a purine nucleoside, a purine base covalently bonded to a ribose or deoxyribose sugar, from one side of a membrane to the other.
15212	cytidine transmembrane transporter activity	F	Enables the transfer of cytidine, cytosine riboside, from one side of a membrane to the other.
15213	uridine transmembrane transporter activity	F	Enables the transfer of uridine, uracil riboside, from one side of a membrane to the other.
15214	pyrimidine nucleoside transmembrane transporter activity	F	Enables the transfer of a pyrimidine nucleoside, a pyrimidine base covalently bonded to a ribose or deoxyribose sugar from one side of a membrane to the other.
15215	nucleotide transmembrane transporter activity	F	Enables the transfer of a nucleotide, any compound consisting of a nucleoside that is esterified with (ortho)phosphate, from one side of a membrane to the other.
15216	purine nucleotide transmembrane transporter activity	F	Enables the transfer of a purine nucleotide, any compound consisting of a purine nucleoside esterified with (ortho)phosphate, from one side of a membrane to the other.
15217	ADP transmembrane transporter activity	F	Enables the transfer of ADP, adenosine diphosphate, from one side of a membrane to the other.
15218	pyrimidine nucleotide transmembrane transporter activity	F	Enables the transfer of a pyrimidine nucleotide, any compound consisting of a pyrimidine nucleoside esterified with (ortho)phosphate, from one side of a membrane to the other.
15219	protein-DNA complex transmembrane transporter activity	F	Enables the transfer of protein-DNA complexes from one side of a membrane to the other.
15220	choline transmembrane transporter activity	F	Enables the transfer of choline from one side of the membrane to the other. Choline (2-hydroxyethyltrimethylammonium) is an amino alcohol that occurs widely in living organisms as a constituent of certain types of phospholipids and in the neurotransmitter acetylcholine.
15221	lipopolysaccharide transmembrane transporter activity	F	Enables the transfer of lipopolysaccharides from one side of the membrane to the other. A lipopolysaccharide is any of a group of related, structurally complex components of the outer membrane of Gram-negative bacteria. Lipopolysaccharides consist three covalently linked regions, lipid A, core oligosaccharide, and an O side chain. Lipid A is responsible for the toxicity of the lipopolysaccharide.
15222	serotonin transmembrane transporter activity	F	Enables the transfer of serotonin from one side of the membrane to the other. Serotonin (5-hydroxytryptamine) is a monoamine neurotransmitter occurring in the peripheral and central nervous systems.
15224	biopterin transporter activity	F	Enables the directed movement of biopterin into, out of or within a cell, or between cells. Biopterin is a growth factor for certain protozoans and some insects; it is widely distributed in tissues and functions in a reduced form, tetrahydrobiopterin, as a hydroxylation coenzyme.
15225	biotin transporter activity	F	Enables the directed movement of biotin into, out of or within a cell, or between cells. Biotin is cis-tetrahydro-2-oxothieno(3,4-d)imidazoline-4-valeric acid; the (+) enantiomer is very widely distributed in cells and serves as a carrier in a number of enzymatic beta-carboxylation reactions.
15226	carnitine transmembrane transporter activity	F	Enables the directed movement of carnitine across a membrane. Carnitine is a compound that participates in the transfer of acyl groups across the inner mitochondrial membrane.
15227	acyl carnitine transmembrane transporter activity	F	Enables the directed movement of acyl carnitine across a membrane. Acyl carnitine is the condensation product of a carboxylic acid and carnitine and is the transport form for a fatty acid crossing the mitochondrial membrane.
15228	coenzyme A transmembrane transporter activity	F	Enables the directed movement of coenzyme A across a membrane into, out of or within a cell, or between cells. Coenzyme A, 3'-phosphoadenosine-(5')diphospho(4')pantatheine, is an acyl carrier in many acylation and acyl-transfer reactions in which the intermediate is a thiol ester.
15229	L-ascorbic acid transporter activity	F	Enables the directed movement of L-ascorbate into, out of or within a cell, or between cells. L-ascorbate, (2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2,5-dihydrofuran-3-olate, is vitamin C and has co-factor and anti-oxidant activities in many species.
15230	FAD transmembrane transporter activity	F	Enables the directed movement of flavin-adenine dinucleotide (FAD) across a membrane into, out of or within a cell, or between cells. FAD forms the coenzyme of the prosthetic group of various flavoprotein oxidoreductase enzymes, in which it functions as an electron acceptor by being reversibly converted to its reduced form.
15231	5-formyltetrahydrofolate transporter activity	F	Enables the directed movement of 5-formyltetrahydrofolate, the formylated derivative of tetrahydrofolate, into, out of, within, or between cells.
15232	heme transporter activity	F	Enables the directed movement of heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring, into, out of or within a cell, or between cells.
15233	pantothenate transmembrane transporter activity	F	Enables the directed movement of pantothenate across a membrane. Pantothenate is the anion of pantothenic acid, the amide of beta-alanine and pantoic acid; it is a B complex vitamin that is a constituent of coenzyme A and is distributed ubiquitously in foods.
15234	thiamine transmembrane transporter activity	F	Enables the transfer of thiamine from one side of the membrane to the other. Thiamine is vitamin B1, a water soluble vitamin present in fresh vegetables and meats, especially liver.
15235	cobalamin transporter activity	F	Enables the directed movement of cobalamin (vitamin B12), a water-soluble vitamin characterized by possession of a corrin nucleus containing a cobalt atom, into, out of or within a cell.
15238	drug transmembrane transporter activity	F	Enables the directed movement of a drug from one side of a membrane to the other. A drug is any naturally occurring or synthetic substance, other than a nutrient, that, when administered or applied to an organism, affects the structure or functioning of the organism; in particular, any such substance used in the diagnosis, prevention, or treatment of disease.
15240	amiloride transporter activity	F	Enables the directed movement of amiloride into, out of or within a cell, or between cells. Amiloride is a potent and specific inhibitor of sodium ion entry into cells. It is used as a potassium-sparing diuretic.
15241	aminotriazole transporter activity	F	Enables the directed movement of aminotriazole into, out of or within a cell, or between cells. Aminotriazole is an effective weed killer that also possesses some antithyroid activity.
15242	benomyl transporter activity	F	Enables the directed movement of benomyl into, out of or within a cell, or between cells. Benomyl, methyl 1-(butylcarbamoyl)-2-benzimidazolecarbamate, is a systemic agricultural fungicide used for control of certain fungal diseases of stone fruit.
15243	cycloheximide transporter activity	F	Enables the directed movement of cycloheximide into, out of or within a cell, or between cells. Cycloheximide is an antibiotic produced by Streptomyces which interferes with protein synthesis in eukaryotes.
15244	fluconazole transporter activity	F	Enables the directed movement of fluconazole into, out of or within a cell, or between cells. Fluconazole is an antifungal drug used for oral candidiasis and cryptococcal meningitis; it is still under study for treatment of vaginal candidiasis and other fungal infections.
15245	fatty acid transporter activity	F	Enables the directed movement of fatty acids into, out of or within a cell, or between cells. Fatty acids are aliphatic monocarboxylic acids liberated from naturally occurring fats and oils by hydrolysis.
15246	fatty-acyl group transporter activity	F	Enables the directed movement of a fatty acyl group into, out of or within a cell, or between cells. A fatty acyl group is any acyl group derived from a fatty acid.
15247	aminophospholipid transporter activity	F	Enables the directed movement of aminophospholipids into, out of or within a cell, or between cells. Aminophospholipids contain phosphoric acid as a mono- or diester and an amino (NH2) group.
15248	sterol transporter activity	F	Enables the directed movement of sterols into, out of or within a cell, or between cells. Sterol are steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule.
15250	water channel activity	F	Transport systems of this type enable facilitated diffusion of water (by an energy-independent process) by passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.
15251	ammonium channel activity	F	Enables the facilitated diffusion of ammonium (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.
15252	hydrogen ion channel activity	F	Enables the facilitated diffusion of a hydrogen ion (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.
15254	glycerol channel activity	F	Enables the facilitated diffusion of glycerol (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.
15255	propanediol channel activity	F	Enables the facilitated diffusion of propanediol (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.
15264	methylammonium channel activity	F	Enables the facilitated diffusion of methylammonium (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism. Methylammonium is CH3NH2.
15265	urea channel activity	F	Enables the facilitated diffusion of urea (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.
15266	protein channel activity	F	Enables the energy-independent facilitated diffusion, mediated by passage of proteins through a transmembrane aqueous pore or channel.
15267	channel activity	F	Enables the energy-independent facilitated diffusion, mediated by passage of a solute through a transmembrane aqueous pore or channel. Stereospecificity is not exhibited but this transport may be specific for a particular molecular species or class of molecules.
15269	calcium-activated potassium channel activity	F	Enables the calcium concentration-regulatable energy-independent passage of potassium ions across a lipid bilayer down a concentration gradient.
15271	outward rectifier potassium channel activity	F	Enables the transmembrane transfer of a potassium ion by an outwardly-rectifying voltage-gated channel. An outwardly rectifying current-voltage relation is one where at any given driving force the outward flow of K+ ions exceeds the inward flow for the opposite driving force.
15272	ATP-activated inward rectifier potassium channel activity	F	Enables the transmembrane transfer of a potassium ion by an inwardly-rectifying voltage-gated channel, where the inward rectification is due to a voltage-dependent block of the channel pore by ATP. An inwardly rectifying current-voltage relation is one where at any given driving force the inward flow of K+ ions exceeds the outward flow for the opposite driving force.
15274	organellar voltage-gated chloride channel activity	F	Enables the transmembrane transfer of a chloride ion by a voltage-gated channel. The membrane is an organellar membrane.
15275	stretch-activated, cation-selective, calcium channel activity	F	Enables the transmembrane transfer of a calcium ion by a channel that opens in response to a mechanical stress in the form of stretching.
15276	ligand-gated ion channel activity	F	Enables the transmembrane transfer of an ion by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts.
15277	kainate selective glutamate receptor activity	F	An ionotropic glutamate receptor activity that exhibits fast gating by glutamate, acts by opening a cation channel permeable to sodium and potassium, and for which kainate is an agonist.
15278	calcium-release channel activity	F	Enables the transmembrane transfer of a calcium ion from intracellular stores by a channel that opens when a specific intracellular ligand has been bound by the channel complex or one of its constituent parts.
15279	store-operated calcium channel activity	F	A ligand-gated ion channel activity which transports calcium in response to emptying of intracellular calcium stores.
15280	ligand-gated sodium channel activity	F	Enables the transmembrane transfer of a sodium ion by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts.
15284	fructose uniporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: fructose(out) = fructose(in).
15288	porin activity	F	Catalysis of the transfer of substances, sized less than 1000 Da, from one side of the membrane to the other. The transmembrane portions of porins consist exclusively of beta-strands which form a beta-barrel. They are found in the outer membranes of Gram-negative bacteria, mitochondria, plastids and possibly acid-fast Gram-positive bacteria.
15291	secondary active transmembrane transporter activity	F	Catalysis of the transfer of a solute from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy, not direct ATP coupling. Chemiosmotic sources of energy include uniport, symport or antiport.
15292	uniporter activity	F	Catalysis of the transport of a single molecular species across a membrane; transport is independent of the movement of any other molecular species.
15293	symporter activity	F	Enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported together in the same direction in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy.
15294	solute:cation symporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: solute(out) + cation(out) = solute(in) + cation(in).
15295	solute:proton symporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: solute(out) + H+(out) = solute(in) + H+(in).
15296	anion:cation symporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: anion(out) + cation(out) = anion(in) + cation(in).
15297	antiporter activity	F	Enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported in opposite directions in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy. The reaction is: solute A(out) + solute B(in) = solute A(in) + solute B(out).
15298	solute:cation antiporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: solute(out) + cation(in) = solute(in) + cation(out).
15299	solute:proton antiporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: solute(out) + H+(in) = solute(in) + H+(out).
15301	anion:anion antiporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: anion A(out) + anion B(in) = anion A(in) + anion B(out).
15304	glucose uniporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucose(out) = glucose(in).
15306	sialate:cation symporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sialate(out) + cation(out) = sialate(in) + cation(in).
15307	drug:proton antiporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + drug(in) = H+(in) + drug(out).
15308	amiloride:proton antiporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + amiloride(in) = H+(in) + amiloride(out).
15309	cycloheximide:proton antiporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + cycloheximide(in) = H+(in) + cycloheximide(out).
15310	benomyl:proton antiporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + benomyl(in) = H+(in) + benomyl(out).
15311	monoamine:proton antiporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + monoamine(in) = H+(in) + monoamine(out).
15312	polyamine:proton antiporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + polyamine(in) = H+(in) + polyamine(out).
15313	fluconazole:proton antiporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + fluconazole(in) = H+(in) + fluconazole(out).
15314	aminotriazole:proton antiporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + aminotriazole(in) = H+(in) + aminotriazole(out).
15315	organophosphate:inorganic phosphate antiporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: organophosphate(out) + inorganic phosphate(in) = organophosphate(in) + inorganic phosphate(out).
15317	phosphate:proton symporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: phosphate(out) + H+(out) = phosphate(in) + H+(in).
15318	inorganic solute uptake transmembrane transporter activity	F	Enables the transfer of an inorganic solute from the outside of a cell to the inside of the cell across a membrane.
15319	sodium:inorganic phosphate symporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Na+(out) + inorganic phosphate(out) = Na+(in) + inorganic phosphate(in).
15320	phosphate ion carrier activity	F	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: phosphate (cyt) + H+ (cyt) = phosphate (mitochondrion) + H+ (mitochondrion).
15321	sodium-dependent phosphate transmembrane transporter activity	F	Enables the transfer of phosphate (PO4 3-) ions from one side of a membrane to the other, requiring sodium ions.
15322	secondary active oligopeptide transmembrane transporter activity	F	Catalysis of the transfer of an oligopeptide or oligopeptides from one side of the membrane to the other, up the solute's concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction.
15324	peptide-acetyl-CoA secondary active transmembrane transporter activity	F	Catalysis of the transfer of peptide-acetyl-CoA from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Chemiosmotic sources of energy include uniport, symport or antiport.
15325	acetyl-CoA:CoA antiporter activity	F	Catalysis of the reaction: acetyl-CoA(out) + CoA(in) = acetyl-CoA(in) + CoA(out).
15327	cystine:glutamate antiporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: cystine(out) + glutamate(in) = cystine(in) + glutamate(out).
15328	cystine secondary active transmembrane transporter activity	F	Catalysis of the transfer of cystine from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Chemiosmotic sources of energy include uniport, symport or antiport.
15330	high-affinity glutamine transmembrane transporter activity	F	Catalysis of the high affinity transfer of glutamine from one side of the membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.
15333	peptide:proton symporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: peptide(out) + H+(out) = peptide(in) + H+(in). Catalysis of the transfer of a peptide from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by hydrogen ion movement.
15334	high-affinity oligopeptide transporter activity	F	Catalysis of the transfer of oligopeptide from one side of the membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations. Oligopeptides are molecules that contain a small number (2 to 20) of amino-acid residues connected by peptide linkages.
15341	zinc efflux active transmembrane transporter activity	F	Catalysis of the transfer of a zinc ion or zinc ions from the inside of the cell to the outside of the cell across a membrane: Zn2+(out) = Zn2+(in). The activity is driven by proton motive force.
15343	siderophore transmembrane transporter activity	F	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: siderophore-iron(out) + H+(out) = siderophore-iron(in) + H+(in).
15344	siderophore uptake transmembrane transporter activity	F	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: siderophore-iron(ferrioxamine)(out) + H+(out) = siderophore-iron(ferrioxamine)(in) + H+(in).
15345	ferric enterobactin:proton symporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ferric enterobactin(out) + H+(out) = ferric enterobactin(in) + H+(in).
15346	ferric triacetylfusarinine C:proton symporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ferric triacetylfusarinine C(out) + H+(out) = ferric triacetylfusarinine C(in) + H+(in).
15347	sodium-independent organic anion transmembrane transporter activity	F	Catalysis of the transfer of organic anions from one side of a membrane to the other, in a sodium independent manner.
15349	thyroid hormone transmembrane transporter activity	F	Enables the transfer of thyroid hormones from one side of the membrane to the other. Thyroid hormone are any of the compounds secreted by the thyroid gland, largely thyroxine and triiodothyronine.
15350	methotrexate transporter activity	F	Enables the directed movement of methotrexate, 4-amino-10-methylformic acid, into, out of or within a cell, or between cells. Methotrexate is a folic acid analogue and a potent competitive inhibitor of dihydrofolate reductase.
15351	bilirubin secondary active transmembrane transporter activity	F	Catalysis of the transfer of bilirubin from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Chemiosmotic sources of energy include uniport, symport or antiport.
15352	secondary active sterol transmembrane transporter activity	F	Catalysis of the transfer of sterol from one side of the membrane to the other, up the solute's concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction.
15355	secondary active monocarboxylate transmembrane transporter activity	F	Catalysis of the movement of a monocarboxylate, any compound containing a single carboxyl group (COOH or COO-), by uniport, symport or antiport across a membrane by a carrier-mediated mechanism.
15360	acetate:proton symporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: acetate(out) + H+(out) = acetate(in) + H+(in).
15361	low-affinity sodium:dicarboxylate symporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: dicarboxylate(out) + Na+(out) = dicarboxylate(in) + Na+(in). In low-affinity transport the transporter is able to bind the solute only if it is present at very high concentrations.
15362	high-affinity sodium:dicarboxylate symporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: dicarboxylate(out) + Na+(out) = dicarboxylate(in) + Na+(in). In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.
15364	dicarboxylate:inorganic phosphate antiporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: dicarboxylate(out) + inorganic phosphate(in) = dicarboxylate(in) + inorganic phosphate(out).
15366	malate:proton symporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: malate(out) + H+(out) = malate(in) + H+(in).
15367	oxoglutarate:malate antiporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: oxoglutarate(out) + malate(in) = oxoglutarate(in) + malate(out).
15368	calcium:cation antiporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Ca2+(in) + cation(out) = Ca2+(out) + cation(in).
15369	calcium:proton antiporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Ca2+(in) + H+(out) = Ca2+(out) + H+(in).
15370	solute:sodium symporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: solute(out) + Na+(out) = solute(in) + Na+(in).
15371	galactose:sodium symporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: galactose(out) + Na+(out) = glucose(in) + Na+(in).
15373	monovalent anion:sodium symporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: monovalent anion(out) + Na+(out) = monovalent anion(in) + Na+(in).
15374	neutral, basic amino acid:sodium:chloride symporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: neutral/basic amino acid(out) + Na+(out) + Cl-(out) = neutral/basic amino acid(in) + Na+(in) + Cl-(in).
15375	glycine:sodium symporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glycine(out) + Na+(out) = glycine(in) + Na+(in).
15377	cation:chloride symporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: cation(out) + Cl-(out) = cation(in) + Cl-(in).
15378	sodium:chloride symporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Na+(out) + Cl-(out) = Na+(in) + Cl-(in).
15379	potassium:chloride symporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: K+(out) + Cl-(out) = K+(in) + Cl-(in).
15381	high-affinity sulfate transmembrane transporter activity	F	Catalysis of the secondary active high affinity transfer of sulfate from one side of the membrane to the other. Secondary active transport is catalysis of the transfer of a solute from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Chemiosmotic sources of energy include uniport, symport or antiport. In high-affinity transport the transporter is able to bind thesolute even if it is only present at very low concentrations.
15382	sodium:sulfate symporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sulfate(out) + Na+(out) = sulfate(in) + Na+(in).
15383	sulfate:bicarbonate antiporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sulfate(out) + bicarbonate(in) = sulfate(in) + bicarbonate(out).
15385	sodium:proton antiporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Na+(out) + H+(in) = Na+(in) + H+(out).
15386	potassium:proton antiporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: K+(in) + H+(out) = K+(out) + H+(in).
15387	potassium:proton symporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: K+(out) + H+(out) = K+(in) + H+(in).
15388	potassium uptake transmembrane transporter activity	F	Enables the transfer of potassium from the outside of a cell to the inside of the cell across a membrane: K+(out) + energy = K+(in).
15389	pyrimidine- and adenine-specific:sodium symporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: (pyrimidine nucleoside or adenine)(out) + Na+(out) = (pyrimidine nucleoside or adenine)(in) + Na+(in).
15390	purine-specific nucleoside:sodium symporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: purine(out) + Na+(out) = nucleoside(in) + Na+(in).
15391	nucleobase:cation symporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: nucleobase(out) + cation(out) = nucleobase(in) + cation(in).
15394	uridine:hydrogen ion symporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: uridine(out) + H+(out) = uridine(in) + H+(in).
15395	nucleoside transmembrane transporter activity, down a concentration gradient	F	Catalysis of the transfer of a nucleoside, from one side of a membrane to the other, down the concentration gradient.
15398	high-affinity secondary active ammonium transmembrane transporter activity	F	Catalysis of the transfer of ammonium from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Chemiosmotic sources of energy include uniport, symport or antiport. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.
15399	primary active transmembrane transporter activity	F	Catalysis of the transfer of a solute from one side of the membrane to the other, up the solute's concentration gradient, by binding the solute and undergoing a series of conformational changes. Transport works equally well in either direction and is powered by a primary energy source, directly using ATP. Primary energy sources known to be coupled to transport are chemical, electrical and solar sources.
15400	low-affinity secondary active ammonium transmembrane transporter activity	F	Catalysis of the transfer of ammonium from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Chemiosmotic sources of energy include uniport, symport or antiport. In low-affinity transport the transporter is able to bind the solute only if it is present at very high concentrations.
15401	urea:sodium symporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: urea(out) + Na+(out) = urea(in) + Na+(in).
15403	thiamine uptake transmembrane transporter activity	F	Enables the transfer of thiamine from the outside of a cell to the inside across a membrane.
15405	P-P-bond-hydrolysis-driven transmembrane transporter activity	F	Primary active transport of a solute across a membrane, driven by the hydrolysis of the diphosphate bond of inorganic pyrophosphate, ATP, or another nucleoside triphosphate. The transport protein may or may not be transiently phosphorylated, but the substrate is not phosphorylated. Primary active transport is catalysis of the transport of a solute across a membrane, up the solute's concentration gradient, by binding the solute and undergoing a series of conformational changes. Transport works equally well in either direction and is driven by a primary energy source.
15407	monosaccharide-transporting ATPase activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + monosaccharide(out) = ADP + phosphate + monosaccharide(in). Ribose, xylose, arabinose, galactose and methylgalactoside are imported.
15408	ferric-transporting ATPase activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Fe3+(out) = ADP + phosphate + Fe3+(in).
15410	manganese-transporting ATPase activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Mn2+(out) = ADP + phosphate + Mn2+(in).
15411	taurine-transporting ATPase activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + taurine(out) = ADP + phosphate + taurine(in).
15412	ATPase-coupled molybdate transmembrane transporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + molybdate(out) = ADP + phosphate + molybdate(in).
15413	nickel-transporting ATPase activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Ni2+(out) = ADP + phosphate + Ni2+(in).
15414	ATPase-coupled nitrate transmembrane transporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + nitrate(out) = ADP + phosphate + nitrate(in).
15415	ATPase-coupled phosphate ion transmembrane transporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + phosphate(out) = ADP + phosphate + phosphate(in).
15416	ATPase-coupled organic phosphonate transmembrane transporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + phosphonate(out) = ADP + phosphate + phosphonate(in). A phosphonate is any salt, anion, or ester of phosphonic acid (HPO(OH)2).
15417	polyamine-transporting ATPase activity	F	Catalysis of the reaction: ATP + H2O + polyamine(out) = ADP + phosphate + polyamine(in).
15418	quaternary-ammonium-compound-transporting ATPase activity	F	Catalysis of the reaction: ATP + H2O + quaternary amine(out) = ADP + phosphate + quaternary amine(in).
15419	ATPase-coupled sulfate transmembrane transporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + sulfate(out) = ADP + phosphate + sulfate(in).
15420	cobalamin-transporting ATPase activity	F	Catalysis of the reaction: ATP + H2O + cob(III)alamin(out) = ADP + phosphate + cob(III)alamin(in). Cobalamin is also known as vitamin B12.
15421	oligopeptide-transporting ATPase activity	F	Catalysis of the reaction: ATP + H2O + oligopeptide(out) = ADP + phosphate + oligopeptide(in).
15422	oligosaccharide-transporting ATPase activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + oligosaccharide(out) = ADP + phosphate + oligosaccharide(in).
15423	maltose-transporting ATPase activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + maltose(out) = ADP + phosphate + maltose(in).
15424	amino acid-transporting ATPase activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + amino acid(out/in) = ADP + phosphate + amino acid(in/out).
15425	nonpolar-amino acid-transporting ATPase activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + nonpolar amino acid(out) = ADP + phosphate + nonpolar amino acid(in).
15426	polar-amino acid-transporting ATPase activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + polar amino acid(out) = ADP + phosphate + polar amino acid(in).
15430	glycerol-3-phosphate-transporting ATPase activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + glycerol-3-phosphate(out) = ADP + phosphate + glycerol-3-phosphate(in).
15431	glutathione S-conjugate-exporting ATPase activity	F	Catalysis of the reaction: ATP + H2O + glutathione S-conjugate(in) -> ADP + phosphate + glutathione S-conjugate(out).
15432	bile acid-exporting ATPase activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: bile acid(in) + ATP + H2O -> bile acid(out) + ADP + phosphate.
15433	peptide antigen-transporting ATPase activity	F	Catalysis of the reaction: peptide antigen(in) + ATP = peptide antigen(out) + ADP + phosphate.
15434	cadmium-transporting ATPase activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Cd (cytosol) = ADP + phosphate + Cd (vacuole).
15436	capsular-polysaccharide-transporting ATPase activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + capsular polysaccharide(in) = ADP + phosphate + capsular polysaccharide(out).
15437	lipopolysaccharide-transporting ATPase activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + lipopolysaccharide(in) = ADP + phosphate + lipopolysaccharide(out).
15438	teichoic-acid-transporting ATPase activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + teichoic acid(in) = ADP + phosphate + teichoic acid(out).
15439	heme-transporting ATPase activity	F	Catalysis of the reaction: ATP + H2O + heme(in) = ADP + phosphate + heme(out).
15440	peptide-transporting ATPase activity	F	Catalysis of the reaction: ATP + H2O + peptide(in) = ADP + phosphate + peptide(out). Peptides exported include alpha-hemolysin, cyclolysin, colicin V and siderophores from Gram-negative bacteria, and bacteriocin, subtilin, competence factor and pediocin from Gram-positive bacteria.
15441	beta-glucan-transporting ATPase activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + beta-glucan(in) = ADP + phosphate + beta-glucan(out).
15444	magnesium-importing ATPase activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Mg2+(out) -> ADP + phosphate + Mg2+(in).
15445	silver-exporting ATPase activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Ag+(in) -> ADP + phosphate + Ag+(out).
15446	ATPase-coupled arsenite transmembrane transporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + arsenite(in) = ADP + phosphate + arsenite(out).
15450	P-P-bond-hydrolysis-driven protein transmembrane transporter activity	F	Primary active carrier-mediated transport of a protein across a membrane, driven by the hydrolysis of the diphosphate bond of inorganic pyrophosphate, ATP, or another nucleoside triphosphate. The transport protein may or may not be transiently phosphorylated, but the substrate is not phosphorylated.
15451	decarboxylation-driven active transmembrane transporter activity	F	Primary active transport of a solute across a membrane driven by decarboxylation of a cytoplasmic substrate. Primary active transport is catalysis of the transport of a solute across a membrane, up the solute's concentration gradient, by binding the solute and undergoing a series of conformational changes. Transport works equally well in either direction and is driven by a primary energy source.
15452	methyl transfer-driven active transmembrane transporter activity	F	Primary active transport of a solute across a membrane driven by a methyl transfer reaction. Primary active transport is catalysis of the transport of a solute across a membrane, up the solute's concentration gradient, by binding the solute and undergoing a series of conformational changes. Transport works equally well in either direction and is driven by a primary energy source.
15453	oxidoreduction-driven active transmembrane transporter activity	F	Primary active transport of a solute across a membrane, driven by exothermic flow of electrons from a reduced substrate to an oxidized substrate. Primary active transport is catalysis of the transport of a solute across a membrane, up the solute's concentration gradient, by binding the solute and undergoing a series of conformational changes. Transport works equally well in either direction and is driven by a primary energy source.
15454	light-driven active transmembrane transporter activity	F	Primary active transport of a solute across a membrane, driven by light. Primary active transport is catalysis of the transport of a solute across a membrane, up the solute's concentration gradient, by binding the solute and undergoing a series of conformational changes. Transport works equally well in either direction and is driven by a primary energy source.
15459	potassium channel regulator activity	F	Modulates potassium channel activity via direct interaction interaction with a potassium channel (binding or modification).
15462	ATPase-coupled protein transmembrane transporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + protein(out) = ADP + phosphate + protein(in).
15464	acetylcholine receptor activity	F	Combining with acetylcholine and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
15467	G-protein activated inward rectifier potassium channel activity	F	Enables the transmembrane transfer of a potassium ion by an inwardly-rectifying voltage-gated channel, where the inward rectification is due to a voltage-dependent block of the channel pore by a G protein. An inwardly rectifying current-voltage relation is one where at any given driving force the inward flow of K+ ions exceeds the outward flow for the opposite driving force.
15471	nucleoside-specific channel forming porin activity	F	Enables the energy independent passage of nucleoside, sized less than 1000 Da, across a membrane. The transmembrane portions of porins consist exclusively of beta-strands which form a beta-barrel. They are found in the outer membranes of Gram-negative bacteria, mitochondria, plastids and possibly acid-fast Gram-positive bacteria.
15473	fimbrial usher porin activity	F	A porin that acts in the assembly of fimbria together with fimbrial chaperone.
15474	autotransporter activity	F	Transports a passenger protein from the periplasm to the external milieu; the passenger protein and the porin are the N- and C-terminal regions of the same protein, respectively.
15475	adhesin autotransporter activity	F	Catalysis of the transfer of adhesin from the periplasm to the external milieu; the adhesin and the porin are the N- and C-terminal regions of the same protein, respectively.
15476	hemaglutinin autotransporter activity	F	Catalysis of the transfer of hemaglutinin from the periplasm to the external milieu; the hemaglutinin and the porin are the N- and C-terminal regions of the same protein, respectively.
15478	oligosaccharide transporting porin activity	F	Catalysis of the transfer of oligosaccharide, sized less than 1000 Da, from one side of the membrane to the other. The transmembrane portions of porins consist exclusively of beta-strands which form a beta-barrel. They are found in the outer membranes of Gram-negative bacteria, mitochondria, plastids and possibly acid-fast Gram-positive bacteria.
15481	maltose transporting porin activity	F	Catalysis of the transfer of maltose from one side of the membrane to the other. Maltose is the disaccharide 4-O-alpha-D-glucopyranosyl-D-glucopyranose, an intermediate in the enzymatic breakdown of glycogen and starch. This transporter is a porin so enables the energy independent passage of substances, sized less than 1000 Da, across a membrane. The transmembrane portions of porins consist exclusively of beta-strands which form a beta-barrel. They are found in the outer membranes of Gram-negative bacteria, mitochondria, plastids and possibly acid-fast Gram-positive bacteria.
15483	long-chain fatty acid transporting porin activity	F	Enables the transfer of long-chain fatty acids from one side of the membrane to the other. A long-chain fatty acid is a fatty acid with a chain length between C13 and C22. This transporter is a porin and so enables the energy independent passage of substances, sized less than 1000 Da, across a membrane. The transmembrane portions of porins consist exclusively of beta-strands which form a beta-barrel. They are found in the outer membranes of Gram-negative bacteria, mitochondria, plastids and possibly acid-fast Gram-positive bacteria.
15485	cholesterol binding	F	Interacting selectively and non-covalently with cholesterol (cholest-5-en-3-beta-ol); the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones.
15486	glycoside-pentoside-hexuronide:cation symporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: (glycoside, pentoside or hexuronide)(out) + monovalent cation(out) = (glycoside, pentoside or hexuronide)(in) + monovalent cation(in). The cation is Na+, Li+ or H+.
15487	melibiose:monovalent cation symporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: melibiose(out) + monovalent cation(out) = melibiose(in) + monovalent cation(in).
15488	glucuronide:monovalent cation symporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucuronide(out) + monovalent cation(out) = glucuronide(in) + monovalent cation(in).
15489	putrescine transmembrane transporter activity	F	Enables the transfer of putrescine from one side of the membrane to the other. Putrescine is 1,4-diaminobutane, the polyamine formed by decarboxylation of ornithine and the metabolic precursor of spermidine and spermine.
15490	cadaverine transmembrane transporter activity	F	Enables the transfer of cadaverine, 1,5-pentanediamine, from one side of the membrane to the other.
15491	cation:cation antiporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: cation A(out) + cation B(in) = cation A(in) + cation B(out).
15492	phenylalanine:proton symporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: phenylalanine(out) + H+(out) = phenylalanine(in) + H+(in).
15493	lysine:proton symporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: lysine(out) + H+(out) = lysine(in) + H+(in).
15494	aromatic amino acid:proton symporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: aromatic amino acid(out) + H+(out) = aromatic amino acid(in) + H+(in).
15495	gamma-aminobutyric acid:proton symporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: gamma-aminobutyric acid(out) + H+(out) = gamma-aminobutyric acid(in) + H+(in).
15496	putrescine:ornithine antiporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: putrescine(out) + ornithine(in) = putrescine(in) + ornithine(out).
15498	pantothenate:sodium symporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: pantothenate(out) + Na+(out) = pantothenate(in) + Na+(in).
15499	formate transmembrane transporter activity	F	Enables the transfer of formate from one side of the membrane to the other. Formate is also known as methanoate, the anion HCOO- derived from methanoic (formic) acid.
15501	glutamate:sodium symporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glutamate(out) + Na+(out) = glutamate(in) + Na+(in).
15503	glutathione-regulated potassium exporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: K+(in) + H+(out) = K+(out) + H+(in), where glutathione maintains the closed state.
15504	cytosine:hydrogen ion symporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: cytosine(out) + H+(out) = cytosine(in) + H+(in).
15505	uracil:cation symporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: uracil(out) + cation(out) = uracil(in) + cation(in).
15506	nucleoside:proton symporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: nucleoside(out) + H+(out) = nucleoside(in) + H+(in).
15513	nitrite uptake transmembrane transporter activity	F	Enables the transfer of nitrite from the outside of a cell to the inside of the cell across a membrane.
15514	nitrite efflux transmembrane transporter activity	F	Enables the transfer of nitrite from the inside of the cell to the outside of the cell across a membrane.
15515	citrate:succinate antiporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: citrate(out) + succinate(in) = citrate(in) + succinate(out).
15516	tartrate:succinate antiporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: tartrate(out) + succinate(in) = tartrate(in) + succinate(out).
15517	galactose:proton symporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: galactose(out) + H+(out) = galactose(in) + H+(in).
15518	arabinose:proton symporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: arabinose(out) + H+(out) = arabinose(in) + H+(in).
15519	D-xylose:proton symporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: D-xylose(out) + H+(out) = D-xylose(in) + H+(in).
15520	tetracycline:proton antiporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + tetracycline(in) = H+(in) + tetracycline(out).
15522	hydrophobic uncoupler:proton antiporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: hydrophobic uncoupler(in) + H+(out) = hydrophobic uncoupler(out) + H+(in). Hydrophobic uncouplers include CCCP, benzalkonium and SDS.
15523	arabinose efflux transmembrane transporter activity	F	Catalysis of the transfer of arabinose from the inside of the cell to the outside of the cell across a membrane: H+(out) + arabinose(in) = H+(in) + arabinose(out).
15526	hexose-phosphate:inorganic phosphate antiporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: hexose phosphate(out) + inorganic phosphate(in) = hexose phosphate(in) + inorganic phosphate(out).
15527	glycerol-phosphate:inorganic phosphate antiporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glycerol phosphate(out) + inorganic phosphate(in) = glycerol phosphate(in) + inorganic phosphate(out).
15528	lactose:proton symporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: lactose(out) + H+(out) = lactose(in) + H+(in).
15529	raffinose:proton symporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: raffinose(out) + H+(out) = raffinose(in) + H+(in).
15530	shikimate transmembrane transporter activity	F	Enables the transfer of shikimate from one side of the membrane to the other. Shikimate is an important intermediate in the biosynthesis of aromatic amino acids.
15531	citrate:proton symporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: citrate(out) + H+(out) = citrate(in) + H+(in).
15532	alpha-ketoglutarate:proton symporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: alpha-ketoglutarate(out) + H+(out) = alpha-ketoglutarate(in) + H+(in).
15533	shikimate:proton symporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: shikimate(out) + H+(out) = shikimate(in) + H+(in).
15535	fucose:proton symporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: fucose(out) + H+(out) = fucose(in) + H+(in).
15537	xanthosine:hydrogen ion symporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: xanthosine(out) + H+(out) = xanthosine(in) + H+(in).
15538	sialic acid:proton symporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sialate(out) + H+(out) = sialate(in) + H+(in).
15539	hexuronate:cation symporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: hexuronate(out) + cation(out) = hexuronate(in) + cation(in). The hexuronate may be glucuronate or galacturonate.
15540	3-hydroxyphenyl propionate:hydrogen ion symporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: 3-hydroxyphenyl propionate(out) + H+(out) = 3-hydroxyphenyl propionate(in) + H+(in).
15541	secondary active cyanate uptake transmembrane transporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: cyanate(out) = cyanate(in).
15542	sugar efflux transmembrane transporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sugar(in) = sugar(out).
15544	phenyl propionate uptake uniporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: phenyl propionate(out) = phenyl propionate(in).
15545	bicyclomycin transporter activity	F	Enables the directed movement of bicyclomycin into, out of or within a cell, or between cells. Bicyclomycin (or bicozamycin) is an antibacterial drug often used as a livestock feed additive.
15546	sulfathiazole transmembrane transporter activity	F	Enables the directed movement of sulfathiazole across a membrane. Sulfathiazole is an antibacterial agent of the sulfonamide group.
15547	nalidixic acid transporter activity	F	Enables the directed movement of nalidixic acid into, out of or within a cell, or between cells. Nalidixic acid is a synthetic antibiotic that interferes with DNA gyrase and inhibits prokaryotic replication.
15548	organomercurial transporter activity	F	Enables the directed movement of organomercurial compounds into, out of or within a cell, or between cells. Organomercurial substances are any organic compound containing a mercury atom.
15549	carbonyl cyanide m-chlorophenylhydrazone transporter activity	F	Enables the directed movement of carbonyl cyanide m-chlorophenylhydrazone into, out of or within a cell, or between cells. Carbonyl cyanide m-chlorophenylhydrazone is a proton ionophore, commonly used as an uncoupling agent and inhibitor of photosynthesis because of its effects on mitochondrial and chloroplast membranes.
15550	galacturonate transmembrane transporter activity	F	Enables the transfer of galacturonate from one side of the membrane to the other. Galacturonate is the uronic acid formally derived from galactose by oxidation of the hydroxymethylene group at C-6 to a carboxyl group.
15551	3-hydroxyphenyl propanoate transmembrane transporter activity	F	Enables the transfer of 3-hydroxyphenyl propanoate from one side of the membrane to the other.
15552	propionate transmembrane transporter activity	F	Enables the transfer of propionate from one side of the membrane to the other. Propionate (or propanoate) is the organic acid CH3-CH2-COOH.
15553	xanthosine transmembrane transporter activity	F	Enables the transfer of xanthosine, xanthine riboside, from one side of a membrane to the other.
15554	tartrate transmembrane transporter activity	F	Enables the transfer of tartrate from one side of the membrane to the other. Tartrate is the anion of 2,3-dihydroxybutanedioic acid, one of the aldaric acids. The L(+) enantiomer occurs widely in plants, especially in grape juice, and in fungi and bacteria.
15556	C4-dicarboxylate transmembrane transporter activity	F	Enables the transfer of C4-dicarboxylate from one side of the membrane to the other.
15557	arginine targeting transmembrane transporter activity	F	Enables the directed movement of fully folded proteins into, out of or within a cell, or between cells, by targeting the proteins to the transporter via a specialized N-terminal twin arginine signal peptide.
15558	p-aminobenzoyl-glutamate uptake transmembrane transporter activity	F	Enables the transfer of p-aminobenzoyl-glutamate from the outside of a cell to the inside of the cell across a membrane.
15561	rhamnose:proton symporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: rhamnose(out) + H+(out) = rhamnose(in) + H+(in).
15562	efflux transmembrane transporter activity	F	Enables the transfer of a specific substance or related group of substances from the inside of the cell to the outside of the cell across a membrane.
15563	uptake transmembrane transporter activity	F	Enables the transfer of a specific substance or related group of substances from the outside of a cell to the inside across a membrane.
15565	threonine efflux transmembrane transporter activity	F	Catalysis of the transfer of threonine from the inside of the cell to the outside of the cell across a membrane.
15566	acriflavine transporter activity	F	Enables the directed movement of acriflavin into, out of or within a cell, or between cells. Acriflavin is a fluorescent dye used as a local antiseptic and also as a biological stain. It intercalates into nucleic acids thereby inhibiting bacterial and viral replication.
15567	alkane transporter activity	F	Enables the directed movement of alkanes into, out of or within a cell, or between cells. Alkanes are saturated aliphatic hydrocarbon compounds.
15568	L-idonate transmembrane transporter activity	F	Enables the transfer of L-idonate from one side of the membrane to the other. L-idonate is an aldonic acid derived from L-idose, an aldohexose which is epimeric with D-glucose.
15569	p-aminobenzoyl-glutamate transmembrane transporter activity	F	Enables the transfer of p-aminobenzoyl-glutamate from one side of a membrane to the other. p-aminobenzoyl-glutamate is the anion of p-aminobenzoyl-glutamic acid.
15571	N-acetylgalactosamine transmembrane transporter activity	F	Enables the transfer of N-acetylgalactosamine from one side of the membrane to the other. N-acetylgalactosamine, 2-acetamido-2-deoxygalactopyranose, is the n-acetyl derivative of galactosamine.
15572	N-acetylglucosamine transmembrane transporter activity	F	Enables the transfer of N-acetylglucosamine from one side of the membrane to the other. The D isomer of N-acetylglucosamine is a common structural unit of glycoproteins in plants, bacteria and animals; it is often the terminal sugar of an oligosaccharide group of a glycoprotein.
15573	beta-glucoside transmembrane transporter activity	F	Enables the transfer of beta-glucosides from one side of the membrane to the other. Beta-glucosides are glycosides in which the sugar group is a glucose residue, and the anomeric carbon of the bond is in a beta configuration.
15574	trehalose transmembrane transporter activity	F	Enables the transfer of trehalose from one side of the membrane to the other. Trehalose is the disaccharide alpha-D-glucopyranosyl-alpha-D-glucopyranoside that acts of a reserve carbohydrate in certain fungi, algae and lichens.
15575	mannitol transmembrane transporter activity	F	Enables the transfer of mannitol from one side of the membrane to the other. Mannitol is the alditol derived from D-mannose by reduction of the aldehyde group.
15576	sorbitol transmembrane transporter activity	F	Enables the transfer of sorbitol from one side of the membrane to the other. Sorbitol, also known as glucitol, is the hexitol derived by the reduction of the aldehyde group of glucose.
15577	galactitol transmembrane transporter activity	F	Enables the transfer of a galactitol from one side of the membrane to the other. Galactitol is the hexitol derived by the reduction of the aldehyde group of either D- or L-galactose.
15578	mannose transmembrane transporter activity	F	Enables the transfer of mannose from one side of the membrane to the other. Mannose is the aldohexose manno-hexose, the C-2 epimer of glucose. The D-(+)-form is widely distributed in mannans and hemicelluloses and is of major importance in the core oligosaccharide of N-linked oligosaccharides of glycoproteins.
15591	D-ribose transmembrane transporter activity	F	Enables the transfer of D-ribose from one side of the membrane to the other. As beta-D-ribofuranose, D-ribose forms the glycose group of all ribonucleosides, ribonucleotides and ribonucleic acids, and also of ribose phosphates, various glycosides, some coenzymes and some forms of vitamin B12.
15592	methylgalactoside transmembrane transporter activity	F	Enables the transfer of methylgalactoside from one side of the membrane to the other. Methylgalactoside is a compound in which the H of the OH group on carbon-1 of galactose is replaced by a methyl group.
15593	allose transmembrane transporter activity	F	Enables the transfer of allose from one side of the membrane to the other. Allose is an aldohexose similar to glucose, differing only in the configuration of the hydroxyl group of C-3.
15594	putrescine-importing ATPase activity	F	Catalysis of the reaction: ATP + H2O + putrescine(out) -> ADP + phosphate + putrescine(in).
15595	spermidine-importing ATPase activity	F	Catalysis of the reaction: ATP + H2O + spermidine(out) -> ADP + phosphate + spermidine(in).
15598	arginine-importing ATPase activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + arginine(out) -> ADP + phosphate + arginine(in).
15599	glutamine-importing ATPase activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + glutamine(out) -> ADP + phosphate + glutamine(in).
15603	iron chelate transmembrane transporter activity	F	Enables the transfer of an iron chelate from one side of a membrane to the other. An iron chelate is a heterocyclic compound having a metal ion attached by coordinate bonds to at least two nonmetal ions.
15604	organic phosphonate transmembrane transporter activity	F	Enables the transfer of phosphonate from one side of a membrane to the other. A phosphonate is any salt, anion, or ester of phosphonic acid (HPO(OH)2).
15605	organophosphate ester transmembrane transporter activity	F	Enables the transfer of organophosphate esters from one side of a membrane to the other. Organophosphate esters are small organic molecules containing phosphate ester bonds.
15606	spermidine transmembrane transporter activity	F	Enables the transfer of spermidine, N-(3-aminopropyl)-1,4-diaminobutane, from one side of the membrane to the other.
15607	fatty-acyl-CoA transporter activity	F	Enables the directed movement of a fatty acyl CoA group into, out of or within a cell, or between cells. A fatty acyl CoA group is any acyl group derived from a fatty acid with a coenzyme A group attached to it.
15608	carbohydrate-importing ATPase activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + carbohydrate(out) -> ADP + phosphate + carbohydrate(in).
15609	maltooligosaccharide-importing ATPase activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + maltooligosaccharide(out) -> ADP + phosphate + maltooligosaccharide(in).
15610	glycerol phosphate-importing ATPase activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + glycerol-phosphate(out) -> ADP + phosphate + glycerol-phosphate(in).
15611	D-ribose-importing ATPase activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + D-ribose(out) -> ADP + phosphate + D-ribose(in).
15612	L-arabinose-importing ATPase activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + L-arabinose(out) -> ADP + phosphate + L-arabinose(in).
15614	D-xylose-importing ATPase activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + D-xylose(out) -> ADP + phosphate + D-xylose(in).
15615	D-allose-importing ATPase activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + D-allose(out) -> ADP + phosphate + D-allose(in).
15616	DNA translocase activity	F	Catalysis of the reaction: ATP + H2O = ADP + phosphate, to drive movement along a single- or double-stranded DNA molecule.
15619	thiamine pyrophosphate-transporting ATPase activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + thiamine pyrophosphate(out) = ADP + phosphate + thiamine pyrophosphate(in).
15620	ferric-enterobactin transmembrane transporter activity	F	Catalysis of the transfer of ferric-enterobactin from one side of a membrane to the other.
15621	ferric triacetylfusarinine C transmembrane transporter activity	F	Enables the transfer of ferric triacetylfusarinine C from one side of a membrane to the other.
15622	ferric-hydroxamate transmembrane transporter activity	F	Catalysis of the transfer of ferric-hydroxamate from one side of a membrane to the other.
15623	iron-chelate-transporting ATPase activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + iron chelate(out) = ADP + phosphate + iron chelate(in). Fe-enterobactin, Fe-dicitrate, Fe-hydroxamate and other siderophores are imported.
15624	ferric-enterobactin-transporting ATPase activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + ferric-enterobactin(out) = ADP + phosphate + ferric-enterobactin(in).
15625	ferric-hydroxamate-transporting ATPase activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + ferric-hydroxamate(out) = ADP + phosphate + ferric-hydroxamate(in).
15626	L-diaminopimelate transmembrane transporter activity	F	Catalysis of the transfer of L-diaminopimelate from one side of a membrane to the other. L-diaminopimelate is the L-enantiomer anion of 2,6-diaminoheptanedioic acid.
15627	type II protein secretion system complex	C	A large protein complex, containing 12-15 subunits, that spans the cell envelope of Gram-negative bacteria and mediates the movement of proteins into the extracellular environment. The complex includes a component in the cytoplasm, an inner membrane subcomplex that reaches into the periplasmic compartment and a secretion pore in the outer membrane. Proteins using the Type II pathway are transported across the cytoplasmic membrane by the Sec or Tat complex.
15628	protein secretion by the type II secretion system	P	The process in which proteins are secreted across the outer membrane of Gram-negative bacteria by the type II secretion system. Proteins using this pathway are first translocated across the cytoplasmic membrane via the Sec or Tat pathways.
15629	actin cytoskeleton	C	The part of the cytoskeleton (the internal framework of a cell) composed of actin and associated proteins. Includes actin cytoskeleton-associated complexes.
15630	microtubule cytoskeleton	C	The part of the cytoskeleton (the internal framework of a cell) composed of microtubules and associated proteins.
15631	tubulin binding	F	Interacting selectively and non-covalently with monomeric or multimeric forms of tubulin, including microtubules.
15633	zinc-transporting ATPase activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Zn2+(out) = ADP + phosphate + Zn2+(in).
15634	lipopolysaccharide exporter activity	F	Catalysis of the transfer of lipopolysaccharide from the inside of the cell to the outside of the cell across a membrane. A lipopolysaccharide is any of a group of related, structurally complex components of the outer membrane of Gram-negative bacteria. Lipopolysaccharides consist three covalently linked regions, lipid A, core oligosaccharide, and an O side chain. Lipid A is responsible for the toxicity of the lipopolysaccharide.
15635	short-chain fatty acid transporter activity	F	Enables the directed movement of short-chain fatty acids into, out of or within a cell, or between cells. Short-chain fatty acids are fatty acids with a chain length of less than C6.
15636	short-chain fatty acid uptake transporter activity	F	Enables the directed movement of short-chain fatty acids into a cell or organelle. Short-chain fatty acids are fatty acids with a chain length of less than C6.
15638	microcin uptake transporter activity	F	Enables the transfer of a microcin from the outside of a cell to the inside of the cell across a membrane.
15639	ferrous iron uptake transmembrane transporter activity	F	Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Fe2+(out) + energy = Fe2+(in).
15640	peptidoglycan peptide transporter activity	F	Enables the directed movement of peptidoglycan peptides into, out of or within a cell, or between cells. Peptidoglycan peptides are the oligopeptides found in peptidoglycan networks which cross-link the polysaccharide chains.
15643	toxic substance binding	F	Interacting selectively and non-covalently with a toxic substance, a poisonous substance that causes damage to biological systems.
15645	fatty acid ligase activity	F	Catalysis of the ligation of a fatty acid to an acceptor, coupled to the hydrolysis of ATP.
15647	peptidoglycan transporter activity	F	Enables the directed movement of peptidoglycans, a class of glycoconjugates found in bacterial cell walls, into, out of or within a cell, or between cells.
15648	lipid-linked peptidoglycan transporter activity	F	Enables the directed movement of lipid-linked peptidoglycans into, out of or within a cell, or between cells.
15649	2-keto-3-deoxygluconate:proton symporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: 2-keto-3-deoxygluconate(out) + H+(out) = 2-keto-3-deoxygluconate(in) + H+(in).
15650	lactate:proton symporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: lactate (out) + H+ (out) = lactate (in) + H+ (in).
15651	quaternary ammonium group transmembrane transporter activity	F	Enables the transfer of quaternary ammonium groups from one side of a membrane to the other. Quaternary ammonium groups are any compound that can be regarded as derived from ammonium hydroxide or an ammonium salt by replacement of all four hydrogen atoms of the NH4+ ion by organic groups.
15652	quaternary ammonium group:proton symporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: quaternary ammonium group(out) + H+(out) = quaternary ammonium group(in) + H+(in).
15653	glycine betaine:proton symporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glycine betaine(out) + H+(out) = glycine betaine(in) + H+(in).
15654	tellurite uptake transmembrane transporter activity	F	Enables the transfer of tellurite from the outside of a cell to the inside across a membrane: tellurite(out) + H+(out) = tellurite(in) + H+(in).
15655	alanine:sodium symporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: alanine(out) + Na+(out) = alanine(in) + Na+(in).
15657	branched-chain amino acid:sodium symporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: branched-chain amino acid(out) + cation(out) = branched-chain amino acid(in) + cation(in).
15658	branched-chain amino acid transmembrane transporter activity	F	Enables the transfer of branched-chain amino acids from one side of a membrane to the other. Branched-chain amino acids are amino acids with a branched carbon skeleton without rings.
15659	formate uptake transmembrane transporter activity	F	Enables the transfer of formate from the outside of a cell to the inside of the cell across a membrane.
15660	formate efflux transmembrane transporter activity	F	Catalysis of the transfer of formate from the inside of the cell to the outside of the cell across a membrane.
15661	L-lysine efflux transmembrane transporter activity	F	Catalysis of the transfer of L-lysine from the inside of the cell to the outside of the cell across a membrane.
15662	ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O = ADP + phosphate, to directly drive the transport of ions across a membrane. The reaction is characterized by the transient formation of a high-energy aspartyl-phosphoryl-enzyme intermediate.
15663	nicotinamide mononucleotide transmembrane transporter activity	F	Enables the directed movement of nicotinamide mononucleotide into, out of or within a cell, or between cells. Nicotinamide mononucleotide is a ribonucleotide in which the nitrogenous base, nicotinamide, is in beta-n-glycosidic linkage with the c-1 position of d-ribose. It is a constituent of NAD and NADP.
15665	alcohol transmembrane transporter activity	F	Enables the transfer of an alcohol from one side of the membrane to the other. An alcohol is any carbon compound that contains a hydroxyl group.
15666	restriction endodeoxyribonuclease activity	F	Catalysis of endonucleolytic cleavage of DNA in a site-specific manner, resulting in double-strand breaks.
15667	site-specific DNA-methyltransferase (cytosine-N4-specific) activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + DNA cytosine = S-adenosyl-L-homocysteine + DNA N4-methylcytosine.
15668	Type III site-specific deoxyribonuclease activity	F	Catalysis of the endonucleolytic cleavage of DNA to give double-stranded fragments with terminal 5'-phosphates. ATP hydrolysis is required. Cleavage is dependent on the presence of two copies of a specific recognition sequence in an inverse orientation in the DNA. Cleavage occurs at a specific distance from one of the recognition sites.
15669	gas transport	P	The directed movement of substances that are gaseous in normal living conditions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
15670	carbon dioxide transport	P	The directed movement of carbon dioxide (CO2) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
15671	oxygen transport	P	The directed movement of oxygen (O2) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
15672	monovalent inorganic cation transport	P	The directed movement of inorganic cations with a valency of one into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Inorganic cations are atoms or small molecules with a positive charge which do not contain carbon in covalent linkage.
15673	silver ion transport	P	The directed movement of silver (Ag) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
15675	nickel cation transport	P	The directed movement of nickel (Ni) cations into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
15676	vanadium ion transport	P	The directed movement of vanadium (V) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
15677	copper ion import	P	The directed movement of copper ions into a cell or organelle.
15678	high-affinity copper ion transport	P	The directed, high-affinity movement of copper (Cu) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.
15679	plasma membrane copper ion transport	P	The directed movement of copper ions across the plasma membrane.
15680	intracellular copper ion transport	P	The directed movement of copper (Cu) ions within a cell.
15682	ferric iron transport	P	The directed movement of ferric iron (Fe(III) or Fe3+) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
15683	high-affinity ferric iron transport	P	The directed, high-affinity movement of ferric (Fe(III) or Fe3+) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.
15684	ferrous iron transport	P	The directed movement of ferrous iron (Fe(II) or Fe2+) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
15685	ferric-enterobactin transport	P	The directed movement of ferric-enterobactin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
15686	ferric triacetylfusarinine C transport	P	The directed movement of ferric triacetylfusarinine C into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
15687	ferric-hydroxamate transport	P	The directed movement of ferric-hydroxamate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
15688	iron chelate transport	P	The directed movement of iron chelates into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. An iron chelate is a heterocyclic compound having a metal ion attached by coordinate bonds to at least two nonmetal ions.
15689	molybdate ion transport	P	The directed movement of molybdate (MoO4 2-) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Molybdate is the bivalent anion derived from molybdic acid.
15690	aluminum cation transport	P	The directed movement of aluminum (Al) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
15691	cadmium ion transport	P	The directed movement of cadmium (Cd) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
15692	lead ion transport	P	The directed movement of lead (Pb) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
15693	magnesium ion transport	P	The directed movement of magnesium (Mg) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
15694	mercury ion transport	P	The directed movement of mercury (Hg) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
15695	organic cation transport	P	The directed movement of organic cations into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Organic cations are atoms or small molecules with a positive charge which contain carbon in covalent linkage.
15696	ammonium transport	P	The directed movement of ammonium into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Ammonium is the cation NH4+ which is formed from N2 by root-nodule bacteria in leguminous plants and is an excretory product in ammonotelic animals.
15697	quaternary ammonium group transport	P	The directed movement into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore of quaternary ammonium compounds, any compound that can be regarded as derived from ammonium hydroxide or an ammonium salt by replacement of all four hydrogen atoms of the NH4+ ion by organic groups.
15698	inorganic anion transport	P	The directed movement of inorganic anions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Inorganic anions are atoms or small molecules with a negative charge which do not contain carbon in covalent linkage.
15699	antimonite transport	P	The directed movement of antimonite into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
15700	arsenite transport	P	The directed movement of arsenite into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
15701	bicarbonate transport	P	The directed movement of bicarbonate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
15702	chlorate transport	P	The directed movement of chlorate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
15703	chromate transport	P	The directed movement of chromate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
15704	cyanate transport	P	The directed movement of cyanate, NCO-, the anion of cyanic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
15705	iodide transport	P	The directed movement of iodide into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
15706	nitrate transport	P	The directed movement of nitrate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
15707	nitrite transport	P	The directed movement of nitrite into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
15708	silicate transport	P	The directed movement of silicates into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Silicates are the salts of silicic acids, and are usually composed of silicon and oxygen (Si[x]O[y]), one or more metals, and possibly hydrogen. Types of silicate include unisilicates, metasilicates and hydrous silicates.
15709	thiosulfate transport	P	The directed movement of thiosulfate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
15710	tellurite transport	P	The directed movement of tellurite into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
15711	organic anion transport	P	The directed movement of organic anions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Organic anions are atoms or small molecules with a negative charge which contain carbon in covalent linkage.
15712	hexose phosphate transport	P	The directed movement of hexose phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
15713	phosphoglycerate transport	P	The directed movement of phosphoglycerate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
15714	phosphoenolpyruvate transport	P	The directed movement of phosphoenolpyruvate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
15715	nucleotide-sulfate transport	P	The directed movement of nucleotide sulfate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
15716	organic phosphonate transport	P	The directed movement of phosphonates into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A phosphonate is any salt, anion, or ester of phosphonic acid (HPO(OH)2).
15717	triose phosphate transport	P	The directed movement of triose phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
15718	monocarboxylic acid transport	P	The directed movement of monocarboxylic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
15719	allantoate transport	P	The directed movement of allantoate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
15720	allantoin transport	P	The directed movement of allantoin, (2,5-dioxo-4-imidazolidinyl)urea, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
15721	bile acid and bile salt transport	P	The directed movement of bile acid and bile salts into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
15722	canalicular bile acid transport	P	Catalysis of the transfer of bile acid from one side of a hepatocyte plasma membrane into a bile canaliculus. Bile canaliculi are the thin tubes formed by hepatocyte membranes. Bile acids are any of a group of steroid carboxylic acids occurring in bile, where they are present as the sodium salts of their amides with glycine or taurine.
15723	bilirubin transport	P	The directed movement of bilirubin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
15724	formate transport	P	The directed movement of formate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
15725	gluconate transport	P	The directed movement of gluconate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Gluconate is the aldonic acid derived from glucose.
15726	L-idonate transport	P	The directed movement of L-idonate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. L-idonate is an aldonic acid derived from L-idose, an aldohexose which is epimeric with D-glucose.
15727	lactate transport	P	The directed movement of lactate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Lactate is 2-hydroxypropanoate, CH3-CHOH-COOH; L(+)-lactate is formed by anaerobic glycolysis in animal tissues, and DL-lactate is found in sour milk, molasses and certain fruit juices.
15728	mevalonate transport	P	The directed movement of mevalonate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
15729	oxaloacetate transport	P	The directed movement of oxaloacetate, the anion of oxobutanedioic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
15730	propanoate transport	P	The directed movement of propionate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
15731	3-hydroxyphenyl propanoate transport	P	The directed movement of 3-hydroxyphenyl propanoate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
15732	prostaglandin transport	P	The directed movement of prostaglandins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
15733	shikimate transport	P	The directed movement of shikimate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
15734	taurine transport	P	The directed movement of taurine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
15735	uronic acid transport	P	The directed movement of uronic acid into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
15736	hexuronate transport	P	The directed movement of hexuronate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A hexuronate is any monocarboxylic acid derived from a hexose by oxidation of C-6.
15737	galacturonate transport	P	The directed movement of galacturonate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
15738	glucuronate transport	P	The directed movement of glucuronate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
15739	sialic acid transport	P	The directed movement of sialic acid into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
15740	C4-dicarboxylate transport	P	The directed movement of a C4-dicarboxylate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A C4-dicarboxylate is the anion of a dicarboxylic acid that contains four carbon atoms.
15741	fumarate transport	P	The directed movement of fumarate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
15742	alpha-ketoglutarate transport	P	The directed movement of alpha-ketoglutarate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
15743	malate transport	P	The directed movement of malate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
15744	succinate transport	P	The directed movement of succinate, the dianion of ethane dicarboxylic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
15745	tartrate transport	P	The directed movement of tartrate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
15746	citrate transport	P	The directed movement of citrate, 2-hydroxy-1,2,3-propanetricarboyxlate, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
15747	urate transport	P	The directed movement of urate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
15748	organophosphate ester transport	P	The directed movement of organophosphate esters into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Organophosphate esters are small organic molecules containing phosphate ester bonds.
15749	monosaccharide transport	P	The directed movement of monosaccharides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Monosaccharides are the simplest carbohydrates; they are polyhydric alcohols containing either an aldehyde or a keto group and between three to ten or more carbon atoms. They form the constitutional repeating units of oligo- and polysaccharides.
15750	pentose transport	P	The directed movement of pentoses into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A pentose is any aldose with a chain of five carbon atoms in the molecule.
15751	arabinose transport	P	The directed movement of arabinose, a pentose monosaccharide that occurs in both D and L configurations, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
15752	D-ribose transport	P	The directed movement of D-ribose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. As beta-D-ribofuranose, D-ribose forms the glycose group of all ribonucleosides, ribonucleotides and ribonucleic acids, and also of ribose phosphates, various glycosides, some coenzymes and some forms of vitamin B12.
15753	D-xylose transport	P	The directed movement of D-xylose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. D-xylose (the naturally occurring enantiomer is always D-) is a constituent of plant polysaccharides.
15754	allose transport	P	The directed movement of allose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Allose is an aldohexose similar to glucose, differing only in the configuration of the hydroxyl group of C-3.
15755	fructose transport	P	The directed movement of fructose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Fructose exists in a open chain form or as a ring compound. D-fructose is the sweetest of the sugars and is found free in a large number of fruits and honey.
15756	fucose transport	P	The directed movement of fucose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Fucose is 6-deoxygalactose and has two enantiomers, D-fucose and L-fucose.
15757	galactose transport	P	The directed movement of galactose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. D-galactose is widely distributed in combined form in plants, animals and microorganisms as a constituent of oligo- and polysaccharides; it also occurs in galactolipids and as its glucoside in lactose and melibiose.
15758	glucose transport	P	The directed movement of the hexose monosaccharide glucose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
15759	beta-glucoside transport	P	The directed movement of beta-glucosides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Beta-glucosides are glycosides in which the sugar group is a glucose residue, and the anomeric carbon of the bond is in a beta configuration.
15760	glucose-6-phosphate transport	P	The directed movement of glucose-6-phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Glucose-6-phosphate is a monophosphorylated derivative of glucose with the phosphate group attached to C-6.
15761	mannose transport	P	The directed movement of mannose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Mannose is the aldohexose manno-hexose, the C-2 epimer of glucose. The D-(+)-form is widely distributed in mannans and hemicelluloses and is of major importance in the core oligosaccharide of N-linked oligosaccharides of glycoproteins.
15762	rhamnose transport	P	The directed movement of rhamnose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Rhamnose occurs commonly as a compound of plant glycosides, in polysaccharides of gums and mucilages, and in bacterial polysaccharides. It is also a component of some plant cell wall polysaccharides and frequently acts as the sugar components of flavonoids.
15763	N-acetylgalactosamine transport	P	The directed movement of N-acetylgalactosamine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. N-acetylgalactosamine, 2-acetamido-2-deoxygalactopyranose, is the n-acetyl derivative of galactosamine.
15764	N-acetylglucosamine transport	P	The directed movement of N-acetylglucosamine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
15765	methylgalactoside transport	P	The directed movement of methylgalactoside into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Methylgalactoside is a compound in which the H of the OH group on carbon-1 of galactose is replaced by a methyl group.
15766	disaccharide transport	P	The directed movement of disaccharides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Disaccharides are sugars composed of two monosaccharide units.
15767	lactose transport	P	The directed movement of lactose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Lactose is a disaccharide 4-O-beta-D-galactopyranosyl-D-glucose, and constitutes roughly 5% of the milk in almost all mammals.
15768	maltose transport	P	The directed movement of maltose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Maltose is the disaccharide 4-O-alpha-D-glucopyranosyl-D-glucopyranose, an intermediate in the catabolism of glycogen and starch.
15769	melibiose transport	P	The directed movement of melibiose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Melibiose is the disaccharide 6-O-alpha-D-galactopyranosyl-D-glucose.
15770	sucrose transport	P	The directed movement of sucrose into, out of or within a cell, or between cells by means of some agent such as a transporter or pore. Sucrose is the disaccharide fructofuranosyl-glucopyranoside.
15771	trehalose transport	P	The directed movement of trehalose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Trehalose is a disaccharide isomeric with sucrose and obtained from certain lichens and fungi.
15772	oligosaccharide transport	P	The directed movement of oligosaccharides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Oligosaccharides are molecules with between two and (about) 20 monosaccharide residues connected by glycosidic linkages.
15773	raffinose transport	P	The directed movement of raffinose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Raffinose occurs in plants almost as commonly as sucrose and is present in cereal grains, cotton seeds, and many legumes. It is synthesized from sucrose by transfer of a galactopyranoside from myo-inositol.
15774	polysaccharide transport	P	The directed movement of polysaccharides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A polysaccharide is a polymer of many (typically more than 10) monosaccharide residues linked glycosidically.
15775	beta-glucan transport	P	The directed movement of beta-glucans into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Beta-glucans are compounds composed of glucose residues linked by beta-glucosidic bonds.
15776	capsular polysaccharide transport	P	The directed movement of capsular polysaccharides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Capsular polysaccharides make up the capsule, a protective structure surrounding some species of bacteria and fungi.
15777	teichoic acid transport	P	The directed movement of teichoic acid into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Teichoic acid is any polymer occurring in the cell wall, membrane or capsule of Gram-positive bacteria and containing chains of glycerol phosphate or ribitol phosphate residues.
15778	hexuronide transport	P	The directed movement of hexuronide into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Hexuronides are any compound formed by combination of glycosidic linkage of a hydroxy compound (e.g. an alcohol or a saccharide) with the anomeric carbon atom of a hexuronate.
15779	glucuronoside transport	P	The directed movement of glucuronosides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Glucuronosides are any compound formed by combination of glycosidic linkage of a hydroxy compound (e.g. an alcohol or a saccharide) with the anomeric carbon atom of glucuronate.
15780	nucleotide-sugar transport	P	The directed movement of nucleotide-sugars into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Nucleotide-sugars are any nucleotide in which the distal phosphoric residue of a nucleoside 5'-diphosphate is in glycosidic linkage with a monosaccharide or monosaccharide derivative.
15781	pyrimidine nucleotide-sugar transport	P	The directed movement of pyrimidine nucleotide-sugars into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Pyrimidine nucleotide-sugars are pyrimidine nucleotides in glycosidic linkage with a monosaccharide or monosaccharide derivative.
15782	CMP-N-acetylneuraminate transport	P	The directed movement of CMP-N-acetylneuraminate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
15783	GDP-fucose transport	P	The directed movement of GDP-fucose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GDP-fucose is a substance composed of fucose in glycosidic linkage with guanosine diphosphate.
15784	GDP-mannose transport	P	The directed movement of GDP-mannose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. GDP-mannose is a substance composed of mannose in glycosidic linkage with guanosine diphosphate.
15785	UDP-galactose transport	P	The directed movement of UDP-galactose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. UDP-galactose is a substance composed of galactose in glycosidic linkage with uridine diphosphate.
15786	UDP-glucose transport	P	The directed movement of UDP-glucose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. UDP-glucose is a substance composed of glucose in glycosidic linkage with uridine diphosphate.
15787	UDP-glucuronic acid transport	P	The directed movement of UDP-glucuronic acid into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. UDP-glucuronic acid is a substance composed of glucuronic acid in glycosidic linkage with uridine diphosphate.
15788	UDP-N-acetylglucosamine transport	P	The directed movement of UDP-N-acetylglucosamine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. N-acetylglucosamine is a substance composed of N-acetylglucosamine, a common structural unit of oligosaccharides, in glycosidic linkage with uridine diphosphate.
15789	UDP-N-acetylgalactosamine transport	P	The directed movement of UDP-N-acetylgalactosamine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. UDP-N-acetylgalactosamine is a substance composed of N-acetylgalactosamine, a common structural unit of oligosaccharides, in glycosidic linkage with uridine diphosphate.
15790	UDP-xylose transport	P	The directed movement of UDP-xylose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. UDP-xylose is a substance composed of xylose in glycosidic linkage with uridine diphosphate.
15791	polyol transport	P	The directed movement of polyols, any polyhydric alcohol, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
15792	arabinitol transport	P	The directed movement of arabitol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Arabitol is the pentitol derived from arabinose or lyxose by reduction of the aldehyde group. The D enantiomer is present in lichens and mushrooms.
15793	glycerol transport	P	The directed movement of glycerol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Glycerol is 1,2,3-propanetriol, a sweet, hygroscopic, viscous liquid, widely distributed in nature as a constituent of many lipids.
15794	glycerol-3-phosphate transport	P	The directed movement of glycerol-3-phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Glycerol-3-phosphate is a phosphoric monoester of glycerol.
15795	sorbitol transport	P	The directed movement of sorbitol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Sorbitol, also known as glucitol, is the hexitol derived by the reduction of the aldehyde group of glucose.
15796	galactitol transport	P	The directed movement of galactitol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Galactitol is the hexitol derived by the reduction of the aldehyde group of either D- or L-galactose.
15797	mannitol transport	P	The directed movement of mannitol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Mannitol is the alditol derived from D-mannose by reduction of the aldehyde group.
15798	myo-inositol transport	P	The directed movement of myo-inositol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Myo-inositol is 1,2,3,4,5/4,6-cyclohexanehexol, a growth factor for animals and microorganisms.
15799	propanediol transport	P	The directed movement of propanediol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Propanediol is a sweet colorless, viscous, hygroscopic liquid used as an antifreeze and in brake fluid; it is also as a humectant in cosmetics and personal care items, although it can be absorbed through the skin with harmful effects.
15800	acidic amino acid transport	P	The directed movement of acidic amino acids, amino acids with a pH below 7, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
15801	aromatic amino acid transport	P	The directed movement of aromatic amino acids, amino acids with aromatic ring, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
15802	basic amino acid transport	P	The directed movement of basic amino acids, amino acids with a pH above 7, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
15803	branched-chain amino acid transport	P	The directed movement of branched-chain amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Branched-chain amino acids are amino acids with a branched carbon skeleton without rings.
15804	neutral amino acid transport	P	The directed movement of neutral amino acids, amino acids with no net charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
15805	S-adenosyl-L-methionine transport	P	The directed movement of S-adenosylmethionine, S-(5'-adenosyl)-L-methionine, an important intermediate in one-carbon metabolism, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
15806	S-methylmethionine transport	P	The directed movement of S-methylmethionine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
15807	L-amino acid transport	P	The directed movement of L-enantiomer amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
15808	L-alanine transport	P	The directed movement of L-alanine, the L-enantiomer of 2-aminopropanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
15809	arginine transport	P	The directed movement of arginine, 2-amino-5-guanidinopentanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
15810	aspartate transport	P	The directed movement of aspartate, the anion of aspartic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
15811	L-cystine transport	P	The directed movement of L-cystine (also known as dicysteine) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
15812	gamma-aminobutyric acid transport	P	The directed movement of gamma-aminobutyric acid (GABA, 4-aminobutyrate), an amino acid which acts as a neurotransmitter in some organisms, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
15813	L-glutamate transport	P	The directed movement of L-glutamate, the L enantiomer anion of 2-aminopentanedioic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
15814	p-aminobenzoyl-glutamate transport	P	The directed movement of p-aminobenzoyl-glutamate, the anion of p-aminobenzoyl-glutamic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
15816	glycine transport	P	The directed movement of glycine, aminoethanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
15817	histidine transport	P	The directed movement of histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
15818	isoleucine transport	P	The directed movement of isoleucine, (2R*,3R*)-2-amino-3-methylpentanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
15819	lysine transport	P	The directed movement of lysine, 2,6-diaminohexanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
15820	leucine transport	P	The directed movement of leucine, 2-amino-4-methylpentanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
15821	methionine transport	P	The directed movement of methionine, 2-amino-4-(methylthio)butanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
15822	ornithine transport	P	The directed movement of ornithine, 2,5-diaminopentanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
15823	phenylalanine transport	P	The directed movement of phenylalanine, 2-amino-3-phenylpropanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
15824	proline transport	P	The directed movement of proline, pyrrolidine-2-carboxylic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
15825	L-serine transport	P	The directed movement of L-serine, the L-enantiomer of 2-amino-3-hydroxypropanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
15826	threonine transport	P	The directed movement of threonine, (2R*,3S*)-2-amino-3-hydroxybutanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
15827	tryptophan transport	P	The directed movement of tryptophan, 2-amino-3-(1H-indol-3-yl)propanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
15828	tyrosine transport	P	The directed movement of tyrosine, 2-amino-3-(4-hydroxyphenyl)propanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
15829	valine transport	P	The directed movement of valine, 2-amino-3-methylbutanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
15830	diaminopimelate transport	P	The directed movement of diaminopimelate, the anion of 2,6-diaminoheptanedioic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
15833	peptide transport	P	The directed movement of peptides, compounds of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
15834	peptidoglycan-associated peptide transport	P	The directed movement of peptidoglycan peptides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Peptidoglycan peptides are the oligopeptides found in peptidoglycan networks which cross-link the polysaccharide chains.
15835	peptidoglycan transport	P	The directed movement of peptidoglycans, a class of glycoconjugates found in bacterial cell walls, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
15836	lipid-linked peptidoglycan transport	P	The directed movement of lipid-linked peptidoglycans into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
15837	amine transport	P	The directed movement of amines, including polyamines, organic compounds containing one or more amino groups, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
15838	amino-acid betaine transport	P	The directed movement of betaine, the N-trimethyl derivative of an amino acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
15839	cadaverine transport	P	The directed movement of cadaverine, 1,5-pentanediamine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
15840	urea transport	P	The directed movement of urea into, out of or within the cell. Urea is the water-soluble compound H2N-CO-NH2.
15841	chromaffin granule amine transport	P	The directed movement of amines into, out of or within chromaffin granules.
15842	aminergic neurotransmitter loading into synaptic vesicle	P	The active transport of aminergic neurotransmitters into a synaptic vesicle. This import is fuelled by an electrochemical gradient across the vesicle membrane, established by the action proton pumps.
15843	methylammonium transport	P	The directed movement of methylammonium into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
15844	monoamine transport	P	The directed movement of monoamines, organic compounds that contain one amino group that is connected to an aromatic ring by an ethylene group (-CH2-CH2-), into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
15846	polyamine transport	P	The directed movement of polyamines, organic compounds containing two or more amino groups, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
15847	putrescine transport	P	The directed movement of putrescine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Putrescine is 1,4-diaminobutane, the polyamine formed by decarboxylation of ornithine and the metabolic precursor of spermidine and spermine.
15848	spermidine transport	P	The directed movement of spermidine, N-(3-aminopropyl)-1,4-diaminobutane, a polyamine formed by the transfer of a propylamine group from decarboxylated S-adenosylmethionine to putrescine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
15849	organic acid transport	P	The directed movement of organic acids, any acidic compound containing carbon in covalent linkage, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
15850	organic hydroxy compound transport	P	The directed movement of an organic hydroxy compound (organic alcohol) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. An organic hydroxy compound is an organic compound having at least one hydroxy group attached to a carbon atom.
15851	nucleobase transport	P	The directed movement of a nucleobase, any nitrogenous base that is a constituent of a nucleoside, nucleotide, or nucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
15853	adenine transport	P	The directed movement of adenine, 6-aminopurine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
15854	guanine transport	P	The directed movement of guanine, 2-amino-6-hydroxypurine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
15855	pyrimidine nucleobase transport	P	The directed movement of pyrimidine nucleobases, one of the two classes of nitrogen-containing ring compounds found in DNA and RNA, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
15856	cytosine transport	P	The directed movement of cytosine, 4-amino-2-hydroxypyrimidine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
15857	uracil transport	P	The directed movement of uracil, 2,4-dioxopyrimidine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
15858	nucleoside transport	P	The directed movement of a nucleoside, a nucleobase linked to either beta-D-ribofuranose (ribonucleoside) or 2-deoxy-beta-D-ribofuranose, (a deoxyribonucleotide), into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
15859	intracellular nucleoside transport	P	The directed movement of a nucleoside, a nucleobase linked to either beta-D-ribofuranose (ribonucleoside) or 2-deoxy-beta-D-ribofuranose, (a deoxyribonucleotide), within a cell.
15860	purine nucleoside transmembrane transport	P	The directed movement of a purine nucleoside across a membrane. A purine nucleoside is a purine base covalently bonded to a ribose or deoxyribose sugar.
15861	cytidine transport	P	The directed movement of cytidine, cytosine riboside, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
15862	uridine transport	P	The directed movement of uridine, uracil riboside, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
15863	xanthosine transport	P	The directed movement of xanthosine, xanthine riboside, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
15864	pyrimidine nucleoside transport	P	The directed movement of a pyrimidine nucleoside, a pyrimidine base covalently bonded to a ribose or deoxyribose sugar, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
15865	purine nucleotide transport	P	The directed movement of a purine nucleotide, any compound consisting of a purine nucleoside esterified with (ortho)phosphate, into, out of or within a cell.
15866	ADP transport	P	The directed movement of ADP, adenosine diphosphate, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
15867	ATP transport	P	The directed movement of ATP, adenosine triphosphate, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
15868	purine ribonucleotide transport	P	The directed movement of a purine ribonucleotide, any compound consisting of a purine ribonucleoside (a purine organic base attached to a ribose sugar) esterified with (ortho)phosphate, into, out of or within a cell.
15869	protein-DNA complex transport	P	The directed movement of protein-DNA complexes into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
15870	acetylcholine transport	P	The directed movement of acetylcholine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Acetylcholine is an acetic acid ester of the organic base choline and functions as a neurotransmitter, released at the synapses of parasympathetic nerves and at neuromuscular junctions.
15871	choline transport	P	The directed movement of choline into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Choline (2-hydroxyethyltrimethylammonium) is an amino alcohol that occurs widely in living organisms as a constituent of certain types of phospholipids and in the neurotransmitter acetylcholine.
15872	dopamine transport	P	The directed movement of dopamine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Dopamine is a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline.
15874	norepinephrine transport	P	The directed movement of norepinephrine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Norepinephrine (3,4-dihydroxyphenyl-2-aminoethanol) is a hormone secreted by the adrenal medulla and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts of the CNS. It is also the biosynthetic precursor of epinephrine.
15876	acetyl-CoA transport	P	The directed movement of acetyl-CoA into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Acetyl-CoA is a derivative of coenzyme A in which the sulfhydryl group is acetylated; it is a metabolite derived from several pathways (e.g. glycolysis, fatty acid oxidation, amino-acid catabolism) and is further metabolized by the tricarboxylic acid cycle. It is a key intermediate in lipid and terpenoid biosynthesis.
15877	biopterin transport	P	The directed movement of biopterin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Biopterin is a growth factor for certain protozoans and some insects; it is widely distributed in tissues and functions in a reduced form, tetrahydrobiopterin, as a hydroxylation coenzyme.
15878	biotin transport	P	The directed movement of biotin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Biotin is cis-tetrahydro-2-oxothieno(3,4-d)imidazoline-4-valeric acid; the (+) enantiomer is very widely distributed in cells and serves as a carrier in a number of enzymatic beta-carboxylation reactions.
15879	carnitine transport	P	The directed movement of carnitine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Carnitine is a compound that participates in the transfer of acyl groups across the inner mitochondrial membrane.
15880	coenzyme A transport	P	The directed movement of coenzyme A into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Coenzyme A, 3'-phosphoadenosine-(5')diphospho(4')pantatheine, is an acyl carrier in many acylation and acyl-transfer reactions in which the intermediate is a thiol ester.
15881	creatine transport	P	The directed movement of creatine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Creatine is a compound synthesized from the amino acids arginine, glycine, and methionine that occurs in muscle.
15882	L-ascorbic acid transport	P	The directed movement of L-ascorbic acid into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. L-ascorbate, (2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2,5-dihydrofuran-3-olate, is vitamin C and has co-factor and anti-oxidant activities in many species.
15883	FAD transport	P	The directed movement of flavin-adenine dinucleotide (FAD) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. FAD forms the coenzyme of the prosthetic group of various flavoprotein oxidoreductase enzymes, in which it functions as an electron acceptor by being reversibly converted to its reduced form.
15884	folic acid transport	P	The directed movement of folic acid (pteroylglutamic acid) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Folic acid is widely distributed as a member of the vitamin B complex and is essential for the synthesis of purine and pyrimidines.
15885	5-formyltetrahydrofolate transport	P	The directed movement of 5-formyltetrahydrofolate, the formylated derivative of tetrahydrofolate, into, out of, within, or between cells, by means of some agent such as a transporter or pore.
15886	heme transport	P	The directed movement of heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
15887	pantothenate transmembrane transport	P	The directed movement of pantothenate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Pantothenate is the anion of pantothenic acid, the amide of beta-alanine and pantoic acid; it is a B complex vitamin that is a constituent of coenzyme A and is distributed ubiquitously in foods.
15888	thiamine transport	P	The directed movement of thiamine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Thiamine is vitamin B1, a water soluble vitamin present in fresh vegetables and meats, especially liver.
15889	cobalamin transport	P	The directed movement of cobalamin (vitamin B12), a water-soluble vitamin characterized by possession of a corrin nucleus containing a cobalt atom, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
15890	nicotinamide mononucleotide transport	P	The directed movement of nicotinamide mononucleotide into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Nicotinamide mononucleotide is a ribonucleotide in which the nitrogenous base, nicotinamide, is in beta-n-glycosidic linkage with the c-1 position of D-ribose. It is a constituent of NAD and NADP.
15891	siderophore transport	P	The directed movement of siderophores, low molecular weight Fe(III)-chelating substances, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
15893	drug transport	P	The directed movement of a drug, a substance used in the diagnosis, treatment or prevention of a disease, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
15894	acriflavine transport	P	The directed movement of acriflavine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Acriflavine is a fluorescent dye used as a local antiseptic and also as a biological stain. It intercalates into nucleic acids thereby inhibiting bacterial and viral replication.
15895	alkane transport	P	The directed movement of alkanes into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Alkanes are saturated aliphatic hydrocarbon compounds.
15896	nalidixic acid transport	P	The directed movement of nalidixic acid into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Nalidixic acid is a synthetic antibiotic that interferes with DNA gyrase and inhibits prokaryotic replication.
15897	organomercurial transport	P	The directed movement of organomercurial compounds into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Organomercurial substances are any organic compound containing a mercury atom.
15898	amiloride transport	P	The directed movement amiloride into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Amiloride is a potent and specific inhibitor of sodium ion entry into cells. It is used as a potassium-sparing diuretic.
15899	aminotriazole transport	P	The directed movement of aminotriazole into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Aminotriazole is an effective weed killer that also possesses some antithyroid activity.
15900	benomyl transport	P	The directed movement of benomyl into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Benomyl, methyl 1-(butylcarbamoyl)-2-benzimidazolecarbamate, is a systemic agricultural fungicide used for control of certain fungal diseases of stone fruit.
15901	cycloheximide transport	P	The directed movement of cycloheximide into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Cycloheximide is an antibiotic produced by Streptomyces which interferes with protein synthesis in eukaryotes.
15902	carbonyl cyanide m-chlorophenylhydrazone transport	P	The directed movement of carbonyl cyanide m-chlorophenylhydrazone into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Carbonyl cyanide m-chlorophenylhydrazone is a proton ionophore, commonly used as an uncoupling agent and inhibitor of photosynthesis because of its effects on mitochondrial and chloroplast membranes.
15903	fluconazole transport	P	The directed movement of fluconazole into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Fluconazole is an antifungal drug used for oral candidiasis and cryptococcal meningitis; it is still under study for treatment of vaginal candidiasis and other fungal infections.
15904	tetracycline transport	P	The directed movement of tetracycline into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Tetracycline is a broad spectrum antibiotic that blocks binding of aminoacyl tRNA to the ribosomes of both Gram-positive and Gram-negative organisms (and those of organelles).
15905	bicyclomycin transport	P	The directed movement of bicyclomycin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Bicyclomycin (or bicozamycin) is an antibacterial drug often used as a livestock feed additive.
15906	sulfathiazole transport	P	The directed movement of sulfathiazole into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Sulfathiazole is an antibacterial agent of the sulfonamide group.
15908	fatty acid transport	P	The directed movement of fatty acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Fatty acids are aliphatic monocarboxylic acids liberated from naturally occurring fats and oils by hydrolysis.
15909	long-chain fatty acid transport	P	The directed movement of long-chain fatty acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A long-chain fatty acid is a fatty acid with a chain length between C13 and C22.
15910	peroxisomal long-chain fatty acid import	P	The directed movement of long-chain fatty acids into a peroxisome. A long-chain fatty acid is a fatty acid with a chain length between C13 and C22.
15911	plasma membrane long-chain fatty acid transport	P	The directed movement of long-chain fatty acids across the plasma membrane. A long-chain fatty acid is a fatty acid with a chain length between C13 and C22.
15912	short-chain fatty acid transport	P	The directed movement of short-chain fatty acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Short-chain fatty acids are fatty acids with a chain length of less than C6.
15913	short-chain fatty acid import	P	The directed movement of short-chain fatty acids into a cell or organelle. Short-chain fatty acids are fatty acids with a chain length of less than C6.
15914	phospholipid transport	P	The directed movement of phospholipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Phospholipids are any lipids containing phosphoric acid as a mono- or diester.
15915	fatty-acyl group transport	P	The directed movement of fatty acyl groups into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A fatty acyl group is any acyl group derived from a fatty acid.
15916	fatty-acyl-CoA transport	P	The directed movement of fatty acyl coenzyme A into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Fatty acyl coenzyme A is an acyl group linked to 3'-phosphoadenosine-(5')diphospho(4')pantatheine (coenzyme A).
15917	aminophospholipid transport	P	The directed movement of aminophospholipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Aminophospholipids contain phosphoric acid as a mono- or diester and an amino (NH2) group.
15918	sterol transport	P	The directed movement of sterols into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Sterols are steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule.
15919	peroxisomal membrane transport	P	The directed movement of substances to, from or across the peroxisomal membrane.
15920	lipopolysaccharide transport	P	The directed movement of lipopolysaccharides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A lipopolysaccharide is any of a group of related, structurally complex components of the outer membrane of Gram-negative bacteria. Lipopolysaccharides consist three covalently linked regions, lipid A, core oligosaccharide, and an O side chain. Lipid A is responsible for the toxicity of the lipopolysaccharide.
15921	lipopolysaccharide export	P	The directed movement of lipopolysaccharides out of a cell or organelle.
15922	aspartate oxidase activity	F	Catalysis of the reaction: aspartate + O2 = iminosuccinate + hydrogen peroxide.
15923	mannosidase activity	F	Catalysis of the hydrolysis of mannosyl compounds, substances containing a group derived from a cyclic form of mannose or a mannose derivative.
15924	mannosyl-oligosaccharide mannosidase activity	F	Catalysis of the hydrolysis of the terminal alpha-D-mannose residues in oligo-mannose oligosaccharides.
15925	galactosidase activity	F	Catalysis of the hydrolysis of galactosyl compounds, substances containing a group derived from a cyclic form of galactose or a galactose derivative.
15926	glucosidase activity	F	Catalysis of the hydrolysis of glucosyl compounds, substances containing a group derived from a cyclic form of glucose or a glucose derivative.
15927	trehalase activity	F	Catalysis of the hydrolysis of trehalose or a trehalose derivative.
15928	fucosidase activity	F	Catalysis of the hydrolysis of fucosyl compounds, substances containing a group derived from a cyclic form of fucose or a fucose derivative.
15929	hexosaminidase activity	F	Catalysis of the cleavage of hexosamine or N-acetylhexosamine residues (e.g. N-acetylglucosamine) residues from gangliosides or other glycoside oligosaccharides.
15930	glutamate synthase activity	F	Catalysis of the formation of L-glutamine and 2-oxoglutarate from L-glutamate, using NADH, NADPH or ferredoxin as hydrogen acceptors.
15931	nucleobase-containing compound transport	P	The directed movement of nucleobases, nucleosides, nucleotides and nucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
15932	nucleobase-containing compound transmembrane transporter activity	F	Enables the transfer of nucleobases, nucleosides, nucleotides and nucleic acids from one side of a membrane to the other.
15934	large ribosomal subunit	C	The larger of the two subunits of a ribosome. Two sites on the ribosomal large subunit are involved in translation, namely the aminoacyl site (A site) and peptidyl site (P site).
15935	small ribosomal subunit	C	The smaller of the two subunits of a ribosome.
15936	coenzyme A metabolic process	P	The chemical reactions and pathways involving coenzyme A, 3'-phosphoadenosine-(5')diphospho(4')pantatheine, an acyl carrier in many acylation and acyl-transfer reactions in which the intermediate is a thiol ester.
15937	coenzyme A biosynthetic process	P	The chemical reactions and pathways resulting in the formation of coenzyme A, 3'-phosphoadenosine-(5')diphospho(4')pantatheine, an acyl carrier in many acylation and acyl-transfer reactions in which the intermediate is a thiol ester.
15938	coenzyme A catabolic process	P	The chemical reactions and pathways resulting in the breakdown of coenzyme A, 3'-phosphoadenosine-(5')diphospho(4')pantatheine, an acyl carrier in many acylation and acyl-transfer reactions in which the intermediate is a thiol ester.
15939	pantothenate metabolic process	P	The chemical reactions and pathways involving pantothenate, the anion of pantothenic acid, the amide of beta-alanine and pantoic acid. It is a B complex vitamin that is a constituent of coenzyme A and is distributed ubiquitously in foods.
15940	pantothenate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of pantothenate, the anion of pantothenic acid. It is a B complex vitamin that is a constituent of coenzyme A and is distributed ubiquitously in foods.
15941	pantothenate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of pantothenate, the anion of pantothenic acid. It is a B complex vitamin that is a constituent of coenzyme A and is distributed ubiquitously in foods.
15942	formate metabolic process	P	The chemical reactions and pathways involving formate, also known as methanoate, the anion HCOO- derived from methanoic (formic) acid.
15943	formate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of formate, also known as methanoate, the anion HCOO- derived from methanoic (formic) acid.
15944	formate oxidation	P	The chemical reactions and pathways by which formate is converted to CO2.
15945	methanol metabolic process	P	The chemical reactions and pathways involving methanol, CH3-OH, a colorless, flammable, mobile, poisonous liquid, widely used as a solvent.
15946	methanol oxidation	P	The chemical reactions and pathways resulting in the conversion of methanol to methyl-Coenzyme M.
15947	methane metabolic process	P	The chemical reactions and pathways involving methane, a colorless, odorless, flammable gas with the formula CH4. It is the simplest of the alkanes.
15948	methanogenesis	P	The chemical reactions and pathways resulting in the formation of methane, a colorless, odorless, flammable gas with the formula CH4. It is the simplest of the alkanes.
15949	nucleobase-containing small molecule interconversion	P	The chemical reactions and pathways by which a nucleobase, nucleoside or nucleotide small molecule is synthesized from another nucleobase, nucleoside or nucleotide small molecule.
15950	purine nucleotide interconversion	P	The chemical reactions and pathways by which a purine nucleotide is synthesized from another purine nucleotide.
15951	purine ribonucleotide interconversion	P	The chemical reactions and pathways by which a purine ribonucleotide is synthesized from another purine ribonucleotide.
15952	purine deoxyribonucleotide interconversion	P	The chemical reactions and pathways by which a purine deoxyribonucleotide is synthesized from another purine deoxyribonucleotide.
15953	pyrimidine nucleotide interconversion	P	The chemical reactions and pathways by which a pyrimidine nucleotide is synthesized from another pyrimidine nucleotide.
15954	pyrimidine ribonucleotide interconversion	P	The chemical reactions and pathways by which a pyrimidine ribonucleotide is synthesized from another pyrimidine ribonucleotide.
15955	pyrimidine deoxyribonucleotide interconversion	P	The chemical reactions and pathways by which a pyrimidine deoxyribonucleotide is synthesized from another pyrimidine deoxyribonucleotide.
15956	bis(5'-nucleosidyl) oligophosphate metabolic process	P	The chemical reactions and pathways involving a bis(5'-nucleosidyl) oligophosphate, a compound formed of two nucleosides joined together through their 5' carbons by a chain of phosphate molecules.
15957	bis(5'-nucleosidyl) oligophosphate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of a bis(5'-nucleosidyl) oligophosphate, a compound formed of two nucleosides joined together through their 5' carbons by a chain of phosphate molecules.
15958	bis(5'-nucleosidyl) oligophosphate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of a bis(5'-nucleosidyl) oligophosphate, a compound formed of two nucleosides joined together through their 5' carbons by a chain of phosphate molecules.
15959	diadenosine polyphosphate metabolic process	P	The chemical reactions and pathways involving diadenosine polyphosphate, a derivative of the nucleoside adenosine with phosphate groups attached.
15960	diadenosine polyphosphate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of diadenosine polyphosphate, a derivative of the nucleoside adenosine with phosphate groups attached.
15961	diadenosine polyphosphate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of diadenosine polyphosphate, a derivative of the nucleoside adenosine with phosphate groups attached.
15962	diadenosine triphosphate metabolic process	P	The chemical reactions and pathways involving diadenosine triphosphate, a derivative of the nucleoside adenosine with three phosphate groups attached.
15963	diadenosine triphosphate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of diadenosine triphosphate, a derivative of the nucleoside adenosine with three phosphate groups attached.
15964	diadenosine triphosphate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of diadenosine triphosphate, a derivative of the nucleoside adenosine with three phosphate groups attached.
15965	diadenosine tetraphosphate metabolic process	P	The chemical reactions and pathways involving diadenosine tetraphosphate, a derivative of the nucleoside adenosine with four phosphate groups attached.
15966	diadenosine tetraphosphate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of diadenosine tetraphosphate, a derivative of the nucleoside adenosine with four phosphate groups attached.
15967	diadenosine tetraphosphate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of diadenosine tetraphosphate, a derivative of the nucleoside adenosine with four phosphate groups attached.
15968	stringent response	P	A specific global change in the metabolism of a bacterial cell (the downregulation of nucleic acid and protein synthesis, and the simultaneous upregulation of protein degradation and amino acid synthesis) as a result of starvation.
15969	guanosine tetraphosphate metabolic process	P	The chemical reactions and pathways involving guanine tetraphosphate (5'-ppGpp-3'), a derivative of guanine riboside with four phosphates.
15970	guanosine tetraphosphate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of guanine tetraphosphate (5'-ppGpp-3'), a derivative of guanine riboside with four phosphates.
15971	guanosine tetraphosphate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of guanine tetraphosphate (5'-ppGpp-3'), a derivative of guanine riboside with four phosphates.
15972	guanosine pentaphosphate metabolic process	P	The chemical reactions and pathways involving guanine pentaphosphate (5'-pppGpp-3'), a derivative of guanine riboside with five phosphates.
15973	guanosine pentaphosphate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of guanine pentaphosphate (5'-pppGpp-3'), a derivative of guanine riboside with five phosphates.
15974	guanosine pentaphosphate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of guanine pentaphosphate (5'-pppGpp-3'), a derivative of guanine riboside with five phosphates.
15975	energy derivation by oxidation of reduced inorganic compounds	P	The chemical reactions and pathways by which a cell derives energy from inorganic compounds; results in the oxidation of the compounds from which energy is released.
15976	carbon utilization	P	A series of processes that forms an integrated mechanism by which a cell or an organism detects the depletion of primary carbon sources and then activates genes to scavenge the last traces of the primary carbon source and to transport and metabolize alternative carbon sources such as carbon dioxide or carbonic acid. The utilization process begins when the cell or organism detects carbon levels, includes the activation of genes whose products detect, transport or metabolize carbon-containing substances, and ends when carbon is incorporated into the cell or organism's metabolism.
15977	carbon fixation	P	A metabolic process in which carbon (usually derived from carbon dioxide) is incorporated into organic compounds (usually carbohydrates).
15979	photosynthesis	P	The synthesis by organisms of organic chemical compounds, especially carbohydrates, from carbon dioxide (CO2) using energy obtained from light rather than from the oxidation of chemical compounds.
15980	energy derivation by oxidation of organic compounds	P	The chemical reactions and pathways by which a cell derives energy from organic compounds; results in the oxidation of the compounds from which energy is released.
15985	energy coupled proton transport, down electrochemical gradient	P	The transport of protons across a membrane to generate an electrochemical gradient (proton-motive force) that provides energy for the synthesis of ATP or GTP.
15986	ATP synthesis coupled proton transport	P	The transport of protons across a membrane to generate an electrochemical gradient (proton-motive force) that powers ATP synthesis.
15987	GTP synthesis coupled proton transport	P	The transport of protons across a membrane to generate an electrochemical gradient (proton-motive force) that powers GTP synthesis.
15988	energy coupled proton transmembrane transport, against electrochemical gradient	P	The transport of protons across a membrane and against an electrochemical gradient, using energy from a source such as ATP hydrolysis, light, or electron transport.
15989	light-driven proton transport	P	The transport of protons against an electrochemical gradient, using energy from light.
15990	electron transport coupled proton transport	P	The transport of protons against an electrochemical gradient, using energy from electron transport.
15991	ATP hydrolysis coupled proton transport	P	The transport of protons against an electrochemical gradient, using energy from ATP hydrolysis.
15992	proton transport	P	The directed movement of protons (hydrogen ions) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
15993	molecular hydrogen transport	P	The directed movement of molecular hydrogen (H2) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
15994	chlorophyll metabolic process	P	The chemical reactions and pathways involving chlorophyll, any compound of magnesium complexed in a porphyrin (tetrapyrrole) ring and which functions as a photosynthetic pigment.
15995	chlorophyll biosynthetic process	P	The chemical reactions and pathways resulting in the formation of chlorophyll, any compound of magnesium complexed in a porphyrin (tetrapyrrole) ring and which functions as a photosynthetic pigment, from less complex precursors.
15996	chlorophyll catabolic process	P	The chemical reactions and pathways resulting in the breakdown of chlorophyll, any compound of magnesium complexed in a porphyrin (tetrapyrrole) ring and which functions as a photosynthetic pigment, into less complex products.
16002	sulfite reductase activity	F	Catalysis of the reaction: hydrogen sulfide + acceptor + 3 H2O = sulfite + reduced acceptor.
16004	phospholipase activator activity	F	Increases the activity of a phospholipase, an enzyme that catalyzes of the hydrolysis of a glycerophospholipid.
16005	phospholipase A2 activator activity	F	Increases the activity of the enzyme phospholipase A2.
16006	Nebenkern	C	A product of the fusion of the mitochondria during spermatogenesis. After the completion of meiosis the mitochondria of the spermatid collect along side the nucleus and fuse into two masses; these wrap around each other to produce the spherical Nebenkern. During flagellum elongation the Nebenkern unfolds and the two derivatives (major and minor mitochondrial derivatives) elongate down the axoneme.
16007	mitochondrial derivative	C	The major and minor mitochondrial derivatives are the mitochondria of the sperm tail and derive by the unfolding of the Nebenkern during flagellum elongation.
16008	major mitochondrial derivative	C	The larger of the two mitochondrial derivatives that arise by the unfolding of the Nebenkern during flagellum elongation; the major mitochondrial derivative is ovoid and darker than the minor derivative.
16009	minor mitochondrial derivative	C	The smaller of the two mitochondrial derivatives that arise by the unfolding of the Nebenkern during flagellum elongation.
16010	dystrophin-associated glycoprotein complex	C	A multiprotein complex that forms a strong mechanical link between the cytoskeleton and extracellular matrix; typical of, but not confined to, muscle cells. The complex is composed of transmembrane, cytoplasmic, and extracellular proteins, including dystrophin, sarcoglycans, dystroglycan, dystrobrevins, syntrophins, sarcospan, caveolin-3, and NO synthase.
16011	dystroglycan complex	C	A protein complex that includes alpha- and beta-dystroglycan, which are alternative products of the same gene; the laminin-binding component of the dystrophin-associated glycoprotein complex, providing a link between the subsarcolemmal cytoskeleton (in muscle cells) and the extracellular matrix. Alpha-dystroglycan is an extracellular protein binding to alpha-laminin and to beta-dystroglycan; beta-dystroglycan is a transmembrane protein which binds alpha-dystroglycan and dystrophin.
16012	sarcoglycan complex	C	A protein complex formed of four sarcoglycans plus sarcospan; there are six known sarcoglycans: alpha-, beta-, gamma-, delta-, epsilon- and zeta-sarcoglycan; all are N-glycosylated single-pass transmembrane proteins. The sarcoglycan-sarcospan complex is a subcomplex of the dystrophin glycoprotein complex, and is fixed to the dystrophin axis by a lateral association with the dystroglycan complex.
16013	syntrophin complex	C	A protein complex that includes alpha-, beta1-, beta2-syntrophins and syntrophin-like proteins; the syntrophin complex binds to the second half of the carboxy-terminal domain of dystrophin; also associates with neuronal nitric oxide synthase.
16014	dystrobrevin complex	C	A protein complex comprising alpha- and beta-dystrobrevin; forms part of the dystrophin glycoprotein complex.
16015	morphogen activity	F	Acts as a trigger for a pattern specification process when present at a specific concentration within a gradient.
16018	cyclosporin A binding	F	Interacting selectively and non-covalently with cyclosporin A, a cyclic undecapeptide that contains several N-methylated and unusual amino acids.
16019	peptidoglycan receptor activity	F	Combining with a peptidoglycan and transmitting the signal to initiate a change in cell activity.
16020	membrane	C	A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
16021	integral component of membrane	C	The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
16024	CDP-diacylglycerol biosynthetic process	P	The chemical reactions and pathways resulting in the formation of CDP-diacylglycerol, CDP-1,2-diacylglycerol, a substance composed of diacylglycerol in glycosidic linkage with cytidine diphosphate.
16027	inaD signaling complex	C	A complex of proteins that are involved in phototransduction and attached to the transient receptor potential (TRP) channel. The protein connections are mediated through inaD.
16028	rhabdomere	C	The specialized microvilli-containing organelle on the apical surfaces of a photoreceptor cell containing the visual pigment rhodopsin and most of the proteins involved in phototransduction.
16029	subrhabdomeral cisterna	C	A membrane-bounded compartment that is found at the base of the rhabdomere and contains stored calcium, InsP3 receptors and smooth endoplasmic reticulum Ca2+-ATPase.
16031	tRNA import into mitochondrion	P	The directed movement of tRNA, transfer ribonucleic acid, from the cytoplasm into a mitochondrion.
16032	viral process	P	A multi-organism process in which a virus is a participant. The other participant is the host. Includes infection of a host cell, replication of the viral genome, and assembly of progeny virus particles. In some cases the viral genetic material may integrate into the host genome and only subsequently, under particular circumstances, 'complete' its life cycle.
16034	maleylacetoacetate isomerase activity	F	Catalysis of the reaction: 4-maleylacetoacetate = 4-fumarylacetoacetate.
16035	zeta DNA polymerase complex	C	A heterodimeric DNA polymerase complex that catalyzes error-prone DNA synthesis in contexts such as translesion synthesis and double-stranded break repair. First characterized in Saccharomyces, in which the subunits are Rev3p and Rev7p; a third protein, Rev1p, is often associated with the polymerase dimer.
16036	cellular response to phosphate starvation	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of phosphate.
16037	light absorption	P	The reception of a photon by a cell.
16038	absorption of visible light	P	The reception of a (visible light) photon by a cell, visible light being defined as having a wavelength within the range 380-780 nm.
16039	absorption of UV light	P	The reception of a (UV light) photon by a cell, UV light being defined as having a wavelength within the range 13.6-400 nm.
16040	glutamate synthase (NADH) activity	F	Catalysis of the reaction: 2 L-glutamate + NAD(+) = 2-oxoglutarate + L-glutamine + H(+) + NADH.
16041	glutamate synthase (ferredoxin) activity	F	Catalysis of the reaction: 2 L-glutamate + 2 oxidized ferredoxin = L-glutamine + 2-oxoglutarate + 2 reduced ferredoxin + 2 H+. This is a two-step reaction: (a) L-glutamate + NH3 = L-glutamine + H2O, (b) L-glutamate + 2 oxidized ferredoxin + H2O = NH3 + 2-oxoglutarate + 2 reduced ferredoxin + 2 H+.
16042	lipid catabolic process	P	The chemical reactions and pathways resulting in the breakdown of lipids, compounds soluble in an organic solvent but not, or sparingly, in an aqueous solvent.
16043	cellular component organization	P	A process that results in the assembly, arrangement of constituent parts, or disassembly of a cellular component.
16045	detection of bacterium	P	The series of events in which a stimulus from a bacterium is received and converted into a molecular signal.
16046	detection of fungus	P	The series of events in which a stimulus from a fungus is received and converted into a molecular signal.
16047	detection of parasitic fungus	P	The series of events in which a stimulus from a parasitic fungus (a fungus which spends all or part of its life in or on another organism from which it obtains nourishment and/or protection) is received and converted into a molecular signal.
16048	detection of temperature stimulus	P	The series of events in which a temperature stimulus (hot or cold) is received and converted into a molecular signal.
16049	cell growth	P	The process in which a cell irreversibly increases in size over time by accretion and biosynthetic production of matter similar to that already present.
16050	vesicle organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a vesicle.
16051	carbohydrate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y.
16052	carbohydrate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y.
16053	organic acid biosynthetic process	P	The chemical reactions and pathways resulting in the formation of organic acids, any acidic compound containing carbon in covalent linkage.
16054	organic acid catabolic process	P	The chemical reactions and pathways resulting in the breakdown of organic acids, any acidic compound containing carbon in covalent linkage.
16055	Wnt signaling pathway	P	The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell and ending with a change in cell state.
16056	rhodopsin mediated signaling pathway	P	The series of molecular signals generated as a consequence of excitation of rhodopsin by a photon and the events that convert the absorbed photons into a cellular response.
16057	regulation of membrane potential in photoreceptor cell	P	Hyperpolarization (vertebrates) or depolarization (invertebrates) of the photoreceptor cell membrane via closing/opening of cation specific channels as a result of signals generated by rhodopsin activation by a photon.
16058	maintenance of membrane potential in photoreceptor cell by rhodopsin mediated signaling	P	Maintenance of the excited state of a photoreceptor cell to produce a steady-state current as a result of signals generated by rhodopsin activation by a photon.
16059	deactivation of rhodopsin mediated signaling	P	The process of restoring the photoreceptor cell to its unexcited state after termination of the stimulus (photon).
16060	metarhodopsin inactivation	P	The process in which metarhodopsin is prevented from generating molecular signals. Activated rhodopsin (R*) is inactivated by a two-step process: first, R* is phosphorylated by rhodopsin kinase which lowers the activity of R*. Second, the protein arrestin binds to phosphorylated R* to de-activate it.
16061	regulation of light-activated channel activity	P	Any process that modulates the frequency, rate or extent of light-activated channel activity.
16062	adaptation of rhodopsin mediated signaling	P	The process in which a rhodopsin-mediated signaling pathway is adjusted to modulate the sensitivity and response of a visual system to light stimuli (that might vary over more than 6 magnitudes in intensity) without response saturation.
16063	rhodopsin biosynthetic process	P	The chemical reactions and pathways resulting in the formation of rhodopsin, a brilliant purplish-red, light-sensitive visual pigment found in the rod cells of the retinas.
16064	immunoglobulin mediated immune response	P	An immune response mediated by immunoglobulins, whether cell-bound or in solution.
16068	type I hypersensitivity	P	An inflammatory response driven by antigen recognition by antibodies bound to Fc receptors on mast cells or basophils, occurring within minutes after exposure of a sensitized individual to the antigen, and leading to the release of a variety of inflammatory mediators such as histamines.
16070	RNA metabolic process	P	The cellular chemical reactions and pathways involving RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage.
16071	mRNA metabolic process	P	The chemical reactions and pathways involving mRNA, messenger RNA, which is responsible for carrying the coded genetic 'message', transcribed from DNA, to sites of protein assembly at the ribosomes.
16072	rRNA metabolic process	P	The chemical reactions and pathways involving rRNA, ribosomal RNA, a structural constituent of ribosomes.
16073	snRNA metabolic process	P	The chemical reactions and pathways involving snRNA, small nuclear RNA, any of various low-molecular-mass RNA molecules found in the eukaryotic nucleus as components of the small nuclear ribonucleoprotein.
16074	snoRNA metabolic process	P	The chemical reactions and pathways involving snoRNA, small nucleolar RNA, any of a class of small RNAs that are associated with the eukaryotic nucleus as components of small nucleolar ribonucleoproteins. They participate in the processing or modifications of many RNAs, mostly ribosomal RNAs (rRNAs) though snoRNAs are also known to target other classes of RNA, including spliceosomal RNAs, tRNAs, and mRNAs via a stretch of sequence that is complementary to a sequence in the targeted RNA.
16075	rRNA catabolic process	P	The chemical reactions and pathways resulting in the breakdown of rRNA, ribosomal RNA, a structural constituent of ribosomes.
16076	snRNA catabolic process	P	The chemical reactions and pathways resulting in the breakdown of snRNA, small nuclear RNA, low-molecular-mass RNA molecules found in the eukaryotic nucleus as components of the small nuclear ribonucleoprotein.
16077	snoRNA catabolic process	P	The chemical reactions and pathways resulting in the breakdown of snoRNA, small nucleolar RNA, any of a class of small RNAs that are associated with the eukaryotic nucleus as components of small nucleolar ribonucleoproteins.
16078	tRNA catabolic process	P	The chemical reactions and pathways resulting in the breakdown of tRNA, transfer RNA, a class of relatively small RNA molecules responsible for mediating the insertion of amino acids into the sequence of nascent polypeptide chains during protein synthesis.
16079	synaptic vesicle exocytosis	P	Fusion of intracellular membrane-bounded vesicles with the pre-synaptic membrane of the neuronal cell resulting in release of neurotransmitter into the synaptic cleft.
16080	synaptic vesicle targeting	P	The process in which synaptic vesicles are directed to specific destination membranes, mediated by molecules at the vesicle membrane and target membrane surfaces.
16081	synaptic vesicle docking	P	The initial (indirect) attachment of a synaptic vesicle membrane to the presynaptic active zone membrane, mediated by proteins protruding from the membrane and proteins of the presynaptic active zone cytoplasmic component. Synaptic vesicle tethering is the first step in this process.
16082	synaptic vesicle priming	P	The formation of SNARE-containing complexes, bringing synaptic vesicle membrane and plasma membranes into close proximity and thereby facilitating membrane fusion.
16084	myostimulatory hormone activity	F	The action characteristic of myostimulatory hormone, a peptide hormone that stimulates muscle contraction.
16085	myoinhibitory hormone activity	F	The action characteristic of myostimulatory hormone, a peptide hormone that inhibits muscle contraction.
16087	ecdysiostatic hormone activity	F	The action characteristic of ecdysiostatic hormone, a peptide hormone that inhibits ecdysone secretion.
16090	prenol metabolic process	P	The chemical reactions and pathways involving prenols, isoprenoids of general formula (H-CH2-C(CH3)=CH-CH2-)n-OH, any primary monohydroxy alcohol whose carbon skeleton consists of two or more isoprenoid residues linked head to tail.
16091	prenol biosynthetic process	P	The chemical reactions and pathways resulting in the formation of prenols, isoprenoids of general formula (H-CH2-C(CH3)=CH-CH2-)n-OH, any primary monohydroxy alcohol whose carbon skeleton consists of two or more isoprenoid residues linked head to tail.
16092	prenol catabolic process	P	The chemical reactions and pathways resulting in the breakdown of prenols, isoprenoids of general formula (H-CH2-C(CH3)=CH-CH2-)n-OH, any primary monohydroxy alcohol whose carbon skeleton consists of two or more isoprenoid residues linked head to tail.
16093	polyprenol metabolic process	P	The chemical reactions and pathways involving polyprenols, prenols with more than 4 isoprenoid residues, which may be all-trans, or a mixture of cis and trans.
16094	polyprenol biosynthetic process	P	The chemical reactions and pathways resulting in the formation of polyprenols, prenols with more than 4 isoprenoid residues, which may be all-trans, or a mixture of cis and trans.
16095	polyprenol catabolic process	P	The chemical reactions and pathways resulting in the breakdown of polyprenols, prenols with more than 4 isoprenoid residues, which may be all-trans, or a mixture of cis and trans.
16098	monoterpenoid metabolic process	P	The chemical reactions and pathways involving monoterpenoid compounds, terpenoids having a C10 skeleton.
16099	monoterpenoid biosynthetic process	P	The chemical reactions and pathways resulting in the formation of monoterpenoid compounds, terpenoids having a C10 skeleton.
16100	monoterpenoid catabolic process	P	The chemical reactions and pathways resulting in the breakdown of monoterpenoid compounds, terpenoids having a C10 skeleton.
16101	diterpenoid metabolic process	P	The chemical reactions and pathways involving diterpenoid compounds, terpenoids with four isoprene units.
16102	diterpenoid biosynthetic process	P	The chemical reactions and pathways resulting in the formation of diterpenoid compounds, terpenoids with four isoprene units.
16103	diterpenoid catabolic process	P	The chemical reactions and pathways resulting in the breakdown of diterpenoid compounds, terpenoids with four isoprene units.
16104	triterpenoid biosynthetic process	P	The chemical reactions and pathways resulting in the formation of triterpenoid compounds, terpenoids with six isoprene units.
16105	triterpenoid catabolic process	P	The chemical reactions and pathways resulting in the breakdown of triterpenoid compounds, terpenoids with six isoprene units.
16106	sesquiterpenoid biosynthetic process	P	The chemical reactions and pathways resulting in the formation of sesquiterpenoid compounds, terpenoids with three isoprene units.
16107	sesquiterpenoid catabolic process	P	The chemical reactions and pathways resulting in the breakdown of sesquiterpenoid compounds, terpenoids with three isoprene units.
16108	tetraterpenoid metabolic process	P	The chemical reactions and pathways involving tetraterpenoid compounds, terpenoids with eight isoprene units.
16109	tetraterpenoid biosynthetic process	P	The chemical reactions and pathways resulting in the formation of tetraterpenoid compounds, terpenoids with eight isoprene units.
16110	tetraterpenoid catabolic process	P	The chemical reactions and pathways resulting in the breakdown of tetraterpenoid compounds, terpenoids with eight isoprene units.
16111	polyterpenoid metabolic process	P	The chemical reactions and pathways involving polyterpenoid compounds, terpenoids with more than eight isoprene units.
16112	polyterpenoid biosynthetic process	P	The chemical reactions and pathways resulting in the formation of polyterpenoid compounds, terpenoids with more than eight isoprene units.
16113	polyterpenoid catabolic process	P	The chemical reactions and pathways resulting in the breakdown of polyterpenoid compounds, terpenoids with more than eight isoprene units.
16114	terpenoid biosynthetic process	P	The chemical reactions and pathways resulting in the formation of terpenoids, any member of a class of compounds characterized by an isoprenoid chemical structure.
16115	terpenoid catabolic process	P	The chemical reactions and pathways resulting in the breakdown of terpenoids, any member of a class of compounds characterized by an isoprenoid chemical structure.
16116	carotenoid metabolic process	P	The chemical reactions and pathways involving carotenoids, tetraterpenoid compounds in which two units of 4 isoprenoid residues joined head-to-tail are themselves joined tail-to-tail.
16117	carotenoid biosynthetic process	P	The chemical reactions and pathways resulting in the formation of carotenoids, tetraterpenoid compounds in which two units of 4 isoprenoid residues joined head-to-tail are themselves joined tail-to-tail.
16118	carotenoid catabolic process	P	The chemical reactions and pathways resulting in the breakdown of carotenoids, tetraterpenoid compounds in which two units of 4 isoprenoid residues joined head-to-tail are themselves joined tail-to-tail.
16119	carotene metabolic process	P	The chemical reactions and pathways involving carotenes, hydrocarbon carotenoids.
16120	carotene biosynthetic process	P	The chemical reactions and pathways resulting in the formation of carotenes, hydrocarbon carotenoids.
16121	carotene catabolic process	P	The chemical reactions and pathways resulting in the breakdown of carotenes, hydrocarbon carotenoids.
16122	xanthophyll metabolic process	P	The chemical reactions and pathways involving xanthophylls, oxygen-containing carotenoids.
16123	xanthophyll biosynthetic process	P	The chemical reactions and pathways resulting in the formation of xanthophylls, oxygen-containing carotenoids.
16124	xanthophyll catabolic process	P	The chemical reactions and pathways resulting in the breakdown of xanthophylls, oxygen-containing carotenoids.
16125	sterol metabolic process	P	The chemical reactions and pathways involving sterols, steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule.
16126	sterol biosynthetic process	P	The chemical reactions and pathways resulting in the formation of sterols, steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule.
16127	sterol catabolic process	P	The chemical reactions and pathways resulting in the breakdown of sterols, steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule.
16128	phytosteroid metabolic process	P	The chemical reactions and pathways involving phytosteroids, steroids of higher plants that differ from animal steroids in having substitutions at C24 and/or a double bond at C22. Phytosteroids are so named because they occur in higher plants; some, notably ergosterol, are also found in fungi.
16129	phytosteroid biosynthetic process	P	The chemical reactions and pathways resulting in the formation of phytosteroids, steroids that differ from animal steroids in having substitutions at C24 and/or a double bond at C22. Phytosteroids are so named because they occur in higher plants; some, notably ergosterol, are also found in fungi.
16130	phytosteroid catabolic process	P	The chemical reactions and pathways resulting in the breakdown of phytosteroids, steroids that differ from animal steroids in having substitutions at C24 and/or a double bond at C22. Phytosteroids are so named because they occur in higher plants; some, notably ergosterol, are also found in fungi.
16131	brassinosteroid metabolic process	P	The chemical reactions and pathways involving brassinosteroids, any of a group of steroid derivatives that occur at very low concentrations in plant tissues and may have hormone-like effects.
16132	brassinosteroid biosynthetic process	P	The chemical reactions and pathways resulting in the formation of brassinosteroids, any of a group of steroid derivatives that occur at very low concentrations in plant tissues and may have hormone-like effects.
16133	brassinosteroid catabolic process	P	The chemical reactions and pathways resulting in the breakdown of brassinosteroids, any of a group of steroid derivatives that occur at very low concentrations in plant tissues and may have hormone-like effects.
16134	saponin metabolic process	P	The chemical reactions and pathways involving saponins, glycosides of plants in which the aglycan (sapogenin) group is a terpene or steroid and the sugar group is a glucose, a galactose, a pentose, a methylpentose or an oligosaccharide. Saponins are powerful surfactant agents and membrane active; they are, hence, toxic to animals on injection.
16135	saponin biosynthetic process	P	The chemical reactions and pathways resulting in the formation of saponins, glycosides of plants in which the aglycan (sapogenin) group is a terpene or steroid and the sugar group is a glucose, a galactose, a pentose, a methylpentose or an oligosaccharide. Saponins are powerful surfactant agents and membrane active; they are, hence, toxic to animals on injection.
16136	saponin catabolic process	P	The chemical reactions and pathways resulting in the breakdown of saponins, glycosides of plants in which the aglycan (sapogenin) group is a terpene or steroid and the sugar group is a glucose, a galactose, a pentose, a methylpentose or an oligosaccharide. Saponins are powerful surfactant agents and membrane active; they are, hence, toxic to animals on injection.
16137	glycoside metabolic process	P	The chemical reactions and pathways involving glycosides, compounds in which a glycosyl group is substituted into a hydroxyl, thiol or selenol group in another compound.
16138	glycoside biosynthetic process	P	The chemical reactions and pathways resulting in the formation of glycosides, compounds in which a glycosyl group is substituted into a hydroxyl, thiol or selenol group in another compound.
16139	glycoside catabolic process	P	The chemical reactions and pathways resulting in the breakdown of glycosides, compounds in which a glycosyl group is substituted into a hydroxyl, thiol or selenol group in another compound.
16143	S-glycoside metabolic process	P	The chemical reactions and pathways involving S-glycosides, any compound in which a glycosyl group has been substituted into a thiol group.
16144	S-glycoside biosynthetic process	P	The chemical reactions and pathways resulting in the formation of S-glycosides, any compound in which a glycosyl group has been substituted into a thiol group.
16145	S-glycoside catabolic process	P	The chemical reactions and pathways resulting in the breakdown of S-glycosides, any compound in which a glycosyl group has been substituted into a thiol group.
16149	translation release factor activity, codon specific	F	A translation release factor that is specific for one or more particular termination codons; acts at the ribosomal A-site and require polypeptidyl-tRNA at the P-site.
16150	translation release factor activity, codon nonspecific	F	A translation release factor that is not specific to particular codons; binds to guanine nucleotides.
16151	nickel cation binding	F	Interacting selectively and non-covalently with nickel (Ni) cations.
16152	mercury (II) reductase activity	F	Catalysis of the reaction: H(+) + Hg + NADP(+) = Hg(2+) + NADPH.
16153	urocanate hydratase activity	F	Catalysis of the reaction: 4-imidazolone-5-propanoate + H(+) = trans-urocanate + H(2)O.
16154	pyrimidine-nucleoside phosphorylase activity	F	Catalysis of the reaction: pyrimidine nucleoside + phosphate = pyrimidine + alpha-D-ribose 1-phosphate.
16155	formyltetrahydrofolate dehydrogenase activity	F	Catalysis of the reaction: 10-formyltetrahydrofolate + H(2)O + NADP(+) = (6S)-5,6,7,8-tetrahydrofolate + CO(2) + H(+) + NADPH.
16156	fumarate reductase (NADH) activity	F	Catalysis of the reaction: NAD(+) + succinate = fumarate + H(+) + NADH.
16157	sucrose synthase activity	F	Catalysis of the reaction: UDP-glucose + D-fructose = UDP + sucrose.
16158	3-phytase activity	F	Catalysis of the reaction: myo-inositol hexakisphosphate + H2O = D-myo-inositol 1,2,4,5,6-pentakisphosphate + phosphate.
16159	muconolactone delta-isomerase activity	F	Catalysis of the reaction: 2,5-dihydro-5-oxofuran-2-acetate = 3,4-dihydro-5-oxofuran-2-acetate.
16160	amylase activity	F	Catalysis of the hydrolysis of amylose or an amylose derivative.
16161	beta-amylase activity	F	Catalysis of the reaction: (1,4-alpha-D-glucosyl)(n+1) + H2O = (1,4-alpha-D-glucosyl)(n-1) + alpha-maltose. This reaction is the hydrolysis of 1,4-alpha-glucosidic linkages in polysaccharides so as to remove successive maltose units from the non-reducing ends of the chains.
16162	cellulose 1,4-beta-cellobiosidase activity	F	Catalysis of the hydrolysis of (1->4)-beta-D-glucosidic linkages in cellulose and cellotetraose, releasing cellobiose from the non-reducing ends of the chains.
16163	nitrogenase activity	F	Catalysis of the reaction: 8 reduced ferredoxin + 8 H+ + nitrogen + 16 ATP = 8 oxidized ferredoxin + 2 NH3 + 16 ADP + 16 phosphate.
16165	linoleate 13S-lipoxygenase activity	F	Catalysis of the reaction: linoleate + O2 = (9Z,11E)-(13S)-13-hydroperoxyoctadeca-9,11-dienoate.
16166	phytoene dehydrogenase activity	F	Catalysis of the dehydrogenation of phytoene to produce a carotenoid intermediate such as phytofluene.
16167	glial cell-derived neurotrophic factor receptor activity	F	Combining with glial cell line-derived neurotrophic factor and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
16168	chlorophyll binding	F	Interacting selectively and non-covalently with chlorophyll; any compound of magnesium complexed in a porphyrin (tetrapyrrole) ring and which functions as a photosynthetic pigment.
16169	bacteriochlorophyll c binding	F	Interacting selectively and non-covalently with bacteriochlorophyll c, a chlorophyll of photosynthetic bacteria, for example green sulfur bacteria.
16170	interleukin-15 receptor binding	F	Interacting selectively and non-covalently with the interleukin-15 receptor.
16174	NAD(P)H oxidase activity	F	Catalysis of the reaction: NAD(P)H + H+ + O2 = NAD(P)+ + hydrogen peroxide.
16175	superoxide-generating NADPH oxidase activity	F	Catalysis of the reaction: NAD(P)H + O2 = NAD(P)H + O2-.
16176	superoxide-generating NADPH oxidase activator activity	F	Increases the activity of the enzyme superoxide-generating NADPH oxidase.
16180	snRNA processing	P	Any process involved in the conversion of a primary small nuclear RNA (snRNA) transcript into a mature snRNA molecule.
16182	synaptic vesicle budding from endosome	P	Budding of synaptic vesicles during the formation of constitutive recycling vesicles from early endosomes.
16183	synaptic vesicle coating	P	The formation of clathrin coated pits in the presynaptic membrane endocytic zone, triggered by the presence of high concentrations of synaptic vesicle components. This process leads to, but does not include budding of the membrane to form new vesicles.
16185	synaptic vesicle budding from presynaptic endocytic zone membrane	P	Evagination of the presynaptic membrane, resulting in the formation of a new synaptic vesicle.
16188	synaptic vesicle maturation	P	Steps required to form an initiated synaptic vesicle into a fully formed and transmissible synaptic vesicle.
16189	synaptic vesicle to endosome fusion	P	Fusion of a synaptic vesicle with an endosome.
16191	synaptic vesicle uncoating	P	The removal of the protein coat on a synaptic vesicle following the pinching step at the end of budding from the presynaptic membrane.
16192	vesicle-mediated transport	P	A cellular transport process in which transported substances are moved in membrane-bounded vesicles; transported substances are enclosed in the vesicle lumen or located in the vesicle membrane. The process begins with a step that directs a substance to the forming vesicle, and includes vesicle budding and coating. Vesicles are then targeted to, and fuse with, an acceptor membrane.
16197	endosomal transport	P	The directed movement of substances into, out of, or mediated by an endosome, a membrane-bounded organelle that carries materials newly ingested by endocytosis. It passes many of the materials to lysosomes for degradation.
16198	axon choice point recognition	P	The recognition of molecules at a choice point by an axon growth cone; at a choice point the growth cone determines the direction of its future growth.
16199	axon midline choice point recognition	P	The recognition of molecules at the central nervous system midline choice point by an axon growth cone; this choice point determines whether the growth cone will cross the midline.
16200	synaptic target attraction	P	The process in which a neuronal cell in a multicellular organism recognizes chemoattractant signals from, and grows towards, potential targets.
16201	synaptic target inhibition	P	The process in which a neuronal cell in a multicellular organism recognizes chemorepellent signals that inhibit its growth toward the source.
16202	regulation of striated muscle tissue development	P	Any process that modulates the frequency, rate or extent of striated muscle development.
16203	muscle attachment	P	The developmental process in which a skeletal muscle attaches to its target (such as bone or body wall).
16204	determination of muscle attachment site	P	The process that mediates the transfer of information from the cells of a muscle to those of its intended target, thereby identifying the target site.
16205	selenocysteine methyltransferase activity	F	Catalysis of the reaction: selenocysteine + S-adenosyl-L-methionine = Se-methylselenocysteine + S-adenosyl-homocysteine.
16206	catechol O-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + a catechol = S-adenosyl-L-homocysteine + a guaiacol.
16207	4-coumarate-CoA ligase activity	F	Catalysis of the reaction: ATP + 4-coumarate + CoA = AMP + diphosphate + 4-coumaroyl-CoA.
16208	AMP binding	F	Interacting selectively and non-covalently with AMP, adenosine monophosphate.
16209	antioxidant activity	F	Inhibition of the reactions brought about by dioxygen (O2) or peroxides. Usually the antioxidant is effective because it can itself be more easily oxidized than the substance protected. The term is often applied to components that can trap free radicals, thereby breaking the chain reaction that normally leads to extensive biological damage.
16210	naringenin-chalcone synthase activity	F	Catalysis of the reaction: 3 malonyl-CoA + 4-coumaroyl-CoA = 4 CoA + naringenin chalcone + 3 CO2.
16211	ammonia ligase activity	F	Catalysis of the ligation of ammonia (NH3) to another substance via a carbon-nitrogen bond with concomitant breakage of a diphosphate linkage, usually in a nucleoside triphosphate.
16212	kynurenine-oxoglutarate transaminase activity	F	Catalysis of the reaction: L-kynurenine + 2-oxoglutarate = 4-(2-aminophenyl)-2,4-dioxobutanoate + L-glutamate.
16213	linoleoyl-CoA desaturase activity	F	Catalysis of the reaction: linoleoyl-CoA + reduced acceptor + O2 = gamma-linolenoyl-CoA + acceptor + 2 H2O.
16215	acyl-CoA desaturase activity	F	Catalysis of the reaction: acyl-CoA + reduced acceptor + O2 = desaturated-acyl-CoA + acceptor + 2 H2O.
16216	isopenicillin-N synthase activity	F	Catalysis of the reaction: N-[(5S)-5-amino-5-carboxypentanoyl]-L-cysteinyl-D-valine + O(2) = 2 H(2)O + isopenicillin N.
16217	N-ethylammeline chlorohydrolase activity	F	Catalysis of the reaction: deethylsimazine + H2O = N-ethylammeline + chloride + H+.
16222	procollagen-proline 4-dioxygenase complex	C	A protein complex that catalyzes the formation of procollagen trans-4-hydroxy-L-proline and succinate from procollagen L-proline and 2-oxoglutarate, requiring Fe2+ and ascorbate. Contains two alpha subunits that contribute to most parts of the catalytic sites, and two beta subunits that are identical to protein-disulfide isomerase.
16223	beta-alanine-pyruvate transaminase activity	F	Catalysis of the reaction: L-alanine + 2-oxopropanoate = pyruvate + beta-alanine.
16226	iron-sulfur cluster assembly	P	The incorporation of iron and exogenous sulfur into a metallo-sulfur cluster.
16229	steroid dehydrogenase activity	F	Catalysis of an oxidation-reduction (redox) reaction in which one substrate is a sterol derivative.
16230	sphingomyelin phosphodiesterase activator activity	F	Increases the activity of the enzyme sphingomyelin phosphodiesterase.
16231	beta-N-acetylglucosaminidase activity	F	Catalysis of the hydrolysis of terminal non-reducing N-acetyl-D-glucosamine residues in N-acetyl-beta-D-glucosaminides.
16232	HNK-1 sulfotransferase activity	F	Catalysis of the synthesis of the HKK-1 carbohydrate epitope; adds a sulfate group to a precursor, GlcA-beta-(1->3)-Gal-beta-(1->4)-GlcNAc-beta-(1->R), forming sulfo-3GlcA-beta-(1->3)-Gal-beta-(1->4)-GlcNAc-beta-(1->R).
16233	telomere capping	P	A process in which telomeres are protected from degradation and fusion, thereby ensuring chromosome stability by protecting the ends from both degradation and from being recognized as damaged DNA. May be mediated by specific single- or double-stranded telomeric DNA binding proteins.
16234	inclusion body	C	A discrete intracellular part formed of aggregated molecules such as proteins or other biopolymers.
16235	aggresome	C	An inclusion body formed by dynein-dependent retrograde transport of an aggregated protein on microtubules.
16236	macroautophagy	P	The major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane-bounded autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane-bounded structure. Autophagosomes then fuse with a lysosome (or vacuole) releasing single-membrane-bounded autophagic bodies that are then degraded within the lysosome (or vacuole). Though once thought to be a purely non-selective process, it appears that some types of macroautophagy, e.g. macropexophagy, macromitophagy, may involve selective targeting of the targets to be degraded.
16237	lysosomal microautophagy	P	The transfer of cytosolic components into the lysosomal compartment by direct invagination of the lysosomal membrane without prior sequestration into an autophagosome. The engulfing membranes fuse, resulting in the lysosomal delivery of the cargo wrapped in a single membrane derived from the invaginated lysosomal membrane. In S. cerevisiae, the vacuole is the lysosomal compartment.
16239	positive regulation of macroautophagy	P	Any process, such as recognition of nutrient depletion, that activates or increases the rate of macroautophagy to bring cytosolic macromolecules to the vacuole/lysosome for degradation.
16240	autophagosome docking	P	The initial attachment of an autophagosome membrane to the target membrane, mediated by proteins protruding from the membrane of the vesicle and the target membrane. Docking requires only that the two membranes come close enough for these proteins to interact and adhere.
16241	regulation of macroautophagy	P	Any process that modulates the frequency, rate or extent of macroautophagy.
16242	negative regulation of macroautophagy	P	Any process that stops, prevents, or reduces the frequency, rate or extent of macroautophagy.
16243	regulation of autophagosome size	P	Any process that modulates the size of the autophagosome.
16246	RNA interference	P	The process in which double-stranded RNAs silence cognate genes. Involves posttranscriptional gene inactivation ('silencing') both of transgenes or dsRNA introduced into a germline, and of the host gene(s) homologous to the transgenes or dsRNA. This silencing is triggered by the introduction of transgenes or double-stranded RNA (dsRNA), and can occur through a specific decrease in the level of mRNA, or by negative regulation of translation, of both host genes and transgenes.
16247	channel regulator activity	F	Modulates the activity of a channel. A channel catalyzes energy-independent facilitated diffusion, mediated by passage of a solute through a transmembrane aqueous pore or channel.
16248	channel inhibitor activity	F	Stops, prevents, or reduces the activity of a channel via direct interaction with the channel. A channel catalyzes energy-independent facilitated diffusion, mediated by passage of a solute through a transmembrane aqueous pore or channel.
16250	N-sulfoglucosamine sulfohydrolase activity	F	Catalysis of the reaction: N-sulfo-D-glucosamine + H2O = D-glucosamine + sulfate.
16254	preassembly of GPI anchor in ER membrane	P	The stepwise addition of the components of the GPI anchor on to phosphatidylinositol lipids in the endoplasmic reticulum membrane.
16255	attachment of GPI anchor to protein	P	A transamidation reaction that results in the cleavage of the polypeptide chain and the concomitant transfer of the GPI anchor to the newly formed carboxy-terminal amino acid of the anchored protein. The cleaved C-terminal contains the C-terminal GPI signal sequence of the newly synthesized polypeptide chain.
16256	N-glycan processing to lysosome	P	The modification of high-mannose N-glycans by UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase and the subsequent removal of the N-acetylglucosamine residues yielding mannose-6-P that occurs in the ER-Golgi apparatus to N-glycans destined for the lysosome.
16257	N-glycan processing to secreted and cell-surface N-glycans	P	The modification of high-mannose (Man9-Asn) N-glycans by mannosyl-oligosaccharide 1,2-alpha-mannosidase. This may result in Man8GlcNAc2-Asn N-glycans (which in yeast may be subsequently modified by the addition of further mannose residues) or Man5GlcNAc2-Asn N-glycans that are substrates for further diversification in the Golgi apparatus.
16258	N-glycan diversification	P	The generation, in the Golgi apparatus, of side chain diversity from high mannose Man5GlcNAc2-Asn N-glycans by specific glycosyltransferases and glycosidases.
16259	selenocysteine metabolic process	P	The chemical reactions and pathways involving selenocysteine, an essential component of glutathione peroxidase and some other proteins.
16260	selenocysteine biosynthetic process	P	The chemical reactions and pathways resulting in the formation of selenocysteine, an essential component of glutathione peroxidase and some other proteins.
16261	selenocysteine catabolic process	P	The chemical reactions and pathways resulting in the breakdown of selenocysteine, an essential component of glutathione peroxidase and some other proteins.
16262	protein N-acetylglucosaminyltransferase activity	F	Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + protein = UDP + 4-N-(N-acetyl-D-glucosaminyl)-protein.
16263	glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity	F	Catalysis of the addition of a galactosyl residue to a non-reducing O-linked N-acetylgalactosamine residue in an O-glycan.
16264	gap junction assembly	P	Assembly of gap junctions, which are found in most animal tissues, and serve as direct connections between the cytoplasms of adjacent cells. They provide open channels through the plasma membrane, allowing ions and small molecules (less than approximately a thousand daltons) to diffuse freely between neighboring cells, but preventing the passage of proteins and nucleic acids.
16266	O-glycan processing	P	The stepwise addition of carbohydrate or carbohydrate derivative residues to the initially added O-linked residue (usually GalNAc) to form a core O-glycan structure.
16267	O-glycan processing, core 1	P	The stepwise addition of carbohydrate or carbohydrate derivative residues to the initially added O-linked residue (usually GalNAc) to form the core 1 O-glycan structure, Gal-beta-(1->3)-GalNAc.
16268	O-glycan processing, core 2	P	The stepwise addition of carbohydrate or carbohydrate derivative residues to the initially added O-linked residue (usually GalNAc) to form the core 2 O-glycan structure, GlcNAc-beta-(1->6)[Gal-beta-(1->3)]-GalNAc.
16269	O-glycan processing, core 3	P	The stepwise addition of carbohydrate or carbohydrate derivative residues to the initially added O-linked residue (usually GalNAc) to form the core 3 O-glycan structure, GlcNAc-beta-(1->3)-GalNAc.
16270	O-glycan processing, core 4	P	The stepwise addition of carbohydrate or carbohydrate derivative residues to the initially added O-linked residue (usually GalNAc) to form the core 4 O-glycan structure, GlcNAc-beta-(1->6)[GalNAc-beta-(1->3)]-GalNAc.
16272	prefoldin complex	C	A multisubunit chaperone that is capable of delivering unfolded proteins to cytosolic chaperonin, which it acts as a cofactor for. In humans, the complex is a heterohexamer of two PFD-alpha and four PFD-beta type subunits. In Saccharomyces cerevisiae, it also acts in the nucleus to regulate the rate of elongation by RNA polymerase II via a direct effect on histone dynamics.
16273	arginine N-methyltransferase activity	F	Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to an amino group of an arginine residue.
16274	protein-arginine N-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + (protein)-arginine = S-adenosyl-L-homocysteine + (protein)-N-methyl-arginine.
16275	[cytochrome c]-arginine N-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + (cytochrome c)-arginine = S-adenosyl-L-homocysteine + (cytochrome c)-N(omega)-methyl-arginine.
16277	[myelin basic protein]-arginine N-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + (myelin basic protein)-arginine = S-adenosyl-L-homocysteine + (myelin basic protein)-N(omega)-methyl-arginine.
16278	lysine N-methyltransferase activity	F	Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to the epsilon-amino group of a lysine residue.
16279	protein-lysine N-methyltransferase activity	F	Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to the epsilon-amino group of a lysine residue in a protein substrate.
16281	eukaryotic translation initiation factor 4F complex	C	The eukaryotic translation initiation factor 4F complex is composed of eIF4E, eIF4A and eIF4G; it is involved in the recognition of the mRNA cap, ATP-dependent unwinding of the 5'-terminal secondary structure and recruitment of the mRNA to the ribosome.
16282	eukaryotic 43S preinitiation complex	C	A protein complex composed of the 40S ribosomal subunit plus eIF1A, eIF3, and eIF2-GTP-bound methionyl-initiator methionine tRNA.
16286	small conductance calcium-activated potassium channel activity	F	Enables the transmembrane transfer of potassium by a channel with a unit conductance of 2 to 20 picoSiemens that opens in response to stimulus by internal calcium ions. Small conductance calcium-activated potassium channels are more sensitive to calcium than are large conductance calcium-activated potassium channels. Transport by a channel involves catalysis of facilitated diffusion of a solute (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel, without evidence for a carrier-mediated mechanism.
16287	glycerone-phosphate O-acyltransferase activity	F	Catalysis of the reaction: acyl-CoA + glycerone phosphate = 1-acylglycerone 3-phosphate + CoA.
16289	CoA hydrolase activity	F	Catalysis of the reaction: X-CoA + H2O = X + CoA; X may be any group.
16290	palmitoyl-CoA hydrolase activity	F	Catalysis of the reaction: palmitoyl-CoA + H2O = CoA + palmitate.
16295	myristoyl-[acyl-carrier-protein] hydrolase activity	F	Catalysis of the reaction: myristoyl-[acyl-carrier protein] + H2O = [acyl-carrier protein] + myristate.
16296	palmitoyl-[acyl-carrier-protein] hydrolase activity	F	Catalysis of the reaction: palmitoyl-[acyl-carrier protein] + H2O = [acyl-carrier protein] + palmitate.
16297	acyl-[acyl-carrier-protein] hydrolase activity	F	Catalysis of the reaction: acyl-[acyl-carrier protein] + H2O = [acyl-carrier protein] + a fatty acid.
16298	lipase activity	F	Catalysis of the hydrolysis of a lipid or phospholipid.
16300	tRNA (uracil) methyltransferase activity	F	Catalysis of the transfer of a methyl group from a donor to a uracil residue in a tRNA molecule.
16301	kinase activity	F	Catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule.
16303	1-phosphatidylinositol-3-kinase activity	F	Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol + ATP = a 1-phosphatidyl-1D-myo-inositol 3-phosphate + ADP + 2 H(+).
16307	phosphatidylinositol phosphate kinase activity	F	Catalysis of the reaction: ATP + a phosphatidylinositol phosphate = ADP + a phosphatidylinositol bisphosphate.
16308	1-phosphatidylinositol-4-phosphate 5-kinase activity	F	Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 4-phosphate + ATP = 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + ADP + 2 H(+).
16309	1-phosphatidylinositol-5-phosphate 4-kinase activity	F	Catalysis of the reaction: ATP + 1-phosphatidyl-1D-myo-inositol 5-phosphate = ADP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate.
16310	phosphorylation	P	The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide.
16311	dephosphorylation	P	The process of removing one or more phosphoric (ester or anhydride) residues from a molecule.
16312	inositol bisphosphate phosphatase activity	F	Catalysis of the reaction: myo-inositol bisphosphate + H2O = myo-inositol phosphate + phosphate.
16314	phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity	F	Catalysis of the reaction: phosphatidylinositol-3,4,5-trisphosphate + H2O = phosphatidylinositol-4,5-bisphosphate + phosphate.
16316	phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity	F	Catalysis of the reaction: 1-phosphatidyl-myo-inositol 3,4-bisphosphate + H2O = 1-phosphatidyl-1D-myo-inositol 3-phosphate + phosphate.
16318	ommatidial rotation	P	The process in which photoreceptors are arranged in ommatidia in the dorsal and ventral fields to be mirror images. The polarity is established in the imaginal discs concurrently with cell fate specification.
16319	mushroom body development	P	The process whose specific outcome is the progression of the mushroom body over time, from its formation to the mature structure. The mushroom body is composed of the prominent neuropil structures of the insect central brain, thought to be crucial for olfactory associated learning. These consist mainly of a bulbous calyx and tightly packaged arrays of thin parallel fibers of the Kenyon cells.
16320	endoplasmic reticulum membrane fusion	P	The joining of 2 or more lipid bilayer membranes that surround the endoplasmic reticulum.
16321	female meiosis chromosome segregation	P	The cell cycle process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets during the meiotic cell cycle in a female.
16322	neuron remodeling	P	The developmentally regulated remodeling of neuronal projections such as pruning to eliminate the extra dendrites and axons projections set up in early stages of nervous system development.
16323	basolateral plasma membrane	C	The region of the plasma membrane that includes the basal end and sides of the cell. Often used in reference to animal polarized epithelial membranes, where the basal membrane is the part attached to the extracellular matrix, or in plant cells, where the basal membrane is defined with respect to the zygotic axis.
16324	apical plasma membrane	C	The region of the plasma membrane located at the apical end of the cell.
16325	oocyte microtubule cytoskeleton organization	P	Formation and maintenance of a polarized microtubule array originating from a microtubule-organizing center (MTOC) in the oocyte. An example of this is found in Drosophila melanogaster.
16327	apicolateral plasma membrane	C	The apical end of the lateral plasma membrane of epithelial cells.
16328	lateral plasma membrane	C	The portion of the plasma membrane at the lateral side of the cell. In epithelial cells, lateral plasma membranes are on the sides of cells which lie at the interface of adjacent cells.
16330	second mitotic wave involved in compound eye morphogenesis	P	A discrete cell cycle in the third instar eye imaginal disc after progression of the morphogenetic furrow that contributes to compound eye morphogenesis. It is essential for generation of a sufficient pool of uncommitted cells to develop complete ommatidia.
16331	morphogenesis of embryonic epithelium	P	The process in which the anatomical structures of embryonic epithelia are generated and organized.
16332	establishment or maintenance of polarity of embryonic epithelium	P	Any cellular process that results in the specification, formation or maintenance of anisotropic intracellular organization of epithelial cells in an embryo.
16333	morphogenesis of follicular epithelium	P	The process in which the anatomical structures of a follicular epithelium are generated and organized.
16334	establishment or maintenance of polarity of follicular epithelium	P	Any cellular process that results in the specification, formation or maintenance of a polarized follicular epithelial sheet.
16335	morphogenesis of larval imaginal disc epithelium	P	The process in which the anatomical structures of a larval imaginal disc epithelium are generated and organized.
16336	establishment or maintenance of polarity of larval imaginal disc epithelium	P	Any cellular process that results in the specification, formation or maintenance of a polarized larval imaginal disc epithelium.
16337	single organismal cell-cell adhesion	P	The attachment of one cell to another cell via adhesion molecules, where both cells are part of the same organism.
16338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules	P	The attachment of one cell to another cell via adhesion molecules that do not require the presence of calcium for the interaction.
16339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules	P	The attachment of one cell to another cell via adhesion molecules that require the presence of calcium for the interaction.
16340	calcium-dependent cell-matrix adhesion	P	The binding of a cell to the extracellular matrix via adhesion molecules that require the presence of calcium for the interaction.
16342	catenin complex	C	Complex of peripheral cytoplasmic proteins (alpha-, beta- and gamma-catenin) that interact with the cytoplasmic region of uvomorulin/E-cadherin to connect it to the actin cytoskeleton.
16344	meiotic chromosome movement towards spindle pole	P	The cell cycle process in which the directed movement of chromosomes from the center of the spindle towards the spindle poles takes place, mediated by the shortening of microtubules attached to the chromosomes. This occurs during meiosis.
16345	female meiotic chromosome movement towards spindle pole	P	The directed movement of chromosomes in the center of the spindle towards the spindle poles, mediated by the shortening of microtubules attached to the chromosomes, during female meiosis.
16346	male meiotic chromosome movement towards spindle pole	P	The directed movement of chromosomes in the center of the spindle towards the spindle poles, mediated by the shortening of microtubules attached to the chromosomes, during male meiosis.
16348	imaginal disc-derived leg joint morphogenesis	P	The process in which the anatomical structures of an imaginal disc-derived leg joint are generated and organized. The leg joint is a flexible region that separates the rigid sections of a leg to allow movement in a controlled manner. An example of this is found in Drosophila melanogaster.
16358	dendrite development	P	The process whose specific outcome is the progression of the dendrite over time, from its formation to the mature structure. A dendrite is a freely branching protoplasmic process of a nerve cell.
16360	sensory organ precursor cell fate determination	P	The process in which a cell becomes capable of differentiating autonomously into a sensory organ precursor cell regardless of its environment; upon determination, the cell fate cannot be reversed.
16361	activin receptor activity, type I	F	Combining with activin-bound type II activin receptor to initiate a change in cell activity; upon binding, acts as a downstream transducer of activin signals.
16362	activin receptor activity, type II	F	Combining with activin to initiate a change in cell activity; upon ligand binding, binds to and catalyses the phosphorylation of a type I activin receptor.
16363	nuclear matrix	C	The dense fibrillar network lying on the inner side of the nuclear membrane.
16401	palmitoyl-CoA oxidase activity	F	Catalysis of the reaction: palmitoyl-CoA + O2 = trans-2,3-dehydropalmitoyl-CoA + hydrogen peroxide.
16402	pristanoyl-CoA oxidase activity	F	Catalysis of the reaction: pristanoyl-CoA + O2 = trans-2,3-dehydropristanoyl-CoA + hydrogen peroxide.
16403	dimethylargininase activity	F	Catalysis of the reaction: N(G),N(G)-dimethyl-L-arginine + H2O = dimethylamine + L-citrulline.
16404	15-hydroxyprostaglandin dehydrogenase (NAD+) activity	F	Catalysis of the reaction: (5Z,13E)-(15S)-11-alpha,15-dihydroxy-9-oxoprost-13-enoate + NAD+ = (5Z,13E)-11-alpha-hydroxy-9,15-dioxoprost-13-enoate + NADH + H+.
16405	CoA-ligase activity	F	Catalysis of the reaction: substrate + ATP + CoASH = AMP + diphosphate + substrate-CoA.
16406	carnitine O-acyltransferase activity	F	Catalysis of the transfer of an acyl group to an oxygen atom on the carnitine molecule.
16407	acetyltransferase activity	F	Catalysis of the transfer of an acetyl group to an acceptor molecule.
16408	C-acyltransferase activity	F	Catalysis of the transfer of an acyl group to a carbon atom on the acceptor molecule.
16409	palmitoyltransferase activity	F	Catalysis of the transfer of a palmitoyl (CH3-[CH2]14-CO-) group to an acceptor molecule.
16410	N-acyltransferase activity	F	Catalysis of the transfer of an acyl group to a nitrogen atom on the acceptor molecule.
16411	acylglycerol O-acyltransferase activity	F	Catalysis of the transfer of an acyl group to an oxygen atom on the acylglycerol molecule.
16412	serine O-acyltransferase activity	F	Catalysis of the transfer of an acyl group to an oxygen atom on the serine molecule.
16413	O-acetyltransferase activity	F	Catalysis of the transfer of an acetyl group to an oxygen atom on the acceptor molecule.
16414	O-octanoyltransferase activity	F	Catalysis of the transfer of an octanoyl group to an oxygen atom on the acceptor molecule.
16415	octanoyltransferase activity	F	Catalysis of the transfer of an octanoyl (CH3-[CH2]6-CO-) group to an acceptor molecule.
16416	O-palmitoyltransferase activity	F	Catalysis of the transfer of a palmitoyl group to an oxygen atom on the acceptor molecule.
16417	S-acyltransferase activity	F	Catalysis of the transfer of an acyl group to a sulfur atom on the acceptor molecule.
16418	S-acetyltransferase activity	F	Catalysis of the transfer of an acetyl group to a sulfur atom on the acceptor molecule.
16419	S-malonyltransferase activity	F	Catalysis of the transfer of a malonyl group to a sulfur atom on the acceptor molecule.
16420	malonyltransferase activity	F	Catalysis of the transfer of a malonyl (HOOC-CH2-CO-) group to an acceptor molecule.
16421	CoA carboxylase activity	F	Catalysis of the joining of a carboxyl group to a molecule that is attached to CoA, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate.
16422	mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + m(7)G(5')pppAm = S-adenosyl-L-homocysteine + m(7)G(5')pppm(6)Am.
16423	tRNA (guanine) methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing methylguanine.
16426	tRNA (adenine) methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing methyladenine.
16427	tRNA (cytosine) methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing methylcytosine.
16428	tRNA (cytosine-5-)-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing 5-methylcytosine.
16429	tRNA (adenine-N1-)-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing N1-methyladenine.
16430	tRNA (adenine-N6-)-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing N6-methyladenine.
16432	tRNA-uridine aminocarboxypropyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + tRNA uridine = 5'-methylthioadenosine + tRNA 3-(3-amino-3-carboxypropyl)-uridine.
16433	rRNA (adenine) methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing methyladenine.
16434	rRNA (cytosine) methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing methylcytosine.
16435	rRNA (guanine) methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing methylguanine.
16436	rRNA (uridine) methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing methyluridine.
16437	tRNA cytidylyltransferase activity	F	Catalysis of the reaction: CTP + tRNA(n) = diphosphate + tRNA(n+1).
16438	tRNA-queuosine beta-mannosyltransferase activity	F	Catalysis of the reaction: GDP-mannose + tRNA(Asp)-queuosine = GDP + tRNA(Asp)-O-5''-beta-D-mannosylqueuosine.
16441	posttranscriptional gene silencing	P	The inactivation of gene expression by a posttranscriptional mechanism.
16442	RISC complex	C	A ribonucleoprotein complex that contains members of the Argonaute family of proteins, small interfering RNAs (siRNAs) or microRNAs (miRNAs), and miRNA or siRNA-complementary mRNAs, in addition to a number of accessory factors. The RISC complex is involved in posttranscriptional repression of gene expression through downregulation of translation or induction of mRNA degradation.
16443	bidentate ribonuclease III activity	F	Catalysis of the digestion of double-stranded RNAs into 20 to 30-nucleotide products. These products typically associate to the RNA-induced silencing complex and serve as guide RNAs for posttranslational RNA interference.
16444	somatic cell DNA recombination	P	Recombination occurring within or between DNA molecules in somatic cells.
16445	somatic diversification of immunoglobulins	P	The somatic process that results in the generation of sequence diversity of immunoglobulins.
16446	somatic hypermutation of immunoglobulin genes	P	Mutations occurring somatically that result in amino acid changes in the rearranged V regions of immunoglobulins.
16447	somatic recombination of immunoglobulin gene segments	P	The process in which immunoglobulin genes are formed through recombination of the germline genetic elements, as known as immunoglobulin gene segments, within a single locus.
16453	C-acetyltransferase activity	F	Catalysis of the transfer of an acetyl group to a carbon atom on the acceptor molecule.
16454	C-palmitoyltransferase activity	F	Catalysis of the transfer of a palmitoyl group to a carbon atom on the acceptor molecule.
16456	X chromosome located dosage compensation complex, transcription activating	C	An RNA-protein complex localized to the X chromosome of males where it is required for the hyper-transcriptional activation of the X chromosome. An example of this is found in Drosophila melanogaster.
16457	dosage compensation complex assembly involved in dosage compensation by hyperactivation of X chromosome	P	The aggregation, arrangement and bonding together of proteins on DNA to form the complex that mediates dosage compensation on the X chromosome of the heterogametic sex, ultimately resulting in a two-fold increase in transcription from this chromosome. An example of this is found in Drosophila melanogaster.
16458	gene silencing	P	Any process carried out at the cellular level that results in either long-term transcriptional repression via action on chromatin structure or RNA mediated, post-transcriptional repression of gene expression.
16459	myosin complex	C	A protein complex, formed of one or more myosin heavy chains plus associated light chains and other proteins, that functions as a molecular motor; uses the energy of ATP hydrolysis to move actin filaments or to move vesicles or other cargo on fixed actin filaments; has magnesium-ATPase activity and binds actin. Myosin classes are distinguished based on sequence features of the motor, or head, domain, but also have distinct tail regions that are believed to bind specific cargoes.
16460	myosin II complex	C	A myosin complex containing two class II myosin heavy chains, two myosin essential light chains and two myosin regulatory light chains. Also known as classical myosin or conventional myosin, the myosin II class includes the major muscle myosin of vertebrate and invertebrate muscle, and is characterized by alpha-helical coiled coil tails that self assemble to form a variety of filament structures.
16461	unconventional myosin complex	C	A portmanteau term for myosins other than myosin II.
16462	pyrophosphatase activity	F	Catalysis of the hydrolysis of a pyrophosphate bond between two phosphate groups, leaving one phosphate on each of the two fragments.
16463	zinc-exporting ATPase activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Zn2+(in) -> ADP + phosphate + Zn2+(out).
16464	chloroplast protein-transporting ATPase activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O = ADP + phosphate; drives the transport of proteins into the chloroplast stroma.
16465	chaperonin ATPase complex	C	Multisubunit protein complex with 2x7 (Type I, in most cells) or 2x8 (Type II, in Archaea) ATP-binding sites involved in maintaining an unfolded polypeptide structure before folding or to entry into mitochondria and chloroplasts.
16469	proton-transporting two-sector ATPase complex	C	A large protein complex that catalyzes the synthesis or hydrolysis of ATP by a rotational mechanism, coupled to the transport of protons across a membrane. The complex comprises a membrane sector (F0, V0, or A0) that carries out proton transport and a cytoplasmic compartment sector (F1, V1, or A1) that catalyzes ATP synthesis or hydrolysis. Two major types have been characterized: V-type ATPases couple ATP hydrolysis to the transport of protons across a concentration gradient, whereas F-type ATPases, also known as ATP synthases, normally run in the reverse direction to utilize energy from a proton concentration or electrochemical gradient to synthesize ATP. A third type, A-type ATPases have been found in archaea, and are closely related to eukaryotic V-type ATPases but are reversible.
16471	vacuolar proton-transporting V-type ATPase complex	C	A proton-transporting two-sector ATPase complex found in the vacuolar membrane, where it acts as a proton pump to mediate acidification of the vacuolar lumen.
16472	sodium ion-transporting two-sector ATPase complex	C	A large protein complex that catalyzes the synthesis or hydrolysis of ATP by a rotational mechanism, coupled to the transport of sodium ions across a membrane. The complex comprises a membrane sector (F0 or V0) that carries out ion transport and a cytoplasmic compartment sector (F1 or V1) that catalyzes ATP synthesis or hydrolysis.
16473	sodium ion-transporting F-type ATPase complex	C	A sodium ion-transporting two-sector ATPase complex that catalyzes the phosphorylation of ADP to ATP. The complex comprises a membrane sector (F0) that carries out proton transport and a cytoplasmic compartment sector (F1) that catalyzes ATP synthesis by a rotational mechanism.
16474	sodium ion-transporting V-type ATPase complex	C	A sodium ion-transporting two-sector ATPase complex that couples ATP hydrolysis to the transport of sodium ions across a concentration gradient. The complex comprises a membrane sector (V0) that carries out proton transport and a cytoplasmic compartment sector (V1) that catalyzes ATP hydrolysis.
16475	detection of nuclear:cytoplasmic ratio	P	The process in which the size of the nucleus with respect to its cytoplasm is sensed by a cell.
16476	regulation of embryonic cell shape	P	Any process that modulates the surface configuration of an embryonic cell.
16477	cell migration	P	The controlled self-propelled movement of a cell from one site to a destination guided by molecular cues. Cell migration is a central process in the development and maintenance of multicellular organisms.
16479	negative regulation of transcription from RNA polymerase I promoter	P	Any process that stops, prevents, or reduces the frequency, rate or extent of transcription from an RNA polymerase I promoter.
16480	negative regulation of transcription from RNA polymerase III promoter	P	Any process that stops, prevents, or reduces the frequency, rate or extent of transcription from an RNA polymerase III promoter.
16482	cytosolic transport	P	The directed movement of substances or organelles within the cytosol.
16483	tryptophan hydroxylase activator activity	F	Increases the activity of the enzyme tryptophase hydroxylase.
16485	protein processing	P	Any protein maturation process achieved by the cleavage of a peptide bond or bonds within a protein. Protein maturation is the process leading to the attainment of the full functional capacity of a protein.
16486	peptide hormone processing	P	The generation of a mature peptide hormone by posttranslational processing of a prohormone.
16487	farnesol metabolic process	P	The chemical reactions and pathways involving the sesquiterpenoid alcohol farnesol, 3,7,11-trimethyl-2,6,10,dodecatrien-1-ol.
16488	farnesol catabolic process	P	The chemical reactions and pathways resulting in the breakdown of the sesquiterpenoid alcohol farnesol, 3,7,11-trimethyl-2,6,10,dodecatrien-1-ol.
16490	structural constituent of peritrophic membrane	F	The action of a molecule that contributes to the structural integrity of the peritrophic membrane, a tubular sheath of cuticle that shields the epithelial cells of the midgut from the gut contents. An example of this is found in Drosophila melanogaster.
16491	oxidoreductase activity	F	Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.
16492	G-protein coupled neurotensin receptor activity	F	Combining with the tridecapeptide neurotensin to initiate a G-protein mediated change in cell activity. A G-protein is a signal transduction molecule that alternates between an inactive GDP-bound and an active GTP-bound state.
16493	C-C chemokine receptor activity	F	Combining with a C-C chemokine and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. C-C chemokines do not have an amino acid between the first two cysteines of the characteristic four-cysteine motif.
16494	C-X-C chemokine receptor activity	F	Combining with a C-X-C chemokine and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. A C-X-C chemokine has a single amino acid between the first two cysteines of the characteristic four cysteine motif.
16495	C-X3-C chemokine receptor activity	F	Combining with a C-X3-C chemokine and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. A C-X3-C chemokine has three amino acids between the first two cysteines of the characteristic four-cysteine motif.
16496	substance P receptor activity	F	Combining with substance P, the peptide Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met, to initiate a change in cell activity.
16497	substance K receptor activity	F	Combining with substance K, the peptide His-Lys-Thr-Asp-Ser-Phe-Val-Gly-Leu-Met, to initiate a change in cell activity.
16498	neuromedin K receptor activity	F	Combining with neuromedin K, the peptide Asp-Met-His-Asp-Phe-Phe-Val-Gly-Leu-Met to initiate a change in cell activity.
16499	orexin receptor activity	F	Combining with orexin to initiate a change in cell activity.
16500	protein-hormone receptor activity	F	Combining with a protein hormone to initiate a change in cell activity.
16501	prostacyclin receptor activity	F	Combining with prostacyclin (PGI(2)) to initiate a change in cell activity.
16502	nucleotide receptor activity	F	Combining with a nucleotide and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. A nucleotide is a compound that consists of a nucleoside esterified with a phosphate molecule.
16503	pheromone receptor activity	F	Combining with a pheromone to initiate a change in cell activity. A pheromone is a substance used in olfactory communication between organisms of the same species eliciting a change in sexual or social behavior.
16504	peptidase activator activity	F	Binds to and increases the activity of a peptidase, any enzyme that catalyzes the hydrolysis peptide bonds.
16505	peptidase activator activity involved in apoptotic process	F	Increases the activity of a peptidase that is involved in the apoptotic process.
16507	mitochondrial fatty acid beta-oxidation multienzyme complex	C	A complex that includes the long-chain 3-hydroxyacyl-CoA dehydrogenase and long-chain enoyl-CoA hydratase activities in two subunits (alpha and beta), catalyzing two steps of the fatty acid beta-oxidation cycle within the mitochondrial matrix.
16508	long-chain-enoyl-CoA hydratase activity	F	Catalysis of the reaction: a long-chain (3S)-3-hydroxyacyl-CoA = a long-chain trans-2-enoyl-CoA + H2O. A long-chain acyl-CoA is an acyl-CoA thioester where the acyl chain contains 13 to 22 carbon atoms.
16509	long-chain-3-hydroxyacyl-CoA dehydrogenase activity	F	Catalysis of the reaction: (S)-3-hydroxyacyl-CoA + NAD(P)+ = 3-oxoacyl-CoA + NAD(P)H + H+, where the acyl group is a long-chain fatty acid residue. A long-chain fatty acid is a fatty acid with a chain length between C13 and C22.
16513	core-binding factor complex	C	A heterodimeric transcription factor complex that contains an alpha subunit (Runx1, Runx2 or Runx3 in human) that binds DNA and a non-DNA-binding beta subunit (CBFbeta), and binds to a consensus sequence 5'-YGYGGTY-3' found in several enhancers and promoters; the beta subunit enhances the DNA binding of the alpha subunit.
16514	SWI/SNF complex	C	A SWI/SNF-type complex that contains nine or more proteins, including both conserved (core) and nonconserved components; the Swi2/Snf2 ATPase is one of the core components.
16515	interleukin-13 receptor activity	F	Combining with interleukin-13 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
16516	interleukin-4 receptor complex	C	A protein complex that binds interleukin-4 (IL-4) and consists of an alpha chain that binds IL-4 with high affinity and a gamma common chain that also forms part of the interleukin-2 receptor.
16517	interleukin-12 receptor activity	F	Combining with interleukin-12 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
16518	interleukin-14 receptor activity	F	Combining with interleukin-14 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
16519	gastric inhibitory peptide receptor activity	F	Combining with gastric inhibitory peptide (GIP) and transmitting the signal across the membrane to activate an associated G-protein.
16520	growth hormone-releasing hormone receptor activity	F	Combining with growth hormone-releasing hormone to initiate a change in cell activity.
16521	pituitary adenylate cyclase activating polypeptide activity	F	The action characteristic of pituitary adenylate cyclase activating polypeptide, a peptide produced in the hypothalamus that binds to receptors to exert pleiotropic effects including control of neurotransmitter release, vasodilation, bronchodilation, activation of intestinal motility, increase in insulin and histamine secretion, immune modulation, and stimulation of cell proliferation and differentiation.
16524	latrotoxin receptor activity	F	Combining with alpha-latrotoxin, a potent presynaptic neurotoxin, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
16525	negative regulation of angiogenesis	P	Any process that stops, prevents, or reduces the frequency, rate or extent of angiogenesis.
16528	sarcoplasm	C	The cytoplasm of a muscle cell; includes the sarcoplasmic reticulum.
16529	sarcoplasmic reticulum	C	A fine reticular network of membrane-limited elements that pervades the sarcoplasm of a muscle cell; continuous over large portions of the cell and with the nuclear envelope; that part of the endoplasmic reticulum specialized for calcium release, uptake and storage.
16530	metallochaperone activity	F	Assists in the delivery of metal ions to target proteins or compartments.
16531	copper chaperone activity	F	Assists in the delivery of copper ions to target proteins or compartments.
16532	superoxide dismutase copper chaperone activity	F	A copper chaperone activity that specifically delivers copper to the Cu-Zn superoxide dismutase, to activate superoxide dismutase activity.
16533	cyclin-dependent protein kinase 5 holoenzyme complex	C	A protein complex that activates cyclin-dependent kinase 5; composed of regulatory and catalytic subunits.
16534	cyclin-dependent protein kinase 5 activator activity	F	Binds to and increases the activity of cyclin-dependent protein kinase 5.
16538	cyclin-dependent protein serine/threonine kinase regulator activity	F	Modulates the activity of a cyclin-dependent protein serine/threonine kinase, enzymes of the protein kinase family that are regulated through association with cyclins and other proteins.
16539	intein-mediated protein splicing	P	The removal of an internal amino acid sequence (an intein) from a protein during protein maturation; the excision of inteins is precise and the N- and C-terminal exteins are joined by a normal peptide bond. Protein splicing involves 4 nucleophilic displacements by the 3 conserved splice junction residues.
16540	protein autoprocessing	P	Processing which a protein carries out itself. This involves actions such as the autolytic removal of residues to generate the mature form of the protein.
16543	male courtship behavior, orientation prior to leg tapping and wing vibration	P	The process during courtship, where the male orients towards a potential partner. An example of this is found in Drosophila melanogaster.
16544	male courtship behavior, tapping to detect pheromone	P	The process during courtship where the male insect taps the female with his frontal leg. An example of this is found in Drosophila melanogaster.
16545	male courtship behavior, veined wing vibration	P	The process during courtship where the male insect vibrates his wings. An example of this is found in Drosophila melanogaster.
16546	male courtship behavior, proboscis-mediated licking	P	The process during courtship where the male fly licks the genitalia of a stationary female fly with his proboscis. An example of this is found in Drosophila melanogaster.
16553	base conversion or substitution editing	P	Any base modification or substitution events that result in alterations in the coding potential or structural properties of RNAs as a result of changes in the base-pairing properties of the modified ribonucleoside(s).
16554	cytidine to uridine editing	P	The conversion of a cytosine residue to uridine in an RNA molecule by deamination.
16555	uridine to cytidine editing	P	The conversion of a uridine residue to cytosine in an RNA molecule by amination.
16556	mRNA modification	P	The covalent alteration of one or more nucleotides within an mRNA molecule to produce an mRNA molecule with a sequence that differs from that coded genetically.
16557	peroxisome membrane biogenesis	P	The process in which a peroxisome membrane is synthesized, aggregates, and bonds together.
16558	protein import into peroxisome matrix	P	The import of proteins into the peroxisomal matrix. A peroxisome targeting signal (PTS) binds to a soluble receptor protein in the cytosol, and the resulting complex then binds to a receptor protein in the peroxisome membrane and is imported. The cargo protein is then released into the peroxisome matrix.
16559	peroxisome fission	P	The division of a mature peroxisome within a cell to form two or more separate peroxisome compartments.
16560	protein import into peroxisome matrix, docking	P	The process in which a complex formed of a peroxisome targeting sequence (PTS) receptor bound to a PTS-bearing protein docks with translocation machinery in the peroxisomal membrane.
16561	protein import into peroxisome matrix, translocation	P	The process in which proteins are moved across the peroxisomal membrane into the matrix. It is likely that the peroxisome targeting sequence receptor remains associated with cargo proteins during translocation.
16562	protein import into peroxisome matrix, receptor recycling	P	The process in which peroxisome targeting sequence receptors dissociates from cargo proteins and are returned to the cytosol.
16567	protein ubiquitination	P	The process in which one or more ubiquitin groups are added to a protein.
16569	covalent chromatin modification	P	The alteration of DNA or protein in chromatin by the covalent addition or removal of chemical groups.
16570	histone modification	P	The covalent alteration of one or more amino acid residues within a histone protein.
16571	histone methylation	P	The modification of histones by addition of methyl groups.
16572	histone phosphorylation	P	The modification of histones by addition of phosphate groups.
16573	histone acetylation	P	The modification of a histone by the addition of an acetyl group.
16574	histone ubiquitination	P	The modification of histones by addition of ubiquitin groups.
16575	histone deacetylation	P	The modification of histones by removal of acetyl groups.
16576	histone dephosphorylation	P	The modification of histones by removal of phosphate groups.
16577	histone demethylation	P	The modification of histones by removal of methyl groups.
16578	histone deubiquitination	P	The modification of histones by removal of ubiquitin groups.
16579	protein deubiquitination	P	The removal of one or more ubiquitin groups from a protein.
16580	Sin3 complex	C	A multiprotein complex that functions broadly in eukaryotic organisms as a transcriptional repressor of protein-coding genes, through the gene-specific deacetylation of histones. Amongst its subunits, the Sin3 complex contains Sin3-like proteins, and a number of core proteins that are shared with the NuRD complex (including histone deacetylases and histone binding proteins). The Sin3 complex does not directly bind DNA itself, but is targeted to specific genes through protein-protein interactions with DNA-binding proteins.
16581	NuRD complex	C	An approximately 2 MDa multi-subunit complex that exhibits ATP-dependent chromatin remodeling activity in addition to histone deacetylase (HDAC) activity, and has been shown to establish transcriptional repression of a number of target genes in vertebrates, invertebrates and fungi. Amongst its subunits, the NuRD complex contains histone deacetylases, histone binding proteins and Mi-2-like proteins.
16584	nucleosome positioning	P	Ordering of successions of nucleosomes into regular arrays so that nucleosomes are positioned at defined distances from one another.
16586	RSC complex	C	A protein complex similar to, but more abundant than, the Swi/Snf complex. The RSC complex is generally recruited to RNA polymerase III promoters and is specifically recruited to RNA polymerase II promoters by transcriptional activators and repressors; it is also involved in non-homologous end joining.
16587	Isw1 complex	C	A protein complex that contains an Isw1 subunit from the ISWI-family of ATPases and acts to modify chromatin structure.
16589	NURF complex	C	An ISWI complex that contains an ATPase subunit of the ISWI family (SNF2L in mammals), a NURF301 homolog (BPTF in humans), and additional subunits, though the composition of these additional subunits varies slightly with species. NURF is involved in regulation of transcription from TRNA polymerase II promoters.
16590	ACF complex	C	An ISWI complex that contains an ATPase subunit of the ISWI family (SNF2H in mammals, Isw2 in S. cerevisiae), an ACF1 homolog, and generally no other subunits, though Xenopus is an exception with a third non-conserved subunit. ACF plays roles in regulation of RNA polymerase II transcription and in DNA replication and repair.
16591	DNA-directed RNA polymerase II, holoenzyme	C	A nuclear DNA-directed RNA polymerase complex containing an RNA polymerase II core enzyme as well as additional proteins and transcription factor complexes, that are capable of promoter recognition and transcription initiation from an RNA polymerase II promoter in vivo. These additional components may include general transcription factor complexes TFIIA, TFIID, TFIIE, TFIIF, or TFIIH, as well as Mediator, SWI/SNF, GCN5, or SRBs and confer the ability to recognize promoters.
16592	mediator complex	C	A protein complex that interacts with the carboxy-terminal domain of the largest subunit of RNA polymerase II and plays an active role in transducing the signal from a transcription factor to the transcriptional machinery. The mediator complex is required for activation of transcription of most protein-coding genes, but can also act as a transcriptional corepressor. The Saccharomyces complex contains several identifiable subcomplexes: a head domain comprising Srb2, -4, and -5, Med6, -8, and -11, and Rox3 proteins; a middle domain comprising Med1, -4, and -7, Nut1 and -2, Cse2, Rgr1, Soh1, and Srb7 proteins; a tail consisting of Gal11p, Med2p, Pgd1p, and Sin4p; and a regulatory subcomplex comprising Ssn2, -3, and -8, and Srb8 proteins. Metazoan mediator complexes have similar modular structures and include homologs of yeast Srb and Med proteins.
16593	Cdc73/Paf1 complex	C	A multiprotein complex that associates with RNA polymerase II and general RNA polymerase II transcription factor complexes and may be involved in both transcriptional initiation and elongation. In Saccharomyces the complex contains Paf1p, Cdc73p, Ctr9p, Rtf1p, and Leo1p.
16594	glycine binding	F	Interacting selectively and non-covalently with glycine, aminoethanoic acid.
16595	glutamate binding	F	Interacting selectively and non-covalently with glutamate, the anion of 2-aminopentanedioic acid.
16596	thienylcyclohexylpiperidine binding	F	Interacting selectively and non-covalently with thienylcyclohexylpiperidine.
16597	amino acid binding	F	Interacting selectively and non-covalently with an amino acid, organic acids containing one or more amino substituents.
16598	protein arginylation	P	The conjugation of arginine to the N-terminal aspartate or glutamate of a protein; required for the degradation of the protein via the ubiquitin pathway.
16600	flotillin complex	C	A protein complex that contains flotillin-1 and flotillin-2, and may contain associated proteins. Flotillins associate into membrane microdomains resembling caveolae.
16601	Rac protein signal transduction	P	A series of molecular signals within the cell that are mediated by a member of the Rac family of proteins switching to a GTP-bound active state.
16602	CCAAT-binding factor complex	C	A heteromeric transcription factor complex that binds to the CCAAT-box upstream of promoters; functions as both an activator and a repressor, depending on its interacting cofactors. Typically trimeric consisting of NFYA, NFYB and NFYC subunits. In Saccharomyces, it activates the transcription of genes in response to growth in a nonfermentable carbon source and consists of four known subunits: HAP2, HAP3, HAP4 and HAP5.
16603	glutaminyl-peptide cyclotransferase activity	F	Catalysis of the reaction: L-glutaminyl-peptide = 5-oxoprolyl-peptide + NH3.
16604	nuclear body	C	Extra-nucleolar nuclear domains usually visualized by confocal microscopy and fluorescent antibodies to specific proteins.
16605	PML body	C	A class of nuclear body; they react against SP100 auto-antibodies (PML, promyelocytic leukemia); cells typically contain 10-30 PML bodies per nucleus; alterations in the localization of PML bodies occurs after viral infection.
16606	LYSP100-associated nuclear domain	C	A nuclear body that is enriched in the lymphoid cell-specific protein LYSp100B; LANDs are globular, electron-dense structures and are morphologically distinct from the annular structures characteristic of PML bodies.
16607	nuclear speck	C	A discrete extra-nucleolar subnuclear domain, 20-50 in number, in which splicing factors are seen to be localized by immunofluorescence microscopy.
16608	growth hormone-releasing hormone activity	F	The action characteristic of growth hormone-releasing hormone, any of a family of peptide hormones that act on the anterior pituitary to stimulate the secretion of growth hormone and exert a trophic effect on the gland.
16610	nitrogenase complex	C	An enzyme complex composed of two proteins, dinitrogenase and nitrogenase reductase; dinitrogenase is tetrameric with an alpha2-beta2 structure and nitrogenase reductase is a homodimer, and both are associated with metal ions, which differ between species. Both proteins are required for the enzyme activity of the complex, the formation of oxidized ferredoxin and ammonia from reduced ferredoxin and nitrogen.
16611	iron-iron nitrogenase complex	C	An enzyme complex containing an iron-iron cluster found in species such as the photosynthetic bacterium Rhodobacter capsulatus. It is composed of two main subunits, dinitrogenase and nitrogenase reductase. Dinitrogenase, the iron-iron containing subunit, has an alpha1-beta2 or alpha2-beta2 structure, and the nitrogenase reductase subunit is a homodimer. Functions in the catalysis of the formation of oxidized ferredoxin and ammonia from reduced ferredoxin and nitrogen.
16612	molybdenum-iron nitrogenase complex	C	An enzyme complex containing a molybdenum-iron cluster found in many species. It is composed of two proteins, dinitrogenase and nitrogenase reductase; dinitrogenase, the molybdenum-iron protein, is tetrameric with an alpha2-beta2 structure, and nitrogenase reductase is a homodimer.
16613	vanadium-iron nitrogenase complex	C	An enzyme complex containing a vanadium-iron cluster found in some species, such as Azotobacter vinelandii. It is composed of two proteins, dinitrogenase and nitrogenase reductase; dinitrogenase, the vanadium-iron protein, is tetrameric with an alpha2-beta2 structure, and nitrogenase reductase is a homodimer.
16614	oxidoreductase activity, acting on CH-OH group of donors	F	Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group act as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.
16615	malate dehydrogenase activity	F	Catalysis of the reversible conversion of pyruvate or oxaloacetate to malate.
16616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	F	Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces NAD+ or NADP.
16617	4-oxoproline reductase activity	F	Catalysis of the reaction: 4-hydroxy-L-proline + NAD+ = 4-oxoproline + NADH + H+.
16618	hydroxypyruvate reductase activity	F	Catalysis of the reaction: D-glycerate + NADP+ = hydroxypyruvate + NADPH + H+.
16620	oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	F	Catalysis of an oxidation-reduction (redox) reaction in which an aldehyde or ketone (oxo) group acts as a hydrogen or electron donor and reduces NAD or NADP.
16621	cinnamoyl-CoA reductase activity	F	Catalysis of the reaction: cinnamaldehyde + CoA + NADP+ = cinnamoyl-CoA + NADPH + H+.
16622	oxidoreductase activity, acting on the aldehyde or oxo group of donors, cytochrome as acceptor	F	Catalysis of an oxidation-reduction (redox) reaction in which an aldehyde or ketone (oxo) group acts as a hydrogen or electron donor and reduces a cytochrome.
16623	oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor	F	Catalysis of an oxidation-reduction (redox) reaction in which an aldehyde or ketone (oxo) group acts as a hydrogen or electron donor and reduces oxygen.
16624	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor	F	Catalysis of an oxidation-reduction (redox) reaction in which an aldehyde or ketone (oxo) group acts as a hydrogen or electron donor and reduces a disulfide.
16625	oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor	F	Catalysis of an oxidation-reduction (redox) reaction in which an aldehyde or ketone (oxo) group acts as a hydrogen or electron donor and reduces an iron-sulfur protein.
16627	oxidoreductase activity, acting on the CH-CH group of donors	F	Catalysis of an oxidation-reduction (redox) reaction in which a CH-CH group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.
16628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor	F	Catalysis of an oxidation-reduction (redox) reaction in which a CH-CH group acts as a hydrogen or electron donor and reduces NAD or NADP.
16629	12-oxophytodienoate reductase activity	F	Catalysis of the reaction: 8-[(1R,2R)-3-oxo-2-{(Z)-pent-2-en-1-yl}cyclopentyl]octanoate + NADP(+) = (15Z)-12-oxophyto-10,15-dienoate + H(+) + NADPH.
16630	protochlorophyllide reductase activity	F	Catalysis of the reaction: chlorophyllide a + NADP+ = protochlorophyllide + NADPH + H+.
16631	enoyl-[acyl-carrier-protein] reductase activity	F	Catalysis of the reaction: acyl-[acyl-carrier protein] + NAD(P)+ = trans-2,3-dehydroacyl-[acyl-carrier protein] + NAD(P)H + H+.
16632	oxidoreductase activity, acting on the CH-CH group of donors, cytochrome as acceptor	F	Catalysis of an oxidation-reduction (redox) reaction in which a CH-CH group acts as a hydrogen or electron donor and reduces a cytochrome.
16633	galactonolactone dehydrogenase activity	F	Catalysis of the reaction: L-galactono-1,4-lactone + 2 ferricytochrome c = L-ascorbate + 2 ferrocytochrome c.
16634	oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor	F	Catalysis of an oxidation-reduction (redox) reaction in which a CH-CH group acts as a hydrogen or electron donor and reduces oxygen.
16635	oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor	F	Catalysis of an oxidation-reduction (redox) reaction in which a CH-CH group acts as a hydrogen or electron donor and reduces a quinone or related compound.
16636	oxidoreductase activity, acting on the CH-CH group of donors, iron-sulfur protein as acceptor	F	Catalysis of an oxidation-reduction (redox) reaction in which a CH-CH group acts as a hydrogen or electron donor and reduces an iron-sulfur protein.
16638	oxidoreductase activity, acting on the CH-NH2 group of donors	F	Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH2 group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.
16639	oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor	F	Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH2 group acts as a hydrogen or electron donor and reduces NAD+ or NADP.
16640	oxidoreductase activity, acting on the CH-NH2 group of donors, cytochrome as acceptor	F	Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH2 group acts as a hydrogen or electron donor and reduces a cytochrome molecule.
16641	oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor	F	Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH2 group acts as a hydrogen or electron donor and reduces an oxygen molecule.
16642	oxidoreductase activity, acting on the CH-NH2 group of donors, disulfide as acceptor	F	Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH2 group acts as a hydrogen or electron donor and reduces a disulfide group.
16643	oxidoreductase activity, acting on the CH-NH2 group of donors, iron-sulfur protein as acceptor	F	Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH2 group acts as a hydrogen or electron donor and reduces an iron-sulfur protein.
16645	oxidoreductase activity, acting on the CH-NH group of donors	F	Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.
16646	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor	F	Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH group acts as a hydrogen or electron donor and reduces NAD or NADP.
16647	oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor	F	Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH group acts as a hydrogen or electron donor and reduces oxygen.
16648	oxidoreductase activity, acting on the CH-NH group of donors, disulfide as acceptor	F	Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH group acts as a hydrogen or electron donor and reduces disulfide.
16649	oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor	F	Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH group acts as a hydrogen or electron donor and reduces quinone or similar compound.
16651	oxidoreductase activity, acting on NAD(P)H	F	Catalysis of an oxidation-reduction (redox) reaction in which NADH or NADPH acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.
16652	oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor	F	Catalysis of an oxidation-reduction (redox) reaction in which NADH or NADPH acts as a hydrogen or electron donor and reduces NAD+ or NADP.
16653	oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor	F	Catalysis of an oxidation-reduction (redox) reaction in which NADH or NADPH acts as a hydrogen or electron donor and reduces a heme protein.
16655	oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor	F	Catalysis of an oxidation-reduction (redox) reaction in which NADH or NADPH acts as a hydrogen or electron donor and reduces a quinone or a similar acceptor molecule.
16656	monodehydroascorbate reductase (NADH) activity	F	Catalysis of the reaction: NADH + H+ + 2 monodehydroascorbate = NAD+ + 2 ascorbate.
16657	oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor	F	Catalysis of an oxidation-reduction (redox) reaction in which NADH or NADPH acts as a hydrogen or electron donor and reduces a nitrogenous group.
16661	oxidoreductase activity, acting on other nitrogenous compounds as donors	F	Catalysis of an oxidation-reduction (redox) reaction in which a nitrogenous group, excluding NH and NH2 groups, acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.
16662	oxidoreductase activity, acting on other nitrogenous compounds as donors, cytochrome as acceptor	F	Catalysis of an oxidation-reduction (redox) reaction in which a nitrogenous group, excluding NH and NH2 groups, acts as a hydrogen or electron donor and reduces a cytochrome.
16663	oxidoreductase activity, acting on other nitrogenous compounds as donors, oxygen as acceptor	F	Catalysis of an oxidation-reduction (redox) reaction in which a nitrogenous group, excluding NH and NH2 groups, acts as a hydrogen or electron donor and reduces oxygen.
16664	oxidoreductase activity, acting on other nitrogenous compounds as donors, iron-sulfur protein as acceptor	F	Catalysis of an oxidation-reduction (redox) reaction in which a nitrogenous group, excluding NH and NH2 groups, acts as a hydrogen or electron donor and reduces an iron-sulfur protein.
16667	oxidoreductase activity, acting on a sulfur group of donors	F	Catalysis of an oxidation-reduction (redox) reaction in which a sulfur-containing group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.
16668	oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor	F	Catalysis of an oxidation-reduction (redox) reaction in which a sulfur-containing group acts as a hydrogen or electron donor and reduces NAD or NADP.
16669	oxidoreductase activity, acting on a sulfur group of donors, cytochrome as acceptor	F	Catalysis of an oxidation-reduction (redox) reaction in which a sulfur-containing group acts as a hydrogen or electron donor and reduces a cytochrome.
16670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor	F	Catalysis of an oxidation-reduction (redox) reaction in which a sulfur-containing group acts as a hydrogen or electron donor and reduces oxygen.
16671	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor	F	Catalysis of an oxidation-reduction (redox) reaction in which a sulfur-containing group acts as a hydrogen or electron donor and reduces disulfide.
16672	oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor	F	Catalysis of an oxidation-reduction (redox) reaction in which a sulfur-containing group acts as a hydrogen or electron donor and reduces quinone or a related compound.
16673	oxidoreductase activity, acting on a sulfur group of donors, iron-sulfur protein as acceptor	F	Catalysis of an oxidation-reduction (redox) reaction in which a sulfur-containing group acts as a hydrogen or electron donor and reduces an iron-sulfur protein.
16675	oxidoreductase activity, acting on a heme group of donors	F	Catalysis of an oxidation-reduction (redox) reaction in which a heme group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.
16676	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor	F	Catalysis of an oxidation-reduction (redox) reaction in which a heme group acts as a hydrogen or electron donor and reduces oxygen.
16677	oxidoreductase activity, acting on a heme group of donors, nitrogenous group as acceptor	F	Catalysis of an oxidation-reduction (redox) reaction in which a heme group acts as a hydrogen or electron donor and reduces a nitrogenous group.
16679	oxidoreductase activity, acting on diphenols and related substances as donors	F	Catalysis of an oxidation-reduction (redox) reaction in which a diphenol or related substance acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.
16680	oxidoreductase activity, acting on diphenols and related substances as donors, NAD or NADP as acceptor	F	Catalysis of an oxidation-reduction (redox) reaction in which a diphenol, or related compound, acts as a hydrogen or electron donor and reduces NAD or NADP.
16681	oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor	F	Catalysis of an oxidation-reduction (redox) reaction in which a diphenol, or related compound, acts as a hydrogen or electron donor and reduces a cytochrome.
16682	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor	F	Catalysis of an oxidation-reduction (redox) reaction in which a diphenol, or related compound, acts as a hydrogen or electron donor and reduces oxygen.
16684	oxidoreductase activity, acting on peroxide as acceptor	F	Catalysis of an oxidation-reduction (redox) reaction in which the peroxide group acts as a hydrogen or electron acceptor.
16688	L-ascorbate peroxidase activity	F	Catalysis of the reaction: L-ascorbate + hydrogen peroxide = dehydroascorbate + 2 H2O.
16689	manganese peroxidase activity	F	Catalysis of the reaction: 2 Mn2+ + 2 H+ + hydrogen peroxide = 2 Mn3+ + 2 H2O.
16690	diarylpropane peroxidase activity	F	Catalysis of the reaction: (3,4-dimethoxyphenyl)methanol + H2O2 = 3,4-dimethoxybenzaldehyde + 2 H2O.
16691	chloride peroxidase activity	F	Catalysis of the reaction: 2 R-H + 2 chloride + hydrogen peroxide = 2 R-Cl + 2 H2O.
16692	NADH peroxidase activity	F	Catalysis of the reaction: H(2)O(2) + H(+) + NADH = 2 H(2)O + NAD(+).
16695	oxidoreductase activity, acting on hydrogen as donor	F	Catalysis of an oxidation-reduction (redox) reaction in which hydrogen acts as an electron donor.
16696	oxidoreductase activity, acting on hydrogen as donor, NAD or NADP as acceptor	F	Catalysis of an oxidation-reduction (redox) reaction in which hydrogen acts as an electron donor and reduces NAD or NADP.
16697	oxidoreductase activity, acting on hydrogen as donor, cytochrome as acceptor	F	Catalysis of an oxidation-reduction (redox) reaction in which hydrogen acts as an electron donor and reduces a cytochrome.
16699	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor	F	Catalysis of an oxidation-reduction (redox) reaction in which hydrogen acts as an electron donor and reduces an iron-sulfur protein.
16701	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen	F	Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from one donor, and molecular oxygen is incorporated into a donor.
16702	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	F	Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from one donor, and two oxygen atoms is incorporated into a donor.
16703	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of one atom of oxygen (internal monooxygenases or internal mixed function oxidases)	F	Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from one donor, and one oxygen atom is incorporated into a donor.
16705	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	F	Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from each of two donors, and molecular oxygen is reduced or incorporated into a donor.
16706	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors	F	Catalysis of the reaction: A + 2-oxoglutarate + O2 = B + succinate + CO2. This is an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from 2-oxoglutarate and one other donor, and one atom of oxygen is incorporated into each donor.
16707	gibberellin 3-beta-dioxygenase activity	F	Catalysis of the reaction: a gibberellin + 2-oxoglutarate + O2 = a 3-beta-hydroxy-gibberellin + succinate + CO2.
16708	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor	F	Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from NADH or NADPH and one other donor, and two atoms of oxygen are incorporated into one donor.
16709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen	F	Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from NADH or NADPH and one other donor, and one atom of oxygen is incorporated into one donor.
16710	trans-cinnamate 4-monooxygenase activity	F	Catalysis of the reaction: trans-cinnamate + NADPH + H+ + O2 = 4-hydroxycinnamate + NADP+ + H2O.
16711	flavonoid 3'-monooxygenase activity	F	Catalysis of the reaction: a flavonoid + NADPH + H+ + O2 = 3'-hydroxyflavonoid + NADP+ + H2O.
16712	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen	F	Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from reduced flavin or flavoprotein and one other donor, and one atom of oxygen is incorporated into one donor.
16713	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen	F	Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from reduced iron-sulfur protein and one other donor, and one atom of oxygen is incorporated into one donor.
16714	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen	F	Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from reduced pteridine and one other donor, and one atom of oxygen is incorporated into one donor.
16715	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen	F	Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from reduced ascorbate and one other donor, and one atom of oxygen is incorporated into one donor.
16716	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen	F	Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from each of two donors, and one atom of oxygen is incorporated into one donor.
16717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water	F	Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from each of two donors, and molecular oxygen is reduced to two molecules of water.
16719	carotene 7,8-desaturase activity	F	Catalysis of the reaction: neurosporene + donor-H2 + O2 = lycopene + acceptor + 2 H2O.
16720	delta12-fatty acid dehydrogenase activity	F	Catalysis of the reaction: AH(2) + linoleate + O(2) = A + crepenynate + 2 H(2)O.
16721	oxidoreductase activity, acting on superoxide radicals as acceptor	F	Catalysis of an oxidation-reduction (redox) reaction in which a superoxide radical (O2- or O2.-) acts as a hydrogen or electron acceptor.
16722	oxidoreductase activity, oxidizing metal ions	F	Catalysis of an oxidation-reduction in which the oxidation state of metal ion is altered.
16723	oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor	F	Catalysis of an oxidation-reduction in which the oxidation state of metal ion is altered and NAD+ or NADP+ acts as an electron acceptor.
16724	oxidoreductase activity, oxidizing metal ions, oxygen as acceptor	F	Catalysis of an oxidation-reduction in which the oxidation state of metal ion is altered and oxygen acts as an electron acceptor.
16725	oxidoreductase activity, acting on CH or CH2 groups	F	Catalysis of an oxidation-reduction (redox) reaction in which a CH2 group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.
16726	oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor	F	Catalysis of an oxidation-reduction (redox) reaction in which a CH2 group acts as a hydrogen or electron donor and reduces NAD+ or NADP.
16727	oxidoreductase activity, acting on CH or CH2 groups, oxygen as acceptor	F	Catalysis of an oxidation-reduction (redox) reaction in which a CH2 group acts as a hydrogen or electron donor and reduces an oxygen molecule.
16728	oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor	F	Catalysis of an oxidation-reduction (redox) reaction in which a CH2 group acts as a hydrogen or electron donor and reduces a disulfide group.
16730	oxidoreductase activity, acting on iron-sulfur proteins as donors	F	Catalysis of an oxidation-reduction (redox) reaction in which an iron-sulfur protein acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.
16731	oxidoreductase activity, acting on iron-sulfur proteins as donors, NAD or NADP as acceptor	F	Catalysis of an oxidation-reduction (redox) reaction in which an iron-sulfur protein acts as a hydrogen or electron donor and reduces NAD or NADP.
16732	oxidoreductase activity, acting on iron-sulfur proteins as donors, dinitrogen as acceptor	F	Catalysis of an oxidation-reduction (redox) reaction in which an iron-sulfur protein acts as a hydrogen or electron donor and reduces dinitrogen.
16737	oxidoreductase activity, acting on reduced flavodoxin as donor	F	Catalysis of an oxidation-reduction (redox) reaction in which reduced flavodoxin acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.
16738	oxidoreductase activity, acting on reduced flavodoxin as donor, dinitrogen as acceptor	F	Catalysis of an oxidation-reduction (redox) reaction in which reduced flavodoxin acts as a hydrogen or electron donor and reduces dinitrogen.
16740	transferase activity	F	Catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2.
16741	transferase activity, transferring one-carbon groups	F	Catalysis of the transfer of a one-carbon group from one compound (donor) to another (acceptor).
16742	hydroxymethyl-, formyl- and related transferase activity	F	Catalysis of the transfer of a hydroxymethyl- or formyl group from one compound (donor) to another (acceptor).
16743	carboxyl- or carbamoyltransferase activity	F	Catalysis of the transfer of a carboxyl- or carbamoyl group from one compound (donor) to another (acceptor).
16744	transferase activity, transferring aldehyde or ketonic groups	F	Catalysis of the transfer of an aldehyde or ketonic group from one compound (donor) to another (acceptor).
16746	transferase activity, transferring acyl groups	F	Catalysis of the transfer of an acyl group from one compound (donor) to another (acceptor).
16747	transferase activity, transferring acyl groups other than amino-acyl groups	F	Catalysis of the transfer of an acyl group, other than amino-acyl, from one compound (donor) to another (acceptor).
16748	succinyltransferase activity	F	Catalysis of the transfer of a succinyl (3-carboxypropanoyl) group to an acceptor molecule.
16749	N-succinyltransferase activity	F	Catalysis of the transfer of a succinyl group to a nitrogen atom on the acceptor molecule.
16750	O-succinyltransferase activity	F	Catalysis of the transfer of a succinyl group to an oxygen atom on the acceptor molecule.
16751	S-succinyltransferase activity	F	Catalysis of the transfer of a succinyl group to a sulfur atom on the acceptor molecule.
16752	sinapoyltransferase activity	F	Catalysis of the transfer of a sinapoyl group to an acceptor molecule.
16753	O-sinapoyltransferase activity	F	Catalysis of the transfer of a sinapoyl group to an oxygen atom on the acceptor molecule.
16754	sinapoylglucose-malate O-sinapoyltransferase activity	F	Catalysis of the reaction: (S)-malate + 1-O-sinapoyl-beta-D-glucose = D-glucose + sinapoyl (S)-malate.
16755	transferase activity, transferring amino-acyl groups	F	Catalysis of the transfer of an amino-acyl group from one compound (donor) to another (acceptor).
16756	glutathione gamma-glutamylcysteinyltransferase activity	F	Catalysis of the reaction: glutathione + Glu(-Cys)(n)-Gly = Gly + Glu(-Cys)(n+1)-Gly.
16757	transferase activity, transferring glycosyl groups	F	Catalysis of the transfer of a glycosyl group from one compound (donor) to another (acceptor).
16758	transferase activity, transferring hexosyl groups	F	Catalysis of the transfer of a hexosyl group from one compound (donor) to another (acceptor).
16759	cellulose synthase activity	F	Catalysis of the reaction: nucleoside-disphosphate-glucose + ((1,4)-beta-D-glucosyl)(n) = nucleoside-disphosphate + ((1,4)-beta-D-glucosyl)(n+1).
16760	cellulose synthase (UDP-forming) activity	F	Catalysis of the reaction: UDP-glucose + ((1,4)-beta-D-glucosyl)(n) = UDP + ((1,4)-beta-D-glucosyl)(n+1).
16761	cellulose synthase (GDP-forming) activity	F	Catalysis of the reaction: GDP-glucose + ((1,4)-beta-D-glucosyl)(n) = GDP + ((1,4)-beta-D-glucosyl)(n+1).
16762	xyloglucan:xyloglucosyl transferase activity	F	Catalysis of the cleavage of a beta-(1->4) bond in the backbone of a xyloglucan and transfers the xyloglucanyl segment on to O-4 of the non-reducing terminal glucose residue of an acceptor, which can be a xyloglucan or an oligosaccharide of xyloglucan.
16763	transferase activity, transferring pentosyl groups	F	Catalysis of the transfer of a pentosyl group from one compound (donor) to another (acceptor).
16765	transferase activity, transferring alkyl or aryl (other than methyl) groups	F	Catalysis of the transfer of an alkyl or aryl (but not methyl) group from one compound (donor) to another (acceptor).
16767	geranylgeranyl-diphosphate geranylgeranyltransferase activity	F	Catalysis of the reaction: 2 geranylgeranyl diphosphate = diphosphate + prephytoene diphosphate.
16768	spermine synthase activity	F	Catalysis of the reaction: S-adenosylmethioninamine + spermidine = 5'-methylthioadenosine + spermine.
16769	transferase activity, transferring nitrogenous groups	F	Catalysis of the transfer of a nitrogenous group from one compound (donor) to another (acceptor).
16770	oximinotransaminase activity	F	Catalysis of the reversible transfer of an oxime group to an acceptor.
16772	transferase activity, transferring phosphorus-containing groups	F	Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to another (acceptor).
16773	phosphotransferase activity, alcohol group as acceptor	F	Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to an alcohol group (acceptor).
16774	phosphotransferase activity, carboxyl group as acceptor	F	Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to a carboxyl group (acceptor).
16775	phosphotransferase activity, nitrogenous group as acceptor	F	Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to a nitrogenous group (acceptor).
16776	phosphotransferase activity, phosphate group as acceptor	F	Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to a phosphate group (acceptor).
16778	diphosphotransferase activity	F	Catalysis of the transfer of a diphosphate group from one compound (donor) to a another (acceptor).
16779	nucleotidyltransferase activity	F	Catalysis of the transfer of a nucleotidyl group to a reactant.
16780	phosphotransferase activity, for other substituted phosphate groups	F	Catalysis of the transfer of a substituted phosphate group, other than diphosphate or nucleotidyl residues, from one compound (donor) to a another (acceptor).
16781	phosphotransferase activity, paired acceptors	F	Catalysis of the transfer of two phosphate groups from a donor, such as ATP, to two different acceptors.
16782	transferase activity, transferring sulfur-containing groups	F	Catalysis of the transfer of a sulfur-containing group from one compound (donor) to another (acceptor).
16783	sulfurtransferase activity	F	Catalysis of the transfer of sulfur atoms from one compound (donor) to another (acceptor).
16784	3-mercaptopyruvate sulfurtransferase activity	F	Catalysis of the reaction: 3-mercaptopyruvate + cyanide = pyruvate + thiocyanate.
16785	transferase activity, transferring selenium-containing groups	F	Catalysis of the transfer of a selenium-containing group from one compound (donor) to another (acceptor).
16787	hydrolase activity	F	Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3.
16788	hydrolase activity, acting on ester bonds	F	Catalysis of the hydrolysis of any ester bond.
16790	thiolester hydrolase activity	F	Catalysis of the reaction: RCO-SR' + H2O = RCOOH + HSR'. This reaction is the hydrolysis of a thiolester bond, an ester formed from a carboxylic acid and a thiol (i.e., RCO-SR'), such as that found in acetyl-coenzyme A.
16791	phosphatase activity	F	Catalysis of the hydrolysis of phosphoric monoesters, releasing inorganic phosphate.
16793	triphosphoric monoester hydrolase activity	F	Catalysis of the hydrolysis of a triphosphoester to give a triphosphate group and a free hydroxyl group.
16794	diphosphoric monoester hydrolase activity	F	Catalysis of the hydrolysis of a diphosphoester to give a diphosphate group and a free hydroxyl group.
16795	phosphoric triester hydrolase activity	F	Catalysis of the hydrolysis of a phosphoric triester.
16796	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	F	Catalysis of the hydrolysis of ester linkages within nucleic acids by removing nucleotide residues from the 3' or 5' end to yield 5' phosphomonoesters.
16797	exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters	F	Catalysis of the hydrolysis of ester linkages within nucleic acids by removing nucleotide residues from the 3' or 5' end to yield 3' phosphomonoesters.
16798	hydrolase activity, acting on glycosyl bonds	F	Catalysis of the hydrolysis of any glycosyl bond.
16799	hydrolase activity, hydrolyzing N-glycosyl compounds	F	Catalysis of the hydrolysis of any N-glycosyl bond.
16801	hydrolase activity, acting on ether bonds	F	Catalysis of the hydrolysis of any ether or thioether bond, -O- or -S- respectively.
16802	trialkylsulfonium hydrolase activity	F	Catalysis of the hydrolysis of a thioether bond, -S-.
16803	ether hydrolase activity	F	Catalysis of the hydrolysis of an ether bond, -O-.
16805	dipeptidase activity	F	Catalysis of the hydrolysis of a dipeptide.
16807	cysteine-type carboxypeptidase activity	F	Catalysis of the hydrolysis of C-terminal peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile.
16810	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds	F	Catalysis of the hydrolysis of any carbon-nitrogen bond, C-N, with the exception of peptide bonds.
16811	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	F	Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in a linear amide.
16812	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides	F	Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in a cyclic amide.
16813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines	F	Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in a linear amidine, a compound of the form R-C(=NH)-NH2.
16814	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	F	Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in a cyclic amidine, a compound of the form R-C(=NH)-NH2.
16815	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in nitriles	F	Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in a nitrile, a compound containing the cyano radical, -CN.
16817	hydrolase activity, acting on acid anhydrides	F	Catalysis of the hydrolysis of any acid anhydride.
16818	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	F	Catalysis of the hydrolysis of any acid anhydride which contains phosphorus.
16819	hydrolase activity, acting on acid anhydrides, in sulfonyl-containing anhydrides	F	Catalysis of the hydrolysis of any acid anhydride which contains a sulfonyl group, -SO2-.
16820	hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances	F	Catalysis of the hydrolysis of an acid anhydride to directly drive the transport of a substance across a membrane.
16822	hydrolase activity, acting on acid carbon-carbon bonds	F	Catalysis of the hydrolysis of any acid carbon-carbon bond.
16823	hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances	F	Catalysis of the hydrolysis of any acid carbon-carbon bond in a ketonic substance, a substance containing a keto (C=O) group.
16824	hydrolase activity, acting on acid halide bonds	F	Catalysis of the hydrolysis of any acid halide bond.
16825	hydrolase activity, acting on acid phosphorus-nitrogen bonds	F	Catalysis of the hydrolysis of any acid phosphorus-nitrogen bond.
16826	hydrolase activity, acting on acid sulfur-nitrogen bonds	F	Catalysis of the hydrolysis of any acid sulfur-nitrogen bond.
16827	hydrolase activity, acting on acid carbon-phosphorus bonds	F	Catalysis of the hydrolysis of any acid carbon-phosphorus bond.
16828	hydrolase activity, acting on acid sulfur-sulfur bonds	F	Catalysis of the hydrolysis of any acid sulfur-sulfur bond.
16829	lyase activity	F	Catalysis of the cleavage of C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond. They differ from other enzymes in that two substrates are involved in one reaction direction, but only one in the other direction. When acting on the single substrate, a molecule is eliminated and this generates either a new double bond or a new ring.
16830	carbon-carbon lyase activity	F	Catalysis of the cleavage of C-C bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond.
16831	carboxy-lyase activity	F	Catalysis of the nonhydrolytic addition or removal of a carboxyl group to or from a compound.
16832	aldehyde-lyase activity	F	Catalysis of the cleavage of a C-C bond in a molecule containing a hydroxyl group and a carbonyl group to form two smaller molecules, each being an aldehyde or a ketone.
16833	oxo-acid-lyase activity	F	Catalysis of the cleavage of a C-C bond by other means than by hydrolysis or oxidation, of a 3-hydroxy acid.
16835	carbon-oxygen lyase activity	F	Catalysis of the breakage of a carbon-oxygen bond.
16836	hydro-lyase activity	F	Catalysis of the cleavage of a carbon-oxygen bond by elimination of water.
16837	carbon-oxygen lyase activity, acting on polysaccharides	F	Catalysis of the cleavage of a carbon-oxygen bond by the elimination of an alcohol from a polysaccharide.
16838	carbon-oxygen lyase activity, acting on phosphates	F	Catalysis of the cleavage of a carbon-oxygen bond by elimination of a phosphate.
16840	carbon-nitrogen lyase activity	F	Catalysis of the release of ammonia or one of its derivatives, with the formation of a double bond or ring. Enzymes with this activity may catalyze the actual elimination of the ammonia, amine or amide, e.g. CH-CH(-NH-R) = C=CH- + NH2-R. Others, however, catalyze elimination of another component, e.g. water, which is followed by spontaneous reactions that lead to breakage of the C-N bond, e.g. L-serine ammonia-lyase (EC:4.3.1.17), so that the overall reaction is C(-OH)-CH(-NH2) = CH2-CO- + NH3, i.e. an elimination with rearrangement. The sub-subclasses of EC:4.3 are the ammonia-lyases (EC:4.3.1), lyases acting on amides, amidines, etc. (EC:4.3.2), the amine-lyases (EC:4.3.3), and other carbon-nitrogen lyases (EC:4.3.99).
16841	ammonia-lyase activity	F	Catalysis of the release of ammonia by the cleavage of a carbon-nitrogen bond or the reverse reaction with ammonia as a substrate.
16842	amidine-lyase activity	F	Catalysis of the release of amides or amidines by the cleavage of a carbon-nitrogen bond or the reverse reaction with an amide or amidine as a substrate.
16843	amine-lyase activity	F	Catalysis of the release of amides by the cleavage of a carbon-nitrogen bond or the reverse reaction with an amine as a substrate.
16844	strictosidine synthase activity	F	Catalysis of the reaction: 3alpha(S)-strictosidine + H(2)O = secologanin + tryptamine.
16846	carbon-sulfur lyase activity	F	Catalysis of the elimination of hydrogen sulfide or substituted H2S.
16847	1-aminocyclopropane-1-carboxylate synthase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine(1+) = 1-aminocyclopropane-1-carboxylate + S-methyl-5'-thioadenosine + H(+).
16848	carbon-halide lyase activity	F	Catalysis of the breakage of a bond between carbon and any halogen atom.
16849	phosphorus-oxygen lyase activity	F	Catalysis of the cleavage of a phosphorus-oxygen bond by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond.
16851	magnesium chelatase activity	F	Catalysis of the reaction: ATP + H(2)O + Mg(2+) + protoporphyrin IX = ADP + 2 H(+) + magnesium protoporphyrin IX + phosphate.
16852	sirohydrochlorin cobaltochelatase activity	F	Catalysis of the reaction: sirohydrochlorin + Co2+ = cobalt-sirohydrochlorin + 2 H+.
16853	isomerase activity	F	Catalysis of the geometric or structural changes within one molecule. Isomerase is the systematic name for any enzyme of EC class 5.
16854	racemase and epimerase activity	F	Catalysis of a reaction that alters the configuration of one or more chiral centers in a molecule.
16855	racemase and epimerase activity, acting on amino acids and derivatives	F	Catalysis of a reaction that alters the configuration of one or more chiral centers in an amino acid.
16856	racemase and epimerase activity, acting on hydroxy acids and derivatives	F	Catalysis of a reaction that alters the configuration of one or more chiral centers in a hydroxy acid molecule.
16857	racemase and epimerase activity, acting on carbohydrates and derivatives	F	Catalysis of a reaction that alters the configuration of one or more chiral centers in a carbohydrate molecule.
16859	cis-trans isomerase activity	F	Catalysis of a reaction that interconverts cis and trans isomers. Atoms or groups are termed cis or trans to one another when they lie respectively on the same or on opposite sides of a reference plane identifiable as common among stereoisomers.
16860	intramolecular oxidoreductase activity	F	Catalysis of an oxidation-reduction (redox) reaction in which the hydrogen donor and acceptor are the same molecule, and no oxidized product appears.
16861	intramolecular oxidoreductase activity, interconverting aldoses and ketoses	F	Catalysis of an oxidation-reduction (redox) reaction in which the hydrogen donor and acceptor, which is an aldose or a ketose, are the same molecule, and no oxidized product appears.
16862	intramolecular oxidoreductase activity, interconverting keto- and enol-groups	F	Catalysis of an oxidation-reduction (redox) reaction in which the hydrogen donor and acceptor, which is a keto- or an enol-group, are the same molecule, and no oxidized product appears.
16863	intramolecular oxidoreductase activity, transposing C=C bonds	F	Catalysis of an oxidation-reduction (redox) reaction in which the hydrogen donor and acceptor are the same molecule, one or more carbon-carbon double bonds in the molecule are rearranged, and no oxidized product appears.
16864	intramolecular oxidoreductase activity, transposing S-S bonds	F	Catalysis of an oxidation-reduction (redox) reaction in which the hydrogen donor and acceptor are the same molecule, one or more sulfur-sulfur bonds in the molecule are rearranged, and no oxidized product appears.
16866	intramolecular transferase activity	F	Catalysis of the transfer of a functional group from one position to another within a single molecule.
16867	intramolecular transferase activity, transferring acyl groups	F	Catalysis of the transfer of an acyl group from one position to another within a single molecule.
16868	intramolecular transferase activity, phosphotransferases	F	Catalysis of the transfer of a phosphate group from one position to another within a single molecule.
16869	intramolecular transferase activity, transferring amino groups	F	Catalysis of the transfer of an amino group from one position to another within a single molecule.
16871	cycloartenol synthase activity	F	Catalysis of the reaction: (S)-2,3-epoxysqualene = cycloartenol.
16872	intramolecular lyase activity	F	The catalysis of certain rearrangements of a molecule to break or form a ring.
16874	ligase activity	F	Catalysis of the joining of two substances, or two groups within a single molecule, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate.
16875	ligase activity, forming carbon-oxygen bonds	F	Catalysis of the joining of two molecules via a carbon-oxygen bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate.
16876	ligase activity, forming aminoacyl-tRNA and related compounds	F	Catalysis of the joining of an amino acid and a nucleic acid (usually tRNA) or poly(ribitol phosphate), with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate. The reaction forms an aminoacyl-tRNA or a related compound.
16877	ligase activity, forming carbon-sulfur bonds	F	Catalysis of the joining of two molecules via a carbon-sulfur bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate.
16878	acid-thiol ligase activity	F	Catalysis of the joining of an acid and a thiol via a carbon-sulfur bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate.
16879	ligase activity, forming carbon-nitrogen bonds	F	Catalysis of the joining of two molecules, or two groups within a single molecule, via a carbon-nitrogen bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate.
16880	acid-ammonia (or amide) ligase activity	F	Catalysis of the ligation of an acid to ammonia (NH3) or an amide via a carbon-nitrogen bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate.
16881	acid-amino acid ligase activity	F	Catalysis of the ligation of an acid to an amino acid via a carbon-nitrogen bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate.
16882	cyclo-ligase activity	F	Catalysis of the joining of two groups within a single molecule via a carbon-nitrogen bond, forming heterocyclic ring, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate.
16884	carbon-nitrogen ligase activity, with glutamine as amido-N-donor	F	Catalysis of the transfer of the amide nitrogen of glutamine to a variety of substrates. GATases catalyze two separate reactions at two active sites, which are located either on a single polypeptide chain or on different subunits. In the glutaminase reaction, glutamine is hydrolyzed to glutamate and ammonia, which is added to an acceptor substrate in the synthase reaction.
16885	ligase activity, forming carbon-carbon bonds	F	Catalysis of the joining of two molecules via a carbon-carbon bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate.
16886	ligase activity, forming phosphoric ester bonds	F	Catalysis of the joining of two molecules, or two groups within a single molecule, via a phosphoric ester bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate.
16887	ATPase activity	F	Catalysis of the reaction: ATP + H2O = ADP + phosphate + 2 H+. May or may not be coupled to another reaction.
16888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters	F	Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acids by creating internal breaks to yield 5'-phosphomonoesters.
16889	endodeoxyribonuclease activity, producing 3'-phosphomonoesters	F	Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acids by creating internal breaks to yield 3'-phosphomonoesters.
16890	site-specific endodeoxyribonuclease activity, specific for altered base	F	Catalysis of the hydrolysis of ester linkages at specific sites within a deoxyribonucleic acid molecule by creating internal breaks.
16891	endoribonuclease activity, producing 5'-phosphomonoesters	F	Catalysis of the hydrolysis of ester linkages within ribonucleic acids by creating internal breaks to yield 5'-phosphomonoesters.
16892	endoribonuclease activity, producing 3'-phosphomonoesters	F	Catalysis of the hydrolysis of ester linkages within ribonucleic acids by creating internal breaks to yield 3'-phosphomonoesters.
16893	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters	F	Catalysis of the hydrolysis of ester linkages within nucleic acids by creating internal breaks to yield 5'-phosphomonoesters.
16894	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters	F	Catalysis of the hydrolysis of ester linkages within nucleic acids by creating internal breaks to yield 3'-phosphomonoesters.
16895	exodeoxyribonuclease activity, producing 5'-phosphomonoesters	F	Catalysis of the hydrolysis of ester linkages within deoxyribonucleic acids by removing nucleotide residues from the 3' or 5' end to yield 5' phosphomonoesters.
16896	exoribonuclease activity, producing 5'-phosphomonoesters	F	Catalysis of the hydrolysis of ester linkages within ribonucleic acids by removing nucleotide residues from the 3' or 5' end to yield 5' phosphomonoesters.
16897	exoribonuclease activity, producing 3'-phosphomonoesters	F	Catalysis of the hydrolysis of ester linkages within ribonucleic acids by removing nucleotide residues from the 3' or 5' end to yield 3' phosphomonoesters.
16898	oxidoreductase activity, acting on the CH-OH group of donors, cytochrome as acceptor	F	Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces a cytochrome molecule.
16899	oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor	F	Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces an oxygen molecule.
16900	oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor	F	Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces a disulfide molecule.
16901	oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor	F	Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces a quinone or a similar acceptor molecule.
16903	oxidoreductase activity, acting on the aldehyde or oxo group of donors	F	Catalysis of an oxidation-reduction (redox) reaction in which an aldehyde or ketone (oxo) group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.
16905	myosin heavy chain kinase activity	F	Catalysis of the reaction: ATP + myosin-heavy-chain = ADP + myosin-heavy-chain phosphate.
16906	sterol 3-beta-glucosyltransferase activity	F	Catalysis of the reaction: UDP-glucose + a sterol = UDP + an O-glucosylsterol.
16907	G-protein coupled acetylcholine receptor activity	F	Combining with acetylcholine and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.
16909	SAP kinase activity	F	Catalysis of the phosphorylation of proteins. A family of protein kinases that perform a crucial step in relaying signals from the plasma membrane to the nucleus. Strongly activated by stress signals such as heat or osmotic shock, DNA-damaging agents, inhibitors of protein synthesis and pro-inflammatory cytokines.
16913	follicle-stimulating hormone activity	F	The action characteristic of follicle-stimulating hormone (FSH), a gonadotrophic glycoprotein hormone secreted, in mammals, by the anterior pituitary gland. Upon receptor binding, FSH stimulates growth of Graafian follicles in the ovaries in females, and stimulates the epithelium of the seminiferous tubules to increase spermatogenesis.
16914	follicle-stimulating hormone complex	C	A gonadotrophic glycoprotein hormone secreted, in mammals, by the anterior pituitary gland; consists of alpha and beta subunits, the latter of which confers hormonal specificity.
16917	GABA receptor activity	F	Combining with gamma-aminobutyric acid (GABA), and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. (GABA, 4-aminobutyrate) is an amino acid which acts as a neurotransmitter in some organisms.
16918	retinal binding	F	Interacting selectively and non-covalently with retinal, one of the forms of vitamin A. Retinal plays an important role in the visual process in most vertebrates, combining with opsins to form visual pigments in the retina.
16920	pyroglutamyl-peptidase activity	F	Catalysis of the release of the N-terminal pyroglutamyl group from a peptide or protein.
16922	ligand-dependent nuclear receptor binding	F	Interacting selectively and non-covalently, in a ligand dependent manner, with a nuclear receptor protein.
16925	protein sumoylation	P	The process in which a SUMO protein (small ubiquitin-related modifier) is conjugated to a target protein via an isopeptide bond between the carboxyl terminus of SUMO with an epsilon-amino group of a lysine residue of the target protein.
16926	protein desumoylation	P	The process in which a SUMO protein (small ubiquitin-related modifier) is cleaved from its target protein.
16929	SUMO-specific protease activity	F	Catalysis of the hydrolysis of SUMO, a small ubiquitin-related modifier, from previously sumoylated substrates.
16933	extracellular-glycine-gated ion channel activity	F	Enables the transmembrane transfer of an ion by a channel that opens when extracellular glycine has been bound by the channel complex or one of its constituent parts.
16934	extracellular-glycine-gated chloride channel activity	F	Enables the transmembrane transfer of a chloride ion by a channel that opens when extracellular glycine has been bound by the channel complex or one of its constituent parts.
16935	glycine-gated chloride channel complex	C	A protein complex that forms a transmembrane channel through which chloride ions may pass in response to glycine binding to the channel complex or one of its constituent parts.
16936	galactoside binding	F	Interacting selectively and non-covalently with any glycoside in which the sugar group is galactose.
16937	short-branched-chain-acyl-CoA dehydrogenase activity	F	Catalysis of the reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor, where the acyl group is a short branched chain fatty acid residue.
16938	kinesin I complex	C	A complex of two kinesin heavy chains and two kinesin light chains.
16939	kinesin II complex	C	A complex consisting of two distinct motor subunits that form a heterodimer complexed with a third non-motor accessory subunit, the kinesin associated protein or KAP; the KIF3 heterodimer interacts via its C-terminal portion with KAP, which is thought to regulate the binding of the motor to cargo membranes.
16941	natriuretic peptide receptor activity	F	Combining with a natriuretic peptide and transmitting the signal to initiate a change in cell activity.
16942	insulin-like growth factor binding protein complex	C	A complex of proteins which includes the insulin-like growth factor (IGF) and a number of IGF-binding proteins. The complex plays a role in growth and development.
16964	alpha-2 macroglobulin receptor activity	F	Combining with alpha-2 macroglobulin and delivering alpha-2 macroglobulin into the cell via receptor-mediated endocytosis.
16966	nitric oxide reductase activity	F	Catalysis of the reaction: H(2)O + 2 ferricytochrome c + nitrous oxide = 2 H(+) + 2 ferrocytochrome c + 2 nitric oxide.
16971	flavin-linked sulfhydryl oxidase activity	F	Catalysis of the formation of disulfide bridges.
16972	thiol oxidase activity	F	Catalysis of the reaction: 4 R'C(R)SH + O2 = 2 R'C(R)S-S(R)CR' + 2 H2O.
16973	poly(A)+ mRNA export from nucleus	P	The directed movement of poly(A)+ mRNA out of the nucleus into the cytoplasm.
16977	chitosanase activity	F	Catalysis of the endohydrolysis of beta-1,4-linkages between N-acetyl-D-glucosamine and D-glucosamine residues in a partly acetylated chitosan.
16979	lipoate-protein ligase activity	F	Catalysis of the formation of carbon-nitrogen bonds between lipoate (5-(1,2-dithiolan-3-yl)pentanoate) and a protein.
16980	creatinase activity	F	Catalysis of the reaction: creatine + H(2)O = sarcosine + urea.
16984	ribulose-bisphosphate carboxylase activity	F	Catalysis of the reaction: D-ribulose 1,5-bisphosphate + CO2 + H2O = 2 3-phospho-D-glycerate.
16985	mannan endo-1,4-beta-mannosidase activity	F	Catalysis of the random hydrolysis of (1->4)-beta-D-mannosidic linkages in mannans, galactomannans, glucomannans, and galactoglucomannans.
16987	sigma factor activity	F	A sigma factor is the promoter specificity subunit of eubacterial-type multisubunit RNA polymerases, those whose core subunit composition is often described as alpha(2)-beta-beta-prime. (This type of multisubunit RNA polymerase complex is known to be found in eubacteria and plant plastids). Although sigma does not bind DNA on its own, when combined with the core to form the holoenzyme, this binds specifically to promoter sequences, with the sigma factor making sequence specific contacts with the promoter elements. The sigma subunit is released from the elongating form of the polymerase and is thus free to act catalytically for multiple RNA polymerase core enzymes.
16989	sigma factor antagonist activity	F	The function of binding to a sigma factor and stopping, preventing or reducing the rate of its transcriptional activity.
16990	arginine deiminase activity	F	Catalysis of the reaction: L-arginine + H2O = L-citrulline + NH3.
16992	lipoate synthase activity	F	Catalysis of the reaction: protein N6-(octanoyl)lysine + 2 sulfur + 2 S-adenosyl-L-methionine = protein N6-(lipoyl)lysine + 2 L-methionine + 2 5'-deoxyadenosyl.
16993	precorrin-8X methylmutase activity	F	Catalysis of the reaction: precorrin-8X = hydrogenobyrinate.
16994	precorrin-6A reductase activity	F	Catalysis of the reaction: precorrin-6B + NADP+ = precorrin-6A + NADPH + H+.
16995	cholesterol oxidase activity	F	Catalysis of the reaction: cholesterol + O2 = cholest-5-en-3-one + H2O2.
16996	endo-alpha-(2,8)-sialidase activity	F	Catalysis of the endohydrolysis of (2->8)-alpha-sialosyl linkages in oligo- or poly(sialic) acids.
16997	alpha-sialidase activity	F	Catalysis of the hydrolysis of alpha-glycosidic linkages in oligo- or poly(sialic) acids.
16998	cell wall macromolecule catabolic process	P	The chemical reactions and pathways resulting in the breakdown of macromolecules that form part of a cell wall.
16999	antibiotic metabolic process	P	The chemical reactions and pathways involving an antibiotic, a substance produced by or derived from certain fungi, bacteria, and other organisms, that can destroy or inhibit the growth of other microorganisms.
17000	antibiotic biosynthetic process	P	The chemical reactions and pathways resulting in the formation of an antibiotic, a substance produced by or derived from certain fungi, bacteria, and other organisms, that can destroy or inhibit the growth of other microorganisms.
17001	antibiotic catabolic process	P	The chemical reactions and pathways resulting in the breakdown of antibiotic, a substance produced by or derived from certain fungi, bacteria, and other organisms, that can destroy or inhibit the growth of other microorganisms.
17002	activin-activated receptor activity	F	Combining with activin and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. Activin is one of two gonadal glycoproteins related to transforming growth factor beta.
17003	protein-heme linkage	P	The covalent linkage of heme and a protein.
17004	cytochrome complex assembly	P	The aggregation, arrangement and bonding together of a cytochrome complex. A cytochrome complex is a protein complex in which at least one of the proteins is a cytochrome, i.e. a heme-containing protein involved in catalysis of redox reactions.
17005	3'-tyrosyl-DNA phosphodiesterase activity	F	Catalysis of the hydrolysis of 3'-phosphotyrosyl groups formed as covalent intermediates (in DNA backbone breakage) between DNA topoisomerase I and DNA.
17006	protein-tetrapyrrole linkage	P	The covalent linking of a tetrapyrrole to a protein.
17007	protein-bilin linkage	P	The covalent linkage of bilin and a protein.
17008	protein-phycobiliviolin linkage	P	The linkage of the chromophore phycobiliviolin to phycoerythrocyanin.
17009	protein-phycocyanobilin linkage	P	The linkage of the chromophore phycocyanobilin to phycocyanin or allophycocyanin.
17010	protein-phycourobilin linkage	P	The linkage of the chromophore phycourobilin to phycoerythrins.
17011	protein-phycoerythrobilin linkage	P	The linkage of the chromophore phycoerythrobilin to phycoerythrins.
17012	protein-phytochromobilin linkage	P	The linkage of the chromophore phytochromobilin to phycocyanin or allophycocyanin.
17013	protein flavinylation	P	The addition of a flavin group to a protein amino acid.
17014	protein nitrosylation	P	The covalent addition of a nitric oxide group to an amino acid within a protein.
17015	regulation of transforming growth factor beta receptor signaling pathway	P	Any process that modulates the frequency, rate or extent of activity of any TGF-beta receptor signaling pathway.
17016	Ras GTPase binding	F	Interacting selectively and non-covalently with any member of the Ras superfamily of monomeric GTPases.
17017	MAP kinase tyrosine/serine/threonine phosphatase activity	F	Catalysis of the reaction: MAP kinase serine/threonine/tyrosine phosphate + H2O = MAP kinase serine/threonine/tyrosine + phosphate.
17018	myosin phosphatase activity	F	Catalysis of the reaction: phosphomyosin + H2O = myosin + phosphate.
17020	myosin phosphatase regulator activity	F	Modulation of the activity of the enzyme myosin phosphatase.
17022	myosin binding	F	Interacting selectively and non-covalently with any part of a myosin complex; myosins are any of a superfamily of molecular motor proteins that bind to actin and use the energy of ATP hydrolysis to generate force and movement along actin filaments.
17023	myosin phosphatase complex	C	An enzyme complex that catalyzes the removal of the phosphate group from phosphomyosin.
17024	myosin I binding	F	Interacting selectively and non-covalently with a class I myosin; myosin I heavy chains are single-headed, possess tails of various lengths, and do not self-associate into bipolar filaments.
17025	TBP-class protein binding	F	Interacting selectively and non-covalently with a member of the class of TATA-binding proteins (TBP), including any of the TBP-related factors (TRFs).
17032	potassium:amino acid symporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: amino acid(out) + K+(out) = amino acid(in) + K+(in).
17034	Rap guanyl-nucleotide exchange factor activity	F	Stimulates the exchange of guanyl nucleotides associated with a GTPase of the Rap family. Under normal cellular physiological conditions, the concentration of GTP is higher than that of GDP, favoring the replacement of GDP by GTP in association with the GTPase.
17038	protein import	P	The targeting and directed movement of proteins into a cell or organelle. Not all import involves an initial targeting event.
17040	ceramidase activity	F	Catalysis of the reaction: N-acylsphingosine + H2O = a fatty acid + sphingosine.
17041	galactosylgalactosylglucosylceramidase activity	F	Catalysis of the reaction: D-galactosyl-D-galactosyl-D-glucosyl-N-acylsphingosine + H2O = lactosyl-N-acylsphingosine + D-galactose.
17042	glycosylceramidase activity	F	Catalysis of the reaction: glycosyl-N-acylsphingosine + H2O = a sugar + N-acylsphingosine.
17044	melanocyte-stimulating hormone activity	F	The action characteristic of melanocyte-stimulating hormone, any of three peptide hormones that are produced by the intermediate lobe of the pituitary gland and, upon receptor binding, cause dispersal of melanosomes in melanophores of poikilothermic vertebrates.
17045	corticotropin-releasing hormone activity	F	The action characteristic of corticotropin-releasing hormone (CRH), any of a number of peptides released by the mammalian hypothalamus into the hypophyseal-portal circulation in response to neural and/or chemical stimuli. Upon receptor binding, CRH increases the rate of corticotropin secretion by the anterior pituitary.
17046	peptide hormone binding	F	Interacting selectively and non-covalently with any peptide with hormonal activity in animals.
17048	Rho GTPase binding	F	Interacting selectively and non-covalently with Rho protein, any member of the Rho subfamily of the Ras superfamily of monomeric GTPases. Proteins in the Rho subfamily are involved in relaying signals from cell-surface receptors to the actin cytoskeleton.
17049	GTP-Rho binding	F	Interacting selectively and non-covalently with the GTP-bound form of the Rho protein.
17050	D-erythro-sphingosine kinase activity	F	Catalysis of the reaction: sphingosine + ATP = sphingosine 1-phosphate + ADP.
17051	retinol dehydratase activity	F	Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + retinol = adenosine 3',5'-bisphosphate + anhydroretinol.
17053	transcriptional repressor complex	C	A protein complex that possesses activity that prevents or downregulates transcription.
17054	negative cofactor 2 complex	C	A heterodimeric protein complex that can stably associate with TATA-binding protein on promoters, thereby preventing the assembly of transcription factors TFIIA and TFIIB and leading to repression of RNA polymerase II transcription. The two subunits, NC2alpha (Drap1) and NC2beta (Dr1), dimerize through histone fold domains of the H2A/H2B type present in the amino termini.
17055	negative regulation of RNA polymerase II transcriptional preinitiation complex assembly	P	Any process that stops, prevents, or reduces the frequency, rate or extent of RNA polymerase II transcriptional preinitiation complex assembly.
17056	structural constituent of nuclear pore	F	The action of a molecule that contributes to the structural integrity of the nuclear pore complex.
17057	6-phosphogluconolactonase activity	F	Catalysis of the reaction: 6-O-phosphono-D-glucono-1,5-lactone + H(2)O = 6-phospho-D-gluconate + H(+).
17058	FH1 domain binding	F	Interacting selectively and non-covalently with a FH1 domain of a protein, a proline-rich domain, usually located in front of a FH2 domain.
17059	serine C-palmitoyltransferase complex	C	An enzyme complex that catalyzes the transfer of a palmitoyl on to serine, forming 3-dehydro-D-sphinganine.
17060	3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity	F	Catalysis of the reaction: GDP-L-fucose + beta-D-galactosyl-(1,3)-N-acetyl-D-glucosaminyl-R = GDP + beta-D-galactosyl-(1,3)-[alpha-L-fucosyl-(1,4)]-N-acetyl-D-glucosaminyl-R.
17061	S-methyl-5-thioadenosine phosphorylase activity	F	Catalysis of the reaction: 5'-methylthioadenosine + phosphate = adenine + 5-methylthio-D-ribose 1-phosphate.
17062	respiratory chain complex III assembly	P	The aggregation, arrangement and bonding together of a set of components to form the cytochrome bc(1) complex, a transmembrane lipoprotein complex that it catalyzes the reduction of cytochrome c by accepting reducing equivalents from Coenzyme Q, by the aggregation, arrangement and bonding together of its constituents.
17064	fatty acid amide hydrolase activity	F	Catalysis of the hydrolysis of a fatty acid amide to yield a fatty acid.
17065	single-strand selective uracil DNA N-glycosylase activity	F	Catalysis of the cleavage of the N-C1' glycosidic bond between the damaged DNA base and the deoxyribose sugar, releasing a free base and leaving an apyrimidinic (AP) site. Enzymes with this activity recognize and remove uracil bases present in single-stranded DNA.
17067	tyrosine-ester sulfotransferase activity	F	Catalysis of the reaction: 3'-phospho-5'-adenylyl sulfate + L-tyrosine methyl ester = L-tyrosine methyl ester 4-sulfate + adenosine 3',5'-diphosphate + H(+).
17069	snRNA binding	F	Interacting selectively and non-covalently with a small nuclear RNA (snRNA).
17070	U6 snRNA binding	F	Interacting selectively and non-covalently with the U6 small nuclear RNA (U6 snRNA).
17071	intracellular cyclic nucleotide activated cation channel complex	C	A protein complex that forms a transmembrane channel through which cations ions may pass in response to an intracellular cyclic nucleotide binding to the channel complex or one of its constituent parts.
17075	syntaxin-1 binding	F	Interacting selectively and non-covalently with the SNAP receptor syntaxin-1.
17076	purine nucleotide binding	F	Interacting selectively and non-covalently with purine nucleotides, any compound consisting of a purine nucleoside esterified with (ortho)phosphate.
17077	oxidative phosphorylation uncoupler activity	F	Catalysis of the transfer of protons from mitochondrial intermembrane space into mitochondrial matrix, dissipating the proton gradient across the mitochondrial inner membrane established by the electron transport chain during the oxidative phosphorylation (proton leak). Proton leak uncouples the processes of electron transport/proton generation and ATP synthesis.
17080	sodium channel regulator activity	F	Modulates the activity of a sodium channel.
17081	chloride channel regulator activity	F	Modulates the activity of a chloride channel.
17082	mineralocorticoid receptor activity	F	Combining with a mineralocorticoid and transmitting the signal to the transcriptional machinery by interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription by RNA polymerase II.
17083	4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase activity	F	Catalysis of the reaction: GDP-beta-L-fucose + beta-D-galactosyl-(1,4)-N-acetyl-D-glucosaminyl-R = GDP + 1,4-beta-D-galactosyl-(1,4)-[alpha-L-fucosyl-(1,4)]-N-acetyl-D-glucosaminyl-R.
17084	delta1-pyrroline-5-carboxylate synthetase activity	F	Catalysis of the reaction: L-glutamate + ATP + NADPH = ADP + L-glutamate gamma-semialdehyde + NADP+ + phosphate.
17085	response to insecticide	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insecticide stimulus. Insecticides are chemicals used to kill insects.
17086	3-methyl-2-oxobutanoate dehydrogenase (lipoamide) complex	C	A protein complex that catalyzes the reaction 3-methyl-2-oxobutanoate + lipoamide = S-(2-methylpropanoyl)-dihydrolipoamide + carbon dioxide (CO2). This requires thiamine diphosphate; the enzyme also acts on (S)-3-methyl-2-oxopentanoate and 4-methyl-2-oxo-pentanoate.
17087	mitochondrial processing peptidase complex	C	A protein complex that consists of a catalytic alpha subunit (alpha-MPP) and a regulatory beta subunit (beta-MPP), and catalyzes the release of N-terminal targeting peptides from precursor proteins imported into the mitochondrion.
17089	glycolipid transporter activity	F	Enables the directed movement of glycolipids, compounds containing (usually) 1-4 linked monosaccharide residues joined by a glycosyl linkage to a lipid, into, out of or within a cell, or between cells.
17090	meprin A complex	C	A protein complex that is located in the cell membrane, and is involved in the metabolism of peptides, including neuropeptides. The complex has metalloendopeptidase activity that catalyzes the hydrolysis of protein and peptide substrates, preferentially on carboxyl side of hydrophobic residues.
17091	AU-rich element binding	F	Interacting selectively and non-covalently with a region of RNA containing frequent adenine and uridine bases.
17095	heparan sulfate 6-O-sulfotransferase activity	F	Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + heparan sulfate = adenosine 3',5'-bisphosphate + heparan sulfate 6-O-sulfate; results in 6-O-sulfation of glucosamine residues in heparan sulfate.
17096	acetylserotonin O-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + N-acetylserotonin = S-adenosyl-L-homocysteine + melatonin. Melatonin is also known as N-acetyl-5-methoxytryptamine.
17098	sulfonylurea receptor binding	F	Interacting selectively and non-covalently with the sulfonylurea receptor, a regulatory subunit of the ATP-sensitive potassium ion channel.
17099	very-long-chain-acyl-CoA dehydrogenase activity	F	Catalysis of the reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor, where the acyl group is a very long chain fatty acid residue. A very long-chain fatty acid is a fatty acid which has a chain length greater than C22.
17101	aminoacyl-tRNA synthetase multienzyme complex	C	A multienzyme complex found in all multicellular eukaryotes composed of eight proteins with aminoacyl-tRNA synthetase activities (abbreviated as: ArgRS, AspRS, GluProRS, GlnRS, IleRS, LeuRS, LysRS, MetRS where RS is the enzyme, preceded by the amino acid it uses as a substrate) as well as three non-synthetase proteins (p43, p38, and p18) with diverse functions. Several of these subunits are known dimers, so the total polypeptide count in the multisynthetase complex is at least fifteen. All of the enzymes in this assembly catalyze the same reaction, the covalent attachment of an amino acid to either the 2'- or 3'-hydroxyl of the 3'-terminal adenosine of tRNA, but using different substrates.
17102	methionyl glutamyl tRNA synthetase complex	C	A complex consisting of methionyl- and glutamyl-tRNA synthetases. The tRNA synthetases present in the complex bind to their cognate tRNAs more efficiently than they do as monomers.
17103	UTP:galactose-1-phosphate uridylyltransferase activity	F	Catalysis of the reaction: alpha-D-galactose 1-phosphate + UTP = diphosphate + UDP-D-galactose.
17105	acyl-CoA delta11-desaturase activity	F	Catalysis of the reaction: acyl-CoA + reduced acceptor + O2 = delta11-acyl-CoA + acceptor + 2 H2O.
17107	anion exchanger adaptor activity	F	The binding activity of a molecule that brings together an anion exchanger and one or more other molecules, permitting them to function in a coordinated way.
17108	5'-flap endonuclease activity	F	Catalysis of the cleavage of a 5' flap structure in DNA, but not other DNA structures; processes the 5' ends of Okazaki fragments in lagging strand DNA synthesis.
17109	glutamate-cysteine ligase complex	C	An enzyme complex that catalyzes the ligation of glutamate to cysteine, forming glutamylcysteine.
17110	nucleoside-diphosphatase activity	F	Catalysis of the reaction: a nucleoside diphosphate + H2O = a nucleotide + phosphate.
17111	nucleoside-triphosphatase activity	F	Catalysis of the reaction: a nucleoside triphosphate + H2O = nucleoside diphosphate + phosphate.
17112	Rab guanyl-nucleotide exchange factor activity	F	Stimulates the exchange of guanyl nucleotides associated with a GTPase of the Rab family. Under normal cellular physiological conditions, the concentration of GTP is higher than that of GDP, favoring the replacement of GDP by GTP in association with the GTPase.
17113	dihydropyrimidine dehydrogenase (NADP+) activity	F	Catalysis of the reaction: 5,6-dihydrouracil + NADP+ = uracil + NADPH + H+.
17116	single-stranded DNA-dependent ATP-dependent DNA helicase activity	F	Catalysis of the reaction: ATP + H2O = ADP + phosphate, in the presence of single-stranded DNA; drives the unwinding of a DNA helix.
17117	single-stranded DNA-dependent ATP-dependent DNA helicase complex	C	A protein complex that possesses single-stranded DNA-dependent DNA helicase activity.
17118	lipoyltransferase activity	F	Catalysis of the transfer of the lipoyl group from lipoyl-AMP to the lysine residue of lipoate-dependent enzyme.
17119	Golgi transport complex	C	A multisubunit tethering complex of the CATCHR family (complexes associated with tethering containing helical rods) that has a role in tethering vesicles to the Golgi prior to fusion. In yeast, this complex is called the Sec34/35 complex and is composed of eight subunits (Sec34p, Sec35p, Dor1p, Cod1p, Cod2p, Cod3p, Cod4p, and Cod5p). In mammals the subunits are named COG1-8.
17121	phospholipid scrambling	P	The movement of a population of phospholipid molecules from one leaflet of the plasma membrane bilayer to the opposite leaflet, resulting in loss of lipid asymmetry and surface exposure of phosphatidylserine (PS) and phosphatidylethanolamine (PE).
17122	protein N-acetylglucosaminyltransferase complex	C	Heterotrimeric enzyme complex, which in humans is composed of two large subunits of the same size, and one smaller subunit. Functions in the addition of nucleotide-activated sugars onto the polypeptide.
17124	SH3 domain binding	F	Interacting selectively and non-covalently with a SH3 domain (Src homology 3) of a protein, small protein modules containing approximately 50 amino acid residues found in a great variety of intracellular or membrane-associated proteins.
17125	deoxycytidyl transferase activity	F	Catalysis of the insertion of a dCMP residue opposite a template abasic site in DNA.
17126	nucleologenesis	P	A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a nucleolus, a small, dense body one or more of which are present in the nucleus of eukaryotic cells.
17127	cholesterol transporter activity	F	Enables the directed movement of cholesterol into, out of or within a cell, or between cells. Cholesterol is the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones.
17128	phospholipid scramblase activity	F	Catalysis of the movement of phospholipids from one membrane bilayer leaflet to the other, by an ATP-independent mechanism.
17129	triglyceride binding	F	Interacting selectively and non-covalently with any triester of glycerol.
17130	poly(C) RNA binding	F	Interacting selectively and non-covalently with a sequence of cytosine residues in an RNA molecule.
17131	uridine-rich cytoplasmic polyadenylylation element binding	F	Interacting selectively and non-covalently with U-rich sequence in the 3'-end of nuclear-transcribed mRNAs; required for cytoplasmic polyadenylylation.
17132	cyclic nucleotide-dependent guanyl-nucleotide exchange factor activity	F	Stimulates the exchange of guanyl nucleotides associated with a GTPase; dependent on the presence of a cyclic nucleotide.
17133	mitochondrial electron transfer flavoprotein complex	C	A protein complex located in the mitochondrion. It contains flavin adenine dinucleotide (FAD) that, together with an acyl-CoA dehydrogenase, forms a system that oxidizes an acyl-CoA molecule and reduces ubiquinone and other acceptors in the mitochondrial electron transport system.
17134	fibroblast growth factor binding	F	Interacting selectively and non-covalently with a fibroblast growth factor.
17136	NAD-dependent histone deacetylase activity	F	Catalysis of the reaction: histone N6-acetyl-L-lysine + H2O = histone L-lysine + acetate. This reaction requires the presence of NAD, and represents the removal of an acetyl group from a histone.
17137	Rab GTPase binding	F	Interacting selectively and non-covalently with Rab protein, any member of the Rab subfamily of the Ras superfamily of monomeric GTPases.
17143	insecticide metabolic process	P	The chemical reactions and pathways involving insecticides, chemicals used to kill insects.
17144	drug metabolic process	P	The chemical reactions and pathways involving a drug, a substance used in the diagnosis, treatment or prevention of a disease; as used here antibiotic substances (see antibiotic metabolism) are considered to be drugs, even if not used in medical or veterinary practice.
17145	stem cell division	P	The self-renewing division of a stem cell. A stem cell is an undifferentiated cell, in the embryo or adult, that can undergo unlimited division and give rise to one or several different cell types.
17146	NMDA selective glutamate receptor complex	C	An assembly of four or five subunits which form a structure with an extracellular N-terminus and a large loop that together form the ligand binding domain. The C-terminus is intracellular. The ionotropic glutamate receptor complex itself acts as a ligand gated ion channel; on binding glutamate, charged ions pass through a channel in the center of the receptor complex. NMDA receptors are composed of assemblies of NR1 subunits (Figure 3) and NR2 subunits, which can be one of four separate gene products (NR2A-D). Expression of both subunits are required to form functional channels. The glutamate binding domain is formed at the junction of NR1 and NR2 subunits. NMDA receptors are permeable to calcium ions as well as being permeable to other ions. Thus NMDA receptor activation leads to a calcium influx into the post-synaptic cells, a signal thought to be crucial for the induction of NMDA-receptor dependent LTP and LTD.
17147	Wnt-protein binding	F	Interacting selectively and non-covalently with Wnt-protein, a secreted growth factor involved in signaling.
17148	negative regulation of translation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA.
17150	tRNA dihydrouridine synthase activity	F	Catalysis of the reaction: tRNA-uracil + acceptor = tRNA-dihydrouridine + reduced acceptor.
17151	DEAD/H-box RNA helicase binding	F	Interacting selectively and non-covalently with the enzyme DEAD/H-box RNA helicase.
17153	sodium:dicarboxylate symporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: dicarboxylate(out) + Na+(out) = dicarboxylate(in) + Na+(in).
17154	semaphorin receptor activity	F	Combining with a semaphorin, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
17156	calcium ion regulated exocytosis	P	The release of intracellular molecules (e.g. hormones, matrix proteins) contained within a membrane-bounded vesicle by fusion of the vesicle with the plasma membrane of a cell, induced by a rise in cytosolic calcium-ion levels.
17157	regulation of exocytosis	P	Any process that modulates the frequency, rate or extent of exocytosis.
17158	regulation of calcium ion-dependent exocytosis	P	Any process that modulates the frequency, rate or extent of calcium ion-dependent exocytosis.
17159	pantetheine hydrolase activity	F	Catalysis of the reaction: (R)-pantetheine + H(2)O = (R)-pantothenate + cysteamine.
17160	Ral GTPase binding	F	Interacting selectively and non-covalently with Ral protein, any member of the Ral subfamily of the Ras superfamily of monomeric GTPases.
17161	inositol-1,3,4-trisphosphate 4-phosphatase activity	F	Catalysis of the reaction: D-myo-inositol 1,3,4-trisphosphate + H2O = myo-inositol 1,3-bisphosphate + phosphate.
17162	aryl hydrocarbon receptor binding	F	Interacting selectively and non-covalently with an aryl hydrocarbon receptor.
17166	vinculin binding	F	Interacting selectively and non-covalently with vinculin, a protein found in muscle, fibroblasts, and epithelial cells that binds actin and appears to mediate attachment of actin filaments to integral proteins of the plasma membrane.
17168	5-oxoprolinase (ATP-hydrolyzing) activity	F	Catalysis of the reaction: 5-oxo-L-proline + ATP + 2 H(2)O = L-glutamate + ADP + 2 H(+) + phosphate.
17169	CDP-alcohol phosphatidyltransferase activity	F	Catalysis of the reaction: CDP + alcohol = CMP + phosphatidyl alcohol.
17171	serine hydrolase activity	F	Catalysis of the hydrolysis of a substrate by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine).
17172	cysteine dioxygenase activity	F	Catalysis of the reaction: L-cysteine + O(2) = 3-sulfino-L-alanine + H(+).
17174	glycine N-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + glycine = S-adenosyl-L-homocysteine + sarcosine.
17176	phosphatidylinositol N-acetylglucosaminyltransferase activity	F	Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + phosphatidylinositol = UDP + N-acetyl-D-glucosaminylphosphatidylinositol.
17177	glucosidase II complex	C	A heterodimeric complex that catalyzes the trimming of glucose residues from N-linked core glycans on newly synthesized glycoproteins.
17178	diphthine-ammonia ligase activity	F	Catalysis of the reaction: ATP + diphthine + NH(4)(+) = ADP + diphthamide + H(+) + phosphate.
17179	peptidyl-diphthine metabolic process	P	The chemical reactions and pathways involving peptidyl-diphthine, a modified histidine residue.
17180	peptidyl-diphthine biosynthetic process from peptidyl-histidine	P	The chemical reactions and pathways resulting in the formation of peptidyl-diphthine from other compounds, including peptidyl-histidine.
17181	peptidyl-diphthine catabolic process	P	The chemical reactions and pathways resulting in the breakdown of peptidyl-diphthine, a modified histidine residue.
17182	peptidyl-diphthamide metabolic process	P	The chemical reactions and pathways involving peptidyl-diphthamide, a modified histidine residue.
17183	peptidyl-diphthamide biosynthetic process from peptidyl-histidine	P	The modification of peptidyl-histidine to 2'-(3-carboxamido-3-(trimethylammonio)propyl)-L-histidine, known as diphthamide, found in translation elongation factor EF-2. The process occurs in eukaryotes and archaea but not eubacteria.
17184	peptidyl-diphthamide catabolic process	P	The chemical reactions and pathways resulting in the breakdown of peptidyl-diphthamide, a modified histidine residue.
17185	peptidyl-lysine hydroxylation	P	The hydroxylation of peptidyl-lysine to form peptidyl-hydroxylysine.
17186	peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase	P	The chemical reactions and pathways resulting in the formation of peptidyl-pyroglutamic acid, catalyzed by glutaminyl-peptide cyclotransferase.
17187	peptidyl-glutamic acid carboxylation	P	The gamma-carboxylation of peptidyl-glutamic acid; catalyzed by the vitamin K dependent gamma-glutamyl carboxylase.
17188	aspartate N-acetyltransferase activity	F	Catalysis of the reaction: L-aspartate + acetyl-CoA = N-acetyl-L-aspartate + CoA + H(+).
17189	N-terminal peptidyl-alanine acetylation	P	The acetylation of the N-terminal alanine of proteins; catalyzed by peptide alpha-N-acetyltransferase or other enzymes of this class, such as ribosomal-protein-alanine N-acetyltransferase.
17190	N-terminal peptidyl-aspartic acid acetylation	P	The acetylation of the N-terminal aspartic acid of proteins; catalyzed by aspartate N-acetyltransferase.
17192	N-terminal peptidyl-glutamine acetylation	P	The acetylation of a glutamine residue in protein to form the N5-methyl-L-glutamine derivative. The occurrence of this modification has not been confirmed. Its annotation in sequence databases is either due to the misidentification of 2-pyrrolidone-5-carboxylic acid, or to inappropriate homolog comparisons when proteolytic modification is more probable.
17193	N-terminal peptidyl-glycine acetylation	P	The acetylation of the N-terminal glycine of proteins to form the derivative N-acetylglycine.
17194	N-terminal peptidyl-isoleucine acetylation	P	The acetylation of the N-terminal isoleucine of proteins to form the derivative N-acetyl-L-isoleucine. The occurrence of this modification has not been confirmed.
17195	N-terminal peptidyl-lysine N2-acetylation	P	The acetylation of the N-terminal lysine of proteins to form the derivative N2-acetyl-L-lysine. The occurrence of this modification has not been confirmed.
17196	N-terminal peptidyl-methionine acetylation	P	The acetylation of the N-terminal methionine of proteins to form the derivative N-acetyl-L-methionine.
17197	N-terminal peptidyl-proline acetylation	P	The acetylation of the N-terminal proline of proteins to form the derivative N-acetyl-L-proline.
17198	N-terminal peptidyl-serine acetylation	P	The acetylation of the N-terminal serine of proteins to form the derivative N-acetyl-L-serine.
17199	N-terminal peptidyl-threonine acetylation	P	The acetylation of the N-terminal threonine of proteins to form the derivative N-acetyl-L-threonine; catalyzed by peptide alpha-N-acetyltransferase.
18000	N-terminal peptidyl-tyrosine acetylation	P	The acetylation of the N-terminal tyrosine of proteins to form the derivative N-acetyl-L-tyrosine.
18001	N-terminal peptidyl-valine acetylation	P	The acetylation of the N-terminal tyrosine of proteins to form the derivative N-acetyl-L-valine.
18002	N-terminal peptidyl-glutamic acid acetylation	P	The acetylation of the N-terminal glutamic acid of proteins to form the derivate acetyl-glutamic acid.
18003	peptidyl-lysine N6-acetylation	P	The acetylation of the peptidyl-lysine of proteins to form the derivative peptidyl-N6-acetyl-L-lysine.
18004	N-terminal protein formylation	P	The formylation of the N-terminal amino acid of proteins.
18005	N-terminal peptidyl-glycine N-formylation	P	The formylation of the N-terminal glycine of proteins to form the derivative N-formylglycine.
18006	N-terminal protein amino acid glucuronylation	P	The glucuronylation of the N-terminal amino acid of proteins.
18007	N-terminal peptidyl-glycine N-glucuronylation	P	The glucuronylation of the N-terminal glycine of proteins to form the derivative D-glucuronyl-N-glycine.
18008	N-terminal peptidyl-glycine N-myristoylation	P	The myristoylation of the N-terminal glycine of proteins to form the derivative N-myristoyl-glycine.
18009	N-terminal peptidyl-L-cysteine N-palmitoylation	P	The covalent attachment of a palmitoyl group to a nitrogen (N) atom in an N-terminal cysteine residue to form N-palmitoyl-L-cysteine.
18010	glycoprotein N-palmitoyltransferase activity	F	Catalysis of the reaction: palmitoyl-CoA + glycoprotein = CoA + N-palmitoylglycoprotein.
18011	N-terminal peptidyl-alanine methylation	P	The methylation of the N-terminal alanine of proteins.
18012	N-terminal peptidyl-alanine trimethylation	P	The trimethylation of the N-terminal alanine of proteins to form the derivative peptidyl-N,N,N-trimethyl-L-alanine.
18013	N-terminal peptidyl-glycine methylation	P	The methylation of the N-terminal glycine of proteins to form the derivative N-methylglycine.
18014	N-terminal peptidyl-methionine methylation	P	The methylation of the N-terminal methionine of proteins to form the derivative N-methyl-L-methionine.
18015	N-terminal peptidyl-phenylalanine methylation	P	The methylation of the N-terminal phenylalanine of proteins to form the derivative N-methyl-L-phenylalanine.
18016	N-terminal peptidyl-proline dimethylation	P	The methylation of the N-terminal proline of proteins to form the derivative N,N-dimethyl-L-proline.
18019	N-terminal peptidyl-glutamine methylation	P	The methylation of a glutamine residue in proteins to form the peptidyl-N5-methyl-L-glutamine derivative.
18020	peptidyl-glutamic acid methylation	P	The addition of a methyl group to a glutamic acid residue in a protein.
18021	peptidyl-histidine methylation	P	The methylation of peptidyl-L-histidine to form peptidyl-L-1'-methyl-L-histidine (otherwise known as tau-methylhistidine, tele-methylhistidine) or peptidyl-L-3'-methyl-L-histidine (otherwise known as pi-methylhistidine, pros-methylhistidine).
18022	peptidyl-lysine methylation	P	The methylation of peptidyl-lysine to form either the mono-, di- or trimethylated derivative.
18023	peptidyl-lysine trimethylation	P	The methylation of peptidyl-lysine to form peptidyl-N6,N6,N6-trimethyl-L-lysine.
18024	histone-lysine N-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + histone L-lysine = S-adenosyl-L-homocysteine + histone N6-methyl-L-lysine. The methylation of peptidyl-lysine in histones forms N6-methyl-L-lysine, N6,N6-dimethyl-L-lysine and N6,N6,N6-trimethyl-L-lysine derivatives.
18025	calmodulin-lysine N-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + calmodulin L-lysine = S-adenosyl-L-homocysteine + calmodulin N6-methyl-L-lysine.
18026	peptidyl-lysine monomethylation	P	The methylation of peptidyl-lysine to form peptidyl-N6-methyl-L-lysine.
18027	peptidyl-lysine dimethylation	P	The methylation of peptidyl-lysine to form peptidyl-N6,N6-dimethyl-L-lysine.
18028	peptidyl-lysine myristoylation	P	The myristoylation of peptidyl-lysine to form peptidyl-N6-myristoyl-L-lysine.
18029	peptidyl-lysine palmitoylation	P	The palmitoylation of peptidyl-lysine to form peptidyl-N6-palmitoyl-L-lysine.
18030	peptidyl-lysine N6-myristoyltransferase activity	F	Catalysis of the transfer of a myristoyl group to the N6 nitrogen atom on a lysine residue of a peptide or protein molecule.
18031	peptidyl-lysine N6-palmitoyltransferase activity	F	Catalysis of the transfer of a palmitoyl group to the N6 nitrogen atom on a lysine residue of a peptide or protein molecule.
18032	protein amidation	P	Addition of an amide group from a glycine to a protein amino acid.
18033	protein C-terminal amidation	P	The formation of a C-terminal amide by hydrolysis and oxidation of an interior peptide in a secreted protein.
18034	C-terminal peptidyl-alanine amidation	P	The formation of a C-terminal peptidyl-alanine amide by hydrolysis and oxidation of an interior Ala-Gly peptide in a secreted protein.
18035	C-terminal peptidyl-arginine amidation	P	The formation of a C-terminal peptidyl-arginine amide by hydrolysis and oxidation of an interior Arg-Gly peptide in a secreted protein.
18036	C-terminal peptidyl-asparagine amidation	P	The formation of a C-terminal peptidyl-asparagine amide by hydrolysis and oxidation of an interior Asn-Gly peptide in a secreted protein.
18037	C-terminal peptidyl-aspartic acid amidation	P	The formation of a C-terminal peptidyl-aspartic acid 1-amide by hydrolysis and oxidation of an interior Asp-Gly peptide in a secreted protein.
18038	C-terminal peptidyl-cysteine amidation	P	The formation of a C-terminal peptidyl-cysteine amide by hydrolysis and oxidation of an interior Cys-Gly peptide in a secreted protein.
18039	C-terminal peptidyl-glutamine amidation	P	The formation of a C-terminal peptidyl-glutamine amide by hydrolysis and oxidation of an interior Gln-Gly peptide in a secreted protein.
18040	C-terminal peptidyl-glutamic acid amidation	P	The formation of a C-terminal peptidyl-glutamic acid amide by hydrolysis and oxidation of an interior Glu-Gly peptide in a secreted protein.
18041	C-terminal peptidyl-glycine amidation	P	The formation of a C-terminal peptidyl-glycine acid amide by hydrolysis and oxidation of an interior Gly-Gly peptide in a secreted protein.
18042	C-terminal peptidyl-histidine amidation	P	The formation of a C-terminal peptidyl-histidine amide by hydrolysis and oxidation of an interior His-Gly peptide in a secreted protein.
18043	C-terminal peptidyl-isoleucine amidation	P	The formation of a C-terminal peptidyl-isoleucine amide by hydrolysis and oxidation of an interior Ile-Gly peptide in a secreted protein.
18044	C-terminal peptidyl-leucine amidation	P	The formation of a C-terminal peptidyl-leucine amide by hydrolysis and oxidation of an interior Leu-Gly peptide in a secreted protein.
18045	C-terminal peptidyl-lysine amidation	P	The formation of a C-terminal peptidyl-lysine amide by hydrolysis and oxidation of an interior Lys-Gly peptide in a secreted protein.
18046	C-terminal peptidyl-methionine amidation	P	The formation of a C-terminal peptidyl-methionine amide by hydrolysis and oxidation of an interior Met-Gly peptide in a secreted protein.
18047	C-terminal peptidyl-phenylalanine amidation	P	The formation of a C-terminal peptidyl-phenylalanine amide by hydrolysis and oxidation of an interior Phe-Gly peptide in a secreted protein.
18048	C-terminal peptidyl-proline amidation	P	The formation of a C-terminal peptidyl-proline amide by hydrolysis and oxidation of an interior Pro-Gly peptide in a secreted protein.
18049	C-terminal peptidyl-serine amidation	P	The formation of a C-terminal peptidyl-serine amide by hydrolysis and oxidation of an interior Ser-Gly peptide in a secreted protein.
18050	C-terminal peptidyl-threonine amidation	P	The formation of a C-terminal peptidyl-threonine amide by hydrolysis and oxidation of an interior Thr-Gly peptide in a secreted protein.
18051	C-terminal peptidyl-tryptophan amidation	P	The formation of a C-terminal peptidyl-tryptophan amide by hydrolysis and oxidation of an interior Trp-Gly peptide in a secreted protein.
18052	C-terminal peptidyl-tyrosine amidation	P	The formation of a C-terminal peptidyl-tyrosine amide by hydrolysis and oxidation of an interior Tyr-Gly peptide in a secreted protein.
18053	C-terminal peptidyl-valine amidation	P	The formation of a C-terminal peptidyl-valine amide by hydrolysis and oxidation of an interior Val-Gly peptide in a secreted protein.
18054	peptidyl-lysine biotinylation	P	The covalent modification of peptidyl-lysine by biotin to form peptidyl-N6-biotinyl-L-lysine.
18055	peptidyl-lysine lipoylation	P	The lipoylation of peptidyl-lysine to form peptidyl-N6-lipoyl-L-lysine.
18057	peptidyl-lysine oxidation	P	The oxidation of the terminal amino-methylene groups of peptidyl-L-lysine or peptidyl-5-hydroxy-L-lysine to aldehyde groups to form allysine or hydroxyallysine residues, respectively; these are intermediates in the formation of covalent cross-links between adjacent polypeptide chains in proteins such as collagens.
18058	N-terminal protein amino acid deamination, from amino carbon	P	The oxidative deamination of the alpha carbon of an encoded N-terminal amino acid, to form pyruvic acid retaining an amide bond between its 1-carboxyl group and the adjacent residue. The pyruvate 2-oxo group may become an enzyme active site, or it may be reduced to an alcohol.
18059	N-terminal peptidyl-serine deamination	P	The oxidative deamination of N-terminal peptidyl-serine to form pyruvic acid with an amide bond between its 1-carboxyl group and the N-terminal residue.
18060	N-terminal peptidyl-cysteine deamination	P	The oxidative deamination of N-terminal peptidyl-cysteine to form pyruvic acid with an amide bond between its 1-carboxyl group and the N-terminal residue.
18061	peptidyl-L-3-phenyllactic acid biosynthetic process from peptidyl-phenylalanine	P	The modification of a N-terminal peptidyl-phenylalanine residue by either oxidative deamination or by transamination and subsequent reduction to form peptidyl-L-3-phenyllactic acid.
18062	peptidyl-tryptophan succinylation	P	The modification of an N-terminal peptidyl-tryptophan residue to form peptidyl-N2-succinyl-L-tryptophan.
18063	cytochrome c-heme linkage	P	The linkage of cytochromes and other heme proteins to heme.
18064	protein-histidine N-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + protein L-histidine = S-adenosyl-L-homocysteine + protein N-methyl-L-histidine.
18065	protein-cofactor linkage	P	The covalent attachment of a cofactor to a protein.
18067	peptidyl-L-3',4'-dihydroxyphenylalanine biosynthetic process from peptidyl-tyrosine	P	The modification of protein tyrosine to peptidyl-L-3',4'-dihydroxyphenylalanine (DOPA).
18068	peptidyl-L-2',4',5'-topaquinone biosynthetic process from peptidyl-tyrosine	P	The modification of protein tyrosine to L-2',4',5'-topaquinone, characteristic of the active site of copper amine oxidases.
18069	peptide cross-linking via 4'-(L-tryptophan)-L-tryptophyl quinone	P	The cross-linking of a tryptophan residue to tryptophyl quinone to form 4'-(L-tryptophan)-L-tryptophyl quinone, a cofactor found at the active site of methylamine dehydrogenase.
18070	peptidyl-serine phosphopantetheinylation	P	The phosphopantetheinylation of peptidyl-serine to form peptidyl-O-phosphopantetheine-L-serine.
18071	NAD(P)-cysteine ADP-ribosyltransferase activity	F	Catalysis of the reaction: NAD(P)+ + L-cysteine = nicotinamide + N2-(ADP-D-ribosyl)-L-cysteine.
18072	peptidyl-L-glutamyl 5-glycerylphosphorylethanolamine biosynthetic process from peptidyl-glutamic acid	P	The modification of peptidyl-glutamic acid residues by the covalent attachment of ethanolamine, itself further modified by the addition of a phosphoglycerol unit.
18073	protein bromination	P	The addition of one or more bromine atoms to an amino acid residue in a protein.
18074	peptidyl-histidine bromination	P	The bromination of peptidyl-histidine to form peptidyl-L-bromohistidine; the position of the bromine substitution is unknown.
18075	peptidyl-phenylalanine bromination	P	The bromination of phenylalanine.
18076	N-terminal peptidyl-lysine acetylation	P	The acetylation of the N-terminal lysine of proteins.
18077	protein iodination	P	The addition of one or more iodine atoms to an amino acid residue in a protein.
18078	peptidyl-thyronine iodination	P	The iodination of peptidyl-thyronine, formed from tyrosine.
18079	protein halogenation	P	The addition of a halogen to a protein amino acid.
18080	peptidyl-tryptophan bromination	P	The bromination of peptidyl-tryptophan, to form peptidyl-L-6'-bromotryptophan.
18081	peptide cross-linking via lanthionine or 3-methyl-lanthionine	P	The synthesis of (2R,6R)-lanthionine, sn-(2S,6R)-lanthionine or (2S,3S,6R)-3-methyl-lanthionine, forming an intra-polypeptide cross-link between peptidyl-cysteine, and peptidyl-serine or peptidyl-threonine; dehydration of the serine or threonine residue to the alpha,beta-unsaturated amino acid is the first step; a bond then forms between the ethylene (ethene) group thus formed and the sulfur atom of a cysteine, with the inversion of the configuration of the alpha carbon of the serine or threonine occurring during the process.
18082	peptidyl-(Z)-dehydrobutyrine biosynthetic process from peptidyl-threonine	P	The formation of (Z)-dehydrobutyrine by the dehydration of peptidyl-threonine.
18083	peptidyl-L-3-oxoalanine biosynthetic process from peptidyl-cysteine or peptidyl-serine	P	The modification of peptidyl-cysteine or peptidyl-serine to peptidyl-L-3-oxoalanine; characteristic of the active sites of arylsulfatases.
18084	peptidyl-lactic acid biosynthetic process from peptidyl-serine	P	The modification of N-terminal peptidyl-serine to lactic acid.
18085	peptidyl-L-amino acid racemization	P	The process of conversion of a L-amino acid into its enantiomer, the corresponding D-amino acid.
18091	peptidyl-asparagine racemization	P	The racemization of peptidyl-asparagine.
18094	protein polyglycylation	P	The addition of glycyl units covalently bound to the gamma carboxyl group peptidyl-glutamic acid.
18095	protein polyglutamylation	P	The addition of one or more alpha-linked glutamyl units to the gamma carboxyl group of peptidyl-glutamic acid.
18096	peptide cross-linking via S-(2-aminovinyl)-D-cysteine	P	The synthesis of (S,Z)-S-(2-aminovinyl)cysteine forming an intra-polypeptide cross-link between serine and cysteine.
18097	protein-chromophore linkage via peptidyl-S-4-hydroxycinnamyl-L-cysteine	P	The synthesis of the chromophore S-4-hydroxycinnamyl-L-cysteine.
18101	protein citrullination	P	The hydrolysis of peptidyl-arginine to form peptidyl-citrulline.
18102	peptidyl-arginine hydroxylation to peptidyl-4-hydroxy-L-arginine	P	The hydroxylation of peptidyl-arginine to form peptidyl-4-hydroxy-L-arginine.
18103	protein C-linked glycosylation	P	A protein glycosylation process in which a carbohydrate or carbohydrate derivative unit is added to a protein via a C atom.
18104	peptidoglycan-protein cross-linking	P	The process of covalently linking peptidoglycan (murein) to proteins.
18105	peptidyl-serine phosphorylation	P	The phosphorylation of peptidyl-serine to form peptidyl-O-phospho-L-serine.
18106	peptidyl-histidine phosphorylation	P	The phosphorylation of peptidyl-histidine to form peptidyl-1'-phospho-L-histidine (otherwise known as tau-phosphohistidine, tele-phosphohistidine) or peptidyl-3'-phospho-L-histidine (otherwise known as pi-phosphohistidine, pros-phosphohistidine).
18107	peptidyl-threonine phosphorylation	P	The phosphorylation of peptidyl-threonine to form peptidyl-O-phospho-L-threonine.
18108	peptidyl-tyrosine phosphorylation	P	The phosphorylation of peptidyl-tyrosine to form peptidyl-O4'-phospho-L-tyrosine.
18109	peptidyl-arginine phosphorylation	P	The phosphorylation of peptidyl-arginine to form omega-N-phospho-L-arginine.
18110	histone arginine kinase activity	F	Catalysis of the reaction: histone L-arginine + ATP = histone N(omega)-phospho-L-arginine + ADP + 2 H(+).
18111	methionine racemase activity	F	Catalysis of the reaction: L-methionine = D-methionine.
18112	proline racemase activity	F	Catalysis of the reaction: L-proline = D-proline.
18113	lysine racemase activity	F	Catalysis of the reaction: L-lysine = D-lysine.
18114	threonine racemase activity	F	Catalysis of the reaction: L-threonine = D-threonine.
18115	peptidyl-S-diphytanylglycerol diether-L-cysteine biosynthetic process from peptidyl-cysteine	P	The modification of cysteine to form peptidyl-S-diphytanylglycerol diether-L-cysteine.
18116	peptidyl-lysine adenylylation	P	The adenylylation of peptidyl-lysine to form peptidyl-N6-(phospho-5'-adenosine)-L-lysine.
18117	protein adenylylation	P	The addition of an adenylyl group (adenosine 5'-monophosphate; AMP) to a protein amino acid.
18118	peptidyl-L-cysteine glutathione disulfide biosynthetic process from peptidyl-cysteine	P	The modification of peptidyl-cysteine by covalent addition of glutathione to form peptidyl-L-cysteine glutathione disulfide.
18119	peptidyl-cysteine S-nitrosylation	P	The covalent addition of a nitric oxide (NO) group to the sulphur (S) atom of a cysteine residue in a protein, to form peptidyl-S-nitrosyl-L-cysteine.
18120	peptidyl-arginine ADP-ribosylation	P	The transfer, from NAD, of ADP-ribose to peptidyl-arginine to form omega-N-(ADP-ribosyl)-L-arginine.
18121	NAD(P)-asparagine ADP-ribosyltransferase activity	F	Catalysis of the reaction: NAD(P)+ + L-asparagine = nicotinamide + N2-(ADP-D-ribosyl)-L-asparagine.
18122	peptidyl-asparagine ADP-ribosylation	P	The transfer, from NAD, of ADP-ribose to peptidyl-asparagine to form peptidyl-N4-(ADP-ribosyl)-L-asparagine.
18123	peptidyl-cysteine ADP-ribosylation	P	The transfer, from NAD, of ADP-ribose to peptidyl-cysteine to form peptidyl-S-(ADP-ribosyl)-L-cysteine.
18124	peptide cross-linking via 5'-(N6-L-lysine)-L-topaquinone	P	The cross-linking of the epsilon-amino group of a peptidyl-lysine with peptidyl-topaquinone, a modified tyrosine residue.
18125	peptidyl-cysteine methylation	P	The methylation of peptidyl-cysteine to form peptidyl-S-methyl-L-cysteine.
18126	protein hydroxylation	P	The addition of a hydroxy group to a protein amino acid.
18127	NAD(P)-serine ADP-ribosyltransferase activity	F	Catalysis of the reaction: NAD(P)+ + L-serine = nicotinamide + N2-(ADP-D-ribosyl)-L-serine.
18129	peptidyl-oxazoline dehydrogenase activity	F	Catalysis of the reduction of a peptide-linked oxazoline to oxazole.
18130	heterocycle biosynthetic process	P	The chemical reactions and pathways resulting in the formation of heterocyclic compounds, those with a cyclic molecular structure and at least two different atoms in the ring (or rings).
18131	oxazole or thiazole biosynthetic process	P	The chemical reactions and pathways resulting in the formation of oxazole or thiazole, five-membered heterocyclic ring structures containing an oxygen and a sulfur, respectively, in the 1-position and a nitrogen in the 3-position.
18132	peptide cross-linking via L-cysteine oxazolecarboxylic acid	P	The chemical reactions and pathways resulting in the formation of a peptidyl serine-peptidyl cysteine cross-link by the condensation of a serine hydroxyl with the carbonyl of the preceding residue and alpha-beta dehydrogenation.
18133	peptide cross-linking via L-cysteine oxazolinecarboxylic acid	P	The chemical reactions and pathways resulting in the formation of a peptidyl serine-peptidyl cysteine cross-link by the condensation of a serine hydroxyl with the carbonyl of the preceding residue.
18134	peptide cross-linking via glycine oxazolecarboxylic acid	P	The chemical reactions and pathways resulting in the formation of a peptidyl serine-peptidyl glycine cross-link by the condensation of a serine hydroxyl with the carbonyl of the preceding residue and alpha-beta dehydrogenation.
18136	peptidyl-thiazoline dehydrogenase activity	F	Catalysis of the reduction of a peptide-linked thiazoline to thiazole.
18137	peptide cross-linking via glycine thiazolecarboxylic acid	P	The chemical reactions and pathways resulting in the formation of a peptidyl cysteine-peptidyl glycine cross-link by the condensation of a cysteine thiol with the carbonyl of the preceding residue and alpha-beta dehydrogenation.
18138	peptide cross-linking via L-serine thiazolecarboxylic acid	P	The chemical reactions and pathways resulting in the formation of a peptidyl cysteine-peptidyl serine cross-link by the condensation of a cysteine thiol with the carbonyl of the preceding residue and alpha-beta dehydrogenation.
18139	peptide cross-linking via L-phenylalanine thiazolecarboxylic acid	P	The chemical reactions and pathways resulting in the formation of a peptidyl cysteine-peptidyl phenylalanine cross-link by the condensation of a cysteine thiol with the carbonyl of the preceding residue and alpha-beta dehydrogenation.
18140	peptide cross-linking via L-cysteine thiazolecarboxylic acid	P	The chemical reactions and pathways resulting in the formation of a peptidyl cysteine-peptidyl cysteine cross-link by the condensation of a cysteine thiol with the carbonyl of the preceding residue and alpha-beta dehydrogenation.
18141	peptide cross-linking via L-lysine thiazolecarboxylic acid	P	The chemical reactions and pathways resulting in the formation of a peptidyl cysteine-peptidyl lysine cross-link by the condensation of a cysteine thiol with the carbonyl of the preceding residue and alpha-beta dehydrogenation.
18142	protein-DNA covalent cross-linking	P	The formation of a covalent cross-link between DNA and a protein.
18143	nucleic acid-protein covalent cross-linking	P	The formation of a covalent cross-link between a nucleic acid and a protein.
18144	RNA-protein covalent cross-linking	P	The formation of a covalent cross-link between RNA and a protein.
18145	protein-DNA covalent cross-linking via peptidyl-serine	P	The formation of a covalent cross-link between DNA and a peptidyl-serine residue by the formation of O-(phospho-5'-DNA)-L-serine.
18146	keratan sulfate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of keratan sulfate, a glycosaminoglycan with repeat units consisting of beta-1,4-linked D-galactopyranosyl-beta-(1,4)-N-acetyl-D-glucosamine 6-sulfate and with variable amounts of fucose, sialic acid and mannose units; keratan sulfate chains are covalently linked by a glycosidic attachment through the trisaccharide galactosyl-galactosyl-xylose to peptidyl-threonine or serine residues.
18147	molybdenum incorporation via L-selenocysteinyl molybdenum bis(molybdopterin guanine dinucleotide)	P	The incorporation of molybdenum into a protein via L-selenocysteinyl molybdenum bis(molybdopterin guanine dinucleotide).
18148	RNA-protein covalent cross-linking via peptidyl-tyrosine	P	The formation of a covalent cross-link between RNA and a peptidyl-tyrosine residue by the formation of O4'-(phospho-5'-RNA)-L-tyrosine.
18149	peptide cross-linking	P	The formation of a covalent cross-link between or within protein chains.
18150	peptide cross-linking via 3-(3'-L-histidyl)-L-tyrosine	P	The modification of peptidyl-histidine and peptidyl-tyrosine to form a 3-(3'-L-histidyl)-L-tyrosine protein cross-link.
18151	peptide cross-linking via L-histidyl-L-tyrosine	P	The modification of peptidyl-histidine and peptidyl-tyrosine to form a protein cross-link.
18152	peptide cross-linking via 3'-(1'-L-histidyl)-L-tyrosine	P	The modification of peptidyl-histidine and peptidyl-tyrosine to form a 3'-(1'-L-histidyl)-L-tyrosine protein cross-link.
18153	isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine	P	The formation of an isopeptide cross-link between peptidyl-lysine and peptidyl-glutamine to produce N6-(L-isoglutamyl)-L-lysine.
18154	peptide cross-linking via (2R,6R)-lanthionine	P	The formation of a protein-protein cross-link between peptidyl-serine and peptidyl-cysteine by the synthesis of (2R,6R)-lanthionine (L-lanthionine).
18155	peptide cross-linking via sn-(2S,6R)-lanthionine	P	The formation of a protein-protein cross-link between peptidyl-serine and peptidyl-cysteine by the synthesis of sn-(2S,6R)-lanthionine (meso-lanthione).
18156	peptide cross-linking via (2S,3S,6R)-3-methyl-lanthionine	P	The formation of a protein-protein cross-link between peptidyl-threonine and peptidyl-cysteine by the synthesis of (2S,3S,6R)-3-methyl-lanthionine (3-methyl-L-lanthionine).
18157	peptide cross-linking via an oxazole or thiazole	P	The chemical reactions and pathways resulting in the formation of a peptidyl serine-peptidyl glycine, or peptidyl cysteine-peptidyl glycine cross-link by the condensation of the serine hydroxyl or cysteine thiol with the carbonyl of the preceding residue and alpha-beta dehydrogenation.
18158	protein oxidation	P	The modification of a protein amino acid by oxidation.
18159	peptidyl-methionine oxidation	P	The oxidation of peptidyl-L-methionine to peptidyl-L-methionine sulfone.
18160	peptidyl-pyrromethane cofactor linkage	P	The covalent binding of a pyrromethane (dipyrrin) cofactor to protein via the sulfur atom of cysteine forming dipyrrolylmethanemethyl-L-cysteine.
18161	dipyrrin biosynthetic process	P	The chemical reactions and pathways resulting in the formation of dipyrrins (pyrromethanes), compounds containing two pyrrole rings linked through a methine, -CH=, group.
18162	peptide cross-linking via S-(2-aminovinyl)-3-methyl-D-cysteine	P	The formation of a cross-link between peptidyl-cysteine and peptidyl-threonine via the formation of S-(2-aminovinyl)-3-methyl-D-cysteine.
18163	protein-DNA covalent cross-linking via the 5'-end to peptidyl-tyrosine	P	The formation of a covalent cross-link between DNA and a peptidyl-tyrosine residue by the formation of O4'-(phospho-5'-DNA)-L-tyrosine.
18164	protein-DNA covalent cross-linking via peptidyl-threonine	P	The formation of a covalent cross-link between DNA and a peptidyl-threonine residue by the formation of O-(phospho-5'-DNA)-L-threonine.
18165	peptidyl-tyrosine uridylylation	P	The uridylylation of peptidyl-tyrosine to form peptidyl-O4'-(phospho-5'-uridine)-L-tyrosine, found in glutamine synthetase.
18166	C-terminal protein-tyrosinylation	P	The ATP-dependent addition of a tyrosine residue to the C-terminus of a protein; typically the addition of tyrosine to the C-terminus of detyrosinated alpha-tubulin by the enzyme tubulin-tyrosine ligase.
18167	protein-phycoerythrobilin linkage via phycoerythrobilin-bis-L-cysteine	P	The linkage of the chromophore phycoerythrobilin to phycoerythrin via phycoerythrobilin-bis-L-cysteine.
18168	protein-phycoerythrobilin linkage via S-phycoerythrobilin-L-cysteine	P	The linkage of the chromophore phycoerythrobilin to phycoerythrocyanin via S-phycoerythrobilin-L-cysteine.
18169	ribosomal S6-glutamic acid ligase activity	F	Catalysis of the posttranslational transfer of one or more glutamic acid residues to the C-terminus of ribosomal protein S6.
18170	C-terminal peptidyl-polyglutamic acid amidation	P	The formation of a C-terminal peptidyl-polyglutamic acid to form a peptidyl-N-L-glutamyl-poly-L-glutamic acid C-terminus.
18171	peptidyl-cysteine oxidation	P	The oxidation of peptidyl-cysteine to peptidyl-L-cysteine sulfinic acid or peptidyl-L-cysteine sulfenic acid.
18172	peptidyl-L-3',4',5'-trihydroxyphenylalanine biosynthetic process from peptidyl-tyrosine	P	The modification of protein tyrosine to peptidyl-L-3',4',5'-dihydroxyphenylalanine.
18173	peptidyl-1-thioglycine biosynthetic process from peptidyl-glycine	P	The chemical reactions and pathways resulting in the formation of peptidyl-1-thioglycine from other compounds, including peptidyl-glycine.
18174	protein-heme P460 linkage	P	The linkage of protein to heme P460.
18175	protein nucleotidylation	P	The addition of a nucleotide to a protein amino acid.
18177	protein uridylylation	P	The addition of phospho-uridine to a protein amino acid.
18178	peptidyl-threonine adenylylation	P	The adenylylation of peptidyl-threonine to form peptidyl-O-(phospho-5'-adenosine)-L-threonine.
18180	protein desulfurization	P	The removal of a sulfur group from a protein amino acid.
18181	peptidyl-arginine C5-methylation	P	The methylation of peptidyl-arginine on the carbon 5 (C5) residue to form peptidyl-5-methyl-L-arginine.
18182	protein-heme linkage via 3'-L-histidine	P	The covalent linkage of heme and a protein via 3'-L-histidine (otherwise known as pi-heme-histidine, pros-heme-histidine).
18184	protein polyamination	P	The modification of a protein amino acid by polyamination.
18185	poly-N-methyl-propylamination	P	The modification of peptidyl-lysine by the addition of an N6-propylamino and of propylmethylamino units, forming N6-(propylamino-poly(propylmethylamino)-propyldimethylamine)-L-lysine, typical of the silicate binding protein silaffin.
18186	peroxidase-heme linkage	P	The covalent linkage of heme to peroxidase.
18187	molybdenum incorporation via L-cysteinyl molybdopterin guanine dinucleotide	P	The incorporation of molybdenum into a protein by L-cysteinyl molybdopterin guanine dinucleotide.
18188	peptidyl-proline di-hydroxylation	P	The modification of peptidyl-proline to form trans-2,3-cis-3,4-dihydroxy-L-proline.
18189	pyrroloquinoline quinone biosynthetic process	P	The chemical reactions and pathways resulting in the formation of the cofactor pyrroloquinoline quinone (PQQ); it is synthesized from a small peptide containing tyrosine and glutamic acid; these amino acids in the peptide are multiply cross-linked and the rest of the peptide is removed.
18190	protein octanoylation	P	The modification of a protein amino acid by formation of an ester or amide with octanoic acid.
18191	peptidyl-serine octanoylation	P	The octanoylation of peptidyl-serine to form peptidyl-O3-octanoyl-L-serine, typical of the protein ghrelin.
18192	enzyme active site formation via cysteine modification to L-cysteine persulfide	P	The formation of an enzyme active site via modification of peptidyl-cysteine to peptidyl-L-cysteine persulfide.
18193	peptidyl-amino acid modification	P	The alteration of an amino acid residue in a peptide.
18194	peptidyl-alanine modification	P	The modification of peptidyl-alanine.
18195	peptidyl-arginine modification	P	The modification of peptidyl-arginine.
18196	peptidyl-asparagine modification	P	The modification of peptidyl-asparagine.
18197	peptidyl-aspartic acid modification	P	The modification of peptidyl-aspartic acid.
18198	peptidyl-cysteine modification	P	The modification of peptidyl-cysteine.
18199	peptidyl-glutamine modification	P	The modification of peptidyl-glutamine.
18200	peptidyl-glutamic acid modification	P	The modification of peptidyl-glutamic acid.
18201	peptidyl-glycine modification	P	The modification of peptidyl-glycine.
18202	peptidyl-histidine modification	P	The modification of peptidyl-histidine.
18203	peptidyl-isoleucine modification	P	The modification of peptidyl-isoleucine.
18204	peptidyl-leucine modification	P	The modification of peptidyl-leucine.
18205	peptidyl-lysine modification	P	The modification of peptidyl-lysine.
18206	peptidyl-methionine modification	P	The modification of peptidyl-methionine.
18207	peptidyl-phenylalanine modification	P	The modification of peptidyl-phenylalanine.
18208	peptidyl-proline modification	P	The modification of peptidyl-proline.
18209	peptidyl-serine modification	P	The modification of peptidyl-serine.
18210	peptidyl-threonine modification	P	The modification of peptidyl-threonine.
18211	peptidyl-tryptophan modification	P	The chemical alteration of a tryptophan residue in a peptide.
18212	peptidyl-tyrosine modification	P	The modification of peptidyl-tyrosine.
18213	peptidyl-valine modification	P	The modification of peptidyl-valine.
18214	protein carboxylation	P	The addition of a carboxy group to a protein amino acid.
18215	protein phosphopantetheinylation	P	The modification of a protein amino acid by phosphopantetheinylation.
18216	peptidyl-arginine methylation	P	The addition of a methyl group to an arginine residue in a protein.
18217	peptidyl-aspartic acid phosphorylation	P	The phosphorylation of peptidyl-aspartic acid.
18218	peptidyl-cysteine phosphorylation	P	The phosphorylation of peptidyl-cysteine to form peptidyl-S-phospho-L-cysteine.
18219	peptidyl-cysteine S-acetylation	P	The acetylation of peptidyl-cysteine to form peptidyl-S-acetyl-L-cysteine.
18220	peptidyl-threonine palmitoylation	P	The covalent attachment of a palmitoyl group to an oxygen (O) atom in a threonine residue to form peptidyl-O-palmitoyl-L-threonine.
18221	peptidyl-serine palmitoylation	P	The covalent attachment of a palmitoyl group to an oxygen (O) atom in a serine residue to form peptidyl-O-palmitoyl-L-serine.
18222	peptidyl-L-cysteine methyl disulfide biosynthetic process from peptidyl-cysteine	P	The modification of peptidyl-cysteine to form peptidyl-L-cysteine methyl disulfide.
18226	peptidyl-S-farnesyl-L-cysteine biosynthetic process from peptidyl-cysteine	P	The modification of peptidyl-cysteine to form peptidyl-S-farnesyl-L-cysteine; formation of S-farnesycysteine may be coupled with subsequent cleavage of a carboxy-terminal tripeptide for the CXXX motif and methyl esterification of the farnesylated cysteine; the residue may be found at the first position in the sequence motif C-X-X-(SAQCMT)* where the second and third positions are usually aliphatic.
18227	peptidyl-S-12-hydroxyfarnesyl-L-cysteine biosynthetic process from peptidyl-cysteine	P	The modification of peptidyl-cysteine to form S-12-hydroxyfarnesyl-L-cysteine; formation of S-farnesycysteine may be coupled with subsequent cleavage of a carboxy-terminal tripeptide for the CXXX motif and methyl esterification of the farnesylated cysteine.
18228	peptidyl-S-geranylgeranyl-L-cysteine biosynthetic process from peptidyl-cysteine	P	The modification of peptidyl-cysteine to form peptidyl-S-geranylgeranylcysteine; formation of S-geranylgeranyl-L-cysteine may be coupled with subsequent cleavage of a carboxy-terminal tripeptide for the CAAX motif and methyl esterification of the geranylgeranylated cysteine; methyl esterification but not cleavage occurs for the CXC motif. For the type II geranylgeranyltransferase the residue may be found at the first and final positions in the sequence motif C-X-C* or at the final position in the sequence motif C-C*. These motifs are necessary but not sufficient for modification.
18229	peptidyl-L-cysteine methyl ester biosynthetic process from peptidyl-cysteine	P	The modification of a C-terminal peptidyl-cysteine to form peptidyl-L-cysteine methyl ester.
18230	peptidyl-L-cysteine S-palmitoylation	P	The covalent attachment of a palmitoyl group to a sulfur (S) atom within a cysteine residue to form peptidyl-S-palmitoyl-L-cysteine.
18231	peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine	P	The modification of peptidyl-cysteine to form peptidyl-S-diacylglycerol-L-cysteine; the oleate and palmitate actually represent mixtures of saturated (generally at 3') and unsaturated (generally at 2') fatty acids.
18232	peptide cross-linking via S-(L-isoglutamyl)-L-cysteine	P	The modification of peptidyl-glutamine and peptidyl-cysteine to form a S-(L-isoglutamyl)-L-cysteine protein cross-link.
18233	peptide cross-linking via 2'-(S-L-cysteinyl)-L-histidine	P	The modification of peptidyl-histidine and peptidyl-cysteine to form a 2'-(S-L-cysteinyl)-L-histidine protein cross-link.
18234	peptide cross-linking via 3'-(S-L-cysteinyl)-L-tyrosine	P	The thioether cross-linking of a cysteine residue to a tyrosine residue to form 3'-(S-L-cysteinyl)-L-tyrosine, found in galactose oxidase.
18235	peptidyl-lysine carboxylation	P	The modification of peptidyl-lysine to form peptidyl-N6-carboxy-L-lysine.
18237	urease activator activity	F	Increases the activity of urease by promoting the incorporation of nickel into the active site.
18238	peptidyl-lysine carboxyethylation	P	The modification of peptidyl-lysine to form peptidyl-N6-1-carboxyethyl-L-lysine.
18240	protein S-linked glycosylation via cysteine	P	The glycosylation of protein via the sulfur atom of peptidyl-cysteine, forming S-glycosyl-L-cysteine.
18241	protein O-linked glycosylation via hydroxylysine	P	The glycosylation of protein via the O5 atom of peptidyl-hydroxylysine, forming O5-glycosyl-L-hydroxylysine; the most common form is galactosyl hydroxylysine.
18242	protein O-linked glycosylation via serine	P	The glycosylation of protein via the O3 atom of peptidyl-serine, forming O3-glycosyl-L-serine; the most common forms are N-acetylgalactosaminyl, mannosyl, galactosyl, and xylosyl serine.
18243	protein O-linked glycosylation via threonine	P	The glycosylation of protein via the O3 atom of peptidyl-threonine, forming O3-glycosyl-L-threonine; the most common forms are N-acetylgalactosaminyl, mannosyl, and galactosyl threonine.
18244	protein N-linked glycosylation via tryptophan	P	The glycosylation of protein via peptidyl-tryptophan, 1'-glycosyl-L-tryptophan; results in the formation of an (S)-2-amino-3-(1-D-mannopyranosyloxy-1H-indol-3-yl)propanoic acid residue.
18245	protein O-linked glycosylation via tyrosine	P	The glycosylation of protein via the O4' atom of peptidyl-tyrosine, O4'-glycosyl-L-tyrosine; the carbohydrate is glucose, the origin for glycogen.
18246	protein-coenzyme A linkage	P	The formation of a linkage between a protein amino acid and coenzyme A.
18247	protein-phosphoribosyl dephospho-coenzyme A linkage	P	The linkage of phosphoribosyl dephospho-coenzyme A to protein via peptidyl-serine, to form O-(phosphoribosyl dephospho-coenzyme A)-L-serine; it is uncertain whether the phosphoribosyl glycosidic attachment to the dephospho-coenzyme A is alpha or beta, and through the 2' or the 3' position.
18248	enzyme active site formation via peptidyl cysteine sulfation	P	The formation of an enzyme active site via transient sulfation of peptidyl-cysteine to form S-sulfo-L-cysteine.
18249	protein dehydration	P	The removal of a water group from a protein amino acid.
18250	peptidyl-dehydroalanine biosynthetic process from peptidyl-tyrosine or peptidyl-serine	P	The formation of peptidyl-dehydroalanine from either peptidyl-tyrosine by phenyl transfer, or from peptidyl-serine, which is coupled with the formation of 5-imidazolinone by the two neighboring residues, produces an 4-methylidene-imidazole-5-one active site of some amino acid ammonia-lyases; the 4-methylidene-imidazole-5-one, is formed autocatalytically by cyclization and dehydration of the sequence ASG.
18251	peptidyl-tyrosine dehydrogenation	P	The oxidation of the C alpha-C beta bond of peptidyl-tyrosine to form peptidyl-dehydrotyrosine coupled with cyclization of neighboring residues.
18252	peptide cross-linking via L-seryl-5-imidazolinone glycine	P	The formation of the green fluorescent protein chromophore cross-link from the alpha-carboxyl carbon of residue n, a serine, to the alpha-amino nitrogen of residue n+2, a glycine, and a dehydration to form a double bond to the alpha-amino nitrogen of residue n+1. This cross-linking is coupled with a dehydrogenation of residue n+1 to form a double bond between the alpha and beta carbons.
18253	peptide cross-linking via 5-imidazolinone glycine	P	The formation of a protein active site cross-link from the alpha-carboxyl carbon of residue n, an alanine, serine or cysteine, to the alpha-amino nitrogen of residue n+2, a glycine, and a dehydration to form a double bond to the alpha-amino nitrogen of residue n+1. This cross-linking is coupled with an oxidation of residue n+1 to form an active aldehyde.
18254	peptidyl-tyrosine adenylylation	P	The adenylylation of peptidyl-tyrosine to form peptidyl-O4'-(phospho-5'-adenosine)-L-tyrosine.
18255	peptide cross-linking via S-glycyl-L-cysteine	P	The formation of S-(peptidyl-glycyl)-peptidyl-cysteine cross-links by the formation of a thiolester between cysteine and the carboxy-terminal glycine of ubiquitin and other proteins.
18256	protein formylation	P	The addition of a formyl group to a protein amino acid.
18257	peptidyl-lysine formylation	P	The modification of peptidyl-lysine to form peptidyl-N6-formyl-L-lysine.
18258	protein O-linked glycosylation via hydroxyproline	P	The glycosylation of proteins via 04 atom of hydroxyproline to form O4-glycosyl-L-hydroxyproline; the most common form is arabinofuranosyl-4-proline.
18259	RNA-protein covalent cross-linking via peptidyl-serine	P	The formation of a covalent cross-link between RNA and a peptidyl-serine residue by the formation of O-(phospho-5'-5NA)-L-serine.
18260	protein guanylylation	P	The addition of phospho-guanosine to a protein amino acid.
18261	peptidyl-lysine guanylylation	P	The guanylylation of peptidyl-lysine to form peptidyl-N6-(phospho-5'-guanosine)-L-lysine.
18262	isopeptide cross-linking	P	The formation of a covalent cross-link between or within peptide chains, where either the amino group or the carboxyl group, or both, are not attached to the alpha carbon.
18263	isopeptide cross-linking via N-(L-isoaspartyl)-L-cysteine	P	The formation of an isopeptide cross-link between peptidyl-asparagine and peptidyl-cysteine to produce N-(L-isoaspartyl)-L-cysteine.
18264	isopeptide cross-linking via N-(L-isoaspartyl)-glycine	P	The formation of an isopeptide cross-link between peptidyl-asparagine and peptidyl-glycine to produce N-(L-isoaspartyl)-glycine.
18265	GPI anchor biosynthetic process via N-asparaginyl-glycosylphosphatidylinositolethanolamine	P	The chemical reactions and pathways resulting in the formation of a C-terminal peptidyl-asparagine ethanolamide-linked glycosylphosphatidylinositol (GPI) anchor following hydrolysis of a asparaginyl-peptide bond in the carboxy-terminal region of a membrane-associated protein.
18266	GPI anchor biosynthetic process via N-aspartyl-glycosylphosphatidylinositolethanolamine	P	The chemical reactions and pathways resulting in the formation of a C-terminal peptidyl-aspartic acid ethanolamide-linked glycosylphosphatidylinositol (GPI) anchor following hydrolysis of a aspartyl-peptide bond in the carboxy-terminal region of a membrane-associated protein.
18267	GPI anchor biosynthetic process via N-cysteinyl-glycosylphosphatidylinositolethanolamine	P	The chemical reactions and pathways resulting in the formation of a C-terminal peptidyl-cysteine ethanolamide-linked glycosylphosphatidylinositol (GPI) anchor following hydrolysis of a cysteinyl-peptide bond in the carboxy-terminal region of a membrane-associated protein.
18268	GPI anchor biosynthetic process via N-glycyl-glycosylphosphatidylinositolethanolamine	P	The chemical reactions and pathways resulting in the formation of a C-terminal peptidyl-glycine ethanolamide-linked glycosylphosphatidylinositol (GPI) anchor following hydrolysis of a glycyl-peptide bond in the carboxy-terminal region of a membrane-associated protein.
18269	GPI anchor biosynthetic process via N-seryl-glycosylphosphatidylinositolethanolamine	P	The chemical reactions and pathways resulting in the formation of a C-terminal peptidyl-serine ethanolamide-linked glycosylphosphatidylinositol (GPI) anchor following hydrolysis of a seryl-peptide bond in the carboxy-terminal region of a membrane-associated protein.
18270	GPI anchor biosynthetic process via N-alanyl-glycosylphosphatidylinositolethanolamine	P	The chemical reactions and pathways resulting in the formation of a C-terminal peptidyl-alanine ethanolamide-linked glycosylphosphatidylinositol (GPI) anchor following hydrolysis of an alanyl-peptide bond in the carboxy-terminal region of a membrane-associated protein.
18271	biotin-protein ligase activity	F	Catalysis of the reaction: ATP + biotin + protein = AMP + diphosphate + biotin-protein.
18272	protein-pyridoxal-5-phosphate linkage via peptidyl-N6-pyridoxal phosphate-L-lysine	P	The modification of peptidyl-lysine to form N6-pyridoxal phosphate-L-lysine.
18273	protein-chromophore linkage via peptidyl-N6-retinal-L-lysine	P	The modification of peptidyl-lysine to form N6-retinal-L-lysine.
18274	peptide cross-linking via L-lysinoalanine	P	The modification of peptidyl-lysine and peptidyl-serine to form a (2Xi,9S)-L-lysinoalanine cross-link.
18275	N-terminal peptidyl-cysteine acetylation	P	The acetylation of the N-terminal cysteine of proteins to form the derivative N-acetyl-L-cysteine.
18276	isopeptide cross-linking via N6-glycyl-L-lysine	P	The formation of an isopeptide cross-link between peptidyl-lysine and peptidyl-glycine to produce N6-glycyl-L-lysine. This is distinct from the formation of the thiolester intermediate, which occurs during ubiquitination.
18277	protein deamination	P	The removal of an amino group from a protein amino acid.
18278	N-terminal peptidyl-threonine deamination	P	The deamination of N-terminal peptidyl-threonine to form peptidyl-2-oxobutanoic acid.
18279	protein N-linked glycosylation via asparagine	P	The glycosylation of protein via the N4 atom of peptidyl-asparagine forming N4-glycosyl-L-asparagine; the most common form is N-acetylglucosaminyl asparagine; N-acetylgalactosaminyl asparagine and N4 glucosyl asparagine also occur. This modification typically occurs in extracellular peptides with an N-X-(ST) motif. Partial modification has been observed to occur with cysteine, rather than serine or threonine, in the third position; secondary structure features are important, and proline in the second or fourth positions inhibits modification.
18280	protein S-linked glycosylation	P	A protein glycosylation process in which a carbohydrate or carbohydrate derivative unit is added to a protein via a sulfur atom of a peptidyl-amino-acid such as cysteine or methionine.
18281	GSI anchor biosynthetic process via N-seryl-glycosylsphingolipidinositolethanolamine	P	The formation of a C-terminal peptidyl-serine ethanolamide-linked glycosylsphingolipidinositol (GSI) anchor following hydrolysis of a seryl-peptide bond in the carboxy-terminal region of a membrane-associated protein.
18282	metal incorporation into metallo-sulfur cluster	P	The formation of a cluster of several metal atoms, including iron, nickel, molybdenum, vanadium, or copper, with one or more bridging (mu-bond) sulfur atoms; amino acids residues in proteins that may ligate the metal sulfur cluster are cysteine, histidine, aspartate, glutamate, serine and cysteine persulfide.
18283	iron incorporation into metallo-sulfur cluster	P	The incorporation of iron into a metallo-sulfur cluster.
18284	iron incorporation into protein via tetrakis-L-cysteinyl iron	P	The incorporation of iron into a protein via tetrakis-L-cysteinyl iron (there is no exogenous sulfur, so this modification by itself does not produce an iron-sulfur protein).
18285	iron incorporation into iron-sulfur cluster via tetrakis-L-cysteinyl diiron disulfide	P	The incorporation of iron into a 2Fe-2S iron-sulfur cluster via tetrakis-L-cysteinyl diiron disulfide.
18287	iron incorporation into iron-sulfur cluster via tris-L-cysteinyl triiron tetrasulfide	P	The incorporation of iron into a 3Fe-4S iron-sulfur cluster via tris-L-cysteinyl triiron tetrasulfide.
18288	iron incorporation into iron-sulfur cluster via tetrakis-L-cysteinyl tetrairon tetrasulfide	P	The incorporation of iron into a 4Fe-4S iron-sulfur cluster via tetrakis-L-cysteinyl tetrairon tetrasulfide.
18289	molybdenum incorporation into metallo-sulfur cluster	P	The incorporation of molybdenum into a metallo-sulfur cluster.
18290	iron and molybdenum incorporation into iron-molybdenum-sulfur cluster via L-cysteinyl homocitryl molybdenum-heptairon-nonasulfide	P	The incorporation of iron and molybdenum into a Mo-7Fe-8S iron-molybdenum-sulfur cluster via L-cysteinyl homocitryl molybdenum-heptairon-nonasulfide, found in nitrogenase.
18291	molybdenum incorporation into iron-sulfur cluster	P	The incorporation of molybdenum into an iron-sulfur cluster.
18292	molybdenum incorporation via L-cysteinyl molybdopterin	P	The incorporation of molybdenum into a protein via L-cysteinyl molybdopterin.
18293	protein-FAD linkage	P	The formation of a linkage between a protein amino acid and flavin-adenine dinucleotide (FAD).
18294	protein-FAD linkage via S-(8alpha-FAD)-L-cysteine	P	The formation of a protein-FAD linkage via S-(8-alpha-FAD)-L-cysteine.
18295	protein-FAD linkage via 3'-(8alpha-FAD)-L-histidine	P	The formation of a protein-FAD linkage via 3'-(8-alpha-FAD)-L-histidine.
18296	protein-FAD linkage via O4'-(8alpha-FAD)-L-tyrosine	P	The formation of a protein-FAD linkage via O4'-(8-alpha-FAD)-L-tyrosine.
18297	protein-FAD linkage via 1'-(8alpha-FAD)-L-histidine	P	The formation of a protein-FAD linkage via 1'-(8-alpha-FAD)-L-histidine.
18298	protein-chromophore linkage	P	The covalent or noncovalent attachment of a chromophore to a protein.
18299	iron incorporation into the Rieske iron-sulfur cluster via bis-L-cysteinyl bis-L-histidino diiron disulfide	P	The incorporation of iron into a Rieske 4Fe-4S iron-sulfur cluster via bis-L-cysteinyl bis-L-histidino diiron disulfide.
18301	iron incorporation into iron-sulfur cluster via tris-L-cysteinyl-L-cysteine persulfido-bis-L-glutamato-L-histidino tetrairon	P	The incorporation of iron into an iron-sulfur cluster by tris-L-cysteinyl-L-cysteine persulfido-bis-L-glutamato-L-histidino tetrairon.
18302	iron incorporation into iron-sulfur cluster via tris-L-cysteinyl-L-N1'-histidino tetrairon tetrasulfide	P	The incorporation of iron into a 4Fe-4S iron-sulfur cluster via tris-L-cysteinyl-L-N1'-histidino tetrairon tetrasulfide.
18303	iron incorporation into iron-sulfur cluster via tris-L-cysteinyl-L-N3'-histidino tetrairon tetrasulfide	P	The incorporation of iron into a 4Fe-4S iron-sulfur cluster via tris-L-cysteinyl-L-N3'-histidino tetrairon tetrasulfide.
18304	iron incorporation into iron-sulfur cluster via tris-L-cysteinyl-L-aspartato tetrairon tetrasulfide	P	The incorporation of iron into a 4Fe-4S iron-sulfur cluster via tris-L-cysteinyl-L-aspartato tetrairon tetrasulfide.
18305	iron incorporation into iron-sulfur cluster via tris-L-cysteinyl-L-serinyl tetrairon tetrasulfide	P	The incorporation of iron into a 4Fe-4S iron-sulfur cluster via tris-L-cysteinyl-L-serinyl tetrairon tetrasulfide.
18306	iron incorporation into iron-sulfur cluster via bis-L-cysteinyl-L-N3'-histidino-L-serinyl tetrairon tetrasulfide	P	The incorporation of iron into a 4Fe-4S iron-sulfur cluster via bis-L-cysteinyl-L-N3'-histidino-L-serinyl tetrairon tetrasulfide.
18307	enzyme active site formation	P	The modification of part of an enzyme to form the active site.
18309	protein-FMN linkage	P	The formation of a linkage between a protein amino acid and flavin mononucleotide (FMN).
18310	protein-FMN linkage via S-(6-FMN)-L-cysteine	P	The formation of a protein-FMN linkage via S-(6-FMN)-L-cysteine.
18311	peptidyl-N4-hydroxymethyl-L-asparagine biosynthetic process from peptidyl-asparagine	P	The chemical reactions and pathways resulting in the formation of N4-hydroxymethyl-L-asparagine from other compounds, including peptidyl-asparagine.
18312	peptidyl-serine ADP-ribosylation	P	The transfer, from NAD, of ADP-ribose to peptidyl-serine to form peptidyl-O-(ADP-ribosyl)-L-serine.
18313	peptide cross-linking via L-alanyl-5-imidazolinone glycine	P	The formation of a protein active site cross-link from the alpha-carboxyl carbon of residue N, an alanine, to the alpha-amino nitrogen of residue N+2, a glycine, coupled with the formation of a double bond to the alpha-amino nitrogen of residue N+1 which loses one hydrogen, and the loss of a molecule of water.
18315	molybdenum incorporation into molybdenum-molybdopterin complex	P	The incorporation of molybdenum into a molybdenum-molybdopterin complex.
18316	peptide cross-linking via L-cystine	P	The oxidation of two peptidyl-cysteine residues to form a peptidyl-L-cystine (dicysteine) in which segments of peptide chain are linked by a disulfide bond; the cross-link may be between different or the same peptide chain.
18317	protein C-linked glycosylation via tryptophan	P	The glycosylation of a carbon atom of a peptidyl-tryptophan residue.
18320	enzyme active site formation via S-methyl-L-cysteine	P	The transient methylation of peptidyl-cysteine to form S-methyl-L-cysteine.
18321	protein glucuronylation	P	The modification of a protein by amino acid glucuronylation, the addition of a glucuronate group, the uronic acid derived from glucose.
18322	protein tyrosinylation	P	The addition of a tyrosine molecule to a protein amino acid.
18323	enzyme active site formation via L-cysteine sulfinic acid	P	The oxidation of peptidyl-cysteine to form peptidyl-L-cysteine sulfinic acid.
18324	enzyme active site formation via L-cysteine sulfenic acid	P	The oxidation of peptidyl-cysteine to form peptidyl-L-cysteine sulfenic acid, found in the active site of NADH peroxidase, nitrile hydratase, and peptide methionine sulfoxide reductase.
18325	enzyme active site formation via S-phospho-L-cysteine	P	The transient phosphorylation of peptidyl-cysteine to form S-phospho-L-cysteine.
18326	enzyme active site formation via S-acetyl-L-cysteine	P	The transient acetylation of peptidyl-cysteine to form S-acetyl-L-cysteine.
18327	enzyme active site formation via 1'-phospho-L-histidine	P	The transient phosphorylation of peptidyl-histidine to form 1'-phospho-L-histidine (otherwise known as tau-phosphohistidine, tele-phosphohistidine).
18328	enzyme active site formation via 3'-phospho-L-histidine	P	The transient phosphorylation of peptidyl-histidine to form 3'-phospho-L-histidine (otherwise known as pi-phosphohistidine, pros-phosphohistidine).
18329	enzyme active site formation via N6-(phospho-5'-adenosine)-L-lysine	P	The transient adenylylation of lysine to form N6-(phospho-5'-adenosine)-L-lysine, found in the active site of DNA ligase and RNA ligase.
18330	enzyme active site formation via N6-(phospho-5'-guanosine)-L-lysine	P	The transient guanylylation of lysine to form N6-(phospho-5'-guanosine)-L-lysine, found in the guanylyltransferase active site of mRNA capping enzyme.
18331	enzyme active site formation via O-phospho-L-serine	P	The transient phosphorylation of peptidyl-serine to form O-phospho-L-serine.
18332	enzyme active site formation via O-(phospho-5'-adenosine)-L-threonine	P	The transient adenylylation of threonine to form N6-(phospho-5'-adenosine)-L-threonine, found in the active site of bovine phosphodiesterase I.
18333	enzyme active site formation via O-phospho-L-threonine	P	The transient phosphorylation of peptidyl-threonine to form O-phospho-L-threonine.
18334	enzyme active site formation via O4'-phospho-L-tyrosine	P	The transient phosphorylation of peptidyl-tyrosine to form O-phospho-L-tyrosine.
18335	protein succinylation	P	The modification of a protein by the addition of a succinyl group (CO-CH2-CH2-CO) to an amino acid residue.
18336	peptidyl-tyrosine hydroxylation	P	The hydroxylation of peptidyl-tyrosine to form peptidyl-dihydroxyphenylalanine.
18339	peptidyl-L-beta-methylthioaspartic acid biosynthetic process from peptidyl-aspartic acid	P	The modification of peptidyl-aspartic acid to form peptidyl-L-beta-methylthioaspartic acid, typical of bacterial ribosomal protein S12.
18340	peptidyl-O-(sn-1-glycerophosphoryl)-L-serine biosynthetic process from peptidyl-serine	P	The modification of peptidyl-serine to peptidyl-O-(sn-1-glycerophosphoryl)-L-serine.
18341	peptidyl-lysine modification to peptidyl-N6-pyruvic acid 2-iminyl-L-lysine	P	The modification of peptidyl-lysine to form peptidyl-N6-pyruvic acid 2-iminyl-L-lysine.
18342	protein prenylation	P	The covalent attachment of a prenyl group to a protein; geranyl, farnesyl, or geranylgeranyl groups may be added.
18343	protein farnesylation	P	The covalent attachment of a farnesyl group to a protein.
18344	protein geranylgeranylation	P	The covalent attachment of a geranylgeranyl group to a protein.
18345	protein palmitoylation	P	The covalent attachment of a palmitoyl group to a protein.
18350	protein esterification	P	The addition of an ester group to a protein amino acid.
18351	peptidyl-cysteine esterification	P	The addition of an ester group to a cysteine residue in a protein.
18352	protein-pyridoxal-5-phosphate linkage	P	The formation of a linkage between a protein amino acid and pyridoxal-5-phosphate.
18353	protein-phycocyanobilin linkage via S-phycocyanobilin-L-cysteine	P	The linkage of the chromophore phycocyanobilin to phycocyanin or allophycocyanin via S-phycocyanobilin-L-cysteine.
18355	protein-phosphoribosyl dephospho-coenzyme A linkage via O-(phosphoribosyl dephospho-coenzyme A)-L-serine	P	The formation of a protein-phosphoribosyl dephospho-coenzyme A linkage via O-(phosphoribosyl dephospho-coenzyme A)-L-serine.
18356	protein-phycobiliviolin linkage via S-phycobiliviolin-L-cysteine	P	The linkage of the chromophore phycobiliviolin to phycoerythrocyanin via S-phycobiliviolin-L-cysteine.
18357	protein-phycourobilin linkage via phycourobilin-bis-L-cysteine	P	The linkage of the chromophore phycourobilin to phycoerythrins via phycourobilin-bis-L-cysteine.
18358	protein-phytochromobilin linkage via S-phytochromobilin-L-cysteine	P	The linkage of the chromophore phytochromobilin to phycocyanin or allophycocyanin via S-phytochromobilin-L-cysteine.
18359	protein-heme P460 linkage via heme P460-bis-L-cysteine-L-tyrosine	P	The linkage of protein to heme P460 via heme P460-bis-L-cysteine-L-tyrosine.
18360	protein-heme P460 linkage via heme P460-bis-L-cysteine-L-lysine	P	The linkage of protein to heme P460 via heme P460-bis-L-cysteine-L-lysine.
18361	peptidyl-glutamine 2-methylation	P	The methylation of glutamine to form 2-methyl-L-glutamine.
18362	peroxidase-heme linkage via dihydroxyheme-L-aspartyl ester-L-glutamyl ester	P	The covalent linkage of heme to peroxidase via dihydroxyheme-L-aspartyl ester-L-glutamyl ester.
18363	peroxidase-heme linkage via dihydroxyheme-L-aspartyl ester-L-glutamyl ester-L-methionine sulfonium	P	The covalent linkage of heme to peroxidase via dihydroxyheme-L-aspartyl ester-L-glutamyl ester-L-methionine sulfonium.
18364	peptidyl-glutamine methylation	P	The addition of a methyl group to a glutamine residue in a protein.
18365	protein-serine epimerase activity	F	Catalysis of the reaction: (protein)-L-serine = (protein)-D-serine.
18366	chiral amino acid racemization	P	The formation of a mixture of the two possible enantiomers from the D- or L-enantiomer of a chiral amino acid.
18376	peptidyl-asparagine hydroxylation to form L-erythro-beta-hydroxyasparagine	P	The hydroxylation of peptidyl-asparagine to form peptidyl-L-erythro-beta-hydroxyasparagine; catalyzed by peptide-aspartate beta-dioxygenase (EC:1.14.11.16).
18377	protein myristoylation	P	The covalent attachment of a myristoyl group to a protein.
18378	cytochrome c-heme linkage via heme-L-cysteine	P	The linkage of cytochromes and other heme proteins to heme via heme-L-cysteine.
18379	cytochrome c-heme linkage via heme-bis-L-cysteine	P	The linkage of cytochromes and other heme proteins to heme via heme-bis-L-cysteine.
18386	N-terminal peptidyl-cysteine condensation with pyruvate to form N-pyruvic acid 2-iminyl-L-cysteine	P	The condensation of pyruvate through the 2-oxo group with the N-terminal cysteine of proteins to form the derivative N-pyruvic acid 2-iminyl-L-cysteine.
18387	N-terminal peptidyl-amino acid deamination to pyruvic acid	P	The oxidative deamination of N-terminal peptidyl-cysteine, or peptidyl-serine, to form pyruvic acid with an amide bond between its 1-carboxyl group and the N-terminal residue.
18388	N-terminal peptidyl-valine condensation with pyruvate to form N-pyruvic acid 2-iminyl-L-valine	P	The condensation of pyruvate through the 2-oxo group with the N-terminal valine of proteins to form the derivative N-pyruvic acid 2-iminyl-L-valine.
18389	N-terminal peptidyl-valine deamination	P	The deamination of the N-terminal valine residue of a protein to form isobutyrate.
18390	peptidyl-L-glutamic acid 5-methyl ester biosynthetic process from peptidyl-glutamic acid or peptidyl-glutamine	P	The methyl esterification of peptidyl-glutamic acid or peptidyl-glutamine to form the derivative glutamic acid 5-methyl ester.
18391	C-terminal peptidyl-glutamic acid tyrosinylation	P	The ATP-dependent addition of a tyrosine residue to a glutamic acid residue at the C-terminus of a protein.
18392	glycoprotein 3-alpha-L-fucosyltransferase activity	F	Catalysis of the reaction: N(4)-{N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->6)]-beta-D-mannosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-N-acetyl-beta-D-glucosaminyl}-L-asparagine + GDP-L-fucose = N(4)-{N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->6)]-beta-D-mannosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-[alpha-L-fucosyl-(1->3)]-N-acetyl-beta-D-glucosaminyl}-L-asparagine + GDP + H(+).
18393	internal peptidyl-lysine acetylation	P	The addition of an acetyl group to a non-terminal lysine residue in a protein.
18394	peptidyl-lysine acetylation	P	The acetylation of peptidyl-lysine.
18395	peptidyl-lysine hydroxylation to 5-hydroxy-L-lysine	P	The hydroxylation of peptidyl-lysine to peptidyl-5-hydroxy-L-lysine.
18396	peptidyl-lysine hydroxylation to 4-hydroxy-L-lysine	P	The hydroxylation of peptidyl-lysine to peptidyl-4-hydroxy-L-lysine.
18397	peptidyl-phenylalanine bromination to L-2'-bromophenylalanine	P	The bromination of peptidyl-phenylalanine to form L-2'-bromophenylalanine.
18398	peptidyl-phenylalanine bromination to L-3'-bromophenylalanine	P	The bromination of peptidyl-phenylalanine to form L-3'-bromophenylalanine.
18399	peptidyl-phenylalanine bromination to L-4'-bromophenylalanine	P	The bromination of peptidyl-phenylalanine to form L-4'-bromophenylalanine.
18400	peptidyl-proline hydroxylation to 3-hydroxy-L-proline	P	The modification of peptidyl-proline to form 3-hydroxy-L-proline; catalyzed by procollagen-proline 3-dioxygenase.
18401	peptidyl-proline hydroxylation to 4-hydroxy-L-proline	P	The modification of peptidyl-proline to form 4-hydroxy-L-proline; catalyzed by procollagen-proline,2-oxoglutarate-4-dioxygenase.
18402	protein-chondroitin sulfate linkage via chondroitin sulfate D-glucuronyl-D-galactosyl-D-galactosyl-D-xylosyl-L-serine	P	Chondroitin sulfate components are covalently linked to a core glycoprotein via O-glycosidic linkages between xylose and serine residues.
18403	protein-dermatan sulfate linkage via dermatan 4-sulfate D-glucuronyl-D-galactosyl-D-galactosyl-D-xylosyl-L-serine	P	Dermatan sulfate components are covalently linked to a core glycoprotein via O-glycosidic linkages between xylose and serine residues.
18404	protein-heparan sulfate linkage via heparan sulfate D-glucuronyl-D-galactosyl-D-galactosyl-D-xylosyl-L-serine	P	Heparan sulfate components are covalently linked to a core glycoprotein via O-glycosidic linkages between xylose and serine residues.
18405	protein-keratan sulfate linkage via keratan sulfate D-glucuronyl-D-galactosyl-D-galactosyl-D-xylosyl-L-threonine	P	Keratan sulfate components are covalently linked to a core glycoprotein via O-glycosidic linkages between xylose and threonine residues.
18406	protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan	P	The glycosylation of a peptidyl-tryptophan residue by the transfer of alpha-mannopyranose from dolichyl-activated mannose to the indole ring.
18407	peptidyl-thyronine iodination to form 3',3'',5'-triiodo-L-thyronine	P	The iodination of peptidyl-thyronine to form peptidyl-3',3'',5'-triiodo-L-thyronine (triiodothyronine).
18408	peptidyl-thyronine iodination to form 3',3'',5',5''-tetraiodo-L-thyronine	P	The iodination of peptidyl-thyronine to form peptidyl-3',3'',5',5''-tetraiodo-L-thyronine (L-thyroxine).
18410	C-terminal protein amino acid modification	P	The alteration of the C-terminal amino acid residue in a protein.
18411	protein glucuronidation	P	The modification of a protein by amino acid glucuronidation.
18412	protein O-glucuronidation	P	The modification of a protein by glucuronidation on an amino acid oxygen atom.
18413	peptidyl-serine O-glucuronidation	P	The O-glucuronidation of peptidyl-serine to form peptidyl-O3-D-glucuronyl-L-serine.
18414	nickel incorporation into metallo-sulfur cluster	P	The incorporation of nickel into a metallo-sulfur cluster.
18415	iron incorporation into iron-sulfur cluster via tris-L-cysteinyl L-cysteine persulfido bis-L-glutamato L-histidino nickel triiron disulfide trioxide	P	The incorporation of iron into a 3Fe-2S cluster via tris-L-cysteinyl L-cysteine persulfido bis-L-glutamato L-histidino nickel triiron disulfide trioxide.
18416	nickel incorporation into iron-sulfur cluster via tris-L-cysteinyl L-cysteine persulfido bis-L-glutamato L-histidino nickel triiron disulfide trioxide	P	The incorporation of nickel into a 3Fe-2S complex by tris-L-cysteinyl L-cysteine persulfido bis-L-glutamato L-histidino nickel triiron disulfide trioxide.
18417	iron incorporation into iron-sulfur cluster via tris-L-cysteinyl L-cysteine persulfido L-glutamato L-histidino L-serinyl nickel triiron disulfide trioxide	P	The incorporation of iron into a 3Fe-2S cluster by tris-L-cysteinyl L-cysteine persulfido L-glutamato L-histidino L-serinyl nickel triiron disulfide trioxide.
18418	nickel incorporation into iron-sulfur cluster via tris-L-cysteinyl L-cysteine persulfido L-glutamato L-histidino L-serinyl nickel triiron disulfide trioxide	P	The incorporation of nickel into a 3Fe-2S complex by tris-L-cysteinyl L-cysteine persulfido L-glutamato L-histidino L-serinyl nickel triiron disulfide trioxide.
18419	protein catenane formation	P	The aggregation, arrangement and bonding together of a protein structure comprising two or more rings that are interlocked but not covalently joined; resembling the links of a chain.
18420	peptide cross-linking via N6-(L-isoaspartyl)-L-lysine	P	The formation of isopeptide bonds by ligation of peptidyl-lysine and peptidyl-asparagine residues.
18421	UDP-N-acetylglucosamine:serine-protein N-acetylglucosamine-1-phosphotransferase activity	F	Catalysis of the transfer of N-acetylglucosamine-1-phosphate to a serine residue in a protein.
18422	GDP-mannose:serine-protein mannose-1-phosphotransferase activity	F	Catalysis of the transfer of mannose-1-phosphate to a serine residue in a protein.
18423	protein C-terminal leucine carboxyl O-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + protein L-leucine = S-adenosyl-L-homocysteine + protein L-leucine methyl ester. This modification occurs only at the oxygen atoms of the free alpha carboxyl group of a leucine residue at the C-terminus of the protein.
18424	peptidyl-glutamic acid poly-ADP-ribosylation	P	This modification produces peptidyl-glutamic acid poly-ADP-ribose found in a number of nuclear proteins under certain conditions including the repair of single strand DNA breaks. The activated form of the generating enzyme poly(ADP-ribose) polymerase is itself modified in this way.
18425	O3-(N-acetylglucosamine-1-phosphoryl)-L-serine biosynthetic process	P	The chemical reactions and pathways resulting in the formation of O3-(N-acetylglucosamine-1-phosphoryl)-L-serine. The recovery of O-phosphorylserine from acid hydrolysates suggests N-acetylglucosamine-1-phosphate residues are esterified to peptidyl serines through phosphoester bonds.
18426	O3-(phosphoglycosyl-D-mannose-1-phosphoryl)-L-serine biosynthetic process	P	The chemical reactions and pathways resulting in the formation of O3-(phosphoglycosyl-D-mannose-1-phosphoryl)-L-serine. The polypeptide backbones of glycoproteins and mucin-like proteoglycans are extensively modified with a complex array of phosphoglycan chains that are linked to Ser/Thr-rich domains via a common Man-alpha1-PO4-Ser linkage.
18427	copper incorporation into metallo-sulfur cluster	P	The incorporation of copper into a metallo-sulfur cluster.
18428	copper incorporation into copper-sulfur cluster	P	The incorporation of copper into a copper-sulfur cluster.
18429	copper incorporation into copper-sulfur cluster via heptakis-L-histidino tetracopper mu4-sulfide hydroxide	P	The incorporation of copper into a 4Cu-S copper-sulfur cluster via heptakis-L-histidino tetracopper mu4-sulfide hydroxide.
18439	peptidyl-L-leucine methyl ester biosynthetic process from peptidyl-leucine	P	The modification of a C-terminal peptidyl-leucine to form peptidyl-L-leucine methyl ester.
18441	iron incorporation into iron-sulfur cluster via hexakis-L-cysteinyl L-serinyl octairon heptasulfide	P	The incorporation of iron into a 8Fe-7S iron-sulfur cluster via hexakis-L-cysteinyl L-serinyl octairon heptasulfide, found in nitrogenase.
18442	peptidyl-glutamic acid esterification	P	The addition of an ester group to a glutamic acid residue in a protein.
18443	enzyme active site formation via L-aspartic 4-phosphoric anhydride	P	The transient phosphorylation of peptidyl-aspartic acid to form L-aspartic 4-phosphoric anhydride.
18444	translation release factor complex	C	A heterodimeric complex involved in the release of a nascent polypeptide chain from a ribosome.
18445	prothoracicotrophic hormone activity	F	The action characteristic of prothoracicotrophic hormone, a peptide hormone that is secreted by the brain and, upon receptor binding, acts on the prothoracic gland to stimulate the release of ecdysone in insects.
18446	pinocarveol dehydrogenase activity	F	Catalysis of the reaction: pinocarveol = pinocarvone + 2 H+ + 2 e-.
18447	chloral hydrate dehydrogenase activity	F	Catalysis of the reactions: chloral hydrate = 3 H+ + 2 e- + trichloroacetate, and chloral hydrate + H2 = H2O + trichloroethanol.
18448	hydroxymethylmethylsilanediol oxidase activity	F	Catalysis of the reaction: hydroxymethylmethylsilanediol + O2 + 2 H+ + 2 e- = formylmethylsilanediol + 2 H2O.
18449	1-phenylethanol dehydrogenase activity	F	Catalysis of the reaction: (S)-1-phenylethanol = acetophenone + H2.
18450	myrtenol dehydrogenase activity	F	Catalysis of the reaction: myrtenol + O2 + 2 H+ + 2 e- = 2 H2O + myrtenal.
18451	epoxide dehydrogenase activity	F	Catalysis of the reaction: ethene oxide + NAD+ + CoA-SH = NADH + H+ + acetyl-CoA.
18452	5-exo-hydroxycamphor dehydrogenase activity	F	Catalysis of the reaction: 5-exo-hydroxycamphor + NAD+ = NADH + H+ + 2,5-diketocamphane.
18453	2-hydroxytetrahydrofuran dehydrogenase activity	F	Catalysis of the reaction: 2-hydroxytetrahydrofuran = 2 H+ + 2 e- + butyrolactone.
18454	acetoacetyl-CoA reductase activity	F	Catalysis of the reaction: (R)-3-hydroxyacyl-CoA + NADP+ = 3-oxoacyl-CoA + NADPH + H+.
18455	alcohol dehydrogenase [NAD(P)+] activity	F	Catalysis of the reaction: an alcohol + NAD(P)+ = an aldehyde + NAD(P)H + H+.
18456	aryl-alcohol dehydrogenase (NAD+) activity	F	Catalysis of the reaction: an aromatic alcohol + NAD+ = an aromatic aldehyde + NADH + H+.
18457	perillyl-alcohol dehydrogenase activity	F	Catalysis of the reaction: NAD(+) + perillyl alcohol = H(+) + NADH + perillyl aldehyde.
18458	isopiperitenol dehydrogenase activity	F	Catalysis of the reaction: (1S,6R)-isopiperitenol + NAD(+) = (6R)-isoperitenone + H(+) + NADH.
18459	carveol dehydrogenase activity	F	Catalysis of the reaction: (1S,5R)-carveol + NADP(+) = (R)-carvone + H(+) + NADPH.
18460	cyclohexanol dehydrogenase activity	F	Catalysis of the reaction: cyclohexanol + NAD+ = cyclohexanone + NADH + H+.
18461	fluoren-9-ol dehydrogenase activity	F	Catalysis of the reaction: fluoren-9-ol + 2 NADP+ = fluoren-9-one + 2 NADPH + 2 H+.
18462	4-(hydroxymethyl)benzenesulfonate dehydrogenase activity	F	Catalysis of the reaction: 4-(hydroxymethyl)benzenesulfonate + NAD(+) = 4-formylbenzenesulfonate + H(+) + NADH.
18463	6-hydroxyhexanoate dehydrogenase activity	F	Catalysis of the reaction: 6-hydroxyhexanoate + NAD(+) = 6-oxohexanoate + H(+) + NADH.
18464	3-hydroxypimeloyl-CoA dehydrogenase activity	F	Catalysis of the reaction: 3-hydroxypimelyl-CoA + NAD(+) = 3-oxopimelyl-CoA + H(+) + NADH.
18465	vanillyl-alcohol oxidase activity	F	Catalysis of the reaction: O(2) + vanillyl alcohol = H(2)O(2) + vanillin.
18466	limonene-1,2-diol dehydrogenase activity	F	Catalysis of the reaction: (1S,2S,4R)-limonene-1,2-diol + DCPIP+ = DCPIPH + H+ + (1S,4R)-1-hydroxy-2-oxolimonene.
18467	formaldehyde dehydrogenase activity	F	Catalysis of the reaction: formaldehyde + H(2)O + NAD(+) = formate + 2 H(+) + NADH.
18468	alcohol dehydrogenase (acceptor) activity	F	Catalysis of the reaction: a primary alcohol + acceptor = an aldehyde + reduced acceptor.
18469	myrtenal dehydrogenase activity	F	Catalysis of the reaction: myrtenal + H2O = 2 H+ + 2 e- + myrtenic acid.
18470	4-hydroxybutaraldehyde dehydrogenase activity	F	Catalysis of the reaction: 4-hydroxybutyraldehyde + H2O = 2 H+ + 2 e- + 4-hydroxybutanoate.
18471	4-chlorobenzaldehyde oxidase activity	F	Catalysis of the reaction: 4-chlorobenzaldehyde + 2 H2O = 4-chlorobenzoate + 2 H+ + 2 e-.
18472	1-hydroxy-2-naphthaldehyde dehydrogenase activity	F	Catalysis of the reaction: 1-hydroxy-2-naphthaldehyde + NAD+ + H2O = NADH + H+ + 1-hydroxy-2-naphthoate.
18473	cis-2-methyl-5-isopropylhexa-2,5-dienal dehydrogenase activity	F	Catalysis of the reaction: cis-2-methyl-5-isopropylhexa-2,5-dienal + NAD+ + H2O = NADH + H+ + cis-2-methyl-5-isopropylhexa-2,5-dienoic acid.
18474	2-carboxybenzaldehyde dehydrogenase activity	F	Catalysis of the reaction: 2-carboxybenzaldehyde + NAD+ + H2O = NADH + 2 H+ + phthalate.
18475	trans-2-methyl-5-isopropylhexa-2,5-dienal dehydrogenase activity	F	Catalysis of the reaction: trans-2-methyl-5-isopropylhexa-2,5-dienal + NAD+ + H2O = NADH + H+ + trans-2-methyl-5-isopropylhexa-2,5-dienoic acid.
18477	benzaldehyde dehydrogenase (NADP+) activity	F	Catalysis of the reaction: benzaldehyde + NADP+ + H2O = benzoate + NADPH + H+.
18478	malonate-semialdehyde dehydrogenase (acetylating) activity	F	Catalysis of the reaction: 3-oxopropanoate + CoA + NADP+ = acetyl-CoA + CO2 + NADPH + H+.
18479	benzaldehyde dehydrogenase (NAD+) activity	F	Catalysis of the reaction: benzaldehyde + NAD+ + H2O = benzoate + NADH + H+.
18480	5-carboxymethyl-2-hydroxymuconic-semialdehyde dehydrogenase activity	F	Catalysis of the reaction: 5-carboxymethyl-2-hydroxymuconate semialdehyde + H2O + NAD+ = 5-carboxymethyl-2-hydroxymuconate + NADH + H+.
18481	4-hydroxymuconic-semialdehyde dehydrogenase activity	F	Catalysis of the reaction: <stereo>cis,trans</stereo>-4-hydroxymuconate semialdehyde + H(2)O + NAD(+) = 2 H(+) + maleylacetate + NADH.
18482	4-formylbenzenesulfonate dehydrogenase activity	F	Catalysis of the reaction: 4-formylbenzenesulfonate + H(2)O + NAD(+) = 4-sulfobenzoate + 2 H(+) + NADH.
18483	6-oxohexanoate dehydrogenase activity	F	Catalysis of the reaction: 6-oxohexanoate + NADP+ + H2O = adipate + NADPH + H+.
18484	4-hydroxybenzaldehyde dehydrogenase activity	F	Catalysis of the reaction: 4-hydroxybenzaldehyde + NAD+ + H2O = 4-hydroxybenzoate + NADH + H+.
18485	salicylaldehyde dehydrogenase activity	F	Catalysis of the reaction: salicylaldehyde + NAD+ + H2O = salicylate + NADH + H+.
18486	2-butanone oxidase activity	F	Catalysis of the reaction: methyl ethyl ketone + O2 = H2O + ethyl acetate.
18487	vanillate O-demethylase (anaerobic) activity	F	Catalysis of the reaction: vanillate + Co+ = Co3+-CH3 + 3,4-dihydroxybenzoate.
18488	aryl-aldehyde oxidase activity	F	Catalysis of the reaction: an aromatic aldehyde + O2 + H2O = an aromatic acid + hydrogen peroxide.
18489	vanillate monooxygenase activity	F	Catalysis of the reaction: H(+) + NADH + O(2) + vanillate = 3,4-dihydroxybenzoate + formaldehyde + H(2)O + NAD(+).
18490	4-hydroxyphenylpyruvate oxidase activity	F	Catalysis of the reaction: 2 (4-hydroxyphenyl)pyruvate + O(2) = 2 (4-hydroxyphenyl)acetate + 2 CO(2).
18491	2-oxobutyrate synthase activity	F	Catalysis of the reaction: 2-oxobutanoate + CoA + oxidized ferredoxin = propanoyl-CoA + CO2 + reduced ferredoxin.
18492	carbon-monoxide dehydrogenase (acceptor) activity	F	Catalysis of the reaction: CO + H2O + acceptor = CO2 + reduced acceptor.
18493	formylmethanofuran dehydrogenase activity	F	Catalysis of the reaction: N-formylmethanofuran + A + H(2)O + H(+) = AH(2) + CO(2) + methanofuran.
18494	carvone reductase activity	F	Catalysis of the reaction: carvone + 2 H+ + 2 e- = dihydrocarvone.
18495	2-hydroxycyclohexane-1-carboxyl-CoA dehydrogenase activity	F	Catalysis of the reaction: 2-hydroxycyclohexane-1-carboxyl-CoA = 2 H+ + 2 e- + 2-ketocyclohexane-1-carboxyl-CoA.
18496	2,6-dihydroxycyclohexane-1-carboxyl-CoA dehydrogenase activity	F	Catalysis of the reaction: 2,6-dihydroxycyclohexane-1-carboxyl-CoA = 2 H+ + 2 e- + 6-oxo-2-hydroxycyclohexane-1-carboxyl-CoA.
18497	1-chloro-2,2-bis(4-chlorophenyl)ethane dehydrogenase activity	F	Catalysis of the reaction: 1-chloro-2,2-bis(4-chlorophenyl)ethene + 2 H+ + 2 e- = 1-chloro-2,2-bis(4-chlorophenyl)ethane. 1-chloro-2,2-bis(4-chlorophenyl)ethene is also known as DDMU; 1-chloro-2,2-bis(4-chlorophenyl)ethane is also known as DDMS.
18498	2,3-dihydroxy-2,3-dihydro-phenylpropionate dehydrogenase activity	F	Catalysis of the reaction: cis-3-(3-carboxyethyl)-3,5-cyclohexadiene-1,2-diol + NAD+ = NADH + H+ + 3-(2,3-dihydroxyphenyl)propionate.
18499	cis-2,3-dihydrodiol DDT dehydrogenase activity	F	Catalysis of the reaction: cis-2,3-dihydrodiol DDT + NADP+ = NADPH + 2,3-dihydroxy DDT.
18500	trans-9R,10R-dihydrodiolphenanthrene dehydrogenase activity	F	Catalysis of the reaction: trans-9R,10R-dihydrodiolphenanthrene + NAD+ = NADH + H+ + 9,10-dihydroxyphenanthrene.
18501	cis-chlorobenzene dihydrodiol dehydrogenase activity	F	Catalysis of the conversion of a di- or tetrachlorinated dienol to the corresponding catechol.
18502	2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase activity	F	Catalysis of the reaction: 2,5-dichloro-2,5-cyclohexadiene-1,4-diol + NAD+ = NADH + H+ + 2,5-dichlorohydroquinone.
18503	trans-1,2-dihydrodiolphenanthrene dehydrogenase activity	F	Catalysis of the reaction: trans-1,2-dihydrodiolphenanthrene + NAD+ = H+ + NADH + 1,2-dihydroxyphenanthrene.
18504	cis-1,2-dihydrobenzene-1,2-diol dehydrogenase activity	F	Catalysis of the reaction: cis-1,2-dihydrobenzene-1,2-diol + NAD+ = catechol + NADH + H+.
18505	cis-1,2-dihydro-1,2-dihydroxynaphthalene dehydrogenase activity	F	Catalysis of the reaction: cis-1,2-dihydronaphthalene-1,2-diol + NAD+ = naphthalene-1,2-diol + NADH + H+.
18506	maleylacetate reductase activity	F	Catalysis of the reaction: 3-oxoadipate + NAD(P)+ = 2-maleylacetate + NAD(P)H + H+.
18507	cis-3,4-dihydrophenanthrene-3,4-diol dehydrogenase activity	F	Catalysis of the reaction: (3S,4R)-3,4-dihydrophenanthrene-3,4-diol + NAD(+) = H(+) + NADH + phenanthrene-3,4-diol.
18508	cis-1,2-dihydroxycyclohexa-3,5-diene-1-carboxylate dehydrogenase activity	F	Catalysis of the reaction: cis-1,2-dihydroxycyclohexa-3,5-diene-1-carboxylate + NAD+ = catechol + CO2 + NADH + H+.
18509	cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase activity	F	Catalysis of the reaction: cis-3-phenylcyclohexa-3,5-diene-1,2-diol + NAD+ = biphenyl-2,3-diol + NADH + H+.
18510	phloroglucinol reductase activity	F	Catalysis of the reaction: dihydrophloroglucinol + NADP(+) = H(+) + NADPH + phloroglucinol.
18511	2,3-dihydroxy-2,3-dihydro-p-cumate dehydrogenase activity	F	Catalysis of the reaction: cis-2,3-dihydroxy-2,3-dihydro-p-cumate + NAD(+) = 2,3-dihydroxy-p-cumate + H(+) + NADH.
18513	dibenzothiophene dihydrodiol dehydrogenase activity	F	Catalysis of the reaction: cis-1,2-dihydroxy-1,2-dihydrodibenzothiophene + NAD(+) = 1,2-dihydroxydibenzothiophene + H(+) + NADH.
18515	pimeloyl-CoA dehydrogenase activity	F	Catalysis of the reaction: NAD(+) + pimelyl-CoA = 2,3-didehydropimeloyl-CoA + H(+) + NADH.
18516	2,4-dichlorobenzoyl-CoA reductase activity	F	Catalysis of the reaction: 4-chlorobenzoyl-CoA + chloride + NADP(+) = 2,4-dichlorobenzoyl-CoA + NADPH.
18517	phthalate 4,5-cis-dihydrodiol dehydrogenase activity	F	Catalysis of the reaction: cis-4,5-dihydroxycyclohexa-2,6-diene-1,2-dicarboxylate + NAD(+) = 4,5-dihydroxyphthalate + H(+) + NADH.
18518	5,6-dihydroxy-3-methyl-2-oxo-1,2,5,6-tetrahydroquinoline dehydrogenase activity	F	Catalysis of the reaction: 5,6-dihydroxy-3-methyl-5,6-dihydroquinolin-2(1H)-one + NAD(+) = 5,6-dihydroxy-3-methyl-2-oxo-1,2-dihydroquinoline + H(+) + NADH.
18519	cis-dihydroethylcatechol dehydrogenase activity	F	Catalysis of the reaction: cis-1,2-dihydro-3-ethylcatechol + NAD(+) = 3-ethylcatechol + H(+) + NADH.
18520	cis-1,2-dihydroxy-4-methylcyclohexa-3,5-diene-1-carboxylate dehydrogenase activity	F	Catalysis of the reaction: cis-1,2-dihydroxy-4-methylcyclohexa-3,5-diene-1-carboxylate + NADP+ = 4-methylcatechol + NADPH + H+ + CO2.
18521	1,2-dihydroxy-6-methylcyclohexa-3,5-dienecarboxylate dehydrogenase activity	F	Catalysis of the reaction: 1,6-dihydroxy-2-methylcyclohexa-2,4-dienecarboxylate + NAD(+) = 3-methylcatechol + CO(2) + NADH.
18522	benzoyl-CoA reductase activity	F	Catalysis of the reaction: 2 ADP + cyclohexa-1,5-diene-1-carbonyl-CoA + oxidized ferredoxin + 2 phosphate = 2 ATP + 2 H(2)O + benzoyl-CoA + reduced ferredoxin.
18523	quinoline 2-oxidoreductase activity	F	Catalysis of the reaction: quinoline + acceptor + H2O = isoquinolin-1(2H)-one + reduced acceptor.
18524	acetophenone carboxylase activity	F	Catalysis of the reaction: acetophenone + CO2 = H+ + benzoyl acetate.
18525	4-hydroxybenzoyl-CoA reductase activity	F	Catalysis of the reaction: benzoyl-CoA + oxidized ferredoxin + H2O = 4-hydroxybenzoyl-CoA + reduced ferredoxin.
18526	2-aminobenzoyl-CoA reductase activity	F	Catalysis of the reaction: 2-aminobenzoyl-CoA + 2 H+ + 2 e- = NH3 + benzoyl-CoA.
18527	cyclohexylamine oxidase activity	F	Catalysis of the reaction: cyclohexylamine + O2 + H2O = cyclohexanone + NH3 + hydrogen peroxide.
18528	iminodiacetate dehydrogenase activity	F	Catalysis of the reaction: iminodiacetate + OH- = H+ + 2 e- + glyoxylate + glycine.
18529	nitrilotriacetate monooxygenase activity	F	Catalysis of the reaction: nitrilotriacetate + NADH + H+ + O2 = NAD+ + H2O + glyoxylate + iminodiacetate.
18530	(R)-6-hydroxynicotine oxidase activity	F	Catalysis of the reaction: (R)-6-hydroxynicotine + H(2)O + O(2) = 6-hydroxypseudooxynicotine + H(2)O(2).
18531	(S)-6-hydroxynicotine oxidase activity	F	Catalysis of the reaction: (S)-6-hydroxynicotine + H(2)O + O(2) = 6-hydroxypseudooxynicotine + H(2)O(2).
18532	5,10-methenyl-5,6,7,8-tetrahydromethanopterin dehydrogenase activity	F	Catalysis of the reaction: N5,N10-methenyltetrahydromethanopterin + H2 = N5,N10-methylenetetrahydromethanopterin.
18533	peptidyl-cysteine acetylation	P	The acetylation of peptidyl-cysteine.
18534	nitrilotriacetate dehydrogenase activity	F	Catalysis of the reaction: nitrilotriacetate + OH- = H+ + 2 e- + glyoxylate + iminodiacetate.
18535	nicotine dehydrogenase activity	F	Catalysis of the reaction: nicotine + acceptor + H2O = (S)-6-hydroxynicotine + reduced acceptor.
18537	coenzyme F420-dependent N5,N10-methenyltetrahydromethanopterin reductase activity	F	Catalysis of the reaction: 5-methyltetrahydromethanopterin + coenzyme F420 + H(+) = 5,10-methylenetetrahydromethanopterin + reduced coenzyme F420.
18538	epoxide carboxylase activity	F	Catalysis of the generic reaction: epoxide + CO2 + NAD+ + electron donor = beta-keto acid + NADH + reduced electron donor; the electron donor may be NADPH or a dithiol. This reaction is the ring opening and carboxylation of an epoxide; for example: epoxypropane + CO2 + NAD+ + NADPH = acetoacetate + NADH + NADP+.
18541	p-benzoquinone reductase (NADPH) activity	F	Catalysis of the reaction: 1,4-benzoquinone + H(+) + NADPH = hydroquinone + NADP(+).
18542	2,3-dihydroxy DDT 1,2-dioxygenase activity	F	Catalysis of the reaction: 2,3-dihydroxy DDT + O2 = 6-oxo-2-hydroxy-7-(4-chlorophenyl)-3,8,8,8-tetrachloroocta-2E,4E-dienoate.
18543	4-amino-2-nitroso-6-nitrotoluene reductase activity	F	Catalysis of the reaction: 4-amino-2-hydroxylamino-6-nitrotoluene + NADP+ = NADPH + H+ + 4-amino-2-nitroso-6-nitrotoluene.
18544	4-carboxy-4'-sulfoazobenzene reductase activity	F	Catalysis of the reaction: 4-carboxy-4'-sulfoazobenzene + 4 H+ + 4 e- = 4-aminobenzoate + 4-aminobenzenesulfonate.
18545	NAD(P)H nitroreductase activity	F	Catalysis of the conversion of a nitrate group to an amino or hydroxylamino group on toluene or a toluene derivative.
18546	nitrobenzene nitroreductase activity	F	Catalysis of the reaction: nitrobenzene + 2 NADPH + 2 H+ = hydroxyaminobenzene + 2 NADP+ + H2O.
18547	nitroglycerin reductase activity	F	Catalysis of the removal of one or more nitrite (NO2-) groups from nitroglycerin or a derivative.
18548	pentaerythritol trinitrate reductase activity	F	Catalysis of the reaction: pentaerythritol trinitrate + NADPH = NADP+ + nitrate + pentaerythritol dinitrate.
18549	methanethiol oxidase activity	F	Catalysis of the reaction: methanethiol + O2 + H2O = formaldehyde + hydrogen sulfide + hydrogen peroxide.
18550	tetrachloro-p-hydroquinone reductive dehalogenase activity	F	Catalysis of the reaction: 2,3,5,6-tetrachlorohydroquinone + 2 glutathione = 2,3,6-trichlorohydroquinone + glutathione disulfide + HCl.
18551	hydrogensulfite reductase activity	F	Catalysis of the reaction: trithionate + acceptor + 2 H2O + OH- = 3 HSO3- + reduced acceptor.
18553	3-(2,3-dihydroxyphenyl)propionate 1,2-dioxygenase activity	F	Catalysis of the reaction: 3-(2,3-dihydroxyphenyl)propionate + O2 = 2-hydroxy-6-keto-nona-2,4-dienedioate.
18554	1,2-dihydroxynaphthalene dioxygenase activity	F	Catalysis of the reaction: 1,2-dihydroxynaphthalene + O2 = 2-hydroxychromene-2-carboxylate. C6 of the substrate molecular may have an NH2 group attached.
18555	phenanthrene dioxygenase activity	F	Catalysis of the reaction: phenanthrene + NADH + H+ + O2 = NAD+ + cis-3,4-dihydroxy-3,4-dihydrophenanthrene.
18556	2,2',3-trihydroxybiphenyl dioxygenase activity	F	Catalysis of the reaction: 2,3-dihydroxybenzenoid + O2 = H+ + distal extradiol ring cleavage. Substrates are 2,2',3-trihydroxybiphenyl (forms 2-hydroxy-6-oxo-6-(2-hydroxyphenyl)-hexa-2,4-dienoate) and 2,2',3-trihydroxydiphenylether (forms 2,3-hydroxy-6-oxo-6-(2-hydroxyphenyl)-hexa-2,4-dienoate).
18557	1,2-dihydroxyfluorene 1,1-alpha-dioxygenase activity	F	Catalysis of the reaction: 1,2-dihydroxyfluorene + O2 = 2-hydroxy-4-(2-oxo-1,3-dihydro-2H-inden-1-ylidene) but-2-enoic acid.
18558	5,6-dihydroxy-3-methyl-2-oxo-1,2-dihydroquinoline dioxygenase activity	F	Catalysis of the reaction: 5,6-dihydroxy-3-methyl-2-oxo-1,2-dihydroquinoline + O2 = 3-methyl-5-hydroxy-6-(3-carboxy-3-oxopropenyl)-1H-2-pyridon.
18559	1,1-dichloro-2-(dihydroxy-4-chlorophenyl)-(4-chlorophenyl)ethene 1,2-dioxygenase activity	F	Catalysis of the reaction: 1,1-dichloro-2-(dihydroxy-4'-chorophenyl)-2-(4-chlorophenyl)ethene + O2 = 6-oxo-2-hydroxy-7-(4-chlorophenyl)-3,8,8-trichloroocta-2E,4E,7-trienoate.
18560	protocatechuate 3,4-dioxygenase type II activity	F	Catalysis of the reaction: 4-sulfocatechol + O2 = 3-sulfomuconate.
18561	2'-aminobiphenyl-2,3-diol 1,2-dioxygenase activity	F	Catalysis of the reaction: 2'-aminobiphenyl-2,3-diol + O2 = H+ + 2-hydroxy-6-oxo-(2'-aminophenyl)-hexa-2,4-dienoate.
18562	3,4-dihydroxyfluorene 4,4-alpha-dioxygenase activity	F	Catalysis of the reaction: 3,4-dihydroxyfluorene + O2 = 2-hydroxy-4-(1-oxo-1,3-dihydro-2H-inden-2-ylidene) but-2-enoic acid.
18563	2,3-dihydroxy-ethylbenzene 1,2-dioxygenase activity	F	Catalysis of the reaction: 2,3-dihydroxyethylbenzene + O2 = H+ + 2-hydroxy-6-oxoocta-2,4-dienoate.
18564	carbazole 1,9a-dioxygenase activity	F	Catalysis of the reaction: carbazole + NADH + O2 + H+ = NAD+ + 2'-aminobiphenyl-2,3-diol.
18565	dihydroxydibenzothiophene dioxygenase activity	F	Catalysis of the reaction: 1,2-dihydroxydibenzothiophene + O2 = cis-4-(2-(3-hydroxy)-thionaphthenyl)-2-oxo-3-butenoate.
18566	1,2-dihydroxynaphthalene-6-sulfonate 1,8a-dioxygenase activity	F	Catalysis of the reaction: 1,2-dihydroxynaphthalene-6-sulfonate + O2 = H+ + (Z)-4-(2-hydroxy-5-sulfonatophenyl)-2-oxo-3-butenoate.
18567	styrene dioxygenase activity	F	Catalysis of the reaction: styrene + O2 + NADH + H+ = NAD+ + styrene cis-glycol.
18568	3,4-dihydroxyphenanthrene dioxygenase activity	F	Catalysis of the reaction: 3,4-dihydroxyphenanthrene + O2 = H+ + 2-hydroxy-2 H-benzo[h]chromene-2-carboxylate.
18569	hydroquinone 1,2-dioxygenase activity	F	Catalysis of the reaction: hydroquinone + O2 = cis,trans-4-hydroxymuconic semialdehyde.
18570	p-cumate 2,3-dioxygenase activity	F	Catalysis of the reaction: p-cumate + NADH + H+ + O2 = NAD+ + cis-2,3-dihydroxy-2,3-dihydro-p-cumate.
18571	2,3-dihydroxy-p-cumate dioxygenase activity	F	Catalysis of the reaction: 2,3-dihydroxy-p-cumate + O2 = 2-hydroxy-3-carboxy-6-oxo-7-methylocta-2,4-dienoate.
18572	3,5-dichlorocatechol 1,2-dioxygenase activity	F	Catalysis of the reaction: 3,5-dichlorocatechol + O2 = 2 H+ + 2,4-dichloro-cis,cis-muconate.
18573	2-aminophenol 1,6-dioxygenase activity	F	Catalysis of the reaction: 2-aminophenol + O2 = 2-aminomuconic semialdehyde.
18574	2,6-dichloro-p-hydroquinone 1,2-dioxygenase activity	F	Catalysis of the reaction: 2,6-dichlorohydroquinone + O2 + H2O = HCl + 2 H+ + 2-chloromaleylacetate.
18575	chlorocatechol 1,2-dioxygenase activity	F	Catalysis of the reaction: 3,6-dichlorocatechol + O2 = 2 H+ + 2,5-dichloro-cis,cis-muconate.
18576	catechol 1,2-dioxygenase activity	F	Catalysis of the reaction: catechol + O2 = cis,cis-muconate.
18577	catechol 2,3-dioxygenase activity	F	Catalysis of the reaction: catechol + O2 = 2-hydroxymuconate semialdehyde.
18578	protocatechuate 3,4-dioxygenase activity	F	Catalysis of the reaction: 3,4-dihydroxybenzoate + O2 = 3-carboxy-cis,cis-muconate.
18579	protocatechuate 4,5-dioxygenase activity	F	Catalysis of the reaction: protocatechuate + O2 = 4-carboxy-2-hydroxymuconate semialdehyde.
18580	nitronate monooxygenase activity	F	Catalysis of the reaction: ethylnitronate + O(2) = acetaldehyde + nitrite.
18581	hydroxyquinol 1,2-dioxygenase activity	F	Catalysis of the reaction: benzene-1,2,4-triol + O2 = 3-hydroxy-cis,cis-muconate.
18582	1-hydroxy-2-naphthoate 1,2-dioxygenase activity	F	Catalysis of the reaction: 1-hydroxy-2-naphthoate + O2 = (3E)-4-(2-carboxyphenyl)-2-oxobut-3-enoate.
18583	biphenyl-2,3-diol 1,2-dioxygenase activity	F	Catalysis of the reaction: biphenyl-2,3-diol + O2 = 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate + H2O.
18584	2,4,5-trichlorophenoxyacetic acid oxygenase activity	F	Catalysis of the reaction: 2,4,5-trichlorophenoxyacetic acid + 1/2 O2 = glyoxylate + 2,4,5-trichlorophenol.
18585	fluorene oxygenase activity	F	Catalysis of the reaction: fluorene + 2 H+ + 2 e- + O2 = H2O + 9-fluorenol.
18586	mono-butyltin dioxygenase activity	F	Catalysis of the reaction: butyltin + O2 + 2 H+ + 2 e- = H2O + beta-hydroxybutyltin.
18588	tri-n-butyltin dioxygenase activity	F	Catalysis of the reaction: tri-n-butyltin + O2 + 2 H+ + 2 e- = H2O + beta-hydroxybutyldibutyltin.
18589	di-n-butyltin dioxygenase activity	F	Catalysis of the reaction: dibutyltin + O2 + 2 H+ + 2 e- = H2O + beta-hydroxybutylbutyltin.
18590	methylsilanetriol hydroxylase activity	F	Catalysis of the reaction: methylsilanetriol + O2 + 2 H+ + 2 e- = H2O + hydroxymethylsilanetriol.
18591	methyl tertiary butyl ether 3-monooxygenase activity	F	Catalysis of the reaction: methyl tert-butyl ether + 1/2 O2 = tert-butyl alcohol + formaldehyde.
18592	4-nitrocatechol 4-monooxygenase activity	F	Catalysis of the reaction: 4-nitrocatechol + O2 + 4 e- + 3 H+ = H2O + nitrite + 1,2,4-benzenetriol.
18593	4-chlorophenoxyacetate monooxygenase activity	F	Catalysis of the reaction: 4-chlorophenoxyacetate + 1/2 O2 = glyoxylate + 4-chlorophenol.
18594	tert-butanol 2-monooxygenase activity	F	Catalysis of the reaction: tert-butanol + 1/2 O2 = 2-methyl-2-hydroxy-1-propanol.
18595	alpha-pinene monooxygenase activity	F	Catalysis of the reaction: alpha-pinene + O2 + 2 H+ + 2 e- = H2O + pinocarveol.
18596	dimethylsilanediol hydroxylase activity	F	Catalysis of the reaction: dimethylsilanediol + O2 + 2 H+ + 2 e- = H2O + hydroxymethylmethylsilanediol.
18597	ammonia monooxygenase activity	F	Catalysis of the oxidation of alkanes (up to C8) to alcohols and alkenes (up to C5) to epoxides and alcohols in the presence of ammonium ions.
18598	hydroxymethylsilanetriol oxidase activity	F	Catalysis of the reaction: hydroxymethylsilanetriol + O2 + 2 H+ + 2 e- = 2 H2O + formylsilanetriol.
18599	2-hydroxyisobutyrate 3-monooxygenase activity	F	Catalysis of the reaction: 2-hydroxyisobutyrate + 1/2 O2 = 2,3-dihydroxy-2-methyl propionate.
18600	alpha-pinene dehydrogenase activity	F	Catalysis of the reaction: alpha-pinene + O2 + 2 H+ + 2 e- = H2O + myrtenol.
18601	4-nitrophenol 2-monooxygenase activity	F	Catalysis of the reaction: 4-nitrophenol + H(+) + NADH + O(2) = 4-nitrocatechol + H(2)O + NAD(+).
18602	2,4-dichlorophenoxyacetate alpha-ketoglutarate dioxygenase activity	F	Catalysis of the reaction: 2,4-dichlorophenoxyacetate + 2-oxoglutarate + oxygen = 2,4-dichlorophenol + glyoxylate + succinate + CO2.
18603	nitrobenzene 1,2-dioxygenase activity	F	Catalysis of the reaction: nitrobenzene + NADH + O2 = NAD+ + nitrite + catechol.
18604	4-aminobenzoate 3,4-dioxygenase (deaminating) activity	F	Catalysis of the reaction: 4-aminobenzoate + 2 H+ + O2 + 2 e- = NH3 + 3,4-dihydroxybenzoate.
18606	benzenesulfonate dioxygenase activity	F	Catalysis of the reaction: toluene-4-sulfonate + NADH + O2 + H+ = NAD+ + HSO3(-) + 4-methylcatechol.
18607	1-indanone monooxygenase activity	F	Catalysis of the reaction: 1-indanone + NADPH + 1/2 O2 = NADP+ + 3,4-dihydrocoumarin.
18608	1-indanone dioxygenase activity	F	Catalysis of the reaction: 1-indanone + NADPH + 1/2 O2 = NADP+ + 3-hydroxy-1-indanone.
18609	chlorobenzene dioxygenase activity	F	Catalysis of the reaction: 2,3-unsubstituted benzenoid + O2 + NAD(P)H + H+ = 2,3-cis-dihydroxydihydrobenzenoid + NAD(P)+. Substrates include 1,4-dichlorobenzene (forms 3,6-dichloro-cis-1,2-dihydroxycyclohexa-3,5-diene), 1,2,3,4-tetrachlorobenzene (forms cis-chlorobenzene dihydrodiol) and 1,2,4-trichlorobenzene (forms 3,4,6-trichloro-cis-1,2-dihydroxycyclohexa-3,5-diene).
18610	dibenzofuran 4,4a-dioxygenase activity	F	Catalysis of the reaction: dibenzofuran + NADH + H+ + O2 = 2,2',3-trihydroxybiphenyl + NAD+.
18611	toluate dioxygenase activity	F	Catalysis of the reaction: methylbenzoate + NADH + O2 + H+ = NAD+ + 1,2-dihydroxymethylcyclohexa-3,5-dienecarboxylate.
18612	dibenzothiophene dioxygenase activity	F	Catalysis of the reaction: dibenzothiophene + NADH + O2 + H+ = NAD+ + cis-1,2-dihydroxy-1,2-dihydrodibenzothiophene.
18613	9-fluorenone dioxygenase activity	F	Catalysis of the reaction: 9-fluorenone + 2 NADPH + O2 = 2 NADP+ + 3,4-dihydroxy-3,4-dihydro-9-fluorenone.
18614	ethylbenzene dioxygenase activity	F	Catalysis of the reaction: ethylbenzene + O2 + NADH + H+ = NAD+ + cis-2,3-dihydroxy-2,3-dihydroethylbenzene.
18615	2-indanone monooxygenase activity	F	Catalysis of the reaction: 2-indanone + NADPH + 1/2 O2 = NADP+ + 3-isochromanone.
18616	trihydroxytoluene dioxygenase activity	F	Catalysis of the reaction: 2,3,5-trihydroxytoluene + O2 = 2,4,6-trioxoheptanoate.
18617	4-aminobenzenesulfonate 3,4-dioxygenase (deaminating) activity	F	Catalysis of the reaction: 4-aminobenzenesulfonate + 2 H+ + O2 + 2 e- = NH3 + 4-sulfocatechol.
18618	anthranilate 1,2-dioxygenase (deaminating, decarboxylating) activity	F	Catalysis of the reaction: anthranilate + NADPH + H+ + O2 = catechol + CO2 + NADP+ + NH3.
18619	benzene 1,2-dioxygenase activity	F	Catalysis of the reaction: benzene + H(+) + NADH + O(2) = cis-cyclohexa-3,5-diene-1,2-diol + NAD(+).
18620	phthalate 4,5-dioxygenase activity	F	Catalysis of the reaction: H(+) + NADH + O(2) + phthalate = cis-4,5-dihydroxycyclohexa-2,6-diene-1,2-dicarboxylate + NAD(+).
18621	4-sulfobenzoate 3,4-dioxygenase activity	F	Catalysis of the reaction: 4-sulfobenzoate + H(+) + NADH + O(2) = 3,4-dihydroxybenzoate + NAD(+) + sulfite.
18622	4-chlorophenylacetate 3,4-dioxygenase activity	F	Catalysis of the reaction: 4-chlorophenylacetate + NADH + O(2) = 3,4-dihydroxyphenylacetate + chloride + NAD(+).
18623	benzoate 1,2-dioxygenase activity	F	Catalysis of the reaction: benzoate + NADH + H+ + O2 = catechol + CO2 + NAD+.
18624	toluene dioxygenase activity	F	Catalysis of the reaction: H(+) + NADH + O(2) + toluene = (1S,2R)-3-methylcyclohexa-3,5-diene-1,2-diol + NAD(+).
18625	naphthalene 1,2-dioxygenase activity	F	Catalysis of the reaction: naphthalene + NADH + H+ + O2 = (1R,2S)-1,2-dihydronaphthalene-1,2-diol + NAD+.
18626	2-chlorobenzoate 1,2-dioxygenase activity	F	Catalysis of the reaction: 2-chlorobenzoate + NADH + H+ + O2 = catechol + chloride + NAD+ + CO2.
18627	2-aminobenzenesulfonate 2,3-dioxygenase activity	F	Catalysis of the reaction: 2-aminobenzenesulfonate + 2 H(+) + NADH + O(2) = 2,3-dihydroxybenzenesulfonate + NAD(+) + NH(4)(+). 2,3-dihydroxybenzenesulfonate is also known as 3-sulfocatechol.
18628	terephthalate 1,2-dioxygenase activity	F	Catalysis of the reaction: H(+) + NADH + O(2) + terephthalate = (3S,4R)-3,4-dihydroxycyclohexa-1,5-diene-1,4-dicarboxylate + NAD(+).
18629	2-hydroxyquinoline 5,6-dioxygenase activity	F	Catalysis of the reaction: quinolin-2-ol + NADH + H+ + O2 = 2,5,6-trihydroxy-5,6-dihydroquinoline + NAD+.
18630	3,5-xylenol methylhydroxylase activity	F	Catalysis of the reaction: 3-hydroxytoluene + NADH + O2 = NAD+ + OH- + 3-hydroxybenzyl alcohol.
18631	phenylacetate hydroxylase activity	F	Catalysis of the reaction: phenylacetate + NADH + O2 = NAD+ + OH- + 2-hydroxyphenylacetate.
18632	4-nitrophenol 4-monooxygenase activity	F	Catalysis of the reaction: p-nitrophenol + O2 + NADPH = H2O + NADP+ + nitrite + p-benzoquinone.
18633	dimethyl sulfide monooxygenase activity	F	Catalysis of the reaction: dimethyl sulfide + NADH + O2 = NAD+ + OH- + methanethiol + formaldehyde.
18634	alpha-pinene monooxygenase [NADH] activity	F	Catalysis of the reaction: alpha-pinene + NADH + H+ + O2 = NAD+ + H2O + alpha-pinene oxide.
18635	(R)-limonene 1,2-monooxygenase activity	F	Catalysis of the reaction: (4R)-limonene + NAD(P)H + H+ + O2 = NAD(P)+ + H2O + (4R)-limonene-1,2-epoxide.
18636	phenanthrene 9,10-monooxygenase activity	F	Catalysis of the reaction: phenanthrene + O2 + NADH + H+ = H2O + NAD+ + phenanthrene-9,10-oxide.
18637	1-hydroxy-2-naphthoate hydroxylase activity	F	Catalysis of the reaction: 1-hydroxy-2-naphthoate + O2 + NADPH + 2 H+ = NADP+ + H2O + CO2 + 1,2-dihydroxynaphthalene.
18638	toluene 4-monooxygenase activity	F	Catalysis of the reaction: toluene + 1/2 O2 = 4-hydroxytoluene.
18639	xylene monooxygenase activity	F	Catalysis of the reactions: toluene + 1/2 O2 = benzyl alcohol, and xylene + 1/2 O2 = methylbenzyl alcohol.
18640	dibenzothiophene monooxygenase activity	F	Catalysis of the reaction: dibenzothiophene + NADH + H+ + O2 = dibenzothiophene-5-oxide + NAD+ + H2O.
18641	6-hydroxy-3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity	F	Catalysis of the reaction: 6-hydroxy-3-methyl-2-oxo-1,2-dihydroquinoline + O2 + 2 H+ + 2 e- = H2O + 5,6-dihydroxy-3-methyl-2-oxo-1,2-dihydroquinoline.
18642	chlorophenol 4-monooxygenase activity	F	Catalysis of the addition or substitution of an OH group on C4 of a halogenated phenol.
18643	carbon disulfide oxygenase activity	F	Catalysis of the reaction: carbon disulfide + NADH + H+ + O2 = [S] + H2O + NAD+ + carbonyl sulfide.
18644	toluene 2-monooxygenase activity	F	Catalysis of the reaction: toluene + 1/2 O2 = 2-hydroxytoluene.
18645	alkene monooxygenase activity	F	Catalysis of the reaction: propene + NADH + H+ + O2 = 1,2-epoxypropane + NAD+ + H2O.
18646	1-hydroxy-2-oxolimonene 1,2-monooxygenase activity	F	Catalysis of the reaction: (1S,4R)-1-hydroxy-2-oxolimonene + NADPH + O2 = NADP+ + OH- + (3R)-3-isopropenyl-6-oxoheptanoate.
18647	phenanthrene 1,2-monooxygenase activity	F	Catalysis of the reaction: phenanthrene + O2 + NADH + H+ = H2O + NAD+ + phenanthrene-1,2-oxide.
18648	methanesulfonate monooxygenase activity	F	Catalysis of the reaction: methanesulfonate + NADH + H+ + O2 = formaldehyde + NAD+ + sulfite + H2O.
18649	tetrahydrofuran hydroxylase activity	F	Catalysis of the reaction: tetrahydrofuran + O2 + 2 H+ + 2 e- = H2O + 2-hydroxytetrahydrofuran.
18650	styrene monooxygenase activity	F	Catalysis of the reaction: styrene + NADPH + FADH + O2 = NADP+ + FAD+ + H2O + styrene oxide.
18651	toluene-4-sulfonate monooxygenase activity	F	Catalysis of the reaction: toluene-4-sulfonate + 1/2 O2 + H+ = HSO3(-) + 4-hydroxytoluene.
18652	toluene-sulfonate methyl-monooxygenase activity	F	Catalysis of the reaction: toluene-4-sulfonate + NADH + O2 = NAD+ + OH- + 4-sulfobenzyl alcohol.
18653	3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity	F	Catalysis of the reaction: 3-methyl-2-oxo-1,2-dihydroquinoline + O2 + 2 H+ + 2 e- = H2O + 6-hydroxy-3-methyl-2-oxo-1,2-dihydroquinoline.
18654	2-hydroxy-phenylacetate hydroxylase activity	F	Catalysis of the reaction: 2-hydroxyphenylacetate + NADH + O2 = NAD+ + OH- + homogentisate.
18655	2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA 1,2-monooxygenase activity	F	Catalysis of the reaction: 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA + NADH + H+ + O2 = NAD+ + H2O + delta2,5-3,4,4-trimethylpimelyl-CoA.
18656	phenanthrene 3,4-monooxygenase activity	F	Catalysis of the reaction: phenanthrene + O2 + NADH + H+ = H2O + NAD+ + phenanthrene-3,4-oxide.
18657	toluene 3-monooxygenase activity	F	Catalysis of the reaction: toluene + 1/2 O2 = 3-hydroxytoluene.
18658	salicylate 1-monooxygenase activity	F	Catalysis of the reaction: salicylate + NADH + H+ + O2 = catechol + NAD+ + H2O + CO2.
18659	4-hydroxybenzoate 3-monooxygenase activity	F	Catalysis of the reaction: 4-hydroxybenzoate + NADPH + H+ + O2 = protocatechuate + NADP+ + H2O.
18660	4-hydroxyphenylacetate,NADH:oxygen oxidoreductase (3-hydroxylating) activity	F	Catalysis of the reaction: 4-hydroxyphenylacetate + NADH + H+ + O2 = 3,4-dihydroxyphenylacetate + NAD+ + H2O.
18661	orcinol 2-monooxygenase activity	F	Catalysis of the reaction: H(+) + NADH + O(2) + orcinol = 2,3,5-trihydroxytoluene + H(2)O + NAD(+).
18662	phenol 2-monooxygenase activity	F	Catalysis of the reaction: phenol + NADPH + H+ + O2 = catechol + NADP+ + H2O.
18663	2,6-dihydroxypyridine 3-monooxygenase activity	F	Catalysis of the reaction: 2,6-dihydroxypyridine + H(+) + NADH + O(2) = 2,3,6-trihydroxypyridine + H(2)O + NAD(+).
18664	benzoate 4-monooxygenase activity	F	Catalysis of the reaction: benzoate + H(+) + NADPH + O(2) = 4-hydroxybenzoate + H(2)O + NADP(+).
18665	4-hydroxyphenylacetate 1-monooxygenase activity	F	Catalysis of the reaction: 4-hydroxyphenylacetate + NADPH + H+ + O2 = homogentisate + NADP+ + H2O.
18666	2,4-dichlorophenol 6-monooxygenase activity	F	Catalysis of the reaction: 2,4-dichlorophenol + NADPH + H+ + O2 = 3,5-dichlorocatechol + NADP+ + H2O.
18667	cyclohexanone monooxygenase activity	F	Catalysis of the reaction: cyclohexanone + NADPH + H+ + O2 = 6-hexanolide + NADP+ + H2O.
18668	3-hydroxybenzoate 4-monooxygenase activity	F	Catalysis of the reaction: 3-hydroxybenzoate + H(+) + NADPH + O(2) = 3,4-dihydroxybenzoate + H(2)O + NADP(+).
18669	3-hydroxybenzoate 6-monooxygenase activity	F	Catalysis of the reaction: 3-hydroxybenzoate + H(+) + NADH + O(2) = 2,5-dihydroxybenzoate + H(2)O + NAD(+).
18670	4-aminobenzoate 1-monooxygenase activity	F	Catalysis of the reaction: 4-aminobenzoate + NADPH + H+ + O2 = 4-hydroxyaniline + NADP+ + H2O + CO2.
18671	4-hydroxybenzoate 3-monooxygenase [NAD(P)H] activity	F	Catalysis of the reaction: 4-hydroxybenzoate + NAD(P)H + H+ + O2 = 3,4-dihydroxybenzoate + NAD(P)+ + H2O.
18672	anthranilate 3-monooxygenase (deaminating) activity	F	Catalysis of the reaction: anthranilate + 2 H(+) + NADPH + O(2) = 2,3-dihydroxybenzoate + NADP(+) + NH(4)(+).
18673	anthraniloyl-CoA monooxygenase activity	F	Catalysis of the reaction: 2-aminobenzoyl-CoA + 2 NADPH + 2 H+ + O2 = 2-amino-5-oxocyclohex-1-enecarboxyl-CoA + H2O + 2 NADP+.
18674	(S)-limonene 3-monooxygenase activity	F	Catalysis of the reaction: (4S)-limonene + H(+) + NADPH + O(2) = (1S,6R)-isopiperitenol + H(2)O + NADP(+).
18675	(S)-limonene 6-monooxygenase activity	F	Catalysis of the reaction: (-)-limonene + NADPH + H+ + O2 = (-)-trans-carveol + NADP+ + H2O.
18676	(S)-limonene 7-monooxygenase activity	F	Catalysis of the reaction: (4S)-limonene + H(+) + NADPH + O(2) = (4S)-perillyl alcohol + H(2)O + NADP(+).
18677	pentachlorophenol monooxygenase activity	F	Catalysis of the reaction: pentachlorophenol + NADPH + H+ + O2 = tetrachlorohydroquinone + NADP+ + chloride.
18678	4-hydroxybenzoate 1-hydroxylase activity	F	Catalysis of the reaction: 4-hydroxybenzoate + NADPH + H+ + O2 = hydroquinone + NADP+ + H2O + CO2.
18679	dibenzothiophene-5,5-dioxide monooxygenase activity	F	Catalysis of the reaction: dibenzothiophene-5,5-dioxide + O2 + 2 NADH + H+ = 2 NAD+ + H2O + 2'-hydroxybiphenyl-2-sulfinate.
18680	deethylatrazine monooxygenase activity	F	Catalysis of the reaction: 2 deethylatrazine + O2 = 2 CH3COCH3 + 2 deisopropyldeethylatrazine.
18681	deisopropylatrazine monooxygenase activity	F	Catalysis of the reaction: 2 deisopropylatrazine + O2 = 2 acetaldehyde + 2 deisopropyldeethylatrazine.
18682	atrazine N-dealkylase activity	F	Catalysis of the reaction: atrazine + O2 + 2 H+ = deethylatrazine + acetaldehyde + H2O.
18683	camphor 5-monooxygenase activity	F	Catalysis of the reaction: (+)-camphor + putidaredoxin + O2 = (+)-exo-5-hydroxycamphor + oxidized putidaredoxin + H2O.
18684	camphor 1,2-monooxygenase activity	F	Catalysis of the reaction: (1R)-bornane-2,5-dione + reduced rubredoxin + O2 = 5-oxo-1,2-campholide + oxidized rubredoxin + H2O.
18685	alkane 1-monooxygenase activity	F	Catalysis of the reaction: octane + reduced rubredoxin + O2 = 1-octanol + oxidized rubredoxin + H2O.
18686	6-hydroxy pseudo-oxynicotine monooxygenase activity	F	Catalysis of the reaction: 2 6-hydroxypseudooxynicotine + O2 = 2 2,6-dihydroxypseudooxynicotine.
18687	biphenyl 2,3-dioxygenase activity	F	Catalysis of the reaction: biphenyl + NADH + H+ + O2 = (2R,3S)-3-phenylcyclohexa-3,5-diene-1,2-diol + NAD+. This reaction requires Fe2+.
18688	DDT 2,3-dioxygenase activity	F	Catalysis of the reaction: 1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane + O2 + 2 H+ + 2 e- = cis-2,3-dihydrodiol DDT. 1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane is also known as DDT.
18689	naphthalene disulfonate 1,2-dioxygenase activity	F	Catalysis of the reaction: (1/2)-unsubstituted naphthalenoid-(2/1)-sulfonate + 2 H+ + 2 e- + O2 = 1,2-dihydroxynaphthalene derivative + HSO3(-). Substrates include naphthalene-1,6-disulfonate (forms 1,2-dihydroxynaphthalene-6-sulfonate), naphthalene-1-sulfonate (forms 1,2-dihydroxynaphthalene), naphthalene-2,6-disulfonate (forms 1,2-dihydroxynaphthalene-6-sulfonate) and naphthalene-2-sulfonate (forms 1,2-dihydroxynaphthalene).
18690	4-methoxybenzoate monooxygenase (O-demethylating) activity	F	Catalysis of the reaction: 4-methoxybenzoate + AH(2) + O(2) = 4-hydroxybenzoate + A + formaldehyde + H(2)O.
18693	ethylbenzene hydroxylase activity	F	Catalysis of the reaction: A + ethylbenzene + H(2)O = (S)-1-phenylethanol + AH(2).
18694	p-cymene methyl hydroxylase activity	F	Catalysis of the reaction: p-cymene + NADH + O2 = NAD+ + OH- + p-cumic alcohol.
18695	4-cresol dehydrogenase (hydroxylating) activity	F	Catalysis of the reaction: 4-cresol + acceptor + H2O = 4-hydroxybenzaldehyde + reduced acceptor.
18697	carbonyl sulfide nitrogenase activity	F	Catalysis of the reaction: carbonyl sulfide + 2 H+ + 2 e- = hydrogen sulfide + carbon monoxide.
18698	vinyl chloride reductive dehalogenase activity	F	Catalysis of the reaction: vinyl chloride + 2 H+ + 2 e- = HCl + ethene.
18699	1,1,1-trichloroethane reductive dehalogenase activity	F	Catalysis of the reaction: 1,1,1-trichloroethane + 2 H+ + 2 e- = 1,1-dichloroethane + HCl.
18700	2-chloro-N-isopropylacetanilide reductive dehalogenase activity	F	Catalysis of the reaction: 2-chloro-N-isopropylacetanilide + H+ + 2 e- = Cl- + N-isopropylacetanilide.
18701	2,5-dichlorohydroquinone reductive dehalogenase activity	F	Catalysis of the reaction: organohalide + 2 H+ + 2 e- = R-H + HCl. Reactants include chlorohydroquinone (forms hydroquinone) and 2,5-dichlorohydroquinone (forms chlorohydroquinone).
18702	1,1-dichloro-2,2-bis(4-chlorophenyl)ethene dehalogenase activity	F	Catalysis of the reaction: 1,1-dichloro-2,2-bis(4-chlorophenyl)ethene + H+ + 2 e- = Cl- + 1-chloro-2,2-bis(4-chlorophenyl)ethene. 1,1-dichloro-2,2-bis(4-chlorophenyl)ethene is also known as DDE; 1-chloro-2,2-bis(4-chlorophenyl)ethene is also known as DDMU.
18703	2,4-dichlorophenoxyacetate dehalogenase activity	F	Catalysis of the reaction: 2,4-dichlorophenoxyacetic acid + H+ + 2 e- = Cl- + 4-chlorophenoxyacetate.
18705	1,2-dichloroethene reductive dehalogenase activity	F	Catalysis of the reaction: 1,2-dichloroethene + 2 H+ + 2 e- = HCl + vinyl chloride.
18706	pyrogallol hydroxytransferase activity	F	Catalysis of the reaction: 1,2,3,5-tetrahydroxybenzene + 1,2,3-trihydroxybenzene = 1,3,5-trihydroxybenzene + 1,2,3,5-tetrahydroxybenzene.
18707	1-phenanthrol methyltransferase activity	F	Catalysis of the reaction: 1-phenanthrol + X-CH3 = X + 1-methoxyphenanthrene.
18708	thiol S-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + a thiol = S-adenosyl-L-homocysteine + a thioether.
18710	acetone carboxylase activity	F	Catalysis of the reaction: acetone + ATP + CO(2) + 2 H(2)O = acetoacetate + AMP + 4 H(+) + 2 phosphate.
18711	benzoyl acetate-CoA thiolase activity	F	Catalysis of the reaction: benzoyl acetyl-CoA + CoA = acetyl-CoA + benzoyl-CoA.
18712	3-hydroxybutyryl-CoA thiolase activity	F	Catalysis of the reaction: 3-hydroxy-5-oxohexanoyl-CoA + CoASH = 3-hydroxybutyryl-CoA + acetyl-CoA.
18713	3-ketopimelyl-CoA thiolase activity	F	Catalysis of the reaction: 3-ketopimeloyl-CoA + CoA = glutaryl-CoA + acetyl-CoA.
18715	9-phenanthrol UDP-glucuronosyltransferase activity	F	Catalysis of the reaction: 9-phenanthrol + UDP-glucuronate = 9-phenanthryl-beta-D-glucuronide + UDP.
18716	1-phenanthrol glycosyltransferase activity	F	Catalysis of the reaction: 1-phenanthrol + glucose = 1-phenanthryl-beta-D-glucopyranoside + H2O.
18717	9-phenanthrol glycosyltransferase activity	F	Catalysis of the reaction: 9-phenanthrol + glucose = 9-phenanthryl-beta-D-glucopyranoside + H2O.
18718	1,2-dihydroxy-phenanthrene glycosyltransferase activity	F	Catalysis of the reaction: 1,2-dihydroxyphenanthrene + UDP-glucose = 2-hydroxy-1-phenanthryl-beta-D-glucopyranoside + UDP.
18719	6-aminohexanoate transaminase activity	F	Catalysis of the reaction: 6-aminohexanoate + alpha-ketoglutarate = glutamate + 6-oxohexanoate.
18720	phenol kinase activity	F	Catalysis of the reaction: phenol + X-HPO3- = XH + phenylphosphate.
18721	trans-9R,10R-dihydrodiolphenanthrene sulfotransferase activity	F	Catalysis of the reaction: trans-9R,10R-dihydrodiolphenanthrene + 2 X-SO3(-) = 2 HX + phenanthrene-9,10-dihydrodiolsulfate conjugate.
18722	1-phenanthrol sulfotransferase activity	F	Catalysis of the reaction: 1-phenanthrol + X-SO3(-) = HX + 1-phenanthrylsulfate.
18723	3-phenanthrol sulfotransferase activity	F	Catalysis of the reaction: 3-phenanthrol + X-SO3(-) = HX + 3-phenanthrylsulfate.
18724	4-phenanthrol sulfotransferase activity	F	Catalysis of the reaction: 4-phenanthrol + X-SO3(-) = HX + 4-phenanthrylsulfate.
18725	trans-3,4-dihydrodiolphenanthrene sulfotransferase activity	F	Catalysis of the reaction: trans-3,4-dihydrodiolphenanthrene + 2 X-SO3(-) = 2 HX + phenanthrene-3,4-dihydrodiolsulfate conjugate.
18726	9-phenanthrol sulfotransferase activity	F	Catalysis of the reaction: 9-phenanthrol + X-SO3(-) = HX + 9-phenanthrylsulfate.
18727	2-phenanthrol sulfotransferase activity	F	Catalysis of the reaction: 2-phenanthrol + X-SO3(-) = HX + 2-phenanthrylsulfate.
18729	propionate CoA-transferase activity	F	Catalysis of the reaction: acetyl-CoA + propanoate = acetate + propanoyl-CoA.
18730	glutaconate CoA-transferase activity	F	Catalysis of the reaction: acetyl-CoA + (E)-glutaconate = acetate + glutaconyl-1-CoA.
18731	1-oxa-2-oxocycloheptane lactonase activity	F	Catalysis of the reaction: 1-oxa-2-oxocycloheptane + H2O = 6-hydroxyhexanoate.
18732	sulfolactone hydrolase activity	F	Catalysis of the reaction: 4-sulfolactone + OH- = HSO3(-) + maleylacetate.
18733	3,4-dihydrocoumarin hydrolase activity	F	Catalysis of the reaction: 3,4-dihydrocoumarin + H2O = 3-(2-hydroxyphenyl) propionate.
18734	butyrolactone hydrolase activity	F	Catalysis of the reaction: butyrolactone + H2O = 4-hydroxybutanoate.
18736	6-oxo-2-hydroxycyclohexane-1-carboxyl-CoA hydrolase activity	F	Catalysis of the reaction: 6-oxo-2-hydroxycyclohexane-1-carboxyl-CoA + H2O = 3-hydroxypimeloyl-CoA.
18737	2-ketocyclohexane-1-carboxyl-CoA hydrolase activity	F	Catalysis of the reaction: 2-ketocyclohexane-1-carboxyl-CoA + H2O = pimeloyl-CoA.
18738	S-formylglutathione hydrolase activity	F	Catalysis of the reaction: S-formylglutathione + H(2)O = formate + glutathione + H(+).
18739	4-hydroxybenzoyl-CoA thioesterase activity	F	Catalysis of the reaction: 4-hydroxybenzoyl-CoA + H(2)O = 4-hydroxybenzoate + CoA + H(+).
18740	2'-hydroxybiphenyl-2-sulfinate desulfinase activity	F	Catalysis of the reaction: 2'-hydroxybiphenyl-2-sulfinate + H(2)O = biphenyl-2-ol + sulfite.
18741	alkyl sulfatase activity	F	Catalysis of the reaction: dodecyl sulfate + H2O = sulfate + H+ + 1-dodecanol.
18742	epoxide hydrolase B activity	F	Catalysis of the hydrolysis of the ether in chloro- or hydroxyepoxypropane to produce chloropropane diol or glycerol. Acts on R enantiomers.
18743	phenanthrene-9,10-epoxide hydrolase (9R,10R-forming) activity	F	Catalysis of the reaction: phenanthrene-9,10-oxide + H2O = trans-9R,10R-dihydrodiolphenanthrene.
18744	limonene-1,2-epoxide hydrolase activity	F	Catalysis of the reaction: limonene-1,2-epoxide + H2O = limonene-1,2-diol. Other substrates include alicyclic and 1-methyl-substituted epoxides, such as 1-methylcyclohexene oxide, indene oxide and cyclohexene oxide.
18745	epoxide hydrolase A activity	F	Catalysis of the hydrolysis of the ether in chloro-, bromo- or hydroxyepoxypropane to produce a chloro- or bromopropane diol or glycerol.
18746	phenanthrene-3,4-epoxide hydrolase activity	F	Catalysis of the reaction: phenanthrene-3,4-oxide + H2O = trans-3,4-dihydrodiolphenanthrene.
18747	phenanthrene-1,2-epoxide hydrolase activity	F	Catalysis of the reaction: phenanthrene-1,2-oxide + H2O = trans-1,2-dihydrodiolphenanthrene.
18748	iprodione amidohydrolase activity	F	Catalysis of the reaction: iprodione + OH- = 3,5-dichlorophenylcarboximide + N-isopropylcarbamate.
18749	(3,5-dichlorophenylurea)acetate amidohydrolase activity	F	Catalysis of the reaction: (3,5-dichlorophenylurea)acetate + OH- = 3,5-dichloroaniline + N-carboxyglycine.
18750	biuret amidohydrolase activity	F	Catalysis of the reaction: biuret + H2O = urea + CO2 + NH3.
18751	3,5-dichlorophenylcarboximide hydrolase activity	F	Catalysis of the reaction: 3,5-dichlorophenylcarboximide + OH- = (3,5-dichlorophenylurea)acetate.
18752	epsilon-caprolactam lactamase activity	F	Catalysis of the reaction: epsilon-caprolactam + H2O = H+ + 6-aminohexanoate.
18753	cyanuric acid amidohydrolase activity	F	Catalysis of the reaction: cyanuric acid + H2O = biuret + CO2.
18754	ammelide aminohydrolase activity	F	Catalysis of the reaction: ammelide + H2O = cyanuric acid + NH3.
18755	2-chloro-4-hydroxy-6-amino-1,3,5-triazine aminohydrolase activity	F	Catalysis of the reaction: 2-chloro-4-hydroxy-6-amino-1,3,5-triazine + OH- = 2,4-dihydroxy-6-amino-1,3,5-triazine + Cl-.
18756	ammeline aminohydrolase activity	F	Catalysis of the reaction: ammeline + H2O = ammelide + NH3.
18757	deisopropylhydroxyatrazine aminohydrolase activity	F	Catalysis of the reaction: deisopropylhydroxyatrazine + H2O = NH3 + 2,4-dihydroxy-6-(N'-ethyl)amino-1,3,5-triazine.
18758	2,4-dihydroxy-6-(N'-ethyl)amino-1,3,5-triazine aminohydrolase activity	F	Catalysis of the reaction: 2,4-dihydroxy-6-(N'-ethyl)amino-1,3,5-triazine + H2O = CH3CH2NH2 + cyanuric acid.
18759	methenyltetrahydromethanopterin cyclohydrolase activity	F	Catalysis of the reaction: 5,10-methenyl-5,6,7,8-tetrahydromethanopterin + H(2)O = N(5)-formyl-5,6,7,8-tetrahydromethanopterin + H(+).
18760	thiocyanate hydrolase activity	F	Catalysis of the reaction: H(2)O + 2 H(+) + thiocyanate = carbonyl sulfide + NH(4)(+).
18761	bromoxynil nitrilase activity	F	Catalysis of the reaction: 3,5-dibromo-4-hydroxybenzonitrile + 2 H(2)O = 3,5-dibromo-4-hydroxybenzoate + NH(4)(+). Involved in the bacterial degradation of the herbicide bromoxynil.
18762	aliphatic nitrilase activity	F	Catalysis of the reaction: R-CN + H2O = R-COOH + NH3.
18763	hydroxydechloroatrazine ethylaminohydrolase activity	F	Catalysis of the reaction: 4-(ethylamino)-2-hydroxy-6-(isopropylamino)-1,3,5-triazine + H2O = N-isopropylammelide + ethylamine.
18764	N-isopropylammelide isopropylaminohydrolase activity	F	Catalysis of the reaction: N-isopropylammelide + H2O = cyanuric acid + isopropylamine.
18765	2-hydroxy-6-oxohepta-2,4-dienoate hydrolase activity	F	Catalysis of the reaction: cis,cis-2-hydroxy-6-oxohept-2,4-dienoate + OH- = cis-2-hydroxypenta-2,4-dienoate + acetate.
18766	dihydrophloroglucinol hydrolase activity	F	Catalysis of the reaction: dihydrophloroglucinol + OH- = 3-hydroxy-5-oxohexanoate.
18767	2-hydroxy-6-oxo-7-methylocta-2,4-dienoate hydrolase activity	F	Catalysis of the reaction: 2-hydroxy-6-oxo-7-methylocta-2,4-dienoate + H2O = cis-2-hydroxypenta-2,4-dienoate + isobutyrate.
18768	2-hydroxy-6-oxo-6-(2'-aminophenyl)hexa-2,4-dienoate hydrolase activity	F	Catalysis of the reaction: 2-hydroxy-6-oxo-(2'-aminophenyl)-hexa-2,4-dienoate + H2O = 2-aminobenzoate + cis-2-hydroxypenta-2,4-dienoate.
18769	2-hydroxy-6-oxoocta-2,4-dienoate hydrolase activity	F	Catalysis of the reaction: 2-hydroxy-6-oxoocta-2,4-dienoate + H2O = H+ + propanoate + cis-2-hydroxypenta-2,4-dienoate.
18770	6-oxo-2-hydroxy-7-(4'-chlorophenyl)-3,8,8-trichloroocta-2E,4E,7-trienoate hydrolase activity	F	Catalysis of the reaction: 6-oxo-2-hydroxy-7-(4'-chlorophenyl)-3,8,8-trichloroocta-2Z,4Z,7-trienoate + H2O = 2-(4'-chlorophenyl)-3,3-dichloropropenoate + cis-2-Hydroxy-3-chloropenta-2,4-dienone + H+.
18771	2-hydroxy-6-oxonona-2,4-dienedioate hydrolase activity	F	Catalysis of the reaction: (2E,4Z)-2-hydroxy-6-oxonona-2,4-dienedioate + H2O = (2E)-2-hydroxypenta-2,4-dienoate + H+ + succinate.
18772	trioxoheptanoate hydrolase activity	F	Catalysis of the reaction: 2,4,6-trioxoheptanoate + H2O = acetylpyruvate + acetate.
18773	acetylpyruvate hydrolase activity	F	Catalysis of the reaction: acetylpyruvate + H(2)O = acetate + H(+) + pyruvate.
18774	2,6-dioxo-6-phenylhexa-3-enoate hydrolase activity	F	Catalysis of the reaction: 2,6-dioxo-6-phenylhexa-3-enoate + H2O = benzoate + 2-oxopent-4-enoate.
18775	2-hydroxymuconate-semialdehyde hydrolase activity	F	Catalysis of the reaction: 2-hydroxymuconate semialdehyde + H2O = formate + 2-oxopent-4-enoate.
18776	trans-chloroacrylic acid dehalogenase activity	F	Catalysis of the reaction: trans-3-chloroacrylic acid + H2O = H+ + malonate semialdehyde.
18777	1,3,4,6-tetrachloro-1,4-cyclohexadiene halidohydrolase activity	F	Catalysis of the reaction: alkyl halide + H2O = alcohol + HCl. Substrates are 1,3(R),4,6(R)-tetrachloro-1,4-cyclohexadiene (forms 2,4,5-trichloro-2,5-cyclohexadiene-1-ol) and 2,4,5-trichloro-2,5-cyclohexadiene-1-ol (forms 2,5-dichloro-2,5-cyclohexadiene-1,4-diol).
18778	DL-2 haloacid dehalogenase activity	F	Catalysis of the reaction: trichloroacetate + 2 H2O = 3 H+ + 3 Cl- + oxalate.
18780	dichloroacetate halidohydrolase activity	F	Catalysis of the reaction: dichloroacetate + H2O = 2 HCl + glyoxylate.
18781	S-triazine hydrolase activity	F	Catalysis of the reaction: 1-halo or 1-pseudohalo-S-triazine = 1-hydroxy-S-triazine.
18782	cis-chloroacrylic acid dehalogenase activity	F	Catalysis of the reaction: cis-3-chloroacrylic acid + H2O = H+ + HCl + malonate semialdehyde.
18783	deisopropyldeethylatrazine hydrolase activity	F	Catalysis of the reaction: deisopropyldeethylatrazine + H2O = 2-chloro-4-hydroxy-6-amino-1,3,5-triazine + NH3.
18784	(S)-2-haloacid dehalogenase activity	F	Catalysis of the reaction: (S)-2-haloacid + H2O = (R)-2-hydroxyacid + halide.
18785	haloacetate dehalogenase activity	F	Catalysis of the reaction: haloacetate + H2O = glycolate + halide.
18786	haloalkane dehalogenase activity	F	Catalysis of the reaction: 1-haloalkane + H2O = a primary alcohol + halide.
18787	4-chlorobenzoyl-CoA dehalogenase activity	F	Catalysis of the reaction: 4-chlorobenzoyl-CoA + H2O = 4-hydroxybenzoyl CoA + chloride.
18788	atrazine chlorohydrolase activity	F	Catalysis of the reaction: atrazine + H(2)O = 4-(ethylamino)-2-hydroxy-6-(isopropylamino)-1,3,5-triazine + chloride + H(+).
18789	cyclamate sulfohydrolase activity	F	Catalysis of the reaction: cyclohexylsulfamate + H(2)O = cyclohexylamine + sulfate.
18791	2-hydroxy-3-carboxy-6-oxo-7-methylocta-2,4-dienoate decarboxylase activity	F	Catalysis of the reaction: 2-hydroxy-3-carboxy-6-oxo-7-methylocta-2,4-dienoate = CO2 + 2-hydroxy-6-oxo-7-methylocta-2,4-dienoate.
18792	bis(4-chlorophenyl)acetate decarboxylase activity	F	Catalysis of the reaction: bis(4-chlorophenyl)acetate + H+ = CO2 + bis(4-chlorophenyl)methane. Bis(4-chlorophenyl)acetate is also known as DDA; bis(4-chlorophenyl)methane is also known as DDM.
18793	3,5-dibromo-4-hydroxybenzoate decarboxylase activity	F	Catalysis of the reaction: 3,5-dibromo-4-hydroxybenzoate + H+ = CO2 + 2,6-dibromophenol.
18794	2-hydroxyisobutyrate decarboxylase activity	F	Catalysis of the reaction: 2-hydroxyisobutyrate + H+ = CO2 + 2-propanol.
18795	2-hydroxy-2-methyl-1,3-dicarbonate decarboxylase activity	F	Catalysis of the reaction: 2-hydroxy-2-methyl-1,3-dicarbonate + H+ = CO2 + L-lactate.
18796	4,5-dihydroxyphthalate decarboxylase activity	F	Catalysis of the reaction: 4,5-dihydroxyphthalate = 3,4-dihydroxybenzoate + CO2.
18798	gallate decarboxylase activity	F	Catalysis of the reaction: gallate + H(+) = CO(2) + pyrogallol.
18799	4-hydroxybenzoate decarboxylase activity	F	Catalysis of the reaction: 4-hydroxybenzoate + H(+) = CO(2) + phenol.
18800	5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase activity	F	Catalysis of the reaction: 5-oxopent-3-ene-1,2,5-tricarboxylate = 2-oxohept-3-enedioate + CO2.
18801	glutaconyl-CoA decarboxylase activity	F	Catalysis of the reaction: trans-glutaconyl-CoA + H(+) = but-2-enoyl-CoA + CO(2).
18802	2,4-dihydroxyhept-2-ene-1,7-dioate aldolase activity	F	Catalysis of the reaction: 2,4-dihydroxy-hept-trans-2-ene-1,7-dioate = pyruvate + succinic semialdehyde.
18803	4-(2-carboxyphenyl)-2-oxobut-3-enoate aldolase activity	F	Catalysis of the reaction: (3E)-4-(2-carboxyphenyl)-2-oxobut-3-enoate = 2-carboxybenzaldehyde + pyruvate.
18805	benzylsuccinate synthase activity	F	Catalysis of the reaction: fumarate + toluene = 2-benzylsuccinate.
18807	6-hydroxycyclohex-1-ene-1-carboxyl-CoA hydratase activity	F	Catalysis of the reaction: 6-hydroxycyclohex-1-ene-1-carboxyl-CoA + H2O = 2,6-dihydroxycyclohexane-1-carboxyl-CoA.
18808	trans-4-(1'-hydroxynaphth-2'-yl)-2-oxobut-3-enoate hydratase-aldolase activity	F	Catalysis of the reaction: trans-4-(1'-hydroxynaphth-2'-yl)-2-oxobut-3-enoate + H2O = pyruvate + 1-hydroxy-2-naphthaldehyde.
18809	E-phenylitaconyl-CoA hydratase activity	F	Catalysis of the reaction: E-phenylitaconyl-CoA + H2O = (hydroxymethylphenyl)succinyl-CoA.
18810	trans-4-[2-(3-hydroxy)-thionaphthenyl]-2-oxo-3-butenoate hydratase activity	F	Catalysis of the reaction: trans-4-(2-(3-hydroxy)-thionaphthenyl)-2-oxo-3-butenoate + H2O = pyruvate + 3-hydroxy-2-formylbenzothiophene.
18811	cyclohex-1-ene-1-carboxyl-CoA hydratase activity	F	Catalysis of the reaction: cyclohex-1-ene-1-carboxyl-CoA + H2O = 2-hydroxycyclohexane-1-carboxyl-CoA.
18812	3-hydroxyacyl-CoA dehydratase activity	F	Catalysis of the reaction: alkene-CoA + H2O = alcohol-CoA. Substrates are crotonoyl-CoA (producing 3-hydroxyacyl-CoA) and 2,3-didehydro-pimeloyl-CoA (producing 3-hydroxypimeloyl-CoA).
18813	trans-o-hydroxybenzylidenepyruvate hydratase-aldolase activity	F	Catalysis of the reaction: 2-oxo-3-enoate-4-benzenoid + H2O = pyruvate + benzaldehyde derivative. Substrates are (3E)-4-(5-amino-2-hydroxy-phenyl)-2-oxo-but-3-ene-1-oic-acid (forms 5-aminosalicylaldehyde) and trans-o-hydroxybenzylidenepyruvate (forms salicylaldehyde).
18814	phenylacetaldoxime dehydratase activity	F	Catalysis of the reaction: (trans)-phenylacetaldoxime = H(2)O + phenylacetonitrile.
18815	3-methyl-5-hydroxy-6-(3-carboxy-3-oxopropenyl)-1H-2-pyridon hydratase-aldolase activity	F	Catalysis of the reaction: 3-methyl-5-hydroxy-6-(3-carboxy-3-oxopropenyl)-1H-2-pyridon + H2O = 2-oxobut-3-enanoate + 2,5,6-trihydroxy-3-methylpyridine.
18816	2-hydroxyisobutyrate dehydratase activity	F	Catalysis of the reaction: 2-hydroxyisobutyrate = H2O + methacrylate.
18817	2-oxo-hept-3-ene-1,7-dioate hydratase activity	F	Catalysis of the reaction: cis-2-oxohept-3-ene-1,7-dioate + H2O = 2,4-dihydroxy-hept-trans-2-ene-1,7-dioate.
18818	acetylene hydratase activity	F	Catalysis of the reaction: acetaldehyde = acetylene + H(2)O.
18819	lactoyl-CoA dehydratase activity	F	Catalysis of the reaction: lactoyl-CoA = acryloyl-CoA + H2O.
18820	cyanamide hydratase activity	F	Catalysis of the reaction: urea = cyanamide + H(2)O.
18822	nitrile hydratase activity	F	Catalysis of the reaction: an aliphatic amide = a nitrile + H2O.
18823	cyclohexa-1,5-dienecarbonyl-CoA hydratase activity	F	Catalysis of the reaction: cyclohexa-1,5-diene-1-carbonyl-CoA + H(2)O = 6-hydroxycyclohex-1-enecarbonyl-CoA.
18824	(hydroxyamino)benzene mutase activity	F	Catalysis of the reaction: (hydroxyamino)benzene = 2-aminophenol.
18825	triethanolamine lyase activity	F	Catalysis of the reaction: triethanolamine = diethanolamine + acetaldehyde.
18826	methionine gamma-lyase activity	F	Catalysis of the reaction: L-methionine = methanethiol + NH3 + 2-oxobutanoate.
18827	1-chloro-2,2-bis(4-chlorophenyl)ethane dehydrochlorinase activity	F	Catalysis of the reaction: 1-chloro-2,2-bis(4-chlorophenyl)ethane = HCl + unsym-bis(4-chlorophenyl)ethene. 1-chloro-2,2-bis(4-chlorophenyl)ethane is also known as DDMS; unsym-bis(4-chlorophenyl)ethene is also known as DDNU.
18828	halohydrin hydrogen-halide-lyase A activity	F	Catalysis of the elimination of HCl from a chloro- or bromopropanol, yielding an epoxypropane.
18829	1,1-dichloro-2,2-bis(4-chlorophenyl)ethane dehydrochlorinase activity	F	Catalysis of the reaction: 1,1-dichloro-2,2-bis(4-chlorophenyl)ethane = HCl + 1-chloro-2,2-bis(4-chlorophenyl)ethene. 1,1-dichloro-2,2-bis(4-chlorophenyl)ethane is also known as DDD; 1-chloro-2,2-bis(4-chlorophenyl)ethene is also known as DDMU.
18830	gamma-hexachlorocyclohexane dehydrochlorinase activity	F	Catalysis of the reaction: gamma-hexachlorocyclohexane + HCl = 1,3(R),4(S),5(S),6(R)-pentachlorocyclohexene.
18831	5-chloro-1,2,4-trihydroxybenzene dechlorinase activity	F	Catalysis of the reaction: 5-chloro-1,2,4-trihydroxybenzene = Cl- + H+ + 2-hydroxy-1,4-benzoquinone.
18832	halohydrin hydrogen-halide-lyase B activity	F	Catalysis of the elimination of HCl from a chloropropanol, yielding an epoxypropane.
18833	DDT-dehydrochlorinase activity	F	Catalysis of the reaction: 1,1,1-trichloro-2,2-bis(4-chlorophenyl)ethane = 1,1-dichloro-2,2-bis(4-chlorophenyl)ethylene + chloride + H(+).
18834	dichloromethane dehalogenase activity	F	Catalysis of the reaction: dichloromethane + H(2)O = 2 chloride + formaldehyde + 2 H(+).
18835	carbon phosphorus lyase activity	F	Catalysis of the reaction: alkylphosphonic acid = R-CH3 + phosphate. Substrates include aminomethylphosphonic acid (AMPA) (forms methylamine), dimethylphosphinic acid (forms methylphosphonic acid), glyphosate (forms sarcosine) and methylphosphonic acid (forms phosphate).
18836	alkylmercury lyase activity	F	Catalysis of the reaction: R-Hg+ + H+ = R-H + Hg2+.
18837	2-hydroxy-2H-benzo[h]chromene-2-carboxylate isomerase activity	F	Catalysis of the reaction: 2-hydroxy-2 H-benzo[h]chromene-2-carboxylate = cis -4-(1'-hydroxynaphth-2'-yl)-2-oxobut-3-enoate.
18838	mandelate racemase activity	F	Catalysis of the reaction: (S)-mandelate = (R)-mandelate.
18839	cis-4-[2-(3-hydroxy)-thionaphthenyl]-2-oxo-3-butenoate isomerase activity	F	Catalysis of the reaction: cis-4-(2-(3-hydroxy)-thionaphthenyl)-2-oxo-3-butenoate = trans-4-(2-(3-hydroxy)-thionaphthenyl)-2-oxo-3-butenoate.
18842	3-carboxymuconate cycloisomerase type II activity	F	Catalysis of the reaction: 3-sulfomuconate = 4-sulfolactone.
18844	2-hydroxytetrahydrofuran isomerase activity	F	Catalysis of the reaction: 2-hydroxytetrahydrofuran = 4-hydroxybutyraldehyde.
18845	2-hydroxychromene-2-carboxylate isomerase activity	F	Catalysis of the reaction: 2-hydroxychromene-2-carboxylate = (3E)-4-(2-hydroxyphenyl)-2-oxobut-3-enoate. (3E)-4-(2-hydroxyphenyl)-2-oxobut-3-enoate is also known as trans-o-hydroxybenzylidenepyruvate.
18846	styrene-oxide isomerase activity	F	Catalysis of the reaction: styrene oxide = phenylacetaldehyde.
18847	alpha-pinene lyase activity	F	Catalysis of the reaction: alpha-pinene = limonene.
18848	pinocarveol isomerase activity	F	Catalysis of the reaction: pinocarveol = carveol.
18849	muconate cycloisomerase activity	F	Catalysis of the reaction: 2,5-dihydro-5-oxofuran-2-acetate = cis,cis-hexadienedioate.
18850	chloromuconate cycloisomerase activity	F	Catalysis of the reaction: 2-chloro-2,5-dihydro-5-oxofuran-2-acetate = 3-chloro-cis,cis-muconate.
18851	alpha-pinene-oxide decyclase activity	F	Catalysis of the reaction: alpha-pinene oxide = (Z)-2-methyl-5-isopropylhexa-2,5-dienal.
18852	dichloromuconate cycloisomerase activity	F	Catalysis of the reaction: 2,4-dichloro-2,5-dihydro-5-oxofuran-2-acetate = 2,4-dichloro-cis,cis-muconate.
18854	3-isopropenyl-6-oxoheptanoyl-CoA synthetase activity	F	Catalysis of the reaction: (3R)-3-isopropenyl-6-oxoheptanoate + CoA-SH + ATP = H2O + ADP/AMP + mono/diphosphate + (3R)-3-isopropenyl-6-oxoheptanoyl-CoA.
18855	2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA synthetase activity	F	Catalysis of the reaction: 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetate + ATP + CoA = AMP + diphosphate + 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA.
18856	benzoyl acetate-CoA ligase activity	F	Catalysis of the reaction: 3-oxo-3-phenylpropionate + CoA + ATP = AMP + diphosphate + benzoyl acetyl-CoA.
18857	2,4-dichlorobenzoate-CoA ligase activity	F	Catalysis of the reaction: 2,4-dichlorobenzoate + ATP + CoASH = AMP + diphosphate + 2,4-dichlorobenzoyl-CoA.
18858	benzoate-CoA ligase activity	F	Catalysis of the reaction: ATP + benzoate + CoA = AMP + benzoyl-CoA + diphosphate + H(+).
18859	4-hydroxybenzoate-CoA ligase activity	F	Catalysis of the reaction: ATP + 4-hydroxybenzoate + CoA = AMP + diphosphate + 4-hydroxybenzoyl-CoA.
18860	anthranilate-CoA ligase activity	F	Catalysis of the reaction: ATP + anthranilate + CoA = AMP + diphosphate + anthranilyl-CoA.
18861	4-chlorobenzoate-CoA ligase activity	F	Catalysis of the reaction: 4-chlorobenzoate + CoA + ATP = 4-chlorobenzoyl-CoA + AMP + diphosphate. This reaction requires magnesium and is part of the bacterial 2,4-dichlorobenzoate degradation pathway.
18862	phenylphosphate carboxylase activity	F	Catalysis of the reaction: phenylphosphate + CO2 + H2O = H+ + phosphate + 4-hydroxybenzoate.
18863	phenanthrene-9,10-epoxide hydrolase (9S,10S-forming) activity	F	Catalysis of the reaction: phenanthrene-9,10-oxide + H2O = trans-9(S),10(S)-dihydrodiolphenanthrene.
18864	acetylene metabolic process	P	The chemical reactions and pathways involving acetylene, formula CH2CH2, the simplest of the alkynes.
18865	acrylonitrile metabolic process	P	The chemical reactions and pathways involving acrylonitrile, a colorless, volatile liquid with a pungent odor. Acrylonitrile is used in the production of acrylic fibers, plastics, and synthetic rubbers.
18866	adamantanone metabolic process	P	The chemical reactions and pathways involving adamantanone, tricyclo(3.3.1.13,7)decanone, a white crystalline solid used as an intermediate for microelectronics in the production of photoresists.
18867	alpha-pinene metabolic process	P	The chemical reactions and pathways involving alpha-pinene, a monoterpene that may be a significant factor affecting bacterial activities in nature. It is a major component in tea-tree oils, and gives off a piney smelling odor.
18868	2-aminobenzenesulfonate metabolic process	P	The chemical reactions and pathways involving 2-aminobenzenesulfonate, aniline-o-sulfonic acid, an aromatic sulfonate used in organic synthesis and in the manufacture of various dyes and medicines.
18870	anaerobic 2-aminobenzoate metabolic process	P	The chemical reactions and pathways resulting in the breakdown of 2-aminobenzoate, a derivative of benzoic acid with an NH2 group attached to C2, that occurs in the absence of oxygen.
18871	1-aminocyclopropane-1-carboxylate metabolic process	P	The chemical reactions and pathways involving 1-aminocyclopropane-1-carboxylate, the anion of 1-aminocyclopropane-1-carboxylic acid, a natural product found in plant tissues. It is a key intermediate in the biosynthesis of ethylene (ethene), a fruit-ripening hormone in plants.
18872	arsonoacetate metabolic process	P	The chemical reactions and pathways involving arsonoacetate, a synthetic, organic compound containing a single arsenic atom. Arsonoacetate and other arsenic containing compounds are used in agricultural applications as animal feed additives, cotton defoliants and post-emergence grass herbicides.
18873	atrazine metabolic process	P	The chemical reactions and pathways involving atrazine, a triazine ring-containing compound, widely used as a herbicide.
18874	benzoate metabolic process	P	The chemical reactions and pathways involving benzoate, the anion of benzoic acid (benzenecarboxylic acid), a fungistatic compound widely used as a food preservative; it is conjugated to glycine in the liver and excreted as hippuric acid.
18875	anaerobic benzoate metabolic process	P	The chemical reactions and pathways involving benzoate, the anion of benzoic acid (benzenecarboxylic acid) that occur in the absence of oxygen.
18876	benzonitrile metabolic process	P	The chemical reactions and pathways involving benzonitrile. Benzonitrile is used as a solvent and chemical intermediate in the pharmaceutical, dyestuffs and rubber industries. It is highly toxic and harmful in contact with skin.
18877	beta-1,2,3,4,5,6-hexachlorocyclohexane metabolic process	P	The chemical reactions and pathways involving beta-1,2,3,4,5,6-hexachlorocyclohexane, a halogenated organic insecticide that has been used worldwide for agriculture and public health.
18878	aerobic beta-1,2,3,4,5,6-hexachlorocyclohexane metabolic process	P	The chemical reactions and pathways involving beta-1,2,3,4,5,6-hexachlorocyclohexane that occur in presence of oxygen.
18879	biphenyl metabolic process	P	The chemical reactions and pathways involving biphenyl, a toxic aromatic hydrocarbon used as a heat transfer agent, as a fungistat in packaging citrus fruits and in plant disease control. Biphenyl can be chlorinated with 1-10 chlorine molecules to form polychlorinated biphenyls (PCBs).
18880	4-chlorobiphenyl metabolic process	P	The chemical reactions and pathways involving 4-chlorobiphenyl, a member of the polychlorinated biphenyl (PCB) group of compounds, a very stable group of synthetic organic compounds composed of a biphenyl nucleus with 1-10 chlorine substituents. 4-chlorobiphenyl has been used as a model substrate to investigate PCB degradation.
18881	bromoxynil metabolic process	P	The chemical reactions and pathways involving bromoxynil, C7H3Br2NO, a dibrominated phenol derivative with a cyano (-CN) group attached. Bromoxynil is used as a herbicide for post-emergent control of annual broadleaf weeds and works by inhibiting photosynthesis in the target plants.
18882	(+)-camphor metabolic process	P	The chemical reactions and pathways involving (+)-camphor, a bicyclic monoterpene ketone which is one of the major components in the leaves of common sage. Camphor exists in two enantiomers, but the (+)-isomer is more widely distributed.
18883	caprolactam metabolic process	P	The chemical reactions and pathways involving caprolactam, hexahydro-2h-azepin-2-one, a cyclic amide of caproic acid used in manufacture of synthetic fibers of the polyamide type. It can cause local irritation.
18884	carbazole metabolic process	P	The chemical reactions and pathways involving carbazole, a heterocyclic aromatic compound containing a dibenzopyrrole system that is produced during coal gasification and is present in cigarette smoke. Coal tar produced at high temperature contains an average of 1.5% carbazole. It is used widely in synthesis of dyes, pharmaceuticals, and plastics and is a suspected carcinogen.
18885	carbon tetrachloride metabolic process	P	The chemical reactions and pathways involving carbon tetrachloride, a toxic, carcinogenic compound which is used as a general solvent in industrial degreasing operations. It is also used as grain fumigant and a chemical intermediate in the production of refrigerants.
18886	anaerobic carbon tetrachloride metabolic process	P	The chemical reactions and pathways involving carbon tetrachloride, a toxic, carcinogenic compound which is used as a general solvent in industrial degreasing operations, that occur in the absence of oxygen.
18887	4-carboxy-4'-sulfoazobenzene metabolic process	P	The chemical reactions and pathways involving 4-carboxy-4'-sulfoazobenzene, a sulfonated azo compound synthesized by nitro-amine condensation from sulfanilic acid and 4-nitrobenzoic acid.
18888	3-chloroacrylic acid metabolic process	P	The chemical reactions and pathways involving 3-chloroacrylic acid, ClHC=CHCOOH, a chlorinated derivative of acrylic acid.
18889	2-chloro-N-isopropylacetanilide metabolic process	P	The chemical reactions and pathways involving 2-chloro-N-isopropylacetanilide, an acylanide herbicide widely used to protect corn, onion, cabbage, rose bushes, and ornamental plants.
18890	cyanamide metabolic process	P	The chemical reactions and pathways involving cyanamide, NCNH2, a cyanide compound which has been used as a fertilizer, defoliant and in many manufacturing processes. It often occurs as the calcium salt, sometimes also referred to as cyanamide. The citrated calcium salt is used in the treatment of alcoholism.
18891	cyclohexanol metabolic process	P	The chemical reactions and pathways involving cyclohexanol, the monohydroxy derivative of cyclohexane. It is used as a solvent and blending agent.
18892	cyclohexylsulfamate metabolic process	P	The chemical reactions and pathways involving cyclohexylsulfamate, also known as cyclamic acid. Sodium cyclohexylsulfamate (CHS-Na) was a widely used sweetening agent but was banned because of the suspicion of carcinogenicity and metabolic conversion to cyclohexylamine (CHA), a toxic substance. It is now used as a fungicide.
18893	dibenzofuran metabolic process	P	The chemical reactions and pathways involving dibenzofuran, a substance composed of two benzene rings linked by one ether bond and one carbon-carbon bond. Dibenzofuran is a white crystalline solid created from the production of coal tar and used as an insecticide and an intermediate in the production of other chemicals.
18894	dibenzo-p-dioxin metabolic process	P	The chemical reactions and pathways involving dibenzo-p-dioxin, a substance composed of two benzene rings linked by two ether bonds. Dibenzo-p-dioxins are generated as by-products in the manufacturing of herbicides, insecticides, fungicides, paper pulp bleaching, and in incineration, and can accumulate in milk and throughout the food chain, creating significant health concern.
18895	dibenzothiophene metabolic process	P	The chemical reactions and pathways involving dibenzothiophene, a substance composed of two benzene rings linked by one sulfide bond and one carbon-carbon bond. Dibenzothiophene derivatives can be detected in diesel oil following hydrodesulfurization treatment to remove sulfur compounds that would otherwise generate sulfur oxides during combustion.
18896	dibenzothiophene catabolic process	P	The chemical reactions and pathways resulting in the breakdown of dibenzothiophene, a substance composed of two benzene rings linked by one sulfide bond and one carbon-carbon bond.
18897	dibenzothiophene desulfurization	P	The removal of the sulfur atom from dibenzothiophene, a substance composed of two benzene rings linked by one sulfide bond and one carbon-carbon bond.
18898	2,4-dichlorobenzoate metabolic process	P	The chemical reactions and pathways involving 2,4-dichlorobenzoate, a chlorinated aromatic compound which is a key intermediate in the aerobic degradation of polychlorinated biphenyls (PCBs).
18899	1,2-dichloroethane metabolic process	P	The chemical reactions and pathways involving 1,2-dichloroethane, a major commodity chemical used, for example, in the manufacture of vinyl chloride.
18900	dichloromethane metabolic process	P	The chemical reactions and pathways involving dichloromethane, a dichlorinated derivative of methane. It is a colorless organic liquid with a sweet, chloroform-like odor, often used as a paint remover.
18901	2,4-dichlorophenoxyacetic acid metabolic process	P	The chemical reactions and pathways involving 2,4-dichlorophenoxyacetic acid, a chlorinated phenoxy compound which functions as a systemic herbicide and is used to control many types of broadleaf weeds.
18902	1,3-dichloro-2-propanol metabolic process	P	The chemical reactions and pathways involving 1,3-dichloro-2-propanol (DCP), a halohydrin suspected of being carcinogenic, mutagenic and genotoxic. DCP is used as a general solvent, as an intermediate in organic synthesis and in paints, varnishes, lacquers, water colors, binders and photographic lacquers.
18903	1,3-dichloropropene metabolic process	P	The chemical reactions and pathways involving members of the 1,3-dichloropropene family, which includes cis- and trans-1,3-dichloropropene. The 1,3-dichloropropenes are chlorinated hydrocarbons and the major active ingredients of commercial products for control of plant-parasitic nematodes.
18904	ether metabolic process	P	The chemical reactions and pathways involving organic ethers, any anhydride of the general formula R1-O-R2, formed between two identical or nonidentical organic hydroxy compounds.
18905	dimethyl ether metabolic process	P	The chemical reactions and pathways involving dimethyl ether, CH3-O-CH3, the simplest ether. Dimethyl ether, also known wood ether and methyl ether, is a colorless gas that has been used in refrigeration applications.
18906	methyl tert-butyl ether metabolic process	P	The chemical reactions and pathways involving methyl tert-butyl ether, 2-methoxy-2-methylpropane. Methyl tert-butyl ether is a synthetic chemical which is mixed with gasoline for use in reformulated gasoline. It was first introduced as an additive for unleaded gasoline in the 1980s. It is also used as a laboratory reagent and a pharmaceutical agent.
18907	dimethyl sulfoxide metabolic process	P	The chemical reactions and pathways involving dimethyl sulfoxide, DMSO (C2H6OS), an alkyl sulfoxide that is practically odorless in its purified form. As a highly polar organic liquid, it is a powerful solvent. Its biological activities include the ability to penetrate plant and animal tissues and to preserve living cells during freezing.
18908	organosulfide cycle	P	A cyclic series of interconversions involving dimethyl sulfide, methanethiol and hydrogen sulfide. Dimethylsulfoxide can also be converted to dimethyl sulfide, which enters the cycle.
18909	dodecyl sulfate metabolic process	P	The chemical reactions and pathways involving dodecyl sulfate, commonly found as sodium dodecyl sulfate (SDS), a component of a variety of synthetic surfactants.
18910	benzene metabolic process	P	The chemical reactions and pathways involving benzene, C6H6, a volatile, very inflammable liquid, contained in the naphtha produced by the destructive distillation of coal, from which it is separated by fractional distillation.
18911	1,2,4-trichlorobenzene metabolic process	P	The chemical reactions and pathways involving 1,2,4-trichlorobenzene, a derivative of benzene with chlorine atoms attached to positions 1, 2 and 4 of the ring. It is a colorless liquid used as a solvent in chemical manufacturing, in dyes and intermediates, dielectric fluid, synthetic transformer oils, lubricants, heat-transfer medium and insecticides.
18912	1,4-dichlorobenzene metabolic process	P	The chemical reactions and pathways involving 1,4-dichlorobenzene (p-dichlorobenzene or paramoth), a derivative of benzene with two chlorine atoms attached at opposite positions on the ring. It forms white crystals at room temperature and is used as an insecticidal fumigant, particularly in mothballs.
18913	anaerobic ethylbenzene metabolic process	P	The chemical reactions and pathways involving ethylbenzene (phenylethane), a benzene derivative with an ethyl group attached to the ring, that occur in the absence of oxygen.
18914	chlorobenzene metabolic process	P	The chemical reactions and pathways involving chlorobenzene, a derivative of benzene with a chlorine atoms attached to the ring. It is a colorless liquid that is manufactured for use as a solvent. It quickly evaporates in the air and is degraded by hydroxyl radicals that are produced photochemically. The gas acts as a source of ClOx, which helps in the breakdown of stratospheric ozone.
18915	ethylbenzene metabolic process	P	The chemical reactions and pathways involving ethylbenzene (phenylethane), a benzene derivative with an ethyl group attached to the ring. It is a colorless liquid with a pungent odor used as a solvent and as a component of automotive and aviation fuels.
18916	nitrobenzene metabolic process	P	The chemical reactions and pathways involving nitrobenzene (nitrobenzol), a derivative of benzene with an NO2 group attached to the ring. It is a yellow aromatic liquid used in perfumery and manufactured in large quantities in the preparation of aniline.
18917	fluorene metabolic process	P	The chemical reactions and pathways involving fluorene, a tricyclic polycyclic aromatic hydrocarbon containing a five-membered ring. It is a major component of fossil fuels and their derivatives and is also a by-product of coal-conversion and energy-related industries. It is commonly found in vehicle exhaust emissions, crude oils, motor oils, coal and oil combustion products, waste incineration, and industrial effluents.
18918	gallate metabolic process	P	The chemical reactions and pathways involving gallate, the anion of gallic acid (3,4,5-trihydroxybenzoic acid). The esters and polyesters are widely distributed in angiosperms.
18919	gamma-1,2,3,4,5,6-hexachlorocyclohexane metabolic process	P	The chemical reactions and pathways involving gamma-1,2,3,4,5,6-hexachlorocyclohexane (also known as Lindane), the most common form of hexachlorohexane, a halogenated organic insecticide that has been used worldwide for agriculture and public health.
18920	glyphosate metabolic process	P	The chemical reactions and pathways involving glyphosate, a broad-spectrum herbicide also known by the trade name Roundup. It is a member of a broad class of compounds known as phosphonic acids, which contain a direct carbon-to-phosphorus (C-P) bond.
18921	3-hydroxybenzyl alcohol metabolic process	P	The chemical reactions and pathways involving 3-hydroxybenzyl alcohol, an aromatic compound which is an intermediate in several metabolic pathways, including the biosynthesis of patulin, a toxin and antiviral agent produced by some moulds such as Penicillium patulinum.
18922	iprodione metabolic process	P	The chemical reactions and pathways involving prodione, a colorless, odorless crystal. It is used as a dicarboximide contact fungicide to control a wide variety of crop diseases by inhibiting the germination of spores and the growth of the fungal mat (mycelium).
18923	limonene metabolic process	P	The chemical reactions and pathways involving limonene (4-isopropenyl-1-methyl-cyclohexene), a monocyclic monoterpene.
18924	mandelate metabolic process	P	The chemical reactions and pathways involving mandelate, the anion of mandelic acid. Mandelic acid (alpha-hydroxybenzeneacetic acid) is an 8-carbon alpha-hydroxy acid (AHA) that is used in organic chemistry and as a urinary antiseptic.
18925	m-cresol metabolic process	P	The chemical reactions and pathways involving m-cresol (3-hydroxytoluene), the meta-isoform of cresol. Used to produce agricultural chemicals, and in specialty resins, pharmaceuticals and pressure-sensitive dyes.
18926	methanesulfonic acid metabolic process	P	The chemical reactions and pathways involving methanesulfonic acid, a strong acid produced by the oxidation of dimethyl sulfide.
18928	methyl ethyl ketone metabolic process	P	The chemical reactions and pathways involving methyl ethyl ketone, a clear, colorless liquid with a fragrant, mint-like odor. It is used as a solvent and in making plastics, textiles and paints.
18929	methyl fluoride metabolic process	P	The chemical reactions and pathways involving methyl fluoride, fluorine-substituted methane, a gaseous halogenated hydrocarbon that has been investigated as an inhibitor of methanotrophy and nitrification in soils.
18930	3-methylquinoline metabolic process	P	The chemical reactions and pathways involving 3-methylquinoline, C10H9N, an aromatic compound composed of a benzene ring and a heterocyclic N-containing ring.
18931	naphthalene metabolic process	P	The chemical reactions and pathways involving naphthalene, a fused ring bicyclic aromatic hydrocarbon commonly found in crude oil and oil products. Naphthalene is familiar as the compound that gives mothballs their odor; it is used in the manufacture of plastics, dyes, solvents, and other chemicals, as well as being used as an antiseptic and insecticide.
18933	nicotine metabolic process	P	The chemical reactions and pathways involving nicotine, (S)(-)-3-(1-methyl-2-pyrrolidinyl)pyridine.
18934	nitrilotriacetate metabolic process	P	The chemical reactions and pathways involving nitrilotriacetate, an aminotricarboxylic acid that binds bivalent metal ions in a ratio of 1:1. As an important industrial chelating agent, NTA has been widely used for various radionuclide processing and decontamination procedures, such as textile, paper and pulp processing and water treatment.
18935	aerobic nitrilotriacetate metabolic process	P	The chemical reactions and pathways involving nitrilotriacetate, the aminotricarboxylic acid N(CH2COO-)3, that occur in the presence of oxygen.
18936	anaerobic nitrilotriacetate metabolic process	P	The chemical reactions and pathways involving nitrilotriacetate, the aminotricarboxylic acid N(CH2COO-)3, that occur in the absence of oxygen.
18937	nitroglycerin metabolic process	P	The chemical reactions and pathways involving nitroglycerin, a well-known nitrate ester and an important component of dynamite and other propellants. Toxic to algae, invertebrate, and vertebrates.
18938	2-nitropropane metabolic process	P	The chemical reactions and pathways involving 2-nitropropane, a clear, colorless liquid with a mild, fruity odor. 2-nitropropane is used principally as a solvent and chemical intermediate. As a solvent, it is used in inks, paints, adhesives, varnishes, polymers, and synthetic materials. It is a feedstock for the manufacture of 2-nitro-2-methyl-1-propanol and 2-amino-2-methyl-1-propanol.
18939	n-octane metabolic process	P	The chemical reactions and pathways involving n-octane, the 8 carbon straight chain alkane used in organic syntheses, calibrations, and azeotropic distillations. It is a common component of gasoline and other petroleum products and the engine fuel antiknocking properties of an isomer of n-octane are used as a comparative standard in the Octane Rating System.
18940	orcinol metabolic process	P	The chemical reactions and pathways involving orcinol (5-methyl-1,3-benzenediol), an aromatic compound derived from the fermentation of lichen, and synthesized, probably as a fungicide, by some higher plants.
18941	organomercury metabolic process	P	The chemical reactions and pathways involving organomercury compound, any organic compound containing a mercury atom.
18942	organometal metabolic process	P	The chemical reactions and pathways involving organometals, any metal-containing organic compound, especially one in which the metal atom is linked directly to one of more carbon atoms.
18943	organotin metabolic process	P	The chemical reactions and pathways involving organotin, an organic compound containing a tin atom.
18944	tri-n-butyltin metabolic process	P	The chemical reactions and pathways involving tri-n-butyltin, an organometallic compound composed of three butyl chains attached to a tin atom. Tri-n-butyltin is used as an antifouling agent in ship bottom paints and can be toxic to many marine organisms.
18945	organosilicon metabolic process	P	The chemical reactions and pathways involving any organosilicon, organic compounds that contain silicon, a nonmetal element analogous to carbon.
18946	aerobic organosilicon metabolic process	P	The chemical reactions and pathways involving organosilicons, organic compounds that contain silicon, in the presence of oxygen.
18947	anaerobic organosilicon metabolic process	P	The chemical reactions and pathways involving organosilicons, organic compounds that contain silicon, in the absence of oxygen.
18948	xylene metabolic process	P	The chemical reactions and pathways involving xylene, a mixture of three colorless, aromatic hydrocarbon liquids, ortho-, meta- and para-xylene.
18949	m-xylene metabolic process	P	The chemical reactions and pathways involving m-xylene, (1,3-dimethylbenzene) a colorless, liquid aromatic hydrocarbon.
18950	o-xylene metabolic process	P	The chemical reactions and pathways involving o-xylene, (1,2-dimethylbenzene) a colorless, liquid aromatic hydrocarbon.
18951	p-xylene metabolic process	P	The chemical reactions and pathways involving p-xylene, (1,4-dimethylbenzene) a colorless, liquid aromatic hydrocarbon.
18952	parathion metabolic process	P	The chemical reactions and pathways involving parathion, a highly toxic organophosphate compound formerly used as a broad spectrum insecticide, acaricide, fumigant and nematocide. Degradation of parathion by sunlight or liver enzymes can result in the formation of the active compound paraoxon which interferes with the nervous system through cholinesterase inhibition.
18953	p-cymene metabolic process	P	The chemical reactions and pathways involving p-cymene, 1-methyl-4-isopropylbenzene, one of the alkyl-substituted aromatic hydrocarbons found in volatile oils from over 100 plants.
18954	pentaerythritol tetranitrate metabolic process	P	The chemical reactions and pathways involving pentaerythritol tetranitrate, C(CH2-O-NO2)4, a substance produced for use as an explosive and a vasodilator.
18955	phenanthrene metabolic process	P	The chemical reactions and pathways involving phenanthrene, a tricyclic aromatic hydrocarbon used in explosives and in the synthesis of dyes and drugs. Although phenanthrene is not mutagenic or carcinogenic, it has been shown to be toxic to marine diatoms, gastropods, mussels, crustaceans, and fish.
18956	phenanthrene catabolic process via trans-9(R),10(R)-dihydrodiolphenanthrene	P	The chemical reactions and pathways resulting in the breakdown of phenanthrene, a tricyclic aromatic hydrocarbon, where trans-9(R),10(R)-dihydrodiolphenanthrene is the principal intermediate metabolite.
18957	phenanthrene catabolic process via trans-9(S),10(S)-dihydrodiolphenanthrene	P	The chemical reactions and pathways resulting in the breakdown of phenanthrene, a tricyclic aromatic hydrocarbon, where trans-9(S),10(S)-dihydrodiolphenanthrene is the principal intermediate metabolite.
18958	phenol-containing compound metabolic process	P	The chemical reactions and pathways involving a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring.
18959	aerobic phenol-containing compound metabolic process	P	The chemical reactions and pathways involving a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring, in the presence of oxygen.
18960	4-nitrophenol metabolic process	P	The chemical reactions and pathways involving 4-nitrophenol, a nitroaromatic compound which is used in the production of dyes, leather treatment agents, fungicides and as an intermediate in the production of the insecticide parathion.
18961	pentachlorophenol metabolic process	P	The chemical reactions and pathways involving pentachlorophenol, a chlorinated insecticide and fungicide used primarily to protect timber from fungal rot and wood boring insects. Pentachlorophenol is significantly toxic to mammals, plants, and many microorganisms.
18962	3-phenylpropionate metabolic process	P	The chemical reactions and pathways involving 3-phenylpropionate, the anion of phenylpropanoic acid. It is produced from putrefaction of proteins in soil or breakdown of several constituents of plants, such as lignin, various oils and resins.
18963	phthalate metabolic process	P	The chemical reactions and pathways involving phthalate, the anion of phthalic acid. Phthalic acid diesters are used industrially in the production of a variety of household and consumer goods including plastic polymers, lubricating oils, and carriers for perfumes in cosmetics, while phthalic acid itself is used industrially as a plasticizer. Terephthalate is used in the synthesis of polyethylene terephthalate (polyethene terephthlate, abbreviated PET or PETE), a plastic polymer with many commercial uses.
18964	propylene metabolic process	P	The chemical reactions and pathways involving propylene, an alkene produced by catalytic or thermal cracking of hydrocarbons or as a by-product of petroleum refining. It is used mainly in the preparation of alkylates for gasoline and in the production of polypropylene, acrylonitrile, propylene oxide and a number of other industrial chemicals.
18965	s-triazine compound metabolic process	P	The chemical reactions and pathways involving any s-triazine compound. These compounds include many pesticides of widespread use in agriculture, and are characterized by a symmetrical hexameric ring consisting of alternating carbon and nitrogen atoms.
18966	styrene metabolic process	P	The chemical reactions and pathways involving styrene, an aromatic hydrocarbon liquid soluble in ether and alcohol. When heated, exposed to light or added to a peroxide catalyst, it undergoes polymerization to form polystyrene, a versatile material used in the manufacture of plastics, synthetic rubber, thermal insulation, and packaging. Styrene is a classified mutagen and a suspected carcinogen.
18967	tetrachloroethylene metabolic process	P	The chemical reactions and pathways involving tetrachloroethylene (tetrachloroethene), a derivative of ethene with the hydrogen atoms replaced by chlorines. Tetrachloroethene has been used primarily as a solvent in dry-cleaning industries and to a lesser extent as a degreasing solvent.
18968	tetrahydrofuran metabolic process	P	The chemical reactions and pathways involving tetrahydrofuran, a cyclic 4 carbon ether. It is one of the most polar ethers and is a widely used solvent for polar reagents. Since THF is very soluble in water and has a relatively low boiling point, significant amounts are often released into the environment, causing contamination problems.
18969	thiocyanate metabolic process	P	The chemical reactions and pathways involving thiocyanate, the anion of thiocyanic acid, a toxic cyanide derivative commonly formed as a by-product in the production of gas for fuel, coke, and substances for chemical industries.
18970	toluene metabolic process	P	The chemical reactions and pathways involving toluene, a volatile monoaromatic hydrocarbon found in crude petroleum and petroleum products such as gasoline and commonly used as a paint thinning agent and in other solvent applications.
18971	anaerobic toluene metabolic process	P	The chemical reactions and pathways involving toluene, a volatile monoaromatic hydrocarbon found in crude petroleum and petroleum products, that occur in the absence of oxygen.
18972	toluene-4-sulfonate metabolic process	P	The chemical reactions and pathways involving toluene-4-sulfonate, the anion of 4-toluene sulfonic acid, a white crystalline solid which is highly hygroscopic and soluble in water.
18973	trinitrotoluene metabolic process	P	The chemical reactions and pathways involving trinitrotoluene, a methylated benzene molecule with three NO2 groups attached to it. This includes the explosive TNT, 1-methyl-2,4,6-trinitrobenzene.
18974	2,4,6-trinitrotoluene metabolic process	P	The chemical reactions and pathways involving 2,4,6-trinitrotoluene, 1-methyl-2,4,6-trinitrobenzene, a highly explosive pale yellow crystalline solid. It is prepared from toluene treated with concentrated sulfuric and nitric acids and is used in shells, bombs, and blasting explosives.
18975	anaerobic 2,4,6-trinitrotoluene metabolic process	P	The chemical reactions and pathways involving 2,4,6-trinitrotoluene, 1-methyl-2,4,6-trinitrobenzene, a highly explosive pale yellow crystalline solid, that occur in the absence of oxygen.
18976	1,2,3-tribromopropane metabolic process	P	The chemical reactions and pathways involving 1,2,3-tribromopropane, a toxic and volatile organic compound commonly used as a nematocide in agriculture.
18977	1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane metabolic process	P	The chemical reactions and pathways involving 1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane (DDT), a chlorinated broad spectrum contact insecticide.
18978	anaerobic 1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane metabolic process	P	The chemical reactions and pathways involving 1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane (DDT), a chlorinated, broad spectrum, contact insecticide, in the absence of oxygen.
18979	trichloroethylene metabolic process	P	The chemical reactions and pathways involving trichloroethylene, a toxic, colorless, photoreactive, chlorinated hydrocarbon liquid, commonly used as a metal degreaser and solvent.
18980	2,4,5-trichlorophenoxyacetic acid metabolic process	P	The chemical reactions and pathways involving 2,4,5-trichlorophenoxyacetic acid, a chlorinated aromatic compound which is widely used as a herbicide, often as a weed killer for home lawns.
18981	triethanolamine metabolic process	P	The chemical reactions and pathways involving triethanolamine, a combustible, hygroscopic, colorless liquid commonly used in dry-cleaning solutions, cosmetics, detergents, textile processing, wool scouring, and as a corrosion inhibitor and pharmaceutical alkalizing agent.
18982	vanillin metabolic process	P	The chemical reactions and pathways involving vanillin, an aromatic hydrocarbon which occurs naturally in black vanilla bean pods and can be obtained as a by-product of the pulp and paper industry by the oxidative breakdown of lignin.
18983	Z-phenylacetaldoxime metabolic process	P	The chemical reactions and pathways involving Z-phenylacetaldoxime, a member of the glucosinolate group of compounds, a class of natural products that are gaining increasing interest as cancer-preventing agents and crop protectants.
18984	naphthalenesulfonate metabolic process	P	The chemical reactions and pathways involving naphthalenesulfonate, sulfonated derivatives of naphthalene.
18985	pronuclear envelope synthesis	P	Synthesis and ordering of the envelope of pronuclei.
18989	apolysis	P	The first process of molting, characterized by the detachment of the old cuticle from the underlying epidermal cells.
18990	ecdysis, chitin-based cuticle	P	The shedding of the old chitin-based cuticlar fragments during the molting cycle. An example of this is found in Drosophila melanogaster.
18991	oviposition	P	The deposition of eggs (either fertilized or not) upon a surface or into a medium such as water.
18992	germ-line sex determination	P	The determination of sex and sexual phenotype in an organism's germ line.
18993	somatic sex determination	P	The determination of sex and sexual phenotypes in an organism's soma.
18995	host	C	Any organism in which another organism, especially a parasite or symbiont, spends part or all of its life cycle and from which it obtains nourishment and/or protection.
18996	molting cycle, collagen and cuticulin-based cuticle	P	The periodic shedding of part or all of a collagen and cuticulin-based cuticle, which is then replaced by a new collagen and cuticulin-based cuticle. An example of this is found in the Nematode worm, Caenorhabditis elegans.
19001	guanyl nucleotide binding	F	Interacting selectively and non-covalently with guanyl nucleotides, any compound consisting of guanosine esterified with (ortho)phosphate.
19002	GMP binding	F	Interacting selectively and non-covalently with GMP, guanosine monophosphate.
19003	GDP binding	F	Interacting selectively and non-covalently with GDP, guanosine 5'-diphosphate.
19005	SCF ubiquitin ligase complex	C	A ubiquitin ligase complex in which a cullin from the Cul1 subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by a Skp1 adaptor and an F-box protein. SCF complexes are involved in targeting proteins for degradation by the proteasome. The best characterized complexes are those from yeast and mammals (with core subunits named Cdc53/Cul1, Rbx1/Hrt1/Roc1).
19008	molybdopterin synthase complex	C	A protein complex that possesses molybdopterin synthase activity. In E. coli, the complex is a heterotetramer consisting of two MoaD and two MoaE subunits.
19010	farnesoic acid O-methyltransferase activity	F	Catalysis of the reaction: farnesoic acid + S-adenosyl-methionine = methyl farnesoate + S-adenosyl-L-homocysteine.
19012	virion	C	The complete fully infectious extracellular virus particle.
19013	viral nucleocapsid	C	The complete protein-nucleic acid complex that is the packaged form of the genome in a virus particle.
19015	viral genome	C	The whole of the genetic information of a virus, contained as either DNA or RNA.
19016	non-segmented viral genome	C	A viral genome that consists of one continuous nucleic acid molecule.
19017	segmented viral genome	C	A viral genome that is divided into two or more physically separate molecules of nucleic acid and packaged into a single virion.
19018	bipartite viral genome	C	A segmented viral genome consisting of two sub-genomic nucleic acids but each nucleic acid is packaged into a different virion.
19019	tripartite viral genome	C	A segmented viral genome consisting of three sub-genomic nucleic acids but each nucleic acid is packaged into a different virion.
19020	multipartite viral genome	C	A segmented viral genome consisting of more than three sub-genomic nucleic acids but each nucleic acid is packaged into a different virion.
19021	DNA viral genome	C	A viral genome composed of deoxyribonucleic acid.
19022	RNA viral genome	C	A viral genome composed of ribonucleic acid. This results in genome replication and expression of genetic information being inextricably linked.
19023	dsRNA viral genome	C	A viral genome composed of double stranded RNA.
19024	ssRNA viral genome	C	A viral genome composed of single stranded RNA of either positive or negative sense.
19025	positive sense viral genome	C	A single stranded RNA genome with the same nucleotide polarity as mRNA.
19026	negative sense viral genome	C	A single stranded RNA genome with the opposite nucleotide polarity as mRNA.
19027	ambisense viral genome	C	A RNA genome that contains coding regions that are either positive sense or negative sense on the same RNA molecule.
19028	viral capsid	C	The protein coat that surrounds the infective nucleic acid in some virus particles. It comprises numerous regularly arranged subunits, or capsomeres.
19029	helical viral capsid	C	The protein coat that surrounds the infective nucleic acid in some virus particles; the subunits are arranged to form a protein helix with the genetic material contained within. Tobacco mosaic virus has such a capsid structure.
19030	icosahedral viral capsid	C	The protein coat that surrounds the infective nucleic acid in some virus particles; the subunits are arranged to form an icosahedron, a solid with 20 faces and 12 vertices. Icosahedral capsids have 12 pentamers plus 10(T-1) hexamers, where T is the triangulation number. Tobacco satellite necrosis virus has such a capsid structure.
19031	viral envelope	C	The lipid bilayer of a virion that surrounds the protein capsid. May also contain glycoproteins.
19033	viral tegument	C	A structure lying between the capsid and envelope of a virus, varying in thickness and often distributed asymmetrically.
19034	viral replication complex	C	Specific locations and structures in the virus infected cell involved in replicating the viral genome.
19035	viral integration complex	C	A nucleoprotein complex containing viral genetic material and associated viral and host proteins, which is capable of inserting a viral genome into a host genome.
19036	viral transcriptional complex	C	Specific locations and structures in the virus infected cell involved in transcribing the viral genome.
19037	viral assembly intermediate	C	Specific locations and structures in the virus infected cell involved in assembling new virions.
19038	provirus	C	The name given to a viral genome after it has been integrated into the host genome; particularly applies to retroviruses and is a required part of the retroviral replication cycle.
19042	viral latency	P	The process by which, after initial infection, a virus lies dormant within a cell and viral production ceases. The process ends when the virus switches from latency and starts to replicate.
19043	establishment of viral latency	P	A process by which a virus establishes a latent state within its host, either as an integrated provirus within the host genome or as an episome, where viral genome remains in the cytoplasm or nucleus as distinct objects.
19044	maintenance of viral latency	P	The perpetuation of a latent state, generally by repressing the viruses own lytic genes expression and ensuring expression of viral genes which function to keep the viral genome from being detected by the host defense mechanisms.
19045	latent virus replication	P	Any process required for latent viral replication in a cell.
19046	release from viral latency	P	The process by which a virus switches from latency and begins to replicate. It may be effected by various endogenous and exogenous stimuli, including B-cell lipopolysaccharides, glucocorticoid hormones, halogenated pyrimidines, ionizing radiation, ultraviolet light, various chemicals and super-infecting viruses.
19048	modulation by virus of host morphology or physiology	P	The process in which a virus effects a change in the structure or processes of its host organism.
19049	evasion or tolerance of host defenses by virus	P	Any process, either active or passive, by which a virus avoids or tolerates the effects of its host organism's defense(s). Host defenses may be induced by the presence of the virus or may be preformed (e.g. physical barriers). The host is defined as the larger of the organisms involved in a symbiotic interaction.
19050	suppression by virus of host apoptotic process	P	Any viral process that inhibits apoptosis of infected host cells, facilitating prolonged cell survival during viral replication.
19051	induction by virus of host apoptotic process	P	The set of viral processes that induce an apoptotic process in infected host cells, facilitating release and spread of progeny virions.
19054	modulation by virus of host process	P	The process in which a virus effects a change in the processes and activities of its host organism.
19055	modification by virus of host cell cycle regulation	P	Interactions, directly with the host cell macromolecular machinery, to allow a virus to modulate the rate of the host cell cycle to facilitate virus replication.
19056	modulation by virus of host transcription	P	Any process in which a virus modulates the frequency, rate or extent of its host's transcription.
19057	modulation by virus of host translation	P	Any process in which a virus modulates the frequency, rate or extent of translation of host mRNA.
19058	viral life cycle	P	A set of processes which all viruses follow to ensure survival; includes attachment and entry of the virus particle, decoding of genome information, translation of viral mRNA by host ribosomes, genome replication, and assembly and release of viral particles containing the genome.
19060	intracellular transport of viral protein in host cell	P	The directed movement of a viral protein within the host cell.
19061	uncoating of virus	P	The process by which an incoming virus is disassembled in the host cell to release a replication-competent viral genome.
19062	virion attachment to host cell	P	The process by which a virion protein binds to molecules on the host cellular surface or host cell surface projection.
19064	fusion of virus membrane with host plasma membrane	P	Fusion of a viral membrane with the host cell membrane during viral entry. Results in release of the virion contents into the cytoplasm.
19065	receptor-mediated endocytosis of virus by host cell	P	Any receptor-mediated endocytosis that is involved in the uptake of a virus into a host cell; successive instances of virus endocytosis result in the accumulation of virus particles within the cell.
19068	virion assembly	P	A late phase of the viral life cycle during which all the components necessary for the formation of a mature virion collect at a particular site in the cell and the basic structure of the virus particle is formed.
19069	viral capsid assembly	P	The assembly of a virus capsid from its protein subunits.
19070	viral genome maturation	P	The processes involved in creating a mature, stable viral genome. Begins after genome replication with a newly synthesized nucleic acid and ends when the genome is ready to be packaged. Includes the addition of proteins to the newly synthesized genome, and DNA repair processes.
19071	viral DNA cleavage involved in viral genome maturation	P	The cleavage of viral DNA into singular functional units.
19072	viral genome packaging	P	The encapsulation of the viral genome within the capsid.
19073	viral DNA genome packaging	P	The packing of viral DNA into a capsid.
19074	viral RNA genome packaging	P	The packaging of viral RNA (single-stranded or double-stranded) into a nucleocapsid.
19075	virus maturation	P	The refolding and structural rearrangements of virion parts to transition from the intermediate virion to the more mature virion. Maturation usually involves proteolysis events and changes in the folding of the virion proteins. Can occur inside the host cell or after release.
19076	viral release from host cell	P	The dissemination of mature viral particles from the host cell, e.g. by cell lysis or the budding of virus particles from the cell membrane.
19079	viral genome replication	P	Any process involved directly in viral genome replication, including viral nucleotide metabolism.
19080	viral gene expression	P	A process by which a viral gene is converted into a mature gene product or products (proteins or RNA). This includes viral transcription, processing to produce a mature RNA product, and viral translation.
19081	viral translation	P	A process by which viral mRNA is translated into viral protein, using the host cellular machinery.
19082	viral protein processing	P	Any protein maturation process achieved by the cleavage of a peptide bond or bonds within a viral protein.
19083	viral transcription	P	The process by which a viral genome, or part of a viral genome, is transcribed within the host cell.
19084	middle viral transcription	P	The viral transcription that takes place after early transcription in the viral life cycle, and which involves the transcription of genes required for replication.
19085	early viral transcription	P	The first phase of viral transcription that occurs after entry of the virus into the host cell, but prior to viral genome replication. It involves the transcription of genes for non-structural proteins, and for lytic viruses, the early gene products are involved in establishing control over the host cell.
19086	late viral transcription	P	The transcription of the final group of viral genes of the viral life cycle, following middle transcription, or where middle transcription doesn't occur, following early transcription. Involves the transcription of genes encoding structural proteins.
19087	transformation of host cell by virus	P	Any virus-induced change in the morphological, biochemical, or growth parameters of a cell.
19088	immortalization of host cell by virus	P	A virus-induced cellular transformation arising in immortalized cells, or cells capable of indefinite replication, due to their ability to produce their own telomerase.
19089	transmission of virus	P	The transfer of virions in order to create new infection.
19090	mitochondrial rRNA export from mitochondrion	P	The directed movement of mitochondrial rRNA out of a mitochondrion.
19091	mitochondrial lrRNA export from mitochondrion	P	The directed movement of mitochondrial lrRNA out of a mitochondrion.
19092	mitochondrial srRNA export from mitochondrion	P	The directed movement of mitochondrial srRNA out of a mitochondrion.
19093	mitochondrial RNA localization	P	Any process in which mitochondrial RNA is transported to, or maintained in, a specific location.
19094	pole plasm mRNA localization	P	Any process in which mRNA is transported to, or maintained in, the oocyte pole plasm. An example of this is found in Drosophila melanogaster.
19095	pole plasm mitochondrial rRNA localization	P	Any process in which mitochondrial ribosomal RNA is transported to, or maintained in, the oocyte pole plasm. An example of this is found in Drosophila melanogaster.
19096	pole plasm mitochondrial lrRNA localization	P	Any process in which mitochondrial large ribosomal RNA is transported to, or maintained in, the oocyte pole plasm. An example of this is found in Drosophila melanogaster.
19097	pole plasm mitochondrial srRNA localization	P	Any process in which mitochondrial small ribosomal RNA is transported to, or maintained in, the oocyte pole plasm. An example of this is found in Drosophila melanogaster.
19098	reproductive behavior	P	The specific behavior of an organism that is associated with reproduction.
19099	female germ-line sex determination	P	The determination of sex and sexual phenotype in a female organism's germ line.
19100	male germ-line sex determination	P	The determination of sex and sexual phenotype in a male organism's germ line.
19101	female somatic sex determination	P	The determination of sex and sexual phenotypes in a female organism's soma.
19102	male somatic sex determination	P	The determination of sex and sexual phenotypes in a male organism's soma.
19103	pyrimidine nucleotide binding	F	Interacting selectively and non-covalently with pyrimidine nucleotide, any compound consisting of a pyrimidine nucleoside esterified with (ortho)phosphate.
19104	DNA N-glycosylase activity	F	Catalysis of the removal of damaged bases by cleaving the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar. The reaction releases a free base and leaves an apurinic/apyrimidinic (AP) site.
19105	N-palmitoyltransferase activity	F	Catalysis of the transfer of a palmitoyl group to a nitrogen atom on the acceptor molecule.
19107	myristoyltransferase activity	F	Catalysis of the transfer of a myristoyl (CH3-[CH2]12-CO-) group to an acceptor molecule.
19108	aryl-aldehyde dehydrogenase (NAD) activity	F	Catalysis of the reaction: an aromatic aldehyde + NAD+ + H2O = an aromatic acid + NADH + H+.
19111	phenanthrol sulfotransferase activity	F	Catalysis of the reaction: phenanthrol + X-SO3(-) = HX + phenanthrylsulfate.
19112	phenanthrol glycosyltransferase activity	F	Catalysis of the reaction: phenanthrol + glucose = phenanthryl-beta-D-glucopyranoside + H2O.
19113	limonene monooxygenase activity	F	Catalysis of a monooxygenase reaction in which oxygen is incorporated into limonene.
19114	catechol dioxygenase activity	F	Catalysis of the reaction: catechol + O2 = a muconate.
19115	benzaldehyde dehydrogenase activity	F	Catalysis of the reaction: benzaldehyde + NAD(P)+ + H2O = benzoate + NAD(P)H + H+.
19116	hydroxy-nicotine oxidase activity	F	Catalysis of the reaction: 6-hydroxynicotine + H2O + O2 = 1-(6-hydroxypyrid-3-yl)-4-(methylamino)butan-1-one + hydrogen peroxide.
19117	dihydroxyfluorene dioxygenase activity	F	Catalysis of the reaction: a dihydroxyfluorene + O2 = the corresponding 2-hydroxy-4-(oxo-1,3-dihydro-2H-inden-ylidene) but-2-enoic acid.
19118	phenanthrene-epoxide hydrolase activity	F	Catalysis of the reaction: a phenanthrene dioxide + H2O = a dihydrodiolphenanthrene.
19119	phenanthrene-9,10-epoxide hydrolase activity	F	Catalysis of the reaction: phenanthrene-9,10-oxide + H2O = trans-9,10-dihydrodiolphenanthrene.
19120	hydrolase activity, acting on acid halide bonds, in C-halide compounds	F	Catalysis of the hydrolysis of any acid halide bond in substances containing halogen atoms in organic linkage.
19121	peptidoglycan-protein cross-linking via N6-mureinyl-L-lysine	P	The process of linking a protein to peptidoglycan via the epsilon amino group of lysine to the diaminopimelic acid of the peptidoglycan.
19122	peptidyl-D-alanine racemization	P	The formation of peptidyl-D-alanine, by either racemization or from peptidyl-L-serine.
19123	peptidyl-methionine racemization	P	The racemization of peptidyl-methionine.
19124	peptidyl-isoleucine racemization	P	The racemization of peptidyl-isoleucine.
19125	peptidyl-phenylalanine racemization	P	The racemization of peptidyl-phenylalanine.
19126	peptidyl-serine racemization	P	The racemization of peptidyl-serine.
19128	peptidyl-tryptophan racemization	P	The racemization of peptidyl-tryptophan.
19129	peptidyl-leucine racemization	P	The racemization of peptidyl-leucine.
19133	choline monooxygenase activity	F	Catalysis of the reaction: choline + 2 reduced ferredoxin + O2 + 2 H+ = betaine aldehyde hydrate + 2 oxidized ferredoxin + H2O.
19134	glucosamine-1-phosphate N-acetyltransferase activity	F	Catalysis of the reaction: alpha-D-glucosamine 1-phosphate + acetyl-CoA = N-acetyl-alpha-D-glucosamine 1-phosphate + CoA + H(+).
19135	deoxyhypusine monooxygenase activity	F	Catalysis of the reaction: protein N6-(4-aminobutyl)-L-lysine + donor-H2 + O2 = protein N6-((R)-4-amino-2-hydroxybutyl)-L-lysine + acceptor + H2O.
19136	deoxynucleoside kinase activity	F	Catalysis of the reaction: ATP + 2'-deoxynucleoside = ADP + 2'-deoxynucleoside 5'-phosphate.
19137	thioglucosidase activity	F	Catalysis of the reaction: a thioglucoside + H2O = a thiol + a sugar.
19139	cytokinin dehydrogenase activity	F	Catalysis of the reaction: N6-dimethylallyladenine + acceptor + H2O = adenine + 3-methylbut-2-enal + reduced electron acceptor.
19140	inositol 3-kinase activity	F	Catalysis of the reaction: ATP + myo-inositol = ADP + 1D-myo-inositol 3-phosphate.
19141	2-dehydropantolactone reductase (B-specific) activity	F	Catalysis of the reaction: (R)-pantolactone + NADP+ = 2-dehydropantolactone + NADPH + H+. The reaction is B-specific (i.e. the pro-S hydrogen is transferred from the 4-position of reduced nicotinamide cofactor) with respect to NADP+.
19142	2-hydroxyglutarate synthase activity	F	Catalysis of the reaction: glyoxylate + H(2)O + propanoyl-CoA = 2-hydroxyglutarate + CoA + H(+).
19143	3-deoxy-manno-octulosonate-8-phosphatase activity	F	Catalysis of the reaction: 8-phospho-3-deoxy-D-manno-oct-2-ulosonate + H(2)O = 3-deoxy-D-manno-octulosonate + phosphate.
19144	ADP-sugar diphosphatase activity	F	Catalysis of the reaction: ADP-sugar + H2O = AMP + sugar 1-phosphate.
19145	aminobutyraldehyde dehydrogenase activity	F	Catalysis of the reaction: 4-aminobutanal + NAD+ + H2O = 4-aminobutanoate + NADH + 2 H+.
19146	arabinose-5-phosphate isomerase activity	F	Catalysis of the reaction: D-arabinose 5-phosphate = D-ribulose 5-phosphate + 2 H(+).
19147	(R)-aminopropanol dehydrogenase activity	F	Catalysis of the reaction: (R)-1-aminopropan-2-ol + NAD(+) = aminoacetone + H(+) + NADH.
19148	D-cysteine desulfhydrase activity	F	Catalysis of the reaction: D-cysteine + H2O = sulfide + NH3 + pyruvate.
19149	3-chloro-D-alanine dehydrochlorinase activity	F	Catalysis of the reaction: 3-chloro-D-alanine + H2O = pyruvate + chloride + NH3.
19150	D-ribulokinase activity	F	Catalysis of the reaction: ATP + D-ribulose = ADP + D-ribulose 5-phosphate.
19151	galactose 1-dehydrogenase activity	F	Catalysis of the reaction: D-galactose + NAD+ = D-galactono-1,4-lactone + NADH + H+.
19152	acetoin dehydrogenase activity	F	Catalysis of the reaction: acetoin + NAD+ = diacetyl + NADH + H+.
19153	protein-disulfide reductase (glutathione) activity	F	Catalysis of the reaction: 2 glutathione + protein-disulfide = oxidized glutathione + protein-dithiol.
19154	glycolate dehydrogenase activity	F	Catalysis of the reaction: A + glycolate = AH(2) + glyoxylate.
19155	3-(imidazol-5-yl)lactate dehydrogenase activity	F	Catalysis of the reaction: (S)-3-(imidazol-5-yl)lactate + NADP+ = 3-(imidazol-5-yl)pyruvate + NADPH + H+.
19156	isoamylase activity	F	Catalysis of the hydrolysis of alpha-(1,6)-D-glucosidic branch linkages in glycogen, amylopectin and their beta-limits dextrins.
19157	malate oxidase activity	F	Catalysis of the reaction: (S)-malate + O(2) = H(2)O(2) + oxaloacetate.
19158	mannokinase activity	F	Catalysis of the reaction: ATP + D-mannose = ADP + D-mannose 6-phosphate.
19159	nicotinamide-nucleotide amidase activity	F	Catalysis of the reaction: beta-nicotinamide D-ribonucleotide + H2O = beta-nicotinate D-ribonucleotide + NH3.
19160	NMN nucleosidase activity	F	Catalysis of the reaction: H(2)O + nicotinamide mononucleotide = D-ribose 5-phosphate + H(+) + nicotinamide.
19161	diamine transaminase activity	F	Catalysis of the reaction: an alpha,omega-diamine + 2-oxoglutarate = an omega-aminoaldehyde + L-glutamate.
19162	pyridoxamine-oxaloacetate transaminase activity	F	Catalysis of the reaction: oxaloacetate + pyridoxamine = L-aspartate + pyridoxal.
19163	pyridoxamine-phosphate transaminase activity	F	Catalysis of the reaction: pyridoxamine 5'-phosphate + 2-oxoglutarate = pyridoxal 5'-phosphate + D-glutamate.
19164	pyruvate synthase activity	F	Catalysis of the reaction: pyruvate + CoA + 2 oxidized ferredoxin = acetyl-CoA + CO2 + 2 reduced ferredoxin + 2 H+.
19165	thiamine kinase activity	F	Catalysis of the reaction: ATP + thiamine = ADP + 2 H(+) + thiamine phosphate.
19166	trans-2-enoyl-CoA reductase (NADPH) activity	F	Catalysis of the reaction: acyl-CoA + NADP+ = trans-2,3-dehydroacyl-CoA + NADPH + H+.
19168	2-octaprenylphenol hydroxylase activity	F	Catalysis of the reaction: 2-octaprenylphenol + NADPH + O2 + H+ = 2-octaprenyl-6-hydroxyphenol + NADP+ + H2O.
19170	methylglyoxal reductase (NADH-dependent) activity	F	Catalysis of the reaction: (R)-lactaldehyde + NAD+ = methylglyoxal + NADH + H+.
19171	3-hydroxyacyl-[acyl-carrier-protein] dehydratase activity	F	Catalysis of the reaction: a (3R)-3-hydroxyacyl-[acyl-carrier protein] = H2O + a trans-delta2-enoyl-acyl-[acyl-carrier protein].
19172	glyoxalase III activity	F	Catalysis of the reaction: methylglyoxal + H2O = D-lactate.
19174	tetrahydrothiophene 1-oxide reductase activity	F	Catalysis of the reaction: tetrahydrothiophene 1-oxide + reduced acceptor = tetrahydrothiophene + acceptor.
19176	dihydroneopterin monophosphate phosphatase activity	F	Catalysis of the reaction: dihydroneopterin monophosphate = dihydroneopterin + phosphate.
19177	dihydroneopterin triphosphate pyrophosphohydrolase activity	F	Catalysis of the reaction: dihydroneopterin triphosphate = dihydroneopterin phosphate + diphosphate.
19178	NADP phosphatase activity	F	Catalysis of the reaction: H2O + NADP+ = NAD+ + phosphate.
19179	dTDP-4-amino-4,6-dideoxy-D-glucose transaminase activity	F	Catalysis of the reaction: dTDP-4-amino-4,6-dideoxy-D-glucose + 2-oxoglutarate = dTDP-4-dehydro-6-deoxy-D-glucose + L-glutamate.
19180	dTDP-4-amino-4,6-dideoxygalactose transaminase activity	F	Catalysis of the reaction: 2-oxoglutarate + dTDP-4-amino-4,6-dideoxy-D-galactose = L-glutamate + dTDP-4-dehydro-6-deoxy-D-galactose.
19181	halohydrin hydrogen-halide-lyase activity	F	Catalysis of the reaction: a halohydrin = an epoxide + a hydrogen halide.
19182	histamine-gated chloride channel activity	F	Enables the transmembrane transfer of a chloride ion by a channel that opens when histamine has been bound by the channel complex or one of its constituent parts.
19183	histamine-gated chloride channel complex	C	A protein complex that forms a transmembrane channel through which chloride ions may pass in response to histamine binding to the channel complex or one of its constituent parts.
19184	nonribosomal peptide biosynthetic process	P	The biosynthetic process in which peptide bond formation occurs in the absence of the translational machinery. Examples include the synthesis of antibiotic peptides, and glutathione.
19185	snRNA-activating protein complex	C	A protein complex that recognizes the proximal sequence element of RNA polymerase II and III snRNA promoters.
19186	acyl-CoA N-acyltransferase activity	F	Catalysis of the transfer of an acyl group from acyl-CoA to a nitrogen atom on an acceptor molecule.
19187	beta-1,4-mannosyltransferase activity	F	Catalysis of the transfer of a mannose residue to an oligosaccharide, forming a beta-(1->4) linkage.
19191	cellobiose transmembrane transporter activity	F	Enables the transfer of cellobiose from one side of the membrane to the other. Cellobiose, or 4-O-beta-D-glucopyranosyl-D-glucose, is a disaccharide that represents the basic repeating unit of cellulose.
19194	sorbose transmembrane transporter activity	F	Enables the transfer of sorbose from one side of the membrane to the other. Sorbose is the ketohexose xylo-2-hexulose; L-sorbose is formed by bacterial oxidation of sorbitol. Sorbose is produced commercially by fermentation and is used as an intermediate in the manufacture of ascorbic acid.
19196	galactosamine transmembrane transporter activity	F	Enables the transfer of galactosamine from one side of the membrane to the other. Galactosamine is an aminodeoxysugar; D-galactosamine is a constituent of some glycolipids and glycosaminoglycans, commonly as its N-acetyl derivative.
19197	phosphoenolpyruvate-dependent sugar phosphotransferase complex	C	Includes phosphoenolpyruvate-protein phosphatase (enzyme I of the phosphotransferase system) and protein-N(PI)-phosphohistidine-sugar phosphotransferase (enzyme II of the phosphotransferase system).
19198	transmembrane receptor protein phosphatase activity	F	Combining with a signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: a phosphoprotein + H2O = a protein + phosphate.
19199	transmembrane receptor protein kinase activity	F	Combining with a signal and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: a protein + ATP = a phosphoprotein + ADP.
19200	carbohydrate kinase activity	F	Catalysis of the transfer of a phosphate group, usually from ATP, to a carbohydrate substrate molecule.
19201	nucleotide kinase activity	F	Catalysis of the reaction: ATP + nucleoside monophosphate = ADP + nucleoside diphosphate.
19202	amino acid kinase activity	F	Catalysis of the transfer of a phosphate group, usually from ATP, to an amino acid substrate.
19203	carbohydrate phosphatase activity	F	Catalysis of the reaction: carbohydrate phosphate + H2O = carbohydrate + phosphate.
19205	nucleobase-containing compound kinase activity	F	Catalysis of the transfer of a phosphate group, usually from ATP or GTP, to a nucleobase, nucleoside, nucleotide or polynucleotide substrate.
19206	nucleoside kinase activity	F	Catalysis of the reaction: ATP + nucleoside = ADP + nucleoside monophosphate.
19207	kinase regulator activity	F	Modulates the activity of a kinase, an enzyme which catalyzes of the transfer of a phosphate group, usually from ATP, to a substrate molecule.
19208	phosphatase regulator activity	F	Modulates the activity of a phosphatase, an enzyme which catalyzes of the removal of a phosphate group from a substrate molecule.
19209	kinase activator activity	F	Binds to and increases the activity of a kinase, an enzyme which catalyzes of the transfer of a phosphate group, usually from ATP, to a substrate molecule.
19210	kinase inhibitor activity	F	Stops, prevents or reduces the activity of a kinase, an enzyme which catalyzes of the transfer of a phosphate group, usually from ATP, to a substrate molecule.
19211	phosphatase activator activity	F	Increases the activity of a phosphatase, an enzyme which catalyzes of the removal of a phosphate group from a substrate molecule.
19212	phosphatase inhibitor activity	F	Stops, prevents or reduces the activity of a phosphatase, an enzyme which catalyzes of the removal of a phosphate group from a substrate molecule.
19213	deacetylase activity	F	Catalysis of the hydrolysis of an acetyl group or groups from a substrate molecule.
19215	intermediate filament binding	F	Interacting selectively and non-covalently with an intermediate filament, a distinct elongated structure, characteristically 10 nm in diameter, that occurs in the cytoplasm of higher eukaryotic cells. Intermediate filaments form a fibrous system, composed of chemically heterogeneous subunits and involved in mechanically integrating the various components of the cytoplasmic space.
19216	regulation of lipid metabolic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving lipids.
19217	regulation of fatty acid metabolic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving fatty acids.
19218	regulation of steroid metabolic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving steroids.
19219	regulation of nucleobase-containing compound metabolic process	P	Any cellular process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids.
19220	regulation of phosphate metabolic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving phosphates.
19221	cytokine-mediated signaling pathway	P	A series of molecular signals initiated by the binding of a cytokine to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.
19222	regulation of metabolic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism.
19226	transmission of nerve impulse	P	The neurological system process in which a signal is transmitted through the nervous system by a combination of action potential propagation and synaptic transmission.
19227	neuronal action potential propagation	P	The propagation of an action potential along an axon, away from the soma.
19228	neuronal action potential	P	An action potential that occurs in a neuron.
19229	regulation of vasoconstriction	P	Any process that modulates the frequency, rate or extent of reductions in the diameter of blood vessels.
19230	proprioception	P	The series of events by which an organism senses the position, location, orientation, and movement of the body and its parts. Proprioception is mediated by proprioceptors, sensory nerve terminals found in muscles, tendons, and joint capsules, which give information concerning movements and position of the body. The receptors in the labyrinth are sometimes also considered proprioceptors.
19231	perception of static position	P	The perception of the orientation of different parts of the body with respect to one another.
19232	perception of rate of movement	P	The series of events by which an organism senses the speed and direction of movement of the body and its parts.
19233	sensory perception of pain	P	The series of events required for an organism to receive a painful stimulus, convert it to a molecular signal, and recognize and characterize the signal. Pain is medically defined as the physical sensation of discomfort or distress caused by injury or illness, so can hence be described as a harmful stimulus which signals current (or impending) tissue damage. Pain may come from extremes of temperature, mechanical damage, electricity or from noxious chemical substances. This is a neurological process.
19234	sensory perception of fast pain	P	The series of events required for an organism to receive a fast pain stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process. Fast pain is often subjectively described as a sharp or stabbing pain; in humans, the signals from a fast pain stimulus are perceived and relayed along myelinated A-delta fibers to the central nervous system, reaching their target in about 0.1 seconds.
19235	sensory perception of slow pain	P	The series of events required for an organism to receive a slow pain stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process. Slow pain is often subjectively described as an aching or throbbing pain; in humans, the signals from a slow pain stimulus are perceived and relayed along unmyelinated C fibers to the central nervous system, reaching their target in about 1 second. Slow pain is often associated with tissue destruction.
19236	response to pheromone	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pheromone stimulus.
19237	centromeric DNA binding	F	Interacting selectively and non-covalently with a centromere, a region of chromosome where the spindle fibers attach during mitosis and meiosis.
19238	cyclohydrolase activity	F	Catalysis of the hydrolysis of any non-peptide carbon-nitrogen bond in a cyclic amidine, a compound of the form R-C(=NH)-NH2, in a reaction that involves the opening of a ring.
19239	deaminase activity	F	Catalysis of the removal of an amino group from a substrate, producing ammonia (NH3).
19240	citrulline biosynthetic process	P	The chemical reactions and pathways resulting in the formation of citrulline, N5-carbamoyl-L-ornithine, an alpha amino acid not found in proteins.
19241	citrulline catabolic process	P	The chemical reactions and pathways resulting in the breakdown of citrulline, N5-carbamoyl-L-ornithine, an alpha amino acid not found in proteins.
19242	methylglyoxal biosynthetic process	P	The chemical reactions and pathways resulting in the formation of methylglyoxal, CH3-CO-CHO, the aldehyde of pyruvic acid.
19243	methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione	P	The chemical reactions and pathways resulting in the breakdown of methylglyoxal, CH3-CO-CHO, into D-lactate via the intermediate S-lactoyl-glutathione. Glutathione is used in the first step of the pathway and then regenerated in the second step.
19244	lactate biosynthetic process from pyruvate	P	The chemical reactions and pathways resulting in the formation of lactate from other compounds, including pyruvate.
19245	D(-)-lactate biosynthetic process from pyruvate	P	The chemical reactions and pathways resulting in the formation of D(-)-lactate from other compounds, including pyruvate.
19246	L(+)-lactate biosynthetic process from pyruvate	P	The chemical reactions and pathways resulting in the formation of L(+)-lactate from other compounds, including pyruvate.
19247	lactate racemization	P	Partial conversion of one lactate enantiomer into another so that the specific optical rotation is decreased, or even reduced to zero, in the resulting mixture.
19248	D-lactate biosynthetic process from methylglyoxal via (R)-lactaldehyde	P	The chemical reactions and pathways resulting in the formation of D-lactate from methylglyoxal, via the intermediate (R)-lactaldehyde.
19249	lactate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of lactate, the anion of lactic acid.
19250	aerobic cobalamin biosynthetic process	P	The chemical reactions and pathways resulting in the formation of cobalamin (vitamin B12) in the presence of oxygen.
19251	anaerobic cobalamin biosynthetic process	P	The chemical reactions and pathways resulting in the formation of cobalamin (vitamin B12) in the absence of oxygen.
19252	starch biosynthetic process	P	The chemical reactions and pathways resulting in the formation of starch, the most important reserve polysaccharide in plants.
19253	reductive pentose-phosphate cycle	P	The fixation of carbon dioxide (CO2) as glucose in the chloroplasts of C3 plants; uses ATP and NADPH formed in the light reactions of photosynthesis; carbon dioxide reacts with ribulose 1,5-bisphosphate (catalyzed by the function of ribulose-bisphosphate carboxylase) to yield two molecules of 3-phosphoglycerate; these are then phosphorylated by ATP to 1,3-bisphosphateglyceraldehyde which, in turn, is then reduced by NADPH to glyceraldehyde 3-phosphate. The glyceraldehyde 3-phosphate is converted to fructose 5-phosphate and ribulose 5-phosphate by aldolase and other enzymes; the ribulose 5-phosphate is phosphorylated by ATP to ribulose 1,5-bisphosphate.
19254	carnitine metabolic process, CoA-linked	P	The chemical reactions and pathways involving carnitine, where metabolism is linked to CoA.
19255	glucose 1-phosphate metabolic process	P	The chemical reactions and pathways involving glucose 1-phosphate, a monophosphorylated derivative of glucose with the phosphate group attached to C-1.
19256	acrylonitrile catabolic process	P	The chemical reactions and pathways resulting in the breakdown of acrylonitrile, a colorless, volatile liquid with a pungent odor. Acrylonitrile is used in the production of acrylic fibers, plastics, and synthetic rubbers.
19257	4-nitrotoluene metabolic process	P	The chemical reactions and pathways involving 4-nitrotoluene, 1-methyl-4-nitrobenzene. It is a light yellow liquid with a weak aromatic odor.
19258	4-nitrotoluene catabolic process	P	The chemical reactions and pathways resulting in the breakdown of 4-nitrotoluene, 1-methyl-4-nitrobenzene.
19260	1,2-dichloroethane catabolic process	P	The chemical reactions and pathways resulting in the breakdown of 1,2-dichloroethane, a major commodity chemical used, for example, in the manufacture of vinyl chloride.
19261	1,4-dichlorobenzene catabolic process	P	The chemical reactions and pathways resulting in the breakdown of 1,4-dichlorobenzene (p-dichlorobenzene or paramoth), a derivative of benzene with two chlorine atoms attached at opposite positions on the ring.
19262	N-acetylneuraminate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of N-acetylneuraminate, the anion of 5-(acetylamino)-3,5-dideoxy-D-glycero-D-galacto-non-3-ulosonic acid.
19263	adamantanone catabolic process	P	The chemical reactions and pathways resulting in the breakdown of adamantanone, tricyclo(3.3.1.13,7)decanone, a white crystalline solid used as an intermediate for microelectronics in the production of photoresists.
19264	glycine biosynthetic process from serine	P	The chemical reactions and pathways resulting in the formation of glycine from other compounds, including serine.
19265	glycine biosynthetic process, by transamination of glyoxylate	P	The chemical reactions and pathways resulting in the formation of glycine by the transamination of glyoxylate.
19266	asparagine biosynthetic process from oxaloacetate	P	The chemical reactions and pathways resulting in the formation of asparagine from other compounds, including oxaloacetate.
19267	asparagine biosynthetic process from cysteine	P	The chemical reactions and pathways resulting in the formation of asparagine from other compounds, including cysteine.
19270	aerobactin biosynthetic process	P	The chemical reactions and pathways resulting in the formation of aerobactin (C22H36N4O13), a hydroxamate iron transport compound. It is a conjugate of 6-(N-acetyl-N-hydroxylamine)-2-aminohexanoic acid and citric acid.
19271	aerobactin transport	P	The directed movement of the hydroxamate iron transport compound aerobactin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Aerobactin (C22H36N4O13) is a conjugate of 6-(N-acetyl-N-hydroxylamine)-2-aminohexanoic acid and citric acid.
19272	L-alanine biosynthetic process from pyruvate	P	The chemical reactions and pathways resulting in the formation of alanine from other compounds, including pyruvate.
19273	L-alanine biosynthetic process via ornithine	P	The chemical reactions and pathways resulting in the formation of L-alanine, via the intermediate ornithine.
19276	UDP-N-acetylgalactosamine metabolic process	P	The chemical reactions and pathways involving UDP-N-acetylgalactosamine, a substance composed of N-acetylgalactosamine, a common structural unit of oligosaccharides, in glycosidic linkage with uridine diphosphate.
19277	UDP-N-acetylgalactosamine biosynthetic process	P	The chemical reactions and pathways resulting in the formation of UDP-N-acetylgalactosamine, a substance composed of N-acetylgalactosamine, a common structural unit of oligosaccharides, in glycosidic linkage with uridine diphosphate.
19278	UDP-N-acetylgalactosamine catabolic process	P	The chemical reactions and pathways resulting in the breakdown of UDP-N-acetylgalactosamine, a substance composed of N-acetylgalactosamine, a common structural unit of oligosaccharides, in glycosidic linkage with uridine diphosphate.
19279	L-methionine biosynthetic process from L-homoserine via cystathionine	P	The chemical reactions and pathways resulting in the formation of L-methionine from other compounds, including L-homoserine, via the intermediate cystathionine.
19280	L-methionine biosynthetic process from homoserine via O-acetyl-L-homoserine and cystathionine	P	The chemical reactions and pathways resulting in the formation of methionine from other compounds, including homoserine, via the intermediates O-acetyl-L-homoserine and cystathionine.
19281	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine	P	The chemical reactions and pathways resulting in the formation of L-methionine from other compounds, including homoserine, via the intermediates O-succinyl-L-homoserine and cystathionine.
19283	L-methionine biosynthetic process from O-phospho-L-homoserine and cystathionine	P	The chemical reactions and pathways resulting in the formation of L-methionine from other compounds, including O-phospho-L-homoserine and cystathionine.
19284	L-methionine salvage from S-adenosylmethionine	P	The chemical reactions and pathways resulting in the formation of L-methionine from S-adenosylmethionine.
19285	glycine betaine biosynthetic process from choline	P	The chemical reactions and pathways resulting in the formation of betaine (N-trimethylglycine) from the oxidation of choline.
19286	glycine betaine biosynthetic process from glycine	P	The chemical reactions and pathways resulting in the formation of glycine betaine from other compounds, including glycine.
19287	isopentenyl diphosphate biosynthetic process, mevalonate pathway	P	The chemical reactions and pathways resulting in the formation of isopentenyl diphosphate, via the intermediate mevalonate. This pathway converts acetate, in the form of acetyl-CoA, to isopentenyl diphosphate (IPP), the fundamental unit in isoprenoid biosynthesis, through a series of mevalonate intermediates.
19288	isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway	P	The chemical reactions and pathways resulting in the formation of isopentenyl diphosphate by the mevalonate-independent pathway. Isopentenyl diphosphate (IPP) is the fundamental unit in isoprenoid biosynthesis and is biosynthesized from pyruvate and glyceraldehyde 3-phosphate via intermediates, including 1-deoxy-D-xylulose 5-phosphate.
19289	rhizobactin 1021 biosynthetic process	P	The chemical reactions and pathways resulting in the formation of rhizobactin 1021, (E)-4-((3-(acetylhydroxyamino)propyl)-amino)-2-hydroxy-(2-(2-(3-(hydroxy(1-oxo-2-decenyl)amino)propyl)amino)-2-oxoethyl)-4-oxobutanoic acid, a siderophore produced by Sinorhizobium meliloti.
19290	siderophore biosynthetic process	P	The chemical reactions and pathways resulting in the formation of siderophores, low molecular weight Fe(III)-chelating substances made by aerobic or facultatively anaerobic bacteria, especially when growing under iron deficient conditions. The complexes of Fe(3+)-siderophores have very high stability constants and are taken up by specific transport systems by microorganisms; the subsequent release of iron requires enzymatic action.
19292	tyrosine biosynthetic process from chorismate via 4-hydroxyphenylpyruvate	P	The chemical reactions and pathways resulting in the formation of tyrosine from other compounds, including chorismate, via the intermediate 4-hydroxyphenylpyruvate.
19293	tyrosine biosynthetic process, by oxidation of phenylalanine	P	The chemical reactions and pathways resulting in the formation of tyrosine by the oxidation of phenylalanine.
19294	keto-3-deoxy-D-manno-octulosonic acid biosynthetic process	P	The chemical reactions and pathways resulting in the formation of keto-3-deoxy-D-manno-octulosonic acid, an acidic sugar present in lipopolysaccharides of the outer membranes of some Gram-negative bacteria.
19295	coenzyme M biosynthetic process	P	The chemical reactions and pathways resulting in the formation of coenzyme M (2-thioethansulfonate), a coenzyme involved in the utilization of methane by methanogenic prokaryotes.
19296	coenzyme M metabolic process	P	The chemical reactions and pathways involving coenzyme M (2-thioethansulfonate), a coenzyme involved in the utilization of methane by methanogenic prokaryotes.
19297	coenzyme B metabolic process	P	The chemical reactions and pathways involving coenzyme B (7-mercaptoheptanoylthreonine phosphate), a coenzyme involved in the utilization of methane by methanogenic prokaryotes.
19298	coenzyme B biosynthetic process	P	The chemical reactions and pathways resulting in the formation of coenzyme B (7-mercaptoheptanoylthreonine phosphate), a coenzyme involved in the utilization of methane by methanogenic prokaryotes.
19299	rhamnose metabolic process	P	The chemical reactions and pathways involving rhamnose, the hexose 6-deoxy-L-mannose. Rhamnose occurs commonly as a compound of plant glycosides, in polysaccharides of gums and mucilages, and in bacterial polysaccharides. It is also a component of some plant cell wall polysaccharides and frequently acts as the sugar components of flavonoids.
19300	rhamnose biosynthetic process	P	The chemical reactions and pathways resulting in the formation of rhamnose, the hexose 6-deoxy-L-mannose.
19301	rhamnose catabolic process	P	The chemical reactions and pathways resulting in the breakdown of rhamnose, the hexose 6-deoxy-L-mannose.
19302	D-ribose biosynthetic process	P	The chemical reactions and pathways resulting in the formation of D-ribose, (ribo-pentose).
19303	D-ribose catabolic process	P	The chemical reactions and pathways resulting in the breakdown of D-ribose (ribo-pentose).
19304	anaerobic rhamnose catabolic process	P	The chemical reactions and pathways resulting in the breakdown of rhamnose, the hexose 6-deoxy-L-mannose, that occurs in the absence of oxygen.
19305	dTDP-rhamnose biosynthetic process	P	The chemical reactions and pathways resulting in the formation of dTDP-rhamnose, a substance composed of rhamnose in glycosidic linkage with deoxyribosylthymine diphosphate.
19306	GDP-D-rhamnose biosynthetic process	P	The chemical reactions and pathways resulting in the formation of GDP-D-rhamnose, a substance composed of rhamnose in glycosidic linkage with guanosine diphosphate.
19307	mannose biosynthetic process	P	The chemical reactions and pathways resulting in the formation of mannose, the aldohexose manno-hexose, the C-2 epimer of glucose.
19308	dTDP-mannose biosynthetic process	P	The chemical reactions and pathways resulting in the formation of dTDP-mannose, a substance composed of mannose in glycosidic linkage with deoxyribosylthymine diphosphate.
19309	mannose catabolic process	P	The chemical reactions and pathways resulting in the breakdown of mannose, the aldohexose manno-hexose, the C-2 epimer of glucose.
19310	inositol catabolic process	P	The chemical reactions and pathways resulting in the breakdown of inositol, 1,2,3,4,5,6-cyclohexanehexol, a growth factor for animals and microorganisms.
19311	sorbose metabolic process	P	The chemical reactions and pathways involving sorbose, the ketohexose xylo-2-hexulose. Sorbose is produced commercially by fermentation and is used as an intermediate in the manufacture of ascorbic acid.
19312	L-sorbose metabolic process	P	The chemical reactions and pathways involving sorbose, the L-enantiomer of the ketohexose xylo-2-hexulose. L-sorbose is formed by bacterial oxidation of sorbitol.
19313	allose metabolic process	P	The chemical reactions and pathways involving allose, allo-hexose, an aldohexose similar to glucose, differing only in the configuration of the hydroxyl group of C-3.
19314	D-allose metabolic process	P	The chemical reactions and pathways involving D-allose, the D-enantiomer of allo-hexose, an aldohexose similar to glucose.
19315	D-allose biosynthetic process	P	The chemical reactions and pathways resulting in the formation of D-allose, the D-enantiomer of allo-hexose, an aldohexose similar to glucose.
19316	D-allose catabolic process	P	The chemical reactions and pathways resulting in the breakdown of D-allose, the D-enantiomer of allo-hexose, an aldohexose similar to glucose.
19317	fucose catabolic process	P	The chemical reactions and pathways resulting in the breakdown of fucose (6-deoxygalactose).
19318	hexose metabolic process	P	The chemical reactions and pathways involving a hexose, any monosaccharide with a chain of six carbon atoms in the molecule.
19319	hexose biosynthetic process	P	The chemical reactions and pathways resulting in the formation of hexose, any monosaccharide with a chain of six carbon atoms in the molecule.
19320	hexose catabolic process	P	The chemical reactions and pathways resulting in the breakdown of hexose, any monosaccharide with a chain of six carbon atoms in the molecule.
19321	pentose metabolic process	P	The chemical reactions and pathways involving a pentose, any monosaccharide with a chain of five carbon atoms in the molecule.
19322	pentose biosynthetic process	P	The chemical reactions and pathways resulting in the formation of a pentose, any monosaccharide with a chain of five carbon atoms in the molecule.
19323	pentose catabolic process	P	The chemical reactions and pathways resulting in the breakdown of a pentose, any monosaccharide with a chain of five carbon atoms in the molecule.
19324	L-lyxose metabolic process	P	The chemical reactions and pathways involving L-lyxose, the L-enantiomer of aldopentose lyxo-pentose, the C-2 epimer of xylose.
19325	anaerobic fructose catabolic process	P	The chemical reactions and pathways resulting in the breakdown of fructose that occurs in the absence of oxygen.
19326	nitrotoluene metabolic process	P	The chemical reactions and pathways involving nitrotoluene, any methylbenzene molecule with NO2 group(s) attached.
19327	lead sulfide oxidation	P	The chemical reactions and pathways resulting in the conversion of lead sulfide to lead sulfate.
19328	anaerobic gallate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of gallate, the anion of gallic acid, in the absence of oxygen.
19329	ammonia oxidation	P	The chemical reactions and pathways by which ammonia or ammonium is converted to molecular nitrogen or another nitrogen compound, with accompanying loss of electrons.
19330	aldoxime metabolic process	P	The chemical reactions and pathways involving aldoximes, compounds derived by the reaction of an aldose with hydroxylamine, thus containing the aldoxime group -HC=NOH.
19331	anaerobic respiration, using ammonium as electron donor	P	The oxidation of ammonium (NH4) to nitrogen (N2) in the absence of oxygen, using nitrite (NO2) as the electron acceptor. It is suggested that hydroxylamine and ammonium are combined to yield hydrazine, which is subsequently oxidized to N2.
19332	aerobic respiration, using nitrite as electron donor	P	The oxidation of nitrite (NO2) to nitrate (NO3), using oxygen (O2) as the electron acceptor. Nitrite oxidation is the final step in nitrification, the oxidation of ammonia to nitrate, and nitrite oxidoreductase (NOR) is the key enzyme complex that catalyzes the conversion of nitrite to nitrate in nitrite oxidizing species.
19333	denitrification pathway	P	The reduction of nitrate to dinitrogen by four reactions; each intermediate is transformed to the next lower oxidation state; also part of cellular bioenergetics; the nitrogen compounds can serve as terminal acceptors for electron transport phosphorylation in place of oxygen.
19334	p-cymene catabolic process	P	The chemical reactions and pathways resulting in the breakdown of p-cymene, 1-methyl-4-isopropylbenzene, one of the alkyl-substituted aromatic hydrocarbons found in volatile oils from over 100 plants.
19335	3-methylquinoline catabolic process	P	The chemical reactions and pathways resulting in the breakdown of 3-methylquinoline, C10H9N, an aromatic compound composed of a benzene ring and a heterocyclic N-containing ring.
19336	phenol-containing compound catabolic process	P	The chemical reactions and pathways resulting in the breakdown of a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring.
19337	tetrachloroethylene catabolic process	P	The chemical reactions and pathways resulting in the breakdown of tetrachloroethylene, a derivative of ethene with the hydrogen atoms replaced by chlorines.
19338	pentachlorophenol catabolic process	P	The chemical reactions and pathways resulting in the breakdown of pentachlorophenol, a chlorinated insecticide and fungicide used primarily to protect timber from fungal rot and wood boring insects. Pentachlorophenol is significantly toxic to mammals, plants, and many microorganisms.
19339	parathion catabolic process	P	The chemical reactions and pathways resulting in the breakdown of parathion, a highly toxic organophosphate compound. Degradation of parathion by sunlight or liver enzymes can result in the formation of the active compound paraoxon which interferes with the nervous system through cholinesterase inhibition.
19340	dibenzofuran catabolic process	P	The chemical reactions and pathways resulting in the breakdown of dibenzofuran, a substance composed of two benzene rings linked by one ether bond and one carbon-carbon bond.
19341	dibenzo-p-dioxin catabolic process	P	The chemical reactions and pathways resulting in the breakdown of dibenzo-p-dioxin, a substance composed of two benzene rings linked by two ether bonds.
19342	trypanothione biosynthetic process	P	The chemical reactions and pathways resulting in the formation of trypanothione (N1,N6,-bis(glutathionyl)spermidine) in two steps from glutathione and spermidine via an N1- or N8-glutathionylspermidine intermediate. Trypanothione appears to be an essential redox intermediate in intracellular thiol redox regulation. It also plays a role in protecting against oxidative stress.
19343	cysteine biosynthetic process via cystathionine	P	The chemical reactions and pathways resulting in the formation of cysteine, via the intermediate cystathionine.
19344	cysteine biosynthetic process	P	The chemical reactions and pathways resulting in the formation of cysteine, 2-amino-3-mercaptopropanoic acid.
19345	cysteine biosynthetic process via S-sulfo-L-cysteine	P	The chemical reactions and pathways resulting in the formation of cysteine, via the intermediate S-sulfo-L-cysteine.
19346	transsulfuration	P	The interconversion of homocysteine and cysteine via cystathionine. In contrast with enteric bacteria and mammals, Saccharomyces cerevisiae has two transsulfuration pathways employing two separate sets of enzymes.
19347	GDP-alpha-D-mannosylchitobiosyldiphosphodolichol biosynthetic process	P	The chemical reactions and pathways resulting in the formation of GDP-alpha-D-mannosylchitobiosyldiphosphodolichol, a substance composed of mannosylchitobiosyldiphosphodolichol in glycosidic linkage with guanosine diphosphate.
19348	dolichol metabolic process	P	The chemical reactions and pathways involving dolichols, any 2,3-dihydropolyprenol derived from four or more linked isoprene units.
19349	ribitol metabolic process	P	The chemical reactions and pathways involving ribitol, a pentitol derived formally by reduction of the -CHO group of either D- or L-ribose. It occurs free in some plants and is a component of riboflavin.
19350	teichoic acid biosynthetic process	P	The chemical reactions and pathways resulting in the formation of teichoic acid, any polymer occurring in the cell wall, membrane or capsule of Gram-positive bacteria and containing chains of glycerol phosphate or ribitol phosphate residues.
19351	dethiobiotin biosynthetic process	P	The chemical reactions and pathways resulting in the formation of dethiobiotin, a derivative of biotin in which the sulfur atom has been replaced by two hydrogen atoms.
19352	protoporphyrinogen IX biosynthetic process from glycine	P	The chemical reactions and pathways resulting in the formation of protoporphyrinogen IX from other compounds, including glycine.
19353	protoporphyrinogen IX biosynthetic process from glutamate	P	The chemical reactions and pathways resulting in the formation of protoporphyrinogen IX from other compounds, including glutamate.
19354	siroheme biosynthetic process	P	The chemical reactions and pathways resulting in the formation of siroheme, a tetrahydroporphyrin with adjacent, reduced pyrrole rings.
19355	nicotinamide nucleotide biosynthetic process from aspartate	P	The chemical reactions and pathways resulting in the formation of nicotinamide nucleotide from other compounds, including aspartate.
19356	nicotinate nucleotide biosynthetic process from tryptophan	P	The chemical reactions and pathways resulting in the formation of nicotinate nucleotide from other compounds, including tryptophan.
19357	nicotinate nucleotide biosynthetic process	P	The chemical reactions and pathways resulting in the formation of nicotinamide nucleotides, any nucleotide that contains combined nicotinate (pyridine 3-carboxylic acid).
19358	nicotinate nucleotide salvage	P	The generation of nicotinate nucleotide without de novo synthesis.
19359	nicotinamide nucleotide biosynthetic process	P	The chemical reactions and pathways resulting in the formation of nicotinamide nucleotides, any nucleotide that contains combined nicotinamide.
19360	nicotinamide nucleotide biosynthetic process from niacinamide	P	The chemical reactions and pathways resulting in the formation of nicotinamide nucleotide from other compounds, including niacinamide.
19361	2'-(5''-triphosphoribosyl)-3'-dephospho-CoA biosynthetic process	P	The chemical reactions and pathways resulting in the formation of 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA, a derivative of coenzyme A.
19362	pyridine nucleotide metabolic process	P	The chemical reactions and pathways involving a pyridine nucleotide, a nucleotide characterized by a pyridine derivative as a nitrogen base.
19363	pyridine nucleotide biosynthetic process	P	The chemical reactions and pathways resulting in the formation of a pyridine nucleotide, a nucleotide characterized by a pyridine derivative as a nitrogen base.
19364	pyridine nucleotide catabolic process	P	The chemical reactions and pathways resulting in the breakdown of a pyridine nucleotide, a nucleotide characterized by a pyridine derivative as a nitrogen base.
19365	pyridine nucleotide salvage	P	Any process that generates a pyridine nucleotide, a nucleotide characterized by a pyridine derivative as a nitrogen base, from derivatives of them without de novo synthesis.
19367	fatty acid elongation, saturated fatty acid	P	Elongation of a saturated fatty acid chain.
19368	fatty acid elongation, unsaturated fatty acid	P	Elongation of a fatty acid chain into which one or more C-C double bonds have been introduced.
19369	arachidonic acid metabolic process	P	The chemical reactions and pathways involving arachidonic acid, a straight chain fatty acid with 20 carbon atoms and four double bonds per molecule. Arachidonic acid is the all-Z-(5,8,11,14)-isomer.
19370	leukotriene biosynthetic process	P	The chemical reactions and pathways resulting in the formation of leukotriene, a pharmacologically active substance derived from a polyunsaturated fatty acid, such as arachidonic acid.
19371	cyclooxygenase pathway	P	The chemical reactions and pathways by which prostaglandins are formed from arachidonic acid, and in which prostaglandin-endoperoxide synthase (cyclooxygenase) catalyzes the committed step in the conversion of arachidonic acid to the prostaglandin-endoperoxides PGG2 and PGH2.
19372	lipoxygenase pathway	P	The chemical reactions and pathways by which an unsaturated fatty acid (such as arachidonic acid or linolenic acid) is converted to other compounds, and in which the first step is hydroperoxide formation catalyzed by lipoxygenase.
19373	epoxygenase P450 pathway	P	The chemical reactions and pathways by which arachidonic acid is converted to other compounds including epoxyeicosatrienoic acids and dihydroxyeicosatrienoic acids.
19374	galactolipid metabolic process	P	The chemical reactions and pathways involving galactolipids, any glycolipid containing one of more residues of galactose and/or N-acetylgalactosamine.
19375	galactolipid biosynthetic process	P	The chemical reactions and pathways resulting in the formation of galactolipids, any glycolipid containing one of more residues of galactose and/or N-acetylgalactosamine.
19376	galactolipid catabolic process	P	The chemical reactions and pathways resulting in the breakdown of galactolipids, any glycolipid containing one of more residues of galactose and/or N-acetylgalactosamine.
19377	glycolipid catabolic process	P	The chemical reactions and pathways resulting in the breakdown of glycolipid, a class of 1,2-di-O-acylglycerols joined at oxygen 3 by a glycosidic linkage to a carbohydrate part (usually a mono-, di- or tri-saccharide).
19379	sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin)	P	The pathway by which inorganic sulfate is processed and incorporated into sulfated compounds, where the phosphoadenylyl sulfate reduction step is catalyzed by the enzyme phosphoadenylyl-sulfate reductase (thioredoxin) (EC:1.8.4.8).
19380	3-phenylpropionate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of 3-phenylpropionate, the anion of phenylpropanoic acid.
19381	atrazine catabolic process	P	The chemical reactions and pathways resulting in the breakdown of atrazine, a triazine ring-containing herbicide.
19382	carbon tetrachloride catabolic process	P	The chemical reactions and pathways resulting in the breakdown of carbon tetrachloride, a toxic, carcinogenic compound which is used as a general solvent in industrial degreasing operations. It is also used as grain fumigant and a chemical intermediate in the production of refrigerants.
19383	(+)-camphor catabolic process	P	The chemical reactions and pathways resulting in the breakdown of (+)-camphor, a bicyclic monoterpene ketone.
19384	caprolactam catabolic process	P	The chemical reactions and pathways resulting in the breakdown of caprolactam, hexahydro-2h-azepin-2-one, a cyclic amide of caproic acid.
19385	methanogenesis, from acetate	P	The formation of methane, a colorless, odorless, flammable gas with the formula CH4, from other components, including acetate.
19386	methanogenesis, from carbon dioxide	P	The chemical reactions and pathways resulting in the formation of methane, a colorless, odorless, flammable gas with the formula CH4, from other compounds, including carbon dioxide (CO2).
19387	methanogenesis, from methanol	P	The formation of methane, a colorless, odorless, flammable gas with the formula CH4, from other components, including methanol.
19388	galactose catabolic process	P	The chemical reactions and pathways resulting in the breakdown of galactose, the aldohexose galacto-hexose.
19389	glucuronoside metabolic process	P	The chemical reactions and pathways involving glucuronosides, any compound formed by combination in glycosidic linkage of a hydroxy compound with the anomeric carbon atom of a glucuronate.
19390	glucuronoside biosynthetic process	P	The chemical reactions and pathways resulting in the formation of glucuronosides, compound composed of a hydroxy compound linked to a glucuronate residue.
19391	glucuronoside catabolic process	P	The chemical reactions and pathways resulting in the breakdown of glucuronosides, compound composed of a hydroxy compound linked to a glucuronate residue.
19392	glucarate metabolic process	P	The chemical reactions and pathways involving glucarate, the dianion of glucaric acid, an aldaric acid derived from either glucose or gulose. There are two enantiomers L- and D-glucarate.
19393	glucarate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of glucarate, the anion of glucaric acid.
19394	glucarate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of glucarate, the anion of glucaric acid.
19395	fatty acid oxidation	P	The removal of one or more electrons from a fatty acid, with or without the concomitant removal of a proton or protons, by reaction with an electron-accepting substance, by addition of oxygen or by removal of hydrogen.
19396	gallate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of gallate, the anion of gallic acid (3,4,5-trihydroxybenzoic acid).
19397	gallate catabolic process via 2-pyrone-4,6-dicarboxylate	P	The chemical reactions and pathways resulting in the breakdown of gallate, the anion of gallic acid, via the intermediate 2-pyrone-4,6-dicarboxylate.
19398	gallate catabolic process via gallate dioxygenase activity	P	The chemical reactions and pathways resulting in the breakdown of gallate, the anion of gallic acid, where the first step is the conversion of gallate to (1E)-4-oxobut-1-ene-1,2,4-tricarboxylate catalyzed by gallate dioxygenase.
19399	cyclohexanol oxidation	P	The cyclohexanol metabolic process in which cyclohexanol is converted to adipate.
19400	alditol metabolic process	P	The chemical reactions and pathways involving alditols, any polyhydric alcohol derived from the acyclic form of a monosaccharide by reduction of its aldehyde or keto group to an alcoholic group.
19401	alditol biosynthetic process	P	The chemical reactions and pathways resulting in the formation of alditols, any polyhydric alcohol derived from the acyclic form of a monosaccharide by reduction of its aldehyde or keto group to an alcoholic group.
19402	galactitol metabolic process	P	The chemical reactions and pathways involving galactitol, the hexitol derived by the reduction of the aldehyde group of either D- or L-galactose.
19403	galactitol biosynthetic process	P	The chemical reactions and pathways resulting in the formation of galactitol, the hexitol derived by the reduction of the aldehyde group of either D- or L-galactose.
19404	galactitol catabolic process	P	The chemical reactions and pathways resulting in the breakdown of galactitol, the hexitol derived by the reduction of the aldehyde group of either D- or L-galactose.
19405	alditol catabolic process	P	The chemical reactions and pathways resulting in the breakdown of alditols, any polyhydric alcohol derived from the acyclic form of a monosaccharide by reduction of its aldehyde or keto group to an alcoholic group.
19406	hexitol biosynthetic process	P	The chemical reactions and pathways resulting in the formation of hexitols, any alditol with a chain of six carbon atoms in the molecule.
19407	hexitol catabolic process	P	The chemical reactions and pathways resulting in the breakdown of hexitols, any alditol with a chain of six carbon atoms in the molecule.
19408	dolichol biosynthetic process	P	The chemical reactions and pathways resulting in the formation of dolichols, any 2,3-dihydropolyprenol derived from four or more linked isoprene units.
19409	aerobic respiration, using ammonia as electron donor	P	The metabolic process in which ammonia (NH3) is oxidized to nitrite (NO2) in the presence of oxygen; enzymatic reactions convert ammonia to hydrazine, and hydrazine to nitrite.
19410	aerobic respiration, using carbon monoxide as electron donor	P	The metabolic process in which carbon monoxide (CO) is oxidized to carbon dioxide (CO2) to generate energy. Conservation of energy in this process likely uses sodium ion gradients for ATP synthesis and is coupled to quantitative sulfide methylation.
19411	aerobic respiration, using ferrous ions as electron donor	P	The metabolic process in which ferrous ions (Fe2+) are oxidized to ferric ions (Fe3+) to generate energy, coupled to the reduction of carbon dioxide.
19412	aerobic respiration, using hydrogen as electron donor	P	The oxidation of hydrogen (H2) to water (H2O), using oxygen (O2) as the electron acceptor. A hydrogenase enzyme binds H2 and the hydrogen atoms are passed through an electron transfer chain to O2 to form water.
19413	acetate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of acetate, the anion of acetic acid.
19414	aerobic respiration, using sulfur or sulfate as electron donor	P	An aerobic respiration process in which a sulfur-containing molecule (hydrogen sulfide, sulfur, sulfite, thiosulfate, and various polythionates) is oxidized.
19415	acetate biosynthetic process from carbon monoxide	P	The chemical reactions and pathways resulting in the formation of acetate from other compounds, including carbon monoxide.
19416	polythionate oxidation	P	The chemical reactions and pathways resulting in the conversion of thiosulfate to tetrathionate, using cytochrome c as an electron acceptor.
19417	sulfur oxidation	P	The chemical reactions and pathways resulting the addition of oxygen to elemental sulfur.
19418	sulfide oxidation	P	The chemical reactions and pathways resulting in the conversion of sulfide to elemental sulfur in a higher oxidation state, or to sulfite or sulfate.
19419	sulfate reduction	P	The chemical reactions and pathways resulting in the reduction of sulfate to another sulfur-containing ion or compound such as hydrogen sulfide, adenosine-phosphosulfate (APS) or thiosulfate.
19420	dissimilatory sulfate reduction	P	The reduction of sulfate to hydrogen sulfide, which acts as a terminal electron acceptor. Sulfate is activated to adenosine-phosphosulfate (APS) which is then reduced to sulfite, which is in turn reduced to hydrogen sulfide.
19422	disproportionation of elemental sulfur	P	The process in which sulfur compounds with an intermediate oxidation state serve as both electron donors and electron acceptors in an energy-generating redox process. The reaction takes place anaerobically, in light and in the absence of CO2.
19423	sulfur oxidation, ferric ion-dependent	P	A sulfur oxidation process that proceeds via the reaction catalyzed by sulfur:ferric ion oxidoreductase, and requires the presence of ferric ion (Fe3+).
19424	sulfide oxidation, using siroheme sulfite reductase	P	A sulfide oxidation process that proceeds via the reaction catalyzed by siroheme sulfite reductase.
19426	bisulfite reduction	P	The chemical reactions and pathways resulting in the reduction of sulfate to thiosulfate via bisulfite.
19427	acetyl-CoA biosynthetic process from acetate	P	The chemical reactions and pathways resulting in the formation of acetyl-CoA from acetate, either directly or via acetylphosphate.
19428	allantoin biosynthetic process	P	The chemical reactions and pathways resulting in the formation of allantoin, (2,5-dioxo-4-imidazolidinyl)urea.
19429	fluorene catabolic process	P	The chemical reactions and pathways resulting in the breakdown of fluorene, a tricyclic polycyclic aromatic hydrocarbon containing a five-membered ring. It is a major component of fossil fuels and their derivatives and is also a by-product of coal-conversion and energy-related industries. It is commonly found in vehicle exhaust emissions, crude oils, motor oils, coal and oil combustion products, waste incineration, and industrial effluents.
19430	removal of superoxide radicals	P	Any process, acting at the cellular level, involved in removing superoxide radicals (O2-) from a cell or organism, e.g. by conversion to dioxygen (O2) and hydrogen peroxide (H2O2).
19431	acetyl-CoA biosynthetic process from ethanol	P	The chemical reactions and pathways resulting in the formation of acetyl-CoA from ethanol via acetaldehyde.
19432	triglyceride biosynthetic process	P	The chemical reactions and pathways resulting in the formation of a triglyceride, any triester of glycerol.
19433	triglyceride catabolic process	P	The chemical reactions and pathways resulting in the breakdown of a triglyceride, any triester of glycerol.
19434	sophorosyloxydocosanoate metabolic process	P	The chemical reactions and pathways involving sophorosyloxydocosanoate, 13-sophorosyloxydocosanoate 6',6''-diacetate, an aromatic hydrocarbon.
19435	sophorosyloxydocosanoate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of sophorosyloxydocosanoate, 13-sophorosyloxydocosanoate 6',6''-diacetate.
19436	sophorosyloxydocosanoate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of sophorosyloxydocosanoate, 13-sophorosyloxydocosanoate 6',6''-diacetate.
19438	aromatic compound biosynthetic process	P	The chemical reactions and pathways resulting in the formation of aromatic compounds, any substance containing an aromatic carbon ring.
19439	aromatic compound catabolic process	P	The chemical reactions and pathways resulting in the breakdown of aromatic compounds, any substance containing an aromatic carbon ring.
19440	tryptophan catabolic process to indole-3-acetate	P	The chemical reactions and pathways resulting in the breakdown of tryptophan into other compounds, including indole-3-acetate.
19441	tryptophan catabolic process to kynurenine	P	The chemical reactions and pathways resulting in the breakdown of tryptophan into other compounds, including kynurenine.
19442	tryptophan catabolic process to acetyl-CoA	P	The chemical reactions and pathways resulting in the breakdown of tryptophan into other compounds, including acetyl-CoA.
19444	tryptophan catabolic process to catechol	P	The chemical reactions and pathways resulting in the breakdown of tryptophan into other compounds, including catechol.
19445	tyrosine catabolic process to fumarate	P	The chemical reactions and pathways resulting in the breakdown of tyrosine into other compounds, including fumarate.
19446	tyrosine catabolic process to phosphoenolpyruvate	P	The chemical reactions and pathways resulting in the breakdown of tyrosine into other compounds, including phosphoenolpyruvate.
19447	D-cysteine catabolic process	P	The chemical reactions and pathways resulting in the breakdown of D-cysteine, (S)-2-amino-3-mercaptopropanoic acid, which occurs naturally in firefly luciferin.
19448	L-cysteine catabolic process	P	The chemical reactions and pathways resulting in the breakdown of L-cysteine, the L-enantiomer of 2-amino-3-mercaptopropanoic acid, i.e. (2R)-2-amino-3-mercaptopropanoic acid.
19449	L-cysteine catabolic process to hypotaurine	P	The chemical reactions and pathways resulting in the breakdown of L-cysteine into other compounds, including hypotaurine.
19450	L-cysteine catabolic process to pyruvate	P	The chemical reactions and pathways resulting in the breakdown of L-cysteine into other compounds, including pyruvate.
19451	L-cysteine catabolic process to pyruvate, using cysteine dioxygenase	P	The chemical reactions and pathways resulting in the breakdown into pyruvate of L-cystine, catalyzed by the enzyme cysteine dioxygenase (EC:1.13.11.20).
19452	L-cysteine catabolic process to taurine	P	The chemical reactions and pathways resulting in the breakdown of L-cysteine into other compounds, including taurine.
19453	L-cysteine catabolic process via cystine	P	The chemical reactions and pathways resulting in the breakdown of L-cysteine, via the intermediate cystine.
19454	L-cysteine catabolic process via cystine, using glutathione-cystine transhydrogenase	P	The chemical reactions and pathways resulting in the breakdown, via the compound cystine, of L-cysteine, catalyzed by the enzyme glutathione-cystine transhydrogenase (EC:1.8.4.4).
19455	L-cysteine catabolic process via cystine, using cystine reductase	P	The chemical reactions and pathways resulting in the breakdown, via the compound cystine, of L-cysteine, catalyzed by the enzyme cystine reductase (EC:1.8.1.6).
19456	L-cysteine catabolic process via cystine, using cysteine transaminase	P	The chemical reactions and pathways resulting in the breakdown, via the compound cystine, of L-cysteine, catalyzed by the enzyme cysteine transaminase (EC:2.6.1.3).
19457	methionine catabolic process to succinyl-CoA	P	The chemical reactions and pathways resulting in the breakdown of methionine into other compounds, including succinyl-CoA.
19458	methionine catabolic process via 2-oxobutanoate	P	The chemical reactions and pathways resulting in the breakdown of methionine, via the intermediate 2-oxobutanoate.
19460	glutamine catabolic process to fumarate	P	The chemical reactions and pathways resulting in the breakdown of glutamine into other compounds, including fumarate.
19461	glutamine catabolic process to fumarate, using glutamate synthase (NADPH)	P	The chemical reactions and pathways resulting in the breakdown of glutamine into fumarate, beginning with the conversion of glutamine to glutamate catalyzed by the enzyme glutamate synthase (NADPH) (EC:1.4.1.13).
19462	glutamine catabolic process to fumarate, using glutaminase	P	The chemical reactions and pathways resulting in the breakdown of glutamine into fumarate, beginning with conversion of glutamine into glutamate catalyzed by the enzyme glutaminase (EC:3.5.1.2).
19463	glycine catabolic process to creatine	P	The chemical reactions and pathways resulting in the breakdown of glycine into other compounds, including creatine.
19464	glycine decarboxylation via glycine cleavage system	P	The chemical reactions and pathways resulting in the breakdown of glycine by oxidative cleavage to carbon dioxide, ammonia, and a methylene group, mediated by enzymes of the glycine cleavage complex.
19465	aspartate transamidation	P	The exchange of the amino group of aspartate, the anion derived from aspartic acid, for another amino group.
19466	ornithine catabolic process via proline	P	The chemical reactions and pathways resulting in the breakdown of ornithine, via the intermediate proline.
19467	ornithine catabolic process, by decarboxylation	P	The chemical reactions and pathways resulting in the breakdown of ornithine by decarboxylation.
19468	nopaline catabolic process	P	The chemical reactions and pathways resulting in the breakdown of nopaline (N-(I-carboxy-4-guanidinobutyl)glutamic acid), a rare amino-acid derivative.
19469	octopine catabolic process	P	The chemical reactions and pathways resulting in the breakdown of octopine (N-(1-carboxy-4-guanidinobutyl)-L-alanine), an amino acid derived opine.
19470	4-hydroxyproline catabolic process	P	The chemical reactions and pathways resulting in the breakdown of 4-hydroxyproline, C5H9NO3, a derivative of the amino acid proline.
19471	4-hydroxyproline metabolic process	P	The chemical reactions and pathways involving 4-hydroxyproline, C5H9NO3, a derivative of the amino acid proline. The presence of hydroxyproline is essential to produce stable triple helical tropocollagen, hence the problems caused by ascorbate deficiency in scurvy. This unusual amino acid is also present in considerable amounts in the major glycoprotein of primary plant cell walls.
19472	4-hydroxyproline biosynthetic process	P	The chemical reactions and pathways resulting in the formation of 4-hydroxyproline, C5H9NO3, a derivative of the amino acid proline.
19473	L-lysine catabolic process to glutarate, by acetylation	P	The chemical reactions and pathways resulting in the breakdown of L-lysine into other compounds, including glutarate, by acetylation.
19474	L-lysine catabolic process to acetyl-CoA	P	The chemical reactions and pathways resulting in the breakdown of L-lysine into other compounds, including acetyl-CoA.
19475	L-lysine catabolic process to acetate	P	The chemical reactions and pathways resulting in the breakdown of L-lysine into other compounds, including acetate.
19476	D-lysine catabolic process	P	The chemical reactions and pathways resulting in the breakdown of D-lysine, the D-enantiomer of lysine; i.e. (2R)-2,6-diaminohexanoic acid.
19477	L-lysine catabolic process	P	The chemical reactions and pathways resulting in the breakdown of L-lysine, the L-enantiomer of (S)-2,6-diaminohexanoic acid.
19478	D-amino acid catabolic process	P	The chemical reactions and pathways resulting in the breakdown of D-amino acids, the D-enantiomers of amino acids.
19479	L-alanine oxidation to D-lactate and ammonia	P	The chemical reactions and pathways resulting in the breakdown of L-alanine to D-lactate and ammonia.
19480	L-alanine oxidation to pyruvate via D-alanine	P	The chemical reactions and pathways resulting in the breakdown of L-alanine to pyruvate, with D-alanine as an intermediate.
19481	L-alanine catabolic process, by transamination	P	The chemical reactions and pathways resulting in the breakdown of L-alanine by transamination.
19482	beta-alanine metabolic process	P	The chemical reactions and pathways involving beta-alanine (3-aminopropanoic acid), an achiral amino acid and an isomer of alanine. It occurs free (e.g. in brain) and in combination (e.g. in pantothenate) but it is not a constituent of proteins.
19483	beta-alanine biosynthetic process	P	The chemical reactions and pathways resulting in the formation of beta-alanine (3-aminopropanoic acid), an achiral amino acid and an isomer of alanine. It occurs free (e.g. in brain) and in combination (e.g. in pantothenate) but it is not a constituent of proteins.
19484	beta-alanine catabolic process	P	The chemical reactions and pathways resulting in the breakdown of beta-alanine (3-aminopropanoic acid), an achiral amino acid and an isomer of alanine. It occurs free (e.g. in brain) and in combination (e.g. in pantothenate) but it is not a constituent of proteins.
19485	beta-alanine catabolic process to L-alanine	P	The chemical reactions and pathways resulting in the breakdown of beta-alanine into other compounds, including L-alanine.
19486	beta-alanine catabolic process to mevalonate semialdehyde, by transamination	P	The chemical reactions and pathways resulting in the breakdown of beta-alanine into other compounds, including mevalonate semialdehyde, by transamination.
19487	anaerobic acetylene catabolic process	P	The chemical reactions and pathways involving acetylene, a colorless, volatile, explosive gas, that occur in the absence of oxygen.
19488	ribitol catabolic process to xylulose 5-phosphate	P	The chemical reactions and pathways resulting in the breakdown of ribitol to form xylulose 5-phosphate. Ribitol is initially converted to D-ribulose, which is phosphorylated to form ribulose 5-phosphate, which is then converted into xylulose 5-phosphate.
19489	methylgallate metabolic process	P	The chemical reactions and pathways involving methylgallate, trihydroxymethylbenzoate, the anion of methylgallic acid.
19490	2-aminobenzenesulfonate desulfonation	P	The removal of the sulfonate group from 2-aminobenzenesulfonate, an aromatic sulfonate used in organic synthesis and in the manufacture of various dyes and medicines.
19491	ectoine biosynthetic process	P	The chemical reactions and pathways resulting in the formation of ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidinecarboxylic acid), a tetrahydropyrimidine commonly synthesized by halophilic bacteria.
19492	proline salvage	P	Any process which produces the amino acid proline from derivatives of it, without de novo synthesis.
19493	arginine catabolic process to proline	P	The chemical reactions and pathways resulting in the breakdown of arginine into other compounds, including proline.
19495	proline catabolic process to 2-oxoglutarate	P	The chemical reactions and pathways resulting in the breakdown of proline into other compounds, including 2-oxoglutarate.
19496	serine-isocitrate lyase pathway	P	A one-carbon metabolic process in which acetyl-CoA is produced from formaldehyde and carbon dioxide.
19497	hexachlorocyclohexane metabolic process	P	The chemical reactions and pathways involving hexachlorocyclohexane, a cyclohexane derivative with 6 chlorine atoms attached to the hexane ring. Hexachlorocyclohexane consists of a mixture of 8 different isomers and was used a commercial insecticide. It is persistent in the environment, causing serious soil pollution.
19498	n-octane oxidation	P	The chemical reactions and pathways resulting in the conversion of n-octane to octanoyl-CoA.
19499	cyanide metabolic process	P	The chemical reactions and pathways involving cyanide, NC-, the anion of hydrocyanic acid. Cyanide is a potent inhibitor of respiration, reacting with the ferric form of cytochrome aa3 and thus blocking the electron transport chain.
19500	cyanide catabolic process	P	The chemical reactions and pathways resulting in the breakdown of cyanide, NC-, the anion of hydrocyanic acid. Cyanide is a potent inhibitor of respiration.
19501	arsonoacetate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of arsonoacetate, a synthetic, organic compound containing a single arsenic atom.
19502	stachydrine metabolic process	P	The chemical reactions and pathways involving stachydrine, N-methylproline methylbetaine, the betaine derivative of L-proline found in alfalfa, chrysanthemum, and citrus plants.
19503	stachydrine biosynthetic process	P	The chemical reactions and pathways resulting in the formation of stachydrine, N-methylproline methylbetaine, the betaine derivative of L-proline.
19504	stachydrine catabolic process	P	The chemical reactions and pathways resulting in the breakdown of stachydrine, N-methylproline methylbetaine, the betaine derivative of L-proline.
19505	resorcinol metabolic process	P	The chemical reactions and pathways involving resorcinol (C6H4(OH)2), a benzene derivative with many applications, including dyes, explosives, resins and as an antiseptic.
19506	phenylmercury acetate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of phenylmercury acetate, an organomercurial compound composed of a mercury atom attached to a benzene ring and an acetate group.
19507	pyridine metabolic process	P	The chemical reactions and pathways involving pyridine, a nitrogenous base (C5H5N) obtained from the distillation of bone oil or coal tar, and by the decomposition of certain alkaloids, as a colorless liquid with a peculiar pungent odor.
19508	2,5-dihydroxypyridine catabolic process to fumarate	P	The chemical reactions and pathways resulting in the breakdown of 2,5-dihydroxypyridine to form fumarate. 2,5-dihydroxypyridine is dioxygenated to give maleamate and formate; the maleamate from this reaction is then converted to maleate, which is then isomerized to fumurate.
19509	L-methionine salvage from methylthioadenosine	P	The generation of L-methionine (2-amino-4-(methylthio)butanoic acid) from methylthioadenosine.
19510	S-adenosylhomocysteine catabolic process	P	The chemical reactions and pathways resulting in the breakdown of S-adenosylhomocysteine, forming homocysteine and then methionine.
19511	peptidyl-proline hydroxylation	P	The hydroxylation of peptidyl-proline to form peptidyl-hydroxyproline.
19512	lactose catabolic process via tagatose-6-phosphate	P	The chemical reactions and pathways resulting in the breakdown of lactose, via the intermediate tagatose-6-phosphate.
19513	lactose catabolic process, using glucoside 3-dehydrogenase	P	The chemical reactions and pathways resulting in the breakdown of lactose, catalyzed by the enzyme glucoside 3-dehydrogenase (EC:1.1.99.13).
19515	lactose catabolic process via UDP-galactose	P	The chemical reactions and pathways resulting in the breakdown of lactose, via the intermediate UDP-galactose.
19516	lactate oxidation	P	The chemical reactions and pathways resulting in the conversion of lactate to other compounds, such as pyruvate, with concomitant loss of electrons.
19517	L-threonine catabolic process to D-lactate	P	The chemical reactions and pathways resulting in the breakdown of L- threonine (the L-enantiomer of 2-amino-3-hydroxybutyric acid) to form the compound methylglyoxal, which is subsequently converted to D-lactate.
19518	L-threonine catabolic process to glycine	P	The chemical reactions and pathways resulting in the breakdown of L-threonine (the L-enantiomer of 2-amino-3-hydroxybutyric acid) to form to form 2-amino-3-oxobutanoate, which is subsequently converted to glycine.
19519	pentitol metabolic process	P	The chemical reactions and pathways involving pentitols, any alditol with a chain of five carbon atoms in the molecule.
19520	aldonic acid metabolic process	P	The chemical reactions and pathways involving aldonic acid, a monocarboxylic acid with a chain of three or more carbon atoms, derived from an aldose by oxidation of the aldehydic group.
19521	D-gluconate metabolic process	P	The chemical reactions and pathways involving D-gluconate, the anion of D-gluconic acid, the aldonic acid derived from glucose.
19522	ketogluconate metabolic process	P	The chemical reactions and pathways involving ketogluconate, the anion of ketogluconic acid, an aldonic acid derived from glucose containing a ketonic carbonyl group.
19523	L-idonate metabolic process	P	The chemical reactions and pathways involving L-idonate, the anion of idonic acid, an aldonic acid derived from L-idose, an aldohexose which is epimeric with D-glucose.
19524	keto-D-gluconate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of keto-D-gluconate, the anion of keto-D-gluconic acid, an aldonic acid derived from glucose.
19525	keto-D-gluconate metabolic process	P	The chemical reactions and pathways involving keto-D-gluconate, the anion of keto-D-gluconic acid, an aldonic acid derived from glucose.
19526	pentitol biosynthetic process	P	The chemical reactions and pathways resulting in the formation of pentitols, any alditol with a chain of five carbon atoms in the molecule.
19527	pentitol catabolic process	P	The chemical reactions and pathways resulting in the breakdown of pentitols, any alditol with a chain of five carbon atoms in the molecule.
19528	D-arabitol catabolic process to xylulose 5-phosphate	P	The chemical reactions and pathways resulting in the breakdown of D-arabitol to form xylulose 5-phosphate. D-arabitol is converted into D-xylulose, which is then phosphorylated to form D-xylulose-5-phosphate.
19529	taurine catabolic process	P	The chemical reactions and pathways resulting in the breakdown of taurine (2-aminoethanesulfonic acid), a sulphur-containing amino acid derivative important in the metabolism of fats.
19530	taurine metabolic process	P	The chemical reactions and pathways involving taurine (2-aminoethanesulfonic acid), a sulphur-containing amino acid derivative important in the metabolism of fats.
19531	oxalate transmembrane transporter activity	F	Enables the transfer of oxalate from one side of the membrane to the other. Oxalate, or ethanedioic acid, occurs in many plants and is highly toxic to animals.
19532	oxalate transport	P	The directed movement of oxalate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Oxalate, or ethanedioic acid, occurs in many plants and is highly toxic to animals.
19533	cellobiose transport	P	The directed movement of cellobiose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Cellobiose, or 4-O-beta-D-glucopyranosyl-D-glucose, is a disaccharide that represents the basic repeating unit of cellulose.
19534	toxin transporter activity	F	Enables the directed movement of a toxin into, out of or within a cell, or between cells. A toxin is a poisonous compound (typically a protein) that is produced by cells or organisms and that can cause disease when introduced into the body or tissues of an organism.
19535	ferric-vibriobactin transmembrane transporter activity	F	Enables the transfer of ferric-vibriobactin ions from one side of a membrane to the other.
19536	vibriobactin metabolic process	P	The chemical reactions and pathways involving vibriobactin, the major siderophore produced by Vibrio cholerae.
19537	vibriobactin biosynthetic process	P	The chemical reactions and pathways resulting in the formation of vibriobactin, the major siderophore produced by Vibrio cholerae.
19538	protein metabolic process	P	The chemical reactions and pathways involving a specific protein, rather than of proteins in general. Includes protein modification.
19539	siderophore biosynthetic process from hydroxamic acid	P	The chemical reactions and pathways resulting in the formation of a siderophore from other compounds, including hydroxamic acid.
19540	siderophore biosynthetic process from catechol	P	The chemical reactions and pathways resulting in the formation of a siderophore from other compounds, including catechol.
19541	propionate metabolic process	P	The chemical reactions and pathways involving propionate, the anion derived from propionic (propanoic) acid, a carboxylic acid important in the energy metabolism of ruminants.
19542	propionate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of propionate, the anion derived from propionic acid.
19543	propionate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of propionate, the anion derived from propionic acid.
19544	arginine catabolic process to glutamate	P	The chemical reactions and pathways resulting in the breakdown of arginine into other compounds, including glutamate.
19545	arginine catabolic process to succinate	P	The chemical reactions and pathways resulting in the breakdown of arginine into other compounds, including succinate.
19546	arginine deiminase pathway	P	The chemical reactions and pathways resulting in the breakdown of arginine into other compounds, including ornithine and CO2, using the enzyme arginine deiminase.
19547	arginine catabolic process to ornithine	P	The chemical reactions and pathways resulting in the breakdown of arginine into other compounds, including ornithine.
19548	arginine catabolic process to spermine	P	The chemical reactions and pathways resulting in the breakdown of arginine into other compounds, including spermine.
19549	glutamate catabolic process to succinate via succinate semialdehyde	P	The chemical reactions and pathways resulting in the breakdown of glutamate into succinate, that includes the conversion of 4-aminobutyrate to succinate semialdehyde by the pyruvate-dependent gamma aminobutyrate (GABA) transaminase.
19550	glutamate catabolic process to aspartate	P	The chemical reactions and pathways resulting in the breakdown of glutamate into other compounds, including aspartate.
19551	glutamate catabolic process to 2-oxoglutarate	P	The chemical reactions and pathways resulting in the breakdown of glutamate into other compounds, including 2-oxoglutarate.
19552	glutamate catabolic process via 2-hydroxyglutarate	P	The anaerobic chemical reactions and pathways resulting in the breakdown of glutamate, via the intermediate 2-hydroxyglutarate, yielding energy in the form of ATP.
19553	glutamate catabolic process via L-citramalate	P	The chemical reactions and pathways resulting in the breakdown of glutamate, via the intermediate L-citramalate.
19554	glutamate catabolic process to oxaloacetate	P	The chemical reactions and pathways resulting in the breakdown of glutamate into other compounds, including oxaloacetate.
19555	glutamate catabolic process to ornithine	P	The chemical reactions and pathways resulting in the breakdown of glutamate into other compounds, including ornithine.
19556	histidine catabolic process to glutamate and formamide	P	The chemical reactions and pathways resulting in the breakdown of histidine into other compounds, including glutamate and formamide.
19557	histidine catabolic process to glutamate and formate	P	The chemical reactions and pathways resulting in the breakdown of histidine into other compounds, including glutamate and formate.
19558	histidine catabolic process to 2-oxoglutarate	P	The chemical reactions and pathways resulting in the breakdown of histidine into other compounds, including 2-oxoglutarate.
19559	histidine catabolic process to imidazol-5-yl-lactate	P	The chemical reactions and pathways resulting in the breakdown of histidine into other compounds, including imidazol-5-yl-lactate.
19560	histidine catabolic process to hydantoin-5-propionate	P	The chemical reactions and pathways resulting in the breakdown of histidine into other compounds, including hydantoin-5-propionate.
19561	anaerobic phenylalanine oxidation	P	The chemical reactions and pathways resulting in the breakdown of phenylalanine under anaerobic conditions; occurs via the intermediates phenylpyruvate and phenylacetaldehyde.
19562	phenylalanine catabolic process to phosphoenolpyruvate	P	The chemical reactions and pathways resulting in the breakdown of phenylalanine into other compounds, including phosphoenolpyruvate.
19563	glycerol catabolic process	P	The chemical reactions and pathways resulting in the breakdown of glycerol, 1,2,3-propanetriol, a sweet, hygroscopic, viscous liquid, widely distributed in nature as a constituent of many lipids.
19564	aerobic glycerol catabolic process	P	The chemical reactions and pathways resulting in the breakdown of glycerol, 1,2,3-propanetriol, in the presence of oxygen.
19566	arabinose metabolic process	P	The chemical reactions and pathways involving arabinose, arabino-pentose. L-Arabinose occurs both free, for example in the heartwood of many conifers, and in the combined state, as a constituent of plant hemicelluloses, bacterial polysaccharides etc. D-arabinose is a constituent of arabinonucleosides.
19567	arabinose biosynthetic process	P	The chemical reactions and pathways resulting in the formation of arabinose, arabino-pentose.
19568	arabinose catabolic process	P	The chemical reactions and pathways resulting in the breakdown of arabinose, arabino-pentose.
19569	L-arabinose catabolic process to xylulose 5-phosphate	P	The chemical reactions and pathways resulting in the breakdown of L-arabinose into other compounds, including xylulose 5-phosphate.
19570	L-arabinose catabolic process to 2-oxoglutarate	P	The chemical reactions and pathways resulting in the breakdown of L-arabinose into other compounds, including 2-oxoglutarate.
19571	D-arabinose catabolic process	P	The chemical reactions and pathways resulting in the breakdown of D-arabinose, the D-enantiomer of arabino-pentose.
19572	L-arabinose catabolic process	P	The chemical reactions and pathways resulting in the breakdown of L-arabinose, the L-enantiomer of arabino-pentose.
19573	D-arabinose catabolic process to xylulose 5-phosphate	P	The chemical reactions and pathways resulting in the breakdown of D-arabinose to form xylulose 5-phosphate. D-arabinose is converted into D-ribulose, which is phosphorylated to ribulose-5-phosphate, which is isomerized to give D-xylulose-5-phosphate.
19574	sucrose catabolic process via 3'-ketosucrose	P	The chemical reactions and pathways resulting in the breakdown of sucrose, which proceeds via the conversion of sucrose to 3'-ketosucrose. 3'-ketosucrose is hydrolyzed to 3-ketoglucose and fructose, and the 3-ketoglucose is then be converted to glucose.
19576	aerobic fructose catabolic process	P	The chemical reactions and pathways resulting in the breakdown of fructose that occurs in the presence of oxygen.
19577	aldaric acid metabolic process	P	The chemical reactions and pathways involving aldaric acid, any dicarboxylic acid formed by oxidation of by the terminal groups of an aldose to carboxyl group.
19578	aldaric acid biosynthetic process	P	The chemical reactions and pathways resulting in the formation of aldaric acid, any dicarboxylic acid formed by oxidation of by the terminal groups of an aldose to carboxyl group.
19579	aldaric acid catabolic process	P	The chemical reactions and pathways resulting in the breakdown of aldaric acid, any dicarboxylic acid formed by oxidation of by the terminal groups of an aldose to carboxyl group.
19580	galactarate metabolic process	P	The chemical reactions and pathways involving galactarate, an anion of galactaric acid, the meso-aldaric acid derived from both D- and L-galactose.
19583	galactonate metabolic process	P	The chemical reactions and pathways involving galactonate, the anion of galactonic acid, an organic acid derived from the sugar galactose.
19584	galactonate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of galactonate, the anion of galactonic acid.
19585	glucuronate metabolic process	P	The chemical reactions and pathways involving glucuronate, any salt or ester of glucuronic acid, the uronic acid formally derived from glucose by oxidation of the hydroxymethylene group at C-6 to a carboxyl group.
19586	galacturonate metabolic process	P	The chemical reactions and pathways involving galacturonate, the anion of galacturonic acid, the uronic acid formally derived from galactose by oxidation of the hydroxymethylene group at C-6 to a carboxyl group.
19588	anaerobic glycerol catabolic process	P	The anaerobic chemical reactions and pathways resulting in the breakdown of glycerol, yielding energy in the form of ATP.
19589	anaerobic glycerol catabolic process to propane-1,3-diol	P	The anaerobic chemical reactions and pathways resulting in the breakdown of glycerol into propane-1,3-diol and water.
19590	L-arabitol catabolic process to xylulose 5-phosphate	P	The chemical reactions and pathways resulting in the breakdown of L-arabitol to form xylulose 5-phosphate. L-arabitol is converted into L-xylulose, which is then phosphorylated to L-xylulose-5-phosphate. This is converted to D-xylulose-5-phosphate via the intermediate L-ribulose-5-phosphate.
19592	mannitol catabolic process	P	The chemical reactions and pathways resulting in the breakdown of mannitol, the alditol derived from D-mannose by reduction of the aldehyde group.
19593	mannitol biosynthetic process	P	The chemical reactions and pathways resulting in the formation of mannitol, the alditol derived from D-mannose by reduction of the aldehyde group.
19594	mannitol metabolic process	P	The chemical reactions and pathways involving mannitol, the alditol derived from D-mannose by reduction of the aldehyde group.
19595	non-phosphorylated glucose catabolic process	P	The chemical reactions and pathways resulting in the breakdown of non-phosphorylated forms of glucose.
19596	mandelate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of mandelate, the anion of mandelic acid. Mandelic acid (alpha-hydroxybenzeneacetic acid) is an 8-carbon alpha-hydroxy acid (AHA) that is used in organic chemistry and as a urinary antiseptic.
19597	(R)-mandelate catabolic process to benzoate	P	The chemical reactions and pathways resulting in the breakdown of (R)-mandelate into other compounds, including benzoate.
19598	(R)-mandelate catabolic process to catechol	P	The chemical reactions and pathways resulting in the breakdown of (R)-mandelate into other compounds, including catechol.
19599	(R)-4-hydroxymandelate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of (R)-4-hydroxymandelate, the anion of (R)-4-hydroxymandelic acid.
19600	toluene oxidation	P	The chemical reactions and pathways resulting in the loss of electrons from one or more atoms in toluene.
19601	toluene oxidation via 2-hydroxytoluene	P	The degradation of toluene to form pyruvate and acetaldehyde; the first step in the pathway is the oxidation of toluene to form 2-hydroxytoluene (o-cresol).
19602	toluene oxidation via 3-hydroxytoluene	P	The degradation of toluene to form pyruvate and acetaldehyde; the first step in the pathway is the oxidation of toluene to form 3-hydroxytoluene (m-cresol).
19603	toluene oxidation via 4-hydroxytoluene	P	The degradation of toluene to form p-hydroxybenzoate; the first step in the pathway is the oxidation of toluene to form 4-hydroxytoluene (4-cresol).
19604	toluene oxidation to catechol	P	The formation from toluene of catechol, dihydroxybenzene, by successive oxidations followed by loss of carbon dioxide (CO2).
19605	butyrate metabolic process	P	The chemical reactions and pathways involving any butyrate, the anions of butyric acid (butanoic acid), a saturated, unbranched aliphatic acid.
19606	2-oxobutyrate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of 2-oxobutyrate, the anion of the organic acid 2-oxobutyric acid, which contains a ketone group on carbon 2.
19607	phenylethylamine catabolic process	P	The chemical reactions and pathways resulting in the breakdown of phenylethylamine, an amine with pharmacological properties similar to those of amphetamine, occurs naturally as a neurotransmitter in the brain, and is present in chocolate and oil of bitter almonds.
19608	nicotine catabolic process	P	The chemical reactions and pathways resulting in the breakdown of nicotine, (S)(-)-3-(1-methyl-2-pyrrolidinyl)pyridine.
19609	3-hydroxyphenylacetate metabolic process	P	The chemical reactions and pathways involving 3-hydroxyphenylacetate, 1,3-benzenediol monoacetate, also known as resorcinol monoacetate.
19610	3-hydroxyphenylacetate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of 3-hydroxyphenylacetate, 1,3-benzenediol monoacetate, also known as resorcinol monoacetate.
19611	4-toluenecarboxylate metabolic process	P	The chemical reactions and pathways involving 4-toluenecarboxylate, 4-methylbenzenecarboxylate, the anion of carboxylic acid attached to a methylbenzene molecule.
19612	4-toluenecarboxylate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of 4-toluenecarboxylate, 4-methylbenzenecarboxylate, the anion of carboxylic acid attached to a methylbenzene molecule.
19614	catechol-containing compound catabolic process	P	The chemical reactions and pathways resulting in the breakdown of catechol-containing compounds. Catechol is a compound containing a pyrocatechol nucleus or substituent.
19615	catechol catabolic process, ortho-cleavage	P	The chemical reactions and pathways resulting in the breakdown of catechol via the ortho-cleavage pathway, in which the catechol aromatic ring is broken between the two carbon atoms bearing hydroxyl groups.
19616	catechol catabolic process, meta-cleavage	P	The chemical reactions and pathways resulting in the breakdown of catechol via the meta-cleavage pathway, in which the catechol aromatic ring is broken between a hydroxylated carbon atom and an adjacent unsubstituted carbon atom.
19617	protocatechuate catabolic process, meta-cleavage	P	The chemical reactions and pathways resulting in the breakdown of protocatechuate, the anion of 3,4-dihydroxybenzoic acid, to yield oxaloacetate and pyruvate.
19618	protocatechuate catabolic process, ortho-cleavage	P	The chemical reactions and pathways resulting in the breakdown of protocatechuate, the anion of 3,4-dihydroxybenzoic acid, to yield beta-ketoadipate.
19619	3,4-dihydroxybenzoate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of 3,4-dihydroxybenzoate.
19620	aerobic benzoate metabolic process	P	The chemical reactions and pathways involving benzoate, the anion of benzoic acid (benzenecarboxylic acid) that occur in the presence of oxygen.
19621	creatinine catabolic process to formate	P	The chemical reactions and pathways resulting in the breakdown of creatinine into other compounds, including formate.
19622	3-(3-hydroxy)phenylpropionate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of 3-(3-hydroxy)phenylpropionate, a hydroxylated derivative of phenylpropionate.
19623	atrazine catabolic process to urea	P	The chemical reactions and pathways resulting in the breakdown of atrazine, a triazine ring-containing herbicide, into urea.
19624	atrazine catabolic process to isopropylamine	P	The chemical reactions and pathways resulting in the breakdown of atrazine, a triazine ring-containing herbicide, into isopropylamine.
19625	atrazine catabolic process to cyanuric acid	P	The chemical reactions and pathways resulting in the breakdown of atrazine, a triazine ring-containing herbicide, into cyanuric acid.
19626	short-chain fatty acid catabolic process	P	The chemical reactions and pathways resulting in the breakdown of fatty acids with a chain length of less than C6.
19627	urea metabolic process	P	The chemical reactions and pathways involving urea, the water soluble compound O=C-(NH2)2.
19628	urate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of urate, the anion of uric acid, 2,6,8-trioxypurine.
19629	propionate catabolic process, 2-methylcitrate cycle	P	The chemical reactions and pathways resulting in the breakdown of propionate that occurs in the 2-methylcitrate cycle.
19630	quinate metabolic process	P	The chemical reactions and pathways involving quinate, the anion of quinic acid. The acid occurs commonly in plants, either free or as esters, and is used as a medicine.
19631	quinate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of quinate, the anion of quinic acid.
19632	shikimate metabolic process	P	The chemical reactions and pathways involving shikimate, (3R,4S,5R)--3,4,5-trihydroxycyclohex-1-ene-1-carboxylate, the anion of shikimic acid. It is an important intermediate in the biosynthesis of aromatic amino acids.
19633	shikimate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of shikimate, (3R,4S,5R)--3,4,5-trihydroxycyclohex-1-ene-1-carboxylate, the anion of shikimic acid.
19634	organic phosphonate metabolic process	P	The chemical reactions and pathways involving phosphonates, any organic compounds containing one or more C-PO(OH)2 or C-PO(OR)2 (with R=alkyl, aryl) groups. Metabolism of phosphonic acid itself, an inorganic compound without the biochemically relevant C-P bond, is not included.
19635	2-aminoethylphosphonate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of 2-aminoethylphosphonate, also known as ciliatine.
19636	phosphonoacetate metabolic process	P	The chemical reactions and pathways involving phosphonoacetate, C2H4PO5, a substance composed of an acetate and a phosphonic acid residue.
19637	organophosphate metabolic process	P	The chemical reactions and pathways involving organophosphates, any phosphate-containing organic compound.
19638	6-hydroxycineole metabolic process	P	The chemical reactions and pathways involving 6-hydroxycineole (6-hydroxy-1,8-epoxy-p-menthane), a hydrocarbon with the formula C10H18O2.
19639	6-hydroxycineole catabolic process	P	The chemical reactions and pathways resulting in the breakdown of 6-hydroxycineole (6-hydroxy-1,8-epoxy-p-menthane), a hydrocarbon with the formula C10H18O2.
19640	glucuronate catabolic process to xylulose 5-phosphate	P	The chemical reactions and pathways resulting in the breakdown of glucuronate into other compounds, including xylulose 5-phosphate.
19643	reductive tricarboxylic acid cycle	P	A pathway leading to the fixation of two molecules of CO2 and the production of one molecule of acetyl-CoA; essentially the oxidative TCA cycle running in reverse. Acetyl-CoA is reductively carboxylated to pyruvate, from which all other central metabolites can be formed. Most of the enzymes of reductive and oxidative TCA cycle are shared, with the exception of three key enzymes that allow the cycle to run in reverse: ATP citrate lyase, 2-oxoglutarate:ferredoxin oxidoreductase, and fumarate reductase. 2-oxoglutarate:ferredoxin oxidoreductase catalyzes the carboxylation of succinyl-CoA to 2-oxoglutarate, ATP citrate lyase the ATP-dependent cleavage of citrate to acetyl-CoA and oxaloacetate, and fumarate reductase the reduction of fumarate forming succinate.
19645	anaerobic electron transport chain	P	A process in which a series of electron carriers operate together to transfer electrons from donors such as NADH and FADH2 to any of several different terminal electron acceptors other than oxygen to generate a transmembrane electrochemical gradient.
19646	aerobic electron transport chain	P	A process in which a series of electron carriers operate together to transfer electrons from donors such as NADH and FADH2 to oxygen to generate a transmembrane electrochemical gradient.
19647	formaldehyde assimilation via ribulose monophosphate cycle	P	The pathway in which formaldehyde is used as a carbon source in the ribulose monophosphate cycle. Methanotrophic bacteria produce formaldehyde from the oxidation of methane and methanol, and then assimilate it via the ribulose monophosphate cycle to form intermediates of the central metabolic routes that are subsequently used for biosynthesis of cell material. Three molecules of formaldehyde are assimilated, forming a three-carbon intermediate of central metabolism; in this pathway, all cellular carbon is assimilated at the oxidation level of formaldehyde.
19648	formaldehyde assimilation via xylulose monophosphate cycle	P	The pathway in which formaldehyde is used as a carbon source in the xylulose monophosphate cycle. Methylotrophic yeasts, but not bacteria, utilize the xylulose monophosphate cycle to fix formaldehyde and convert it into metabolically useful organic compounds.
19649	formaldehyde assimilation	P	The pathways in which formaldehyde is processed and used as a carbon source for the cell.
19650	glycolytic fermentation to butanediol	P	The anaerobic chemical reactions and pathways resulting in the breakdown of glucose into butanediol; effected by some members of the Enterobacteriaceae, e.g. Enterobacter, Erwinia, Klebsiella, and Serratia.
19651	citrate catabolic process to diacetyl	P	The anaerobic chemical reactions and pathways resulting in the breakdown of citrate to diacetyl, yielding energy in the form of ATP.
19652	lactate fermentation to propionate and acetate	P	The anaerobic enzymatic conversion of lactate to propionate, concomitant with the oxidation of lactate to acetate and CO2 and yielding energy in the form of adenosine triphosphate (ATP).
19653	anaerobic purine nucleobase catabolic process	P	The anaerobic chemical reactions and pathways resulting in the breakdown of purine nucleobases, yielding energy in the form of ATP.
19654	acetate fermentation	P	The anaerobic chemical reactions and pathways resulting in the breakdown of acetate, yielding energy in the form of ATP.
19655	glycolytic fermentation to ethanol	P	The anaerobic chemical reactions and pathways resulting in the breakdown of glucose; it is converted into ethanol and carbon dioxide (CO2), producing two molecules of ATP for each molecule of glucose.
19656	glucose catabolic process to D-lactate and ethanol	P	The anaerobic chemical reactions and pathways resulting in the enzymatic breakdown of D-glucose to D-lactate and ethanol, yielding energy in the form of adenosine triphosphate (ATP) at the rate of one ATP per glucose molecule.
19657	glycolytic fermentation to propionate	P	Glycolytic fermentation resulting in the catabolism of glucose to propionate, yielding energy in the form of ATP; an alternative to the acrylate pathway to produce propionate.
19658	glucose fermentation to lactate and acetate	P	The anaerobic chemical reactions and pathways resulting in the breakdown of glucose to lactate and acetate, yielding energy in the form of ATP.
19659	glucose catabolic process to lactate	P	The anaerobic enzymatic chemical reactions and pathways resulting in the breakdown of glucose to lactate, and possibly ethanol, yielding energy in the form of adenosine triphosphate (ATP).
19660	glycolytic fermentation	P	Fermentation that includes the anaerobic conversion of glucose to pyruvate via the glycolytic pathway.
19661	glucose catabolic process to lactate via pyruvate	P	The anaerobic enzymatic chemical reactions and pathways resulting in the breakdown of glucose to lactate, via canonical glycolysis, yielding energy in the form of adenosine triphosphate (ATP).
19662	non-glycolytic fermentation	P	Fermentation that does not include the anaerobic conversion of glucose to pyruvate via the glycolytic pathway.
19664	mixed acid fermentation	P	The anaerobic chemical reactions and pathways resulting in the breakdown of glucose into ethanol, lactate, formate, succinate, and acetate, yielding energy in the form of ATP.
19665	anaerobic amino acid catabolic process	P	The anaerobic chemical reactions and pathways resulting in the breakdown of amino acids, yielding energy in the form of ATP.
19666	nitrogenous compound fermentation	P	The anaerobic chemical reactions and pathways resulting in the breakdown of a nitrogen-containing compound, yielding energy in the form of ATP.
19667	anaerobic L-alanine catabolic process	P	The anaerobic chemical reactions and pathways resulting in the breakdown of L-alanine, yielding energy in the form of ATP.
19668	anaerobic catabolism of pairs of amino acids	P	The anaerobic chemical reactions and pathways resulting in the breakdown of amino acids; in these reactions, one amino acid is oxidised (acts as an electron donor) and a different amino acid is reduced (acts as an electron acceptor); oxidation of the electron-donating amino acid yields energy in the form of ATP.
19669	anaerobic glycine catabolic process	P	The anaerobic chemical reactions and pathways resulting in the breakdown of glycine, yielding energy in the form of ATP.
19670	anaerobic glutamate catabolic process	P	The anaerobic chemical reactions and pathways resulting in the breakdown of glutamate, yielding energy in the form of ATP.
19671	glutamate catabolic process via mesaconate and citramalate	P	The anaerobic chemical reactions and pathways resulting in the breakdown of glutamate via the intermediates mesaconate and S-citramalate, yielding energy in the form of ATP.
19672	ethanol-acetate fermentation to butyrate and caproate	P	The anaerobic chemical reactions and pathways resulting in the breakdown of ethanol and acetate to butyrate and caproate, yielding energy in the form of ATP.
19673	GDP-mannose metabolic process	P	The chemical reactions and pathways involving GDP-mannose, a substance composed of mannose in glycosidic linkage with guanosine diphosphate.
19674	NAD metabolic process	P	The chemical reactions and pathways involving nicotinamide adenine dinucleotide (NAD), a coenzyme present in most living cells and derived from the B vitamin nicotinic acid.
19676	ammonia assimilation cycle	P	The pathway by which ammonia is processed and incorporated into a cell. In an energy-rich (glucose-containing), nitrogen-poor environment, glutamine synthetase and glutamate synthase form an ammonia assimilatory cycle, in which ammonia is incorporated into L-glutamate to form L-glutamine, which then combines with alpha-ketoglutarate to regenerate L-glutamate. This ATP-dependent cycle is essential for nitrogen-limited growth and for steady-state growth with some sources of nitrogen.
19677	NAD catabolic process	P	The chemical reactions and pathways resulting in the breakdown of nicotinamide adenine dinucleotide, a coenzyme present in most living cells and derived from the B vitamin nicotinic acid; catabolism may be of either the oxidized form, NAD, or the reduced form, NADH.
19678	propionate metabolic process, methylmalonyl pathway	P	The chemical reactions and pathways involving propionate that occur in the methylmalonyl pathway.
19679	propionate metabolic process, methylcitrate cycle	P	The chemical reactions and pathways involving propionate that occur in the methylcitrate cycle.
19680	L-methylmalonyl-CoA biosynthetic process	P	The chemical reactions and pathways resulting in the formation of L-methylmalonyl-CoA, the L-enantiomer of 2-carboxypropanoyl-CoA.
19681	acetyl-CoA assimilation pathway	P	The pathways by which acetyl-CoA is processed and converted into alpha-ketoglutarate (2-oxoglutarate); methanogenic archaea use these pathways to assimilate acetyl-CoA into the cell.
19682	glyceraldehyde-3-phosphate metabolic process	P	The chemical reactions and pathways involving glyceraldehyde-3-phosphate, an important intermediate in glycolysis.
19683	glyceraldehyde-3-phosphate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of glyceraldehyde-3-phosphate, an important intermediate in glycolysis.
19684	photosynthesis, light reaction	P	The light reactions of photosynthesis, which take place in photosystems II and I. Light energy is harvested and used to power the transfer of electrons among a series of electron donors and acceptors. The final electron acceptor is NADP+, which is reduced to NADPH. NADPH generated from light reactions is used in sugar synthesis in dark reactions. Light reactions also generate a proton motive force across the thylakoid membrane, and the proton gradient is used to synthesize ATP. There are two chemical reactions involved in the light reactions: water oxidation in photosystem II, and NADP reduction in photosystem I.
19685	photosynthesis, dark reaction	P	A complex cycle of enzyme-mediated reactions which catalyzes the reduction of carbon dioxide to sugar. As well as carbon dioxide the cycle requires reducing power in the form of reduced nicotinamide adenine dinucleotide phosphate (NADP) and chemical energy in the form of adenosine triphosphate (ATP). The reduced NADP (NADPH) and ATP are produced by the 'light' reactions.
19686	purine nucleoside interconversion	P	The chemical reactions and pathways by which a purine nucleoside is synthesized from another purine nucleoside.
19687	pyruvate biosynthetic process from acetate	P	The chemical reactions and pathways resulting in the formation of pyruvate from other compounds, including acetate.
19688	purine deoxyribonucleoside interconversion	P	The chemical reactions and pathways by which a purine deoxyribonucleoside is synthesized from another purine deoxyribonucleoside.
19689	pyrimidine nucleoside interconversion	P	The chemical reactions and pathways by which a pyrimidine nucleoside is synthesized from another pyrimidine nucleoside.
19690	pyrimidine deoxyribonucleoside interconversion	P	The chemical reactions and pathways by which a pyrimidine deoxyribonucleoside is synthesized from another deoxyribopyrimidine nucleoside.
19692	deoxyribose phosphate metabolic process	P	The chemical reactions and pathways involving deoxyribose phosphate, the phosphorylated sugar 2-deoxy-erythro-pentose.
19693	ribose phosphate metabolic process	P	The chemical reactions and pathways involving ribose phosphate, any phosphorylated ribose sugar.
19694	alkanesulfonate metabolic process	P	The chemical reactions and pathways involving alkanesulfonates, the anion of alkanesulfonic acids, sulfonic acid derivatives containing an aliphatic hydrocarbon group.
19695	choline metabolic process	P	The chemical reactions and pathways involving choline (2-hydroxyethyltrimethylammonium), an amino alcohol that occurs widely in living organisms as a constituent of certain types of phospholipids and in the neurotransmitter acetylcholine.
19696	toluene oxidation via toluene-cis-1,2-dihydrodiol	P	The degradation of toluene to form pyruvate and acetaldehyde; the first step in the pathway is the oxidation of toluene to form toluene-cis-1,2-dihydrodiol.
19697	L-xylitol catabolic process to xylulose 5-phosphate	P	The chemical reactions and pathways resulting in the breakdown of L-xylitol to form xylulose 5-phosphate. L-xylitol is converted into L-xylulose, which is then phosphorylated to L-xylulose-5-phosphate. This is converted to D-xylulose-5-phosphate via the intermediate L-ribulose-5-phosphate.
19698	D-galacturonate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of D-galacturonate, the D-enantiomer of galacturonate, the anion of galacturonic acid.
19700	organic phosphonate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of phosphonates, any organic compound containing one or more C-PO(OH)2 or C-PO(OR)2 (with R=alkyl, aryl) groups. Catabolism of phosphonic acid itself, an inorganic compound without the biochemically relevant C-P bond, is not included.
19701	peptidyl-arginine N5-methylation	P	The methylation of peptidyl-arginine on the internal nitrogen-5 (N5) atom (also called delta-nitrogen) to form peptidyl-N5-methyl-L-arginine.
19702	protein-arginine N5-methyltransferase activity	F	Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to the delta-nitrogen atom of peptidyl-arginine residues. The reaction is S-adenosyl-L-methionine + [protein]-L-arginine = S-adenosyl-L-homocysteine + [protein]-N5-methyl-L-arginine.
19703	coenzyme A-peptidyl-cysteine covalent linking	P	The covalent linkage of coenzyme A and peptidyl-cysteine to form L-cysteine coenzyme A disulfide.
19704	peptidyl-S-myristoyl-L-cysteine biosynthetic process from peptidyl-cysteine	P	The modification of peptidyl-cysteine to form peptidyl-S-myristoyl-L-cysteine.
19705	protein-cysteine S-myristoyltransferase activity	F	Catalysis of the transfer of a myristoyl group to a sulfur atom on a cysteine residue of a protein molecule.
19706	protein-cysteine S-palmitoyltransferase activity	F	Catalysis of the transfer of a palmitoyl group to a sulfur atom on the cysteine of a protein molecule.
19707	protein-cysteine S-acyltransferase activity	F	Catalysis of the transfer of an acyl group to a sulfur atom on the cysteine of a protein molecule.
19708	peptidyl-glycine cholesteryl ester biosynthesis from peptidyl-glycine	P	The synthesis of peptidyl-glycine cholest-5-en-3-beta-ol ester at the carboxy-terminus of autolytically cleaved proteins.
19709	iron incorporation into iron-sulfur cluster via pentakis-L-cysteinyl L-histidino nickel tetrairon pentasulfide	P	The incorporation of iron into a nickel-iron-sulfur cluster via pentakis-L-cysteinyl L-histidino nickel tetrairon pentasulfide, found in carbon monoxide dehydrogenase.
19710	peptidyl-asparagine methylation	P	The methylation of peptidyl-asparagine to form peptidyl-N4-methyl-L-asparagine or peptidyl-N4,N4-dimethyl-L-asparagine.
19711	peptidyl-beta-carboxyaspartic acid biosynthetic process from peptidyl-aspartic acid	P	The chemical reactions and pathways resulting in the formation of peptidyl-beta-carboxyaspartic acid from other compounds, including peptidyl-aspartic acid.
19712	peptidyl-L-glutamic acid 5-methyl ester biosynthetic process from glutamic acid	P	The methyl esterification of peptidyl-glutamic acid.
19713	peptidyl-L-glutamic acid 5-methyl ester biosynthetic process from glutamine	P	The coupled methyl esterification and deamidation of peptidyl-glutamine.
19714	peptidyl-glutamine esterification	P	The addition of an ester group to a glutamine residue in a protein.
19715	peptidyl-aspartic acid hydroxylation to form L-erythro-beta-hydroxyaspartic acid	P	The hydroxylation of peptidyl-aspartic acid to form peptidyl-L-erythro-beta-hydroxyaspartic acid; catalyzed by peptide-aspartate beta-dioxygenase (EC:1.14.11.16).
19716	N-terminal peptidyl-alanine monomethylation	P	The monomethylation of the N-terminal alanine of proteins to form the derivative peptidyl-N-methyl-L-alanine.
19720	Mo-molybdopterin cofactor metabolic process	P	The chemical reactions and pathways involving the Mo-molybdopterin cofactor, essential for the catalytic activity of some enzymes. The cofactor consists of a mononuclear molybdenum (Mo) ion coordinated by one or two molybdopterin ligands.
19722	calcium-mediated signaling	P	Any intracellular signal transduction in which the signal is passed on within the cell via calcium ions.
19724	B cell mediated immunity	P	Any process involved with the carrying out of an immune response by a B cell, through, for instance, the production of antibodies or cytokines, or antigen presentation to T cells.
19725	cellular homeostasis	P	Any process involved in the maintenance of an internal steady state at the level of the cell.
19726	mevaldate reductase (NADPH) activity	F	Catalysis of the reaction: (R)-mevalonate + NADP(+) = H(+) + mevaldate + NADPH.
19727	mevaldate reductase (NAD+) activity	F	Catalysis of the reaction: (R)-mevalonate + NAD(+) = H(+) + mevaldate + NADH.
19728	peptidyl-allysine oxidation to 2-aminoadipic acid	P	The oxidation of allysine to 2-aminoadipic acid.
19729	peptide cross-linking via 2-imino-glutaminyl-5-imidazolinone glycine	P	The formation of the fluorescent protein FP583 chromophore cross-link from the alpha-carboxyl carbon of residue n, a glutamine, to the alpha-amino nitrogen of residue n+2, a glycine, and a dehydration to form a double bond to the alpha-amino nitrogen of residue n+1. This cross-linking is coupled with a dehydrogenation of residue n+1 to form a double bond between the alpha and beta carbons.
19730	antimicrobial humoral response	P	An immune response against microbes mediated through a body fluid. Examples of this process are seen in the antimicrobial humoral response of Drosophila melanogaster and Mus musculus.
19731	antibacterial humoral response	P	An immune response against bacteria mediated through a body fluid. Examples of this process are the antibacterial humoral responses in Mus musculus and Drosophila melanogaster.
19732	antifungal humoral response	P	An immune response against a fungus mediated through a body fluid. An example of this process is the antifungal humoral response in Drosophila melanogaster.
19736	peptidyl-sarcosine incorporation	P	The incorporation of sarcosine (N-methylglycine) into non-coded peptides.
19740	nitrogen utilization	P	A series of processes that forms an integrated mechanism by which a cell or an organism detects the depletion of primary nitrogen source, usually ammonia, and then activates genes to scavenge the last traces of the primary nitrogen source and to transport and metabolize alternative nitrogen sources. The utilization process begins when the cell or organism detects nitrogen levels, includes the activation of genes whose products detect, transport or metabolize nitrogen-containing substances, and ends when nitrogen is incorporated into the cell or organism's metabolism.
19741	pentacyclic triterpenoid catabolic process	P	The chemical reactions and pathways resulting in the breakdown of pentacyclic triterpenoid compounds, terpenoids with six isoprene units and 5 carbon rings.
19742	pentacyclic triterpenoid metabolic process	P	The chemical reactions and pathways involving pentacyclic triterpenoid compounds, terpenoids with six isoprene units and 5 carbon rings.
19743	hopanoid catabolic process	P	The chemical reactions and pathways resulting in the breakdown of hopanoids, pentacyclic sterol-like compounds based on the hopane nucleus.
19744	hopanoid metabolic process	P	The chemical reactions and pathways involving hopanoids, pentacyclic sterol-like compounds based on the hopane nucleus.
19745	pentacyclic triterpenoid biosynthetic process	P	The chemical reactions and pathways resulting in the formation of pentacyclic triterpenoid compounds, terpenoids with six isoprene units and 5 carbon rings.
19746	hopanoid biosynthetic process	P	The chemical reactions and pathways resulting in the formation of hopanoids, pentacyclic sterol-like compounds based on the hopane nucleus.
19747	regulation of isoprenoid metabolic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving isoprenoids.
19748	secondary metabolic process	P	The chemical reactions and pathways resulting in many of the chemical changes of compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon. In multicellular organisms secondary metabolism is generally carried out in specific cell types, and may be useful for the organism as a whole. In unicellular organisms, secondary metabolism is often used for the production of antibiotics or for the utilization and acquisition of unusual nutrients.
19749	cytoskeleton-dependent cytoplasmic transport, nurse cell to oocyte	P	The directed movement of substances along cytoskeletal elements, such as microfilaments or microtubules, from a nurse cell to an oocyte.
19750	chloroplast localization	P	Any process in which a chloroplast is transported to, and/or maintained in, a specific location within the cell. A chloroplast is a chlorophyll-containing plastid found in cells of algae and higher plants.
19751	polyol metabolic process	P	The chemical reactions and pathways involving a polyol, any alcohol containing three or more hydroxyl groups attached to saturated carbon atoms.
19752	carboxylic acid metabolic process	P	The chemical reactions and pathways involving carboxylic acids, any organic acid containing one or more carboxyl (COOH) groups or anions (COO-).
19755	one-carbon compound transport	P	The directed movement of one-carbon compounds into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
19756	cyanogenic glycoside biosynthetic process	P	The chemical reactions and pathways resulting in the formation of cyanogenic glycosides, any glycoside containing a cyano group that is released as hydrocyanic acid on acid hydrolysis; such compounds occur in the kernels of various fruits.
19757	glycosinolate metabolic process	P	The chemical reactions and pathways involving glycosinolates, substituted thioglycosides found in rapeseed products and related cruciferae.
19758	glycosinolate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of glycosinolates, substituted thioglycosides found in rapeseed products and related cruciferae.
19759	glycosinolate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of glycosinolates, substituted thioglycosides found in rapeseed products and related cruciferae.
19760	glucosinolate metabolic process	P	The chemical reactions and pathways involving glucosinolates, substituted thioglucosides found in rapeseed products and related cruciferae. They are metabolized to a variety of toxic products which are most likely the cause of hepatocytic necrosis in animals and humans.
19761	glucosinolate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of glucosinolates, substituted thioglucosides found in rapeseed products and related cruciferae.
19762	glucosinolate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of glucosinolates, substituted thioglucosides found in rapeseed products and related cruciferae.
19763	immunoglobulin receptor activity	F	Combining with the Fc region of an immunoglobulin protein and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
19766	IgA receptor activity	F	Combining with an immunoglobulin of an IgA isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
19767	IgE receptor activity	F	Combining with an immunoglobulin of the IgE isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
19768	high-affinity IgE receptor activity	F	Combining with high affinity with an immunoglobulin of the IgE isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
19769	low-affinity IgE receptor activity	F	Combining with low affinity with an immunoglobulin of the IgE isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
19770	IgG receptor activity	F	Combining with an immunoglobulin of an IgG isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
19771	high-affinity IgG receptor activity	F	Combining with high affinity with an immunoglobulin of an IgG isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
19772	low-affinity IgG receptor activity	F	Combining with low affinity with an immunoglobulin of an IgG isotype via the Fc region, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
19773	proteasome core complex, alpha-subunit complex	C	The proteasome core subcomplex that constitutes the two outer rings of the proteasome core complex. An example of this component is found in Mus musculus.
19774	proteasome core complex, beta-subunit complex	C	The proteasome core subcomplex that constitutes the two inner rings of the proteasome core complex. An example of this component is found in Mus musculus.
19775	FAT10 transferase activity	F	Catalysis of the transfer of FAT10 from one protein to another via the reaction X-FAT10 + Y --> Y-FAT10 + X, where both X-FAT10 and Y-FAT10 are covalent linkages.
19776	Atg8 ligase activity	F	Catalysis of the covalent attachment of the ubiquitin-like protein Atg8 to substrate molecules; phosphatidylethanolamine is a known substrate.
19777	Atg12 transferase activity	F	Catalysis of the transfer of ATG12 from one protein to another via the reaction X-ATG12 + Y --> Y-ATG12 + X, where both X-ATG12 and Y-ATG12 are covalent linkages.
19778	Atg12 activating enzyme activity	F	Catalysis of the activation of the small ubiquitin-related modifier APG12, through the formation of an ATP-dependent high-energy thiolester bond.
19779	Atg8 activating enzyme activity	F	Catalysis of the activation of the small ubiquitin-related modifier APG8, through the formation of an ATP-dependent high-energy thiolester bond.
19780	FAT10 activating enzyme activity	F	Catalysis of the activation of the small ubiquitin-related modifier FAT10, through the formation of an ATP-dependent high-energy thiolester bond.
19781	NEDD8 activating enzyme activity	F	Catalysis of the initiation of the NEDD8 (RUB1) conjugation cascade.
19782	ISG15 activating enzyme activity	F	Catalysis of the activation of the small ubiquitin-related modifier ISG15, through the formation of an ATP-dependent high-energy thiolester bond.
19783	ubiquitin-like protein-specific protease activity	F	Catalysis of the hydrolysis of peptide or isopeptide bonds within small proteins such as ubiquitin or ubiquitin-like proteins (e.g. APG8, ISG15, NEDD8, SUMO), or between the small protein and a larger protein to which it has been conjugated.
19784	NEDD8-specific protease activity	F	Catalysis of the hydrolysis of NEDD8, a small ubiquitin-related modifier, from previously neddylated substrates.
19785	ISG15-specific protease activity	F	Catalysis of the hydrolysis of ISG15, a small ubiquitin-related modifier, from previously modified substrates.
19786	Atg8-specific protease activity	F	Catalysis of the hydrolysis of APG8, a small ubiquitin-related modifier.
19787	ubiquitin-like protein transferase activity	F	Catalysis of the transfer of a ubiquitin-like from one protein to another via the reaction X-ULP + Y --> Y-ULP + X, where both X-ULP and Y-ULP are covalent linkages. ULP represents a ubiquitin-like protein.
19788	NEDD8 transferase activity	F	Catalysis of the transfer of NEDD8 from one protein to another via the reaction X-NEDD8 + Y --> Y-NEDD8 + X, where both X-NEDD8 and Y-NEDD8 are covalent linkages.
19789	SUMO transferase activity	F	Catalysis of the transfer of SUMO from one protein to another via the reaction X-SUMO + Y --> Y-SUMO + X, where both X-SUMO and Y-SUMO are covalent linkages.
19797	procollagen-proline 3-dioxygenase activity	F	Catalysis of the reaction: procollagen L-proline + 2-oxoglutarate + O2 = procollagen trans-3-hydroxy-L-proline + succinate + CO2.
19798	procollagen-proline dioxygenase activity	F	Catalysis of the reaction: procollagen L-proline + 2-oxoglutarate + O2 = procollagen trans-hydroxy-L-proline + succinate + CO2.
19799	tubulin N-acetyltransferase activity	F	Catalysis of the reaction: acetyl-CoA + (alpha-tubulin) L-lysine = CoA + (alpha-tubulin) N6-acetyl-L-lysine.
19800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan	P	The formation of a cross-link between peptide chains mediated by a chondroitin 4-sulfate glycosaminoglycan that originates from a typical O-glycosidic link to serine of one chain; the other chain is esterified, via the alpha-carbon of its C-terminal Asp, to C-6 of an internal N-acetylgalactosamine of the glycosaminoglycan chain.
19801	cyclization of asparagine involved in intein-mediated protein splicing	P	The cyclization of asparagine to yield an L-aspartimide (otherwise known as alpha-aminosuccinimide) residue at the C-terminus of an excised intein during protein splicing.
19802	cyclization of glutamine involved in intein-mediated protein splicing	P	The cyclization of glutamine to yield an L-glutamimide residue at the C-terminus of an excised intein during protein splicing.
19803	peptidyl-aspartic acid carboxylation	P	The carboxylation of peptidyl-aspartic acid to form peptidyl-L-beta-carboxyaspartic acid.
19805	quinolinate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of quinolinate, the anion of quinolinic acid, also known as 2,3-pyridinedicarboxylic acid.
19806	bromide peroxidase activity	F	Catalysis of the reaction: 2 R-H + 2 bromide + hydrogen peroxide = 2 R-Br + 2 H2O. Enzymes with this activity often accept other halide ions as substrates, including chloride and iodide.
19807	aspartoacylase activity	F	Catalysis of the reaction: N-acyl-L-aspartate + H2O = a fatty acid anion + L-aspartate.
19808	polyamine binding	F	Interacting selectively and non-covalently with polyamines, organic compounds containing two or more amino groups.
19809	spermidine binding	F	Interacting selectively and non-covalently with spermidine, N-(3-aminopropyl)-1,4-diaminobutane.
19810	putrescine binding	F	Interacting selectively and non-covalently with putrescine, 1,4-diaminobutane, the polyamine formed by decarboxylation of ornithine and the metabolic precursor of spermidine and spermine.
19811	cocaine binding	F	Interacting selectively and non-covalently with cocaine (2-beta-carbomethoxy-3-beta-benzoxytropane), an alkaloid obtained from dried leaves of the South American shrub Erythroxylon coca or by chemical synthesis.
19812	Type I site-specific deoxyribonuclease complex	C	A multisubunit complex composed of two copies of a restriction (R) subunit, two copies of a methylation (M) subunit, and one copy of a specificity (S) subunit. This complex recognizes specific short DNA sequences (through the S subunit), and binds to them. If the recognition site is hemimethylated, the complex acts as a methyltransferase which modifies the recognition site, using S-adenosylmethionine as the methyl donor. Only the M and S subunits are required for this reaction. If the complex binds to an unmethylated recognition site, then the complex translocates the DNA bidirectionally in an ATP-dependent manner. When the translocation is stalled by impact with another complex or unusual DNA structure, the enzyme functions as an endonuclease and cleavage of the DNA will occur, hundreds or thousands of base pairs away from the recognition site. These DNA restriction systems are used by bacteria to defend against phage and other foreign DNA that may enter a cell.
19813	Type III site-specific deoxyribonuclease complex	C	A heterodimeric enzyme complex composed of two subunits, Res and Mod, that functions as an endonuclease and cleaves DNA. Cleavage will only occur when there are two un-methylated copies of a specific recognition site in an inverse orientation on the DNA. Cleavage occurs at a specific distance away from one of the recognition sites. The Mod subunit can act alone as a methyltansferase. DNA restriction systems such as this are used by bacteria to defend against phage and other foreign DNA that may enter a cell.
19814	immunoglobulin complex	C	A protein complex that in its canonical form is composed of two identical immunoglobulin heavy chains and two identical immunoglobulin light chains, held together by disulfide bonds and sometimes complexed with additional proteins. An immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.
19815	B cell receptor complex	C	An immunoglobulin complex that is present in the plasma membrane of B cells and that in its canonical form is composed of two identical immunoglobulin heavy chains and two identical immunoglobulin light chains and a signaling subunit, a heterodimer of the Ig-alpha and Ig-beta proteins.
19817	vesicle fusion with peroxisome	P	The joining of the lipid bilayer membrane around a vesicle with the lipid bilayer membrane around the peroxisome.
19819	P1 peroxisome	C	A subform of peroxisome that corresponds to an intermediate in a peroxisome assembly pathway, which operates by conversion of peroxisomal subforms in the direction P1, P2 -> P3 -> P4 -> P5 -> P6. P1 peroxisomes are distinguished from the other subforms on the bases of buoyant density and protein content; they contain fewer peroxisomal proteins than the other subforms.
19820	P2 peroxisome	C	A subform of peroxisome that corresponds to an intermediate in a peroxisome assembly pathway, which operates by conversion of peroxisomal subforms in the direction P1, P2 -> P3 -> P4 -> P5 -> P6. P2 peroxisomes are distinguished from the other subforms on the bases of buoyant density and protein content; they are the least dense of the subforms observed.
19821	P3 peroxisome	C	A subform of peroxisome that corresponds to an intermediate in a peroxisome assembly pathway, which operates by conversion of peroxisomal subforms in the direction P1, P2 -> P3 -> P4 -> P5 -> P6. P3 peroxisomes are formed by fusion of P1 and P2 peroxisomes, and are distinguished from the other subforms on the bases of buoyant density and protein content.
19822	P4 peroxisome	C	A subform of peroxisome that corresponds to an intermediate in a peroxisome assembly pathway, which operates by conversion of peroxisomal subforms in the direction P1, P2 -> P3 -> P4 -> P5 -> P6. P4 peroxisomes are distinguished from the other subforms on the bases of buoyant density and protein content.
19823	P5 peroxisome	C	A subform of peroxisome that corresponds to an intermediate in a peroxisome assembly pathway, which operates by conversion of peroxisomal subforms in the direction P1, P2 -> P3 -> P4 -> P5 -> P6. P5 peroxisomes are distinguished from the other subforms on the bases of buoyant density and protein content.
19824	P6 peroxisome	C	A subform of peroxisome that corresponds to an intermediate in a peroxisome assembly pathway, which operates by conversion of peroxisomal subforms in the direction P1, P2 -> P3 -> P4 -> P5 -> P6. P6 peroxisomes are distinguished from the other subforms on the bases of buoyant density and protein content, and are equivalent to mature peroxisomes.
19825	oxygen binding	F	Interacting selectively and non-covalently with oxygen (O2).
19826	oxygen sensor activity	F	Interacting selectively and non-covalently with and responding, e.g. by conformational change, to changes in the cellular level of oxygen (O2).
19827	stem cell population maintenance	P	The process by which an organism or tissue maintains a population of stem cells of a single type. This can be achieved by a number of mechanisms: stem cell asymmetric division maintains stem cell numbers; stem cell symmetric division increases them; maintenance of a stem cell niche maintains the conditions for commitment to the stem cell fate for some types of stem cell; stem cells may arise de novo from other cell types.
19828	aspartic-type endopeptidase inhibitor activity	F	Stops, prevents or reduces the activity of aspartic-type endopeptidases, enzymes that catalyze the hydrolysis of nonterminal peptide bonds in a polypeptide chain; the optimum reaction pH is below 5 due to an aspartic residue involved in the catalytic process.
19829	cation-transporting ATPase activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + cation(out) = ADP + phosphate + cation(in).
19834	phospholipase A2 inhibitor activity	F	Stops, prevents or reduces the activity of the enzyme phospholipase A2.
19835	cytolysis	P	The rupture of cell membranes and the loss of cytoplasm.
19836	hemolysis by symbiont of host erythrocytes	P	The cytolytic destruction of red blood cells, with the release of intracellular hemoglobin, in the host organism by a symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction.
19838	growth factor binding	F	Interacting selectively and non-covalently with any growth factor, proteins or polypeptides that stimulate a cell or organism to grow or proliferate.
19840	isoprenoid binding	F	Interacting selectively and non-covalently with any isoprenoid compound, isoprene (2-methylbuta-1,3-diene) or compounds containing or derived from linked isoprene (3-methyl-2-butenylene) residues.
19841	retinol binding	F	Interacting selectively and non-covalently with retinol, vitamin A1, 2,6,6-trimethyl-1-(9'-hydroxy-3',7'-dimethylnona-1',3',5',7'-tetraenyl)cyclohex-1-ene, one of the three components that makes up vitamin A. Retinol is an intermediate in the vision cycle and it also plays a role in growth and differentiation.
19842	vitamin binding	F	Interacting selectively and non-covalently with a vitamin, one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body.
19843	rRNA binding	F	Interacting selectively and non-covalently with ribosomal RNA.
19852	L-ascorbic acid metabolic process	P	The chemical reactions and pathways involving L-ascorbic acid, (2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2,5-dihydrofuran-3-olate; L-ascorbic acid is vitamin C and has co-factor and anti-oxidant activities in many species.
19853	L-ascorbic acid biosynthetic process	P	The chemical reactions and pathways resulting in the formation of L-ascorbic acid; L-ascorbic acid ionizes to give L-ascorbate, (2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2,5-dihydrofuran-3-olate, which is required as a cofactor in the oxidation of prolyl residues to hydroxyprolyl, and other reactions.
19854	L-ascorbic acid catabolic process	P	The chemical reactions and pathways resulting in the breakdown of L-ascorbic acid; L-ascorbic acid ionizes to give L-ascorbate, (2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2,5-dihydrofuran-3-olate, which is required as a cofactor in the oxidation of prolyl residues to hydroxyprolyl, and other reactions.
19855	calcium channel inhibitor activity	F	Stops, prevents, or reduces the activity of a calcium channel.
19856	pyrimidine nucleobase biosynthetic process	P	The chemical reactions and pathways resulting in the formation of pyrimidine nucleobases, 1,3-diazine, organic nitrogenous bases.
19857	5-methylcytosine metabolic process	P	The chemical reactions and pathways involving 5-methylcytosine, a methylated base of DNA.
19858	cytosine metabolic process	P	The chemical reactions and pathways involving cytosine, 4-amino-2-hydroxypyrimidine, a pyrimidine derivative that is one of the five main bases found in nucleic acids; it occurs widely in cytidine derivatives.
19859	thymine metabolic process	P	The chemical reactions and pathways involving thymine, 5-methyluracil, one of the two major pyrimidine bases present (as thymidine) in DNA but not found in RNA other than (as ribothymidine) in transfer RNA, where it is a minor base.
19860	uracil metabolic process	P	The chemical reactions and pathways involving uracil, 2,4-dioxopyrimidine, one of the pyrimidine bases occurring in RNA, but not in DNA.
19862	IgA binding	F	Interacting selectively and non-covalently with an immunoglobulin of an IgA isotype.
19863	IgE binding	F	Interacting selectively and non-covalently with an immunoglobulin of the IgE isotype.
19864	IgG binding	F	Interacting selectively and non-covalently with an immunoglobulin of an IgG isotype.
19865	immunoglobulin binding	F	Interacting selectively and non-covalently with an immunoglobulin.
19866	organelle inner membrane	C	The inner, i.e. lumen-facing, lipid bilayer of an organelle envelope; usually highly selective to most ions and metabolites.
19867	outer membrane	C	The external membrane of Gram-negative bacteria or certain organelles such as mitochondria and chloroplasts; freely permeable to most ions and metabolites.
19869	chloride channel inhibitor activity	F	Stops, prevents, or reduces the activity of a chloride channel.
19870	potassium channel inhibitor activity	F	Stops, prevents, or reduces the activity of a potassium channel.
19871	sodium channel inhibitor activity	F	Stops, prevents, or reduces the activity of a sodium channel.
19872	streptomycin biosynthetic process	P	The chemical reactions and pathways resulting in the formation of streptomycin, a commonly used antibiotic in cell culture media; it acts only on prokaryotes and blocks transition from initiation complex to chain elongating ribosome.
19874	6-aminohexanoate-cyclic-dimer hydrolase activity	F	Catalysis of the reaction: 1,8-diazacyclotetradecane-2,9-dione + H(2)O = N-(6-aminohexanoyl)-6-aminohexanoate.
19875	6-aminohexanoate-dimer hydrolase activity	F	Catalysis of the reaction: N-(6-aminohexanoyl)-6-aminohexanoate + H2O = 2 6-aminohexanoate.
19876	nylon catabolic process	P	The chemical reactions and pathways resulting in the breakdown of nylon, a polymer where the main polymer chain comprises recurring amide groups; these compounds are generally formed from combinations of diamines, diacids and amino acids.
19877	diaminopimelate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of diaminopimelate, both as an intermediate in lysine biosynthesis and as a component (as meso-diaminopimelate) of the peptidoglycan of Gram-negative bacterial cell walls.
19878	lysine biosynthetic process via aminoadipic acid	P	The chemical reactions and pathways resulting in the formation of lysine by the aminoadipic pathway.
19879	peptidyl-thyronine biosynthetic process from peptidyl-tyrosine	P	The formation of peptidyl-thyronine from peptidyl-tyrosine in thyroglobulin by phenyl transfer coupled with the formation of peptidyl-dehydroalanine.
19882	antigen processing and presentation	P	The process in which an antigen-presenting cell expresses antigen (peptide or lipid) on its cell surface in association with an MHC protein complex.
19883	antigen processing and presentation of endogenous antigen	P	The process in which an antigen-presenting cell expresses antigen (peptide or lipid) of endogenous origin on its cell surface in association with an MHC protein complex.
19884	antigen processing and presentation of exogenous antigen	P	The process in which an antigen-presenting cell expresses antigen (peptide or lipid) of exogenous origin on its cell surface in association with an MHC protein complex.
19885	antigen processing and presentation of endogenous peptide antigen via MHC class I	P	The process in which an antigen-presenting cell expresses a peptide antigen of endogenous origin on its cell surface in association with an MHC class I protein complex. The peptide antigen is typically, but not always, processed from a whole protein. Class I here refers to classical class I molecules.
19886	antigen processing and presentation of exogenous peptide antigen via MHC class II	P	The process in which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC class II protein complex. The peptide antigen is typically, but not always, processed from a whole protein.
19887	protein kinase regulator activity	F	Modulates the activity of a protein kinase, an enzyme which phosphorylates a protein.
19888	protein phosphatase regulator activity	F	Modulates the activity of a protein phosphatase, an enzyme which catalyzes of the removal of a phosphate group from a protein substrate molecule.
19889	pteridine metabolic process	P	The chemical reactions and pathways involving pteridine, pyrazino(2,3-dipyrimidine), the parent structure of pterins and the pteroyl group.
19894	kinesin binding	F	Interacting selectively and non-covalently and stoichiometrically with kinesin, a member of a superfamily of microtubule-based motor proteins that perform force-generating tasks such as organelle transport and chromosome segregation.
19895	kinesin-associated mitochondrial adaptor activity	F	The activity of linking kinesins, cytoplasmic proteins responsible for moving vesicles and organelles towards the distal end of microtubules, to mitochondria.
19896	axonal transport of mitochondrion	P	The directed movement of mitochondria along microtubules in nerve cell axons.
19897	extrinsic component of plasma membrane	C	The component of a plasma membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
19898	extrinsic component of membrane	C	The component of a membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
19899	enzyme binding	F	Interacting selectively and non-covalently with any enzyme.
19900	kinase binding	F	Interacting selectively and non-covalently with a kinase, any enzyme that catalyzes the transfer of a phosphate group.
19901	protein kinase binding	F	Interacting selectively and non-covalently with a protein kinase, any enzyme that catalyzes the transfer of a phosphate group, usually from ATP, to a protein substrate.
19902	phosphatase binding	F	Interacting selectively and non-covalently with any phosphatase.
19903	protein phosphatase binding	F	Interacting selectively and non-covalently with any protein phosphatase.
19904	protein domain specific binding	F	Interacting selectively and non-covalently with a specific domain of a protein.
19905	syntaxin binding	F	Interacting selectively and non-covalently with a syntaxin, a SNAP receptor involved in the docking of synaptic vesicles at the presynaptic zone of a synapse.
19907	cyclin-dependent protein kinase activating kinase holoenzyme complex	C	A cyclin-dependent kinase activating kinase complex capable of activating cyclin-dependent kinases by threonine phosphorylation, thus regulating cell cycle progression. consists of a kinase, cyclin and optional assembly factors, in human CDK7, CCNH and MNAT1. CAK activity is itself regulated throughout the cell cycle by T-loop phosphorylation of its kinase component (CDK7 in human). Phosphorylation of serine residues during mitosis inactivates the enzyme. Also capable of CAK phosphorylating the carboxyl-terminal domain (CTD) of RNA polymerase II and other transcription activating proteins, as part of the general transcription factor TFIIH.
19908	nuclear cyclin-dependent protein kinase holoenzyme complex	C	Cyclin-dependent protein kinase (CDK) complex found in the nucleus.
19909	[pyruvate dehydrogenase (lipoamide)] phosphatase regulator activity	F	Modification of the activity of the enzyme [pyruvate dehydrogenase (lipoamide)] phosphatase.
19910	mitochondrial pyruvate dehydrogenase (lipoamide) phosphatase complex	C	A mitochondrial complex of a regulatory and catalytic subunit that catalyzes the dephosphorylation and concomitant reactivation of the alpha subunit of the E1 component of the pyruvate dehydrogenase complex. An example of this component is found in Mus musculus.
19911	structural constituent of myelin sheath	F	The action of a molecule that contributes to the structural integrity of the myelin sheath of a nerve.
19912	cyclin-dependent protein kinase activating kinase activity	F	Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein; increases the activity of a cyclin-dependent protein kinase (CDK).
19914	cyclin-dependent protein kinase activating kinase regulator activity	F	Modulation of the activity of the enzyme cyclin-dependent protein kinase activating kinase.
19915	lipid storage	P	The accumulation and maintenance in cells or tissues of lipids, compounds soluble in organic solvents but insoluble or sparingly soluble in aqueous solvents. Lipid reserves can be accumulated during early developmental stages for mobilization and utilization at later stages of development.
19916	peptidyl-D-alanine racemization, direct	P	The racemization of peptidyl-alanine.
19917	peptidyl-D-alanine racemization via peptidyl-L-serine	P	The dehydration of peptidyl-serine, followed by hydrogenation to produce peptidyl-D-alanine.
19918	peptidyl-arginine methylation, to symmetrical-dimethyl arginine	P	The process of methylation of peptidyl-arginine to form peptidyl-N(omega),N'(omega)-dimethyl-L-arginine.
19919	peptidyl-arginine methylation, to asymmetrical-dimethyl arginine	P	The process of methylation of peptidyl-arginine to form peptidyl-N(omega),N(omega)-dimethyl-L-arginine.
19920	peptidyl-1-thioglycine biosynthetic process, internal	P	The chemical reactions and pathways resulting in the formation of internal peptidyl-1-thioglycine, which has an internal C=S bond, instead of an internal C=O bond, in the peptide.
19921	peptidyl-1-thioglycine biosynthetic process, carboxy-terminal	P	The chemical reactions and pathways resulting in the formation of carboxy-terminal peptidyl-1-thioglycine, which has a carboxy-terminal thiocarboxy-C(=O)-SH bond.
19922	protein-chromophore linkage via peptidyl-cysteine	P	The covalent linking of a chromophore to a protein via peptidyl-cysteines.
19923	alpha-1-microglobulin-chromophore linkage	P	The covalent linking of the alpha-1-microglobulin chromophore to the protein; the structure of the chromophore is not known. It is probably heterogeneous and involving two cysteines in thioether bonds.
19926	peptidyl-tryptophan oxidation to tryptophyl quinone	P	The oxidation of peptidyl-tryptophan to form tryptophan-6,7-dione, otherwise known as tryptophyl quinone, which is further modified by cross-linking to either tryptophan or cysteine.
19927	peptide cross-linking via 4'-(S-L-cysteinyl)-L-tryptophyl quinone	P	The cross-linking of a cysteine residue to tryptophyl quinone to form 4'-(S-L-cysteinyl)-L-tryptophyl quinone, a cofactor found at the active site of amine dehydrogenase.
19928	peptide cross-linking via 3-(S-L-cysteinyl)-L-aspartic acid	P	The cross-linking of a cysteine residue to an aspartic acid residue to form 3-(S-L-cysteinyl)-L-aspartic acid.
19929	peptide cross-linking via 4-(S-L-cysteinyl)-L-glutamic acid	P	The cross-linking of a cysteine residue to a glutamic acid residue to form 4-(S-L-cysteinyl)-L-glutamic acid.
19930	cis-14-hydroxy-10,13-dioxo-7-heptadecenoic acid peptidyl-aspartate ester biosynthetic process from peptidyl-aspartic acid	P	The modification of peptidyl-aspartic acid to form peptidyl-cis-14-hydroxy-10,13-dioxo-7-heptadecenoic acid aspartate ester, typical of the barley lipid transfer protein 1.
19931	protein-chromophore linkage via peptidyl-N6-3-dehydroretinal-L-lysine	P	The modification of peptidyl-lysine to form N6-3,4-didehydroretinylidene-L-lysine.
19932	second-messenger-mediated signaling	P	Any intracellular signal transduction in which the signal is passed on within the cell via a second messenger; a small molecule or ion that can be quickly generated or released from intracellular stores, and can diffuse within the cell. Second-messenger signaling includes production or release of the second messenger, and effectors downstream of the second messenger that further transmit the signal within the cell.
19933	cAMP-mediated signaling	P	Any intracellular signal transduction in which the signal is passed on within the cell via cyclic AMP (cAMP). Includes production of cAMP, and downstream effectors that further transmit the signal within the cell.
19934	cGMP-mediated signaling	P	Any intracellular signal transduction in which the signal is passed on within the cell via cyclic GMP (cGMP). Includes production of cGMP, and downstream effectors that further transmit the signal within the cell.
19935	cyclic-nucleotide-mediated signaling	P	Any intracellular signal transduction in which the signal is passed on within the cell via a cyclic nucleotide. Includes production or release of the cyclic nucleotide, and downstream effectors that further transmit the signal within the cell.
19937	protein catenane formation via N6-(L-isoaspartyl)-L-lysine, autocatalytic	P	The autocatalytic formation of isopeptide bonds by ligation of peptidyl-lysine and peptidyl-asparagine residues; known to occur in the capsid of some bacteriophage, such as HK97, where it is thought to provide a mechanism for stabilizing the capsid.
19938	peptide cross-linking via N6-(L-isoaspartyl)-L-lysine, presumed catalytic	P	The formation of isopeptide bonds by ligation of peptidyl-lysine and peptidyl-asparagine residues; occurs in mammals in proteins as yet unidentified by a mechanism probably analogous to that of transglutaminase reactions.
19939	peptidyl-S-palmitoleyl-L-cysteine biosynthetic process from peptidyl-cysteine	P	The modification of peptidyl-cysteine to form peptidyl-S-palmitoleyl-L-cysteine specifically.
19941	modification-dependent protein catabolic process	P	The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent modification of the target protein.
19948	SUMO activating enzyme activity	F	Catalysis of the activation of the proteolytically processed small ubiquitin-related modifier SUMO, through the formation of an ATP-dependent high-energy thiolester bond.
19950	SMT3-dependent protein catabolic process	P	The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by covalent attachment of the ubiquitin-like protein SMT3 to the target protein.
19951	Smt3-protein conjugation	P	The covalent addition to a protein of Smt3, a ubiquitin-like protein.
19953	sexual reproduction	P	A reproduction process that creates a new organism by combining the genetic material of two organisms. It occurs both in eukaryotes and prokaryotes: in multicellular eukaryotic organisms, an individual is created anew; in prokaryotes, the initial cell has additional or transformed genetic material. In a process called genetic recombination, genetic material (DNA) originating from two different individuals (parents) join up so that homologous sequences are aligned with each other, and this is followed by exchange of genetic information. After the new recombinant chromosome is formed, it is passed on to progeny.
19954	asexual reproduction	P	The biological process in which new individuals are produced by either a single cell or a group of cells, in the absence of any sexual process.
19955	cytokine binding	F	Interacting selectively and non-covalently with a cytokine, any of a group of proteins that function to control the survival, growth and differentiation of tissues and cells, and which have autocrine and paracrine activity.
19956	chemokine binding	F	Interacting selectively and non-covalently with a chemokine. Chemokines are a family of small chemotactic cytokines; their name is derived from their ability to induce directed chemotaxis in nearby responsive cells. All chemokines possess a number of conserved cysteine residues involved in intramolecular disulfide bond formation. Some chemokines are considered pro-inflammatory and can be induced during an immune response to recruit cells of the immune system to a site of infection, while others are considered homeostatic and are involved in controlling the migration of cells during normal processes of tissue maintenance or development. Chemokines are found in all vertebrates, some viruses and some bacteria.
19957	C-C chemokine binding	F	Interacting selectively and non-covalently with a C-C chemokine; C-C chemokines do not have an amino acid between the first two cysteines of the characteristic four-cysteine motif.
19958	C-X-C chemokine binding	F	Interacting selectively and non-covalently with a C-X-C chemokine; C-X-C chemokines have a single amino acid between the first two cysteines of the characteristic four cysteine motif.
19959	interleukin-8 binding	F	Interacting selectively and non-covalently with interleukin-8.
19960	C-X3-C chemokine binding	F	Interacting selectively and non-covalently with a C-X3-C chemokine; C-X3-C chemokines have three amino acids between the first two cysteines of the characteristic four-cysteine motif.
19961	interferon binding	F	Interacting selectively and non-covalently with an interferon, a protein produced by the immune systems of many animals in response to a challenge by a foreign agent.
19962	type I interferon binding	F	Interacting selectively and non-covalently with a type I interferon. Type I interferons include the interferon-alpha, beta, delta, epsilon, zeta, kappa, tau, and omega gene families.
19964	interferon-gamma binding	F	Interacting selectively and non-covalently with interferon-gamma. Interferon gamma is the only member of the type II interferon found so far.
19966	interleukin-1 binding	F	Interacting selectively and non-covalently with interleukin-1.
19969	interleukin-10 binding	F	Interacting selectively and non-covalently with interleukin-10.
19970	interleukin-11 binding	F	Interacting selectively and non-covalently with interleukin-11.
19972	interleukin-12 binding	F	Interacting selectively and non-covalently with interleukin-12.
19973	interleukin-13 binding	F	Interacting selectively and non-covalently with interleukin-13.
19974	interleukin-14 binding	F	Interacting selectively and non-covalently with interleukin-14.
19975	interleukin-17 binding	F	Interacting selectively and non-covalently with any member of the interleukin-17 family of cytokines.
19976	interleukin-2 binding	F	Interacting selectively and non-covalently with interleukin-2.
19977	interleukin-21 binding	F	Interacting selectively and non-covalently with interleukin-21.
19978	interleukin-3 binding	F	Interacting selectively and non-covalently with interleukin-3.
19979	interleukin-4 binding	F	Interacting selectively and non-covalently with interleukin-4.
19980	interleukin-5 binding	F	Interacting selectively and non-covalently with interleukin-5.
19981	interleukin-6 binding	F	Interacting selectively and non-covalently with interleukin-6.
19982	interleukin-7 binding	F	Interacting selectively and non-covalently with interleukin-7.
19983	interleukin-9 binding	F	Interacting selectively and non-covalently with interleukin-9.
19985	translesion synthesis	P	The replication of damaged DNA by synthesis across a lesion in the template strand; a specialized DNA polymerase or replication complex inserts a defined nucleotide across from the lesion which allows DNA synthesis to continue beyond the lesion. This process can be mutagenic depending on the damaged nucleotide and the inserted nucleotide.
19988	charged-tRNA amino acid modification	P	The covalent alteration of an amino acid charged on a tRNA before it is incorporated into a protein, as in N-formylmethionine, selenocysteine or pyrrolysine.
19990	pteridine catabolic process	P	The chemical reactions and pathways resulting in the breakdown of pteridine, pyrazino(2,3-dipyrimidine), the parent structure of pterins and the pteroyl group.
19991	septate junction assembly	P	The assembly of a septate junction, an intercellular junction found in invertebrate epithelia that is characterized by a ladder like appearance in electron micrographs and thought to provide structural strength and to provide a barrier to diffusion of solutes through the intercellular space.
19992	diacylglycerol binding	F	Interacting selectively and non-covalently with diacylglycerol, a diester of glycerol and two fatty acids.
20002	host cell plasma membrane	C	The plasma membrane surrounding a host cell.
20003	symbiont-containing vacuole	C	Membrane-bounded vacuole within a host cell in which a symbiont organism resides. The vacuole membrane is derived from both the host and symbiont.
20004	symbiont-containing vacuolar space	C	The space between a symbiont plasma membrane and the symbiont-containing vacuole membrane.
20005	symbiont-containing vacuole membrane	C	The lipid bilayer surrounding a symbiont-containing vacuole, derived from both the host and symbiont.
20006	symbiont-containing vacuolar membrane network	C	Tubular network of extensions from the symbiont-containing vacuole membrane that protrude into the host cytoplasm.
20007	apical complex	C	A group of cytoskeletal structures and associated membrane-bounded organelles found at the anterior end of adult obligate intracellular protozoan parasites in the phylum Apicomplexa. The apical complex is involved in attachment to and penetration of the host cell, and in parasite proliferation.
20008	rhoptry	C	A large, club-shaped secretory organelle that forms part of the apical complex of an apicomplexan parasite, and consists of a bulbous body and a narrow electron-dense neck that extends through the conoid at the apical tip of the parasite. The rhoptry necks serve as ducts through which the contents of the rhoptries are secreted after attachment to the host has been completed and at the commencement of invasion. Rhoptry proteins function in the biogenesis and host organellar association of the parasitophorous vacuole.
20009	microneme	C	A small, elongated secretory organelle that forms part of the apical complex, located along the main axis of an apicomplexan parasite cell within the extreme apical region and at the periphery under the inner membrane complex. Of the specialized secretory compartments identified in apicomplexans, micronemes discharge their contents first, during initial contact of the parasite's apical pole with the host cell surface. Micronemal proteins function during parasite attachment and penetration into the target cell.
20010	conoid	C	A spiral cytoskeletal structure located at the apical end of the apical complex in some apicomplexan parasites. Fibers form a left-handed spiral, and are comprised of tubulin protofilaments organized in a ribbon-like structure that differs from the conventional tubular structure characteristic of microtubules.
20011	apicoplast	C	The plastid organelle found in apicomplexans.
20012	evasion or tolerance of host immune response	P	Any process, either active or passive, by which an organism avoids the effects of the host organism's immune response. The host is defined as the larger of the organisms involved in a symbiotic interaction.
20013	modulation by symbiont of host erythrocyte aggregation	P	Any process in which a symbiont organism modulates the frequency, rate or extent of erythrocyte aggregation in its host organism, e.g. the binding of parasite-infected erythrocytes to uninfected erythrocytes.
20014	schizogony	P	Cell division by multiple fission in which nuclei and other organelles in the parent cell divide repeatedly and move to the cell periphery before internal membranes develop around them, producing a large number of daughter cells simultaneously.
20015	glycosome	C	A membrane-bounded organelle found in organisms from the order Kinetoplastida that houses the enzymes of glycolysis.
20016	ciliary pocket	C	Invagination of the plasma membrane from which a cilium (also called flagellum) protrudes.
20018	ciliary pocket membrane	C	That part of the plasma membrane found in the ciliary pocket (also called flagellar pocket).
20020	food vacuole	C	Vacuole within a parasite used for digestion of the host cell cytoplasm. An example of this component is found in the Apicomplexa.
20021	immortalization of host cell	P	The modification of a host cell into an immortal cell line as a consequence of infection. The host is defined as the larger of the organisms involved in a symbiotic interaction.
20022	acidocalcisome	C	An electron-dense acidic membrane-bounded organelle which contains a matrix of pyrophosphate and polyphosphates with bound calcium and other cations.
20023	kinetoplast	C	A sub-structure within the large single mitochondrion of kinetoplastid parasites and which is closely associated with the flagellar pocket and basal body of the flagellum.
20025	subpellicular microtubule	C	Singlet microtubules that lie underneath the inner membrane complex and emanate from the basal ring of the conoid.
20026	merozoite dense granule	C	Electron-dense organelle with a granular internal matrix found throughout the merozoite life cycle stage of apicomplexan parasites; contains proteins destined to be secreted into the parasitophorous vacuole following parasite invasion of a host cell.
20027	hemoglobin metabolic process	P	The chemical reactions and pathways involving hemoglobin, including its uptake and utilization.
20028	hemoglobin import	P	The directed movement into a tissue, cell or organelle of externally available hemoglobin.
20030	infected host cell surface knob	C	Protrusion that develops in the plasma membrane of a parasitized erythrocyte. An example of this component is found in Plasmodium species.
20031	polar ring of apical complex	C	An electron dense ring at the most anterior position of the apical complex, from which the conoid fibers originate; formed during an invasive life cycle stage of an apicomplexan parasite.
20032	basal ring of apical complex	C	An electron dense ring at the most posterior position of the apical complex, from which the subpellicular microtubules originate; formed during an invasive life cycle stage of an apicomplexan parasite.
20033	antigenic variation	P	Any process involved in the biological strategy of changing antigenic determinants on the surface that are exposed to another organism's immune system.
20035	cytoadherence to microvasculature, mediated by symbiont protein	P	The adherence of symbiont-infected erythrocytes to microvascular endothelium via symbiont proteins embedded in the membrane of the erythrocyte.
20036	Maurer's cleft	C	A disk-like structure that appears at the periphery of a red blood cell infected by an apicomplexan parasite, characterized by a translucent lumen and an electron-dense coat of variable thickness; often appears to be tethered to the host cell membrane by fibrous connections with the erythrocyte cytoskeleton.
20037	heme binding	F	Interacting selectively and non-covalently with heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring.
20038	subpellicular network	C	A mechanically stable cytoskeletal structure associated with the cytoplasmic face of the pellicle and surrounding the microtubule-based cytoskeleton.
20039	pellicle	C	The structure enclosing an apicomplexan parasite cell; consists of the cell membrane with its associated infrastructure of microtubules, microfilaments and other organelles.
21501	prechordal plate formation	P	The formation of the prechordal plate. The prechordal plate is a thickening of the endoderm at the cranial end of the primitive streak formed by the involution of Spemann's organizer cells. The prechordal plate and the notochord induce the formation of the neural plate from the overlying ectodermal cells.
21502	neural fold elevation formation	P	The process in which the lateral borders of the neural plate begin to migrate upwards to form the neural folds, caused by the proliferation of the underlying mesoderm.
21503	neural fold bending	P	The morphogenesis of the neural fold elevations that results in the movement of the tips of the elevations towards each other in order to fuse.
21504	neural fold hinge point formation	P	The formation of the median and lateral hinge points in the neural folds. These are created by apical constriction and basal expansion of the underlying neural cells. The median hinge point extends for the entire length of the neural tube, and the lateral hinge points do not form in the spinal cord region of the neural tube.
21505	neural fold folding	P	The process of folding the neuroepithelium around the medial hinge point to create the neural elevations, and around the lateral hinge points to produce convergence of the folds.
21506	anterior neuropore closure	P	The joining together of the neural folds of the rostral opening of the neural tube. The anterior neuropore appears before the process of neural tube closure is complete.
21507	posterior neuropore closure	P	The joining together of the neural folds of the caudal opening of the neural tube. The posterior neuropore appears before the process of neural tube closure is complete.
21508	floor plate formation	P	The formation of a ventral region of glial cells in the neural tube that provides inductive signals for the specification of neuronal cell types. The floor plate is evident at the ventral midline by the neural fold stage.
21509	roof plate formation	P	The formation of a single row of glia at the dorsal midline of the developing neural tube. This region provides inductive signals for the specification of neuronal cell types and of the specification of neural crest cells. The cells comprising the roof plate are the precursors to radial glial cells.
21510	spinal cord development	P	The process whose specific outcome is the progression of the spinal cord over time, from its formation to the mature structure. The spinal cord primarily conducts sensory and motor nerve impulses between the brain and the peripheral nervous tissues.
21511	spinal cord patterning	P	The regionalization process that regulates the coordinated growth and establishes the non-random spatial arrangement of the spinal cord.
21512	spinal cord anterior/posterior patterning	P	The process that regulates the coordinated growth and differentiation that establishes the non-random anterior-posterior spatial arrangement of the spinal cord.
21513	spinal cord dorsal/ventral patterning	P	The process that regulates the coordinated growth and differentiation that establishes the non-random dorsal-ventral spatial arrangement of the spinal cord.
21514	ventral spinal cord interneuron differentiation	P	The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of ventral spinal cord interneurons. Ventral spinal cord interneurons are cells located in the ventral portion of the spinal cord that transmit signals between sensory and motor neurons and are required for reflexive responses. Differentiation includes the processes involved in commitment of a cell to a specific fate.
21515	cell differentiation in spinal cord	P	The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the spinal cord. Differentiation includes the processes involved in commitment of a cell to a specific fate.
21516	dorsal spinal cord development	P	The process whose specific outcome is the progression of the dorsal region of the spinal cord over time, from its formation to the mature structure. The dorsal region of the mature spinal cord contains neurons that process and relay sensory input.
21517	ventral spinal cord development	P	The process whose specific outcome is the progression of the ventral region of the spinal cord over time, from its formation to the mature structure. The neurons of the ventral region of the mature spinal cord participate in motor output.
21518	spinal cord commissural neuron specification	P	The process in which a cell becomes capable of differentiating autonomously into a commissural neuron in an environment that is neutral with respect to the developmental pathway.
21519	spinal cord association neuron specification	P	The process in which a cell becomes capable of differentiating autonomously into an association neuron in an environment that is neutral with respect to the developmental pathway.
21520	spinal cord motor neuron cell fate specification	P	The process in which a cell becomes capable of differentiating autonomously into a motor neuron in an environment that is neutral with respect to the developmental pathway.
21521	ventral spinal cord interneuron specification	P	The process in which a cell becomes capable of differentiating autonomously into a ventral spinal cord interneuron in an environment that is neutral with respect to the developmental pathway.
21522	spinal cord motor neuron differentiation	P	The process in which neuroepithelial cells in the ventral neural tube acquire specialized structural and/or functional features of motor neurons. Motor neurons innervate an effector (muscle or glandular) tissue and are responsible for transmission of motor impulses from the brain to the periphery. Differentiation includes the processes involved in commitment of a cell to a specific fate.
21523	somatic motor neuron differentiation	P	The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of somatic motor neurons. Somatic motor neurons innervate skeletal muscle targets and are responsible for transmission of motor impulses from the brain to the periphery. Differentiation includes the processes involved in commitment of a cell to a specific fate.
21524	visceral motor neuron differentiation	P	The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of visceral motor neurons. Visceral motor neurons innervate glandular targets and are responsible for transmission of motor impulses from the brain to the periphery. Differentiation includes the processes involved in commitment of a cell to a specific fate.
21525	lateral motor column neuron differentiation	P	The process in which differentiating motor neurons in the neural tube acquire the specialized structural and/or functional features of lateral motor column neurons. Lateral motor column neurons are generated only on limb levels and send axons into the limb mesenchyme. Differentiation includes the processes involved in commitment of a cell to a specific fate.
21526	medial motor column neuron differentiation	P	The process in which differentiating motor neurons in the neural tube acquire the specialized structural and/or functional features of medial motor column neurons. Medial motor column neurons are generated at all rostrocaudal levels and send axons to the axial muscles (medial group) and to the body wall muscles (lateral group). Differentiation includes the processes involved in commitment of a cell to a specific fate.
21527	spinal cord association neuron differentiation	P	The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of association neurons. Association neurons are cells located in the dorsal portion of the spinal cord that integrate sensory input. Differentiation includes the processes involved in commitment of a cell to a specific fate.
21528	commissural neuron differentiation in spinal cord	P	The process in which neuroepithelial cells in the ventral neural tube acquire specialized structural and/or functional features of commissural neurons. Commissural neurons in both vertebrates and invertebrates transfer information from one side of their bodies to the other through the midline. Differentiation includes the processes involved in commitment of a cell to a specific fate.
21529	spinal cord oligodendrocyte cell differentiation	P	The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of oligodendrocytes. Oligodendrocytes are non-neuronal cells. The primary function of oligodendrocytes is the myelination of nerve axons in the central nervous system. Differentiation includes the processes involved in commitment of a cell to a specific fate.
21530	spinal cord oligodendrocyte cell fate specification	P	The process in which a cell becomes capable of differentiating autonomously into an oligodendrocyte in an environment that is neutral with respect to the developmental pathway.
21531	spinal cord radial glial cell differentiation	P	The process in which neuroepithelial cells in the ventral neural tube acquire specialized structural and/or functional features of radial glial cells. Radial cell precursors differentiate into both neuronal cell types and mature radial glial cells. Mature radial glial cells regulate the axon growth and pathfinding processes that occur during white matter patterning of the developing spinal cord. Differentiation includes the processes involved in commitment of a cell to a specific fate.
21532	neural tube patterning	P	The regionalization process that regulates the coordinated growth that establishes the non-random spatial arrangement of the neural tube.
21533	cell differentiation in hindbrain	P	The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mature cells of the hindbrain. Differentiation includes the processes involved in commitment of a cell to a specific fate.
21534	cell proliferation in hindbrain	P	The multiplication or reproduction of cells, resulting in the expansion of a cell population in the hindbrain.
21535	cell migration in hindbrain	P	The orderly movement of a cell that will reside in the hindbrain.
21536	diencephalon development	P	The process whose specific outcome is the progression of the diencephalon over time, from its formation to the mature structure. The diencephalon is the paired caudal parts of the prosencephalon from which the thalamus, hypothalamus, epithalamus and subthalamus are derived; these regions regulate autonomic, visceral and endocrine function, and process information directed to the cerebral cortex.
21537	telencephalon development	P	The process whose specific outcome is the progression of the telencephalon over time, from its formation to the mature structure. The telencephalon is the paired anteriolateral division of the prosencephalon plus the lamina terminalis from which the olfactory lobes, cerebral cortex, and subcortical nuclei are derived.
21538	epithalamus development	P	The progression of the epithalamus over time from its initial formation until its mature state. The epithalamus is the small dorsomedial area of the thalamus including the habenular nuclei and associated fiber bundles, the pineal body, and the epithelial roof of the third ventricle.
21539	subthalamus development	P	The process whose specific outcome is the progression of the subthalamus over time, from its formation to the mature structure. The subthalamus is the anterior part of the diencephalon that lies between the thalamus, hypothalamus, and tegmentum of the mesencephalon, including subthalamic nucleus, zona incerta, the fields of Forel, and the nucleus of ansa lenticularis.
21540	corpus callosum morphogenesis	P	The process in which the anatomical structures of the corpus callosum are generated and organized. The corpus callosum is a thick bundle of nerve fibers comprising a commissural plate connecting the two cerebral hemispheres. It consists of contralateral axon projections that provides communications between the right and left cerebral hemispheres.
21541	ammon gyrus development	P	The process whose specific outcome is the progression of the ammon gyrus over time, from its formation to the mature structure. The ammon gyrus, often subdivided into the CA1 and CA3 regions, is one of the two interlocking gyri of the hippocampus that is rich in large pyramidal neurons.
21542	dentate gyrus development	P	The process whose specific outcome is the progression of the dentate gyrus over time, from its formation to the mature structure. The dentate gyrus is one of two interlocking gyri of the hippocampus. It contains granule cells, which project to the pyramidal cells and interneurons of the CA3 region of the ammon gyrus.
21543	pallium development	P	The process whose specific outcome is the progression of the pallium over time, from its formation to the mature structure. The pallium is the roof region of the telencephalon.
21544	subpallium development	P	The process whose specific outcome is the progression of the subpallium over time, from its formation to the mature structure. The subpallium is the base region of the telencephalon.
21545	cranial nerve development	P	The process whose specific outcome is the progression of the cranial nerves over time, from its formation to the mature structure. The cranial nerves are composed of twelve pairs of nerves that emanate from the nervous tissue of the hindbrain. These nerves are sensory, motor, or mixed in nature, and provide the motor and general sensory innervation of the head, neck and viscera. They mediate vision, hearing, olfaction and taste and carry the parasympathetic innervation of the autonomic ganglia that control visceral functions.
21546	rhombomere development	P	The process whose specific outcome is the progression of the rhombomere over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates.
21547	midbrain-hindbrain boundary initiation	P	The regionalization process that gives rise to the midbrain-hindbrain boundary. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. An organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate.
21548	pons development	P	The process whose specific outcome is the progression of the pons over time, from its formation to the mature structure. The pons lies above the medulla and next to the cerebellum. The pons conveys information about movement from the cerebral hemisphere to the cerebellum.
21549	cerebellum development	P	The process whose specific outcome is the progression of the cerebellum over time, from its formation to the mature structure. The cerebellum is the portion of the brain in the back of the head between the cerebrum and the pons. In mice, the cerebellum controls balance for walking and standing, modulates the force and range of movement and is involved in the learning of motor skills.
21550	medulla oblongata development	P	The process whose specific outcome is the progression of the medulla oblongata over time, from its formation to the mature structure. The medulla oblongata lies directly above the spinal cord and controls vital autonomic functions such as digestion, breathing and the control of heart rate.
21551	central nervous system morphogenesis	P	The process in which the anatomical structure of the central nervous system is generated and organized. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain and spinal cord. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord.
21552	midbrain-hindbrain boundary structural organization	P	The process that contributes to the act of creating the structural organization of the midbrain-hindbrain boundary structure. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. An organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate.
21553	olfactory nerve development	P	The process whose specific outcome is the progression of the olfactory nerve over time, from its formation to the mature structure. The olfactory nerve is a collection of sensory nerve rootlets that extend down from the olfactory bulb to the olfactory mucosa of the upper parts of the nasal cavity. This nerve conducts odor information to the brainstem.
21554	optic nerve development	P	The process whose specific outcome is the progression of the optic nerve over time, from its formation to the mature structure. The sensory optic nerve originates from the bipolar cells of the retina and conducts visual information to the brainstem. The optic nerve exits the back of the eye in the orbit, enters the optic canal, and enters the central nervous system at the optic chiasm (crossing) where the nerve fibers become the optic tract just prior to entering the hindbrain.
21555	midbrain-hindbrain boundary morphogenesis	P	The process in which the anatomical structure of the midbrain-hindbrain boundary is generated and organized. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. An organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate.
21556	central nervous system formation	P	The process that gives rise to the central nervous system. This process pertains to the initial formation of a structure from unspecified parts. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain, spinal cord and spinal nerves. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord.
21557	oculomotor nerve development	P	The process whose specific outcome is the progression of the oculomotor nerve over time, from its formation to the mature structure. This motor nerve innervates all extraocular muscles except the superior oblique and the lateral rectus muscles. The superior division supplies the levator palpebrae superioris and superior rectus muscles. The inferior division supplies the medial rectus, inferior rectus and inferior oblique muscles. This nerve also innervates the striated muscles of the eyelid. Pupillary constriction and lens movement are mediated by this nerve for near vision. In the orbit the inferior division sends branches that enter the ciliary ganglion where they form functional contacts (synapses) with the ganglion cells. The ganglion cells send nerve fibers into the back of the eye where they travel to ultimately innervate the ciliary muscle and the constrictor pupillae muscle.
21558	trochlear nerve development	P	The process whose specific outcome is the progression of the trochlear nerve over time, from its formation to the mature structure. The trochlear nerve is a motor nerve and is the only cranial nerve to exit the brain dorsally. The trochlear nerve innervates the superior oblique muscle.
21559	trigeminal nerve development	P	The process whose specific outcome is the progression of the trigeminal nerve over time, from its formation to the mature structure. The trigeminal nerve is composed of three large branches. They are the ophthalmic (V1, sensory), maxillary (V2, sensory) and mandibular (V3, motor and sensory) branches. The sensory ophthalmic branch travels through the superior orbital fissure and passes through the orbit to reach the skin of the forehead and top of the head. The maxillary nerve contains sensory branches that reach the pterygopalatine fossa via the inferior orbital fissure (face, cheek and upper teeth) and pterygopalatine canal (soft and hard palate, nasal cavity and pharynx). The motor part of the mandibular branch is distributed to the muscles of mastication, the mylohyoid muscle and the anterior belly of the digastric. The mandibular nerve also innervates the tensor veli palatini and tensor tympani muscles. The sensory part of the mandibular nerve is composed of branches that carry general sensory information from the mucous membranes of the mouth and cheek, anterior two-thirds of the tongue, lower teeth, skin of the lower jaw, side of the head and scalp and meninges of the anterior and middle cranial fossae.
21560	abducens nerve development	P	The process whose specific outcome is the progression of the abducens nerve over time, from its formation to the mature structure. The motor function of the abducens nerve is to contract the lateral rectus which results in abduction of the eye.
21561	facial nerve development	P	The process whose specific outcome is the progression of the facial nerve over time, from its formation to the mature structure. This sensory and motor nerve supplies the muscles of facial expression and the expression and taste at the anterior two-thirds of the tongue. The principal branches are the superficial opthalmic, buccal, palatine and hyomandibular. The main trunk synapses within pterygopalatine ganglion in the parotid gland and this ganglion then gives off nerve branches which supply the lacrimal gland and the mucous secreting glands of the nasal and oral cavities.
21562	vestibulocochlear nerve development	P	The process whose specific outcome is the progression of the vestibulocochlear nerve over time, from its formation to the mature structure. This sensory nerve innervates the membranous labyrinth of the inner ear. The vestibular branch innervates the vestibular apparatus that senses head position changes relative to gravity. The auditory branch innervates the cochlear duct, which is connected to the three bony ossicles which transduce sound waves into fluid movement in the cochlea.
21563	glossopharyngeal nerve development	P	Various sensory and motor branches of the glossopharyngeal nerve supply nerve connections to the pharynx and back of the tongue. The branchial motor component contains motor fibers that innervate muscles that elevate the pharynx and larynx, and the tympanic branch supplies parasympathetic fibers to the otic ganglion.
21564	vagus nerve development	P	The process whose specific outcome is the progression of the vagus nerve over time, from its formation to the mature structure. This nerve is primarily sensory but also has visceromotor components. It originates in the brain stem and controls many autonomic functions of the heart, lungs, stomach, pharynx, larynx, trachea, esophagus and other gastrointestinal tract components. It controls some motor functions such as speech. The sensory branches mediate sensation from the pharynx, larynx, thorax and abdomen; it also innervates taste buds in the epiglottis.
21565	accessory nerve development	P	The process whose specific outcome is the progression of the accessory nerve over time, from its formation to the mature structure. In mice, the spinal branch of this motor nerve innervates the trapezius and the sternocleidomastoid muscles. The cranial branch joins the vagus nerve and innervates the same targets as the vagus nerve.
21566	hypoglossal nerve development	P	The process whose specific outcome is the progression of the hypoglossal nerve over time, from its formation to the mature structure. This motor nerve innervates all the intrinsic and all but one of the extrinsic muscles of the tongue.
21567	rhombomere 1 development	P	The process whose specific outcome is the progression of rhombomere 1 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.
21568	rhombomere 2 development	P	The process whose specific outcome is the progression of rhombomere 2 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.
21569	rhombomere 3 development	P	The process whose specific outcome is the progression of rhombomere 3 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.
21570	rhombomere 4 development	P	The process whose specific outcome is the progression of rhombomere 4 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.
21571	rhombomere 5 development	P	The process whose specific outcome is the progression of rhombomere 5 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.
21572	rhombomere 6 development	P	The process whose specific outcome is the progression of rhombomere 6 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.
21573	rhombomere 7 development	P	The process whose specific outcome is the progression of rhombomere 7 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.
21574	rhombomere 8 development	P	The process whose specific outcome is the progression of rhombomere 8 over time, from its formation to the mature structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.
21575	hindbrain morphogenesis	P	The process in which the anatomical structure of the hindbrain is generated and organized. The hindbrain is the region consisting of the medulla, pons and cerebellum. Areas of the hindbrain control motor and autonomic functions.
21576	hindbrain formation	P	The process that gives rise to the hindbrain. This process pertains to the initial formation of a structure from unspecified parts. The hindbrain is the region consisting of the medulla, pons and cerebellum. Areas of the hindbrain control motor and autonomic functions.
21577	hindbrain structural organization	P	The process that contributes to the act of creating the structural organization of the hindbrain. This process pertains to the physical shaping of a rudimentary structure. The hindbrain is the region consisting of the medulla, pons and cerebellum. Areas of the hindbrain control motor and autonomic functions.
21578	hindbrain maturation	P	A developmental process, independent of morphogenetic (shape) change, that is required for the hindbrain to attain its fully functional state. The hindbrain is the region consisting of the medulla, pons and cerebellum. Areas of the hindbrain control motor and autonomic functions.
21579	medulla oblongata morphogenesis	P	The process in which the anatomical structure of the medulla oblongata is generated and organized. The medulla oblongata lies directly above the spinal cord and controls vital autonomic functions such as digestion, breathing and the control of heart rate.
21580	medulla oblongata formation	P	The process that gives rise to the medulla oblongata. This process pertains to the initial formation of a structure from unspecified parts. The medulla oblongata lies directly above the spinal cord and controls vital autonomic functions such as digestion, breathing and the control of heart rate.
21581	medulla oblongata structural organization	P	The process that contributes to the act of creating the structural organization of the medulla oblongata. This process pertains to the physical shaping of a rudimentary structure. The medulla oblongata lies directly above the spinal cord and controls vital autonomic functions such as digestion, breathing and the control of heart rate.
21582	medulla oblongata maturation	P	A developmental process, independent of morphogenetic (shape) change, that is required for the medulla oblongata to attain its fully functional state. The medulla oblongata lies directly above the spinal cord and controls vital autonomic functions such as digestion, breathing and the control of heart rate.
21583	pons morphogenesis	P	The process in which the anatomical structure of the pons is generated and organized. The pons lies above the medulla and next to the cerebellum. The pons conveys information about movement from the cerebral hemisphere to the cerebellum.
21584	pons formation	P	The process that gives rise to the pons. This process pertains to the initial formation of a structure from unspecified parts. The pons lies above the medulla and next to the cerebellum. The pons conveys information about movement from the cerebral hemisphere to the cerebellum.
21585	pons structural organization	P	The process that contributes to the act of creating the structural organization of the pons. This process pertains to the physical shaping of a rudimentary structure. The pons lies above the medulla and next to the cerebellum. The pons conveys information about movement from the cerebral hemisphere to the cerebellum.
21586	pons maturation	P	A developmental process, independent of morphogenetic (shape) change, that is required for the pons to attain its fully functional state. The pons lies above the medulla and next to the cerebellum. The pons conveys information about movement from the cerebral hemisphere to the cerebellum.
21587	cerebellum morphogenesis	P	The process in which the anatomical structure of the cerebellum is generated and organized. The cerebellum is the portion of the brain in the back of the head between the cerebrum and the pons. The cerebellum controls balance for walking and standing, modulates the force and range of movement and is involved in the learning of motor skills.
21588	cerebellum formation	P	The process that gives rise to the cerebellum. This process pertains to the initial formation of a structure from unspecified parts. The cerebellum is the portion of the brain in the back of the head between the cerebrum and the pons. The cerebellum controls balance for walking and standing, modulates the force and range of movement and is involved in the learning of motor skills.
21589	cerebellum structural organization	P	The process that contributes to the act of creating the structural organization of the cerebellum. This process pertains to the physical shaping of a rudimentary structure. The cerebellum is the portion of the brain in the back of the head between the cerebrum and the pons. The cerebellum controls balance for walking and standing, modulates the force and range of movement and is involved in the learning of motor skills.
21590	cerebellum maturation	P	A developmental process, independent of morphogenetic (shape) change, that is required for the cerebellum to attain its fully functional state. The cerebellum is the portion of the brain in the back of the head between the cerebrum and the pons. The cerebellum controls balance for walking and standing, modulates the force and range of movement and is involved in the learning of motor skills.
21591	ventricular system development	P	The process whose specific outcome is the progression of the brain ventricular system over time, from its formation to the mature structure. The brain ventricular system consists of four communicating cavities within the brain that are continuous with the central canal of the spinal cord. These cavities include two lateral ventricles, the third ventricle and the fourth ventricle. Cerebrospinal fluid fills the ventricles and is produced by the choroid plexus.
21592	fourth ventricle development	P	The process whose specific outcome is the progression of the fourth ventricle over time, from its formation to the mature structure. The fourth ventricle is an irregularly shaped cavity in the rhombencephalon, between the medulla oblongata, the pons, and the isthmus in front, and the cerebellum behind. It is continuous with the central canal of the cord below and with the cerebral aqueduct above, and through its lateral and median apertures it communicates with the subarachnoid space.
21593	rhombomere morphogenesis	P	The process in which the anatomical structure of the rhombomere is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates.
21594	rhombomere formation	P	The process that gives rise to the rhombomere. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates.
21595	rhombomere structural organization	P	The process that contributes to the act of creating the structural organization of the rhombomere structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates.
21597	central nervous system structural organization	P	The process that contributes to the act of creating the structural organization of the central nervous system structure. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain, spinal cord and spinal nerves. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord.
21598	abducens nerve morphogenesis	P	The process in which the anatomical structure of the abducens nerve is generated and organized. The motor function of the abducens nerve is to contract the lateral rectus which results in abduction of the eye.
21599	abducens nerve formation	P	The process that gives rise to the abducens nerve. This process pertains to the initial formation of a structure from unspecified parts. The motor function of the abducens nerve is to contract the lateral rectus which results in abduction of the eye.
21600	abducens nerve structural organization	P	The process that contributes to the act of creating the structural organization of the abducens nerve. This process pertains to the physical shaping of a rudimentary structure. The motor function of the abducens nerve is to contract the lateral rectus which results in abduction of the eye.
21601	abducens nerve maturation	P	A developmental process, independent of morphogenetic (shape) change, that is required for the abducens nerve to attain its fully functional state. The motor function of the abducens nerve is to contract the lateral rectus which results in abduction of the eye.
21602	cranial nerve morphogenesis	P	The process in which the anatomical structure of the cranial nerves are generated and organized. The cranial nerves are composed of twelve pairs of nerves that emanate from the nervous tissue of the hindbrain. These nerves are sensory, motor, or mixed in nature, and provide the motor and general sensory innervation of the head, neck and viscera. They mediate vision, hearing, olfaction and taste and carry the parasympathetic innervation of the autonomic ganglia that control visceral functions.
21603	cranial nerve formation	P	The process that gives rise to the cranial nerves. This process pertains to the initial formation of a structure from unspecified parts. The cranial nerves are composed of twelve pairs of nerves that emanate from the nervous tissue of the hindbrain. These nerves are sensory, motor, or mixed in nature, and provide the motor and general sensory innervation of the head, neck and viscera. They mediate vision, hearing, olfaction and taste and carry the parasympathetic innervation of the autonomic ganglia that control visceral functions.
21604	cranial nerve structural organization	P	The process that contributes to the act of creating the structural organization of the cranial nerves. This process pertains to the physical shaping of a rudimentary structure. The cranial nerves are composed of twelve pairs of nerves that emanate from the nervous tissue of the hindbrain. These nerves are sensory, motor, or mixed in nature, and provide the motor and general sensory innervation of the head, neck and viscera. They mediate vision, hearing, olfaction and taste and carry the parasympathetic innervation of the autonomic ganglia that control visceral functions.
21605	cranial nerve maturation	P	A developmental process, independent of morphogenetic (shape) change, that is required for a cranial nerve to attain its fully functional state. The cranial nerves are composed of twelve pairs of nerves that emanate from the nervous tissue of the hindbrain. These nerves are sensory, motor, or mixed in nature, and provide the motor and general sensory innervation of the head, neck and viscera. They mediate vision, hearing, olfaction and taste and carry the parasympathetic innervation of the autonomic ganglia that control visceral functions.
21606	accessory nerve maturation	P	A developmental process, independent of morphogenetic (shape) change, that is required for the accessory nerve to attain its fully functional state. The spinal branch of this motor nerve innervates the trapezius and the sternocleidomastoid muscles. The cranial branch joins the vagus nerve and innervates the same targets as the vagus nerve.
21607	accessory nerve morphogenesis	P	The process in which the anatomical structure of the accessory nerve is generated and organized. The spinal branch of this motor nerve innervates the trapezius and the sternocleidomastoid muscles. The cranial branch joins the vagus nerve and innervates the same targets as the vagus nerve.
21608	accessory nerve formation	P	The process that gives rise to the accessory nerve. This process pertains to the initial formation of a structure from unspecified parts. The spinal branch of this motor nerve innervates the trapezius and the sternocleidomastoid muscles. The cranial branch joins the vagus nerve and innervates the same targets as the vagus nerve.
21609	accessory nerve structural organization	P	The process that contributes to the act of creating the structural organization of the accessory nerve This process pertains to the physical shaping of a rudimentary structure. The spinal branch of this motor nerve innervates the trapezius and the sternocleidomastoid muscles. The cranial branch joins the vagus nerve and innervates the same targets as the vagus nerve.
21610	facial nerve morphogenesis	P	The process in which the anatomical structure of the facial nerve is generated and organized. This sensory and motor nerve supplies the muscles of facial expression and the expression and taste at the anterior two-thirds of the tongue. The principal branches are the superficial opthalmic, buccal, palatine and hyomandibular. The main trunk synapses within pterygopalatine ganglion in the parotid gland and this ganglion then gives of nerve branches which supply the lacrimal gland and the mucous secreting glands of the nasal and oral cavities.
21611	facial nerve formation	P	The process that gives rise to the facial nerve. This process pertains to the initial formation of a structure from unspecified parts. This sensory and motor nerve supplies the muscles of facial expression and the expression and taste at the anterior two-thirds of the tongue. The principal branches are the superficial opthalmic, buccal, palatine and hyomandibular. The main trunk synapses within pterygopalatine ganglion in the parotid gland and this ganglion then gives of nerve branches which supply the lacrimal gland and the mucous secreting glands of the nasal and oral cavities.
21612	facial nerve structural organization	P	The process that contributes to the act of creating the structural organization of the facial nerve. This process pertains to the physical shaping of a rudimentary structure. This sensory and motor nerve supplies the muscles of facial expression and the expression and taste at the anterior two-thirds of the tongue. The principal branches are the superficial opthalmic, buccal, palatine and hyomandibular. The main trunk synapses within pterygopalatine ganglion in the parotid gland and this ganglion then gives of nerve branches which supply the lacrimal gland and the mucous secreting glands of the nasal and oral cavities.
21613	facial nerve maturation	P	A developmental process, independent of morphogenetic (shape) change, that is required for the facial nerve to attain its fully functional state. This sensory and motor nerve supplies the muscles of facial expression and the expression and taste at the anterior two-thirds of the tongue. The principal branches are the superficial opthalmic, buccal, palatine and hyomandibular. The main trunk synapses within pterygopalatine ganglion in the parotid gland and this ganglion then gives of nerve branches which supply the lacrimal gland and the mucous secreting glands of the nasal and oral cavities.
21614	glossopharyngeal nerve maturation	P	A developmental process, independent of morphogenetic (shape) change, that is required for the glossopharyngeal nerve to attain its fully functional state. Various sensory and motor branches of the glossopharyngeal nerve supply nerve connections to the pharynx and back of the tongue. The branchial motor component contains motor fibers that innervate muscles that elevate the pharynx and larynx, and the tympanic branch supplies parasympathetic fibers to the otic ganglion.
21615	glossopharyngeal nerve morphogenesis	P	The process in which the anatomical structure of the glossopharyngeal nerve is generated and organized. Various sensory and motor branches of the glossopharyngeal nerve supply nerve connections to the pharynx and back of the tongue. The branchial motor component contains motor fibers that innervate muscles that elevate the pharynx and larynx, and the tympanic branch supplies parasympathetic fibers to the otic ganglion.
21616	glossopharyngeal nerve formation	P	The process that gives rise to the glossopharyngeal nerve. This process pertains to the initial formation of a structure from unspecified parts. Various sensory and motor branches of the glossopharyngeal nerve supply nerve connections to the pharynx and back of the tongue. The branchial motor component contains motor fibers that innervate muscles that elevate the pharynx and larynx, and the tympanic branch supplies parasympathetic fibers to the otic ganglion.
21617	glossopharyngeal nerve structural organization	P	The process that contributes to the act of creating the structural organization of the glossopharyngeal nerve. This process pertains to the physical shaping of a rudimentary structure. Various sensory and motor branches of the glossopharyngeal nerve supply nerve connections to the pharynx and back of the tongue. The branchial motor component contains motor fibers that innervate muscles that elevate the pharynx and larynx, and the tympanic branch supplies parasympathetic fibers to the otic ganglion.
21618	hypoglossal nerve morphogenesis	P	The process in which the anatomical structure of the hypoglossal nerve is generated and organized. This motor nerve innervates all the intrinsic and all but one of the extrinsic muscles of the tongue.
21619	hypoglossal nerve maturation	P	A developmental process, independent of morphogenetic (shape) change, that is required for the hypoglossal nerve to attain its fully functional state. This motor nerve innervates all the intrinsic and all but one of the extrinsic muscles of the tongue.
21620	hypoglossal nerve formation	P	The process that gives rise to the hypoglossal nerve. This process pertains to the initial formation of a structure from unspecified parts. This motor nerve innervates all the intrinsic and all but one of the extrinsic muscles of the tongue.
21621	hypoglossal nerve structural organization	P	The process that contributes to the act of creating the structural organization of the hypoglossal nerve. This process pertains to the physical shaping of a rudimentary structure. This motor nerve innervates all the intrinsic and all but one of the extrinsic muscles of the tongue.
21622	oculomotor nerve morphogenesis	P	The process in which the anatomical structure of the oculomotor nerve is generated and organized. This motor nerve innervates all extraocular muscles except the superior oblique and the lateral rectus muscles. The superior division supplies the levator palpebrae superioris and superior rectus muscles. The inferior division supplies the medial rectus, inferior rectus and inferior oblique muscles. This nerve also innervates the striated muscles of the eyelid. Pupillary constriction and lens movement are mediated by this nerve for near vision. In the orbit the inferior division sends branches that enter the ciliary ganglion where they form functional contacts (synapses) with the ganglion cells. The ganglion cells send nerve fibers into the back of the eye where they travel to ultimately innervate the ciliary muscle and the constrictor pupillae muscle.
21623	oculomotor nerve formation	P	The process that gives rise to the oculomotor nerve. This process pertains to the initial formation of a structure from unspecified parts. This motor nerve innervates all extraocular muscles except the superior oblique and the lateral rectus muscles. The superior division supplies the levator palpebrae superioris and superior rectus muscles. The inferior division supplies the medial rectus, inferior rectus and inferior oblique muscles. This nerve also innervates the striated muscles of the eyelid. Pupillary constriction and lens movement are mediated by this nerve for near vision. In the orbit the inferior division sends branches that enter the ciliary ganglion where they form functional contacts (synapses) with the ganglion cells. The ganglion cells send nerve fibers into the back of the eye where they travel to ultimately innervate the ciliary muscle and the constrictor pupillae muscle.
21624	oculomotor nerve structural organization	P	The process that contributes to the act of creating the structural organization of the oculomotor nerve. This process pertains to the physical shaping of a rudimentary structure. This motor nerve innervates all extraocular muscles except the superior oblique and the lateral rectus muscles. The superior division supplies the levator palpebrae superioris and superior rectus muscles. The inferior division supplies the medial rectus, inferior rectus and inferior oblique muscles. This nerve also innervates the striated muscles of the eyelid. Pupillary constriction and lens movement are mediated by this nerve for near vision. In the orbit the inferior division sends branches that enter the ciliary ganglion where they form functional contacts (synapses) with the ganglion cells. The ganglion cells send nerve fibers into the back of the eye where they travel to ultimately innervate the ciliary muscle and the constrictor pupillae muscle.
21625	oculomotor nerve maturation	P	A developmental process, independent of morphogenetic (shape) change, that is required for the oculomotor nerve to attain its fully functional state. This motor nerve innervates all extraocular muscles except the superior oblique and the lateral rectus muscles. The superior division supplies the levator palpebrae superioris and superior rectus muscles. The inferior division supplies the medial rectus, inferior rectus and inferior oblique muscles. This nerve also innervates the striated muscles of the eyelid. Pupillary constriction and lens movement are mediated by this nerve for near vision. In the orbit the inferior division sends branches that enter the ciliary ganglion where they form functional contacts (synapses) with the ganglion cells. The ganglion cells send nerve fibers into the back of the eye where they travel to ultimately innervate the ciliary muscle and the constrictor pupillae muscle.
21626	central nervous system maturation	P	A developmental process, independent of morphogenetic (shape) change, that is required for the central nervous system to attain its fully functional state. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain and spinal cord. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord.
21627	olfactory nerve morphogenesis	P	The process in which the anatomical structure of the olfactory nerve is generated and organized. The olfactory nerve is a collection of sensory nerve rootlets that extend down from the olfactory bulb to the olfactory mucosa of the upper parts of the nasal cavity. This nerve conducts odor information to the brainstem.
21628	olfactory nerve formation	P	The process that gives rise to the olfactory nerve. This process pertains to the initial formation of a structure from unspecified parts. The olfactory nerve is a collection of sensory nerve rootlets that extend down from the olfactory bulb to the olfactory mucosa of the upper parts of the nasal cavity. This nerve conducts odor information to the brainstem.
21629	olfactory nerve structural organization	P	The process that contributes to the act of creating the structural organization of the oculomotor nerve. This process pertains to the physical shaping of a rudimentary structure. The olfactory nerve is a collection of sensory nerve rootlets that extend down from the olfactory bulb to the olfactory mucosa of the upper parts of the nasal cavity. This nerve conducts odor information to the brainstem.
21630	olfactory nerve maturation	P	A developmental process, independent of morphogenetic (shape) change, that is required for the olfactory nerve to attain its fully functional state. The olfactory nerve is a collection of sensory nerve rootlets that extend down from the olfactory bulb to the olfactory mucosa of the upper parts of the nasal cavity. This nerve conducts odor information to the brainstem.
21631	optic nerve morphogenesis	P	The process in which the anatomical structure of the optic nerve is generated and organized. The sensory optic nerve originates from the bipolar cells of the retina and conducts visual information to the brainstem. The optic nerve exits the back of the eye in the orbit, enters the optic canal, and enters the central nervous system at the optic chiasm (crossing) where the nerve fibers become the optic tract just prior to entering the hindbrain.
21632	optic nerve maturation	P	A developmental process, independent of morphogenetic (shape) change, that is required for the optic nerve to attain its fully functional state. The sensory optic nerve originates from the bipolar cells of the retina and conducts visual information to the brainstem. The optic nerve exits the back of the eye in the orbit, enters the optic canal, and enters the central nervous system at the optic chiasm (crossing) where the nerve fibers become the optic tract just prior to entering the hindbrain.
21633	optic nerve structural organization	P	The process that contributes to the act of creating the structural organization of the optic nerve. This process pertains to the physical shaping of a rudimentary structure. The sensory optic nerve originates from the bipolar cells of the retina and conducts visual information to the brainstem. The optic nerve exits the back of the eye in the orbit, enters the optic canal, and enters the central nervous system at the optic chiasm (crossing) where the nerve fibers become the optic tract just prior to entering the hindbrain.
21634	optic nerve formation	P	The process that gives rise to the optic nerve. This process pertains to the initial formation of a structure from unspecified parts. The sensory optic nerve originates from the bipolar cells of the retina and conducts visual information to the brainstem. The optic nerve exits the back of the eye in the orbit, enters the optic canal, and enters the central nervous system at the optic chiasm (crossing) where the nerve fibers become the optic tract just prior to entering the hindbrain.
21635	trigeminal nerve maturation	P	A developmental process, independent of morphogenetic (shape) change, that is required for the trigeminal nerve to attain its fully functional state. The trigeminal nerve is composed of three large branches. They are the ophthalmic (V1, sensory), maxillary (V2, sensory) and mandibular (V3, motor and sensory) branches. The sensory ophthalmic branch travels through the superior orbital fissure and passes through the orbit to reach the skin of the forehead and top of the head. The maxillary nerve contains sensory branches that reach the pterygopalatine fossa via the inferior orbital fissure (face, cheek and upper teeth) and pterygopalatine canal (soft and hard palate, nasal cavity and pharynx). The motor part of the mandibular branch is distributed to the muscles of mastication, the mylohyoid muscle and the anterior belly of the digastric. The mandibular nerve also innervates the tensor veli palatini and tensor tympani muscles. The sensory part of the mandibular nerve is composed of branches that carry general sensory information from the mucous membranes of the mouth and cheek, anterior two-thirds of the tongue, lower teeth, skin of the lower jaw, side of the head and scalp and meninges of the anterior and middle cranial fossae.
21636	trigeminal nerve morphogenesis	P	The process in which the anatomical structure of the trigeminal nerve is generated and organized. The trigeminal nerve is composed of three large branches. They are the ophthalmic (V1, sensory), maxillary (V2, sensory) and mandibular (V3, motor and sensory) branches. The sensory ophthalmic branch travels through the superior orbital fissure and passes through the orbit to reach the skin of the forehead and top of the head. The maxillary nerve contains sensory branches that reach the pterygopalatine fossa via the inferior orbital fissure (face, cheek and upper teeth) and pterygopalatine canal (soft and hard palate, nasal cavity and pharynx). The motor part of the mandibular branch is distributed to the muscles of mastication, the mylohyoid muscle and the anterior belly of the digastric. The mandibular nerve also innervates the tensor veli palatini and tensor tympani muscles. The sensory part of the mandibular nerve is composed of branches that carry general sensory information from the mucous membranes of the mouth and cheek, anterior two-thirds of the tongue, lower teeth, skin of the lower jaw, side of the head and scalp and meninges of the anterior and middle cranial fossae.
21637	trigeminal nerve structural organization	P	The process that contributes to the act of creating the structural organization of the oculomotor nerve. This process pertains to the physical shaping of a rudimentary structure. The trigeminal nerve is composed of three large branches. They are the ophthalmic (V1, sensory), maxillary (V2, sensory) and mandibular (V3, motor and sensory) branches. The sensory ophthalmic branch travels through the superior orbital fissure and passes through the orbit to reach the skin of the forehead and top of the head. The maxillary nerve contains sensory branches that reach the pterygopalatine fossa via the inferior orbital fissure (face, cheek and upper teeth) and pterygopalatine canal (soft and hard palate, nasal cavity and pharynx). The motor part of the mandibular branch is distributed to the muscles of mastication, the mylohyoid muscle and the anterior belly of the digastric. The mandibular nerve also innervates the tensor veli palatini and tensor tympani muscles. The sensory part of the mandibular nerve is composed of branches that carry general sensory information from the mucous membranes of the mouth and cheek, anterior two-thirds of the tongue, lower teeth, skin of the lower jaw, side of the head and scalp and meninges of the anterior and middle cranial fossae.
21638	trigeminal nerve formation	P	The process that gives rise to the trigeminal nerve. This process pertains to the initial formation of a structure from unspecified parts. The trigeminal nerve is composed of three large branches. They are the ophthalmic (V1, sensory), maxillary (V2, sensory) and mandibular (V3, motor and sensory) branches. The sensory ophthalmic branch travels through the superior orbital fissure and passes through the orbit to reach the skin of the forehead and top of the head. The maxillary nerve contains sensory branches that reach the pterygopalatine fossa via the inferior orbital fissure (face, cheek and upper teeth) and pterygopalatine canal (soft and hard palate, nasal cavity and pharynx). The motor part of the mandibular branch is distributed to the muscles of mastication, the mylohyoid muscle and the anterior belly of the digastric. The mandibular nerve also innervates the tensor veli palatini and tensor tympani muscles. The sensory part of the mandibular nerve is composed of branches that carry general sensory information from the mucous membranes of the mouth and cheek, anterior two-thirds of the tongue, lower teeth, skin of the lower jaw, side of the head and scalp and meninges of the anterior and middle cranial fossae.
21639	trochlear nerve morphogenesis	P	The process in which the anatomical structure of the trochlear nerve is generated and organized. The trochlear nerve is a motor nerve and is the only cranial nerve to exit the brain dorsally. The trochlear nerve innervates the superior oblique muscle.
21640	trochlear nerve maturation	P	A developmental process, independent of morphogenetic (shape) change, that is required for the trochlear nerve to attain its fully functional state. The trochlear nerve is a motor nerve and is the only cranial nerve to exit the brain dorsally. The trochlear nerve innervates the superior oblique muscle.
21641	trochlear nerve structural organization	P	The process that contributes to the act of creating the structural organization of the trochlear nerve. This process pertains to the physical shaping of a rudimentary structure. The trochlear nerve is a motor nerve and is the only cranial nerve to exit the brain dorsally. The trochlear nerve innervates the superior oblique muscle.
21642	trochlear nerve formation	P	The process that gives rise to the trochlear nerve. This process pertains to the initial formation of a structure from unspecified parts. The trochlear nerve is a motor nerve and is the only cranial nerve to exit the brain dorsally. The trochlear nerve innervates the superior oblique muscle.
21643	vagus nerve maturation	P	A developmental process, independent of morphogenetic (shape) change, that is required for the vagus nerve to attain its fully functional state. This nerve is primarily sensory but also has visceromotor components. It originates in the brain stem and controls many autonomic functions of the heart, lungs, stomach, pharynx, larynx, trachea, esophagus and other gastrointestinal tract components. It controls some motor functions such as speech. The sensory branches mediate sensation from the pharynx, larynx, thorax and abdomen; it also innervates taste buds in the epiglottis.
21644	vagus nerve morphogenesis	P	The process in which the anatomical structure of the vagus nerve is generated and organized. This nerve is primarily sensory but also has visceromotor components. It originates in the brain stem and controls many autonomic functions of the heart, lungs, stomach, pharynx, larynx, trachea, esophagus and other gastrointestinal tract components. It controls some motor functions such as speech. The sensory branches mediate sensation from the pharynx, larynx, thorax and abdomen; it also innervates taste buds in the epiglottis.
21645	vagus nerve structural organization	P	The process that contributes to the act of creating the structural organization of the vagus nerve. This process pertains to the physical shaping of a rudimentary structure. This nerve is primarily sensory but also has visceromotor components. It originates in the brain stem and controls many autonomic functions of the heart, lungs, stomach, pharynx, larynx, trachea, esophagus and other gastrointestinal tract components. It controls some motor functions such as speech. The sensory branches mediate sensation from the pharynx, larynx, thorax and abdomen; it also innervates taste buds in the epiglottis.
21646	vagus nerve formation	P	The process that gives rise to the vagus nerve. This process pertains to the initial formation of a structure from unspecified parts. This nerve is primarily sensory but also has visceromotor components. It originates in the brain stem and controls many autonomic functions of the heart, lungs, stomach, pharynx, larynx, trachea, esophagus and other gastrointestinal tract components. It controls some motor functions such as speech. The sensory branches mediate sensation from the pharynx, larynx, thorax and abdomen; it also innervates taste buds in the epiglottis.
21647	vestibulocochlear nerve maturation	P	A developmental process, independent of morphogenetic (shape) change, that is required for the vestibulocochlear nerve to attain its fully functional state. This sensory nerve innervates the membranous labyrinth of the inner ear. The vestibular branch innervates the vestibular apparatus that senses head position changes relative to gravity. The auditory branch innervates the cochlear duct, which is connected to the three bony ossicles which transduce sound waves into fluid movement in the cochlea.
21648	vestibulocochlear nerve morphogenesis	P	The process in which the anatomical structure of the vestibulocochlear nerve is generated and organized. This sensory nerve innervates the membranous labyrinth of the inner ear. The vestibular branch innervates the vestibular apparatus that senses head position changes relative to gravity. The auditory branch innervates the cochlear duct, which is connected to the three bony ossicles which transduce sound waves into fluid movement in the cochlea.
21649	vestibulocochlear nerve structural organization	P	The process that contributes to the act of creating the structural organization of the vestibulocochlear nerve. This process pertains to the physical shaping of a rudimentary structure. This sensory nerve innervates the membranous labyrinth of the inner ear. The vestibular branch innervates the vestibular apparatus that senses head position changes relative to gravity. The auditory branch innervates the cochlear duct, which is connected to the three bony ossicles which transduce sound waves into fluid movement in the cochlea.
21650	vestibulocochlear nerve formation	P	The process that gives rise to the vestibulocochlear nerve. This process pertains to the initial formation of a structure from unspecified parts. This sensory nerve innervates the membranous labyrinth of the inner ear. The vestibular branch innervates the vestibular apparatus that senses head position changes relative to gravity. The auditory branch innervates the cochlear duct, which is connected to the three bony ossicles which transduce sound waves into fluid movement in the cochlea.
21651	rhombomere 1 morphogenesis	P	The process in which the anatomical structure of rhombomere 1 is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order.
21652	rhombomere 1 formation	P	The process that gives rise to rhombomere 1. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.
21653	rhombomere 1 structural organization	P	The process that contributes to creating the structural organization of rhombomere 1. This process pertains to the physical shaping of a rudimentary structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order.
21654	rhombomere boundary formation	P	The process that gives rise to a rhombomere boundary. This process pertains to the initial formation of a boundary delimiting a rhombomere. Rhombomeres are transverse segments of the developing rhombencephalon that are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.
21655	rhombomere 2 morphogenesis	P	The process in which the anatomical structure of rhombomere 2 is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order.
21656	rhombomere 2 structural organization	P	The process that contributes to creating the structural organization of rhombomere 2. This process pertains to the physical shaping of a rudimentary structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order.
21657	rhombomere 2 formation	P	The process that gives rise to rhombomere 2. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.
21658	rhombomere 3 morphogenesis	P	The process in which the anatomical structure of rhombomere 3 is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order.
21659	rhombomere 3 structural organization	P	The process that contributes to creating the structural organization of rhombomere 3. This process pertains to the physical shaping of a rudimentary structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order.
21660	rhombomere 3 formation	P	The process that gives rise to rhombomere 3. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.
21661	rhombomere 4 morphogenesis	P	The process in which the anatomical structure of rhombomere 4 is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order.
21662	rhombomere 4 structural organization	P	The process that contributes to creating the structural organization of rhombomere 4. This process pertains to the physical shaping of a rudimentary structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order.
21663	rhombomere 4 formation	P	The process that gives rise to rhombomere 4. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.
21664	rhombomere 5 morphogenesis	P	The process in which the anatomical structures of rhombomere 5 are generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order.
21665	rhombomere 5 structural organization	P	The process that contributes to creating the structural organization of rhombomere 5. This process pertains to the physical shaping of a rudimentary structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order.
21666	rhombomere 5 formation	P	The process that gives rise to rhombomere 5. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.
21667	rhombomere 6 morphogenesis	P	The process in which the anatomical structure of rhombomere 6 is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order.
21668	rhombomere 6 structural organization	P	The process that contributes to creating the structural organization of rhombomere 6. This process pertains to the physical shaping of a rudimentary structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order.
21669	rhombomere 6 formation	P	The process that gives rise to rhombomere 6. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.
21670	lateral ventricle development	P	The process whose specific outcome is the progression of the lateral ventricles over time, from the formation to the mature structure. The two lateral ventricles are a cavity in each of the cerebral hemispheres derived from the cavity of the embryonic neural tube. They are separated from each other by the septum pellucidum, and each communicates with the third ventricle by the foramen of Monro, through which also the choroid plexuses of the lateral ventricles become continuous with that of the third ventricle.
21671	rhombomere 7 morphogenesis	P	The process in which the anatomical structure of rhombomere 7 is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order.
21672	rhombomere 7 structural organization	P	The process that contributes to creating the structural organization of rhombomere 7. This process pertains to the physical shaping of a rudimentary structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order.
21673	rhombomere 7 formation	P	The process that gives rise to rhombomere 7. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.
21674	rhombomere 8 morphogenesis	P	The process in which the anatomical structure of rhombomere 8 is generated and organized. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order.
21675	nerve development	P	The process whose specific outcome is the progression of a nerve over time, from its formation to the mature structure.
21676	rhombomere 8 structural organization	P	The process that contributes to creating the structural organization of rhombomere 8. This process pertains to the physical shaping of a rudimentary structure. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in an anterior to posterior order.
21677	rhombomere 8 formation	P	The process that gives rise to rhombomere 8. This process pertains to the initial formation of a structure from unspecified parts. Rhombomeres are transverse segments of the developing rhombencephalon. Rhombomeres are lineage restricted, express different genes from one another, and adopt different developmental fates. Rhombomeres are numbered in anterior to posterior order.
21678	third ventricle development	P	The process whose specific outcome is the progression of the third ventricle over time, from its formation to the mature structure. The third ventricle is the narrow cleft inferior to the corpus callosum, within the diencephalon, between the paired thalami. Its floor is formed by the hypothalamus, its anterior wall by the lamina terminalis, and its roof by ependyma, and it communicates with the fourth ventricle by the cerebral aqueduct, and with the lateral ventricles by the interventricular foramina.
21679	cerebellar molecular layer development	P	The process whose specific outcome is the progression of the cerebellar molecular layer nerve over time, from its formation to the mature structure. The molecular layer is the outermost layer of the cerebellar cortex. It contains the parallel fibers of the granule cells, interneurons such as stellate and basket cells, and the dendrites of the underlying Purkinje cells.
21680	cerebellar Purkinje cell layer development	P	The process whose specific outcome is the progression of the cerebellar Purkinje cell layer over time, from its formation to the mature structure. The Purkinje cell layer lies just underneath the molecular layer of the cerebellar cortex. It contains the neuronal cell bodies of the Purkinje cells that are arranged side by side in a single layer. Candelabrum interneurons are vertically oriented between the Purkinje cells. Purkinje neurons are inhibitory and provide the output of the cerebellar cortex through axons that project into the white matter. Extensive dendritic trees from the Purkinje cells extend upward in a single plane into the molecular layer where they synapse with parallel fibers of granule cells.
21681	cerebellar granular layer development	P	The process whose specific outcome is the progression of the cerebellar granule layer over time, from its formation to the mature structure. The granular layer is the innermost layer of the cerebellar cortex. This layer contains densely packed small neurons, mostly granule cells. Some Golgi cells are found at the outer border. Granule neurons send parallel fibers to the upper molecular layer, where they synapse with Purkinje cell dendrites. Mossy fibers from the pontine nuclei in the white matter synapse with granule cell axons, Golgi cell axons and unipolar brush interneuron axons at cerebellar glomeruli in the granule cell layer.
21682	nerve maturation	P	A developmental process, independent of morphogenetic (shape) change, that is required for a nerve to attain its fully functional state.
21683	cerebellar granular layer morphogenesis	P	The process in which the anatomical structure of the cerebellar granular layer is generated and organized. The granular layer is the innermost layer of the cerebellar cortex. This layer contains densely packed small neurons, mostly granule cells. Some Golgi cells are found at the outer border. Granule neurons send parallel fibers to the upper molecular layer, where they synapse with Purkinje cell dendrites. Mossy fibers from the pontine nuclei in the white matter synapse with granule cell axons, Golgi cell axons and unipolar brush interneuron axons at cerebellar glomeruli in the granule cell layer.
21684	cerebellar granular layer formation	P	The process that gives rise to the cerebellar granule layer. This process pertains to the initial formation of a structure from unspecified parts. The granular layer is the innermost layer of the cerebellar cortex. This layer contains densely packed small neurons, mostly granule cells. Some Golgi cells are found at the outer border. Granule neurons send parallel fibers to the upper molecular layer, where they synapse with Purkinje cell dendrites. Mossy fibers from the pontine nuclei in the white matter synapse with granule cell axons, Golgi cell axons and unipolar brush interneuron axons at cerebellar glomeruli in the granule cell layer.
21685	cerebellar granular layer structural organization	P	The process that contributes to the act of creating the structural organization of the cerebellar granule layer. This process pertains to the physical shaping of a rudimentary structure. The granular layer is the innermost layer of the cerebellar cortex. This layer contains densely packed small neurons, mostly granule cells. Some Golgi cells are found at the outer border. Granule neurons send parallel fibers to the upper molecular layer, where they synapse with Purkinje cell dendrites. Mossy fibers from the pontine nuclei in the white matter synapse with granule cell axons, Golgi cell axons and unipolar brush interneuron axons at cerebellar glomeruli in the granule cell layer.
21686	cerebellar granular layer maturation	P	A developmental process, independent of morphogenetic (shape) change, that is required for the cerebellar granular layer to attain its fully functional state. The granular layer is the innermost layer of the cerebellar cortex. This layer contains densely packed small neurons, mostly granule cells. Some Golgi cells are found at the outer border. Granule neurons send parallel fibers to the upper molecular layer, where they synapse with Purkinje cell dendrites. Mossy fibers from the pontine nuclei in the white matter synapse with granule cell axons, Golgi cell axons and unipolar brush interneuron axons at cerebellar glomeruli in the granule cell layer.
21687	cerebellar molecular layer morphogenesis	P	The process in which the anatomical structure of the cerebellar molecular layer is generated and organized. The molecular layer is the outermost layer of the cerebellar cortex. It contains the parallel fibers of the granule cells, interneurons such as stellate and basket cells, and the dendrites of the underlying Purkinje cells.
21688	cerebellar molecular layer formation	P	The process that gives rise to the cerebellar molecular layer. This process pertains to the initial formation of a structure from unspecified parts. The molecular layer is the outermost layer of the cerebellar cortex. It contains the parallel fibers of the granule cells, interneurons such as stellate and basket cells, and the dendrites of the underlying Purkinje cells.
21689	cerebellar molecular layer structural organization	P	The process that contributes to the act of creating the structural organization of the cerebellar molecular layer. This process pertains to the physical shaping of a rudimentary structure. The molecular layer is the outermost layer of the cerebellar cortex. It contains the parallel fibers of the granule cells, interneurons such as stellate and basket cells, and the dendrites of the underlying Purkinje cells.
21690	cerebellar molecular layer maturation	P	A developmental process, independent of morphogenetic (shape) change, that is required for the cerebellar molecular layer to attain its fully functional state. The molecular layer is the outermost layer of the cerebellar cortex. It contains the parallel fibers of the granule cells, interneurons such as stellate and basket cells, and the dendrites of the underlying Purkinje cells.
21691	cerebellar Purkinje cell layer maturation	P	A developmental process, independent of morphogenetic (shape) change, that is required for the cerebellar Purkinje cell layer to attain its fully functional state. The Purkinje cell layer lies just underneath the molecular layer of the cerebellar cortex. It contains the neuronal cell bodies of the Purkinje cells that are arranged side by side in a single layer. Candelabrum interneurons are vertically oriented between the Purkinje cells. Purkinje neurons are inhibitory and provide the output of the cerebellar cortex through axons that project into the white matter. Extensive dendritic trees from the Purkinje cells extend upward in a single plane into the molecular layer where they synapse with parallel fibers of granule cells.
21692	cerebellar Purkinje cell layer morphogenesis	P	The process in which the anatomical structure of the cerebellar Purkinje cell layer is generated and organized. The Purkinje cell layer lies just underneath the molecular layer of the cerebellar cortex. It contains the neuronal cell bodies of the Purkinje cells that are arranged side by side in a single layer. Candelabrum interneurons are vertically oriented between the Purkinje cells. Purkinje neurons are inhibitory and provide the output of the cerebellar cortex through axons that project into the white matter. Extensive dendritic trees from the Purkinje cells extend upward in a single plane into the molecular layer where they synapse with parallel fibers of granule cells.
21693	cerebellar Purkinje cell layer structural organization	P	The process that contributes to the act of creating the structural organization of the cerebellar Purkinje cell layer. This process pertains to the physical shaping of a rudimentary structure. The Purkinje cell layer lies just underneath the molecular layer of the cerebellar cortex. It contains the neuronal cell bodies of the Purkinje cells that are arranged side by side in a single layer. Candelabrum interneurons are vertically oriented between the Purkinje cells. Purkinje neurons are inhibitory and provide the output of the cerebellar cortex through axons that project into the white matter. Extensive dendritic trees from the Purkinje cells extend upward in a single plane into the molecular layer where they synapse with parallel fibers of granule cells.
21694	cerebellar Purkinje cell layer formation	P	The process that gives rise to the cerebellar Purkinje cell layer. This process pertains to the initial formation of a structure from unspecified parts. The Purkinje cell layer lies just underneath the molecular layer of the cerebellar cortex. It contains the neuronal cell bodies of the Purkinje cells that are arranged side by side in a single layer. Candelabrum interneurons are vertically oriented between the Purkinje cells. Purkinje neurons are inhibitory and provide the output of the cerebellar cortex through axons that project into the white matter. Extensive dendritic trees from the Purkinje cells extend upward in a single plane into the molecular layer where they synapse with parallel fibers of granule cells.
21695	cerebellar cortex development	P	The process whose specific outcome is the progression of the cerebellar cortex over time, from its formation to the mature structure. The cerebellar cortex is a thin mantle of gray matter that covers the surface of each cerebral hemisphere. It has a characteristic morphology with convolutions (gyri) and crevices (sulci) that have specific functions. Six layers of nerve cells and the nerve pathways that connect them comprise the cerebellar cortex. Together, these regions are responsible for the processes of conscious thought, perception, emotion and memory as well as advanced motor function.
21696	cerebellar cortex morphogenesis	P	The process in which the anatomical structure of the cranial nerves are generated and organized. The cerebellar cortex is a thin mantle of gray matter that covers the surface of each cerebral hemisphere. It has a characteristic morphology with convolutions (gyri) and crevices (sulci) that have specific functions. Six layers of nerve cells and the nerve pathways that connect them comprise the cerebellar cortex. Together, these regions are responsible for the processes of conscious thought, perception, emotion and memory as well as advanced motor function.
21697	cerebellar cortex formation	P	The process that gives rise to the cerebellar cortex. This process pertains to the initial formation of a structure from unspecified parts. The cerebellar cortex is a thin mantle of gray matter that covers the surface of each cerebral hemisphere. It has a characteristic morphology with convolutions (gyri) and crevices (sulci) that have specific functions. Six layers of nerve cells and the nerve pathways that connect them comprise the cerebellar cortex. Together, these regions are responsible for the processes of conscious thought, perception, emotion and memory as well as advanced motor function.
21698	cerebellar cortex structural organization	P	The process that contributes to the act of creating the structural organization of the cerebellar cortex. This process pertains to the physical shaping of a rudimentary structure. The cerebellar cortex is a thin mantle of gray matter that covers the surface of each cerebral hemisphere. It has a characteristic morphology with convolutions (gyri) and crevices (sulci) that have specific functions. Six layers of nerve cells and the nerve pathways that connect them comprise the cerebellar cortex. Together, these regions are responsible for the processes of conscious thought, perception, emotion and memory as well as advanced motor function.
21699	cerebellar cortex maturation	P	A developmental process, independent of morphogenetic (shape) change, that is required for the cerebellar cortex to attain its fully functional state. The cerebellar cortex is a thin mantle of gray matter that covers the surface of each cerebral hemisphere. It has a characteristic morphology with convolutions (gyri) and crevices (sulci) that have specific functions. Six layers of nerve cells and the nerve pathways that connect them comprise the cerebellar cortex. Together, these regions are responsible for the processes of conscious thought, perception, emotion and memory as well as advanced motor function.
21700	developmental maturation	P	A developmental process, independent of morphogenetic (shape) change, that is required for an anatomical structure, cell or cellular component to attain its fully functional state.
21701	cerebellar Golgi cell differentiation	P	The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature cerebellar Golgi cell. Differentiation includes the processes involved in commitment of a neuroblast to a Golgi cell fate. A cerebellar Golgi cell is an inhibitory GABAergic interneuron found in the cerebellar cortex.
21702	cerebellar Purkinje cell differentiation	P	The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature cerebellar Purkinje cell. Differentiation includes the processes involved in commitment of a neuroblast to a Purkinje cell fate. A Purkinje cell is an inhibitory GABAergic neuron found in the cerebellar cortex that projects to the deep cerebellar nuclei and brain stem.
21703	locus ceruleus development	P	The process whose specific outcome is the progression of the locus ceruleus over time, from its formation to the mature structure. The locus ceruleus is a dense cluster of neurons within the dorsorostral pons. This nucleus is the major location of neurons that release norepinephrine throughout the brain, and is responsible for physiological responses to stress and panic.
21704	locus ceruleus morphogenesis	P	The process in which the anatomical structure of the locus ceruleus is generated and organized. In mice, the locus ceruleus is a dense cluster of neurons within the dorsorostral pons. This nucleus is the major location of neurons that release norepinephrine throughout the brain, and is responsible for physiological responses to stress and panic.
21705	locus ceruleus formation	P	The process that gives rise to the locus ceruleus. This process pertains to the initial formation of a structure from unspecified parts. In mice, the locus ceruleus is a dense cluster of neurons within the dorsorostral pons. This nucleus is the major location of neurons that release norepinephrine throughout the brain, and is responsible for physiological responses to stress and panic.
21706	locus ceruleus maturation	P	A developmental process, independent of morphogenetic (shape) change, that is required for the locus ceruleus to attain its fully functional state. The locus ceruleus is a dense cluster of neurons within the dorsorostral pons. This nucleus is the major location of neurons that release norepinephrine throughout the brain, and is responsible for physiological responses to stress and panic.
21707	cerebellar granule cell differentiation	P	The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature cerebellar granule cell. Differentiation includes the processes involved in commitment of a neuroblast to a granule cell fate. A granule cell is a glutamatergic interneuron found in the cerebellar cortex.
21708	Lugaro cell differentiation	P	The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature Lugaro cell. Differentiation includes the processes involved in commitment of a neuroblast to a Lugaro cell fate. A Lugaro cell is an inhibitory GABAergic interneuron found in the cerebellar cortex.
21709	cerebellar basket cell differentiation	P	The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature cerebellar basket cell. Differentiation includes the processes involved in commitment of a neuroblast to a cerebellar basket cell fate. A cerebellar basket cell is an inhibitory GABAergic interneuron found in the cerebellar cortex.
21710	cerebellar stellate cell differentiation	P	The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature cerebellar stellate cell. Differentiation includes the processes involved in commitment of a neuroblast to a cerebellar stellate cell fate. A cerebellar stellate cell is an inhibitory GABAergic interneuron found in the cerebellar cortex.
21711	cerebellar unipolar brush cell differentiation	P	The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature unipolar brush cell in the cerebellum. Differentiation includes the processes involved in commitment of a neuroblast to a unipolar brush cell fate. A unipolar brush cell is a glutamatergic interneuron found in the cerebellar cortex.
21712	candelabrum cell differentiation	P	The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature candelabrum cell. Differentiation includes the processes involved in commitment of a neuroblast to a candelabrum cell fate. A candelabrum cell is an inhibitory GABAergic interneuron found in the cerebellar cortex.
21713	inferior olivary nucleus development	P	The process whose specific outcome is the progression of the inferior olivary nucleus over time, from its formation to the mature structure. The inferior olivary nucleus is a capsule-shaped structure in the ventral medulla located just lateral and dorsal to the medullary pyramids. Neurons in the inferior olivary nucleus are the source of climbing fiber input to the cerebellar cortex; these neurons have been implicated in various functions, such as learning and timing of movements.
21714	inferior olivary nucleus morphogenesis	P	The process in which the anatomical structure of the inferior olivary nucleus is generated and organized. The inferior olivary nucleus is a capsule-shaped structure in the ventral medulla located just lateral and dorsal to the medullary pyramids. Neurons in the inferior olivary nucleus are the source of climbing fiber input to the cerebellar cortex; these neurons have been implicated in various functions, such as learning and timing of movements.
21715	inferior olivary nucleus formation	P	The process that gives rise to the inferior olivary nucleus. This process pertains to the initial formation of a structure from unspecified parts. The inferior olivary nucleus is a capsule-shaped structure in the ventral medulla located just lateral and dorsal to the medullary pyramids. Neurons in the inferior olivary nucleus are the source of climbing fiber input to the cerebellar cortex; these neurons have been implicated in various functions, such as learning and timing of movements.
21716	inferior olivary nucleus structural organization	P	The process that contributes to the act of creating the structural organization of the inferior olivary nucleus structure. The inferior olivary nucleus is a capsule-shaped structure in the ventral medulla located just lateral and dorsal to the medullary pyramids. Neurons in the inferior olivary nucleus are the source of climbing fiber input to the cerebellar cortex; these neurons have been implicated in various functions, such as learning and timing of movements.
21717	inferior olivary nucleus maturation	P	A developmental process, independent of morphogenetic (shape) change, that is required for the inferior olivary nucleus to attain its fully functional state. The inferior olivary nucleus is a capsule-shaped structure in the ventral medulla located just lateral and dorsal to the medullary pyramids. Neurons in the inferior olivary nucleus are the source of climbing fiber input to the cerebellar cortex; these neurons have been implicated in various functions, such as learning and timing of movements.
21718	superior olivary nucleus development	P	The process whose specific outcome is the progression of the superior olivary nucleus over time, from its formation to the mature structure. In mice, the superior olivary nucleus is a small cylindrical mass on the dorsal surface of the lateral part of the trapezoid body of the pons, and it is situated immediately above the inferior olivary nucleus. It receives projections from the cochlear nucleus and thus is involved in the perception of sound.
21719	superior olivary nucleus morphogenesis	P	The process in which the anatomical structure of the superior olivary nucleus is generated and organized. In mice, the superior olivary nucleus is a small cylindrical mass on the dorsal surface of the lateral part of the trapezoid body of the pons, and it is situated immediately above the inferior olivary nucleus. It receives projections from the cochlear nucleus and thus is involved in the perception of sound.
21720	superior olivary nucleus formation	P	The process that gives rise to the superior olivary nucleus. This process pertains to the initial formation of a structure from unspecified parts. In mice, the superior olivary nucleus is a small cylindrical mass on the dorsal surface of the lateral part of the trapezoid body of the pons, and it is situated immediately above the inferior olivary nucleus. It receives projections from the cochlear nucleus and thus is involved in the perception of sound.
21721	superior olivary nucleus structural organization	P	The process that contributes to the act of creating the structural organization of the superior olivary nucleus structure. In mice, the superior olivary nucleus is a small cylindrical mass on the dorsal surface of the lateral part of the trapezoid body of the pons, and it is situated immediately above the inferior olivary nucleus. It receives projections from the cochlear nucleus and thus is involved in the perception of sound.
21722	superior olivary nucleus maturation	P	A developmental process, independent of morphogenetic (shape) change, that is required for the superior olivary nucleus to attain its fully functional state. The superior olivary nucleus is a small cylindrical mass on the dorsal surface of the lateral part of the trapezoid body of the pons, and it is situated immediately above the inferior olivary nucleus. It receives projections from the cochlear nucleus and thus is involved in the perception of sound.
21723	medullary reticular formation development	P	The process whose specific outcome is the progression of the medullary reticular formation over time, from its formation to the mature structure. The medullary reticular formation is a series of brain nuclei located in the medulla oblongata.
21724	inferior raphe nucleus development	P	The process whose specific outcome is the progression of the inferior raphe nucleus over time, from its formation to the mature structure.
21725	superior raphe nucleus development	P	The process whose specific outcome is the progression of the superior raphe nucleus over time, from its formation to the mature structure.
21726	lateral reticular nucleus development	P	The process whose specific outcome is the progression of the lateral reticular nucleus over time, from its formation to the mature structure.
21727	intermediate reticular formation development	P	The process whose specific outcome is the progression of the intermediate reticular formation over time, from its formation to the mature structure.
21728	inferior reticular formation development	P	The process whose specific outcome is the progression of the inferior reticular formation over time, from its formation to the mature structure.
21729	superior reticular formation development	P	The process whose specific outcome is the progression of the superior reticular formation over time, from its formation to the mature structure.
21730	trigeminal sensory nucleus development	P	The process whose specific outcome is the progression of the trigeminal sensory nucleus over time, from its formation to the mature structure.
21731	trigeminal motor nucleus development	P	The process whose specific outcome is the progression of the trigeminal motor nucleus over time, from its formation to the mature structure.
21732	midbrain-hindbrain boundary maturation	P	A developmental process, independent of morphogenetic (shape) change, that is required for the midbrain-hindbrain boundary to attain its fully functional state. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. An organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate.
21735	dentate nucleus development	P	The process whose specific outcome is the progression of the dentate nucleus over time, from its formation to the mature structure.
21736	globose nucleus development	P	The process whose specific outcome is the progression of the globose nucleus over time, from its formation to the mature structure.
21737	emboliform nucleus development	P	The process whose specific outcome is the progression of the emboliform nucleus over time, from its formation to the mature structure.
21738	fastigial nucleus development	P	The process whose specific outcome is the progression of the fastigial nucleus over time, from its formation to the mature structure.
21739	mesencephalic trigeminal nucleus development	P	The process whose specific outcome is the progression of the mesencephalic trigeminal nucleus over time, from its formation to the mature structure.
21740	principal sensory nucleus of trigeminal nerve development	P	The process whose specific outcome is the progression of the pontine nucleus over time, from its formation to the mature structure.
21741	spinal trigeminal nucleus development	P	The process whose specific outcome is the progression of the spinal trigeminal nucleus over time, from its formation to the mature structure.
21742	abducens nucleus development	P	The process whose specific outcome is the progression of the abducens nucleus over time, from its formation to the mature structure.
21743	hypoglossal nucleus development	P	The process whose specific outcome is the progression of the hypoglossal nucleus over time, from its formation to the mature structure.
21744	dorsal motor nucleus of vagus nerve development	P	The process whose specific outcome is the progression of the dorsal motor nucleus of the vagus nerve over time, from its formation to the mature structure.
21745	nucleus ambiguus development	P	The process whose specific outcome is the progression of the nucleus ambiguus over time, from its formation to the mature structure.
21746	solitary nucleus development	P	The process whose specific outcome is the progression of the solitary nucleus over time, from its formation to the mature structure.
21747	cochlear nucleus development	P	The process whose specific outcome is the progression of the cochlear nucleus over time, from its formation to the mature structure.
21748	dorsal cochlear nucleus development	P	The process whose specific outcome is the progression of the dorsal cochlear nucleus over time, from its formation to the mature structure.
21749	ventral cochlear nucleus development	P	The process whose specific outcome is the progression of the ventral cochlear nucleus over time, from its formation to the mature structure.
21750	vestibular nucleus development	P	The process whose specific outcome is the progression of the vestibular nucleus over time, from its formation to the mature structure.
21751	salivary nucleus development	P	The process whose specific outcome is the progression of a salivary nucleus over time, from its formation to the mature structure.
21752	inferior salivary nucleus development	P	The process whose specific outcome is the progression of the inferior salivary nucleus over time, from its formation to the mature structure.
21753	superior salivary nucleus development	P	The process whose specific outcome is the progression of the superior salivary nucleus over time, from its formation to the mature structure.
21754	facial nucleus development	P	The process whose specific outcome is the progression of the facial nucleus over time, from its formation to the mature structure.
21755	eurydendroid cell differentiation	P	The process in which neuroblasts acquire specialized structural and/or functional features that characterize the mature eurydendroid cell. Differentiation includes the processes involved in commitment of a neuroblast to a eurydendroid cell fate. A eurydendroid cell is an efferent neuron found in the cerebellar cortex of teleosts.
21756	striatum development	P	The progression of the striatum over time from its initial formation until its mature state. The striatum is a region of the forebrain consisting of the caudate nucleus, putamen and fundus striati.
21757	caudate nucleus development	P	The progression of the caudate nucleus over time from its initial formation until its mature state. The caudate nucleus is the C-shaped structures of the striatum containing input neurons involved with control of voluntary movement in the brain.
21758	putamen development	P	The progression of the putamen over time from its initial formation until its mature state. The putamen is the lens-shaped basal ganglion involved with control of voluntary movement in the brain.
21759	globus pallidus development	P	The progression of the globus pallidus over time from its initial formation until its mature state. The globus pallidus is one of the basal ganglia involved with control of voluntary movement in the brain.
21761	limbic system development	P	The progression of the limbic system over time from its initial formation until its mature state. The limbic system is a collection of structures in the brain involved in emotion, motivation and emotional aspects of memory.
21762	substantia nigra development	P	The progression of the substantia nigra over time from its initial formation until its mature state. The substantia nigra is the layer of gray substance that separates the posterior parts of the cerebral peduncles (tegmentum mesencephali) from the anterior parts; it normally includes a posterior compact part with many pigmented cells (pars compacta) and an anterior reticular part whose cells contain little pigment (pars reticularis).
21763	subthalamic nucleus development	P	The progression of the subthalamic nucleus over time from its initial formation until its mature state. The subthalamic nucleus is the lens-shaped nucleus located in the ventral part of the subthalamus on the inner aspect of the internal capsule that is concerned with the integration of somatic motor function.
21764	amygdala development	P	The progression of the amygdala over time from its initial formation until its mature state. The amygdala is an almond-shaped set of neurons in the medial temporal lobe of the brain that play a key role in processing emotions such as fear and pleasure.
21765	cingulate gyrus development	P	The progression of the cingulate gyrus over time from its initial formation until its mature state. The cingulate gyrus is a ridge in the cerebral cortex located dorsal to the corpus callosum.
21766	hippocampus development	P	The progression of the hippocampus over time from its initial formation until its mature state.
21767	mammillary body development	P	The progression of the mammillary body over time from its initial formation until its mature state. The mammillary body is a protrusion at the posterior end of the hypothalamus that contains hypothalamic nuclei.
21768	nucleus accumbens development	P	The progression of the nucleus accumbens over time from its initial formation until its mature state. The nucleus accumbens is a collection of pleomorphic cells in the caudal part of the anterior horn of the lateral ventricle, in the region of the olfactory tubercle, lying between the head of the caudate nucleus and the anterior perforated substance. It is part of the ventral striatum, a composite structure considered part of the basal ganglia.
21769	orbitofrontal cortex development	P	The progression of the orbitofrontal cortex over time from its initial formation until its mature state. The orbitofrontal cortex is a cerebral cortex region located in the frontal lobe.
21770	parahippocampal gyrus development	P	The progression of the parahippocampal gyrus over time from its initial formation until its mature state. The parahippocampal gyrus is a ridge in the cerebral cortex.
21771	lateral geniculate nucleus development	P	The progression of the lateral geniculate nucleus over time from its initial formation until its mature state. The lateral geniculate nucleus is the primary processor of visual information received from the retina.
21772	olfactory bulb development	P	The progression of the olfactory bulb over time from its initial formation until its mature state. The olfactory bulb coordinates neuronal signaling involved in the perception of smell. It receives input from the sensory neurons and outputs to the olfactory cortex.
21773	striatal medium spiny neuron differentiation	P	The process in which a relatively unspecialized cell acquires specialized features of a medium spiny neuron residing in the striatum.
21774	retinoic acid receptor signaling pathway involved in ventral spinal cord interneuron specification	P	The series of molecular signals initiated by binding of a ligand to a retinoic acid receptor in a precursor cell in the ventral spinal cord that contributes to the commitment of the precursor cell to an interneuron fate.
21775	smoothened signaling pathway involved in ventral spinal cord interneuron specification	P	The series of molecular signals initiated by binding of a ligand to the transmembrane receptor smoothened in a precursor cell in the ventral spinal cord that contributes to the commitment of the precursor cell to an interneuron fate.
21776	smoothened signaling pathway involved in spinal cord motor neuron cell fate specification	P	The series of molecular signals initiated by binding of a ligand to the transmembrane receptor smoothened in a precursor cell in the spinal cord that contributes to the process of a precursor cell becoming capable of differentiating autonomously into a motor neuron in an environment that is neutral with respect to the developmental pathway.
21777	BMP signaling pathway involved in spinal cord association neuron specification	P	A series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, which contributes to its commitment to an association neuron fate.
21778	oligodendrocyte cell fate specification	P	The process in which a cell becomes capable of differentiating autonomously into an oligodendrocyte in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed.
21779	oligodendrocyte cell fate commitment	P	The process in which the developmental fate of a cell becomes restricted such that it will develop into an oligodendrocyte.
21780	glial cell fate specification	P	The process in which a cell becomes capable of differentiating autonomously into a glial cell in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed.
21781	glial cell fate commitment	P	The process in which the developmental fate of a cell becomes restricted such that it will develop into a glial cell.
21782	glial cell development	P	The process aimed at the progression of a glial cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.
21783	preganglionic parasympathetic fiber development	P	The process whose specific outcome is the progression of a preganglionic parasympathetic fiber over time, from its formation to the mature structure. A preganglionic parasympathetic fiber is a cholinergic axonal fiber projecting from the CNS to a parasympathetic ganglion.
21784	postganglionic parasympathetic fiber development	P	The process whose specific outcome is the progression of the postganglionic portion of the parasympathetic fiber over time, from its formation to the mature structure. The parasympathetic fiber is one of the two divisions of the vertebrate autonomic nervous system. Parasympathetic nerves emerge cranially as pre ganglionic fibers from oculomotor, facial, glossopharyngeal and vagus and from the sacral region of the spinal cord. Most neurons are cholinergic and responses are mediated by muscarinic receptors. The parasympathetic system innervates, for example: salivary glands, thoracic and abdominal viscera, bladder and genitalia.
21785	branchiomotor neuron axon guidance	P	The process in which a branchiomotor neuron growth cone is directed to a specific target site. Branchiomotor neurons are located in the hindbrain and innervate branchial arch-derived muscles that control jaw movements, facial expression, the larynx, and the pharynx.
21786	branchiomotor neuron axon guidance in neural tube	P	The process in which a branchiomotor neuron growth cone in the neural tube is directed to a specific target site in the neural tube. Branchiomotor neurons are located in the hindbrain and innervate branchial arch-derived muscles that control jaw movements, facial expression, the larynx, and the pharynx.
21787	chemorepulsion of branchiomotor neuron axon in neural tube	P	The process in which a branchiomotor neuron growth cone in the neural tube is directed to a specific target site in the neural tube in response to a repulsive chemical cue. Branchiomotor neurons are located in the hindbrain and innervate branchial arch-derived muscles that control jaw movements, facial expression, the larynx, and the pharynx.
21788	chemoattraction of branchiomotor neuron axon in neural tube	P	The process in which a branchiomotor neuron growth cone in the neural tube is directed to a specific target site in the neural tube in response to an attractive chemical cue. Branchiomotor neurons are located in the hindbrain and innervate branchial arch-derived muscles that control jaw movements, facial expression, the larynx, and the pharynx.
21789	branchiomotor neuron axon guidance in branchial arch mesenchyme	P	The process in which a branchiomotor neuron growth cone in the branchial arch mesenchyme is directed to a specific target site in the branchial arch mesenchyme. Branchiomotor neurons are located in the hindbrain and innervate branchial arch-derived muscles that control jaw movements, facial expression, the larynx, and the pharynx.
21790	chemorepulsion of branchiomotor neuron axon in branchial arch mesenchyme	P	The process in which a branchiomotor neuron growth cone in the branchial arch mesenchyme is directed to a specific target site in the branchial arch mesenchyme in response to a repulsive chemical cue. Branchiomotor neurons are located in the hindbrain and innervate branchial arch-derived muscles that control jaw movements, facial expression, the larynx, and the pharynx.
21791	chemoattraction of branchiomotor neuron axon in branchial arch mesenchyme	P	The process in which a branchiomotor neuron growth cone in the branchial arch mesenchyme is directed to a specific target site in the branchial arch mesenchyme in response to an attractive chemical cue. Branchiomotor neurons are located in the hindbrain and innervate branchial arch-derived muscles that control jaw movements, facial expression, the larynx, and the pharynx.
21792	chemoattraction of branchiomotor axon	P	The process in which a branchiomotor neuron growth cone is directed to a specific target site in response to an attractive chemical signal. Branchiomotor neurons are located in the hindbrain and innervate branchial arch-derived muscles that control jaw movements, facial expression, the larynx, and the pharynx.
21793	chemorepulsion of branchiomotor axon	P	The process in which a branchiomotor neuron growth cone is directed to a specific target site in response to a repulsive chemical cue. Branchiomotor neurons are located in the hindbrain and innervate branchial arch-derived muscles that control jaw movements, facial expression, the larynx, and the pharynx.
21794	thalamus development	P	The process in which the thalamus changes over time, from its initial formation to its mature state.
21795	cerebral cortex cell migration	P	The orderly movement of cells from one site to another in the cerebral cortex.
21796	cerebral cortex regionalization	P	The regionalization process that results in the creation of areas within the cerebral cortex that will direct the behavior of cell migration and differentiation as the cortex develops.
21797	forebrain anterior/posterior pattern specification	P	The creation of specific areas of progenitor domains along the anterior-posterior axis of the developing forebrain.
21798	forebrain dorsal/ventral pattern formation	P	The formation of specific regional progenitor domains along the dorsal-ventral axis in the developing forebrain.
21799	cerebral cortex radially oriented cell migration	P	The migration of cells in the developing cerebral cortex in which cells move from the ventricular and/or subventricular zone toward the surface of the brain.
21800	cerebral cortex tangential migration	P	The migration of cells in the cerebral cortex in which cells move orthogonally to the direction of radial migration and do not use radial glial cell processes as substrates for migration.
21801	cerebral cortex radial glia guided migration	P	The radial migration of neuronal or glial precursor cells along radial glial cells during the development of the cerebral cortex.
21802	somal translocation	P	The radial migration of cells from the ventricular zone that is independent of radial glial cells. Cells extend processes that terminate at the pial surface and follow the processes as they migrate.
21803	pial surface process extension	P	The extension of a long process to the pial surface as a cell leaves the ventricular zone.
21804	negative regulation of cell adhesion in ventricular zone	P	The process that results in the loss of attachments of a cell in the ventricular zone.
21805	cell movement involved in somal translocation	P	The movement of a cell body from the ventricular zone to the pial surface with a concomitant shortening of the process that extends to the pial surface.
21806	initiation of movement involved in cerebral cortex radial glia guided migration	P	The initial stages of cell motility involved in the glial-mediated movement of cells in the developing cerebral cortex.
21807	motogenic signaling initiating cell movement in cerebral cortex	P	The interaction of soluble factors and receptors that result in the movement of cells in the primitive cerebral cortex.
21808	cytosolic calcium signaling involved in initiation of cell movement in glial-mediated radial cell migration	P	The process that results in the fluctuations in intracellular calcium that are responsible for the initiation of movement as a component of the process of cerebral cortex glial-mediated radial migration.
21809	neurotrophic factor signaling initiating cell movement, involved in cerebral cortex radial glia guided migration	P	Signaling between members of the neurotrophin family and their receptors that result in the start of cell motility as a component of the process of cerebral cortex glial-mediated radial migration.
21810	neurotransmitter signaling initiating cell movement, involved in cerebral cortex radial glia guided migration	P	Signaling by neurotransmitters and their receptors that results in the initiation of movement of cells as a component of the process of glial-mediated radial migration.
21811	growth factor signaling initiating cell movement involved in cerebral cortex radial glia guided migration	P	Signaling between growth factors and their receptors that results in the start of cell movement, where this process is involved in glial-mediated radial migration in the cerebral cortex.
21812	neuronal-glial interaction involved in cerebral cortex radial glia guided migration	P	The changes in adhesion between neuronal cells and glial cells as a component of the process of cerebral cortex glial-mediated radial cell migration.
21813	cell-cell adhesion involved in neuronal-glial interactions involved in cerebral cortex radial glia guided migration	P	The interaction between two cells that modulates the association of a neuronal cell and a glial cell involved in glial-mediated radial cell migration in the cerebral cortex.
21814	cell motility involved in cerebral cortex radial glia guided migration	P	The movement of a cell along the process of a radial glial cell involved in cerebral cortex glial-mediated radial migration.
21815	modulation of microtubule cytoskeleton involved in cerebral cortex radial glia guided migration	P	Rearrangements of the microtubule cytoskeleton that contribute to the movement of cells along radial glial cells as a component of the process of cerebral cortex glial-mediated radial migration.
21816	extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration	P	The rearrangements of the microtubule cytoskeleton that result in the extension of a leading process, where this process is involved in the movement of cells along radial glial cells.
21817	nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration	P	The microtubule-mediated movement of the nucleus that is required for the movement of cells along radial glial fibers as a component of the process of cerebral cortex glial-mediated radial cell migration.
21818	modulation of the microfilament cytoskeleton involved in cell locomotion in cerebral cortex radial glia guided migration	P	The changes in the actin cytoskeleton that are necessary for the movement of cells along radial glial cells as a component of the process of cerebral cortex glial-mediated radial cell migration.
21819	layer formation in cerebral cortex	P	The detachment of cells from radial glial fibers at the appropriate time when they cease to migrate and form distinct layer in the cerebral cortex.
21820	extracellular matrix organization in marginal zone involved in cerebral cortex radial glia guided migration	P	The process that leads to the deposition of extracellular matrix signals in the marginal zone of the developing cerebral cortex. This extracellular matrix controls the movement of migrating cells. In mammals, the matrix is modified by Cajal-Retzius cells.
21821	negative regulation of cell-glial cell adhesion involved in cerebral cortex lamination	P	The process that results in the release of migrating cells from their interaction with radial glial cells as a component of the process of cerebral cortex glial-mediated radial cell migration.
21822	negative regulation of cell motility involved in cerebral cortex radial glia guided migration	P	The intracellular signaling pathway that results in the cessation of cell movement involved in lamination of the cerebral cortex.
21823	cerebral cortex tangential migration using cell-cell interactions	P	The process in which neurons interact with each other to promote migration along a tangential plane.
21824	cerebral cortex tangential migration using cell-axon interactions	P	The movement of cerebral cortex neuronal precursors tangentially through the cortex using interaction of the migrating cells with axons of other neurons.
21825	substrate-dependent cerebral cortex tangential migration	P	The process where neuronal precursors migrate tangentially in the cerebral cortex, primarily guided through physical cell-cell interactions.
21826	substrate-independent telencephalic tangential migration	P	The process where neuronal precursors migrate tangentially in the telencephalon, primarily guided by interactions that do not require cell-cell contact.
21827	postnatal olfactory bulb interneuron migration	P	The migration of olfactory bulb interneuron precursors in the cerebral cortex that occurs after birth.
21828	gonadotrophin-releasing hormone neuronal migration to the hypothalamus	P	The directional movement of a gonadotrophin-releasing hormone producing neuron from the nasal placode to the hypothalamus.
21829	oligodendrocyte cell migration from the subpallium to the cortex	P	The directed movement of oligodendrocytes from the subpallium to the cerebral cortex during forebrain development.
21830	interneuron migration from the subpallium to the cortex	P	The directed movement of interneurons from the subpallium to the cortex during forebrain development.
21831	embryonic olfactory bulb interneuron precursor migration	P	The directed movement of individual interneuron precursors during the embryonic development of the olfactory bulb.
21832	cell-cell adhesion involved in cerebral cortex tangential migration using cell-cell interactions	P	The attachment of cells to one another to form groups of cells involved in cerebral cortex tangential migration.
21833	cell-matrix adhesion involved in tangential migration using cell-cell interactions	P	The interaction of a cell and the extracellular matrix involved in the directed tangential movement of cells mediated by cell-cell interactions in the developing cerebral cortex.
21834	chemorepulsion involved in embryonic olfactory bulb interneuron precursor migration	P	The creation and reception of signals that guide olfactory bulb interneuron precursors down concentration gradients towards the olfactory bulb.
21835	chemoattraction involved in embryonic olfactory bulb interneuron precursor migration	P	The creation and reception of signals that result in the migration of interneuron precursors up a concentration gradient towards the olfactory bulb.
21836	chemorepulsion involved in postnatal olfactory bulb interneuron migration	P	The creation and reception of signals that repel olfactory bulb interneurons from the subventricular zone as a component process in tangential migration.
21837	motogenic signaling involved in postnatal olfactory bulb interneuron migration	P	The signaling that results in the stimulation of cell movement in the rostral migratory stream.
21838	motogenic signaling involved in interneuron migration from the subpallium to the cortex	P	The creation and reception of signals that result in the directional movement of interneuron precursors from the subpallium to the cortex.
21839	interneuron-substratum interaction involved in interneuron migration from the subpallium to the cortex	P	The process in which migrating interneurons interact with an external substratum as a component of migration from the subpallium to the cortex.
21840	directional guidance of interneurons involved in migration from the subpallium to the cortex	P	The creation and reception of signals that control the direction of migration of interneurons as a component of the process of migration from the subpallium to the cortex.
21841	chemoattraction involved in interneuron migration from the subpallium to the cortex	P	The creation and reception of signals that result in the movement of interneurons toward the signal, where this process is involved in migration from the subpallium to the cortex.
21842	chemorepulsion involved in interneuron migration from the subpallium to the cortex	P	The creation and reception of signals that result in the movement of interneurons away from the signal during migration from the subpallium to the cortex.
21843	substrate-independent telencephalic tangential interneuron migration	P	The directional movement of tangentially migrating interneurons that are not guided by attaching to extracellular substrates.
21844	interneuron sorting involved in substrate-independent cerebral cortex tangential migration	P	The establishment and response to guidance cues that distribute interneurons to different cerebral cortex structures.
21845	neurotransmitter-mediated guidance of interneurons involved in substrate-independent cerebral cortex tangential migration	P	The response of migrating interneurons to neurotransmitters that alter electrical activity in cells in calcium dependent manner.
21846	cell proliferation in forebrain	P	The creation of greater cell numbers in the forebrain due to cell division of progenitor cells.
21847	ventricular zone neuroblast division	P	The proliferation of neuroblasts in the ventricular zone of the cerebral cortex. The neuronal progenitors of these cells will migrate radially.
21848	neuroblast division in subpallium	P	The division of neuroblasts in the subpallium area of the forebrain. The interneuron precursors that these cells give rise to include GABAergic interneurons and will migrate tangentially.
21849	neuroblast division in subventricular zone	P	The division of neuroblasts in the subventricular zone of the forebrain. The interneuron precursors that these cells give rise to include adult olfactory bulb interneurons and migrate tangentially.
21850	subpallium glioblast cell division	P	The division of glioblasts in the subpallium. These cells will give rise to oligodendrocytes.
21851	neuroblast division in dorsal lateral ganglionic eminence	P	The division of neuroblasts in the dorsal region of the lateral ganglionic eminence. These cells give rise to embryonic interneuron precursors that will migrate tangentially to the olfactory bulb.
21852	pyramidal neuron migration	P	The migration of pyramidal a neuron precursor from the ventricular zone to the correct layer of the cerebral cortex.
21853	cerebral cortex GABAergic interneuron migration	P	The migration of GABAergic interneuron precursors from the subpallium to the cerebral cortex.
21854	hypothalamus development	P	The progression of the hypothalamus region of the forebrain, from its initial formation to its mature state.
21855	hypothalamus cell migration	P	The directed movement of a cell into the hypothalamus region of the forebrain.
21856	hypothalamic tangential migration using cell-axon interactions	P	The movement of a hypothalamic neuronal precursor tangentially through the forebrain using an interaction of the migrating cells with axons of other neurons.
21858	GABAergic neuron differentiation in basal ganglia	P	The process in which a neuroblast acquires the specialized structural and functional features of a GABAergic inhibitory neuron in the basal ganglia. Differentiation includes the processes involved in commitment of a neuroblast to a GABAergic neuron.
21859	pyramidal neuron differentiation	P	The process in which a neuroblast or one of its progeny commits to a pyramidal neuron fate, migrates from the ventricular zone to the appropriate layer in the cortex and develops into a mature neuron.
21860	pyramidal neuron development	P	The progression of a pyramidal neuron from its initial formation to its mature state.
21861	forebrain radial glial cell differentiation	P	The process in which neuroepithelial cells of the neural tube give rise to radial glial cells, specialized bipotential progenitors cells of the forebrain. Differentiation includes the processes involved in commitment of a cell to a specific fate.
21862	early neuron differentiation in forebrain	P	The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of neurons. Differentiation includes the processes involved in commitment of a cell to a specific fate.
21863	forebrain neuroblast differentiation	P	The process in which neuroepithelial cells in the neural tube acquire specialized structural and/or functional features of basal progenitor cells, neuroblasts that lose their contacts with the ventricular surface. Differentiation includes the processes involved in commitment of a cell to a specific fate.
21864	radial glial cell division in forebrain	P	The mitotic division of radial glial cells in the developing forebrain.
21865	symmetric radial glial cell division in forebrain	P	The mitotic division of a radial glial cell giving rise to two new radial glial cells in the forebrain.
21866	asymmetric radial glial cell division in forebrain	P	The mitotic cell division of a radial glial cell giving rise to a radial glial cell and another cell type.
21867	neuron-producing asymmetric radial glial cell division in forebrain	P	The unequal mitotic division of a radial glial cell in the forebrain that gives rise to a radial glial cell and a post-mitotic neuronal progenitor.
21868	ventricular zone cell-producing asymmetric radial glial cell division in forebrain	P	The unequal mitotic division of a forebrain radial glial cell that gives rise to a radial glial cell and a ventricular zone cell.
21869	forebrain ventricular zone progenitor cell division	P	The mitotic division of a basal progenitor giving rise to two neurons.
21870	Cajal-Retzius cell differentiation	P	The process in which a neuroblast acquires specialized structural and/or functional features of a Cajal-Retzius cell, one of a transient population of pioneering neurons in the cerebral cortex. These cells are slender bipolar cells of the developing marginal zone. One feature of these cells in mammals is that they express the Reelin gene.
21871	forebrain regionalization	P	The regionalization process resulting in the creation of areas within the forebrain that will direct the behavior of cell migration in differentiation as the forebrain develops.
21872	forebrain generation of neurons	P	The process in which nerve cells are generated in the forebrain. This includes the production of neuroblasts from and their differentiation into neurons.
21873	forebrain neuroblast division	P	The division of a neuroblast located in the forebrain. Neuroblast division gives rise to at least another neuroblast.
21874	Wnt signaling pathway involved in forebrain neuroblast division	P	The series of molecular signals initiated by binding of Wnt protein to a receptor on the surface of the target cell that contributes to the self renewal of neuroblasts in the forebrain.
21875	fibroblast growth factor receptor signaling pathway involved in forebrain neuroblast division	P	The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands that contributes to the self renewal of neuroblasts in the forebrain.
21876	Notch signaling pathway involved in forebrain neuroblast division	P	The series of molecular signals initiated by binding of an extracellular ligand to a Notch receptor on the surface of the target cell that contributes to the self renewal of neuroblasts in the forebrain.
21877	forebrain neuron fate commitment	P	The process in which the developmental fate of a cell becomes restricted such that it will develop into a neuron that resides in the forebrain.
21878	forebrain astrocyte fate commitment	P	The process in which the developmental fate of a cell becomes restricted such that it will develop into an astrocyte that resides in the forebrain.
21879	forebrain neuron differentiation	P	The process in which a relatively unspecialized cell acquires specialized features of a neuron that will reside in the forebrain.
21880	Notch signaling pathway involved in forebrain neuron fate commitment	P	The series of molecular signals initiated by binding of an extracellular ligand to a Notch receptor on the surface of the target cell that contributes to the commitment of a neuroblast to a neuronal fate. The neuron will reside in the forebrain.
21881	Wnt-activated signaling pathway involved in forebrain neuron fate commitment	P	The series of molecular signals initiated by binding of Wnt protein to a receptor on the surface of the target cell that contributes to the commitment of a neuroblast to aneuronal fate. The neuron will reside in the forebrain.
21882	regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment	P	Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that contributes to the commitment of a neuroblast to a neuronal fate. The neuron will reside in the forebrain.
21883	cell cycle arrest of committed forebrain neuronal progenitor cell	P	The process in which the cell cycle is halted during one of the normal phases (G1, S, G2, M) in a cell that has been committed to become a neuron that will reside in the forebrain.
21884	forebrain neuron development	P	The process whose specific outcome is the progression of a neuron that resides in the forebrain, from its initial commitment to its fate, to the fully functional differentiated cell.
21885	forebrain cell migration	P	The orderly movement of a cell from one site to another at least one of which is located in the forebrain.
21886	hypothalamus gonadotrophin-releasing hormone neuron differentiation	P	The process in which a relatively unspecialized cell acquires specialized features of a neuron located in the hypothalamus. These neurons release gonadotrophin-releasing hormone as a neural transmitter.
21887	hypothalamus gonadotrophin-releasing hormone neuron fate commitment	P	The process in which the developmental fate of a cell becomes restricted such that it will develop into a hypothalamus neuron that releases gonadotrophin-releasing hormone.
21888	hypothalamus gonadotrophin-releasing hormone neuron development	P	The process whose specific outcome is the progression of a hypothalamus gonadotrophin-releasing hormone neuron over time, from initial commitment of its fate, to the fully functional differentiated cell.
21889	olfactory bulb interneuron differentiation	P	The process in which a neuroblast acquires specialized features of an interneuron residing in the olfactory bulb.
21890	olfactory bulb interneuron fate commitment	P	The process in which the developmental fate of a neuroblast becomes restricted such that it will develop into an interneuron residing in the olfactory bulb.
21891	olfactory bulb interneuron development	P	The process whose specific outcome is the progression of an interneuron residing in the olfactory bulb, from its initial commitment, to the fully functional differentiated cell.
21892	cerebral cortex GABAergic interneuron differentiation	P	The process in which a relatively unspecialized cell acquires specialized features of a GABAergic interneuron residing in the cerebral cortex.
21893	cerebral cortex GABAergic interneuron fate commitment	P	The process in which the developmental fate of a neuroblast becomes restricted such that it will develop into a GABAergic interneuron residing in the cerebral cortex.
21894	cerebral cortex GABAergic interneuron development	P	The process whose specific outcome is the progression of a cerebral cortex GABAergic interneuron over time, from initial commitment to its fate, to the fully functional differentiated cell.
21895	cerebral cortex neuron differentiation	P	The process in which a relatively unspecialized cell acquires specialized features of a neuron residing in the cerebral cortex.
21896	forebrain astrocyte differentiation	P	The process in which a relatively unspecialized cell acquires the specialized features of an astrocyte residing in the forebrain. An astrocyte is the most abundant type of glial cell. Astrocytes provide support for neurons and regulate the environment in which they function.
21897	forebrain astrocyte development	P	The process aimed at the progression of an astrocyte that resides in the forebrain, from initial commitment of the cell to its fate, to the fully functional differentiated cell. An astrocyte is the most abundant type of glial cell. Astrocytes provide support for neurons and regulate the environment in which they function.
21898	commitment of multipotent stem cells to neuronal lineage in forebrain	P	The initial commitment of cells whereby the developmental fate of a cell becomes restricted such that it will develop into some type of neuron in the forebrain.
21899	fibroblast growth factor receptor signaling pathway involved in forebrain neuron fate commitment	P	The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands that contributes to the commitment of a neuroblast to a neuronal fate. The neuron will reside in the forebrain.
21900	ventricular zone cell fate commitment	P	The commitment of neuroblast to become a basal progenitor cell. Basal progenitor cells are neuronal precursor cells that are committed to becoming neurons.
21901	early neuron fate commitment in forebrain	P	The commitment of neuroepithelial cell to become a neuron that will reside in the forebrain.
21902	commitment of neuronal cell to specific neuron type in forebrain	P	The commitment of neuronal precursor cells to become specialized types of neurons in the forebrain.
21903	rostrocaudal neural tube patterning	P	The process in which the neural tube is divided into specific regions along the rostrocaudal axis.
21904	dorsal/ventral neural tube patterning	P	The process in which the neural tube is regionalized in the dorsoventral axis.
21905	forebrain-midbrain boundary formation	P	The process whose specific outcome is the creation of the forebrain-midbrain boundary.
21906	hindbrain-spinal cord boundary formation	P	The process whose specific outcome is the formation of the hindbrain-spinal cord boundary.
21907	fibroblast growth factor receptor signaling pathway involved in spinal cord anterior/posterior pattern formation	P	The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands that results in the spatial identity of regions along the anterior-posterior axis of the spinal cord.
21908	retinoic acid receptor signaling pathway involved in spinal cord anterior/posterior pattern formation	P	The series of molecular signals generated as a consequence of a retinoic acid receptor binding to one of its physiological ligands that results in the spatial identity of regions along the anterior-posterior axis of the spinal cord.
21909	regulation of transcription from RNA polymerase II promoter involved in spinal cord anterior-posterior patterning	P	Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that results in the spatial identity of regions along the anterior-posterior axis of the spinal cord.
21910	smoothened signaling pathway involved in ventral spinal cord patterning	P	The series of molecular signals generated as a consequence of activation of the transmembrane protein Smoothened that results in the spatial identity of regions along the dorsal-ventral axis of the spinal cord.
21911	retinoic acid metabolic process in spinal cord anterior-posterior patterning	P	The chemical reactions and pathways involving the synthesis and degradation of retionic acid that results in the spatial identity of regions along the anterior-posterior axis of the spinal cord.
21912	regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification	P	Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that results the commitment of a cell to become a motor neuron in the ventral spinal cord.
21913	regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification	P	Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that results in the commitment of a cell to become an interneuron in the ventral spinal cord.
21914	negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning	P	Any process that stops, prevents, or reduces the frequency, rate or extent of smoothened signaling that is involved in the patterns of cell differentiation in the ventral spinal cord.
21915	neural tube development	P	The process whose specific outcome is the progression of the neural tube over time, from its formation to the mature structure. The mature structure of the neural tube exists when the tube has been segmented into the forebrain, midbrain, hindbrain and spinal cord regions. In addition neural crest has budded away from the epithelium.
21916	inductive cell-cell signaling between paraxial mesoderm and motor neuron precursors	P	Short range signaling between cells of the paraxial mesoderm and motor neuron precursors in the spinal cord that specifies the fate of the motor column neuron precursors along the anterior-posterior axis.
21917	somatic motor neuron fate commitment	P	The commitment of unspecified motor neurons to specific motor neuron cell along the anterior-posterior axis of the spinal cord and their capacity to differentiate into specific motor neurons.
21918	regulation of transcription from RNA polymerase II promoter involved in somatic motor neuron fate commitment	P	Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that contributes to the commitment of spinal cord motor neurons to specific motor neuron types along the anterior-posterior axis.
21919	BMP signaling pathway involved in spinal cord dorsal/ventral patterning	P	A series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, which contributes to the spatial identity of regions along the dorsal-ventral axis of the spinal cord.
21920	regulation of transcription from RNA polymerase II promoter involved in spinal cord association neuron specification	P	Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that contributes to the commitment of neuronal precursors to association neurons in the dorsal spinal cord.
21921	regulation of cell proliferation in dorsal spinal cord	P	The process that modulates the frequency, rate or extent of cell proliferation in the dorsal spinal cord.
21922	Wnt signaling pathway involved in regulation of cell proliferation in dorsal spinal cord	P	The series of molecular signals initiated by binding of Wnt protein to a receptor on the surface of a cell in the dorsal spinal cord that affects the rate of its division.
21923	cell proliferation in hindbrain ventricular zone	P	The multiplication or reproduction of cells, resulting in the expansion of a cell population in the hindbrain region that is adjacent to the ventricular cavity.
21924	cell proliferation in external granule layer	P	The multiplication or reproduction of neuroblasts resulting in the expansion of a cell population in the external granule layer of the hindbrain. The external granule layer is the layer that originates from the rostral half of the rhombic lip in the first rhombomere.
21925	cerebellar Purkinje cell precursor proliferation	P	The multiplication or reproduction of neuroblasts that will give rise to Purkinje cells. A Purkinje cell is an inhibitory GABAergic neuron found in the cerebellar cortex that projects to the deep cerebellar nuclei and brain stem.
21926	Golgi cell precursor proliferation	P	The multiplication or reproduction of neuroblasts that will give rise to Golgi cells. A Golgi cell is an inhibitory GABAergic interneuron found in the cerebellar cortex.
21927	deep nuclear neuron precursor proliferation	P	The multiplication or reproduction of neuroblasts that will give rise to deep nuclear neurons.
21928	basket cell precursor proliferation	P	The multiplication or reproduction of neuroblasts that will give rise to basket cells. A cerebellar basket cell is an inhibitory GABAergic interneuron found in the cerebellar cortex.
21929	stellate cell precursor proliferation	P	The multiplication or reproduction of neuroblasts that will give rise to stellate cells. A cerebellar stellate cell is an inhibitory GABAergic interneuron found in the cerebellar cortex.
21930	cerebellar granule cell precursor proliferation	P	The multiplication or reproduction of neuroblasts that will give rise to granule cells. A granule cell is a glutamatergic interneuron found in the cerebellar cortex.
21931	rostral hindbrain neuronal precursor cell proliferation	P	The multiplication or reproduction of neuroblasts that will give rise to neurons of the lateral pontine nucleus and the locus ceruleus.
21932	hindbrain radial glia guided cell migration	P	The radially directed movement of a cell along radial glial cells in the hindbrain. Radial migration refers to a directed movement from the internal ventricular area to the outer surface of the hindbrain.
21933	radial glia guided migration of cerebellar granule cell	P	The inward migration of postmitotic granule cells along a radial glial cell from the external granule layer to the internal granule cell layer.
21934	hindbrain tangential cell migration	P	The migration of a cell in the hindbrain in which cells move orthogonal to the direction of radial migration.
21935	cerebellar granule cell precursor tangential migration	P	The early migration of granule cell precursors in which cells move orthogonal to the direction of radial migration and ultimately cover the superficial zone of the cerebellar primordium.
21936	regulation of cerebellar granule cell precursor proliferation	P	The process that modulates the frequency, rate or extent of granule cell precursor proliferation.
21937	cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation	P	The process that mediates the transfer of information from Purkinje cells to granule cell precursors resulting in an increase in rate of granule cell precursor cell proliferation.
21938	smoothened signaling pathway involved in regulation of cerebellar granule cell precursor cell proliferation	P	The series of molecular signals generated as a consequence of activation of the transmembrane protein Smoothened in cerebellar granule cells that contributes to the regulation of proliferation of the cells.
21939	extracellular matrix-granule cell signaling involved in regulation of granule cell precursor proliferation	P	The process that mediates the transfer of information from the extracellular matrix to granule cell precursors resulting in a decrease in rate of granule cell precursor cell proliferation.
21940	positive regulation of cerebellar granule cell precursor proliferation	P	The process that activates or increases the rate or extent of granule cell precursor proliferation.
21941	negative regulation of cerebellar granule cell precursor proliferation	P	The process that stops, prevents or reduces the rate or extent of granule cell precursor proliferation.
21942	radial glia guided migration of Purkinje cell	P	The migration of postmitotic a Purkinje cell along radial glial cells from the ventricular zone to the Purkinje cell layer.
21943	formation of radial glial scaffolds	P	The formation of scaffolds from a radial glial cell. The scaffolds are used as a substrate for the radial migration of cells.
21944	neuronal-glial interaction involved in hindbrain glial-mediated radial cell migration	P	The changes in adhesion between a neuronal cell and a glial cell as a component of the process of hindbrain glial-mediated radial cell migration.
21945	positive regulation of cerebellar granule cell migration by calcium	P	The process that increases the extent of granule cell motility using intracellular calcium signaling mechanisms during radial migration.
21946	deep nuclear neuron cell migration	P	The directed movement of a deep nuclear neuron from the ventricular zone to the deep hindbrain nuclei.
21947	outward migration of deep nuclear neurons	P	The directed movement of a deep nuclear neuron from their ventrolateral origin to a rostrodorsal region of the cerebellar plate.
21948	inward migration of deep nuclear neurons	P	The directed movement of a deep nuclear neuron from the rostrodorsal region of the cerebellar plate to their final more ventral position.
21949	brainstem precerebellar neuron precursor migration	P	The early migration of a precerebellar neuronal precursor in which a cell move from the rhombic lip, orthogonal to the direction of radial migration and ultimately reside in the brainstem.
21950	chemorepulsion involved in precerebellar neuron migration	P	The creation and reception of signals that repel a precerebellar neuron as a component of the process of tangential migration.
21951	chemoattraction involved in precerebellar neuron migration	P	The creation and reception of signals that guide a precerebellar neuron towards their signals, where this process is involved in tangential migration.
21952	central nervous system projection neuron axonogenesis	P	Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body towards target cells in a different central nervous system region.
21953	central nervous system neuron differentiation	P	The process in which a relatively unspecialized cell acquires specialized features of a neuron whose cell body resides in the central nervous system.
21954	central nervous system neuron development	P	The process whose specific outcome is the progression of a neuron whose cell body is located in the central nervous system, from initial commitment of the cell to a neuronal fate, to the fully functional differentiated neuron.
21955	central nervous system neuron axonogenesis	P	Generation of a long process from a neuron whose cell body resides in the central nervous system. The process carries efferent (outgoing) action potentials from the cell body towards target cells.
21956	central nervous system interneuron axonogenesis	P	Generation of a long process that carries efferent (outgoing) action potentials from the cell body towards target cells from a neuron located in the central nervous system whose axons remain within a single brain region.
21957	corticospinal tract morphogenesis	P	Generation of a long process of a pyramidal cell, that carries efferent (outgoing) action potentials from the cell body in cerebral cortex layer V towards target cells in the gray matter of the spinal cord. This axonal process is a member of those that make up the corticospinal tract.
21958	gracilis tract morphogenesis	P	Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the dorsal root ganglion towards target cells in the medulla. This axonal process is a member of those that make up the gracilis tract, a group of axons that are from neurons involved in proprioception from the lower trunk and lower limb.
21959	cuneatus tract morphogenesis	P	Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the dorsal root ganglion towards target cells in the medulla. This axonal process is a member of those that make up the cuneatus tract, a group of axons that are from neurons involved in proprioception from the upper trunk and upper limb.
21960	anterior commissure morphogenesis	P	Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in one half of the cerebral cortex towards target cells in the contralateral half. This axonal process is a member of those that make up the anterior commissure, a small midline fiber tract that lies at the anterior end of the corpus callosum.
21961	posterior commissure morphogenesis	P	Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the midbrain towards target cells in the diencephalon.
21962	vestibulospinal tract morphogenesis	P	Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the vestibular nucleus of the pons towards target cells in the spinal cord.
21963	spinothalamic tract morphogenesis	P	Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the spinal cord towards target cells in the thalamus. This axonal process is a member of those that make up the spinothalamic tract, one of the major routes of nociceptive signaling.
21964	rubrospinal tract morphogenesis	P	Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the red nucleus of the midbrain towards target cells in the spinal cord.
21965	spinal cord ventral commissure morphogenesis	P	The process in which the anatomical structures of the spinal cord ventral commissure are generated and organized.
21966	corticospinal neuron axon guidance	P	The process in which the migration of an axon growth cone of a neuron that is part of the corticospinal tract is directed from the cerebral cortex layer V to the spinal cord dorsal funiculus in response to a combination of attractive and repulsive cues.
21967	corticospinal neuron axon guidance through the cerebral cortex	P	The process in which the migration of an axon growth cone of a pyramidal cell that is part of the corticospinal tract is directed from its cell body in layer V through the cerebral cortex in response to a combination of attractive and repulsive cues.
21968	corticospinal neuron axon guidance through the internal capsule	P	The process in which the migration of an axon growth cone of a pyramidal cell that is part of the corticospinal tract is directed after exiting the cerebral cortex through the internal capsule in response to a combination of attractive and repulsive cues.
21969	corticospinal neuron axon guidance through the cerebral peduncle	P	The process in which the migration of an axon growth cone of a pyramidal cell that is part of the corticospinal tract is directed after exiting the internal capsule through the cerebral peduncle in response to a combination of attractive and repulsive cues.
21970	corticospinal neuron axon guidance through the basilar pons	P	The process in which the migration of an axon growth cone of a pyramidal cell that is part of the corticospinal tract is directed after exiting the cerebral peduncle through the basilar pons in response to a combination of attractive and repulsive cues.
21971	corticospinal neuron axon guidance through the medullary pyramid	P	The process in which the migration of an axon growth cone of a pyramidal cell that is part of the corticospinal tract is directed after exiting the basilar pons through the medullary pyramid in response to a combination of attractive and repulsive cues.
21972	corticospinal neuron axon guidance through spinal cord	P	The process in which the migration of an axon growth cone of a pyramidal cell that is part of the corticospinal tract is directed after decussation through the spinal cord in response to a combination of attractive and repulsive cues.
21973	corticospinal neuron axon decussation	P	The process in which the migration of an axon growth cone of a pyramidal cell that is part of the corticospinal tract is directed to cross the midline to the contralateral side.
21974	trigeminothalamic tract morphogenesis	P	Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in spinal cord towards target cells in the thalamus. This axonal process is a member of those that make up the trigeminothalamic tract, one of the major routes of nociceptive and temperature signaling from the face.
21975	pons reticulospinal tract morphogenesis	P	Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the pons towards target cells in the spinal cord.
21976	medulla reticulospinal tract morphogenesis	P	Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the medulla towards target cells in the spinal cord.
21977	tectospinal tract morphogenesis	P	Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the superior colliculus of the midbrain towards target cells in the ventral spinal cord.
21978	telencephalon regionalization	P	The regionalization process that creates areas within the forebrain that will direct the behavior of cell migration in differentiation as the telencephalon develops.
21979	hypothalamus cell differentiation	P	The differentiation of cells that will contribute to the structure and function of the hypothalamus.
21980	subpallium cell migration	P	The orderly movement of cells from one site to another in the subpallium.
21981	subpallium radially oriented migration	P	The migration of cells in the developing subpallium in which cells move from the ventricular and/or subventricular zone toward the surface of the brain.
21982	pineal gland development	P	The progression of the pineal gland over time from its initial formation until its mature state. The pineal gland is an endocrine gland that secretes melatonin and is involved in circadian rhythms.
21983	pituitary gland development	P	The progression of the pituitary gland over time from its initial formation until its mature state. The pituitary gland is an endocrine gland that secretes hormones that regulate many other glands.
21984	adenohypophysis development	P	The progression of the adenohypophysis over time from its initial formation until its mature state. The adenohypophysis is the anterior part of the pituitary. It secretes a variety of hormones and its function is regulated by the hypothalamus.
21985	neurohypophysis development	P	The progression of the neurohypophysis over time from its initial formation until its mature state. The neurohypophysis is the part of the pituitary gland that secretes hormones involved in blood pressure regulation.
21986	habenula development	P	The progression of the habenula over time from its initial formation until its mature state. The habenula is the group of nuclei that makes up the stalk of the pineal gland.
21987	cerebral cortex development	P	The progression of the cerebral cortex over time from its initial formation until its mature state. The cerebral cortex is the outer layered region of the telencephalon.
21988	olfactory lobe development	P	The progression of the olfactory lobe over time from its initial formation until its mature state. The olfactory lobe is the area of the brain that process the neural inputs for the sense of smell.
21989	olfactory cortex development	P	The progression of the olfactory cortex over time from its initial formation until its mature state. The olfactory cortex is involved in the perception of smell. It receives input from the olfactory bulb and is responsible for the identification of odors.
21990	neural plate formation	P	The formation of the flat, thickened layer of ectodermal cells known as the neural plate. The underlying dorsal mesoderm signals the ectodermal cells above it to elongate into columnar neural plate cells. The neural plate subsequently develops into the neural tube, which gives rise to the central nervous system.
21991	neural plate thickening	P	The process of apical-basal elongation of individual ectodermal cells during the formation of the neural placode.
21992	cell proliferation involved in neural plate elongation	P	The process of expansion of cell numbers in the neural plate due to cell division of progenitor cells preferentially in the rostrocaudal direction, resulting in the elongation of the tissue.
21993	initiation of neural tube closure	P	The process in which closure points are established at multiple points and along the neural rostrocaudal axis.
21994	progression of neural tube closure	P	The process in which the neural folds are fused extending from the initial closure points.
21995	neuropore closure	P	The process of joining together the neural folds at either end of the neural tube.
21996	lamina terminalis formation	P	The process in which the anterior-most portion of the neural axis is formed by closure of the anterior neuropore.
21997	neural plate axis specification	P	The pattern specification process in which the axes of the nervous system are established.
21998	neural plate mediolateral regionalization	P	The process that regulates the coordinated growth and differentiation that establishes the non-random mediolateral spatial arrangement of the neural plate.
21999	neural plate anterior/posterior regionalization	P	The process that regulates the coordinated growth and differentiation that establishes the non-random anterior-posterior spatial arrangement of the neural plate.
22000	forebrain induction by the anterior neural ridge	P	The close range interaction of the anterior neural ridge to the caudal region of the neural plate that specifies the forebrain fate.
22001	negative regulation of anterior neural cell fate commitment of the neural plate	P	Any process that stops, prevents or reduces the frequency or rate at which a cell adopts an anterior neural cell fate.
22002	negative regulation of anterior neural cell fate commitment of the neural plate by Wnt signaling pathway	P	The series of molecular signals that stops, prevents or reduces the frequency or rate at which a cell adopts an anterior neural cell fate, initiated by binding of Wnt protein to a receptor on the surface of the target cell.
22003	negative regulation of anterior neural cell fate commitment of the neural plate by fibroblast growth factor receptor signaling pathway	P	The series of molecular signals that stops, prevents or reduces the frequency or rate at which cell adopts an anterior neural cell fate, generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands.
22004	midbrain-hindbrain boundary maturation during brain development	P	A developmental process occurring after the brain has been specified along the neural axis that is required for the midbrain-hindbrain boundary to attain its fully functional state. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. An organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate.
22005	midbrain-hindbrain boundary maturation during neural plate development	P	A developmental process occurring before the brain has been specified along the neural axis that is required for the midbrain-hindbrain boundary to attain its fully functional state. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages. An organizing center at the boundary patterns the midbrain and hindbrain primordia of the neural plate.
22006	zona limitans intrathalamica formation	P	The formation of the narrow stripe of cells that lies between the prospective dorsal and ventral thalami. This boundary contains signals that pattern the prethalamic and thalamic territories of the future mid-diencephalon.
22007	convergent extension involved in neural plate elongation	P	The process of directed cell movement in the neural plate resulting in tissue elongation via intercalation of adjacent cells in an epithelial sheet at the midline, leading to narrowing and lengthening of the neural plate.
22008	neurogenesis	P	Generation of cells within the nervous system.
22009	central nervous system vasculogenesis	P	The differentiation of endothelial cells from progenitor cells during blood vessel development, and the de novo formation of blood vessels and tubes in the central nervous system. The capillary endothelial cells in the brain are specialized to form the blood-brain barrier.
22010	central nervous system myelination	P	The process in which neuronal axons and dendrites become coated with a segmented lipid-rich sheath (myelin) to enable faster and more energetically efficient conduction of electrical impulses. The sheath is formed by the cell membranes of oligodendrocytes in the central nervous system. Adjacent myelin segments are separated by a non-myelinated stretch of axon called a node of Ranvier.
22011	myelination in peripheral nervous system	P	The process in which neuronal axons and dendrites become coated with a segmented lipid-rich sheath (myelin) to enable faster and more energetically efficient conduction of electrical impulses. The sheath is formed by the cell membranes of Schwann cells in the peripheral nervous system. Adjacent myelin segments are separated by a non-myelinated stretch of axon called a node of Ranvier.
22012	subpallium cell proliferation in forebrain	P	The multiplication or reproduction of subpallium cells in the forebrain, resulting in the expansion of a cell population.
22013	pallium cell proliferation in forebrain	P	The multiplication or reproduction of pallium cells in the forebrain, resulting in the expansion of the cell population.
22014	radial glial cell division in subpallium	P	The division of a radial glial cell in the subpallium. A radial glial cell is a precursor cell that gives rise to neurons and astrocytes.
22015	radial glial cell division in pallium	P	The division of a radial glial cell in the pallium. A radial glial cell is a precursor cell that gives rise to neurons and astrocytes.
22016	pallium glioblast division	P	The division of a glioblast in the pallium. A glioblast is a dividing precursor cell that gives rise to glial cells.
22017	neuroblast division in pallium	P	The division of neuroblasts in the pallium. Neuroblasts are precursor cells that give rise to neurons.
22018	lateral ganglionic eminence cell proliferation	P	The multiplication or reproduction of lateral ganglionic eminence cells, resulting in the expansion of the cell population.
22019	dorsal lateral ganglionic eminence cell proliferation	P	The multiplication or reproduction of dorsal lateral ganglionic eminence cells, resulting in the expansion of the cell population.
22020	medial ganglionic eminence cell proliferation	P	The multiplication or reproduction of medial ganglionic eminence cells, resulting in the expansion of a cell population.
22021	caudal ganglionic eminence cell proliferation	P	The multiplication or reproduction of caudal ganglionic eminence cells, resulting in the expansion of a cell population.
22022	septal cell proliferation	P	The multiplication or reproduction of septal cells, resulting in the expansion of a cell population.
22023	radial glial cell fate commitment in forebrain	P	The process in which the developmental fate of a cell becomes restricted such that it will develop into a radial glial cell in the forebrain.
22024	BMP signaling pathway involved in forebrain neuron fate commitment	P	A series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, which contributes to the commitment of a neuroblast to a neuronal fate. The neuron will reside in the forebrain.
22025	leukemia inhibitory factor signaling pathway involved in forebrain neuron fate commitment	P	Any series of molecular signals initiated by the binding of leukemia inhibitory factor to a receptor on the surface of the target cell, that contributes to the commitment of a neuroblast to a neuronal fate. The neuron will reside in the forebrain.
22026	epidermal growth factor signaling pathway involved in forebrain neuron fate commitment	P	The series of molecular signals generated as a consequence of a epidermal growth factor receptor binding to one of its physiological ligands that contributes to the commitment of a neuroblast to a neuronal fate. The neuron will reside in the forebrain.
22027	interkinetic nuclear migration	P	The movement of the nucleus of the ventricular zone cell between the apical and the basal zone surfaces. Mitosis occurs when the nucleus is near the apical surface, that is, the lumen of the ventricle.
22028	tangential migration from the subventricular zone to the olfactory bulb	P	The migration of cells in the telencephalon from the subventricular zone to the olfactory bulb in which cells move orthogonally to the direction of radial migration and do not use radial glial cell processes as substrates for migration.
22029	telencephalon cell migration	P	The orderly movement of a cell from one site to another at least one of which is located in the telencephalon.
22030	telencephalon glial cell migration	P	The orderly movement of glial cells through the telencephalon.
22031	telencephalon astrocyte cell migration	P	The orderly movement of an astrocyte cell through the telencephalon.
22032	telencephalon oligodendrocyte cell migration	P	The multiplication or reproduction of telencephalon oligodendrocyte cells, resulting in the expansion of a cell population.
22033	telencephalon microglial cell migration	P	The orderly movement of microglial cells through the telencephalon.
22034	rhombomere cell proliferation	P	The multiplication or reproduction of rhombomere cells, resulting in the expansion of the cell population.
22035	rhombomere cell migration	P	The movement of a cell within a rhombomere. This process is known to occur as an early step in the generation of anatomical structure from a rhombomere.
22036	rhombomere cell differentiation	P	The process in which a relatively unspecialized cell acquires specialized features of a rhombomere cell.
22037	metencephalon development	P	The process whose specific outcome is the progression of the metencephalon over time, from its formation to the mature structure.
22038	corpus callosum development	P	The process whose specific outcome is the progression of the corpus callosum over time, from its formation to the mature structure. The corpus callosum is a thick bundle of nerve fibers comprising a commissural plate connecting the two cerebral hemispheres. It consists of contralateral axon projections that provide communication between the right and left cerebral hemispheres.
22400	regulation of rhodopsin mediated signaling pathway	P	Any process that modulates the frequency, rate or extent of rhodopsin-mediated signaling.
22401	negative adaptation of signaling pathway	P	The negative regulation of a signal transduction pathway in response to a stimulus upon prolonged exposure to that stimulus.
22402	cell cycle process	P	The cellular process that ensures successive accurate and complete genome replication and chromosome segregation.
22403	cell cycle phase	P	One of the distinct periods or stages into which the cell cycle is divided. Each phase is characterized by the occurrence of specific biochemical and morphological events.
22404	molting cycle process	P	A multicellular organismal process involved in the periodic casting off and regeneration of an outer covering of cuticle, feathers, hair, horns, skin.
22405	hair cycle process	P	A multicellular organismal process involved in the cyclical phases of growth (anagen), regression (catagen), quiescence (telogen), and shedding (exogen) in the life of a hair; one of the collection or mass of filaments growing from the skin of an animal, and forming a covering for a part of the head or for any part or the whole of the body.
22406	membrane docking	P	The initial attachment of a membrane or protein to a target membrane. Docking requires only that the proteins come close enough to interact and adhere.
22407	regulation of cell-cell adhesion	P	Any process that modulates the frequency, rate or extent of attachment of a cell to another cell.
22408	negative regulation of cell-cell adhesion	P	Any process that stops, prevents or reduces the rate or extent of cell adhesion to another cell.
22409	positive regulation of cell-cell adhesion	P	Any process that activates or increases the rate or extent of cell adhesion to another cell.
22410	circadian sleep/wake cycle process	P	A behavioral process involved in the cycle from wakefulness through an orderly succession of sleep states and stages that occurs on an approximately 24 hour rhythm.
22411	cellular component disassembly	P	A cellular process that results in the breakdown of a cellular component.
22412	cellular process involved in reproduction in multicellular organism	P	A process, occurring at the cellular level, that is involved in the reproductive function of a multicellular organism.
22413	reproductive process in single-celled organism	P	A process, occurring at the cellular level, that is involved in the reproductive function of a single-celled organism.
22414	reproductive process	P	A biological process that directly contributes to the process of producing new individuals by one or two organisms. The new individuals inherit some proportion of their genetic material from the parent or parents.
22416	chaeta development	P	The process whose specific outcome is the progression of a chaeta over time, from its formation to the mature structure. A chaeta is a sensory multicellular cuticular outgrowth of a specifically differentiated cell.
22417	protein maturation by protein folding	P	The process of assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure that results in the attainment of the full functional capacity of a protein.
22600	digestive system process	P	A physical, chemical, or biochemical process carried out by living organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism.
22601	menstrual cycle phase	P	The progression of physiological phases, occurring in the endometrium during the menstrual cycle that recur at regular intervals during the reproductive years. The menstrual cycle is an ovulation cycle where the endometrium is shed if pregnancy does not occur.
22602	ovulation cycle process	P	A process involved in the sexual cycle seen in females, often with physiologic changes in the endometrium that recur at regular intervals during the reproductive years.
22603	regulation of anatomical structure morphogenesis	P	Any process that modulates the frequency, rate or extent of anatomical structure morphogenesis.
22604	regulation of cell morphogenesis	P	Any process that modulates the frequency, rate or extent of cell morphogenesis. Cell morphogenesis is the developmental process in which the shape of a cell is generated and organized.
22605	oogenesis stage	P	A reproductive process that is a step in the formation and maturation of an ovum or female gamete from a primordial female germ cell.
22606	establishment of proximal/distal cell polarity	P	The specification and formation of the polarity of a cell along its proximal/distal axis.
22607	cellular component assembly	P	The aggregation, arrangement and bonding together of a cellular component.
22608	multicellular organism adhesion	P	The attachment of a multicellular organism to a substrate or other organism.
22609	multicellular organism adhesion to substrate	P	The attachment of a multicellular organism to a surface or material.
22610	biological adhesion	P	The attachment of a cell or organism to a substrate, another cell, or other organism. Biological adhesion includes intracellular attachment between membrane regions.
22611	dormancy process	P	A developmental process in which dormancy (sometimes called a dormant state) is induced, maintained or broken. Dormancy is a suspension of most physiological activity and growth that can be reactivated.
22612	gland morphogenesis	P	The process in which the anatomical structures of a gland are generated and organized.
22613	ribonucleoprotein complex biogenesis	P	A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a complex containing RNA and proteins. Includes the biosynthesis of the constituent RNA and protein molecules, and those macromolecular modifications that are involved in synthesis or assembly of the ribonucleoprotein complex.
22614	membrane to membrane docking	P	The initial attachment of a membrane to a target membrane, mediated by proteins protruding from the two membranes. Docking requires only that the membranes come close enough for the proteins to interact and adhere.
22615	protein to membrane docking	P	The initial attachment of a protein to a target membrane, mediated by a proteins protruding from the target membrane. Docking requires only that the proteins come close enough to interact and adhere.
22616	DNA strand elongation	P	The DNA metabolic process in which a DNA strand is synthesized by adding nucleotides to the 3' end of an existing DNA stand.
22617	extracellular matrix disassembly	P	A process that results in the breakdown of the extracellular matrix.
22618	ribonucleoprotein complex assembly	P	The aggregation, arrangement and bonding together of proteins and RNA molecules to form a ribonucleoprotein complex.
22619	generative cell differentiation	P	The process in which a relatively unspecialized cell acquires specialized features of a generative cell. The generative cell gives rise to the sperm cells in the male gametophyte.
22620	vegetative cell differentiation	P	The process in which a relatively unspecialized cell acquires specialized features of a vegetative cell. The vegetative cell is gives rise to the pollen tube.
22622	root system development	P	The process whose specific outcome is the progression of the root system over time, from its formation to the mature structure.
22623	proteasome-activating nucleotidase complex	C	A homohexameric complex that recognizes and unfolds core proteasome substrate proteins, and translocates them to the core complex in an ATP dependent manner.
22624	proteasome accessory complex	C	A protein complex, that caps one or both ends of the proteasome core complex and regulates entry into, or exit from, the proteasome core complex.
22625	cytosolic large ribosomal subunit	C	The large subunit of a ribosome located in the cytosol.
22626	cytosolic ribosome	C	A ribosome located in the cytosol.
22627	cytosolic small ribosomal subunit	C	The small subunit of a ribosome located in the cytosol.
22628	chloroplast large ribosomal subunit	C	The large subunit of a ribosome contained within a chloroplast.
22629	chloroplast small ribosomal subunit	C	The small subunit of a ribosome contained within a chloroplast.
22803	passive transmembrane transporter activity	F	Enables the transfer of a solute from one side of the membrane to the other, down the solute's concentration gradient.
22804	active transmembrane transporter activity	F	Catalysis of the transfer of a specific substance or related group of substances from one side of a membrane to the other, up the solute's concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction.
22809	mobile ion carrier activity	F	This is a type of carrier produced by bacteria. It enables passive transport by shielding the ion that is being transported from the lipid membrane. It carries an ion across the membrane by enclosing the ion and travelling across the membrane. It does not form a fully open pore across the membrane.
22810	membrane potential driven uniporter activity	F	Enables the active transport of a solute across a membrane by a mechanism involving conformational change, where energy for active transport is derived from membrane potential if the solute is charged.
22814	facilitated diffusion	F	Catalysis of the transfer of a single solute from one side of the membrane to the other by a mechanism involving conformational change, either by facilitated diffusion or in a membrane potential dependent process if the solute is charged.
22818	sodium ion uniporter activity	F	Catalysis of the active transport of a sodium ion across a membrane by a mechanism involving conformational change, where energy for active transport is derived from membrane potential if the solute is charged.
22819	potassium ion uniporter activity	F	Catalysis of the active transport of a potassium ion across a membrane by a mechanism involving conformational change, where energy for active transport is derived from membrane potential if the solute is charged.
22820	potassium ion symporter activity	F	Catalysis of the active transport of a potassium ion across a membrane by a mechanism whereby two or more species are transported together in the same direction in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy.
22821	potassium ion antiporter activity	F	Catalysis of the active transport of a potassium ion across a membrane by a mechanism whereby two or more species are transported in opposite directions in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy.
22824	transmitter-gated ion channel activity	F	Enables the transmembrane transfer of an ion by a channel that opens when a specific neurotransmitter has been bound by the channel complex or one of its constituent parts.
22828	phosphorylation-gated channel activity	F	Enables the transmembrane transfer of a solute by a channel that opens in response to phosphorylation of one of its constituent parts.
22829	wide pore channel activity	F	Enables the transport of a solute across a membrane via a large pore, un-gated channel. Examples include gap junctions, which transport substances from one cell to another; and porins which transport substances in and out of bacteria, mitochondria and chloroplasts.
22831	narrow pore, gated channel activity	F	Enables the transport of a solute across a membrane via a narrow pore channel that opens in response to a particular stimulus.
22832	voltage-gated channel activity	F	Enables the transmembrane transfer of a solute by a channel whose open state is dependent on the voltage across the membrane in which it is embedded.
22833	mechanically gated channel activity	F	Enables the transmembrane transfer of a solute by a channel that opens in response to a mechanical stress.
22834	ligand-gated channel activity	F	Enables the transmembrane transfer of a solute by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts.
22835	transmitter-gated channel activity	F	Enables the transmembrane transfer of a solute by a channel that opens when a specific neurotransmitter has been bound by the channel complex or one of its constituent parts.
22836	gated channel activity	F	Enables the transmembrane transfer of a solute by a channel that opens in response to a specific stimulus.
22838	substrate-specific channel activity	F	Enables the energy-independent facilitated diffusion, mediated by passage of a specific solute through a transmembrane aqueous pore or channel. Stereospecificity is not exhibited but this transport may be specific for a particular molecular species or class of molecules.
22839	ion gated channel activity	F	Enables the transmembrane transfer of a solute by a channel that opens in response to a specific ion stimulus.
22840	leak channel activity	F	Enables the transport of a solute across a membrane via a narrow pore channel that is open even in an unstimulated or 'resting' state.
22841	potassium ion leak channel activity	F	Enables the transport of a potassium ion across a membrane via a narrow pore channel that is open even in an unstimulated or 'resting' state.
22842	narrow pore channel activity	F	Enables the transport of a solute across a membrane via a narrow pore channel that may be gated or ungated.
22843	voltage-gated cation channel activity	F	Enables the transmembrane transfer of a cation by a voltage-gated channel. A cation is a positively charged ion. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.
22848	acetylcholine-gated cation-selective channel activity	F	Selectively enables the transmembrane transfer of a cation by a channel that opens upon binding acetylcholine.
22849	glutamate-gated calcium ion channel activity	F	Enables the transmembrane transfer of a calcium ion by a channel that opens when glutamate has been bound by the channel complex or one of its constituent parts.
22850	serotonin-gated cation-selective channel activity	F	Enables the transmembrane transfer of a cation by a channel that opens when serotonin has been bound by the channel complex or one of its constituent parts.
22851	GABA-gated chloride ion channel activity	F	Enables the transmembrane transfer of a chloride ion by a channel that opens when GABA has been bound by the channel complex or one of its constituent parts.
22852	glycine-gated chloride ion channel activity	F	Enables the transmembrane transfer of a chloride ion by a channel that opens when glycine has been bound by the channel complex or one of its constituent parts.
22853	active ion transmembrane transporter activity	F	Catalysis of the transfer of an ion from one side of a membrane to the other up the solute's concentration gradient. This is carried out by binding the solute and undergoing a series of conformational changes. Transport works equally well in either direction.
22855	protein-N(PI)-phosphohistidine-glucose phosphotransferase system transporter activity	F	Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + glucose(out) = protein histidine + glucose phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.
22856	protein-N(PI)-phosphohistidine-sorbitol phosphotransferase system transporter activity	F	Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + sorbitol(out) = protein histidine + sorbitol phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.
22857	transmembrane transporter activity	F	Enables the transfer of a substance from one side of a membrane to the other.
22858	alanine transmembrane transporter activity	F	Enables the transfer of alanine from one side of a membrane to the other. Alanine is 2-aminopropanoic acid.
22859	dephosphorylation-gated channel activity	F	Enables the transmembrane transfer of a solute by a channel that opens in response to dephosphorylation of one of its constituent parts.
22865	transmembrane electron transfer carrier	F	Enables electron flow across a biological membrane, from donors localized on one side of the membrane to acceptors localized on the other side. These systems contribute to or subtract from the membrane potential, depending on the direction of electron flow. They are therefore important to cellular energetics.
22866	transmembrane 1-electron transfer carrier	F	Enables transfer of one electron across a membrane.
22867	transmembrane 2-electron transfer carrier	F	Enables transfer of two electrons across a membrane.
22869	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity	F	Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + lactose(out) = protein histidine + lactose phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.
22870	protein-N(PI)-phosphohistidine-mannose phosphotransferase system transporter activity	F	Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + mannose(out) = protein histidine + mannose phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.
22871	protein-N(PI)-phosphohistidine-sorbose phosphotransferase system transporter activity	F	Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + sorbose(out) = protein histidine + sorbose phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.
22872	protein-N(PI)-phosphohistidine-mannitol phosphotransferase system transmembrane transporter activity	F	Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + mannitol(out) = protein histidine + mannitol phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.
22873	protein-N(PI)-phosphohistidine-maltose phosphotransferase system transporter activity	F	Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + maltose(out) = protein histidine + maltose phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.
22874	protein-N(PI)-phosphohistidine-cellobiose phosphotransferase system transporter activity	F	Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + cellobiose(out) = protein histidine + cellobiose phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.
22875	protein-N(PI)-phosphohistidine-galactitol phosphotransferase system transmembrane transporter activity	F	Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + galactitol(out) = protein histidine + galactitol phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.
22876	protein-N(PI)-phosphohistidine-galactosamine phosphotransferase system transporter activity	F	Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + galactosamine(out) = protein histidine + galactosamine phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.
22877	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity	F	Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + fructose(out) = protein histidine + fructose phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.
22878	protein-N(PI)-phosphohistidine-sucrose phosphotransferase system transporter activity	F	Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + sucrose(out) = protein histidine + sucrose phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.
22879	protein-N(PI)-phosphohistidine-trehalose phosphotransferase system transporter activity	F	Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + trehalose(out) = protein histidine + trehalose phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.
22880	protein-N(PI)-phosphohistidine-N-acetylglucosamine phosphotransferase system transporter activity	F	Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + N-acetylglucosamine(out) = protein histidine + N-acetylglucosamine phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.
22881	protein-N(PI)-phosphohistidine-N-acetylgalactosamine phosphotransferase system transporter activity	F	Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + N-acetylgalactosamine(out) = protein histidine + N-acetylgalactosamine phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.
22882	protein-N(PI)-phosphohistidine-beta-glucoside phosphotransferase system transporter activity	F	Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + beta-glucoside(out) = protein histidine + beta-glucoside phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.
22883	zinc efflux transmembrane transporter activity	F	Catalysis of the transfer of a zinc ion or zinc ions from the inside of the cell to the outside of the cell across a membrane.
22884	macromolecule transmembrane transporter activity	F	Enables the transfer of a macromolecule from one side of the membrane to the other.
22885	bacteriocin transmembrane transporter activity	F	Enables the transfer of a bacteriocin from one side of the membrane to the other.
22886	channel-forming ionophore activity	F	Enables transport of a solute across a membrane. This kind of transporter interacts much more weakly with the solute than the carrier does. It is an aqueous pore that extends across the membrane. It may change from closed to open and back. It transports faster than a carrier. It is always passive.
22889	serine transmembrane transporter activity	F	Enables the transfer of serine from one side of a membrane to the other. Serine is 2-amino-3-hydroxypropanoic acid.
22890	inorganic cation transmembrane transporter activity	F	Enables the transfer of inorganic cations from one side of a membrane to the other. Inorganic cations are atoms or small molecules with a positive charge that do not contain carbon in covalent linkage.
22891	substrate-specific transmembrane transporter activity	F	Enables the transfer of a specific substance or group of related substances from one side of a membrane to the other.
22892	substrate-specific transporter activity	F	Enables the directed movement of a specific substance or group of related substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells.
22893	low-affinity tryptophan transmembrane transporter activity	F	Catalysis of the low-affinity transfer of L-tryptophan from one side of a membrane to the other. Tryptophan is 2-amino-3-(1H-indol-3-yl)propanoic acid. In low-affinity transport the transporter is able to bind the solute only if it is present at very high concentrations.
22894	Intermediate conductance calcium-activated potassium channel activity	F	Enables the transmembrane transfer of potassium by a channel with a unit conductance of 20 to 85 picoSiemens that opens in response to stimulus by internal calcium ions. Intermediate conductance calcium-activated potassium channels are more sensitive to calcium than are large conductance calcium-activated potassium channels. Transport by a channel involves catalysis of facilitated diffusion of a solute (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel, without evidence for a carrier-mediated mechanism.
22897	proton-dependent peptide secondary active transmembrane transporter activity	F	Catalysis of the transfer of a peptide from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by proton movement.
22898	regulation of transmembrane transporter activity	P	Any process that modulates the frequency, rate or extent of transmembrane transporter activity.
22900	electron transport chain	P	A process in which a series of electron carriers operate together to transfer electrons from donors to any of several different terminal electron acceptors to generate a transmembrane electrochemical gradient.
22904	respiratory electron transport chain	P	A process in which a series of electron carriers operate together to transfer electrons from donors such as NADH and FADH2 to any of several different terminal electron acceptors to generate a transmembrane electrochemical gradient.
23002	nuclear migration to embryo sac poles	P	Migration of the nuclei of the two-nucleate embryo sac to opposite poles of the cell.
23003	nuclear migration to the embryo sac center	P	Migration of one of the four nuclei at each pole of the eight-nucleate embryo sac, to the center of the cell.
23014	signal transduction by protein phosphorylation	P	A process in which the transfer of one or more phosphate groups to a substrate transmits a signal to the phosphorylated substrate.
23015	signal transduction by cis-phosphorylation	P	A process in which the transfer of one or more phosphate groups by a kinase to a residue in the same kinase molecule transmits a signal. For example, ligand-binding can induce autophosphorylation of the activated receptor, creating binding sites for intracellular signaling molecules.
23016	signal transduction by trans-phosphorylation	P	A process in which the transfer of one or more phosphate groups by a kinase to a residue in a different protein molecule transmits a signal.
23019	signal transduction involved in regulation of gene expression	P	Any process that modulates the frequency, rate or extent of gene expression as a consequence of a process in which a signal is released and/or conveyed from one location to another.
23021	termination of signal transduction	P	The signaling process in which signal transduction is brought to an end rather than being reversibly modulated.
23022	termination of T cell signal transduction	P	The signaling process in which T cell signal transduction is brought to an end rather than being reversibly modulated.
23023	MHC protein complex binding	F	Interacting selectively and non-covalently with the major histocompatibility complex.
23024	MHC class I protein complex binding	F	Interacting selectively and non-covalently with the class I major histocompatibility complex.
23025	MHC class Ib protein complex binding	F	Interacting selectively and non-covalently with the class Ib major histocompatibility complex.
23026	MHC class II protein complex binding	F	Interacting selectively and non-covalently with the class II major histocompatibility complex.
23027	MHC class I protein binding, via antigen binding groove	F	Interacting selectively and non-covalently with major histocompatibility complex class I molecules via the antigen binding groove.
23028	MHC class I protein binding, via lateral surface	F	Interacting selectively and non-covalently with major histocompatibility complex class I molecules via the lateral surface.
23029	MHC class Ib protein binding	F	Interacting selectively and non-covalently with major histocompatibility complex class Ib molecules.
23030	MHC class Ib protein binding, via antigen binding groove	F	Interacting selectively and non-covalently with major histocompatibility complex class Ib molecules via the antigen binding groove.
23031	MHC class Ib protein binding, via lateral surface	F	Interacting selectively and non-covalently with major histocompatibility complex class Ib molecules via the lateral surface.
23035	CD40 signaling pathway	P	A series of molecular signals initiated by the binding of the cell surface receptor CD40 to one of its physiological ligands, and ending with regulation of a downstream cellular process, e.g. transcription.
23041	neuronal signal transduction	P	The process in which an activated neuronal cell receptor conveys information down a signaling pathway, resulting in a change in the function or state of a cell. This process may be intracellular or intercellular.
23045	signal transduction by conformational transition	P	A process where induction of a conformational change in a molecule transmits a signal to that molecule.
23051	regulation of signaling	P	Any process that modulates the frequency, rate or extent of a signaling process.
23052	signaling	P	The entirety of a process in which information is transmitted within a biological system. This process begins with an active signal and ends when a cellular response has been triggered.
23056	positive regulation of signaling	P	Any process that activates, maintains or increases the frequency, rate or extent of a signaling process.
23057	negative regulation of signaling	P	Any process that stops, prevents, or reduces the frequency, rate or extent of a signaling process.
23058	adaptation of signaling pathway	P	The regulation of a signal transduction pathway in response to a stimulus upon prolonged exposure to that stimulus.
23059	positive adaptation of signaling pathway	P	The positive regulation of a signal transduction pathway in response to a stimulus upon prolonged exposure to that stimulus.
23061	signal release	P	The process in which a signal is secreted or discharged into the extracellular medium from a cellular source.
30001	metal ion transport	P	The directed movement of metal ions, any metal ion with an electric charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
30002	cellular anion homeostasis	P	Any process involved in the maintenance of an internal steady state of anions at the level of a cell.
30003	cellular cation homeostasis	P	Any process involved in the maintenance of an internal steady state of cations at the level of a cell.
30004	cellular monovalent inorganic cation homeostasis	P	Any process involved in the maintenance of an internal steady state of monovalent inorganic cations at the level of a cell.
30007	cellular potassium ion homeostasis	P	Any process involved in the maintenance of an internal steady state of potassium ions at the level of a cell.
30008	TRAPP complex	C	A large complex that acts as a tethering factor involved in transporting vesicles from the ER through the Golgi to the plasma membrane. A TRAPP (transport protein particle) complex has a core set of proteins which are joined by specific subunits depending on the cellular component where a given TRAPP complex is active.
30010	establishment of cell polarity	P	The specification and formation of anisotropic intracellular organization or cell growth patterns.
30011	maintenance of cell polarity	P	The maintenance of established anisotropic intracellular organization or cell growth patterns.
30014	CCR4-NOT complex	C	The evolutionarily conserved CCR4-NOT complex is involved in several aspects of mRNA metabolism, including repression and activation of mRNA initiation, control of mRNA elongation, and the deadenylation and subsequent degradation of mRNA. In Saccharomyces the CCR4-NOT complex comprises a core complex of 9 proteins (Ccr4p, Caf1p, Caf40p, Caf130p, Not1p, Not2p, Not3p, Not4p, and Not5p), Caf4p, Caf16p, and several less well characterized proteins.
30015	CCR4-NOT core complex	C	The core of the CCR4-NOT complex. In Saccharomyces the CCR4-NOT core complex comprises Ccr4p, Caf1p, Caf40p, Caf130p, Not1p, Not2p, Not3p, Not4p, and Not5p.
30016	myofibril	C	The contractile element of skeletal and cardiac muscle; a long, highly organized bundle of actin, myosin, and other proteins that contracts by a sliding filament mechanism.
30017	sarcomere	C	The repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs.
30018	Z disc	C	Platelike region of a muscle sarcomere to which the plus ends of actin filaments are attached.
30020	extracellular matrix structural constituent conferring tensile strength	F	A constituent of the extracellular matrix that enables the matrix to resist longitudinal stress.
30021	extracellular matrix structural constituent conferring compression resistance	F	A constituent of the extracellular matrix that enables the matrix to resist compressive forces; often a proteoglycan.
30023	extracellular matrix constituent conferring elasticity	F	A component of the extracellular matrix that enables the matrix to recoil after transient stretching.
30026	cellular manganese ion homeostasis	P	Any process involved in the maintenance of an internal steady state of manganese ions at the level of a cell.
30027	lamellipodium	C	A thin sheetlike process extended by the leading edge of a migrating cell or extending cell process; contains a dense meshwork of actin filaments.
30029	actin filament-based process	P	Any cellular process that depends upon or alters the actin cytoskeleton, that part of the cytoskeleton comprising actin filaments and their associated proteins.
30030	cell projection organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a prolongation or process extending from a cell, e.g. a flagellum or axon.
30031	cell projection assembly	P	Formation of a prolongation or process extending from a cell, e.g. a flagellum or axon.
30032	lamellipodium assembly	P	Formation of a lamellipodium, a thin sheetlike extension of the surface of a migrating cell.
30033	microvillus assembly	P	Formation of a microvillus, a thin cylindrical membrane-covered projection on the surface of a cell.
30034	microvillar actin bundle assembly	P	Assembly of the parallel bundle of actin filaments at the core of a microvillus.
30035	microspike assembly	P	Formation of a microspike, a dynamic, actin-rich projection extending from the surface of a migrating animal cell.
30036	actin cytoskeleton organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins.
30037	actin filament reorganization involved in cell cycle	P	The cell cycle process in which rearrangement of the spatial distribution of actin filaments and associated proteins occurs.
30038	contractile actin filament bundle assembly	P	Assembly of actin filament bundles in which the filaments are loosely packed (approximately 30-60 nm apart) and arranged with opposing polarities; the loose packing allows myosin (usually myosin-II) to enter the bundle.
30041	actin filament polymerization	P	Assembly of actin filaments by the addition of actin monomers to a filament.
30042	actin filament depolymerization	P	Disassembly of actin filaments by the removal of actin monomers from a filament.
30043	actin filament fragmentation	P	The severing of actin filaments into numerous short fragments, usually mediated by actin severing proteins.
30046	parallel actin filament bundle assembly	P	Assembly of actin filament bundles in which the filaments are tightly packed (approximately 10-20 nm apart) and oriented with the same polarity.
30047	actin modification	P	Covalent modification of an actin molecule.
30048	actin filament-based movement	P	Movement of organelles or other particles along actin filaments, or sliding of actin filaments past each other, mediated by motor proteins.
30049	muscle filament sliding	P	The sliding of actin thin filaments and myosin thick filaments past each other in muscle contraction. This involves a process of interaction of myosin located on a thick filament with actin located on a thin filament. During this process ATP is split and forces are generated.
30050	vesicle transport along actin filament	P	Movement of a vesicle along an actin filament, mediated by motor proteins.
30054	cell junction	C	A cellular component that forms a specialized region of connection between two or more cells or between a cell and the extracellular matrix. At a cell junction, anchoring proteins extend through the plasma membrane to link cytoskeletal proteins in one cell to cytoskeletal proteins in neighboring cells or to proteins in the extracellular matrix.
30055	cell-substrate junction	C	A cell junction that forms a connection between a cell and the extracellular matrix.
30056	hemidesmosome	C	A cell-substrate junction (attachment structure) found in epithelial cells that links intermediate filaments to extracellular matrices via transmembrane complexes. In vertebrates, hemidesmosomes mediate contact between the basal side of epithelial cells and the basal lamina. In C. elegans, hemidesmosomes connect epithelial cells to distinct extracellular matrices on both the apical and basal cell surfaces.
30057	desmosome	C	A cell-cell junction in which: on the cytoplasmic surface of each interacting plasma membrane is a dense plaque composed of a mixture of intracellular anchor proteins; a bundle of keratin intermediate filaments is attached to the surface of each plaque; transmembrane adhesion proteins of the cadherin family bind to the plaques and interact through their extracellular domains to hold the adjacent membranes together by a Ca2+-dependent mechanism.
30058	amine dehydrogenase activity	F	Catalysis of the reaction: R-CH2-NH2 + H2O + acceptor = R-CHO + NH3 + reduced acceptor.
30059	aralkylamine dehydrogenase (azurin) activity	F	Catalysis of the reaction: H(2)O + arCH(2)NH(2) + 2 azurin = 2 reduced azurin + ArCHO + NH(3). The symbol arCH(2)NH(2) represents an aralkylamine and ArCHO is an aryl aldehyde.
30060	L-malate dehydrogenase activity	F	Catalysis of the reaction: (S)-malate + NAD+ = oxaloacetate + NADH + H+.
30061	mitochondrial crista	C	Any of the inward folds of the mitochondrial inner membrane. Their number, extent, and shape differ in mitochondria from different tissues and organisms. They appear to be devices for increasing the surface area of the mitochondrial inner membrane, where the enzymes of electron transport and oxidative phosphorylation are found. Their shape can vary with the respiratory state of the mitochondria.
30062	mitochondrial tricarboxylic acid cycle enzyme complex	C	Any of the heteromeric enzymes, located in the mitochondrion, that act in the tricarboxylic acid (TCA) cycle.
30070	insulin processing	P	The formation of mature insulin by proteolysis of the precursor preproinsulin. The signal sequence is first cleaved from preproinsulin to form proinsulin; proinsulin is then cleaved to release the C peptide, leaving the A and B chains of mature insulin linked by disulfide bridges.
30071	regulation of mitotic metaphase/anaphase transition	P	Any process that modulates the frequency, rate or extent of the cell cycle process in which a cell progresses from metaphase to anaphase during mitosis, triggered by the activation of the anaphase promoting complex by Cdc20/Sleepy homolog which results in the degradation of Securin.
30072	peptide hormone secretion	P	The regulated release of a peptide hormone from a cell.
30073	insulin secretion	P	The regulated release of proinsulin from secretory granules (B granules) in the B cells of the pancreas; accompanied by cleavage of proinsulin to form mature insulin.
30075	bacterial thylakoid	C	A thylakoid that is derived from and attached to, but not necessarily continuous with, the plasma membrane, and is not enclosed in a plastid. It bears the photosynthetic pigments in photosynthetic cyanobacteria.
30076	light-harvesting complex	C	A protein-pigment complex that may be closely or peripherally associated to photosynthetic reaction centers that participate in harvesting and transferring radiant energy to the reaction center.
30077	plasma membrane light-harvesting complex	C	A plasma membrane protein-pigment complex that may be closely or peripherally associated to photosynthetic reaction centers that participate in harvesting and transferring radiant energy to the reaction center. Examples of this complex are found in bacterial species.
30078	light-harvesting complex, core complex	C	Light harvesting complex associated with the reaction complex of photosynthetic purple bacteria.
30079	light-harvesting complex, peripheral complex	C	Bacteriochlorophyll a binding complex that is peripherally associated to the bacterial reaction center.
30080	B875 antenna complex	C	Protein complex that surrounds and transfers excitation energy directly to the bacterial reaction center; binds bacteriochlorophyll a and has a single absorption band between 870 and 890 nm.
30081	B800-820 antenna complex	C	Protein-pigment complex that absorbs light at 800 and 820 nm; is peripherally associated to the bacterial reaction center; transfers excitation energy to the B875 antenna complex.
30082	B800-850 antenna complex	C	Protein-pigment complex that absorbs light at 800 and 850 nm; is peripherally associated to the bacterial reaction center; transfers excitation energy to the B875 antenna complex.
30083	PSI associated light-harvesting complex I, LHCIa subcomplex	C	A pigment protein complex that forms part of the photosystem I associated light-harvesting complex I; contains two proteins (usually about 24 and 21.5 kDa); has a fluorescence maximum between 680 and 690 nm.
30084	PSI associated light-harvesting complex I, LHCIb subcomplex	C	A pigment protein complex that forms part of the photosystem I associated light-harvesting complex I; contains two proteins (usually about 20 kDa); has a fluorescence maximum of 730 nm.
30085	PSII associated light-harvesting complex II, peripheral complex, LHCIIb subcomplex	C	A pigment protein complex that forms part of the photosystem II associated light-harvesting complex II; contains two proteins (usually about 28 and 27 kDa), and may contain a third; peripherally located relative to other LHC polypeptides.
30089	phycobilisome	C	Any of the granules, approximately 32 nm x 48 nm and consisting of highly aggregated phycobiliproteins, that are attached in arrays to the external face of a thylakoid membrane in algae of the phyla Cyanophyta and Rhodophyta, where they function as light-harvesting devices in photosynthesis. Excitation energy in the phycobilisome flows in the sequence: phycoerythrin, phycocyanin, allophycocyanin before passing to the antenna chlorophyll of photosystem II.
30091	protein repair	P	The process of restoring a protein to its original state after damage by such things as oxidation or spontaneous decomposition of residues.
30093	chloroplast photosystem I	C	Photosystem located in the chloroplast that functions as a light-dependent plastocyanin-ferredoxin oxidoreductase, transferring electrons from plastocyanin to ferredoxin. An example of this is found in Arabidopsis thaliana.
30094	plasma membrane-derived photosystem I	C	A protein complex located in the plasma membrane-derived thylakoid. The photosystem functions as a light-dependent plastocyanin-ferredoxin oxidoreductase, transferring electrons from plastocyanin to ferredoxin. Examples of this complex are found in bacterial species.
30095	chloroplast photosystem II	C	An integral chloroplast membrane complex containing the P680 reaction center. In the light, PSII functions as a water-plastoquinone oxidoreductase, transferring electrons from water to plastoquinone.
30096	plasma membrane-derived thylakoid photosystem II	C	A protein complex, located in the membrane-derived thylakoid, containing the P680 reaction center. In the light, PSII functions as a water-plastoquinone oxidoreductase, transferring electrons from water to plastoquinone.
30097	hemopoiesis	P	The process whose specific outcome is the progression of the myeloid and lymphoid derived organ/tissue systems of the blood and other parts of the body over time, from formation to the mature structure. The site of hemopoiesis is variable during development, but occurs primarily in bone marrow or kidney in many adult vertebrates.
30098	lymphocyte differentiation	P	The process in which a relatively unspecialized precursor cell acquires specialized features of a lymphocyte. A lymphocyte is a leukocyte commonly found in the blood and lymph that has the characteristics of a large nucleus, a neutral staining cytoplasm, and prominent heterochromatin.
30099	myeloid cell differentiation	P	The process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of any cell of the myeloid leukocyte, megakaryocyte, thrombocyte, or erythrocyte lineages.
30100	regulation of endocytosis	P	Any process that modulates the frequency, rate or extent of endocytosis.
30101	natural killer cell activation	P	The change in morphology and behavior of a natural killer cell in response to a cytokine, chemokine, cellular ligand, or soluble factor.
30103	vasopressin secretion	P	The regulated release of vasopressin from secretory granules into the blood.
30104	water homeostasis	P	Any process involved in the maintenance of an internal steady state of water within an organism or cell.
30107	HLA-A specific inhibitory MHC class I receptor activity	F	Combining with a MHC class I molecule of the HLA-A subclass to mediate signaling that inhibits activation of a lymphocyte.
30108	HLA-A specific activating MHC class I receptor activity	F	Combining with a MHC class I molecule of the HLA-A subclass to mediate signaling that activates a lymphocyte.
30109	HLA-B specific inhibitory MHC class I receptor activity	F	Combining with a MHC class I molecule of the HLA-B subclass to mediate signaling that inhibits activation of a lymphocyte.
30110	HLA-C specific inhibitory MHC class I receptor activity	F	Combining with a MHC class I molecule of the HLA-C subclass to mediate signaling that inhibits activation of a lymphocyte.
30111	regulation of Wnt signaling pathway	P	Any process that modulates the frequency, rate or extent of the activity of the Wnt signal transduction pathway.
30112	glycocalyx	C	A viscous, carbohydrate rich layer at the outermost periphery of a cell.
30114	slime layer	C	A slime layer is an easily removed, diffuse, unorganized layer of extracellular material that surrounds a cell. Specifically this consists mostly of exopolysaccharides, glycoproteins, and glycolipids.
30115	S-layer	C	A crystalline protein layer surrounding some bacteria.
30116	glial cell-derived neurotrophic factor receptor binding	F	A growth factor that binds selectively and non-covalently to glial cell-derived neurotrophic factor receptors.
30117	membrane coat	C	Any of several different proteinaceous coats that can associate with membranes. Membrane coats include those formed by clathrin plus an adaptor complex, the COPI and COPII complexes, and possibly others. They are found associated with membranes on many vesicles as well as other membrane features such as pits and perhaps tubules.
30118	clathrin coat	C	A membrane coat found on coated pits and some coated vesicles; consists of polymerized clathrin triskelions, each comprising three clathrin heavy chains and three clathrin light chains, linked to the membrane via one of the AP adaptor complexes.
30119	AP-type membrane coat adaptor complex	C	Any of several heterotetrameric complexes that link clathrin (or another coat-forming molecule, as hypothesized for AP-3 and AP-4) to a membrane surface; they are found on coated pits and coated vesicles, and mediate sorting of cargo proteins into vesicles. Each AP complex contains two large (a beta and one of either an alpha, gamma, delta, or epsilon) subunits (110-130 kDa), a medium (mu) subunit (approximately 50 kDa), and a small (sigma) subunit (15-20 kDa).
30120	vesicle coat	C	A membrane coat found on a coated vesicle.
30121	AP-1 adaptor complex	C	A heterotetrameric AP-type membrane coat adaptor complex that consists of beta1, gamma, mu1 and sigma1 subunits and links clathrin to the membrane surface of a vesicle; vesicles with AP-1-containing coats are normally found primarily in the trans-Golgi network. In at least humans, the AP-1 complex can be heterogeneric due to the existence of multiple subunit isoforms encoded by different genes (gamma1 and gamma2, mu1A and mu1B, and sigma1A, sigma1B and sigma1C).
30122	AP-2 adaptor complex	C	A heterotetrameric AP-type membrane coat adaptor complex that consists of alpha, beta2, mu2 and sigma2 subunits, and links clathrin to the membrane surface of a vesicle, and the cargo receptors during receptor/clathrin mediated endocytosis. Vesicles with AP-2-containing coats are normally found primarily near the plasma membrane, on endocytic vesicles. In at least humans, the AP-2 complex can be heterogeneric due to the existence of multiple subunit isoforms encoded by different alpha genes (alphaA and alphaC).
30123	AP-3 adaptor complex	C	A heterotetrameric AP-type membrane coat adaptor complex that consists of beta3, delta, mu3 and sigma3 subunits and is found associated with endosomal membranes. AP-3 does not appear to associate with clathrin in all organisms. In at least humans, the AP-3 complex can be heterogeneric due to the existence of multiple subunit isoforms encoded by different genes (beta3A and beta3B, mu3A and mu3B, and sigma3A and sigma3B).
30124	AP-4 adaptor complex	C	An AP-type membrane coat adaptor complex that consists of beta4, epsilon, mu4 and sigma4 subunits and is found associated with membranes in the trans-Golgi network; it is not clear whether AP-4 forms clathrin coats in vivo.
30125	clathrin vesicle coat	C	A clathrin coat found on a vesicle.
30126	COPI vesicle coat	C	One of two multimeric complexes that forms a membrane vesicle coat. The mammalian COPI subunits are called alpha-, beta-, beta'-, gamma-, delta-, epsilon- and zeta-COP. Vesicles with COPI coats are found associated with Golgi membranes at steady state.
30127	COPII vesicle coat	C	One of two multimeric complexes that forms a membrane vesicle coat. COPII is best characterized in S. cerevisiae, where the subunits are called Sar1p, Sec13p, Sec31p, Sec23p, and Sec24p. Vesicles with COPII coats are found associated with endoplasmic reticulum (ER) membranes at steady state.
30128	clathrin coat of endocytic vesicle	C	A clathrin coat found on an endocytic vesicle.
30129	clathrin coat of synaptic vesicle	C	A clathrin coat found on a synaptic vesicle.
30130	clathrin coat of trans-Golgi network vesicle	C	A clathrin coat found on a vesicle of the trans-Golgi network.
30131	clathrin adaptor complex	C	A membrane coat adaptor complex that links clathrin to a membrane.
30132	clathrin coat of coated pit	C	The coat found on coated pits and the coated vesicles derived from coated pits; comprises clathrin and the AP-2 adaptor complex.
30133	transport vesicle	C	Any of the vesicles of the constitutive secretory pathway, which carry cargo from the endoplasmic reticulum to the Golgi, between Golgi cisternae, from the Golgi to the ER (retrograde transport) or to destinations within or outside the cell.
30134	ER to Golgi transport vesicle	C	A vesicle that mediates transport from the endoplasmic reticulum to the Golgi complex; bears a coat formed of the COPII coat complex proteins; such vesicles found associated with endoplasmic reticulum (ER) membranes at steady state, and are involved in ER to Golgi (anterograde) vesicle transport.
30135	coated vesicle	C	Small membrane-bounded organelle formed by pinching off of a coated region of membrane. Some coats are made of clathrin, whereas others are made from other proteins.
30136	clathrin-coated vesicle	C	A vesicle with a coat formed of clathrin connected to the membrane via one of the clathrin adaptor complexes.
30137	COPI-coated vesicle	C	A vesicle with a coat formed of the COPI coat complex proteins. COPI-coated vesicles are found associated with Golgi membranes at steady state, are involved in Golgi to endoplasmic reticulum (retrograde) vesicle transport, and possibly also in intra-Golgi transport.
30139	endocytic vesicle	C	A membrane-bounded intracellular vesicle formed by invagination of the plasma membrane around an extracellular substance. Endocytic vesicles fuse with early endosomes to deliver the cargo for further sorting.
30140	trans-Golgi network transport vesicle	C	A vesicle that mediates transport between the trans-Golgi network and other parts of the cell.
30141	secretory granule	C	A small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion. Secretory granules move towards the periphery of the cell and upon stimulation, their membranes fuse with the cell membrane, and their protein load is exteriorized. Processing of the contained protein may take place in secretory granules.
30142	Golgi to ER transport vesicle	C	A vesicle that mediates transport from the Golgi to the endoplasmic reticulum.
30143	inter-Golgi transport vesicle	C	A vesicle that mediates transport of cargo within the Golgi complex (for example, between cisternae of the Golgi stack).
30144	alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity	F	Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + N-acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl-1,3(6)-(N-acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl,1,6(3))-beta-D-mannosyl-1,4-N-acetyl-beta-D-glucosaminyl-R = UDP + N-acetyl-beta-D-glucosaminyl-1,2-(N-acetyl-beta-D-glucosaminyl-1,6)-1,2-alpha-D-mannosyl-1,3(6)-(N-acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl-1,6(3))-beta-D-mannosyl-1,4-N-acetyl-beta-D-glucosaminyl-R. Only branched mannose glycopeptides with non-reducing N-acetylglucosamine terminal residues act as acceptors.
30145	manganese ion binding	F	Interacting selectively and non-covalently with manganese (Mn) ions.
30148	sphingolipid biosynthetic process	P	The chemical reactions and pathways resulting in the formation of sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid).
30149	sphingolipid catabolic process	P	The chemical reactions and pathways resulting in the breakdown of sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid).
30150	protein import into mitochondrial matrix	P	The import of proteins across the outer and inner mitochondrial membranes into the matrix. Unfolded proteins enter the mitochondrial matrix with a chaperone protein; the information required to target the precursor protein from the cytosol to the mitochondrial matrix is contained within its N-terminal matrix-targeting sequence. Translocation of precursors to the matrix occurs at the rare sites where the outer and inner membranes are close together.
30151	molybdenum ion binding	F	Interacting selectively and non-covalently with molybdenum (Mo) ions.
30152	bacteriocin biosynthetic process	P	The chemical reactions and pathways resulting in the formation of a bacteriocin, any of a heterogeneous group of polypeptide antibiotics that are secreted by certain bacterial strains and are able to kill cells of other susceptible (frequently related) strains after adsorption at specific receptors on the cell surface. They include the colicins, and their mechanisms of action vary.
30153	bacteriocin immunity	P	A process that mediates resistance to a bacteriocin: any of a heterogeneous group of polypeptide antibiotics that are secreted by certain bacterial strains and are able to kill cells of other susceptible (frequently related) strains after adsorption at specific receptors on the cell surface. They include the colicins, and their mechanisms of action vary.
30154	cell differentiation	P	The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state.
30155	regulation of cell adhesion	P	Any process that modulates the frequency, rate or extent of attachment of a cell to another cell or to the extracellular matrix.
30156	benzodiazepine receptor binding	F	Interacting selectively and non-covalently with the peripheral benzodiazepine receptor (PBR).
30157	pancreatic juice secretion	P	The regulated release of pancreatic juice by the exocrine pancreas into the upper part of the intestine. Pancreatic juice is slightly alkaline and contains numerous enzymes and inactive enzyme precursors including alpha-amylase, chymotrypsinogen, lipase, procarboxypeptidase, proelastase, prophospholipase A2, ribonuclease, and trypsinogen. Its high concentration of bicarbonate ions helps to neutralize the acid from the stomach.
30158	protein xylosyltransferase activity	F	Catalysis of the transfer of a beta-D-xylosyl residue from UDP-D-xylose to the serine hydroxyl group of an acceptor protein substrate.
30159	receptor signaling complex scaffold activity	F	Functions to provide a physical support for the assembly of a multiprotein receptor signaling complex.
30160	GKAP/Homer scaffold activity	F	Functions as a physical support bridging the N-methyl-D-aspartate receptor-PSD-95-GKAP complex and the mGluR-Homer complex, which are involved in receptor signaling in synapses.
30162	regulation of proteolysis	P	Any process that modulates the frequency, rate or extent of the hydrolysis of a peptide bond or bonds within a protein.
30163	protein catabolic process	P	The chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds.
30164	protein denaturation	P	Structural change in proteins which destroys the native, active configuration without rupture of peptide bonds.
30165	PDZ domain binding	F	Interacting selectively and non-covalently with a PDZ domain of a protein, a domain found in diverse signaling proteins.
30166	proteoglycan biosynthetic process	P	The chemical reactions and pathways resulting in the formation of proteoglycans, any glycoprotein in which the carbohydrate units are glycosaminoglycans.
30167	proteoglycan catabolic process	P	The chemical reactions and pathways resulting in the breakdown of proteoglycans, any glycoprotein in which the carbohydrate units are glycosaminoglycans.
30168	platelet activation	P	A series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue. These events include shape change, adhesiveness, aggregation, and release reactions. When carried through to completion, these events lead to the formation of a stable hemostatic plug.
30169	low-density lipoprotein particle binding	F	Interacting selectively and non-covalently with a low-density lipoprotein particle, a lipoprotein particle that is rich in cholesterol esters and low in triglycerides, is typically composed of APOB100 and APOE, and has a density of 1.02-1.06 g/ml and a diameter of between 20-25 nm.
30170	pyridoxal phosphate binding	F	Interacting selectively and non-covalently with pyridoxal 5' phosphate, 3-hydroxy-5-(hydroxymethyl)-2-methyl4-pyridine carboxaldehyde 5' phosphate, the biologically active form of vitamin B6.
30171	voltage-gated proton channel activity	F	Enables the transmembrane transfer of a proton by a voltage-gated channel. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.
30172	troponin C binding	F	Interacting selectively and non-covalently with troponin C, the calcium-binding subunit of the troponin complex.
30173	integral component of Golgi membrane	C	The component of the Golgi membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
30174	regulation of DNA-dependent DNA replication initiation	P	Any process that modulates the frequency, rate or extent of initiation of DNA-dependent DNA replication; the process in which DNA becomes competent to replicate. In eukaryotes, replication competence is established in early G1 and lost during the ensuing S phase.
30175	filopodium	C	Thin, stiff, actin-based protrusion extended by the leading edge of a motile cell such as a crawling fibroblast or amoeba, or an axonal or dendritic growth cone, or a dendritic shaft.
30176	integral component of endoplasmic reticulum membrane	C	The component of the endoplasmic reticulum membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
30177	positive regulation of Wnt signaling pathway	P	Any process that activates or increases the frequency, rate or extent of Wnt signal transduction.
30178	negative regulation of Wnt signaling pathway	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the Wnt signaling pathway.
30182	neuron differentiation	P	The process in which a relatively unspecialized cell acquires specialized features of a neuron.
30183	B cell differentiation	P	The process in which a precursor cell type acquires the specialized features of a B cell. A B cell is a lymphocyte of B lineage with the phenotype CD19-positive and capable of B cell mediated immunity.
30184	nitric oxide transmembrane transporter activity	F	Enables the directed movement of nitric oxide, nitrogen monoxide, from one side of a membrane to the other.
30185	nitric oxide transport	P	The directed movement of nitric oxide, nitrogen monoxide, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
30186	melatonin metabolic process	P	The chemical reactions and pathways involving melatonin (N-acetyl-5-methoxytryptamine).
30187	melatonin biosynthetic process	P	The chemical reactions and pathways resulting in the formation of melatonin (N-acetyl-5-methoxytryptamine).
30193	regulation of blood coagulation	P	Any process that modulates the frequency, rate or extent of blood coagulation.
30194	positive regulation of blood coagulation	P	Any process that activates or increases the frequency, rate or extent of blood coagulation.
30195	negative regulation of blood coagulation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of blood coagulation.
30196	cyanide hydratase activity	F	Catalysis of the reaction: formamide = H(2)O + hydrogen cyanide.
30197	extracellular matrix constituent, lubricant activity	F	Functions as a lubricant for an extracellular matrix, such as a mucous membrane.
30198	extracellular matrix organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an extracellular matrix.
30199	collagen fibril organization	P	Any process that determines the size and arrangement of collagen fibrils within an extracellular matrix.
30200	heparan sulfate proteoglycan catabolic process	P	The chemical reactions and pathways resulting in the breakdown of proteoglycan containing heparan sulfate, any member of a group of glycosaminoglycans that have repeat units consisting of alternating alpha-(1->4) linked hexuronic acid and glucosamine residues, the former being a mixture of sulfated and nonsulfated D-glucuronic and L-iduronic acids, and the latter being either sulfated or acetylated on its amino group as well as sulfated on one of its hydroxyl groups.
30201	heparan sulfate proteoglycan metabolic process	P	The chemical reactions and pathways involving any proteoglycan containing heparan sulfate, any member of a group of glycosaminoglycans that have repeat units consisting of alternating alpha-(1->4)-linked hexuronic acid and glucosamine residues, the former being a mixture of sulfated and nonsulfated D-glucuronic and L-iduronic acids, and the latter being either sulfated or acetylated on its amino group as well as sulfated on one of its hydroxyl groups.
30202	heparin metabolic process	P	The chemical reactions and pathways involving heparin, any member of a group of glycosaminoglycans found mainly as an intracellular component of mast cells. They are similar to heparan sulfates but are of somewhat higher average Mr (6000-20000) and contain fewer N-acetyl groups and more N-sulfate and O-sulfate groups; they may be attached in the same manner to protein, forming proteoglycans. They consist predominantly of alternating alpha-(1->4)-linked D-galactose and N-acetyl-D-glucosamine-6-sulfate residues.
30203	glycosaminoglycan metabolic process	P	The chemical reactions and pathways involving glycosaminoglycans, any one of a group of polysaccharides that contain amino sugars. Formerly known as mucopolysaccharides, they include hyaluronic acid and chondroitin, which provide lubrication in joints and form part of the matrix of cartilage. The three-dimensional structure of these molecules enables them to trap water, which forms a gel and gives glycosaminoglycans their elastic properties.
30204	chondroitin sulfate metabolic process	P	The chemical reactions and pathways involving chondroitin sulfate, any member of a group of 10-60 kDa glycosaminoglycans, widely distributed in cartilage and other mammalian connective tissues, the repeat units of which consist of beta-(1,4)-linked D-glucuronyl beta-(1,3)-N-acetyl-D-galactosamine sulfate. They usually occur linked to a protein to form proteoglycans. Two subgroups exist, one in which the sulfate is on the 4-position (chondroitin sulfate A) and the second in which it is in the 6-position (chondroitin sulfate C). They often are polydisperse and often differ in the degree of sulfation from tissue to tissue. The chains of repeating disaccharide are covalently linked to the side chains of serine residues in the polypeptide backbone of a protein by a glycosidic attachment through the trisaccharide unit galactosyl-galactosyl-xylosyl. Chondroitin sulfate B is more usually known as dermatan sulfate.
30205	dermatan sulfate metabolic process	P	The chemical reactions and pathways involving dermatan sulfate, any of a group of glycosaminoglycans with repeats consisting of beta-(1,4)-linked L-iduronyl-beta-(1,3)-N-acetyl-D-galactosamine 4-sulfate units. They are important components of ground substance or intercellular cement of skin and some connective tissues.
30206	chondroitin sulfate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of chondroitin sulfate, any member of a group of 10-60 kDa glycosaminoglycans, widely distributed in cartilage and other mammalian connective tissues, the repeat units of which consist of beta-(1,4)-linked D-glucuronyl beta-(1,3)-N-acetyl-D-galactosamine sulfate.
30207	chondroitin sulfate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of chondroitin sulfate, any member of a group of 10-60 kDa glycosaminoglycans, widely distributed in cartilage and other mammalian connective tissues, the repeat units of which consist of beta-(1,4)-linked D-glucuronyl beta-(1,3)-N-acetyl-D-galactosamine sulfate.
30208	dermatan sulfate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of dermatan sulfate, any glycosaminoglycan with repeats consisting of beta-(1,4)-linked L-iduronyl-beta-(1,3)-N-acetyl-D-galactosamine 4-sulfate units.
30209	dermatan sulfate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of dermatan sulfate, any of a group of glycosaminoglycans with repeats consisting of beta-(1,4)-linked L-iduronyl-beta-(1,3)-N-acetyl-D-galactosamine 4-sulfate units.
30210	heparin biosynthetic process	P	The chemical reactions and pathways resulting in the formation of heparin, any member of a group of glycosaminoglycans of average Mr (6000-20000), consisting predominantly of alternating alpha-(1->4)-linked D-galactose and N-acetyl-D-glucosamine-6-sulfate residues.
30211	heparin catabolic process	P	The chemical reactions and pathways resulting in the breakdown of heparin, any member of a group of glycosaminoglycans of average Mr (6000-20000), consisting predominantly of alternating alpha-(1->4)-linked D-galactose and N-acetyl-D-glucosamine-6-sulfate residues.
30212	hyaluronan metabolic process	P	The chemical reactions and pathways involving hyaluronan, the naturally occurring anionic form of hyaluronic acid, any member of a group of glycosaminoglycans, the repeat units of which consist of beta-1,4 linked D-glucuronyl-beta-(1,3)-N-acetyl-D-glucosamine.
30213	hyaluronan biosynthetic process	P	The chemical reactions and pathways resulting in the formation of hyaluronan, the naturally occurring anionic form of hyaluronic acid, any member of a group of glycosaminoglycans, the repeat units of which consist of beta-1,4 linked D-glucuronyl-beta-(1,3)-N-acetyl-D-glucosamine.
30214	hyaluronan catabolic process	P	The chemical reactions and pathways resulting in the breakdown of hyaluronan, the naturally occurring anionic form of hyaluronic acid, any member of a group of glycosaminoglycans, the repeat units of which consist of beta-1,4 linked D-glucuronyl-beta-(1,3)-N-acetyl-D-glucosamine.
30215	semaphorin receptor binding	F	Interacting selectively and non-covalently with semaphorin receptors.
30216	keratinocyte differentiation	P	The process in which a relatively unspecialized cell acquires specialized features of a keratinocyte.
30217	T cell differentiation	P	The process in which a precursor cell type acquires characteristics of a more mature T-cell. A T cell is a type of lymphocyte whose definin characteristic is the expression of a T cell receptor complex.
30218	erythrocyte differentiation	P	The process in which a myeloid precursor cell acquires specializes features of an erythrocyte.
30219	megakaryocyte differentiation	P	The process in which a myeloid precursor cell acquires specializes features of a megakaryocyte.
30220	platelet formation	P	The process in which platelets bud from long processes extended by megakaryocytes.
30221	basophil differentiation	P	The process in which a relatively unspecialized myeloid precursor cell acquires specialized features of a basophil cell.
30222	eosinophil differentiation	P	The process in which a relatively unspecialized myeloid precursor cell acquires the specializes features of an eosinophil.
30223	neutrophil differentiation	P	The process in which a myeloid precursor cell acquires the specialized features of a neutrophil.
30224	monocyte differentiation	P	The process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of a monocyte.
30225	macrophage differentiation	P	The process in which a relatively unspecialized monocyte acquires the specialized features of a macrophage.
30226	apolipoprotein receptor activity	F	Combining with an apolipoprotein to initiate a change in cell activity.
30228	lipoprotein particle receptor activity	F	Combining with a lipoprotein particle and delivering the lipoprotein particle into the cell via endocytosis. A lipoprotein particle, also known as a lipoprotein, is a clathrate complex consisting of a lipid enwrapped in a protein host without covalent binding in such a way that the complex has a hydrophilic outer surface consisting of all the protein and the polar ends of any phospholipids.
30229	very-low-density lipoprotein particle receptor activity	F	Combining with a very-low-density lipoprotein particle and delivering the very-low-density lipoprotein into the cell via endocytosis.
30232	insulin control element activator complex	C	Transcription factor complex that binds to the insulin control element (ICE), a DNA sequence element found within the 5'-flanking region of the insulin gene, and activates ICE-mediated transcription.
30233	deoxynucleotide transmembrane transporter activity	F	Catalyzes transport of all four deoxy (d) NDPs, and, less efficiently, the corresponding dNTPs, in exchange for dNDPs, ADP, or ATP.
30234	enzyme regulator activity	F	Binds to and modulates the activity of an enzyme.
30235	nitric-oxide synthase regulator activity	F	Modulates the activity of nitric oxide synthase.
30237	female sex determination	P	The specification of female sex of an individual organism.
30238	male sex determination	P	The specification of male sex of an individual organism.
30239	myofibril assembly	P	Formation of myofibrils, the repeating units of striated muscle.
30240	skeletal muscle thin filament assembly	P	The aggregation, arrangement and bonding together of proteins to form the actin-based thin filaments of myofibrils in skeletal muscle.
30241	skeletal muscle myosin thick filament assembly	P	The aggregation, arrangement and bonding together of proteins to form the myosin-based thick filaments of myofibrils in skeletal muscle.
30242	pexophagy	P	The process in which peroxisomes are delivered to the vacuole and degraded in response to changing nutrient conditions.
30243	cellulose metabolic process	P	The chemical reactions and pathways involving cellulose, a linear beta1-4 glucan of molecular mass 50-400 kDa with the pyranose units in the -4C1 conformation.
30244	cellulose biosynthetic process	P	The chemical reactions and pathways resulting in the formation of cellulose, a linear beta1-4 glucan of molecular mass 50-400 kDa with the pyranose units in the -4C1 conformation.
30245	cellulose catabolic process	P	The chemical reactions and pathways resulting in the breakdown of cellulose, a linear beta1-4 glucan of molecular mass 50-400 kDa with the pyranose units in the -4C1 conformation.
30246	carbohydrate binding	F	Interacting selectively and non-covalently with any carbohydrate, which includes monosaccharides, oligosaccharides and polysaccharides as well as substances derived from monosaccharides by reduction of the carbonyl group (alditols), by oxidation of one or more hydroxy groups to afford the corresponding aldehydes, ketones, or carboxylic acids, or by replacement of one or more hydroxy group(s) by a hydrogen atom. Cyclitols are generally not regarded as carbohydrates.
30247	polysaccharide binding	F	Interacting selectively and non-covalently with any polysaccharide, a polymer of many (typically more than 10) monosaccharide residues linked glycosidically.
30248	cellulose binding	F	Interacting selectively and non-covalently with cellulose.
30249	guanylate cyclase regulator activity	F	Modulates the activity of guanylate cyclase.
30250	guanylate cyclase activator activity	F	Binds to and increases the activity of guanylate cyclase.
30251	guanylate cyclase inhibitor activity	F	Stops, prevents or reduces the activity of guanylate cyclase.
30252	growth hormone secretion	P	The regulated release of growth hormone from secretory granules into the blood.
30253	protein secretion by the type I secretion system	P	The process in which proteins are secreted into the extracellular milieu via the type I secretion system; secretion occurs in a continuous process without the distinct presence of periplasmic intermediates and does not involve proteolytic processing of secreted proteins.
30254	protein secretion by the type III secretion system	P	The process in which proteins are transferred into the extracellular milieu or directly into host cells by the bacterial type III secretion system; secretion occurs in a continuous process without the distinct presence of periplasmic intermediates and does not involve proteolytic processing of secreted proteins.
30255	protein secretion by the type IV secretion system	P	The process in which proteins are transferred into the extracellular milieu or directly into host cells, via the type IV protein secretion system.
30256	type I protein secretion system complex	C	A complex of three secretory proteins that carry out secretion in the type I secretion system: an inner membrane transport ATPase (termed ABC protein for ATP-binding cassette), which provides the energy for protein secretion; an outer membrane protein, which is exported via the sec pathway; and a membrane fusion protein, which is anchored in the inner membrane and spans the periplasmic space.
30257	type III protein secretion system complex	C	A complex of approximately 20 proteins, most of which are located in the cytoplasmic membrane that carries out protein secretion in the bacterial type III secretion system; type III secretion also requires a cytoplasmic, probably membrane-associated ATPase.
30258	lipid modification	P	The covalent alteration of one or more fatty acids in a lipid, resulting in a change in the properties of the lipid.
30259	lipid glycosylation	P	Covalent attachment of a glycosyl residue to a lipid molecule.
30260	entry into host cell	P	The invasion by an organism of a cell of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
30261	chromosome condensation	P	The progressive compaction of dispersed interphase chromatin into threadlike chromosomes prior to mitotic or meiotic nuclear division, or during apoptosis, in eukaryotic cells.
30262	apoptotic nuclear changes	P	Alterations undergone by nuclei at the molecular and morphological level as part of the execution phase of apoptosis.
30263	apoptotic chromosome condensation	P	The compaction of chromatin during apoptosis.
30264	nuclear fragmentation involved in apoptotic nuclear change	P	The breakdown of the nucleus into small membrane-bounded compartments, or blebs, each of which contain compacted DNA.
30265	phospholipase C-activating rhodopsin mediated signaling pathway	P	The series of molecular signals generated as a consequence of a rhodopsin molecule being activated by a photon, where the pathway proceeds with activation of phospholipase C (PLC) and a subsequent release of inositol trisphosphate (IP3) and diacylglycerol (DAG).
30266	quinate 3-dehydrogenase (NAD+) activity	F	Catalysis of the reaction: (-)-quinate + NAD+ = (-)-3-dehydroquinate + NADH + H+.
30267	glyoxylate reductase (NADP) activity	F	Catalysis of the reaction: glycolate + NADP+ = glyoxylate + NADPH + H+.
30268	methylenetetrahydromethanopterin dehydrogenase activity	F	Catalysis of the reaction: 5,10-methylenetetrahydromethanopterin + coenzyme F420 + 2 H(+) = 5,10-methenyl-5,6,7,8-tetrahydromethanopterin + reduced coenzyme F420.
30269	tetrahydromethanopterin S-methyltransferase activity	F	Catalysis of the reaction: 5-methyltetrahydromethanopterin + coenzyme M = 5,6,7,8-tetrahydromethanopterin + methyl-coenzyme M. 2-(methylthio)ethanesulfonate is also known as methyl-CoM.
30270	formylmethanofuran-tetrahydromethanopterin N-formyltransferase activity	F	Catalysis of the reaction: 5,6,7,8-tetrahydromethanopterin + N-formylmethanofuran + H(+) = N(5)-formyl-5,6,7,8-tetrahydromethanopterin + methanofuran.
30272	5-formyltetrahydrofolate cyclo-ligase activity	F	Catalysis of the reaction: 5-formyltetrahydrofolate + ATP = 5,10-methenyltetrahydrofolate + ADP + H(+) + phosphate.
30273	melanin-concentrating hormone receptor activity	F	Combining with the cyclic peptide hormone melanin-concentrating hormone to initiate a change in cell activity.
30274	LIM domain binding	F	Interacting selectively and non-covalently with a LIM domain (for Lin-11 Isl-1 Mec-3) of a protein, a domain with seven conserved cysteine residues and a histidine, that binds two zinc ions and acts as an interface for protein-protein interactions.
30275	LRR domain binding	F	Interacting selectively and non-covalently with a LRR domain (leucine rich repeats) of a protein.
30276	clathrin binding	F	Interacting selectively and non-covalently with a clathrin heavy or light chain, the main components of the coat of coated vesicles and coated pits, and which also occurs in synaptic vesicles.
30277	maintenance of gastrointestinal epithelium	P	Protection of epithelial surfaces of the gastrointestinal tract from proteolytic and caustic digestive agents.
30278	regulation of ossification	P	Any process that modulates the frequency, rate or extent of bone formation.
30279	negative regulation of ossification	P	Any process that stops, prevents, or reduces the frequency, rate or extent of bone formation.
30280	structural constituent of epidermis	F	The action of a molecule that contributes to the structural integrity of an epidermal cutaneous structure.
30281	structural constituent of cutaneous appendage	F	The action of a molecule that contributes to the structural integrity of cutaneous epidermal structures such as hairs, scales, or feathers.
30282	bone mineralization	P	The deposition of hydroxyapatite, a form of calcium phosphate with the formula Ca10(PO4)6(OH)2, in bone tissue.
30283	testosterone dehydrogenase [NAD(P)] activity	F	Catalysis of the reaction: testosterone + NAD(P)+ = androst-4-ene-3,17-dione + NAD(P)H + H+.
30284	estrogen receptor activity	F	Combining with estrogen and transmitting the signal within the cell to trigger a change in cell activity or function.
30285	integral component of synaptic vesicle membrane	C	The component of the synaptic vesicle membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
30286	dynein complex	C	Any of several large complexes that contain two or three dynein heavy chains and several light chains, and have microtubule motor activity.
30287	cell wall-bounded periplasmic space	C	The region between the plasma membrane and the cell wall in organisms lacking an outer cell membrane such as yeast and Gram positive bacteria. The region is thinner than the equivalent in Gram negative bacteria.
30288	outer membrane-bounded periplasmic space	C	The region between the inner (cytoplasmic or plasma) membrane and outer membrane of organisms with two membranes such as Gram negative bacteria. These periplasmic spaces are relatively thick and contain a thin peptidoglycan layer (PGL), also referred to as a thin cell wall.
30289	protein phosphatase 4 complex	C	A protein serine/threonine phosphatase complex formed by the catalytic subunit of protein phosphatase 4 plus one or more regulatory subunits.
30290	sphingolipid activator protein activity	F	Any of a group of peptide cofactors of enzymes for the lysosomal degradation of sphingolipids. They stimulate various enzymes, including glucosylceramidase, galactosylceramidase, cerebroside-sulfatase, alpha-galactosidase, beta-galactosidase, and sphingomyelin phosphodiesterase.
30291	protein serine/threonine kinase inhibitor activity	F	Stops, prevents or reduces the activity of a protein serine/threonine kinase.
30292	protein tyrosine kinase inhibitor activity	F	Stops, prevents or reduces the activity of a protein tyrosine kinase.
30293	transmembrane receptor protein tyrosine kinase inhibitor activity	F	Stops, prevents or reduces the activity of a transmembrane receptor protein tyrosine kinase.
30294	receptor signaling protein tyrosine kinase inhibitor activity	F	Stops, prevents or reduces the activity of a receptor signaling protein tyrosine kinase.
30295	protein kinase activator activity	F	Binds to and increases the activity of a protein kinase, an enzyme which phosphorylates a protein.
30296	protein tyrosine kinase activator activity	F	Increases the activity of a protein tyrosine kinase, an enzyme which phosphorylates a tyrosyl phenolic group on a protein.
30297	transmembrane receptor protein tyrosine kinase activator activity	F	Binds to and increases the activity of a transmembrane receptor protein tyrosine kinase.
30298	receptor signaling protein tyrosine kinase activator activity	F	Binds to and increases the activity of a receptor signaling protein tyrosine kinase.
30299	intestinal cholesterol absorption	P	Uptake of cholesterol into the blood by absorption from the small intestine.
30300	regulation of intestinal cholesterol absorption	P	Any process that modulates the frequency, rate or extent of absorption of cholesterol into the blood, and the exclusion of other sterols from absorption.
30301	cholesterol transport	P	The directed movement of cholesterol, cholest-5-en-3-beta-ol, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
30302	deoxynucleotide transport	P	The directed movement of a deoxynucleotide, a deoxyribonucleoside in ester linkage to phosphate, commonly at the 5' position of deoxyribose, into, out of or within a cell.
30305	heparanase activity	F	Catalysis of the cleavage of heparan sulfate; can degrade both heparan sulfate and heparin glycosaminoglycan chains.
30306	ADP-ribosylation factor binding	F	Interacting selectively and non-covalently with ARF, ADP-ribosylation factor, a small monomeric cytosolic GTPase that, when bound to GTP, binds to the membranes of cells.
30307	positive regulation of cell growth	P	Any process that activates or increases the frequency, rate, extent or direction of cell growth.
30308	negative regulation of cell growth	P	Any process that stops, prevents, or reduces the frequency, rate, extent or direction of cell growth.
30309	poly-N-acetyllactosamine metabolic process	P	The chemical reactions and pathways involving poly-N-acetyllactosamine, a carbohydrate composed of N-acetyllactosamine repeats (Gal-beta-1,4-GlcNAc-beta-1,3)n.
30310	poly-N-acetyllactosamine catabolic process	P	The chemical reactions and pathways resulting in the breakdown of poly-N-acetyllactosamine, a carbohydrate composed of N-acetyllactosamine repeats (Gal-beta-1,4-GlcNAc-beta-1,3)n.
30311	poly-N-acetyllactosamine biosynthetic process	P	The chemical reactions and pathways resulting in the formation of poly-N-acetyllactosamine, a carbohydrate composed of N-acetyllactosamine repeats (Gal-beta-1,4-GlcNAc-beta-1,3)n.
30312	external encapsulating structure	C	A structure that lies outside the plasma membrane and surrounds the entire cell. This does not include the periplasmic space.
30313	cell envelope	C	An envelope that surrounds a bacterial cell and includes the cytoplasmic membrane and everything external, encompassing the periplasmic space, cell wall, and outer membrane if present.
30314	junctional membrane complex	C	Complex formed in muscle cells between the membrane of the sarcoplasmic reticulum and invaginations of the plasma membrane (T-tubules).
30315	T-tubule	C	Invagination of the plasma membrane of a muscle cell that extends inward from the cell surface around each myofibril. The ends of T-tubules make contact with the sarcoplasmic reticulum membrane.
30316	osteoclast differentiation	P	The process in which a relatively unspecialized monocyte acquires the specialized features of an osteoclast. An osteoclast is a specialized phagocytic cell associated with the absorption and removal of the mineralized matrix of bone tissue.
30317	flagellated sperm motility	P	Any process involved in the controlled movement of a flagellated sperm cell.
30318	melanocyte differentiation	P	The process in which a relatively unspecialized cell acquires specialized features of a melanocyte.
30320	cellular monovalent inorganic anion homeostasis	P	Any process involved in the maintenance of an internal steady state of monovalent inorganic anions at the level of a cell.
30321	transepithelial chloride transport	P	The directed movement of chloride ions from one side of an epithelium to the other.
30322	stabilization of membrane potential	P	The accomplishment of a non-fluctuating membrane potential, the electric potential existing across any membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane.
30323	respiratory tube development	P	The process whose specific outcome is the progression of the respiratory tube over time, from its formation to the mature structure. The respiratory tube is assumed to mean any tube in the respiratory tract.
30324	lung development	P	The process whose specific outcome is the progression of the lung over time, from its formation to the mature structure. In all air-breathing vertebrates the lungs are developed from the ventral wall of the oesophagus as a pouch which divides into two sacs. In amphibians and many reptiles the lungs retain very nearly this primitive sac-like character, but in the higher forms the connection with the esophagus becomes elongated into the windpipe and the inner walls of the sacs become more and more divided, until, in the mammals, the air spaces become minutely divided into tubes ending in small air cells, in the walls of which the blood circulates in a fine network of capillaries. In mammals the lungs are more or less divided into lobes, and each lung occupies a separate cavity in the thorax.
30325	adrenal gland development	P	The process whose specific outcome is the progression of the adrenal gland over time, from its formation to the mature structure. This gland can either be a discrete structure located bilaterally above each kidney, or a cluster of cells in the head kidney that perform the functions of the adrenal gland. In either case, this organ consists of two cells types, aminergic chromaffin cells and steroidogenic cortical cells.
30326	embryonic limb morphogenesis	P	The process, occurring in the embryo, by which the anatomical structures of the limb are generated and organized. A limb is an appendage of an animal used for locomotion or grasping.
30327	prenylated protein catabolic process	P	The chemical reactions and pathways resulting in the breakdown of prenylated proteins.
30328	prenylcysteine catabolic process	P	The chemical reactions and pathways resulting in the breakdown of prenylcysteine, 3-methyl-2-buten-1-yl-cysteine, a derivative of the amino acid cysteine formed by the covalent addition of a prenyl residue.
30329	prenylcysteine metabolic process	P	The chemical reactions and pathways involving prenylcysteine, 3-methyl-2-buten-1-yl-cysteine, a derivative of the amino acid cysteine formed by the covalent addition of a prenyl residue.
30330	DNA damage response, signal transduction by p53 class mediator	P	A cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage.
30331	estrogen receptor binding	F	Interacting selectively and non-covalently with an estrogen receptor.
30332	cyclin binding	F	Interacting selectively and non-covalently with cyclins, proteins whose levels in a cell varies markedly during the cell cycle, rising steadily until mitosis, then falling abruptly to zero. As cyclins reach a threshold level, they are thought to drive cells into G2 phase and thus to mitosis.
30334	regulation of cell migration	P	Any process that modulates the frequency, rate or extent of cell migration.
30335	positive regulation of cell migration	P	Any process that activates or increases the frequency, rate or extent of cell migration.
30336	negative regulation of cell migration	P	Any process that stops, prevents, or reduces the frequency, rate or extent of cell migration.
30337	DNA polymerase processivity factor activity	F	An enzyme regulator activity that increases the processivity of polymerization by DNA polymerase, by allowing the polymerase to move rapidly along DNA while remaining topologically bound to it.
30338	CMP-N-acetylneuraminate monooxygenase activity	F	Catalysis of the reaction: CMP-N-acetylneuraminate + NADPH + H+ + O2 = CMP-N-glycoloylneuraminate + NADP+ + H2O.
30339	fatty-acyl-ethyl-ester synthase activity	F	Catalysis of the reaction: a long-chain-acyl ethyl ester + H2O = a long-chain carboxylic acid + ethanol.
30340	hyaluronate lyase activity	F	Catalysis of the reaction: hyaluronate = n 3-(4-deoxy-beta-D-gluc-4-enuronosyl)-N-acetyl-D-glucosamine.
30341	chondroitin AC lyase activity	F	Catalysis of the eliminative degradation of polysaccharides containing 1,4-beta-D-hexosaminyl and 1,3-beta-D-glucuronosyl linkages to disaccharides containing 4-deoxy-beta-D-gluc-4-enuronosyl groups.
30342	1-alpha,25-dihydroxyvitamin D3 24-hydroxylase activity	F	Catalysis of the hydroxylation of C-24 of 1-alpha,25-hydroxycholecalciferol (25-hydroxyvitamin D3; calcitriol).
30343	vitamin D3 25-hydroxylase activity	F	Catalysis of the reaction: vitamin D3 + NADPH + H+ + O2 = calcidiol + NADP+ + H2O.
30345	structural constituent of tooth enamel	F	The action of a molecule that contributes to the structural integrity of tooth enamel.
30346	protein phosphatase 2B binding	F	Interacting selectively and non-covalently with the enzyme protein phosphatase 2B.
30348	syntaxin-3 binding	F	Interacting selectively and non-covalently with the SNAP receptor syntaxin-3.
30350	iron-responsive element binding	F	Interacting selectively and non-covalently with the iron-responsive element, a regulatory sequence found in the 5'- and 3'-untranslated regions of mRNAs encoding many iron-binding proteins.
30351	inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase activity	F	Catalysis of the reaction: inositol-1,3,4,5,6-pentakisphosphate + H2O = inositol-1,4,5,6-tetrakisphosphate + phosphate.
30352	inositol-1,4,5,6-tetrakisphosphate 6-phosphatase activity	F	Catalysis of the reaction: inositol-1,4,5,6-tetrakisphosphate + H2O = inositol-1,4,5-trisphosphate + phosphate.
30353	fibroblast growth factor receptor antagonist activity	F	Interacts with the fibroblast growth factor receptor to reduce the action of another ligand, the agonist.
30354	melanin-concentrating hormone activity	F	The action characteristic of melanin-concentrating hormone, a cyclic peptide hormone that, upon receptor binding, induces melanin aggregation in melanocytes, and is also involved in regulating food intake and energy balance in mammals.
30366	molybdopterin synthase activity	F	Catalysis of the conversion of precursor Z to molybdopterin, the final step in molybdopterin biosynthesis.
30367	interleukin-17 receptor binding	F	Interacting selectively and non-covalently with the interleukin-17 receptor.
30368	interleukin-17 receptor activity	F	Combining with any member of the interleukin-17 family of cytokines and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
30369	ICAM-3 receptor activity	F	Combining with ICAM-3, intercellular adhesion molecule 3, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. ICAM-3, or CD50, are constitutively expressed on monocytes, granulocytes and lymphocytes; on physiological stimulation, they become transiently phosphorylated on serine residues.
30370	intercellular adhesion molecule-3 receptor binding	F	Interacting selectively and non-covalently with receptors for intercellular adhesion molecule-3 (ICAM-3), such as DC-SIGN and LFA-1.
30371	translation repressor activity	F	Antagonizes ribosome-mediated translation of mRNA into a polypeptide.
30372	high molecular weight B cell growth factor receptor binding	F	Interacting selectively and non-covalently with the high molecular weight B cell growth factor receptor.
30373	high molecular weight B cell growth factor receptor activity	F	Combining with a high molecular weight B cell growth factor and transmitting the signal to initiate a change in cell activity.
30374	ligand-dependent nuclear receptor transcription coactivator activity	F	The function of a transcription cofactor that activates transcription in conjuction with a ligand-dependent nuclear receptor from a RNA polymerase II promoter; does not bind DNA itself.
30375	thyroid hormone receptor coactivator activity	F	The function of a transcription cofactor that activates transcription in conjunction with a thyroid hormone-dependent nuclear receptor from a RNA polymerase II promoter; does not bind DNA itself.
30377	urokinase plasminogen activator receptor activity	F	Combining with the urokinase plasminogen activator to initiate a change in cell activity.
30378	serine racemase activity	F	Catalysis of the synthesis of free D-serine from L-serine.
30379	neurotensin receptor activity, non-G-protein coupled	F	Combining with neurotensin, a neuropeptide active in the central and peripheral nervous system in mammals, and transmitting the signal from one side of the membrane to the other by a mechanism independent of coupling to G proteins.
30380	interleukin-17E receptor binding	F	Interacting selectively and non-covalently with the interleukin-17E receptor.
30381	chorion-containing eggshell pattern formation	P	The regionalization process that gives rise to the structural pattern of a chorion-containing eggshell such as those found in insects.
30382	sperm mitochondrion organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of sperm mitochondria; the process in which they take on their characteristic morphology; they are flattened, elongated, and arranged circumferentially into a tight helical coil around the tail-dense fibers of the mature sperm.
30385	ferredoxin:thioredoxin reductase activity	F	Catalysis of the two-electron reduction of the disulfide of thioredoxins with electrons from ferredoxin involving a 4Fe-4S cluster and an adjacent active-site disulfide.
30386	ferredoxin:thioredoxin reductase complex	C	A protein complex that possesses ferredoxin:thioredoxin reductase activity.
30387	fructosamine-3-kinase activity	F	Catalysis of the phosphorylation of fructosamine to form fructosamine-3-kinase.
30388	fructose 1,6-bisphosphate metabolic process	P	The chemical reactions and pathways involving fructose 1,6-bisphosphate, also known as FBP. The D enantiomer is a metabolic intermediate in glycolysis and gluconeogenesis.
30389	fructosamine metabolic process	P	The chemical reactions and pathways involving fructosamine, a fructose molecule containing an amino group in place of a hydroxyl group.
30391	fructosamine biosynthetic process	P	The chemical reactions and pathways resulting in the formation of fructosamine, a fructose molecule containing an amino group in place of a hydroxyl group.
30392	fructosamine catabolic process	P	The chemical reactions and pathways resulting in the breakdown of fructosamine, a fructose molecule containing an amino group in place of a hydroxyl group.
30393	fructoselysine metabolic process	P	The chemical reactions and pathways involving fructoselysine, a fructose molecule containing a lysine group in place of a hydroxyl group.
30394	fructoseglycine metabolic process	P	The chemical reactions and pathways involving fructoseglycine, a fructose molecule containing a glycine group in place of a hydroxyl group.
30395	lactose binding	F	Interacting selectively and non-covalently with lactose, a disaccharide of glucose and galactose, the carbohydrate of milk.
30397	membrane disassembly	P	The controlled breakdown of any cell membrane in the context of a normal process such as autophagy.
30398	peroxisomal membrane disassembly	P	The controlled breakdown of the membranes of cargo-carrying vesicles formed during peroxisome degradation.
30399	autophagosome membrane disassembly	P	The controlled breakdown of the membranes of autophagosomes.
30407	formimidoyltransferase activity	F	Catalysis of the transfer of a formimino group from 5-formimidoyltetrahydrofolate to an acceptor molecule such as an amino acid.
30408	glycine formimidoyltransferase activity	F	Catalysis of the reaction: 5-formimidoyltetrahydrofolate + glycine = (6S)-5,6,7,8-tetrahydrofolate + N-formimidoylglycine.
30409	glutamate formimidoyltransferase activity	F	Catalysis of the reaction: 5-formimidoyltetrahydrofolate + L-glutamate = tetrahydrofolate + N-formimidoyl-L-glutamate.
30410	nicotianamine synthase activity	F	Catalysis of the reaction: 3 S-adenosyl-L-methionine(1+) = 3 S-methyl-5'-thioadenosine + 3 H(+) + nicotianamine.
30411	scytalone dehydratase activity	F	Catalysis of the reaction: scytalone = 1,3,8-trihydroxynaphthalene + H(2)O.
30412	formimidoyltetrahydrofolate cyclodeaminase activity	F	Catalysis of the reaction: 5-formimidoyltetrahydrofolate + 2 H(+) = 5,10-methenyltetrahydrofolate + NH(4)(+).
30413	competence pheromone activity	F	A small peptide excreted by a naturally transformable bacterium (e.g. Bacillus subtilis) that transmits a signal required for the establishment of competence.
30414	peptidase inhibitor activity	F	Stops, prevents or reduces the activity of a peptidase, any enzyme that catalyzes the hydrolysis peptide bonds.
30416	methylamine metabolic process	P	The chemical reactions and pathways involving methylamine (CH3NH2).
30417	nicotianamine metabolic process	P	The chemical reactions and pathways involving nicotianamine, 2(S),3'2(S),3''(S)-N-(N-(3-amino-3-carboxypropyl)-3-amino-3-carboxypropyl)-azetidine-2-carboxylic acid.
30418	nicotianamine biosynthetic process	P	The chemical reactions and pathways resulting in the formation of nicotianamine, 2(S),3'2(S),3''(S)-N-(N-(3-amino-3-carboxypropyl)-3-amino-3-carboxypropyl)-azetidine-2-carboxylic acid.
30419	nicotianamine catabolic process	P	The chemical reactions and pathways resulting in the breakdown of nicotianamine, 2(S),3'2(S),3''(S)-N-(N-(3-amino-3-carboxypropyl)-3-amino-3-carboxypropyl)-azetidine-2-carboxylic acid.
30420	establishment of competence for transformation	P	The process in which a naturally transformable bacterium acquires the ability to take up exogenous DNA. This term should be applied only to naturally transformable bacteria, and should not be used in the context of artificially induced bacterial transformation.
30421	defecation	P	The expulsion of feces from the rectum.
30422	production of siRNA involved in RNA interference	P	Cleavage of double-stranded RNA to form small interfering RNA molecules (siRNAs) of 21-23 nucleotides, in the context of RNA interference.
30423	targeting of mRNA for destruction involved in RNA interference	P	The process in which small interfering RNAs target cognate mRNA molecules for degradation.
30424	axon	C	The long process of a neuron that conducts nerve impulses, usually away from the cell body to the terminals and varicosities, which are sites of storage and release of neurotransmitter.
30425	dendrite	C	A neuron projection that has a short, tapering, often branched, morphology, receives and integrates signals from other neurons or from sensory stimuli, and conducts a nerve impulse towards the axon or the cell body. In most neurons, the impulse is conveyed from dendrites to axon via the cell body, but in some types of unipolar neuron, the impulse does not travel via the cell body.
30426	growth cone	C	The migrating motile tip of a growing nerve cell axon or dendrite.
30427	site of polarized growth	C	Any part of a cell where non-isotropic growth takes place.
30428	cell septum	C	A structure composed of peptidoglycan and often chitin in addition to other materials. It usually forms perpendicular to the long axis of a cell or hypha and grows centripetally from the cell wall to the center of the cell and often functions in the compartmentalization of a cell into two daughter cells.
30429	kynureninase activity	F	Catalysis of the reaction: L-kynurenine + H2O = anthranilate + L-alanine.
30430	host cell cytoplasm	C	The cytoplasm of a host cell.
30431	sleep	P	Any process in which an organism enters and maintains a periodic, readily reversible state of reduced awareness and metabolic activity. Usually accompanied by physical relaxation, the onset of sleep in humans and other mammals is marked by a change in the electrical activity of the brain.
30432	peristalsis	P	A wavelike sequence of involuntary muscular contraction and relaxation that passes along a tubelike structure, such as the intestine, impelling the contents onwards.
30433	ER-associated ubiquitin-dependent protein catabolic process	P	The chemical reactions and pathways resulting in the breakdown of proteins transported from the endoplasmic reticulum and targeted to cytoplasmic proteasomes for degradation. This process acts on misfolded proteins as well as in the regulated degradation of correctly folded proteins.
30435	sporulation resulting in formation of a cellular spore	P	The process in which a relatively unspecialized cell acquires the specialized features of a cellular spore, a cell form that can be used for dissemination, for survival of adverse conditions because of its heat and dessication resistance, and/or for reproduction.
30436	asexual sporulation	P	The formation of spores derived from the products of mitosis. Examples of this process are found in Bacterial species.
30437	ascospore formation	P	The process in which cells that are products of meiosis acquire the specialized features of ascospores. Ascospores are generally found in clusters of four or eight spores within a single mother cell, the ascus, and are characteristic of the ascomycete fungi (phylum Ascomycota).
30445	yeast-form cell wall	C	The wall surrounding a cell of a dimorphic fungus growing in the single-cell budding yeast form, in contrast to the filamentous or hyphal form.
30446	hyphal cell wall	C	The cell wall surrounding a fungal hypha.
30447	filamentous growth	P	The process in which a multicellular organism, a unicellular organism or a group of unicellular organisms grow in a threadlike, filamentous shape.
30448	hyphal growth	P	Growth of fungi as threadlike, tubular structures that may contain multiple nuclei and may or may not be divided internally by septa, or cross-walls.
30449	regulation of complement activation	P	Any process that modulates the frequency, rate or extent of complement activation.
30450	regulation of complement activation, classical pathway	P	Any process that modulates the frequency, rate or extent of the classical pathway of complement activation.
30451	regulation of complement activation, alternative pathway	P	Any process that modulates the frequency, rate or extent of the alternative pathway of complement activation.
30466	chromatin silencing at silent mating-type cassette	P	Repression of transcription at silent mating-type loci by alteration of the structure of chromatin.
30472	mitotic spindle organization in nucleus	P	A process resulting in the assembly, arrangement of constituent parts, or disassembly of the microtubule spindle in the nucleus. The process occurs during a mitotic cell cycle and takes place at the cellular level.
30473	nuclear migration along microtubule	P	The directed movement of the nucleus along microtubules within the cell, mediated by motor proteins.
30474	spindle pole body duplication	P	Construction of a new spindle pole body.
30476	ascospore wall assembly	P	The aggregation, arrangement and bonding together of a set of components to form an ascospore wall. During sporulation in Ascomycota, each ascospore nucleus becomes surrounded by a specialized spore wall, formed by deposition of spore wall components in the lumenal space between the outer and inner leaflets of the prospore membrane. An example of this process is found in Saccharomyces cerevisiae.
30478	actin cap	C	Polarized accumulation of cytoskeletal proteins (including F-actin) and regulatory proteins in a cell. An example of this is the actin cap found in Saccharomyces cerevisiae.
30479	actin cortical patch	C	An endocytic patch that consists of an actin-containing structure found at the plasma membrane in cells; formed of networks of branched actin filaments that lie just beneath the plasma membrane and assemble, move, and disassemble rapidly. An example of this is the actin cortical patch found in Saccharomyces cerevisiae.
30485	smooth muscle contractile fiber	C	The contractile fiber of smooth muscle cells.
30486	smooth muscle dense body	C	Electron-dense region associated with a smooth muscle contractile fiber.
30487	inositol-4,5-bisphosphate 5-phosphatase activity	F	Catalysis of the reaction: 1D-myo-inositol 4,5-bisphosphate + H2O = 1D-myo-inositol 4-phosphate + phosphate.
30488	tRNA methylation	P	The posttranscriptional addition of methyl groups to specific residues in a tRNA molecule.
30490	maturation of SSU-rRNA	P	Any process involved in the maturation of a precursor Small SubUnit (SSU) ribosomal RNA (rRNA) molecule into a mature SSU-rRNA molecule.
30491	heteroduplex formation	P	The formation of a stable duplex DNA that contains one strand from each of the two recombining DNA molecules.
30492	hemoglobin binding	F	Interacting selectively and non-covalently with hemoglobin, an oxygen carrying, conjugated protein containing four heme groups and globin.
30493	bacteriochlorophyll metabolic process	P	The chemical reactions and pathways involving a bacteriochlorophyll, any of the chlorophylls of photosynthetic bacteria. They differ structurally from the chlorophylls of higher plants.
30494	bacteriochlorophyll biosynthetic process	P	The chemical reactions and pathways resulting in the formation of a bacteriochlorophyll, any of the chlorophylls of photosynthetic bacteria. They differ structurally from the chlorophylls of higher plants.
30495	bacteriochlorophyll catabolic process	P	The chemical reactions and pathways resulting in the breakdown of bacteriochlorophyll, any of the chlorophylls of photosynthetic bacteria. They differ structurally from the chlorophylls of higher plants.
30496	midbody	C	A thin cytoplasmic bridge formed between daughter cells at the end of cytokinesis. The midbody forms where the contractile ring constricts, and may persist for some time before finally breaking to complete cytokinesis.
30497	fatty acid elongation	P	The elongation of a fatty acid chain by the sequential addition of two-carbon units.
30500	regulation of bone mineralization	P	Any process that modulates the frequency, rate or extent of bone mineralization.
30501	positive regulation of bone mineralization	P	Any process that activates or increases the frequency, rate or extent of bone mineralization.
30502	negative regulation of bone mineralization	P	Any process that stops, prevents, or reduces the frequency, rate or extent of bone mineralization.
30504	inorganic diphosphate transmembrane transporter activity	F	Enables the transfer of inorganic diphosphate across a membrane.
30505	inorganic diphosphate transport	P	The directed movement of inorganic diphosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
30506	ankyrin binding	F	Interacting selectively and non-covalently with ankyrin, a 200 kDa cytoskeletal protein that attaches other cytoskeletal proteins to integral membrane proteins.
30507	spectrin binding	F	Interacting selectively and non-covalently with spectrin, a protein that is the major constituent of the erythrocyte cytoskeletal network. It associates with band 4.1 (see band protein) and actin to form the cytoskeletal superstructure of the erythrocyte plasma membrane. It is composed of nonhomologous chains, alpha and beta, which aggregate side-to-side in an antiparallel fashion to form dimers, tetramers, and higher polymers.
30509	BMP signaling pathway	P	A series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.
30510	regulation of BMP signaling pathway	P	Any process that modulates the frequency, rate or extent of the activity of any BMP receptor signaling pathway.
30511	positive regulation of transforming growth factor beta receptor signaling pathway	P	Any process that activates or increases the frequency, rate or extent of TGF-beta receptor signaling pathway activity.
30512	negative regulation of transforming growth factor beta receptor signaling pathway	P	Any process that stops, prevents, or reduces the frequency, rate or extent of any TGF-beta receptor signaling pathway.
30513	positive regulation of BMP signaling pathway	P	Any process that activates or increases the frequency, rate or extent of BMP signaling pathway activity.
30514	negative regulation of BMP signaling pathway	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the BMP signaling pathway.
30515	snoRNA binding	F	Interacting selectively and non-covalently with small nucleolar RNA.
30516	regulation of axon extension	P	Any process that modulates the rate, direction or extent of axon extension.
30517	negative regulation of axon extension	P	Any process that stops, prevents, or reduces the frequency, rate or extent of axon outgrowth.
30518	intracellular steroid hormone receptor signaling pathway	P	A series of molecular signals generated as a consequence of a intracellular steroid hormone receptor binding to one of its physiological ligands.
30519	snoRNP binding	F	Interacting selectively and non-covalently with any part of a small nucleolar ribonucleoprotein particle.
30520	intracellular estrogen receptor signaling pathway	P	Any series of molecular signals generated as a consequence of an intracellular estrogen receptor binding to one of its physiological ligands. The pathway begins with receptor-ligand binding, and ends with regulation of a downstream cellular process (e.g. transcription).
30521	androgen receptor signaling pathway	P	Any series of molecular signals generated as a consequence of an androgen binding to its receptor.
30522	intracellular receptor signaling pathway	P	Any series of molecular signals initiated by a ligand binding to an receptor located within a cell.
30523	dihydrolipoamide S-acyltransferase activity	F	Catalysis of the reaction: acyl-CoA + dihydrolipoamide = CoA + S-acyldihydrolipoamide.
30526	granulocyte macrophage colony-stimulating factor receptor complex	C	The heterodimeric receptor for granulocyte macrophage colony-stimulating factor.
30527	structural constituent of chromatin	F	The action of a molecule that contributes to the structural integrity of chromatin.
30529	intracellular ribonucleoprotein complex	C	An intracellular macromolecular complex containing both protein and RNA molecules.
30532	small nuclear ribonucleoprotein complex	C	A complex composed of RNA of the small nuclear RNA (snRNA) class and protein, found in the nucleus of a eukaryotic cell. These are typically named after the snRNA(s) they contain, e.g. U1 snRNP or U4/U6 snRNP. Many, but not all, of these complexes are involved in splicing of nuclear mRNAs.
30533	triplet codon-amino acid adaptor activity	F	The codon binding activity of a tRNA that positions an activated amino acid, mediating its insertion at the correct point in the sequence of a nascent polypeptide chain during protein synthesis.
30534	adult behavior	P	Behavior in a fully developed and mature organism.
30536	larval feeding behavior	P	Feeding behavior in a larval (immature) organism.
30537	larval behavior	P	Behavior in a larval form of an organism, an immature organism that must undergo metamorphosis to assume adult characteristics.
30538	embryonic genitalia morphogenesis	P	The process, occurring in the embryo, by which the anatomical structures of the genitalia are generated and organized.
30539	male genitalia development	P	The process whose specific outcome is the progression of the male genitalia over time, from its formation to the mature structure.
30540	female genitalia development	P	The process whose specific outcome is the progression of the female genitalia over time, from formation to the mature structure.
30541	plasmid partitioning	P	Any process in which plasmids are segregated or distributed into daughter cells upon cell division.
30543	2-micrometer plasmid partitioning	P	The process in which copies of the 2-micrometer plasmid, found in fungi such as Saccharomyces, are distributed to daughter cells upon cell division.
30544	Hsp70 protein binding	F	Interacting selectively and non-covalently with Hsp70 proteins, any of a group of heat shock proteins around 70kDa in size.
30545	receptor regulator activity	F	The function of interacting (directly or indirectly) with receptors such that the proportion of receptors in the active form is changed.
30546	receptor activator activity	F	The function of interacting (directly or indirectly) with receptors such that the proportion of receptors in the active form is increased.
30547	receptor inhibitor activity	F	The function of interacting (directly or indirectly) with receptors such that the proportion of receptors in the active form is decreased.
30548	acetylcholine receptor regulator activity	F	Interacting (directly or indirectly) with acetylcholine receptors such that the proportion of receptors in the active form is changed.
30549	acetylcholine receptor activator activity	F	Interacting (directly or indirectly) with acetylcholine receptors such that the proportion of receptors in the active form is increased.
30550	acetylcholine receptor inhibitor activity	F	Interacting (directly or indirectly) with acetylcholine receptors such that the proportion of receptors in the active form is decreased.
30551	cyclic nucleotide binding	F	Interacting selectively and non-covalently with a cyclic nucleotide, a nucleotide in which the phosphate group is in diester linkage to two positions on the sugar residue.
30552	cAMP binding	F	Interacting selectively and non-covalently with cAMP, the nucleotide cyclic AMP (adenosine 3',5'-cyclophosphate).
30553	cGMP binding	F	Interacting selectively and non-covalently with cGMP, the nucleotide cyclic GMP (guanosine 3',5'-cyclophosphate).
30554	adenyl nucleotide binding	F	Interacting selectively and non-covalently with adenyl nucleotides, any compound consisting of adenosine esterified with (ortho)phosphate.
30555	RNA modification guide activity	F	Specifies the site of a posttranscriptional modification in an RNA molecule by base pairing with a short sequence around the target residue.
30556	rRNA modification guide activity	F	Specifies the site of a posttranscriptional modification in an rRNA molecule by base pairing with a short sequence around the target residue.
30557	tRNA modification guide activity	F	Specifies the site of a posttranscriptional modification in a tRNA molecule by base pairing with a short sequence around the target residue.
30558	RNA pseudouridylation guide activity	F	Specifies the site of pseudouridylation in an RNA molecule by base pairing with a short sequence around the target residue.
30559	rRNA pseudouridylation guide activity	F	Specifies the site of pseudouridylation in an rRNA molecule by base pairing with a short sequence around the target residue.
30560	tRNA pseudouridylation guide activity	F	Specifies the site of pseudouridylation in a tRNA molecule by base pairing with a short sequence around the target residue.
30561	RNA 2'-O-ribose methylation guide activity	F	Specifies the site of 2'-O-ribose methylation in an RNA molecule by base pairing with a short sequence around the target residue.
30562	rRNA 2'-O-ribose methylation guide activity	F	Specifies the site of 2'-O-ribose methylation in an rRNA molecule by base pairing with a short sequence around the target residue.
30563	snRNA 2'-O-ribose methylation guide activity	F	Activity that provides specificity to a methylase by using base complementarity to guide site-specific 2'-O-ribose methylations to a small nuclear RNA molecule.
30564	tRNA 2'-O-ribose methylation guide activity	F	Specifies the site of 2'-O-ribose methylation in a tRNA molecule by base pairing with a short sequence around the target residue.
30565	snRNA pseudouridylation guide activity	F	Activity that provides specificity to a pseudouridine synthetase by using base complementarity to guide site-specific pseudouridylations to a small nuclear RNA molecule.
30566	snRNA modification guide activity	F	Specifies the site of a posttranscriptional modification in an snRNA molecule by base pairing with a short sequence around the target residue.
30570	pectate lyase activity	F	Catalysis of the reaction: a pectate = a pectate + a pectate oligosaccharide with 4-(4-deoxy-alpha-D-galact-4-enuronosyl)-D-galacturonate end. This reaction is the eliminative cleavage of pectate to give oligosaccharides with 4-deoxy-alpha-D-gluc-4-enuronosyl groups at their non-reducing ends.
30572	phosphatidyltransferase activity	F	Catalysis of the reaction involving the transfer of a phosphatidate (otherwise known as diacylglycerol 3-phosphosphate) group.
30573	bile acid catabolic process	P	The chemical reactions and pathways resulting in the breakdown of bile acids, any of a group of steroid carboxylic acids occurring in bile.
30574	collagen catabolic process	P	The proteolytic chemical reactions and pathways resulting in the breakdown of collagen in the extracellular matrix, usually carried out by proteases secreted by nearby cells.
30575	nuclear body organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of any of the extra-nucleolar nuclear domains usually visualized by confocal microscopy and fluorescent antibodies to specific proteins.
30576	Cajal body organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of Cajal bodies, nuclear bodies that appear ultrastructurally as a tangle of coiled, electron-dense threads roughly 0.5 micrometers in diameter and are enriched in ribonucleoproteins, and certain general RNA polymerase II transcription factors.
30577	Lands organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of Lands, a class of nuclear body that react against SP140 auto-antibodies.
30578	PML body organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of PML bodies, a class of nuclear body; they react against SP100 auto-antibodies (PML = promyelocytic leukemia).
30579	ubiquitin-dependent SMAD protein catabolic process	P	The chemical reactions and pathways resulting in the breakdown of SMAD signaling proteins by ubiquitination and targeting to the proteasome.
30580	quinone cofactor methyltransferase activity	F	Catalysis of the transfer of a methyl group from S-adenosylmethionine during the synthesis of quinone cofactors such as ubiquinone (coenzyme Q), menaquinone (vitamin K2), plastoquinone and phylloquinone (vitamin K1).
30581	symbiont intracellular protein transport in host	P	The directed movement of a symbiont's proteins within a cell of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
30582	reproductive fruiting body development	P	The process whose specific outcome is the progression of a reproductive fruiting body over time, from its formation to the mature structure. A reproductive fruiting body is a multicellular reproductive structure that contains spores.
30583	myxococcal fruiting body development	P	The process whose specific outcome is the progression of the myxococcal fruiting body over time, from its formation to the mature structure. The process begins when myxococci respond to a lack of nutrients in the environment and ends when the myxococcal fruiting body is a mature structure.
30584	sporocarp development	P	The process whose specific outcome is the progression of a sporocarp over time, from its formation to the mature structure. The sporocarp is a spore bearing fruiting body organ. An example of this process is found in the Fungal species Coprinopsis cinerea.
30585	phosphoenolpyruvate carboxykinase (diphosphate) activity	F	Catalysis of the reaction: diphosphate + oxaloacetate = CO(2) + phosphate + phosphoenolpyruvate.
30586	[methionine synthase] reductase activity	F	Catalysis of the reaction: [methionine synthase]-cob(II)alamin + NADPH + H+ + S-adenosyl methionine = [methionine synthase]-methylcob(I)alamin + S-adenosylhomocysteine + NADP+.
30587	sorocarp development	P	The process whose specific outcome is the progression of the sorocarp over time, from its formation to the mature structure. The process begins with the aggregation of individual cells and ends with the mature sorocarp. The sorocarp is a structure containing a spore-bearing sorus that sits on top of a stalk. An example of this process is found in Dictyostelium discoideum.
30588	pseudocleavage	P	Partial constriction of the cytoplasm of an embryo to form a furrow that resembles a cleavage furrow but does not complete cytokinesis.
30589	pseudocleavage involved in syncytial blastoderm formation	P	Formation of furrows in the cytoplasm between nuclei during cell cycles in embryos that contribute to the formation of the syncytial blastoderm. An example of this process is found in Drosophila melanogaster.
30590	first cell cycle pseudocleavage	P	A process that occurs during the first cell cycle in an embryo, in which anterior cortical contractions culminate in a single partial constriction of the embryo called the pseudocleavage furrow. An example of this process is found in nematode worms.
30591	NAD DNA ADP-ribosyltransferase activity	F	Catalysis of the transfer of the ADP-ribose group of NAD+ to the amino group at N2 of 2'-deoxyguanosine to yield N2-(alpha-ADP-ribos-1-yl)-2'-deoxyguanosine and its beta form.
30592	DNA ADP-ribosylation	P	The covalent attachment of an ADP-ribosyl group to the amino group at N2 of a 2'-deoxyguanosine residue in double-stranded DNA.
30593	neutrophil chemotaxis	P	The directed movement of a neutrophil cell, the most numerous polymorphonuclear leukocyte found in the blood, in response to an external stimulus, usually an infection or wounding.
30594	neurotransmitter receptor activity	F	Combining with a neurotransmitter and transmitting the signal to initiate a change in cell activity.
30595	leukocyte chemotaxis	P	The movement of a leukocyte in response to an external stimulus.
30596	alpha-L-rhamnosidase activity	F	Catalysis of the hydrolysis of terminal non-reducing alpha-L-rhamnose residues in alpha-L-rhamnosides.
30597	RNA glycosylase activity	F	Catalysis of the hydrolysis of N-glycosidic bonds in an RNA molecule.
30598	rRNA N-glycosylase activity	F	Catalysis of the hydrolysis of the N-glycosylic bond at A-4324 in 28S rRNA from rat ribosomes or corresponding sites in 28S RNA from other species.
30599	pectinesterase activity	F	Catalysis of the reaction: pectin + n H2O = n methanol + pectate.
30600	feruloyl esterase activity	F	Catalysis of the reaction: feruloyl-polysaccharide + H2O = ferulate + polysaccharide.
30603	oxaloacetase activity	F	Catalysis of the reaction: H(2)O + oxaloacetate = acetate + H(+) + oxalate.
30604	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity	F	Catalysis of the reaction: 2-C-methyl-D-erythritol 4-phosphate + NADP(+) = 1-deoxy-D-xylulose 5-phosphate + H(+) + NADPH.
30611	arsenate reductase activity	F	Catalysis of the interconversion of arsenate and arsenite.
30612	arsenate reductase (thioredoxin) activity	F	Catalysis of the reaction: arsenate + thioredoxin = arsenite + thioredoxin disulfide. Thioredoxin disulfide is also known as oxidized thioredoxin.
30613	oxidoreductase activity, acting on phosphorus or arsenic in donors	F	Catalysis of an oxidation-reduction (redox) reaction in which a phosphorus- or arsenic-containing group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.
30614	oxidoreductase activity, acting on phosphorus or arsenic in donors, disulfide as acceptor	F	Catalysis of an oxidation-reduction (redox) reaction in which a phosphorus- or arsenic-containing group acts as a hydrogen or electron donor and reduces a disulfide.
30616	transforming growth factor beta receptor, common-partner cytoplasmic mediator activity	F	A TGF-beta cytoplasmic mediator that forms a complex with a phosphorylated pathway-specific mediator. The heterocomplex translocates to the nucleus to regulate transcription.
30617	transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity	F	A TGF-beta cytoplasmic mediator that inhibits the signaling function of common-partner and pathway-specific mediators.
30618	transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity	F	A TGF-beta cytoplasmic mediator that is phosphorylated by a TGFbeta receptor and complexes with a common-partner mediator. The- heterocomplex translocates to the nucleus to regulate transcription.
30619	U1 snRNA binding	F	Interacting selectively and non-covalently with the U1 small nuclear RNA (U1 snRNA).
30620	U2 snRNA binding	F	Interacting selectively and non-covalently with the U2 small nuclear RNA (U2 snRNA).
30621	U4 snRNA binding	F	Interacting selectively and non-covalently with the U4 small nuclear RNA (U4 snRNA).
30622	U4atac snRNA binding	F	Interacting selectively and non-covalently with the U4atac small nuclear RNA (U4atac snRNA).
30623	U5 snRNA binding	F	Interacting selectively and non-covalently with the U5 small nuclear RNA (U5 snRNA).
30624	U6atac snRNA binding	F	Interacting selectively and non-covalently with the U6atac small nuclear RNA (U6atac snRNA).
30625	U11 snRNA binding	F	Interacting selectively and non-covalently with the U11 small nuclear RNA (U11 snRNA).
30626	U12 snRNA binding	F	Interacting selectively and non-covalently with the U12 small nuclear RNA (U12 snRNA).
30627	pre-mRNA 5'-splice site binding	F	Interacting selectively and non-covalently with the pre-mRNA 5' splice site sequence.
30628	pre-mRNA 3'-splice site binding	F	Interacting selectively and non-covalently with the pre-mRNA 3' splice site sequence.
30629	U6 snRNA 3'-end binding	F	Interacting selectively and non-covalently with the 3' end of the U6 small nuclear RNA (U6 snRNA).
30631	pyrrolysine incorporation	P	The incorporation of pyrrolysine, also known as lysine methylamine methyltransferase cofactor adduct, into a peptide; uses a special tRNA that recognizes the UAG codon as a modified lysine, rather than as a termination codon. Pyrrolysine may be synthesized as a free amino acid or synthesized from a lysine charged tRNA before its incorporation; it is not a posttranslational modification of peptidyl-lysine; this modification is found in several Methanosarcina methylamine methyltransferases.
30632	D-alanine biosynthetic process	P	The chemical reactions and pathways resulting in the formation of D-alanine, the D-enantiomer of the amino acid alanine, i.e (2R)-2-aminopropanoic acid.
30633	D-alanine family amino acid catabolic process	P	The chemical reactions and pathways resulting in the breakdown of D-alanine and related amino acids.
30634	carbon fixation by acetyl-CoA pathway	P	A pathway of carbon dioxide fixation in which one molecule of acetyl-CoA is completely synthesized from two molecules of carbon dioxide (CO2).
30638	polyketide metabolic process	P	The chemical reactions and pathways involving polyketides, any of a diverse group of natural products synthesized via linear poly-beta-ketones, which are themselves formed by repetitive head-to-tail addition of acetyl (or substituted acetyl) units indirectly derived from acetate (or a substituted acetate) by a mechanism similar to that for fatty acid biosynthesis but without the intermediate reductive steps.
30639	polyketide biosynthetic process	P	The chemical reactions and pathways resulting in the formation of polyketides, any of a diverse group of natural products synthesized via linear poly-beta-ketones, which are themselves formed by repetitive head-to-tail addition of acetyl (or substituted acetyl) units indirectly derived from acetate (or a substituted acetate) by a mechanism similar to that for fatty acid biosynthesis but without the intermediate reductive steps.
30640	polyketide catabolic process	P	The chemical reactions and pathways resulting in the breakdown of polyketides, any of a diverse group of natural products synthesized via linear poly-beta-ketones, which are themselves formed by repetitive head-to-tail addition of acetyl (or substituted acetyl) units indirectly derived from acetate (or a substituted acetate) by a mechanism similar to that for fatty acid biosynthesis but without the intermediate reductive steps.
30641	regulation of cellular pH	P	Any process involved in the maintenance of an internal equilibrium of hydrogen ions (protons) within a cell or between a cell and its external environment.
30642	cellular sulfate ion homeostasis	P	Any process involved in the maintenance of an internal steady state of sulfate ions at the level of a cell.
30643	cellular phosphate ion homeostasis	P	Any process involved in the maintenance of an internal steady state of phosphate ions at the level of a cell.
30644	cellular chloride ion homeostasis	P	Any process involved in the maintenance of an internal steady state of chloride ions at the level of a cell.
30645	glucose catabolic process to butyrate	P	The anaerobic chemical reactions and pathways resulting in the breakdown of glucose, with the production of acetic acid, butyric acid, carbon dioxide (CO2), and dihydrogen; effected by some saccharolytic species of Clostridium, e.g. C. butyricum.
30647	aminoglycoside antibiotic metabolic process	P	The chemical reactions and pathways involving an aminoglycoside antibiotic, any member of a group of broad spectrum antibiotics, of similar toxicity and pharmacology, that contain an aminodeoxysugar, an amino- or guanidino-substituted inositol ring, and one or more residues of other sugars. The group includes streptomycin, neomycin, framycetin, kanamycin, paromomycin, and gentamicin.
30648	aminoglycoside antibiotic biosynthetic process	P	The chemical reactions and pathways resulting in the formation of an aminoglycoside antibiotic, any member of a group of broad spectrum antibiotics, of similar toxicity and pharmacology, that contain an aminodeoxysugar, an amino- or guanidino-substituted inositol ring, and one or more residues of other sugars. The group includes streptomycin, neomycin, framycetin, kanamycin, paromomycin, and gentamicin.
30649	aminoglycoside antibiotic catabolic process	P	The chemical reactions and pathways resulting in the breakdown of an aminoglycoside antibiotic, any member of a group of broad spectrum antibiotics, of similar toxicity and pharmacology, that contain an aminodeoxysugar, an amino- or guanidino-substituted inositol ring, and one or more residues of other sugars. The group includes streptomycin, neomycin, framycetin, kanamycin, paromomycin, and gentamicin.
30650	peptide antibiotic metabolic process	P	The chemical reactions and pathways involving peptides with antibiotic activity.
30651	peptide antibiotic biosynthetic process	P	The chemical reactions and pathways resulting in the formation of peptides with antibiotic activity.
30652	peptide antibiotic catabolic process	P	The chemical reactions and pathways resulting in the breakdown of peptides with antibiotic activity.
30653	beta-lactam antibiotic metabolic process	P	The chemical reactions and pathways involving a beta-lactam antibiotic, any member of a class of natural or semisynthetic antibiotics whose characteristic feature is a strained, four-membered beta-lactam ring. They include the penicillins and many of the cephalosporins.
30654	beta-lactam antibiotic biosynthetic process	P	The chemical reactions and pathways resulting in the formation of a beta-lactam antibiotic, any member of a class of natural or semisynthetic antibiotics whose characteristic feature is a strained, four-membered beta-lactam ring. They include the penicillins and many of the cephalosporins.
30655	beta-lactam antibiotic catabolic process	P	The chemical reactions and pathways resulting in the breakdown of a beta-lactam antibiotic, any member of a class of natural or semisynthetic antibiotics whose characteristic feature is a strained, four-membered beta-lactam ring. They include the penicillins and many of the cephalosporins.
30656	regulation of vitamin metabolic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a vitamin, one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body.
30658	transport vesicle membrane	C	The lipid bilayer surrounding a transport vesicle.
30659	cytoplasmic vesicle membrane	C	The lipid bilayer surrounding a cytoplasmic vesicle.
30660	Golgi-associated vesicle membrane	C	The lipid bilayer surrounding a vesicle associated with the Golgi apparatus.
30661	chitosome membrane	C	The lipid bilayer surrounding a chitosome.
30662	coated vesicle membrane	C	The lipid bilayer surrounding a coated vesicle.
30663	COPI-coated vesicle membrane	C	The lipid bilayer surrounding a COPI-coated vesicle.
30665	clathrin-coated vesicle membrane	C	The lipid bilayer surrounding a clathrin-coated vesicle.
30666	endocytic vesicle membrane	C	The lipid bilayer surrounding an endocytic vesicle.
30667	secretory granule membrane	C	The lipid bilayer surrounding a secretory granule.
30668	merozoite dense granule membrane	C	The lipid bilayer surrounding a dense granule of the type found in apicomplexan parasites.
30669	clathrin-coated endocytic vesicle membrane	C	The lipid bilayer surrounding a clathrin-coated endocytic vesicle.
30670	phagocytic vesicle membrane	C	The lipid bilayer surrounding a phagocytic vesicle.
30671	clathrin-coated phagocytic vesicle membrane	C	The lipid bilayer surrounding a clathrin-coated phagocytic vesicle.
30672	synaptic vesicle membrane	C	The lipid bilayer surrounding a synaptic vesicle.
30673	axolemma	C	The portion of the plasma membrane surrounding an axon; it is a specialized trilaminar random mosaic of protein molecules floating within a fluid matrix of highly mobile phospholipid molecules, 7-8 nm in thickness.
30674	protein binding, bridging	F	The binding activity of a molecule that brings together two or more protein molecules, or a protein and another macromolecule or complex, through a selective, non-covalent, often stoichiometric interaction, permitting those molecules to function in a coordinated way.
30676	Rac guanyl-nucleotide exchange factor activity	F	Stimulates the exchange of guanyl nucleotides associated with a GTPase of the Rac family. Under normal cellular physiological conditions, the concentration of GTP is higher than that of GDP, favoring the replacement of GDP by GTP in association with the GTPase.
30677	ribonuclease P complex	C	A ribonucleoprotein complex that catalyzes cleavage of the leader sequence of precursor tRNAs (pre-tRNAs), generating the mature 5' end of tRNAs.
30678	mitochondrial ribonuclease P complex	C	A ribonuclease P complex located in the mitochondrion of a eukaryotic cell, where it catalyzes the 5' endonucleolytic cleavage of precursor tRNAs to yield mature tRNAs. The subunit composition of mitochondrial ribonuclease P complexes varies between species, but the complex often contains a single RNA molecule and a single protein molecule.
30679	cyanelle ribonuclease P complex	C	A ribonuclease P complex located in the cyanelle, where it catalyzes the 5' endonucleolytic cleavage of precursor tRNAs to yield mature tRNAs. The best characterized cyanelle ribonuclease P complex, from the alga Cyanophora paradoxa, contains a single RNA molecule that is necessary but not sufficient for catalysis, and several protein molecules.
30680	dimeric ribonuclease P complex	C	A ribonuclease P complex that contains a single RNA molecule that is necessary and usually sufficient for catalysis, and a single protein molecule. Examples of this complex are found in Bacterial species.
30681	multimeric ribonuclease P complex	C	A ribonuclease P complex that generally contains a single RNA molecule and several protein molecules. Examples of this complex are found in Archaeal species.
30682	evasion or tolerance of host defense response	P	Any process, either active or passive, by which an organism avoids or tolerates the effects of its host organism's defense response. The host defense response is mounted by the host in response to the presence of the organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
30683	evasion or tolerance by virus of host immune response	P	Any process, either active or passive, by which a virus avoids the effects of the host organism's immune response. The host is defined as the larger of the organisms involved in a symbiotic interaction.
30684	preribosome	C	Any complex of pre-rRNAs, ribosomal proteins, and associated proteins formed during ribosome biogenesis.
30685	nucleolar preribosome	C	Any complex of pre-rRNAs, ribosomal proteins, and associated proteins formed in the nucleolus during ribosome biogenesis.
30686	90S preribosome	C	A large ribonucleoprotein complex considered to be the earliest preribosomal complex. In S. cerevisiae, it has a size of 90S and consists of the 35S pre-rRNA, early-associating ribosomal proteins most of which are part of the small ribosomal subunit, the U3 snoRNA and associated proteins.
30687	preribosome, large subunit precursor	C	A preribosomal complex consisting of 27SA, 27SB, and/or 7S pre-rRNA, 5S rRNA, ribosomal proteins including late-associating large subunit proteins, and associated proteins; a precursor of the eukaryotic cytoplasmic large ribosomal subunit.
30688	preribosome, small subunit precursor	C	A preribosomal complex consisting of 20S pre-rRNA, ribosomal proteins including late-associating small subunit proteins, and associated proteins; a precursor of the eukaryotic cytoplasmic small ribosomal subunit.
30689	Noc complex	C	Any of several heterodimers containing one or two Noc proteins, associated with preribosomal complexes; involved in ribosome biogenesis.
30690	Noc1p-Noc2p complex	C	A heterodimer associated with 90S and 66S preribosomes. Predominantly, but not exclusively, nucleolar; involved in ribosomal large subunit biogenesis.
30691	Noc2p-Noc3p complex	C	A heterodimer associated with 66S preribosomes; predominantly nucleoplasmic, but also locates to the nucleolus; involved in ribosomal large subunit biogenesis.
30692	Noc4p-Nop14p complex	C	A heterodimer associated with precursors of the eukaryotic small ribosomal subunit, including the 90S preribosome; involved in small subunit biogenesis.
30694	bacterial-type flagellum basal body, rod	C	The central portion of the flagellar basal body, which spans the periplasm and threads through the rings. Examples of this component are found in Bacterial species.
30695	GTPase regulator activity	F	Modulates the rate of GTP hydrolysis by a GTPase.
30696	tRNA (m5U54) methyltransferase activity	F	Catalysis of the transfer of a methyl group from a donor to the C5 atom of the uridine residue at position 54 in a tRNA molecule.
30697	S-adenosylmethionine-dependent tRNA (m5U54) methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing thymine at position U54 of a transfer RNA. This occurs in most Gram-negative bacteria, some archae, and eukaryotes.
30698	5,10-methylenetetrahydrofolate-dependent tRNA (m5U54) methyltransferase activity	F	Catalysis of the transfer of a methyl group from 5,10-methylenetetrahydrofolate to the C5 atom of the uridine residue at position 54 in a tRNA molecule. This occurs in most Gram-positive bacteria and some Gram-negative bacteria.
30699	glycine reductase activity	F	Catalysis of the reaction: acetyl phosphate + H(2)O + NH(4)(+) + thioredoxin disulfide = glycine + H(+) + phosphate + thioredoxin.
30700	glycine reductase complex	C	Complex that possesses glycine reductase activity; usually comprises three subunits, of which two are selenoproteins; the subunits are typically designated selenoprotein A, selenoprotein B and protein C.
30701	NAD+-dinitrogen-reductase ADP-D-ribosyltransferase activity	F	Catalysis of the reaction: NAD+ + [dinitrogen reductase] = nicotinamide + ADP-D-ribosyl-[dinitrogen reductase].
30702	chromatin silencing at centromere	P	Repression of transcription of centromeric DNA by altering the structure of chromatin.
30703	eggshell formation	P	Construction of the eggshell, a product of the somatic follicle cell epithelium and a structure that supports the egg in a hostile environment, minimizing water loss whilst allowing gas exchanges essential for embryonic respiration.
30704	vitelline membrane formation	P	Construction of the vitelline membrane portion of the egg shell, a rigid structure required to maintain the shape of the egg.
30705	cytoskeleton-dependent intracellular transport	P	The directed movement of substances along cytoskeletal fibers such as microfilaments or microtubules within a cell.
30706	germarium-derived oocyte differentiation	P	The process in which one relatively unspecialized immature cystocyte of the germ-line cyst in the germarium acquires the specialized features of an oocyte. An example of this process can be found in Drosophila melanogaster.
30707	ovarian follicle cell development	P	The process that occurs during oogenesis involving the ovarian follicle cells, somatic cells which surround the germ cells of an ovary. An example of this is found in Drosophila melanogaster.
30708	germarium-derived female germ-line cyst encapsulation	P	Formation of a single follicular epithelium around the germ-line derived cells of a cyst formed in the germarium. An example of this process is found in Drosophila melanogaster.
30709	border follicle cell delamination	P	The delamination process that results in the splitting off of border cells from the anterior epithelium, prior to border cell migration.
30710	regulation of border follicle cell delamination	P	Any process that regulates the frequency, rate or extent of border cell delamination.
30711	positive regulation of border follicle cell delamination	P	Any process that increases the frequency, rate or extent of border cell delamination.
30712	negative regulation of border follicle cell delamination	P	Any process that decreases the frequency, rate or extent of border cell delamination.
30713	ovarian follicle cell stalk formation	P	Development of ovarian follicle cells to create the interfollicular stalks that connect the egg chambers of progressive developmental stages. An example of this process is found in Drosophila melanogaster.
30714	anterior/posterior axis specification, follicular epithelium	P	Polarization of the follicle cells of an insect ovary along the anterior/posterior axis.
30715	oocyte growth in germarium-derived egg chamber	P	The increase in volume of an oocyte during the growth phase of the egg chamber, once the egg chamber has left the germarium. An example of this process is found in Drosophila melanogaster.
30716	oocyte fate determination	P	The process in which a cell becomes capable of differentiating autonomously into an oocyte cell regardless of its environment; upon determination, the cell fate cannot be reversed.
30717	karyosome formation	P	The chromosome organization process in which meiotic chromosomes in the oocyte nucleus cluster together to form a compact spherical structure called the karyosome.
30718	germ-line stem cell population maintenance	P	Any process by which an organism or tissue maintains a population of germ-line stem cells.
30719	P granule organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of polar granules, cytoplasmic, non-membranous RNA/protein complex aggregates in the primordial germ cells of many higher eukaryotes.
30720	oocyte localization involved in germarium-derived egg chamber formation	P	Directed movement of the oocyte, following its specification, from its original central position in the cyst to a posterior position relative to the nurse cells of the egg chamber, and its maintenance in this posterior location. This is the first sign of anterior-posterior asymmetry in the developing egg chamber.
30721	spectrosome organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the spectrosome, a germline specific spherical organelle that is the precursor to the fusome.
30722	establishment of oocyte nucleus localization involved in oocyte dorsal/ventral axis specification	P	The directed movement of the nucleus to a specific location within the cell during the establishment and maintenance of the dorsal/ventral axis of the oocyte. In the insect oocyte, for example, the nucleus is repositioned to a dorso-anterior position.
30723	ovarian fusome organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the fusome of ovarian cells, an organelle derived from the spectrosome. It anchors the mitotic spindle pole to provide orientation during cystoblast cell divisions.
30724	testicular fusome organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the fusome of testicular cells, an organelle derived from the spectrosome.
30725	germline ring canal formation	P	Assembly of the cytoplasmic bridges between developing spermatogonial or oogonial cysts.
30726	male germline ring canal formation	P	Formation of the intercellular bridges that connect the germ-line cells of a male cyst.
30727	germarium-derived female germ-line cyst formation	P	Formation, in a germarium, of a group of interconnected cells derived from a single female gonial founder cell (a cystoblast). The germarium is the most anterior portion of an insect ovariole. An example of this process is found in Drosophila melanogaster.
30728	ovulation	P	The release of a mature ovum/oocyte from an ovary.
30729	acetoacetate-CoA ligase activity	F	Catalysis of the reaction: acetoacetate + ATP + CoA = acetoacetyl-CoA + AMP + diphosphate + H(+).
30730	sequestering of triglyceride	P	The process of binding or confining any triester of glycerol such that it is separated from other components of a biological system.
30731	guanidinoacetate N-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + guanidinoacetate = S-adenosyl-L-homocysteine + creatine + H(+).
30732	methionine S-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + L-methionine = S-adenosyl-L-homocysteine + S-methyl-L-methionine.
30733	fatty acid O-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + a fatty acid = S-adenosyl-L-homocysteine + a fatty acid methyl ester.
30734	polysaccharide O-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + 1,4-N1-D-glucooligosaccharide = S-adenosyl-L-homocysteine + oligosaccharide containing 6-methyl-D-glucose units.
30735	carnosine N-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + carnosine = S-adenosyl-L-homocysteine + anserine + H(+).
30736	phenol O-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + phenol = S-adenosyl-L-homocysteine + anisole + H(+).
30737	iodophenol O-methyltransferase activity	F	Catalysis of the reaction: 2-iodophenol + S-adenosyl-L-methionine = 1-iodo-2-methoxybenzene + S-adenosyl-L-homocysteine + H(+).
30738	tyramine N-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + tyramine = N-methyltyramine + S-adenosyl-L-homocysteine + H(+).
30739	O-demethylpuromycin O-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + O-demethylpuromycin = S-adenosyl-L-homocysteine + puromycin.
30740	inositol 3-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine(1+) + myo-inositol = 1D-3-O-methyl-myo-inositol + S-adenosyl-L-homocysteine + H(+).
30741	inositol 1-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine(1+) + myo-inositol = 1D-1-O-methyl-myo-inositol + S-adenosyl-L-homocysteine + H(+).
30742	GTP-dependent protein binding	F	Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules) using energy from the hydrolysis of GTP.
30743	rRNA (adenosine-2'-O-)-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing a single residue of 2'-O-methyladenosine.
30744	luteolin O-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + luteolin = 4',5,7-trihydroxy-3'-methoxyflavone + S-adenosyl-L-homocysteine + H(+).
30745	dimethylhistidine N-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + N-alpha,N-alpha-dimethyl-L-histidine = S-adenosyl-L-homocysteine + N-alpha,N-alpha,N-alpha-trimethyl-L-histidine.
30746	isoflavone 4'-O-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + isoflavone = S-adenosyl-L-homocysteine + 4'-O-methylisoflavone.
30747	indolepyruvate C-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + (indol-3-yl)pyruvate = S-adenosyl-L-homocysteine + (S)-3-(indol-3-yl)-2-oxobutanoate.
30748	amine N-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + an amine = S-adenosyl-L-homocysteine + a methylated amine.
30749	loganate O-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + loganate = S-adenosyl-L-homocysteine + loganin.
30750	putrescine N-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + putrescine = N-methylputrescine + S-adenosyl-L-homocysteine + H(+).
30751	licodione 2'-O-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine(1+) + licodione = 2'-O-methyllicodione + S-adenosyl-L-homocysteine + H(+).
30752	5-hydroxyfuranocoumarin 5-O-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + 5-hydroxyfuranocoumarin = S-adenosyl-L-homocysteine + 5-methoxyfuranocoumarin.
30753	8-hydroxyfuranocoumarin 8-O-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + xanthotoxol = S-adenosyl-L-homocysteine + xanthotoxin. Xanthotoxol is also known as 8-hydroxyfuranocoumarin and xanthotoxin as 8-methoxyfuranocoumarin.
30754	apigenin 4'-O-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + 5,7,4'-trihydroxyflavone = S-adenosyl-L-homocysteine + 4'-methoxy-5,7-dihydroxyflavone.
30755	quercetin 3-O-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + 3,5,7,3',4'-pentahydroxyflavone = S-adenosyl-L-homocysteine + 3-methoxy-5,7,3',4'-tetrahydroxy-flavone.
30756	isoorientin 3'-O-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine(1+) + isoorientin = S-adenosyl-L-homocysteine + H(+) + isoscoparin.
30757	3-methylquercitin 7-O-methyltransferase activity	F	Catalysis of the reaction: 3',4',5,7-tetrahydroxy-3-methoxyflavone + S-adenosyl-L-methionine(1+) = 3',4',5-trihydroxy-3,7-dimethoxyflavone + S-adenosyl-L-homocysteine.
30758	3,7-dimethylquercitin 4'-O-methyltransferase activity	F	Catalysis of the reaction: 3',4',5-trihydroxy-3,7-dimethoxyflavone + S-adenosyl-L-methionine(1+) = 3',5-dihydroxy-3,4',7-trimethoxyflavone + S-adenosyl-L-homocysteine + H(+).
30759	methylquercetagetin 6-O-methyltransferase activity	F	Catalysis of the reaction: 3',4',5,6-tetrahydroxy-3,7-dimethoxyflavone + S-adenosyl-L-methionine(1+) = 3',4',5-trihydroxy-3,6,7-trimethoxyflavone + S-adenosyl-L-homocysteine + H(+).
30760	pyridine N-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine(1+) + pyridine = N-methylpyridinium + S-adenosyl-L-homocysteine.
30761	8-hydroxyquercitin 8-O-methyltransferase activity	F	Catalysis of the reaction: 3,3',4',5,7,8-hexahydroxyflavone + S-adenosyl-L-methionine(1+) = 3,3',4',5,7-pentahydroxy-8-methoxyflavone + S-adenosyl-L-homocysteine + H(+).
30762	tetrahydrocolumbamine 2-O-methyltransferase activity	F	Catalysis of the reaction: (S)-tetrahydrocolumbamine + S-adenosyl-L-methionine(1+) = S-adenosyl-L-homocysteine + H(+) + tetrahydropalmatine.
30763	isobutyraldoxime O-methyltransferase activity	F	Catalysis of the reaction: 2-methylpropanal oxime + S-adenosyl-L-methionine = 2-methylpropanal O-methyloxime + S-adenosyl-L-homocysteine + H(+).
30766	11-O-demethyl-17-O-deacetylvindoline O-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + 11-O-demethyl-17-O-deacetylvindoline = S-adenosyl-L-homocysteine + 17-O-deacetylvindoline.
30767	3-hydroxyanthranilate 4-C-methyltransferase activity	F	Catalysis of the reaction: 3-hydroxyanthranilate + S-adenosyl-L-methionine = 3-hydroxy-4-methylanthranilate + S-adenosyl-L-homocysteine + H(+).
30768	16-methoxy-2,3-dihydro-3-hydroxytabersonine N-methyltransferase activity	F	Catalysis of the reaction: (3R)-3-hydroxy-16-methoxy-2,3-dihydrotabersonine + S-adenosyl-L-methionine = S-adenosyl-L-homocysteine + deacetoxyvindoline + H(+).
30769	macrocin O-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine(1+) + macrocin = S-adenosyl-L-homocysteine + H(+) + tylosin.
30770	demethylmacrocin O-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine(1+) + demethylmacrocin = S-adenosyl-L-homocysteine + H(+) + macrocin.
30771	N-benzoyl-4-hydroxyanthranilate 4-O-methyltransferase activity	F	Catalysis of the reaction: N-benzoyl-4-hydroxyanthranilate + S-adenosyl-L-methionine(1+) = N-benzoyl-4-methoxyanthranilate + S-adenosyl-L-homocysteine + H(+).
30772	tryptophan 2-C-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine(1+) + L-tryptophan = S-adenosyl-L-homocysteine + L-2-methyltryptophan + H(+).
30773	6-hydroxymellein O-methyltransferase activity	F	Catalysis of the reaction: 6-hydroxymellein + S-adenosyl-L-methionine = 6-methoxymellein + S-adenosyl-L-homocysteine + H(+).
30774	anthranilate N-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + anthranilate = N-methylanthranilate + S-adenosyl-L-homocysteine + H(+).
30775	glucuronoxylan 4-O-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + glucuronoxylan D-glucuronate = S-adenosyl-L-homocysteine + glucuronoxylan 4-O-methyl-D-glucuronate.
30776	(RS)-1-benzyl-1,2,3,4-tetrahydroisoquinoline N-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + (RS)-1-benzyl-1,2,3,4-tetrahydroisoquinoline = S-adenosyl-L-homocysteine + N-methyl-(RS)-1-benzyl-1,2,3,4-tetrahydroisoquinoline.
30777	(S)-scoulerine 9-O-methyltransferase activity	F	Catalysis of the reaction: (S)-scoulerine + S-adenosyl-L-methionine(1+) = (S)-tetrahydrocolumbamine + S-adenosyl-L-homocysteine + H(+).
30778	columbamine O-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + columbamine = S-adenosyl-L-homocysteine + H(+) + palmatine.
30779	10-hydroxydihydrosanguinarine 10-O-methyltransferase activity	F	Catalysis of the reaction: 10-hydroxydihydrosanguinarine + S-adenosyl-L-methionine(1+) = S-adenosyl-L-homocysteine + dihydrochelirubine + H(+).
30780	12-hydroxydihydrochelirubine 12-O-methyltransferase activity	F	Catalysis of the reaction: 12-hydroxydihydrochelirubine + S-adenosyl-L-methionine(1+) = S-adenosyl-L-homocysteine + dihydromacarpine + H(+).
30781	6-O-methylnorlaudanosoline 5'-O-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + 6-O-methylnorlaudanosoline = S-adenosyl-L-homocysteine + nororientaline.
30782	(S)-tetrahydroprotoberberine N-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + (S)-7,8,13,14-tetrahydroprotoberberine = S-adenosyl-L-homocysteine + cis-N-methyl-(S)-7,8,13,14-tetrahydroprotoberberine.
30783	[cytochrome c]-methionine S-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + [cytochrome c]-methionine = S-adenosyl-L-homocysteine + [cytochrome c]-S-methyl-methionine.
30784	3'-hydroxy-N-methyl-(S)-coclaurine 4'-O-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + 3'-hydroxy-N-methyl-(S)-coclaurine = S-adenosyl-L-homocysteine + (S)-reticuline.
30785	[ribulose-bisphosphate carboxylase]-lysine N-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + [ribulose-1,5-bisphosphate carboxylase]-lysine = S-adenosyl-L-homocysteine + [ribulose-1,5-bisphosphate carboxylase]-N6-methyl-L-lysine.
30786	(RS)-norcoclaurine 6-O-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + (RS)-norcoclaurine = S-adenosyl-L-homocysteine + (RS)-coclaurine.
30787	inositol 4-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine(1+) + myo-inositol = 1D-4-O-methyl-myo-inositol + S-adenosyl-L-homocysteine + H(+).
30788	precorrin-2 C20-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + precorrin-2 = S-adenosyl-L-homocysteine + H(+) + precorrin-3A.
30789	precorrin-3B C17-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + precorrin-3B = S-adenosyl-L-homocysteine + precorrin 4.
30790	chlorophenol O-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + trichlorophenol = S-adenosyl-L-homocysteine + trichloroanisole.
30791	arsenite methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + arsenite = S-adenosyl-L-homocysteine + methylarsonate.
30792	methylarsonite methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + methylarsonite = S-adenosyl-L-homocysteine + dimethylarsinate.
30793	3'-demethylstaurosporine O-methyltransferase activity	F	Catalysis of the reaction: 3'-demethylstaurosporine + S-adenosyl-L-methionine = S-adenosyl-L-homocysteine + H(+) + staurosporine.
30794	(S)-coclaurine-N-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + (S)-coclaurine = S-adenosyl-L-homocysteine + (S)-N-methylcoclaurine.
30795	jasmonate O-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + jasmonate = S-adenosyl-L-homocysteine + methyljasmonate.
30796	cycloartenol 24-C-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + cycloartenol = (24R)-24-methylcycloart-25-en-3beta-ol + S-adenosyl-L-homocysteine + H(+).
30797	24-methylenesterol C-methyltransferase activity	F	Catalysis of the reaction: 24-methylidenelophenol + S-adenosyl-L-methionine(1+) = (Z)-24-ethylidenelophenol + S-adenosyl-L-homocysteine + H(+).
30798	trans-aconitate 2-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + trans-aconitate = (E)-3-(methoxycarbonyl)pent-2-enedioate + S-adenosyl-L-homocysteine.
30799	regulation of cyclic nucleotide metabolic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving cyclic nucleotides.
30800	negative regulation of cyclic nucleotide metabolic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving cyclic nucleotides.
30801	positive regulation of cyclic nucleotide metabolic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving cyclic nucleotides.
30802	regulation of cyclic nucleotide biosynthetic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cyclic nucleotides.
30803	negative regulation of cyclic nucleotide biosynthetic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cyclic nucleotides.
30804	positive regulation of cyclic nucleotide biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cyclic nucleotides.
30805	regulation of cyclic nucleotide catabolic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of cyclic nucleotides.
30806	negative regulation of cyclic nucleotide catabolic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of chemical reactions and pathways resulting in the breakdown of cyclic nucleotides.
30807	positive regulation of cyclic nucleotide catabolic process	P	Any process that activates or increases the frequency, rate or extent of chemical reactions and pathways resulting in the breakdown of cyclic nucleotides.
30808	regulation of nucleotide biosynthetic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of nucleotides.
30809	negative regulation of nucleotide biosynthetic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of nucleotides.
30810	positive regulation of nucleotide biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of nucleotides.
30811	regulation of nucleotide catabolic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of nucleotides.
30812	negative regulation of nucleotide catabolic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of nucleotides.
30813	positive regulation of nucleotide catabolic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of nucleotides.
30814	regulation of cAMP metabolic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving the nucleotide cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate).
30815	negative regulation of cAMP metabolic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving the nucleotide cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate).
30816	positive regulation of cAMP metabolic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving the nucleotide cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate).
30817	regulation of cAMP biosynthetic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of the nucleotide cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate).
30818	negative regulation of cAMP biosynthetic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of the nucleotide cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate).
30819	positive regulation of cAMP biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of the nucleotide cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate).
30820	regulation of cAMP catabolic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of the nucleotide cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate).
30821	negative regulation of cAMP catabolic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of the nucleotide cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate).
30822	positive regulation of cAMP catabolic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of the nucleotide cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate).
30823	regulation of cGMP metabolic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving cGMP.
30824	negative regulation of cGMP metabolic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving cGMP.
30825	positive regulation of cGMP metabolic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving cGMP.
30826	regulation of cGMP biosynthetic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cGMP.
30827	negative regulation of cGMP biosynthetic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cGMP.
30828	positive regulation of cGMP biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cGMP.
30829	regulation of cGMP catabolic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of cGMP.
30830	negative regulation of cGMP catabolic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of cGMP.
30831	positive regulation of cGMP catabolic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of cGMP.
30832	regulation of actin filament length	P	Any process that controls the length of actin filaments in a cell.
30833	regulation of actin filament polymerization	P	Any process that modulates the frequency, rate or extent of the assembly of actin filaments by the addition of actin monomers to a filament.
30834	regulation of actin filament depolymerization	P	Any process that modulates the frequency, rate or extent of the disassembly of actin filaments by the removal of actin monomers from a filament.
30835	negative regulation of actin filament depolymerization	P	Any process that stops, prevents, or reduces the frequency, rate or extent of actin depolymerization.
30836	positive regulation of actin filament depolymerization	P	Any process that activates or increases the frequency, rate or extent of actin depolymerization.
30837	negative regulation of actin filament polymerization	P	Any process that stops, prevents, or reduces the frequency, rate or extent of actin polymerization.
30838	positive regulation of actin filament polymerization	P	Any process that activates or increases the frequency, rate or extent of actin polymerization.
30839	regulation of intermediate filament polymerization	P	Any process that modulates the frequency, rate or extent of the assembly of intermediate filaments by the addition of monomers to a filament.
30840	negative regulation of intermediate filament polymerization	P	Any process that stops, prevents, or reduces the frequency, rate or extent of intermediate filament polymerization.
30841	positive regulation of intermediate filament polymerization	P	Any process that activates or increases the frequency, rate or extent of intermediate filament polymerization.
30842	regulation of intermediate filament depolymerization	P	Any process that modulates the frequency, rate or extent of the disassembly of intermediate filaments by the removal of monomers from a filament.
30843	negative regulation of intermediate filament depolymerization	P	Any process that stops, prevents, or reduces the frequency, rate or extent of intermediate filament depolymerization.
30844	positive regulation of intermediate filament depolymerization	P	Any process that activates or increases the frequency, rate or extent of intermediate filament depolymerization.
30845	phospholipase C-inhibiting G-protein coupled receptor signaling pathway	P	A G-protein coupled receptor signaling pathway which proceeds with inhibition of phospholipase C (PLC) activity and a subsequent decrease in the levels of cellular inositol trisphosphate (IP3) and diacylglycerol (DAG).
30846	termination of RNA polymerase II transcription, poly(A)-coupled	P	The process in which transcription of polyadenylated RNA polymerase II transcripts is terminated; cleavage and polyadenylylation of the mRNA 3' end is coupled to transcription termination.
30847	termination of RNA polymerase II transcription, exosome-dependent	P	The process in which transcription of nonpolyadenylated RNA polymerase II transcripts is terminated; coupled to the maturation of the RNA 3'-end.
30848	threo-3-hydroxyaspartate ammonia-lyase activity	F	Catalysis of the reaction: (3S)-3-hydroxy-L-aspartate = NH(4)(+) + oxaloacetate.
30849	autosome	C	Any chromosome other than a sex chromosome.
30850	prostate gland development	P	The process whose specific outcome is the progression of the prostate gland over time, from its formation to the mature structure. The prostate gland is a partly muscular, partly glandular body that is situated near the base of the mammalian male urethra and secretes an alkaline viscid fluid which is a major constituent of the ejaculatory fluid.
30851	granulocyte differentiation	P	The process in which a myeloid precursor cell acquires the specialized features of a granulocyte. Granulocytes are a class of leukocytes characterized by the presence of granules in their cytoplasm. These cells are active in allergic immune reactions such as arthritic inflammation and rashes. This class includes basophils, eosinophils and neutrophils.
30852	regulation of granulocyte differentiation	P	Any process that modulates the frequency, rate or extent of granulocyte differentiation.
30853	negative regulation of granulocyte differentiation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of granulocyte differentiation.
30854	positive regulation of granulocyte differentiation	P	Any process that activates or increases the frequency, rate or extent of granulocyte differentiation.
30855	epithelial cell differentiation	P	The process in which a relatively unspecialized cell acquires specialized features of an epithelial cell, any of the cells making up an epithelium.
30856	regulation of epithelial cell differentiation	P	Any process that modulates the frequency, rate or extent of epithelial cell differentiation.
30857	negative regulation of epithelial cell differentiation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of epithelial cell differentiation.
30858	positive regulation of epithelial cell differentiation	P	Any process that activates or increases the frequency, rate or extent of epithelial cell differentiation.
30859	polarized epithelial cell differentiation	P	The process in which a relatively unspecialized cell acquires specialized features of a polarized epithelial cell. The polarized epithelial cell can be any of the cells within an epithelium where the epithelial sheet is oriented with respect to the planar axis.
30860	regulation of polarized epithelial cell differentiation	P	Any process that modulates the frequency, rate or extent of polarized epithelial cell differentiation.
30861	negative regulation of polarized epithelial cell differentiation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of polarized epithelial cell differentiation.
30862	positive regulation of polarized epithelial cell differentiation	P	Any process that activates or increases the rate or extent of polarized epithelial cell differentiation.
30863	cortical cytoskeleton	C	The portion of the cytoskeleton that lies just beneath the plasma membrane.
30864	cortical actin cytoskeleton	C	The portion of the actin cytoskeleton, comprising filamentous actin and associated proteins, that lies just beneath the plasma membrane.
30865	cortical cytoskeleton organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures in the cell cortex, i.e. just beneath the plasma membrane.
30866	cortical actin cytoskeleton organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of actin-based cytoskeletal structures in the cell cortex, i.e. just beneath the plasma membrane.
30867	rough endoplasmic reticulum membrane	C	The lipid bilayer surrounding the rough endoplasmic reticulum.
30868	smooth endoplasmic reticulum membrane	C	The lipid bilayer surrounding the smooth endoplasmic reticulum.
30869	RENT complex	C	A protein complex that mediates transcriptional silencing at the rDNA locus (the name derives from regulator of nucleolar silencing and telophase). In Saccharomyces the complex contains Net1p, Sir2p, Cdc14p, and at least one more subunit.
30870	Mre11 complex	C	Trimeric protein complex that possesses endonuclease activity; involved in meiotic recombination, DNA repair and checkpoint signaling. In Saccharomyces cerevisiae, the complex comprises Mre11p, Rad50p, and Xrs2p; complexes identified in other species generally contain proteins orthologous to the Saccharomyces cerevisiae proteins.
30874	nucleolar chromatin	C	The portion of nuclear chromatin associated with the nucleolus; includes the DNA encoding the ribosomal RNA.
30875	rDNA protrusion	C	Any of the tandem arrays of rDNA localized at the periphery of the nucleus and protruding into the nucleolus, and associated proteins. May be visible as a single or double spot by DAPI staining.
30876	interleukin-20 receptor complex	C	A protein complex composed of an alpha and a beta receptor subunit and an interleukin ligand. In human, Interleukin-19, -20 and -24 bind IL20RA/IL20RB receptor subunits and Interleukin-20 and -24 bind IL22RA1/IL20RB receptor subunits.
30877	beta-catenin destruction complex	C	A cytoplasmic protein complex containing glycogen synthase kinase-3-beta (GSK-3-beta), the adenomatous polyposis coli protein (APC), and the scaffolding protein axin, among others; phosphorylates beta-catenin, targets it for degradation by the proteasome.
30878	thyroid gland development	P	The process whose specific outcome is the progression of the thyroid gland over time, from its formation to the mature structure. The thyroid gland is an endoderm-derived gland that produces thyroid hormone.
30879	mammary gland development	P	The process whose specific outcome is the progression of the mammary gland over time, from its formation to the mature structure. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk. Its development starts with the formation of the mammary line and ends as the mature gland cycles between nursing and weaning stages.
30880	RNA polymerase complex	C	Any complex that possesses RNA polymerase activity; generally comprises a catalytic subunit and one or more additional subunits.
30881	beta-2-microglobulin binding	F	Interacting selectively and non-covalently with beta-2-microglobulin.
30882	lipid antigen binding	F	Interacting selectively and non-covalently with a lipid antigen.
30883	endogenous lipid antigen binding	F	Interacting selectively and non-covalently with an endogenous cellular lipid antigen.
30884	exogenous lipid antigen binding	F	Interacting selectively and non-covalently with an exogenous lipid antigen (examples include microbial lipids and glycolipids).
30885	regulation of myeloid dendritic cell activation	P	Any process that modulates the frequency or rate of myeloid dendritic cell activation.
30886	negative regulation of myeloid dendritic cell activation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of myeloid dendritic cell activation.
30887	positive regulation of myeloid dendritic cell activation	P	Any process that stimulates, induces or increases the rate of myeloid dendritic cell activation.
30888	regulation of B cell proliferation	P	Any process that modulates the frequency, rate or extent of B cell proliferation.
30889	negative regulation of B cell proliferation	P	Any process that stops, prevents or reduces the rate or extent of B cell proliferation.
30890	positive regulation of B cell proliferation	P	Any process that activates or increases the rate or extent of B cell proliferation.
30891	VCB complex	C	A protein complex that possesses ubiquitin ligase activity; the complex is usually pentameric; for example, in mammals the subunits are pVHL, elongin B, elongin C, cullin-2 (Cul2), and Rbx1.
30892	mitotic cohesin complex	C	A cohesin complex that mediates sister chromatid cohesion during mitosis; has a subunit composition distinct from that of the meiotic cohesin complex.
30893	meiotic cohesin complex	C	A cohesin complex that mediates sister chromatid cohesion during meiosis; has a subunit composition distinct from that of the mitotic cohesin complex.
30894	replisome	C	A multi-component enzymatic machine at the replication fork which mediates DNA replication. Includes DNA primase, one or more DNA polymerases, DNA helicases, and other proteins.
30895	apolipoprotein B mRNA editing enzyme complex	C	Protein complex that mediates editing of the mRNA encoding apolipoprotein B; catalyzes the deamination of C to U (residue 6666 in the human mRNA). Contains a catalytic subunit, APOBEC-1, and other proteins (e.g. human ASP; rat ASP and KSRP).
30896	checkpoint clamp complex	C	Conserved heterotrimeric complex of PCNA-like proteins that is loaded onto DNA at sites of DNA damage.
30897	HOPS complex	C	A multimeric protein complex that associates with the vacuolar membrane, late endosomal (multivesicular body) and lysosomal membranes. HOPS is a tethering complex involved in vesicle fusion.
30898	actin-dependent ATPase activity	F	Catalysis of the reaction: ATP + H2O = ADP + phosphate. This reaction requires the presence of an actin filament to accelerate release of ADP and phosphate.
30899	calcium-dependent ATPase activity	F	Catalysis of the reaction: ATP + H2O = ADP + phosphate. This reaction requires the presence of calcium ion (Ca2+).
30900	forebrain development	P	The process whose specific outcome is the progression of the forebrain over time, from its formation to the mature structure. The forebrain is the anterior of the three primary divisions of the developing chordate brain or the corresponding part of the adult brain (in vertebrates, includes especially the cerebral hemispheres, the thalamus, and the hypothalamus and especially in higher vertebrates is the main control center for sensory and associative information processing, visceral functions, and voluntary motor functions).
30901	midbrain development	P	The process whose specific outcome is the progression of the midbrain over time, from its formation to the mature structure. The midbrain is the middle division of the three primary divisions of the developing chordate brain or the corresponding part of the adult brain (in vertebrates, includes a ventral part containing the cerebral peduncles and a dorsal tectum containing the corpora quadrigemina and that surrounds the aqueduct of Sylvius connecting the third and fourth ventricles).
30902	hindbrain development	P	The process whose specific outcome is the progression of the hindbrain over time, from its formation to the mature structure. The hindbrain is the posterior of the three primary divisions of the developing chordate brain, or the corresponding part of the adult brain (in vertebrates, includes the cerebellum, pons, and medulla oblongata and controls the autonomic functions and equilibrium).
30903	notochord development	P	The process whose specific outcome is the progression of the notochord over time, from its formation to the mature structure. The notochord is a mesoderm-derived structure located ventral of the developing nerve cord. In vertebrates, the notochord serves as a core around which other mesodermal cells form the vertebrae. In the most primitive chordates, which lack vertebrae, the notochord persists as a substitute for a vertebral column.
30904	retromer complex	C	A conserved hetero-pentameric membrane-associated complex involved in retrograde transport from endosomes to the Golgi apparatus. The budding yeast retromer comprises Vps35p, Vps29p, Vps26p, Vps5p, and Vps17p. The mammalian complex shows slight variation in composition compared to yeast, and comprises SNX1 or SNX2, SNX5 or SNX6, VPS26A or VPS26B, VPS29, and VPS35.
30905	retromer, tubulation complex	C	The dimeric subcomplex of the retromer, believed to be peripherally associated with the membrane. This dimeric complex is responsible for remodelling endosomal membranes to form a tube-structure to which cargo molecules are selected for recycling. The budding yeast complex comprises Vps5p and Vps17p, and may contain multiple copies of a Vps5p/Vps17p dimer. The mammalian complex contains SNX1 or SNX2 dimerized with SNX5 or SNX6.
30906	retromer, cargo-selective complex	C	The trimeric subcomplex of the retromer, believed to be closely associated with the membrane. This trimeric complex is responsible for recognizing and binding to cargo molecules. The complex comprises three Vps proteins in both yeast and mammalian cells: Vps35p, Vps29p, and Vps26p in yeast, and VPS35, VPS29 and VPS26A or VPS26B in mammals.
30907	MBF transcription complex	C	A protein complex that binds to the Mlu1 cell cycle box (MCB) promoter element, consensus sequence ACGCGN, and is involved in regulation of transcription during the G1/S transition of the cell cycle. In Saccharomyces, the complex contains a heterodimer of the DNA binding protein Mbp1p and the activator Swi4p, and is associated with additional proteins known as Nrm1p, Msa1p, and Msa2p; in Schizosaccharomyces the complex contains Res1p, Res2p, and Cdc10p.
30908	protein splicing	P	The post-translational removal of peptide sequences from within a protein sequence.
30909	non-intein-mediated protein splicing	P	The post-translational removal of peptide sequences from within a protein sequence, by a process not involving inteins.
30910	olfactory placode formation	P	The formation of a thickening of the neural ectoderm in the head region of the vertebrate embryo which develops into the olfactory region of the nasal cavity.
30911	TPR domain binding	F	Interacting selectively and non-covalently with a tetratricopeptide repeat (TPR) domain of a protein, the consensus sequence of which is defined by a pattern of small and large hydrophobic amino acids and a structure composed of helices.
30912	response to deep water	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a deep water stimulus, being immersed in standing deep water throughout the life cycle.
30913	paranodal junction assembly	P	Formation of the junction between an axon and the glial cell that forms the myelin sheath. Paranodal junctions form at each paranode, i.e. at the ends of the unmyelinated nodes of Ranvier.
30914	STAGA complex	C	A large multiprotein complex that possesses histone acetyltransferase and is involved in regulation of transcription. The composition is similar to that of the SAGA complex; for example, the human complex contains the transcription-transformation cofactor TRRAP, hGCN5L acetylase, novel human ADA-like and SPT-like cofactors, and a subset of TAFs.
30915	Smc5-Smc6 complex	C	A conserved complex that contains a heterodimer of SMC proteins (Smc5p and Smc6p, or homologs thereof) and several other proteins, and is involved in DNA repair and maintaining cell cycle arrest following DNA damage. In S. cerevisiae, this is an octameric complex called Mms21-Smc5-Smc6 complex, with at least five of its subunits conserved in fission yeast and humans.
30916	otic vesicle formation	P	The process resulting in the transition of the otic placode into the otic vesicle, a transient embryonic structure formed during development of the vertebrate inner ear.
30917	midbrain-hindbrain boundary development	P	The process whose specific outcome is the progression of the midbrain-hindbrain boundary over time, from its formation to the mature structure. The midbrain-hindbrain domain of the embryonic brain is comprised of the mesencephalic vesicle and the first rhombencephalic vesicle at early somitogenesis stages.
30919	peptidyl-serine O-acetylation	P	The acetylation of peptidyl-serine to form peptidyl-O-acetyl-L-serine.
30920	peptidyl-serine acetylation	P	The acetylation of peptidyl-serine.
30921	peptidyl-tyrosine dehydrogenation to form (Z)-2,3-didehydrotyrosine	P	The oxidation of the C alpha-C beta bond of peptidyl-tyrosine to form peptidyl-(Z)-2,3-didehydrotyrosine coupled with cyclization of neighboring residues.
30922	peptidyl-tyrosine dehydrogenation to form (E)-2,3-didehydrotyrosine	P	The oxidation of the C alpha-C beta bond of peptidyl-tyrosine to form peptidyl-(E)-2,3-didehydrotyrosine coupled with cyclization of neighboring residues.
30923	metal incorporation into metallo-oxygen cluster	P	The formation of a cluster of several metal atoms, including manganese or calcium, with one or more bridging (mu-bond) oxygen atoms; amino acids residues in proteins that may ligate the metal oxygen cluster are histidine, aspartate, and glutamate.
30924	manganese incorporation into metallo-oxygen cluster	P	The incorporation of manganese into a metallo-oxygen cluster.
30925	calcium incorporation into metallo-oxygen cluster	P	The incorporation of calcium into a metallo-oxygen cluster.
30926	calcium incorporation into metallo-oxygen cluster via bis-L-aspartato tris-L-glutamato L-histidino calcium tetramanganese tetroxide	P	The incorporation of calcium into a 4Mn-Ca-4O complex by bis-L-aspartato tris-L-glutamato L-histidino calcium tetramanganese tetroxide as in the photosystem II catalytic site.
30927	manganese incorporation into metallo-oxygen cluster via bis-L-aspartato tris-L-glutamato L-histidino calcium tetramanganese tetroxide	P	The incorporation of manganese into a 4Mn-Ca-4O complex by bis-L-aspartato tris-L-glutamato L-histidino calcium tetramanganese tetroxide as in the photosystem II catalytic site.
30929	ADPG pyrophosphorylase complex	C	Complex that possesses ADPG pyrophosphorylase activity. In all organisms where it has been found, the complex is a tetramer. In bacteria, it is a homotetramer. In plants, the complex is a heterotetramer composed small and large subunits.
30930	homotetrameric ADPG pyrophosphorylase complex	C	A protein complex composed of four identical subunits that possesses ADPG pyrophosphorylase activity. Examples of this component are found in Bacterial species.
30931	heterotetrameric ADPG pyrophosphorylase complex	C	A protein complex composed of four different subunits that possesses ADPG pyrophosphorylase activity. An example of this process is found in Mus musculus.
30932	amyloplast ADPG pyrophosphorylase complex	C	An ADPG pyrophosphorylase complex found in the amyloplast.
30933	chloroplast ADPG pyrophosphorylase complex	C	An ADPG pyrophosphorylase complex found in the chloroplast.
30934	anchoring collagen complex	C	Any collagen complex which links one collagen assembly, such as a collagen fibril or sheet, to other structures.
30935	sheet-forming collagen trimer	C	sheet-forming collagen trimer
30936	transmembrane collagen trimer	C	Any collagen trimer that passes through a lipid bilayer membrane.
30937	collagen type XVII trimer	C	A collagen homotrimer of alpha1(XVII) chains; type XVII collagen triple helices span the plasma membrane and associate with hemidesmosomes and the basal lamina where they bind laminin.
30938	collagen type XVIII trimer	C	A collagen homotrimer of alpha1(XVIII) chains.
30941	chloroplast targeting sequence binding	F	Interacting selectively and non-covalently with a chloroplast targeting sequence, a specific peptide sequence that acts as a signal to localize the protein within the chloroplast.
30942	endoplasmic reticulum signal peptide binding	F	Interacting selectively and non-covalently with an endoplasmic reticulum signal peptide, a specific peptide sequence that acts as a signal to localize the protein within the endoplasmic reticulum.
30943	mitochondrion targeting sequence binding	F	Interacting selectively and non-covalently with a mitochondrion targeting sequence, a specific peptide sequence that acts as a signal to localize the protein within the mitochondrion.
30944	DDEL sequence binding	F	Interacting selectively and non-covalently with a KDEL sequence, the C terminus tetrapeptide sequence Asp-Asp-Glu-Leu found in proteins that are to be retained in the endoplasmic reticulum.
30945	protein tyrosine phosphatase activity, via thiol-phosphate intermediate	F	The catalysis of phosphate removal from a phosphotyrosine using cysteine as a nucleophile and proceed by means of a thiol-phosphate intermediate.
30946	protein tyrosine phosphatase activity, metal-dependent	F	Catalysis of the reaction: protein tyrosine phosphate + H2O = protein tyrosine + phosphate. This reaction requires metal ions.
30947	regulation of vascular endothelial growth factor receptor signaling pathway	P	Any process that modulates the frequency, rate or extent of vascular endothelial growth factor receptor signaling pathway activity.
30948	negative regulation of vascular endothelial growth factor receptor signaling pathway	P	Any process that stops, prevents, or reduces the frequency, rate or extent of vascular endothelial growth factor receptor signaling pathway activity.
30949	positive regulation of vascular endothelial growth factor receptor signaling pathway	P	Any process that activates or increases the frequency, rate or extent of vascular endothelial growth factor receptor signaling pathway activity.
30950	establishment or maintenance of actin cytoskeleton polarity	P	Any cellular process that results in the specification, formation or maintenance of polarized actin-based cytoskeletal structures.
30951	establishment or maintenance of microtubule cytoskeleton polarity	P	Any cellular process that results in the specification, formation or maintenance of polarized microtubule-based cytoskeletal structures.
30952	establishment or maintenance of cytoskeleton polarity	P	Any cellular process that results in the specification, formation or maintenance of polarized cytoskeletal structures.
30953	astral microtubule organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of astral microtubules, any of the spindle microtubules that radiate in all directions from the spindle poles.
30954	astral microtubule nucleation	P	The 'de novo' formation of an astral microtubule, in which tubulin heterodimers form metastable oligomeric aggregates, some of which go on to support formation of a complete microtubule.
30955	potassium ion binding	F	Interacting selectively and non-covalently with potassium (K+) ions.
30956	glutamyl-tRNA(Gln) amidotransferase complex	C	A protein complex that possesses glutamyl-tRNA(Gln) amidotransferase activity, and therefore creates Gln-tRNA by amidating Glu-tRNA; usually composed of 3 subunits: A, B, and C. Note that the C subunit may not be required in all organisms.
30957	Tat protein binding	F	Interacting selectively and non-covalently with Tat, a viral transactivating regulatory protein from the human immunodeficiency virus, or the equivalent protein from another virus.
30958	RITS complex	C	A protein complex required for heterochromatin assembly; contains an Argonaute homolog, a chromodomain protein, and at least one additional protein; named for RNA-induced initiation of transcriptional gene silencing.
30959	peptide cross-linking via 3'-(3'-L-tyrosinyl)-L-tyrosine	P	The modification of two peptidyl-tyrosines to form a 3'-(3'-L-tyrosinyl)-L-tyrosine protein cross-link.
30960	peptide cross-linking via 3'-(O4'-L-tyrosinyl)-L-tyrosine	P	The modification of two peptidyl-tyrosines to form a 3'-(O4'-L-tyrosinyl)-L-tyrosine protein cross-link.
30961	peptidyl-arginine hydroxylation	P	The hydroxylation of peptidyl-arginine to form peptidyl-hydroxyarginine.
30962	peptidyl-arginine dihydroxylation to peptidyl-3,4-dihydroxy-L-arginine	P	The dihydroxylation of peptidyl-arginine to form peptidyl-3,4-dihydroxy-L-arginine.
30963	peptidyl-lysine dihydroxylation to 4,5-dihydroxy-L-lysine	P	The dihydroxylation of peptidyl-lysine to peptidyl-4,5-dihydroxy-L-lysine.
30964	NADH dehydrogenase complex	C	An integral membrane complex that possesses NADH oxidoreductase activity. The complex is one of the components of the electron transport chain. It catalyzes the transfer of a pair of electrons from NADH to a quinone.
30965	plasma membrane electron transport, NADH to quinone	P	The transfer of electrons from NADH to the quinone pool that occurs during oxidative phosphorylation and results in the generation of a proton gradient, mediated by the enzyme known as NADH-quinone oxidoreductase.
30968	endoplasmic reticulum unfolded protein response	P	The series of molecular signals generated as a consequence of the presence of unfolded proteins in the endoplasmic reticulum (ER) or other ER-related stress; results in changes in the regulation of transcription and translation.
30969	mRNA splicing via endonucleolytic cleavage and ligation involved in unfolded protein response	P	The spliceosome-independent cleavage and ligation of the mRNA encoding a UFP-specific transcription factor to remove a single intron, thereby increasing both the translational efficiency of the processed mRNA and the activity of the protein it encodes.
30970	retrograde protein transport, ER to cytosol	P	The directed movement of unfolded or misfolded proteins from the endoplasmic reticulum to the cytosol through the translocon.
30971	receptor tyrosine kinase binding	F	Interacting selectively and non-covalently with a receptor that possesses protein tyrosine kinase activity.
30973	molybdate ion binding	F	Interacting selectively and non-covalently with molybdate (MoO4 2-) ions.
30974	thiamine pyrophosphate transport	P	The directed movement of thiamine pyrophosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
30975	thiamine binding	F	Interacting selectively and non-covalently with thiamine (vitamin B1), a water soluble vitamin present in fresh vegetables and meats, especially liver.
30976	thiamine pyrophosphate binding	F	Interacting selectively and non-covalently with thiamine pyrophosphate, the diphosphoric ester of thiamine. Acts as a coenzyme of several (de)carboxylases, transketolases, and alpha-oxoacid dehydrogenases.
30977	taurine binding	F	Interacting selectively and non-covalently with taurine.
30978	alpha-glucan metabolic process	P	The chemical reactions and pathways involving alpha-glucans, compounds composed of glucose residues linked by alpha-D-glucosidic bonds.
30979	alpha-glucan biosynthetic process	P	The chemical reactions and pathways resulting in the formation of alpha-glucans, compounds composed of glucose residues linked by alpha-D-glucosidic bonds.
30980	alpha-glucan catabolic process	P	The chemical reactions and pathways resulting in the breakdown of alpha-glucans.
30981	cortical microtubule cytoskeleton	C	The portion of the microtubule cytoskeleton that lies just beneath the plasma membrane.
30982	adventurous gliding motility	P	A process involved in the controlled movement of a bacterial cell powered by the rearward secretion of carbohydrate slime.
30983	mismatched DNA binding	F	Interacting selectively and non-covalently with double-stranded DNA containing one or more mismatches.
30984	kininogen binding	F	Interacting selectively and non-covalently with a kininogen, any of a group of plasma proteins that are kinin precursors.
30985	high molecular weight kininogen binding	F	Interacting selectively and non-covalently with a kininogen of high molecular mass.
30986	low molecular weight kininogen binding	F	Interacting selectively and non-covalently with a kininogen of low molecular mass.
30987	high molecular weight kininogen receptor binding	F	Interacting selectively and non-covalently with a high molecular weight kininogen receptor.
30988	high molecular weight kininogen receptor complex	C	A protein complex that acts as a receptor for high molecular weight kininogens. In humans, this receptor includes the CK1 and uPAR proteins.
30989	dynein-driven meiotic oscillatory nuclear movement	P	Oscillatory movement of the nucleus involved in meiosis I. This oscillatory movement is led by an astral microtubule array emanating from the spindle pole body, and driven by the microtubule motor cytoplasmic dynein.
30990	intraciliary transport particle	C	A nonmembrane-bound oligomeric protein complex that participates in bidirectional transport of molecules (cargo) along axonemal microtubules.
30991	intraciliary transport particle A	C	The smaller subcomplex of the intraciliary transport particle; characterized complexes have molecular weights of 710-760 kDa.
30992	intraciliary transport particle B	C	The larger subcomplex of the intraciliary transport particle; characterized complexes have molecular weights around 550 kDa.
30993	axonemal heterotrimeric kinesin-II complex	C	A kinesin complex found in eukaryotic axonemes that contains two distinct plus end-directed kinesin motor proteins and at least one accessory subunit, and that functions in the anterograde transport of molecules (cargo) from the basal body to the distal tip of the axoneme.
30994	primary cell septum disassembly	P	Dissolution of the primary septum during cell separation.
30995	cell septum edging catabolic process	P	The chemical reactions and pathways resulting in the dissolution of the septum edging during cell separation.
30997	regulation of centriole-centriole cohesion	P	Any process that modulates the extent to which the two centrioles within a centrosome remain tightly paired; may be mediated by the assembly and disassembly of a proteinaceous linker.
30998	linear element	C	A proteinaceous scaffold associated with S. pombe chromosomes during meiotic prophase. Linear elements have a structure related to but not equivalent to the synaptonemal complex.
30999	linear element assembly	P	The cell cycle process in which a proteinaceous scaffold, related to the synaptonemal complex, is assembled in association with S. pombe chromosomes during meiotic prophase.
31000	response to caffeine	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a caffeine stimulus. Caffeine is an alkaloid found in numerous plant species, where it acts as a natural pesticide that paralyzes and kills certain insects feeding upon them.
31001	response to brefeldin A	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a brefeldin A stimulus.
31002	actin rod	C	A cellular structure consisting of parallel, hexagonally arranged actin tubules, comprising filamentous actin and associated proteins. Found in the germinating spores of Dictyostelium discoideum.
31003	actin tubule	C	A cellular structure, approximately 13 nm in diameter, consisting of three actin filaments bundled together.
31004	potassium ion-transporting ATPase complex	C	Protein complex that carries out the reaction: ATP + H2O + K+(out) = ADP + phosphate + K+(in). It is a high affinity potassium uptake system. The E. coli complex consists of 4 proteins: KdpA is the potassium ion translocase, KdpB is the ATPase, and KdpC and KdpF seem to be involved in assembly and stabilization of the complex.
31005	filamin binding	F	Interacting selectively and non-covalently with a filamin, any member of a family of high molecular mass cytoskeletal proteins that crosslink actin filaments to form networks and stress fibers. Filamins contain an amino-terminal alpha-actinin-like actin binding domain, which is followed by a rod-domain composed of 4 to 24 100-residue repetitive segments including a carboxy-terminal dimerization domain.
31009	plastid ADPG pyrophosphorylase complex	C	An ADPG pyrophosphorylase complex found in a plastid.
31010	ISWI-type complex	C	Any nuclear protein complex that contains an ATPase subunit of the imitation switch (ISWI) family. ISWI ATPases are involved in assembling chromatin and in sliding and spacing nucleosomes to regulate transcription of nuclear RNA polymerases I, II, and III and also DNA replication, recombination and repair.
31011	Ino80 complex	C	A multisubunit protein complex that contains the Ino80p ATPase; exhibits chromatin remodeling activity and 3' to 5' DNA helicase activity.
31012	extracellular matrix	C	A structure lying external to one or more cells, which provides structural support for cells or tissues.
31013	troponin I binding	F	Interacting selectively and non-covalently with troponin I, the inhibitory subunit of the troponin complex.
31014	troponin T binding	F	Interacting selectively and non-covalently with troponin T, the tropomyosin-binding subunit of the troponin complex.
31016	pancreas development	P	The process whose specific outcome is the progression of the pancreas over time, from its formation to the mature structure. The pancreas is an endoderm derived structure that produces precursors of digestive enzymes and blood glucose regulating enzymes.
31017	exocrine pancreas development	P	The process whose specific outcome is the progression of the exocrine pancreas over time, from its formation to the mature structure. The exocrine pancreas produces and store zymogens of digestive enzymes, such as chymotrypsinogen and trypsinogen in the acinar cells.
31018	endocrine pancreas development	P	The process whose specific outcome is the progression of the endocrine pancreas over time, from its formation to the mature structure. The endocrine pancreas is made up of islet cells that produce insulin, glucagon and somatostatin.
31019	mitochondrial mRNA editing complex	C	An mRNA editing complex found in the mitochondrion. The best characterized example is that of Trypanosoma brucei, which catalyzes the insertion and deletion of uridylates.
31020	plastid mRNA editing complex	C	An mRNA editing complex found in a plastid.
31021	interphase microtubule organizing center	C	A microtubule organizing center found in interphase cells, which organize a longitudinal array of three to five MT bundles from the nuclear envelope during interphase. Each MT bundle is composed of two to seven MTs arranged in an antiparallel configuration, with the dynamic MT plus ends extending toward the cell tips and stable minus ends near the nucleus.
31022	nuclear migration along microfilament	P	The directed movement of the nucleus along microfilaments within the cell, mediated by motor proteins.
31023	microtubule organizing center organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a microtubule organizing center, a structure from which microtubules grow.
31024	interphase microtubule organizing center assembly	P	The aggregation, arrangement and bonding together of a set of components, including gamma-tubulin and other proteins, to form an interphase microtubule organizing center.
31025	equatorial microtubule organizing center disassembly	P	The process in which the equatorial microtubule organizing center is disassembled at the end of mitosis.
31026	glutamate synthase complex	C	A complex that possesses glutamate synthase activity.
31027	glutamate synthase complex (NADH)	C	A protein complex that in yeast consists of a large and a small subunit. Possesses glutamate synthase (NADH) activity.
31028	septation initiation signaling	P	The series of molecular signals, mediated by the small GTPase Ras, that results in the initiation of contraction of the contractile ring, at the beginning of cytokinesis and cell division by septum formation. The pathway coordinates chromosome segregation with mitotic exit and cytokinesis.
31029	regulation of septation initiation signaling	P	Any process that modulates the frequency, rate or extent of septation initiation signaling.
31030	negative regulation of septation initiation signaling	P	Any process that stops, prevents, or reduces the frequency, rate or extent of septation initiation signaling.
31031	positive regulation of septation initiation signaling	P	Any process that activates or increases the frequency, rate or extent of septation initiation signaling.
31032	actomyosin structure organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures containing both actin and myosin or paramyosin. The myosin may be organized into filaments.
31033	myosin filament organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a filament composed of myosin molecules.
31034	myosin filament assembly	P	The aggregation, arrangement and bonding together of a filament composed of myosin molecules.
31035	myosin filament disassembly	P	The disassembly of a filament composed of myosin molecules.
31036	myosin II filament assembly	P	The formation of a bipolar filament composed of myosin II molecules.
31037	myosin II filament disassembly	P	The disassembly of a bipolar filament composed of myosin II molecules.
31038	myosin II filament organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a bipolar filament composed of myosin II molecules.
31039	macronucleus	C	A membrane-bounded organelle of ciliated protozoan cells that contains polyploid copies of a portion of the cell's complete genome. Transcription of genes occurs in macronuclei. Some ciliate species may contain multiple macronuclei per cell.
31040	micronucleus	C	A membrane-bounded organelle of ciliated protozoan cells that contains a diploid copy of the cell's complete genome. Sections of contiguous sequence in the macronucleus are often interrupted by internal eliminated sequences (IES), and may be permuted, in micronuclei. Genic transcription is not found in micronuclei. Some ciliate species may contain multiple micronuclei per cell.
31041	O-glycan processing, core 5	P	The stepwise addition of carbohydrate or carbohydrate derivative residues to the initially added O-linked residue (usually GalNAc) to form the core 5 O-glycan structure, GalNAc-alpha-(1->3)-GalNAc.
31042	O-glycan processing, core 6	P	The stepwise addition of carbohydrate or carbohydrate derivative residues to the initially added O-linked residue (usually GalNAc) to form the core 6 O-glycan structure, GlcNAc-beta-(1->6)-GalNAc.
31043	O-glycan processing, core 7	P	The stepwise addition of carbohydrate or carbohydrate derivative residues to the initially added O-linked residue (usually GalNAc) to form the core 7 O-glycan structure, GalNAc-alpha-(1->6)-GalNAc.
31044	O-glycan processing, core 8	P	The stepwise addition of carbohydrate or carbohydrate derivative residues to the initially added O-linked residue (usually GalNAc) to form the core 8 O-glycan structure, Gal-alpha-(1->3)-GalNAc.
31045	dense core granule	C	Electron-dense organelle with a granular internal matrix; contains proteins destined to be secreted.
31047	gene silencing by RNA	P	Any process in which RNA molecules inactivate expression of target genes.
31048	chromatin silencing by small RNA	P	Repression of transcription by conversion of large regions of DNA into heterochromatin, directed by small RNAs sharing sequence identity to the repressed region.
31049	programmed DNA elimination	P	The DNA metabolic process in which micronuclear-limited sequences, internal eliminated sequences (IES) and breakage eliminated sequences (BES) are removed from the developing macronucleus (anlage) of a ciliate.
31050	dsRNA fragmentation	P	Cleavage of double-stranded RNA molecules by an RNaseIII-family enzyme to produce small RNAs (generally 20-30 nucleotides, depending on species) with biological function.
31051	scnRNA production	P	Cleavage of noncoding, double-stranded RNAs transcribed from the micronuclear genome to produce scnRNAs, small RNAs (~28 nucleotides) that direct the deletion of micronuclear-limited sequences from the developing macronuclear genome.
31052	chromosome breakage	P	Regulated cleavage of the developing macronuclear genome at a limited number of chromosome breakage sites (CBS). The macronuclear destined segment (MDS) sequence adjacent to the CBS (or separated from it by a BES) receives a macronuclear telomere following chromosome breakage.
31053	primary miRNA processing	P	Any process involved in the conversion of a primary microRNA transcript into a pre-microRNA molecule.
31054	pre-miRNA processing	P	Any process involved in the conversion of a pre-microRNA transcript into a mature microRNA molecule.
31055	chromatin remodeling at centromere	P	Dynamic structural changes in centromeric DNA.
31056	regulation of histone modification	P	Any process that modulates the frequency, rate or extent of the covalent alteration of a histone.
31057	negative regulation of histone modification	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the covalent alteration of a histone.
31058	positive regulation of histone modification	P	Any process that activates or increases the frequency, rate or extent of the covalent alteration of a histone.
31059	histone deacetylation at centromere	P	The removal of acetyl groups from histones in centromeric DNA.
31060	regulation of histone methylation	P	Any process that modulates the frequency, rate or extent of the covalent addition of methyl groups to histones.
31061	negative regulation of histone methylation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the covalent addition of methyl groups to histones.
31062	positive regulation of histone methylation	P	Any process that activates or increases the frequency, rate or extent of the covalent addition of methyl groups to histones.
31063	regulation of histone deacetylation	P	Any process that modulates the frequency, rate or extent of the removal of acetyl groups from histones.
31064	negative regulation of histone deacetylation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the removal of acetyl groups from histones.
31065	positive regulation of histone deacetylation	P	Any process that activates or increases the frequency, rate or extent of the removal of acetyl groups from histones.
31066	regulation of histone deacetylation at centromere	P	Any process that modulates the frequency, rate or extent of the removal of acetyl groups from histones in centromeric DNA.
31067	negative regulation of histone deacetylation at centromere	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the removal of acetyl groups to histones in centromeric DNA.
31068	positive regulation of histone deacetylation at centromere	P	Any process that activates or increases the frequency, rate or extent of the removal of acetyl groups from histones in centromeric DNA.
31069	hair follicle morphogenesis	P	The process in which the anatomical structures of the hair follicle are generated and organized.
31070	intronic snoRNA processing	P	The biogenesis of a snoRNA molecule which resides within, and is processed from, the intron of a pre-mRNA.
31071	cysteine desulfurase activity	F	Catalysis of the reaction: L-cysteine + [enzyme]-cysteine = L-alanine + [enzyme]-S-sulfanylcysteine.
31072	heat shock protein binding	F	Interacting selectively and non-covalently with a heat shock protein, any protein synthesized or activated in response to heat shock.
31073	cholesterol 26-hydroxylase activity	F	Catalysis of the hydroxylation of cholesterol at position 26 of the side chain, to produce 26-hydroxycholesterol.
31074	nucleocytoplasmic shuttling complex	C	Any complex that acts to move proteins or RNAs into or out of the nucleus through nuclear pores.
31076	embryonic camera-type eye development	P	The process occurring during the embryonic phase whose specific outcome is the progression of the eye over time, from its formation to the mature structure.
31077	post-embryonic camera-type eye development	P	The process occurring during the post-embryonic phase whose specific outcome is the progression of the camera-type eye over time, from its formation to the mature structure.
31078	histone deacetylase activity (H3-K14 specific)	F	Catalysis of the reaction: histone H3 N6-acetyl-L-lysine (position 14) + H2O = histone H3 L-lysine (position 14) + acetate. This reaction represents the removal of an acetyl group from lysine at position 14 of the histone H3 protein.
31080	nuclear pore outer ring	C	A subcomplex of the nuclear pore complex (NPC) that forms the outer rings of the core scaffold, a lattice-like structure that gives the NPC its shape and strength. In S. cerevisiae, the two outer rings each contain multiple copies of the following proteins: Nup133p, Nup120p, Nup145Cp, Nup85p, Nup84p, Seh1p, and Sec13p. In vertebrates, the two outer rings each contain multiple copies of the following proteins: Nup133, Nup160, Nup96, Nup75, Nup107, Seh1, Sec13, Nup43, Nup37, and ALADIN. Components are arranged in 8-fold symmetrical 'spokes' around the central transport channel. A single 'spoke', can be isolated and is sometimes referred to as the Nup84 complex (S. cerevisiae) or the Nup107-160 complex (vertebrates).
31081	nuclear pore distribution	P	Any process that establishes the spatial arrangement of nuclear pores within the nuclear envelope.
31082	BLOC complex	C	Any of several protein complexes required for the biogenesis of specialized organelles of the endosomal-lysosomal system, such as melanosomes, platelet dense granules, and other related organelles; acronym for biogenesis of lysosomal-related organelles complex.
31083	BLOC-1 complex	C	A protein complex required for the biogenesis of specialized organelles of the endosomal-lysosomal system, such as melanosomes and platelet dense granules. Many of the protein subunits are conserved between mouse and human; the mouse complex contains the Pallidin, Muted, Cappuccino, Dysbindin, Snapin, BLOS1, BLOS2, AND BLOS3 proteins.
31084	BLOC-2 complex	C	A protein complex required for the biogenesis of specialized organelles of the endosomal-lysosomal system, such as melanosomes and platelet dense granules. The human complex contains the Hps3, Hps5, and Hps6 proteins; the mouse complex contains ru2 and ru.
31085	BLOC-3 complex	C	A protein complex required for the biogenesis of specialized organelles of the endosomal-lysosomal system, such as melanosomes and platelet dense granules. The human complex contains the Hps1 and Hps4 proteins.
31086	nuclear-transcribed mRNA catabolic process, deadenylation-independent decay	P	A pathway of degradation of nuclear-transcribed mRNAs that proceeds through a series of steps that is independent of deadenylation, but requires decapping followed by transcript decay, and that can regulate mRNA stability.
31087	deadenylation-independent decapping of nuclear-transcribed mRNA	P	Cleavage of the 5'-cap of a nuclear-transcribed mRNA that is independent of poly(A) tail shortening.
31088	platelet dense granule membrane	C	The lipid bilayer surrounding the platelet dense granule.
31089	platelet dense granule lumen	C	The volume enclosed by the membrane of the platelet dense granule.
31090	organelle membrane	C	A membrane that is one of the two lipid bilayers of an organelle envelope or the outermost membrane of single membrane bound organelle.
31091	platelet alpha granule	C	A secretory organelle found in blood platelets, which is unique in that it exhibits further compartmentalization and acquires its protein content via two distinct mechanisms: (1) biosynthesis predominantly at the megakaryocyte (MK) level (with some vestigial platelet synthesis) (e.g. platelet factor 4) and (2) endocytosis and pinocytosis at both the MK and circulating platelet levels (e.g. fibrinogen (Fg) and IgG).
31092	platelet alpha granule membrane	C	The lipid bilayer surrounding the platelet alpha granule.
31093	platelet alpha granule lumen	C	The volume enclosed by the membrane of the platelet alpha granule.
31094	platelet dense tubular network	C	A network of membrane-bounded compartments found in blood platelets, where they regulate platelet activation by sequestering or releasing calcium. The dense tubular network exists as thin elongated membranes in resting platelets, and undergoes a major ultrastructural change, to a rounded vesicular form, upon addition of thrombin.
31095	platelet dense tubular network membrane	C	The lipid bilayer surrounding the platelet dense tubular network.
31096	platelet dense tubular network lumen	C	The volume enclosed by the membranes of the platelet dense tubular network.
31097	medial cortex	C	A medial cortical band overlaying the nucleus which acts as a landmark for contractile ring positioning and plays a role in cell cycle regulation.
31098	stress-activated protein kinase signaling cascade	P	A series of molecular signals in which a stress-activated protein kinase (SAPK) cascade relays one or more of the signals.
31099	regeneration	P	The regrowth of a lost or destroyed body part, such as an organ or tissue. This process may occur via renewal, repair, and/or growth alone (i.e. increase in size or mass).
31100	animal organ regeneration	P	The regrowth of a lost or destroyed animal organ.
31101	fin regeneration	P	The regrowth of fin tissue following its loss or destruction.
31102	neuron projection regeneration	P	The regrowth of neuronal processes such as axons or dendrites in response to their loss or damage.
31103	axon regeneration	P	The regrowth of axons following their loss or damage.
31104	dendrite regeneration	P	The regrowth of dendrites in response to their loss or damage.
31105	septin complex	C	A protein complex containing septins. Typically, these complexes contain multiple septins and are oligomeric.
31106	septin ring organization	P	Control of the formation, spatial distribution, and breakdown of the septin ring.
31107	septin ring disassembly	P	The controlled breakdown of a septin ring.
31108	holo-[acyl-carrier-protein] biosynthetic process	P	The chemical reactions and pathways resulting in the formation of holo-[acyl-carrier protein].
31109	microtubule polymerization or depolymerization	P	Assembly or disassembly of microtubules by the addition or removal of tubulin heterodimers from a microtubule.
31110	regulation of microtubule polymerization or depolymerization	P	Any process that modulates the frequency, rate or extent of microtubule polymerization or depolymerization by the addition or removal of tubulin heterodimers from a microtubule.
31111	negative regulation of microtubule polymerization or depolymerization	P	Any process that stops, prevents, or reduces the frequency, rate or extent of microtubule polymerization or depolymerization.
31112	positive regulation of microtubule polymerization or depolymerization	P	Any process that activates or increases the frequency, rate or extent of microtubule polymerization or depolymerization.
31113	regulation of microtubule polymerization	P	Any process that modulates the frequency, rate or extent of microtubule polymerization.
31114	regulation of microtubule depolymerization	P	Any process that modulates the frequency, rate or extent of microtubule depolymerization.
31115	negative regulation of microtubule polymerization	P	Any process that stops, prevents, or reduces the frequency, rate or extent of microtubule polymerization.
31116	positive regulation of microtubule polymerization	P	Any process that activates or increases the frequency, rate or extent of microtubule polymerization.
31117	positive regulation of microtubule depolymerization	P	Any process that activates or increases the frequency, rate or extent of microtubule depolymerization.
31118	rRNA pseudouridine synthesis	P	The intramolecular conversion of uridine to pseudouridine in an rRNA molecule.
31119	tRNA pseudouridine synthesis	P	The intramolecular conversion of uridine to pseudouridine in a tRNA molecule.
31120	snRNA pseudouridine synthesis	P	The intramolecular conversion of uridine to pseudouridine in an snRNA molecule.
31121	equatorial microtubule organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of structures formed of microtubules and associated proteins at the midpoint of a cell.
31122	cytoplasmic microtubule organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of structures formed of microtubules and associated proteins in the cytoplasm of a cell.
31123	RNA 3'-end processing	P	Any process involved in forming the mature 3' end of an RNA molecule.
31124	mRNA 3'-end processing	P	Any process involved in forming the mature 3' end of an mRNA molecule.
31125	rRNA 3'-end processing	P	Any process involved in forming the mature 3' end of an rRNA molecule.
31126	snoRNA 3'-end processing	P	Any process involved in forming the mature 3' end of a snoRNA molecule.
31127	alpha-(1,2)-fucosyltransferase activity	F	Catalysis of the transfer of an L-fucosyl group from GDP-beta-L-fucose to an acceptor molecule to form an alpha-(1->2) linkage.
31128	developmental induction	P	A developmental process involving two tissues in which one tissue (the inducer) produces a signal that directs cell fate commitment of cells in the second tissue (the responder).
31129	inductive cell-cell signaling	P	Signaling at short range between cells of different ancestry and developmental potential that results in one cell or group of cells effecting a developmental change in the other. This is often done by secretion of proteins by one cell which affects the neighboring cells and causes them to adopt a certain fate.
31130	creation of an inductive signal	P	The process in which one cell or group of cells sends a signal over a short range to another cell or group of cells of different ancestry and developmental potential, thereby effecting a developmental change in the latter.
31131	reception of an inductive signal	P	The process in which one cell or group of cells receives, transduces, and responds to a signal generated by another cell or group of cells of different ancestry and developmental potential, such that the recipient cell(s) undergo a developmental change.
31132	serine 3-dehydrogenase activity	F	Catalysis of the reaction: L-serine + NADP(+) = L-alpha-formylglycine + 2 H(+) + NADPH.
31133	regulation of axon diameter	P	Any process that modulates the rate, direction or extent of axon growth such that the correct diameter is attained and maintained.
31134	sister chromatid biorientation	P	The cell cycle process in which sister chromatids establish stable attachments to microtubules emanating from opposite spindle poles.
31135	negative regulation of conjugation	P	Any process that decreases the rate of conjugation.
31136	positive regulation of conjugation	P	Any process that increases the rate or frequency of conjugation.
31137	regulation of conjugation with cellular fusion	P	Any process that modulates the rate or frequency of conjugation with cellular fusion.
31138	negative regulation of conjugation with cellular fusion	P	Any process that decreases the rate or frequency of conjugation with cellular fusion.
31139	positive regulation of conjugation with cellular fusion	P	Any process that increases the rate or frequency of conjugation with cellular fusion.
31140	induction of conjugation upon nutrient starvation	P	The process in which a cell initiates conjugation with cellular fusion upon starvation for one or more nutrients.
31141	induction of conjugation upon carbon starvation	P	The process in which a cell initiates conjugation with cellular fusion upon carbon starvation.
31142	induction of conjugation upon nitrogen starvation	P	The process in which a cell initiates conjugation with cellular fusion upon nitrogen starvation.
31143	pseudopodium	C	A temporary protrusion or retractile process of a cell, associated with flowing movements of the protoplasm, and serving for locomotion and feeding.
31144	proteasome localization	P	Any process in which the proteasome is transported to, or maintained in, a specific location.
31145	anaphase-promoting complex-dependent catabolic process	P	The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, with ubiquitin-protein ligation catalyzed by the anaphase-promoting complex, and mediated by the proteasome.
31146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	P	The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, with ubiquitin-protein ligation catalyzed by an SCF (Skp1/Cul1/F-box protein) complex, and mediated by the proteasome.
31147	1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one metabolic process	P	The chemical reactions and pathways involving 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one, also known as DIF-1, differentiation-inducing factor-1. DIF-1 is a secreted chlorinated molecule that controls cell fate during development of Dictyostelium cells.
31148	DIF-1 biosynthetic process	P	The chemical reactions and pathways resulting in the formation of 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one, also known as DIF-1, differentiation-inducing factor-1. DIF-1 is a secreted chlorinated molecule that controls cell fate during development of Dictyostelium cells.
31149	sorocarp stalk cell differentiation	P	The process in which a relatively unspecialized cell acquires specialized features of a sorocarp stalk cell, any of the cellulose-covered cells that form the stalk of a sorocarp. An example of this process is found in Dictyostelium discoideum.
31150	sorocarp stalk development	P	The process whose specific outcome is the progression of the sorocarp stalk over time, from its formation to the mature structure. The sorocarp stalk is a tubular structure that consists of cellulose-covered cells stacked on top of each other and surrounded by an acellular stalk tube composed of cellulose and glycoprotein. An example of this process is found in Dictyostelium discoideum.
31151	histone methyltransferase activity (H3-K79 specific)	F	Catalysis of the reaction: S-adenosyl-L-methionine + histone H3 L-lysine (position 79) = S-adenosyl-L-homocysteine + histone H3 N6-methyl-L-lysine (position 79). This reaction is the addition of a methyl group onto lysine at position 79 of the histone H3 protein.
31152	aggregation involved in sorocarp development	P	The process whose specific outcome is the progression of the aggregate over time, from its formation to the point when a slug is formed. Aggregate development begins in response to starvation and continues by the chemoattractant-mediated movement of cells toward each other. The aggregate is a multicellular structure that gives rise to the slug.
31153	slug development involved in sorocarp development	P	The process whose specific outcome is the progression of the slug over time, from its formation to the mature structure. Slug development begins when the aggregate rises upwards to form a finger-shaped structure and ends when culmination begins. Slug development begins after aggregation and ends before culmination in sorocarp development.
31154	culmination involved in sorocarp development	P	The process whose specific outcome is the progression of the culminant over time, from its formation to the mature structure. Culmination begins with a morphogenetic change of the finger-like or migratory slug giving rise to an organized structure containing a stalk and a sorus. This process is the final stage of sorocarp development.
31155	regulation of reproductive fruiting body development	P	Any process that modulates the frequency, rate or extent of reproductive fruiting body development.
31156	regulation of sorocarp development	P	Any process that modulates the frequency, rate or extent of sorocarp development. An example of this process is found in Dictyostelium discoideum.
31157	regulation of aggregate size involved in sorocarp development	P	Any process that modulates the size of the aggregate formed during sorocarp formation.
31158	negative regulation of aggregate size involved in sorocarp development	P	Any process that decreases the size of the aggregate formed during sorocarp formation.
31159	positive regulation of aggregate size involved in sorocarp development	P	Any process that increases the size of the aggregate formed during sorocarp formation.
31160	spore wall	C	The specialized envelope lying outside the cell membrane of a spore.
31161	phosphatidylinositol catabolic process	P	The chemical reactions and pathways resulting in the breakdown of phosphatidylinositol, any glycophospholipid with its sn-glycerol 3-phosphate residue is esterified to the 1-hydroxyl group of 1D-myo-inositol.
31162	sulfur incorporation into metallo-sulfur cluster	P	The incorporation of exogenous sulfur into a metallo-sulfur cluster.
31163	metallo-sulfur cluster assembly	P	The incorporation of a metal and exogenous sulfur into a metallo-sulfur cluster.
31164	contractile vacuolar membrane	C	The lipid bilayer surrounding the contractile vacuole.
31165	integral component of contractile vacuolar membrane	C	The component of the contractile vacuolar membrane consisting of gene products that have some part that penetrates at least one leaflet of the membrane bilayer. This component includes gene products that are buried in the bilayer with no exposure outside the bilayer.
31166	integral component of vacuolar membrane	C	The component of the vacuolar membrane consisting of gene products and protein complexes that have some part that penetrates at least one leaflet of the membrane bilayer. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer.
31167	rRNA methylation	P	The posttranscriptional addition of methyl groups to specific residues in an rRNA molecule.
31168	ferrichrome metabolic process	P	The chemical reactions and pathways involving a ferrichrome. Ferrichromes are any of a group of growth-promoting Fe(III) chelates formed by various genera of microfungi. They are homodetic cyclic hexapeptides made up of a tripeptide of glycine (or other small neutral amino acids) and a tripeptide of an N'acyl-N4-hydroxy-L-ornithine.
31169	ferrichrome biosynthetic process	P	The chemical reactions and pathways resulting in the formation of a ferrichrome. Ferrichromes are any of a group of growth-promoting Fe(III) chelates formed by various genera of microfungi. They are homodetic cyclic hexapeptides made up of a tripeptide of glycine (or other small neutral amino acids) and a tripeptide of an N'acyl-N4-hydroxy-L-ornithine.
31170	ferricrocin metabolic process	P	The chemical reactions and pathways involving ferricrocin, a cyclic hexapeptide siderophore with the structure Gly-Ser-Gly-(N5-acetyl-N5-hydroxyornithine)3.
31171	ferricrocin biosynthetic process	P	The chemical reactions and pathways resulting in the formation of ferricrocin, a cyclic hexapeptide siderophore with the structure Gly-Ser-Gly-(N5-acetyl-N5-hydroxyornithine)3.
31172	ornithine N5-monooxygenase activity	F	Catalysis of the reaction: L-ornithine + O2 + H+ = N5-hydroxy-L-ornithine + H2O.
31173	otolith mineralization completed early in development	P	The formation of otoliths during embryogenesis with completion in early postembryonic development. Formation occurs by precipitation of specific crystal forms of calcium carbonate around an organic core of extracellular matrix proteins. Otoconia (otoliths) are small (~10 micron) dense extracellular particles present in the otolith end organs of the vertebrate inner ear.
31174	lifelong otolith mineralization	P	The formation and growth of otoliths throughout the life of the organism. Otoliths are the large extracellular ear-stones of the fish inner ear, produced by precipitation of specific crystal forms of calcium carbonate on organic matrices. The otolith enlarges throughout the life of the fish, as layers of calcium carbonate are added.
31175	neuron projection development	P	The process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites).
31176	endo-1,4-beta-xylanase activity	F	Catalysis of the endohydrolysis of (1->4)-beta-D-xylosidic linkages in xylans.
31177	phosphopantetheine binding	F	Interacting selectively and non-covalently with phosphopantetheine, the vitamin pantetheine 4'-(dihydrogen phosphate).
31179	peptide modification	P	The covalent alteration of one or more amino acid residues within a peptide, resulting in a change in the properties of that peptide.
31201	SNARE complex	C	A protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers. One well-characterized example is the neuronal SNARE complex formed of synaptobrevin 2, syntaxin 1a, and SNAP-25.
31203	posttranslational protein targeting to membrane, docking	P	The process in which the signal sequence of a translated protein binds to and forms a complex with the Sec complex.
31204	posttranslational protein targeting to membrane, translocation	P	The process in which a protein translocates through the ER membrane posttranslationally.
31205	endoplasmic reticulum Sec complex	C	An endoplasmic reticulum membrane-associated complex involved in the translocation of proteins that are targeted to the ER. In yeast, this complex consists of two subcomplexes, namely, the Sec61 complex and the Sec62/Sec63 complex.
31207	Sec62/Sec63 complex	C	A protein complex involved in the posttranslational targeting of proteins to the ER. In yeast, it is a tetrameric complex consisting of Sec62p, Sec63p, Sec71p and Sec72p.
31208	POZ domain binding	F	Interacting selectively and non-covalently with a POZ (poxvirus and zinc finger) domain of a protein, a protein-protein interaction domain found in many transcription factors.
31209	SCAR complex	C	A pentameric complex that includes orthologues of human PIR121, Nap1, Abi, SCAR, and HSPC300 and regulates actin polymerization and/or depolymerization through small GTPase mediated signal transduction.
31210	phosphatidylcholine binding	F	Interacting selectively and non-covalently with phosphatidylcholine, a class of glycophospholipids in which a phosphatidyl group is esterified to the hydroxyl group of choline.
31211	endoplasmic reticulum palmitoyltransferase complex	C	A complex of the endoplasmic reticulum that catalyzes S-palmitoylation, the addition of palmitate (C16:0) or other long-chain fatty acids to proteins at a cysteine residue.
31213	RSF complex	C	An ISWI complex that contains an ATPase subunit of the ISWI family (SNF2H in mammals) and an RSF1 homolog. It mediates nucleosome deposition and generates regularly spaced nucleosome arrays. In mammals, RSF is involved in regulation of transcription from RNA polymerase II promoters).
31214	biomineral tissue development	P	Formation of hard tissues that consist mainly of inorganic compounds, and also contain a small amounts of organic matrices that are believed to play important roles in their formation.
31215	shell calcification	P	The precipitation of calcium carbonate onto the organic matrix of a shell, such as a mollusc shell.
31216	neopullulanase activity	F	Catalysis of the hydrolysis of pullulan to panose (6-alpha-D-glucosylmaltose).
31217	glucan 1,4-beta-glucosidase activity	F	Catalysis of the hydrolysis of (1->4) linkages in (1->4)-beta-D-glucans, to remove successive glucose units.
31218	arabinogalactan endo-1,4-beta-galactosidase activity	F	Catalysis of the endohydrolysis of (1->4)-beta-D-galactosidic linkages in arabinogalactans.
31219	levanase activity	F	Catalysis of the random hydrolysis of 2,6-beta-D-fructofuranosidic linkages in 2,6-beta-D-fructans (levans) containing more than 3 fructose units.
31220	maltodextrin phosphorylase activity	F	Catalysis of the reaction: maltodextrin = glucose-1-phosphate.
31221	arabinan metabolic process	P	The chemical reactions and pathways involving arabinan, a polysaccharide composed of arabinose residues.
31222	arabinan catabolic process	P	The chemical reactions and pathways resulting in the breakdown of arabinan, a polysaccharide composed of arabinose residues.
31223	auditory behavior	P	The behavior of an organism in response to a sound.
31224	intrinsic component of membrane	C	The component of a membrane consisting of the gene products having some covalently attached portion, for example part of a peptide sequence or some other covalently attached group such as a GPI anchor, which spans or is embedded in one or both leaflets of the membrane.
31225	anchored component of membrane	C	The component of a membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping.
31226	intrinsic component of plasma membrane	C	The component of the plasma membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.
31227	intrinsic component of endoplasmic reticulum membrane	C	The component of the endoplasmic reticulum membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.
31228	intrinsic component of Golgi membrane	C	The component of the Golgi membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.
31229	intrinsic component of nuclear inner membrane	C	The component of the nuclear inner membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.
31230	intrinsic component of cell outer membrane	C	The component of the cell outer membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.
31231	intrinsic component of peroxisomal membrane	C	The component of the peroxisomal membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.
31232	extrinsic component of external side of plasma membrane	C	The component of a plasma membrane consisting of gene products and protein complexes that are loosely bound to its external surface, but not integrated into the hydrophobic region.
31233	intrinsic component of external side of plasma membrane	C	The component of a plasma membrane consisting of gene products and protein complexes that penetrate the external side of the plasma membrane only, either directly or via some covalently attached hydrophobic anchor.
31234	extrinsic component of cytoplasmic side of plasma membrane	C	The component of a plasma membrane consisting of gene products and protein complexes that are loosely bound to its cytoplasmic surface, but not integrated into the hydrophobic region.
31235	intrinsic component of the cytoplasmic side of the plasma membrane	C	The component of a plasma membrane consisting of gene products and protein complexes that have some covalently attached part (e.g. peptide sequence or GPI anchor) which is embedded in the cytoplasmic side of the plasma membrane only.
31236	extrinsic component of periplasmic side of plasma membrane	C	The component of a plasma membrane consisting of gene products and protein complexes that are loosely bound to its periplasmic surface, but not integrated into the hydrophobic region.
31237	intrinsic component of periplasmic side of plasma membrane	C	The component of a plasma membrane consisting of gene products and protein complexes that penetrate the periplasmic side of the plasma membrane only, either directly or via some covalently attached hydrophobic anchor.
31240	external side of cell outer membrane	C	The side of the outer membrane that is opposite to the side that faces the periplasm of the cell.
31241	periplasmic side of cell outer membrane	C	The side (leaflet) of the outer membrane that faces the periplasm of the cell.
31242	extrinsic component of external side of cell outer membrane	C	The component of a cell outer membrane consisting of gene products and protein complexes that are loosely bound to its external surface, but not integrated into the hydrophobic region.
31243	intrinsic component of external side of cell outer membrane	C	The component of the cell outer membrane consisting of the gene products and protein complexes that penetrate the external side of the cell outer membrane only, either directly or via some covalently attached hydrophobic anchor.
31244	extrinsic component of cell outer membrane	C	The component of the cell outer membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
31245	extrinsic component of periplasmic side of cell outer membrane	C	The component of the cell outer membrane consisting of gene products and protein complexes that are loosely bound to periplasmic surface, but not integrated into the hydrophobic region.
31246	intrinsic component of periplasmic side of cell outer membrane	C	The component of the cell outer membrane consisting of the gene products that that penetrate the periplasmic side of the cell outer membrane only, either directly or via some covalently attached hydrophobic anchor.
31247	actin rod assembly	P	The assembly of actin rods, a cellular structure consisting of parallel, hexagonally arranged actin tubules.
31248	protein acetyltransferase complex	C	A complex that catalyzes the transfer of an acetyl group to a protein acceptor molecule.
31249	denatured protein binding	F	Interacting selectively and non-covalently with denatured proteins.
31250	anaerobic ribonucleoside-triphosphate reductase complex	C	An enzyme complex composed of 4 subunits, 2 copies of the large protein (nrdD in E. coli) and 2 copies of the small protein (nrdG in E. coli). It catalyzes the generation of 2'deoxyribonucleotides under anaerobic growth conditions. The larger subunit is the catalytic unit that is activated by the smaller iron-binding subunit.
31251	PAN complex	C	A complex that possesses poly(A)-specific ribonuclease activity; catalyzes the message-specific shortening of mRNA poly(A) tails. Contains at least two subunits, known as Pan2p and Pan3p in Saccharomyces.
31252	cell leading edge	C	The area of a motile cell closest to the direction of movement.
31253	cell projection membrane	C	The portion of the plasma membrane surrounding a cell surface projection.
31254	cell trailing edge	C	The area of a motile cell opposite to the direction of movement.
31255	lateral part of motile cell	C	The area of a motile cell perpendicular to the direction of movement.
31256	leading edge membrane	C	The portion of the plasma membrane surrounding the leading edge of a motile cell.
31257	cell trailing edge membrane	C	The portion of the plasma membrane surrounding the trailing edge of a motile cell.
31258	lamellipodium membrane	C	The portion of the plasma membrane surrounding a lamellipodium.
31259	uropod membrane	C	The portion of the plasma membrane surrounding a uropod.
31260	pseudopodium membrane	C	The portion of the plasma membrane surrounding a pseudopodium.
31261	DNA replication preinitiation complex	C	A protein-DNA complex assembled at eukaryotic DNA replication origins immediately prior to the initiation of DNA replication. The preinitiation complex is formed by the assembly of additional proteins onto an existing prereplicative complex. In budding yeast, the additional proteins include Cdc45p, Sld2p, Sld3p, Dpb11p, DNA polymerases, and others; in fission yeast the GINS complex is present.
31262	Ndc80 complex	C	A protein complex conserved among eukaryotes that forms part of the kinetochore and plays an essential role in forming stable kinetochore-microtubule attachments. The complex contains proteins known in several species, including budding and fission yeasts, as Ndc80p, Nuf2p, Spc24p, and Spc25p. In vertebrates it is part of the outer plate of the kinetochore.
31263	amine-transporting ATPase activity	F	Catalysis of the reaction: ATP + H2O + amine(out) = ADP + phosphate + amine(in).
31264	death-inducing signaling complex	C	A protein complex formed by the association of signaling proteins with a death receptor upon ligand binding. The complex includes procaspases and death domain-containing proteins in addition to the ligand-bound receptor, and may control the activation of caspases 8 and 10.
31265	CD95 death-inducing signaling complex	C	A protein complex formed upon binding of Fas/CD95/APO-1 to its ligand. The complex includes FADD/Mort1, procaspase-8/10 and c-FLIP in addition to the ligand-bound receptor.
31266	TRAIL death-inducing signaling complex	C	A protein complex formed upon binding of TRAIL to its ligand. The complex includes FADD/Mort1 and procaspase-8 addition to the ligand-bound receptor.
31267	small GTPase binding	F	Interacting selectively and non-covalently with a small monomeric GTPase.
31268	pseudopodium organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a pseudopodium, a temporary protrusion or retractile process of a cell, associated with cellular movement.
31269	pseudopodium assembly	P	The assembly of a pseudopodium by rearrangement of the actin cytoskeleton and overlying membrane.
31270	pseudopodium retraction	P	The myosin-based contraction and retraction of the pseudopodium.
31271	lateral pseudopodium assembly	P	The extension of a pseudopodium from the lateral area of a cell.
31272	regulation of pseudopodium assembly	P	Any process that modulates the frequency, rate or extent of the assembly of pseudopodia.
31273	negative regulation of pseudopodium assembly	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the assembly of pseudopodia.
31274	positive regulation of pseudopodium assembly	P	Any process that activates or increases the frequency, rate or extent of the assembly of pseudopodia.
31275	regulation of lateral pseudopodium assembly	P	Any process that modulates the frequency, rate or extent of the assembly of pseudopodia from the lateral side of the cell.
31276	negative regulation of lateral pseudopodium assembly	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the assembly of pseudopodia from the lateral side of the cell.
31277	positive regulation of lateral pseudopodium assembly	P	Any process that activates or increases the frequency, rate or extent of the assembly of pseudopodia from the lateral side of the cell.
31278	alpha-1,2-galactosyltransferase activity	F	Catalysis of the transfer of a galactose residue from a donor molecule, such as GDP-galactose or UDP-galactose, to an oligosaccharide, forming an alpha-1,2-linkage.
31279	regulation of cyclase activity	P	Any process that modulates the frequency, rate or extent of cyclase activity.
31280	negative regulation of cyclase activity	P	Any process that stops or reduces the activity of a cyclase.
31281	positive regulation of cyclase activity	P	Any process that activates or increases the activity of a cyclase.
31282	regulation of guanylate cyclase activity	P	Any process that modulates the frequency, rate or extent of guanylate cyclase activity.
31283	negative regulation of guanylate cyclase activity	P	Any process that stops, prevents, or reduces the frequency, rate or extent of guanylate cyclase activity.
31284	positive regulation of guanylate cyclase activity	P	Any process that activates or increases the frequency, rate or extent of guanylate cyclase activity.
31285	regulation of sorocarp stalk cell differentiation	P	Any process that modulates the frequency, rate or extent of sorocarp stalk cell differentiation. An example of this process is found in Dictyostelium discoideum.
31286	negative regulation of sorocarp stalk cell differentiation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of sorocarp stalk cell differentiation. An example of this process is found in Dictyostelium discoideum.
31287	positive regulation of sorocarp stalk cell differentiation	P	Any process that activates or increases the frequency, rate or extent of sorocarp stalk cell differentiation. An example of this process is found in Dictyostelium discoideum.
31288	sorocarp morphogenesis	P	The process in which the sorocarp is generated and organized. An example of this process is found in Dictyostelium discoideum.
31289	actin phosphorylation	P	The transfer of one or more phosphate groups to an actin molecule.
31290	retinal ganglion cell axon guidance	P	The process in which the migration of an axon growth cone of a retinal ganglion cell (RGC) is directed to its target in the brain in response to a combination of attractive and repulsive cues.
31291	Ran protein signal transduction	P	A series of molecular signals within the cell that are mediated by a member of the Ran family of proteins switching to a GTP-bound active state.
31292	gene conversion at mating-type locus, DNA double-strand break processing	P	The 5' to 3' exonucleolytic resection of the DNA at the site of the break at the mating-type locus to form a 3' single-strand DNA overhang.
31293	membrane protein intracellular domain proteolysis	P	The proteolytic cleavage of a transmembrane protein leading to the release of an intracellular domain.
31294	lymphocyte costimulation	P	The process of providing, via surface-bound receptor-ligand pairs, a second, antigen-independent, signal in addition to that provided by the B- or T cell receptor to augment B- or T cell activation.
31295	T cell costimulation	P	The process of providing, via surface-bound receptor-ligand pairs, a second, antigen-independent, signal in addition to that provided by the T cell receptor to augment T cell activation.
31296	B cell costimulation	P	The process of providing, via surface-bound receptor-ligand pairs, a second, antigen-independent, signal in addition to that provided by the B cell receptor to augment B cell activation.
31297	replication fork processing	P	The process in which a DNA replication fork that has stalled is restored to a functional state and replication is restarted. The stalling may be due to DNA damage, DNA secondary structure, bound proteins, dNTP shortage, or other causes.
31298	replication fork protection complex	C	A protein complex conserved in eukaryotes and associated with the replication fork; the complex stabilizes stalled replication forks and is thought to be involved in coordinating leading- and lagging-strand synthesis and in replication checkpoint signaling.
31299	taurine-pyruvate aminotransferase activity	F	Catalysis of the reaction: pyruvate + taurine = L-alanine + sulfoacetaldehyde.
31300	intrinsic component of organelle membrane	C	The component of the organelle membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.
31301	integral component of organelle membrane	C	The component of the organelle membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
31302	intrinsic component of endosome membrane	C	The component of the endosome membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.
31303	integral component of endosome membrane	C	The component of the endosome membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
31304	intrinsic component of mitochondrial inner membrane	C	The component of the mitochondrial inner membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.
31305	integral component of mitochondrial inner membrane	C	The component of the mitochondrial inner membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
31306	intrinsic component of mitochondrial outer membrane	C	The component of the mitochondrial outer membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.
31307	integral component of mitochondrial outer membrane	C	The component of the mitochondrial outer membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
31308	intrinsic component of nuclear outer membrane	C	The component of the nuclear outer membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.
31309	integral component of nuclear outer membrane	C	The component of the nuclear outer membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
31310	intrinsic component of vacuolar membrane	C	The component of the vacuolar membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.
31311	intrinsic component of contractile vacuolar membrane	C	The component of the contractile vacuolar membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.
31312	extrinsic component of organelle membrane	C	The component of an organelle membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
31313	extrinsic component of endosome membrane	C	The component of an endosome membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
31314	extrinsic component of mitochondrial inner membrane	C	The component of mitochondrial inner membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
31315	extrinsic component of mitochondrial outer membrane	C	The component of a mitochondrial outer membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
31316	extrinsic component of nuclear outer membrane	C	The component of a nuclear outer membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
31317	tripartite ATP-independent periplasmic transporter complex	C	A complex consisting of two membrane proteins and one extracytoplasmic solute receptor. Such transporters transport a variety of substrates without direct ATP power, instead using energy from ion gradients.
31318	detection of folic acid	P	The series of events in which a folic acid stimulus is received by a cell and converted into a molecular signal.
31319	detection of cAMP	P	The series of events in which a cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate) stimulus is received by a cell and converted into a molecular signal; cAMP is the nucleotide cyclic AMP.
31320	hexitol dehydrogenase activity	F	Catalysis of the reaction: hexitol + acceptor = hexose + reduced acceptor.
31321	ascospore-type prospore assembly	P	During ascospore formation, the process in which each haploid nucleus becomes encapsulated by a double membrane.
31322	ascospore-type prospore-specific spindle pole body remodeling	P	A spindle pole body (SPB) organization process that takes place during the second meiotic division during ascospore formation and results in the structural reorganization of the SPB; includes the recruitment of sporulation-specific proteins to the outer plaque to form the meiotic outer plaque (MOP).
31323	regulation of cellular metabolic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances.
31324	negative regulation of cellular metabolic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances.
31325	positive regulation of cellular metabolic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform chemical substances.
31326	regulation of cellular biosynthetic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances, carried out by individual cells.
31327	negative regulation of cellular biosynthetic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances, carried out by individual cells.
31328	positive regulation of cellular biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of substances, carried out by individual cells.
31329	regulation of cellular catabolic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells.
31330	negative regulation of cellular catabolic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells.
31331	positive regulation of cellular catabolic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells.
31332	RNAi effector complex	C	Any protein complex that mediates the effects of small interfering RNAs on gene expression. Most known examples contain one or more members of the Argonaute family of proteins.
31333	negative regulation of protein complex assembly	P	Any process that stops, prevents, or reduces the frequency, rate or extent of protein complex assembly.
31334	positive regulation of protein complex assembly	P	Any process that activates or increases the frequency, rate or extent of protein complex assembly.
31335	regulation of sulfur amino acid metabolic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving sulfur amino acids.
31336	negative regulation of sulfur amino acid metabolic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving sulfur amino acids.
31337	positive regulation of sulfur amino acid metabolic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving sulfur amino acids.
31338	regulation of vesicle fusion	P	Any process that modulates the frequency, rate or extent of vesicle fusion.
31339	negative regulation of vesicle fusion	P	Any process that stops, prevents, or reduces the frequency, rate or extent of vesicle fusion.
31340	positive regulation of vesicle fusion	P	Any process that activates or increases the frequency, rate or extent of vesicle fusion.
31341	regulation of cell killing	P	Any process that modulates the frequency, rate or extent of cell killing, the process in which a cell brings about the death of another cell, either in the same or a different organism.
31342	negative regulation of cell killing	P	Any process that stops, prevents, or reduces the frequency, rate or extent of cell killing.
31343	positive regulation of cell killing	P	Any process that activates or increases the frequency, rate or extent of cell killing.
31344	regulation of cell projection organization	P	Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell projections.
31345	negative regulation of cell projection organization	P	Any process that stops, prevents, or reduces the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell projections.
31346	positive regulation of cell projection organization	P	Any process that activates or increases the frequency, rate or extent of the process involved in the formation, arrangement of constituent parts, or disassembly of cell projections.
31347	regulation of defense response	P	Any process that modulates the frequency, rate or extent of a defense response.
31348	negative regulation of defense response	P	Any process that stops, prevents, or reduces the frequency, rate or extent of a defense response.
31349	positive regulation of defense response	P	Any process that activates or increases the frequency, rate or extent of a defense response.
31350	intrinsic component of plastid membrane	C	The component of the plastid membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.
31351	integral component of plastid membrane	C	The component of the plastid membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
31352	intrinsic component of plastid inner membrane	C	The component of the plastid inner membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.
31353	integral component of plastid inner membrane	C	The component of the plastid inner membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
31354	intrinsic component of plastid outer membrane	C	The component of the plastid outer membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.
31355	integral component of plastid outer membrane	C	The component of the plastid outer membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
31356	intrinsic component of chloroplast inner membrane	C	The component of the chloroplast inner membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.
31357	integral component of chloroplast inner membrane	C	The component of the chloroplast inner membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
31358	intrinsic component of chloroplast outer membrane	C	The component of the chloroplast outer membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.
31359	integral component of chloroplast outer membrane	C	The component of the chloroplast outer membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
31360	intrinsic component of thylakoid membrane	C	The component of the thylakoid membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.
31361	integral component of thylakoid membrane	C	The component of the thylakoid membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
31362	anchored component of external side of plasma membrane	C	The component of the plasma membrane consisting of the gene products that are tethered to the external side of the membrane only by a covalently attached anchor, such as a lipid group embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping.
31363	N-terminal protein amino acid deamination	P	The removal of an amino group from the N-terminal amino acid residue of a protein.
31364	N-terminal protein amino acid deamination, from side chain	P	The removal of an amino group from the side chain of an N-terminal asparagine or glutamine residue of a protein.
31365	N-terminal protein amino acid modification	P	The alteration of the N-terminal amino acid residue in a protein.
31366	N-terminal peptidyl-asparagine deamination	P	The removal of an amino group from the side chain of an N-terminal asparagine residue of a protein.
31367	N-terminal peptidyl-glutamine deamination	P	The removal of an amino group from the side chain of an N-terminal glutamine residue of a protein.
31369	translation initiation factor binding	F	Interacting selectively and non-covalently with a translation initiation factor, any polypeptide factor involved in the initiation of ribosome-mediated translation.
31370	eukaryotic initiation factor 4G binding	F	Interacting selectively and non-covalently with eukaryotic initiation factor 4G, a polypeptide factor involved in the initiation of ribosome-mediated translation.
31371	ubiquitin conjugating enzyme complex	C	Any complex that possesses ubiquitin conjugating enzyme activity.
31372	UBC13-MMS2 complex	C	A heterodimeric ubiquitin conjugating enzyme complex that catalyzes assembly of K63-linked polyubiquitin chains, which act as a signal to promote error-free DNA postreplication repair; in Saccharomyces the complex comprises Ubc13p and Mms2p.
31379	RNA-directed RNA polymerase complex	C	A protein complex that possesses RNA-directed RNA polymerase activity.
31380	nuclear RNA-directed RNA polymerase complex	C	A complex required for RNAi mediated heterochromatin assembly. In S. pombe this contains RNA-directed RNA polymerase, a putative helicase and a protein containing a pap25 associated domain.
31381	viral RNA-directed RNA polymerase complex	C	A virus-specific protein complex that possesses RNA-dependent RNA polymerase activity and replicates the genome of an RNA virus.
31382	mating projection assembly	P	The aggregation, arrangement and bonding together of a set of components to form a cell projection in response to mating pheromone. This process is observed in unicellular fungi.
31383	regulation of mating projection assembly	P	Any process that modulates the frequency, rate, or extent of mating projection formation by unicellular fungi.
31384	regulation of initiation of mating projection growth	P	Any process that modulates the frequency, rate, or extent of the start of mating projection formation by unicellular fungi.
31385	regulation of termination of mating projection growth	P	Any process that modulates the frequency, rate, or extent of the end of mating projection formation by unicellular fungi.
31386	protein tag	F	A molecular function exhibited by a protein that is covalently attached (AKA tagged or conjugated) to another protein where it acts as a marker, recognized by the cellular apparatus to target the tagged protein for some cellular process such as modification, sequestration, transport or degradation.
31387	MPF complex	C	A complex consisting of a Cdc2-class (also known as Cdc28) cyclin-dependent kinase and an M-phase cyclin such as S. pombe Cdc13. The MPF complex phosphorylates and activates the anaphase promoting complex (APC).
31388	organic acid phosphorylation	P	The process of introducing one or more phosphate groups into an organic acid.
31389	Rad17 RFC-like complex	C	A pentameric protein complex related to replication factor C, which loads a trimeric complex of checkpoint proteins (known as the checkpoint clamp or 9-1-1 complex) onto DNA at damage sites; functions in DNA damage cell cycle checkpoints. In Schizosaccharomyces pombe the subunits are known as Rad17, Rfc2, Rfc3, Rfc4, and Rfc5, while in Saccharomyces cerevisiae the subunits are known as Rad24p, Rfc2p, Rfc3p, Rfc4p, and Rfc5p.
31390	Ctf18 RFC-like complex	C	A heptameric complex related to replication factor C, which loads the DNA polymerase processivity factor proliferating cell nuclear antigen (PCNA) onto DNA and plays a vital role in chromosome cohesion. In Saccharomyces the subunits are known as Ctf18p, Rfc2p, Rfc3p, Rfc4p, Rfc5p, Dcc1p, and Ctf8p.
31391	Elg1 RFC-like complex	C	A pentameric replication factor C (RLC) complex, which unloads the DNA polymerase processivity factor proliferating cell nuclear antigen (PCNA) from chromatin and has roles in telomere length regulation and other aspects of genome stability. In Saccharomyces the subunits are known as Elg1p, Rfc2p, Rfc3p, Rfc4p, and Rfc5p.
31392	regulation of prostaglandin biosynthetic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of prostaglandin.
31393	negative regulation of prostaglandin biosynthetic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of prostaglandin.
31394	positive regulation of prostaglandin biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of prostaglandin.
31395	bursicon neuropeptide hormone complex	C	A neuropeptide hormone secreted by the central nervous system of insects that stimulates the tanning and sclerotization of the adult cuticle following eclosion. The active hormone consists of an obligate heterodimer of the alpha and beta subunits.
31396	regulation of protein ubiquitination	P	Any process that modulates the frequency, rate or extent of the addition of ubiquitin groups to a protein.
31397	negative regulation of protein ubiquitination	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the addition of ubiquitin groups to a protein.
31398	positive regulation of protein ubiquitination	P	Any process that activates or increases the frequency, rate or extent of the addition of ubiquitin groups to a protein.
31399	regulation of protein modification process	P	Any process that modulates the frequency, rate or extent of the covalent alteration of one or more amino acid residues within a protein.
31400	negative regulation of protein modification process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the covalent alteration of one or more amino acid residues within a protein.
31401	positive regulation of protein modification process	P	Any process that activates or increases the frequency, rate or extent of the covalent alteration of one or more amino acid residues within a protein.
31402	sodium ion binding	F	Interacting selectively and non-covalently with sodium ions (Na+).
31403	lithium ion binding	F	Interacting selectively and non-covalently with lithium ions (Li+).
31404	chloride ion binding	F	Interacting selectively and non-covalently with chloride ions (Cl-).
31405	lipoic acid binding	F	Interacting selectively and non-covalently with lipoic acid, 1,2-dithiolane-3-pentanoic acid.
31406	carboxylic acid binding	F	Interacting selectively and non-covalently with a carboxylic acid, any organic acid containing one or more carboxyl (COOH) groups or anions (COO-).
31407	oxylipin metabolic process	P	The chemical reactions and pathways involving any oxylipin, any of a group of biologically active compounds formed by oxidative metabolism of polyunsaturated fatty acids.
31408	oxylipin biosynthetic process	P	The chemical reactions and pathways resulting in the formation of any oxylipin, any of a group of biologically active compounds formed by oxidative metabolism of polyunsaturated fatty acids.
31409	pigment binding	F	Interacting selectively and non-covalently with a pigment, any general or particular coloring matter in living organisms, e.g. melanin.
31410	cytoplasmic vesicle	C	A vesicle found in the cytoplasm of a cell.
31411	gas vesicle	C	An intracellular non-membrane-bounded organelle; a hollow structure made of protein, which usually has the form of a cylindrical tube closed by conical end caps. By regulating their relative gas vesicle content, aquatic microbes are able to perform vertical migrations.
31412	gas vesicle organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a gas vesicle. A gas vesicle is a hollow structure made of protein, which usually has the form of a cylindrical tube closed by conical end caps.
31413	regulation of buoyancy	P	Any process that modulates an organism's tendency or ability to rise or float in a fluid medium such as water or air, often through the use of stored gases.
31414	N-terminal protein acetyltransferase complex	C	A complex that catalyzes the transfer of an acetyl group to the N-terminal residue of a protein acceptor molecule.
31415	NatA complex	C	A conserved complex that catalyzes the transfer of an acetyl group to an N-terminal Ser, Ala, Gly, or Thr residue of a protein acceptor molecule. In Saccharomyces the complex includes Nat1p and Ard1p, and may contain additional proteins.
31416	NatB complex	C	A conserved complex that catalyzes the transfer of an acetyl group to the N-terminal residue of a protein acceptor molecule that has a Met-Glu, Met-Asp, Met-Asn, or Met-Met N-terminus. In Saccharomyces the complex includes Nat3p and Mdm20p.
31417	NatC complex	C	A conserved complex that catalyzes the transfer of an acetyl group to the N-terminal residue of a protein acceptor molecule that has a Met-Ile, Met-Leu, Met-Trp, or Met-Phe N-terminus. In Saccharomyces the complex includes Mak3p, Mak10p, and Mak31p.
31418	L-ascorbic acid binding	F	Interacting selectively and non-covalently with L-ascorbic acid, (2R)-2-[(1S)-1,2-dihydroxyethyl]-4-hydroxy-5-oxo-2,5-dihydrofuran-3-olate; L-ascorbic acid is vitamin C and has co-factor and anti-oxidant activities in many species.
31419	cobalamin binding	F	Interacting selectively and non-covalently with cobalamin (vitamin B12), a water-soluble vitamin characterized by possession of a corrin nucleus containing a cobalt atom.
31420	alkali metal ion binding	F	Interacting selectively and non-covalently with any alkali metal ion; alkali metals are those elements in group Ia of the periodic table, with the exception of hydrogen.
31421	invertasome	C	A complex formed by a recombinase, a regulatory protein, and the DNA sequences bound by each protein; catalyzes a reversible site-specific recombination reaction that results in the alternate expression of one or more genes in various contexts.
31422	RecQ helicase-Topo III complex	C	A complex containing a RecQ family helicase and a topoisomerase III homologue; may also include one or more additional proteins; conserved from E. coli to human.
31423	hexon binding	F	Interacting selectively and non-covalently with a hexon, the major protein component of the icosahedral capsid of an adenovirus.
31424	keratinization	P	The process in which the cytoplasm of the outermost cells of the vertebrate epidermis is replaced by keratin. Keratinization occurs in the stratum corneum, feathers, hair, claws, nails, hooves, and horns.
31425	chloroplast RNA processing	P	The conversion of a primary RNA molecule transcribed from a chloroplast genome into one or more mature RNA molecules.
31426	polycistronic mRNA processing	P	The conversion of a primary mRNA transcript containing more than one complete protein-coding region into individual mature mRNA molecules.
31427	response to methotrexate	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methotrexate stimulus. Methotrexate is 4-amino-10-methylformic acid, a folic acid analogue that is a potent competitive inhibitor of dihydrofolate reductase.
31428	box C/D snoRNP complex	C	A ribonucleoprotein complex containing small nucleolar RNA of the box C/D type that can carry out ribose-2'-O-methylation of target RNAs.
31429	box H/ACA snoRNP complex	C	A box H/ACA RNP complex that is located in the nucleolus.
31430	M band	C	The midline of aligned thick filaments in a sarcomere; location of specific proteins that link thick filaments. Depending on muscle type the M band consists of different numbers of M lines.
31431	Dbf4-dependent protein kinase complex	C	A heterodimeric protein complex required for the activation of DNA replication origins; comprises a catalytic subunit and a regulatory subunit (in Saccharomyces, Cdc7p and Dbf4p, respectively); complexes identified in other species generally contain proteins related to the Saccharomyces proteins.
31432	titin binding	F	Interacting selectively and non-covalently with titin, any of a family of giant proteins found in striated and smooth muscle. In striated muscle, single titin molecules span half the sarcomere, with their N- and C-termini in the Z-disc and M-line, respectively.
31433	telethonin binding	F	Interacting selectively and non-covalently with telethonin, a protein found in the Z disc of striated muscle and which is a substrate of the titin kinase.
31434	mitogen-activated protein kinase kinase binding	F	Interacting selectively and non-covalently with a mitogen-activated protein kinase kinase, any protein that can phosphorylate a MAP kinase.
31435	mitogen-activated protein kinase kinase kinase binding	F	Interacting selectively and non-covalently with a mitogen-activated protein kinase kinase kinase, any protein that can phosphorylate a MAP kinase kinase.
31436	BRCA1-BARD1 complex	C	A heterodimeric complex comprising BRCA1 and BARD1, which possesses ubiquitin ligase activity and is involved in genome maintenance, possibly by functioning in surveillance for DNA damage.
31437	regulation of mRNA cleavage	P	Any process that modulates the frequency, rate or extent of mRNA cleavage, any process in which a pre-mRNA or mRNA molecule is cleaved at specific sites or in a regulated manner.
31438	negative regulation of mRNA cleavage	P	Any process that stops, prevents, or reduces the frequency, rate or extent of mRNA cleavage.
31439	positive regulation of mRNA cleavage	P	Any process that activates or increases the frequency, rate or extent of mRNA cleavage.
31440	regulation of mRNA 3'-end processing	P	Any process that modulates the frequency, rate or extent of mRNA 3'-end processing, any process involved in forming the mature 3' end of an mRNA molecule.
31441	negative regulation of mRNA 3'-end processing	P	Any process that stops, prevents, or reduces the frequency, rate or extent of mRNA 3'-end processing.
31442	positive regulation of mRNA 3'-end processing	P	Any process that activates or increases the frequency, rate or extent of mRNA 3'-end processing.
31443	fast-twitch skeletal muscle fiber contraction	P	A process in which force is generated within fast-twitch skeletal muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The fast-twitch skeletal muscle is characterized by fast time parameters, high force development and fatiguability.
31444	slow-twitch skeletal muscle fiber contraction	P	A process in which force is generated within slow-twitch skeletal muscle tissue, resulting in a change in muscle geometry. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The slow-twitch skeletal muscle is characterized by slow time parameters, low force development and resistance to fatigue.
31445	regulation of heterochromatin assembly	P	Any process that modulates the frequency, rate, extent or location of heterochromatin formation.
31446	regulation of fast-twitch skeletal muscle fiber contraction	P	Any process that modulates the frequency, rate or extent of fast-twitch skeletal muscle contraction.
31447	negative regulation of fast-twitch skeletal muscle fiber contraction	P	Any process that stops, prevents, or reduces the frequency, rate or extent of fast-twitch skeletal muscle contraction.
31448	positive regulation of fast-twitch skeletal muscle fiber contraction	P	Any process that activates or increases the frequency, rate or extent of fast-twitch skeletal muscle contraction.
31449	regulation of slow-twitch skeletal muscle fiber contraction	P	Any process that modulates the frequency, rate or extent of slow-twitch skeletal muscle contraction.
31450	negative regulation of slow-twitch skeletal muscle fiber contraction	P	Any process that stops, prevents, or reduces the frequency, rate or extent of slow-twitch skeletal muscle contraction.
31451	positive regulation of slow-twitch skeletal muscle fiber contraction	P	Any process that activates or increases the frequency, rate or extent of slow-twitch skeletal muscle contraction.
31452	negative regulation of heterochromatin assembly	P	Any process that stops, prevents, or reduces the frequency, rate or extent of heterochromatin formation.
31453	positive regulation of heterochromatin assembly	P	Any process that activates or increases the frequency, rate or extent of heterochromatin formation.
31454	regulation of extent of heterochromatin assembly	P	Any process that modulates the extent or location of heterochromatin formation.
31455	glycine betaine metabolic process	P	The chemical reactions and pathways involving glycine betaine, N-trimethylglycine.
31456	glycine betaine biosynthetic process	P	The chemical reactions and pathways resulting in the formation of glycine betaine, N-trimethylglycine.
31457	glycine betaine catabolic process	P	The chemical reactions and pathways resulting in the breakdown of glycine betaine, N-trimethylglycine.
31458	betaine-transporting ATPase activity	F	Catalysis of the reaction: ATP + H2O + a betaine(out) = ADP + phosphate + a betaine(in).
31459	glycine betaine-transporting ATPase activity	F	Catalysis of the reaction: ATP + H2O + glycine betaine(out) = ADP + phosphate + glycine betaine(in).
31460	glycine betaine transport	P	The directed movement of glycine betaine, N-trimethylglycine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
31461	cullin-RING ubiquitin ligase complex	C	Any ubiquitin ligase complex in which the catalytic core consists of a member of the cullin family and a RING domain protein; the core is associated with one or more additional proteins that confer substrate specificity.
31462	Cul2-RING ubiquitin ligase complex	C	A ubiquitin ligase complex in which a cullin from the Cul2 subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by an elongin-BC adaptor and a SOCS/BC box protein.
31463	Cul3-RING ubiquitin ligase complex	C	A ubiquitin ligase complex in which a cullin from the Cul3 subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by a BTB-domain-containing protein.
31464	Cul4A-RING E3 ubiquitin ligase complex	C	A ubiquitin ligase complex in which a cullin from the Cul4A subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by an adaptor protein.
31465	Cul4B-RING E3 ubiquitin ligase complex	C	A ubiquitin ligase complex in which a cullin from the Cul4B subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by unknown subunits.
31466	Cul5-RING ubiquitin ligase complex	C	A ubiquitin ligase complex in which a cullin from the Cul5 subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by an elongin-BC adaptor and a SOCS/BC box protein.
31467	Cul7-RING ubiquitin ligase complex	C	A ubiquitin ligase complex in which a cullin from the Cul7 subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by a Skp1 linker and an F-box protein.
31468	nuclear envelope reassembly	P	The reformation of the nuclear envelope following its breakdown in the context of a normal process.
31469	polyhedral organelle	C	An organelle found in bacteria consisting of a proteinaceous coat containing metabolic enzymes whose purpose is the sequestration or concentration of metabolites and which has the appearance of a polygonal granule by electron microscopy.
31470	carboxysome	C	An organelle consisting of a proteinaceous coat and enzymes for the fixation of carbon dioxide including mechanisms for the concentration of carbonate to increase the efficiency of fixation under low-carbon dioxide conditions.
31471	ethanolamine degradation polyhedral organelle	C	An organelle found in bacteria consisting of a proteinaceous coat containing enzymes for the degradation of ethanolamine whose purpose is the protection of the rest of the cell from the toxic acetaldehyde product of the enzyme ethanolamine ammonia lyase.
31472	propanediol degradation polyhedral organelle	C	An organelle found in bacteria consisting of a proteinaceous coat containing enzymes for the degradation of 1,2-propanediol whose purpose is the protection of the rest of the cell from the toxic propionaldehyde product of the enzyme diol dehydratase.
31473	myosin III binding	F	Interacting selectively and non-covalently with a class III myosin; myosin III is monomeric and has an N terminal kinase domain.
31474	myosin IV complex	C	A myosin complex containing one or more class IV myosin heavy chains and associated light chains; myosin IV is relatively uncharacterized, but is predicted to have a single motor domain, one IQ motif and a tail with a Myosin Tail Homology (myTH4) domain homologous to that in the tails of myosins VII and XV.
31475	myosin V complex	C	A myosin complex containing a dimer of class V myosin heavy chains and associated light chains; involved in intracellular transport. Myosin V is a dimeric molecule consisting of conserved motor domains followed by 6 IQ motifs which bind specific light chains and calmodulin. The tail domain is important for cellular localization and cargo binding and can be divided into an alpha-helical coiled coil region and a C-terminal globular region.
31476	myosin VI complex	C	A myosin complex containing one or more class VI myosin heavy chains and associated light chains. Myosin VI has a single IQ motif in the neck and a tail region with a coiled coil domain followed by a unique globular domain; a unique insertion that enables myosin VI to move towards the pointed or minus end of actin filaments.
31477	myosin VII complex	C	A myosin complex containing a dimer of class VII myosin heavy chains and associated light chains. Myosin VII (240 kDa) is predicted to be a dimeric molecule with 5 IQ motifs and a tail region with a short stretch of coiled coil followed by two myosin-tail homology (MyTH4) domains, two talin-binding (FERM) domains and an SH3-domain.
31478	myosin VIII complex	C	A myosin complex containing a dimer of class VIII myosin heavy chains and associated light chains. Myosin VIII is predicted to be dimeric, and contain an unusual 100-190 residue N-terminal extension prior to their motor domains, 3-4 IQ motifs, a short region (~70 residues) of predicted alpha-helical coiled coil and a C-terminal domain.
31479	myosin IX complex	C	A myosin complex containing a class IX myosin heavy chain and associated light chains. Myosin IX is monomeric with a motor domain containing an N-terminal extension and an insert in the actin binding interface, followed by four to six IQ motifs and a tail region that contains a zinc binding motif and a domain with homology to GTPase activating proteins (GAPs) of the Rho family of G-proteins.
31480	myosin X complex	C	A myosin complex containing one or more class X myosin heavy chains and associated light chains.
31481	myosin XI complex	C	A myosin complex containing a dimer of class XI myosin heavy chains and associated light chains. Myosin XI heavy chain sizes are similar in molecular structure to the class V myosins with 5 to 6 IQ motifs and tail regions with predicted coiled coil domains (forming dimeric molecules) and large C-terminal regions.
31482	myosin XII complex	C	A myosin complex containing one or more class XII myosin heavy chains and associated light chains; myosin XII contains a large tail region with two MyTH4 domains and a short region of coiled coil.
31483	myosin XIII complex	C	A myosin complex containing one or more class XIII myosin heavy chains and associated light chains.
31484	myosin XIV complex	C	A myosin complex containing a class XIV myosin heavy chain and associated light chains; myosin XIV heavy chains are the simplest known, containing a motor domain, no classic IQ motif and variable length tails.
31485	myosin XV complex	C	A myosin complex containing a class XV myosin heavy chain and associated light chains. Myosin XV is single headed, and has a large extension (1200aa) at the N-terminus of the motor domain, two IQ motifs and a tail with a similar domain structure to that of the tail of myosin VII.
31486	myosin XVI complex	C	A myosin complex containing a class XVI myosin heavy chains and associated light chains; myosin XVI heavy chains contain ankyrin repeat.
31487	myosin XVII complex	C	A myosin complex containing one or more class XVII myosin heavy chains and associated light chains.
31488	myosin XVIII complex	C	A myosin complex containing a class XVIII myosin heavy chain and associated light chains; myosin XVIII heavy chains contain an N-terminal PDZ domain.
31489	myosin V binding	F	Interacting selectively and non-covalently with a class V myosin; myosin V is a dimeric molecule involved in intracellular transport.
31490	chromatin DNA binding	F	Interacting selectively and non-covalently with DNA that is assembled into chromatin.
31491	nucleosome binding	F	Interacting selectively and non-covalently with a nucleosome, a complex comprised of DNA wound around a multisubunit core and associated proteins, which forms the primary packing unit of DNA into higher order structures.
31492	nucleosomal DNA binding	F	Interacting selectively and non-covalently with the DNA portion of a nucleosome.
31493	nucleosomal histone binding	F	Interacting selectively and non-covalently with a histone that is assembled into a nucleosome.
31494	regulation of mating type switching	P	Any process that modulates the frequency, rate or extent of mating type switching, the conversion of a single-cell organism from one mating type to another by the precise replacement of a DNA sequence at the expressed mating type locus with a copy of a sequence from a donor locus.
31495	negative regulation of mating type switching	P	Any process that stops, prevents, or reduces the frequency, rate or extent of mating type switching.
31496	positive regulation of mating type switching	P	Any process that activates or increases the frequency, rate or extent of mating type switching.
31497	chromatin assembly	P	The assembly of DNA, histone proteins, other associated proteins, and sometimes RNA, into chromatin structure, beginning with the formation of the basic unit, the nucleosome, followed by organization of the nucleosomes into higher order structures, ultimately giving rise to a complex organization of specific domains within the nucleus.
31498	chromatin disassembly	P	The controlled breakdown of chromatin from a higher order structure into its simpler subcomponents, DNA, histones, other proteins, and sometimes RNA.
31499	TRAMP complex	C	A multiprotein complex having distributive polyadenylation activity of a variety of RNA substrates including hypomodified and incorrectly folded tRNAs, pre-snRNAs, pre-snoRNAs, incorrectly spliced or processed pre-mRNAs, cryptic unstable transcripts (CUTs), pre-rRNAs and rRNA fragments released as part of rRNA processing. In S. cerevisiae, the complex consists of either Pap2 (also known as Trf4) or Trf5, Air1 or Air2, and Mtr4, and is involved in RNA 3'-end processing and in RNA surveillance and quality control.
31500	Tea1 cell-end complex	C	A high molecular weight complex characterized in S. pombe containing the cell-end anchoring protein Tea1. This complex is transported to the cell ends by microtubules and is involved in bipolar growth and the maintennce of normal cell polarity.
31501	mannosyltransferase complex	C	A complex that posseses mannosyltransferase activity.
31502	dolichyl-phosphate-mannose-protein mannosyltransferase complex	C	A complex that possesses dolichyl-phosphate-mannose-protein mannosyltransferase activity; usually includes members of the PMT1 and PMT2 protein subfamilies.
31503	protein complex localization	P	A localization process that acts on a protein complex; the complex is transported to, or maintained in, a specific location.
31504	peptidoglycan-based cell wall organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the peptidoglycan-based cell wall.
31505	fungal-type cell wall organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the fungal-type cell wall.
31506	cell wall glycoprotein biosynthetic process	P	The chemical reactions and pathways resulting in the formation of cell wall glycoproteins, any cell wall protein that contains covalently bound sugar residues.
31507	heterochromatin assembly	P	The assembly of chromatin into heterochromatin, a compact and highly condensed form that is often, but not always, transcriptionally silent.
31508	pericentric heterochromatin assembly	P	The assembly of chromatin into heterochromatin that is located adjacent to the CENP-A rich centromere 'central core' and characterized by the modified histone H3K9me3.
31509	telomeric heterochromatin assembly	P	The assembly of chromatin into heterochromatin at the telomere.
31510	SUMO activating enzyme complex	C	A conserved heterodimeric complex with SUMO activating enzyme activity.
31511	Mis6-Sim4 complex	C	A protein complex that forms part of the inner centromere, which is involved in the loading of the centromeric histone h3 variant CENP-A onto centromeres and in centromere specific heterochromatin formation. The complex contains about 12 proteins, of which two are known as Mis6 and Sim4 in S. pombe and CENP-I and CENP-H in human.
31514	motile cilium	C	A cilium which may have a variable arrangement of axonemal microtubules and also contains molecular motors. It may beat with a whip-like pattern that promotes cell motility or transport of fluids and other cells across a cell surface, such as on epithelial cells that line the lumenal ducts of various tissues; or they may display a distinct twirling motion that directs fluid flow asymmetrically across the cellular surface to affect asymmetric body plan organization. Motile cilia can be found in single as well as multiple copies per cell.
31515	tRNA (m1A) methyltransferase complex	C	A protein complex involved in the catalysis of the formation of the modified nucleotide 1-methyladenosine (m1A) in tRNA. In yeast, it is a heterotetramer of two subunits, Gcd10p and Gcd14p, while in bacteria and archaea it is a homotetramer.
31516	far-red light photoreceptor activity	F	The function of absorbing and responding to electromagnetic radiation with a wavelength of approximately 730nm. The response may involve a change in conformation.
31517	red light photoreceptor activity	F	The function of absorbing and responding to electromagnetic radiation with a wavelength of approximately 660nm. The response may involve a change in conformation.
31518	CBF3 complex	C	A multisubunit protein complex that binds to centromeric DNA and initiates kinetochore assembly. In yeast, this complex consists of four subunits, namely Ctf13p, Skp1p, Cep3p and Cbf2p.
31519	PcG protein complex	C	A chromatin-associated multiprotein complex containing Polycomb Group proteins. In Drosophila, Polycomb group proteins are involved in the long-term maintenance of gene repression, and PcG protein complexes associate with Polycomb group response elements (PREs) in target genes to regulate higher-order chromatin structure.
31520	plasma membrane of cell tip	C	The portion of the plasma membrane surrounding the cell tip.
31521	spitzenkorper	C	Structure within the hyphal tip of filamentous fungi that acts as an organizing center for hyphal tip growth; may function to supply vesicles to the elongating tip and/or to organize cytoskeletal microfilaments.
31522	cell envelope Sec protein transport complex	C	A transmembrane protein complex involved in the translocation of proteins across the cytoplasmic membrane. In Gram-negative bacteria, Sec-translocated proteins are subsequently secreted via the type II, IV, or V secretion systems. Sec complex components include SecA, D, E, F, G, Y and YajC.
31523	Myb complex	C	A multisubunit complex consisting of Myb and other proteins that regulates site specific DNA replication, gene amplification and transcriptional repression.
31524	menthol metabolic process	P	The chemical reactions and pathways involving menthol, the monoterpene 2-isopropyl-5-methylcyclohexanol.
31525	menthol biosynthetic process	P	The chemical reactions and pathways resulting in the formation of menthol, the monoterpene 2-isopropyl-5-methylcyclohexanol.
31526	brush border membrane	C	The portion of the plasma membrane surrounding the brush border.
31527	filopodium membrane	C	The portion of the plasma membrane surrounding a filopodium.
31528	microvillus membrane	C	The portion of the plasma membrane surrounding a microvillus.
31529	ruffle organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a ruffle, a projection at the leading edge of a crawling cell.
31530	gonadotropin-releasing hormone receptor binding	F	Interacting selectively and non-covalently with a receptor for gonadotropin-releasing hormone (GnRH), a peptide hormone that is synthesized and released by the hypothalamus and is responsible for the release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) from the anterior pituitary.
31531	thyrotropin-releasing hormone receptor binding	F	Interacting selectively and non-covalently with a receptor for thyrotropin-releasing hormone, a tripeptide hormone that is produced by the hypothalamus and stimulates the release of thyroid-stimulating hormone (TSH) and prolactin by the anterior pituitary.
31532	actin cytoskeleton reorganization	P	A process that is carried out at the cellular level which results in dynamic structural changes to the arrangement of constituent parts of cytoskeletal structures comprising actin filaments and their associated proteins.
31533	mRNA cap methyltransferase complex	C	A protein complex that consists of an RNA 5' triphosphatase and a guanyl transferase (Cet1p and Ceg1p in S. cerevisiae; Pct1 and Ceg1 in S. pombe) and is involved in mRNA capping.
31534	minus-end directed microtubule sliding	P	The movement of one microtubule along another microtubule, where the motion is directed towards the minus ends of the microtubules.
31535	plus-end directed microtubule sliding	P	The movement of one microtubule along another microtubule, where the motion is directed towards the plus ends of the microtubules.
31536	positive regulation of exit from mitosis	P	Any process that activates or increases the rate of progression from anaphase/telophase (high mitotic CDK activity) to G1 (low mitotic CDK activity).
31537	regulation of anthocyanin metabolic process	P	Any process that modulates the frequency, rate or extent of chemical reactions and pathways involving anthocyanins.
31538	negative regulation of anthocyanin metabolic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of chemical reactions and pathways involving anthocyanins.
31539	positive regulation of anthocyanin metabolic process	P	Any process that activates or increases the frequency, rate or extent of chemical reactions and pathways involving anthocyanins.
31540	regulation of anthocyanin biosynthetic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of anthocyanins.
31541	negative regulation of anthocyanin biosynthetic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of anthocyanins.
31542	positive regulation of anthocyanin biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of anthocyanins.
31543	peptidyl-proline dioxygenase activity	F	Catalysis of the reaction: peptidyl L-proline + 2-oxoglutarate + O2 = peptidyl hydroxy-L-proline + succinate + CO2.
31544	peptidyl-proline 3-dioxygenase activity	F	Catalysis of the reaction: peptidyl L-proline + 2-oxoglutarate + O2 = peptidyl trans-3-hydroxy-L-proline + succinate + CO2.
31545	peptidyl-proline 4-dioxygenase activity	F	Catalysis of the reaction: peptidyl L-proline + 2-oxoglutarate + O2 = peptidyl trans-4-hydroxy-L-proline + succinate + CO2.
31546	brain-derived neurotrophic factor receptor binding	F	Interacting selectively and non-covalently with the brain-derived neurotrophic factor receptor.
31547	brain-derived neurotrophic factor receptor signaling pathway	P	The series of molecular signals generated as a consequence of a brain-derived neurotrophic factor receptor binding to one of its physiological ligands.
31548	regulation of brain-derived neurotrophic factor receptor signaling pathway	P	Any process that modulates the frequency, rate or extent of signaling via the brain-derived neurotrophic factor receptor signaling pathway.
31549	negative regulation of brain-derived neurotrophic factor receptor signaling pathway	P	Any process that stops, prevents, or reduces the frequency, rate or extent of signaling via the brain-derived neurotrophic factor receptor signaling pathway.
31550	positive regulation of brain-derived neurotrophic factor receptor signaling pathway	P	Any process that activates or increases the frequency, rate or extent of signaling via the brain-derived neurotrophic factor receptor signaling pathway.
31551	regulation of brain-derived neurotrophic factor-activated receptor activity	P	Any process that modulates the frequency, rate or extent of brain-derived neurotrophic factor-activated receptor activity.
31552	negative regulation of brain-derived neurotrophic factor-activated receptor activity	P	Any process that stops, prevents, or reduces the frequency, rate or extent of brain-derived neurotrophic factor-activated receptor activity.
31553	positive regulation of brain-derived neurotrophic factor-activated receptor activity	P	Any process that activates or increases the frequency, rate or extent of brain-derived neurotrophic factor-activated receptor activity.
31554	regulation of DNA-templated transcription, termination	P	Any process that modulates the frequency, rate, extent, or location of DNA-templated transcription termination, the process in which transcription is completed; the formation of phosphodiester bonds ceases, the RNA-DNA hybrid dissociates, and RNA polymerase releases the DNA.
31555	transcriptional attenuation	P	Regulation of transcription through variation in where transcription termination occurs.
31556	transcriptional attenuation by ribosome	P	A type of transcriptional regulation at the level of early termination. This process can occur only in prokaryotes, where transcription of an operon into messenger RNA and translation of that mRNA into polypeptides occur simultaneously. The general principle is that alternative mRNA secondary structures occur under different physiological conditions such as available amount of a particular amino acid. One set of conditions favors early termination of transcription. In the classic example of the trp biosynthesis operon, translation of the gene for a short, trp-containing polypeptide called the trp operon leader peptide pauses either at a trp codon (if tryptophan is scarce) or the stop codon (if trp is readily available). In the former situation transcription continues, but in the latter a Rho-independent terminator forms and reduces, or attenuates, expression of the tryptophan biosynthesis genes. Although the polypeptides encoded by leader peptide genes appear not to be stable once their translation is complete, it is suggested by recent studies that their nascent polypeptide chains interact specifically with ribosomes, specific uncharged tRNAs, or other cellular components to inhibit release at the stop codon and improve the function of transcriptional attenuation as a regulatory switch.
31559	oxidosqualene cyclase activity	F	Catalysis of the cyclization of (S)-2,3-epoxysqualene to form a triterpene.
31560	cellular bud neck polarisome	C	Protein complex that has a role in determining cell polarity, found at the neck of a fungal bud before and during cytokinesis.
31561	cellular bud tip polarisome	C	Protein complex that has a role in determining cell polarity, found at the tip of a growing fungal bud.
31562	hyphal tip polarisome	C	Protein complex that has a role in determining cell polarity, found at the tip of a growing fungal hypha.
31563	mating projection tip polarisome	C	Protein complex that has a role in determining cell polarity, found at the tip of the mating projection in unicellular fungi exposed to mating pheromone.
31564	transcription antitermination	P	Regulation of transcription by a mechanism that allows RNA polymerase to continue transcription beyond a termination site.
31566	actomyosin contractile ring maintenance	P	The cell cycle process in which the contractile ring is maintained in response to the cytokinesis checkpoint; that is when cytokinesis is delayed awaiting completion of nuclear division or the correct formation of cytokinetic structures. This process occurs in the context of cytokinesis that takes place as part of a cell cycle.
31567	mitotic cell size control checkpoint	P	The mitotic cell cycle checkpoint that delays or arrests cell cycle progression until cells have reached a critical size.
31568	G1 cell size control checkpoint	P	A mitotic cell cycle checkpoint that monitors cell size, and negatively regulates cell cycle progression between G1 and S phase until a critical size is reached.
31569	G2 cell size control checkpoint	P	A cell cycle checkpoint that monitors cell size, and negatively regulates cell cycle progression between G2 and M phase until a critical size is reached.
31570	DNA integrity checkpoint	P	A cell cycle process that controls cell cycle progression in response to changes in DNA structure by monitoring the integrity of the DNA. The DNA integrity checkpoint begins with detection of DNA damage, defects in DNA structure or DNA replication, and progresses through signal transduction and ends with cell cycle effector processes.
31571	mitotic G1 DNA damage checkpoint	P	A mitotic cell cycle checkpoint that detects and negatively regulates progression through the G1/S transition of the cell cycle in response to DNA damage.
31572	G2 DNA damage checkpoint	P	A cell cycle checkpoint that detects and negatively regulates progression from G2 to M phase in the cell cycle in response to DNA damage.
31573	intra-S DNA damage checkpoint	P	A mitotic cell cycle checkpoint that slows DNA synthesis in response to DNA damage by the prevention of new origin firing and the stabilization of slow replication fork progression.
31577	spindle checkpoint	P	A cell cycle checkpoint that originates from the mitotic or meiotic spindle.
31578	mitotic spindle orientation checkpoint	P	A cell cycle checkpoint that monitors and signals errors in the placement or orientation of the spindle in the cell. This delays the completion of anaphase until errors are corrected.
31579	membrane raft organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of membrane rafts, small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes.
31580	membrane raft distribution	P	The process that establishes the spatial arrangement of membrane rafts within a cellular membrane.
31581	hemidesmosome assembly	P	Assembly of hemidesmosomes, integrin-containing protein complexes that bind to laminin in the basal lamina. Hemidesmosomes form the contact between the basal surface of epithelial cells and the underlying basal lamina.
31582	replication fork arrest at rDNA repeats	P	A process that impedes the progress of the DNA replication fork at natural replication fork pausing sites within the eukaryotic rDNA repeat spacer.
31583	phospholipase D-activating G-protein coupled receptor signaling pathway	P	The series of molecular signals generated as a consequence of a G-protein coupled receptor binding to its physiological ligand, where the pathway proceeds with activation of phospholipase D (PLD) and a subsequent increase in cellular levels of phosphatidic acid (PA).
31584	activation of phospholipase D activity	P	Any process that initiates the activity of inactive phospholipase D.
31585	regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity	P	Any process that modulates the frequency, rate or extent of the activity of the inositol 1,4,5-trisphosphate-sensitive calcium-release channel.
31586	negative regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of the inositol 1,4,5-trisphosphate-sensitive calcium-release channel.
31587	positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity	P	Any process that activates or increases the frequency, rate or extent of the activity of the inositol 1,4,5-trisphosphate-sensitive calcium-release channel.
31588	nucleotide-activated protein kinase complex	C	A protein complex that possesses nucleotide-dependent protein kinase activity. The nucleotide can be AMP (in S. pombe and human) or ADP (in S. cerevisiae).
31589	cell-substrate adhesion	P	The attachment of a cell to the underlying substrate via adhesion molecules.
31590	wybutosine metabolic process	P	The chemical reactions and pathways involving wybutosine, 3H-imidazo[1,2-alpha]purine-7-butanoic acid, 4,9-dihydro- alpha-[(methoxycarbonyl)amino]- 4,6-dimethyl-9-oxo- 3-beta-D-ribofuranosyl methyl ester, a modified nucleoside found in some tRNA molecules.
31591	wybutosine biosynthetic process	P	The chemical reactions and pathways resulting in the formation of wybutosine, 3H-imidazo[1,2-alpha]purine-7-butanoic acid, 4,9-dihydro- alpha-[(methoxycarbonyl)amino]- 4,6-dimethyl-9-oxo- 3-beta-D-ribofuranosyl methyl ester, a modified nucleoside found in some tRNA molecules.
31592	centrosomal corona	C	An amorphous structure surrounding the core of the centrosome, from which microtubules are nucleated; contains gamma-tubulin.
31593	polyubiquitin binding	F	Interacting selectively and non-covalently with a polymer of ubiqutin.
31594	neuromuscular junction	C	The junction between the axon of a motor neuron and a muscle fiber. In response to the arrival of action potentials, the presynaptic button releases molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane of the muscle fiber, leading to a change in post-synaptic potential.
31595	nuclear proteasome complex	C	A proteasome found in the nucleus of a cell.
31597	cytosolic proteasome complex	C	A proteasome complex found in the cytosol of a cell.
31598	nuclear proteasome regulatory particle	C	The regulatory subcomplex of a proteasome located in the nucleus of a cell.
31600	cytosolic proteasome regulatory particle	C	A multisubunit complex located in the cytosol of a cell, which caps one or both ends of the proteasome core complex. This complex recognizes, unfolds ubiquitinated proteins and translocates them to the proteasome core complex.
31601	nuclear proteasome core complex	C	The core complex of a proteasome located in the nucleus of a cell.
31603	cytosolic proteasome core complex	C	The core complex of a proteasome located in the cytosol of a cell.
31604	nuclear proteasome core complex, alpha-subunit complex	C	The subunits forming the outer ring of the core complex of a proteasome located in the nucleus of a cell.
31606	cytosolic proteasome core complex, alpha-subunit complex	C	The proteasome core subcomplex that constitutes the two outer rings of the cytosolic proteasome core complex.
31607	nuclear proteasome core complex, beta-subunit complex	C	The subunits forming the inner ring of the core complex of a proteasome located in the nucleus of a cell.
31609	cytosolic proteasome core complex, beta-subunit complex	C	The proteasome core subcomplex that constitutes the two inner rings of the cytosolic proteasome core complex.
31610	nuclear proteasome regulatory particle, base subcomplex	C	The subunits of the regulatory particle that directly associate with the core complex of a proteasome located in the nucleus of a cell.
31612	cytosolic proteasome regulatory particle, base subcomplex	C	The subcomplex of the proteasome regulatory particle that directly associates with the proteasome core complex located in the cytosol of the cell.
31613	nuclear proteasome regulatory particle, lid subcomplex	C	The subunits that form the peripheral lid of the regulatory particle of a proteasome located in the nucleus of a cell.
31615	cytosolic proteasome regulatory particle, lid subcomplex	C	The subcomplex of the cytosolic proteasome regulatory particle that forms the peripheral lid, which is added on top of the base subcomplex.
31616	spindle pole centrosome	C	A centrosome from which one pole of a mitotic or meiotic spindle is organized.
31617	NMS complex	C	A supercomplex formed by the association of two subcomplexes (known as MIND and Ndc80 in Schizosaccharomyces) with additional proteins at the kinetochores of condensed nuclear chromosomes.
31618	nuclear pericentric heterochromatin	C	Nuclear heterochromatin that is located adjacent to the CENP-A rich centromere 'central core' and characterized by the modified histone H3K9me3.
31619	homologous chromosome orientation involved in meiotic metaphase I plate congression	P	The cell cycle process in which the sister centromeres of one chromosome attach to microtubules that emanate from the same spindle pole, which ensures that homologous maternal and paternal chromosomes are pulled in opposite directions at anaphase of meiosis I.
31620	regulation of fever generation	P	Any process that modulates the rate or extent of fever generation.
31621	negative regulation of fever generation	P	Any process that stops, prevents, or reduces the rate or extent of fever generation.
31622	positive regulation of fever generation	P	Any process that activates or increases the frequency, rate, or extent of fever generation.
31623	receptor internalization	P	A receptor-mediated endocytosis process that results in the movement of receptors from the plasma membrane to the inside of the cell. The process begins when cell surface receptors are monoubiquitinated following ligand-induced activation. Receptors are subsequently taken up into endocytic vesicles from where they are either targeted to the lysosome or vacuole for degradation or recycled back to the plasma membrane.
31624	ubiquitin conjugating enzyme binding	F	Interacting selectively and non-covalently with a ubiquitin conjugating enzyme, any of the E2 proteins.
31625	ubiquitin protein ligase binding	F	Interacting selectively and non-covalently with a ubiquitin protein ligase enzyme, any of the E3 proteins.
31626	beta-endorphin binding	F	Interacting selectively and non-covalently with beta-endorphin, a peptide generated by the cleavage of pro-opiomelanocortin.
31627	telomeric loop formation	P	The process in which linear telomeric DNA is remodeled into duplex loops, by the invasion of a 3' single-stranded overhang into the duplex region.
31628	opioid receptor binding	F	Interacting selectively and non-covalently with an opioid receptor.
31629	synaptic vesicle fusion to presynaptic active zone membrane	P	Fusion of the membrane of a synaptic vesicle with the presynaptic active zone membrane, thereby releasing its cargo neurotransmitters into the synaptic cleft.
31630	regulation of synaptic vesicle fusion to presynaptic membrane	P	Any process that modulates the frequency, rate or extent of synaptic vesicle fusion to the presynaptic membrane.
31631	negative regulation of synaptic vesicle fusion to presynaptic membrane	P	Any process that stops, prevents, or reduces the frequency, rate or extent of synaptic vesicle fusion to the presynaptic membrane.
31632	positive regulation of synaptic vesicle fusion to presynaptic membrane	P	Any process that activates or increases the frequency, rate or extent of synaptic vesicle fusion to the presynaptic membrane.
31633	xanthophore	C	A chromatophore containing yellow pigment.
31634	replication fork barrier binding	F	Interacting selectively and non-covalently with replication fork barriers, sites that inhibit the progress of replication forks.
31635	adenylate cyclase-inhibiting opioid receptor signaling pathway	P	The series of molecular signals generated as a consequence of an opioid receptor binding to its physiological ligand, where the pathway proceeds with inhibition of adenylyl cyclase and a subsequent decrease in the concentration of cyclic AMP (cAMP).
31637	regulation of neuronal synaptic plasticity in response to neurotrophin	P	The process in which a neurotrophic factor induces neuronal synaptic plasticity, the ability of neuronal synapses to change as circumstances require. They may alter function, such as increasing or decreasing their sensitivity, or they may increase or decrease in actual numbers.
31638	zymogen activation	P	The proteolytic processing of an inactive enzyme to an active form.
31639	plasminogen activation	P	The process in which inactive plasminogen is processed to active plasmin. This process includes cleavage at an internal Arg-Val site to form an N-terminal A-chain and C-terminal B-chain held together by a disulfide bond, and can include further proteolytic cleavage events to remove the preactivation peptide.
31640	killing of cells of other organism	P	Any process in an organism that results in the killing of cells of another organism, including in some cases the death of the other organism. Killing here refers to the induction of death in one cell by another cell, not cell-autonomous death due to internal or other environmental conditions.
31641	regulation of myelination	P	Any process that modulates the frequency, rate or extent of the formation of a myelin sheath around nerve axons.
31642	negative regulation of myelination	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the formation of a myelin sheath around nerve axons.
31643	positive regulation of myelination	P	Any process that activates or increases the frequency, rate or extent of the formation of a myelin sheath around nerve axons.
31644	regulation of neurological system process	P	Any process that modulates the frequency, rate or extent of a neurophysiological process, an organ system process carried out by any of the organs or tissues of neurological system.
31645	negative regulation of neurological system process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of a neurophysiological process.
31646	positive regulation of neurological system process	P	Any process that activates or increases the frequency, rate or extent of a neurophysiological process.
31647	regulation of protein stability	P	Any process that affects the structure and integrity of a protein, altering the likelihood of its degradation or aggregation.
31648	protein destabilization	P	Any process that decreases the stability of a protein, making it more vulnerable to degradative processes or aggregation.
31649	heat generation	P	Any homeostatic process in which an organism produces heat, thereby raising its internal temperature.
31650	regulation of heat generation	P	Any process that modulates the rate or extent of heat generation.
31651	negative regulation of heat generation	P	Any process that stops, prevents, or reduces the rate or extent of heat generation.
31652	positive regulation of heat generation	P	Any process that activates or increases the rate or extent of heat generation.
31653	heat dissipation	P	Any homeostatic process in which an organism releases excess heat to the environment, thereby lowering its internal temperature.
31654	regulation of heat dissipation	P	Any process that modulates the rate or extent of heat dissipation.
31655	negative regulation of heat dissipation	P	Any process that stops, prevents, or reduces the rate or extent of heat dissipation.
31656	positive regulation of heat dissipation	P	Any process that activates or increases the rate or extent of heat dissipation.
31657	regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle	P	Any process that controls the frequency, rate or extent of G1 cyclin-dependent protein serine/threonine kinase activity contributing to the G1/S transition of the cell cycle.
31658	negative regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle	P	Any process that stops, prevents, or reduces the frequency, rate or extent of cyclin-dependent protein serine/threonine kinase activity contributing to the G1/S transition of the cell cycle.
31659	positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle	P	Any process that activates or increases the frequency, rate or extent of cyclin-dependent protein serine/threonine kinase activity contributing to the G1/S transition of the cell cycle.
31660	regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle	P	Any process that modulates the frequency, rate or extent of cyclin-dependent protein serine/threonine kinase activity contributing to the G2/M transition of the cell cycle.
31661	negative regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle	P	Any process that stops, prevents, or reduces the frequency, rate or extent of cyclin-dependent protein serine/threonine kinase activity contributing to the G2/M transition of the cell cycle.
31662	positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle	P	Any process that activates or increases the frequency, rate or extent of cyclin-dependent protein serine/threonine kinase activity involved in the G2/M transition of the cell cycle.
31663	lipopolysaccharide-mediated signaling pathway	P	A series of molecular signals initiated by the binding of a lipopolysaccharide (LPS) to a receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription. Lipopolysaccharides are major components of the outer membrane of Gram-negative bacteria, making them prime targets for recognition by the immune system.
31664	regulation of lipopolysaccharide-mediated signaling pathway	P	Any process that modulates the frequency, rate or extent of signaling in response to detection of lipopolysaccharide.
31665	negative regulation of lipopolysaccharide-mediated signaling pathway	P	Any process that stops, prevents, or reduces the frequency, rate or extent of signaling in response to detection of lipopolysaccharide.
31666	positive regulation of lipopolysaccharide-mediated signaling pathway	P	Any process that activates or increases the frequency, rate or extent of signaling in response to detection of lipopolysaccharide.
31667	response to nutrient levels	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of nutrients.
31668	cellular response to extracellular stimulus	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an extracellular stimulus.
31669	cellular response to nutrient levels	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of nutrients.
31670	cellular response to nutrient	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nutrient stimulus.
31671	primary cell septum biogenesis	P	A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a primary cell septum following nuclear division.
31672	A band	C	The dark-staining region of a sarcomere, in which myosin thick filaments are present; the center is traversed by the paler H zone, which in turn contains the M line.
31673	H zone	C	A relatively pale zone traversing the center of the A band of a sarcomere, visible in relaxed muscle fibers; consists of the central portion of thick (myosin) filaments that are not overlapped by thin (actin) filaments.
31674	I band	C	A region of a sarcomere that appears as a light band on each side of the Z disc, comprising a region of the sarcomere where thin (actin) filaments are not overlapped by thick (myosin) filaments; contains actin, troponin, and tropomyosin; each sarcomere includes half of an I band at each end.
31676	plasma membrane-derived thylakoid membrane	C	The pigmented membrane of a plasma membrane-derived thylakoid.
31679	NADH dehydrogenase (plastoquinone) activity	F	Catalysis of the reaction: NADH + H+ + plastoquinone = NAD+ + plastoquinol.
31680	G-protein beta/gamma-subunit complex	C	The heterodimer formed by the beta and gamma subunits of a heterotrimeric G protein, which dissociates from the alpha subunit upon guanine nuclotide exchange.
31681	G-protein beta-subunit binding	F	Interacting selectively and non-covalently with a G-protein beta subunit.
31682	G-protein gamma-subunit binding	F	Interacting selectively and non-covalently with a G-protein gamma subunit.
31683	G-protein beta/gamma-subunit complex binding	F	Interacting selectively and non-covalently with a complex of G-protein beta/gamma subunits.
31684	heterotrimeric G-protein complex cycle	P	The series of molecular events that generate a signal through the activation of G-protein subunits and recycling of these subunits.
31685	adenosine receptor binding	F	Interacting selectively and non-covalently with an adenosine receptor.
31686	A1 adenosine receptor binding	F	Interacting selectively and non-covalently with an A1 adenosine receptor.
31687	A2A adenosine receptor binding	F	Interacting selectively and non-covalently with an A2A adenosine receptor.
31688	A2B adenosine receptor binding	F	Interacting selectively and non-covalently with an A2B adenosine receptor.
31689	A3 adenosine receptor binding	F	Interacting selectively and non-covalently with an A3 adenosine receptor.
31690	adrenergic receptor binding	F	Interacting selectively and non-covalently with an adrenergic receptor.
31691	alpha-1A adrenergic receptor binding	F	Interacting selectively and non-covalently with an alpha-1A adrenergic receptor.
31692	alpha-1B adrenergic receptor binding	F	Interacting selectively and non-covalently with an alpha-1B adrenergic receptor.
31693	alpha-1D adrenergic receptor binding	F	Interacting selectively and non-covalently with an alpha-1D adrenergic receptor.
31694	alpha-2A adrenergic receptor binding	F	Interacting selectively and non-covalently with an alpha-2A adrenergic receptor.
31695	alpha-2B adrenergic receptor binding	F	Interacting selectively and non-covalently with an alpha-2B adrenergic receptor.
31696	alpha-2C adrenergic receptor binding	F	Interacting selectively and non-covalently with an alpha-2C adrenergic receptor.
31697	beta-1 adrenergic receptor binding	F	Interacting selectively and non-covalently with a beta-1 adrenergic receptor.
31698	beta-2 adrenergic receptor binding	F	Interacting selectively and non-covalently with a beta-2 adrenergic receptor.
31699	beta-3 adrenergic receptor binding	F	Interacting selectively and non-covalently with a beta-3 adrenergic receptor.
31700	adrenomedullin receptor binding	F	Interacting selectively and non-covalently with an adrenomedullin receptor.
31701	angiotensin receptor binding	F	Interacting selectively and non-covalently with an angiotensin receptor.
31702	type 1 angiotensin receptor binding	F	Interacting selectively and non-covalently with a type 1 angiotensin receptor.
31703	type 2 angiotensin receptor binding	F	Interacting selectively and non-covalently with a type 2 angiotensin receptor.
31704	apelin receptor binding	F	Interacting selectively and non-covalently with an apelin receptor.
31705	bombesin receptor binding	F	Interacting selectively and non-covalently with a bombesin receptor.
31706	subtype 3 bombesin receptor binding	F	Interacting selectively and non-covalently with a subtype 3 bombesin receptor.
31707	endothelin A receptor binding	F	Interacting selectively and non-covalently with an endothelin A receptor.
31708	endothelin B receptor binding	F	Interacting selectively and non-covalently with an endothelin B receptor.
31709	gastrin-releasing peptide receptor binding	F	Interacting selectively and non-covalently with a gastrin-releasing peptide receptor.
31710	neuromedin B receptor binding	F	Interacting selectively and non-covalently with a neuromedin B receptor.
31711	bradykinin receptor binding	F	Interacting selectively and non-covalently with a bradykinin receptor.
31712	B1 bradykinin receptor binding	F	Interacting selectively and non-covalently with a B1 bradykinin receptor.
31713	B2 bradykinin receptor binding	F	Interacting selectively and non-covalently with a B2 bradykinin receptor.
31714	C5a anaphylatoxin chemotactic receptor binding	F	Interacting selectively and non-covalently with a C5a anaphylatoxin chemotactic receptor.
31715	C5L2 anaphylatoxin chemotactic receptor binding	F	Interacting selectively and non-covalently with a C5L2 anaphylatoxin chemotactic receptor.
31716	calcitonin receptor binding	F	Interacting selectively and non-covalently with a calcitonin receptor.
31717	cannabinoid receptor binding	F	Interacting selectively and non-covalently with a cannabinoid receptor.
31718	type 1 cannabinoid receptor binding	F	Interacting selectively and non-covalently with a type 1 cannabinoid receptor.
31719	type 2 cannabinoid receptor binding	F	Interacting selectively and non-covalently with a type 2 cannabinoid receptor.
31720	haptoglobin binding	F	Interacting selectively and non-covalently with a haptoglobin, any alpha2 globulin of blood plasma that can combine with free oxyhemoglobin to form a stable complex.
31721	hemoglobin alpha binding	F	Interacting selectively and non-covalently with a hemoglobin alpha chain.
31722	hemoglobin beta binding	F	Interacting selectively and non-covalently with a hemoglobin beta chain.
31723	CXCR4 chemokine receptor binding	F	Interacting selectively and non-covalently with a CXCR4 chemokine receptor.
31724	CXCR5 chemokine receptor binding	F	Interacting selectively and non-covalently with a CXCR5 chemokine receptor.
31725	CXCR6 chemokine receptor binding	F	Interacting selectively and non-covalently with a CXCR6 chemokine receptor.
31726	CCR1 chemokine receptor binding	F	Interacting selectively and non-covalently with a CCR1 chemokine receptor.
31727	CCR2 chemokine receptor binding	F	Interacting selectively and non-covalently with a CCR2 chemokine receptor.
31728	CCR3 chemokine receptor binding	F	Interacting selectively and non-covalently with a CCR3 chemokine receptor.
31729	CCR4 chemokine receptor binding	F	Interacting selectively and non-covalently with a CCR4 chemokine receptor.
31730	CCR5 chemokine receptor binding	F	Interacting selectively and non-covalently with a CCR5 chemokine receptor.
31731	CCR6 chemokine receptor binding	F	Interacting selectively and non-covalently with a CCR6 chemokine receptor.
31732	CCR7 chemokine receptor binding	F	Interacting selectively and non-covalently with a CCR7 chemokine receptor.
31733	CCR8 chemokine receptor binding	F	Interacting selectively and non-covalently with a CCR8 chemokine receptor.
31734	CCR9 chemokine receptor binding	F	Interacting selectively and non-covalently with a CCR9 chemokine receptor.
31735	CCR10 chemokine receptor binding	F	Interacting selectively and non-covalently with a CCR10 chemokine receptor.
31736	CCR11 chemokine receptor binding	F	Interacting selectively and non-covalently with a CCR11 chemokine receptor.
31737	CX3C chemokine receptor binding	F	Interacting selectively and non-covalently with a CX3C chemokine receptor.
31738	XCR1 chemokine receptor binding	F	Interacting selectively and non-covalently with a XCR1 chemokine receptor.
31739	cholecystokinin receptor binding	F	Interacting selectively and non-covalently with a cholecystokinin receptor.
31740	type A cholecystokinin receptor binding	F	Interacting selectively and non-covalently with a type A cholecystokinin receptor.
31741	type B gastrin/cholecystokinin receptor binding	F	Interacting selectively and non-covalently with a type B gastrin/cholecystokinin receptor.
31745	cysteinyl leukotriene receptor binding	F	Interacting selectively and non-covalently with a cysteinyl leukotriene receptor.
31746	type 1 cysteinyl leukotriene receptor binding	F	Interacting selectively and non-covalently with a type 1 cysteinyl leukotriene receptor.
31747	type 2 cysteinyl leukotriene receptor binding	F	Interacting selectively and non-covalently with a type 2 cysteinyl leukotriene receptor.
31748	D1 dopamine receptor binding	F	Interacting selectively and non-covalently with a D1 dopamine receptor.
31749	D2 dopamine receptor binding	F	Interacting selectively and non-covalently with a D2 dopamine receptor.
31750	D3 dopamine receptor binding	F	Interacting selectively and non-covalently with a D3 dopamine receptor.
31751	D4 dopamine receptor binding	F	Interacting selectively and non-covalently with a D4 dopamine receptor.
31752	D5 dopamine receptor binding	F	Interacting selectively and non-covalently with a D5 dopamine receptor.
31753	endothelial differentiation G-protein coupled receptor binding	F	Interacting selectively and non-covalently with an endothelial differentiation G-protein coupled receptor.
31754	Edg-1 sphingosine 1-phosphate receptor binding	F	Interacting selectively and non-covalently with an Edg-1 sphingosine 1-phosphate receptor.
31755	Edg-2 lysophosphatidic acid receptor binding	F	Interacting selectively and non-covalently with an Edg-2 lysophosphatidic acid receptor.
31756	Edg-3 sphingosine 1-phosphate receptor binding	F	Interacting selectively and non-covalently with an Edg-3 sphingosine 1-phosphate receptor.
31757	Edg-4 lysophosphatidic acid receptor binding	F	Interacting selectively and non-covalently with an Edg-4 lysophosphatidic acid receptor.
31758	Edg-5 sphingosine 1-phosphate receptor binding	F	Interacting selectively and non-covalently with an Edg-5 sphingosine 1-phosphate receptor.
31759	Edg-6 sphingosine 1-phosphate receptor binding	F	Interacting selectively and non-covalently with an Edg-6 sphingosine 1-phosphate receptor.
31760	Edg-7 lysophosphatidic acid receptor binding	F	Interacting selectively and non-covalently with an Edg-7 lysophosphatidic acid receptor.
31761	fMet-Leu-Phe receptor binding	F	Interacting selectively and non-covalently with a fMet-Leu-Phe receptor.
31762	follicle-stimulating hormone receptor binding	F	Interacting selectively and non-covalently with a follicle-stimulating hormone receptor.
31763	galanin receptor binding	F	Interacting selectively and non-covalently with a galanin receptor.
31764	type 1 galanin receptor binding	F	Interacting selectively and non-covalently with a type 1 galanin receptor.
31765	type 2 galanin receptor binding	F	Interacting selectively and non-covalently with a type 2 galanin receptor.
31766	type 3 galanin receptor binding	F	Interacting selectively and non-covalently with a type 3 galanin receptor.
31767	gastric inhibitory polypeptide receptor binding	F	Interacting selectively and non-covalently with a gastric inhibitory polypeptide receptor.
31768	ghrelin receptor binding	F	Interacting selectively and non-covalently with a ghrelin receptor.
31769	glucagon receptor binding	F	Interacting selectively and non-covalently with a glucagon receptor.
31770	growth hormone-releasing hormone receptor binding	F	Interacting selectively and non-covalently with a growth hormone-releasing hormone receptor.
31771	type 1 hypocretin receptor binding	F	Interacting selectively and non-covalently with a type 1 hypocretin receptor.
31772	type 2 hypocretin receptor binding	F	Interacting selectively and non-covalently with a type 2 hypocretin receptor.
31773	kisspeptin receptor binding	F	Interacting selectively and non-covalently with a kisspeptin receptor.
31774	leukotriene receptor binding	F	Interacting selectively and non-covalently with a leukotriene receptor.
31775	lutropin-choriogonadotropic hormone receptor binding	F	Interacting selectively and non-covalently with a lutropin-choriogonadotropic hormone receptor.
31776	melanin-concentrating hormone receptor binding	F	Interacting selectively and non-covalently with a melanin-concentrating hormone receptor.
31777	type 1 melanin-concentrating hormone receptor binding	F	Interacting selectively and non-covalently with a type 1 melanin-concentrating hormone receptor.
31778	type 2 melanin-concentrating hormone receptor binding	F	Interacting selectively and non-covalently with a type 2 melanin-concentrating hormone receptor.
31779	melanocortin receptor binding	F	Interacting selectively and non-covalently with a melanocortin receptor.
31780	corticotropin hormone receptor binding	F	Interacting selectively and non-covalently with a corticotropin hormone receptor.
31781	type 3 melanocortin receptor binding	F	Interacting selectively and non-covalently with a type 3 melanocortin receptor.
31782	type 4 melanocortin receptor binding	F	Interacting selectively and non-covalently with a type 4 melanocortin receptor.
31783	type 5 melanocortin receptor binding	F	Interacting selectively and non-covalently with a type 5 melanocortin receptor.
31784	melatonin receptor binding	F	Interacting selectively and non-covalently with a melatonin receptor.
31785	type 1A melatonin receptor binding	F	Interacting selectively and non-covalently with a type 1A melatonin receptor.
31786	type 1B melatonin receptor binding	F	Interacting selectively and non-covalently with a type 1B melatonin receptor.
31787	H9 melatonin receptor binding	F	Interacting selectively and non-covalently with a H9 melatonin receptor.
31788	motilin receptor binding	F	Interacting selectively and non-covalently with a motilin receptor.
31789	G-protein coupled acetylcholine receptor binding	F	Interacting selectively and non-covalently with a G-protein coupled acetylcholine receptor.
31795	G-protein coupled GABA receptor binding	F	Interacting selectively and non-covalently with a G-protein coupled (metabotropic) GABA receptor.
31796	type 1 metabotropic GABA receptor binding	F	Interacting selectively and non-covalently with a type 1 metabotropic GABA receptor.
31797	type 2 metabotropic GABA receptor binding	F	Interacting selectively and non-covalently with a type 2 metabotropic GABA receptor.
31798	type 1 metabotropic glutamate receptor binding	F	Interacting selectively and non-covalently with a type 1 metabotropic glutamate receptor.
31799	type 2 metabotropic glutamate receptor binding	F	Interacting selectively and non-covalently with a type 2 metabotropic glutamate receptor.
31800	type 3 metabotropic glutamate receptor binding	F	Interacting selectively and non-covalently with a type 3 metabotropic glutamate receptor.
31801	type 4 metabotropic glutamate receptor binding	F	Interacting selectively and non-covalently with a type 4 metabotropic glutamate receptor.
31802	type 5 metabotropic glutamate receptor binding	F	Interacting selectively and non-covalently with a type 5 metabotropic glutamate receptor.
31803	type 6 metabotropic glutamate receptor binding	F	Interacting selectively and non-covalently with a type 6 metabotropic glutamate receptor.
31804	type 7 metabotropic glutamate receptor binding	F	Interacting selectively and non-covalently with a type 7 metabotropic glutamate receptor.
31805	type 8 metabotropic glutamate receptor binding	F	Interacting selectively and non-covalently with a type 8 metabotropic glutamate receptor.
31806	G-protein coupled histamine receptor binding	F	Interacting selectively and non-covalently with a G-protein coupled (metabotropic) histamine receptor.
31807	H1 histamine receptor binding	F	Interacting selectively and non-covalently with a H1 histamine receptor.
31808	H2 histamine receptor binding	F	Interacting selectively and non-covalently with a H2 histamine receptor.
31809	H3 histamine receptor binding	F	Interacting selectively and non-covalently with a H3 histamine receptor.
31810	H4 histamine receptor binding	F	Interacting selectively and non-covalently with a H4 histamine receptor.
31811	G-protein coupled nucleotide receptor binding	F	Interacting selectively and non-covalently with a G-protein coupled (metabotropic) nucleotide receptor.
31812	P2Y1 nucleotide receptor binding	F	Interacting selectively and non-covalently with a P2Y1 nucleotide receptor.
31813	P2Y2 nucleotide receptor binding	F	Interacting selectively and non-covalently with a P2Y2 nucleotide receptor.
31814	P2Y4 nucleotide receptor binding	F	Interacting selectively and non-covalently with a P2Y4 nucleotide receptor.
31815	P2Y5 nucleotide receptor binding	F	Interacting selectively and non-covalently with a P2Y5 nucleotide receptor.
31816	P2Y6 nucleotide receptor binding	F	Interacting selectively and non-covalently with a P2Y6 nucleotide receptor.
31817	P2Y8 nucleotide receptor binding	F	Interacting selectively and non-covalently with a P2Y8 nucleotide receptor.
31818	P2Y9 nucleotide receptor binding	F	Interacting selectively and non-covalently with a P2Y9 nucleotide receptor.
31819	P2Y10 nucleotide receptor binding	F	Interacting selectively and non-covalently with a P2Y10 nucleotide receptor.
31820	P2Y11 nucleotide receptor binding	F	Interacting selectively and non-covalently with a P2Y11 nucleotide receptor.
31821	G-protein coupled serotonin receptor binding	F	Interacting selectively and non-covalently with a metabotropic serotonin receptor.
31822	type 1B serotonin receptor binding	F	Interacting selectively and non-covalently with a type 1B serotonin receptor.
31823	type 1D serotonin receptor binding	F	Interacting selectively and non-covalently with a type 1D serotonin receptor.
31824	type 1E serotonin receptor binding	F	Interacting selectively and non-covalently with a type 1E serotonin receptor.
31825	type 1F serotonin receptor binding	F	Interacting selectively and non-covalently with a type 1F serotonin receptor.
31826	type 2A serotonin receptor binding	F	Interacting selectively and non-covalently with a type 2A serotonin receptor.
31827	type 2B serotonin receptor binding	F	Interacting selectively and non-covalently with a type 2B serotonin receptor.
31828	type 2C serotonin receptor binding	F	Interacting selectively and non-covalently with a type 2C serotonin receptor.
31829	type 4 serotonin receptor binding	F	Interacting selectively and non-covalently with a type 4 serotonin receptor.
31830	type 5A serotonin receptor binding	F	Interacting selectively and non-covalently with a type 5A serotonin receptor.
31831	type 5B serotonin receptor binding	F	Interacting selectively and non-covalently with a type 5B serotonin receptor.
31832	type 6 serotonin receptor binding	F	Interacting selectively and non-covalently with a type 6 serotonin receptor.
31833	type 7 serotonin receptor binding	F	Interacting selectively and non-covalently with a type 7 serotonin receptor.
31834	neurokinin receptor binding	F	Interacting selectively and non-covalently with a neurokinin receptor.
31835	substance P receptor binding	F	Interacting selectively and non-covalently with a substance P receptor.
31836	neuromedin K receptor binding	F	Interacting selectively and non-covalently with a neuromedin K receptor.
31837	substance K receptor binding	F	Interacting selectively and non-covalently with a substance K receptor.
31838	haptoglobin-hemoglobin complex	C	A protein complex formed by the stable binding of a haptoglobin to hemoglobin.
31839	type 1 neuromedin U receptor binding	F	Interacting selectively and non-covalently with a type 1 neuromedin U receptor.
31840	type 2 neuromedin U receptor binding	F	Interacting selectively and non-covalently with a type 2 neuromedin U receptor.
31841	neuropeptide Y receptor binding	F	Interacting selectively and non-covalently with a neuropeptide Y receptor.
31842	type 1 neuropeptide Y receptor binding	F	Interacting selectively and non-covalently with a type 1 neuropeptide Y receptor.
31843	type 2 neuropeptide Y receptor binding	F	Interacting selectively and non-covalently with a type 2 neuropeptide Y receptor.
31844	type 4 neuropeptide Y receptor binding	F	Interacting selectively and non-covalently with a type 4 neuropeptide Y receptor.
31845	type 5 neuropeptide Y receptor binding	F	Interacting selectively and non-covalently with a type 5 neuropeptide Y receptor.
31846	neurotensin receptor binding	F	Interacting selectively and non-covalently with a neurotensin receptor.
31847	type 1 neurotensin receptor binding	F	Interacting selectively and non-covalently with a type 1 neurotensin receptor.
31848	protection from non-homologous end joining at telomere	P	A process that prevents non-homologous end joining at telomere, thereby ensuring that telomeres do not fuse.
31849	olfactory receptor binding	F	Interacting selectively and non-covalently with an olfactory receptor.
31850	delta-type opioid receptor binding	F	Interacting selectively and non-covalently with a delta-type opioid receptor.
31851	kappa-type opioid receptor binding	F	Interacting selectively and non-covalently with a kappa-type opioid receptor.
31852	mu-type opioid receptor binding	F	Interacting selectively and non-covalently with a mu-type opioid receptor.
31853	nociceptin receptor binding	F	Interacting selectively and non-covalently with a nociceptin receptor.
31854	orexigenic neuropeptide QRFP receptor binding	F	Interacting selectively and non-covalently with an orexigenic neuropeptide QRFP receptor.
31855	oxytocin receptor binding	F	Interacting selectively and non-covalently with an oxytocin receptor.
31856	parathyroid hormone receptor binding	F	Interacting selectively and non-covalently with a parathyroid hormone receptor.
31857	type 1 parathyroid hormone receptor binding	F	Interacting selectively and non-covalently with a type 1 parathyroid hormone receptor.
31858	pituitary adenylate cyclase-activating polypeptide receptor binding	F	Interacting selectively and non-covalently with a pituitary adenylate cyclase-activating polypeptide receptor.
31859	platelet activating factor receptor binding	F	Interacting selectively and non-covalently with a platelet activating factor receptor.
31860	telomeric 3' overhang formation	P	The formation of the single stranded telomeric 3' overhang, a conserved feature that ranges in length from 12 nt in budding yeast to approximately 500 nt in humans.
31861	prolactin-releasing peptide receptor binding	F	Interacting selectively and non-covalently with a prolactin-releasing peptide receptor.
31862	prostanoid receptor binding	F	Interacting selectively and non-covalently with a prostanoid receptor.
31863	prostaglandin D2 receptor binding	F	Interacting selectively and non-covalently with a prostaglandin D2 receptor.
31864	EP1 subtype prostaglandin E2 receptor binding	F	Interacting selectively and non-covalently with an EP1 subtype prostaglandin E2 receptor.
31865	EP2 subtype prostaglandin E2 receptor binding	F	Interacting selectively and non-covalently with an EP2 subtype prostaglandin E2 receptor.
31866	EP3 subtype prostaglandin E2 receptor binding	F	Interacting selectively and non-covalently with an EP3 subtype prostaglandin E2 receptor.
31867	EP4 subtype prostaglandin E2 receptor binding	F	Interacting selectively and non-covalently with an EP4 subtype prostaglandin E2 receptor.
31868	prostaglandin F2-alpha receptor binding	F	Interacting selectively and non-covalently with a prostaglandin F2-alpha receptor.
31869	prostacyclin receptor binding	F	Interacting selectively and non-covalently with a prostacyclin receptor.
31870	thromboxane A2 receptor binding	F	Interacting selectively and non-covalently with a thromboxane A2 receptor.
31871	proteinase activated receptor binding	F	Interacting selectively and non-covalently with a proteinase activated receptor.
31872	type 1 proteinase activated receptor binding	F	Interacting selectively and non-covalently with a type 1 proteinase activated receptor.
31873	type 2 proteinase activated receptor binding	F	Interacting selectively and non-covalently with a type 2 proteinase activated receptor.
31874	type 3 proteinase activated receptor binding	F	Interacting selectively and non-covalently with a type 3 proteinase activated receptor.
31875	type 4 proteinase activated receptor binding	F	Interacting selectively and non-covalently with a type 4 proteinase activated receptor.
31876	secretin receptor binding	F	Interacting selectively and non-covalently with a secretin receptor.
31877	somatostatin receptor binding	F	Interacting selectively and non-covalently with a somatostatin receptor.
31878	type 1 somatostatin receptor binding	F	Interacting selectively and non-covalently with a type 1 somatostatin receptor.
31879	type 2 somatostatin receptor binding	F	Interacting selectively and non-covalently with a type 2 somatostatin receptor.
31880	type 3 somatostatin receptor binding	F	Interacting selectively and non-covalently with a type 3 somatostatin receptor.
31881	type 4 somatostatin receptor binding	F	Interacting selectively and non-covalently with a type 4 somatostatin receptor.
31882	type 5 somatostatin receptor binding	F	Interacting selectively and non-covalently with a type 5 somatostatin receptor.
31883	taste receptor binding	F	Interacting selectively and non-covalently with a taste receptor.
31884	type 1 member 1 taste receptor binding	F	Interacting selectively and non-covalently with a type 1 member 1 taste receptor.
31885	type 1 member 2 taste receptor binding	F	Interacting selectively and non-covalently with a type 1 member 2 taste receptor.
31886	type 1 member 3 taste receptor binding	F	Interacting selectively and non-covalently with a type 1 member 3 taste receptor.
31887	lipid particle transport along microtubule	P	The directed movement of a lipid particle along a microtubule, mediated by motor proteins.
31889	urotensin receptor binding	F	Interacting selectively and non-covalently with a urotensin receptor.
31890	vasoactive intestinal polypeptide receptor binding	F	Interacting selectively and non-covalently with a vasoactive intestinal polypeptide receptor.
31891	type 1 vasoactive intestinal polypeptide receptor binding	F	Interacting selectively and non-covalently with a type 1 vasoactive intestinal polypeptide receptor.
31892	type 2 vasoactive intestinal polypeptide receptor binding	F	Interacting selectively and non-covalently with a type 2 vasoactive intestinal polypeptide receptor.
31893	vasopressin receptor binding	F	Interacting selectively and non-covalently with a vasopressin receptor.
31894	V1A vasopressin receptor binding	F	Interacting selectively and non-covalently with a V1A vasopressin receptor.
31895	V1B vasopressin receptor binding	F	Interacting selectively and non-covalently with a V1B vasopressin receptor.
31896	V2 vasopressin receptor binding	F	Interacting selectively and non-covalently with a V2 vasopressin receptor.
31897	Tic complex	C	The translocon of the inner envelope of chloroplasts, which facilitates the import of proteins across the chloroplast inner membrane.
31898	chromoplast envelope	C	The double lipid bilayer enclosing the chromoplast and separating its contents from the rest of the cytoplasm; includes the intermembrane space.
31899	chromoplast inner membrane	C	The inner, i.e. lumen-facing, lipid bilayer of the chromoplast envelope; also faces the chromoplast stroma.
31900	chromoplast outer membrane	C	The outer, i.e. cytoplasm-facing, lipid bilayer of the chromoplast envelope.
31901	early endosome membrane	C	The lipid bilayer surrounding an early endosome.
31902	late endosome membrane	C	The lipid bilayer surrounding a late endosome.
31903	microbody membrane	C	The lipid bilayer surrounding a microbody.
31904	endosome lumen	C	The volume enclosed by the membrane of an endosome.
31905	early endosome lumen	C	The volume enclosed by the membrane of an early endosome.
31906	late endosome lumen	C	The volume enclosed by the membrane of a late endosome.
31907	microbody lumen	C	The volume enclosed by the membranes of a microbody.
31908	glyoxysomal lumen	C	The volume enclosed by the membranes of a glyoxysome.
31910	cytostome	C	Stable, specialized structure for the ingestion of food by the cell into phagosomes.
31911	cytoproct	C	Stable, specialized structure for extrusion of waste by the cell into the surrounding medium.
31912	oral apparatus	C	Complex basket- or funnel-like structure used by the cell to collect food and channel it to the cytostome; includes specialized sub-structures made up of closely-spaced cilia and underlying basal bodies and fibrillar systems.
31913	contractile vacuole pore	C	Stable structure that regulates the flow of liquid between the contractile vacuole and the surrounding medium.
31914	negative regulation of synaptic plasticity	P	A process that decreases synaptic plasticity, the ability of synapses to change as circumstances require. They may alter function, such as increasing or decreasing their sensitivity, or they may increase or decrease in actual numbers.
31915	positive regulation of synaptic plasticity	P	A process that increases synaptic plasticity, the ability of synapses to change as circumstances require. They may alter function, such as increasing or decreasing their sensitivity, or they may increase or decrease in actual numbers.
31916	regulation of synaptic metaplasticity	P	A process that modulates synaptic metaplasticity. Metaplasticity is a higher-order form of plasticity and is manifest as a change in the ability to induce subsequent synaptic plasticity that is the ability of synapses to change as circumstances require.
31917	negative regulation of synaptic metaplasticity	P	A process that decreases synaptic metaplasticity. Metaplasticity is a higher-order form of plasticity and is manifest as a change in the ability to induce subsequent synaptic plasticity that is the ability of synapses to change as circumstances require.
31918	positive regulation of synaptic metaplasticity	P	A process that increases synaptic metaplasticity. Metaplasticity is a higher-order form of plasticity and is manifest as a change in the ability to induce subsequent synaptic plasticity that is the ability of synapses to change as circumstances require.
31919	vitamin B6 transport	P	The directed movement of any of the vitamin B6 compounds -- pyridoxal, pyridoxamine and pyridoxine and the active form, pyridoxal phosphate -- into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
31920	pyridoxal transport	P	The directed movement of pyridoxal into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Pyridoxal, 3-hydroxy-5-(hydroxymethyl)-2-methyl-4-pyridinecarboxaldehyde, is one of the vitamin B6 compounds. Pyridoxal, pyridoxamine and pyridoxine are collectively known as vitamin B6, and are efficiently converted to the biologically active form of vitamin B6, pyridoxal phosphate.
31921	pyridoxal phosphate transport	P	The directed movement of pyridoxal phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore; pyridoxal phosphate is pyridoxal phosphorylated at the hydroxymethyl group of C-5, and is the active form of vitamin B6.
31922	pyridoxamine transport	P	The directed movement of pyridoxamine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Pyridoxamine, 4-(aminomethyl)-5-(hydroxymethyl)-2-methylpyridin-3-ol, is one of the vitamin B6 compounds. Pyridoxal, pyridoxamine and pyridoxine are collectively known as vitamin B6, and are efficiently converted to the biologically active form of vitamin B6, pyridoxal phosphate.
31923	pyridoxine transport	P	The directed movement of pyridoxine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Pyridoxine, 2-methyl-3-hydroxy-4,5-bis(hydroxymethyl)pyridine, is one of the vitamin B6 compounds. Pyridoxal, pyridoxamine and pyridoxine are collectively known as vitamin B6, and are efficiently converted to the biologically active form of vitamin B6, pyridoxal phosphate.
31924	vitamin B6 transporter activity	F	Enables the directed movement of any of the vitamin B6 compounds -- pyridoxal, pyridoxamine and pyridoxine and the active form, pyridoxal phosphate -- into, out of or within a cell, or between cells.
31925	pyridoxal transmembrane transporter activity	F	Enables the directed movement of pyridoxal across a membrane into, out of or within a cell, or between cells. Pyridoxal, 3-hydroxy-5-(hydroxymethyl)-2-methyl-4-pyridinecarboxaldehyde, is one of the vitamin B6 compounds. Pyridoxal, pyridoxamine and pyridoxine are collectively known as vitamin B6, and are efficiently converted to the biologically active form of vitamin B6, pyridoxal phosphate.
31926	pyridoxal phosphate transmembrane transporter activity	F	Enables the directed movement of pyridoxal phosphate into, out of or within a cell, or between cells; pyridoxal phosphate is pyridoxal phosphorylated at the hydroxymethyl group of C-5, and is the active form of vitamin B6.
31927	pyridoxamine transmembrane transporter activity	F	Enables the directed movement of pyridoxamine into, out of or within a cell, or between cells. Pyridoxamine, 4-(aminomethyl)-5-(hydroxymethyl)-2-methylpyridin-3-ol, is one of the vitamin B6 compounds. Pyridoxal, pyridoxamine and pyridoxine are collectively known as vitamin B6, and are efficiently converted to the biologically active form of vitamin B6, pyridoxal phosphate.
31928	pyridoxine transmembrane transporter activity	F	Enables the directed movement of pyridoxine across a membrane into, out of or within a cell, or between cells. Pyridoxine, 2-methyl-3-hydroxy-4,5-bis(hydroxymethyl)pyridine, is one of the vitamin B6 compounds. Pyridoxal, pyridoxamine and pyridoxine are collectively known as vitamin B6, and are efficiently converted to the biologically active form of vitamin B6, pyridoxal phosphate.
31929	TOR signaling	P	A series of molecular signals mediated by TOR (Target of rapamycin) proteins, members of the phosphoinositide (PI) 3-kinase related kinase (PIKK) family that act as serine/threonine kinases in response to nutrient availability or growth factors.
31930	mitochondria-nucleus signaling pathway	P	A series of molecular signals that forms a pathway of communication from the mitochondria to the nucleus and initiates cellular changes in response to changes in mitochondrial function.
31931	TORC1 complex	C	A protein complex that contains at least TOR (target of rapamycin) and Raptor (regulatory-associated protein of TOR), or orthologs of, in complex with other signaling components. Mediates the phosphorylation and activation of S6K. In Saccharomyces, the complex contains Kog1p, Lst8p, Tco89p, and either Tor1p or Tor2p.
31932	TORC2 complex	C	A protein complex that contains at least TOR (target of rapamycin) and Rictor (rapamycin-insensitive companion of TOR), or orthologs of, in complex with other signaling components. Mediates the phosphorylation and activation of PKB (also called AKT). In Saccharomyces, the complex contains Avo1p, Avo2p, Tsc11p, Lst8p, Bit61p, Slm1p, Slm2p, and Tor2p.
31933	telomeric heterochromatin	C	Heterochromatic regions of the chromosome found at the telomeres.
31934	mating-type region heterochromatin	C	Heterochromatic regions of the chromosome found at silenced mating-type loci.
31935	regulation of chromatin silencing	P	Any process that affects the rate, extent or location of chromatin silencing.
31936	negative regulation of chromatin silencing	P	Any process that stops, prevents, or reduces the frequency, rate or extent of chromatin silencing.
31937	positive regulation of chromatin silencing	P	Any process that activates or increases the frequency, rate or extent of chromatin silencing.
31938	regulation of chromatin silencing at telomere	P	Any process that affects the rate, extent or location of chromatin silencing at telomeres.
31939	negative regulation of chromatin silencing at telomere	P	Any process that stops, prevents, or reduces the frequency, rate or extent of chromatin silencing at telomeres.
31940	positive regulation of chromatin silencing at telomere	P	Any process that activates or increases the frequency, rate or extent of chromatin silencing at telomeres.
31941	filamentous actin	C	A two-stranded helical polymer of the protein actin.
31942	i-AAA complex	C	Protease complex of the mitochondrial inner membrane whose catalytic residues lie on the intermembrane space side of the inner membrane; involved in mitochondrial protein turnover. Contains a subunit belonging to the AAA family of ATP-dependent metalloproteases.
31943	regulation of glucocorticoid metabolic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving glucocorticoids.
31944	negative regulation of glucocorticoid metabolic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving glucocorticoids.
31945	positive regulation of glucocorticoid metabolic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving glucocorticoids.
31946	regulation of glucocorticoid biosynthetic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glucocorticoids.
31947	negative regulation of glucocorticoid biosynthetic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glucocorticoids.
31948	positive regulation of glucocorticoid biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glucocorticoids.
31949	regulation of glucocorticoid catabolic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glucocorticoids.
31950	negative regulation of glucocorticoid catabolic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glucocorticoids.
31951	positive regulation of glucocorticoid catabolic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glucocorticoids.
31952	regulation of protein autophosphorylation	P	Any process that modulates the frequency, rate or extent of addition of the phosphorylation by a protein of one or more of its own residues.
31953	negative regulation of protein autophosphorylation	P	Any process that stops, prevents or decreases the rate of the phosphorylation by a protein of one or more of its own residues.
31954	positive regulation of protein autophosphorylation	P	Any process that activates or increases the frequency, rate or extent of the phosphorylation by a protein of one or more of its own residues.
31955	short-chain fatty acid-CoA ligase activity	F	Catalysis of the reaction: ATP + a short-chain carboxylic acid + CoA = AMP + diphosphate + an acyl-CoA; short-chain fatty acids are fatty acids with a chain length of less than C6.
31956	medium-chain fatty acid-CoA ligase activity	F	Catalysis of the reaction: ATP + a medium-chain carboxylic acid + CoA = AMP + diphosphate + an acyl-CoA; a medium-chain fatty acid is any fatty acid with a chain length of between C6 and C12.
31957	very long-chain fatty acid-CoA ligase activity	F	Catalysis of the reaction: ATP + a very-long-chain carboxylic acid + CoA = AMP + diphosphate + an acyl-CoA; a very long-chain fatty acid is a fatty acid which has a chain length greater than C22.
31958	corticosteroid receptor signaling pathway	P	Any series of molecular signals generated as a consequence of a corticosteroid binding to its receptor.
31959	mineralocorticoid receptor signaling pathway	P	Any series of molecular signals generated as a consequence of a mineralocorticoid binding to its receptor.
31960	response to corticosteroid	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a corticosteroid hormone stimulus. A corticosteroid is a steroid hormone that is produced in the adrenal cortex. Corticosteroids are involved in a wide range of physiologic systems such as stress response, immune response and regulation of inflammation, carbohydrate metabolism, protein catabolism, blood electrolyte levels, and behavior. They include glucocorticoids and mineralocorticoids.
31961	cortisol receptor binding	F	Interacting selectively and non-covalently with a cortisol receptor.
31962	mineralocorticoid receptor binding	F	Interacting selectively and non-covalently with a mineralocorticoid receptor.
31963	cortisol receptor activity	F	Combining with cortisol and transmitting the signal within the cell to trigger a change in cell activity or function.
31964	beta-alanyl-histamine hydrolase activity	F	Catalysis of the reaction: N-beta-alanyl histamine + H2O = histamine + beta-alanine.
31965	nuclear membrane	C	Either of the lipid bilayers that surround the nucleus and form the nuclear envelope; excludes the intermembrane space.
31966	mitochondrial membrane	C	Either of the lipid bilayers that surround the mitochondrion and form the mitochondrial envelope.
31967	organelle envelope	C	A double membrane structure enclosing an organelle, including two lipid bilayers and the region between them. In some cases, an organelle envelope may have more than two membranes.
31968	organelle outer membrane	C	The outer, i.e. cytoplasm-facing in a cellular organelle, lipid bilayer of an organelle envelope.
31969	chloroplast membrane	C	Either of the lipid bilayers that surround a chloroplast and form the chloroplast envelope.
31970	organelle envelope lumen	C	The region between the inner and outer lipid bilayers of an organelle envelope.
31972	chloroplast intermembrane space	C	The region between the inner and outer lipid bilayers of a chloroplast envelope.
31973	chromoplast intermembrane space	C	The region between the inner and outer lipid bilayers of a chromoplast envelope.
31974	membrane-enclosed lumen	C	The enclosed volume within a sealed membrane or between two sealed membranes. Encompasses the volume enclosed by the membranes of a particular organelle, e.g. endoplasmic reticulum lumen, or the space between the two lipid bilayers of a double membrane surrounding an organelle, e.g. nuclear envelope lumen.
31975	envelope	C	A multilayered structure surrounding all or part of a cell; encompasses one or more lipid bilayers, and may include a cell wall layer; also includes the space between layers.
31976	plastid thylakoid	C	Any thylakoid within a plastid.
31977	thylakoid lumen	C	The volume enclosed by a thylakoid membrane.
31978	plastid thylakoid lumen	C	The volume enclosed by a plastid thylakoid membrane.
31979	plasma membrane-derived thylakoid lumen	C	The volume enclosed by a plasma membrane-derived thylakoid.
31981	nuclear lumen	C	The volume enclosed by the nuclear inner membrane.
31982	vesicle	C	Any small, fluid-filled, spherical organelle enclosed by membrane.
31983	vesicle lumen	C	The volume enclosed by the membrane or protein that forms a vesicle.
31984	organelle subcompartment	C	A compartment that consists of a lumen and an enclosing membrane, and is part of an organelle.
31985	Golgi cisterna	C	Any of the thin, flattened membrane-bounded compartments that form the central portion of the Golgi complex.
31986	proteinoplast	C	A leucoplast in which protein is stored.
31987	locomotion involved in locomotory behavior	P	Self-propelled movement of a cell or organism from one location to another in a behavioral context; the aspect of locomotory behavior having to do with movement.
31989	bombesin receptor signaling pathway	P	The series of molecular signals generated as a consequence of a bombesin receptor binding to one of its physiological ligands.
31990	mRNA export from nucleus in response to heat stress	P	The directed movement of mRNA from the nucleus to the cytoplasm during a heat stimulus, a temperature stimulus above the optimal temperature for the organism; in particular, a process that enables an organism withstand exposure to temperatures that would otherwise lethally impair poly(A)+ mRNA-nucleus export.
31991	regulation of actomyosin contractile ring contraction	P	Any process that modulates the frequency, rate or extent of contraction of the actomyosin ring involved in cytokinesis that takes place as part of a cell cycle.
31992	energy transducer activity	F	The biological transducer activity that accepts energy and converts it to another form, often by transfer to another molecule within the cell.
31993	light transducer activity	F	Absorbing energy from one or more photons and transferring their energy to another molecule, usually a protein, within the cell.
31994	insulin-like growth factor I binding	F	Interacting selectively and non-covalently with insulin-like growth factor I.
31995	insulin-like growth factor II binding	F	Interacting selectively and non-covalently with insulin-like growth factor II.
31996	thioesterase binding	F	Interacting selectively and non-covalently with any thioesterase enzyme.
31997	N-terminal myristoylation domain binding	F	Interacting selectively and non-covalently with the N-terminus of a protein that has the potential to be, or has been, modified by N-terminal myristoylation. Binding affinity is typically altered by myristoylation; for example, N-terminal myristoylation of HIV Nef increases its affinity for calmodulin.
31998	regulation of fatty acid beta-oxidation	P	Any process that modulates the frequency, rate or extent of fatty acid bbeta-oxidation.
31999	negative regulation of fatty acid beta-oxidation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of fatty acid beta-oxidation.
32000	positive regulation of fatty acid beta-oxidation	P	Any process that activates or increases the frequency, rate or extent of fatty acid beta-oxidation.
32001	1,4-alpha-glucan 6-alpha-glucosyltransferase activity	F	Catalysis of the transfer an alpha-D-glucosyl residue in a (1->4)-alpha-D-glucan to the primary hydroxy group of glucose, free or combined in a (1->4)-alpha-D-glucan.
32002	interleukin-28 receptor complex	C	A protein complex that binds interleukin-28 and interleukin-29. It is composed of an alpha and a beta receptor subunit (in human IFNLR1/IL28Ralpha & IL10RB) and either Interleukin-28 (IFNL2 or IFNL3) or Interleukin-29 (IFNL1).
32003	interleukin-28 receptor binding	F	Interacting selectively and non-covalently with the interleukin-28 receptor.
32005	signal transduction involved in conjugation with cellular fusion	P	The series of molecular signals that bring about the relay, amplification or dampening of a signal generated in response to a cue, such as starvation or pheromone exposure, in organisms that undergo conjugation with cellular fusion.
32006	regulation of TOR signaling	P	Any process that modulates the frequency, rate or extent of TOR signaling.
32007	negative regulation of TOR signaling	P	Any process that stops, prevents, or reduces the frequency, rate or extent of TOR signaling.
32008	positive regulation of TOR signaling	P	Any process that activates or increases the frequency, rate or extent of TOR signaling.
32009	early phagosome	C	A membrane-bounded intracellular vesicle as initially formed upon the ingestion of particulate material by phagocytosis.
32010	phagolysosome	C	A membrane-bounded intracellular vesicle formed by maturation of an early phagosome following the ingestion of particulate material by phagocytosis; during maturation, phagosomes acquire markers of late endosomes and lysosomes.
32011	ARF protein signal transduction	P	A series of molecular signals within the cell that are mediated by a member of the ARF family of proteins switching to a GTP-bound active state.
32012	regulation of ARF protein signal transduction	P	Any process that modulates the frequency, rate or extent of ARF protein signal transduction.
32013	negative regulation of ARF protein signal transduction	P	Any process that stops, prevents, or reduces the frequency, rate or extent of ARF protein signal transduction.
32014	positive regulation of ARF protein signal transduction	P	Any process that activates or increases the frequency, rate or extent of ARF protein signal transduction.
32015	regulation of Ran protein signal transduction	P	Any process that modulates the frequency, rate or extent of Ran protein signal transduction.
32016	negative regulation of Ran protein signal transduction	P	Any process that stops, prevents, or reduces the frequency, rate or extent of Ran protein signal transduction.
32017	positive regulation of Ran protein signal transduction	P	Any process that activates or increases the frequency, rate or extent of Ran protein signal transduction.
32018	2-methylbutanol:NADP oxidoreductase activity	F	Catalysis of the reaction: 2-methylbutanol + NADP+ = 2-methylbutanal + NADPH + H+.
32019	mitochondrial cloud	C	A prominent mass in the cytoplasm of previtellogenic oocytes. The cloud contains both mitochondria and electron-dense granulofibrillar material (GFM) and is the source of germinal granule material.
32020	ISG15-protein conjugation	P	The covalent addition to a protein of ISG15, a ubiquitin-like protein.
32021	NELF complex	C	A complex of five proteins, designated NELF-A, -B, -C, -D, and -E in human, that can physically associate with RNP polymerase II to induce transcriptional pausing.
32022	multicellular pellicle formation	P	A process in which microorganisms produce an extracellular matrix and form multicellular aggregates at an air-liquid interface.
32023	trypsinogen activation	P	The proteolytic processing of trypsinogen to the active form, trypsin.
32024	positive regulation of insulin secretion	P	Any process that activates or increases the frequency, rate or extent of the regulated release of insulin.
32025	response to cobalt ion	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cobalt ion stimulus.
32026	response to magnesium ion	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a magnesium ion stimulus.
32027	myosin light chain binding	F	Interacting selectively and non-covalently with a light chain of a myosin complex.
32028	myosin head/neck binding	F	Interacting selectively and non-covalently with the head/neck region of a myosin heavy chain.
32029	myosin tail binding	F	Interacting selectively and non-covalently with the tail region of a myosin heavy chain.
32030	myosin I light chain binding	F	Interacting selectively and non-covalently with a light chain of a myosin I complex.
32031	myosin I head/neck binding	F	Interacting selectively and non-covalently with the head/neck region of a myosin I heavy chain.
32032	myosin I tail binding	F	Interacting selectively and non-covalently with the tail region of a myosin I heavy chain.
32033	myosin II light chain binding	F	Interacting selectively and non-covalently with a light chain of a myosin II complex.
32034	myosin II head/neck binding	F	Interacting selectively and non-covalently with the head/neck region of a myosin II heavy chain.
32035	myosin II tail binding	F	Interacting selectively and non-covalently with the tail region of a myosin II heavy chain.
32036	myosin heavy chain binding	F	Interacting selectively and non-covalently with a heavy chain of a myosin complex.
32037	myosin I heavy chain binding	F	Interacting selectively and non-covalently with a heavy chain of a myosin I complex.
32038	myosin II heavy chain binding	F	Interacting selectively and non-covalently with a heavy chain of a myosin II complex.
32039	integrator complex	C	A protein complex that stably associates with the C-terminus of RNA polymerase II and mediates 3'-end processing of small nuclear RNAs generated by RNA polymerase II.
32040	small-subunit processome	C	A large ribonucleoprotein complex that is an early preribosomal complex. In S. cerevisiae, it has a size of 80S and consists of the 35S pre-rRNA, early-associating ribosomal proteins most of which are part of the small ribosomal subunit, the U3 snoRNA and associated proteins.
32041	NAD-dependent histone deacetylase activity (H3-K14 specific)	F	Catalysis of the reaction: histone H3 N6-acetyl-L-lysine (position 14) + H2O = histone H3 L-lysine (position 14) + acetate. This reaction requires the presence of NAD, and represents the removal of an acetyl group from lysine at position 14 of the histone H3 protein.
32042	mitochondrial DNA metabolic process	P	The chemical reactions and pathways involving mitochondrial DNA.
32043	mitochondrial DNA catabolic process	P	The chemical reactions and pathways resulting in the breakdown of mitochondrial DNA.
32044	DSIF complex	C	A heterodimeric protein complex formed of Spt4 and Spt5 proteins which is expressed in eukaryotes from yeast to man. DSIF is an inhibitory elongation factor that promotes RNA polymerase II transcriptional pausing, but can also stimulate transcriptional elongation under certain conditions, and may play a role in RNA processing via its physical association with mRNA capping enzymes.
32045	guanyl-nucleotide exchange factor complex	C	A protein complex that stimulates the exchange of guanyl nucleotides associated with a GTPase.
32046	micropexophagy-specific membrane apparatus	C	A membrane-bounded flattened sac that is formed during micropexophagy between the membrane tips of an engulfing vacuole, completing the engulfment and sequestration of peroxisomes from the cytosol, and forming a micropexophagic body within the lumen of the vacuole.
32047	mitosome	C	A double-membrane-bounded organelle that functions in iron-sulfur protein maturation; evolutionarily derived from mitochondria. The mitosome has been detected only in anaerobic or microaerophilic organisms that do not have mitochondria, such as Entamoeba histolytica, Giardia intestinalis and several species of Microsporidia. These organisms are not capable of gaining energy from oxidative phosphorylation, which is normally performed by mitochondria.
32048	cardiolipin metabolic process	P	The chemical reactions and pathways involving cardiolipin, 1,3-bis(3-phosphatidyl)glycerol.
32049	cardiolipin biosynthetic process	P	The chemical reactions and pathways resulting in the formation of cardiolipin, 1,3-bis(3-phosphatidyl)glycerol.
32050	clathrin heavy chain binding	F	Interacting selectively and non-covalently with a clathrin heavy chain.
32051	clathrin light chain binding	F	Interacting selectively and non-covalently with a clathrin light chain.
32052	bile acid binding	F	Interacting selectively and non-covalently with bile acids, any of a group of steroid carboxylic acids occurring in bile.
32053	ciliary basal body organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a ciliary basal body, a short cylindrical array of microtubules and associated proteins found at the base of a eukaryotic cilium (also called flagellum).
32055	negative regulation of translation in response to stress	P	Any process that stops, prevents or reduces the rate of translation as a result of a stimulus indicating the organism is under stress.
32056	positive regulation of translation in response to stress	P	Any process that activates or increases the frequency, rate or extent of translation as a result of a stimulus indicating the organism is under stress.
32057	negative regulation of translational initiation in response to stress	P	Any process that stops, prevents or reduces the rate of translation initiation as a result of a stimulus indicating the organism is under stress.
32058	positive regulation of translational initiation in response to stress	P	Any process that activates or increases the frequency, rate or extent of translation initiation as a result of a stimulus indicating the organism is under stress.
32059	bleb	C	A cell extension caused by localized decoupling of the cytoskeleton from the plasma membrane and characterized by rapid formation, rounded shape, and scarcity of organelles within the protrusion. Blebs are formed during apoptosis and other cellular processes, including cell locomotion, cell division, and as a result of physical or chemical stresses.
32060	bleb assembly	P	The assembly of a bleb, a cell extension caused by localized decoupling of the cytoskeleton from the plasma membrane and characterized by rapid formation, rounded shape, and scarcity of organelles within the protrusion. Plasma membrane blebbing occurs during apoptosis and other cellular processes, including cell locomotion, cell division, and as a result of physical or chemical stresses.
32061	negative regulation of translation in response to osmotic stress	P	Any process that stops, prevents or reduces the rate of translation as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell.
32062	positive regulation of translation in response to osmotic stress	P	Any process that activates or increases the frequency, rate or extent of translation as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell.
32063	negative regulation of translational initiation in response to osmotic stress	P	Any process that stops, prevents or reduces the rate of translation initiation, as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell.
32064	positive regulation of translational initiation in response to osmotic stress	P	Any process that activates or increases the frequency, rate or extent of translation initiation, as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell.
32065	cortical protein anchoring	P	A process in which a protein or protein complex is maintained in a specific location in the cell cortex.
32066	nucleolus to nucleoplasm transport	P	The directed movement of substances from the nucleolus to the nucleoplasm.
32067	Type IV site-specific deoxyribonuclease activity	F	Catalysis of the endonucleolytic cleavage of DNA in a site specific manner. Cleavage is dependent on the presence of a specific recognition site in the DNA which must be modified (e.g. methylated, hydroxymethylated, glucosyl-hydroxymethylated).
32068	Type IV site-specific deoxyribonuclease complex	C	A complex consisting of two proteins which acts as an endonuclease in DNA sequences containing a specific modified recognition site. Modifications may include methylation, hydroxymethylation, and glucosyl-hydroxymethylation.
32069	regulation of nuclease activity	P	Any process that modulates the frequency, rate or extent of nuclease activity, the hydrolysis of ester linkages within nucleic acids.
32070	regulation of deoxyribonuclease activity	P	Any process that modulates the frequency, rate or extent of deoxyribonuclease activity, the hydrolysis of ester linkages within deoxyribonucleic acid.
32071	regulation of endodeoxyribonuclease activity	P	Any process that modulates the frequency, rate or extent of endodeoxyribonuclease activity, the hydrolysis of ester linkages within deoxyribonucleic acid by creating internal breaks.
32072	regulation of restriction endodeoxyribonuclease activity	P	Any process that modulates the frequency, rate or extent of a restriction endodeoxyribonuclease activity, the catalysis of endonucleolytic cleavage of DNA in a site-specific manner, resulting in double-strand breaks.
32073	negative regulation of restriction endodeoxyribonuclease activity	P	Any process that stops or reduces the rate of a restriction endodeoxyribonuclease activity, the catalysis of endonucleolytic cleavage of DNA in a site-specific manner, resulting in double-strand breaks.
32074	negative regulation of nuclease activity	P	Any process that stops or reduces the rate of nuclease activity, the hydrolysis of ester linkages within nucleic acids.
32075	positive regulation of nuclease activity	P	Any process that activates or increases the frequency, rate or extent of nuclease activity, the hydrolysis of ester linkages within nucleic acids.
32076	negative regulation of deoxyribonuclease activity	P	Any process that stops or reduces the rate of deoxyribonuclease activity, the hydrolysis of ester linkages within deoxyribonucleic acid.
32077	positive regulation of deoxyribonuclease activity	P	Any process that activates or increases the frequency, rate or extent of deoxyribonuclease activity, the hydrolysis of ester linkages within deoxyribonucleic acid.
32078	negative regulation of endodeoxyribonuclease activity	P	Any process that stops or reduces the rate of endodeoxyribonuclease activity, the hydrolysis of ester linkages within deoxyribonucleic acid by creating internal breaks.
32079	positive regulation of endodeoxyribonuclease activity	P	Any process that activates or increases the frequency, rate or extent of endodeoxyribonuclease activity, the hydrolysis of ester linkages within deoxyribonucleic acid by creating internal breaks.
32080	negative regulation of Type I site-specific deoxyribonuclease activity	P	Any process that stops or reduces the rate of Type I restriction endodeoxyribonuclease activity.
32081	negative regulation of Type II site-specific deoxyribonuclease activity	P	Any process that stops or reduces the rate of Type II restriction endodeoxyribonuclease activity.
32082	negative regulation of Type III site-specific deoxyribonuclease activity	P	Any process that stops or reduces the rate of Type III restriction endodeoxyribonuclease activity.
32083	negative regulation of Type IV site-specific deoxyribonuclease activity	P	Any process that stops or reduces the rate of Type IV restriction endodeoxyribonuclease activity.
32084	regulation of Type I site-specific deoxyribonuclease activity	P	Any process that modulates the frequency, rate or extent of a Type I restriction endodeoxyribonuclease activity.
32085	regulation of Type II site-specific deoxyribonuclease activity	P	Any process that modulates the frequency, rate or extent of a Type II restriction endodeoxyribonuclease activity.
32086	regulation of Type III site-specific deoxyribonuclease activity	P	Any process that modulates the frequency, rate or extent of a Type III restriction endodeoxyribonuclease activity.
32087	regulation of Type IV site-specific deoxyribonuclease activity	P	Any process that modulates the frequency, rate or extent of a Type IV restriction endodeoxyribonuclease activity.
32088	negative regulation of NF-kappaB transcription factor activity	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of the transcription factor NF-kappaB.
32089	NACHT domain binding	F	Interacting selectively and non-covalently with a NACHT (NAIP, CIITA, HET-E and TP1) domain. The NACHT domain consists of seven distinct conserved motifs, including an ATP/GTPase specific P-loop, a Mg(2+)-binding site and five more specific motifs.
32090	Pyrin domain binding	F	Interacting selectively and non-covalently with a Pyrin (PAAD/DAPIN) domain, a protein-protein interaction domain that has the same fold as the Death domain.
32091	negative regulation of protein binding	P	Any process that stops, prevents, or reduces the frequency, rate or extent of protein binding.
32092	positive regulation of protein binding	P	Any process that activates or increases the frequency, rate or extent of protein binding.
32093	SAM domain binding	F	Interacting selectively and non-covalently with a SAM (Sterile Alpha Motif) domain, which is a 70-amino acid protein sequence that participates in protein-protein, protein-lipid, and protein-RNA interactions and is conserved from lower to higher eukaryotes.
32094	response to food	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a food stimulus; food is anything which, when taken into the body, serves to nourish or build up the tissues or to supply body heat.
32095	regulation of response to food	P	Any process that modulates the frequency, rate or extent of a response to a food stimulus.
32096	negative regulation of response to food	P	Any process that stops, prevents, or reduces the frequency, rate or extent of a response to a food stimulus.
32097	positive regulation of response to food	P	Any process that activates, maintains, or increases the rate of a response to a food stimulus.
32098	regulation of appetite	P	Any process which modulates appetite, the desire or physical craving for food.
32099	negative regulation of appetite	P	Any process that reduces appetite.
32100	positive regulation of appetite	P	Any process that increases appetite.
32101	regulation of response to external stimulus	P	Any process that modulates the frequency, rate or extent of a response to an external stimulus.
32102	negative regulation of response to external stimulus	P	Any process that stops, prevents, or reduces the frequency, rate or extent of a response to an external stimulus.
32103	positive regulation of response to external stimulus	P	Any process that activates, maintains or increases the rate of a response to an external stimulus.
32104	regulation of response to extracellular stimulus	P	Any process that modulates the frequency, rate or extent of a response to an extracellular stimulus.
32105	negative regulation of response to extracellular stimulus	P	Any process that stops, prevents, or reduces the frequency, rate or extent of a response to an extracellular stimulus.
32106	positive regulation of response to extracellular stimulus	P	Any process that activates, maintains or increases the rate of a response to an extracellular stimulus.
32107	regulation of response to nutrient levels	P	Any process that modulates the frequency, rate or extent of a response to nutrient levels.
32108	negative regulation of response to nutrient levels	P	Any process that stops, prevents, or reduces the frequency, rate or extent of a response to nutrient levels.
32109	positive regulation of response to nutrient levels	P	Any process that activates or increases the frequency, rate or extent of a response to nutrient levels.
32110	regulation of protein histidine kinase activity	P	Any process that modulates the frequency, rate or extent of protein histidine kinase activity.
32111	activation of protein histidine kinase activity	P	Any process that initiates the activity of an inactive protein histidine kinase.
32112	negative regulation of protein histidine kinase activity	P	Any process that stops, prevents, or reduces the frequency, rate or extent of protein histidine kinase activity.
32113	regulation of carbohydrate phosphatase activity	P	Any process that modulates the frequency, rate or extent of carbohydrate phosphatase activity, the catalysis of the hydrolysis of phosphate from a carbohydrate phosphate.
32114	regulation of glucose-6-phosphatase activity	P	Any process that modulates the frequency, rate or extent of glucose-6-phosphatase activity, the catalysis of the reaction: D-glucose 6-phosphate + H2O = D-glucose + phosphate.
32115	sorbose reductase activity	F	Catalysis of the reaction: D-glucitol + NADP(+) = L-sorbose + H(+) + NADPH. The reaction may occur, to a minor extent, in the reverse direction.
32116	SMC loading complex	C	A protein complex required for the loading of a structural maintenance of chromosome (SMC) complex, such as cohesin, condensin or SMC5/SMC6, onto DNA. Appears to be eukaryotically conserved.
32117	horsetail-astral microtubule array	C	An array of astral microtubules that emanates from the spindle pole body during meiosis and facilitates horsetail nuclear movement.
32118	horsetail-astral microtubule organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the horsetail-astral array, a structure of astral microtubules that emanates from the spindle pole body during meiosis.
32119	sequestering of zinc ion	P	The process of binding or confining zinc ions such that they are separated from other components of a biological system.
32120	ascospore-type prospore membrane assembly	P	The process in which the nascent membrane forms at the meiotic outer plaque and grows until closure occurs and forespores, or prospores, are formed.
32121	meiotic attachment of telomeric heterochromatin to spindle pole body	P	The meiotic cell cycle process in which physical connections are formed between telomeric heterochromatin and the spindle pole body, facilitating bouquet formation.
32122	oral apparatus organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the oral apparatus. The oral apparatus is a funnel-like structure used by the cell to collect food and channel it to the cytostome, characteristic of ciliate protozoans.
32123	deep fiber	C	Inward projections of the cytoskeletal structures of the oral apparatus, which form a fiber that extends past the cytostome into the cytoplasm.
32124	macronucleus organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the macronucleus.
32125	micronucleus organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the micronucleus.
32126	eisosome	C	A cell part that is composed of the eisosome membrane or MCC domain, a furrow-like plasma membrane sub-domain and associated integral transmembrane proteins, and the proteins (eisosome filaments) that form a scaffolding lattice on the cytoplasmic face. Eisosomes broadly affect overall plasma membrane organization.
32127	dense core granule membrane	C	The lipid bilayer surrounding a dense core granule.
32128	flocculation via extracellular polymer	P	Non-sexual aggregation of single-celled organisms mediated by polymers (polysaccharides, proteins, and/or nucleic acids) secreted into the extracellular environment.
32129	histone deacetylase activity (H3-K9 specific)	F	Catalysis of the reaction: histone H3 N6-acetyl-L-lysine (position 9) + H2O = histone H3 L-lysine (position 9) + acetate. This reaction represents the removal of an acetyl group from lysine at position 9 of the histone H3 protein.
32130	medial membrane band assembly	P	The assembly of a sterol-rich region of the plasma membrane at the cell surface overlying the contractile ring.
32131	alkylated DNA binding	F	Interacting selectively and non-covalently with alkylated residues in DNA.
32132	O6-alkylguanine-DNA binding	F	Interacting selectively and non-covalently with O6-alkylguanine adducts in DNA.
32133	chromosome passenger complex	C	A eukaryotically conserved protein complex that localizes to kinetochores in early mitosis, the spindle mid-zone in anaphase B and to the telophase midbody. It has been proposed that the passenger complex coordinates various events based on its location to different structures during the course of mitosis. Complex members include the BIR-domain-containing protein Survivin, Aurora kinase, INCENP and Borealin.
32135	DNA insertion or deletion binding	F	Interacting selectively and non-covalently with double-stranded DNA containing insertions or deletions.
32136	adenine/cytosine mispair binding	F	Interacting selectively and non-covalently with double-stranded DNA containing an A/C mispair.
32137	guanine/thymine mispair binding	F	Interacting selectively and non-covalently with double-stranded DNA containing a G/T mispair.
32138	single base insertion or deletion binding	F	Interacting selectively and non-covalently with double-stranded DNA containing a single base insertion or deletion.
32139	dinucleotide insertion or deletion binding	F	Interacting selectively and non-covalently with double-stranded DNA containing a dinucleotide insertion or deletion.
32140	single adenine insertion binding	F	Interacting selectively and non-covalently with double-stranded DNA containing a single adenine insertion or a deletion that results in an unpaired adenine.
32141	single cytosine insertion binding	F	Interacting selectively and non-covalently with double-stranded DNA containing a single cytosine insertion or a deletion that results in an unpaired cytosine.
32142	single guanine insertion binding	F	Interacting selectively and non-covalently with double-stranded DNA containing a single guanine insertion or a deletion that results in an unpaired guanine.
32143	single thymine insertion binding	F	Interacting selectively and non-covalently with double-stranded DNA containing a single thymine insertion or a deletion that results in an unpaired thymine.
32144	4-aminobutyrate transaminase complex	C	A homodimeric protein complex that possesses 4-aminobutyrate transaminase activity.
32145	succinate-semialdehyde dehydrogenase binding	F	Interacting selectively and non-covalently with succinate-semialdehyde dehydrogenase.
32146	ATPase-coupled thiosulfate transmembrane transporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + thiosulfate(out) = ADP + phosphate + thiosulfate(in).
32147	activation of protein kinase activity	P	Any process that initiates the activity of an inactive protein kinase.
32148	activation of protein kinase B activity	P	Any process that initiates the activity of the inactive enzyme protein kinase B.
32149	response to rhamnose	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a rhamnose stimulus.
32150	ubiquinone biosynthetic process from chorismate	P	The chemical reactions and pathways resulting in the formation of ubiquinone, beginning with the conversion of chorismate to 4-hydroxybenzoate.
32151	mitotic septin complex	C	A heterooligomeric septin complex that acts during mitotic cell division.
32152	meiotic septin complex	C	A heterooligomeric septin complex that acts during meiotic cell division.
32153	cell division site	C	The eventual plane of cell division (also known as cell cleavage or cytokinesis) in a dividing cell. In Eukaryotes, the cleavage apparatus, composed of septin structures and the actomyosin contractile ring, forms along this plane, and the mitotic, or meiotic, spindle is aligned perpendicular to the division plane. In bacteria, the cell division site is generally located at mid-cell and is the site at which the cytoskeletal structure, the Z-ring, assembles.
32154	cleavage furrow	C	The cleavage furrow is a plasma membrane invagination at the cell division site. The cleavage furrow begins as a shallow groove and eventually deepens to divide the cytoplasm.
32155	cell division site part	C	Any constituent part of the cell division plane, the eventual plane of cell division in a dividing cell.
32156	septin cytoskeleton	C	The part of the cytoskeleton (the internal framework of a cell) composed of septins and associated proteins. Includes septin cytoskeleton-associated complexes.
32157	prospore contractile ring	C	A contractile ring, i.e. a cytoskeletal structure composed of actin filaments and myosin, that forms beneath the plasma membrane of the prospore envelope in meiotic cells in preparation for completing cytokinesis.
32158	septin band	C	A diffuse ring composed of a series of septin bars that run parallel to the long axis of the cell. This type of septin structure has been observed in a number of locations associated with polarized grown and/or deposition of new membrane, but not with cytokinesis, such as at the shmoo (mating projection) neck, at the junction between the mother cell and the germ tube (hypha) of a fungal cell growing filamentously.
32159	septin cap	C	A faint structure formed of septins found at the leading edge of growth in germ tubes and hyphae in fungal cells growing filamentously. This cap of septins colocalizes with a region of the plasma membrane that is rich in ergosterol.
32160	septin filament array	C	Arrays of septin filaments, or bars, found in a series of filamentous structures. Such structures have been observed in the prospore membrane during spore formation in S. cerevisiae and in the chlamydospore membrane during chlamydospore formation in C. albicans.
32161	cleavage apparatus septin structure	C	Any of a series of structures composed of septins and septin-associated proteins localized to the cleavage plane which are involved in cytokinesis.
32162	mating projection septin band	C	A septin band, i.e. a diffuse ring composed of a series of septin bars running parallel to the long axis of the cell, located at the neck of a shmoo (mating projection).
32163	hyphal septin band	C	A septin band, i.e. a diffuse ring composed of a series of septin bars running parallel to the long axis of the cell, located at the junction between the mother cell and the germ tube (hypha) of a fungal cell growing filamentously.
32164	hyphal septin cap	C	A faint structure formed of septins found at the leading edge of growth in hyphae of fungal cells growing filamentously. This cap of septins colocalizes with a region of the plasma membrane that is rich in ergosterol.
32165	prospore septin filament array	C	Arrays of septin filaments, or bars, found in a series of filamentous structures; observed in the prospore membrane during spore formation.
32166	chlamydospore septin filament array	C	Arrays of septin filaments, or bars, found in a series of filamentous structures. Observed in the chlamydospore membrane during chlamydospore formation.
32168	hyphal septin ring	C	A tight ring-shaped structure that forms in the division plane within hyphae of filamentous fungi at sites where a septum will form; composed of septins as well as septin-associated proteins.
32169	prospore septin ring	C	A tight ring-shaped structure that forms in the division plane at the site of cytokinesis in a prospore; composed of septins as well as septin-associated proteins.
32170	pseudohyphal septin ring	C	A tight ring-shaped structure that forms in the division plane at the junction between the mother cell and a pseudohyphal projection; composed of septins as well as septin-associated proteins.
32171	germ tube septin cap	C	A faint structure formed of septins found at the leading edge of growth in germ tubes of fungal cells growing filamentously. This cap of septins colocalizes with a region of the plasma membrane that is rich in ergosterol.
32172	germ tube septin ring	C	A tight ring-shaped structure that forms in the division plane within the germ tube of filamentous fungi at sites where a septum will form; composed of septins as well as septin-associated proteins.
32173	septin collar	C	A tubular, hourglass-shaped structure composed of highly ordered arrays of septin filaments; in budding yeast cells, the septin collar forms from the initial septin ring by expanding into the daughter cell.
32174	cellular bud neck septin collar	C	A tubular structure with flared ends, shaped like an hourglass and composed of highly ordered arrays of septin filaments, that forms at the bud neck of a dividing cell. In S. cerevisiae, this structure is located at the bud neck throughout most of the cell cycle and the septins are fixed within the structure, not exchanging with soluble septins. This septin structure acts as a scaffold for other proteins that function at the bud neck.
32175	mating projection septin ring	C	A septin ring, i.e. a ring-shaped structure composed of septins and septin-associated proteins, located at the neck of a shmoo (mating projection). The septin ring in the neck of a shmoo may act as a barrier to localize mating factors in the shmoo tip.
32176	split septin rings	C	A pair of rings that flank the site of cell division, formed by splitting of the septin ring (or collar) prior to cytokinesis; this double ring structure is thought to trap proteins needed for cytokinesis or the formation of the new membrane or cell wall between the two septin rings. Split septin rings are known to occur in budding yeast cells and probably occur in other cell types as well.
32177	cellular bud neck split septin rings	C	Two separate septin rings that are formed from the septin collar at the time of cytokinesis in cells that divide by budding. These two rings are thought to delineate a special compartment in which factors involved in cytokinesis are concentrated.
32178	medial membrane band	C	A sterol-rich region of the plasma membrane which forms at the cell surface overlying the contractile ring and spreads into the invaginating plasma membrane surrounding the septum.
32179	germ tube	C	The slender tubular outgrowth first produced by most spores in germination.
32180	ubiquinone biosynthetic process from tyrosine	P	The chemical reactions and pathways resulting in the formation of ubiquinone, beginning with the conversion of tyrosine to 4-hydroxybenzoate.
32181	dinucleotide repeat insertion binding	F	Interacting selectively and non-covalently with double-stranded DNA containing a dinucleotide repeat insertion or a deletion resulting in unpaired dinucleotide repeats.
32182	ubiquitin-like protein binding	F	Interacting selectively and non-covalently with a small conjugating protein such as ubiquitin or a ubiquitin-like protein.
32183	SUMO binding	F	Interacting selectively and non-covalently with the small ubiquitin-like protein SUMO.
32184	SUMO polymer binding	F	Interacting selectively and non-covalently with a polymer of the small ubiquitin-like protein SUMO.
32185	septin cytoskeleton organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising septin complexes and their associated proteins.
32186	cellular bud neck septin ring organization	P	Control of the formation, spatial distribution, and breakdown of a septin ring located at the bud neck.
32187	actomyosin contractile ring localization	P	The process in which a contractile ring is assembled and/or maintained in a specific location, in the context of cytokinesis that takes place as part of a cell cycle.
32188	establishment of actomyosin contractile ring localization	P	The process in which a contractile ring is assembled in a specific location as part of a process of cell cycle cytokinesis.
32189	maintenance of actomyosin contractile ring localization	P	Any process in which an actomyosin contractile ring is maintained in a location and prevented from moving elsewhere.
32190	acrosin binding	F	Interacting selectively and non-covalently with acrosin, a protein that is found in the acrosomes of sperm and possesses protease and carbohydrate binding activities.
32193	ubiquinone biosynthetic process via 2-polyprenylphenol	P	The chemical reactions and pathways resulting in the formation of ubiquinone, via the intermediates 2-polyprenylphenol and 2-polyprenyl-6-hydroxyphenol.
32194	ubiquinone biosynthetic process via 3,4-dihydroxy-5-polyprenylbenzoate	P	The chemical reactions and pathways resulting in the formation of ubiquinone, via the intermediates 3,4-dihydroxy-5-polyprenylbenzoate and 3-methoxy-4-hydroxy-5-polyprenylbenzoate.
32195	post-lysosomal vacuole	C	A membrane-bounded intracellular vesicle formed late in the endocytic pathway when the pH in the vacuole becomes neutral prior to exocytosis.
32196	transposition	P	Any process involved in mediating the movement of discrete segments of DNA between nonhomologous sites.
32197	transposition, RNA-mediated	P	Any process involved in a type of transpositional recombination which occurs via an RNA intermediate.
32198	MITE transposition	P	Any process involved in the transposition of miniature inverted-repeat transposable elements (MITEs).
32199	reverse transcription involved in RNA-mediated transposition	P	The synthesis of DNA from an RNA transposon intermediate.
32200	telomere organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of telomeres, terminal regions of a linear chromosome that include the telomeric DNA repeats and associated proteins.
32201	telomere maintenance via semi-conservative replication	P	The process in which telomeric DNA is synthesized semi-conservatively by the conventional replication machinery and telomeric accessory factors as part of cell cycle DNA replication.
32202	telomere assembly	P	A cellular process that results in the aggregation, arrangement and bonding together of a set of components to form a telomere at a non-telomeric double-stranded DNA end. A telomere is a terminal region of a linear chromosome that includes telomeric DNA repeats and associated proteins.
32203	telomere formation via telomerase	P	A cellular process that results in the formation of a telomere at a non-telomeric double-stranded DNA end that involves the activity of a telomerase enzyme.
32204	regulation of telomere maintenance	P	Any process that modulates the frequency, rate or extent of a process that affects and monitors the activity of telomeric proteins and the length of telomeric DNA.
32205	negative regulation of telomere maintenance	P	Any process that stops, prevents, or reduces the frequency, rate or extent of a process that affects and monitors the activity of telomeric proteins and the length of telomeric DNA.
32206	positive regulation of telomere maintenance	P	Any process that activates or increases the frequency, rate or extent of a process that affects and monitors the activity of telomeric proteins and the length of telomeric DNA.
32207	regulation of telomere maintenance via recombination	P	Any process that modulates the frequency, rate or extent of a recombinational process involved in the maintenance of proper telomeric length.
32208	negative regulation of telomere maintenance via recombination	P	Any process that stops, prevents, or reduces the frequency, rate or extent of a recombinational process involved in the maintenance of proper telomeric length.
32209	positive regulation of telomere maintenance via recombination	P	Any process that activates or increases the frequency, rate or extent of a recombinational process involved in the maintenance of proper telomeric length.
32210	regulation of telomere maintenance via telomerase	P	Any process that modulates the frequency, rate or extent of the addition of telomeric repeats by telomerase.
32211	negative regulation of telomere maintenance via telomerase	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the addition of telomeric repeats by telomerase.
32212	positive regulation of telomere maintenance via telomerase	P	Any process that activates or increases the frequency, rate or extent of the addition of telomeric repeats by telomerase.
32213	regulation of telomere maintenance via semi-conservative replication	P	Any process that modulates the frequency, rate or extent of the semi-conservative replication of telomeric DNA.
32214	negative regulation of telomere maintenance via semi-conservative replication	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the semi-conservative replication of telomeric DNA.
32215	positive regulation of telomere maintenance via semi-conservative replication	P	Any process that activates or increases the frequency, rate or extent of the semi-conservative replication of telomeric DNA.
32216	glucosaminyl-phosphotidylinositol O-acyltransferase activity	F	Catalysis of the reaction: glucosaminyl-phosphotidylinositol + fatty acyl-CoA = glucosaminyl-acyl-phosphotidylinositol + CoA.
32217	riboflavin transporter activity	F	Enables the directed movement of riboflavin into, out of or within a cell, or between cells. Riboflavin (vitamin B2) is a water-soluble B-complex vitamin, converted in the cell to FMN and FAD, cofactors required for the function of flavoproteins.
32218	riboflavin transport	P	The directed movement of riboflavin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Riboflavin (vitamin B2) is a water-soluble B-complex vitamin, converted in the cell to FMN and FAD, cofactors required for the function of flavoproteins.
32219	cell wall macromolecule catabolic process involved in cytogamy	P	The chemical reactions and pathways resulting in the breakdown of macromolecules forming part of a cell wall that contribute to cytogamy.
32220	plasma membrane fusion involved in cytogamy	P	The joining of two or more lipid bilayer membranes that surround cells, that contributes to cytogamy.
32221	Rpd3S complex	C	A eukaryotically conserved histone deacetylase complex which deacetylates histones preferentially in promoter regions. Composed of a catalytic histone deacetylase subunit, a chromodomain protein, a SIN3 family co-repressor, and a WD repeat protein (Clr6p, Alp13p, Pst2p, and Prw1p respectively in Schizosaccharomyces; Rpd3p, Sin3p, Ume1p, Rco1p and Eaf3 in Saccharomyces; homologs thereof in other species).
32222	regulation of synaptic transmission, cholinergic	P	Any process that modulates the frequency, rate or extent of cholinergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter acetylcholine.
32223	negative regulation of synaptic transmission, cholinergic	P	Any process that stops, prevents, or reduces the frequency, rate or extent of cholinergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter acetylcholine.
32224	positive regulation of synaptic transmission, cholinergic	P	Any process that activates, maintains or increases the frequency, rate or extent of cholinergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter acetylcholine.
32225	regulation of synaptic transmission, dopaminergic	P	Any process that modulates the frequency, rate or extent of dopaminergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter dopamine.
32226	positive regulation of synaptic transmission, dopaminergic	P	Any process that activates, maintains or increases the frequency, rate or extent of dopaminergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter dopamine.
32227	negative regulation of synaptic transmission, dopaminergic	P	Any process that stops, prevents, or reduces the frequency, rate or extent of dopaminergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter dopamine.
32228	regulation of synaptic transmission, GABAergic	P	Any process that modulates the frequency, rate or extent of GABAergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter gamma-aminobutyric acid (GABA).
32229	negative regulation of synaptic transmission, GABAergic	P	Any process that stops, prevents, or reduces the frequency, rate or extent of GABAergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter gamma-aminobutyric acid (GABA).
32230	positive regulation of synaptic transmission, GABAergic	P	Any process that activates, maintains or increases the frequency, rate or extent of GABAergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter gamma-aminobutyric acid (GABA).
32231	regulation of actin filament bundle assembly	P	Any process that modulates the frequency, rate or extent of the assembly of actin filament bundles.
32232	negative regulation of actin filament bundle assembly	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the assembly of actin filament bundles.
32233	positive regulation of actin filament bundle assembly	P	Any process that activates or increases the frequency, rate or extent of the assembly of actin filament bundles.
32237	activation of store-operated calcium channel activity	P	A process that initiates the activity of an inactive store-operated calcium channel.
32238	adenosine transport	P	The directed movement of adenosine, adenine riboside, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
32239	regulation of nucleobase-containing compound transport	P	Any process that modulates the frequency, rate or extent of the directed movement of nucleobases, nucleosides, nucleotides and nucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
32240	negative regulation of nucleobase-containing compound transport	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of nucleobases, nucleosides, nucleotides and nucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
32241	positive regulation of nucleobase-containing compound transport	P	Any process that activates or increases the frequency, rate or extent of the directed movement of nucleobases, nucleosides, nucleotides and nucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
32242	regulation of nucleoside transport	P	Any process that modulates the frequency, rate or extent of the directed movement of a nucleoside into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
32243	negative regulation of nucleoside transport	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a nucleoside into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
32244	positive regulation of nucleoside transport	P	Any process that activates or increases the frequency, rate or extent of the directed movement of a nucleoside into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
32245	regulation of purine nucleoside transport	P	Any process that modulates the frequency, rate or extent of the directed movement of a purine nucleoside into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
32246	regulation of pyrimidine nucleoside transport	P	Any process that modulates the frequency, rate or extent of the directed movement of a pyrimidine nucleoside into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
32247	negative regulation of purine nucleoside transport	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a purine nucleoside into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
32248	positive regulation of purine nucleoside transport	P	Any process that activates or increases the frequency, rate or extent of the directed movement of a purine nucleoside into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
32249	regulation of adenosine transport	P	Any process that modulates the frequency, rate or extent of the directed movement of adenosine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
32250	negative regulation of adenosine transport	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of adenosine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
32251	positive regulation of adenosine transport	P	Any process that activates or increases the frequency, rate or extent of the directed movement of adenosine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
32252	secretory granule localization	P	Any process in which a secretory granule is transported to, and/or maintained in, a specific location within the cell.
32253	dense core granule localization	P	Any process in which a dense core granule is transported to, and/or maintained in, a specific location within the cell.
32254	establishment of secretory granule localization	P	The directed movement of a secretory granule to a specific location.
32255	maintenance of secretory granule location	P	Any process in which a secretory granule is maintained in a specific location within a cell and prevented from moving elsewhere.
32256	establishment of dense core granule localization	P	The directed movement of a dense core granule to a specific location.
32257	maintenance of dense core granule location	P	Any process in which a dense core granule is maintained in a specific location within a cell and prevented from moving elsewhere.
32258	CVT pathway	P	A constitutive biosynthetic process that occurs under nutrient-rich conditions, in which two resident vacuolar hydrolases, aminopeptidase I and alpha-mannosidase, are sequestered into vesicles; these vesicles are transported to, and then fuse with, the vacuole. This pathway is mostly observed in yeast.
32259	methylation	P	The process in which a methyl group is covalently attached to a molecule.
32260	response to jasmonic acid stimulus involved in jasmonic acid and ethylene-dependent systemic resistance	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a jasmonic acid stimulus received in the context of the jasmonic acid- and ethylene (ethene)-dependent process that confers broad spectrum systemic resistance to disease in response to wounding or a pathogen.
32261	purine nucleotide salvage	P	Any process which produces a purine nucleotide from derivatives of it, without de novo synthesis.
32262	pyrimidine nucleotide salvage	P	Any process which produces a pyrimidine nucleotide from derivatives of it, without de novo synthesis.
32263	GMP salvage	P	Any process which produces guanosine monophosphate from derivatives of it, without de novo synthesis.
32264	IMP salvage	P	Any process which produces inosine monophosphate from derivatives of it, without de novo synthesis.
32265	XMP salvage	P	Any process which produces xanthosine monophosphate from derivatives of it, without de novo synthesis.
32266	phosphatidylinositol-3-phosphate binding	F	Interacting selectively and non-covalently with phosphatidylinositol-3-phosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 3' position.
32267	tRNA(Ile)-lysidine synthase activity	F	Catalysis of the ligation of lysine onto the cytidine residue present at the wobble position (usually position 34) of an AUA-specific isoleucine tRNA, to form the derivative lysidine. This modification converts both the codon specificity of tRNA(Ile) from AUG to AUA and its amino acid specificity from methionine to isoleucine.
32268	regulation of cellular protein metabolic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a protein, occurring at the level of an individual cell.
32269	negative regulation of cellular protein metabolic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving a protein, occurring at the level of an individual cell.
32270	positive regulation of cellular protein metabolic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving a protein, occurring at the level of an individual cell.
32271	regulation of protein polymerization	P	Any process that modulates the frequency, rate or extent of the process of creating protein polymers.
32272	negative regulation of protein polymerization	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the process of creating protein polymers.
32273	positive regulation of protein polymerization	P	Any process that activates or increases the frequency, rate or extent of the process of creating protein polymers.
32274	gonadotropin secretion	P	The regulated release of a gonadotropin, any hormone that stimulates the gonads, especially follicle-stimulating hormone and luteinizing hormone.
32275	luteinizing hormone secretion	P	The regulated release of luteinizing hormone, a gonadotropic glycoprotein hormone secreted by the anterior pituitary.
32276	regulation of gonadotropin secretion	P	Any process that modulates the frequency, rate or extent of the regulated release of a gonadotropin.
32277	negative regulation of gonadotropin secretion	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a gonadotropin.
32278	positive regulation of gonadotropin secretion	P	Any process that activates or increases the frequency, rate or extent of the regulated release of a gonadotropin.
32279	asymmetric synapse	C	A type of synapse occurring between an axon and a dendritic spine or dendritic shaft. Asymmetric synapses, the most abundant synapse type in the central nervous system, involve axons that contain predominantly spherical vesicles and contain a thickened postsynaptic density. Most or all synapses of this type are excitatory.
32280	symmetric synapse	C	A synapse that lacks an electron dense postsynaptic specialization. In vertebtrates, these occur primarily on dendrite shafts and neuronal cell bodies and involve persynapses containing clusters of predominantly flattened or elongated vesicles and are typcially inhibitory.
32281	AMPA glutamate receptor complex	C	An assembly of four or five subunits which form a structure with an extracellular N-terminus and a large loop that together form the ligand binding domain. The C-terminus is intracellular. The ionotropic glutamate receptor complex itself acts as a ligand gated ion channel; on binding glutamate, charged ions pass through a channel in the center of the receptor complex. The AMPA receptors mediate fast synaptic transmission in the CNS and are composed of subunits GluR1-4, products from separate genes. These subunits have an extracellular N-terminus and an intracellular C-terminus.
32282	plastid acetyl-CoA carboxylase complex	C	An acetyl-CoA carboxylase complex located in the stroma of a plastid.
32283	plastid acetate CoA-transferase complex	C	An acetate CoA-transferase complex located in the stroma of a plastid.
32284	plastid biotin carboxylase complex	C	A biotin carboxylase complex located in the stroma of a plastid.
32285	non-myelinated axon ensheathment	P	The process in which a non-myelinating glial cell membrane closes around an axon.
32286	central nervous system myelin maintenance	P	The process in which the structure and material content of mature central nervous system myelin is kept in a functional state.
32287	peripheral nervous system myelin maintenance	P	The process in which the structure and material content of mature peripheral nervous system myelin is kept in a functional state.
32288	myelin assembly	P	The process in which the wraps of cell membrane that constitute myelin are laid down around an axon in the central or peripheral nervous system.
32289	central nervous system myelin formation	P	The process in which the wraps of cell membrane that constitute myelin are laid down around an axon by an oligodendrocyte in the central nervous system.
32290	peripheral nervous system myelin formation	P	The process in which the wraps of cell membrane that constitute myelin are laid down around an axon by an oligodendrocyte in the peripheral nervous system.
32291	axon ensheathment in central nervous system	P	The process in which a glial cell membrane closes around an axon in the central nervous system. This can be a myelinating or a non-myelinating neuron-glial interaction.
32292	peripheral nervous system axon ensheathment	P	The process in which a Schwann cell membrane closes around an axon in the peripheral nervous system. This can be a myelinating or a non-myelinating neuron-glial interaction.
32293	non-myelinated axon ensheathment in central nervous system	P	The process in which a non-myelinating glial cell membrane encircles an axon in the central nervous system.
32294	peripheral nervous system non-myelinated axon ensheathment	P	The process in which a non-myelinating Schwann cell membrane encircles an axon in the peripheral nervous system. A single non-myelinating Schwann cell will typically associate with multiple axons.
32295	ensheathment of neuronal cell bodies	P	The process in which satellite glial cells isolate neuronal cell bodies.
32296	double-stranded RNA-specific ribonuclease activity	F	Catalysis of the hydrolysis of phosphodiester bonds in double-stranded RNA molecules.
32297	negative regulation of DNA-dependent DNA replication initiation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of initiation of DNA-dependent DNA replication.
32298	positive regulation of DNA-dependent DNA replication initiation	P	Any process that activates or increases the frequency, rate or extent of initiation of DNA-dependent DNA replication.
32299	ribonuclease H2 complex	C	A protein complex that possesses ribonuclease H activity, in which the catalytic subunit is a member of the RNase H2 (or HII) class. For example, in Saccharomyces the complex contains Rnh201p, Rnh202p and Rnh203p.
32300	mismatch repair complex	C	Any complex formed of proteins that act in mismatch repair.
32301	MutSalpha complex	C	A heterodimer involved in the recognition and repair of base-base and small insertion/deletion mismatches. In human the complex consists of two subunits, MSH2 and MSH6.
32302	MutSbeta complex	C	A heterodimer involved in binding to and correcting insertion/deletion mutations. In human the complex consists of two subunits, MSH2 and MSH3.
32303	regulation of icosanoid secretion	P	Any process that modulates the frequency, rate or extent of the controlled release of an icosanoid from a cell.
32304	negative regulation of icosanoid secretion	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of an icosanoid from a cell.
32305	positive regulation of icosanoid secretion	P	Any process that activates or increases the frequency, rate or extent of the controlled release of an icosanoid from a cell.
32306	regulation of prostaglandin secretion	P	Any process that modulates the frequency, rate or extent of the regulated release of a prostaglandin from a cell.
32307	negative regulation of prostaglandin secretion	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a prostaglandin from a cell.
32308	positive regulation of prostaglandin secretion	P	Any process that activates or increases the frequency, rate or extent of the regulated release of a prostaglandin from a cell.
32309	icosanoid secretion	P	The controlled release of icosanoids, any of a group of C20 polyunsaturated fatty acids from a cell or a tissue.
32310	prostaglandin secretion	P	The regulated release of a prostaglandin, any of a group of biologically active metabolites which contain a cyclopentane ring, from a cell or a tissue.
32311	angiogenin-PRI complex	C	A stable heterodimer of angiogenin and placental ribonuclease inhibitor; interaction between angiogenin and PRI prevents angiogenin binding to its receptor to stimulate angiogenesis.
32322	ubiquinone catabolic process	P	The chemical reactions and pathways resulting in the breakdown of ubiquinone, a lipid-soluble electron-transporting coenzyme.
32323	lipoate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of lipoate.
32324	molybdopterin cofactor biosynthetic process	P	The chemical reactions and pathways resulting in the formation of the molybdopterin cofactor (Moco), essential for the catalytic activity of some enzymes, e.g. sulfite oxidase, xanthine dehydrogenase, and aldehyde oxidase. The cofactor consists of a mononuclear molybdenum (Mo-molybdopterin) or tungsten ion (W-molybdopterin) coordinated by one or two molybdopterin ligands.
32325	molybdopterin cofactor catabolic process	P	The chemical reactions and pathways resulting in the breakdown of the molybdopterin cofactor (Moco), essential for the catalytic activity of some enzymes, e.g. sulfite oxidase, xanthine dehydrogenase, and aldehyde oxidase. The cofactor consists of a mononuclear molybdenum (Mo-molybdopterin) or tungsten ion (W-molybdopterin) coordinated by one or two molybdopterin ligands.
32326	Mo-molybdopterin cofactor catabolic process	P	The chemical reactions and pathways resulting in the breakdown of the Mo-molybdopterin cofactor, essential for the catalytic activity of some enzymes. The cofactor consists of a mononuclear molybdenum (Mo) ion coordinated by one or two molybdopterin ligands.
32327	W-molybdopterin cofactor catabolic process	P	The chemical reactions and pathways resulting in the breakdown of the W-molybdopterin cofactor, essential for the catalytic activity of some enzymes. The cofactor consists of a mononuclear tungsten ion (W) coordinated by one or two molybdopterin ligands.
32328	alanine transport	P	The directed movement of alanine, 2-aminopropanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
32329	serine transport	P	The directed movement of L-serine, 2-amino-3-hydroxypropanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
32330	regulation of chondrocyte differentiation	P	Any process that modulates the frequency, rate or extent of chondrocyte differentiation.
32331	negative regulation of chondrocyte differentiation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of chondrocyte differentiation.
32332	positive regulation of chondrocyte differentiation	P	Any process that activates or increases the frequency, rate or extent of chondrocyte differentiation.
32333	activin secretion	P	The regulated release of activin, a nonsteroidal regulator composed of two covalently linked beta subunits, which is synthesized in the pituitary gland and gonads and stimulates the secretion of follicle-stimulating hormone.
32334	inhibin secretion	P	The regulated release of an inhibin, either of two glycoproteins (designated A and B), secreted by the gonads and present in seminal plasma and follicular fluid, that inhibit pituitary production of follicle-stimulating hormone.
32335	regulation of activin secretion	P	Any process that modulates the frequency, rate or extent of the regulated release of activin from a cell.
32336	negative regulation of activin secretion	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of activin from a cell.
32337	positive regulation of activin secretion	P	Any process that activates or increases the frequency, rate or extent of the regulated release of activin from a cell.
32338	regulation of inhibin secretion	P	Any process that modulates the frequency, rate or extent of the regulated release of inhibin from a cell.
32339	negative regulation of inhibin secretion	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of inhibin from a cell.
32340	positive regulation of inhibin secretion	P	Any process that activates or increases the frequency, rate or extent of the regulated release of inhibin from a cell.
32341	aldosterone metabolic process	P	The chemical reactions and pathways involving aldosterone, a corticosteroid hormone that is produced by the zona glomerulosa of the adrenal cortex and regulates salt (sodium and potassium) and water balance.
32342	aldosterone biosynthetic process	P	The chemical reactions and pathways resulting in the formation of aldosterone, a corticosteroid hormone that is produced by the zona glomerulosa of the adrenal cortex and regulates salt (sodium and potassium) and water balance.
32343	aldosterone catabolic process	P	The chemical reactions and pathways resulting in the breakdown of aldosterone, a corticosteroid hormone that is produced by the zona glomerulosa of the adrenal cortex and regulates salt (sodium and potassium) and water balance.
32344	regulation of aldosterone metabolic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving aldosterone.
32345	negative regulation of aldosterone metabolic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving aldosterone.
32346	positive regulation of aldosterone metabolic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving aldosterone.
32347	regulation of aldosterone biosynthetic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of aldosterone.
32348	negative regulation of aldosterone biosynthetic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of aldosterone.
32349	positive regulation of aldosterone biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of aldosterone.
32350	regulation of hormone metabolic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving any hormone.
32351	negative regulation of hormone metabolic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving any hormone.
32352	positive regulation of hormone metabolic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving any hormone.
32353	negative regulation of hormone biosynthetic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of hormones.
32354	response to follicle-stimulating hormone	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a follicle-stimulating hormone stimulus.
32355	response to estradiol	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stimulus by estradiol, a C18 steroid hormone hydroxylated at C3 and C17 that acts as a potent estrogen.
32356	oxidized DNA binding	F	Interacting selectively and non-covalently with oxidized residues in DNA.
32357	oxidized purine DNA binding	F	Interacting selectively and non-covalently with oxidized purine residues in DNA.
32358	oxidized pyrimidine DNA binding	F	Interacting selectively and non-covalently with oxidized pyrimidine residues in DNA.
32359	provirus excision	P	The molecular events that lead to the excision of a viral genome from the host genome.
32361	pyridoxal phosphate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of pyridoxal phosphate, pyridoxal phosphorylated at the hydroxymethyl group of C-5, the active form of vitamin B6.
32363	FMN catabolic process	P	The chemical reactions and pathways resulting in the breakdown of FMN, riboflavin 5'-(dihydrogen phosphate), a coenzyme for a number of oxidative enzymes including NADH dehydrogenase.
32364	oxygen homeostasis	P	A homeostatic process involved in the maintenance of an internal steady state of oxygen within an organism or cell.
32365	intracellular lipid transport	P	The directed movement of lipids within cells.
32366	intracellular sterol transport	P	The directed movement of sterols within cells.
32367	intracellular cholesterol transport	P	The directed movement of cholesterol, cholest-5-en-3-beta-ol, within cells.
32368	regulation of lipid transport	P	Any process that modulates the frequency, rate or extent of the directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
32369	negative regulation of lipid transport	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
32370	positive regulation of lipid transport	P	Any process that activates or increases the frequency, rate or extent of the directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
32371	regulation of sterol transport	P	Any process that modulates the frequency, rate or extent of the directed movement of sterols into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
32372	negative regulation of sterol transport	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of sterols into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
32373	positive regulation of sterol transport	P	Any process that activates or increases the frequency, rate or extent of the directed movement of sterols into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
32374	regulation of cholesterol transport	P	Any process that modulates the frequency, rate or extent of the directed movement of cholesterol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
32375	negative regulation of cholesterol transport	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of cholesterol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
32376	positive regulation of cholesterol transport	P	Any process that activates or increases the frequency, rate or extent of the directed movement of cholesterol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
32377	regulation of intracellular lipid transport	P	Any process that modulates the frequency, rate or extent of the directed movement of lipids within cells.
32378	negative regulation of intracellular lipid transport	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of lipids within cells.
32379	positive regulation of intracellular lipid transport	P	Any process that activates or increases the frequency, rate or extent of the directed movement of lipids within cells.
32380	regulation of intracellular sterol transport	P	Any process that modulates the frequency, rate or extent of the directed movement of sterols within cells.
32381	negative regulation of intracellular sterol transport	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of sterols within cells.
32382	positive regulation of intracellular sterol transport	P	Any process that activates or increases the frequency, rate or extent of the directed movement of sterols within cells.
32383	regulation of intracellular cholesterol transport	P	Any process that modulates the frequency, rate or extent of the directed movement of cholesterol within cells.
32384	negative regulation of intracellular cholesterol transport	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of cholesterol within cells.
32385	positive regulation of intracellular cholesterol transport	P	Any process that activates or increases the frequency, rate or extent of the directed movement of cholesterol within cells.
32386	regulation of intracellular transport	P	Any process that modulates the frequency, rate or extent of the directed movement of substances within cells.
32387	negative regulation of intracellular transport	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of substances within cells.
32388	positive regulation of intracellular transport	P	Any process that activates or increases the frequency, rate or extent of the directed movement of substances within cells.
32389	MutLalpha complex	C	A heterodimer involved in the recognition of base-base and small insertion/deletion mismatches. In human the complex consists of two subunits, MLH1 and PMS2.
32390	MutLbeta complex	C	A heterodimer involved in the recognition of base-base and small insertion/deletion mismatches. In human the complex consists of two subunits, MLH1 and PMS1.
32391	photoreceptor connecting cilium	C	The portion of the photoreceptor cell cilium linking the photoreceptor inner and outer segments. It's considered to be equivalent to the ciliary transition zone.
32392	DNA geometric change	P	The process in which a transformation is induced in the geometry of a DNA double helix, resulting in a change in twist, writhe, or both, but with no change in linking number. Includes the unwinding of double-stranded DNA by helicases.
32393	MHC class I receptor activity	F	Combining with an MHC class I protein complex to initiate a change in cellular activity. Class I here refers to classical class I molecules.
32394	MHC class Ib receptor activity	F	Combining with an MHC class Ib protein complex and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. Class Ib here refers to non-classical class I molecules, such as those of the CD1 or HLA-E gene families.
32395	MHC class II receptor activity	F	Combining with an MHC class II protein complex and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
32396	inhibitory MHC class I receptor activity	F	Combining with a MHC class I protein complex to mediate signaling that inhibits activation of a lymphocyte.
32397	activating MHC class I receptor activity	F	Combining with a MHC class I protein complex to mediate signaling that activates a lymphocyte.
32398	MHC class Ib protein complex	C	A transmembrane protein complex composed of a MHC class Ib alpha chain and, in most cases, an invariant beta2-microglobin chain, and with or without a bound peptide or lipid antigen. Class Ib here refers to non-classical class I molecules, such as those of the CD1 or HLA-E gene families.
32399	HECT domain binding	F	Interacting selectively and non-covalently with a HECT, 'Homologous to the E6-AP Carboxyl Terminus', domain of a protein.
32400	melanosome localization	P	Any process in which a melanosome is transported to, and/or maintained in, a specific location within the cell.
32401	establishment of melanosome localization	P	The directed movement of a melanosome to a specific location.
32402	melanosome transport	P	The directed movement of melanosomes into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
32403	protein complex binding	F	Interacting selectively and non-covalently with any protein complex (a complex of two or more proteins that may include other nonprotein molecules).
32404	mismatch repair complex binding	F	Interacting selectively and non-covalently with a mismatch repair complex.
32405	MutLalpha complex binding	F	Interacting selectively and non-covalently with the mismatch repair complex MutLalpha.
32406	MutLbeta complex binding	F	Interacting selectively and non-covalently with the mismatch repair complex MutLbeta.
32407	MutSalpha complex binding	F	Interacting selectively and non-covalently with the mismatch repair complex MutSalpha.
32408	MutSbeta complex binding	F	Interacting selectively and non-covalently with the mismatch repair complex MutSbeta.
32409	regulation of transporter activity	P	Any process that modulates the activity of a transporter.
32410	negative regulation of transporter activity	P	Any process that stops or reduces the activity of a transporter.
32411	positive regulation of transporter activity	P	Any process that activates or increases the activity of a transporter.
32412	regulation of ion transmembrane transporter activity	P	Any process that modulates the activity of an ion transporter.
32413	negative regulation of ion transmembrane transporter activity	P	Any process that stops or reduces the activity of an ion transporter.
32414	positive regulation of ion transmembrane transporter activity	P	Any process that activates or increases the activity of an ion transporter.
32415	regulation of sodium:proton antiporter activity	P	Any process that modulates the activity of a sodium:hydrogen antiporter, which catalyzes the reaction: Na+(out) + H+(in) = Na+(in) + H+(out).
32416	negative regulation of sodium:proton antiporter activity	P	Any process that stops or reduces the activity of a sodium:hydrogen antiporter, which catalyzes the reaction: Na+(out) + H+(in) = Na+(in) + H+(out).
32417	positive regulation of sodium:proton antiporter activity	P	Any process that activates or increases the activity of a sodium:hydrogen antiporter, which catalyzes the reaction: Na+(out) + H+(in) = Na+(in) + H+(out).
32418	lysosome localization	P	Any process in which a lysosome is transported to, and/or maintained in, a specific location.
32419	extrinsic component of lysosome membrane	C	The component of an lysosome membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
32420	stereocilium	C	An actin-based protrusion from the apical surface of auditory and vestibular hair cells and of neuromast cells. These protrusions are supported by a bundle of cross-linked actin filaments (an actin cable), oriented such that the plus (barbed) ends are at the tip of the protrusion, capped by a tip complex which bridges to the plasma. Bundles of stereocilia act as mechanosensory organelles.
32421	stereocilium bundle	C	A bundle of cross-linked stereocilia, arranged around a kinocilium on the apical surface of a sensory hair cell (e.g. a neuromast, auditory or vestibular hair cell). Stereocilium bundles act as mechanosensory organelles by responding to fluid motion or fluid pressure changes.
32422	purine-rich negative regulatory element binding	F	Interacting selectively and non-covalently with a 30-bp purine-rich negative regulatory element; the best characterized such element is found in the first intronic region of the rat cardiac alpha-myosin heavy chain gene, and contains two palindromic high-affinity Ets-binding sites (CTTCCCTGGAAG). The presence of this element restricts expression of the gene containing it to cardiac myocytes.
32423	regulation of mismatch repair	P	Any process that modulates the frequency, rate or extent of mismatch repair.
32424	negative regulation of mismatch repair	P	Any process that stops, prevents, or reduces the frequency, rate or extent of mismatch repair.
32425	positive regulation of mismatch repair	P	Any process that activates or increases the frequency, rate or extent of mismatch repair.
32426	stereocilium tip	C	A distinct compartment at the tip of a stereocilium, distal to the site of attachment to the apical cell surface. It consists of a dense matrix bridging the barbed ends of the stereocilium actin filaments with the overlying plasma membrane.
32427	GBD domain binding	F	Interacting selectively and non-covalently with the GTPase protein binding domain (GDB) domain of a protein. The GBD is a short motif, including a minimum region of 16 amino acids, identified in proteins that bind to small GTPases such as Cdc42 and Rac.
32428	beta-N-acetylgalactosaminidase activity	F	Catalysis of the hydrolysis of terminal non-reducing N-acetyl-D-galactosamine residues in N-acetyl-beta-D-galactosaminides.
32429	regulation of phospholipase A2 activity	P	Any process that modulates the activity of the enzyme phospholipase A2.
32430	positive regulation of phospholipase A2 activity	P	Any process that activates or increases the activity of the enzyme phospholipase A2.
32431	activation of phospholipase A2 activity	P	Any process that initiates the activity of the inactive enzyme phospholipase A2.
32432	actin filament bundle	C	An assembly of actin filaments that are on the same axis but may be oriented with the same or opposite polarities and may be packed with different levels of tightness.
32433	filopodium tip	C	The end of a filopodium distal to the body of the cell.
32434	regulation of proteasomal ubiquitin-dependent protein catabolic process	P	Any process that modulates the frequency, rate or extent of the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome.
32435	negative regulation of proteasomal ubiquitin-dependent protein catabolic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome.
32436	positive regulation of proteasomal ubiquitin-dependent protein catabolic process	P	Any process that activates or increases the frequency, rate or extent of the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome.
32437	cuticular plate	C	A dense network of actin filaments found beneath the apical cell surface of hair cells, and into which stereocilia are inserted.
32438	melanosome organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a melanosome. A melanosome is a tissue-specific, membrane-bounded cytoplasmic organelle within which melanin pigments are synthesized and stored.
32439	endosome localization	P	Any process in which endosomes are transported to, and/or maintained in, a specific location within the cell.
32440	2-alkenal reductase [NAD(P)] activity	F	Catalysis of the reaction: n-alkanal + NAD(P)+ = alk-2-enal + NAD(P)H + H+.
32441	pheophorbide a oxygenase activity	F	Catalysis of the reaction: pheophorbide a + reduced ferredoxin + 2 O2 = red chlorophyll catabolite + oxidized ferredoxin + H2O.
32442	phenylcoumaran benzylic ether reductase activity	F	Catalysis of the NADPH-dependent 7-O-4' reduction of phenylcoumaran lignans to the corresponding diphenols; for example, catalysis of the reaction: dehydrodiconiferyl alcohol + NADPH + H+ = isodihydrodehydrodiconiferyl alcohol + NADP+.
32443	regulation of ergosterol biosynthetic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of ergosterol.
32444	activin responsive factor complex	C	A transcriptionally active complex that binds to an activin response element (ARE) in the promoter of target genes, and is composed of two SMAD2 proteins, one SMAD4 protein and a Forkhead activin signal transducer (FAST) transcription factor.
32445	fructose import	P	The directed movement of the hexose monosaccharide fructose into a cell or organelle.
32446	protein modification by small protein conjugation	P	A protein modification process in which one or more groups of a small protein, such as ubiquitin or a ubiquitin-like protein, are covalently attached to a target protein.
32447	protein urmylation	P	Covalent attachment of the ubiquitin-like protein URM1 to another protein.
32448	DNA hairpin binding	F	Interacting selectively and non-covalently with DNA containing a hairpin. A hairpin structure forms when a DNA strand folds back on itself and intrachain base pairing occurs between inverted repeat sequences.
32449	CBM complex	C	A protein complex comprising Carma1, Bcl10 and MALT1; plays a role in signal transduction during NF-kappaB activation.
32450	maltose alpha-glucosidase activity	F	Catalysis of the reaction: alpha-maltose + H2O = 2 alpha-D-glucose.
32451	demethylase activity	F	Catalysis of the removal of a methyl group from a substrate.
32452	histone demethylase activity	F	Catalysis of the removal of a methyl group from a histone.
32453	histone demethylase activity (H3-K4 specific)	F	Catalysis of the removal of a methyl group from lysine at position 4 of the histone H3 protein.
32454	histone demethylase activity (H3-K9 specific)	F	Catalysis of the reaction: histone H3 N6-methyl-L-lysine (position 9) + alpha-ketoglutarate + O2 = succinate + CO2 + formaldehyde + lysine. This reaction is the removal of a methyl group from lysine at position 9 of the histone H3 protein.
32455	nerve growth factor processing	P	The generation of a mature nerve growth factor (NGF) by proteolysis of a precursor.
32456	endocytic recycling	P	The directed movement of membrane-bounded vesicles from recycling endosomes back to the plasma membrane where they are recycled for further rounds of transport.
32457	fast endocytic recycling	P	The directed movement of membrane-bounded vesicles from peripheral endocytic compartments back to the plasma membrane where they are recycled for further rounds of transport.
32458	slow endocytic recycling	P	The directed movement of membrane-bounded vesicles from deep (non-peripheral) compartments endocytic compartments back to the plasma membrane where they are recycled for further rounds of transport.
32459	regulation of protein oligomerization	P	Any process that modulates the frequency, rate or extent of protein oligomerization.
32460	negative regulation of protein oligomerization	P	Any process that stops, prevents, or reduces the frequency, rate or extent of protein oligomerization.
32461	positive regulation of protein oligomerization	P	Any process that activates or increases the frequency, rate or extent of protein oligomerization.
32462	regulation of protein homooligomerization	P	Any process that modulates the frequency, rate or extent of protein homooligomerization.
32463	negative regulation of protein homooligomerization	P	Any process that stops, prevents, or reduces the frequency, rate or extent of protein homooligomerization.
32464	positive regulation of protein homooligomerization	P	Any process that activates or increases the frequency, rate or extent of protein homooligomerization.
32465	regulation of cytokinesis	P	Any process that modulates the frequency, rate or extent of the division of the cytoplasm of a cell and its separation into two daughter cells.
32466	negative regulation of cytokinesis	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the division of the cytoplasm of a cell, and its separation into two daughter cells.
32467	positive regulation of cytokinesis	P	Any process that activates or increases the frequency, rate or extent of the division of the cytoplasm of a cell, and its separation into two daughter cells.
32468	Golgi calcium ion homeostasis	P	Any process involved in the maintenance of an internal steady state of calcium ions within the Golgi apparatus of a cell or between the Golgi and its surroundings.
32469	endoplasmic reticulum calcium ion homeostasis	P	Any process involved in the maintenance of an internal steady state of calcium ions within the endoplasmic reticulum of a cell or between the endoplasmic reticulum and its surroundings.
32470	positive regulation of endoplasmic reticulum calcium ion concentration	P	Any process that increases the concentration of calcium ions in the endoplasmic reticulum.
32471	negative regulation of endoplasmic reticulum calcium ion concentration	P	Any process that decreases the concentration of calcium ions in the endoplasmic reticulum.
32472	Golgi calcium ion transport	P	The directed movement of calcium ions (Ca2+) into, out of or within the Golgi apparatus.
32473	cytoplasmic side of mitochondrial outer membrane	C	The external (cytoplasmic) face of the mitochondrial outer membrane.
32474	otolith morphogenesis	P	The process in which the anatomical structures of an otolith are generated and organized.
32475	otolith formation	P	The process that gives rise to an otolith. This process pertains to the initial formation of a structure from unspecified parts.
32476	decaprenyl diphosphate synthase complex	C	A complex that possesses di-trans,poly-cis-decaprenylcistransferase activity; involved in ubiquinone biosynthesis.
32477	homodimeric decaprenyl diphosphate synthase complex	C	A homodimeric complex that possesses di-trans,poly-cis-decaprenylcistransferase activity; involved in ubiquinone biosynthesis.
32478	heterotetrameric decaprenyl diphosphate synthase complex	C	A heterotetrameric complex located in the mitochondrial inner membrane that possesses di-trans,poly-cis-decaprenylcistransferase activity; involved in ubiquinone biosynthesis. In S. pombe it is a heterotetramer of Dlp1 and Dps1.
32479	regulation of type I interferon production	P	Any process that modulates the frequency, rate, or extent of interferon type I production. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families.
32480	negative regulation of type I interferon production	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of type I interferon production. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families.
32481	positive regulation of type I interferon production	P	Any process that activates or increases the frequency, rate, or extent of type I interferon production. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families.
32482	Rab protein signal transduction	P	A series of molecular signals within the cell that are mediated by a member of the Rab family of proteins switching to a GTP-bound active state.
32483	regulation of Rab protein signal transduction	P	Any process that modulates the frequency, rate or extent of Rab protein signal transduction.
32484	Ral protein signal transduction	P	A series of molecular signals within the cell that are mediated by a member of the Ral family of proteins switching to a GTP-bound active state.
32485	regulation of Ral protein signal transduction	P	Any process that modulates the frequency, rate or extent of Ral protein signal transduction.
32486	Rap protein signal transduction	P	A series of molecular signals within the cell that are mediated by a member of the Rap family of proteins switching to a GTP-bound active state.
32487	regulation of Rap protein signal transduction	P	Any process that modulates the frequency, rate or extent of Rap protein signal transduction.
32488	Cdc42 protein signal transduction	P	A series of molecular signals within the cell that are mediated by the Cdc42 protein switching to a GTP-bound active state.
32489	regulation of Cdc42 protein signal transduction	P	Any process that modulates the frequency, rate or extent of Cdc42 protein signal transduction.
32490	detection of molecule of bacterial origin	P	The series of events in which a stimulus from a molecule of bacterial origin is received and converted into a molecular signal.
32491	detection of molecule of fungal origin	P	The series of events in which a stimulus from a molecule of fungal origin is received and converted into a molecular signal.
32492	detection of molecule of oomycetes origin	P	The series of events in which a stimulus from a molecule of oomycetes origin is received and converted into a molecular signal.
32493	response to bacterial lipoprotein	P	Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bacterial lipoprotein stimulus.
32494	response to peptidoglycan	P	Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptidoglycan stimulus. Peptidoglycan is a bacterial cell wall macromolecule.
32495	response to muramyl dipeptide	P	Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a muramyl dipeptide stimulus. Muramyl dipeptide is derived from peptidoglycan.
32496	response to lipopolysaccharide	P	Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipopolysaccharide stimulus; lipopolysaccharide is a major component of the cell wall of gram-negative bacteria.
32497	detection of lipopolysaccharide	P	The series of events in which a lipopolysaccharide stimulus is received by a cell and converted into a molecular signal. Lipopolysaccharide is a major component of the cell wall of gram-negative bacteria.
32498	detection of muramyl dipeptide	P	The series of events in which a muramyl dipeptide stimulus is received by a cell and converted into a molecular signal. Muramyl dipeptide is derived from peptidoglycan.
32499	detection of peptidoglycan	P	The series of events in which a peptidoglycan stimulus is received by a cell and converted into a molecular signal. Peptidoglycan is a bacterial cell wall macromolecule.
32500	muramyl dipeptide binding	F	Interacting selectively and non-covalently, in a non-covalent manner, with muramyl dipeptide; muramyl dipeptide is derived from peptidoglycan.
32501	multicellular organismal process	P	Any biological process, occurring at the level of a multicellular organism, pertinent to its function.
32502	developmental process	P	A biological process whose specific outcome is the progression of an integrated living unit: an anatomical structure (which may be a subcellular structure, cell, tissue, or organ), or organism over time from an initial condition to a later condition.
32504	multicellular organism reproduction	P	The biological process in which new individuals are produced by one or two multicellular organisms. The new individuals inherit some proportion of their genetic material from the parent or parents.
32505	reproduction of a single-celled organism	P	The biological process in which new individuals are produced by one or two single-celled organisms. The new individuals inherit some proportion of their genetic material from the parent or parents.
32506	cytokinetic process	P	A cellular process that is involved in cytokinesis (the division of the cytoplasm of a cell and its separation into two daughter cells).
32507	maintenance of protein location in cell	P	Any process in which a protein is maintained in a specific location within, or in the membrane of, a cell, and is prevented from moving elsewhere.
32508	DNA duplex unwinding	P	The process in which interchain hydrogen bonds between two strands of DNA are broken or 'melted', generating a region of unpaired single strands.
32509	endosome transport via multivesicular body sorting pathway	P	The directed movement of substances from endosomes to lysosomes or vacuoles by a pathway in which molecules are sorted into multivesicular bodies, which then fuse with the target compartment.
32510	endosome to lysosome transport via multivesicular body sorting pathway	P	The directed movement of substances from endosomes to lysosomes by a pathway in which molecules are sorted into multivesicular bodies, which then fuse with the lysosome.
32511	late endosome to vacuole transport via multivesicular body sorting pathway	P	The directed movement of substances from endosomes to vacuoles by a pathway in which molecules are sorted into multivesicular bodies, which then fuse with the vacuole.
32512	regulation of protein phosphatase type 2B activity	P	Any process that modulates the activity of the enzyme protein phosphatase type 2B.
32513	negative regulation of protein phosphatase type 2B activity	P	Any process that stops or reduces the activity of the enzyme protein phosphatase type 2B.
32514	positive regulation of protein phosphatase type 2B activity	P	Any process that activates or increases the activity of the enzyme protein phosphatase type 2B.
32515	negative regulation of phosphoprotein phosphatase activity	P	Any process that stops or reduces the activity of a phosphoprotein phosphatase.
32516	positive regulation of phosphoprotein phosphatase activity	P	Any process that activates or increases the activity of a phosphoprotein phosphatase.
32517	SOD1-calcineurin complex	C	A protein complex formed by the association of superoxide dismutase 1 (SOD1) with calcineurin; complex formation is implicated in activation of calcineurin by SOD1.
32518	amino acid-exporting ATPase activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + amino acid(in) -> ADP + phosphate + amino acid(out).
32519	cysteine-exporting ATPase activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + cysteine(in) -> ADP + phosphate + cysteine(out).
32520	amino acid-importing ATPase activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + amino acid(out) -> ADP + phosphate + amino acid(in).
32521	D-methionine-exporting ATPase activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + D-methionine(in) -> ADP + phosphate + D-methionine(out).
32522	D-methionine-importing ATPase activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + D-methionine(out) -> ADP + phosphate + D-methionine(in).
32523	silicon efflux transmembrane transporter activity	F	Catalysis of the transfer of silicon from the inside of the cell to the outside of the cell across a membrane.
32525	somite rostral/caudal axis specification	P	The establishment, maintenance and elaboration of the rostro-caudal axis of a somite, prior to the morphological formation of a somite boundary.
32526	response to retinoic acid	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a retinoic acid stimulus.
32527	protein exit from endoplasmic reticulum	P	The directed movement of proteins from the endoplasmic reticulum.
32528	microvillus organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a microvillus, a thin cylindrical membrane-covered projection on the surface of a cell.
32529	follicle cell microvillus organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a microvillus on a follicle cell. A microvillus is a thin cylindrical membrane-covered projection on the surface of an animal cell containing a core bundle of actin filaments.
32530	regulation of microvillus organization	P	Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a microvillus.
32531	regulation of follicle cell microvillus organization	P	Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a microvillus on a follicle cell.
32532	regulation of microvillus length	P	A process that modulates the length of a microvillus.
32533	regulation of follicle cell microvillus length	P	A process that modulates the length of a microvillus on a follicle cell.
32534	regulation of microvillus assembly	P	A process that modulates the formation of a microvillus.
32535	regulation of cellular component size	P	A process that modulates the size of a cellular component.
32536	regulation of cell projection size	P	A process that modulates the size of a cell projection.
32537	host-seeking behavior	P	The specific behavior of an organism that are associated with finding a host organism; may include behavioral responses to light, temperature, or chemical emanations from the prospective host.
32538	regulation of host-seeking behavior	P	Any process that modulates the frequency, rate or extent of any behavior associated with finding a host organism.
32539	negative regulation of host-seeking behavior	P	Any process that stops, prevents, or reduces the frequency, rate or extent of any behavior associated with finding a host organism.
32540	positive regulation of host-seeking behavior	P	Any process that activates or increases the frequency, rate or extent of any behavior associated with finding a host organism.
32541	cortical endoplasmic reticulum	C	A cortical network of highly dynamic tubules that are juxtaposed to the plasma membrane and undergo ring closure and tubule-branching movements.
32542	sulfiredoxin activity	F	Catalysis of the reaction: peroxiredoxin-(S-hydroxy-S-oxocysteine) + ATP + 2 R-SH = peroxiredoxin-(S-hydroxycysteine) + ADP + phosphate + R-S-S-R.
32543	mitochondrial translation	P	The chemical reactions and pathways resulting in the formation of a protein in a mitochondrion. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein; the mitochondrion has its own ribosomes and transfer RNAs, and uses a genetic code that differs from the nuclear code.
32544	plastid translation	P	The chemical reactions and pathways resulting in the formation of a protein in a plastid. This is a ribosome-mediated process in which the information in messenger RNA (mRNA) is used to specify the sequence of amino acids in the protein; the plastid has its own ribosomes and transfer RNAs, and uses a genetic code that differs from the nuclear code.
32545	CURI complex	C	A protein complex that is involved in the transcription of ribosomal genes. In Saccharomyces this complex consists of Ckb2p, Utp22p, Rrp7p and Ifh1p.
32546	deoxyribonucleoside binding	F	Interacting selectively and non-covalently with a deoxyribonucleoside, a compound consisting of a purine or pyrimidine nitrogenous base linked to deoxyribose.
32547	purine deoxyribonucleoside binding	F	Interacting selectively and non-covalently with a purine deoxyribonucleoside, a compound consisting of a purine base linked to deoxyribose.
32548	pyrimidine deoxyribonucleoside binding	F	Interacting selectively and non-covalently with a pyrimidine deoxyribonucleoside, a compound consisting of a pyrimidine base linked to deoxyribose.
32549	ribonucleoside binding	F	Interacting selectively and non-covalently with a ribonucleoside, a compound consisting of a purine or pyrimidine nitrogenous base linked to ribose.
32550	purine ribonucleoside binding	F	Interacting selectively and non-covalently with a purine ribonucleoside, a compound consisting of a purine base linked to ribose.
32551	pyrimidine ribonucleoside binding	F	Interacting selectively and non-covalently with a pyrimidine ribonucleoside, a compound consisting of a pyrimidine base linked to ribose.
32552	deoxyribonucleotide binding	F	Interacting selectively and non-covalently with a deoxyribonucleotide, any compound consisting of a deoxyribonucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the deoxyribose moiety.
32553	ribonucleotide binding	F	Interacting selectively and non-covalently with a ribonucleotide, any compound consisting of a ribonucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose moiety.
32554	purine deoxyribonucleotide binding	F	Interacting selectively and non-covalently with a purine deoxyribonucleotide, any compound consisting of a purine deoxyribonucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the deoxyribose moiety.
32555	purine ribonucleotide binding	F	Interacting selectively and non-covalently with a purine ribonucleotide, any compound consisting of a purine ribonucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose moiety.
32556	pyrimidine deoxyribonucleotide binding	F	Interacting selectively and non-covalently with a pyrimidine deoxyribonucleotide, any compound consisting of a pyrimidine deoxyribonucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the deoxyribose moiety.
32557	pyrimidine ribonucleotide binding	F	Interacting selectively and non-covalently with a pyrimidine ribonucleotide, any compound consisting of a pyrimidine ribonucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose moiety.
32558	adenyl deoxyribonucleotide binding	F	Interacting selectively and non-covalently with an adenyl deoxyribonucleotide, any compound consisting of adenosine esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the deoxyribose moiety.
32559	adenyl ribonucleotide binding	F	Interacting selectively and non-covalently with an adenyl ribonucleotide, any compound consisting of adenosine esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose moiety.
32560	guanyl deoxyribonucleotide binding	F	Interacting selectively and non-covalently with a guanyl deoxyribonucleotide, any compound consisting of guanosine esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the deoxyribose moiety.
32561	guanyl ribonucleotide binding	F	Interacting selectively and non-covalently with a guanyl ribonucleotide, any compound consisting of guanosine esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose moiety.
32562	dAMP binding	F	Interacting selectively and non-covalently with dAMP, deoxyadenosine monophosphate.
32563	dADP binding	F	Interacting selectively and non-covalently with dADP, deoxyadenosine diphosphate.
32564	dATP binding	F	Interacting selectively and non-covalently with dATP, deoxyadenosine triphosphate.
32565	dGMP binding	F	Interacting selectively and non-covalently with dGMP, deoxyguanosine monophosphate.
32566	dGDP binding	F	Interacting selectively and non-covalently with dGDP, deoxyguanosine diphosphate.
32567	dGTP binding	F	Interacting selectively and non-covalently with dGTP, deoxyguanosine triphosphate.
32570	response to progesterone	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a progesterone stimulus.
32571	response to vitamin K	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin K stimulus.
32572	response to menaquinone	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a menaquinone (vitamin K2) stimulus.
32573	response to phylloquinone	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a phylloquinone (vitamin K1) stimulus.
32574	5'-3' RNA helicase activity	F	Catalysis of the unwinding of an RNA helix in the direction 5' to 3'.
32575	ATP-dependent 5'-3' RNA helicase activity	F	Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction drives the unwinding of an RNA helix in the direction 5' to 3'.
32576	O-linoleoyltransferase activity	F	Catalysis of the transfer of a linoleoyl ((9Z,12Z)-octadeca-9,12-dienoyl) group to an oxygen atom on the acceptor molecule.
32577	phosphatidylcholine:cardiolipin O-linoleoyltransferase activity	F	Catalysis of the transfer of a linoleoyl ((9Z,12Z)-octadeca-9,12-dienoyl) group from phosphatidylcholine to an oxygen atom on a cardiolipin molecule.
32578	aleurone grain membrane	C	The lipid bilayer surrounding an aleurone grain.
32579	apical lamina of hyaline layer	C	A fibrous network that is part of the hyalin layer extracellular matrix. The apical lamina is thought to be principally composed of the glycoproteins fibropellins. This matrix has been found in echinoderms.
32580	Golgi cisterna membrane	C	The lipid bilayer surrounding any of the thin, flattened compartments that form the central portion of the Golgi complex.
32581	ER-dependent peroxisome organization	P	A process of peroxisome organization in which assembly or arrangement of constituent parts takes place in the endoplasmic reticulum.
32584	growth cone membrane	C	The portion of the plasma membrane surrounding a growth cone.
32585	multivesicular body membrane	C	The lipid bilayer surrounding a multivesicular body.
32586	protein storage vacuole membrane	C	The lipid bilayer surrounding a protein storage vacuole.
32587	ruffle membrane	C	The portion of the plasma membrane surrounding a ruffle.
32588	trans-Golgi network membrane	C	The lipid bilayer surrounding any of the compartments that make up the trans-Golgi network.
32589	neuron projection membrane	C	The portion of the plasma membrane surrounding a neuron projection.
32590	dendrite membrane	C	The portion of the plasma membrane surrounding a dendrite.
32591	dendritic spine membrane	C	The portion of the plasma membrane surrounding a dendritic spine.
32592	integral component of mitochondrial membrane	C	The component of the mitochondrial membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
32593	insulin-responsive compartment	C	A small membrane-bounded vesicle that releases its contents by exocytosis in response to insulin stimulation; the contents are enriched in GLUT4, IRAP and VAMP2.
32594	protein transport within lipid bilayer	P	The directed movement of a protein from one location to another within a lipid bilayer.
32595	B cell receptor transport within lipid bilayer	P	The directed movement of a B cell receptor within a lipid bilayer.
32596	protein transport into membrane raft	P	The directed movement of a protein into a membrane raft. Membrane rafts are small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes.
32597	B cell receptor transport into membrane raft	P	The directed movement of a B cell receptor into a membrane raft.
32598	B cell receptor transport into immunological synapse	P	The directed movement of a B cell receptor into an immunological synapse.
32599	protein transport out of membrane raft	P	The directed movement of a protein out of a membrane raft. Membrane rafts are small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes.
32600	chemokine receptor transport out of membrane raft	P	The directed movement of a chemokine receptor out of a membrane raft.
32601	connective tissue growth factor production	P	The appearance of connective tissue growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
32602	chemokine production	P	The appearance of a chemokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
32603	fractalkine production	P	The appearance of fractalkine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
32604	granulocyte macrophage colony-stimulating factor production	P	The appearance of granulocyte macrophage colony-stimulating factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
32605	hepatocyte growth factor production	P	The appearance of hepatocyte growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
32606	type I interferon production	P	The appearance of type I interferon due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families.
32607	interferon-alpha production	P	The appearance of interferon-alpha due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
32608	interferon-beta production	P	The appearance of interferon-beta due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
32609	interferon-gamma production	P	The appearance of interferon-gamma due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Interferon-gamma is also known as type II interferon.
32610	interleukin-1 alpha production	P	The appearance of interleukin-1 alpha due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
32611	interleukin-1 beta production	P	The appearance of interleukin-1 beta due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
32612	interleukin-1 production	P	The appearance of interleukin-1 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
32613	interleukin-10 production	P	The appearance of interleukin-10 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
32614	interleukin-11 production	P	The appearance of interleukin-11 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
32615	interleukin-12 production	P	The appearance of interleukin-12 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
32616	interleukin-13 production	P	The appearance of interleukin-13 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
32617	interleukin-14 production	P	The appearance of interleukin-14 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
32618	interleukin-15 production	P	The appearance of interleukin-15 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
32619	interleukin-16 production	P	The appearance of interleukin-16 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
32620	interleukin-17 production	P	The appearance of any member of the interleukin-17 family of cytokines due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
32621	interleukin-18 production	P	The appearance of interleukin-18 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
32622	interleukin-19 production	P	The appearance of interleukin-19 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
32623	interleukin-2 production	P	The appearance of interleukin-2 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
32624	interleukin-20 production	P	The appearance of interleukin-20 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
32625	interleukin-21 production	P	The appearance of interleukin-21 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
32626	interleukin-22 production	P	The appearance of interleukin-22 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
32627	interleukin-23 production	P	The appearance of interleukin-23 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
32628	interleukin-24 production	P	The appearance of interleukin-24 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
32629	interleukin-25 production	P	The appearance of interleukin-25 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
32630	interleukin-26 production	P	The appearance of interleukin-26 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
32631	interleukin-27 production	P	The appearance of interleukin-27 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
32632	interleukin-3 production	P	The appearance of interleukin-3 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
32633	interleukin-4 production	P	The appearance of interleukin-4 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
32634	interleukin-5 production	P	The appearance of interleukin-5 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
32635	interleukin-6 production	P	The appearance of interleukin-6 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
32636	interleukin-7 production	P	The appearance of interleukin-7 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
32637	interleukin-8 production	P	The appearance of interleukin-8 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
32638	interleukin-9 production	P	The appearance of interleukin-9 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
32639	TRAIL production	P	The appearance of TRAIL due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
32640	tumor necrosis factor production	P	The appearance of tumor necrosis factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
32641	lymphotoxin A production	P	The appearance of lymphotoxin A due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
32642	regulation of chemokine production	P	Any process that modulates the frequency, rate, or extent of chemokine production.
32643	regulation of connective tissue growth factor production	P	Any process that modulates the frequency, rate, or extent of connective tissue growth factor production.
32644	regulation of fractalkine production	P	Any process that modulates the frequency, rate, or extent of fractalkine production.
32645	regulation of granulocyte macrophage colony-stimulating factor production	P	Any process that modulates the frequency, rate, or extent of granulocyte macrophage colony-stimulating factor production.
32646	regulation of hepatocyte growth factor production	P	Any process that modulates the frequency, rate, or extent of hepatocyte growth factor production.
32647	regulation of interferon-alpha production	P	Any process that modulates the frequency, rate, or extent of interferon-alpha production.
32648	regulation of interferon-beta production	P	Any process that modulates the frequency, rate, or extent of interferon-beta production.
32649	regulation of interferon-gamma production	P	Any process that modulates the frequency, rate, or extent of interferon-gamma production. Interferon-gamma is also known as type II interferon.
32650	regulation of interleukin-1 alpha production	P	Any process that modulates the frequency, rate, or extent of interleukin-1 alpha production.
32651	regulation of interleukin-1 beta production	P	Any process that modulates the frequency, rate, or extent of interleukin-1 beta production.
32652	regulation of interleukin-1 production	P	Any process that modulates the frequency, rate, or extent of interleukin-1 production.
32653	regulation of interleukin-10 production	P	Any process that modulates the frequency, rate, or extent of interleukin-10 production.
32654	regulation of interleukin-11 production	P	Any process that modulates the frequency, rate, or extent of interleukin-11 production.
32655	regulation of interleukin-12 production	P	Any process that modulates the frequency, rate, or extent of interleukin-12 production.
32656	regulation of interleukin-13 production	P	Any process that modulates the frequency, rate, or extent of interleukin-13 production.
32657	regulation of interleukin-14 production	P	Any process that modulates the frequency, rate, or extent of interleukin-14 production.
32658	regulation of interleukin-15 production	P	Any process that modulates the frequency, rate, or extent of interleukin-15 production.
32659	regulation of interleukin-16 production	P	Any process that modulates the frequency, rate, or extent of interleukin-16 production.
32660	regulation of interleukin-17 production	P	Any process that modulates the frequency, rate, or extent of production of any member of the interleukin-17 family of cytokines.
32661	regulation of interleukin-18 production	P	Any process that modulates the frequency, rate, or extent of interleukin-18 production.
32662	regulation of interleukin-19 production	P	Any process that modulates the frequency, rate, or extent of interleukin-19 production.
32663	regulation of interleukin-2 production	P	Any process that modulates the frequency, rate, or extent of interleukin-2 production.
32664	regulation of interleukin-20 production	P	Any process that modulates the frequency, rate, or extent of interleukin-20 production.
32665	regulation of interleukin-21 production	P	Any process that modulates the frequency, rate, or extent of interleukin-21 production.
32666	regulation of interleukin-22 production	P	Any process that modulates the frequency, rate, or extent of interleukin-22 production.
32667	regulation of interleukin-23 production	P	Any process that modulates the frequency, rate, or extent of interleukin-23 production.
32668	regulation of interleukin-24 production	P	Any process that modulates the frequency, rate, or extent of interleukin-24 production.
32669	regulation of interleukin-25 production	P	Any process that modulates the frequency, rate, or extent of interleukin-25 production.
32670	regulation of interleukin-26 production	P	Any process that modulates the frequency, rate, or extent of interleukin-26 production.
32671	regulation of interleukin-27 production	P	Any process that modulates the frequency, rate, or extent of interleukin-27 production.
32672	regulation of interleukin-3 production	P	Any process that modulates the frequency, rate, or extent of interleukin-3 production.
32673	regulation of interleukin-4 production	P	Any process that modulates the frequency, rate, or extent of interleukin-4 production.
32674	regulation of interleukin-5 production	P	Any process that modulates the frequency, rate, or extent of interleukin-5 production.
32675	regulation of interleukin-6 production	P	Any process that modulates the frequency, rate, or extent of interleukin-6 production.
32676	regulation of interleukin-7 production	P	Any process that modulates the frequency, rate, or extent of interleukin-7 production.
32677	regulation of interleukin-8 production	P	Any process that modulates the frequency, rate, or extent of interleukin-8 production.
32678	regulation of interleukin-9 production	P	Any process that modulates the frequency, rate, or extent of interleukin-9 production.
32679	regulation of TRAIL production	P	Any process that modulates the frequency, rate, or extent of TRAIL production.
32680	regulation of tumor necrosis factor production	P	Any process that modulates the frequency, rate, or extent of tumor necrosis factor production.
32681	regulation of lymphotoxin A production	P	Any process that modulates the frequency, rate, or extent of lymphotoxin A production.
32682	negative regulation of chemokine production	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of chemokine production.
32683	negative regulation of connective tissue growth factor production	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of connective tissue growth factor production.
32684	negative regulation of fractalkine production	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of fractalkine production.
32685	negative regulation of granulocyte macrophage colony-stimulating factor production	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of granulocyte macrophage colony-stimulating factor production.
32686	negative regulation of hepatocyte growth factor production	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of hepatocyte growth factor production.
32687	negative regulation of interferon-alpha production	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of interferon-alpha production.
32688	negative regulation of interferon-beta production	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of interferon-beta production.
32689	negative regulation of interferon-gamma production	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of interferon-gamma production. Interferon-gamma is also known as type II interferon.
32690	negative regulation of interleukin-1 alpha production	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-1 alpha production.
32691	negative regulation of interleukin-1 beta production	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-1 beta production.
32692	negative regulation of interleukin-1 production	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-1 production.
32693	negative regulation of interleukin-10 production	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-10 production.
32694	negative regulation of interleukin-11 production	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-11 production.
32695	negative regulation of interleukin-12 production	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-12 production.
32696	negative regulation of interleukin-13 production	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-13 production.
32697	negative regulation of interleukin-14 production	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-14 production.
32698	negative regulation of interleukin-15 production	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-15 production.
32699	negative regulation of interleukin-16 production	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-16 production.
32700	negative regulation of interleukin-17 production	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of production of any member of the interleukin-17 family of cytokines.
32701	negative regulation of interleukin-18 production	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-18 production.
32702	negative regulation of interleukin-19 production	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-19 production.
32703	negative regulation of interleukin-2 production	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-2 production.
32704	negative regulation of interleukin-20 production	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-20 production.
32705	negative regulation of interleukin-21 production	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-21 production.
32706	negative regulation of interleukin-22 production	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-22 production.
32707	negative regulation of interleukin-23 production	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-23 production.
32708	negative regulation of interleukin-24 production	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-24 production.
32709	negative regulation of interleukin-25 production	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-25 production.
32710	negative regulation of interleukin-26 production	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-26 production.
32711	negative regulation of interleukin-27 production	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-27 production.
32712	negative regulation of interleukin-3 production	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-3 production.
32713	negative regulation of interleukin-4 production	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-4 production.
32714	negative regulation of interleukin-5 production	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-5 production.
32715	negative regulation of interleukin-6 production	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-6 production.
32716	negative regulation of interleukin-7 production	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-7 production.
32717	negative regulation of interleukin-8 production	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-8 production.
32718	negative regulation of interleukin-9 production	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-9 production.
32719	negative regulation of TRAIL production	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of TRAIL production.
32720	negative regulation of tumor necrosis factor production	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of tumor necrosis factor production.
32721	negative regulation of lymphotoxin A production	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of lymphotoxin A production.
32722	positive regulation of chemokine production	P	Any process that activates or increases the frequency, rate, or extent of chemokine production.
32723	positive regulation of connective tissue growth factor production	P	Any process that activates or increases the frequency, rate, or extent of connective tissue growth factor production.
32724	positive regulation of fractalkine production	P	Any process that activates or increases the frequency, rate, or extent of fractalkine production.
32725	positive regulation of granulocyte macrophage colony-stimulating factor production	P	Any process that activates or increases the frequency, rate, or extent of granulocyte macrophage colony-stimulating factor production.
32726	positive regulation of hepatocyte growth factor production	P	Any process that activates or increases the frequency, rate, or extent of hepatocyte growth factor production.
32727	positive regulation of interferon-alpha production	P	Any process that activates or increases the frequency, rate, or extent of interferon-alpha production.
32728	positive regulation of interferon-beta production	P	Any process that activates or increases the frequency, rate, or extent of interferon-beta production.
32729	positive regulation of interferon-gamma production	P	Any process that activates or increases the frequency, rate, or extent of interferon-gamma production. Interferon-gamma is also known as type II interferon.
32730	positive regulation of interleukin-1 alpha production	P	Any process that activates or increases the frequency, rate, or extent of interleukin-1 alpha production.
32731	positive regulation of interleukin-1 beta production	P	Any process that activates or increases the frequency, rate, or extent of interleukin-1 beta production.
32732	positive regulation of interleukin-1 production	P	Any process that activates or increases the frequency, rate, or extent of interleukin-1 production.
32733	positive regulation of interleukin-10 production	P	Any process that activates or increases the frequency, rate, or extent of interleukin-10 production.
32734	positive regulation of interleukin-11 production	P	Any process that activates or increases the frequency, rate, or extent of interleukin-11 production.
32735	positive regulation of interleukin-12 production	P	Any process that activates or increases the frequency, rate, or extent of interleukin-12 production.
32736	positive regulation of interleukin-13 production	P	Any process that activates or increases the frequency, rate, or extent of interleukin-13 production.
32737	positive regulation of interleukin-14 production	P	Any process that activates or increases the frequency, rate, or extent of interleukin-14 production.
32738	positive regulation of interleukin-15 production	P	Any process that activates or increases the frequency, rate, or extent of interleukin-15 production.
32739	positive regulation of interleukin-16 production	P	Any process that activates or increases the frequency, rate, or extent of interleukin-16 production.
32740	positive regulation of interleukin-17 production	P	Any process that activates or increases the frequency, rate, or extent of production of any member of the interleukin-17 family of cytokines.
32741	positive regulation of interleukin-18 production	P	Any process that activates or increases the frequency, rate, or extent of interleukin-18 production.
32742	positive regulation of interleukin-19 production	P	Any process that activates or increases the frequency, rate, or extent of interleukin-19 production.
32743	positive regulation of interleukin-2 production	P	Any process that activates or increases the frequency, rate, or extent of interleukin-2 production.
32744	positive regulation of interleukin-20 production	P	Any process that activates or increases the frequency, rate, or extent of interleukin-20 production.
32745	positive regulation of interleukin-21 production	P	Any process that activates or increases the frequency, rate, or extent of interleukin-21 production.
32746	positive regulation of interleukin-22 production	P	Any process that activates or increases the frequency, rate, or extent of interleukin-22 production.
32747	positive regulation of interleukin-23 production	P	Any process that activates or increases the frequency, rate, or extent of interleukin-23 production.
32748	positive regulation of interleukin-24 production	P	Any process that activates or increases the frequency, rate, or extent of interleukin-24 production.
32749	positive regulation of interleukin-25 production	P	Any process that activates or increases the frequency, rate, or extent of interleukin-25 production.
32750	positive regulation of interleukin-26 production	P	Any process that activates or increases the frequency, rate, or extent of interleukin-26 production.
32751	positive regulation of interleukin-27 production	P	Any process that activates or increases the frequency, rate, or extent of interleukin-27 production.
32752	positive regulation of interleukin-3 production	P	Any process that activates or increases the frequency, rate, or extent of interleukin-3 production.
32753	positive regulation of interleukin-4 production	P	Any process that activates or increases the frequency, rate, or extent of interleukin-4 production.
32754	positive regulation of interleukin-5 production	P	Any process that activates or increases the frequency, rate, or extent of interleukin-5 production.
32755	positive regulation of interleukin-6 production	P	Any process that activates or increases the frequency, rate, or extent of interleukin-6 production.
32756	positive regulation of interleukin-7 production	P	Any process that activates or increases the frequency, rate, or extent of interleukin-7 production.
32757	positive regulation of interleukin-8 production	P	Any process that activates or increases the frequency, rate, or extent of interleukin-8 production.
32758	positive regulation of interleukin-9 production	P	Any process that activates or increases the frequency, rate, or extent of interleukin-9 production.
32759	positive regulation of TRAIL production	P	Any process that activates or increases the frequency, rate, or extent of TRAIL production.
32760	positive regulation of tumor necrosis factor production	P	Any process that activates or increases the frequency, rate, or extent of tumor necrosis factor production.
32761	positive regulation of lymphotoxin A production	P	Any process that activates or increases the frequency, rate, or extent of lymphotoxin A production.
32762	mast cell cytokine production	P	Any process that contributes to cytokine production by a mast cell.
32763	regulation of mast cell cytokine production	P	Any process that modulates the frequency, rate, or extent of mast cell cytokine production.
32764	negative regulation of mast cell cytokine production	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of mast cell cytokine production.
32765	positive regulation of mast cell cytokine production	P	Any process that activates or increases the frequency, rate, or extent of mast cell cytokine production.
32766	NHE3/E3KARP/ACTN4 complex	C	A heterotrimeric protein complex formed by the association of NHE3, E3KARP and alpha-actinin upon an increase in calcium ion concentration; found in clusters localized on plasma membrane and in intracellular compartments.
32767	copper-dependent protein binding	F	Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules), in the presence of copper.
32768	regulation of monooxygenase activity	P	Any process that modulates the activity of a monooxygenase.
32769	negative regulation of monooxygenase activity	P	Any process that stops or reduces the activity of a monooxygenase.
32770	positive regulation of monooxygenase activity	P	Any process that activates or increases the activity of a monooxygenase.
32771	regulation of monophenol monooxygenase activity	P	Any process that modulates the activity of the enzyme monophenol monooxygenase. Monophenol monooxygenase catalyzes the reaction: L-tyrosine + L-DOPA + O2 = L-DOPA + DOPAquinone + H2O.
32772	negative regulation of monophenol monooxygenase activity	P	Any process that stops or reduces the activity of the enzyme monophenol monooxygenase. Monophenol monooxygenase catalyzes the reaction: L-tyrosine + L-DOPA + O2 = L-DOPA + DOPAquinone + H2O.
32773	positive regulation of monophenol monooxygenase activity	P	Any process that activates or increases the activity of the enzyme monophenol oxygenase. Monophenol monooxygenase catalyzes the reaction: L-tyrosine + L-DOPA + O2 = L-DOPA + DOPAquinone + H2O.
32774	RNA biosynthetic process	P	The chemical reactions and pathways resulting in the formation of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage. Includes polymerization of ribonucleotide monomers. Refers not only to transcription but also to e.g. viral RNA replication.
32775	DNA methylation on adenine	P	The covalent transfer of a methyl group to N-6 of adenine in a DNA molecule.
32776	DNA methylation on cytosine	P	The covalent transfer of a methyl group to C-5 or N-4 of cytosine in a DNA molecule.
32777	Piccolo NuA4 histone acetyltransferase complex	C	A heterotrimeric H4/H2A histone acetyltransferase complex with a substrate preference of chromatin over free histones. It contains a subset of the proteins found in the larger NuA4 histone acetyltransferase complex; for example, the S. cerevisiae complex contains Esa1p, Yng2p, and Epl1p.
32778	cobalt-transporting ATPase activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + cobalt(out) = ADP + phosphate + cobalt(in).
32780	negative regulation of ATPase activity	P	Any process that stops or reduces the rate of ATP hydrolysis by an ATPase.
32781	positive regulation of ATPase activity	P	Any process that activates or increases the rate of ATP hydrolysis by an ATPase.
32782	bile acid secretion	P	The regulated release of bile acid, composed of any of a group of steroid carboxylic acids occurring in bile, by a cell or a tissue.
32783	ELL-EAF complex	C	A heterodimeric protein complex that acts as an RNA polymerase II elongation factor; the complex is conserved from yeast to humans, and is present in S. pombe, but absent from S. cerevisiae.
32784	regulation of DNA-templated transcription, elongation	P	Any process that modulates the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides catalyzed by a DNA-dependent RNA polymerase.
32785	negative regulation of DNA-templated transcription, elongation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides catalyzed by a DNA-dependent RNA polymerase.
32786	positive regulation of DNA-templated transcription, elongation	P	Any process that activates or increases the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides catalyzed by a DNA-dependent RNA polymerase.
32787	monocarboxylic acid metabolic process	P	The chemical reactions and pathways involving monocarboxylic acids, any organic acid containing one carboxyl (COOH) group or anion (COO-).
32788	saturated monocarboxylic acid metabolic process	P	The chemical reactions and pathways involving saturated monocarboxylic acids, any organic acid containing one carboxyl (COOH) group or anion (COO-) and fully saturated C-C bonds.
32789	unsaturated monocarboxylic acid metabolic process	P	The chemical reactions and pathways involving unsaturated monocarboxylic acids, any organic acid containing one carboxyl (COOH) group or anion (COO-) and one or more unsaturated C-C bonds.
32790	ribosome disassembly	P	The disaggregation of a ribosome into its constituent components; includes the dissociation of ribosomal subunits.
32791	lead ion binding	F	Interacting selectively and non-covalently with lead (Pb) ions.
32792	negative regulation of CREB transcription factor activity	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of the transcription factor CREB.
32793	positive regulation of CREB transcription factor activity	P	Any process that activates or increases the frequency, rate or extent of activity of the transcription factor CREB.
32794	GTPase activating protein binding	F	Interacting selectively and non-covalently with a GTPase activating protein.
32795	heterotrimeric G-protein binding	F	Interacting selectively and non-covalently with a heterotrimeric G-protein.
32796	uropod organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a uropod, a rigid membrane projection with related cytoskeletal components at the trailing edge of a lymphocyte or other cell in the process of migrating or being activated.
32797	SMN complex	C	A protein complex that contains the survival motor neuron (SMN) protein and at least eight additional integral components, including the Gemin2-8 and Unrip proteins; the complex is found in the cytoplasm and in nuclear Gems, and is involved in spliceosomal snRNP assembly in the cytoplasm and in pre-mRNA splicing in the nucleus.
32798	Swi5-Sfr1 complex	C	A conserved DNA recombinase mediator complex that contains two Swi5 monomers and one Sfr1 monomer in Schizosaccharomyces, or orthologs thereof (e.g. Sae3p and Mei5p in Saccharomyces).
32799	low-density lipoprotein receptor particle metabolic process	P	The chemical reactions and pathways involving low-density lipoprotein receptors.
32800	receptor biosynthetic process	P	The chemical reactions and pathways resulting in the formation of a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.
32801	receptor catabolic process	P	The chemical reactions and pathways resulting in the breakdown of a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.
32802	low-density lipoprotein particle receptor catabolic process	P	The chemical reactions and pathways resulting in the breakdown of a low-density lipoprotein particle receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.
32803	regulation of low-density lipoprotein particle receptor catabolic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of low-density lipoprotein particle receptors.
32804	negative regulation of low-density lipoprotein particle receptor catabolic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of low-density lipoprotein receptors.
32805	positive regulation of low-density lipoprotein particle receptor catabolic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of low-density lipoprotein particle receptors.
32806	carboxy-terminal domain protein kinase complex	C	A protein complex that phosphorylates amino acid residues of RNA polymerase II C-terminal domain repeats; phosphorylation occurs mainly on Ser2 and Ser5.
32807	DNA ligase IV complex	C	A eukaryotically conserved protein complex that contains DNA ligase IV and is involved in DNA repair by non-homologous end joining; in addition to the ligase, the complex also contains XRCC4 or a homolog, e.g. Saccharomyces Lif1p.
32808	lacrimal gland development	P	The process whose specific outcome is the progression of the lacrimal gland over time, from its formation to the mature structure. The lacrimal gland produces secretions that lubricate and protect the cornea of the eye.
32809	neuronal cell body membrane	C	The plasma membrane of a neuron cell body - excludes the plasma membrane of cell projections such as axons and dendrites.
32810	sterol response element binding	F	Interacting selectively and non-covalently with the sterol response element (SRE), a nonpalindromic sequence found in the promoters of genes involved in lipid metabolism.
32811	negative regulation of epinephrine secretion	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of epinephrine.
32812	positive regulation of epinephrine secretion	P	Any process that activates or increases the frequency, rate or extent of the regulated release of epinephrine.
32813	tumor necrosis factor receptor superfamily binding	F	Interacting selectively and non-covalently with any member of the tumor necrosis factor receptor superfamily.
32814	regulation of natural killer cell activation	P	Any process that modulates the frequency, rate or extent of natural killer cell activation.
32815	negative regulation of natural killer cell activation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer cell activation.
32816	positive regulation of natural killer cell activation	P	Any process that activates or increases the frequency, rate or extent of natural killer cell activation.
32817	regulation of natural killer cell proliferation	P	Any process that modulates the frequency, rate or extent of natural killer cell proliferation.
32818	negative regulation of natural killer cell proliferation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer cell proliferation.
32819	positive regulation of natural killer cell proliferation	P	Any process that activates or increases the frequency, rate or extent of natural killer cell proliferation.
32820	regulation of natural killer cell proliferation involved in immune response	P	Any process that modulates the frequency, rate or extent of natural killer cell proliferation as part of an immune response.
32821	negative regulation of natural killer cell proliferation involved in immune response	P	Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer cell proliferation as part of an immune response.
32822	positive regulation of natural killer cell proliferation involved in immune response	P	Any process that activates or increases the frequency, rate or extent of natural killer cell proliferation as part of an immune response.
32823	regulation of natural killer cell differentiation	P	Any process that modulates the frequency, rate or extent of natural killer cell differentiation.
32824	negative regulation of natural killer cell differentiation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer cell differentiation.
32825	positive regulation of natural killer cell differentiation	P	Any process that activates or increases the frequency, rate or extent of natural killer cell differentiation.
32826	regulation of natural killer cell differentiation involved in immune response	P	Any process that modulates the frequency, rate or extent of natural killer cell differentiation as part of an immune response.
32827	negative regulation of natural killer cell differentiation involved in immune response	P	Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer cell differentiation as part of an immune response.
32828	positive regulation of natural killer cell differentiation involved in immune response	P	Any process that activates or increases the frequency, rate or extent of natural killer cell differentiation as part of an immune response.
32829	regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation	P	Any process that modulates the frequency, rate or extent of differentiation of CD4-positive, CD25-positive, alpha-beta regulatory T cells.
32830	negative regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of differentiation of CD4-positive, CD25-positive, alpha-beta regulatory T cells.
32831	positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation	P	Any process that activates or increases the frequency, rate or extent of differentiation of CD4-positive, CD25-positive, alpha-beta regulatory T cells.
32832	regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response	P	Any process that modulates the frequency, rate or extent of differentiation of CD4-positive, CD25-positive, alpha-beta regulatory T cells as part of an immune response.
32833	negative regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response	P	Any process that stops, prevents, or reduces the frequency, rate or extent of differentiation of CD4-positive, CD25-positive, alpha-beta regulatory T cells as part of an immune response.
32834	positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation involved in immune response	P	Any process that activates or increases the frequency, rate or extent of differentiation of CD4-positive, CD25-positive, alpha-beta regulatory T cells as part of an immune response.
32835	glomerulus development	P	The progression of the glomerulus over time from its initial formation until its mature state. The glomerulus is a capillary tuft which forms a close network with the visceral epithelium (podocytes) and the mesangium to form the filtration barrier and is surrounded by Bowman's capsule in nephrons of the vertebrate kidney. The glomerulus is part of the nephron and is restricted to one body segment.
32836	glomerular basement membrane development	P	The process whose specific outcome is the progression of the glomerular basement membrane over time, from its formation to the mature structure. The glomerular basement membrane is the basal laminal portion of the glomerulus which performs the actual filtration.
32837	distributive segregation	P	The cell cycle process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets during a normally chiasmate meiosis under the condition that chiasma have not occurred between a particular pair of homologs. Distributive segregation is a "backup" mechanism to ensure the segregation of homologs that have failed to cross over - either as a consequence of mutation or not, as, for example, the 4th chromosome of Drosophila melanogaster (which never exchanges, presumably due to its small size) - but nevertheless segregate normally.
32838	cell projection cytoplasm	C	All of the contents of a cell projection, excluding the plasma membrane surrounding the projection.
32839	dendrite cytoplasm	C	All of the contents of a dendrite, excluding the surrounding plasma membrane.
32840	intramolecular proline-rich ligand binding	F	Interacting selectively and non-covalently with a proline-rich region within the same polypeptide.
32841	calcitonin binding	F	Interacting selectively and non-covalently with calcitonin, a peptide hormone responsible for reducing serum calcium levels by inhibiting osteoclastic bone reabsorption and promoting renal calcium excretion. It is synthesized and released by the C cells of the thyroid.
32843	hydroperoxide reductase activity	F	Catalysis of the reaction: 2 RSH + ROOH = RSSR + ROH + H2O. This reaction is the thiol-dependent conversion of an organic hydroperoxide to the corresponding alcohol.
32844	regulation of homeostatic process	P	Any process that modulates the frequency, rate, or extent of a homeostatic process.
32845	negative regulation of homeostatic process	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of a homeostatic process.
32846	positive regulation of homeostatic process	P	Any process that activates or increases the frequency, rate, or extent of a homeostatic process.
32847	regulation of cellular pH reduction	P	Any process that modulates the frequency, rate, or extent of a process that reduces the internal pH of a cell.
32848	negative regulation of cellular pH reduction	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of a process that reduces the internal pH of a cell.
32849	positive regulation of cellular pH reduction	P	Any process that activates or increases the frequency, rate, or extent of a process that reduces the internal pH of a cell.
32865	ERMES complex	C	A protein complex that links the endoplasmic reticulum with mitochondria and may have a role in promoting exchange of calcium and phospholipids between the two organelles. The complex is also associated with actively replicating mitochondrial DNA nucleoids, and may further coordinate mitochondrial genome replication and membrane growth.
32866	D-xylose:NADP reductase activity	F	Catalysis of the reaction: D-xylitol + NADP+ = D-xylose + NADPH + H+.
32867	L-arabinose:NADP reductase activity	F	Catalysis of the reaction: L-arabitol + NADP+ = L-arabinose + NADPH + H+.
32868	response to insulin	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin stimulus. Insulin is a polypeptide hormone produced by the islets of Langerhans of the pancreas in mammals, and by the homologous organs of other organisms.
32869	cellular response to insulin stimulus	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin stimulus. Insulin is a polypeptide hormone produced by the islets of Langerhans of the pancreas in mammals, and by the homologous organs of other organisms.
32870	cellular response to hormone stimulus	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hormone stimulus.
32871	regulation of karyogamy	P	Any process that modulates the frequency, rate or extent of karyogamy, the creation of a single nucleus from multiple nuclei as a result of membrane fusion.
32872	regulation of stress-activated MAPK cascade	P	Any process that modulates the frequency, rate or extent of signal transduction mediated by the stress-activated MAPK cascade.
32873	negative regulation of stress-activated MAPK cascade	P	Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the stress-activated MAPK cascade.
32874	positive regulation of stress-activated MAPK cascade	P	Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the stress-activated MAPK cascade.
32875	regulation of DNA endoreduplication	P	Any process that modulates the frequency, rate or extent of DNA endoreduplication.
32876	negative regulation of DNA endoreduplication	P	Any process that stops, prevents, or reduces the frequency, rate or extent of DNA endoreduplication.
32877	positive regulation of DNA endoreduplication	P	Any process that activates or increases the frequency, rate or extent of DNA endoreduplication.
32878	regulation of establishment or maintenance of cell polarity	P	Any process that modulates the frequency, rate or extent of the specification, formation or maintenance of anisotropic intracellular organization or cell growth patterns.
32879	regulation of localization	P	Any process that modulates the frequency, rate or extent of any process in which a cell, a substance, or a cellular entity is transported to, or maintained in, a specific location.
32880	regulation of protein localization	P	Any process that modulates the frequency, rate or extent of any process in which a protein is transported to, or maintained in, a specific location.
32881	regulation of polysaccharide metabolic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving polysaccharides.
32882	regulation of chitin metabolic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving chitin.
32883	regulation of chitin biosynthetic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of chitin.
32884	regulation of cell wall chitin biosynthetic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cell wall chitin.
32885	regulation of polysaccharide biosynthetic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of polysaccharides.
32886	regulation of microtubule-based process	P	Any process that modulates the frequency, rate or extent of any cellular process that depends upon or alters the microtubule cytoskeleton.
32887	regulation of spindle elongation	P	Any process that modulates the frequency, rate or extent of the cell cycle process in which the distance is lengthened between poles of the spindle.
32888	regulation of mitotic spindle elongation	P	Any process that modulates the frequency, rate or extent of the cell cycle process in which the distance is lengthened between poles of the mitotic spindle.
32889	regulation of vacuole fusion, non-autophagic	P	Any process that modulates the frequency, rate or extent of the fusion of two vacuole membranes to form a single vacuole.
32890	regulation of organic acid transport	P	Any process that modulates the frequency, rate or extent of the directed movement of organic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
32891	negative regulation of organic acid transport	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of organic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
32892	positive regulation of organic acid transport	P	Any process that activates or increases the frequency, rate or extent of the directed movement of organic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
32893	regulation of gluconate transport	P	Any process that modulates the frequency, rate or extent of the directed movement of gluconate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
32894	negative regulation of gluconate transport	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of gluconate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
32895	positive regulation of gluconate transport	P	Any process that activates or increases the frequency, rate or extent of the directed movement of gluconate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
32896	palmitoyl-CoA 9-desaturase activity	F	Catalysis of the reaction: palmitoyl-CoA + AH2 + O2 = palmitoleic acid (16:1delta9) + A + 2 H2O.
32897	negative regulation of viral transcription	P	Any process that stops, prevents, or reduces the frequency, rate or extent of viral transcription.
32898	neurotrophin production	P	The appearance of a neurotrophin due to biosynthesis or secretion by cells in a neuron's target field, resulting in an increase in its intracellular or extracellular levels. A neurotrophin is any of a family of growth factors that prevent apoptosis in neurons and promote nerve growth.
32899	regulation of neurotrophin production	P	Any process that modulates the frequency, rate, or extent of production of a neurotrophin.
32900	negative regulation of neurotrophin production	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of production of a neurotrophin.
32901	positive regulation of neurotrophin production	P	Any process that activates or increases the frequency, rate, or extent of production of a neurotrophin.
32902	nerve growth factor production	P	The appearance of nerve growth factor (NGF) due to biosynthesis or secretion by cells in a neuron's target field, resulting in an increase in its intracellular or extracellular levels.
32903	regulation of nerve growth factor production	P	Any process that modulates the frequency, rate, or extent of production of nerve growth factor (NGF).
32904	negative regulation of nerve growth factor production	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of production of nerve growth factor (NGF).
32905	transforming growth factor beta1 production	P	The appearance of transforming growth factor-beta1 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
32906	transforming growth factor beta2 production	P	The appearance of transforming growth factor-beta2 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
32907	transforming growth factor beta3 production	P	The appearance of transforming growth factor-beta3 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
32908	regulation of transforming growth factor beta1 production	P	Any process that modulates the frequency, rate, or extent of production of transforming growth factor-beta1.
32909	regulation of transforming growth factor beta2 production	P	Any process that modulates the frequency, rate, or extent of production of transforming growth factor-beta2.
32910	regulation of transforming growth factor beta3 production	P	Any process that modulates the frequency, rate, or extent of production of transforming growth factor-beta3.
32911	negative regulation of transforming growth factor beta1 production	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of production of transforming growth factor-beta1.
32912	negative regulation of transforming growth factor beta2 production	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of production of transforming growth factor-beta2.
32913	negative regulation of transforming growth factor beta3 production	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of production of transforming growth factor-beta3.
32914	positive regulation of transforming growth factor beta1 production	P	Any process that activates or increases the frequency, rate, or extent of production of transforming growth factor-beta1.
32915	positive regulation of transforming growth factor beta2 production	P	Any process that activates or increases the frequency, rate, or extent of production of transforming growth factor-beta2.
32916	positive regulation of transforming growth factor beta3 production	P	Any process that activates or increases the frequency, rate, or extent of production of transforming growth factor-beta3.
32917	polyamine acetylation	P	The modification of polyamines by addition of acetyl groups.
32918	spermidine acetylation	P	The modification of spermidine by addition of acetyl groups.
32919	spermine acetylation	P	The modification of spermine by addition of acetyl groups.
32920	putrescine acetylation	P	The modification of putrescine by addition of acetyl groups.
32921	sarcosine oxidase complex	C	A complex consisting of 4 protein subunits as a heterotetramer, that possesses sarcosine oxidase activity.
32922	circadian regulation of gene expression	P	Any process that modulates the frequency, rate or extent of gene expression such that an expression pattern recurs with a regularity of approximately 24 hours.
32923	organic phosphonate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of phosphonates, any organic compound containing one or more C-PO(OH)2 or C-PO(OR)2 (with R=alkyl, aryl) groups. Synthesis of phosphonic acid itself, an inorganic compound without the biochemically relevant C-P bond, is not included.
32924	activin receptor signaling pathway	P	A series of molecular signals initiated by the binding of an extracellular ligand to an activin receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.
32925	regulation of activin receptor signaling pathway	P	Any process that modulates the frequency, rate or extent of the activity of any activin receptor signaling pathway.
32926	negative regulation of activin receptor signaling pathway	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of any activin receptor signaling pathway.
32927	positive regulation of activin receptor signaling pathway	P	Any process that activates or increases the frequency, rate or extent of the activity of any activin receptor signaling pathway.
32928	regulation of superoxide anion generation	P	Any process that modulates the frequency, rate or extent of enzymatic generation of superoxide by a cell.
32929	negative regulation of superoxide anion generation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of enzymatic generation of superoxide by a cell.
32930	positive regulation of superoxide anion generation	P	Any process that activates or increases the frequency, rate or extent of enzymatic generation of superoxide by a cell.
32931	histone acetyltransferase activity (H3-K56 specific)	F	Catalysis of the reaction: acetyl-CoA + histone H3 L-lysine (position 56) = CoA + histone H3 N6-acetyl-L-lysine (position 56).
32932	negative regulation of astral microtubule depolymerization	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the depolymerization of astral microtubules.
32933	SREBP signaling pathway	P	A series of molecular signals from the endoplasmic reticulum to the nucleus generated as a consequence of decreased levels of one or more sterols (and in some yeast, changes in oxygen levels) and which proceeds through activation of a sterol response element binding transcription factor (SREBP) to result in up-regulation of target gene transcription.
32934	sterol binding	F	Interacting selectively and non-covalently with a sterol, any steroid containing a hydroxy group in the 3 position, closely related to cholestan-3-ol.
32935	sterol sensor activity	F	Interacting selectively and non-covalently with and responding, e.g. by conformational change, to changes in the cellular level of a sterol.
32936	SREBP-SCAP complex	C	A protein complex formed by the association of sterol regulatory element binding protein (SREBP) and SREBP-cleavage-activating protein (SCAP) in the ER membrane; in the absence of sterols, the SREBP-SCAP complex is packaged into COPII vesicles and travels to the Golgi apparatus to be processed.
32937	SREBP-SCAP-Insig complex	C	A protein complex formed by the association of sterol regulatory element binding protein (SREBP), SREBP-cleavage-activating protein (SCAP), and an Insig protein (Insig-1 or Insig-2) in the ER membrane.
32938	negative regulation of translation in response to oxidative stress	P	Any process that stops, prevents, or reduces the frequency, rate or extent of translation as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
32939	positive regulation of translation in response to oxidative stress	P	Any process that activates or increases the frequency, rate or extent of translation as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
32940	secretion by cell	P	The controlled release of a substance by a cell.
32941	secretion by tissue	P	The controlled release of a substance by a tissue.
32942	inositol tetrakisphosphate 2-kinase activity	F	Catalysis of the reaction: 1D-myo-inositol tetrakisphosphate + ATP = 1D-myo-inositol pentakisphosphate (containing 2-phosphate) + ADP.
32943	mononuclear cell proliferation	P	The expansion of a mononuclear cell population by cell division. A mononuclear cell is a leukocyte with a single non-segmented nucleus in the mature form.
32944	regulation of mononuclear cell proliferation	P	Any process that modulates the frequency, rate or extent of mononuclear cell proliferation.
32945	negative regulation of mononuclear cell proliferation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of mononuclear cell proliferation.
32946	positive regulation of mononuclear cell proliferation	P	Any process that activates or increases the frequency, rate or extent of mononuclear cell proliferation.
32947	protein complex scaffold	F	A structural molecule activity that provides a physical support for the assembly of a multiprotein complex. The scaffold may or may not be part of the final complex.
32948	regulation of alpha-glucan metabolic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving alpha-glucans.
32949	regulation of alpha-glucan biosynthetic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways relusting in the formation of alpha-glucans.
32950	regulation of beta-glucan metabolic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving beta-glucans.
32951	regulation of beta-glucan biosynthetic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways relusting in the formation of beta-glucans.
32952	regulation of (1->3)-beta-D-glucan metabolic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving (1->3)-beta-D-glucans.
32953	regulation of (1->3)-beta-D-glucan biosynthetic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans.
32954	regulation of cytokinetic process	P	Any process that modulates the frequency, rate or extent of a cytokinetic process.
32955	regulation of barrier septum assembly	P	Any process that modulates the frequency, rate or extent of barrier septum formation. Barrier septum formation is the assembly and arrangement of a septum that spans the plasma membrane interface between progeny cells following cytokinesis.
32956	regulation of actin cytoskeleton organization	P	Any process that modulates the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins.
32957	inositol trisphosphate metabolic process	P	The chemical reactions and pathways involving myo-inositol phosphate, 1,2,3,4,5,6-cyclohexanehexol, with three phosphate groups attached.
32958	inositol phosphate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of an inositol phosphate, 1,2,3,4,5,6-cyclohexanehexol, with one or more phosphate groups attached.
32959	inositol trisphosphate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of inositol trisphosphate, 1,2,3,4,5,6-cyclohexanehexol, with three phosphate groups attached.
32960	regulation of inositol trisphosphate biosynthetic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of inositol trisphosphate.
32961	negative regulation of inositol trisphosphate biosynthetic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of inositol trisphosphate.
32962	positive regulation of inositol trisphosphate biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of inositol trisphosphate.
32963	collagen metabolic process	P	The chemical reactions and pathways involving collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. Collagen is highly enriched in glycine (some regions are 33% glycine) and proline, occurring predominantly as 3-hydroxyproline (about 20%).
32964	collagen biosynthetic process	P	The chemical reactions and pathways resulting in the formation of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals. Collagen is highly enriched in glycine (some regions are 33% glycine) and proline, occurring predominantly as 3-hydroxyproline (about 20%).
32965	regulation of collagen biosynthetic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals.
32966	negative regulation of collagen biosynthetic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals.
32967	positive regulation of collagen biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of collagen, any of a group of fibrous proteins of very high tensile strength that form the main component of connective tissue in animals.
32968	positive regulation of transcription elongation from RNA polymerase II promoter	P	Any process that activates or increases the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides, catalyzed by RNA polymerase II.
32969	endosomal scaffold complex	C	A protein complex that contains MAPKSP1 (MP1, Map2k1ip1) and ROBLD3 (p14, Mapbpip), is anchored to late endosomes, and is involved in selective activation of the ERK1 in ERK/MAPK signaling.
32970	regulation of actin filament-based process	P	Any process that modulates the frequency, rate or extent of any cellular process that depends upon or alters the actin cytoskeleton.
32971	regulation of muscle filament sliding	P	Any process that modulates the frequency, rate or extent of muscle filament sliding.
32972	regulation of muscle filament sliding speed	P	Any process that modulates the velocity of muscle filament sliding.
32973	amino acid export	P	The directed movement of amino acids out of a cell or organelle.
32974	amino acid transmembrane export from vacuole	P	The directed movement of amino acids out of the vacuole, across the vacuolar membrane.
32975	amino acid transmembrane import into vacuole	P	The directed movement of amino acids into the vacuole across the vacuolar membrane.
32976	release of matrix enzymes from mitochondria	P	The process in which enzymes, such as aspartate aminotransferase, are enabled to move from the mitochondrial matrix into the cytosol, as part of the apoptotic process.
32977	membrane insertase activity	F	Mediates the integration of proteins into a membrane from the inner side of the membrane. Membrane insertases are highly conserved and include the bacterial YidC family, the plant chloroplast Alb3 family, and the fungal and animal mitochondrial Oxa1/Cox18 family.
32978	protein insertion into membrane from inner side	P	The process in which a protein is incorporated into a lipid bilayer, e.g., the prokaryotic, mitochondrial, or chloroplast inner membrane, from the inner side.
32979	protein insertion into mitochondrial membrane from inner side	P	The process in which a protein is incorporated into the mitochondrial membrane from the inner side. This includes membrane insertion of newly synthesized mitochondrially-encoded proteins, and insertion of nuclear-encoded proteins after their import into the mitochondrial matrix.
32980	keratinocyte activation	P	A change in the morphology or behavior of a keratinocyte resulting from exposure to an activating factor such as a cellular or soluble ligand. Upon activation, keratinocytes become migratory and hyperproliferative, and produce growth factors and cytokines.
32981	mitochondrial respiratory chain complex I assembly	P	The aggregation, arrangement and bonding together of a set of components to form mitochondrial respiratory chain complex I.
32982	myosin filament	C	A protein complex containing myosin heavy chains, plus associated light chains and other proteins, in which the myosin heavy chains are arranged into a filament.
32983	kainate selective glutamate receptor complex	C	An assembly of four or five subunits which form a structure with an extracellular N-terminus and a large loop that together form the ligand binding domain. The C-terminus is intracellular. The ionotropic glutamate receptor complex itself acts as a ligand gated ion channel; on binding glutamate, charged ions pass through a channel in the center of the receptor complex. Kainate receptors are multimeric assemblies of GluK1-3 (also called GluR5-7), GluK4 (KA1) and GluK5 (KA2) subunits.
32984	macromolecular complex disassembly	P	The disaggregation of a macromolecular complex into its constituent components.
32985	protein-carbohydrate complex disassembly	P	The disaggregation of a protein-carbohydrate complex into its constituent components.
32986	protein-DNA complex disassembly	P	The disaggregation of a protein-DNA complex into its constituent components.
32987	protein-lipid complex disassembly	P	The disaggregation of a protein-lipid complex into its constituent components.
32988	ribonucleoprotein complex disassembly	P	The disaggregation of a protein-RNA complex into its constituent components.
32989	cellular component morphogenesis	P	The process in which cellular structures, including whole cells or cell parts, are generated and organized.
32990	cell part morphogenesis	P	The process in which the anatomical structures of a cell part are generated and organized.
32991	macromolecular complex	C	A stable assembly of two or more macromolecules, i.e. proteins, nucleic acids, carbohydrates or lipids, in which at least one component is a protein and the constituent parts function together.
32992	protein-carbohydrate complex	C	A macromolecular complex containing separate protein and carbohydrate molecules. Separate in this context means not covalently bound to each other.
32993	protein-DNA complex	C	A macromolecular complex containing both protein and DNA molecules.
32994	protein-lipid complex	C	A macromolecular complex containing separate protein and lipid molecules. Separate in this context means not covalently bound to each other.
32995	regulation of fungal-type cell wall biogenesis	P	Any process that modulates the process in which a cell wall is synthesized, aggregates, and bonds together. The fungal-type cell wall contains beta-glucan and may contain chitin.
32996	Bcl3-Bcl10 complex	C	A protein complex containing Bcl3 and Bcl10, which forms when Akt1 is activated by TNF-alpha to phosphorylate Bcl10; the Bcl3-Bcl10 complex is translocated to the nucleus.
32997	Fc receptor complex	C	A protein complex composed of a subunit or subunits capable of binding the Fc portion of an immunoglobulin with additional signaling components. The complex functions as a receptor for immunoglobulin.
32998	Fc-epsilon receptor I complex	C	A protein complex composed of an Fc-epsilon RI alpha chain and an Fc-epsilon RI gamma chain dimer with or without an Fc-episilon RI beta chain and additional signaling components. The complex functions primarily as an activating receptor for IgE.
32999	Fc-alpha receptor I complex	C	A protein complex composed of an Fc-alpha R alpha chain and an Fc-epsilon RI gamma chain dimer with or without additional signaling components. The complex functions primarily as an activating receptor for IgA.
33000	Fc-gamma receptor I complex	C	A protein complex composed of an Fc-gamma RI alpha chain and an Fc-epsilon RI gamma chain dimer with or without additional signaling components. The complex functions primarily as an activating receptor for IgG.
33001	Fc-gamma receptor III complex	C	A protein complex composed of an Fc-gamma RIII alpha chain and an Fc-epsilon RI gamma chain dimer with or without an Fc-epsilon RI beta chain and additional signaling components. The complex functions primarily as an activating receptor for IgG.
33002	muscle cell proliferation	P	The expansion of a muscle cell population by cell division.
33003	regulation of mast cell activation	P	Any process that modulates the frequency, rate, or extent of mast cell activation.
33004	negative regulation of mast cell activation	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of mast cell activation.
33005	positive regulation of mast cell activation	P	Any process that activates or increases the frequency, rate, or extent of mast cell activation.
33006	regulation of mast cell activation involved in immune response	P	Any process that modulates the frequency, rate, or extent of mast cell activation as part of an immune response.
33007	negative regulation of mast cell activation involved in immune response	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of mast cell activation as part of an immune response.
33008	positive regulation of mast cell activation involved in immune response	P	Any process that activates or increases the frequency, rate, or extent of mast cell activation as part of an immune response.
33009	nucleomorph	C	A small, vestigial nucleus found in some plastids that derive from a eukaryotic endosymbiont. Observed in chlorarachniophytes and cryptomonads, which acquired their plastids from a green and red alga respectively.
33010	paranodal junction	C	A highly specialized cell-cell junction found in vertebrates, which forms between a neuron and a glial cell, and has structural similarity to Drosophila septate junctions. It flanks the node of Ranvier in myelinated nerve and electrically isolates the myelinated from unmyelinated nerve segments and physically separates the voltage-gated sodium channels at the node from the cluster of potassium channels underneath the myelin sheath.
33011	perinuclear theca	C	A condensed cytoplasmic structure that covers the nucleus of mammalian spermatozoa except for a narrow zone around the insertion of the tail. It shows two distinct regions, a subacrosomal layer and, continuing caudally beyond the acrosomic system, the postacrosomal sheath. The perinuclear theca has been considered a cytoskeletal scaffold responsible for maintaining the overall architecture of the mature sperm head; however, recent studies indicate that the bulk of its constituent proteins are not traditional cytoskeletal proteins but rather a variety of cytosolic proteins.
33012	porosome	C	A permanent cup-shaped structure at the cell plasma membrane in secretory cells. Following a secretory stimulus, secretory vesicles transiently dock and fuse at the base of porosomes and release intravesicular contents dictated by the turgor pressure generated from the swelling of secretory vesicles.
33013	tetrapyrrole metabolic process	P	The chemical reactions and pathways involving tetrapyrroles, natural pigments containing four pyrrole rings joined by one-carbon units linking position 2 of one pyrrole ring to position 5 of the next.
33014	tetrapyrrole biosynthetic process	P	The chemical reactions and pathways leading to the formation of tetrapyrroles, natural pigments containing four pyrrole rings joined by one-carbon units linking position 2 of one pyrrole ring to position 5 of the next.
33015	tetrapyrrole catabolic process	P	The chemical reactions and pathways leading to the breakdown of tetrapyrroles, natural pigments containing four pyrrole rings joined by one-carbon units linking position 2 of one pyrrole ring to position 5 of the next.
33016	rhoptry membrane	C	The lipid bilayer surrounding a rhoptry.
33017	sarcoplasmic reticulum membrane	C	The lipid bilayer surrounding the sarcoplasmic reticulum.
33018	sarcoplasmic reticulum lumen	C	The volume enclosed by the membranes of the sarcoplasmic reticulum.
33019	5-hydroxyvalerate dehydrogenase activity	F	Catalysis of the reaction: 5-hydroxyvalerate + NAD+ = 5-oxovalerate + NADH.
33020	cyclopentanol metabolic process	P	The chemical reactions and pathways involving cyclopentanol.
33021	cyclopentanol biosynthetic process	P	The chemical reactions and pathways resulting in the formation of cyclopentanol.
33022	cyclopentanol catabolic process	P	The chemical reactions and pathways resulting in the breakdown of cyclopentanol.
33023	mast cell homeostasis	P	The process of regulating the proliferation and elimination of mast cells such that the total number of mast cells within a whole or part of an organism is stable over time in the absence of an outside stimulus.
33024	mast cell apoptotic process	P	Any apoptotic process in a mast cell, a cell that is found in almost all tissues containing numerous basophilic granules and capable of releasing large amounts of histamine and heparin upon activation.
33025	regulation of mast cell apoptotic process	P	Any process that modulates the frequency, rate, or extent of mast cell apoptotic process.
33026	negative regulation of mast cell apoptotic process	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of mast cell apoptotic process.
33027	positive regulation of mast cell apoptotic process	P	Any process that activates or increases the frequency, rate, or extent of mast cell apoptotic process.
33028	myeloid cell apoptotic process	P	Any apoptotic process in a myeloid cell, a cell of the monocyte, granulocyte, mast cell, megakaryocyte, or erythroid lineage.
33029	regulation of neutrophil apoptotic process	P	Any process that modulates the frequency, rate, or extent of neutrophil apoptotic process.
33030	negative regulation of neutrophil apoptotic process	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of neutrophil apoptotic process.
33031	positive regulation of neutrophil apoptotic process	P	Any process that activates or increases the frequency, rate, or extent of neutrophil apoptotic process.
33032	regulation of myeloid cell apoptotic process	P	Any process that modulates the frequency, rate, or extent of myeloid cell apoptotic process.
33033	negative regulation of myeloid cell apoptotic process	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of a myeloid cell apoptotic process.
33034	positive regulation of myeloid cell apoptotic process	P	Any process that activates or increases the frequency, rate, or extent of myeloid cell apoptotic process.
33036	macromolecule localization	P	Any process in which a macromolecule is transported to, or maintained in, a specific location.
33037	polysaccharide localization	P	Any process in which a polysaccharide is transported to, or maintained in, a specific location.
33038	bitter taste receptor activity	F	Combining with soluble bitter compounds to initiate a change in cell activity. These receptors are responsible for the sense of bitter taste.
33039	salty taste receptor activity	F	Combining with soluble salty compounds to initiate a change in cell activity. These receptors are responsible for the sense of salty taste.
33040	sour taste receptor activity	F	Combining with soluble sour compounds to initiate a change in cell activity. These receptors are responsible for the sense of sour taste.
33041	sweet taste receptor activity	F	Combining with soluble sweet compounds to initiate a change in cell activity. These receptors are responsible for the sense of sweet taste.
33042	umami taste receptor activity	F	Combining with soluble umami compounds to initiate a change in cell activity. These receptors are responsible for the sense of umami taste, the savory taste of meats and other foods that are rich in glutamates.
33043	regulation of organelle organization	P	Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of an organelle.
33044	regulation of chromosome organization	P	Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a chromosome.
33045	regulation of sister chromatid segregation	P	Any process that modulates the frequency, rate or extent of sister chromatid segregation.
33046	negative regulation of sister chromatid segregation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of sister chromatid segregation.
33047	regulation of mitotic sister chromatid segregation	P	Any process that modulates the frequency, rate or extent of sister chromatid segregation during mitosis.
33048	negative regulation of mitotic sister chromatid segregation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of sister chromatid segregation during mitosis.
33049	clavulanic acid metabolic process	P	The chemical reactions and pathways involving clavulanic acid, (2R,3Z,5R)-3-(2-hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo[3.2.0]heptane-2-carboxylic acid.
33050	clavulanic acid biosynthetic process	P	The chemical reactions and pathways resulting in the formation of clavulanic acid, (2R,3Z,5R)-3-(2-hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo[3.2.0]heptane-2-carboxylic acid.
33051	aminophosphonate metabolic process	P	The chemical reactions and pathways involving aminophosphonates, phosphonic acid derivatives that contain an amino group.
33052	cyanoamino acid metabolic process	P	The chemical reactions and pathways involving cyanoamino acids, amino acid derivatives that contain a cyanide group.
33053	D-glutamine metabolic process	P	The chemical reactions and pathways involving D-glutamine, the D-enantiomer of the amino acid glutamine, i.e. (2R)-2,5-diamino-5-oxopentanoic acid.
33054	D-glutamate metabolic process	P	The chemical reactions and pathways involving D-glutamate, the D-enantiomer of the amino acid glutamate, i.e. (2R)-2-aminopentanedioic acid.
33055	D-arginine metabolic process	P	The chemical reactions and pathways involving D-arginine, the D-enantiomer of the amino acid arginine, i.e. (2R)-2-amino-5-(carbamimidamido)pentanoic acid.
33056	D-ornithine metabolic process	P	The chemical reactions and pathways involving D-ornithine, the D-enantiomer of the amino acid ornithine, i.e. (2R)-2,5-diaminopentanoic acid.
33058	directional locomotion	P	Self-propelled movement of a cell or organism from one location to another along an axis.
33059	cellular pigmentation	P	The deposition or aggregation of coloring matter in a cell.
33060	ocellus pigmentation	P	The deposition or aggregation of coloring matter in an ocellus, a minute simple eye found in many invertebrates.
33061	DNA recombinase mediator complex	C	A protein complex containing accessory proteins which bind a recombinase (e.g. Rad51) and bind single-stranded DNA (ssDNA), and promote nucleation of the recombinase onto ssDNA.
33062	Rhp55-Rhp57 complex	C	A conserved heterodimeric DNA recombinase mediator complex that contains the RecA family proteins Rhp55p and Rph57 in Schizosaccharomyces, or orthologs thereof (e.g. Rad55p and Rad57p in Saccharomyces).
33063	Rad51B-Rad51C-Rad51D-XRCC2 complex	C	A DNA recombinase mediator complex that contains the Rad51 paralogs RAD51B, RAD51C, RAD51D, and XRCC2, or orthologs thereof.
33064	XRCC2-RAD51D complex	C	A heterodimeric DNA recombinase mediator complex that contains the Rad51 paralogs RAD51D and XRCC2, or orthologs thereof; conserved from fission yeast to human but absent from budding yeast.
33065	Rad51C-XRCC3 complex	C	A DNA recombinase mediator complex that contains the Rad51 paralogs RAD51C and XRCC3, or orthologs thereof.
33066	Rad51B-Rad51C complex	C	A DNA recombinase mediator complex that contains the Rad51 paralogs RAD51B and RAD51C, or orthologs thereof.
33067	macrolide metabolic process	P	The chemical reactions and pathways involving macrolides, any of a large group of polyketide compounds that contain a large lactone ring with few or no double bonds and no nitrogen atoms, linked glycosidically to one or more sugar groups. The macrolides include the carbomycins, the erythromycins, oleandomycin, oligomycins, and the spiramycins, and act as antibiotics, mainly against Gram-positive bacteria.
33068	macrolide biosynthetic process	P	The chemical reactions and pathways leading to the formation of macrolides, any of a large group of polyketide compounds that contain a large lactone ring with few or no double bonds and no nitrogen atoms, linked glycosidically to one or more sugar groups. The macrolides include the carbomycins, the erythromycins, oleandomycin, oligomycins, and the spiramycins, and act as antibiotics, mainly against Gram-positive bacteria.
33069	ansamycin metabolic process	P	The chemical reactions and pathways involving ansamycins, any of a group of complex macrolactam compounds characterized by a cyclic structure in which an aliphatic ansa chain forms a bridge between two non-adjacent positions of a cyclic p-system; many exhibit antibacterial, antifungal or antitumor activity.
33070	ansamycin biosynthetic process	P	The chemical reactions and pathways leading to the formation of ansamycins, any of a group of complex macrolactam compounds characterized by a cyclic structure in which an aliphatic ansa chain forms a bridge between two non-adjacent positions of a cyclic p-system; many exhibit antibacterial, antifungal or antitumor activity.
33071	vancomycin metabolic process	P	The chemical reactions and pathways involving vancomycin, (3S,6R,7R,11R,23S,26S,30aS,36R,38aR)-44-[2-O-(3-amino-2,3,6-trideoxy-3-C-methyl-alpha-L-lyxo-hexopyranosyl)-beta-D-glucopyranosyloxy]-3-(carbamoylmethyl)-10,19-dichloro-2,3,4,5,6,7,23,25,26,36,37,38,38a-tetradecahydro-7,22,28,30,32-pentahydroxy-6-(N-methyl-D-leucyl)-2,5,24,38,39-pentaoxo-1H,22H-23,36-(epiminomethano)-8,11:18,21-dietheno-13,16:31,35-di(metheno)[1,6,9]oxadiazacyclohexadecino[4,5-m][10,2,16]benzoxadiazacyclotetracosine-26-carboxylic acid, a complex glycopeptide from Streptomyces orientalis that inhibits a specific step in the synthesis of the peptidoglycan layer in Gram-positive bacteria.
33072	vancomycin biosynthetic process	P	The chemical reactions and pathways leading to the formation of vancomycin, (3S,6R,7R,11R,23S,26S,30aS,36R,38aR)-44-[2-O-(3-amino-2,3,6-trideoxy-3-C-methyl-alpha-L-lyxo-hexopyranosyl)-beta-D-glucopyranosyloxy]-3-(carbamoylmethyl)-10,19-dichloro-2,3,4,5,6,7,23,25,26,36,37,38,38a-tetradecahydro-7,22,28,30,32-pentahydroxy-6-(N-methyl-D-leucyl)-2,5,24,38,39-pentaoxo-1H,22H-23,36-(epiminomethano)-8,11:18,21-dietheno-13,16:31,35-di(metheno)[1,6,9]oxadiazacyclohexadecino[4,5-m][10,2,16]benzoxadiazacyclotetracosine-26-carboxylic acid, a complex glycopeptide from Streptomyces orientalis that inhibits a specific step in the synthesis of the peptidoglycan layer in Gram-positive bacteria.
33073	pinene metabolic process	P	The chemical reactions and pathways involving the monoterpenoid pinene; alpha-pinene is (1S,5S)-2,6,6-trimethylbicyclo[3.1.1]hept-2-ene, and beta-pinene is (1S,5S)-6,6-dimethyl-2-methylenebicyclo[3.1.1]heptane.
33074	pinene catabolic process	P	The chemical reactions and pathways leading to the breakdown of the monoterpenoid pinene; alpha-pinene is (1S,5S)-2,6,6-trimethylbicyclo[3.1.1]hept-2-ene, and beta-pinene is (1S,5S)-6,6-dimethyl-2-methylenebicyclo[3.1.1]heptane.
33075	isoquinoline alkaloid biosynthetic process	P	The chemical reactions and pathways resulting in the formation of isoquinoline alkaloids, alkaloid compounds that contain bicyclic N-containing aromatic rings and are derived from a 3,4-dihydroxytyramine (dopamine) precursor that undergoes a Schiff base addition with aldehydes of different origin.
33076	isoquinoline alkaloid metabolic process	P	The chemical reactions and pathways involving isoquinoline alkaloids, alkaloid compounds that contain bicyclic N-containing aromatic rings and are derived from a 3,4-dihydroxytyramine (dopamine) precursor that undergoes a Schiff base addition with aldehydes of different origin.
33077	T cell differentiation in thymus	P	The process in which a precursor cell type acquires the specialized features of a T cell via a differentiation pathway dependent upon transit through the thymus.
33078	extrathymic T cell differentiation	P	The process in which a precursor cell type acquires the specialized features of a T cell via a differentiation pathway independent of the thymus.
33079	immature T cell proliferation	P	The expansion of an immature T cell population by cell division.
33080	immature T cell proliferation in thymus	P	The expansion of an immature T cell population by cell division in the thymus.
33081	regulation of T cell differentiation in thymus	P	Any process that modulates the frequency, rate or extent of T cell differentiation in the thymus.
33082	regulation of extrathymic T cell differentiation	P	Any process that modulates the frequency, rate or extent of extrathymic T cell differentiation.
33083	regulation of immature T cell proliferation	P	Any process that modulates the frequency, rate or extent of immature T cell proliferation.
33084	regulation of immature T cell proliferation in thymus	P	Any process that modulates the frequency, rate or extent of immature T cell proliferation in the thymus.
33085	negative regulation of T cell differentiation in thymus	P	Any process that stops, prevents, or reduces the frequency, rate or extent of T cell differentiation in the thymus.
33086	negative regulation of extrathymic T cell differentiation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of extrathymic T cell differentiation.
33087	negative regulation of immature T cell proliferation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of immature T cell proliferation.
33088	negative regulation of immature T cell proliferation in thymus	P	Any process that stops, prevents, or reduces the frequency, rate or extent of immature T cell proliferation in the thymus.
33089	positive regulation of T cell differentiation in thymus	P	Any process that activates or increases the frequency, rate or extent of T cell differentiation in the thymus.
33090	positive regulation of extrathymic T cell differentiation	P	Any process that activates or increases the frequency, rate or extent of extrathymic T cell differentiation.
33091	positive regulation of immature T cell proliferation	P	Any process that activates or increases the frequency, rate or extent of immature T cell proliferation.
33092	positive regulation of immature T cell proliferation in thymus	P	Any process that activates or increases the frequency, rate or extent of immature T cell proliferation in the thymus.
33093	Weibel-Palade body	C	A large, elongated, rod-shaped secretory granule characteristic of vascular endothelial cells that contain a number of structurally and functionally distinct proteins, of which the best characterized are von Willebrand factor (VWF) and P-selectin. Weibel-Palade bodies are formed from the trans-Golgi network in a process that depends on VWF, which is densely packed in a highly organized manner, and on coat proteins that remain associated with the granules. Upon cell stimulation, regulated exocytosis releases the contained proteins to the cell surface, where they act in the recruitment of platelets and leukocytes and in inflammatory and vasoactive responses.
33094	butane-1,4-diamine:2-oxoglutarate aminotransferase activity	F	Catalysis of the reaction: putrescine + 2-oxoglutarate = L-glutamate + 1-pyrroline + H2O.
33095	aleurone grain	C	A membrane-bounded storage granule found in cells of the aleurone layer in plants; contains either a protein matrix, protein-carbohydrate bodies and/or globoids. Aleurone grains are formed by the vacuole, rough endoplasmic reticulum and dictyosomes.
33096	amyloplast envelope	C	The double lipid bilayer enclosing the amyloplast and separating its contents from the rest of the cytoplasm; includes the intermembrane space.
33097	amyloplast membrane	C	Either of the lipid bilayers that surround an amyloplast and form the amyloplast envelope.
33098	amyloplast inner membrane	C	The inner, i.e. lumen-facing, lipid bilayer of the amyloplast envelope; also faces the amyloplast stroma.
33099	attachment organelle	C	A membrane-bounded extension of the cell, originally characterized in Mycoplasma species, that contains an electron-dense core that is part of the cytoskeleton and is oriented lengthwise and ends distally in a bulbous knob (terminal button). Required for adherence to host cells and involved in gliding motility and cell division.
33100	NuA3 histone acetyltransferase complex	C	A Gcn5-independent multisubunit complex that catalyzes the acetylation of histone H3. The budding yeast complex includes Sas3p, Taf30p, and Yng1p.
33101	cellular bud membrane	C	The portion of the plasma membrane surrounding a cellular bud.
33102	acidocalcisome membrane	C	The lipid bilayer surrounding an acidocalcisome.
33103	protein secretion by the type VI secretion system	P	The process in which proteins are transferred into the extracellular milieu or directly into host cells by the type VI secretion system. Proteins secreted by this system do not require an N-terminal signal sequence.
33104	type VI protein secretion system complex	C	A complex of proteins that permits the transfer of proteins into the extracellular milieu or directly into host cells via the type VI secretion system. Proteins secreted by this complex do not require an N-terminal signal sequence.
33105	chlorosome envelope	C	The structure, composed of a monolayer of glycolipids with embedded proteins, that encloses the pigments and other contents of the chlorosome.
33106	cis-Golgi network membrane	C	The lipid bilayer surrounding any of the compartments that make up the cis-Golgi network.
33107	CVT vesicle	C	A cytosolic vesicle that is enclosed by a double membrane and is implicated in the cytoplasm to vacuole targeting pathway. These vesicles are found in the yeast S. cerevisiae, and contain vacuolar hydrolases, aminopeptidase I (Ape1p) and alpha-mannosidase (Ams1p).
33108	mitochondrial respiratory chain complex assembly	P	The aggregation, arrangement and bonding together of a set of components to form a mitochondrial respiratory chain complex.
33110	Cvt vesicle membrane	C	Either of the two lipid bilayers surrounding a Cvt vesicle, a vesicle that functions in the cytoplasm-to-vacuole targeting (Cvt) pathway.
33111	attachment organelle membrane	C	The lipid bilayer surrounding an attachment organelle. This is a region of the cell membrane facing the environment - in mycoplasma, part of the mycolate outer membrane.
33112	cyanelle envelope	C	The double lipid bilayer enclosing the cyanelle and separating its contents from the rest of the cytoplasm; includes the intermembrane space.
33113	cyanelle membrane	C	Either of the lipid bilayers that surround a cyanelle and form the cyanelle envelope.
33114	cyanelle thylakoid lumen	C	The volume enclosed by a cyanelle thylakoid membrane.
33115	cyanelle thylakoid membrane	C	The lipid bilayer membrane of any thylakoid within a cyanelle.
33116	endoplasmic reticulum-Golgi intermediate compartment membrane	C	The lipid bilayer surrounding any of the compartments of the endoplasmic reticulum (ER)-Golgi intermediate compartment system.
33117	esterosome	C	A vesicle filled with crystalline protein that shows sequence similarities with various esterases.
33118	esterosome membrane	C	The lipid bilayer surrounding an esterosome. This membrane has characteristics of rough endoplasmic reticulum (RER) membranes.
33119	negative regulation of RNA splicing	P	Any process that stops, prevents, or reduces the frequency, rate or extent of RNA splicing.
33120	positive regulation of RNA splicing	P	Any process that activates or increases the frequency, rate or extent of RNA splicing.
33121	regulation of purine nucleotide catabolic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of purine nucleotides.
33122	negative regulation of purine nucleotide catabolic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of purine nucleotides.
33123	positive regulation of purine nucleotide catabolic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of purine nucleotides.
33127	regulation of histone phosphorylation	P	Any process that modulates the frequency, rate or extent of the addition of one or more phosphate groups to a histone protein.
33128	negative regulation of histone phosphorylation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the addition of one or more phosphate groups to a histone protein.
33129	positive regulation of histone phosphorylation	P	Any process that activates or increases the frequency, rate or extent of the addition of one or more phosphate groups to a histone protein.
33130	acetylcholine receptor binding	F	Interacting selectively and non-covalently with an acetylcholine receptor.
33131	regulation of glucokinase activity	P	Any process that modulates the frequency, rate or extent of glucokinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a glucose molecule.
33132	negative regulation of glucokinase activity	P	Any process that stops, prevents, or reduces the frequency, rate or extent of glucokinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a glucose molecule.
33133	positive regulation of glucokinase activity	P	Any process that activates or increases the frequency, rate or extent of glucokinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a glucose molecule.
33134	ubiquitin activating enzyme binding	F	Interacting selectively and non-covalently with a ubiquitin activating enzyme, any of the E1 proteins.
33135	regulation of peptidyl-serine phosphorylation	P	Any process that modulates the frequency, rate or extent of the phosphorylation of peptidyl-serine.
33136	serine phosphorylation of STAT3 protein	P	The process of introducing a phosphate group to a serine residue of the STAT3 protein.
33137	negative regulation of peptidyl-serine phosphorylation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the phosphorylation of peptidyl-serine.
33138	positive regulation of peptidyl-serine phosphorylation	P	Any process that activates or increases the frequency, rate or extent of the phosphorylation of peptidyl-serine.
33139	regulation of peptidyl-serine phosphorylation of STAT protein	P	Any process that modulates the frequency, rate or extent of the phosphorylation of a serine residue of a STAT (Signal Transducer and Activator of Transcription) protein.
33140	negative regulation of peptidyl-serine phosphorylation of STAT protein	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the phosphorylation of a serine residue of a STAT (Signal Transducer and Activator of Transcription) protein.
33141	positive regulation of peptidyl-serine phosphorylation of STAT protein	P	Any process that activates or increases the frequency, rate or extent of the phosphorylation of a serine residue of a STAT (Signal Transducer and Activator of Transcription) protein.
33142	progesterone receptor binding	F	Interacting selectively and non-covalently with a progesterone receptor.
33143	regulation of intracellular steroid hormone receptor signaling pathway	P	Any process that modulates the frequency, rate or extent of the activity of any intracellular steroid hormone receptor signaling pathway.
33144	negative regulation of intracellular steroid hormone receptor signaling pathway	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of any intracellular steroid hormone receptor signaling pathway.
33145	positive regulation of intracellular steroid hormone receptor signaling pathway	P	Any process that activates or increases the frequency, rate or extent of the activity of any intracellular steroid hormone receptor signaling pathway.
33146	regulation of intracellular estrogen receptor signaling pathway	P	Any process that modulates the frequency, rate or extent of the activity of an intracellular estrogen receptor signaling pathway.
33147	negative regulation of intracellular estrogen receptor signaling pathway	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of an intracellular estrogen receptor signaling pathway.
33148	positive regulation of intracellular estrogen receptor signaling pathway	P	Any process that activates or increases the frequency, rate or extent of the activity of an intracellular estrogen receptor signaling pathway.
33149	FFAT motif binding	F	Interacting selectively and non-covalently with the FFAT motif, a short motif containing diphenylalanine in an acidic tract that targets proteins to the cytosolic surface of the ER and to the nuclear membrane by binding directly to members of the VAP (VAMP-associated protein) protein family.
33150	cytoskeletal calyx	C	A large cytoskeletal structure located at the posterior end of the perinuclear theca of a mammalian sperm head. The nucleus is tightly associated with the calyx, which contains calicin and basic cylicin proteins.
33151	V(D)J recombination	P	The process in which immune receptor V, D, and J, or V and J gene segments, depending on the specific receptor, are recombined within a single locus utilizing the conserved heptamer and nonomer recombination signal sequences (RSS).
33152	immunoglobulin V(D)J recombination	P	The process in which immunoglobulin gene segments are recombined within a single locus utilizing the conserved heptamer and nonomer recombination signal sequences (RSS). For immunoglobulin heavy chains V, D, and J gene segments are joined, and for immunoglobulin light chains V and J gene segments are joined.
33153	T cell receptor V(D)J recombination	P	The process in which T cell receptor V, D, and J, or V and J gene segments, depending on the specific locus, are recombined within a single locus utilizing the conserved heptamer and nonomer recombination signal sequences (RSS).
33154	oligogalacturonide-transporting ATPase activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + oligogalacturonide(out) = ADP + phosphate + oligogalacturonide(in).
33155	oligogalacturonide transmembrane transporter activity	F	Enables the transfer of oligogalacturonide from one side of the membrane to the other.
33156	oligogalacturonide transport	P	The directed movement of oligogalacturonides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
33157	regulation of intracellular protein transport	P	Any process that modulates the frequency, rate or extent of the directed movement of proteins within cells.
33158	regulation of protein import into nucleus, translocation	P	Any process that modulates the vectorial transfer of a protein from the cytoplasm into the nucleus, across the nuclear membrane.
33159	negative regulation of protein import into nucleus, translocation	P	Any process that stops, prevents or reduces the vectorial transfer of a protein from the cytoplasm into the nucleus, across the nuclear membrane.
33160	positive regulation of protein import into nucleus, translocation	P	Any process that activates or increases the vectorial transfer of a protein from the cytoplasm into the nucleus, across the nuclear membrane.
33161	mitogen-activated protein kinase kinase kinase kinase binding	F	Interacting selectively and non-covalently with a mitogen-activated protein kinase kinase kinase kinase, any protein that can phosphorylate a MAP kinase kinase kinase.
33162	melanosome membrane	C	The lipid bilayer surrounding a melanosome.
33163	microneme membrane	C	The lipid bilayer surrounding a microneme.
33164	glycolipid 6-alpha-mannosyltransferase activity	F	Catalysis of the transfer of an alpha-D-mannosyl residue from GDP-mannose into lipid-linked oligosaccharide, forming an alpha-(1->6)-D-mannosyl-D-mannose linkage.
33165	interphotoreceptor matrix	C	A specialized extracellularc matrix that surrounds the photoreceptors of the retina and lies between them and the apical surface of the retinal pigment epithelium. The IPM has been implicated in several important activities required for photoreceptor function and maintenance.
33166	hyaline layer	C	A multilayered extraembryonic matrix that functions as a substrate for cell adhesion through early development. It is thought to protect and lubricate the embryo, stabilize the blastomeres during morphogenesis, and regulate nutrient intake. The major constituent of the hyaline layer is the protein hyalin. This matrix has been found in echinoderms.
33167	ARC complex	C	A ribonucleoprotein complex that contains members of the Argonaute family of proteins, additional protein subunits, and duplex siRNA; required for heterochromatin assembly and siRNA generation. Possibly involved in the conversion of ds siRNA to ss siRNA.
33168	conversion of ds siRNA to ss siRNA involved in RNA interference	P	The process in which double-stranded siRNA molecules are converted to single-stranded siRNAs; required for the formation of a mature RITS complex during RNA interference.
33169	histone H3-K9 demethylation	P	The modification of histone H3 by the removal of a methyl group from lysine at position 9 of the histone.
33170	protein-DNA loading ATPase activity	F	Catalysis of the reaction: ATP + H2O = ADP + phosphate, to drive the assembly of a protein or protein complex onto a DNA molecule.
33172	gas vesicle shell	C	The proteinaceous structure surrounding a gas vesicle.
33173	calcineurin-NFAT signaling cascade	P	Any intracellular signal transduction in which the signal is passed on within the cell by activation of a member of the NFAT protein family as a consequence of NFAT dephosphorylation by Ca(2+)-activated calcineurin. The cascade begins with calcium-dependent activation of the phosphatase calcineurin. Calcineurin dephosphorylates multiple phosphoserine residues on NFAT, resulting in the translocation of NFAT to the nucleus. The cascade ends with regulation of transcription by NFAT. The calcineurin-NFAT cascade lies downstream of many cell surface receptors, including G-protein coupled receptors (GPCRs) and receptor tyrosine kinases (RTKs) that signal to mobilize calcium ions (Ca2+).
33174	chloroplast proton-transporting ATP synthase complex, catalytic core CF(1)	C	The catalytic sector of the mitochondrial hydrogen-transporting ATP synthase; it comprises the catalytic core and central stalk, and is peripherally associated with the chloroplast thylakoid membrane when the entire ATP synthase is assembled. The chloroplast F0 domain contains three alpha, three beta, one gamma, one delta, and one epsilon subunits.
33175	chloroplast proton-transporting ATP synthase complex, coupling factor CF(o)	C	All non-F1 subunits of the chloroplast hydrogen-transporting ATP synthase, including integral and peripheral chloroplast thylakoid membrane proteins.
33176	proton-transporting V-type ATPase complex	C	A proton-transporting two-sector ATPase complex that couples ATP hydrolysis to the transport of protons across a concentration gradient. The resulting transmembrane electrochemical potential of H+ is used to drive a variety of (i) secondary active transport systems via H+-dependent symporters and antiporters and (ii) channel-mediated transport systems. The complex comprises a membrane sector (V0) that carries out proton transport and a cytoplasmic compartment sector (V1) that catalyzes ATP hydrolysis. V-type ATPases are found in the membranes of organelles such as vacuoles, endosomes, and lysosomes, and in the plasma membrane.
33177	proton-transporting two-sector ATPase complex, proton-transporting domain	C	A protein complex that forms part of a proton-transporting two-sector ATPase complex and carries out proton transport across a membrane. The proton-transporting domain (F0, V0, or A0) includes integral and peripheral membrane proteins.
33178	proton-transporting two-sector ATPase complex, catalytic domain	C	A protein complex that forms part of a proton-transporting two-sector ATPase complex and catalyzes ATP hydrolysis or synthesis. The catalytic domain (F1, V1, or A1) comprises a hexameric catalytic core and a central stalk, and is peripherally associated with the membrane when the two-sector ATPase is assembled.
33179	proton-transporting V-type ATPase, V0 domain	C	A protein complex that forms part of a proton-transporting V-type ATPase and mediates proton transport across a membrane. The V0 complex consists of at least four different subunits (a,c,d and e); six or more c subunits form a proton-binding rotor ring.
33180	proton-transporting V-type ATPase, V1 domain	C	A protein complex that forms part of a proton-transporting V-type ATPase and catalyzes ATP hydrolysis. The V1 complex consists of: (1) a globular headpiece with three alternating copies of subunits A and B that form a ring, (2) a central rotational stalk composed of single copies of subunits D and F, and (3) a peripheral stalk made of subunits C, E, G and H. Subunits A and B mediate the hydrolysis of ATP at three reaction sites associated with subunit A.
33181	plasma membrane proton-transporting V-type ATPase complex	C	A proton-transporting two-sector ATPase complex found in the plasma membrane.
33182	regulation of histone ubiquitination	P	Any process that modulates the frequency, rate or extent of the addition of a ubiquitin group to a histone protein.
33183	negative regulation of histone ubiquitination	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the addition of a ubiquitin group to a histone protein.
33184	positive regulation of histone ubiquitination	P	Any process that activates or increases the frequency, rate or extent of the addition of a ubiquitin group to a histone protein.
33185	dolichol-phosphate-mannose synthase complex	C	A protein complex that possesses dolichyl-phosphate beta-D-mannosyltransferase activity; contains a catalytic subunit, a regulatory subunit, and a third subunit that stabilizes the complex. In human and several other metazoa, the subunits are named DPM1, DPM2 and DPM3, respectively.
33186	CAF-1 complex	C	A conserved heterotrimeric protein complex that promotes histone H3 and H4 deposition onto newly synthesized DNA during replication or DNA repair; specifically facilitates replication-dependent nucleosome assembly with the major histone H3 (H3.1). In many species the CAF-1 subunits are designated p150, p60, and p48.
33188	sphingomyelin synthase activity	F	Catalysis of the reaction: 1,2-diacyl-sn-glycero-3-phosphocholine + ceramide = 1,2-diacyl-sn-glycerol + sphingomyelin.
33189	response to vitamin A	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin A stimulus.
33190	solanapyrone synthase activity	F	Catalysis of the cyclization of double bonds in prosolanapyrone II to form (-)-solanapyrone A.
33191	macrophomate synthase activity	F	Catalysis of the reaction: a 2-pyrone + oxalacetate = macrophomate.
33192	calmodulin-dependent protein phosphatase activity	F	Catalysis of the reaction: protein serine/threonine phosphate + H2O = protein serine/threonine + phosphate, dependent on the presence of calcium-bound calmodulin.
33193	Lsd1/2 complex	C	A nucleosome-binding protein complex that comprises two SWIRM domain histone demethylases and two PHD finger proteins. The complex is involved in transcriptional regulation via heterochromatic silencing and the regulation of chromatin boundary formation, and was first identified in fission yeast.
33194	response to hydroperoxide	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydroperoxide stimulus. Hydroperoxides are monosubstitution products of hydrogen peroxide, HOOH.
33195	response to alkyl hydroperoxide	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alkyl hydroperoxide stimulus. Alkyl hydroperoxides are monosubstitution products of hydrogen peroxide, HOOH, where the substituent is an alkyl group.
33196	tryparedoxin peroxidase activity	F	Catalysis of the reaction: tryparedoxin + hydrogen peroxide = tryparedoxin disulfide + H2O.
33197	response to vitamin E	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin E stimulus.
33198	response to ATP	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ATP (adenosine 5'-triphosphate) stimulus.
33200	inositol heptakisphosphate 5-kinase activity	F	Catalysis of the reaction: ATP + 4-diphospho-1D-myo-inositol (1,2,3,5,6)pentakisphosphate = 4,5-bisdiphosphoinositol-1D-myoinositol (1,2,3,6)tetrakisphosphate, and ATP + 6-diphospho-1D-myo-inositol (1,2,3,4,5)pentakisphosphate = 5,6-bisdiphosphoinositol-1D-myoinositol (1,2,3,4)tetrakisphosphate.
33201	alpha-1,4-glucan synthase activity	F	Catalysis of the reaction: RDP-glucose + [alpha-D-glucosyl-(1,4)]n = RDP + [alpha-D-glucosyl-(1,4)]n+1, where RDP is ADP or UDP.
33202	DNA helicase complex	C	A protein complex that possesses DNA helicase activity.
33203	DNA helicase A complex	C	A homohexameric protein complex that possesses DNA helicase activity; associates with DNA polymerase alpha-primase and translocates in the 5' to 3' direction.
33204	ribonuclease P RNA binding	F	Interacting selectively and non-covalently with the RNA subunit of ribonuclease P.
33206	meiotic cytokinesis	P	A cell cycle process that results in the division of the cytoplasm of a cell after meiosis, resulting in the separation of the original cell into two daughter cells.
33207	beta-1,4-N-acetylgalactosaminyltransferase activity	F	Catalysis of the transfer of an N-acetylgalactosaminyl residue from UDP-N-acetyl-galactosamine to an acceptor molecule, forming a beta-1,4 linkage.
33208	UDP-N-acetylgalactosamine:N-acetylneuraminyl-alpha-2,3-galactosyl-beta-R 1,4-N-acetylgalactosaminyltransferase activity	F	Catalysis of the reaction: UDP-N-acetylgalactosamine + N-acetylneuraminyl-alpha-2,3-galactosyl-beta-oligosaccharide = UDP + N-acetylgalactosaminyl-N-acetylneuraminyl-alpha-2,3-galactosyl-beta-oligosaccharide.
33209	tumor necrosis factor-mediated signaling pathway	P	A series of molecular signals initiated by the binding of a tumor necrosis factor to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.
33210	leptin-mediated signaling pathway	P	A series of molecular signals initiated by the binding of leptin to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. Leptin is a hormone manufactured primarily in the adipocytes of white adipose tissue, and the level of circulating leptin is directly proportional to the total amount of fat in the body.
33211	adiponectin-activated signaling pathway	P	A series of molecular signals initiated by the binding of adiponectin to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.
33212	iron assimilation	P	A process in which iron is solubilized and transported into a cell.
33213	iron assimilation by capture and transport	P	A process in which iron (Fe3+) is solubilized by binding to a receptor or transport protein and transported into a cell.
33214	iron assimilation by chelation and transport	P	A process in which iron (Fe3+) is solubilized by ferric iron-specific chelators, known as siderophores, excreted by a cell; the iron-siderophore complex is then transported into the cell by specific cell surface receptors.
33215	iron assimilation by reduction and transport	P	A process in which iron is solubilized by reduction from Fe3+ to Fe2+ via a cell surface reductase and subsequent transport of the iron across the membrane by iron uptake proteins.
33216	ferric iron import	P	The directed movement of ferric iron (Fe(III) or Fe3+) ions into a cell or organelle.
33217	regulation of transcription from RNA polymerase II promoter in response to iron ion starvation	P	Modulation of the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of deprivation of iron ions.
33218	amide binding	F	Interacting selectively and non-covalently with an amide, any derivative of an oxoacid in which an acidic hydroxy group has been replaced by an amino or substituted amino group.
33219	urea binding	F	Interacting selectively and non-covalently with urea, a water-soluble carboxamide with the structure H2N-CO-NH2.
33220	amide-transporting ATPase activity	F	Catalysis of the reaction: ATP + H2O + amide(out) = ADP + phosphate + amide(in).
33221	urea-transporting ATPase activity	F	Catalysis of the reaction: ATP + H2O + urea(out) = ADP + phosphate + urea(in).
33222	xylose binding	F	Interacting selectively and non-covalently with the D- or L-enantiomer of xylose.
33223	2-aminoethylphosphonate transport	P	The directed movement of 2-aminoethylphosphonate, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
33224	2-aminoethylphosphonate transmembrane transporter activity	F	Enables the directed movement of 2-aminoethylphosphonate into, out of or within a cell, or between cells.
33225	2-aminoethylphosphonate-transporting ATPase activity	F	Catalysis of the reaction: ATP + H2O + 2-aminoethylphosphonate(out) = ADP + phosphate + 2-aminoethylphosphonate(in).
33226	2-aminoethylphosphonate binding	F	Interacting selectively and non-covalently with 2-aminoethylphosphonate.
33227	dsRNA transport	P	The directed movement of dsRNA, double-stranded ribonucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
33228	cysteine export	P	The directed movement of cysteine out of a cell or organelle.
33229	cysteine transmembrane transporter activity	F	Enables the transfer of cysteine from one side of the membrane to the other.
33230	cysteine-transporting ATPase activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + cysteine(out/in) = ADP + phosphate + cysteine(in/out).
33231	carbohydrate export	P	The directed movement of carbohydrates out of a cell or organelle.
33232	D-methionine-transporting ATPase activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + D-methionine(out/in) = ADP + phosphate + D-methionine(in/out).
33233	regulation of protein sumoylation	P	Any process that modulates the frequency, rate or extent of the addition of SUMO groups to a protein.
33234	negative regulation of protein sumoylation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the addition of SUMO groups to a protein.
33235	positive regulation of protein sumoylation	P	Any process that activates or increases the frequency, rate or extent of the addition of SUMO groups to a protein.
33238	regulation of cellular amine metabolic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways by which individual cells transform amines.
33239	negative regulation of cellular amine metabolic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving amines.
33240	positive regulation of cellular amine metabolic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving amines.
33241	regulation of cellular amine catabolic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of amines.
33242	negative regulation of cellular amine catabolic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of amines.
33243	positive regulation of cellular amine catabolic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of amines.
33244	regulation of penicillin metabolic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving any antibiotic that contains the condensed beta-lactamthiazolidine ring system.
33245	negative regulation of penicillin metabolic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving any antibiotic that contains the condensed beta-lactamthiazolidine ring system.
33246	positive regulation of penicillin metabolic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving any antibiotic that contains the condensed beta-lactamthiazolidine ring system.
33247	regulation of penicillin catabolic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of any antibiotic that contains the condensed beta-lactamthiazolidine ring system.
33248	negative regulation of penicillin catabolic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of any antibiotic that contains the condensed beta-lactamthiazolidine ring system.
33249	positive regulation of penicillin catabolic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways leading to the breakdown of any antibiotic that contains the condensed beta-lactamthiazolidine ring system.
33250	penicillinase activity	F	Catalysis of the reaction: a penicillin + H2O = a substituted beta-amino acid derivative of the penicillin.
33251	cephalosporinase activity	F	Catalysis of the reaction: a cephalosporin + H2O = a substituted beta-amino acid derivative of the cephalosporin.
33252	regulation of beta-lactamase activity	P	Any process that modulates the frequency, rate or extent of beta-lactamase activity, the hydrolysis of a beta-lactam to yield a substituted beta-amino acid.
33253	regulation of penicillinase activity	P	Any process that modulates the frequency, rate or extent of nuclease activity, the hydrolysis of a penicillin to yield a substituted beta-amino acid derivative.
33254	vacuolar transporter chaperone complex	C	A protein complex that contains four related proteins that have been implicated in several membrane-related processes, such as sorting of H+-translocating ATPases, endocytosis, ER-Golgi trafficking, vacuole fusion, vacuolar polyphosphate homeostasis and the microautophagic scission of vesicles into the vacuolar lumen. The complex is enriched at the vacuolar membrane, but also found in other cellular compartments, including the ER and the cell periphery. In Saccharomyces, the subunits are Vtc1p, Vtc2p, Vtc3p and Vtc4p.
33255	SAS acetyltransferase complex	C	A protein complex that possesses histone acetyltransferase activity and links histone acetylation to the assembly of transcriptionally silent chromatin. In vitro, the complex acetylates lysine 16 of histone H4 and lysine 14 of histone H3, although the latter may not be relevant in vivo. The complex contains a catalytic subunit and at least two other subunits; in Saccharomyces, the catalytic subunit is Sas2p and additional subunits are Sas4p and Sas5p.
33256	I-kappaB/NF-kappaB complex	C	A protein complex containing an inhibitory-kappaB (I-kappaB/IKB) protein and one or more copies of an NF-kappaB protein. In the resting state, NF-kappaB dimers are bound to I-kappaB proteins, sequestering NF-kappaB in the cytoplasm.
33257	Bcl3/NF-kappaB2 complex	C	A protein complex containing one Bcl protein and one or more copies of NF-kappaB2; formation of complexes of different stoichiometry depends on the Bcl3:NF-kappaB2 ratio, and allow Bcl3 to exert different regulatory effects on NF-kappaB2-dependent transcription.
33258	plastid DNA metabolic process	P	The chemical reactions and pathways involving plastid DNA.
33259	plastid DNA replication	P	The process in which new strands of DNA are synthesized in a plastid.
33260	nuclear DNA replication	P	The DNA-dependent DNA replication that occurs in the nucleus of eukaryotic organisms as part of the cell cycle.
33262	regulation of nuclear cell cycle DNA replication	P	Any process that modulates the frequency, rate or extent of The DNA-dependent DNA replication that occurs in the nucleus of eukaryotic organisms as part of the cell cycle.
33263	CORVET complex	C	A multimeric protein complex that acts as an endosomal tethering complex (CORVET = class C core vacuole/endosome tethering) by cooperating with Rab GTPases to capture endosomal vesicles and trap them prior to the action of SNAREs; the complex is involved in endo-lysosomal biogenesis and required for transport between endosome and vacuole. The Saccharomyces cerevisiae complex contains Vps8p, Vps3p, Pep5p, Vps16p, Pep3p, and Vps33p.
33265	choline binding	F	Interacting selectively and non-covalently with choline, the amine 2-hydroxy-N,N,N-trimethylethanaminium.
33266	choline-transporting ATPase activity	F	Catalysis of the reaction: ATP + H2O = ADP + phosphate, to directly drive the transport of choline across a membrane.
33267	axon part	C	A part of an axon, a cell projection of a neuron.
33268	node of Ranvier	C	An axon part that is a gap in the myelin where voltage-gated sodium channels cluster and saltatory conduction is executed.
33269	internode region of axon	C	An axon part that is located between the nodes of Ranvier and surrounded by compact myelin sheath.
33270	paranode region of axon	C	An axon part that is located adjacent to the nodes of Ranvier and surrounded by lateral loop portions of myelin sheath.
33271	myo-inositol phosphate transport	P	The directed movement of any phosphorylated myo-inositol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
33272	myo-inositol hexakisphosphate transport	P	The directed movement of myo-inositol hexakisphosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
33273	response to vitamin	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin stimulus.
33274	response to vitamin B2	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin B2 stimulus.
33275	actin-myosin filament sliding	P	The sliding movement of actin thin filaments and myosin thick filaments past each other.
33276	transcription factor TFTC complex	C	A protein complex that does not contain either a TATA-binding protein (TBP) or a TBP-like factor, but is composed of several TAFIIs and other proteins, including a histone acetyltransferase. This complex is able to nucleate transcription initiation by RNA polymerase II, can mediate transcriptional activation, and has histone acetyltransferase activity.
33277	abortive mitotic cell cycle	P	A cell cycle in which mitosis is begun and progresses normally through the end of anaphase, but not completed, resulting in a cell with increased ploidy.
33278	cell proliferation in midbrain	P	The multiplication or reproduction of cells, resulting in the expansion of a cell population in the midbrain.
33280	response to vitamin D	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin D stimulus.
33281	TAT protein transport complex	C	A complex of three proteins integral to the cytoplasmic membrane of bacteria and membranes of organelles derived from bacteria (chloroplasts and mitochondria) involved in membrane transport of folded proteins.
33282	protein C inhibitor-acrosin complex	C	A heterodimeric protein complex of protein C inhibitor (SERPINA5) and acrosin; formation of the complex inhibits the protease activity of acrosin.
33283	organic acid-transporting ATPase activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + organic acid(out/in) = ADP + phosphate + organic acid(in/out).
33284	carboxylic acid-transporting ATPase activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + carboxylic acid(out/in) = ADP + phosphate + carboxylic acid(in/out).
33285	monocarboxylic acid-transporting ATPase activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + monocarboxylic acid(out/in) = ADP + phosphate + monocarboxylic acid(in/out).
33286	ectoine-transporting ATPase activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + ectoine(out/in) = ADP + phosphate + ectoine(in/out).
33287	hydroxyectoine transmembrane transporter activity	F	Enables the transfer of hydroxyectoine from one side of the membrane to the other.
33288	hydroxyectoine-transporting ATPase activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + hydroxyectoine(out/in) = ADP + phosphate + hydroxyectoine(in/out).
33289	intraconoid microtubule	C	A microtubule located such that it threads through the conoid and projects through the polar ring.
33290	eukaryotic 48S preinitiation complex	C	A protein complex composed of the small ribosomal subunit, eIF3, eIF1A, methionyl-initiatior methionine and a capped mRNA. The complex is initially positioned at the 5'-end of the capped mRNA.
33291	eukaryotic 80S initiation complex	C	A protein complex composed of the large and small ribosomal subunits, methionyl-initiatior tRNA, and the capped mRNA. The initiator tRNA is positioned at the ribosomal P site at the AUG codon corresponding to the beginning of the coding region.
33292	T-tubule organization	P	A process that is carried out at the cellular level that results in the assembly, arrangement of constituent parts, or disassembly of the T-tubule. A T-tubule is an invagination of the plasma membrane of a muscle cell that extends inward from the cell surface around each myofibril.
33293	monocarboxylic acid binding	F	Interacting selectively and non-covalently with a monocarboxylic acid, any organic acid containing one carboxyl (COOH) group or anion (COO-).
33294	ectoine binding	F	Interacting selectively and non-covalently with ectoine, 1,4,5,6-tetrahydro-2-methyl-4-pyrimidinecarboxylic acid.
33295	hydroxyectoine binding	F	Interacting selectively and non-covalently with hydroxyectoine.
33296	rhamnose binding	F	Interacting selectively and non-covalently with the D- or L-enantiomer of rhamnose.
33297	rhamnose-transporting ATPase activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + rhamnose(out/in) = ADP + phosphate + rhamnose(in/out).
33298	contractile vacuole organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a contractile vacuole. A specialized vacuole that fills with water from the cytoplasm and then discharges this externally by the opening of contractile vacuole pores.
33299	secretion of lysosomal enzymes	P	The controlled release of lysosomal enzymes by a cell.
33300	dehydroascorbic acid transporter activity	F	Enables the directed movement of dehydroascorbate, 5-(1,2-dihydroxyethyl)furan-2,3,4(5H)-trione, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
33301	cell cycle comprising mitosis without cytokinesis	P	A mitotic cell cycle in which mitosis is completed but cytokinesis does not occur, resulting in a cell containing multiple nuclei each with a chromosomal complement of the original ploidy (usually 2N).
33302	quercetin O-glucoside metabolic process	P	The chemical reactions and pathways involving O-glucosylated derivatives of quercetin.
33303	quercetin O-glucoside biosynthetic process	P	The chemical reactions and pathways leading to the formation of O-glucosylated derivatives of quercetin.
33304	chlorophyll a metabolic process	P	The chemical reactions and pathways involving chlorophyll a.
33305	chlorophyll a biosynthetic process	P	The chemical reactions and pathways leading to the formation of chlorophyll a.
33306	phytol metabolic process	P	The chemical reactions and pathways involving phytol, (2E,7R,11R)-3,7,11,15-tetramethylhexadec-2-en-1-ol.
33307	phytol salvage	P	A process that generates phytol, (2E,7R,11R)-3,7,11,15-tetramethylhexadec-2-en-1-ol, from derivatives of it without de novo synthesis.
33308	hydroxyectoine transport	P	The directed movement of hydroxyectoine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
33309	SBF transcription complex	C	A protein complex that binds to the Swi4/6 cell cycle box (SCB) promoter element, consensus sequence CRCGAAA, and activates transcription during the G1/S transition of the cell cycle. In Saccharomyces, the complex contains a heterodimer of the DNA binding protein Swi6p and the activator Swi4p, and is associated with additional proteins known as Whi5p and Msa1p.
33310	chlorophyll a catabolic process	P	The chemical reactions and pathways leading to the breakdown of chlorophyll a.
33311	chlorophyll a biosynthetic process via phytyl diphosphate	P	The chemical reactions and pathways leading to the formation of chlorophyll a, via the intermediate phytyl diphosphate.
33312	chlorophyll a biosynthetic process via geranylgeranyl-chlorophyll a	P	The chemical reactions and pathways leading to the formation of chlorophyll a, via the intermediate geranylgeranyl-chlorophyll a.
33313	meiotic cell cycle checkpoint	P	A cell cycle checkpoint that ensures accurate chromosome replication and segregation by preventing progression through a meiotic cell cycle until conditions are suitable for the cell to proceed to the next stage.
33314	mitotic DNA replication checkpoint	P	A cell cycle checkpoint that acts during a mitotic cell cycle and prevents the initiation of mitosis until DNA replication is complete, thereby ensuring that progeny inherit a full complement of the genome.
33315	meiotic DNA replication checkpoint	P	A cell cycle checkpoint that acts during a meiotic cell cycle and prevents the initiation of cell division until DNA replication is complete, thereby ensuring that progeny inherit a full complement of the haploid genome.
33316	meiotic spindle assembly checkpoint	P	A cell cycle checkpoint that delays the metaphase/anaphase transition of a meiotic cell cycle until the spindle is correctly assembled and chromosomes are attached to the spindle.
33317	pantothenate biosynthetic process from valine	P	The chemical reactions and pathways resulting in the formation of pantothenate, the anion of pantothenic acid, from other compounds, including valine.
33318	pantothenate biosynthetic process from 2-dehydropantolactone	P	The chemical reactions and pathways resulting in the formation of pantothenate, the anion of pantothenic acid, from other compounds, including 2-dehydropantolactone.
33319	UDP-D-xylose metabolic process	P	The chemical reactions and pathways involving UDP-D-xylose, uridinediphosphoxylose, a substance composed of xylose in glycosidic linkage with uridine diphosphate.
33320	UDP-D-xylose biosynthetic process	P	The chemical reactions and pathways resulting in the formation of UDP-D-xylose, uridinediphosphoxylose, a substance composed of xylose in glycosidic linkage with uridine diphosphate.
33321	homomethionine metabolic process	P	The chemical reactions and pathways involving homomethionine, a non-protein amino acid synthesized from methionine via chain elongation.
33322	homomethionine biosynthetic process	P	The chemical reactions and pathways resulting in the formation of homomethionine, a non-protein amino acid synthesized from methionine via chain elongation.
33323	choline biosynthetic process via CDP-choline	P	The chemical reactions and pathways resulting in the formation of choline (2-hydroxyethyltrimethylammonium), via the intermediate CDP-choline.
33324	choline biosynthetic process via N-monomethylethanolamine	P	The chemical reactions and pathways resulting in the formation of choline (2-hydroxyethyltrimethylammonium), via the intermediate N-monomethylethanolamine.
33325	choline biosynthetic process via phosphoryl-ethanolamine	P	The chemical reactions and pathways resulting in the formation of choline (2-hydroxyethyltrimethylammonium), via the intermediate phosphoryl-ethanolamine.
33326	cerebrospinal fluid secretion	P	The regulated release of cerebrospinal fluid (CSF) from the choroid plexus of the lateral, third and fourth ventricles. The cerebrospinal fluid is a clear liquid that located within the ventricles, spinal canal, and subarachnoid spaces.
33327	Leydig cell differentiation	P	The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a Leydig cell. A Leydig cell is a testosterone-secreting cell in the interstitial area, between the seminiferous tubules, in the testis.
33328	peroxisome membrane targeting sequence binding	F	Interacting selectively and non-covalently with a peroxisomal membrane targeting sequence, any of several sequences of amino acids within a protein that can act as a signal for the localization of the protein into the peroxisome membrane.
33329	kaempferol O-glucoside metabolic process	P	The chemical reactions and pathways involving O-glucosylated derivatives of kaempferol.
33330	kaempferol O-glucoside biosynthetic process	P	The chemical reactions and pathways leading to the formation of O-glucosylated derivatives of kaempferol.
33331	ent-kaurene metabolic process	P	The chemical reactions and pathways involving ent-kaur-16-ene. Ent-kaurene is a tetracyclic diterpenoid that is a precursor of several plant isoprenoids, including gibberellins.
33332	ent-kaurene biosynthetic process	P	The chemical reactions and pathways resulting in the formation of ent-kaurene. Ent-kaurene is a tetracyclic diterpenoid that is a precursor of several plant isoprenoids, including gibberellins.
33333	fin development	P	The process whose specific outcome is the progression of a fin over time, from its formation to the mature structure.
33334	fin morphogenesis	P	The process in which the anatomical structures of a fin are generated and organized.
33335	anal fin development	P	The process whose specific outcome is the progression of the anal fin over time, from its formation to the mature structure.
33336	caudal fin development	P	The process whose specific outcome is the progression of the caudal fin over time, from its formation to the mature structure.
33337	dorsal fin development	P	The process whose specific outcome is the progression of the dorsal fin over time, from its formation to the mature structure.
33338	medial fin development	P	The process whose specific outcome is the progression of a medial fin over time, from its formation to the mature structure.
33339	pectoral fin development	P	The process whose specific outcome is the progression of the pectoral fin over time, from its formation to the mature structure.
33340	pelvic fin development	P	The process whose specific outcome is the progression of the pelvic fin over time, from its formation to the mature structure.
33341	regulation of collagen binding	P	Any process that modulates the frequency, rate or extent of collagen binding.
33342	negative regulation of collagen binding	P	Any process that stops, prevents, or reduces the frequency, rate or extent of collagen binding.
33343	positive regulation of collagen binding	P	Any process that activates or increases the frequency, rate or extent of collagen binding.
33344	cholesterol efflux	P	The directed movement of cholesterol, cholest-5-en-3-beta-ol, out of a cell or organelle.
33345	asparagine catabolic process via L-aspartate	P	The chemical reactions and pathways resulting in the breakdown of glutamate, via the intermediate L-aspartate.
33346	asparagine catabolic process via 2-oxosuccinamate	P	The chemical reactions and pathways resulting in the breakdown of glutamate, via the intermediate 2-oxosuccinamate.
33347	tetrose metabolic process	P	The chemical reactions and pathways involving a tetrose, any monosaccharide with a chain of four carbon atoms in the molecule.
33348	tetrose biosynthetic process	P	The chemical reactions and pathways resulting in the formation of a tetrose, any monosaccharide with a chain of four carbon atoms in the molecule.
33349	apiose metabolic process	P	The chemical reactions and pathways involving apiose, the branched tetrose 3-C-(hydroxymethyl)-D-glycero-tetrose.
33350	apiose biosynthetic process	P	The chemical reactions and pathways resulting in the formation of apiose, the branched tetrose 3-C-(hydroxymethyl)-D-glycero-tetrose.
33351	UDP-D-apiose metabolic process	P	The chemical reactions and pathways involving UDP-D-apiose, uridinediphosphoapiose, a substance composed of apiose in glycosidic linkage with uridine diphosphate.
33352	UDP-D-apiose biosynthetic process	P	The chemical reactions and pathways resulting in the formation of UDP-D-apiose, uridinediphosphoapicose, a substance composed of apiose in glycosidic linkage with uridine diphosphate.
33353	S-adenosylmethionine cycle	P	A cyclic series of interconversions involving S-adenosylmethionine, S-adenosyl-L-homocysteine, L-cysteine, and L-methionine. Couples utilization of the methyl group of SAM with recycling of the homocysteinyl group and regeneration of methionine.
33354	chlorophyll cycle	P	A cyclic series of interconversions involving chlorophyll a, chlorophyll b and several chlorophyllide intermediates.
33355	ascorbate glutathione cycle	P	A cyclic series of interconversions involving L-ascorbate and glutathione that scavenges hydrogen peroxide and reduces it to water, with concomitant oxidation of NADPH.
33356	UDP-L-arabinose metabolic process	P	The chemical reactions and pathways involving UDP-L-arabinose, uridinediphosphoarabinose, a substance composed of arabinose in glycosidic linkage with uridine diphosphate.
33357	L-arabinose biosynthetic process	P	The chemical reactions and pathways resulting in the formation of L-arabinose, arabino-pentose.
33358	UDP-L-arabinose biosynthetic process	P	The chemical reactions and pathways resulting in the formation of UDP-L-arabinose, uridinediphosphoarabinose, a substance composed of arabinose in glycosidic linkage with uridine diphosphate.
33359	lysine biosynthetic process via diaminopimelate and N-succinyl-2-amino-6-ketopimelate	P	The chemical reactions and pathways resulting in the formation of lysine, via the intermediates diaminopimelate and N-succinyl-2-amino-6-ketopimelate; in this pathway tetrahydrodipicolinate is converted to meso-diaminopimelate in four enzymatic steps.
33360	lysine biosynthetic process via diaminopimelate and L-2-acetamido-6-oxoheptanedioate	P	The chemical reactions and pathways resulting in the formation of lysine, via the intermediates diaminopimelate and L-2-acetamido-6-oxoheptanedioate; in this pathway tetrahydrodipicolinate is converted to meso-diaminopimelate in four enzymatic steps.
33361	lysine biosynthetic process via diaminopimelate, dehydrogenase pathway	P	The chemical reactions and pathways resulting in the formation of lysine, via the intermediate diaminopimelate; in this pathway tetrahydrodipicolinate is converted to meso-diaminopimelate in a single enzymatic step.
33362	lysine biosynthetic process via diaminopimelate, diaminopimelate-aminotransferase pathway	P	The chemical reactions and pathways resulting in the formation of lysine, via the intermediate diaminopimelate; in this pathway tetrahydrodipicolinate is converted to meso-diaminopimelate in two enzymatic steps.
33363	secretory granule organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a secretory granule. A secretory granule is a small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion.
33364	mast cell secretory granule organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a secretory granule in a mast cell. A secretory granule is a small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion.
33365	protein localization to organelle	P	A process in which a protein is transported to, or maintained in, a location within an organelle.
33366	protein localization to secretory granule	P	A process in which a protein is transported to, or maintained in, a location within a secretory granule.
33367	protein localization to mast cell secretory granule	P	A process in which a protein is transported to, or maintained in, a location within a secretory granule in a mast cell.
33368	protease localization to mast cell secretory granule	P	Any process in which a protease is transported to, or maintained in, a location within a secretory granule in a mast cell.
33369	establishment of protein localization to mast cell secretory granule	P	The directed movement of a protein to a location within a secretory granule in a mast cell.
33370	maintenance of protein location in mast cell secretory granule	P	A process in which a protein is maintained in a secretory granule in a mast cell and prevented from moving elsewhere.
33371	T cell secretory granule organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a secretory granule in a T cell. A secretory granule is a small subcellular vesicle, surrounded by a membrane, that is formed from the Golgi apparatus and contains a highly concentrated protein destined for secretion.
33372	establishment of protease localization to mast cell secretory granule	P	The directed movement of a protease to a location within a secretory granule in a mast cell.
33373	maintenance of protease location in mast cell secretory granule	P	A process in which a protease is maintained in a secretory granule in a mast cell and prevented from moving elsewhere.
33374	protein localization to T cell secretory granule	P	A process in which a protein is transported to, or maintained in, a location within a secretory granule in a T cell.
33375	protease localization to T cell secretory granule	P	Any process in which a protease is transported to, or maintained in, a location within a secretory granule in a T cell.
33376	establishment of protein localization to T cell secretory granule	P	The directed movement of a protein to a location within a secretory granule in a T cell.
33377	maintenance of protein location in T cell secretory granule	P	A process in which a protein is maintained in a secretory granule in a T cell and prevented from moving elsewhere.
33378	establishment of protease localization to T cell secretory granule	P	The directed movement of a protease to a location within a secretory granule in a T cell.
33379	maintenance of protease location in T cell secretory granule	P	A process in which a protease is maintained in a secretory granule in a T cell and prevented from moving elsewhere.
33380	granzyme B localization to T cell secretory granule	P	Any process in which the protease granzyme B is transported to, or maintained in, a location within a secretory granule in a T cell.
33381	establishment of granzyme B localization to T cell secretory granule	P	The directed movement of the protease granzyme B to a location within a secretory granule in a T cell.
33382	maintenance of granzyme B location in T cell secretory granule	P	A process in which the protease granyme B is maintained in a secretory granule in a T cell and prevented from moving elsewhere.
33383	geranyl diphosphate metabolic process	P	The chemical reactions and pathways involving geranyl diphosphate, the universal precursor of the monoterpenes.
33384	geranyl diphosphate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of geranyl diphosphate.
33385	geranylgeranyl diphosphate metabolic process	P	The chemical reactions and pathways involving geranylgeranyl diphosphate, a polyprenol compound involved in the biosynthesis of a variety of terpenoids including chlorophylls, carotenoids, tocopherols, plastoquinones, and the plant hormones gibberellins.
33386	geranylgeranyl diphosphate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of geranylgeranyl diphosphate.
33387	putrescine biosynthetic process from ornithine	P	The chemical reactions and pathways resulting in the formation of putrescine, 1,4-diaminobutane by decarboxylation of ornithine.
33388	putrescine biosynthetic process from arginine	P	The chemical reactions and pathways resulting in the formation of putrescine, 1,4-diaminobutane, from other compounds, including arginine.
33389	putrescine biosynthetic process from arginine, using agmatinase	P	The chemical reactions and pathways resulting in the formation of putrescine, 1,4-diaminobutane, from other compounds, including arginine; in this pathway, arginine is converted to agmatine, and agmatine is converted to putrescine in a single enzymatic step.
33390	putrescine biosynthetic process from arginine via N-carbamoylputrescine	P	The chemical reactions and pathways resulting in the formation of putrescine, 1,4-diaminobutane, from other compounds, including arginine, via the intermediate N-carbamoylputrescine; in this pathway, arginine is converted to agmatine, and agmatine is converted to putrescine in two single enzymatic steps.
33391	chromatoid body	C	A ribonucleoprotein complex found in the cytoplasm of male germ cells, composed of exceedingly thin filaments that are consolidated into a compact mass or into dense strands of varying thickness that branch to form an irregular network. Contains mRNAs, miRNAs, and protein components involved in miRNA processing (such as Argonaute proteins and the endonuclease Dicer) and in RNA decay (such as the decapping enzyme DCP1a and GW182).
33393	homogalacturonan catabolic process	P	The chemical reactions and pathways resulting in the breakdown of homogalacturonan, a pectidic polymer, characterized by a backbone of 1,4-linked alpha-D-GalpA residues that can be methyl-esterified at C-6 and carry acetyl groups on O-2 and O-3.
33394	beta-alanine biosynthetic process via 1,3 diaminopropane	P	The chemical reactions and pathways resulting in the formation of beta-alanine via the intermediate 1,3 diaminopropane.
33395	beta-alanine biosynthetic process via 3-hydroxypropionate	P	The chemical reactions and pathways resulting in the formation of beta-alanine via the intermediate 3-hydroxypropionate.
33396	beta-alanine biosynthetic process via 3-ureidopropionate	P	The chemical reactions and pathways resulting in the formation of beta-alanine via the intermediate 3-ureidopropionate.
33397	zeatin metabolic process	P	The chemical reactions and pathways involving zeatin, 2-methyl-4-(9H-purin-6-ylamino)but-2-en-1-ol.
33398	zeatin biosynthetic process	P	The chemical reactions and pathways resulting in the formation of zeatin, 2-methyl-4-(9H-purin-6-ylamino)but-2-en-1-ol.
33399	cis-zeatin metabolic process	P	The chemical reactions and pathways involving cis-zeatin, (2Z)-2-methyl-4-(9H-purin-6-ylamino)but-2-en-1-ol.
33400	trans-zeatin metabolic process	P	The chemical reactions and pathways involving trans-zeatin, (2E)-2-methyl-4-(9H-purin-6-ylamino)but-2-en-1-ol.
33401	UUU codon-amino acid adaptor activity	F	A triplet codon-amino acid adaptor activity that recognizes a UUU codon.
33402	UUC codon-amino acid adaptor activity	F	A triplet codon-amino acid adaptor activity that recognizes a UUC codon.
33403	UUA codon-amino acid adaptor activity	F	A triplet codon-amino acid adaptor activity that recognizes a UUA codon.
33404	UUG codon-amino acid adaptor activity	F	A triplet codon-amino acid adaptor activity that recognizes a UUG codon.
33405	UCU codon-amino acid adaptor activity	F	A triplet codon-amino acid adaptor activity that recognizes a UCU codon.
33406	UCC codon-amino acid adaptor activity	F	A triplet codon-amino acid adaptor activity that recognizes a UCC codon.
33407	UCA codon-amino acid adaptor activity	F	A triplet codon-amino acid adaptor activity that recognizes a UCA codon.
33408	UCG codon-amino acid adaptor activity	F	A triplet codon-amino acid adaptor activity that recognizes a UCG codon.
33409	UAU codon-amino acid adaptor activity	F	A triplet codon-amino acid adaptor activity that recognizes a UAU codon.
33410	UAC codon-amino acid adaptor activity	F	A triplet codon-amino acid adaptor activity that recognizes a UAC codon.
33411	UAA codon-amino acid adaptor activity	F	A triplet codon-amino acid adaptor activity that recognizes a UAA codon.
33412	UAG codon-amino acid adaptor activity	F	A triplet codon-amino acid adaptor activity that recognizes a UAG codon.
33413	UGU codon-amino acid adaptor activity	F	A triplet codon-amino acid adaptor activity that recognizes a UGU codon.
33414	UGC codon-amino acid adaptor activity	F	A triplet codon-amino acid adaptor activity that recognizes a UGC codon.
33415	UGA codon-amino acid adaptor activity	F	A triplet codon-amino acid adaptor activity that recognizes a UGA codon.
33416	UGG codon-amino acid adaptor activity	F	A triplet codon-amino acid adaptor activity that recognizes a UGG codon.
33417	CUU codon-amino acid adaptor activity	F	A triplet codon-amino acid adaptor activity that recognizes a CUU codon.
33418	CUC codon-amino acid adaptor activity	F	A triplet codon-amino acid adaptor activity that recognizes a CUC codon.
33419	CUA codon-amino acid adaptor activity	F	A triplet codon-amino acid adaptor activity that recognizes a CUA codon.
33420	CUG codon-amino acid adaptor activity	F	A triplet codon-amino acid adaptor activity that recognizes a CUG codon.
33421	CCU codon-amino acid adaptor activity	F	A triplet codon-amino acid adaptor activity that recognizes a CCU codon.
33422	CCC codon-amino acid adaptor activity	F	A triplet codon-amino acid adaptor activity that recognizes a CCC codon.
33423	CCA codon-amino acid adaptor activity	F	A triplet codon-amino acid adaptor activity that recognizes a CCA codon.
33424	CCG codon-amino acid adaptor activity	F	A triplet codon-amino acid adaptor activity that recognizes a CCG codon.
33425	CAU codon-amino acid adaptor activity	F	A triplet codon-amino acid adaptor activity that recognizes a CAU codon.
33426	CAC codon-amino acid adaptor activity	F	A triplet codon-amino acid adaptor activity that recognizes a CAC codon.
33427	CAA codon-amino acid adaptor activity	F	A triplet codon-amino acid adaptor activity that recognizes a CAA codon.
33428	CAG codon-amino acid adaptor activity	F	A triplet codon-amino acid adaptor activity that recognizes a CAG codon.
33429	CGU codon-amino acid adaptor activity	F	A triplet codon-amino acid adaptor activity that recognizes a CGU codon.
33430	CGC codon-amino acid adaptor activity	F	A triplet codon-amino acid adaptor activity that recognizes a CGC codon.
33431	CGA codon-amino acid adaptor activity	F	A triplet codon-amino acid adaptor activity that recognizes a CGA codon.
33432	CGG codon-amino acid adaptor activity	F	A triplet codon-amino acid adaptor activity that recognizes a CGG codon.
33433	AUU codon-amino acid adaptor activity	F	A triplet codon-amino acid adaptor activity that recognizes an AUU codon.
33434	AUC codon-amino acid adaptor activity	F	A triplet codon-amino acid adaptor activity that recognizes an AUC codon.
33435	AUA codon-amino acid adaptor activity	F	A triplet codon-amino acid adaptor activity that recognizes an AUA codon.
33436	AUG codon-amino acid adaptor activity	F	A triplet codon-amino acid adaptor activity that recognizes an AUG codon.
33437	ACU codon-amino acid adaptor activity	F	A triplet codon-amino acid adaptor activity that recognizes an ACU codon.
33438	ACC codon-amino acid adaptor activity	F	A triplet codon-amino acid adaptor activity that recognizes an ACC codon.
33439	ACA codon-amino acid adaptor activity	F	A triplet codon-amino acid adaptor activity that recognizes an ACA codon.
33440	ACG codon-amino acid adaptor activity	F	A triplet codon-amino acid adaptor activity that recognizes an ACG codon.
33441	AAU codon-amino acid adaptor activity	F	A triplet codon-amino acid adaptor activity that recognizes an AAU codon.
33442	AAC codon-amino acid adaptor activity	F	A triplet codon-amino acid adaptor activity that recognizes an AAC codon.
33443	AAA codon-amino acid adaptor activity	F	A triplet codon-amino acid adaptor activity that recognizes an AAA codon.
33444	AAG codon-amino acid adaptor activity	F	A triplet codon-amino acid adaptor activity that recognizes an AAG codon.
33445	AGU codon-amino acid adaptor activity	F	A triplet codon-amino acid adaptor activity that recognizes an AGU codon.
33446	AGC codon-amino acid adaptor activity	F	A triplet codon-amino acid adaptor activity that recognizes an AGC codon.
33447	AGA codon-amino acid adaptor activity	F	A triplet codon-amino acid adaptor activity that recognizes an AGA codon.
33448	AGG codon-amino acid adaptor activity	F	A triplet codon-amino acid adaptor activity that recognizes an AGG codon.
33449	GUU codon-amino acid adaptor activity	F	A triplet codon-amino acid adaptor activity that recognizes a GUU codon.
33450	GUC codon-amino acid adaptor activity	F	A triplet codon-amino acid adaptor activity that recognizes a GUC codon.
33451	GUA codon-amino acid adaptor activity	F	A triplet codon-amino acid adaptor activity that recognizes a GUA codon.
33452	GUG codon-amino acid adaptor activity	F	A triplet codon-amino acid adaptor activity that recognizes a GUG codon.
33453	GCU codon-amino acid adaptor activity	F	A triplet codon-amino acid adaptor activity that recognizes a GCU codon.
33454	GCC codon-amino acid adaptor activity	F	A triplet codon-amino acid adaptor activity that recognizes a GCC codon.
33455	GCA codon-amino acid adaptor activity	F	A triplet codon-amino acid adaptor activity that recognizes a GCA codon.
33456	GCG codon-amino acid adaptor activity	F	A triplet codon-amino acid adaptor activity that recognizes a GCG codon.
33457	GAU codon-amino acid adaptor activity	F	A triplet codon-amino acid adaptor activity that recognizes a GAU codon.
33458	GAC codon-amino acid adaptor activity	F	A triplet codon-amino acid adaptor activity that recognizes a GAC codon.
33459	GAA codon-amino acid adaptor activity	F	A triplet codon-amino acid adaptor activity that recognizes a GAA codon.
33460	GAG codon-amino acid adaptor activity	F	A triplet codon-amino acid adaptor activity that recognizes a GAG codon.
33461	GGU codon-amino acid adaptor activity	F	A triplet codon-amino acid adaptor activity that recognizes a GGU codon.
33462	GGC codon-amino acid adaptor activity	F	A triplet codon-amino acid adaptor activity that recognizes a GGC codon.
33463	GGA codon-amino acid adaptor activity	F	A triplet codon-amino acid adaptor activity that recognizes a GGA codon.
33464	GGG codon-amino acid adaptor activity	F	A triplet codon-amino acid adaptor activity that recognizes a GGG codon.
33465	cis-zeatin biosynthetic process	P	The chemical reactions and pathways resulting in the formation of cis-zeatin, (2Z)-2-methyl-4-(9H-purin-6-ylamino)but-2-en-1-ol.
33466	trans-zeatin biosynthetic process	P	The chemical reactions and pathways resulting in the formation of trans-zeatin, (2E)-2-methyl-4-(9H-purin-6-ylamino)but-2-en-1-ol.
33467	CMP-keto-3-deoxy-D-manno-octulosonic acid metabolic process	P	The chemical reactions and pathways involving CMP-keto-3-deoxy-D-manno-octulosonic acid, a substance composed of the acidic sugar 3-deoxy-D-manno-octulosonic acid in glycosidic linkage with cytidine monophosphate.
33468	CMP-keto-3-deoxy-D-manno-octulosonic acid biosynthetic process	P	The chemical reactions and pathways resulting in the formation of CMP-keto-3-deoxy-D-manno-octulosonic acid, a substance composed of the acidic sugar 3-deoxy-D-manno-octulosonic acid in glycosidic linkage with cytidine monophosphate.
33469	gibberellin 12 metabolic process	P	The chemical reactions and pathways involving gibberellin 12, (1R,2S,3S,4R,8S,9S,12R)-4,8-dimethyl-13-methylidenetetracyclo[10.2.1.01,9.03,8]pentadecane-2,4-dicarboxylic acid 1meta,4a-dimethyl-8-methylidene-4aalpha,4bbeta-gibbane-1alpha,10beta-dicarboxylic acid.
33470	gibberellin 12 biosynthetic process	P	The chemical reactions and pathways resulting in the formation of gibberellin 12, (1R,2S,3S,4R,8S,9S,12R)-4,8-dimethyl-13-methylidenetetracyclo[10.2.1.01,9.03,8]pentadecane-2,4-dicarboxylic acid 1meta,4a-dimethyl-8-methylidene-4aalpha,4bbeta-gibbane-1alpha,10beta-dicarboxylic acid.
33471	GDP-L-galactose metabolic process	P	The chemical reactions and pathways involving GDP-L-galactose, a substance composed of L-galactose in glycosidic linkage with guanosine diphosphate.
33472	GDP-L-galactose biosynthetic process	P	The chemical reactions and pathways resulting in the formation of GDP-L-galactose, a substance composed of L-galactose in glycosidic linkage with guanosine diphosphate.
33473	indoleacetic acid conjugate metabolic process	P	The chemical reactions and pathways involving any indole-3-acetic acid conjugate, a form of indoleacetic acid covalently bound to another molecule.
33474	indoleacetic acid conjugate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of an indole-3-acetic acid conjugate, a form of indoleacetic acid covalently bound to another molecule.
33475	indoleacetic acid amide conjugate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of an indole-3-acetic acid amide conjugate, a form of indoleacetic acid covalently bound to an amino acid or polypeptide through an amide bond.
33476	indoleacetic acid ester conjugate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of an indole-3-acetic acid amide conjugate, a form of indoleacetic acid covalently bound to an a sugar or polyol through an ester bond.
33477	S-methylmethionine metabolic process	P	The chemical reactions and pathways involving S-methyl-methionine (SMM). SMM can be converted to methionine by donating a methyl group to homocysteine, and concurrent operation of this reaction and that mediated by MMT sets up the SMM cycle.
33478	UDP-rhamnose metabolic process	P	The chemical reactions and pathways involving UDP-L-rhamnose, a substance composed of rhamnose in glycosidic linkage with uridine diphosphate.
33479	UDP-D-galacturonate metabolic process	P	The chemical reactions and pathways involving UDP-D-galacturonate, a substance composed of galacturonic acid in glycosidic linkage with uridine diphosphate.
33480	UDP-D-galacturonate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of UDP-D-galacturonate, a substance composed of galacturonic acid in glycosidic linkage with uridine diphosphate.
33481	galacturonate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of galacturonate, the anion of galacturonic acid.
33482	D-galacturonate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of D-galacturonate, the D-enantiomer of galacturonate, the anion of galacturonic acid.
33483	gas homeostasis	P	A homeostatic process involved in the maintenance of an internal steady state of a gas within an organism or cell.
33484	nitric oxide homeostasis	P	A homeostatic process involved in the maintenance of an internal steady state of nitric oxide within an organism or cell.
33485	cyanidin 3-O-glucoside biosynthetic process	P	The chemical reactions and pathways resulting in the formation of cyanidin 3-O-glucoside, a basic anthocyanin responsible for red to magenta coloration of flowers and fruits.
33486	delphinidin 3-O-glucoside biosynthetic process	P	The chemical reactions and pathways resulting in the formation of delphinidin 3-O-glucoside, a basic, water-soluble anthocyanin responsible for blue coloration of flowers and fruits.
33487	pelargonidin 3-O-glucoside biosynthetic process	P	The chemical reactions and pathways resulting in the formation of pelargonidin 3-O-glucoside, a basic anthocyanin responsible for red to magenta coloration of flowers and fruits.
33488	cholesterol biosynthetic process via 24,25-dihydrolanosterol	P	The chemical reactions and pathways resulting in the formation of cholesterol, cholest-5-en-3 beta-ol, via the intermediate 24,25-dihydrolanosterol.
33489	cholesterol biosynthetic process via desmosterol	P	The chemical reactions and pathways resulting in the formation of cholesterol, cholest-5-en-3 beta-ol, via the intermediate desmosterol.
33490	cholesterol biosynthetic process via lathosterol	P	The chemical reactions and pathways resulting in the formation of cholesterol, cholest-5-en-3 beta-ol, via the intermediate lathosterol.
33491	coniferin metabolic process	P	The chemical reactions and pathways involving coniferin, 4-(3-hydroxyprop-1-en-1-yl)-2-methoxyphenyl beta-D-glucopyranoside.
33492	esculetin metabolic process	P	The chemical reactions and pathways involving esculetin, 6,7-dihydroxycoumarin.
33493	esculetin biosynthetic process	P	The chemical reactions and pathways resulting in the formation of esculetin, 6,7-dihydroxycoumarin.
33494	ferulate metabolic process	P	The chemical reactions and pathways involving ferulate, (2E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoate.
33495	ferulate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of ferulate, (2E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoate.
33496	sinapate metabolic process	P	The chemical reactions and pathways involving sinapate, (2E)-3-(4-hydroxy-3,5-dimethoxyphenyl)prop-2-enoate.
33497	sinapate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of sinapate, (2E)-3-(4-hydroxy-3,5-dimethoxyphenyl)prop-2-enoate.
33498	galactose catabolic process via D-galactonate	P	The chemical reactions and pathways resulting in the breakdown of galactose, via the intermediate D-galactonate.
33499	galactose catabolic process via UDP-galactose	P	The chemical reactions and pathways resulting in the breakdown of galactose, via the intermediate UDP-galactose.
33500	carbohydrate homeostasis	P	A homeostatic process involved in the maintenance of an internal steady state of a carbohydrate within an organism or cell.
33501	galactose homeostasis	P	A homeostatic process involved in the maintenance of an internal steady state of galactose within an organism or cell.
33502	cellular galactose homeostasis	P	A cellular homeostatic process involved in the maintenance of an internal steady state of galactose within a cell or between a cell and its external environment.
33503	HULC complex	C	A ubiquitin-conjugating enzyme complex that contains two RING finger proteins, which have ubiquitin ligase activity, in addition to a protein with ubiquitin-conjugating enzyme activity; catalyzes the ubiquitination of histone H2B at lysine 119 (or the equivalent residue). In Schizosaccharomyces the subunits are Rhp1, Brl2/Rfp1 and Brl1/Rfp2.
33504	floor plate development	P	The progression of the floor plate over time from its initial formation until its mature state.
33505	floor plate morphogenesis	P	The process in which the anatomical structure of the floor plate is generated and organized.
33506	glucosinolate biosynthetic process from homomethionine	P	The chemical reactions and pathways resulting in the formation of glucosinolates from other compounds including homomethionine.
33507	glucosinolate biosynthetic process from phenylalanine	P	The chemical reactions and pathways resulting in the formation of glucosinolates from other compounds including phenylalanine.
33508	glutamate catabolic process to butyrate	P	The chemical reactions and pathways resulting in the breakdown of glutamate into other compounds, including butyrate.
33509	glutamate catabolic process to propionate	P	The chemical reactions and pathways resulting in the breakdown of glutamate into other compounds, including propionate.
33510	luteolin metabolic process	P	The chemical reactions and pathways involving luteolin, 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4-one.
33511	luteolin biosynthetic process	P	The chemical reactions and pathways resulting in the formation of luteolin, 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4-one.
33512	L-lysine catabolic process to acetyl-CoA via saccharopine	P	The chemical reactions and pathways resulting in the breakdown of L-lysine into other compounds, including acetyl-CoA, via the intermediate saccharopine.
33513	L-lysine catabolic process to acetyl-CoA via 5-aminopentanamide	P	The chemical reactions and pathways resulting in the breakdown of L-lysine into other compounds, including acetyl-CoA, via the intermediate 5-aminopentanamide.
33514	L-lysine catabolic process to acetyl-CoA via L-pipecolate	P	The chemical reactions and pathways resulting in the breakdown of L-lysine into other compounds, including acetyl-CoA, via the intermediate L-pipecolate.
33515	L-lysine catabolic process using lysine 6-aminotransferase	P	The chemical reactions and pathways resulting in the breakdown of L-lysine into other compounds, including alpha-aminoadipate; in this pathway, L-lysine is converted to 2-aminoadipate-6-semialdehyde by lysine 6-aminotransferase.
33516	L-methionine biosynthetic process from homoserine via O-phospho-L-homoserine and cystathionine	P	The chemical reactions and pathways resulting in the formation of L-methionine from other compounds, including homoserine, via the intermediates O-phospho-L-homoserine and cystathionine.
33517	myo-inositol hexakisphosphate metabolic process	P	The chemical reactions and pathways involving phytic acid, myo-inositol hexakisphosphate, a regulator of intracellular signaling, a highly abundant animal anti-nutrient and a phosphate and mineral storage compound in plant seeds.
33518	myo-inositol hexakisphosphate dephosphorylation	P	The process of removing one or more phosphate group from myo-inositol hexakisphosphate.
33519	phytyl diphosphate metabolic process	P	The chemical reactions and pathways involving phytyl diphosphate, (2E)-3,7,11,15-tetramethylhexadec-2-en-1-yl trihydrogen diphosphate.
33520	phytol biosynthetic process	P	The chemical reactions and pathways resulting in the formation of phytol, (2E,7R,11R)-3,7,11,15-tetramethylhexadec-2-en-1-ol.
33521	phytyl diphosphate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of phytyl diphosphate, (2E)-3,7,11,15-tetramethylhexadec-2-en-1-yl trihydrogen diphosphate.
33522	histone H2A ubiquitination	P	The modification of histone H2A by addition of one or more ubiquitin groups.
33523	histone H2B ubiquitination	P	The modification of histone H2B by addition of ubiquitin groups.
33524	sinapate ester metabolic process	P	The chemical reactions and pathways involving ester derivatives of sinapate, (2E)-3-(4-hydroxy-3,5-dimethoxyphenyl)prop-2-enoate.
33525	sinapate ester biosynthetic process	P	The chemical reactions and pathways resulting in the formation of ester derivates of sinapate, (2E)-3-(4-hydroxy-3,5-dimethoxyphenyl)prop-2-enoate.
33526	tetrapyrrole biosynthetic process from glutamate	P	The chemical reactions and pathways leading to the formation of tetrapyrroles, natural pigments containing four pyrrole rings joined by one-carbon units linking position 2 of one pyrrole ring to position 5 of the next, from other compounds, including L-glutamate.
33527	tetrapyrrole biosynthetic process from glycine and succinyl-CoA	P	The chemical reactions and pathways leading to the formation of tetrapyrroles, natural pigments containing four pyrrole rings joined by one-carbon units linking position 2 of one pyrrole ring to position 5 of the next, from other compounds, including glycine and succinyl-CoA.
33528	S-methylmethionine cycle	P	A cyclic series of interconversions involving S-methyl-L-methionine, S-adenosyl-L-homocysteine, S-adenosyl-L-methionine, L-homocysteine, and L-methionine. Converts the methionine group of adenosylmethionine back to free methionine, and may serve regulate the cellular adenosylmethionine level.
33529	raffinose biosynthetic process	P	The chemical reactions and pathways resulting in the formation of raffinose, the trisaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside.
33530	raffinose metabolic process	P	The chemical reactions and pathways involving raffinose, the trisaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside.
33531	stachyose metabolic process	P	The chemical reactions and pathways involving stachyose, the tetrasaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside.
33532	stachyose biosynthetic process	P	The chemical reactions and pathways resulting in the formation of stachyose, the tetrasaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside.
33533	verbascose metabolic process	P	The chemical reactions and pathways involving verbascose, the pentasaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside.
33534	verbascose biosynthetic process	P	The chemical reactions and pathways resulting in the formation of verbascose, the pentasaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside.
33535	ajugose metabolic process	P	The chemical reactions and pathways involving ajugose, the hexasaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside.
33536	ajugose biosynthetic process	P	The chemical reactions and pathways resulting in the formation of ajugose, the hexasaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside.
33537	ajugose biosynthetic process using galactinol:raffinose galactosyltransferase	P	The chemical reactions and pathways resulting in the formation of ajugose, the hexasaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside, by a pathway in which galactinol:raffinose galactosyltransferase catalyzes chain elongation by transferring the alpha-galactosyl residue of galactinol to the oligosaccharide.
33538	ajugose biosynthetic process using galactan:galactan galactosyltransferase	P	The chemical reactions and pathways resulting in the formation of ajugose, the hexasaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside, by a pathway in which galactan:galactan galactosyltransferase catalyzes chain elongation by transferring the alpha-galactosyl residue of one raffinose-family oligosaccharide to another.
33539	fatty acid beta-oxidation using acyl-CoA dehydrogenase	P	A fatty acid beta-oxidation pathway in which the initial step of each oxidation cycle, which converts an acyl-CoA to a trans-2-enoyl-CoA, is catalyzed by acyl-CoA dehydrogenase; the electrons removed by oxidation pass through the respiratory chain to oxygen and leave H2O as the product. Fatty acid beta-oxidation begins with the addition of coenzyme A to a fatty acid, and ends when only two or three carbons remain (as acetyl-CoA or propionyl-CoA respectively).
33540	fatty acid beta-oxidation using acyl-CoA oxidase	P	A fatty acid beta-oxidation pathway in which the initial step, which converts an acyl-CoA to a trans-2-enoyl-CoA, is catalyzed by acyl-CoA oxidase; the electrons removed by oxidation pass directly to oxygen and produce hydrogen peroxide, which is cleaved by peroxisomal catalases. Fatty acid beta-oxidation begins with the addition of coenzyme A to a fatty acid, and ends when only two or three carbons remain (as acetyl-CoA or propionyl-CoA respectively).
33541	fatty acid beta-oxidation, unsaturated, odd number	P	A fatty acid beta-oxidation pathway by which fatty acids having cis-double bonds on odd-numbered carbons are degraded. In this pathway, a cis-3-enoyl-CoA is generated by the core beta-oxidation pathway, and then converted to a trans-2-enoyl-CoA, which can return to the core beta-oxidation pathway for complete degradation. Fatty acid beta-oxidation begins with the addition of coenzyme A to a fatty acid, and ends when only two or three carbons remain (as acetyl-CoA or propionyl-CoA respectively).
33542	fatty acid beta-oxidation, unsaturated, even number	P	A fatty acid beta-oxidation pathway by which fatty acids having cis-double bonds on even-numbered carbons are degraded. Fatty acid beta-oxidation begins with the addition of coenzyme A to a fatty acid, and ends when only two or three carbons remain (as acetyl-CoA or propionyl-CoA respectively).
33543	fatty acid beta-oxidation, unsaturated, even number, reductase/isomerase pathway	P	A fatty acid beta-oxidation pathway by which fatty acids having cis-double bonds on even-numbered carbons are degraded. In this pathway, the intermediate 2,4-dienoyl-CoA is converted to trans-2-enoyl-CoA by 2,4-dienoyl-CoA reductase and delta3-delta2-enoyl-CoA isomerase; trans-2-enoyl-CoA returns to the core beta-oxidation pathway for further degradation. Fatty acid beta-oxidation begins with the addition of coenzyme A to a fatty acid, and ends when only two or three carbons remain (as acetyl-CoA or propionyl-CoA respectively).
33544	fatty acid beta-oxidation, unsaturated, even number, epimerase pathway	P	A fatty acid beta-oxidation pathway by which fatty acids having cis-double bonds on even-numbered carbons are degraded. In this pathway, the intermediate 2,4-dienoyl-CoA is converted to cis-2-enoyl-CoA through one more cycle of the core beta-oxidation pathway. Cis-2-enoyl-CoA cannot be completely degraded via the core beta-oxidation pathway because hydratation of cis-2-enoyl-CoA yields D-3-hydroxyacyl-CoA, which is not a substrate for 3-hydroxylacyl-CoA dehydrogenase. Cis-2-enoyl-CoA must enter the so-called epimerase pathway, which involves converting D-3-hydroxyacyl-CoA to L-3-hydroxyacyl-CoA by 3-hydroxylacyl-CoA epimerase or by two stereo-specific enoyl-CoA hydratases. L-3-hydroxyacyl-CoA then returns to the core beta-oxidation pathway. Fatty acid beta-oxidation begins with the addition of coenzyme A to a fatty acid, and ends when only two or three carbons remain (as acetyl-CoA or propionyl-CoA respectively).
33545	myo-inositol hexakisphosphate biosynthetic process, lipid-dependent	P	The chemical reactions and pathways resulting in the formation of 1D-myo-inositol 1,2,3,4,5,6-hexakisphosphate, phytate, by a pathway using inositol 1,4,5-trisphosphate produced from phosphatidylinositol 4,5-biphosphate hydrolysis by phospholipase C.
33546	myo-inositol hexakisphosphate biosynthetic process, via inositol 1,3,4-trisphosphate	P	The chemical reactions and pathways resulting in the formation of 1D-myo-inositol 1,2,3,4,5,6-hexakisphosphate, phytate, by a pathway using inositol 1,4,5-trisphosphate produced from phosphatidylinositol 4,5-biphosphate hydrolysis by phospholipase C; in this pathway, inositol 1,4,5-trisphosphate is first converted to inositol 1,3,4-trisphosphate, and then phosphorylated further.
33548	myo-inositol hexakisphosphate biosynthetic process, lipid-independent	P	The chemical reactions and pathways resulting in the formation of phytic acid, myo-inositol hexakisphosphate, by the successively phosphorylation of myo-inositol or an inositol trisphosphate; the inositol trisphosphates that may be used by this pathway are inositol 3,4,5-trisphosphate and inositol 3,4,6trisphosphate.
33549	MAP kinase phosphatase activity	F	Catalysis of the reaction: a phosphorylated MAP kinase + H2O = a MAP kinase + phosphate.
33550	MAP kinase tyrosine phosphatase activity	F	Catalysis of the reaction: MAP kinase tyrosine phosphate + H2O = MAP kinase tyrosine + phosphate.
33551	monopolin complex	C	A protein complex required for clamping microtubule binding sites, ensuring orientation of sister kinetochores to the same pole (mono-orientation) during meiosis I. In the yeast S. cerevisiae this complex consists of Csm1p, Lrs4p, Hrr25p and Mam1p; in S. pombe Psc1 and Mde4 have been identified as subunits.
33552	response to vitamin B3	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin B3 stimulus.
33553	rDNA heterochromatin	C	A region of heterochromatin located at the rDNA repeats in a chromosome.
33554	cellular response to stress	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).
33555	multicellular organismal response to stress	P	Any process that results in a change in state or activity of a multicellular organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).
33556	dolichyl pyrophosphate Man7GlcNAc2 alpha-1,3-glucosyltransferase activity	F	Catalysis of the addition of a glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation; the transfer of glucose from dolichyl phosphate glucose (Dol-P-Glc) on to the lipid-linked oligosaccharide Man(7)GlcNAc(2)-PP-Dol.
33557	Slx1-Slx4 complex	C	A heterodimeric protein complex that possesses an endonuclease activity that specifically cleaves certain types of branched DNA structures; because such structures often form during the replication ribosomal DNA (rDNA) repeats, the complex plays a role in the maintenance of rDNA. The subunits are known as Slx1 and Slx 4 in budding and fission yeasts, and are conserved in eukaryotes.
33558	protein deacetylase activity	F	Catalysis of the hydrolysis of an acetyl group or groups from a protein substrate.
33559	unsaturated fatty acid metabolic process	P	The chemical reactions and pathways involving an unsaturated fatty acid, any fatty acid containing one or more double bonds between carbon atoms.
33560	folate reductase activity	F	Catalysis of the reaction: 7,8-dihydrofolate + NADP+ = folate + NADPH + H+.
33561	regulation of water loss via skin	P	A process that modulates the rate or extent of water loss from an organism via the skin.
33562	co-transcriptional gene silencing by RNA interference machinery	P	A process in which the RNAi machinery mediates the degradation of nascent transcripts in association with chromatin.
33563	dorsal/ventral axon guidance	P	The process in which the migration of an axon growth cone is directed to a specific target site along the dorsal-ventral body axis in response to a combination of attractive and repulsive cues. The dorsal/ventral axis is defined by a line that runs orthogonal to both the anterior/posterior and left/right axes. The dorsal end is defined by the upper or back side of an organism. The ventral end is defined by the lower or front side of an organism.
33564	anterior/posterior axon guidance	P	The process in which the migration of an axon growth cone is directed to a specific target site along the anterior-posterior body axis in response to a combination of attractive and repulsive cues. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism.
33565	ESCRT-0 complex	C	A protein complex required for the recycling of Golgi proteins, formation of lumenal membranes and sorting of ubiquitinated proteins into those membranes. This complex includes Vps1p and Hse1p in yeast and the Hrs and STAM proteins in mammals.
33566	gamma-tubulin complex localization	P	Any process in which a gamma-tubulin complex is transported to, or maintained in, a specific location.
33567	DNA replication, Okazaki fragment processing	P	The DNA metabolic process, occurring during lagging strand synthesis, by which RNA primers are removed from Okazaki fragments, the resulting gaps filled by DNA polymerization, and the ends ligated to form a continuous strand.
33568	lactoferrin receptor activity	F	Combining with lactoferrin and delivering lactoferrin into the cell via endocytosis. Lactoferrin is an iron-binding glycoprotein which binds ferric iron most efficiently at low pH.
33569	lactoferrin transmembrane transporter activity	F	Catalysis of the transfer of lactoferrin from one side of a membrane to the other.
33570	transferrin transmembrane transporter activity	F	Enables the transfer of transferrin from one side of a membrane to the other.
33571	lactoferrin transport	P	The directed movement of lactoferrin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
33572	transferrin transport	P	The directed movement of transferrin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
33573	high-affinity iron permease complex	C	A protein complex composed of a multicopper ferroxidase that oxidizes Fe(II) to Fe(III), and a ferric iron permease that transports the produced Fe(III) into the cell. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.
33574	response to testosterone	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a testosterone stimulus.
33575	protein glycosylation at cell surface	P	The addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid at the surface of a cell.
33576	protein glycosylation in cytosol	P	The addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid in the cytosol.
33577	protein glycosylation in endoplasmic reticulum	P	The addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid in the endoplasmic reticulum.
33578	protein glycosylation in Golgi	P	The addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid in any compartment of the Golgi apparatus.
33579	protein galactosylation in endoplasmic reticulum	P	The addition of a galactose unit to a protein amino acid in the endoplasmic reticulum.
33580	protein galactosylation at cell surface	P	The addition of a galactose unit to a protein amino acid at the surface of a cell.
33581	protein galactosylation in Golgi	P	The addition of a galactose unit to a protein amino acid in any compartment of the Golgi apparatus.
33582	protein galactosylation in cytosol	P	The addition of a galactose unit to a protein amino acid in the cytosol.
33583	rhabdomere membrane	C	The portion of the plasma membrane surrounding the rhabdomere.
33584	tyrosine biosynthetic process from chorismate via L-arogenate	P	The chemical reactions and pathways resulting in the formation of tyrosine from other compounds, including chorismate, via the intermediate L-arogenate.
33585	L-phenylalanine biosynthetic process from chorismate via phenylpyruvate	P	The chemical reactions and pathways resulting in the formation of L-phenylalanine from other compounds, including chorismate, via the intermediate phenylpyruvate.
33586	L-phenylalanine biosynthetic process from chorismate via L-arogenate	P	The chemical reactions and pathways resulting in the formation of L-phenylalanine from other compounds, including chorismate, via the intermediate L-arogenate.
33587	shikimate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of shikimate, (3R,4S,5R)--3,4,5-trihydroxycyclohex-1-ene-1-carboxylate, the anion of shikimic acid.
33588	Elongator holoenzyme complex	C	A heterohexameric protein complex that is involved in modification of wobble nucleosides in tRNA. The complex can associate physically with hyperphosphorylated RNA polymerase II; it contains two discrete heterotrimeric subcomplexes.
33590	response to cobalamin	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cobalamin (vitamin B12) stimulus.
33591	response to L-ascorbic acid	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an L-ascorbic acid (vitamin C) stimulus.
33592	RNA strand annealing activity	F	Facilitates the base-pairing of complementary single-stranded RNA.
33593	BRCA2-MAGE-D1 complex	C	A heterodimeric protein complex formed of BRCA2 and MAGE-D1; may mediate the synergistic activities of the two proteins in regulating cell growth.
33594	response to hydroxyisoflavone	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydroxyisoflavone stimulus.
33595	response to genistein	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a genistein stimulus.
33596	TSC1-TSC2 complex	C	A protein complex consisting of at least tumerin and hamartin; its formation may regulate hamartin homomultimer formation. The complex acts as a GTPase activating protein (GAP) for the small GTPase (Rheb), and inhibits the TOR signaling pathway.
33597	mitotic checkpoint complex	C	A multiprotein complex that functions as a mitotic checkpoint inhibitor of the anaphase-promoting complex/cyclosome (APC/C). In budding yeast this complex consists of Mad2p, Mad3p, Bub3p and Cdc20p, and in mammalian cells it consists of MAD2, BUBR1, BUB3, and CDC20.
33598	mammary gland epithelial cell proliferation	P	The multiplication or reproduction of mammary gland epithelial cells, resulting in the expansion of a cell population. Mammary gland epithelial cells make up the covering of surfaces of the mammary gland. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk.
33599	regulation of mammary gland epithelial cell proliferation	P	Any process that modulates the frequency, rate or extent of mammary gland epithelial cell proliferation.
33600	negative regulation of mammary gland epithelial cell proliferation	P	Any process that stops, prevents or reduces the rate or extent of mammary gland epithelial cell proliferation.
33601	positive regulation of mammary gland epithelial cell proliferation	P	Any process that activates or increases the rate or extent of mammary gland epithelial cell proliferation.
33602	negative regulation of dopamine secretion	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of dopamine.
33603	positive regulation of dopamine secretion	P	Any process that activates or increases the frequency, rate or extent of the regulated release of dopamine.
33604	negative regulation of catecholamine secretion	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a catecholamine.
33605	positive regulation of catecholamine secretion	P	Any process that activates or increases the frequency, rate or extent of the regulated release of a catecholamine.
33606	chemokine receptor transport within lipid bilayer	P	The directed movement of a chemokine receptor within a lipid bilayer.
33607	SOD1-Bcl-2 complex	C	A heterodimeric protein complex formed of superoxide dismutase 1 and Bcl-2. Complex formation is thought to link superoxide dismutase to an apoptotic pathway.
33608	formyl-CoA transferase activity	F	Catalysis of the reaction: formyl-CoA + oxalate = formate + oxalyl-CoA.
33609	oxalate metabolic process	P	The chemical reactions and pathways involving oxalate, the organic acid ethanedioate.
33610	oxalate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of oxalate, the organic acid ethanedioate.
33611	oxalate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of oxalate, the organic acid ethanedioate.
33612	receptor serine/threonine kinase binding	F	Interacting selectively and non-covalently with a receptor that possesses protein serine/threonine kinase activity.
33613	activating transcription factor binding	F	Interacting selectively and non-covalently with an activating transcription factor, any protein whose activity is required to initiate or upregulate transcription.
33614	chloroplast proton-transporting ATP synthase complex assembly	P	The aggregation, arrangement and bonding together of a proton-transporting ATP synthase in the chloroplast thylakoid membrane.
33615	mitochondrial proton-transporting ATP synthase complex assembly	P	The aggregation, arrangement and bonding together of a proton-transporting ATP synthase in the mitochondrial inner membrane.
33616	plasma membrane proton-transporting ATP synthase complex assembly	P	The aggregation, arrangement and bonding together of a proton-transporting ATP synthase in the plasma membrane.
33617	mitochondrial respiratory chain complex IV assembly	P	The aggregation, arrangement and bonding together of a set of components to form respiratory chain complex IV (also known as cytochrome c oxidase) in the mitochondrial inner membrane.
33618	plasma membrane respiratory chain complex IV assembly	P	The aggregation, arrangement and bonding together of a set of components to form respiratory chain complex IV (also known as cytochrome c oxidase) in the plasma membrane.
33619	membrane protein proteolysis	P	The proteolytic cleavage of a transmembrane protein leading to the release of its intracellular or ecto-domains.
33620	Mei2 nuclear dot complex	C	A ribonucleoprotein complex that forms during meiotic prophase in a fixed position in the horsetail nucleus; contains Mei2 and meiRNA. May play a role in the progression of meiosis I.
33621	nuclear-transcribed mRNA catabolic process, meiosis-specific transcripts	P	The chemical reactions and pathways resulting in the selective degradation of meiosis-specific transcripts during vegetative growth, by a mechanism that requires determinant of selective removal (DSR) sequences in the targeted mRNAs and involves a YTH family protein.
33622	integrin activation	P	The aggregation, arrangement and bonding together of an integrin, a heterodimeric adhesion receptor formed by the non-covalent association of particular alpha and beta subunits, that lead to the increased affinity of the integrin for its extracellular ligands.
33623	regulation of integrin activation	P	Any process that modulates the frequency, rate, or extent of integrin activation.
33624	negative regulation of integrin activation	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of integrin activation.
33625	positive regulation of integrin activation	P	Any process that activates or increases the frequency, rate, or extent of integrin activation.
33626	positive regulation of integrin activation by cell surface receptor linked signal transduction	P	Any series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell that lead to the increased affinity of an integrin, a heterodimeric adhesion receptor formed by the non-covalent association of particular alpha and beta subunits, for its extracellular ligands.
33627	cell adhesion mediated by integrin	P	The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via an integrin, a heterodimeric adhesion receptor formed by the non-covalent association of particular alpha and beta subunits.
33628	regulation of cell adhesion mediated by integrin	P	Any process that modulates the frequency, rate, or extent of cell adhesion mediated by integrin.
33629	negative regulation of cell adhesion mediated by integrin	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of cell adhesion mediated by integrin.
33630	positive regulation of cell adhesion mediated by integrin	P	Any process that activates or increases the frequency, rate, or extent of cell adhesion mediated by integrin.
33631	cell-cell adhesion mediated by integrin	P	The attachment of one cell to another cell via an integrin, a heterodimeric adhesion receptor formed by the non-covalent association of particular alpha and beta subunits.
33632	regulation of cell-cell adhesion mediated by integrin	P	Any process that modulates the frequency, rate, or extent of cell-cell adhesion mediated by integrin.
33633	negative regulation of cell-cell adhesion mediated by integrin	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of cell-cell adhesion mediated by integrin.
33634	positive regulation of cell-cell adhesion mediated by integrin	P	Any process that activates or increases the frequency, rate, or extent of cell-cell adhesion mediated by integrin.
33635	modulation by symbiont of host response to abiotic stimulus	P	Any process in which an organism modulates a change in the state or activity of a host cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abiotic (non-living) stimulus. The host is defined as the larger of the organisms involved in a symbiotic interaction.
33636	modulation by symbiont of host response to temperature stimulus	P	Any process in which an organism modulates a change in state or activity of a host cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a temperature stimulus. The host is defined as the larger of the organisms involved in a symbiotic interaction.
33637	modulation by symbiont of host response to cold	P	Any process in which an organism modulates a change in state or activity of a host cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cold stimulus, a temperature stimulus below the optimal temperature for that organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
33638	modulation by symbiont of host response to heat	P	Any process in which an organism modulates a change in state or activity of a host cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
33639	modulation by symbiont of host response to water	P	Any process in which an organism modulates a change in state or activity of a host cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a water stimulus. The host is defined as the larger of the organisms involved in a symbiotic interaction.
33640	modulation by symbiont of host response to osmotic stress	P	Any process in which an organism modulates a change in state or activity of a host cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell. The host is defined as the larger of the organisms involved in a symbiotic interaction.
33641	modulation by symbiont of host response to pH	P	Any process in which an organism modulates a change in state or activity of a host cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus. The host is defined as the larger of the organisms involved in a symbiotic interaction.
33642	modulation by symbiont of host response to gravitational stimulus	P	Any process in which an organism modulates a change in state or activity of a host cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gravitational stimulus. The host is defined as the larger of the organisms involved in a symbiotic interaction.
33643	host cell part	C	Any constituent part of a host cell. The host is defined as the larger of the organisms involved in a symbiotic interaction.
33644	host cell membrane	C	Double layer of lipid molecules as it encloses host cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins. The host is defined as the larger of the organisms involved in a symbiotic interaction.
33645	host cell endomembrane system	C	A collection of membranous structures involved in transport within the host cell. The main components of the endomembrane system are endoplasmic reticulum, Golgi bodies, vesicles, cell membrane and nuclear envelope. Members of the endomembrane system pass materials through each other or though the use of vesicles. The host is defined as the larger of the organisms involved in a symbiotic interaction.
33646	host intracellular part	C	Any constituent part of the living contents of a host cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm. The host is defined as the larger of the organisms involved in a symbiotic interaction.
33647	host intracellular organelle	C	Organized structure of distinctive morphology and function, occurring within the host cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane. The host is defined as the larger of the organisms involved in a symbiotic interaction.
33648	host intracellular membrane-bounded organelle	C	Organized structure of distinctive morphology and function, as found in host cells, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane. The host is defined as the larger of the organisms involved in a symbiotic interaction.
33650	host cell mitochondrion	C	A semiautonomous, self replicating organelle as found in host cells that occurs in varying numbers, shapes, and sizes in the cell cytoplasm. The host is defined as the larger of the organisms involved in a symbiotic interaction.
33651	host cell plastid	C	Any member of a family of organelles as found in the cytoplasm of host cells, which are membrane-bounded and contain DNA. The host is defined as the larger of the organisms involved in a symbiotic interaction.
33652	host cell chloroplast	C	A chlorophyll-containing plastid as found within host cells with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma. The host is defined as the larger of the organisms involved in a symbiotic interaction.
33653	host cell chloroplast part	C	Any constituent part of a chloroplast as it is found in host cells and which are a chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma. The host is defined as the larger of the organisms involved in a symbiotic interaction.
33654	host cell chloroplast thylakoid membrane	C	Any sac-like membranous structures (cisternae) in a chloroplast found in host cells, combined into stacks (grana) and present singly in the stroma (stroma thylakoids or frets) as interconnections between grana. The host is defined as the larger of the organisms involved in a symbiotic interaction.
33655	host cell cytoplasm part	C	Any constituent part of the host cell cytoplasm, all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. The host is defined as the larger of the organisms involved in a symbiotic interaction.
33656	modification by symbiont of host chloroplast	P	The process in which an organism effects a change in the structure or function of host cell chloroplasts. The host is defined as the larger of the organisms involved in a symbiotic interaction.
33657	modification by symbiont of host chloroplast part	P	The process in which an organism effects a change in the structure or function of a component of the host cell chloroplast. The host is defined as the larger of the organisms involved in a symbiotic interaction.
33658	modification by symbiont of host chloroplast thylakoid	P	The process in which an organism effects a change in the structure or function of the host cell chloroplast thylakoid. The host is defined as the larger of the organisms involved in a symbiotic interaction.
33659	modification by symbiont of host mitochondrion	P	The process in which an organism effects a change in the structure or function of host cell mitochondria. The host is defined as the larger of the organisms involved in a symbiotic interaction.
33660	negative regulation by symbiont of host resistance gene-dependent defense response	P	Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of the resistance gene-dependent defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
33661	negative regulation by symbiont of defense-related host reactive oxygen species production	P	Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of the production of reactive oxygen species as part of the defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
33662	modulation by symbiont of host defense-related protein level	P	The alternation by a symbiont of the levels of defense-related proteins in its host. The host is defined as the larger of the organisms involved in a symbiotic interaction.
33663	negative regulation by symbiont of host defense-related protein level	P	Any process in which the symbiont stops or reduces of the levels of defense-related proteins in its host. The host is defined as the larger of the organisms involved in a symbiotic interaction.
33664	positive regulation by symbiont of host defense-related protein level	P	Any process in which the symbiont activates, maintains or increases levels of defense-related proteins in its host. The host is defined as the larger of the organisms involved in a symbiotic interaction.
33668	negative regulation by symbiont of host apoptotic process	P	Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of programmed cell death in the host, where programmed cell death proceeds by apoptosis. The host is defined as the larger of the organisms involved in a symbiotic interaction.
33670	regulation of NAD+ kinase activity	P	Any process that modulates the frequency, rate or extent of NAD kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to an NAD molecule.
33671	negative regulation of NAD+ kinase activity	P	Any process that stops, prevents, or reduces the frequency, rate or extent of NAD kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to an NAD molecule.
33672	positive regulation of NAD+ kinase activity	P	Any process that activates or increases the frequency, rate or extent of NAD kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to an NAD molecule.
33673	negative regulation of kinase activity	P	Any process that stops, prevents, or reduces the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule.
33674	positive regulation of kinase activity	P	Any process that activates or increases the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule.
33675	pericanalicular vesicle	C	A membrane-bounded vesicle found near the apical, or pericanalicular, membrane of a hepatocyte; contains proteins involved in bile salt transport and other fluid and solute transport processes.
33676	double-stranded DNA-dependent ATPase activity	F	Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction requires the presence of double-stranded DNA, and it drives another reaction.
33677	DNA/RNA helicase activity	F	Catalysis of the reaction: NTP + H2O = NDP + phosphate; this reaction drives the unwinding of a DNA/RNA duplex, i.e. a double helix in which a strand of DNA pairs with a complementary strand of RNA.
33678	5'-3' DNA/RNA helicase activity	F	Catalysis of the unwinding of a DNA/RNA duplex in the direction 5' to 3'.
33679	3'-5' DNA/RNA helicase activity	F	Catalysis of the unwinding of a DNA/RNA duplex in the direction 3' to 5'.
33680	ATP-dependent DNA/RNA helicase activity	F	Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction drives the unwinding of a DNA/RNA duplex.
33681	ATP-dependent 3'-5' DNA/RNA helicase activity	F	Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction drives the unwinding of a DNA/RNA duplex in the direction 3' to 5'.
33682	ATP-dependent 5'-3' DNA/RNA helicase activity	F	Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction drives the unwinding of a DNA/RNA duplex in the direction 5' to 3'.
33683	nucleotide-excision repair, DNA incision	P	A process that results in the endonucleolytic cleavage of the damaged strand of DNA. The incision occurs at the junction of single-stranded DNA and double-stranded DNA that is formed when the DNA duplex is unwound.
33684	regulation of luteinizing hormone secretion	P	Any process that modulates the frequency, rate or extent of the regulated release of luteinizing hormone.
33685	negative regulation of luteinizing hormone secretion	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of luteinizing hormone.
33686	positive regulation of luteinizing hormone secretion	P	Any process that activates or increases the frequency, rate or extent of the regulated release of luteinizing hormone.
33687	osteoblast proliferation	P	The multiplication or reproduction of osteoblasts, resulting in the expansion of an osteoblast cell population. An osteoblast is a bone-forming cell which secretes an extracellular matrix. Hydroxyapatite crystals are then deposited into the matrix to form bone.
33688	regulation of osteoblast proliferation	P	Any process that modulates the frequency, rate or extent of osteoblast proliferation.
33689	negative regulation of osteoblast proliferation	P	Any process that stops, prevents or reduces the rate or extent of osteoblast proliferation.
33690	positive regulation of osteoblast proliferation	P	Any process that activates or increases the rate or extent of osteoblast proliferation.
33691	sialic acid binding	F	Interacting selectively and non-covalently with sialic acid, any of a variety of N- or O- substituted derivatives of neuraminic acid, a nine carbon monosaccharide. Sialic acids often occur in polysaccharides, glycoproteins, and glycolipids in animals and bacteria.
33692	cellular polysaccharide biosynthetic process	P	The chemical reactions and pathways resulting in the formation of polysaccharides, polymers of many (typically more than 10) monosaccharide residues linked glycosidically, occurring at the level of an individual cell.
33693	neurofilament bundle assembly	P	The assembly of neurofilaments into bundles, in which the filaments are longitudinally oriented, with numerous crossbridges between them. Neurofilament bundles may be cross-linked to each other, to membrane-bounded organelles or other cytoskeletal structures such as microtubules.
33694	oxidoreductase activity, acting on the CH-NH group of donors, iron-sulfur protein as acceptor	F	Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH group acts as a hydrogen or electron donor and reduces an iron-sulfur protein.
33695	oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor	F	Catalysis of an oxidation-reduction (redox) reaction in which a CH2 group acts as a hydrogen or electron donor and reduces a quinone or similar acceptor molecule.
33696	negative regulation of extent of heterochromatin assembly	P	Any process that reduces the extent of heterochromatin formation; reduces the size of a chromosomal region converted to heterochromatin.
33697	positive regulation of extent of heterochromatin assembly	P	Any process that increases the extent of heterochromatin formation; increases the size of a chromosomal region converted to heterochromatin.
33698	Rpd3L complex	C	A histone deacetylase complex which deacetylates histones across gene coding regions. Composed of a catalytic histone deacetylase subunit, an Sds-3 family protein, a SIN3 family co-repressor, a WD repeat protein, and a zf- PHD finger (Clr6, Sds3, Pst1, Prw1, Png2 in Schizosaccharomyces pombe; Rpd3p, Sin3p, Ume1p, Pho23p, Sap30p, Sds3p, Cti6p, Rxt2p, Rxt3p, Dep1p, Ume6p and Ash1p in Saccharomyces cerevisiae).
33699	DNA 5'-adenosine monophosphate hydrolase activity	F	Catalysis of the reaction: 5'-AMP-DNA + H2O = AMP + DNA; nucleophilic release of a covalently linked adenylate residue from a DNA strand, leaving a 5' phosphate terminus.
33700	phospholipid efflux	P	The directed movement of a phospholipid out of a cell or organelle.
33701	dTDP-galactose 6-dehydrogenase activity	F	Catalysis of the reaction: dTDP-D-galactose + 2 NADP+ + H2O = dTDP-D-galacturonate + 2 NADPH + 2 H+.
33702	(+)-trans-carveol dehydrogenase activity	F	Catalysis of the reaction: (1R,5S)-carveol + NAD(+) = (S)-carvone + H(+) + NADH.
33703	3beta-hydroxy-5beta-steroid dehydrogenase activity	F	Catalysis of the reaction: 3beta-hydroxy-5beta-pregnane-20-one + NADP(+) = 5beta-pregnan-3,20-dione + H(+) + NADPH.
33704	3beta-hydroxy-5alpha-steroid dehydrogenase activity	F	Catalysis of the reaction: 3beta-hydroxy-5alpha-pregnane-20-one + NADP(+) = 5alpha-pregnane-3,20-dione + H(+) + NADPH.
33705	GDP-4-dehydro-6-deoxy-D-mannose reductase activity	F	Catalysis of the reaction: GDP-6-deoxy-D-mannose + NAD(P)+ = GDP-4-dehydro-6-deoxy-D-mannose + NAD(P)H + H+.
33707	3''-deamino-3''-oxonicotianamine reductase activity	F	Catalysis of the reaction: 2'-deoxymugineic acid + NAD(P)+ = 3''-deamino-3''-oxonicotianamine + NAD(P)H + H+.
33708	isocitrate-homoisocitrate dehydrogenase activity	F	Catalysis of the reactions: isocitrate + NAD+ = 2-oxoglutarate + CO2 + NADH, and (1R,2S)-1-hydroxybutane-1,2,4-tricarboxylate + NAD+ = 2-oxoadipate + CO2 + NADH + H+.
33709	D-arabinitol dehydrogenase, D-ribulose forming (NADP+) activity	F	Catalysis of the reaction: D-arabinitol + NADP+ = D-ribulose + NADPH + H+.
33711	4-phosphoerythronate dehydrogenase activity	F	Catalysis of the reaction: 4-phospho-D-erythronate + NAD(+) = (R)-3-hydroxy-2-oxo-4-phosphonooxybutanoate + H(+) + NADH.
33712	1,5-anhydro-D-fructose reductase (1,5-anhydro-D-mannitol-forming) activity	F	Catalysis of the reaction: 1,5-anhydro-D-mannitol + NADP(+) = 1,5-anhydro-D-fructose + H(+) + NADPH.
33713	choline:oxygen 1-oxidoreductase activity	F	Catalysis of the reaction: choline + O2 = betaine aldehyde + hydrogen peroxide.
33714	secondary-alcohol oxidase activity	F	Catalysis of the reaction: O(2) + secondary alcohol = H(2)O(2) + ketone.
33715	nucleoside oxidase activity	F	Catalysis of the reactions: inosine + O2 = 9-riburonosylhypoxanthine + 2 H2O; (1a) 2 inosine + O2 = 2 5'-dehydroinosine + 2 H2O, and (1b) 2 5'-dehydroinosine + O2 = 2 9-riburonosylhypoxanthine + 2 H2O.
33716	nucleoside oxidase (hydrogen peroxide-forming) activity	F	Catalysis of the reactions: adenosine + 2 O2 = 9-riburonosyladenine + 2 hydrogen peroxide; (1a) adenosine + O2 = 5'-dehydroadenosine + hydrogen peroxide, and (1b) 5'-dehydroadenosine + O2 = 9-riburonosyladenine + hydrogen peroxide.
33717	gluconate 2-dehydrogenase (acceptor) activity	F	Catalysis of the reaction: D-gluconate + acceptor = 2-dehydro-D-gluconate + reduced acceptor.
33718	pyranose dehydrogenase (acceptor) activity	F	Catalysis of the reactions: pyranose + acceptor = 2-dehydropyranose (or 3-dehydropyranose or 2,3-didehydropyranose) + reduced acceptor, and a pyranoside + acceptor = a 3-dehydropyranoside (or 3,4-didehydropyranoside) + reduced acceptor.
33719	2-oxo-acid reductase activity	F	Catalysis of the reaction: a (2R)-hydroxy-carboxylate + acceptor = a 2-oxo-carboxylate + reduced acceptor.
33720	(S)-mandelate dehydrogenase activity	F	Catalysis of the reaction: (S)-2-hydroxy-2-phenylacetate + acceptor = 2-oxo-2-phenylacetate + reduced acceptor.
33721	aldehyde dehydrogenase (NADP+) activity	F	Catalysis of the reaction: an aldehyde + NADP+ + H2O = an acid + NADPH + H+.
33722	malonate-semialdehyde dehydrogenase activity	F	Catalysis of the reaction: 3-oxopropanoate + NAD(P)+ + H2O = malonate + NAD(P)H + H+.
33723	fluoroacetaldehyde dehydrogenase activity	F	Catalysis of the reaction: fluoroacetaldehyde + NAD+ + H2O = fluoroacetate + NADH + 2 H+.
33726	aldehyde ferredoxin oxidoreductase activity	F	Catalysis of the reaction: an aldehyde + H2O + 2 oxidized ferredoxin = an acid + 2 H+ + 2 reduced ferredoxin.
33727	aldehyde dehydrogenase (FAD-independent) activity	F	Catalysis of the reaction: an aldehyde + H2O + acceptor = a carboxylate + reduced acceptor.
33728	divinyl chlorophyllide a 8-vinyl-reductase activity	F	Catalysis of the reaction: chlorophyllide a + NADP+ = divinyl chlorophyllide a + NADPH + H+.
33729	anthocyanidin reductase activity	F	Catalysis of the reaction: a flavan-3-ol + 2 NAD(P)+ = an anthocyanidin + 2 NAD(P)H + H+.
33730	arogenate dehydrogenase (NADP+) activity	F	Catalysis of the reaction: L-arogenate + NADP+ = L-tyrosine + NADPH + CO2.
33731	arogenate dehydrogenase [NAD(P)+] activity	F	Catalysis of the reaction: L-arogenate + NAD(P)+ = L-tyrosine + NAD(P)H + CO2.
33732	pyrroloquinoline-quinone synthase activity	F	Catalysis of the reaction: 6-(2-amino-2-carboxyethyl)-7,8-dioxo-1,2,3,4,7,8-hexahydroquinoline-2,4-dicarboxylate + 3 O(2) = 2 H(2)O + 2 H(2)O(2) + H(+) + pyrroloquinoline quinone.
33734	(R)-benzylsuccinyl-CoA dehydrogenase activity	F	Catalysis of the reaction: (R)-2-benzylsuccinyl-CoA + 2 electron-transferring flavoprotein = (E)-2-benzylidenesuccinyl-CoA + 2 reduced electron-transferring flavoprotein.
33735	aspartate dehydrogenase activity	F	Catalysis of the reaction: L-aspartate + H2O + NAD(P)+ = oxaloacetate + NH3 + NAD(P)H + H+.
33736	L-lysine 6-oxidase activity	F	Catalysis of the reaction: L-lysine + H(2)O + O(2) = allysine + H(2)O(2) + NH(4)(+).
33737	1-pyrroline dehydrogenase activity	F	Catalysis of the reaction: 1-pyrroline + NAD+ + 2 H2O = 4-aminobutanoate + NADH + 2 H+.
33738	methylenetetrahydrofolate reductase (ferredoxin) activity	F	Catalysis of the reaction: 5-methyltetrahydrofolate + oxidized ferredoxin = 5,10-methylenetetrahydrofolate + reduced ferredoxin.
33739	preQ1 synthase activity	F	Catalysis of the reaction: 7-aminomethyl-7-deazaguanine + 2 NADP(+) = 7-cyano-7-deazaguanine + 3 H(+) + 2 NADPH.
33740	hydroxylamine oxidoreductase activity	F	Catalysis of the reactions: hydroxylamine + NH3 = hydrazine + H2O, and hydrazine + acceptor = N2 + reduced acceptor.
33741	adenylyl-sulfate reductase (glutathione) activity	F	Catalysis of the reaction: AMP + glutathione disulfide + H(+) + sulfite = 5'-adenylyl sulfate + 2 glutathione.
33743	peptide-methionine (R)-S-oxide reductase activity	F	Catalysis of the reaction: peptide-L-methionine + H(2)O + thioredoxin disulfide = peptide-L-methionine (R)-S-oxide + thioredoxin. Can act on oxidized methionine in peptide linkage with specificity for the R enantiomer. Thioredoxin disulfide is the oxidized form of thioredoxin.
33744	L-methionine:thioredoxin-disulfide S-oxidoreductase activity	F	Catalysis of the reaction: L-methionine + thioredoxin disulfide + H2O = L-methionine (S)-S-oxide + thioredoxin.
33745	L-methionine-(R)-S-oxide reductase activity	F	Catalysis of the reaction: L-methionine + thioredoxin disulfide + H2O = L-methionine (R)-S-oxide + thioredoxin.
33746	histone demethylase activity (H3-R2 specific)	F	Catalysis of the removal of a methyl group from arginine at position 2 of the histone H3 protein.
33748	hydrogenase (acceptor) activity	F	Catalysis of the reaction: H2 + A = AH2.
33749	histone demethylase activity (H4-R3 specific)	F	Catalysis of the removal of a methyl group from arginine at position 3 of the histone H4 protein.
33750	ribosome localization	P	A process in which a ribosome is transported to, and/or maintained in, a specific location.
33751	linoleate diol synthase activity	F	Catalysis of the reaction: linoleate + O2 = (9Z,12Z)-(7S,8S)-dihydroxyoctadeca-9,12-dienoate.
33752	acetylacetone-cleaving enzyme activity	F	Catalysis of the reaction: pentane-2,4-dione + O2 = acetate + 2-oxopropanal.
33753	establishment of ribosome localization	P	The directed movement of the ribosome to a specific location.
33754	indoleamine 2,3-dioxygenase activity	F	Catalysis of the reaction: tryptophan + O2 = N-formylkynurenine. The product of the reaction depends on the substrate; D-tryptophan produces N-formyl-D-kynurenine, and L-tryptophan produces N-formyl-L-kynurenine.
33755	sulfur oxygenase/reductase activity	F	Catalysis of the reaction: 4 sulfur + 4 H2O + O2 = 2 hydrogen sulfide + 2 bisulfite + 2 H+.
33756	Oplophorus-luciferin 2-monooxygenase activity	F	Catalysis of the reaction: Oplophorus luciferin + O2 = oxidized Oplophorus luciferin + CO2 + hnu.
33757	glucoside 3-dehydrogenase activity	F	Catalysis of the reaction: sucrose + acceptor = 3-dehydro-alpha-D-glucosyl-beta-D-fructofuranoside + reduced acceptor.
33758	clavaminate synthase activity	F	Catalysis of the reactions: deoxyamidinoproclavaminate + 2-oxoglutarate + O2 = amidinoproclavaminate + succinate + CO2 + H2O; proclavaminate + 2-oxoglutarate + O2 = dihydroclavaminate + succinate + CO2 + 2 H2O; and dihydroclavaminate + 2-oxoglutarate + O2 = clavaminate + succinate + CO2 + 2 H2O.
33759	flavone synthase activity	F	Catalysis of the reaction: a flavanone + 2-oxoglutarate + O2 = a flavone + succinate + CO2 + H2O.
33760	2'-deoxymugineic-acid 2'-dioxygenase activity	F	Catalysis of the reaction: 2'-deoxymugineate + 2-oxoglutarate + O(2) = CO(2) + H(+) + mugineate + succinate.
33761	mugineic-acid 3-dioxygenase activity	F	Catalysis of the reactions: mugineic acid + 2-oxoglutarate + O2 = 3-epihydroxymugineic acid + succinate + CO2.
33762	response to glucagon	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucagon stimulus.
33763	proline 3-hydroxylase activity	F	Catalysis of the reaction: L-proline + 2-oxoglutarate + O2 = cis-3-hydroxy-L-proline + succinate + CO2.
33764	steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	F	Catalysis of an oxidation-reduction (redox) reaction in which a CH-OH group acts as a hydrogen or electron donor and reduces NAD+ or NADP, and in which one substrate is a sterol derivative.
33765	steroid dehydrogenase activity, acting on the CH-CH group of donors	F	Catalysis of an oxidation-reduction (redox) reaction in which a CH-CH group acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor, and in which one substrate is a sterol derivative.
33766	2-hydroxyquinoline 8-monooxygenase activity	F	Catalysis of the reaction: H(+) + NADH + O(2) + quinolin-2-ol = H(2)O + NAD(+) + quinoline-2,8-diol.
33767	4-hydroxyacetophenone monooxygenase activity	F	Catalysis of the reaction: 4'-hydroxyacetophenone + H(+) + NADPH + O(2) = 4-hydroxyphenyl acetate + H(2)O + NADP(+).
33768	SUMO-targeted ubiquitin ligase complex	C	A nuclear ubiquitin ligase complex that specifically targets SUMOylated proteins; the complex is formed of homodimers or heterodimers of RNF4 family ubiquitin ligases and is conserved in eukaryotes.
33769	glyceollin synthase activity	F	Catalysis of the reactions: 2-dimethylallyl-(6aS,11aS)-3,6a,9-trihydroxypterocarpan + NADPH + H+ + O2 = glyceollin + NADP+ + 2 H2O, and 4-dimethylallyl-(6aS,11aS)-3,6a,9-trihydroxypterocarpan + NADPH + H+ + O2 = glyceollin + NADP+ + 2 H2O.
33770	2-hydroxyisoflavanone synthase activity	F	Catalysis of the reaction: apigenin + 2 NADPH + 2 H+ + O2 = 2-hydroxy-2,3-dihydrogenistein + 2 NADP+ + H2O.
33771	licodione synthase activity	F	Catalysis of the reaction: H(+) + liquiritigenin + NADPH + O(2) = H(2)O + licodione + NADP(+).
33772	flavonoid 3',5'-hydroxylase activity	F	Catalysis of the reactions: a flavanone + NADPH + H+ + O2 = a 3'-hydroxyflavanone + NADP+ + H2O, and a 3'-hydroxyflavanone + NADPH + H+ + O2 = a 3',5'-dihydroxyflavanone + NADP+ + H2O.
33773	isoflavone 2'-hydroxylase activity	F	Catalysis of the reaction: an isoflavone + NADPH + H+ + O2 = a 2'-hydroxyisoflavone + NADP+ + H2O.
33774	basal labyrinth	C	A region in the lower half of some cells formed from extensive infoldings of the basal plasma membrane; includes cytoplasm adjacent to the infolded membrane.
33775	deoxysarpagine hydroxylase activity	F	Catalysis of the reaction: 10-deoxysarpagine + H(+) + NADPH + O(2) = H(2)O + NADP(+) + sarpagine.
33776	phenylacetone monooxygenase activity	F	Catalysis of the reaction: H(+) + NADPH + O(2) + phenylacetone = benzyl acetate + H(2)O + NADP(+).
33777	lithocholate 6beta-hydroxylase activity	F	Catalysis of the reaction: H(+) + lithocholate + NADPH + O(2) = 6-beta-hydroxylithocholate + H(2)O + NADP(+).
33778	7alpha-hydroxycholest-4-en-3-one 12alpha-hydroxylase activity	F	Catalysis of the reaction: 7alpha-hydroxycholest-4-en-3-one + H(+) + NADPH + O(2) = 7alpha,12alpha-dihydroxycholest-4-en-3-one + H(2)O + NADP(+).
33779	5beta-cholestane-3alpha,7alpha-diol 12alpha-hydroxylase activity	F	Catalysis of the reaction: 5beta-cholestane-3alpha,7alpha-diol + H(+) + NADPH + O(2) = 5beta-cholestane-3alpha,7alpha,12alpha-triol + H(2)O + NADP(+).
33780	taurochenodeoxycholate 6alpha-hydroxylase activity	F	Catalysis of the reactions: taurochenodeoxycholate + NADPH + H+ + O2 = taurohyocholate + NADP+ + H2O, and lithocholate + NADPH + H+ + O2 = hyodeoxycholate + NADP+ + H2O.
33781	cholesterol 24-hydroxylase activity	F	Catalysis of the reaction: cholesterol + H(+) + NADPH + O(2) = (24S)-24-hydroxycholesterol + H(2)O + NADP(+).
33782	24-hydroxycholesterol 7alpha-hydroxylase activity	F	Catalysis of the reaction: (24R)-cholest-5-ene-3beta,24-diol + H(+) + NADPH + O(2) = (24R)-7alpha,24-dihydroxycholesterol + H(2)O + NADP(+).
33783	25-hydroxycholesterol 7alpha-hydroxylase activity	F	Catalysis of the reactions: cholest-5-ene-3beta,25-diol + NADPH + H+ + O2 = cholest-5-ene-3beta,7alpha,25-triol + NADP+ + H2O, and cholest-5-ene-3beta,27-diol + NADPH + H+ + O2 = cholest-5-ene-3beta,7alpha,27-triol + NADP+ + H2O.
33784	senecionine N-oxygenase activity	F	Catalysis of the reaction: H(+) + NADPH + O(2) + senecionine = H(2)O + NADP(+) + senecionine N-oxide.
33785	heptose 7-phosphate kinase activity	F	Catalysis of the reaction: D-alpha,beta-D-heptose-7-phosphate + ATP = D-beta-D-heptose-1,7-bisphosphate + ADP.
33786	heptose-1-phosphate adenylyltransferase activity	F	Catalysis of the reaction: D-beta-D-heptose-1-phosphate + ATP = ADP-D-glycero-D-manno-heptose.
33787	cyanocobalamin reductase (cyanide-eliminating) activity	F	Catalysis of the reaction: cob(I)alamin + hydrogen cyanide + NADP(+) = cyanocob(III)alamin + H(+) + NADPH.
33788	leucoanthocyanidin reductase activity	F	Catalysis of the reaction: (2R,3S)-catechin + NADP+ + H2O = 2,3-trans-3,4-cis-leucocyanidin + NADPH + H+.
33789	phenylacetyl-CoA dehydrogenase activity	F	Catalysis of the reaction: 2 1,4-benzoquinone + H(2)O + phenylacetyl-CoA = 2 hydroquinone + phenylglyoxylyl-CoA.
33790	hydroxymethylfurfural reductase activity	F	Catalysis of the reaction: 5-hydroxymethylfurfural + NAD(P)H + H+ = 2,5-bis-hydroxymethylfuran + NAD(P)+.
33791	3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl-CoA 24-hydroxylase activity	F	Catalysis of the reaction: (25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oyl-CoA + H2O + acceptor = (24R,25R)-3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestan-26-oyl-CoA + reduced acceptor.
33792	bile-acid 7alpha-dehydroxylase activity	F	Catalysis of the reactions: deoxycholate + FAD + H2O = cholate + FADH2, and lithocholate + FAD + H2O = chenodeoxycholate + FADH2.
33793	aureusidin synthase activity	F	Catalysis of the reactions: 2',4,4',6'-tetrahydroxychalcone + O2 = aureusidin + H2O, and 2',3,4,4',6'-pentahydroxychalcone + 1/2 O2 = aureusidin + H2O.
33794	sarcosine reductase activity	F	Catalysis of the reaction: acetyl phosphate + methylamine + thioredoxin disulfide = N-methylglycine + phosphate + thioredoxin.
33795	betaine reductase activity	F	Catalysis of the reaction: acetyl phosphate + trimethylamine + thioredoxin disulfide = N,N,N-trimethylglycine + phosphate + thioredoxin.
33796	sulfur reductase activity	F	Catalysis of the reduction of elemental sulfur or polysulfide to hydrogen sulfide.
33797	selenate reductase activity	F	Catalysis of the reaction: 2 e(-) + 2 H(+) + selenate = H(2)O + selenite.
33798	thyroxine 5-deiodinase activity	F	Catalysis of the reaction: 3,3',5'-triiodo-L-thyronine + iodide + A + H+ = L-thyroxine + AH2.
33799	myricetin 3'-O-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + myricetin = S-adenosyl-L-homocysteine + laricitrin.
33800	isoflavone 7-O-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + a 7-hydroxyisoflavone = S-adenosyl-L-homocysteine + a 7-methoxyisoflavone.
33801	vitexin 2''-O-rhamnoside 7-O-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + vitexin 2''-O-beta-L-rhamnoside = S-adenosyl-L-homocysteine + 7-O-methylvitexin 2''-O-beta-L-rhamnoside.
33802	isoliquiritigenin 2'-O-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + isoliquiritigenin = 2'-O-methylisoliquiritigenin + S-adenosyl-L-homocysteine + H(+).
33803	kaempferol 4'-O-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + kaempferol = S-adenosyl-L-homocysteine + H(+) + kaempferide.
33806	fluorothreonine transaldolase activity	F	Catalysis of the reaction: L-threonine + fluoroacetaldehyde = acetaldehyde + 4-fluoro-L-threonine.
33807	icosanoyl-CoA synthase activity	F	Catalysis of the reaction: stearoyl-CoA + malonyl-CoA + 2 NAD(P)H + 2 H+ = icosanoyl-CoA + CO2 + 2 NAD(P)+.
33808	6'-deoxychalcone synthase activity	F	Catalysis of the reaction: 3 malonyl-CoA + 4-coumaroyl-CoA + NADPH + H+ = 4 CoA + isoliquiritigenin + 3 CO2 + NADP+ + H2O.
33809	anthocyanin 6''-O-malonyltransferase activity	F	Catalysis of the reaction: malonyl-CoA + an anthocyanidin 3-O-beta-D-glucoside = CoA + an anthocyanidin 3-O-(6-O-malonyl-beta-D-glucoside).
33810	anthocyanin 5-O-glucoside 6'''-O-malonyltransferase activity	F	Catalysis of the reaction: malonyl-CoA + pelargonidin 3-O-(6-caffeoyl-beta-D-glucoside) 5-O-beta-D-glucoside = CoA + 4'''-demalonylsalvianin.
33811	flavonol-3-O-triglucoside O-coumaroyltransferase activity	F	Catalysis of the reaction: 4-coumaroyl-CoA + a flavonol 3-O-[beta-D-glucosyl-(1->2)-beta-D-glucosyl-(1->2)-beta-D-glucoside] = CoA + a flavonol 3-O-[6-(4-coumaroyl)-beta-D-glucosyl-(1->2)-beta-D-glucosyl-(1->2)-beta-D-glucoside].
33812	3-oxoadipyl-CoA thiolase activity	F	Catalysis of the reaction: succinyl-CoA + acetyl-CoA = CoA + 3-oxoadipyl-CoA.
33813	deacetylcephalosporin-C acetyltransferase activity	F	Catalysis of the reaction: acetyl-CoA + deacetylcephalosporin C = cephalosporin C + CoA.
33814	propanoyl-CoA C-acyltransferase activity	F	Catalysis of the reaction: 3alpha,7alpha,12alpha-trihydroxy-5beta-cholanoyl-CoA + propanoyl-CoA = CoA + 3alpha,7alpha,12alpha-trihydroxy-24-oxo-5beta-cholestanoyl-CoA.
33815	biphenyl synthase activity	F	Catalysis of the reaction: 3 malonyl-CoA + benzoyl-CoA = 4 CoA + 3,5-dihydroxybiphenyl + 4 CO2.
33816	diaminobutyrate acetyltransferase activity	F	Catalysis of the reaction: L-2,4-diaminobutyrate + acetyl-CoA = N(4)-acetyl-L-2,4-diaminobutyrate + CoA + H(+).
33817	beta-ketoacyl-acyl-carrier-protein synthase II activity	F	Catalysis of the reaction: (Z)-hexadec-11-enoyl-[acyl-carrier protein] + malonyl-[acyl-carrier protein] = (Z)-3-oxooctadec-13-enoyl-[acyl-carrier protein] + CO2 + [acyl-carrier protein].
33818	beta-ketoacyl-acyl-carrier-protein synthase III activity	F	Catalysis of the reaction: acetyl-CoA + malonyl-[acyl-carrier protein] = acetoacyl-[acyl-carrier protein] + CoA + CO2.
33819	lipoyl(octanoyl) transferase activity	F	Catalysis of the reaction: octanoyl-[acyl-carrier protein] + protein = protein N6-(octanoyl)lysine + acyl-carrier protein.
33820	DNA alpha-glucosyltransferase activity	F	Catalysis of the transfer of an alpha-D-glucosyl residue from UDP-glucose to a hydroxymethylcytosine residue in DNA.
33821	DNA beta-glucosyltransferase activity	F	Catalysis of the transfer of a beta-D-glucosyl residue from UDP-glucose to a hydroxymethylcytosine residue in DNA.
33822	glucosyl-DNA beta-glucosyltransferase activity	F	Catalysis of the transfer of a beta-D-glucosyl residue from UDP-glucose to a glucosylhydroxymethylcytosine residue in DNA.
33823	procollagen glucosyltransferase activity	F	Catalysis of the reaction: UDP-glucose + 5-(D-galactosyloxy)-L-lysine-procollagen = UDP + 1,2-D-glucosyl-5-D-(galactosyloxy)-L-lysine-procollagen.
33824	alternansucrase activity	F	Catalysis of the transfer of an alpha-D-glucosyl residue from sucrose to alternately the 6-position and the 3-position of the non-reducing terminal residue of an alpha-D-glucan, thus producing a glucan having alternating alpha-1,6- and alpha-1,3-linkages.
33825	oligosaccharide 4-alpha-D-glucosyltransferase activity	F	Catalysis of the transfer of the non-reducing terminal alpha-D-glucose residue from a 1,4-alpha-D-glucan to the 4-position of an alpha-D-glucan, thus bringing about the hydrolysis of oligosaccharides.
33826	xyloglucan 4-glucosyltransferase activity	F	Catalysis of the transfer of a beta-D-glucosyl residue from UDP-glucose on to a glucose residue in xyloglucan, forming a beta-1,4-D-glucosyl-D-glucose linkage.
33827	high-mannose-oligosaccharide beta-1,4-N-acetylglucosaminyltransferase activity	F	Catalysis of the transfer of an N-acetyl-D-glucosamine residue from UDP-N-acetyl-D-glucosamine to the 4-position of a mannose linked alpha-1,6 to the core mannose of high-mannose oligosaccharides produced by Dictyostelium discoideum.
33828	glucosylglycerol-phosphate synthase activity	F	Catalysis of the reaction: sn-glycerol 3-phosphate + ADP-glucose = 2-O-(beta-D-glucosyl)-sn-glycerol 3-phosphate + ADP + H(+).
33829	O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity	F	Catalysis of the transfer of a beta-D-GlcNAc residue from UDP-D-GlcNAc to the fucose residue of a fucosylated protein acceptor.
33830	Skp1-protein-hydroxyproline N-acetylglucosaminyltransferase activity	F	Catalysis of the reaction: UDP-N-acetylglucosamine + Skp1-protein-hydroxyproline = UDP + Skp1-protein-O-(N-acetyl-D-glucosaminyl)hydroxyproline.
33831	kojibiose phosphorylase activity	F	Catalysis of the reaction: kojibiose + phosphate = beta-D-glucose 1-phosphate + D-glucose.
33832	alpha,alpha-trehalose phosphorylase (configuration-retaining) activity	F	Catalysis of the reaction: alpha,alpha-trehalose + phosphate = alpha-D-glucose + alpha-D-glucose 1-phosphate.
33833	hydroxymethylfurfural reductase (NADH) activity	F	Catalysis of the reaction: 5-hydroxymethylfurfural + NADH + H+ = 2,5-bis-hydroxymethylfuran + NAD+.
33834	kaempferol 3-O-galactosyltransferase activity	F	Catalysis of the reaction: UDP-galactose + kaempferol = UDP + kaempferol 3-O-beta-D-galactoside.
33835	flavanone 7-O-glucoside 2''-O-beta-L-rhamnosyltransferase activity	F	Catalysis of the reaction: UDP-L-rhamnose + a flavanone 7-O-glucoside = UDP + a flavanone 7-O-[beta-L-rhamnosyl-(1->2)-beta-D-glucoside].
33836	flavonol 7-O-beta-glucosyltransferase activity	F	Catalysis of the reaction: UDP-glucose + a flavonol = UDP + a flavonol 7-O-beta-D-glucoside.
33837	anthocyanin 3'-O-beta-glucosyltransferase activity	F	Catalysis of the reaction: UDP-glucose + an anthocyanin = UDP + an anthocyanin 3'-O-beta-D-glucoside.
33838	flavonol-3-O-glucoside glucosyltransferase activity	F	Catalysis of the reaction: UDP-glucose + a flavonol 3-O-beta-D-glucoside = UDP + a flavonol 3-O-beta-D-glucosyl-(1->2)-beta-D-glucoside.
33839	flavonol-3-O-glycoside glucosyltransferase activity	F	Catalysis of the reaction: UDP-glucose + a flavonol 3-O-beta-D-glucosyl-(1->2)-beta-D-glucoside = UDP + a flavonol 3-O-beta-D-glucosyl-(1->2)-beta-D-glucosyl-(1->2)-beta-D-glucoside.
33840	NDP-glucose-starch glucosyltransferase activity	F	Catalysis of the reaction: NDP-glucose + (1,4-alpha-D-glucosyl)n = NDP + (1,4-alpha-D-glucosyl)n+1.
33841	6G-fructosyltransferase activity	F	Catalysis of the reaction: [1-beta-D-fructofuranosyl-(2->1)-]m+1 alpha-D-glucopyranoside + [1-beta-D-fructofuranosyl-(2->1)-]n+1 alpha-D-glucopyranoside = [1-beta-D-fructofuranosyl-(2->1)-]m alpha-D-glucopyranoside + [1-beta-D-fructofuranosyl-(2->1)-]n+1 beta-D-fructofuranosyl-(2->6)-alpha-D-glucopyranoside (m > 0; n >= 0).
33842	N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase activity	F	Catalysis of the reaction: UDP-N-acetyl-D-galactosamine + N-acetyl-beta-D-glucosaminyl group = UDP + N-acetyl-beta-D-galactosaminyl-(1->4)-N-acetyl-beta-D-glucosaminyl group.
33843	xyloglucan 6-xylosyltransferase activity	F	Catalysis of the transfer of an alpha-D-xylosyl residue from UDP-D-xylose to a glucose residue in xyloglucan, forming an alpha-1,6-D-xylosyl-D-glucose linkage.
33844	galactose-6-sulfurylase activity	F	Catalysis of the elimination of sulfate from the D-galactose 6-sulfate residues of porphyran, producing 3,6-anhydrogalactose residues.
33845	hydroxymethylfurfural reductase (NADPH) activity	F	Catalysis of the reaction: 5-hydroxymethylfurfural + NADPH + H+ = 2,5-bis-hydroxymethylfuran + NADP+.
33846	adenosyl-fluoride synthase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + fluoride = 5'-deoxy-5'-fluoroadenosine + L-methionine.
33847	O-phosphoserine sulfhydrylase activity	F	Catalysis of the reaction: O-phospho-L-serine + hydrogen sulfide = L-cysteine + phosphate.
33848	N2-(2-carboxyethyl)arginine synthase activity	F	Catalysis of the reaction: D-glyceraldehyde 3-phosphate + L-arginine = N(2)-(2-carboxyethyl)-L-arginine + H(+) + phosphate.
33849	chrysanthemyl diphosphate synthase activity	F	Catalysis of the reaction: 2 dimethylallyl diphosphate = (R,R)-chrysanthemyl diphosphate + diphosphate.
33850	Z-farnesyl diphosphate synthase activity	F	Catalysis of the reaction: geranyl diphosphate + isopentenyl diphosphate = 2-cis,6-trans-farnesyl diphosphate + diphosphate.
33851	lavandulyl diphosphate synthase activity	F	Catalysis of the reaction: 2 dimethylallyl diphosphate = diphosphate + lavandulyl diphosphate.
33852	thyroid-hormone transaminase activity	F	Catalysis of the reaction: 2-oxoglutarate + 3,5,3'-triiodo-L-thyronine = 3,5,3'-triiodothyropyruvate + L-glutamate.
33853	aspartate-prephenate aminotransferase activity	F	Catalysis of the reaction: L-arogenate + oxaloacetate = prephenate + L-aspartate.
33854	glutamate-prephenate aminotransferase activity	F	Catalysis of the reaction: 2-oxoglutarate + L-arogenate = L-glutamate + prephenate.
33855	nicotianamine aminotransferase activity	F	Catalysis of the reaction: 2-oxoglutarate + nicotianamine = 3''-deamino-3''-oxonicotianamine + L-glutamate.
33856	pyridoxine 5'-phosphate synthase activity	F	Catalysis of the reaction: 1-deoxy-D-xylulose 5-phosphate + 3-amino-2-oxopropyl phosphate = 2 H(2)O + H(+) + phosphate + pyridoxine 5'-phosphate.
33857	diphosphoinositol-pentakisphosphate kinase activity	F	Catalysis of the reaction: ATP + 1D-myo-inositol 5-diphosphate pentakisphosphate = ADP + 1D-myo-inositol bisdiphosphate tetrakisphosphate.
33858	N-acetylgalactosamine kinase activity	F	Catalysis of the reaction: ATP + N-acetyl-D-galactosamine = ADP + N-acetyl-alpha-D-galactosamine 1-phosphate.
33859	furaldehyde metabolic process	P	The chemical reactions and pathways involving furaldehyde, a furan ring-containing aldehyde compound which can be formed from the thermal decomposition of biomass.
33860	regulation of NAD(P)H oxidase activity	P	Any process that modulates the activity of the enzyme NAD(P)H oxidase.
33861	negative regulation of NAD(P)H oxidase activity	P	Any process that stops or reduces the activity of the enzyme NAD(P)H oxidase.
33862	UMP kinase activity	F	Catalysis of the reaction: ATP + UMP = ADP + UDP.
33863	ribose 1,5-bisphosphate phosphokinase activity	F	Catalysis of the reaction: D-ribose 1,5-diphosphate + ATP = 5-phospho-alpha-D-ribose 1-diphosphate + ADP + H(+).
33864	positive regulation of NAD(P)H oxidase activity	P	Any process that activates or increases the activity of the enzyme NAD(P)H oxidase.
33865	nucleoside bisphosphate metabolic process	P	The chemical reactions and pathways involving a nucleoside bisphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar.
33866	nucleoside bisphosphate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of a nucleoside bisphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar.
33867	Fas-activated serine/threonine kinase activity	F	Catalysis of the reaction: ATP + Fas-activated serine/threonine protein = ADP + Fas-activated serine/threonine phosphoprotein.
33868	Goodpasture-antigen-binding protein kinase activity	F	Catalysis of the reaction: ATP + Goodpasture antigen-binding protein = ADP + Goodpasture antigen-binding phosphoprotein.
33869	nucleoside bisphosphate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of a nucleoside bisphosphate, a compound consisting of a nucleobase linked to a deoxyribose or ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar.
33870	thiol sulfotransferase activity	F	Catalysis of the reaction: 3'-phosphoadenylyl sulfate + a thiol = adenosine 3',5'-bisphosphate + an S-alkyl thiosulfate.
33871	[heparan sulfate]-glucosamine 3-sulfotransferase 2 activity	F	Catalysis of the reaction: 3'-phosphoadenylyl sulfate + [heparan sulfate]-glucosamine = adenosine 3',5'-bisphosphate + [heparan sulfate]-glucosamine 3-sulfate; modifies selected glucosamine residues preceded by GlcA2S.
33872	[heparan sulfate]-glucosamine 3-sulfotransferase 3 activity	F	Catalysis of the reaction: 3'-phosphoadenylyl sulfate + [heparan sulfate]-glucosamine = adenosine 3',5'-bisphosphate + [heparan sulfate]-glucosamine 3-sulfate.
33873	petromyzonol sulfotransferase activity	F	Catalysis of the reaction: 3'-phospho-5'-adenylyl sulfate + 5alpha-cholane-3alpha,7alpha,12alpha,24-tetrol = 3alpha,7alpha,12alpha-trihydroxy-5alpha-cholan-24-yl sulfate + adenosine 3',5'-diphosphate + H(+).
33874	scymnol sulfotransferase activity	F	Catalysis of the reaction: 3'-phospho-5'-adenylyl sulfate + 5beta-scymnol = 5beta-scymnol sulfate + adenosine 3',5'-diphosphate + H(+).
33875	ribonucleoside bisphosphate metabolic process	P	The chemical reactions and pathways involving a ribonucleoside bisphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar.
33876	glycochenodeoxycholate sulfotransferase activity	F	Catalysis of the reaction: 3'-phospho-5'-adenylyl sulfate + glycochenodeoxycholate = adenosine 3',5'-diphosphate + glycochenodeoxycholate 7-sulfate + H(+).
33877	succinyl-CoA:(R)-benzylsuccinate CoA-transferase activity	F	Catalysis of the reaction: (R)-2-benzylsuccinate + succinyl-CoA = (R)-2-benzylsuccinyl-CoA + succinate.
33878	hormone-sensitive lipase activity	F	Catalysis of the reactions: diacylglycerol + H2O = monoacylglycerol + a carboxylate; triacylglycerol + H2O = diacylglycerol + a carboxylate; and monoacylglycerol + H2O = glycerol + a carboxylate.
33879	acetylajmaline esterase activity	F	Catalysis of the reactions: 17-O-acetylajmaline + H2O = ajmaline + acetate, and 17-O-acetylnorajmaline + H2O = norajmaline + acetate.
33880	phenylacetyl-CoA hydrolase activity	F	Catalysis of the reaction: H(2)O + phenylglyoxylyl-CoA = CoA + H(+) + phenylglyoxylate.
33881	bile-acid-CoA hydrolase activity	F	Catalysis of the reaction: deoxycholoyl-CoA + H(2)O = CoA + deoxycholate + H(+).
33882	choloyl-CoA hydrolase activity	F	Catalysis of the reaction: choloyl-CoA + H2O = cholate + CoA.
33883	pyridoxal phosphatase activity	F	Catalysis of the reaction: pyridoxal 5'-phosphate + H2O = pyridoxal + phosphate.
33885	10-hydroxy-9-(phosphonooxy)octadecanoate phosphatase activity	F	Catalysis of the reaction: (9S,10S)-10-hydroxy-9-(phosphonooxy)octadecanoate + H(2)O = (9S,10S)-9,10-dihydroxyoctadecanoate + phosphate.
33886	cellulose-polysulfatase activity	F	Catalysis of the hydrolysis of the 2- and 3-sulfate groups of the polysulfates of cellulose and charonin.
33887	chondro-4-sulfatase activity	F	Catalysis of the reaction: 4-deoxy-beta-D-gluc-4-enuronosyl-(1->3)-N-acetyl-D-galactosamine 4-sulfate + H(2)O = 4-deoxy-beta-D-gluc-4-enuronosyl-(1->3)-N-acetyl-D-galactosamine + H(+) + sulfate.
33888	chondro-6-sulfatase activity	F	Catalysis of the reaction: 4-deoxy-beta-D-gluc-4-enuronosyl-(1->3)-N-acetyl-D-galactosamine 6-sulfate + H(2)O = 4-deoxy-beta-D-gluc-4-enuronosyl-(1->3)-N-acetyl-D-galactosamine + H(+) + sulfate.
33889	N-sulfoglucosamine-3-sulfatase activity	F	Catalysis of the hydrolysis of the 3-sulfate groups of the N-sulfo-D-glucosamine 3-O-sulfate units of heparin.
33890	ribonuclease D activity	F	Catalysis of the exonucleolytic cleavage that removes extra residues from the 3'-terminus of tRNA to produce 5'-mononucleotides.
33891	CC-preferring endodeoxyribonuclease activity	F	Catalysis of the endonucleolytic cleavage to give 5'-phosphooligonucleotide end-products, with a preference for cleavage within the sequence CC.
33892	deoxyribonuclease (pyrimidine dimer) activity	F	Catalysis of the endonucleolytic cleavage near pyrimidine dimers to products with 5'-phosphate.
33893	ribonuclease IV activity	F	Catalysis of the endonucleolytic cleavage of poly(A) to fragments terminated by 3'-hydroxy and 5'-phosphate groups.
33894	ribonuclease P4 activity	F	Catalysis of the endonucleolytic cleavage of RNA, removing 3'-extranucleotides from tRNA precursor.
33895	ribonuclease [poly-(U)-specific] activity	F	Catalysis of the endonucleolytic cleavage of poly(U) to fragments terminated by 3'-hydroxy and 5'-phosphate groups.
33896	ribonuclease IX activity	F	Catalysis of the endonucleolytic cleavage of poly(U) or poly(C) to fragments terminated by 3'-hydroxy and 5'-phosphate groups.
33897	ribonuclease T2 activity	F	Catalysis of the two-stage endonucleolytic cleavage to nucleoside 3'-phosphates and 3'-phosphooligonucleotides with 2',3'-cyclic phosphate intermediates.
33898	Bacillus subtilis ribonuclease activity	F	Catalysis of the endonucleolytic cleavage to 2',3'-cyclic nucleotides.
33899	ribonuclease U2 activity	F	Catalysis of the two-stage endonucleolytic cleavage to nucleoside 3'-phosphates and 3'-phosphooligonucleotides ending in Ap or Gp with 2',3'-cyclic phosphate intermediates.
33900	ribonuclease F activity	F	Catalysis of the endonucleolytic cleavage of RNA precursor into two, leaving 5'-hydroxy and 3'-phosphate groups.
33901	ribonuclease V activity	F	Catalysis of the hydrolysis of poly(A), forming oligoribonucleotides and ultimately 3'-AMP.
33902	rRNA endonuclease activity	F	Catalysis of the hydrolysis of the phosphodiester linkage between guanosine and adenosine residues at one specific position in 28S rRNA from rat ribosomes.
33904	dextranase activity	F	Catalysis of the endohydrolysis of 1,6-alpha-D-glucosidic linkages in dextran.
33905	xylan endo-1,3-beta-xylosidase activity	F	Catalysis of the random hydrolysis of (1->3)-beta-D-glycosidic linkages in (1->3)-beta-D-xylans.
33906	hyaluronoglucuronidase activity	F	Catalysis of the random hydrolysis of 1,3-linkages between beta-D-glucuronate and N-acetyl-D-glucosamine residues in hyaluronate.
33907	beta-D-fucosidase activity	F	Catalysis of the hydrolysis of terminal non-reducing beta-D-fucose residues in beta-D-fucosides.
33908	beta-L-rhamnosidase activity	F	Catalysis of the hydrolysis of terminal, non-reducing beta-L-rhamnose residues in beta-L-rhamnosides.
33909	fucoidanase activity	F	Catalysis of the endohydrolysis of 1,2-alpha-L-fucoside linkages in fucoidan without release of sulfate.
33910	glucan 1,4-alpha-maltotetraohydrolase activity	F	Catalysis of the hydrolysis of (1->4)-alpha-D-glucosidic linkages in amylaceous polysaccharides, to remove successive maltotetraose residues from the non-reducing chain ends.
33911	mycodextranase activity	F	Catalysis of the endohydrolysis of 1,4-alpha-D-glucosidic linkages in alpha-D-glucans containing both 1,3- and 1,4-bonds.
33912	2,6-beta-fructan 6-levanbiohydrolase activity	F	Catalysis of the hydrolysis of (2->6)-beta-D-fructofuranan, to remove successive disaccharide residues as levanbiose, i.e. 6-(beta-D-fructofuranosyl)-D-fructose, from the end of the chain.
33913	glucan endo-1,2-beta-glucosidase activity	F	Catalysis of the random hydrolysis of (1->2)-glucosidic linkages in (1->2)-beta-D-glucans.
33914	xylan 1,3-beta-xylosidase activity	F	Catalysis of the hydrolysis of successive xylose residues from the non-reducing termini of (1->3)-beta-D-xylans.
33915	mannan 1,2-(1,3)-alpha-mannosidase activity	F	Catalysis of the hydrolysis of (1->2) and (1->3) linkages in mannan, releasing mannose.
33916	beta-agarase activity	F	Catalysis of the hydrolysis of (1->4)-beta-D-galactosidic linkages in agarose, giving the tetramer as the predominant product.
33917	exo-poly-alpha-galacturonosidase activity	F	Catalysis of the hydrolysis of pectic acid from the non-reducing end, releasing digalacturonate.
33918	kappa-carrageenase activity	F	Catalysis of the endohydrolysis of 1,4-beta-D-linkages between D-galactose 4-sulfate and 3,6-anhydro-D-galactose in kappa-carrageenans.
33919	glucan 1,3-alpha-glucosidase activity	F	Catalysis of the hydrolysis of terminal (1->3)-alpha-D-glucosidic links in 1,3-alpha-D-glucans.
33920	6-phospho-beta-galactosidase activity	F	Catalysis of the reaction: a 6-phospho-beta-D-galactoside + H2O = 6-phospho-D-galactose + an alcohol.
33921	capsular-polysaccharide endo-1,3-alpha-galactosidase activity	F	Catalysis of the random hydrolysis of (1->3)-alpha-D-galactosidic linkages in Aerobacter aerogenes capsular polysaccharide.
33922	peptidoglycan beta-N-acetylmuramidase activity	F	Catalysis of the hydrolysis of terminal, non-reducing N-acetylmuramic residues.
33923	glucan 1,6-alpha-isomaltosidase activity	F	Catalysis of the hydrolysis of (1->6)-alpha-D-glucosidic linkages in polysaccharides, to remove successive isomaltose units from the non-reducing ends of the chains.
33924	dextran 1,6-alpha-isomaltotriosidase activity	F	Catalysis of the hydrolysis of (1->6)-alpha-D-glucosidic linkages in dextrans, to remove successive isomaltotriose units from the non-reducing ends of the chains.
33925	mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase activity	F	Catalysis of the endohydrolysis of the N,N'-diacetylchitobiosyl unit in high-mannose glycopeptides and glycoproteins containing the -[Man(GlcNAc)2]Asn-structure. One N-acetyl-D-glucosamine residue remains attached to the protein; the rest of the oligosaccharide is released intact.
33926	glycopeptide alpha-N-acetylgalactosaminidase activity	F	Catalysis of the reaction: D-galactosyl-3-(N-acetyl-alpha-D-galactosaminyl)-L-serine + H2O = D-galactosyl-3-N-acetyl-alpha-D-galactosamine + L-serine.
33927	glucan 1,4-alpha-maltohexaosidase activity	F	Catalysis of the hydrolysis of (1->4)-alpha-D-glucosidic linkages in amylaceous polysaccharides, to remove successive maltohexaose residues from the non-reducing chain ends.
33928	mannan 1,4-mannobiosidase activity	F	Catalysis of the hydrolysis of (1->4)-beta-D-mannosidic linkages in (1->4)-beta-D-mannans, to remove successive mannobiose residues from the non-reducing chain ends.
33929	blood-group-substance endo-1,4-beta-galactosidase activity	F	Catalysis of the endohydrolysis of (1->4)-beta-D-galactosidic linkages in blood group A and B substances.
33930	keratan-sulfate endo-1,4-beta-galactosidase activity	F	Catalysis of the endohydrolysis of (1->4)-beta-D-galactosidic linkages in keratan sulfate.
33931	endogalactosaminidase activity	F	Catalysis of the endohydrolysis of (1->4)-alpha-D-galactosaminidic linkages in poly(D-galactosamine).
33932	1,3-alpha-L-fucosidase activity	F	Catalysis of the hydrolysis of (1->3) linkages between alpha-L-fucose and N-acetylglucosamine residues in glycoproteins.
33933	branched-dextran exo-1,2-alpha-glucosidase activity	F	Catalysis of the hydrolysis of (1->2)-alpha-D-glucosidic linkages at the branch points of dextrans and related polysaccharides, producing free D-glucose.
33934	glucan 1,4-alpha-maltotriohydrolase activity	F	Catalysis of the hydrolysis of (1->4)-alpha-D-glucosidic linkages in amylaceous polysaccharides, to remove successive maltotriose residues from the non-reducing chain ends.
33935	oligoxyloglucan beta-glycosidase activity	F	Catalysis of the hydrolysis of (1->4)-beta-D-glucosidic links in oligoxyloglucans so as to remove successive isoprimeverose (i.e. alpha-xylo-1,6-beta-D-glucosyl-) residues from the non-reducing chain ends.
33936	polymannuronate hydrolase activity	F	Catalysis of the endohydrolysis of the D-mannuronide linkages of polymannuronate.
33937	3-deoxy-2-octulosonidase activity	F	Catalysis of the endohydrolysis of the beta-ketopyranosidic linkages of 3-deoxy-D-manno-2-octulosonate in capsular polysaccharides.
33938	1,6-alpha-L-fucosidase activity	F	Catalysis of the hydrolysis of (1->6) linkages between alpha-L-fucose and N-acetyl-D-glucosamine in glycopeptides such as immunoglobulin G glycopeptide and fucosyl-asialo-agalacto-fetuin.
33939	xylan alpha-1,2-glucuronosidase activity	F	Catalysis of the hydrolysis of alpha-D-(1->2)-(4-O-methyl)glucuronosyl links in the main chain of hardwood xylans.
33940	glucuronoarabinoxylan endo-1,4-beta-xylanase activity	F	Catalysis of the endohydrolysis of (1->4)-beta-D-xylosyl links in some glucuronoarabinoxylans.
33941	mannan exo-1,2-1,6-alpha-mannosidase activity	F	Catalysis of the hydrolysis of (1->2)-alpha-D- and (1->6)-alpha-D- linkages in mannan, releasing D-mannose.
33942	4-alpha-D-{(1->4)-alpha-D-glucano}trehalose trehalohydrolase activity	F	Catalysis of the hydrolysis of alpha-(1->4)-D-glucosidic linkage in 4-alpha-D-{(1->4)-alpha-D-glucanosyl}n trehalose to yield trehalose and alpha-(1->4)-D-glucan.
33943	galactan 1,3-beta-galactosidase activity	F	Catalysis of the hydrolysis of terminal, non-reducing beta-D-galactose residues in (1->3)-beta-D-galactopyranans.
33944	beta-galactofuranosidase activity	F	Catalysis of the hydrolysis of terminal non-reducing beta-D-galactofuranosides, releasing galactose.
33945	oligoxyloglucan reducing-end-specific cellobiohydrolase activity	F	Catalysis of the hydrolysis of cellobiose from the reducing end of xyloglucans consisting of a beta-(1->4) linked glucan carrying alpha-D-xylosyl groups on O-6 of the glucose residues. To be a substrate, the first residue must be unsubstituted, the second residue may bear a xylosyl group, whether further glycosylated or not, and the third residue, which becomes the new terminus by the action of the enzyme, is preferably xylosylated, but this xylose residue must not be further substituted.
33946	xyloglucan-specific endo-beta-1,4-glucanase activity	F	Catalysis of the reaction: xyloglucan + H2O = xyloglucan oligosaccharides. This reaction is the endohydrolysis of (1->4)-beta-D-glucosidic linkages in xyloglucan.
33947	mannosylglycoprotein endo-beta-mannosidase activity	F	Catalysis of the hydrolysis of the alpha-D-mannosyl-(1->6)-beta-D-mannosyl-(1->4)-beta-D-N-acetylglucosaminyl-(1->4)-beta-D-N-acetylglucosaminyl sequence of glycoprotein to alpha-D-mannosyl-(1->6)-D-mannose and beta-D-N-acetylglucosaminyl-(1->4)-beta-D-N-acetylglucosaminyl sequences.
33948	fructan beta-(2,1)-fructosidase activity	F	Catalysis of the hydrolysis of terminal, non-reducing (2->1) linked beta-D-fructofuranose residues in fructans.
33949	fructan beta-(2,6)-fructosidase activity	F	Catalysis of the hydrolysis of terminal, non-reducing (2->6) linked beta-D-fructofuranose residues in fructans.
33950	xyloglucan-specific exo-beta-1,4-glucanase activity	F	Catalysis of the reaction: xyloglucan + H2O = xyloglucan oligosaccharides. This reaction is the exohydrolysis of 1,4-beta-D-glucosidic linkages in xyloglucan.
33951	oligosaccharide reducing-end xylanase activity	F	Catalysis of the hydrolysis of 1,4-beta-D-xylose residues from the reducing end of oligosaccharides.
33952	iota-carrageenase activity	F	Catalysis of the endohydrolysis of 1,4-beta-D-linkages between D-galactose 4-sulfate and 3,6-anhydro-D-galactose-2-sulfate in iota-carrageenans.
33953	alpha-agarase activity	F	Catalysis of the endohydrolysis of 1,3-alpha-L-galactosidic linkages in agarose, yielding agarotetraose as the major product.
33954	alpha-neoagaro-oligosaccharide hydrolase activity	F	Catalysis of the hydrolysis of the 1,3-alpha-L-galactosidic linkages of neoagaro-oligosaccharides that are smaller than a hexamer, yielding 3,6-anhydro-L-galactose and D-galactose.
33955	mitochondrial DNA inheritance	P	The process in which copies of the mitochondrial genome are distributed into daughter mitochondria upon mitochondrial fission.
33956	beta-apiosyl-beta-glucosidase activity	F	Catalysis of the reaction: 7-[beta-D-apiofuranosyl-(1->6)-beta-D-glucopyranosyloxy]isoflavonoid + H2O = a 7-hydroxyisoflavonoid + beta-D-apiofuranosyl-(1->6)-D-glucose.
33957	lambda-carrageenase activity	F	Catalysis of the endohydrolysis of beta-1,4-linkages in the backbone of lambda-carrageenan, resulting in the tetrasaccharide alpha-D-Galp2,6S2-(1->3)-beta-D-Galp2S-(1->4)-alpha-D-Galp2,6S2-(1->3)-D-Galp2S.
33958	DNA-deoxyinosine glycosylase activity	F	Catalysis of the hydrolysis of DNA and polynucleotides, releasing free hypoxanthine.
33959	deoxyribodipyrimidine endonucleosidase activity	F	Catalysis of the cleavage of the N-glycosidic bond between the 5'-pyrimidine residue in cyclobutadipyrimidine (in DNA) and the corresponding deoxy-D-ribose residue.
33960	N-methyl nucleosidase activity	F	Catalysis of the reaction: 7-methylxanthosine + H(2)O = 7-methylxanthine + H(+) + ribofuranose.
33961	cis-stilbene-oxide hydrolase activity	F	Catalysis of the reaction: cis-stilbene oxide + H2O = (+)-(1R,2R)-1,2-diphenylethane-1,2-diol.
33962	cytoplasmic mRNA processing body assembly	P	The aggregation, arrangement and bonding together of proteins and RNA molecules to form a cytoplasmic mRNA processing body.
33963	cholesterol-5,6-oxide hydrolase activity	F	Catalysis of the reactions: 5,6alpha-epoxy-5alpha-cholestan-3beta-ol + H2O = cholestane-3beta-5alpha,6beta-triol, and 5,6beta-epoxy-5beta-cholestan-3beta-ol + H2O = cholestane-3beta-5alpha,6beta-triol.
33964	glycosphingolipid deacylase activity	F	Catalysis of the hydrolysis of gangliosides and neutral glycosphingolipids, releasing fatty acids to form the lyso-derivatives.
33965	aculeacin-A deacylase activity	F	Catalysis of the hydrolysis of the amide bond in aculeacin A and related neutral lipopeptide antibiotics, releasing the long-chain fatty acid side-chain.
33966	N-substituted formamide deformylase activity	F	Catalysis of the reaction: N-benzylformamide + H2O = formate + benzylamine.
33967	box C/D snoRNA metabolic process	P	The chemical reactions and pathways involving box C/D type small nucleolar RNA.
33968	glutaryl-7-aminocephalosporanic-acid acylase activity	F	Catalysis of the reaction: (7R)-7-(4-carboxybutanamido)cephalosporanate + H2O = (7R)-7-aminocephalosporanate + glutarate.
33969	gamma-glutamyl-gamma-aminobutyrate hydrolase activity	F	Catalysis of the reaction: 4-(L-gamma-glutamylamino)butanoate + H(2)O = 4-aminobutanoate + L-glutamate.
33970	N-malonylurea hydrolase activity	F	Catalysis of the reaction: 3-oxo-3-ureidopropanoate + H(2)O = H(+) + malonate + urea.
33971	hydroxyisourate hydrolase activity	F	Catalysis of the reaction: 5-hydroxyisourate + H(2)O = 5-hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate + H(+).
33972	proclavaminate amidinohydrolase activity	F	Catalysis of the reaction: amidinoproclavaminate + H(2)O = proclavaminate + urea.
33973	dCTP deaminase (dUMP-forming) activity	F	Catalysis of the reaction: dCTP + 2 H(2)O = diphosphate + dUMP + H(+) + NH(4)(+).
33974	nucleoside phosphoacylhydrolase activity	F	Catalysis of the hydrolysis of mixed phospho-anhydride bonds.
33975	(R)-2-haloacid dehalogenase activity	F	Catalysis of the reaction: (R)-2-haloacid + H2O = (S)-2-hydroxyacid + halide.
33976	2-haloacid dehalogenase (configuration-inverting) activity	F	Catalysis of the reactions: (S)-2-haloacid + H2O = (R)-2-hydroxyacid + halide, and (R)-2-haloacid + H2O = (S)-2-hydroxyacid + halide.
33977	2-haloacid dehalogenase (configuration-retaining) activity	F	Catalysis of the reactions: (S)-2-haloacid + H2O = (S)-2-hydroxyacid + halide, and (R)-2-haloacid + H2O = (R)-2-hydroxyacid + halide.
33978	phosphonopyruvate hydrolase activity	F	Catalysis of the reaction: 3-phosphonopyruvate + H(2)O = phosphate + pyruvate.
33979	box H/ACA snoRNA metabolic process	P	The chemical reactions and pathways involving box H/ACA type small nucleolar RNA.
33980	phosphonopyruvate decarboxylase activity	F	Catalysis of the reaction: 3-phosphonopyruvate + 2 H(+) = CO(2) + phosphonoacetaldehyde.
33981	D-dopachrome decarboxylase activity	F	Catalysis of the reaction: D-dopachrome + H(+) = 5,6-dihydroxyindole + CO(2).
33982	3-dehydro-L-gulonate-6-phosphate decarboxylase activity	F	Catalysis of the reaction: 3-dehydro-L-gulonate 6-phosphate + H(+) = L-xylulose 5-phosphate + CO(2).
33983	diaminobutyrate decarboxylase activity	F	Catalysis of the reaction: L-2,4-diaminobutyrate + H(+) = 1,3-diaminopropane + CO(2).
33984	indole-3-glycerol-phosphate lyase activity	F	Catalysis of the reaction: (1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate = indole + D-glyceraldehyde 3-phosphate.
33985	acidocalcisome lumen	C	The volume enclosed by the membranes of an acidocalcisome.
33986	response to methanol	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methanol stimulus.
33987	2-hydroxyisoflavanone dehydratase activity	F	Catalysis of the reaction: 2,7,4'-trihydroxyisoflavanone = daidzein + H2O.
33988	bile-acid 7alpha-dehydratase activity	F	Catalysis of the reaction: 7alpha,12alpha-dihydroxy-3-oxochol-4-en-24-oate = 12alpha-hydroxy-3-oxochola-4,6-dien-24-oate + H(2)O.
33989	3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase activity	F	Catalysis of the reaction: (24R,25R)-3alpha,7alpha,12alpha,24-tetrahydroxy-5beta-cholestanoyl-CoA = (24E)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA + H2O.
33990	ectoine synthase activity	F	Catalysis of the reaction: N(4)-acetyl-L-2,4-diaminobutyrate = ectoine + H(2)O.
33991	aldos-2-ulose dehydratase activity	F	Catalysis of the reactions: 1,5-anhydro-D-fructose = 2-hydroxy-2-(hydroxymethyl)-2H-pyran-3(6H)-one + H2O; (1a) 1,5-anhydro-D-fructose = 1,5-anhydro-4-deoxy-D-glycero-hex-3-en-2-ulose + H2O and (1b) 1,5-anhydro-4-deoxy-D-glycero-hex-3-en-2-ulose = 2-hydroxy-2-(hydroxymethyl)-2H-pyran-3(6H)-one.
33992	1,5-anhydro-D-fructose dehydratase activity	F	Catalysis of the reaction: 1,5-anhydro-D-fructose = 1,5-anhydro-4-deoxy-D-glycero-hex-3-en-2-ulose + H2O.
33993	response to lipid	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipid stimulus.
33994	glucuronan lyase activity	F	Catalysis of the reaction: (1->4)-beta-D-glucuronan = an oligosaccharide with 4-deoxy-beta-D-gluc-4-enuronosyl end + (1->4)-beta-D-glucuronan. This reaction is the eliminative cleavage of (1->4)-beta-D-glucuronans to give oligosaccharides with 4-deoxy-beta-D-gluc-4-enuronosyl groups at their non-reducing ends. Complete degradation of glucuronans results in the formation of tetrasaccharides.
33995	anhydrosialidase activity	F	Catalysis of the reaction: an N-acetylneuraminate glycoside = 2,7-anhydro-alpha-N-acetylneuraminate + an alpha-sialyl group. This reaction is the elimination of alpha-sialyl groups in N-acetylneuraminic acid glycosides, releasing 2,7-anhydro-alpha-N-acetylneuraminate.
33996	levan fructotransferase (DFA-IV-forming) activity	F	Catalysis of the reaction: beta-D-fructopyranosyl-(2->6)-[D-fructofuranosyl-(2->6)]n-D-fructofuranoside = beta-D-fructopyranosyl-(2->6)-[D-fructofuranosyl-(2->6)](n-1)-D-fructofuranoside + di-beta-D-fructofuranose 2,6':2',6-dianhydride. This reaction is the production of di-beta-D-fructofuranose 2,6':2',6-dianhydride (DFA IV) by successively eliminating the diminishing (2->6)-beta-D-fructan (levan) chain from the terminal D-fructosyl-D-fructosyl disaccharide.
33997	inulin fructotransferase (DFA-I-forming) activity	F	Catalysis of the reaction: [(2->1)-beta-D-fructosyl](n) = [(2->1)-beta-D-fructosyl](n-1) + alpha-D-fructofuranose-beta-D-fructofuranose 1,2':1,2'-dianhydride. This reaction is the production of alpha-D-fructofuranose beta-D-fructofuranose 1,2':2,1'-dianhydride (DFA I) by successively eliminating the diminishing (2->1)-beta-D-fructan (inulin) chain from the terminal D-fructosyl-D-fructosyl disaccharide.
33998	inulin fructotransferase (DFA-III-forming) activity	F	Catalysis of the reaction: [(2->1)-beta-D-fructosyl](n) = [(2->1)-beta-D-fructosyl](n-1) + alpha-D-fructofuranose beta-D-fructofuranose 1,2':2,3'-dianhydride. This reaction is the production of alpha-D-fructofuranose beta-D-fructofuranose 1,2':2,3'-dianhydride (DFA III) by successively eliminating the diminishing (2->1)-beta-D-fructan (inulin) chain from the terminal D-fructosyl-D-fructosyl disaccharide.
33999	chondroitin B lyase activity	F	Catalysis of the reaction: dermatan sulfate = n 4-deoxy-beta-D-gluc-4-enuronosyl-(1,3)-N-acetyl-D-galactosamine 4-sulfate. This reaction is the eliminative cleavage of dermatan sulfate containing 1,4-beta-D-hexosaminyl and 1,3-beta-D-glucurosonyl or 1,3-alpha-L-iduronosyl linkages to disaccharides containing 4-deoxy-beta-D-gluc-4-enuronosyl groups to yield a 4,5-unsaturated dermatan-sulfate disaccharide (DeltaUA-GalNAC-4S). Chondroitin sulfate B is also known as dermatan sulfate.
34000	chondroitin-sulfate-ABC endolyase activity	F	Catalysis of the endolytic cleavage of beta-1,4-galactosaminic bonds between N-acetylgalactosamine and either D-glucuronic acid or L-iduronic acid to produce a mixture of Delta4-unsaturated oligosaccharides of different sizes that are ultimately degraded to Delta4-unsaturated tetra- and disaccharides.
34001	chondroitin-sulfate-ABC exolyase activity	F	Catalysis of the exolytic cleavage of disaccharide residues from the non-reducing ends of both polymeric chondroitin sulfates and their oligosaccharide fragments.
34002	(R)-limonene synthase activity	F	Catalysis of the reaction: geranyl diphosphate = (4R)-limonene + diphosphate.
34003	vetispiradiene synthase activity	F	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = diphosphate + vetispiradiene.
34004	germacradienol synthase activity	F	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate + H2O = (1E,4S,5E,7R)-germacra-1(10),5-dien-11-ol + diphosphate.
34005	germacrene-A synthase activity	F	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = (+)-(R)-germacrene A + diphosphate.
34006	amorpha-4,11-diene synthase activity	F	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = amorpha-4,11-diene + diphosphate.
34007	S-linalool synthase activity	F	Catalysis of the reaction: geranyl diphosphate + H(2)O = (S)-linalool + diphosphate.
34008	R-linalool synthase activity	F	Catalysis of the reaction: geranyl diphosphate + H(2)O = (R)-linalool + diphosphate.
34009	isoprene synthase activity	F	Catalysis of the reaction: dimethylallyl diphosphate = diphosphate + isoprene.
34010	sulfolactate sulfo-lyase activity	F	Catalysis of the reaction: 3-sulfolactate = pyruvate + sulfite.
34011	L-cysteate sulfo-lyase activity	F	Catalysis of the reaction: L-cysteate + H(2)O = NH(4)(+) + pyruvate + sulfite.
34012	FAD-AMP lyase (cyclizing) activity	F	Catalysis of the reaction: FAD = AMP + riboflavin cyclic-4',5'-phosphate.
34013	aliphatic aldoxime dehydratase activity	F	Catalysis of the reaction: an aliphatic aldoxime = an aliphatic nitrile + H2O.
34014	response to triglyceride	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a triglyceride stimulus.
34015	L-ribulose-5-phosphate 3-epimerase activity	F	Catalysis of the reaction: L-ribulose 5-phosphate = L-xylulose 5-phosphate.
34016	polyenoic fatty acid isomerase activity	F	Catalysis of the reaction: all-cis-icosa-5,8,11,14,17-pentaenoate = (5Z,7E,9E,14Z,17Z)-icosapentaenoate.
34017	trans-2-decenoyl-acyl-carrier-protein isomerase activity	F	Catalysis of the reaction: trans-dec-2-enoyl-[acyl-carrier protein] = cis-dec-3-enoyl-[acyl-carrier protein].
34018	ascopyrone tautomerase activity	F	Catalysis of the reaction: 1,5-anhydro-4-deoxy-D-glycero-hex-3-en-2-ulose = 1,5-anhydro-4-deoxy-D-glycero-hex-1-en-3-ulose.
34020	neoxanthin synthase activity	F	Catalysis of the reaction: all-trans-violaxanthin = all-trans-neoxanthin.
34021	response to silicon dioxide	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a silicon dioxide stimulus.
34022	3-(hydroxyamino)phenol mutase activity	F	Catalysis of the reaction: 3-hydroxyaminophenol = aminohydroquinone.
34023	5-(carboxyamino)imidazole ribonucleotide mutase activity	F	Catalysis of the reaction: 5-carboxyamino-1-(5-phospho-D-ribosyl)imidazole = 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate.
34024	glutamate-putrescine ligase activity	F	Catalysis of the reaction: L-glutamate + ATP + putrescine = gamma-L-glutamylputrescine + ADP + 2 H(+) + phosphate.
34025	D-aspartate ligase activity	F	Catalysis of the reaction: ATP + D-aspartate + [beta-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)]n = [beta-GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-6-N-(beta-D-Asp)-L-Lys-D-Ala-D-Ala)]n + ADP + phosphate.
34026	L-amino-acid alpha-ligase activity	F	Catalysis of the reaction: ATP + an L-amino acid + an L-amino acid = ADP + phosphate + L-aminoacyl-L-amino acid.
34027	(carboxyethyl)arginine beta-lactam-synthase activity	F	Catalysis of the reaction: N(2)-(2-carboxyethyl)-L-arginine + ATP = AMP + deoxyamidinoproclavaminate + diphosphate + 2 H(+).
34028	5-(carboxyamino)imidazole ribonucleotide synthase activity	F	Catalysis of the reaction: 5-amino-1-(5-phospho-D-ribosyl)imidazole + ATP + bicarbonate = 5-carboxyamino-1-(5-phospho-D-ribosyl)imidazole + ADP + 3 H(+) + phosphate.
34029	2-oxoglutarate carboxylase activity	F	Catalysis of the reaction: 2-oxoglutarate + ATP + bicarbonate = ADP + 2 H(+) + oxalosuccinate + phosphate.
34030	ribonucleoside bisphosphate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of a ribonucleoside bisphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar.
34031	ribonucleoside bisphosphate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of a ribonucleoside bisphosphate, a compound consisting of a nucleobase linked to a ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar.
34032	purine nucleoside bisphosphate metabolic process	P	The chemical reactions and pathways involving a purine nucleoside bisphosphate, a compound consisting of a purine base linked to a deoxyribose or ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar.
34033	purine nucleoside bisphosphate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of a purine nucleoside bisphosphate, a compound consisting of a purine base linked to a deoxyribose or ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar.
34034	purine nucleoside bisphosphate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of a purine nucleoside bisphosphate, a compound consisting of a purine base linked to a deoxyribose or ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar.
34035	purine ribonucleoside bisphosphate metabolic process	P	The chemical reactions and pathways involving a purine ribonucleoside bisphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar.
34036	purine ribonucleoside bisphosphate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of a purine ribonucleoside bisphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar.
34037	purine ribonucleoside bisphosphate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of a purine ribonucleoside bisphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with one phosphate group attached to each of two different hydroxyl groups on the sugar.
34038	deoxyhypusine synthase activity	F	Catalysis of the reaction: [eIF5A-precursor]-lysine + spermidine = [eIF5A-precursor]-deoxyhypusine + propane-1,3-diamine. Four sub-reactions have been identified,in which the intermediates remain tightly associated with the enzyme: spermidine + NAD+ = dehydrospermidine + NADH; dehydrospermidine + [enzyme]-lysine = N-(4-aminobutylidene)-[enzyme]-lysine + propane-1,3-diamine; N-(4-aminobutylidene)-[enzyme]-lysine + [eIF5A-precursor]-lysine = N-(4-aminobutylidene)-[eIF5A-precursor]-lysine + [enzyme]-lysine; N-(4-aminobutylidene)-[eIF5A-precursor]-lysine + NADH + H+ = [eIF5A-precursor]-deoxyhypusine + NAD+.
34039	8-oxo-7,8-dihydroguanine DNA N-glycosylase activity	F	Catalysis of the removal of 8-oxo-7,8-dihydroguanine bases by cleaving the N-C1' glycosidic bond between the oxidized purine and the deoxyribose sugar.
34040	lipid-transporting ATPase activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + lipid(in) = ADP + phosphate + lipid(out).
34041	sterol-transporting ATPase activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + sterol(in) = ADP + phosphate + sterol(out).
34042	5-formyluracil DNA N-glycosylase activity	F	Catalysis of the removal of 5-formyluracil bases by cleaving the N-C1' glycosidic bond between the oxidized pyrimidine and the deoxyribose sugar.
34043	5-hydroxymethyluracil DNA N-glycosylase activity	F	Catalysis of the removal of 5-hydroxymethyluracil bases by cleaving the N-C1' glycosidic bond between the oxidized pyrimidine and the deoxyribose sugar.
34044	exomer complex	C	A protein complex that forms a coat structure on vesicles involved in exocytosis of proteins from the trans-Golgi network to the cell surface; in Saccharomyces, the complex contains Chs5p, Chs6p, and Chs6p paralogues.
34045	pre-autophagosomal structure membrane	C	A cellular membrane associated with the pre-autophagosomal structure.
34046	poly(G) binding	F	Interacting selectively and non-covalently with a sequence of guanine residues in an RNA molecule.
34047	regulation of protein phosphatase type 2A activity	P	Any process that modulates the activity of the enzyme protein phosphatase type 2A.
34048	negative regulation of protein phosphatase type 2A activity	P	Any process that stops or reduces the activity of the enzyme protein phosphatase type 2A.
34049	positive regulation of protein phosphatase type 2A activity	P	Any process that activates or increases the activity of the enzyme protein phosphatase type 2A.
34050	host programmed cell death induced by symbiont	P	Cell death in a host resulting from activation of host endogenous cellular processes after direct or indirect interaction with a symbiont (defined as the smaller of two, or more, organisms engaged in symbiosis, a close interaction encompassing mutualism through parasitism). An example of direct interaction is contact with penetrating hyphae of a fungus; an example of indirect interaction is encountering symbiont-secreted molecules.
34051	negative regulation of plant-type hypersensitive response	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the hypersensitive response in a plant.
34052	positive regulation of plant-type hypersensitive response	P	Any process that activates or increases the frequency, rate or extent of the hypersensitive response in a plant.
34053	modulation by symbiont of host defense-related programmed cell death	P	Any process in which an organism modulates the frequency, rate or extent of defense-related programmed cell death in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
34054	negative regulation by symbiont of host defense-related programmed cell death	P	Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of defense-related programmed cell death in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
34055	positive regulation by symbiont of host defense-related programmed cell death	P	Any process in which an organism activates or increases the frequency, rate or extent of defense-related programmed cell death in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
34056	estrogen response element binding	F	Interacting selectively and non-covalently with the estrogen response element (ERE), a conserved sequence found in the promoters of genes whose expression is regulated in response to estrogen.
34057	RNA strand-exchange activity	F	Facilitates the displacement of one strand of an RNA-RNA duplex and its replacement with a different strand of higher complementarity.
34058	endosomal vesicle fusion	P	The homotypic fusion of endocytic vesicles to form or add to an early endosome.
34059	response to anoxia	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating a decline in oxygen levels to trace amounts, <0.1%.
34060	cyanelle stroma	C	The space enclosed by the double membrane of a cyanelle.
34061	DNA polymerase activity	F	Catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1); the synthesis of DNA from deoxyribonucleotide triphosphates in the presence of a nucleic acid template and a 3'hydroxyl group.
34062	5'-3' RNA polymerase activity	F	Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1); the synthesis of RNA from ribonucleotide triphosphates in the presence of a nucleic acid template, via extension of the 3'-end.
34063	stress granule assembly	P	The aggregation, arrangement and bonding together of proteins and RNA molecules to form a stress granule.
34064	Tor2-Mei2-Ste11 complex	C	A protein complex that contains the transcription factor Ste11 and the RNA binding protein Mei2; involved in regulation of conjugation in fission yeast.
34065	replication fork processing at rDNA locus	P	The process in which a DNA replication fork that has stalled at the rDNA replication fork barrier (RFB) is repaired and replication is restarted.
34066	RIC1-RGP1 guanyl-nucleotide exchange factor complex	C	A protein complex that acts as a nucleotide exchange factor for the GTPase Ypt6p, and is required for fusion of endosome-derived vesicles with the Golgi.
34067	protein localization to Golgi apparatus	P	A process in which a protein is transported to, or maintained in, a location within the Golgi apparatus.
34068	aminoglycoside nucleotidyltransferase activity	F	Catalysis of the reaction: nucleoside triphosphate + aminoglycoside = diphosphate + nucleotidylaminoglycoside.
34069	aminoglycoside N-acetyltransferase activity	F	Catalysis of the reaction: acetyl-CoA + aminoglycoside = CoA + N-acetylaminoglycoside.
34070	aminoglycoside 1-N-acetyltransferase activity	F	Catalysis of the reaction: acetyl-CoA + aminoglycoside = CoA + 1-N-acetylaminoglycoside. This is acetylation of the 1-amino group of the central deoxystreptamine ring.
34071	aminoglycoside phosphotransferase activity	F	Catalysis of the reaction: ATP + aminoglycoside = ADP + phosphoaminoglycoside.
34072	squalene cyclase activity	F	Catalysis of the reaction: squalene = triterpene.
34073	tetrahymanol cyclase activity	F	Catalysis of the reaction: squalene = tetrahymanol.
34074	marneral synthase activity	F	Catalysis of the reaction: oxidosqualene = marneral.
34075	arabidiol synthase activity	F	Catalysis of the reaction: oxidosqualene + H2O = arabidiol ((13R,14R,17E)-malabarica-17,21-diene-3beta,14-diol).
34076	cucurbitadienol synthase activity	F	Catalysis of the reaction: oxidosqualene = cucurbitadienol.
34077	butanediol metabolic process	P	The chemical reactions and pathways involving butanediol; the biologically relevant isomer is 2,3-butanediol, CH3CH(OH)CH(OH)CH3.
34078	butanediol catabolic process	P	The chemical reactions and pathways resulting in the breakdown of butanediol; the biologically relevant isomer is 2,3-butanediol, CH3CH(OH)CH(OH)CH3.
34079	butanediol biosynthetic process	P	The chemical reactions and pathways resulting in the formation of butanediol; the biologically relevant isomer is 2,3-butanediol, CH3CH(OH)CH(OH)CH3.
34080	CENP-A containing nucleosome assembly	P	The formation of nucleosomes containing the histone H3 variant CENP-A to form centromeric chromatin. This specialised chromatin occurs at centromeric region in point centromeres, and the central core in modular centromeres.
34081	polyketide synthase complex	C	A protein complex that carries out enzymatic reactions involved in the biosynthesis of polyketides, any of a diverse group of natural products synthesized via linear poly-beta-ketones.
34082	type II polyketide synthase complex	C	A polyketide synthase complex that consists of several different polypeptide chains, each of which catalyzes a single reaction.
34083	type III polyketide synthase complex	C	A polyketide synthase complex that consists of two identical ketosynthase polypeptides.
34084	steryl deacetylase activity	F	Catalysis of the hydrolysis of an acetyl group or groups from an acetylated sterol.
34085	establishment of sister chromatid cohesion	P	The process in which the sister chromatids of a replicated chromosome become associated with each other during S phase.
34086	maintenance of sister chromatid cohesion	P	The process in which the association between sister chromatids of a replicated chromosome is maintained as chromosomes condense, attach to the spindle in a bipolar orientation, and congress to the metaphase plate.
34087	establishment of mitotic sister chromatid cohesion	P	The process in which the sister chromatids of a replicated chromosome become joined along the entire length of the chromosome during S phase during a mitotic cell cycle.
34088	maintenance of mitotic sister chromatid cohesion	P	The process in which the association between sister chromatids of a replicated chromosome is maintained as chromosomes condense, attach to the spindle in a bipolar orientation, and congress to the metaphase plate during a mitotic cell cycle.
34089	establishment of meiotic sister chromatid cohesion	P	The process in which the sister chromatids of a replicated chromosome become joined along the entire length of the chromosome during S phase during a meiotic cell cycle.
34090	maintenance of meiotic sister chromatid cohesion	P	The process in which the association between sister chromatids of a replicated chromosome is maintained as chromosomes condense, attach to the spindle in a bipolar orientation, and congress to the metaphase plate during a meiotic cell cycle.
34091	regulation of maintenance of sister chromatid cohesion	P	Any process that modulates the extent to which the association between sister chromatids of a replicated chromosome is maintained.
34092	negative regulation of maintenance of sister chromatid cohesion	P	Any process that decreases the extent to which the association between sister chromatids of a replicated chromosome is maintained.
34093	positive regulation of maintenance of sister chromatid cohesion	P	Any process that increases the extent to which the association between sister chromatids of a replicated chromosome is maintained.
34094	regulation of maintenance of meiotic sister chromatid cohesion	P	Any process that modulates the extent to which the association between sister chromatids of a replicated chromosome is maintained during a meiotic cell cycle.
34095	negative regulation of maintenance of meiotic sister chromatid cohesion	P	Any process that decreases the extent to which the association between sister chromatids of a replicated chromosome is maintained during a meiotic cell cycle.
34096	positive regulation of maintenance of meiotic sister chromatid cohesion	P	Any process that increases the extent to which the association between sister chromatids of a replicated chromosome is maintained during a meiotic cell cycle.
34097	response to cytokine	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytokine stimulus.
34098	VCP-NPL4-UFD1 AAA ATPase complex	C	A multiprotein ATPase complex required for the efficient dislocation of ER-lumenal degradation substrates, and their subsequent proteolysis by the proteasome. In budding yeast, this complex includes Cdc48p, Npl4p and Ufd1p proteins. In mammals, this complex includes a hexamer of VCP/p97 (a cytosolic ATPase) and trimers of each of its cofactors UFD1L and NPL4 (NPLOC4) (e.g. a 6:3:3 stoichiometry).
34099	luminal surveillance complex	C	A multiprotein complex that recognizes ERAD-luminal misfolded substrates and brings them to the ubiquitination/extraction machinery. In yeast, this complex consists of Yos9p, Kar2p and Hrd3p proteins.
34101	erythrocyte homeostasis	P	Any process of regulating the production and elimination of erythrocytes within an organism.
34102	erythrocyte clearance	P	The selective elimination of erythrocytes from the body by autoregulatory mechanisms.
34103	regulation of tissue remodeling	P	Any process that modulates the frequency, rate, or extent of tissue remodeling.
34104	negative regulation of tissue remodeling	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of tissue remodeling.
34105	positive regulation of tissue remodeling	P	Any process that activates or increases the frequency, rate, or extent of tissue remodeling.
34106	regulation of erythrocyte clearance	P	Any process that modulates the frequency, rate, or extent of erythrocyte clearance.
34107	negative regulation of erythrocyte clearance	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of erythrocyte clearance.
34108	positive regulation of erythrocyte clearance	P	Any process that activates or increases the frequency, rate, or extent of erythrocyte clearance.
34109	homotypic cell-cell adhesion	P	The attachment of a cell to a second cell of the identical type via adhesion molecules.
34110	regulation of homotypic cell-cell adhesion	P	Any process that modulates the frequency, rate, or extent of homotypic cell-cell adhesion.
34111	negative regulation of homotypic cell-cell adhesion	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of homotypic cell-cell adhesion.
34112	positive regulation of homotypic cell-cell adhesion	P	Any process that activates or increases the frequency, rate, or extent of homotypic cell-cell adhesion.
34113	heterotypic cell-cell adhesion	P	The attachment of a cell to a cell of a different type via adhesion molecules.
34114	regulation of heterotypic cell-cell adhesion	P	Any process that modulates the frequency, rate, or extent of heterotypic cell-cell adhesion.
34115	negative regulation of heterotypic cell-cell adhesion	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of heterotypic cell-cell adhesion.
34116	positive regulation of heterotypic cell-cell adhesion	P	Any process that activates or increases the frequency, rate, or extent of heterotypic cell-cell adhesion.
34117	erythrocyte aggregation	P	The adhesion of one erythrocyte to one or more other erythrocytes via adhesion molecules.
34118	regulation of erythrocyte aggregation	P	Any process that modulates the frequency, rate, or extent of erythrocyte aggregation.
34119	negative regulation of erythrocyte aggregation	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of erythrocyte aggregation.
34120	positive regulation of erythrocyte aggregation	P	Any process that activates or increases the frequency, rate, or extent of erythrocyte aggregation.
34121	regulation of toll-like receptor signaling pathway	P	Any process that modulates the frequency, rate, or extent of toll-like receptor signaling pathway.
34122	negative regulation of toll-like receptor signaling pathway	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor signaling pathway.
34123	positive regulation of toll-like receptor signaling pathway	P	Any process that activates or increases the frequency, rate, or extent of toll-like receptor signaling pathway.
34124	regulation of MyD88-dependent toll-like receptor signaling pathway	P	Any process that modulates the frequency, rate, or extent of MyD88-dependent toll-like receptor signaling pathway.
34125	negative regulation of MyD88-dependent toll-like receptor signaling pathway	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of MyD88-dependent toll-like receptor signaling pathway.
34126	positive regulation of MyD88-dependent toll-like receptor signaling pathway	P	Any process that activates or increases the frequency, rate, or extent of MyD88-dependent toll-like receptor signaling pathway.
34127	regulation of MyD88-independent toll-like receptor signaling pathway	P	Any process that modulates the frequency, rate, or extent of MyD88-independent toll-like receptor signaling pathway.
34128	negative regulation of MyD88-independent toll-like receptor signaling pathway	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of MyD88-independent toll-like receptor signaling pathway.
34129	positive regulation of MyD88-independent toll-like receptor signaling pathway	P	Any process that activates or increases the frequency, rate, or extent of MyD88-independent toll-like receptor signaling pathway.
34130	toll-like receptor 1 signaling pathway	P	Any series of molecular signals generated as a consequence of binding to toll-like receptor 1.
34131	regulation of toll-like receptor 1 signaling pathway	P	Any process that modulates the frequency, rate, or extent of toll-like receptor 1 signaling pathway.
34132	negative regulation of toll-like receptor 1 signaling pathway	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 1 signaling pathway.
34133	positive regulation of toll-like receptor 1 signaling pathway	P	Any process that activates or increases the frequency, rate, or extent of toll-like receptor 1 signaling pathway.
34134	toll-like receptor 2 signaling pathway	P	Any series of molecular signals generated as a consequence of binding to toll-like receptor 2.
34135	regulation of toll-like receptor 2 signaling pathway	P	Any process that modulates the frequency, rate, or extent of toll-like receptor 2 signaling pathway.
34136	negative regulation of toll-like receptor 2 signaling pathway	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 2 signaling pathway.
34137	positive regulation of toll-like receptor 2 signaling pathway	P	Any process that activates or increases the frequency, rate, or extent of toll-like receptor 2 signaling pathway.
34138	toll-like receptor 3 signaling pathway	P	Any series of molecular signals generated as a consequence of binding to toll-like receptor 3.
34139	regulation of toll-like receptor 3 signaling pathway	P	Any process that modulates the frequency, rate, or extent of toll-like receptor 3 signaling pathway.
34140	negative regulation of toll-like receptor 3 signaling pathway	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 3 signaling pathway.
34141	positive regulation of toll-like receptor 3 signaling pathway	P	Any process that activates or increases the frequency, rate, or extent of toll-like receptor 3 signaling pathway.
34142	toll-like receptor 4 signaling pathway	P	Any series of molecular signals generated as a consequence of binding to toll-like receptor 4.
34143	regulation of toll-like receptor 4 signaling pathway	P	Any process that modulates the frequency, rate, or extent of toll-like receptor 4 signaling pathway.
34144	negative regulation of toll-like receptor 4 signaling pathway	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 4 signaling pathway.
34145	positive regulation of toll-like receptor 4 signaling pathway	P	Any process that activates or increases the frequency, rate, or extent of toll-like receptor 4 signaling pathway.
34146	toll-like receptor 5 signaling pathway	P	Any series of molecular signals generated as a consequence of binding to toll-like receptor 5.
34147	regulation of toll-like receptor 5 signaling pathway	P	Any process that modulates the frequency, rate, or extent of toll-like receptor 5 signaling pathway.
34148	negative regulation of toll-like receptor 5 signaling pathway	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 5 signaling pathway.
34149	positive regulation of toll-like receptor 5 signaling pathway	P	Any process that activates or increases the frequency, rate, or extent of toll-like receptor 5 signaling pathway.
34150	toll-like receptor 6 signaling pathway	P	Any series of molecular signals generated as a consequence of binding to toll-like receptor 6.
34151	regulation of toll-like receptor 6 signaling pathway	P	Any process that modulates the frequency, rate, or extent of toll-like receptor 6 signaling pathway.
34152	negative regulation of toll-like receptor 6 signaling pathway	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 6 signaling pathway.
34153	positive regulation of toll-like receptor 6 signaling pathway	P	Any process that activates or increases the frequency, rate, or extent of toll-like receptor 6 signaling pathway.
34154	toll-like receptor 7 signaling pathway	P	Any series of molecular signals generated as a consequence of binding to toll-like receptor 7.
34155	regulation of toll-like receptor 7 signaling pathway	P	Any process that modulates the frequency, rate, or extent of toll-like receptor 7 signaling pathway.
34156	negative regulation of toll-like receptor 7 signaling pathway	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 7 signaling pathway.
34157	positive regulation of toll-like receptor 7 signaling pathway	P	Any process that activates or increases the frequency, rate, or extent of toll-like receptor 7 signaling pathway.
34158	toll-like receptor 8 signaling pathway	P	Any series of molecular signals generated as a consequence of binding to toll-like receptor 8.
34159	regulation of toll-like receptor 8 signaling pathway	P	Any process that modulates the frequency, rate, or extent of toll-like receptor 8 signaling pathway.
34160	negative regulation of toll-like receptor 8 signaling pathway	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 8 signaling pathway.
34161	positive regulation of toll-like receptor 8 signaling pathway	P	Any process that activates or increases the frequency, rate, or extent of toll-like receptor 8 signaling pathway.
34162	toll-like receptor 9 signaling pathway	P	Any series of molecular signals generated as a consequence of binding to toll-like receptor 9.
34163	regulation of toll-like receptor 9 signaling pathway	P	Any process that modulates the frequency, rate, or extent of toll-like receptor 9 signaling pathway.
34164	negative regulation of toll-like receptor 9 signaling pathway	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 9 signaling pathway.
34165	positive regulation of toll-like receptor 9 signaling pathway	P	Any process that activates or increases the frequency, rate, or extent of toll-like receptor 9 signaling pathway.
34166	toll-like receptor 10 signaling pathway	P	Any series of molecular signals generated as a consequence of binding to toll-like receptor 10.
34167	regulation of toll-like receptor 10 signaling pathway	P	Any process that modulates the frequency, rate, or extent of toll-like receptor 10 signaling pathway.
34168	negative regulation of toll-like receptor 10 signaling pathway	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 10 signaling pathway.
34169	positive regulation of toll-like receptor 10 signaling pathway	P	Any process that activates or increases the frequency, rate, or extent of toll-like receptor 10 signaling pathway.
34170	toll-like receptor 11 signaling pathway	P	Any series of molecular signals generated as a consequence of binding to toll-like receptor 11.
34171	regulation of toll-like receptor 11 signaling pathway	P	Any process that modulates the frequency, rate, or extent of toll-like receptor 11 signaling pathway.
34172	negative regulation of toll-like receptor 11 signaling pathway	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 11 signaling pathway.
34173	positive regulation of toll-like receptor 11 signaling pathway	P	Any process that activates or increases the frequency, rate, or extent of toll-like receptor 11 signaling pathway.
34174	toll-like receptor 12 signaling pathway	P	Any series of molecular signals generated as a consequence of binding to toll-like receptor 12.
34175	regulation of toll-like receptor 12 signaling pathway	P	Any process that modulates the frequency, rate, or extent of toll-like receptor 12 signaling pathway.
34176	negative regulation of toll-like receptor 12 signaling pathway	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 12 signaling pathway.
34177	positive regulation of toll-like receptor 12 signaling pathway	P	Any process that activates or increases the frequency, rate, or extent of toll-like receptor 12 signaling pathway.
34178	toll-like receptor 13 signaling pathway	P	Any series of molecular signals generated as a consequence of binding to toll-like receptor 13.
34179	regulation of toll-like receptor 13 signaling pathway	P	Any process that modulates the frequency, rate, or extent of toll-like receptor 13 signaling pathway.
34180	negative regulation of toll-like receptor 13 signaling pathway	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of toll-like receptor 13 signaling pathway.
34181	positive regulation of toll-like receptor 13 signaling pathway	P	Any process that activates or increases the frequency, rate, or extent of toll-like receptor 13 signaling pathway.
34182	regulation of maintenance of mitotic sister chromatid cohesion	P	Any process that modulates the extent to which the association between sister chromatids of a replicated chromosome is maintained during a mitotic cell cycle.
34183	negative regulation of maintenance of mitotic sister chromatid cohesion	P	Any process that decreases the extent to which the association between sister chromatids of a replicated chromosome is maintained during a mitotic cell cycle.
34184	positive regulation of maintenance of mitotic sister chromatid cohesion	P	Any process that increases the extent to which the association between sister chromatids of a replicated chromosome is maintained during a mitotic cell cycle.
34185	apolipoprotein binding	F	Interacting selectively and non-covalently with an apolipoprotein, the protein component of a lipoprotein complex.
34186	apolipoprotein A-I binding	F	Interacting selectively and non-covalently with apolipoprotein A-I.
34188	apolipoprotein A-I receptor activity	F	Combining with apolipoprotein A-I and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
34189	very-low-density lipoprotein particle binding	F	Interacting selectively and non-covalently with a very-low-density lipoprotein particle, a triglyceride-rich lipoprotein particle that is typically composed of APOB100, APOE and APOCs and has a density of about 1.006 g/ml and a diameter of between 20-80 nm.
34190	apolipoprotein receptor binding	F	Interacting selectively and non-covalently with an apolipoprotein receptor.
34191	apolipoprotein A-I receptor binding	F	Interacting selectively and non-covalently with an apolipoprotein A-I receptor.
34192	D-galactonate metabolic process	P	The chemical reactions and pathways involving D-galactonate, the anion of D-galactonic acid.
34193	L-galactonate metabolic process	P	The chemical reactions and pathways involving L-galactonate, the anion of L-galactonic acid.
34194	D-galactonate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of D-galactonate, the anion of D-galactonic acid.
34195	L-galactonate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of L-galactonate, the anion of L-galactonic acid.
34196	acylglycerol transport	P	The directed movement of an acylglycerol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. An acylglycerol is any mono-, di- or triester of glycerol with (one or more) fatty acids.
34197	triglyceride transport	P	The directed movement of triglyceride into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Triglycerides are important components of plant oils, animal fats and animal plasma lipoproteins.
34198	cellular response to amino acid starvation	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of amino acids.
34199	activation of protein kinase A activity	P	Any process that initiates the activity of the inactive enzyme protein kinase A.
34200	D,D-heptose 1,7-bisphosphate phosphatase activity	F	Catalysis of the reaction: D-beta-D-heptose 1,7-bisphosphate + H2O = D-beta-D-heptose 1-phosphate + phosphate.
34201	response to oleic acid	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oleic acid stimulus.
34202	glycolipid-translocating activity	F	Catalysis of the movement of glycolipids from one membrane face to the other (glycolipid 'flippase' activity).
34203	glycolipid translocation	P	The translocation, or flipping, of glycolipid molecules from one monolayer of a membrane bilayer to the opposite monolayer.
34204	lipid translocation	P	The translocation, or flipping, of lipid molecules from one monolayer of a membrane bilayer to the opposite monolayer.
34205	beta-amyloid formation	P	The generation of beta-amyloid by cleavage of the amyloid precursor protein (APP).
34206	enhanceosome	C	A protein-DNA complex formed by the association of a distinct set of general and specific transcription factors with a region of enhancer DNA. The cooperative assembly of an enhanceosome confers specificity of transcriptional regulation.
34207	steroid acetylation	P	The addition of an acetyl group to a steroid molecule. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid.
34208	steroid deacetylation	P	The removal of an acetyl group from a steroid molecule. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid.
34209	sterol acetylation	P	The addition of an acetyl group to a sterol molecule. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid.
34210	sterol deacetylation	P	The removal of an acetyl group from a sterol molecule. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid.
34211	GTP-dependent protein kinase activity	F	Catalysis of the reaction: ATP + a protein serine/threonine = ADP + protein serine/threonine phosphate, dependent on the presence of GTP.
34212	peptide N-acetyltransferase activity	F	Catalysis of the acetylation of an amino acid residue of a peptide or protein, according to the reaction: acetyl-CoA + peptide = CoA + N-acetylpeptide.
34213	quinolinate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of quinolinate, the anion of quinolinic acid, also known as 2,3-pyridinedicarboxylic acid.
34214	protein hexamerization	P	The formation of a protein hexamer, a macromolecular structure consisting of six noncovalently associated identical or nonidentical subunits.
34215	thiamine:proton symporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: thiamine(out) + H+(out) = thiamine(in) + H+(in).
34216	high-affinity thiamine:proton symporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: thiamine(out) + H+(out) = thiamine(in) + H+(in). In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.
34217	ascospore wall chitin biosynthetic process	P	The chemical reactions and pathways resulting in the formation of ascospore wall chitin, a linear polysaccharide consisting of P-1,4-linked N-acetyl-D-glucosamine residues, found in the walls of ascospores.
34218	ascospore wall chitin metabolic process	P	The chemical reactions and pathways involving ascospore wall chitin, a linear polysaccharide consisting of P-1,4-linked N-acetyl-D-glucosamine residues, found in the walls of ascospores.
34219	carbohydrate transmembrane transport	P	The process in which a carbohydrate is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.
34220	ion transmembrane transport	P	A process in which an ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.
34221	fungal-type cell wall chitin biosynthetic process	P	The chemical reactions and pathways resulting in the formation of cell wall chitin, a linear polysaccharide consisting of P-1,4-linked N-acetyl-D-glucosamine residues, found in the walls of fungal cells.
34222	regulation of cell wall chitin metabolic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving chitin in a cell wall.
34223	regulation of ascospore wall chitin biosynthetic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of ascospore wall chitin.
34224	cellular response to zinc ion starvation	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of zinc ions.
34225	regulation of transcription from RNA polymerase II promoter in response to zinc ion starvation	P	Modulation of the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating the organism is deprived of zinc ions.
34226	lysine import	P	The directed movement of lysine, 2,6-diaminohexanoic acid, into a cell or organelle.
34227	tRNA thio-modification	P	The addition a sulfur atom to a nucleotide in a tRNA molecule.
34228	ethanolamine transmembrane transporter activity	F	Enables the transfer of ethanolamine from one side of the membrane to the other. Ethanolamine (2-aminoethanol, monoethanolamine) is an amino alcohol that occurs widely in living organisms as a constituent of certain types of phospholipids, such as phosphatidylethanolamine.
34229	ethanolamine transport	P	The directed movement of ethanolamine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Ethanolamine (2-aminoethanol, monoethanolamine) is an amino alcohol that occurs widely in living organisms as a constituent of certain types of phospholipids, such as phosphatidylethanolamine.
34230	enkephalin processing	P	The formation of mature enkephalin, a pentapeptide hormone involved in regulating pain and nociception in the body by proteolytic processing of enkephalin propeptide.
34231	islet amyloid polypeptide processing	P	The formation of mature islet amyloid polypeptide (IAPP) by posttranslational processing of pro-islet amyloid polypeptide (pro-IAPP).
34232	ascospore wall chitin catabolic process	P	The chemical reactions and pathways resulting in the breakdown of ascospore wall chitin, a linear polysaccharide consisting of P-1,4-linked N-acetyl-D-glucosamine residues, found in the walls of ascospores.
34233	regulation of cell wall chitin catabolic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of cell wall chitin.
34234	regulation of ascospore wall chitin catabolic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of ascospore wall chitin.
34235	GPI anchor binding	F	Interacting selectively and non-covalently with any glycosylphosphatidylinositol anchor. GPI anchors serve to attach membrane proteins to the lipid bilayer of cell membranes.
34236	protein kinase A catalytic subunit binding	F	Interacting selectively and non-covalently with one or both of the catalytic subunits of protein kinase A.
34237	protein kinase A regulatory subunit binding	F	Interacting selectively and non-covalently with one or both of the regulatory subunits of protein kinase A.
34238	macrophage fusion	P	The binding and fusion of a macrophage to one or more other cells to form a multinucleated cell.
34239	regulation of macrophage fusion	P	Any process that modulates the frequency, rate or extent of macrophage fusion.
34240	negative regulation of macrophage fusion	P	Any process that stops, prevents, or decreases the frequency, rate or extent of macrophage fusion.
34241	positive regulation of macrophage fusion	P	Any process that activates or increases the frequency, rate or extent of macrophage fusion.
34242	negative regulation of syncytium formation by plasma membrane fusion	P	Any process that decreases the frequency, rate or extent of the formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells.
34243	regulation of transcription elongation from RNA polymerase II promoter	P	Any process that modulates the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides, catalyzed by RNA polymerase II.
34244	negative regulation of transcription elongation from RNA polymerase II promoter	P	Any process that stops, prevents, or reduces the frequency, rate or extent of transcription elongation, the extension of an RNA molecule after transcription initiation and promoter clearance by the addition of ribonucleotides, catalyzed by RNA polymerase II.
34245	mitochondrial DNA-directed RNA polymerase complex	C	A DNA-directed RNA polymerase complex located in the mitochondrion. Mitochondrial RNA polymerase is composed of two subunits, a catalytic core, which resembles the enzymes from bacteriophage T7 and T3, and a specificity factor required for promoter recognition, which is similar to members of the eubacterial sigma factor family. In S. cerevisiae, these are encoded by the nuclear genes RPO41 and MTF1 and the specificity factor, required for promoter recognition and initiation, is not present in the elongating form.
34246	mitochondrial RNA polymerase binding promoter specificity activity	F	Interacting selectively and non-covalently with a mitochondrial RNA polymerase to form a holoenzyme complex and also, while present in the holoenzyme, interacting with promoter sequences in order to confer sequence specific recognition of mitochondrial promoter DNA sequence motifs.
34247	snoRNA splicing	P	The process of removing sections of a primary snoRNA transcript to remove sequences not present in the mature form of the snoRNA and joining the remaining sections to form the mature form of the snoRNA.
34248	regulation of cellular amide metabolic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving amides.
34249	negative regulation of cellular amide metabolic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving amides.
34250	positive regulation of cellular amide metabolic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving amides.
34251	regulation of cellular amide catabolic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of amides.
34252	negative regulation of cellular amide catabolic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of amides.
34253	positive regulation of cellular amide catabolic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of amides.
34254	regulation of urea catabolic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of urea.
34255	regulation of urea metabolic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving urea.
34256	chlorophyll(ide) b reductase activity	F	Catalysis of the reaction: 71-hydroxychlorophyll(ide) a + NAD(P)+ = chlorophyll(ide) b + NAD(P)H + H+.
34257	nicotinamide riboside transmembrane transporter activity	F	Enables the transfer of nicotinamide riboside, which is a pyridine-3-carboxamide covalently bonded to a ribose sugar, from one side of a membrane to the other.
34258	nicotinamide riboside transport	P	The directed movement of a nicotinamide riboside, which is a pyridine-3-carboxamide covalently bonded to a ribose sugar, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
34260	negative regulation of GTPase activity	P	Any process that stops or reduces the rate of GTP hydrolysis by a GTPase.
34263	autophagy in response to ER overload	P	The process in which cells digest parts of their own cytoplasm in response to the accumulation of misfolded proteins in the endoplasmic reticulum.
34264	isopentenyl adenine metabolic process	P	The chemical reactions and pathways involving the cytokinin 6-isopentenyladenine.
34265	isopentenyl adenine biosynthetic process	P	The chemical reactions and pathways resulting in the formation of the cytokinin 6-isopentenyladenine.
34266	isopentenyl adenine catabolic process	P	The chemical reactions and pathways resulting in the breakdown of the cytokinin 6-isopentenyladenine.
34267	discadenine metabolic process	P	The chemical reactions and pathways involving discadenine, (2S)-2-amino-4-{6-[(3-methylbut-2-en-1-yl)amino]-3H-purin-3-yl}butanoic acid.
34268	discadenine biosynthetic process	P	The chemical reactions and pathways resulting in the formation of discadenine, (2S)-2-amino-4-{6-[(3-methylbut-2-en-1-yl)amino]-3H-purin-3-yl}butanoic acid.
34269	discadenine catabolic process	P	The chemical reactions and pathways resulting in the breakdown of discadenine, (2S)-2-amino-4-{6-[(3-methylbut-2-en-1-yl)amino]-3H-purin-3-yl}butanoic acid.
34270	CVT complex	C	A protein complex that is involved in the CVT pathway. In budding yeast, the CVT complex consists of multimers of preApe1p.
34271	phosphatidylinositol 3-kinase complex, class III, type I	C	A class III phosphatidylinositol 3-kinase complex that is involved in autophagy. In budding yeast, this complex consists of Vps30p, Vps34p, Apg14p and Vps15p.
34272	phosphatidylinositol 3-kinase complex, class III, type II	C	A class III phosphatidylinositol 3-kinase complex that is involved in vacuolar protein sorting (VPS) via endosomes. In budding yeast, this complex consists of Vps30p, Vps34p, Vps38 and Vps15p.
34274	Atg12-Atg5-Atg16 complex	C	A protein complex required for the expansion of the autophagosomal membrane. In budding yeast, this complex consists of Atg12p, Atg5p and Atg16p.
34275	kynurenic acid metabolic process	P	The chemical reactions and pathways involving kynurenic acid, 4-hydroxyquinoline-2-carboxylic acid.
34276	kynurenic acid biosynthetic process	P	The chemical reactions and pathways resulting in the formation of kynurenic acid, 4-hydroxyquinoline-2-carboxylic acid.
34277	ent-cassa-12,15-diene synthase activity	F	Catalysis of the reaction: ent-copalyl diphosphate = ent-cassa-12,15-diene + diphosphate.
34278	stemar-13-ene synthase activity	F	Catalysis of the reaction: 9-alpha-copalyl diphosphate = stemar-13-ene + diphosphate.
34279	syn-pimara-7,15-diene synthase activity	F	Catalysis of the reaction: 9-alpha-copalyl diphosphate = 9-beta-pimara-7,15-diene + diphosphate.
34280	ent-sandaracopimaradiene synthase activity	F	Catalysis of the reaction: ent-copalyl diphosphate = ent-sandaracopimara-8(14),15-diene + diphosphate.
34281	ent-isokaurene synthase activity	F	Catalysis of the reaction: ent-copalyl diphosphate = ent-isokaurene + diphosphate.
34282	ent-pimara-8(14),15-diene synthase activity	F	Catalysis of the reaction: ent-copalyl diphosphate = ent-pimara-8(14),15-diene + diphosphate.
34283	syn-stemod-13(17)-ene synthase activity	F	Catalysis of the reaction: 9-alpha-copalyl diphosphate = stemod-13(17)-ene + diphosphate.
34284	response to monosaccharide	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a monosaccharide stimulus.
34285	response to disaccharide	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disaccharide stimulus.
34286	response to maltose	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a maltose stimulus.
34287	detection of monosaccharide stimulus	P	The series of events in which a stimulus from a monosaccharide is received and converted into a molecular signal.
34288	detection of disaccharide stimulus	P	The series of events in which a stimulus from a disaccharide is received and converted into a molecular signal.
34289	detection of maltose stimulus	P	The series of events in which a maltose stimulus is received by a cell and converted into a molecular signal.
34290	holin activity	F	A compound function consisting of the regulated formation of a pore via oligomerisation of an existing pool of subunits in the plasma membrane. The resulting channel activity directly or indirectly allows murein hydrolyases to access their cell wall substrate.
34291	canonical holin activity	F	A compound function consisting of the regulated formation of a pore via oligomerisation of an existing pool of subunits in the plasma membrane. The resulting channel activity directly allows release of a fully-folded phage-encoded endolysin (murein-degradase) from the cell.
34292	pinholin activity	F	A compound function consisting of the regulated formation of a pore via oligomerisation of an existing pool of subunits in the plasma membrane. The resulting ion channel activity indirectly allows endolysin (murein hydrolyases) to access their cell wall substrate by collapsing the proton motive force (PMF) across the membrane, allowing the endolysin to fold to an active form and hydrolyze bonds in the peptidoglycan cell wall.
34293	sexual sporulation	P	The formation of spores derived from the products of meiosis.
34294	sexual spore wall assembly	P	The aggregation, arrangement and bonding together of a set of components to form a sexual spore wall, the specialized envelope lying outside the cell membrane of a spore derived from a product of meiosis.
34295	basidiospore formation	P	The process in which spores form outside a specialized end cell known as a basidium. Basidia are characteristic of the basidiomycete fungi (phylum Basidiomycota), and give rise to spores that each contain a haploid nucleus that is the product of meiosis. The spores are usually attached to the basidium by short spikes called sterigmata (singular: sterigma). In most basidiomycetes there are four sterigmata (and four spores) to a basidium.
34296	zygospore formation	P	The process in which zygospores are formed. Zygospores are characteristic of the zygomycete fungi (phylum Zygomycota) thick-walled and darkly colored, and usually heavily ornamented as well, with many spines or ridges. It is formed between two specialized organs called suspensors, which are themselves usually heavily ornamented, one from each mating partner. The zygospore forms between them and then breaks away.
34297	oidium formation	P	The process in which oidia, a type of asexual spore found in fungi, are formed. Oidia are borne a few at a time on very simple hyphae that protrude a short distance into the substrate, and are usually presumed not to constitute the main reproductive strategy of the fungus.
34298	arthrospore formation	P	The formation of conidia by the conversion of a pre-existing hypha. An arthrospore is produced by the last cell on a hypha breaking off and dispersing. Usually the walls thicken and the cell(s) separates before swelling of each spore. Sometimes further septa form in each cell prior to disarticulation.
34299	reproductive blastospore formation	P	The formation of a spore following the marked enlargement of part of a cell before separation by a septum. Blastospores are a type of asexual spore found in some fungi, most notably the class Glomeromycota.
34300	sporangiospore formation	P	The process in which sporangiospores, a type of asexual spore found in fungi, are formed. Sporangiospores are formed within sac-like structure, the sporangium, following the division of the cytoplasm.
34301	endospore formation	P	The process in which a cell gives rise to an endospore, a dormant, highly resistant spore with a thick wall that forms within the mother cell. Endospores are produced by some low G+C Gram-positive bacteria in response to harsh conditions.
34302	akinete formation	P	The process in which an akinete, a thick-walled (encysted) dormant cell derived from the enlargement of a vegetative cell, is formed. Akinetes typically have granular cytoplasm, are more resistant to environmental extremes than vegetative cells, and are characteristic of several groups of Cyanobacteria.
34303	myxospore formation	P	The process in which differentiated, resting cells are formed, usually within a fruiting body by Myxobacteria. The myxospore is more resistant to high temperature, dessication, and UV than vegetative myxobacteria.
34304	actinomycete-type spore formation	P	The process in which differentiated, resting cells are formed from a substrate mycelium; characteristic of many members of the order Actinomycetales.
34305	regulation of asexual sporulation	P	Any process that modulates the frequency, rate or extent of spore formation from the products of mitosis.
34306	regulation of sexual sporulation	P	Any process that modulates the frequency, rate or extent of spore formation from the products of meiosis. An example of this is found in Saccharomyces cerevisiae.
34307	regulation of ascospore formation	P	Any process that modulates the frequency, rate or extent of ascospore formation. An example of this process is found in Saccharomyces cerevisiae.
34308	primary alcohol metabolic process	P	The chemical reactions and pathways involving primary alcohols. A primary alcohol is any alcohol in which a hydroxy group, -OH, is attached to a saturated carbon atom which has either three hydrogen atoms attached to it or only one other carbon atom and two hydrogen atoms attached to it.
34309	primary alcohol biosynthetic process	P	The chemical reactions and pathways resulting in the formation of primary alcohols. A primary alcohol is any alcohol in which a hydroxy group, -OH, is attached to a saturated carbon atom which has either three hydrogen atoms attached to it or only one other carbon atom and two hydrogen atoms attached to it.
34310	primary alcohol catabolic process	P	The chemical reactions and pathways resulting in the breakdown of primary alcohols. A primary alcohol is any alcohol in which a hydroxy group, -OH, is attached to a saturated carbon atom which has either three hydrogen atoms attached to it or only one other carbon atom and two hydrogen atoms attached to it.
34311	diol metabolic process	P	The chemical reactions and pathways involving a diol, a compound that contains two hydroxy groups, generally assumed to be, but not necessarily, alcoholic.
34312	diol biosynthetic process	P	The chemical reactions and pathways resulting in the formation of a diol, any alcohol containing two hydroxyl groups attached to saturated carbon atoms.
34313	diol catabolic process	P	The chemical reactions and pathways resulting in the breakdown of a diol, any alcohol containing two hydroxyl groups attached to saturated carbon atoms.
34314	Arp2/3 complex-mediated actin nucleation	P	The actin nucleation process in which actin monomers combine to form a new branch on the side of an existing actin filament; mediated by the Arp2/3 protein complex and its interaction with other proteins.
34315	regulation of Arp2/3 complex-mediated actin nucleation	P	Any process that modulates the frequency, rate or extent of actin nucleation mediated by the Arp2/3 complex and interacting proteins.
34316	negative regulation of Arp2/3 complex-mediated actin nucleation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of actin nucleation mediated by the Arp2/3 complex and interacting proteins.
34317	nicotinic acid riboside kinase activity	F	Catalysis of the reaction: ATP + nicotinic acid riboside = ADP + nicotinic acid mononucleotide.
34318	alcohol O-acyltransferase activity	F	Catalysis of the transfer of an acyl group to an oxygen atom on an alcohol acceptor molecule.
34319	alcohol O-butanoyltransferase activity	F	Catalysis of the reaction: butanoyl-CoA + an alcohol = CoA + a butyl ester.
34320	alcohol O-hexanoyltransferase activity	F	Catalysis of the reaction: hexanoyl-CoA + an alcohol = CoA + a hexyl ester.
34321	alcohol O-octanoyltransferase activity	F	Catalysis of the reaction: octanoyl-CoA + an alcohol = CoA + an octyl ester.
34322	alcohol O-decanoyltransferase activity	F	Catalysis of the reaction: decanoyl-CoA + an alcohol = CoA + a decyl ester.
34323	O-butanoyltransferase activity	F	Catalysis of the transfer of a butyl group to an oxygen atom on the acceptor molecule.
34324	O-hexanoyltransferase activity	F	Catalysis of the transfer of a hexyl group to an oxygen atom on the acceptor molecule.
34325	O-decanoyltransferase activity	F	Catalysis of the transfer of a decyl group to an oxygen atom on the acceptor molecule.
34326	butanoyltransferase activity	F	Catalysis of the transfer of a butanoyl (CH3-[CH2]2-CO-) group to an acceptor molecule.
34327	hexanoyltransferase activity	F	Catalysis of the transfer of a hexanoyl (CH3-[CH2]4-CO-) group to an acceptor molecule.
34328	decanoyltransferase activity	F	Catalysis of the transfer of a decanoyl (CH3-[CH2]8-CO-) group to an acceptor molecule.
34329	cell junction assembly	P	A cellular process that results in the aggregation, arrangement and bonding together of a set of components to form a cell junction.
34330	cell junction organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cell junction. A cell junction is a specialized region of connection between two cells or between a cell and the extracellular matrix.
34331	cell junction maintenance	P	The organization process that preserves a cell junction in a stable functional or structural state. A cell junction is a specialized region of connection between two cells or between a cell and the extracellular matrix.
34332	adherens junction organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an adherens junction. An adherens junction is a cell junction at which the cytoplasmic face of the plasma membrane is attached to actin filaments.
34333	adherens junction assembly	P	The aggregation, arrangement and bonding together of a set of components to form an adherens junction. An adherens junction is a cell junction at which the cytoplasmic face of the plasma membrane is attached to actin filaments.
34334	adherens junction maintenance	P	The maintenance of an adherens junction. An adherens junction is a cell junction at which the cytoplasmic face of the plasma membrane is attached to actin filaments.
34335	DNA supercoiling activity	F	Catalytic introduction of supercoils in a DNA molecule or region thereof. In bacteria, negative supercoils are only introduced by DNA gyrase, a type II topoisomerase, but not all DNA gyrases are capable of introducing supercoils. In bacteria, the level of supercoiling varies widely between species and has been characterized properly in only a handful of organisms. The best characterized enzyme, from E.coli, is exceptionally proficient at supercoiling and this ability is not representative of all bacteria.
34336	misfolded RNA binding	F	Interacting selectively and non-covalently with an RNA molecule that has assumed an incorrect conformation.
34337	RNA folding	P	The process of assisting in the covalent and noncovalent assembly of single or multimeric RNAs into the correct tertiary structure.
34338	short-chain carboxylesterase activity	F	Catalysis of the reaction: a carboxylic ester + H2O = an alcohol + a carboxylic anion, where the carboxylic chain has 8 or fewer carbon atoms.
34340	response to type I interferon	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a type I interferon stimulus. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families.
34341	response to interferon-gamma	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-gamma stimulus. Interferon-gamma is also known as type II interferon.
34342	response to type III interferon	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a type III interferon stimulus. Interferon lambda is the only member of the type III interferon found so far.
34343	type III interferon production	P	The appearance of type III interferon due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Interferon lambda is the only member of the type III interferon found so far.
34344	regulation of type III interferon production	P	Any process that modulates the frequency, rate, or extent of type III interferon production. Interferon lambda is the only member of the type III interferon found so far.
34345	negative regulation of type III interferon production	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of type III interferon production. Interferon lambda is the only member of the type III interferon found so far.
34346	positive regulation of type III interferon production	P	Any process that activates or increases the frequency, rate, or extent of type III interferon production. Interferon lambda is the only member of the type III interferon found so far.
34347	type III interferon binding	F	Interacting selectively and non-covalently with a type III interferon. Interferon lambda is the only member of the type III interferon found so far.
34348	type III interferon receptor activity	F	Combining with a type III interferon and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. Interferon lambda is the only member of the type III interferon found so far.
34349	glial cell apoptotic process	P	Any apoptotic process in a glial cell, a non-neuronal cell of the nervous system.
34350	regulation of glial cell apoptotic process	P	Any process that modulates the frequency, rate, or extent of glial cell apoptotic process.
34351	negative regulation of glial cell apoptotic process	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of glial cell apoptotic process.
34352	positive regulation of glial cell apoptotic process	P	Any process that activates or increases the frequency, rate, or extent of glial cell apoptotic process.
34353	RNA pyrophosphohydrolase activity	F	Catalysis of the removal of a 5' terminal pyrophosphate from the 5'-triphosphate end of an RNA, leaving a 5'-monophosphate end.
34354	'de novo' NAD biosynthetic process from tryptophan	P	The chemical reactions and pathways resulting in the formation of nicotinamide adenine dinucleotide (NAD), beginning with the synthesis of tryptophan from simpler precursors; biosynthesis may be of either the oxidized form, NAD, or the reduced form, NADH.
34355	NAD salvage	P	Any process that generates nicotinamide adenine dinucleotide (NAD) from derivatives of it, without de novo synthesis; salvage is usually from the degradation products nicotinic acid (Na) and nicotinamide (Nam).
34356	NAD biosynthesis via nicotinamide riboside salvage pathway	P	The chemical reactions and pathways resulting in the formation of nicotinamide adenine dinucleotide (NAD) from the vitamin precursor nicotinamide riboside.
34357	photosynthetic membrane	C	A membrane enriched in complexes formed of reaction centers, accessory pigments and electron carriers, in which photosynthetic reactions take place.
34358	plasma lipoprotein particle	C	A spherical particle with a hydrophobic core of triglycerides and/or cholesterol esters, surrounded by an amphipathic monolayer of phospholipids, cholesterol and apolipoproteins. Plasma lipoprotein particles transport lipids, which are non-covalently associated with the particles, in the blood or lymph.
34359	mature chylomicron	C	A chylomicron that contains apolipoprotein C2 (APOC2), a cofactor for lipoprotein lipase (LPL) activity, and has a mean diameter of 500 nm and density of 0.95g/ml. Mature chylomicron particles transport exogenous (dietary) lipids from the intestines to other body tissues, via the blood and lymph.
34360	chylomicron remnant	C	A lipoprotein particle that is derived from a mature chylomicron particle by the removal of triglycerides from the chylomicron core by lipoprotein lipase and the subsequent loss of surface components. It characteristically contains apolipoprotein E (APOE) and is cleared from the blood by the liver.
34361	very-low-density lipoprotein particle	C	A triglyceride-rich lipoprotein particle that is typically composed of APOB100, APOE and APOCs and has a density of about 1.006 g/ml and a diameter of between 20-80 nm. It is found in blood and transports endogenous products (newly synthesized cholesterol and triglycerides) from the liver.
34362	low-density lipoprotein particle	C	A lipoprotein particle, rich in cholesterol esters and low in triglycerides that is typically composed of APOB100 and APOE and has a density of 1.02-1.06 g/ml and a diameter of between 20-25 nm. LDL particles are formed from VLDL particles (via IDL) by the loss of triglyceride and gain of cholesterol ester. They transport endogenous cholesterol (and to some extent triglycerides) from peripheral tissues back to the liver.
34363	intermediate-density lipoprotein particle	C	A triglyceride-rich lipoprotein particle that typically contains APOB100, APOE and APOCs and has a density of 1.006-1.019 g/ml and a diameter of between 25-30 nm. IDL particles are found in blood and are formed by the delipidation of very-low-density lipoprotein particles (VLDL). IDL particles are removed from blood by the liver, following binding to the APOE receptor, or are converted to low-density lipoprotein (LDL).
34364	high-density lipoprotein particle	C	A lipoprotein particle with a high density (typically 1.063-1.21 g/ml) and a diameter of 5-10 nm that contains APOAs and may contain APOCs and APOE; found in blood and carries lipids from body tissues to the liver as part of the reverse cholesterol transport process.
34365	discoidal high-density lipoprotein particle	C	A newly formed high-density lipoprotein particle; consists of a phospholipid bilayer surrounded by two or more APOA1 molecules. The discoidal HDL particle is formed when lipid-free or lipid-poor APOA1 acquires phospholipids and unesterified cholesterol from either cell membranes or triglyceride-rich lipoproteins (undergoing lipolysis by lipoprotein lipase).
34366	spherical high-density lipoprotein particle	C	A mature high-density lipoprotein (HDL) particle, converted from discoidal HDL particles following the esterification of cholesterol in the particle by phosphatidylcholine-sterol O-acyltransferase (lecithin cholesterol acyltransferase; LCAT).
34367	macromolecular complex remodeling	P	The acquisition, loss, or modification of macromolecules within a complex, resulting in the alteration of an existing complex.
34368	protein-lipid complex remodeling	P	The acquisition, loss or modification of a protein or lipid within a protein-lipid complex.
34369	plasma lipoprotein particle remodeling	P	The acquisition, loss or modification of a protein or lipid within a plasma lipoprotein particle, including the hydrolysis of triglyceride by hepatic lipase, with the subsequent loss of free fatty acid, and the esterification of cholesterol by phosphatidylcholine-sterol O-acyltransferase (lecithin cholesterol acyltransferase; LCAT).
34370	triglyceride-rich lipoprotein particle remodeling	P	The acquisition, loss or modification of a protein or lipid within a triglyceride-rich lipoprotein particle, including the hydrolysis of triglyceride by lipoprotein lipase, with the subsequent loss of free fatty acid, and the transfer of cholesterol esters to a triglyceride-rich lipoprotein particle by cholesteryl ester transfer protein (CETP), with the simultaneous transfer of triglyceride from a triglyceride-rich lipoprotein particle.
34371	chylomicron remodeling	P	The acquisition, loss or modification of a protein or lipid within a chylomicron, including the hydrolysis of triglyceride by lipoprotein lipase and the subsequent loss of free fatty acid.
34372	very-low-density lipoprotein particle remodeling	P	The acquisition, loss or modification of a protein or lipid within a very-low-density lipoprotein particle, including the hydrolysis of triglyceride by hepatic lipase or lipoprotein lipase and the subsequent loss of free fatty acid.
34373	intermediate-density lipoprotein particle remodeling	P	The acquisition, loss or modification of a protein or lipid within an intermediate-density lipoprotein particle.
34374	low-density lipoprotein particle remodeling	P	The acquisition, loss or modification of a protein or lipid within a low-density lipoprotein particle, including the hydrolysis of triglyceride by hepatic lipase, with the subsequent loss of free fatty acid, and the transfer of cholesterol esters from LDL to a triglyceride-rich lipoprotein particle by cholesteryl ester transfer protein (CETP), with the simultaneous transfer of triglyceride to LDL.
34375	high-density lipoprotein particle remodeling	P	The acquisition, loss or modification of a protein or lipid within a high-density lipoprotein particle, including the hydrolysis of triglyceride by hepatic lipase, with the subsequent loss of free fatty acid, and the transfer of cholesterol esters from LDL to a triglyceride-rich lipoprotein particle by cholesteryl ester transfer protein (CETP), with the simultaneous transfer of triglyceride to LDL.
34376	conversion of discoidal high-density lipoprotein particle to spherical high-density lipoprotein particle	P	The process in which a discoidal high-density lipoprotein (HDL) particle acquires additional lipid or protein molecules, and cholesterol in the particle is converted to tightly bound cholesterol esters by the action of phosphatidylcholine-sterol O-acyltransferase (lecithin cholesterol acyltransferase; LCAT), resulting in the formation of a spherical HDL particle.
34377	plasma lipoprotein particle assembly	P	The aggregation and arrangement of proteins and lipids to form a plasma lipoprotein particle.
34378	chylomicron assembly	P	The aggregation and arrangement of proteins and lipids in the intestine to form a chylomicron.
34379	very-low-density lipoprotein particle assembly	P	The aggregation and arrangement of proteins and lipids in the liver to form a very-low-density lipoprotein particle.
34380	high-density lipoprotein particle assembly	P	The aggregation and arrangement of proteins and lipids to form a high-density lipoprotein particle.
34381	plasma lipoprotein particle clearance	P	The process in which a lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.
34382	chylomicron remnant clearance	P	The process in which a chylomicron remnant is removed from the blood via receptor-mediated endocytosis into liver cells and its constituent parts degraded.
34383	low-density lipoprotein particle clearance	P	The process in which a low-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.
34384	high-density lipoprotein particle clearance	P	The process in which a high-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.
34385	triglyceride-rich lipoprotein particle	C	A plasma lipoprotein particle that has a hydrophobic core enriched in triglycerides surrounded by an amphipathic monolayer of phospholipids, cholesterol and apolipoproteins. Triglyceride-rich lipoproteinparticles transport lipids, which are non-covalently associated with the particles, in the blood.
34386	4-aminobutyrate:2-oxoglutarate transaminase activity	F	Catalysis of the reaction: 4-aminobutanoate + 2-oxoglutarate = succinate semialdehyde + L-glutamate.
34387	4-aminobutyrate:pyruvate transaminase activity	F	Catalysis of the reaction: 4-aminobutanoate + pyruvate = succinate semialdehyde + alanine.
34388	Pwp2p-containing subcomplex of 90S preribosome	C	A protein complex that forms a subcomplex of the 90S preribosome and can interact directly with the 5' External Transcribed Spacer (ETS) of the full length pre-rRNA transcript. In S. cerevisiae, it sediments at 25-30 S and is composed of Pwp2p, Dip2p, Utp21p, Utp13p, Utp18p, and Utp6p.
34389	lipid particle organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lipid particle.
34390	smooth muscle cell apoptotic process	P	Any apoptotic process in a smooth muscle cell. Smooth muscle consists of non-striated, elongated, spindle-shaped cell found lining the digestive tract, uterus, and blood vessels.
34391	regulation of smooth muscle cell apoptotic process	P	Any process that modulates the frequency, rate, or extent of smooth muscle cell apoptotic process.
34392	negative regulation of smooth muscle cell apoptotic process	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of smooth muscle cell apoptotic process.
34393	positive regulation of smooth muscle cell apoptotic process	P	Any process that activates or increases the frequency, rate, or extent of smooth muscle cell apoptotic process.
34394	protein localization to cell surface	P	A process in which a protein is transported to, or maintained in, a location within the external part of the cell wall and/or plasma membrane.
34395	regulation of transcription from RNA polymerase II promoter in response to iron	P	Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter in response to an iron stimulus.
34396	negative regulation of transcription from RNA polymerase II promoter in response to iron	P	Any process that stops, prevents or reduces the rate of transcription from an RNA polymerase II promoter in response to an iron stimulus.
34397	telomere localization	P	Any process in which a telomere is transported to, and/or maintained in, a specific location.
34398	telomere tethering at nuclear periphery	P	The process in which a telomere is maintained in a specific location at the nuclear periphery.
34399	nuclear periphery	C	The portion of the nuclear lumen proximal to the inner nuclear membrane.
34400	gerontoplast	C	A plastid found in senescing, formerly green tissues that is derived from a chloroplast that undergoes an organized developmental program of senescence.
34401	chromatin organization involved in regulation of transcription	P	Any cellular process that results in the specification, formation or maintenance of the physical structure of eukaryotic chromatin that modulates the rate, frequency or extent of DNA-dependent transcription.
34402	recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex	P	The process in which proteins required for 3'-end transcript processing become associated with the RNA polymerase II holoenzyme complex and the 3' end of a transcript.
34403	alignment of 3' and 5' splice sites of mRNA	P	Recognition of both the 5' and 3'-splice sites and positioning them in the correct alignment with respect to each other so that the second catalytic step of nuclear mRNA splicing can occur.
34404	nucleobase-containing small molecule biosynthetic process	P	The chemical reactions and pathways resulting in the formation of a nucleobase-containing small molecule: a nucleobase, a nucleoside, or a nucleotide.
34405	response to fluid shear stress	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fluid shear stress stimulus. Fluid shear stress is the force acting on an object in a system where the fluid is moving across a solid surface.
34406	cell wall beta-glucan metabolic process	P	The chemical reactions and pathways involving beta-glucans, compounds composed of glucose residues linked by beta-D-glucosidic bonds, found in the walls of cells.
34407	cell wall (1->3)-beta-D-glucan metabolic process	P	The chemical reactions and pathways involving (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D-glucosidic bonds, found in the walls of cells.
34408	ascospore wall beta-glucan metabolic process	P	The chemical reactions and pathways involving beta-glucans, compounds composed of glucose residues linked by beta-D-glucosidic bonds, found in the walls of ascospores.
34409	ascospore wall (1->3)-beta-D-glucan metabolic process	P	The chemical reactions and pathways involving (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D-glucosidic bonds, found in the walls of ascospores.
34410	cell wall beta-glucan biosynthetic process	P	The chemical reactions and pathways resulting in the formation of beta-glucans, compounds composed of glucose residues linked by beta-D-glucosidic bonds, found in the walls of cells.
34411	cell wall (1->3)-beta-D-glucan biosynthetic process	P	The chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D-glucosidic bonds, found in the walls of cells.
34412	ascospore wall beta-glucan biosynthetic process	P	The chemical reactions and pathways resulting in the formation of beta-glucans, compounds composed of glucose residues linked by beta-D-glucosidic bonds, found in the walls of ascospores.
34413	ascospore wall (1->3)-beta-D-glucan biosynthetic process	P	The chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D-glucosidic bonds, found in the walls of ascospores.
34414	tRNA 3'-trailer cleavage, endonucleolytic	P	Endonucleolytic cleavage of the 3'-end of the pre-tRNA as part of the process of generating the mature 3'-end of the tRNA.
34415	tRNA 3'-trailer cleavage, exonucleolytic	P	Exonucleolytic cleavage of the 3'-end of the pre-tRNA as part of the process of generating the mature 3'-end of the tRNA.
34416	bisphosphoglycerate phosphatase activity	F	Catalysis of the reaction: 2,3-diphosphoglycerate + H2O = phosphoglycerate + phosphate.
34417	bisphosphoglycerate 3-phosphatase activity	F	Catalysis of the reaction: 2,3-diphosphoglycerate + H2O = 2-phospho-D-glycerate + phosphate.
34418	urate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of urate, the anion of uric acid, 2,6,8-trioxypurine.
34419	L-2-hydroxyglutarate oxidase activity	F	Catalysis of the reaction: L-2-hydroxyglutarate + O2 = 2-oxoglutarate + hydrogen peroxide.
34420	co-translational protein acetylation	P	The addition of an acetyl group to one or more amino acids in a protein, occurring before the protein has been completely translated and released from the ribosome.
34421	post-translational protein acetylation	P	The addition of an acetyl group to one or more amino acids in a protein, occurring after the protein has been completely translated and released from the ribosome.
34422	aleurone grain lumen	C	The volume enclosed by the membrane of an aleurone grain.
34423	autophagosome lumen	C	The volume enclosed within the autophagosome double-membrane.
34424	Vps55/Vps68 complex	C	A membrane-associated protein complex that is required for a late stage of endosomal transport. In budding yeast, this complex consists of Vps55p and Vps68p proteins.
34425	etioplast envelope	C	The double lipid bilayer enclosing the etioplast and separating its contents from the rest of the cytoplasm; includes the intermembrane space.
34426	etioplast membrane	C	Either of the lipid bilayers that surround a etioplast and form the etioplast envelope.
34427	nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'	P	The chemical reactions and pathways resulting in the breakdown of the mRNA transcript body that occurs when the 3' end is not protected by a 3'-poly(A) tail; degradation proceeds in the 3' to 5' direction.
34428	nuclear-transcribed mRNA catabolic process, exonucleolytic, 5'-3'	P	The chemical reactions and pathways resulting in the breakdown of the mRNA transcript body that occurs when the 5' end is not protected by a 5'-cap; degradation proceeds in the 5' to 3' direction.
34429	tectobulbar tract morphogenesis	P	Generation of a long process of a CNS neuron, that carries efferent (outgoing) action potentials from the cell body in the optic tectum towards target cells in the premotor reticulospinal system in the hindbrain.
34430	monolayer-surrounded lipid storage body outer lipid monolayer	C	The single layer of phopholipids surrounding a lipid storage body.
34431	bis(5'-adenosyl)-hexaphosphatase activity	F	Catalysis of the reaction: P1-P6-bis(5'-adenosyl) hexaphosphate + H2O = AMP + adenosine 5'-pentaphosphate.
34432	bis(5'-adenosyl)-pentaphosphatase activity	F	Catalysis of the reaction: P1-P6-bis(5'-adenosyl) pentaphosphate + H2O = AMP + adenosine 5'-tetraphosphate.
34433	steroid esterification	P	A lipid modification process in which a steroid ester is formed by the combination of a carboxylic acid (often a fatty acid) and a steroid molecule (e.g. cholesterol).
34434	sterol esterification	P	A lipid modification process in which a sterol ester is formed by the combination of a carboxylic acid (often a fatty acid) and a sterol molecule (e.g. cholesterol).
34435	cholesterol esterification	P	A lipid modification process in which a sterol ester is formed by the combination of a carboxylic acid (often a fatty acid) and cholesterol. In the blood this process is associated with the conversion of free cholesterol into cholesteryl ester, which is then sequestered into the core of a lipoprotein particle.
34436	glycoprotein transport	P	The directed movement of a glycoprotein, any protein that contains covalently bound glycose (i.e. monosaccharide) residues, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
34437	glycoprotein transporter activity	F	Enables the directed movement of a glycoprotein, any protein that contains covalently bound glycose (i.e. monosaccharide) residues, into, out of or within a cell, or between cells.
34438	lipoprotein amino acid oxidation	P	The modification of a lipoprotein by oxidation of one or more amino acids in the protein.
34439	lipoprotein lipid oxidation	P	The modification of a lipoprotein by oxidation of the lipid group.
34440	lipid oxidation	P	The removal of one or more electrons from a lipid, with or without the concomitant removal of a proton or protons, by reaction with an electron-accepting substance, by addition of oxygen or by removal of hydrogen.
34441	plasma lipoprotein particle oxidation	P	The modification of a lipoprotein by oxidation of one or more amino acids or the lipid group, occurring in the blood plasma.
34442	regulation of lipoprotein oxidation	P	Any process that modulates the frequency, rate or extent of lipoprotein oxidation.
34443	negative regulation of lipoprotein oxidation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of lipoprotein oxidation.
34444	regulation of plasma lipoprotein particle oxidation	P	Any process that modulates the frequency, rate or extent of lipoprotein oxidation, occurring in the blood plasma.
34445	negative regulation of plasma lipoprotein particle oxidation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of lipoprotein particle oxidation, occurring in the blood plasma.
34446	substrate adhesion-dependent cell spreading	P	The morphogenetic process that results in flattening of a cell as a consequence of its adhesion to a substrate.
34447	very-low-density lipoprotein particle clearance	P	The process in which a very-low-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.
34448	EGO complex	C	A vacuolar membrane-associated protein complex that is required for activation of microautophagy during exit from rapamycin-induced growth arrest. In budding yeast, S. cerevisiae, this complex includes Gtr1p, Gtr2p, Meh1p, and Slm4p.
34450	ubiquitin-ubiquitin ligase activity	F	Isoenergetic transfer of ubiquitin from one protein to an existing ubiquitin chain via the reaction X-ubiquitin + Y-ubiquitin -> Y-ubiquitin-ubiquitin + X, where both the X-ubiquitin and Y-ubiquitin-ubiquitin linkages are thioester bonds between the C-terminal glycine of ubiquitin and a sulfhydryl side group of a cysteine residue.
34451	centriolar satellite	C	A small (70-100 nm) cytoplasmic granule that contains a number of centrosomal proteins; centriolar satellites traffic toward microtubule minus ends and are enriched near the centrosome.
34452	dynactin binding	F	Interacting selectively and non-covalently with any part of a dynactin complex; dynactin is a large protein complex that activates dynein-based motor activity.
34453	microtubule anchoring	P	Any process in which a microtubule is maintained in a specific location in a cell.
34454	microtubule anchoring at centrosome	P	Any process in which a microtubule is maintained in a specific location in a cell by attachment to a centrosome.
34455	t-UTP complex	C	A protein complex that forms a subcomplex of the 90S preribosome and is required for the subsequent assembly of the rest of the preribosome. In S. cerevisiae, it is composed of Utp5p, Utp4p, Nan1p, Utp8p, Utp9p, Utp10 and Utp15p.
34456	UTP-C complex	C	A protein complex that forms a subcomplex of the 90S preribosome. In S. cerevisiae, it is composed of Rrp7p, Utp22p, Ckb1p, Cka1p, Ckb2p and Cka2p.
34457	Mpp10 complex	C	A protein complex that forms a subcomplex of the 90S preribosome. In S. cerevisiae, it is composed of Mpp10p, Imp3p and Imp4p.
34458	3'-5' RNA helicase activity	F	Catalysis of the unwinding of an RNA helix in the direction 3' to 5'.
34459	ATP-dependent 3'-5' RNA helicase activity	F	Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction drives the unwinding of an RNA helix in the direction 3' to 5'.
34460	uropod assembly	P	The assembly of a uropod by rearrangement of the cytoskeleton and overlying membrane.
34461	uropod retraction	P	The process in which a uropod detaches from the cell substrate and retracts the rear of a migrating cell.
34462	small-subunit processome assembly	P	The aggregation, arrangement and bonding together of proteins and RNA molecules to form a small-subunit processome.
34463	90S preribosome assembly	P	The aggregation, arrangement and bonding together of proteins and RNA molecules to form a 90S preribosome. The 90S preribosome represents the complex that forms on the primary rRNA transcript before it splits into the small subunit and large subunit portions.
34464	BBSome	C	A ciliary protein complex involved in cilium biogenesis. It consists of at least seven Bardet-Biedl syndrome (BBS) proteins and BBIP10. It moves in association with IFT trains through cilia (likely as an IFT-A/B adaptor or cargo), and is required for the integrity of IFT-A and IFT-B.
34465	response to carbon monoxide	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbon monoxide (CO) stimulus.
34466	chromaffin granule lumen	C	The volume enclosed by the membrane of a chromaffin granule.
34467	esterosome lumen	C	The volume enclosed by the membrane of an esterosome.
34468	glycosome lumen	C	The volume enclosed by the membrane of a glycosome.
34469	Golgi stack lumen	C	The volume enclosed by any of the membranes of the thin, flattened cisternae that form the central portion of the Golgi complex.
34470	ncRNA processing	P	Any process that results in the conversion of one or more primary non-coding RNA (ncRNA) transcripts into one or more mature ncRNA molecules.
34471	ncRNA 5'-end processing	P	Any process involved in forming the mature 5' end of a non-coding RNA molecule.
34472	snRNA 3'-end processing	P	Any process involved in forming the mature 3' end of an snRNA molecule.
34473	U1 snRNA 3'-end processing	P	Any process involved in forming the mature 3' end of a U1 snRNA molecule.
34474	U2 snRNA 3'-end processing	P	Any process involved in forming the mature 3' end of a U2 snRNA molecule.
34475	U4 snRNA 3'-end processing	P	Any process involved in forming the mature 3' end of a U4 snRNA molecule.
34476	U5 snRNA 3'-end processing	P	Any process involved in forming the mature 3' end of a U5 snRNA molecule.
34477	U6 snRNA 3'-end processing	P	Any process involved in forming the mature 3' end of a U6 snRNA molecule.
34478	phosphatidylglycerol catabolic process	P	The chemical reactions and pathways resulting in the breakdown of phosphatidylglycerols, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of glycerol.
34479	phosphatidylglycerol phospholipase C activity	F	Catalysis of the reaction: a phosphatidylglycerol + H2O = 1,2-diacylglycerol + glycerol 3-phosphate.
34480	phosphatidylcholine phospholipase C activity	F	Catalysis of the reaction: phosphatidylcholine + H2O = 1,2-diacylglycerol + a choline phosphate.
34481	chondroitin sulfotransferase activity	F	Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + chondroitin = adenosine 3',5'-bisphosphate + chondroitin sulfate.
34482	chondroitin 2-O-sulfotransferase activity	F	Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + chondroitin = adenosine 3',5'-bisphosphate + chondroitin 2'-O-sulfate. Results in sulfation of glucuronic acid and iduronic acid residues.
34483	heparan sulfate sulfotransferase activity	F	Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + heparan sulfate = adenosine 3',5'-bisphosphate + sulfated heparan sulfate.
34484	raffinose catabolic process	P	The chemical reactions and pathways resulting in the breakdown of raffinose, the trisaccharide beta-D-fructofuranosyl alpha-D-galactopyranosyl-(1->6)-alpha-D-glucopyranoside.
34485	phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity	F	Catalysis of the reaction: phosphatidylinositol-3,4,5-trisphosphate + H2O = phosphatidylinositol-3,4-bisphosphate + phosphate.
34486	vacuolar transmembrane transport	P	The process in which a solute is transported from one side of the vacuolar membrane to the other.
34487	vacuolar amino acid transmembrane transport	P	The process in which an amino acid is transported from one side of the vacuolar membrane to the other.
34488	basic amino acid transmembrane export from vacuole	P	The directed movement of basic amino acids out of the vacuole, across the vacuolar membrane.
34489	neutral amino acid transmembrane export from vacuole	P	The directed movement of neutral amino acids out of the vacuole, across the vacuolar membrane.
34490	basic amino acid transmembrane import into vacuole	P	The directed movement of basic amino acids into the vacuole across the vacuolar membrane.
34491	neutral amino acid transmembrane import into vacuole	P	The directed movement of neutral amino acids into the vacuole across the vacuolar membrane.
34492	hydrogenosome lumen	C	The volume enclosed by the hydrogenosome membrane.
34493	melanosome lumen	C	The volume enclosed by the melanosome membrane.
34494	microneme lumen	C	The volume enclosed by the microneme membrane.
34495	protein storage vacuole lumen	C	The volume enclosed by the protein storage vacuole membrane.
34496	multivesicular body membrane disassembly	P	The controlled breakdown of the membranes of multivesicular bodies.
34497	protein localization to pre-autophagosomal structure	P	Any process in which a protein is transported to, or maintained at, the pre-autophagosomal structure (PAS).
34498	early endosome to Golgi transport	P	The directed movement of substances from early endosomes to the Golgi.
34499	late endosome to Golgi transport	P	The directed movement of substances from late endosomes to the Golgi.
34501	protein localization to kinetochore	P	Any process in which a protein is transported to, or maintained at, the kinetochore.
34502	protein localization to chromosome	P	Any process in which a protein is transported to, or maintained at, a specific location on a chromosome.
34503	protein localization to nucleolar rDNA repeats	P	Any process in which a protein is transported to, or maintained at, the rDNA repeats on a chromosome in the nucleolus.
34504	protein localization to nucleus	P	A process in which a protein is transported to, or maintained in, a location within the nucleus.
34505	tooth mineralization	P	The process in which calcium salts are deposited into calcareous tooth structures such as dental enamel, dentin and cementum.
34506	chromosome, centromeric core domain	C	The innermost portion of the centromeric region of a chromosome, encompassing the core region of a chromosome centromere and the proteins that bind to it.
34507	chromosome, centromeric outer repeat region	C	The portion of the centromeric region of a chromosome that flanks the core region, encompassing repeated regions of a chromosome centromere and the proteins that bind to it.
34508	centromere complex assembly	P	The aggregation, arrangement and bonding together of proteins and centromeric DNA molecules to form a centromeric protein-DNA complex. Includes the formation of the chromatin structures which form a platform for the kinetochore, and assembly of the kinetochore onto this specialized chromatin. In fission yeast and higher eukaryotes this process also includes the formation of heterochromatin at the outer repeat (pericentric) regions of the centromere.
34510	centromere separation	P	The cell cycle process in which centromeres are physically detached from each other during chromosome separation.
34511	U3 snoRNA binding	F	Interacting selectively and non-covalently with U3 small nucleolar RNA.
34512	box C/D snoRNA binding	F	Interacting selectively and non-covalently with box C/D small nucleolar RNA.
34513	box H/ACA snoRNA binding	F	Interacting selectively and non-covalently with box H/ACA small nucleolar RNA.
34514	mitochondrial unfolded protein response	P	The series of molecular signals generated as a consequence of the presence of unfolded proteins in the mitochondrial matrix; results in transcriptional upregulation of nuclear genes encoding mitochondrial stress proteins.
34515	proteasome storage granule	C	A multisubunit proteasome complex that localizes in the cytoplasm as dot-like structures when cells are in a quiescent state.
34516	response to vitamin B6	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin B6 stimulus. Vitamin B6 encompasses pyridoxal, pyridoxamine and pyridoxine and the active form, pyridoxal phosphate.
34517	ribophagy	P	The process in which cells degrade mature ribosomes under conditions of starvation.
34518	RNA cap binding complex	C	Any protein complex that binds to a specialized RNA cap structure at any time in the lifetime of the RNA.
34519	cytoplasmic RNA cap binding complex	C	A protein complex found in the cytoplasm that binds the 5' cap structure of an mRNA, and typically consists of the cap-binding protein eIF4E, the adaptor protein eIF4G, and a multi-factor complex comprising eIF1, eIF2, eIF3 and eIF5. This complex mediates recruitment of the 40S subunit to mRNA.
34520	2-naphthaldehyde dehydrogenase activity	F	Catalysis of the reaction: 2-naphthaldehyde + NAD+ + H2O = 2-naphthoate + NADH + H+.
34521	1-naphthoic acid dioxygenase activity	F	Catalysis of the reaction: 1-naphthoic acid + NADH + O2 + H+ = cis-1,2-dihydroxy-1,2-dihydro-8-carboxynaphthalene + NAD+.
34522	cis-1,2-dihydroxy-1,2-dihydro-8-carboxynaphthalene dehydrogenase activity	F	Catalysis of the reaction: cis-1,2-dihydroxy-1,2-dihydro-8-carboxynaphthalene = 1,2-dihydroxy-8-carboxynaphthalene + 2 H+ + 2 e-.
34523	3-formylsalicylate oxidase activity	F	Catalysis of the reaction: 3-formylsalicylic acid + O2 + H2O = 2-hydroxyisophthalic acid + hydrogen peroxide.
34524	2-hydroxyisophthalate decarboxylase activity	F	Catalysis of the reaction: 2-hydroxyisophthalic acid = salicylate + CO2.
34525	1-naphthaldehyde dehydrogenase activity	F	Catalysis of the reaction: 1-naphthaldehyde + NAD+ + H2O = 1-naphthoic acid + NADH + H+.
34526	2-methylnaphthalene hydroxylase activity	F	Catalysis of the reaction: 2-methylnaphthalene + NADH + O2 + H+ = 2-hydroxymethylnaphthalene + NAD+ + H2O.
34527	1,2-dihydroxy-8-carboxynaphthalene dioxygenase activity	F	Catalysis of the reaction: 1,2-dihydroxy-8-carboxynaphthalene + O2 = 2-carboxy-2-hydroxy-8-carboxychromene.
34528	2-carboxy-2-hydroxy-8-carboxychromene isomerase activity	F	Catalysis of the reaction: 2-carboxy-2-hydroxy-8-carboxychromene = 2-hydroxy-3-carboxybenzalpyruvate.
34529	2-hydroxy-3-carboxy-benzalpyruvate hydratase-aldolase activity	F	Catalysis of the reaction: 2-hydroxy-3-carboxybenzalpyruvate + H2O = 3-formylsalicylic acid + pyruvate.
34530	4-hydroxymethylsalicyaldehyde dehydrogenase activity	F	Catalysis of the reaction: 4-hydroxymethylsalicylaldehyde + NAD+ + H2O = 4-hydroxymethylsalicylate + NADH + 2 H+.
34531	2-hydroxy-4-hydroxymethylbenzalpyruvate hydratase-aldolase activity	F	Catalysis of the reaction: 2-hydroxy-4-hydroxymethylbenzalpyruvate + H2O = pyruvate + 4-hydroxymethylsalicylaldehyde.
34532	2-hydroxy-7-hydroxymethylchromene-2-carboxylate isomerase activity	F	Catalysis of the reaction: 2-hydroxy-7-hydroxymethylchromene-2-carboxylate = 2-hydroxy-4-hydroxymethylbenzalpyruvate.
34533	1,2-dihydroxy-7-hydroxymethylnaphthalene dioxygenase activity	F	Catalysis of the reaction: 1,2-dihydroxy-7-hydroxymethylnaphthalene + O2 = 2-hydroxy-7-hydroxymethylchromene-2-carboxylate.
34534	1-methylnaphthalene hydroxylase activity	F	Catalysis of the reaction: 1-methylnaphthalene + NADH + H+ + O2 = 1-hydroxymethylnaphthalene + NAD+ + H2O.
34535	1,2-dihydroxy-8-methylnaphthalene dioxygenase activity	F	Catalysis of the reaction: 1,2-dihydroxy-8-methylnaphthalene + O2 = 2-hydroxy-8-methylchromene-2-carboxylate + H+.
34536	2-hydroxy-8-methylchromene-2-carboxylate isomerase activity	F	Catalysis of the reaction: 2-hydroxy-8-methylchromene-2-carboxylate = 2-hydroxy-3-methylbenzalpyruvate.
34537	2-hydroxy-3-methylbenzalpyruvate hydratase-aldolase activity	F	Catalysis of the reaction: 2-hydroxy-3-methylbenzalpyruvate + H2O = pyruvate + 3-methylsalicylaldehyde.
34538	3-methylsalicylaldehyde dehydrogenase activity	F	Catalysis of the reaction: 3-methylsalicylaldehyde + NAD+ = 3-methylsalicylate + NADH + H+.
34539	3,3',5,5'-tetrabromobisphenol A reductive dehalogenase activity	F	Catalysis of the reaction: 3,3',5,5'-tetrabromobisphenol A + 2 H+ + 2 e- = 3,3',5-tribromobisphenol A + HBr.
34540	3-monobromobisphenol A reductive dehalogenase activity	F	Catalysis of the reaction: 3-monobromobisphenol A + 2 H+ + 2 e- = bisphenol A + HBr.
34541	dimethylarsinite methyltransferase activity	F	Catalysis of the reaction: dimethylarsenous acid + R2S-CH3 = trimethylarsine oxide + R2SH.
34542	trimethylarsine oxidase activity	F	Catalysis of the reaction: trimethylarsine oxide + 2 H+ + 2 e- = trimethylarsine + H2O.
34543	5-aminosalicylate dioxygenase activity	F	Catalysis of the reaction: 5-aminosalicylate + O2 = cis-4-amino-6-carboxy-2-oxo-hexa-3,5-dienoate.
34544	trans-ACOHDA hydrolase activity	F	Catalysis of the reaction: trans-4-amino-6-carboxy-2-oxo-hexa-3,5-dienoate + H2O = fumarylpyruvate + NH3.
34545	fumarylpyruvate hydrolase activity	F	Catalysis of the reaction: fumarylpyruvate + H2O = fumarate + pyruvate + H+.
34546	2,4-dichloroaniline reductive dehalogenase activity	F	Catalysis of the reaction: 2,4-dichloroaniline + 2 H+ + 2 e- = 4-chloroaniline + HCl.
34547	N-cyclopropylmelamine deaminase activity	F	Catalysis of the reaction: cyromazine + H2O = N-cyclopropylammeline + NH3.
34548	N-cyclopropylammeline deaminase activity	F	Catalysis of the reaction: N-cyclopropylammeline + H2O = N-cyclopropylammelide + NH3.
34549	N-cyclopropylammelide alkylamino hydrolase activity	F	Catalysis of the reaction: N-cyclopropylammelide + H2O = cyclopropylamine + cyanuric acid.
34550	dimethylarsinate reductase activity	F	Catalysis of the reaction: dimethylarsinate + 3 H+ + 2 e- = dimethylarsinous acid + H2O.
34551	mitochondrial respiratory chain complex III assembly	P	The aggregation, arrangement and bonding together of a set of components to form the cytochrome bc(1) complex (also known as ubiquinol-cytochrome c reductase), in the mitochondrial inner membrane.
34552	respiratory chain complex II assembly	P	The aggregation, arrangement and bonding together of a set of components to form respiratory chain complex II.
34553	mitochondrial respiratory chain complex II assembly	P	The aggregation, arrangement and bonding together of a set of components to form respiratory chain complex II, in the mitochondrial inner membrane.
34554	3,3',5-tribromobisphenol A reductive dehalogenase activity	F	Catalysis of the reaction: 3,3',5-tribromobisphenol A + 2 H+ + 2 e- = 3,3'-dibromobisphenol A + HBr.
34555	3,3'-dibromobisphenol A reductive dehalogenase activity	F	Catalysis of the reaction: 3,3'-dibromobisphenol A + 2 H+ + 2 e- = 3-monobromobisphenol A + HBr.
34556	nitrobenzoate nitroreductase activity	F	Catalysis of the reaction: o-nitrobenzoate + NADPH + H+ = o-hydroxylaminobenzoate + NADP+.
34557	2-hydroxylaminobenzoate reductase activity	F	Catalysis of the reaction: 2-hydroxylaminobenzoate + NAD(P)H = anthranilate + NAD(P)+ + H2O.
34558	technetium (VII) reductase activity	F	Catalysis of the reaction: pertechnetate ion + 3/2 H2 = technetium (IV) oxide + H2O + OH-.
34559	bisphenol A hydroxylase B activity	F	Catalysis of the reaction: bisphenol A + NADH + H+ + O2 = 1,2-bis(4-hydroxyphenyl)-2-propanol + NAD+ + H2O.
34560	bisphenol A hydroxylase A activity	F	Catalysis of the reaction: bisphenol A + NADH + H+ + O2 = 2,2-bis(4-hydroxyphenyl)-1-propanol + NAD+ + H2O.
34561	1,2-bis(4-hydroxyphenyl)-2-proponol dehydratase activity	F	Catalysis of the reaction: 1,2-bis(4-hydroxyphenyl)-2-propanol = 4,4'-dihydroxy-alpha-methylstilbene + H2O.
34562	2,2-bis(4-hydroxyphenyl)-1-propanol hydroxylase activity	F	Catalysis of the reaction: 2,2-bis(4-hydroxyphenyl)-1-propanol + NADH + H+ + O2 = 2,3-bis(4-hydroxyphenyl)-1,2-propanediol + NAD+ + H2O.
34563	2,3-bis(4-hydroxyphenyl)-1,2-propanediol dioxygenase activity	F	Catalysis of the reaction: 2,3-bis(4-hydroxyphenyl)-1,2-propanediol + O2 = 4-hydroxyphenacyl alcohol + 4-hydroxybenzoate + 2 H+ + 2 e-.
34564	4,4'-dihydroxy-alpha-methylstilbene dioxygenase activity	F	Catalysis of the reaction: 4,4'-dihydroxy-alpha-methylstilbene + O2 = 4-hydroxybenzaldehyde + 4-hydroxyacetophenone + 2 H+ + 2 e-.
34565	1-nitro-1,2-dihydro-1,3,5-triazine hydrolase activity	F	Catalysis of the reaction: 1-nitro-1,2-dihydro-1,3,5-triazine + 2 H2O = 1-nitro-1,3,5-triazinane-2,4-diol.
34567	chromate reductase activity	F	Catalysis of the reaction: chromate = chromium (III).
34568	isoproturon dimethylaminedehydrogenase activity	F	Catalysis of the reaction: isoproturon + H2O = formaldehyde + monodemethylisoproturon + 2 H+ + 2 e-.
34569	monodemethylisoproturon dehydrogenase activity	F	Catalysis of the reaction: monodemethylisoproturon + H2O = hydroxymonodemethylisoproturon + 2 H+ + 2 e-.
34570	hydroxymonomethylisoproturon dimethylaminedehydrogenase activity	F	Catalysis of the reaction: hydroxymonodemethylisoproturon + H2O = formaldehyde + 4'-(2-hydroxyisopropyl)phenylurea + 2 H+ + 2 e-.
34571	4'-(2-hydroxyisopropyl)phenylurea amidohydrolase activity	F	Catalysis of the reaction: 4'-(2-hydroxyisopropyl)phenylurea + H2O = 4'-(2-hydroxyisopropyl)phenylaniline + carbamic acid.
34572	monodemethylisoproturon dimethylaminedehydrogenase activity	F	Catalysis of the reaction: monodemethylisoproturon + H2O = didemethylisoproturon + formaldehyde + 2 H+ + 2 e-.
34573	didemethylisoproturon amidohydrolase activity	F	Catalysis of the reaction: didemethylisoproturon + H2O = carbamic acid + 4-isopropylaniline.
34574	didemethylisoproturon dehydrogenase activity	F	Catalysis of the reaction: didemethylisoproturon + H2O = 4'-(2-hydroxyisopropyl)phenylurea + 2 H+ + 2 e-.
34575	4-isopropylaniline dehydrogenase activity	F	Catalysis of the reaction: 4-isopropylaniline + H2O = 4'-(2-hydroxyisopropyl)phenylaniline + 2 H+ + 2 e-.
34576	N-isopropylacetanilide amidohydrolase activity	F	Catalysis of the reaction: N-isopropylacetanilide + OH- = N-isopropylaniline + acetate.
34577	N-isopropylacetaniline monooxygenase activity	F	Catalysis of the reaction: N-isopropylacetanilide + 1/2 O2 = acetanilide + acetone.
34578	limonene 8-hydratase activity	F	Catalysis of the reaction: limonene + H2O = alpha-terpineol.
34579	(1-methylpentyl)succinate synthase activity	F	Catalysis of the reaction: fumarate + n-hexane = (1-methylpentyl)succinate.
34580	4-methyloctanoyl-CoA dehydrogenase activity	F	Catalysis of the reaction: 4-methyloctanoyl-CoA = 4-methyloct-2-enoyl-CoA + 2 H+ + 2 e-.
34581	4-methyloct-2-enoyl-CoA hydratase activity	F	Catalysis of the reaction: 4-methyloct-2-enoyl-CoA + H2O = 3-hydroxy-4-methyloctanoyl-CoA.
34582	3-hydroxy-4-methyloctanoyl-CoA dehydrogenase activity	F	Catalysis of the reaction: 3-hydroxy-4-methyloctanoyl-CoA = 4-methyl-3-oxooctanoyl-CoA + 2 H+ + 2 e-.
34583	21U-RNA binding	F	Interacting selectively and non-covalently with a 21U-RNA, a 21-nucleotide RNA characterized by a uridine 5'-monophosphate and a modified 3' end resistant to periodate degradation. 21U-RNAs are derived from distinct, autonomously expressed loci within the genome.
34584	piRNA binding	F	Interacting selectively and non-covalently with a piRNA, a Piwi-associated RNA, a 24- to 30-nucleotide RNA derived from repeat or complex DNA sequence elements and processed by a Dicer-independent mechanism.
34585	21U-RNA metabolic process	P	The chemical reactions and pathways involving 21U-RNAs, a class of single-stranded RNA molecules of about 21 nucleotides in length characterized by a uridine 5'-monophosphate and a modified 3' end resistant to periodate degradation. 21U-RNAs are derived from distinct, autonomously expressed loci within the genome.
34586	21U-RNA catabolic process	P	The chemical reactions and pathways resulting in the breakdown of 21U-RNAs, a class of single-stranded RNA molecules of about 21 nucleotides in length characterized by a uridine 5'-monophosphate and a modified 3' end resistant to periodate degradation. 21U-RNAs are derived from distinct, autonomously expressed loci within the genome.
34587	piRNA metabolic process	P	The chemical reactions and pathways involving piRNAs, Piwi-associated RNAs, a class of 24- to 30-nucleotide RNA derived from repeat or complex DNA sequence elements and processed by a Dicer-independent mechanism.
34588	piRNA catabolic process	P	The chemical reactions and pathways resulting in the breakdown of piRNAs, Piwi-associated RNAs, a class of 24- to 30-nucleotide RNA derived from repeat or complex DNA sequence elements and processed by a Dicer-independent mechanism.
34589	hydroxyproline transport	P	The directed movement of hydroxyproline into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
34590	L-hydroxyproline transmembrane transporter activity	F	Enables the transfer of L-hydroxyproline from one side of a membrane to the other.
34591	rhoptry lumen	C	The volume enclosed by the rhoptry membrane.
34592	synaptic vesicle lumen	C	The volume enclosed by the synaptic vesicle membrane.
34593	phosphatidylinositol bisphosphate phosphatase activity	F	Catalysis of the reaction: phosphatidylinositol bisphosphate + H2O = phosphatidylinositol phosphate + phosphate.
34594	phosphatidylinositol trisphosphate phosphatase activity	F	Catalysis of the reaction: phosphatidylinositol trisphosphate + H2O = phosphatidylinositol bisphosphate + phosphate.
34595	phosphatidylinositol phosphate 5-phosphatase activity	F	Catalysis of the removal of the 5-phosphate group of a phosphatidylinositol phosphate.
34596	phosphatidylinositol phosphate 4-phosphatase activity	F	Catalysis of the removal of the 4-phosphate group of a phosphatidylinositol phosphate.
34597	phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity	F	Catalysis of the reaction: 1-phosphatidyl-myo-inositol 4,5-bisphosphate + H2O = 1-phosphatidyl-1D-myo-inositol 3-phosphate + phosphate.
34598	phosphothreonine lyase activity	F	Catalysis of the removal of the phosphate group from phosphothreonine by cleavage of the C-OP bond with the concomitant abstraction of the alpha proton, generating a double bond-containing product.
34599	cellular response to oxidative stress	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
34601	oxoglutarate dehydrogenase [NAD(P)+] activity	F	Catalysis of the reaction: 2-oxoglutarate + CoA + NAD(P)+ = succinyl-CoA + CO2 + NAD(P)H.
34602	oxoglutarate dehydrogenase (NAD+) activity	F	Catalysis of the reaction: 2-oxoglutarate + CoA + NAD+ = succinyl-CoA + CO2 + NADH.
34603	pyruvate dehydrogenase [NAD(P)+] activity	F	Catalysis of the reaction: pyruvate + CoA + NAD(P)+ = acetyl-CoA + CO2 + NAD(P)H.
34604	pyruvate dehydrogenase (NAD+) activity	F	Catalysis of the reaction: pyruvate + CoA + NAD+ = acetyl-CoA + CO2 + NADH.
34605	cellular response to heat	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.
34606	response to hermaphrodite contact	P	The response by the male to a hermaphrodite after initial contact following mate finding. The male stops forward locomotion, presses the ventral side of his tail against his partner's body, and begins moving backward along the hermaphrodite. Male response behavior is initiated when sensory neurons located in the rays of his tail contact a potential mate.
34607	turning behavior involved in mating	P	The sharp ventral turn performed by the male as he approaches either the hermaphrodite head or tail, whilst trying to locate his partner's vulva. Turning occurs via a sharp ventral coil of the male's tail.
34608	vulval location	P	Location, by the male, of his partner's vulva when backing along the ventral side of the hermaphrodite during mating. The male stops at the vulva, coordinates his movements to the hermaphrodite's, and positions his tail precisely over the vulva so that he may insert his spicules and ejaculate.
34609	spicule insertion	P	Insertion of the male copulatory spicules into the hermaphrodite. Spicule insertion behavior initiates when the male cloaca contacts the vulva. During most mating encounters, the spicule tips will prod the vulva continuously until they partially penetrate, which then causes the protractors to contract completely so that the spicules extend through the vulva.
34610	oligodeoxyribonucleotidase activity	F	Catalysis of the exonucleolytic cleavage of oligodeoxyribonucleotides to yield deoxyribonucleoside 5'-phosphates.
34611	oligoribonucleotidase activity	F	Catalysis of the exonucleolytic cleavage of oligoribonucleotides to yield ribonucleoside 5'-phosphates.
34612	response to tumor necrosis factor	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tumor necrosis factor stimulus.
34613	cellular protein localization	P	Any process in which a protein is transported to, and/or maintained in, a specific location at the level of a cell. Localization at the cellular level encompasses movement within the cell, from within the cell to the cell surface, or from one location to another at the surface of a cell.
34614	cellular response to reactive oxygen species	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a reactive oxygen species stimulus. Reactive oxygen species include singlet oxygen, superoxide, and oxygen free radicals.
34615	GCH1 complex	C	A protein complex that possesses GTP cyclohydrolase I activity. In E. coli and human, the complex is a homodecamer, and monomers are catalytically inactive.
34616	response to laminar fluid shear stress	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a laminar fluid shear stress stimulus. Laminar fluid flow is the force acting on an object in a system where the fluid is moving across a solid surface in parallel layers. As an example, laminar shear stress can be seen where blood flows against the luminal side of blood vessel walls.
34617	tetrahydrobiopterin binding	F	Interacting selectively and non-covalently with a tetrahydrobiopterin, 5,6,7,8-tetrahydrobiopterin or a derivative thereof; tetrahydrobiopterins are enzyme cofactors that carry electrons in redox reactions.
34618	arginine binding	F	Interacting selectively and non-covalently with 2-amino-5-(carbamimidamido)pentanoic acid.
34620	cellular response to unfolded protein	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an unfolded protein stimulus.
34622	cellular macromolecular complex assembly	P	The aggregation, arrangement and bonding together of a set of macromolecules to form a complex, carried out at the cellular level.
34624	DNA recombinase assembly involved in gene conversion at mating-type locus	P	The aggregation, arrangement and bonding together of strand exchange proteins (recombinases) into higher order oligomers on single-stranded DNA, involved in the conversion of the mating-type locus from one allele to another.
34625	fatty acid elongation, monounsaturated fatty acid	P	Elongation of a fatty acid chain into which one C-C double bond has been introduced.
34626	fatty acid elongation, polyunsaturated fatty acid	P	Elongation of a fatty acid chain into which two or more C-C double bonds have been introduced.
34627	'de novo' NAD biosynthetic process	P	The chemical reactions and pathways resulting in the formation of nicotinamide adenine dinucleotide (NAD), beginning with the synthesis of tryptophan or aspartate from simpler precursors; biosynthesis may be of either the oxidized form, NAD, or the reduced form, NADH.
34628	'de novo' NAD biosynthetic process from aspartate	P	The chemical reactions and pathways resulting in the formation of nicotinamide adenine dinucleotide (NAD), beginning with the synthesis of aspartate from simpler precursors; biosynthesis may be of either the oxidized form, NAD, or the reduced form, NADH.
34629	cellular protein complex localization	P	A protein complex localization process that takes place at the cellular level; as a result, a protein complex is transported to, or maintained in, a specific location within a cell.
34630	RITS complex localization	P	Any process in which a RITS complex is transported to, or maintained in, a specific location.
34631	microtubule anchoring at spindle pole body	P	Any process in which a microtubule is maintained in a specific location in a cell by attachment to a spindle pole body. Microtubules attach to spindle pole bodies at the minus end.
34632	retinol transporter activity	F	Enables the directed movement of retinol into, out of or within a cell, or between cells. Retinol is vitamin A1, 2,6,6-trimethyl-1-(9'-hydroxy-3',7'-dimethylnona-1',3',5',7'-tetraenyl)cyclohex-1-ene, one of the three components that makes up vitamin A.
34633	retinol transport	P	The directed movement of retinol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Retinol is vitamin A1, 2,6,6-trimethyl-1-(9'-hydroxy-3',7'-dimethylnona-1',3',5',7'-tetraenyl)cyclohex-1-ene, one of the three components that makes up vitamin A.
34634	glutathione transmembrane transporter activity	F	Enables the directed movement of glutathione, the tripeptide glutamylcysteinylglycine, across a membrane into, out of or within a cell, or between cells.
34635	glutathione transport	P	The directed movement of glutathione, the tripeptide glutamylcysteinylglycine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
34636	strand invasion involved in gene conversion at mating-type locus	P	The process in which the nucleoprotein complex (composed of the broken single-strand DNA and the recombinase) searches and identifies a region of homology in intact duplex DNA at the mating-type locus. The broken single-strand DNA displaces the like strand and forms Watson-Crick base pairs with its complement, forming a duplex in which each strand is from one of the two recombining DNA molecules. This process occurs as part of gene conversion at the mating-type locus.
34637	cellular carbohydrate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y, carried out by individual cells.
34638	phosphatidylcholine catabolic process	P	The chemical reactions and pathways resulting in the breakdown of phosphatidylcholines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of choline.
34639	L-amino acid efflux transmembrane transporter activity	F	Catalysis of the transfer of an L-amino acid from the inside of the cell to the outside of the cell across a membrane.
34640	establishment of mitochondrion localization by microtubule attachment	P	The directed movement of a mitochondrion by attachment to a microtubule, followed by elongation of the microtubule by tubulin polymerization.
34641	cellular nitrogen compound metabolic process	P	The chemical reactions and pathways involving various organic and inorganic nitrogenous compounds, as carried out by individual cells.
34642	mitochondrion migration along actin filament	P	The directed movement of a mitochondrion along a microfilament, mediated by motor proteins.
34643	establishment of mitochondrion localization, microtubule-mediated	P	The directed movement of the mitochondrion to a specific location, by a process involving microtubules.
34644	cellular response to UV	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ultraviolet radiation (UV light) stimulus. Ultraviolet radiation is electromagnetic radiation with a wavelength in the range of 10 to 380 nanometers.
34645	cellular macromolecule biosynthetic process	P	The chemical reactions and pathways resulting in the formation of a macromolecule, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, carried out by individual cells.
34646	organelle-enclosing lipid monolayer	C	A lipid monolayer that surrounds and encloses an organelle.
34647	histone demethylase activity (H3-trimethyl-K4 specific)	F	Catalysis of the removal of a methyl group from trimethylated lysine at position 4 of the histone H3 protein.
34648	histone demethylase activity (H3-dimethyl-K4 specific)	F	Catalysis of the removal of a methyl group from dimethylated lysine at position 4 of the histone H3 protein.
34649	histone demethylase activity (H3-monomethyl-K4 specific)	F	Catalysis of the reaction: histone H3 N6-methyl-L-lysine (position 4) + O2 + FAD + H2O = histone H3 L-lysine (position 4) + H2O2 + formaldehyde + FADH2. This reaction is the removal of a methyl group from monomethylated lysine at position 4 of the histone H3 protein.
34650	cortisol metabolic process	P	The chemical reactions and pathways involving cortisol, the steroid hormone 11-beta-17,21-trihydroxypregn-4-ene-3,20-dione. Cortisol is synthesized from cholesterol in the adrenal gland and controls carbohydrate, fat and protein metabolism and has anti-inflammatory properties.
34651	cortisol biosynthetic process	P	The chemical reactions and pathways resulting in the formation of cortisol, the steroid hormone 11-beta-17,21-trihydroxypregn-4-ene-3,20-dione. Cortisol is synthesized from cholesterol in the adrenal gland and controls carbohydrate, fat and protein metabolism and has anti-inflammatory properties.
34652	extrachromosomal circular DNA localization involved in cell aging	P	A process in which extrachromosomal circular DNA molecules are transported to, or maintained in, a specific location in cells contributing to their aging.
34653	retinoic acid catabolic process	P	The chemical reactions and pathways resulting in the breakdown of retinoic acid, one of the three components that makes up vitamin A.
34654	nucleobase-containing compound biosynthetic process	P	The chemical reactions and pathways resulting in the formation of nucleobases, nucleosides, nucleotides and nucleic acids.
34655	nucleobase-containing compound catabolic process	P	The chemical reactions and pathways resulting in the breakdown of nucleobases, nucleosides, nucleotides and nucleic acids.
34656	nucleobase-containing small molecule catabolic process	P	The chemical reactions and pathways resulting in the breakdown of a nucleobase-containing small molecule: a nucleobase, a nucleoside, or a nucleotide.
34657	GID complex	C	A protein complex with ubiquitin ligase activity that is involved in proteasomal degradation of fructose-1,6-bisphosphatase (FBPase) and phosphoenolpyruvate carboxykinase during the transition from gluconeogenic to glycolytic growth conditions. In S. cerevisiae, the GID (Glucose Induced degradation Deficient) complex consists of Vid30p, Rmd5p, Vid24p, Vid28p, Gid7p, Gid8p, and Fyv10p.
34658	isopropylmalate transmembrane transporter activity	F	Enables the transfer of isopropylmalate from one side of the membrane to the other.
34659	isopropylmalate transport	P	The directed movement of isopropylmalate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
34660	ncRNA metabolic process	P	The chemical reactions and pathways involving non-coding RNA transcripts (ncRNAs).
34661	ncRNA catabolic process	P	The chemical reactions and pathways resulting in the breakdown of non-coding RNA transcripts (ncRNAs). Includes the breakdown of cryptic unstable transcripts (CUTs).
34662	CFTR-NHERF-ezrin complex	C	A protein complex that contains ezrin, Na+/H+ exchanger regulatory factor (NHERF, also called EBP50), and two copies of the cystic fibrosis transmembrane conductance regulator (CFTR). The CFTR molecules interact with NHERF via their cytoplasmic tail domains; the complex is thought to link the CFTR channel to the actin cytoskeleton and contribute to the regulation of channel activity.
34663	endoplasmic reticulum chaperone complex	C	A protein complex that is located in the endoplasmic reticulum and is composed of chaperone proteins, including BiP, GRP94; CaBP1, protein disulfide isomerase (PDI), ERdj3, cyclophilin B, ERp72, GRP170, UDP-glucosyltransferase, and SDF2-L1.
34664	Ig heavy chain-bound endoplasmic reticulum chaperone complex	C	A protein complex that is located in the endoplasmic reticulum (ER) and is formed by the association of an immunoglobulin heavy chain with the proteins of the ER chaperone complex; the latter include BiP, GRP94; CaBP1, protein disulfide isomerase (PDI), ERdj3, cyclophilin B, ERp72, GRP170, UDP-glucosyltransferase, and SDF2-L1.
34665	integrin alpha1-beta1 complex	C	An integrin complex that comprises one alpha1 subunit and one beta1 subunit.
34666	integrin alpha2-beta1 complex	C	An integrin complex that comprises one alpha2 subunit and one beta1 subunit.
34667	integrin alpha3-beta1 complex	C	An integrin complex that comprises one alpha3 subunit and one beta1 subunit.
34668	integrin alpha4-beta1 complex	C	An integrin complex that comprises one alpha4 subunit and one beta1 subunit.
34669	integrin alpha4-beta7 complex	C	An integrin complex that comprises one alpha4 subunit and one beta7 subunit.
34670	chemotaxis to arachidonic acid	P	The directed movement of a motile cell or organism in response to the presence of arachidonic acid.
34671	retinoic acid receptor signaling pathway involved in pronephros anterior/posterior pattern specification	P	The series of molecular signals generated as a consequence of a retinoic acid receptor binding to one of its physiological ligands that results in the spatial identity of regions along the anterior-posterior axis of the pronephros.
34672	anterior/posterior pattern specification involved in pronephros development	P	The developmental process that results in the creation of defined areas or spaces within the pronephros along the anterior/posterior axis to which cells respond and eventually are instructed to differentiate.
34673	inhibin-betaglycan-ActRII complex	C	A protein complex that consists of inhibin, type III transforming growth factor beta receptor (also known as betaglycan), and the type II activin receptor ActRII. The complex is thought to negatively regulate the activity of activin B.
34674	integrin alpha5-beta1 complex	C	An integrin complex that comprises one alpha5 subunit and one beta1 subunit.
34675	integrin alpha6-beta1 complex	C	An integrin complex that comprises one alpha6 subunit and one beta1 subunit.
34676	integrin alpha6-beta4 complex	C	An integrin complex that comprises one alpha6 subunit and one beta4 subunit.
34677	integrin alpha7-beta1 complex	C	An integrin complex that comprises one alpha7 subunit and one beta1 subunit.
34678	integrin alpha8-beta1 complex	C	An integrin complex that comprises one alpha8 subunit and one beta1 subunit.
34679	integrin alpha9-beta1 complex	C	An integrin complex that comprises one alpha9 subunit and one beta1 subunit.
34680	integrin alpha10-beta1 complex	C	An integrin complex that comprises one alpha10 subunit and one beta1 subunit.
34681	integrin alpha11-beta1 complex	C	An integrin complex that comprises one alpha11 subunit and one beta1 subunit.
34682	integrin alphav-beta1 complex	C	An integrin complex that comprises one alphav subunit and one beta1 subunit.
34683	integrin alphav-beta3 complex	C	An integrin complex that comprises one alphav subunit and one beta3 subunit.
34684	integrin alphav-beta5 complex	C	An integrin complex that comprises one alphav subunit and one beta5 subunit.
34685	integrin alphav-beta6 complex	C	An integrin complex that comprises one alphav subunit and one beta6 subunit.
34686	integrin alphav-beta8 complex	C	An integrin complex that comprises one alphav subunit and one beta8 subunit.
34687	integrin alphaL-beta2 complex	C	An integrin complex that comprises one alphaL subunit and one beta2 subunit.
34688	integrin alphaM-beta2 complex	C	An integrin complex that comprises one alphaM subunit and one beta2 subunit.
34689	integrin alphaX-beta2 complex	C	An integrin complex that comprises one alphaX subunit and one beta2 subunit.
34690	integrin alphaD-beta2 complex	C	An integrin complex that comprises one alphaD subunit and one beta2 subunit.
34691	integrin alphaE-beta7 complex	C	An integrin complex that comprises one alphaE subunit and one beta7 subunit.
34692	E.F.G complex	C	A protein complex that comprises three core spliceosomal proteins, designated E, F, and G. Formation of the E.F.G complex is essential but not sufficient for the formation of a stable U1 snRNP complex.
34693	U11/U12 snRNP	C	A ribonucleoprotein complex formed by the association of the U11 and U12 small nuclear ribonucleoproteins.
34694	response to prostaglandin	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin stimulus.
34695	response to prostaglandin E	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin E stimulus.
34696	response to prostaglandin F	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin F stimulus.
34697	response to prostaglandin I	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin I stimulus.
34698	response to gonadotropin	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gonadotropin stimulus.
34699	response to luteinizing hormone	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a luteinizing hormone stimulus.
34700	allulose 6-phosphate 3-epimerase activity	F	Catalysis of the reaction: D-allulose 6-phosphate = D-fructose 6-phosphate.
34701	tripeptidase activity	F	Catalysis of the hydrolysis of a tripeptide.
34702	ion channel complex	C	A protein complex that spans a membrane and forms a water-filled channel across the phospholipid bilayer allowing selective ion transport down its electrochemical gradient.
34703	cation channel complex	C	An ion channel complex through which cations pass.
34704	calcium channel complex	C	An ion channel complex through which calcium ions pass.
34705	potassium channel complex	C	An ion channel complex through which potassium ions pass.
34706	sodium channel complex	C	An ion channel complex through which sodium ions pass.
34707	chloride channel complex	C	An ion channel complex through which chloride ions pass.
34708	methyltransferase complex	C	A protein complex that possesses methyltransferase activity.
34709	methylosome	C	A large (20 S) protein complex that possesses protein arginine methyltransferase activity and modifies specific arginines to dimethylarginines in the arginine- and glycine-rich domains of several spliceosomal Sm proteins, thereby targeting these proteins to the survival of motor neurons (SMN) complex for assembly into small nuclear ribonucleoprotein (snRNP) core particles. Proteins found in the methylosome include the methyltransferase JBP1 (PRMT5), pICln (CLNS1A), MEP50 (WDR77), and unmethylated forms of SM proteins that have RG domains.
34710	inhibin complex binding	F	Interacting selectively and non-covalently with an inhibin complex, a dimer of one inhibin-alpha subunit and one inhibin-beta subunit.
34711	inhibin binding	F	Interacting selectively and non-covalently with an inhibin monomer, any of the polypeptides that combine to form activin and inhibin dimers.
34713	type I transforming growth factor beta receptor binding	F	Interacting selectively and non-covalently with a type I transforming growth factor beta receptor.
34714	type III transforming growth factor beta receptor binding	F	Interacting selectively and non-covalently with a type III transforming growth factor beta receptor.
34715	pICln-Sm protein complex	C	A protein complex that contains pICln (CLNS1A) and several Sm proteins, including SmD1, SmD2, SmE, SmF, and SmG.
34716	Gemin3-Gemin4-Gemin5 complex	C	A protein complex that contains Gemin3 (DDX20), Gemin4, and Gemin5, and can bind to snRNAs; may be an intermediate in SMN complex assembly.
34717	Gemin6-Gemin7-unrip complex	C	A protein complex that contains Gemin6, Gemin7, and unrip (STRAP), and can bind to snRNAs; may play a role in snRNP assembly.
34718	SMN-Gemin2 complex	C	A protein complex that contains the survival motor neuron (SMN) protein and Gemin2; may form the stable core of the larger SMN complex.
34719	SMN-Sm protein complex	C	A protein complex formed by the association of several methylated Sm proteins with the SMN complex; the latter contains the survival motor neuron (SMN) protein and at least eight additional integral components, including the Gemin2-8 and unrip proteins; additional proteins, including galectin-1 and galectin-3, are also found in the SMN-SM complex. The SMN-Sm complex is involved in spliceosomal snRNP assembly in the cytoplasm.
34720	histone H3-K4 demethylation	P	The modification of histone H3 by the removal of a methyl group from lysine at position 4 of the histone.
34721	histone H3-K4 demethylation, trimethyl-H3-K4-specific	P	The modification of histone H3 by the removal of a methyl group from a trimetylated lysine at position 4 of the histone.
34722	gamma-glutamyl-peptidase activity	F	Catalysis of the cleavage of a gamma-linked glutamate bond.
34723	DNA replication-dependent nucleosome organization	P	The formation or destruction of chromatin structures on newly replicated DNA, coupled to strand elongation.
34724	DNA replication-independent nucleosome organization	P	The formation or destruction of chromatin structures, occurring outside the context of DNA replication.
34725	DNA replication-dependent nucleosome disassembly	P	The controlled breakdown of nucleosomes on newly replicated DNA, coupled to strand elongation.
34726	DNA replication-independent nucleosome disassembly	P	The controlled breakdown of nucleosomes outside the context of DNA replication.
34727	piecemeal microautophagy of nucleus	P	Degradation of a cell nucleus by lysosomal microautophagy.
34728	nucleosome organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of one or more nucleosomes.
34729	histone H3-K79 methylation	P	The modification of histone H3 by addition of a methyl group to lysine at position 79 of the histone.
34730	SmD-containing SMN-Sm protein complex	C	An SMN-Sm protein complex formed by the association of the methylated Sm proteins B/B', D1, D2, D3, E, F, and G with the SMN complex.
34731	Lsm-containing SMN-Sm protein complex	C	An SMN-Sm protein complex formed by the association of the methylated Sm proteins B/B', D3, E, F, and G, and Lsm10 and Lsm11, with the SMN complex. This complex forms Sm cores on U7 snRNA.
34732	transcription factor TFIIIB-alpha complex	C	A transcription factor TFIIIB-beta complex that contains the TATA-binding protein (TBP), B'' and a specialized homolog of the conserved subunit BRF referred to as BRFU or TFIIIB50, which found in human but not conserved in yeast; the complex is involved in the regulation of transcription from type 3 (upstream) RNA polymerase III promoters.
34733	transcription factor TFIIIB-beta complex	C	A transcription factor TFIIIB-beta complex that contains the TATA-binding protein (TBP), B'' and BRF, and is involved in the regulation of transcription from type 2 RNA polymerase III promoters.
34734	transcription factor TFIIIC1 complex	C	A transcription factor complex that forms part of the TFIIIC complex, observed in human. The complex is poorly characterized, but contains the 250-kDa form of HsBdp1, and is thought to include nuclear factor 1 (NF1). It stimulates binding by human TFIIIC2 and is required for transcription activity.
34735	transcription factor TFIIIC2 complex	C	A transcription factor complex that forms part of the TFIIIC complex, observed in human; composed of five subunits (GTF3C1/hTFIIIC220/TFIIICalpha, GTF3C2/hTFIIIC110/TFIIICbeta, GTF3C3/hTFIIIC102/TFIIICgamma, GTF3C4/hTFIIIC90/TFIIICdelta and GTF3C5/hTFIIIC63/TFIIICepsilon in human) that together recognize the type 2 RNA polymerase III promoter.
34736	cholesterol O-acyltransferase activity	F	Catalysis of the reaction: acyl-CoA + cholesterol = a cholesterol ester + CoA.
34737	ergosterol O-acyltransferase activity	F	Catalysis of the reaction: acyl-CoA + ergosterol = CoA + ergosterol ester.
34738	lanosterol O-acyltransferase activity	F	Catalysis of the reaction: acyl-CoA + lanosterol = CoA + lanosterol ester.
34739	histone deacetylase activity (H4-K16 specific)	F	Catalysis of the reaction: histone H4 N6-acetyl-L-lysine (position 16) + H2O = histone H4 L-lysine (position 16) + acetate. This reaction represents the removal of an acetyl group from lysine at position 16 of the histone H4 protein.
34740	TFIIIC-TOP1-SUB1 complex	C	A protein complex that contains TFIIIC, topoisomerase 1, and Sub1/PC4. Characterized in human, the complex is involved in regulating transcription from RNA polymerase III (Pol III) promoters. Topoisomerase 1 and Sub1 enhance the accuracy of transcription termination, and promote reinitiation by Pol III.
34741	APC-tubulin-IQGAP1 complex	C	A protein complex that contains the tumor suppressor protein adenomatous polyposis coli (APC), alpha-tubulin, gamma-tubulin, and the Rac1 and Cdc42 effector IQGAP1; may play a role in cytoskeleton organization.
34743	APC-IQGAP complex	C	A protein complex that contains the tumor suppressor protein adenomatous polyposis coli (APC) and the Rac1 and Cdc42 effector IQGAP1; may play a role in cytoskeleton organization and cell migration.
34744	APC-IQGAP1-Cdc42 complex	C	A protein complex that contains the tumor suppressor protein adenomatous polyposis coli (APC), the small GTPase Cdc42, and the Rac1 and Cdc42 effector IQGAP1; may play a role in cytoskeleton organization and cell migration.
34745	APC-IQGAP1-Rac1 complex	C	A protein complex that contains the tumor suppressor protein adenomatous polyposis coli (APC), the small GTPase Rac1, and the Rac1 and Cdc42 effector IQGAP1; may play a role in cytoskeleton organization and cell migration.
34746	APC-IQGAP1-CLIP-170 complex	C	A protein complex that contains the tumor suppressor protein adenomatous polyposis coli (APC), the small GTPase Cdc42, and CLIP-170; may play a role in cytoskeleton organization and cell migration.
34748	Par3-APC-KIF3A complex	C	A protein complex that contains Par3, the tumor suppressor protein adenomatous polyposis coli (APC), and the kinesin-related protein KIF3A; involved in establishing neuronal cell polarity.
34749	Scrib-APC complex	C	A protein complex that contains the Scribble protein (a cell polarity determinant) and the tumor suppressor protein adenomatous polyposis coli (APC); may be involved in the control of cell proliferation.
34750	Scrib-APC-beta-catenin complex	C	A protein complex that contains the Scribble protein (a cell polarity determinant), the tumor suppressor protein adenomatous polyposis coli (APC), and beta-catenin; may be involved in the control of cell proliferation.
34751	aryl hydrocarbon receptor complex	C	A protein complex that acts as an aryl hydrocarbon (Ah) receptor. Cytosolic and nuclear Ah receptor complexes have different subunit composition, but both contain the ligand-binding subunit AhR.
34752	cytosolic aryl hydrocarbon receptor complex	C	An aryl hydrocarbon receptor complex found in the cytosol, in which the ligand-binding subunit AhR is not bound to ligand; consists of AhR, two molecules of HSP90, the protein kinase c-Src, and the immunophilin XAP2/AIP.
34753	nuclear aryl hydrocarbon receptor complex	C	An aryl hydrocarbon receptor (AhR) complex found in the nucleus;; consists of ligand-bound AhR and the aryl hydrocarbon receptor nuclear translocator (ARNT).
34754	cellular hormone metabolic process	P	The chemical reactions and pathways involving any hormone, naturally occurring substances secreted by specialized cells that affects the metabolism or behavior of other cells possessing functional receptors for the hormone, as carried out by individual cells.
34755	iron ion transmembrane transport	P	A process in which an iron ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.
34756	regulation of iron ion transport	P	Any process that modulates the frequency, rate or extent of the directed movement of iron ions (Fe) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
34757	negative regulation of iron ion transport	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of iron ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
34758	positive regulation of iron ion transport	P	Any process that activates or increases the frequency, rate or extent of the directed movement of iron ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
34759	regulation of iron ion transmembrane transport	P	Any process that modulates the frequency, rate or extent of the directed movement of iron ions (Fe) from one side of a membrane to the other by means of some agent such as a transporter or pore.
34760	negative regulation of iron ion transmembrane transport	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of iron ions from one side of a membrane to the other by means of some agent such as a transporter or pore.
34761	positive regulation of iron ion transmembrane transport	P	Any process that activates or increases the frequency, rate or extent of the directed movement of iron ions from one side of a membrane to the other by means of some agent such as a transporter or pore.
34762	regulation of transmembrane transport	P	Any process that modulates the frequency, rate or extent of the directed movement of a solute from one side of a membrane to the other.
34763	negative regulation of transmembrane transport	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a solute from one side of a membrane to the other.
34764	positive regulation of transmembrane transport	P	Any process that activates or increases the frequency, rate or extent of the directed movement of a solute from one side of a membrane to the other.
34765	regulation of ion transmembrane transport	P	Any process that modulates the frequency, rate or extent of the directed movement of ions from one side of a membrane to the other.
34766	negative regulation of ion transmembrane transport	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of ions from one side of a membrane to the other.
34767	positive regulation of ion transmembrane transport	P	Any process that activates or increases the frequency, rate or extent of the directed movement of ions from one side of a membrane to the other.
34768	(E)-beta-ocimene synthase activity	F	Catalysis of the reaction: geranyl diphosphate = (E)-beta-ocimene + diphosphate.
34769	basement membrane disassembly	P	The controlled breakdown of the basement membrane in the context of a normal process such as imaginal disc eversion.
34770	histone H4-K20 methylation	P	The modification of histone H4 by addition of one or more methyl groups to lysine at position 20 of the histone.
34771	histone H4-K20 monomethylation	P	The modification of histone H4 by addition of one methyl group to lysine at position 20 of the histone.
34772	histone H4-K20 dimethylation	P	The modification of histone H4 by addition of two methyl groups to lysine at position 20 of the histone.
34773	histone H4-K20 trimethylation	P	The modification of histone H4 by addition of three methyl groups to lysine at position 20 of the histone.
34774	secretory granule lumen	C	The volume enclosed by the membrane of a secretory granule.
34775	glutathione transmembrane transport	P	A process in which glutathione is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.
34776	response to histamine	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a histamine stimulus. Histamine, the biogenic amine 2-(1H-imidazol-4-yl)ethanamine, is involved in local immune responses as well as regulating physiological function in the gut and acting as a neurotransmitter.
34777	recycling endosome lumen	C	The volume enclosed by the membranes of a recycling endosome.
34778	2-hydroxy-4-isopropenylcyclohexane-1-carboxyl-CoA dehydrogenase activity	F	Catalysis of the reaction: 2-hydroxy-4-isopropenylcyclohexane-1-carboxyl-CoA = 4-isopropenyl-2-ketocyclohexane-1-carboxyl-CoA + 2 H+ + 2 e-.
34779	4-isopropenyl-2-ketocyclohexane-1-carboxyl-CoA hydrolase activity	F	Catalysis of the reaction: 4-isopropenyl-2-ketocyclohexane-1-carboxyl-CoA + H2O = 3-isopropenylpimelyl-CoA.
34780	glyphosate dehydrogenase activity	F	Catalysis of the reaction: glyphosate + OH- = glyoxylate + aminomethylphosphonic acid + H+ + 2 e-.
34781	N-cyclohexylformamide amidohydrolase activity	F	Catalysis of the reaction: N-cyclohexylformamide + OH- = cyclohexylamine + formate.
34782	dimethylmalonate decarboxylase activity	F	Catalysis of the reaction: dimethylmalonate + H+ = isobutyrate + CO2.
34783	pivalate-CoA ligase activity	F	Catalysis of the reaction: pivalate + H+ + HSCoA + ATP = pivalyl-CoA + PPi + AMP.
34784	pivalyl-CoA mutase activity	F	Catalysis of the reaction: pivalyl-CoA = 3-methylbutyryl-CoA.
34785	salicylate 5-hydroxylase activity	F	Catalysis of the reaction: salicylate + O2 + NAD(P)H + H+ = gentisate + H2O + NAD(P)+.
34786	9-fluorenone-3,4-dioxygenase activity	F	Catalysis of the reaction: 9-fluorenone + O2 + 2 H+ + 2 e- = 1-hydro-1,1a-dihydroxy-9-fluorenone.
34787	1-hydro-1,1a-dihydroxy-9-fluorenone dehydrogenase activity	F	Catalysis of the reaction: 1-hydro-1,1a-dihydroxy-9-fluorenone + H2O = 2,3-dihydroxy-2'-carboxybiphenyl + 3 H+ + 2 e-.
34788	2,3-dihydroxy-2'-carboxybiphenyl 1,2-dioxygenase activity	F	Catalysis of the reaction: 2,3-dihydroxy-2'-carboxybiphenyl + O2 = 2-hydroxy-6-oxo-6-(2-carboxyphenyl)-hexa-2,4-dienoate + H+.
34789	2-hydroxy-6-oxo-6-(2-carboxyphenyl)-hexa-2,4-dienoate hydrolase activity	F	Catalysis of the reaction: 2-hydroxy-6-oxo-6-(2-carboxyphenyl)-hexa-2,4-dienoate + H2O = cis-2-hydroxypenta-2,4-dienoate + phthalate + H+.
34790	3,4-dihydroxy-3,4-dihydrofluorene dehydrogenase activity	F	Catalysis of the reaction: (+)-(3S,4R)-cis-3,4-dihydroxy-3,4-dihydrofluorene = 3,4-dihydroxyfluorene + 2 H+ + 2 e-.
34791	isobutylamine N-hydroxylase activity	F	Catalysis of the reaction: isobutylamine + NADPH + O2 = isobutylhydroxylamine + NADP+ + H2O.
34792	hypophosphite dioxygenase activity	F	Catalysis of the reaction: hypophosphite + 2-oxoglutarate + O2 = succinate + phosphite + CO2.
34793	cyclopropanecarboxylate-CoA ligase activity	F	Catalysis of the reaction: cyclopropanecarboxylate + CoASH = cyclopropanecarboxyl-CoA + OH-.
34794	cyclopropanecarboxyl-CoA decyclase activity	F	Catalysis of the reaction: cyclopropanecarboxyl-CoA = crotonoyl-CoA.
34795	cyclohexane monooxygenase activity	F	Catalysis of the reaction: cyclohexane + O2 + NAD(P)H + H+ = cyclohexanol + NAD(P)+ + H2O.
34796	adipate-CoA ligase activity	F	Catalysis of the reaction: adipate + CoASH = adipyl-CoA + OH-.
34797	fosfomycin 2-glutathione ligase activity	F	Catalysis of the reaction: hydrogen (2R,3S)-3-methyloxiran-2-ylphosphonic acid + glutathione = hydrogen (1R,2R)-1-glutathio-2-hydroxypropylphosphonic acid.
34798	fosfomycin 2-L-cysteine ligase activity	F	Catalysis of the reaction: hydrogen (2R,3S)-3-methyloxiran-2-ylphosphonic acid + L-cysteine = hydrogen (1R,2R)-1-L-cysteine-2-hydroxypropylphosphonic acid.
34799	dihydride TNP tautomerase activity	F	Catalysis of the reaction: TNP dihydride Meisenheimer complex (aci form) = TNP dihydride Meisenheimer complex (nitro form).
34800	trinitrophenol dihydride denitratase activity	F	Catalysis of the reaction: trinitrophenol dihydride Meisenheimer complex (aci form) = 2,4-dinitrophenol hydride Meisenheimer complex + NO2. Trinitrophenol is also known as TNP and dinitrophenol is also known as DNP.
34801	2,4-dinitrocyclohexanone hydrolase activity	F	Catalysis of the reaction: 2,4-dinitrocyclohexanone + OH- = 4,6-dinitrohexanoate.
34802	branched-chain dodecylbenzene sulfonate monooxygenase activity	F	Catalysis of the reaction: branched-chain dodecylbenzene sulfonate + 1/2 O2 + H+ = sulfurous acid + branched-chain dodecyl-4-hydroxy-benzene + sulfite.
34803	3-hydroxy-2-naphthoate 2,3-dioxygenase activity	F	Catalysis of the reaction: 3-hydroxy-2-naphthoate + O2 = (3E)-3-[(6Z)-6-(carboxymethylene)cyclohexa-2,4-dien-1-ylidene]-2-oxopropanate.
34804	benzo(a)pyrene 11,12-epoxidase activity	F	Catalysis of the reaction: benzo(a)pyrene + O2 = benzo(a)pyrene-11,12-epoxide.
34805	benzo(a)pyrene-trans-11,12-dihydrodiol dehydrogenase activity	F	Catalysis of the reaction: benzo(a)pyrene-trans-11,12-dihydrodiol = 11,12-dihydroxybenzo(a)pyrene + 2 H+ + 2 e-.
34806	benzo(a)pyrene 11,12-dioxygenase activity	F	Catalysis of the reaction: benzo(a)pyrene + O2 = benzo(a)pyrene-cis-11,12-dihydrodiol.
34807	4,5-dihydroxybenzo(a)pyrene methyltransferase activity	F	Catalysis of the reaction: 4,5-dihydroxybenzo(a)pyrene + C1 unit = hydroxymethoxybenzo(a)pyrene.
34808	benzo(a)pyrene 4,5-dioxygenase activity	F	Catalysis of the reaction: benzo(a)pyrene + O2 = benzo(a)pyrene-cis-4,5-dihydrodiol.
34809	benzo(a)pyrene-cis-4,5-dihydrodiol dehydrogenase activity	F	Catalysis of the reaction: benzo(a)pyrene-cis-4,5-dihydrodiol = 4,5-dihydroxybenzo(a)pyrene + H2.
34810	4,5-dihydroxybenzo(a)pyrene dioxygenase activity	F	Catalysis of the reaction: 4,5-dihydroxybenzo(a)pyrene + O2 = 4,5-chrysenedicarboxylate.
34811	benzo(a)pyrene 9,10-dioxygenase activity	F	Catalysis of the reaction: benzo(a)pyrene + O2 = benzo(a)pyrene-cis-9,10-dihydrodiol.
34812	9,10-dihydroxybenzo(a)pyrene dioxygenase activity	F	Catalysis of the reaction: 9,10-dihydroxybenzo(a)pyrene + O2 = cis-4-(8-hydroxypyren-7-yl)-2-oxobut-3-enoate.
34813	benzo(a)pyrene 7,8-dioxygenase activity	F	Catalysis of the reaction: benzo(a)pyrene + O2 = benzo(a)pyrene-cis-7,8-dihydrodiol.
34814	7,8-dihydroxy benzo(a)pyrene dioxygenase activity	F	Catalysis of the reaction: benzo(a)pyrene-cis-7,8-dihydrodiol + O2 = cis-4-(7-hydroxypyren-8-yl)-2-oxobut-3-enoate.
34815	cis-4-(8-hydroxypyren-7-yl)-2-oxobut-3-enoate lyase activity	F	Catalysis of the reaction: cis-4-(8-hydroxypyren-7-yl)-2-oxobut-3-enoate = 10-oxabenzo(def)chrysen-9-one + formate + H+.
34816	anthracene 9,10-dioxygenase activity	F	Catalysis of the reaction: anthracene + 2 H2O = cis-9,10-dihydroanthracene-9,10-diol.
34817	cis-9,10-dihydroanthracene-9,10-diol dehydrogenase activity	F	Catalysis of the reaction: cis-9,10-dihydroanthracene-9,10-diol = 9,10-anthraquinone + 4 H+ + 4 e-.
34818	ADD 9alpha-hydroxylase activity	F	Catalysis of the reaction: androsta-1,4-diene-3,17-dione + reduced ferredoxin + O2 = 3-hydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione + H2O + oxidized ferredoxin.
34819	3-HSA hydroxylase activity	F	Catalysis of the reaction: 3-hydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione + NADPH + H+ + O2 = 3,4-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione + NADP+ + H2O.
34820	4,9-DSHA hydrolase activity	F	Catalysis of the reaction: (3E,1Z)-4,5-9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate + H2O = (2E,4E)-2-hydroxyhexa-2,4-dienoate + 9,17-dioxo-1,2,3,4,10,19-hexanorandrostan-5-oate + H+.
34821	citronellol dehydrogenase activity	F	Catalysis of the reaction: citronellol + NAD+ = citronellal + NADH + H+.
34822	citronellal dehydrogenase activity	F	Catalysis of the reaction: citronellal + NAD+ + OH- = citronellate + NADH + H+.
34823	citronellyl-CoA ligase activity	F	Catalysis of the reaction: citronellate + CoASH + ATP = citronellyl-CoA + AMP + PPi.
34824	citronellyl-CoA dehydrogenase activity	F	Catalysis of the reaction: citronellyl-CoA + NAD+ = cis-geranyl-CoA + NADH + H+.
34825	tetralin ring-hydroxylating dioxygenase activity	F	Catalysis of the reaction: tetralin + O2 + NADH + H+ = cis-1,2-dihydroxy-1,2,5,6,7,8-hexahydronaphthalene + NAD+.
34826	1,2-dihydroxy-1,2,5,6,7,8-hexyhadronaphthalene dehydrogenase activity	F	Catalysis of the reaction: cis-1,2-dihydroxy-1,2,5,6,7,8-hexahydronaphthalene + NAD+ = 1,2-dihydroxy-5,6,7,8-tetrahydronaphthalene + NADH + H+.
34827	1,2-dihydroxy-5,6,7,8-tetrahydronaphthalene extradiol dioxygenase activity	F	Catalysis of the reaction: 1,2-dihydroxy-5,6,7,8-tetrahydronaphthalene + O2 = 4-(2-oxocyclohexyl)-2-hydroxy-buta-2,4-dienoate + H+.
34828	4-(2-oxocyclohexyl)-2-hydroxy-buta-2,4-dienoate hydrolase activity	F	Catalysis of the reaction: 4-(2-oxocyclohexyl)-2-hydroxy-buta-2,4-dienoate + H2O = 2-hydroxydec-2,4-diene-1,10-dioate + H+.
34829	2-hydroxydec-2,4-diene-1,10-dioate hydratase activity	F	Catalysis of the reaction: 2-hydroxydec-2,4-diene-1,10-dioate + H2O = (2Z)-2,4-dihydroxydec-2-enedioate.
34830	(2Z)-2,4-dihydroxydec-2-enedioate aldolase activity	F	Catalysis of the reaction: (2Z)-2,4-dihydroxydec-2-enedioate = pyruvate + 7-oxoheptanoate.
34831	(R)-(-)-1,2,3,4-tetrahydronaphthol dehydrogenase activity	F	Catalysis of the reaction: (R)-1,2,3,4-tetrahydronaphthol = 1,2,3,4-tetrahydronaphthalone + 2 H+ + 2 e-.
34832	geranial dehydrogenase activity	F	Catalysis of the reaction: geranial + NAD+ + OH- = geranylate + NADH + H+.
34833	geranylate CoA-transferase activity	F	Catalysis of the reaction: geranylate + CoASH = trans-geranyl-CoA + OH-.
34834	2-mercaptobenzothiazole dioxygenase activity	F	Catalysis of the reaction: 2-mercaptobenzothiazole + O2 + 2 H+ + 2 e- = 2-mercaptobenzothiazole-cis-6,7-dihydrodiol.
34835	2-mercaptobenzothiazole monooxygenase activity	F	Catalysis of the reaction: 2-mercaptobenzothiazole + 1/2 O2 = 6-hydroxy-2-mercaptobenzothiazole.
34836	6-hydroxy-2-mercaptobenzothiazole monooxygenase activity	F	Catalysis of the reaction: 6-hydroxy-2-mercaptobenzothiazole + 1/2 O2 = 6,7-dihydroxy-2-mercaptobenzothiazole.
34837	2-mercaptobenzothiazole-cis-6,7-dihydrodiol dehydrogenase activity	F	Catalysis of the reaction: 2-mercaptobenzothiazole-cis-6,7-dihydrodiol = 6,7-dihydroxy-2-mercaptobenzothiazole + 2 H+ + 2 e-.
34838	menthone dehydrogenase activity	F	Catalysis of the reaction: (-)-(2S,5R)-menthone + NAD+ = (5R)-menth-2-enone + NADH + H+.
34839	menth-2-enone hydratase activity	F	Catalysis of the reaction: (5R)-menth-2-enone + H2O = (5R)-3-hydroxymenthone.
34840	3-hydroxymenthone dehydrogenase activity	F	Catalysis of the reaction: (5R)-3-hydroxymenthone + NAD+ = mentha-1,3-dione + NADH + H+.
34841	mentha-1,3-dione-CoA ligase activity	F	Catalysis of the reaction: mentha-1,3-dione + CoASH = 3,7-dimethyl-5-oxo-octyl-CoA.
34842	thiophene-2-carboxylate-CoA ligase activity	F	Catalysis of the reaction: thiophene-2-carboxylate + ATP + CoASH = thiophene-2-carboxyl-CoA + AMP + PPi.
34843	2-oxoglutaryl-CoA thioesterase activity	F	Catalysis of the reaction: 2-oxoglutaryl-CoA + OH- = 2-oxoglutarate + CoASH.
34844	naphthyl-2-methyl-succinate CoA-transferase activity	F	Catalysis of the reaction: naphthyl-2-methyl-succinate + succinyl-CoA = naphthyl-2-methyl-succinyl-CoA + succinate.
34845	naphthyl-2-methyl-succinyl-CoA dehydrogenase activity	F	Catalysis of the reaction: naphthyl-2-methyl-succinyl-CoA = naphthyl-2-methylene-succinyl-CoA + 2 H+ + 2 e-.
34846	naphthyl-2-methylene-succinyl-CoA lyase activity	F	Catalysis of the reaction: naphthyl-2-methylene-succinyl-CoA + H2O = naphthyl-2-hydroxymethyl-succinyl-CoA.
34847	naphthyl-2-hydroxymethyl-succinyl-CoA dehydrogenase activity	F	Catalysis of the reaction: naphthyl-2-hydroxymethyl-succinyl-CoA = naphthyl-2-oxomethyl-succinyl-CoA + 2 H+ + 2 e-.
34848	naphthyl-2-oxomethyl-succinyl-CoA succinyl transferase activity	F	Catalysis of the reaction: naphthyl-2-oxomethyl-succinyl-CoA + CoASH = 2-naphthoyl-CoA + succinyl-CoA.
34849	2-naphthoate CoA-transferase activity	F	Catalysis of the reaction: 2-naphthoyl-CoA + OH- = 2-naphthoate + CoASH.
34850	isooctane monooxygenase activity	F	Catalysis of the reaction: isooctane + 1/2 O2 = 2,4,4-trimethyl-1-pentanol.
34851	2,4,4-trimethyl-3-oxopentanoyl-CoA 2-C-propanoyl transferase activity	F	Catalysis of the reaction: 2,4,4-trimethyl-3-oxopentanoyl-CoA + CoASH = pivalyl-CoA + propanoyl-CoA.
34852	4,4-dimethyl-3-oxopentanal dehydrogenase activity	F	Catalysis of the reaction: 4,4-dimethyl-3-oxopentanal + H2O = 4,4-dimethyl-3-oxopentanoate + 3 H+ + 2 e-.
34853	2,4,4-trimethyl-3-oxopentanoate decarboxylase activity	F	Catalysis of the reaction: 2,4,4-trimethyl-3-oxopentanoate + H+ = 2,2-dimethyl-3-pentanone + CO2.
34854	4,4-dimethyl-3-oxopentanoate decarboxylase activity	F	Catalysis of the reaction: 4,4-dimethyl-3-oxopentanoate + H+ = 3,3-dimethyl-2-butanone + CO2.
34855	4-AD 9alpha-hydroxylase activity	F	Catalysis of the reaction: androst-4-ene-3,17-dione + O2 + 2 H+ + 2 e- = 9alpha-hydroxy-4-androstene-3,17-dione + H2O.
34856	2-hydroxyhexa-2,4-dienoate hydratase activity	F	Catalysis of the reaction: (2E,4E)-2-hydroxyhexa-2,4-dienoate + H2O = 4-hydroxy-2-oxohexanoate.
34857	2-(methylthio)benzothiazole monooxygenase activity	F	Catalysis of the reaction: 2-(methylthio)benzothiazole + 1/2 O2 = 2-(methylsulfinyl)benzothiazole.
34858	2-hydroxybenzothiazole monooxygenase activity	F	Catalysis of the reaction: 2-hydroxybenzothiazole + 1/2 O2 = 2,6-dihydroxybenzothiazole.
34859	benzothiazole monooxygenase activity	F	Catalysis of the reaction: benzothiazole + 1/2 O2 = 2-hydroxybenzothiazole.
34860	2-mercaptobenzothiazole desulfurase activity	F	Catalysis of the reaction: 2-mercaptobenzothiazole + reduced acceptor = benzothiazole + hydrogen sulfide + oxidized acceptor.
34861	benzothiazole-2-sulfonate hydrolase activity	F	Catalysis of the reaction: benzothiazole-2-sulfonate + H2O = 2-hydroxybenzothiazole + HSO3-.
34862	2,6-dihydroxybenzothiazole monooxygenase activity	F	Catalysis of the reaction: 2,6-dihydroxybenzothiazole + 1/2 O2 = 2,6,7-trihydroxybenzothiazole.
34863	2,4,4-trimethyl-1-pentanol dehydrogenase activity	F	Catalysis of the reaction: 2,4,4-trimethyl-1-pentanol = 2,4,4-trimethylpentanal + 2 H+ + 2 e-.
34864	2,4,4-trimethylpentanal dehydrogenase activity	F	Catalysis of the reaction: 2,4,4-trimethylpentanal + H2O = 2,4,4-trimethylpentanoate + 3 H+ + 2 e-.
34865	2,4,4-trimethylpentanoate-CoA ligase activity	F	Catalysis of the reaction: 2,4,4-trimethylpentanoate + CoASH = 2,4,4-trimethylpentanoyl-CoA + OH-.
34866	2,4,4-trimethylpentanoyl-CoA dehydrogenase activity	F	Catalysis of the reaction: 2,4,4-trimethylpentanoyl-CoA = 2,4,4-trimethylpent-2-enoyl-CoA + 2 H+ + 2 e-.
34867	2,4,4-trimethylpent-2-enoyl-CoA hydratase activity	F	Catalysis of the reaction: 2,4,4-trimethylpent-2-enoyl-CoA + H2O = 2,4,4-trimethyl-3-hydroxypentanoyl-CoA.
34868	2,4,4-trimethyl-3-hydroxypentanoyl-CoA dehydrogenase activity	F	Catalysis of the reaction: 2,4,4-trimethyl-3-hydroxypentanoyl-CoA = 2,4,4-trimethyl-3-oxopentanoyl-CoA + 2 H+ + 2 e-.
34869	2,4,4-trimethyl-3-oxopentanoyl-CoA thioesterase activity	F	Catalysis of the reaction: 2,4,4-trimethyl-3-oxopentanoyl-CoA + OH- = 2,4,4-trimethyl-3-oxopentanoate + CoASH.
34870	pinacolone 5-monooxygenase activity	F	Catalysis of the reaction: 2,2-dimethyl-3-pentanone + 1/2 O2 = 1-hydroxy-4,4-dimethylpentan-3-one.
34871	1-hydroxy-4,4-dimethylpentan-3-one dehydrogenase activity	F	Catalysis of the reaction: 1-hydroxy-4,4-dimethylpentan-3-one = 4,4-dimethyl-3-oxopentanal + 2 H+ + 2 e-.
34872	trans-geranyl-CoA isomerase activity	F	Catalysis of the reaction: trans-geranyl-CoA = cis-geranyl-CoA.
34873	thioacetamide S-oxygenase activity	F	Catalysis of the reaction: thioacetamide + O2 + 2 H+ + 2 e- = thioacetamide S-oxide + H2O.
34874	thioacetamide S-oxide S-oxygenase activity	F	Catalysis of the reaction: thioacetamide S-oxide + O2 + 2 H+ + 2 e- = thioacetamide S,S-dioxide + H2O.
34875	caffeine oxidase activity	F	Catalysis of the reaction: caffeine + O2 + 2 H+ + 2 e- = 1,3,7-trimethyluric acid + H2O.
34876	isonicotinic acid hydrazide hydrolase activity	F	Catalysis of the reaction: isoniazid + H2O = isonicotinate + hydrazine.
34877	isonicotinate dehydrogenase activity	F	Catalysis of the reaction: isonicotinate + acceptor + H2O = 2-hydroxyisonicotinate + reduced acceptor.
34878	2-hydroxyisonicotinate dehydrogenase activity	F	Catalysis of the reaction: 2-hydroxyisonicotinate + acceptor + H2O = citrazinate + reduced acceptor.
34879	2,3,6-trihydroxyisonicotinate decarboxylase activity	F	Catalysis of the reaction: 2,3,6-trihydroxyisonicotinate = 2,3,6-trihydroxypyridine + CO2.
34880	citrazinate dehydrogenase activity	F	Catalysis of the reaction: citrazinate + H2O = 2,3,6-trihydroxyisonicotinate + 2 H+ + 2 e-.
34881	citrazinate hydrolase activity	F	Catalysis of the reaction: citrazinate + H2O = cis-aconitamide.
34882	cis-aconitamide amidase activity	F	Catalysis of the reaction: cis-aconitamide + H2O = cis-aconitate + HN3.
34885	gamma-N-formylaminovinylacetate hydrolase activity	F	Catalysis of the reaction: gamma-N-formylaminovinylacetate + H2O = gamma-aminovinylacetate + HCOOH.
34886	gamma-aminovinylacetate deaminase activity	F	Catalysis of the reaction: gamma-aminovinylacetate + H2O = succinic semialdehyde + NH3.
34888	endosulfan monooxygenase I activity	F	Catalysis of the reaction: endosulfan + O2 + 2 H+ + 2 e- = endosulfan sulfate + H2O.
34889	endosulfan hemisulfate sulfatase activity	F	Catalysis of the reaction: endosulfan hemisulfate + H2O = endosulfan monoalcohol + 2 H+ + sulfate.
34890	endosulfan diol hydrolyase (cyclizing) activity	F	Catalysis of the reaction: endosulfan diol = endosulfan ether + H2O.
34891	endosulfan diol dehydrogenase activity	F	Catalysis of the reaction: endosulfan diol = endosulfan hydroxyether + 2 H+ + 2 e-.
34892	endosulfan lactone lactonase activity	F	Catalysis of the reaction: endosulfan lactone + H2O = endosulfan hydroxycarboxylate + H+.
34893	N-nitrodimethylamine hydroxylase activity	F	Catalysis of the reaction: N-nitrodimethylamine + O2 + 2 H+ + 2 e- = N-nitromethylamine + formaldehyde + H2O.
34894	4-hydroxypyridine-3-hydroxylase activity	F	Catalysis of the reaction: 4-hydroxypyridine + O2 + H+ + NADPH = pyridine-3,4-diol + H2O + NADP+.
34895	pyridine-3,4-diol dioxygenase activity	F	Catalysis of the reaction: pryidine-3,4-diol + O2 = 3-(N-formyl)-formiminopyruvate.
34896	3-formiminopyruvate hydrolase activity	F	Catalysis of the reaction: 3-formiminopyruvate + H2O = 3-formylpyruvate + HN3.
34897	4-(1-ethyl-1,4-dimethyl-pentyl)phenol monoxygenase activity	F	Catalysis of the reaction: 4-(1-ethyl-1,4-dimethyl-pentyl)phenol + O2 + 2 H+ + 2 e- = hydroquinone + 3,6-dimethylheptan-3-ol.
34898	hexadecyltrimethylammonium chloride monooxygenase activity	F	Catalysis of the reaction: hexadecyltrimethylammonium chloride + NAD(P)H + H+ + O2 = trimethylamine + hexadecanal + NAD(P)+ + H2O.
34899	trimethylamine monooxygenase activity	F	Catalysis of the reaction: N,N,N-trimethylamine + NADPH + H+ + O2 = N,N,N-trimethylamine N-oxide + NADP+ + H2O.
34900	3-(N-formyl)-formiminopyruvate hydrolase activity	F	Catalysis of the reaction: 3-(N-formyl)-formiminopyruvate + H2O = 3-formiminopyruvate + formate.
34901	endosulfan hydroxyether dehydrogenase activity	F	Catalysis of the reaction: endosulfan hydroxyether = endosulfan lactone + 2 H+ + 2 e-.
34902	endosulfan sulfate hydrolase activity	F	Catalysis of the reaction: endosulfan sulfate + H2O = endosulfan diol + sulfite.
34903	endosulfan ether monooxygenase activity	F	Catalysis of the reaction: endosulfan ether + O2 + 2 H+ + 2 e- = endosulfan hydroxyether + H2O.
34904	5-chloro-2-oxopent-4-enoate hydratase activity	F	Catalysis of the reaction: 5-chloro-2-oxopent-4-enoate + H2O = 5-chloro-4-hydroxy-2-oxopentanate.
34905	5-chloro-4-hydroxy-2-oxopentanate aldolase activity	F	Catalysis of the reaction: 5-chloro-4-hydroxy-2-oxopentanate = pyruvate + chloroacetaldehyde.
34906	N-isopropylaniline 1,2-dixoxygenase activity	F	Catalysis of the reaction: N-isopropylaniline + O2 + 2 H+ + NADH = catechol + NAD+ + isopropylamine.
34907	acetanilide 1,2-dioxygenase activity	F	Catalysis of the reaction: acetanilide + O2 + 2 H+ + NADH = catechol + NAD+ + acetamide.
34908	2-chloro-N-isopropylacetanilide 1,2-dioxygenase activity	F	Catalysis of the reaction: 2-chloro-N-isopropylacetanilide + O2 + 2 H+ + NADH = 2-chloro-N-isopropylacetamide + catechol + NAD+.
34909	6-hydroxypseudooxynicotine dehydrogenase activity	F	Catalysis of the reaction: 6-hydroxypseudooxynicotine + H2O + OH- = 6-hydroxy-3-succinoylpyridine + 4 H+ + 4 e- + methylamine.
34910	6-hydroxy-3-succinoylpyridine hydrolase activity	F	Catalysis of the reaction: 6-hydroxy-3-succinoylpyridine + H2O = succinic semialdehyde + 2,5-dihydroxypyridine.
34911	phthalate 3,4-dioxygenase activity	F	Catalysis of the reaction: phthalate + O2 + NADH + H+ = phthalate 3,4-cis-dihydrodiol + NAD+.
34912	phthalate 3,4-cis-dihydrodiol dehydrogenase activity	F	Catalysis of the reaction: phthalate 3,4-cis-dihydrodiol + NAD+ = 3,4-dihydroxyphthalate + NADH + H+.
34914	trinitrophenol hydride denitratase activity	F	Catalysis of the reaction: trinitrophenol hydride Meisenheimer complex = 2,4-dinitrophenol + nitrite. Trinitrophenol is also known as TNP.
34915	2-methylhexanoyl-CoA C-acetyltransferase activity	F	Catalysis of the reaction: 4-methyl-3-oxooctanoyl-CoA + CoA = acetyl-CoA + 2-methylhexanoyl-CoA.
34916	2-methylhexanoyl-CoA dehydrogenase activity	F	Catalysis of the reaction: 2-methylhexanoyl-CoA = 2-methylhex-2-enoyl-CoA + 2 H+ + e-.
34917	2-methylhex-2-enoyl-CoA hydratase activity	F	Catalysis of the reaction: 2-methylhex-2-enoyl-CoA + H2O = 3-hydroxy-2-methylhexanoyl-CoA.
34918	3-hydroxy-2-methylhexanoyl-CoA dehydrogenase activity	F	Catalysis of the reaction: 3-hydroxy-2-methylhexanoyl-CoA = 2-methyl-3-oxohexanoyl-CoA + 2 H+ + 2 e-.
34919	butyryl-CoA 2-C-propionyltransferase activity	F	Catalysis of the reaction: 2-methyl-3-oxohexanoyl-CoA + CoA = propanoyl-CoA + butyryl-CoA.
34920	pyrene dioxygenase activity	F	Catalysis of the reaction: pyrene + 2 H+ + 2 e- + O2 = cis-4,5-dihydroxy-4,5-dihydropyrene.
34921	cis-4,5-dihydroxy-4,5-dihydropyrene dehydrogenase activity	F	Catalysis of the reaction: cis-4,5-dihydroxy-4,5-dihydropyrene = 4,5-dihydroxypyrene + 2 H+ + 2 e-.
34922	4,5-dihydroxypyrene dioxygenase activity	F	Catalysis of the reaction: 4,5-dihydroxypyrene + O2 = phenanthrene-4,5-dicarboxylate + 2 H+.
34923	phenanthrene-4,5-dicarboxylate decarboxylase activity	F	Catalysis of the reaction: phenanthrene-4,5-dicarboxylate + H+ = phenanthrene-4-carboxylate + CO2.
34924	cis-3,4-phenanthrenedihydrodiol-4-carboxylate dehydrogenase activity	F	Catalysis of the reaction: cis-3,4-phenanthrenedihydrodiol-4-carboxylate = 3,4-dihydroxyphenanthrene + H+ + 2 e- + CO2.
34925	pyrene 4,5-monooxygenase activity	F	Catalysis of the reaction: pyrene + O2 + 2 H+ + 2 e- = pyrene-4,5-oxide + H2O.
34926	pyrene-4,5-epoxide hydrolase activity	F	Catalysis of the reaction: pyrene-4,5-oxide + H2O = trans-4,5-dihydroxy-4,5-dihydropyrene.
34927	pyrene 1,2-monooxygenase activity	F	Catalysis of the reaction: pyrene + O2 + 2 H+ + 2 e- = pyrene-1,2-oxide + H2O.
34928	1-hydroxypyrene 6,7-monooxygenase activity	F	Catalysis of the reaction: 1-hydroxypyrene + O2 + 2 H+ + 2 e- = 1-hydroxypyrene-6,7-oxide + H2O.
34929	1-hydroxypyrene 7,8-monooxygenase activity	F	Catalysis of the reaction: 1-hydroxypyrene + O2 + 2 H+ + 2 e- = 1-hydroxypyrene-7,8-oxide + H2O.
34930	1-hydroxypyrene sulfotransferase activity	F	Catalysis of the reaction: 1-hydroxypyrene + XSO3- = 1-pyrenylsulfate + HX.
34931	1-hydroxypyrene methyltransferase activity	F	Catalysis of the reaction: 1-hydroxypyrene + XCH3 = 1-methoxypyrene + HX.
34932	1-methoxypyrene 6,7-monooxygenase activity	F	Catalysis of the reaction: 1-methoxypyrene + O2 + 2 H+ + 2 e- = 1-methoxypyrene-6,7-oxide + H2O.
34933	1-hydroxy-6-methoxypyrene methyltransferase activity	F	Catalysis of the reaction: 1-hydroxy-6-methoxypyrene + XCH3 = 1,6-dimethoxypyrene + HX.
34934	phenanthrene-4-carboxylate dioxygenase activity	F	Catalysis of the reaction: phenanthrene-4-carboxylate + 2 H+ + 2 e- + O2 = cis-3,4-phenanthrenedihydrodiol-4-carboxylate.
34935	tetrachlorobenzene dioxygenase activity	F	Catalysis of the reaction: 2,4-dichlorotoluene + NADH + H+ + O2 = 4,6-dichloro-3-methyl-cis-1,2-dihydroxycyclohexa-3,5-diene + NAD+.
34936	4,6-dichloro-3-methylcatechol 1,2-dioxygenase activity	F	Catalysis of the reaction: 4,6-dichloro-3-methylcatechol + O2 = 3,5-dichloro-3-methyl-cis,cis-muconate + 2 H+.
34937	perchlorate reductase activity	F	Catalysis of the reaction: perchlorate + 2 H+ + 2 e- = chlorate + H2O.
34938	pyrrole-2-carboxylate monooxygenase activity	F	Catalysis of the reaction: pryrole-2-carboxylate + NADH + O2 + H+ = 5-hydroxypyrrole-2-carboxylate + NAD+ + H2O.
34939	5-hydroxypyrrole-2-carboxylate tautomerase activity	F	Catalysis of the reaction: 5-hydroxypyrrole-2-carboxylate = 5-oxo-4,5-dihydropyrrole-2-carboxylate.
34940	5-oxo-4,5-dihydropyrrole-2-carboxylate amidase activity	F	Catalysis of the reaction: 5-oxo-4,5-dihydropyrrole-2-carboxylate + 2 H2O = 2-oxoglutarate + NH3.
34941	pyrrole-2-carboxylate decarboxylase activity	F	Catalysis of the reaction: pryrole-2-carboxylate + H+ = pyrrole + CO2.
34942	cis-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity	F	Catalysis of the reaction: cis-2-methyl-5-isopropylhexa-2,5-dienoic acid + ATP + CoASH = cis-2-methyl-5-isopropylhexa-2,5-dienoyl-CoA + AMP + PPi.
34943	trans-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity	F	Catalysis of the reaction: trans-2-methyl-5-isopropylhexa-2,5-dienoic acid + ATP + CoASH = trans-2-methyl-5-isopropylhexa-2,5-dienoyl-CoA + AMP + PPi.
34944	3-hydroxy-2,6-dimethyl-5-methylene-heptanoyl-CoA dehydrogenase activity	F	Catalysis of the reaction: 3-hydroxy-2,6-dimethyl-5-methylene-heptanoyl-CoA + NAD+ = 2,6-dimethyl-5-methylene-3-oxo-heptanoyl-CoA + NADH+ + H+.
34945	2,6-dimethyl-5-methylene-3-oxo-heptanoyl-CoA C-acetyltransferase activity	F	Catalysis of the reaction: 2,6-dimethyl-5-methylene-3-oxo-heptanoyl-CoA + CoASH = 3-isopropylbut-3-enoyl-CoA + propanoyl-CoA.
34946	3-isopropylbut-3-enoyl-CoA thioesterase activity	F	Catalysis of the reaction: 3-isopropylbut-3-enoyl-CoA + H2O = 3-isopropylbut-3-enoic acid + CoASH.
34947	terephthalate decarboxylase activity	F	Catalysis of the reaction: terephthalate + H2O = benzoate + HCO3-.
34948	2,6-dihydroxypseudooxynicotine hydrolase activity	F	Catalysis of the reaction: 2,6-dihydroxypseudooxynicotine + H2O = 2,6-dihydroxypyridine + 4-methylaminobutyrate.
34949	1,1-dichloroethane reductive dehalogenase activity	F	Catalysis of the reaction: 1,1-dichloroethane + 2 H+ + 2 e- = chloroethane + HCl.
34950	phenylboronic acid monooxygenase activity	F	Catalysis of the reaction: phenylboronic acid + O2 + 2 H+ + 2 e- = phenol + B(OH)3.
34951	o-hydroxylaminobenzoate mutase activity	F	Catalysis of the reaction: o-hydroxylaminobenzoate = 3-hydroxyanthranilate.
34952	malonate semialdehyde decarboxylase activity	F	Catalysis of the reaction: malonate semialdehyde + H+ = acetaldehyde + CO2.
34953	perillyl-CoA hydratase activity	F	Catalysis of the reaction: perillyl-CoA + H2O = 2-hydroxy-4-isopropenylcyclohexane-1-carboxyl-CoA.
34954	diphenyl ether 2,3-dioxygenase activity	F	Catalysis of the reaction: diphenyl ether + O2 = 2,3-dihydroxydiphenyl ether.
34955	2,3-dihydroxydiphenyl ether dioxygenase activity	F	Catalysis of the reaction: 2,3-dihydroxydiphenyl ether + O2 + H2O = 2-hydroxymuconate + phenol.
34956	diphenyl ether 1,2-dioxygenase activity	F	Catalysis of the reaction: diphenyl ether + NADH + O2 + H+ = phenol + catechol + NAD+.
34957	3-nitrophenol nitroreductase activity	F	Catalysis of the reaction: 3-nitrophenol + 2 NADH + 2 H+ = 3-hydroxyaminophenol + 2 NAD+ + H2O.
34958	aminohydroquinone monooxygenase activity	F	Catalysis of the reaction: aminohydroquinone + 2 e- + 2 H+ + 1/2 O2 = 1,2,4-benzenetriol + NH3.
34959	endothelin maturation	P	The process leading to the attainment of the full functional capacity of endothelin by conversion of Big-endothelin substrate into mature endothelin.
34963	box C/D snoRNA processing	P	Any process involved in the conversion of a primary box C/D type small nucleolar RNA (snoRNA) transcript into a mature box C/D snoRNA.
34964	box H/ACA snoRNA processing	P	Any process involved in the conversion of a primary box H/ACA type small nucleolar RNA (snoRNA) transcript into a mature box H/ACA snoRNA.
34965	intronic box C/D snoRNA processing	P	Any process involved in the conversion of a primary box C/D type small nucleolar RNA (snoRNA) transcript that resides within, and is processed from, the intron of a pre-mRNA into a mature box C/D snoRNA.
34966	intronic box H/ACA snoRNA processing	P	Any process involved in the conversion of a primary box H/ACA type small nucleolar RNA (snoRNA) transcript that resides within, and is processed from, the intron of a pre-mRNA into a mature box H/ACA snoRNA.
34967	Set3 complex	C	A histone deacetylase complex that is involved in transcriptional regulation. In S. cerevisiae, this complex consists of Set3p, Snt1p, Hos4p, Sif2p, Cpr1p, Hos2p, and Hst1p.
34968	histone lysine methylation	P	The modification of a histone by addition of one or more methyl groups to a lysine residue.
34969	histone arginine methylation	P	The modification of a histone by addition of a methyl group to an arginine residue.
34970	histone H3-R2 methylation	P	The modification of histone H3 by addition of a methyl group to arginine at position 2 of the histone.
34971	histone H3-R17 methylation	P	The modification of histone H3 by addition of a methyl group to arginine at position 17 of the histone.
34972	histone H3-R26 methylation	P	The modification of histone H3 by addition of a methyl group to arginine at position 26 of the histone.
34973	Sid2-Mob1 complex	C	A protein complex that contains a protein kinase (Sid2 in S. pombe) and its regulatory subunit (Mob1). The Sid2p-Mob1p kinase complex is a component of the septation initiation network in fission yeast (called the mitotic exit network in S. cerevisiae) and is required for cytokinesis. The analogous complex in S. cerevisiae is called Dbf2p-Mob1p complex.
34974	Swi5-Swi2 complex	C	A protein complex involved that contains proteins known in Schizosaccharomyces as Swi5 monomers and Swi2, and is involved in mating type switching.
34975	protein folding in endoplasmic reticulum	P	A protein folding process that takes place in the endoplasmic reticulum (ER). Secreted, plasma membrane and organelle proteins are folded in the ER, assisted by chaperones and foldases (protein disulphide isomerases), and additional factors required for optimal folding (ATP, Ca2+ and an oxidizing environment to allow disulfide bond formation).
34976	response to endoplasmic reticulum stress	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stress acting at the endoplasmic reticulum. ER stress usually results from the accumulation of unfolded or misfolded proteins in the ER lumen.
34977	ABIN2-NFKB1-MAP3K8 complex	C	A protein complex that contains the precursor form of NF-kappaB (p105), the NF-kappaB inhibitor ABIN-2, and the kinase TPL-2 (MAP3K8); the complex stabilizes TPL-2 and is involved in signaling in lipopolysaccharide (LPS)-stimulated macrophages.
34978	PDX1-PBX1b-MRG1 complex	C	A protein complex that contains the homeodomain proteins PDX1, PBX1b and MRG1 (MEIS2) and is involved in the transcriptional regulation of pancreatic acinar cell-specific genes.
34979	NAD-dependent protein deacetylase activity	F	Catalysis of the removal of one or more acetyl groups from a protein, requiring NAD.
34980	FHL2-CREB complex	C	A protein complex that contains CREB and FHL2, and is involved in transcriptional regulation.
34981	FHL3-CREB complex	C	A protein complex that contains CREB and FHL3, and is involved in transcriptional regulation.
34982	mitochondrial protein processing	P	The peptide cleavage of mitochondrial proteins, including cleavage contributing to their import.
34983	peptidyl-lysine deacetylation	P	The removal of an acetyl group from an acetylated lysine residue in a peptide or protein.
34985	Ecsit-NDUFAF1 complex	C	Any large protein complex that contains Ecsit and NDUFAF1, is located in the mitochondrion, and is involved in the assembly of complex I of the oxidative phosphorylation system. In mammalian cells, three complexes of approximately 500, 600, and 850 kDa containing the 45 kDa isoform of Ecsit and NDUFAF1 have been observed.
34986	iron chaperone activity	F	Assists in the delivery of iron ions to target proteins or compartments.
34987	immunoglobulin receptor binding	F	Interacting selectively and non-covalently with one or more specific sites on an immunoglobulin receptor molecule.
34988	Fc-gamma receptor I complex binding	F	Interacting selectively and non-covalently with one or more specific sites on the Fc-gamma receptor I complex. The complex functions primarily as an activating receptor for IgG.
34990	nuclear mitotic cohesin complex	C	A cohesin complex that mediates sister chromatid cohesion in the nucleus during mitosis; has a subunit composition distinct from that of the meiotic cohesin complex.
34991	nuclear meiotic cohesin complex	C	A cohesin complex that mediates sister chromatid cohesion in the nucleus during meiosis; has a subunit composition distinct from that of the mitotic cohesin complex.
34992	microtubule organizing center attachment site	C	A region of the nuclear envelope to which a microtubule organizing center (MTOC) attaches; protein complexes embedded in the nuclear envelope mediate direct or indirect linkages between the microtubule cytoskeleton and the nuclear envelope.
34993	LINC complex	C	A protein complex that spans the nuclear outer and inner membranes, thereby linking the major cytoplasmic cytoskeleton elements to the nuclear lumen; the complex is conserved in eukaryotes and contains proteins with SUN and KASH domains.
34994	microtubule organizing center attachment site organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a microtubule organizing center attachment site. A microtubule organizing center attachment site is a region of the nuclear envelope to which a microtubule organizing center (MTOC) attaches.
34995	SC5b-7 complex	C	A protein complex that consist of complement components C5b6 and C7 stably inserted in a cell membrane. Formation of the SC5b-7 complex is the first phase of membrane attack complex assembly.
34996	RasGAP-Fyn-Lyn-Yes complex	C	A protein complex that consists of a GTPase activator protein (GAP) for Ras and three Src family protein tyrosine kinases, Fyn, Lyn and Yes. The complex is involved in signaling upon platelet activation.
34997	alphav-beta5 integrin-vitronectin complex	C	A protein complex that comprises one integrin alphav subunit, one integrin beta5 subunit, and vitronectin.
34998	oligosaccharyltransferase I complex	C	An oligosaccharyltransferase (OST) complex that contains at least seven polypeptides and is the major OST complex in mammalian cells. Of the three forms of mammalian OST complex identified, the OSTI complex has the weakest affinity for ribosomes.
34999	oligosaccharyltransferase II complex	C	An oligosaccharyltransferase (OST) complex that contains the seven polypeptides found in OST complex I, plus heterotrimeric Sec61alpha-beta-gamma. Of the three forms of mammalian OST complexes identified, the OSTII complex has intermediate affinity for ribosomes.
35000	oligosaccharyltransferase III complex	C	An oligosaccharyltransferase (OST) complex that contains the seven polypeptides found in OST complex I, plus heterotrimeric Sec61alpha-beta-gamma and the tetrameric TRAP complex. Of the three forms of mammalian OST complexes identified, the OSTIII complex has the strongest affinity for ribosomes.
35001	dorsal trunk growth, open tracheal system	P	Growth of epithelial tubes that originate from pits in an open tracheal system and grow towards each other to meet and form a continuous open tube called the dorsal trunk. The dorsal trunk extends from the anterior spiracle to the posterior spiracle of the larva and forms the main airway of the insect tracheal system.
35002	liquid clearance, open tracheal system	P	The clearance of liquid from the epithelial tubes of an open tracheal system, shortly before the emergence of the larva, to generate an air-filled tubule system.
35003	subapical complex	C	The most apical region of the lateral plasma membrane of an invertebrate epithelial cell. The subapical complex lies above the zonula adherens and the septate junction, and is comparable to the position of the tight junction of vertebrate cells.
35004	phosphatidylinositol 3-kinase activity	F	Catalysis of the reaction: ATP + a phosphatidylinositol = ADP + a phosphatidylinositol 3-phosphate. This reaction is the addition of a phosphate group to phosphatidylinositol or one of its phosphorylated derivatives at the 3' position of the inositol ring.
35005	1-phosphatidylinositol-4-phosphate 3-kinase activity	F	Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 4-phosphate + ATP = 1-phosphatidyl-1D-myo-inositol 3,4-bisphosphate + ADP + 2 H(+).
35006	melanization defense response	P	The blackening of the wounded area of the cuticle or the surface of invading pathogens, parasites or parasitoids, resulting from a proteolytic cascade leading to the de novo synthesis and deposition of melanin.
35007	regulation of melanization defense response	P	Any process that affects the rate, extent or location of the melanization defense response during injury or invasion.
35008	positive regulation of melanization defense response	P	Any process that increases the rate or extent of the melanization defense response during injury or invasion.
35009	negative regulation of melanization defense response	P	Any process that reduces the rate or extent of the melanization defense response. This regulation is critical to limit melanization to the site of injury or infection.
35010	encapsulation of foreign target	P	Events resulting in the formation of a multilayered cellular sheath surrounding an invader and thus preventing its development. This defense mechanism is often seen in insects in response to nematodes or parasitoids, which are too large to be phagocytosed by individual hemocytes. In some organisms the capsule is blackened due to melanization.
35011	melanotic encapsulation of foreign target	P	Formation of a multilayered, melanized sheath of cells around a foreign invader.
35012	polytene chromosome, telomeric region	C	The terminal region of a polytene chromosome.
35013	myosuppressin receptor activity	F	Combining with the peptide myosuppressin to initiate a change in cell activity.
35014	phosphatidylinositol 3-kinase regulator activity	F	Modulates the activity of any of the phosphatidylinositol 3-kinases (PI3Ks). Regulatory subunits can link a PI3K catalytic subunit to upstream signaling events and help position the catalytic subunits close to their lipid substrates.
35015	elongation of arista core	P	The increase in length of the aristal core. The arista is the terminal segment of the antenna and consists of a central core and a series of lateral extensions.
35016	elongation of arista lateral	P	The increase in length of the aristal laterals. The arista is the terminal segment of the antenna and consists of a central core and a series of lateral extensions.
35017	cuticle pattern formation	P	The regionalization process that gives rise to the patterns of cell differentiation in the cuticle.
35018	adult chitin-based cuticle pattern formation	P	The process that gives rise to the patterns of cell differentiation that will arise in the chitin-based adult cuticle. An example of this process is adult chitin-based cuticle pattern formation in Drosophila melanogaster.
35019	somatic stem cell population maintenance	P	Any process by which an organism retains a population of somatic stem cells, undifferentiated cells in the embryo or adult which can undergo unlimited division and give rise to cell types of the body other than those of the germ-line.
35020	regulation of Rac protein signal transduction	P	Any process that modulates the frequency, rate or extent of Rac protein signal transduction.
35021	negative regulation of Rac protein signal transduction	P	Any process that stops, prevents, or reduces the frequency, rate or extent of Rac protein signal transduction.
35022	positive regulation of Rac protein signal transduction	P	Any process that activates or increases the frequency, rate or extent of Rac protein signal transduction.
35023	regulation of Rho protein signal transduction	P	Any process that modulates the frequency, rate or extent of Rho protein signal transduction.
35024	negative regulation of Rho protein signal transduction	P	Any process that stops, prevents, or reduces the frequency, rate or extent of Rho protein signal transduction.
35025	positive regulation of Rho protein signal transduction	P	Any process that activates or increases the frequency, rate or extent of Rho protein signal transduction.
35026	leading edge cell differentiation	P	The process in which relatively unspecialized cells acquire specialized structural and/or functional features of leading edge cells, cells at the front of a migrating epithelial sheet.
35027	leading edge cell fate commitment	P	The commitment of cells to leading edge cell fate and their capacity to differentiate into leading edge cells. Leading edge cells are found at the front of a migrating epithelial sheet.
35028	leading edge cell fate determination	P	The process in which a cell becomes capable of differentiating autonomously into a leading edge cell regardless of its environment; upon determination, the cell fate cannot be reversed.
35029	dorsal closure, leading edge cell fate commitment	P	The commitment of cells to leading edge cell fate during dorsal closure. Leading edge cells are the dorsal-most cells of the migrating epidermis.
35032	phosphatidylinositol 3-kinase complex, class III	C	A phosphatidylinositol 3-kinase complex that contains a catalytic class III phosphoinositide 3-kinase (PI3K) subunit bound to a regulatory (adaptor) subunit. Additional adaptor proteins may be present. Class III PI3Ks have a substrate specificity restricted to phosphatidylinositol (PI).
35033	histone deacetylase regulator activity	F	Modulates the activity of histone deacetylase.
35034	histone acetyltransferase regulator activity	F	Modulates the activity of histone acetyltransferase.
35035	histone acetyltransferase binding	F	Interacting selectively and non-covalently with the enzyme histone acetyltransferase.
35036	sperm-egg recognition	P	The initial contact step made between the sperm plasma membrane and outer layer of the egg during fertilization.
35037	sperm entry	P	An endocytosis process that results in penetration of the egg shell through the micropyle (a specialized anterior opening in the vitelline envelope) and entry of the entire sperm, including the surrounding plasma membrane and the sperm tail, into the egg cytoplasm. This step in fertilization is seen in Drosophila, where a plasma membrane fusion event between the sperm and the egg does not occur.
35038	female pronucleus assembly	P	Assembly of the haploid nucleus of the unfertilized egg.
35039	male pronucleus assembly	P	The conversion at fertilization of the inactive sperm nucleus into a male pronucleus with its chromosomes processed for the first zygotic division.
35040	sperm nuclear envelope removal	P	Removal of the sperm nuclear envelope, allowing entry of maternal factors into the sperm nucleus.
35041	sperm chromatin decondensation	P	Unwinding of the condensed nuclear chromatin of an inactive sperm nucleus.
35042	fertilization, exchange of chromosomal proteins	P	Replacement of sperm-specific chromosomal proteins with somatic histones, to allow the paternal genome to acquire a nucleosomal chromatin organization compatible with nuclear activity.
35043	male pronuclear envelope synthesis	P	Assembly of a nuclear envelope containing nuclear pores and a lamina around the male pronucleus, the final step in sperm pronuclear formation.
35044	sperm aster formation	P	Formation and organization of an aster composed of microtubule arrays originating from the sperm basal body and extending virtually to the egg periphery. The sperm aster ensures the appropriate positioning of the male and female pronuclei.
35045	sperm plasma membrane disassembly	P	The gradual disintegration of the sperm plasma membrane following insemination. This process is seen in Drosophila after entry of the entire sperm, surrounded by its plasma membrane, into the egg.
35046	pronuclear migration	P	The directed movement of the male and female pronuclei towards each other prior to their fusion.
35047	centrosomal and pronuclear rotation	P	The rotation of centrosomes and associated pronuclei in one-cell embryos such as those of Caenorhabditis elegans, occurring as a transition between pronuclear migration and pronuclear fusion.
35048	splicing factor protein import into nucleus	P	The directed movement of a pre-mRNA splicing factor from the cytoplasm into the nucleus, across the nuclear membrane.
35049	juvenile hormone acid methyltransferase activity	F	Catalysis of the transfer of a methyl group to juvenile hormone acid.
35050	embryonic heart tube development	P	The process whose specific outcome is the progression of the embryonic heart tube over time, from its formation to the mature structure. The heart tube forms as the heart rudiment from the heart field.
35051	cardiocyte differentiation	P	The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cell that will form part of the cardiac organ of an individual.
35052	dorsal vessel aortic cell fate commitment	P	The commitment of dorsal vessel cardioblast cells to an aortic cell fate and their capacity to differentiate into aortic cells. An example of this process is found in Drosophila melanogaster.
35053	dorsal vessel heart proper cell fate commitment	P	The commitment of dorsal vessel cardioblast cells to a heart proper cell fate and their capacity to differentiate into heart cells. An example of this process is found in Drosophila melanogaster.
35054	embryonic heart tube anterior/posterior pattern specification	P	The establishment, maintenance and elaboration of cell differentiation that results in the anterior/posterior subdivision of the embryonic heart tube. In Drosophila this results in subdivision of the dorsal vessel into to the posterior heart proper and the anterior aorta.
35059	RCAF complex	C	A protein complex that facilitates the assembly of nucleosomes on to newly synthesized DNA. In Drosophila, the complex comprises ASF1 and histones H3 and H4.
35060	brahma complex	C	A SWI/SNF-type complex that contains the ATPase product of the Drosophila brahma gene, or an ortholog thereof.
35061	interchromatin granule	C	A class of nuclear body measuring 20-25 nm in diameter and distributed throughout the interchromatin space, linked together by thin fibrils. They are believed to be storage centers for various snRNAs, snRNPs, serine/arginine-rich proteins and RNA polymerase II. A typical mammalian cell contains 25-50 clusters of interchromatin granules. Interchromatin granule clusters do not contain the heterogeneous nuclear RNA-binding proteins (hnRNPs).
35062	omega speckle	C	A nucleoplasmic speckle distributed in the interchromatin space of cells in close proximity to chromatin. Omega speckles are distinct from interchromatin granules and contain heterogeneous nuclear RNA-binding proteins (hnRNPs).
35063	nuclear speck organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of nuclear specks, a class of nuclear body in which splicing factors are localized.
35064	methylated histone binding	F	Interacting selectively and non-covalently with a histone protein in which a residue has been modified by methylation. Histones are any of a group of water-soluble proteins found in association with the DNA of plant and animal chromosomes.
35065	regulation of histone acetylation	P	Any process that modulates the frequency, rate or extent of the addition of an acetyl group to a histone protein.
35066	positive regulation of histone acetylation	P	Any process that activates or increases the frequency, rate or extent of the addition of an acetyl group to a histone protein.
35067	negative regulation of histone acetylation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the addition of an acetyl group to a histone protein.
35068	micro-ribonucleoprotein complex	C	A complex containing both protein and micro-RNA (miRNA) molecules. miRNAs are approximately 22 nucleotide noncoding RNAs derived from endogenous genes; they are processed from the stem of a longer hairpin like structure termed a pre-miRNA.
35069	larval midgut histolysis	P	The stage-specific break down of the larval midgut during Drosophila metamorphosis, to allow replacement of larval structures by tissues and structures that form the adult fly.
35070	salivary gland histolysis	P	The stage-specific break down of the larval salivary glands during Drosophila metamorphosis, to allow replacement of larval structures by tissues and structures that form the adult fly.
35071	salivary gland cell autophagic cell death	P	The stage-specific programmed cell death of salivary gland cells during salivary gland histolysis.
35072	ecdysone-mediated induction of salivary gland cell autophagic cell death	P	Any process induced by ecdysone that directly activates salivary gland programmed cell death during salivary gland histolysis.
35073	pupariation	P	The onset of prepupal development when the larval stops crawling, everts its spiracles and the larval cuticle becomes the puparium or pupal case that surrounds the organism for the duration of metamorphosis.
35074	pupation	P	The act of becoming a pupa, a resting stage in the life cycle of organisms with complete metamorphosis. This event marks the end of the prepupal period and the beginning of the pupal period.
35075	response to ecdysone	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ecdysone stimulus.
35076	ecdysone receptor-mediated signaling pathway	P	The series of molecular signals generated by ecdysone binding to the ecdysone receptor complex.
35077	ecdysone-mediated polytene chromosome puffing	P	The decondensing (loosening) and swelling of the chromosomal sites of hormone-responsive genes on polytene chromosomes in response to increased production of the steroid hormone 20-hydroxyecdysone (ecdysone) in Drosophila larvae approaching pupation.
35078	induction of programmed cell death by ecdysone	P	Any process induced by the steroid hormone 20-hydroxyecdysone (ecdysone) that directly activates any of the steps required for programmed cell death.
35079	polytene chromosome puffing	P	The decondensing (loosening) and swelling of the chromosomal sites of target genes on polytene chromosomes following response to a stimulus, to facilitate sudden bursts of transcriptional activity in response to transient environmental signals.
35080	heat shock-mediated polytene chromosome puffing	P	The decondensing (loosening) and swelling of the chromosomal sites of heat shock genes on polytene chromosomes in response to a heat shock stimulus.
35081	induction of programmed cell death by hormones	P	Any process induced by hormones that directly activates any of the steps required for programmed cell death.
35082	axoneme assembly	P	The assembly and organization of an axoneme, the bundle of microtubules and associated proteins that forms the core of cilia (also called flagella) in eukaryotic cells and is responsible for their movements.
35087	siRNA loading onto RISC involved in RNA interference	P	The transfer of small interfering RNA molecules (siRNAs) from the Dicer family of enzymes that cleave the double-stranded RNA, onto the nuclease-containing RNA-initiated silencing complex (RISC), in the context of RNA interference.
35088	establishment or maintenance of apical/basal cell polarity	P	Any cellular process that results in the specification, formation or maintenance polarization of a cell's architecture along its apical/basal axis so that the apical and basal regions of the cell have different membrane, extracellular matrix and sub-membrane cellular components.
35089	establishment of apical/basal cell polarity	P	The specification and formation of the polarity of a cell along its apical/basal axis.
35090	maintenance of apical/basal cell polarity	P	Retaining the established polarization of a cell along its apical/basal axis.
35091	phosphatidylinositol binding	F	Interacting selectively and non-covalently with any inositol-containing glycerophospholipid, i.e. phosphatidylinositol (PtdIns) and its phosphorylated derivatives.
35092	sperm chromatin condensation	P	The progressive compaction of the spermatid chromatin so that it reaches a level of condensation that is not compatible with nuclear activities such as transcription or DNA replication.
35093	spermatogenesis, exchange of chromosomal proteins	P	The replacement of somatic histones within sperm chromatin with sperm-specific histones or protamines with unique DNA-binding properties, resulting in condensation of the sperm chromatin.
35094	response to nicotine	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nicotine stimulus.
35095	behavioral response to nicotine	P	Any process that results in a change in the behavior of an organism as a result of a nicotine stimulus.
35096	larval midgut cell programmed cell death	P	The stage-specific programmed cell death of cells of the larval midgut, during histolysis of the larval organ.
35097	histone methyltransferase complex	C	A multimeric complex that is able to catalyze the addition of methyl groups to histone proteins.
35098	ESC/E(Z) complex	C	A multimeric protein complex that can methylate lysine-27 and lysine-9 residues of histone H3. In Drosophila the core subunits of the complex include ESC, E(Z), CAF1 (NURF-55) and SU(Z)12. In mammals the core subunits of the complex include EED, EZH2, SUZ12 and RBBP4.
35099	hemocyte migration	P	The directed movement of a hemocyte within the embryo. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen. In Drosophila, embryonic hemocytes originate from the head mesoderm as a cluster of cells. The cluster splits into two and one group of cells crosses the amnioserosa. Both populations then spread toward the middle of the embryo and then disperse evenly throughout the embryo.
35100	ecdysone binding	F	Interacting selectively and non-covalently with 20-hydroxyecdysone (ecdysone). Ecdysone is an ecdysteroid produced by the prothoracic glands of immature insects and the ovaries of adult females, which stimulates growth and molting.
35101	FACT complex	C	An abundant nuclear complex, which was originally identified in mammalian systems as a factor required for transcription elongation on chromatin templates. The FACT complex has been shown to destablilize the interaction between the H2A/H2B dimer and the H3/H4 tetramer of the nucleosome, thus reorganizing the structure of the nucleosome. In this way, the FACT complex may play a role in DNA replication and other processes that traverse the chromatin, as well as in transcription elongation. FACT is composed of two proteins that are evolutionarily conserved in all eukaryotes and homologous to mammalian Spt16 and SSRP1. In metazoans, the SSRP1 homolog contains an HMG domain; however in fungi and protists, it does not. For example, in S. cerevisiae the Pob3 protein is homologous to SSRP1, but lacks the HMG chromatin binding domain. Instead, the yFACT complex of Spt16p and Pob3p, binds to nucleosomes where multiple copies of the HMG-domain containing protein Nhp6p have already bound, but Nhp6p does not form a stable complex with the Spt16p/Pob3p heterodimer.
35102	PRC1 complex	C	A multiprotein complex that mediates monoubiquitination of lysine residues of histone H2A (lysine-118 in Drosophila or lysine-119 in mammals). The complex is required for stable long-term maintenance of transcriptionally repressed states and is involved in chromatin remodeling.
35103	sterol regulatory element binding protein cleavage	P	The proteolytic release of a transcriptionally active sterol regulatory element binding protein (SREBP) from intracellular membranes, freeing it to move to the nucleus to upregulate transcription of target genes, in response to altered levels of one or more lipids.
35105	sterol regulatory element binding protein import into nucleus	P	The transfer of a sterol regulatory element binding protein (SREBP) into the nucleus, across the nuclear membrane, in response to altered levels of one or more lipids. SREBPs are transcription factors that bind sterol regulatory elements (SREs), DNA motifs found in the promoters of target genes.
35106	operant conditioning	P	Learning to anticipate future events on the basis of past experience with the consequences of one's own behavior.
35107	appendage morphogenesis	P	The process in which the anatomical structures of appendages are generated and organized. An appendage is an organ or part that is attached to the trunk of an organism, such as a limb or a branch.
35108	limb morphogenesis	P	The process in which the anatomical structures of a limb are generated and organized. A limb is a paired appendage of a tetrapod used for locomotion or grasping.
35112	genitalia morphogenesis	P	The process in which the anatomical structures of genitalia are generated and organized. The genitalia are the organs of reproduction or generation, external and internal.
35113	embryonic appendage morphogenesis	P	The process, occurring in the embryo, by which the anatomical structures of the appendage are generated and organized. An appendage is an organ or part that is attached to the trunk of an organism, such as a limb or a branch.
35114	imaginal disc-derived appendage morphogenesis	P	The process in which the anatomical structures of appendages are generated and organized. An appendage is an organ or part that is attached to the trunk of an organism.
35115	embryonic forelimb morphogenesis	P	The process, occurring in the embryo, by which the anatomical structures of the forelimb are generated and organized. The forelimbs are the front limbs of an animal, e.g. the arms of a human.
35116	embryonic hindlimb morphogenesis	P	The process, occurring in the embryo, by which the anatomical structures of the hindlimbs are generated and organized. The hindlimbs are the posterior limbs of an animal.
35118	embryonic pectoral fin morphogenesis	P	The process, occurring in the embryo, by which the anatomical structures of the pectoral fin are generated and organized. Pectoral fins are bilaterally paired fins mounted laterally and located behind the gill covers of fish. These fins are used for lateral mobility and propulsion.
35119	embryonic pelvic fin morphogenesis	P	The process, occurring in the embryo, by which the anatomical structures of the pelvic fin are generated and organized. The pelvic fins are bilaterally paired fins mounted in a ventral-lateral position on most fish. These fins are used primarily for lateral mobility and propulsion.
35120	post-embryonic appendage morphogenesis	P	The process, occurring after embryonic development, by which the anatomical structures of an appendage are generated and organized. An appendage is an organ or part that is attached to the trunk of an organism, such as a limb or a branch.
35122	embryonic medial fin morphogenesis	P	The process, occurring in the embryo, by which the anatomical structures of the medial fin are generated and organized. Medial fins are unpaired fins of fish, usually located dorsomedially or ventromedially and primarily used for stability while swimming.
35123	embryonic dorsal fin morphogenesis	P	The process, occurring in the embryo, by which the anatomical structures of the dorsal fin are generated and organized. A dorsal fin is an unpaired medial fin on the dorsal aspect of a fish that provides lateral stability while swimming. Generally fish have one or two dorsal fins.
35124	embryonic caudal fin morphogenesis	P	The process, occurring in the embryo, by which the anatomical structures of the caudal fin are generated and organized. The caudal fin is an unpaired medial fin mounted at the caudal end of the fish and is the main fin used for propulsion.
35125	embryonic anal fin morphogenesis	P	The process, occurring in the embryo, by which the anatomical structures of the embryonic anal fin are generated and organized. An anal fin is an unpaired medial fin on the ventral aspect near the caudal end of a fish, which provides lateral stability while swimming.
35126	post-embryonic genitalia morphogenesis	P	The process, occurring after embryonic development, by which the anatomical structures of the genitalia are generated and organized.
35127	post-embryonic limb morphogenesis	P	The process, occurring after embryonic development, by which the anatomical structures of the limb are generated and organized. A limb is an appendage of an animal used for locomotion or grasping.
35128	post-embryonic forelimb morphogenesis	P	The process, occurring after embryonic development, by which the anatomical structures of the forelimb are generated and organized. The forelimbs are the front limbs of an organism.
35129	post-embryonic hindlimb morphogenesis	P	The process, occurring after embryonic development, by which the anatomical structures of the hindlimb are generated and organized.
35130	post-embryonic pectoral fin morphogenesis	P	The process, occurring after embryonic development, by which the anatomical structures of the pectoral fin are generated and organized. Pectoral fins are bilaterally paired fins mounted laterally and located behind the gill covers of fish. These fins are used for lateral mobility and propulsion.
35131	post-embryonic pelvic fin morphogenesis	P	The process, occurring after embryonic development, by which the anatomical structures of the pelvic fin are generated and organized. The pelvic fins are bilaterally paired fins mounted in a ventral-lateral position on most fish. These fins are used primarily for lateral mobility and propulsion.
35132	post-embryonic medial fin morphogenesis	P	The process, occurring after embryonic development, by which the anatomical structures of the medial fin are generated and organized. Medial fins are unpaired fins of fish, usually located dorsomedially or ventromedially and primarily used for stability while swimming.
35133	post-embryonic caudal fin morphogenesis	P	The process, occurring after embryonic development, by which the anatomical structures of the caudal fin are generated and organized. The caudal fin is an unpaired medial fin mounted at the caudal end of the fish and is the main fin used for propulsion.
35134	post-embryonic dorsal fin morphogenesis	P	The process, occurring after embryonic development, by which the anatomical structures of the dorsal fin are generated and organized. A dorsal fin is an unpaired medial fin on the dorsal aspect of a fish that provides lateral stability while swimming. Generally fish have one or two dorsal fins.
35135	post-embryonic anal fin morphogenesis	P	The process, occurring after embryonic development, by which the anatomical structures of the anal fin are generated and organized. An anal fin is an unpaired medial fin on the ventral aspect near the caudal end of a fish, which provides lateral stability while swimming.
35136	forelimb morphogenesis	P	The process in which the anatomical structures of the forelimb are generated and organized. The forelimbs are the front limbs of an animal, e.g. the arms of a human.
35137	hindlimb morphogenesis	P	The process in which the anatomical structures of the hindlimb are generated and organized.
35138	pectoral fin morphogenesis	P	The process in which the anatomical structures of the pectoral fin are generated and organized. Pectoral fins are bilaterally paired fins mounted laterally and located behind the gill covers of fish. These fins are used for lateral mobility and propulsion.
35139	pelvic fin morphogenesis	P	The process in which the anatomical structures of the pelvic fin are generated and organized. Pelvic fins are bilaterally paired fins mounted in a ventral-lateral position on most fish. These fins are used primarily for lateral mobility and propulsion.
35141	medial fin morphogenesis	P	The process in which the anatomical structures of the medial fin are generated and organized. A medial fin is an unpaired fin of fish, usually located dorsomedially or ventromedially and primarily used for stability while swimming.
35142	dorsal fin morphogenesis	P	The process in which the anatomical structures of the dorsal fin are generated and organized. A dorsal fin is an unpaired medial fin on the dorsal aspect of fish that provides lateral stability while swimming. Generally fish have one or two dorsal fins.
35143	caudal fin morphogenesis	P	The process in which the anatomical structures of the caudal fin are generated and organized. A caudal fin is an unpaired medial fin mounted at the caudal end of the fish, and is the main fin used for propulsion.
35144	anal fin morphogenesis	P	The process in which the anatomical structures of the anal fin are generated and organized. An anal fin is an unpaired medial fin on the ventral aspect near the caudal end of a fish, which provides lateral stability while swimming.
35145	exon-exon junction complex	C	A multi-subunit complex deposited by the spliceosome upstream of messenger RNA exon-exon junctions. The exon-exon junction complex provides a binding platform for factors involved in mRNA export and nonsense-mediated mRNA decay.
35146	tube fusion	P	The joining of specific branches of a tubular system to form a continuous network.
35147	branch fusion, open tracheal system	P	Fusing of specific tracheal branches in an open tracheal system to branches from neighboring hemisegments to form a continuous tracheal network. Branch fusion is mediated by individual cells at the tip of each branch, which contact a similar cell and undergo a coordinated series of morphogenetic events that create a bicellular fusion joint.
35148	tube formation	P	Creation of the central hole of a tube in an anatomical structure through which gases and/or liquids flow.
35149	lumen formation, open tracheal system	P	Creation of the central hole of a tube in an open tracheal system through which gases flow.
35150	regulation of tube size	P	Ensuring that a tube is of the correct length and diameter. Tube size must be maintained not only during tube formation, but also throughout development and in some physiological processes.
35151	regulation of tube size, open tracheal system	P	Ensuring that an epithelial tube in an open tracheal system is of the correct length and diameter. Tracheal tubes undergo highly regulated tube-size increases during development, expanding up to 40 times their initial size by the end of larval life. Tube size appears to be controlled by regulation of apical membrane expansion and secretion, rather than by changes in cell number, size or shape.
35152	regulation of tube architecture, open tracheal system	P	Ensuring that tracheal cells form and maintain tubular structures with the correct size and shape for their position in the network. This is essential for efficient flow of gases through the tracheal network.
35153	epithelial cell type specification, open tracheal system	P	Allocation of epithelial cells within each migrating branch in an open tracheal system to distinct tracheal cell fates. During the migration phase each branch forms a well-defined number of cell types (including fusion cells, terminal cells and branch cells) at precise positions.
35154	terminal cell fate specification, open tracheal system	P	The process in which a cell in an open tracheal system becomes capable of differentiating autonomously into a terminal cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed. Terminal cells send long and bifurcated hollow branches toward target tissues to allow oxygen exchange.
35155	negative regulation of terminal cell fate specification, open tracheal system	P	Any process that restricts, stops or prevents a cell from adopting a terminal cell fate in an open tracheal system. Once the terminal and fusion fates have been correctly induced, inhibitory feedback loops prevent the remaining branch cells from assuming similar fates.
35156	fusion cell fate specification	P	The process in which a cell becomes capable of differentiating autonomously into a fusion cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed. Fusion cells allow the interconnection of adjacent tracheal metameres during tracheal tube fusion.
35157	negative regulation of fusion cell fate specification	P	Any process that restricts, stops or prevents a cell from adopting a fusion cell fate. Once the terminal and fusion fates have been correctly induced, inhibitory feedback loops prevent the remaining branch cells from assuming similar fates.
35158	regulation of tube diameter, open tracheal system	P	Ensuring that a tube in an open tracheal system is of the correct diameter. When primary branches form their lumens are small (less than 2 micrometers) in caliber and must undergo regulated expansion during larval life to reach their mature size.
35159	regulation of tube length, open tracheal system	P	Ensuring that a tube in an open tracheal system is of the correct length.
35160	maintenance of epithelial integrity, open tracheal system	P	Ensuring that tracheal tubes in an open tracheal system maintain their epithelial structure during the cell shape changes and movements that occur during the branching process.
35161	imaginal disc lineage restriction	P	Formation and/or maintenance of a lineage boundary between compartments in an imaginal disc that cells cannot cross, thus separating the populations of cells in each compartment.
35162	embryonic hemopoiesis	P	The stages of blood cell formation that take place within the embryo.
35163	embryonic hemocyte differentiation	P	The process in which a relatively unspecialized cell derived from the embryonic head mesoderm acquires the specialized features of a mature hemocyte. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen.
35164	embryonic plasmatocyte differentiation	P	The process in which an embryonic mesoderm-derived hemocyte precursor cell acquires the specialized features of the phagocytic blood-cell type, the plasmatocyte.
35165	embryonic crystal cell differentiation	P	The process in which an embryonic mesoderm-derived hemocyte precursor cell acquires the specialized features of a crystal cell. Crystal cells are a class of cells that contain crystalline inclusions and are involved in the melanization of pathogenic material in the hemolymph.
35166	post-embryonic hemopoiesis	P	The stages of blood cell formation that take place after completion of embryonic development.
35167	larval lymph gland hemopoiesis	P	The production of blood cells from the larval lymph gland. The lymph gland consists of three to six bilaterally paired lobes that are attached to the cardioblasts during larval stages, and it degenerates during pupal stages.
35168	larval lymph gland hemocyte differentiation	P	The process in which a relatively unspecialized cell derived from the larval lymph gland acquires the specialized features of a mature hemocyte. The lymph gland consists of three to six bilaterally paired lobes that are attached to the cardioblasts during larval stages, and it degenerates during pupal stages. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen. An example of this process is found in Drosophila melanogaster.
35169	lymph gland plasmatocyte differentiation	P	The process in which a relatively unspecialized larval lymph gland-derived hemocyte precursor cell acquires the specialized features of the phagocytic blood-cell type, the plasmatocyte.
35170	lymph gland crystal cell differentiation	P	The process in which a relatively unspecialized larval lymph gland-derived hemocyte precursor cell acquires the specialized features of a crystal cell. Crystal cells are a class of cells that contain crystalline inclusions and are involved in the melanization of pathogenic material in the hemolymph.
35171	lamellocyte differentiation	P	The process in which a relatively unspecialized hemocyte precursor cell acquires the specialized features of a lamellocyte. Lamellocytes are a hemocyte lineage that exists only in larvae, but are seldom observed in healthy animals. Lamellocytes differentiate massively in the lymph glands after parasitization and are large flat cells devoted to encapsulation of invaders too large to be phagocytosed by plasmatocytes.
35172	hemocyte proliferation	P	The multiplication or reproduction of hemocytes, resulting in the expansion of the cell population. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen.
35173	histone kinase activity	F	Catalysis of the transfer of a phosphate group to a histone. Histones are any of a group of water-soluble proteins found in association with the DNA of plant and animal chromosomes.
35174	histone serine kinase activity	F	Catalysis of the transfer of a phosphate group to a serine residue of a histone. Histones are any of a group of water-soluble proteins found in association with the DNA of plant and animal chromosomes.
35175	histone kinase activity (H3-S10 specific)	F	Catalysis of the transfer of a phosphate group to the serine-10 residue of the N-terminal tail of histone H3.
35176	social behavior	P	Behavior directed towards society, or taking place between members of the same species. Occurs predominantly, or only, in individuals that are part of a group.
35177	larval foraging behavior	P	The movement of a larva through a feeding substrate whilst feeding on food.
35178	turning behavior	P	Fine-tuning the spatial position of an organism in response to variability in their environment. For example, reorientation of an organism in the direction of a food source.
35179	larval turning behavior	P	Fine-tuning the spatial position of a larva in response to variability in their environment. For example, reorientation of a larva in the direction of a food source.
35180	larval wandering behavior	P	The movement of a third instar larva through a substrate in search of a pupation site. This movement occurs without feeding and is characterized by short bursts of forward movement, separated by stops and repeated side-to-side head probes, followed normally by a change in direction.
35181	larval burrowing behavior	P	Digging into the substrate by non-feeding larvae in search for food-free sites suitable for pupation.
35182	female germline ring canal outer rim	C	An electron opaque backbone of the insect ovarian ring canal that is a part of or adjacent to the plasma membrane. The outer rim is established as the cleavage furrow is arrested, and contains F-actin, anillin, glycoproteins and at least one a protein with a high content of phosphorylated tyrosine residues.
35183	female germline ring canal inner rim	C	A proteinaceous actin-rich layer of the insect ovarian ring canal that forms subcortically to the outer rim. The electron dense inner rim accumulates after the final mitotic division of each germline syncytia, and contains actin, a phosphotyrosine protein, and a number of cytoskeletal proteins.
35184	histone threonine kinase activity	F	Catalysis of the transfer of a phosphate group to a threonine residue of a histone. Histones are any of a group of water-soluble proteins found in association with the DNA of plant and animal chromosomes.
35185	preblastoderm mitotic cell cycle	P	The first nine mitotic division cycles of the insect embryo, during which the dividing nuclei lie deep in the interior of the egg and divide nearly synchronously. This is the first phase of the syncytial period where nuclei divide in a common cytoplasm without cytokinesis.
35186	syncytial blastoderm mitotic cell cycle	P	Mitotic division cycles 10 to 13 of the insect embryo. This is the second phase of the syncytial period where nuclei divide in a common cytoplasm without cytokinesis. The majority of migrating nuclei reach the embryo surface during cycle 10, after which they divide less synchronously than before, and the syncytial blastoderm cycles lengthen progressively.
35187	hatching behavior	P	The specific behavior of an organism during the emergence from an egg shell. In Drosophila for example, the larva swings its head reiteratively through a semicircular arc, using its mouth hooks to tear apart the chorion in front of it and thus free itself from within the egg shell.
35188	hatching	P	The emergence of an immature organism from a protective structure.
35189	Rb-E2F complex	C	A multiprotein complex containing a heterodimeric E2F transcription factor and a Retinoblastoma (Rb) family member. This complex is capable of repressing transcription of E2F-regulated genes in order to regulate cell cycle progression.
35190	syncytial nuclear migration	P	The directed movement of nuclei within the syncytial embryo of insects. These precise temporal and spatial patterns of nuclear movement are coordinated with mitotic divisons and are required during blastoderm formation to reposition dividing nuclei from the interior of the syncytial embryo to the cortex.
35191	nuclear axial expansion	P	The stepwise asymmetric spreading out of nuclei internally along the anterior-posterior axis of the developing insect embryo during mitotic cycles 4 to 6. This movement leads to the distribution of nuclei in a hollow ellipsoid underlying the cortex.
35192	nuclear cortical migration	P	The symmetric outward movement of the syncytial nuclei from their positions in the ellipsoid toward the periphery of the embryo, during mitotic cycles 8 and 9. This movement results in the placement of nuclei in a uniform monolayer at the cortex of the developing embryo.
35193	larval central nervous system remodeling	P	Reorganization of the pre-existing, functional larval central nervous system into one that can serve the novel behavioral needs of the adult. An example of this process is found in Drosophila melanogaster.
35194	posttranscriptional gene silencing by RNA	P	Any process of posttranscriptional gene inactivation (silencing) mediated by small RNA molecules that may trigger mRNA degradation or negatively regulate translation.
35195	gene silencing by miRNA	P	Downregulation of gene expression through the action of microRNAs (miRNAs), endogenous 21-24 nucleotide small RNAs processed from stem-loop RNA precursors (pre-miRNAs). Once incorporated into a RNA-induced silencing complex (RISC), miRNAs can downregulate gene expression by either of two posttranscriptional mechanisms: endolytic cleavage of mRNA cleavage or translational repression, usually accompanied by poly-A tail shortening and subsequent degradation of the mRNA.
35196	production of miRNAs involved in gene silencing by miRNA	P	Cleavage of stem-loop RNA precursors into microRNAs (miRNAs), a class of small RNAs that primarily silence genes by blocking the translation of mRNA transcripts into protein.
35197	siRNA binding	F	Interacting selectively and non-covalently with a small interfering RNA, a 21-23 nucleotide RNA that is processed from double stranded RNA (dsRNA) by an RNAse enzyme.
35198	miRNA binding	F	Interacting selectively and non-covalently with a microRNA, a 21-23 nucleotide RNA that is processed from a stem-loop RNA precursor (pre-miRNA) that is encoded within plant and animal genomes.
35199	salt aversion	P	The specific avoidance actions or reactions of an organism in response to the perception of salt.
35200	leg disc anterior/posterior pattern formation	P	The establishment, maintenance and elaboration of the anterior/posterior axis of the leg imaginal disc.
35201	leg disc anterior/posterior lineage restriction	P	Formation and/or maintenance of a lineage boundary between anterior and posterior compartments of the leg disc that cells cannot cross, thus separating the populations of cells in each compartment.
35202	tracheal pit formation in open tracheal system	P	Formation of the tracheal pits, the first tube-like structures to form in the open tracheal system. Once cells are determined to their tracheal cell fate, the tracheal pits arise by invagination of each ectodermal cluster of tracheal placode cells, between 5 and 7 hours after egg laying. An example of this is found in Drosophila melanogaster.
35203	regulation of lamellocyte differentiation	P	Any process that modulates the frequency, rate or extent of lamellocyte differentiation. Lamellocytes differentiate massively in the lymph glands after parasitization and are large flat cells devoted to encapsulation of invaders too large to be phagocytosed by plasmatocytes.
35204	negative regulation of lamellocyte differentiation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of lamellocyte differentiation. Lamellocytes differentiate massively in the lymph glands after parasitization and are large flat cells devoted to encapsulation of invaders too large to be phagocytosed by plasmatocytes.
35205	positive regulation of lamellocyte differentiation	P	Any process that activates or increases the frequency, rate or extent of lamellocyte differentiation. Lamellocytes differentiate massively in the lymph glands after parasitization and are large flat cells devoted to encapsulation of invaders too large to be phagocytosed by plasmatocytes.
35206	regulation of hemocyte proliferation	P	Any process that modulates the frequency, rate or extent of hemocyte proliferation. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen. An example of this is found in Drosophila melanogaster.
35207	negative regulation of hemocyte proliferation	P	Any process that stops, prevents or reduces the rate or extent of hemocyte proliferation. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen. An example of this is found in Drosophila melanogaster.
35208	positive regulation of hemocyte proliferation	P	Any process that activates or increases the rate or extent of hemocyte proliferation. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) that are involved in defense and clotting of hemolymph, but not involved in transport of oxygen. An example of this process is found in Drosophila melanogaster.
35209	pupal development	P	The process whose specific outcome is the progression of the pupa over time, from its formation to the mature structure. The pupa is a dormant life stage interposed between the larval and the adult stages in insects that undergo a complete metamorphosis.
35210	prepupal development	P	The process whose specific outcome is the progression of the prepupa over time, from its formation to the mature structure. The prepupal stage is a life stage interposed between the larval and the pupal stages in insects that undergo a complete metamorphosis. The start of the pre-pupal stage is marked by pupariation, and the end is marked by pupation.
35211	spermathecum morphogenesis	P	The process in which the anatomical structures of a spermathecum, a sperm storage organ, are generated and organized. Paired spermathecae lie at the anterior end of the insect uterus on the dorsal side. Each spermatheca consists of an oval shaped capsule, connected to the uterus by a spermathecal stalk.
35212	cell competition in a multicellular organism	P	Competitive interactions within multicellular organisms between cell populations that differ in growth rates, leading to the elimination of the slowest-growing cells.
35213	clypeo-labral disc development	P	The process whose specific outcome is the progression of the clypeo-labral disc over time, from its formation to the metamorphosis to form adult structures. The clypeo-labral disc develops into the labrum, anterior cibarial plate, fish trap bristles, epistomal sclerite.
35214	eye-antennal disc development	P	Progression of the eye-antennal imaginal disc over time, from its initial formation through to its metamorphosis to form adult structures including the eye, antenna, head capsule and maxillary palps.
35215	genital disc development	P	Progression of the genital imaginal disc over time, from its initial formation through to its metamorphosis to form the adult terminalia, comprising the entire set of internal and external genitalia and analia. Both sexes of Drosophila have a single genital disc formed from the female and male genital primordia, and the anal primordium. The anal primordium develops in both sexes, forming either male or female analia. However, only one of the genital primordia develops in each sex, forming either the male or the female genitalia.
35216	haltere disc development	P	Progression of the haltere imaginal disc over time, from its initial formation through to its metamorphosis to form the adult capitellum, pedicel, haltere sclerite, metathoracic spiracle and metanotum.
35217	labial disc development	P	Progression of the labial imaginal disc over time, from its initial formation through to its metamorphosis to form adult structures including parts of the proboscis.
35218	leg disc development	P	Progression of the leg imaginal disc over time, from its initial formation through to its metamorphosis to form adult structures including the leg, coxa and ventral thoracic pleura.
35219	prothoracic disc development	P	Progression of the prothoracic disc over time, from its initial formation through to its metamorphosis to form the adult humerous and anterior spiracle.
35220	wing disc development	P	Progression of the wing disc over time, from its initial formation through to its metamorphosis to form adult structures including the wing hinge, wing blade and pleura.
35221	genital disc pattern formation	P	The process that gives rise to the patterns of cell differentiation that will arise in the genital imaginal disc.
35222	wing disc pattern formation	P	The process giving rise to the pattern of cell differentiation in the wing imaginal disc.
35223	leg disc pattern formation	P	The process that gives rise to the patterns of cell differentiation in the leg imaginal disc.
35224	genital disc anterior/posterior pattern formation	P	The establishment, maintenance and elaboration of the anterior/posterior axis of the genital disc. An anterior and posterior compartment form in each of the three genital disc primoridia (the female genital disc primordium, the male genital disc primordium and the anal primordium).
35225	determination of genital disc primordium	P	Allocation of embryonic cells to the genital imaginal disc founder populations. Early in development at the blastoderm stage, the anlage of the genital disc of both sexes consists of three primordia: the female genital primoridum lcoated anteriorly, the anal primoridum located posteriorly, and the male gential primordium between the two.
35226	glutamate-cysteine ligase catalytic subunit binding	F	Interacting selectively and non-covalently with the catalytic subunit of glutamate-cysteine ligase.
35227	regulation of glutamate-cysteine ligase activity	P	Any process that modulates the activity of glutamate-cysteine ligase.
35228	negative regulation of glutamate-cysteine ligase activity	P	Any process that stops or reduces the activity of the enzyme glutamate-cysteine ligase.
35229	positive regulation of glutamate-cysteine ligase activity	P	Any process that activates or increases the activity of glutamate-cysteine ligase, typically by lowering its sensitivity to inhibition by glutathione and by increasing its affinity for glutamate.
35230	cytoneme	C	A long, thin, polarized cell projection that contains actin and can extend for distances many times the diameter of the cell. Cytonemes represent extensions of cell cytoplasm and typically have a diameter of approximately 0.2um.
35231	cytoneme assembly	P	Formation of a cytoneme, a long, thin and polarized actin-based cytoplasmic extension that projects from a cell.
35232	germ cell attraction	P	The directed movement of a germ cell from their site of production to the gonad, through the attraction of cells towards their target.
35233	germ cell repulsion	P	The directed movement of a germ cell from their site of production to the gonad, through the repulsion of cells away from a tissue.
35234	ectopic germ cell programmed cell death	P	Programmed cell death of an errant germ line cell that is outside the normal migratory path or ectopic to the gonad. This is an important mechanism of regulating germ cell survival within the embryo.
35235	ionotropic glutamate receptor signaling pathway	P	A series of molecular signals initiated by glutamate binding to a glutamate receptor on the surface of the target cell, followed by the movement of ions through a channel in the receptor complex. Ends with regulation of a downstream cellular process, e.g. transcription.
35236	proctolin receptor activity	F	Combining with the neuropeptide proctolin, to initiate a change in cell activity.
35237	corazonin receptor activity	F	Combining with the neuropeptide corazonin to initiate a change in cell activity.
35238	vitamin A biosynthetic process	P	The chemical reactions and pathways resulting in the formation of any of the vitamin A compounds, retinol, retinal (retinaldehyde) and retinoic acid. Animals cannot synthesize vitamin A de novo, but form it through oxidative cleavage of carotenoids.
35239	tube morphogenesis	P	The process in which the anatomical structures of a tube are generated and organized. Epithelial and endothelial tubes transport gases, liquids and cells from one site to another and form the basic structure of many organs and tissues, with tube shape and organization varying from the single-celled excretory organ in Caenorhabditis elegans to the branching trees of the mammalian kidney and insect tracheal system.
35240	dopamine binding	F	Interacting selectively and non-covalently with dopamine, a catecholamine neurotransmitter formed by aromatic-L-amino-acid decarboxylase from 3,4-dihydroxy-L-phenylalanine.
35241	protein-arginine omega-N monomethyltransferase activity	F	Catalysis of the addition of a methyl group to either of the unmethylated terminal nitrogen atoms (also called omega nitrogen) in peptidyl-arginine to form an omega-N-G-monomethylated arginine residue. The reaction is S-adenosyl-L-methionine + [protein]-L-arginine = S-adenosyl-L-homocysteine + [protein]-Nomega-methyl-L-arginine.
35242	protein-arginine omega-N asymmetric methyltransferase activity	F	Catalysis of the addition of a second methyl group to methylated peptidyl-arginine. Methylation is on the same terminal nitrogen (omega nitrogen) residue that was previously methylated, resulting in asymmetrical peptidyl-N(omega),N(omega)-dimethylated arginine residues.
35243	protein-arginine omega-N symmetric methyltransferase activity	F	Catalysis of the addition of a second methyl group to methylated peptidyl-arginine. Methylation is on the terminal nitrogen (omega nitrogen) residue that is not already methylated, resulting in symmetrical peptidyl-N(omega),N'(omega)-dimethyled arginine residues.
35244	peptidyl-arginine C-methyltransferase activity	F	Catalysis of the transfer of a methyl group to the carbon atom of an arginine residue in a protein.
35245	peptidyl-arginine C-methylation	P	The addition of a methyl group onto a carbon atom of an arginine residue in a protein.
35246	peptidyl-arginine N-methylation	P	The addition of a methyl group onto a nitrogen atom of an arginine residue in a protein.
35247	peptidyl-arginine omega-N-methylation	P	The addition of a methyl group onto a terminal nitrogen (omega nitrogen) atom of an arginine residue in a protein.
35248	alpha-1,4-N-acetylgalactosaminyltransferase activity	F	Catalysis of the transfer of an N-acetylgalactosaminyl residue from UDP-N-acetyl-galactosamine to an acceptor molecule, forming an alpha-1,4 linkage.
35249	synaptic transmission, glutamatergic	P	The process of communication from a neuron to another neuron across a synapse using the neurotransmitter glutamate.
35250	UDP-galactosyltransferase activity	F	Catalysis of the transfer of a galactose group from UDP-galactose to an acceptor molecule.
35251	UDP-glucosyltransferase activity	F	Catalysis of the transfer of a glucosyl group from UDP-glucose to an acceptor molecule.
35252	UDP-xylosyltransferase activity	F	Catalysis of the transfer of a xylosyl group from UDP-xylose to an acceptor molecule.
35253	ciliary rootlet	C	A cytoskeleton-like structure, originating from the basal body at the proximal end of a cilium, and extending proximally toward the cell nucleus. Rootlets are typically 80-100 nm in diameter and contain cross striae distributed at regular intervals of approximately 55-70 nm.
35254	glutamate receptor binding	F	Interacting selectively and non-covalently with a glutamate receptor.
35255	ionotropic glutamate receptor binding	F	Interacting selectively and non-covalently with an ionotropic glutamate receptor. Ionotropic glutamate receptors bind glutamate and exert an effect through the regulation of ion channels.
35256	G-protein coupled glutamate receptor binding	F	Interacting selectively and non-covalently with a G-protein coupled glutamate receptor (a metabotropic glutamate receptor).
35257	nuclear hormone receptor binding	F	Interacting selectively and non-covalently with a nuclear hormone receptor, a ligand-dependent receptor found in the nucleus of the cell.
35258	steroid hormone receptor binding	F	Interacting selectively and non-covalently with a steroid hormone receptor.
35259	glucocorticoid receptor binding	F	Interacting selectively and non-covalently with a glucocorticoid receptor.
35260	internal genitalia morphogenesis	P	The process in which the anatomical structures of the internal genitalia are generated and organized. The internal genitalia are the internal sex organs such as the uterine tube, the uterus and the vagina in female mammals, and the testis, seminal vesicle, ejaculatory duct and prostate in male mammals.
35261	external genitalia morphogenesis	P	The process in which the anatomical structures of the external genitalia are generated and organized. The external genitalia are the outer sex organs, such as the penis or vulva in mammals.
35262	gonad morphogenesis	P	The process in which the anatomical structures of the gonads are generated and organized. A gonad is an animal organ producing gametes, e.g. the testes or the ovary in mammals.
35263	genital disc sexually dimorphic development	P	The sex-specific patterns of primoridia growth and differentiation in the genital imaginal disc. The anal primordium of the genital disc develops in both sexes, but depending on the genetic sex gives rise to either male or female analia. Depending on the genetic sex, only one of the two genital primordia develop. In females the female genital primordium develops and gives rise to the female genitalia whereas the male primordium is repressed. Conversely, in males the male genital primordium develops and gives rise to the male genitalia whereas the female genital primordium is repressed.
35264	multicellular organism growth	P	The increase in size or mass of an entire multicellular organism, as opposed to cell growth.
35265	organ growth	P	The increase in size or mass of an organ. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that function together as to perform a specific function.
35266	meristem growth	P	The increase in size or mass of a meristem, a region of tissue in a plant that is composed of one or more undifferentiated cells capable of undergoing mitosis and differentiation.
35267	NuA4 histone acetyltransferase complex	C	A complex having histone acetylase activity on chromatin, as well as ATPase, DNA helicase and structural DNA binding activities. The complex is thought to be involved in double-strand DNA break repair. Subunits of the human complex include HTATIP/TIP60, TRRAP, RUVBL1, BUVBL2, beta-actin and BAF53/ACTL6A. In yeast, the complex has 13 subunits, including the catalytic subunit Esa1 (homologous to human Tip60).
35268	protein mannosylation	P	The addition of a mannose residue to a protein acceptor molecule.
35269	protein O-linked mannosylation	P	The transfer of mannose from dolichyl activated mannose to the hydroxyl group of a seryl or threonyl residue of a protein acceptor molecule, to form an O-linked protein-sugar linkage.
35270	endocrine system development	P	Progression of the endocrine system over time, from its formation to a mature structure. The endocrine system is a system of hormones and ductless glands, where the glands release hormones directly into the blood, lymph or other intercellular fluid, and the hormones circulate within the body to affect distant organs. The major glands that make up the human endocrine system are the hypothalamus, pituitary, thyroid, parathryoids, adrenals, pineal body, and the reproductive glands which include the ovaries and testes.
35271	ring gland development	P	Progression of the ring gland over time, from its formation to a mature structure. The ring gland is a neuroendocrine organ found in higher Dipterans, which is composed of the prothoracic gland, the corpus allatum, and the corpora cardiacum. The ring gland is the site of production and release of ecdysteroids and juvenile hormones.
35272	exocrine system development	P	Progression of the exocrine system over time, from its formation to a mature structure. The exocrine system is a system of hormones and glands, where the glands secrete straight to a target site via ducts or tubes. The human exocrine system includes the salivary glands, sweat glands and many glands of the digestive system.
35273	phthalate binding	F	Interacting selectively and non-covalently with a phthalate, any ester or salt of phthalic acid.
35274	diphenyl phthalate binding	F	Interacting selectively and non-covalently with diphenyl phthalate, C(20)H(14)O(4).
35275	dibutyl phthalate binding	F	Interacting selectively and non-covalently with dibutyl phthalate, C(16)H(22)O(4).
35276	ethanol binding	F	Interacting selectively and non-covalently with ethanol, CH(3)-CH(2)-OH.
35277	spiracle morphogenesis, open tracheal system	P	The process in which the anatomical structures of a spiracle are generated and organized. Spiracles are the openings in the insect open tracheal system; externally they connect to the epidermis and internally they connect to the tracheal trunk.
35278	miRNA mediated inhibition of translation	P	The process in which microRNAs (miRNAs) block the translation of target mRNAs into proteins. Once incorporated into a RNA-induced silencing complex (RISC), a miRNA will typically mediate repression of translation if the miRNA imperfectly base-pairs with the 3' untranslated regions of target mRNAs
35279	mRNA cleavage involved in gene silencing by miRNA	P	The process in which microRNAs (miRNAs) direct the cleavage of target mRNAs. Once incorporated into a RNA-induced silencing complex (RISC), a miRNA base pairing with near-perfect complementarity to the target mRNA will typically direct targeted endonucleolytic cleavage of the mRNA. Many plant miRNAs downregulate gene expression through this mechanism.
35280	miRNA loading onto RISC involved in gene silencing by miRNA	P	The transfer of a microRNA (miRNA) strand from a miRNA:miRNA duplex onto the RNA-initiated silencing complex (RISC).
35281	pre-miRNA export from nucleus	P	Transport of pre-microRNAs (pre-miRNAs) from the nucleus to the cytoplasm. Pre-miRNAs are a ~60-70 nucleotide stem loop intermediate in miRNA production, produced by the nuclear cleavage of a primary miRNA (pri-mRNA) transcript. Pre-miRNAs are transported from the nucleus to the cytoplasm where further cleavage occurs to produce a mature miRNA product.
35282	segmentation	P	The regionalization process that divides an organism or part of an organism into a series of semi-repetitive parts, or segments, often arranged along a longitudinal axis.
35283	central nervous system segmentation	P	Division of the central nervous system into a series of semi-repetitive parts or segments.
35284	brain segmentation	P	Division of the brain into a series of semi-repetitive parts or segments.
35285	appendage segmentation	P	Division of an appendage, an organ or part that is attached to the main body of an organism, into a series of semi-repetitive parts or segments. Most arthropod appendages, such as the legs and antennae, are visibly segmented.
35287	head segmentation	P	Partitioning the insect head anlage into a fixed number of segmental units. The number of segments composing the insect head has long been a subject of debate, but it is generally agreed that there are 6 or 7 segments. From anterior to posterior the head segments are the procephalic segments (labral, (ocular), antennal and intercalary) and the gnathal segments (mandibular, maxillary and labial).
35288	anterior head segmentation	P	Partitioning the insect head anlage into procephalic (labral, (ocular), antennal and intercalary) segments. The procephalic segments lie anterior to the gnathal (posterior head) segments, and are pattered by different segmentation gene cascades to the abdominal, thoracic and posterior head (gnathal) segments.
35289	posterior head segmentation	P	Partitioning the posterior region of the insect head anlage into gnathal (mandibular, maxillary and labial) segments. Unlike the anterior head (procephalic) segments, formation of the posterior head (gnathal) segments occurs by a similar mechanism to trunk segmentation, where a cascade of gap genes, pair-rule genes and segment-polarity genes subdivide the embryo into progressively smaller domains.
35290	trunk segmentation	P	Partitioning of the blastoderm embryo into trunk segmental units. In Drosophila, the trunk segments include thoracic segments and abdominal segments A1 to A8.
35291	specification of segmental identity, intercalary segment	P	The specification of the characteristic structures of the intercalary segment of the anterior head, following establishment of segment boundaries. Identity is considered to be the aggregate of characteristics by which a structure is recognized.
35292	specification of segmental identity, trunk	P	The specification of the characteristic structures of trunk segments, following establishment of segment boundaries. In Drosophila, the trunk segments include thoracic segments and abdominal segments A1 to A8. Identity is considered to be the aggregate of characteristics by which a structure is recognized.
35293	chitin-based larval cuticle pattern formation	P	The process that gives rise to the patterns of cell differentiation in the chitin-based larval cuticle. An example of this is found in Drosophila melanogaster.
35294	determination of wing disc primordium	P	Allocation of embryonic cells to the wing disc founder populations, groups of cells that are committed to contribute to the formation of a wing imaginal disc.
35295	tube development	P	The process whose specific outcome is the progression of a tube over time, from its initial formation to a mature structure. Epithelial and endothelial tubes transport gases, liquids and cells from one site to another and form the basic structure of many organs and tissues including lung and trachea, kidney, the mammary gland, the vascular system and the gastrointestinal and urinary-genital tracts.
35296	regulation of tube diameter	P	Any process that modulates the diameter of a tube.
35297	regulation of Malpighian tubule diameter	P	Ensuring that the Malpighian tubule is the correct width. Malpighian tubules have a uniform circumference along their length; the circumference of the tubes is eight cells during the time the cells are dividing, after which the cells rearrange producting tubes with a cirumference of two cells.
35298	regulation of Malpighian tubule size	P	Ensuring that a Malpighian tubule is the correct length and diameter.
35299	inositol pentakisphosphate 2-kinase activity	F	Catalysis of the reaction: 1D-myo-inositol 1,3,4,5,6-pentakisphosphate + ATP = 1D-myo-inositol hexakisphosphate + ADP + 2 H(+).
35301	Hedgehog signaling complex	C	A multiprotein complex that binds microtubules in a Hedgehog-dependent manner, and is required for signal transduction by members of the Hedgehog family of proteins. The core components of the complex are the serine/threonine protein kinase Fused, the kinesin motor protein Costal2 (Cos2), and a zinc finger transcription factor (Gli family members in humans, and Cubitus interruptus (Ci) in Drosophila).
35302	ecdysteroid 25-hydroxylase activity	F	Catalysis of the hydroxylation of an ecdysteroid at carbon position 25. Ecdysteroids are a group of polyhydroxylated ketosteroids which initiate post-embryonic development, particularly metamorphosis, in insects and other arthropods.
35303	regulation of dephosphorylation	P	Any process that modulates the frequency, rate or extent of removal of phosphate groups from a molecule.
35304	regulation of protein dephosphorylation	P	Any process that modulates the frequency, rate or extent of removal of phosphate groups from a protein.
35305	negative regulation of dephosphorylation	P	Any process the stops, prevents, or reduces the frequency, rate or extent of removal of phosphate groups from a molecule.
35306	positive regulation of dephosphorylation	P	Any process that activates or increases the frequency, rate or extent of removal of phosphate groups from a molecule.
35307	positive regulation of protein dephosphorylation	P	Any process that activates or increases the frequency, rate or extent of removal of phosphate groups from a protein.
35308	negative regulation of protein dephosphorylation	P	Any process the stops, prevents, or reduces the frequency, rate or extent of removal of phosphate groups from a protein.
35309	wing and notum subfield formation	P	The regionalization process that subdivides the wing imaginal disc into the wing and notum (body wall) subfields, thus determining whether cells ultimately differentiate wing or notum-specific structures.
35310	notum cell fate specification	P	The process in which a cell in the larval wing imaginal disc becomes capable of differentiating autonomously into a notum cell, if left in its normal environment.
35311	wing cell fate specification	P	The process in which a cell in the larval wing imaginal disc becomes capable of differentiating autonomously into a wing cell, if left in its normal environment.
35312	5'-3' exodeoxyribonuclease activity	F	Catalysis of the sequential cleavage of mononucleotides from a free 5' terminus of a DNA molecule.
35313	wound healing, spreading of epidermal cells	P	The migration of an epidermal cell along or through a wound gap that contributes to the reestablishment of a continuous epidermis.
35314	scab formation	P	Formation of hardened covering (a scab) at a wound site. The scab has multiple functions including limiting blood loss, providing structural stability to the wound and guarding against infection.
35315	hair cell differentiation	P	The process in which a relatively unspecialized cell acquires specialized features of a hair cell.
35316	non-sensory hair organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of non-sensory hairs. These hairs are polarized cellular extensions that cover much of the insect epidermis.
35317	imaginal disc-derived wing hair organization	P	A process that is carried out at the cellular level that results in the assembly, arrangement of constituent parts, or disassembly of an imaginal disc-derived wing hair. A wing hair is an actin-rich, polarized, non-sensory apical projection that protrudes from each of the approximately 30,000 wing epithelial cells. An example of this is found in Drosophila melanogaster.
35318	imaginal disc-derived wing hair outgrowth	P	Extrusion of a cellular projection from the apical membrane of an epithelial cell in an imaginal disc-derived wing. Outgrowth initiates approximately 35 hours after puparium formation from the distal side of the cell, and at this stage the cellular extension is termed a prehair.
35319	imaginal disc-derived wing hair elongation	P	Growth of a prehair in the approximately 10 hour period following its emergence from an epidermal cell in an imaginal disc-derived wing. Prehair elongation is guided and/or driven by the polymerization of actin filaments and the orderly crosslinking of filaments into bundles.
35320	imaginal disc-derived wing hair site selection	P	Determination of the site in the cell of an imaginal disc-derived wing at which a prehair initiates outgrowth. Restriction of prehair initiation to the distalmost part of a cell is essential to ensure that each wing epithelial cell produces one adult hair that points distally.
35321	maintenance of imaginal disc-derived wing hair orientation	P	Ensuring that hairs in the imaginal disc-derived wing continue to point distally during development, following the initial establishment of wing hair polarity.
35322	mesenchymal cell migration involved in limb bud formation	P	The orderly movement of a mesenchymal cell from one site to another that will contribute to the formation of a limb bud.
35323	male germline ring canal	C	An intercellular bridge that connects the germline cells of a male cyst.
35324	female germline ring canal	C	An intercellular bridge that connects the germline cells of a female cyst.
35325	Toll-like receptor binding	F	Interacting selectively and non-covalently with a Toll-like protein, a pattern recognition receptor that binds pattern motifs from a variety of microbial sources to initiate an innate immune response.
35326	enhancer binding	F	Interacting selectively and non-covalently with an enhancer, a transcription regulatory region that is somewhat distal from the core promoter and which enhances transcription from that promoter.
35327	transcriptionally active chromatin	C	The ordered and organized complex of DNA and protein that forms regions of the chromosome that are being actively transcribed.
35328	transcriptionally silent chromatin	C	The ordered and organized complex of DNA and protein that forms regions of the chromosome that are not being actively transcribed.
35329	hippo signaling	P	The series of molecular signals mediated by the serine/threonine kinase Hippo or one of its orthologs. In Drosophila, Hippo in complex with the scaffold protein Salvador (Sav), phosphorylates and activates Warts (Wts), which in turn phosphorylates and inactivates the Yorkie (Yki) transcriptional activator. The core fly components hippo, sav, wts and mats are conserved in mammals as STK4/3 (MST1/2), SAV1/WW45, LATS1/2 and MOB1.
35330	regulation of hippo signaling	P	Any process that modulates the frequency, rate or extent of hippo signaling.
35331	negative regulation of hippo signaling	P	Any process that stops, prevents, or reduces the frequency, rate or extent of hippo signaling.
35332	positive regulation of hippo signaling	P	Any process that activates or increases the frequency, rate or extent of hippo signaling.
35333	Notch receptor processing, ligand-dependent	P	The proteolytic cleavages to the Notch protein that occur as a result of ligand binding. Ligand binding at the cell surface exposes an otherwise inaccessible cleavage site in the extracellular portion of Notch, which when cleaved releases a membrane-tethered form of the Notch intracellular domain. Subsequent cleavage within the transmembrane domain then leads to the release of the soluble Notch intracellular domain (NICD).
35334	Notch receptor processing, ligand-independent	P	The proteolytic cleavages to the Notch protein that occur prior to ligand binding. A primary cleavage event within the extracellular domain whilst the Notch protein in still in the secretory pathway, leads to the transportation of a processed heterodimer to the cell surface.
35335	peptidyl-tyrosine dephosphorylation	P	The removal of phosphoric residues from peptidyl-O-phospho-tyrosine to form peptidyl-tyrosine.
35336	long-chain fatty-acyl-CoA metabolic process	P	The chemical reactions and pathways involving long-chain fatty-acyl-CoAs, any derivative of coenzyme A in which the sulfhydryl group is in a thioester linkage with a long-chain fatty-acyl group. Long-chain fatty-acyl-CoAs have chain lengths of C13 or more.
35337	fatty-acyl-CoA metabolic process	P	The chemical reactions and pathways involving a fatty-acyl-CoA, any derivative of coenzyme A in which the sulfhydryl group is in thiolester linkage with a fatty-acyl group.
35338	long-chain fatty-acyl-CoA biosynthetic process	P	The chemical reactions and pathways resulting in the formation of a long-chain fatty-acyl-CoA any derivative of coenzyme A in which the sulfhydryl group is in a thioester linkage with a long-chain fatty-acyl group. Long-chain fatty-acyl-CoAs have chain lengths of C13 or more.
35339	SPOTS complex	C	A multiprotein complex at least composed of serine palmitoyltransferases and ORM proteins (known as ORMDL proteins in mammals and other higher vertebrates) that plays a key role in sphingolipid homeostasis.
35340	inosine transport	P	The directed movement of the purine ribonucleoside inosine, also known as hypoxanthine riboside, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
35341	regulation of inosine transport	P	Any process that modulates the frequency, rate or extent of the directed movement of inosine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
35342	positive regulation of inosine transport	P	Any process that activates or increases the frequency, rate or extent of the directed movement of inosine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
35343	negative regulation of inosine transport	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of inosine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
35344	hypoxanthine transport	P	The directed movement of hypoxanthine, 6-hydroxypurine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
35345	regulation of hypoxanthine transport	P	Any process that modulates the frequency, rate or extent of the directed movement of hypoxanthine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
35346	positive regulation of hypoxanthine transport	P	Any process that activates or increases the frequency, rate or extent of the directed movement of hypoxanthine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
35347	negative regulation of hypoxanthine transport	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of hypoxanthine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
35348	acetyl-CoA transmembrane transport	P	The process in which acetyl-CoA is transported from one side of a membrane to the other by means of some agent such as a transporter or pore. Acetyl-CoA is a derivative of coenzyme A in which the sulfhydryl group is acetylated; it is a metabolite derived from several pathways (e.g. glycolysis, fatty acid oxidation, amino-acid catabolism) and is further metabolized by the tricarboxylic acid cycle. It is a key intermediate in lipid and terpenoid biosynthesis.
35349	coenzyme A transmembrane transport	P	The process in which coenzyme A is transported from one side of a membrane to the other by means of some agent such as a transporter or pore. Coenzyme A, 3'-phosphoadenosine-(5')diphospho(4')pantatheine, is an acyl carrier in many acylation and acyl-transfer reactions in which the intermediate is a thiol ester.
35350	FAD transmembrane transport	P	The process in which flavin-adenine dinucleotide (FAD) is transported from one side of a membrane to the other by means of some agent such as a transporter or pore. FAD forms the coenzyme of the prosthetic group of various flavoprotein oxidoreductase enzymes, in which it functions as an electron acceptor by being reversibly converted to its reduced form.
35351	heme transmembrane transport	P	The process in which heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring, is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.
35352	NAD transmembrane transport	P	The process in which nicotinamide adenine dinucleotide is transported from one side of a membrane to the other by means of some agent such as a transporter or pore; transport may be of either the oxidized form, NAD, or the reduced form, NADH.
35353	nicotinamide mononucleotide transmembrane transport	P	The process in which nicotinamide mononucleotide is transported from one side of a membrane to the other by means of some agent such as a transporter or pore. Nicotinamide mononucleotide is a ribonucleotide in which the nitrogenous base, nicotinamide, is in beta-n-glycosidic linkage with the c-1 position of d-ribose. It is a constituent of NAD and NADP.
35354	Toll-like receptor 1-Toll-like receptor 2 protein complex	C	A heterodimeric protein complex containing Toll-like receptor 1 (TLR1) and Toll-like receptor 2 (TLR2).
35355	Toll-like receptor 2-Toll-like receptor 6 protein complex	C	A heterodimeric protein complex containing Toll-like receptor 2 (TLR2) and Toll-like receptor 6 (TLR6).
35356	cellular triglyceride homeostasis	P	Any process involved in the maintenance of an internal steady state of triglyceride within a cell or between a cell and its external environment.
35357	peroxisome proliferator activated receptor signaling pathway	P	The series of molecular signals initiated by binding of a ligand to any of the peroxisome proliferator activated receptors (alpha, beta or gamma) in the nuclear membrane, and ending with the initiation or termination of the transcription of target genes.
35358	regulation of peroxisome proliferator activated receptor signaling pathway	P	Any process that modulates the frequency, rate or extent of the peroxisome proliferator activated receptor signaling pathway.
35359	negative regulation of peroxisome proliferator activated receptor signaling pathway	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the peroxisome proliferator activated receptor signaling pathway.
35360	positive regulation of peroxisome proliferator activated receptor signaling pathway	P	Any process that activates or increases the frequency, rate or extent of the peroxisome proliferator activated receptor signaling pathway.
35361	Cul8-RING ubiquitin ligase complex	C	A ubiquitin ligase complex in which a cullin from the Cul8 subfamily and a RING domain protein form the catalytic core. In S. cerevisiae, Mms1p acts as the adaptor protein and substrate specificity is conferred by any of a number of different proteins.
35362	protein-DNA ISRE complex assembly	P	The aggregation, arrangement and bonding together of proteins and DNA molecules to form a protein-DNA complex, in which the complex is formed through interaction of the protein(s) with a interferon-stimulated response element (ISRE) in the DNA.
35363	histone locus body	C	A nuclear body associated with the histone gene locus that is thought to contain all of the factors necessary for histone mRNA transcription and pre-mRNA processing. In Drosophila, U7 snRNP is located in the histone locus body rather than the distinct Cajal body.
35364	thymine transport	P	The directed movement of thymine, 5-methyluracil, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
35365	regulation of thymine transport	P	Any process that modulates the frequency, rate or extent of the directed movement of thymine, 5-methyluracil, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
35366	negative regulation of thymine transport	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of thymine, 5-methyluracil, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
35367	positive regulation of thymine transport	P	Any process that activates or increases the frequency, rate or extent of the directed movement of thymine, 5-methyluracil, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
35368	selenocysteine insertion sequence binding	F	Interacting selectively and non-covalently with the selenocysteine insertion sequence (SECIS), a regulatory sequence within mRNA which directs incorporation of a selenocysteine at a stop codon (UGA) during translation.
35369	pre-B cell receptor complex	C	An immunoglobulin-like complex that is present in at least the plasma membrane of pre-B cells, and that is composed of two identical immunoglobulin heavy chains and two surrogate light chains, each composed of the lambda-5 and VpreB proteins, and a signaling subunit, a heterodimer of the Ig-alpha and Ig-beta proteins.
35370	UBC13-UEV1A complex	C	A heterodimeric ubiquitin conjugating enzyme complex that catalyzes assembly of K63-linked polyubiquitin chains and is involved in NF-kappaB activation. In humans at least, the complex comprises the ubiquitin-conjugating enzyme UBC13 and ubiquitin-conjugating enzyme variant 1A (UEV1A).
35371	microtubule plus-end	C	The growing (plus) end of a microtubule. In vitro, microtubules polymerize more quickly at the plus end than at the minus end. In vivo, microtubule growth occurs only at the plus end, and the plus end switches between periods of growth and shortening, a behavior known as dynamic instability.
35372	protein localization to microtubule	P	A process in which a protein is transported to, or maintained at, a microtubule.
35373	chondroitin sulfate proteoglycan binding	F	Interacting selectively and non-covalently with a chondroitin sulfate proteoglycan, any proteoglycan containing chondroitin sulfate as the glycosaminoglycan carbohydrate unit.
35374	chondroitin sulfate binding	F	Interacting selectively and non-covalently with chondroitin sulfate, a glycosaminoglycan made up of two alternating monosaccharides: D-glucuronic acid (GlcA) and N-acetyl-D-galactosamine (GalNAc).
35375	zymogen binding	F	Interacting selectively and non-covalently with a zymogen, an enzymatically inactive precursor of an enzyme that is often convertible to an active enzyme by proteolysis.
35376	sterol import	P	The directed movement of a sterol into a cell or organelle. Sterols are steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule.
35377	transepithelial water transport	P	The directed movement of water (H2O) from one side of an epithelium to the other.
35378	carbon dioxide transmembrane transport	P	A process in which carbon dioxide (CO2) is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.
35379	carbon dioxide transmembrane transporter activity	F	Enables the transfer of carbon dioxide (CO2) from one side of a membrane to the other.
35380	very long-chain-3-hydroxyacyl-CoA dehydrogenase activity	F	Catalysis of the reaction: (S)-3-hydroxyacyl-CoA + NAD(P)+ = 3-oxoacyl-CoA + NAD(P)H + H+, where the acyl group is a very long-chain fatty acid residue. A very long-chain fatty acid is a fatty acid which has a chain length greater than C22.
35381	ATP-gated ion channel activity	F	Enables the transmembrane transfer of an ion by a channel that opens when ATP has been bound by the channel complex or one of its constituent parts.
35382	sterol transmembrane transport	P	The directed movement of a sterol across a membrane into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Sterols are steroids with one or more hydroxyl groups and a hydrocarbon side-chain in the molecule.
35383	thioester metabolic process	P	The chemical reactions and pathways involving a thioester, a compound of general formula RC(=O)SR' in which the linking oxygen in an ester is replaced by a sulfur atom. They are the product of esterification between a carboxylic acid and a thiol.
35384	thioester biosynthetic process	P	The chemical reactions and pathways resulting in the formation of a thioester, a compound of general formula RC(=O)SR' in which the linking oxygen in an ester is replaced by a sulfur atom. They are the product of esterification between a carboxylic acid and a thiol.
35385	Roundabout signaling pathway	P	A series of molecular signals initiated by the binding of a SLIT protein to a Roundabout (ROBO) family receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.
35386	regulation of Roundabout signaling pathway	P	Any process that modulates the frequency, rate or extent of the Roundabout signaling pathway.
35387	negative regulation of Roundabout signaling pathway	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the Roundabout signaling pathway.
35388	positive regulation of Roundabout signaling pathway	P	Any process that activates or increases the frequency, rate or extent of the Roundabout signaling pathway.
35389	establishment of chromatin silencing at silent mating-type cassette	P	The initial formation of a transcriptionally silent chromatin structure such as heterochromatin at silent mating-type loci.
35390	establishment of chromatin silencing at telomere	P	The initial formation of a transcriptionally silent chromatin structure such as heterochromatin at the telomere.
35391	maintenance of chromatin silencing at silent mating-type cassette	P	The maintenance of chromatin in a transcriptionally silent state such as heterochromatin at silent mating-type loci.
35392	maintenance of chromatin silencing at telomere	P	The maintenance of chromatin in a transcriptionally silent state such as heterochromatin at the telomere.
35393	chemokine (C-X-C motif) ligand 9 production	P	The appearance of chemokine (C-X-C motif) ligand 9 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
35394	regulation of chemokine (C-X-C motif) ligand 9 production	P	Any process that modulates the frequency, rate, or extent of production of chemokine (C-X-C motif) ligand 9.
35395	negative regulation of chemokine (C-X-C motif) ligand 9 production	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of production of chemokine (C-X-C motif) ligand 9.
35396	positive regulation of chemokine (C-X-C motif) ligand 9 production	P	Any process that activates or increases the frequency, rate, or extent of production of chemokine (C-X-C motif) ligand 9.
35397	helper T cell enhancement of adaptive immune response	P	Positive regulation of an adaptive immune response mediated via cytokine production by helper T cell.
35398	helper T cell enhancement of T cell mediated immune response	P	Positive regulation of a T cell mediated immune response mediated via cytokine production by a helper T cell.
35399	helper T cell enhancement of B cell mediated immune response	P	Positive regulation of a B cell mediated immune response mediated via cytokine production by a helper T cell.
35400	histone tyrosine kinase activity	F	Catalysis of the transfer of a phosphate group to a tyrosine residue of a histone. Histones are any of a group of water-soluble proteins found in association with the DNA of plant and animal chromosomes.
35401	histone kinase activity (H3-Y41 specific)	F	Catalysis of the transfer of a phosphate group to the tyrosine-41 residue of histone H3.
35402	histone kinase activity (H3-T11 specific)	F	Catalysis of the transfer of a phosphate group to the threonine-11 residue of the N-terminal tail of histone H3.
35403	histone kinase activity (H3-T6 specific)	F	Catalysis of the transfer of a phosphate group to the threonine-6 residue of the N-terminal tail of histone H3.
35404	histone-serine phosphorylation	P	The modification of histones by addition of a phosphate group to a serine residue.
35405	histone-threonine phosphorylation	P	The modification of histones by addition of a phosphate group to a threonine residue.
35406	histone-tyrosine phosphorylation	P	The modification of histones by addition of a phosphate group to a tyrosine residue.
35407	histone H3-T11 phosphorylation	P	The modification of histone H3 by the addition of an phosphate group to a threonine residue at position 11 of the histone.
35408	histone H3-T6 phosphorylation	P	The modification of histone H3 by the addition of an phosphate group to a threonine residue at position 6 of the histone.
35409	histone H3-Y41 phosphorylation	P	The modification of histone H3 by the addition of a phosphate group to a tyrosine residue at position 41 of the histone.
35410	dihydrotestosterone 17-beta-dehydrogenase activity	F	Catalysis of the reaction: 5alpha-dihydrotestosterone + NAD+ = 5alpha-androstane-3,17-dione + NADH.
35411	catenin import into nucleus	P	The directed movement of a catenin protein from the cytoplasm into the nucleus.
35412	regulation of catenin import into nucleus	P	Any process that modulates the rate, frequency or extent of the directed movement of a catenin protein from the cytoplasm into the nucleus.
35413	positive regulation of catenin import into nucleus	P	Any process that increases the rate, frequency or extent of the directed movement of a catenin protein from the cytoplasm into the nucleus.
35414	negative regulation of catenin import into nucleus	P	Any process that decreases the rate, frequency or extent of the directed movement of a catenin protein from the cytoplasm into the nucleus.
35418	protein localization to synapse	P	Any process in which a protein is transported to, and/or maintained at the synapse, the junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell.
35419	activation of MAPK activity involved in innate immune response	P	Any process that initiates the activity of the inactive enzyme MAP kinase in the context of an innate immune response, a defense response mediated by germline encoded components that directly recognize components of potential pathogens.
35420	MAPK cascade involved in innate immune response	P	A MAPK cascade that contributes to an innate immune response, a defense response mediated by germline encoded components that directly recognize components of potential pathogens.
35421	activation of MAPKK activity involved in innate immune response	P	Any process that initiates the activity of the inactive enzyme MAP kinase kinase in the context of an innate immune response, a defense response mediated by germline encoded components that directly recognize components of potential pathogens.
35422	activation of MAPKKK activity involved in innate immune response	P	Any process that initiates the activity of the inactive enzyme MAP kinase kinase kinase in the context of an innate immune response, a defense response mediated by germline encoded components that directly recognize components of potential pathogens.
35423	inactivation of MAPK activity involved in innate immune response	P	Any process that terminates the activity of the active enzyme MAP kinase in the context of an innate immune response, a defense response mediated by germline encoded components that directly recognize components of potential pathogens.
35424	MAPK import into nucleus involved in innate immune response	P	The directed movement of a MAP kinase to the nucleus in the context of an innate immune response, a defense response mediated by germline encoded components that directly recognize components of potential pathogens.
35425	autocrine signaling	P	Signaling between cells of the same type. The signal produced by the signaling cell binds to a receptor on, and affects a cell of the same type.
35426	extracellular matrix-cell signaling	P	Any process that mediates the transfer of information between the extracellular matrix and a cell.
35428	hexose transmembrane transport	P	The directed movement of hexose across a membrane by means of some agent such as a transporter or pore. Hexoses are any aldoses with a chain of six carbon atoms in the molecule.
35429	gluconate transmembrane transport	P	The directed movement of gluconate across a membrane by means of some agent such as a transporter or pore. Gluconate is the aldonic acid derived from glucose.
35430	regulation of gluconate transmembrane transport	P	Any process that modulates the frequency, rate or extent of the directed movement of a gluconate across a membrane by means of some agent such as a transporter or pore.
35431	negative regulation of gluconate transmembrane transport	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of gluconate across a membrane by means of some agent such as a transporter or pore.
35432	positive regulation of gluconate transmembrane transport	P	Any process that activates or increases the frequency, rate or extent of the directed movement of gluconate across a membrane by means of some agent such as a transporter or pore.
35433	acetate transmembrane transport	P	The directed movement of acetate across a membrane by means of some agent such as a transporter or pore. Acetate is the 2-carbon carboxylic acid ethanoic acid.
35434	copper ion transmembrane transport	P	The directed movement of copper cation across a membrane.
35435	phosphate ion transmembrane transport	P	The directed movement of phosphate across a membrane by means of some agent such as a transporter or pore.
35436	triose phosphate transmembrane transport	P	The directed movement of triose phosphate across a membrane by means of some agent such as a transporter or pore. Triose phosphate is any organic three carbon compound phosphate ester.
35437	maintenance of protein localization in endoplasmic reticulum	P	Any process in which a protein is maintained in the endoplasmic reticulum and prevented from moving elsewhere. These include sequestration within the endoplasmic reticulum, protein stabilization to prevent transport elsewhere and the active retrieval of proteins that escape the endoplasmic reticulum.
35438	cyclic-di-GMP binding	F	Interacting selectively and non-covalently with cyclic-di-GMP, cyclic dimeric guanosine monophosphate.
35439	halimadienyl-diphosphate synthase activity	F	Catalysis of the reaction: geranylgeranyl diphosphate = halima-5(6),13-dien-15-yl diphosphate.
35440	tuberculosinol biosynthetic process	P	The chemical reactions and pathways resulting in the formation of tuberculosinol (halima-5,6,dien-15-ol), a secondary metabolite in Mycobacteria.
35441	cell migration involved in vasculogenesis	P	The orderly movement of a cell from one site to another that will contribute to the differentiation of an endothelial cell that will form de novo blood vessels and tubes.
35442	dipeptide transmembrane transport	P	The directed movement of a dipeptide across a membrane by means of some agent such as a transporter or pore. A dipeptide is a combination of two amino acids linked together by a peptide (-CO-NH-) bond.
35443	tripeptide transmembrane transport	P	The directed movement of a tripeptide across a membrane by means of some agent such as a transporter or pore. A tripeptide is a compound containing three amino acids linked together by peptide bonds.
35444	nickel cation transmembrane transport	P	The directed movement of nickel (Ni) cations across a membrane by means of some agent such as a transporter or pore.
35445	borate transmembrane transport	P	The directed movement of borate across a membrane by means of some agent such as a transporter or pore. Borate is the anion (BO3)3-; boron is a group 13 element, with properties which are borderline between metals and non-metals.
35446	cysteine-glucosaminylinositol ligase activity	F	Catalysis of the reaction: 1-(2-amino-2-deoxy-alpha-D-glucopyranoside)-1D-myo-inositol + L-cysteine + ATP = 1-D-myo-inosityl-2-L-cysteinylamido-2-deoxy-alpha-D-glucopyranoside + AMP + diphosphate + 2 H+. 1-(2-amino-2-deoxy-alpha-D-glucopyranoside)-1D-myo-inositol is also known as glucosaminyl-inositol or GlcN-Ins, and 1-D-myo-inosityl-2-L-cysteinylamido-2-deoxy-alpha-D-glucopyranoside as desacetylmycothiol or Cys-GlcN-Ins.
35447	mycothiol synthase activity	F	Catalysis of the reaction: 1-D-myo-inosityl-2-L-cysteinylamido-2-deoxy-alpha-D-glucopyranoside + acetyl-CoA = mycothiol + coenzyme A + H+. Mycothiol is also known as AcCys-GlcN-Ins and 1-D-myo-inosityl-2-L-cysteinylamido-2-deoxy-alpha-D-glucopyranoside as Cys-GlcN-Ins or desacetylmycothiol.
35448	extrinsic component of thylakoid membrane	C	The component of a thylakoid membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
35449	extrinsic component of plastid thylakoid membrane	C	The component of a plastid thylakoid membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
35450	extrinsic component of lumenal side of plastid thylakoid membrane	C	The component of a plastid thylakoid membrane consisting of gene products and protein complexes that are loosely bound to its lumenal surface, but not integrated into the hydrophobic region.
35451	extrinsic component of stromal side of plastid thylakoid membrane	C	The component of a plastid thylakoid membrane consisting of gene products and protein complexes that are loosely bound to its stromal surface, but not integrated into the hydrophobic region.
35452	extrinsic component of plastid membrane	C	The component of a plastid membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
35453	extrinsic component of plastid inner membrane	C	The component of a plastid inner membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
35454	extrinsic component of stromal side of plastid inner membrane	C	The component of a plastid inner membrane consisting of gene products and protein complexes that are loosely bound to its stromal surface, but not integrated into the hydrophobic region.
35455	response to interferon-alpha	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-alpha stimulus. Interferon-alpha is a type I interferon.
35456	response to interferon-beta	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-beta stimulus. Interferon-beta is a type I interferon.
35457	cellular response to interferon-alpha	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-alpha stimulus. Interferon-alpha is a type I interferon.
35458	cellular response to interferon-beta	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-beta stimulus. Interferon-beta is a type I interferon.
35459	cargo loading into vesicle	P	The formation of a macromolecular complex between the coat proteins and proteins and/or lipoproteins that are going to be transported by a vesicle.
35460	L-ascorbate 6-phosphate lactonase activity	F	Catalysis of the reaction: L-ascorbate 6-phosphate + H2O = 3-keto-L-gulonate 6-phosphate.
35461	vitamin transmembrane transport	P	The process in which a vitamin is transported from one side of a membrane to the other by means of some agent such as a transporter or pore. A vitamin is one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body.
35462	determination of left/right asymmetry in diencephalon	P	The establishment of the diencephalon with respect to the left and right halves.
35463	transforming growth factor beta receptor signaling pathway involved in determination of left/right asymmetry	P	A series of molecular signals initiated by the binding of an extracellular ligand to a transforming growth factor beta receptor on the surface of a target cell, which contributes to determination of organismal asymmetry with respect to the left and right halves.
35464	regulation of transforming growth factor receptor beta signaling pathway involved in determination of left/right asymmetry	P	Any process that modulates the frequency, rate or extent of activity of any TGF-beta receptor signaling pathway that is involved in the determination of organismal asymmetry with regard to its left and right halves.
35469	determination of pancreatic left/right asymmetry	P	Determination of the asymmetric location of the pancreas with respect to the left and right halves of the organism.
35470	positive regulation of vascular wound healing	P	Any process that increases the rate, frequency, or extent of blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels and contribute to the series of events that restore integrity to damaged vasculature.
35471	luteinizing hormone signaling pathway involved in ovarian follicle development	P	The series of molecular signals initiated by luteinizing hormone binding to a receptor, where the activated receptor signals via downstream effectors that contribute to progression of the ovarian follicle over time, from its formation to the mature structure.
35472	choriogonadotropin hormone receptor activity	F	Combining with the choriogonadotropin hormone to initiate a change in cell activity.
35473	lipase binding	F	Interacting selectively and non-covalently with any lipase.
35474	selective angioblast sprouting	P	The segregation of angioblasts into discrete arterial and venous vessels from one common precursor vessel.
35475	angioblast cell migration involved in selective angioblast sprouting	P	The directional migration of angioblast cells as part of selective angioblast sprouting, which results in angioblast segregation into arterial and venous populations.
35476	angioblast cell migration	P	The orderly movement of angioblasts, cells involved in blood vessel morphogenesis.
35477	regulation of angioblast cell migration involved in selective angioblast sprouting	P	Any process that modulates the frequency, rate or extent of angioblast cell migration involved in selective angioblast sprouting.
35478	chylomicron binding	F	Interacting selectively and non-covalently with a chylomicron, a large lipoprotein particle (diameter 75-1200 nm) composed of a central core of triglycerides and cholesterol surrounded by a protein-phospholipid coating. The proteins include one molecule of apolipoprotein B-48 and may include a variety of apolipoproteins, including APOAs, APOCs and APOE.
35479	angioblast cell migration from lateral mesoderm to midline	P	The directed movement of angioblasts from the lateral mesoderm to the midline which occurs as part of the formation of the early midline vasculature.
35480	regulation of Notch signaling pathway involved in heart induction	P	Any process that modulates the frequency, rate or extent of the series of molecular signals initiated by binding of an extracellular ligand to a Notch receptor on the surface of the target cell that contributes to heart induction.
35481	positive regulation of Notch signaling pathway involved in heart induction	P	Any process that activates or increases the frequency, rate or extent of the series of molecular signals initiated by binding of an extracellular ligand to a Notch receptor on the surface of the target cell that contributes to heart induction.
35482	gastric motility	P	The spontaneous peristaltic movements of the stomach that aid in digestion, moving food through the stomach and out through the pyloric sphincter into the duodenum.
35483	gastric emptying	P	The process in which the liquid and liquid-suspended solid contents of the stomach exit through the pylorus into the duodenum.
35484	adenine/adenine mispair binding	F	Interacting selectively and non-covalently with double-stranded DNA containing an A/A mispair.
35485	adenine/guanine mispair binding	F	Interacting selectively and non-covalently with double-stranded DNA containing an A/G mispair.
35486	cytosine/cytosine mispair binding	F	Interacting selectively and non-covalently with double-stranded DNA containing a C/C mispair.
35487	thymine/thymine mispair binding	F	Interacting selectively and non-covalently with double-stranded DNA containing a T/T mispair.
35488	cytosine/thymine mispair binding	F	Interacting selectively and non-covalently with double-stranded DNA containing a C/T mispair.
35489	guanine/guanine mispair binding	F	Interacting selectively and non-covalently with double-stranded DNA containing a G/G mispair.
35490	regulation of leukotriene production involved in inflammatory response	P	Any process that modulates the rate, frequency or extent of the synthesis or release of any leukotriene following a stimulus as part of an inflammatory response.
35491	positive regulation of leukotriene production involved in inflammatory response	P	Any process that increases the rate, frequency or extent of the synthesis or release of any leukotriene following a stimulus as part of an inflammatory response.
35492	negative regulation of leukotriene production involved in inflammatory response	P	Any process that decreases the rate, frequency or extent of the synthesis or release of any leukotriene following a stimulus as part of an inflammatory response.
35493	SNARE complex assembly	P	The aggregation, arrangement and bonding together of a set of components to form a SNARE complex, a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers.
35494	SNARE complex disassembly	P	The disaggregation of the SNARE protein complex into its constituent components. The SNARE complex is a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers.
35495	regulation of SNARE complex disassembly	P	Any process that modulates the frequency, rate or extent of disassembly of the SNARE complex. The SNARE complex is a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers.
35496	lipopolysaccharide-1,5-galactosyltransferase activity	F	Catalysis of the reaction: UDP-galactose + lipopolysaccharide = UDP + 1,5 alpha-D-galactosyl-lipopolysaccharide.
35497	cAMP response element binding	F	Interacting selectively and non-covalently with the cyclic AMP response element (CRE), a short palindrome-containing sequence found in the promoters of genes whose expression is regulated in response to cyclic AMP.
35498	carnosine metabolic process	P	The chemical reactions and pathways involving the dipeptide beta-alanyl-L-histidine (carnosine).
35499	carnosine biosynthetic process	P	The chemical reactions and pathways resulting in the formation of the dipeptide beta-alanyl-L-histidine (carnosine).
35500	MH2 domain binding	F	Interacting selectively and non-covalently with the MH2 (MAD homology 2) domain of a protein. The MH2 domain is found at the carboxy terminus of MAD related proteins such as Smads. The MH2 domain mediates interaction with a wide variety of proteins and provides specificity and selectivity to Smad function and also is critical for mediating interactions in Smad oligomers.
35501	MH1 domain binding	F	Interacting selectively and non-covalently with the MH1 (MAD homology 1) domain of a protein. The MH1 domain is found at the amino terminus of MAD related proteins such as Smads and can mediate DNA binding in some proteins. Smads also use the MH1 domain to interact with some transcription factors.
35502	metanephric part of ureteric bud development	P	The development of the portion of the ureteric bud tube that contributes to the morphogenesis of the metanephros.
35503	ureter part of ureteric bud development	P	The development of the portion of the ureteric bud that contributes to the morphogenesis of the ureter. The ureter ureteric bud is the initial structure that forms the ureter.
35504	regulation of myosin light chain kinase activity	P	Any process that modulates the frequency, rate or extent of myosin light chain kinase activity.
35505	positive regulation of myosin light chain kinase activity	P	Any process that activates or increases the frequency, rate or extent of myosin light chain kinase activity.
35506	negative regulation of myosin light chain kinase activity	P	Any process that stops, prevents, or reduces the frequency, rate or extent of myosin light chain kinase activity.
35507	regulation of myosin-light-chain-phosphatase activity	P	Any process that modulates the frequency, rate or extent of myosin-light-chain-phosphatase activity.
35508	positive regulation of myosin-light-chain-phosphatase activity	P	Any process that activates or increases the frequency, rate or extent of myosin-light-chain-phosphatase activity.
35509	negative regulation of myosin-light-chain-phosphatase activity	P	Any process that stops, prevents, or reduces the frequency, rate or extent of myosin-light-chain-phosphatase activity.
35510	DNA dealkylation	P	The removal of an alkyl group from one or more nucleotides within an DNA molecule.
35511	oxidative DNA demethylation	P	Removal of the methyl group from one or more nucleotides within a DNA molecule involving the oxidation (i.e. electron loss) of one or more atoms.
35512	hydrolytic DNA demethylation	P	The hydrolytic removal of the methyl group from one or more nucleotides within a DNA molecule.
35513	oxidative RNA demethylation	P	The removal of the methyl group from one or more nucleotides within an RNA molecule involving oxidation (i.e. electron loss) of one or more atoms.
35514	DNA demethylase activity	F	Catalysis of the removal of a methyl group from one or more nucleosides within a DNA molecule.
35515	oxidative RNA demethylase activity	F	Catalysis of the removal of a methyl group from one or more nucleosides within a RNA molecule involving the oxidation (i.e. electron loss) of one or more atoms.
35516	oxidative DNA demethylase activity	F	Catalysis of the removal of the methyl group from one or more nucleotides within a DNA molecule involving the oxidation (i.e. electron loss) of one or more atoms.
35517	PR-DUB complex	C	A multimeric protein complex that removes monoubiquitin from histone H2A. In Drosophila and mammals, the core of the complex is composed of Calypso/BAP1 and Asx/ASXL1, respectively.
35518	histone H2A monoubiquitination	P	The modification of histone H2A by addition of a single ubiquitin group.
35519	protein K29-linked ubiquitination	P	A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 29 of the ubiquitin monomers, is added to a protein. K29-linked ubiquitination targets the substrate protein for degradation.
35520	monoubiquitinated protein deubiquitination	P	The removal of the ubiquitin group from a monoubiquitinated protein.
35521	monoubiquitinated histone deubiquitination	P	The removal of the ubiquitin group from a monoubiquitinated histone protein.
35522	monoubiquitinated histone H2A deubiquitination	P	The removal of the ubiquitin group from a monoubiquitinated histone H2A protein.
35523	protein K29-linked deubiquitination	P	A protein deubiquitination process in which a K29-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 29 of the ubiquitin monomers, is removed from a protein.
35524	proline transmembrane transport	P	The directed movement of proline, pyrrolidine-2-carboxylic acid, across a membrane by means of some agent such as a transporter or pore.
35525	NF-kappaB p50/p65 complex	C	A heterodimer of NF-kappa B p50 and p65 subunits.
35526	retrograde transport, plasma membrane to Golgi	P	The directed movement of substances from the plasma membrane back to the trans-Golgi network, mediated by vesicles.
35527	3-hydroxypropionate dehydrogenase (NADP+) activity	F	Catalysis of the reaction: 3-hydroxypropanoate + NADP+ = 3-oxopropanoate + H+ + NADPH.
35528	UDP-N-acetylglucosamine biosynthesis involved in chitin biosynthesis	P	The chemical reactions and pathways resulting in the formation of UDP-N-acetylglucosamine, a substance composed of N-acetylglucosamine in glycosidic linkage with uridine diphosphate, that contribute to the biosynthesis of chitin.
35529	NADH pyrophosphatase activity	F	Catalysis of the reaction: NADH + H2O = AMP + NMNH + 2 H+.
35530	chemokine (C-C motif) ligand 6 production	P	The appearance of chemokine (C-C motif) ligand 6 (CCL6) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
35531	regulation of chemokine (C-C motif) ligand 6 production	P	Any process that modulates the frequency, rate, or extent of production of chemokine (C-C motif) ligand 6 (CCL6).
35532	negative regulation of chemokine (C-C motif) ligand 6 production	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of production of chemokine (C-C motif) ligand 6 (CCL6).
35533	positive regulation of chemokine (C-C motif) ligand 6 production	P	Any process that activates or increases the frequency, rate, or extent of production of chemokine (C-C motif) ligand 6 (CCL6).
35534	chemokine (C-C motif) ligand 6 secretion	P	The regulated release of chemokine (C-C motif) ligand 6 (CCL6) from a cell.
35535	regulation of chemokine (C-C motif) ligand 6 secretion	P	Any process that modulates the rate, frequency or extent of the regulated release of chemokine (C-C motif) ligand 6 (CCL6) from a cell.
35536	negative regulation of chemokine (C-C motif) ligand 6 secretion	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of the regulated release of chemokine (C-C motif) ligand 6 (CCL6) from a cell.
35537	positive regulation of chemokine (C-C motif) ligand 6 secretion	P	Any process that activates or increases the frequency, rate, or extent of the regulated release of chemokine (C-C motif) ligand 6 (CCL6) from a cell.
35538	carbohydrate response element binding	F	Interacting selectively and non-covalently with the carbohydrate response element (ChoRE) found in the promoters of genes whose expression is regulated in response to carbohydrates, such as the triglyceride synthesis genes.
35539	8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity	F	Catalysis of the reaction: 8-oxo-7,8-dihydrodeoxyguanosine-triphosphate + H2O = 8-oxo-7,8-dihydrodeoxyguanosine phosphate + diphosphate. 8-oxo-7,8-dihydrodeoxyguanosine-triphosphate, or 8-oxo-dGTP, is the oxidised form of the free guanine nucleotide and can act as a potent mutagenic substrate for DNA synthesis causing transversion mutations. 8-oxo-dGTPase hydrolyses 8-oxo-dGTP to its monophosphate form to prevent the misincorporation of 8-oxo-dGTP into cellular DNA.
35540	positive regulation of SNARE complex disassembly	P	Any process that increases the frequency, rate or extent of disassembly of the SNARE complex. The SNARE complex is a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers.
35541	negative regulation of SNARE complex disassembly	P	Any process that decreases the frequency, rate or extent of disassembly of the SNARE complex. The SNARE complex is a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers.
35542	regulation of SNARE complex assembly	P	Any process that modulates the frequency, rate or extent of assembly of the SNARE complex. The SNARE complex is a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers.
35543	positive regulation of SNARE complex assembly	P	Any process that increases the frequency, rate or extent of assembly of the SNARE complex. The SNARE complex is a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers.
35544	negative regulation of SNARE complex assembly	P	Any process that decreases the frequency, rate or extent of assembly of the SNARE complex. The SNARE complex is a protein complex involved in membrane fusion; a stable ternary complex consisting of a four-helix bundle, usually formed from one R-SNARE and three Q-SNAREs with an ionic layer sandwiched between hydrophobic layers.
35545	determination of left/right asymmetry in nervous system	P	The establishment of the nervous system with respect to the left and right halves.
35546	interferon-beta secretion	P	The regulated release of interferon-beta from a cell.
35547	regulation of interferon-beta secretion	P	Any process that modulates the frequency, rate, or extent of interferon-beta secretion.
35548	negative regulation of interferon-beta secretion	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of interferon-beta secretion.
35549	positive regulation of interferon-beta secretion	P	Any process that activates or increases the frequency, rate, or extent of interferon-beta secretion.
35550	urease complex	C	A multiprotein nickel-containing complex that possesses urease activity (catalysis of the hydrolysis of urea to ammonia and carbon dioxide).
35551	protein initiator methionine removal involved in protein maturation	P	Removal of the initiating methionine or formylmethionine residue from a protein that contributes to protein maturation, the attainment of the full functional capacity of a protein.
35552	oxidative single-stranded DNA demethylation	P	Removal of the methyl group from one or more nucleotides within a single-stranded DNA molecule involving the oxidation (i.e. electron loss) of one or more atoms.
35553	oxidative single-stranded RNA demethylation	P	Removal of the methyl group from one or more nucleotides within a single-stranded RNA molecule involving the oxidation (i.e. electron loss) of one or more atoms.
35554	termination of Roundabout signal transduction	P	The signaling process in which signaling from the receptor ROBO is brought to an end, rather than being reversibly modulated.
35556	intracellular signal transduction	P	The process in which a signal is passed on to downstream components within the cell, which become activated themselves to further propagate the signal and finally trigger a change in the function or state of the cell.
35560	pheophoridase activity	F	Catalysis of the reaction: pheophorbide a + H2O = pyropheophorbide a + methanol + CO2. The reaction occurs in two steps; pheophoridase catalyzes the conversion of pheophorbide a to a precursor of pyropheophorbide a, C-13(2)-carboxylpyropheophorbide a, by demethylation, and then the precursor is decarboxylated non-enzymatically to yield pyropheophorbide a.
35561	regulation of chromatin binding	P	Any process that modulates the frequency, rate or extent of chromatin binding. Chromatin binding is the selective interaction with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase.
35562	negative regulation of chromatin binding	P	Any process that stops or reduces the frequency, rate or extent of chromatin binding. Chromatin binding is the selective interaction with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase.
35563	positive regulation of chromatin binding	P	Any process that increases the frequency, rate or extent of chromatin binding. Chromatin binding is the selective interaction with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase.
35564	regulation of kidney size	P	Any process that modulates the size of a kidney.
35565	regulation of pronephros size	P	Any process that modulates the size of a pronephric kidney.
35566	regulation of metanephros size	P	Any process that modulates the size of a metanephric kidney.
35567	non-canonical Wnt signaling pathway	P	The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via effectors other than beta-catenin.
35568	N-terminal peptidyl-proline methylation	P	The methylation of the N-terminal proline of proteins.
35570	N-terminal peptidyl-serine methylation	P	The methylation of the N-terminal serine of proteins.
35571	N-terminal peptidyl-serine monomethylation	P	The monomethylation of the N-terminal serine of proteins to form the derivative N-methylserine.
35572	N-terminal peptidyl-serine dimethylation	P	The dimethylation of the N-terminal serine of proteins to form the derivative N,N-dimethylserine.
35573	N-terminal peptidyl-serine trimethylation	P	The trimethylation of the N-terminal serine of proteins to form the derivative N,N,N-trimethylserine.
35574	histone H4-K20 demethylation	P	The modification of histone H4 by the removal of a methyl group from lysine at position 20 of the histone.
35575	histone demethylase activity (H4-K20 specific)	F	Catalysis of the reaction: histone H4 N6-methyl-L-lysine (position 20) + 2-oxoglutarate + O2 = histone H4 L-lysine (position 20) + succinate + formaldehyde + CO2. This reaction is the removal of a methyl group from lysine at position 20 of the histone H4 protein.
35576	retinoic acid receptor signaling pathway involved in pronephric field specification	P	The series of molecular signals generated as a consequence of a retinoic acid receptor binding to one of its physiological ligands that results in regions of the embryo being delineated into the area in which the pronephric kidney will develop.
35577	azurophil granule membrane	C	The lipid bilayer surrounding an azurophil granule, a primary lysosomal granule found in neutrophil granulocytes that contains a wide range of hydrolytic enzymes and is released into the extracellular fluid.
35578	azurophil granule lumen	C	The volume enclosed by the membrane of an azurophil granule, a primary lysosomal granule found in neutrophil granulocytes that contains a wide range of hydrolytic enzymes and is released into the extracellular fluid.
35579	specific granule membrane	C	The lipid bilayer surrounding a specific granule, a granule with a membranous, tubular internal structure, found primarily in mature neutrophil cells. Most are released into the extracellular fluid. Specific granules contain lactoferrin, lysozyme, vitamin B12 binding protein and elastase.
35580	specific granule lumen	C	The volume enclosed by the membrane of a specific granule, a granule with a membranous, tubular internal structure, found primarily in mature neutrophil cells. Most are released into the extracellular fluid. Specific granules contain lactoferrin, lysozyme, vitamin B12 binding protein and elastase.
35581	sequestering of extracellular ligand from receptor	P	The process of binding or confining an extracellular signaling ligand, such that the ligand is unable to bind to its cell surface receptor.
35582	sequestering of BMP in extracellular matrix	P	Confining a bone morphogenetic protein (BMP) to the extracellular matrix (ECM), such that it is separated from other components of the signaling pathway, including its cell surface receptor. Bone morphogenetic proteins (BMPs) are secreted as homodimers, non-covalently associated with N-terminal pro-peptides, and are targeted to the extracellular matrix through interaction with matrix proteins.
35583	sequestering of TGFbeta in extracellular matrix	P	Confining TGFbeta to the extracellular matrix (ECM) such that it is separated from other components of the signaling pathway, including its cell surface receptor. TGFbeta is secreted as part of a latent complex that is targeted to the extracellular matrix through latent-TGFbeta-binding protein (LTBP)-mediated association with matrix proteins.
35584	calcium-mediated signaling using intracellular calcium source	P	A series of molecular signals in which a cell uses calcium ions released from an intracellular store to convert a signal into a response.
35585	calcium-mediated signaling using extracellular calcium source	P	A series of molecular signals in which a cell uses calcium ions imported from an extracellular source to convert a signal into a response.
35586	purinergic receptor activity	F	Combining with a purine or purine derivative (purine nucleoside or purine nucleotide) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. A nucleotide is a compound that consists of a nucleoside esterified with a phosphate molecule.
35587	purinergic receptor signaling pathway	P	The series of molecular signals generated as a consequence of a receptor binding to an extracellular purine or purine derivative to initiate a change in cell activity.
35588	G-protein coupled purinergic receptor signaling pathway	P	The series of molecular signals generated as a consequence of a receptor binding to an extracellular purine or purine derivative and transmitting the signal to a heterotrimeric G-protein complex to initiate a change in cell activity.
35589	G-protein coupled purinergic nucleotide receptor signaling pathway	P	The series of molecular signals generated as a consequence of a receptor binding to an extracellular purine nucleotide and transmitting the signal to a heterotrimeric G-protein complex to initiate a change in cell activity.
35590	purinergic nucleotide receptor signaling pathway	P	The series of molecular signals generated as a consequence of a receptor binding to an extracellular purine nucleotide to initiate a change in cell activity.
35591	signaling adaptor activity	F	The binding activity of a molecule that brings together two or more molecules in a signaling pathway, permitting those molecules to function in a coordinated way. Adaptor molecules themselves do not have catalytic activity.
35592	establishment of protein localization to extracellular region	P	The directed movement of a protein to a specific location within the extracellular region.
35593	positive regulation of Wnt signaling pathway by establishment of Wnt protein localization to extracellular region	P	Any process that activates or increases the frequency, rate or extent of the Wnt signaling pathway by the directed movement of a Wnt protein within the extracellular region.
35594	ganglioside binding	F	Interacting selectively and non-covalently with a ganglioside, a ceramide oligosaccharide carrying in addition to other sugar residues, one or more sialic acid residues.
35595	N-acetylglucosaminylinositol deacetylase activity	F	Catalysis of the reaction: 1D-myo-inositol 2-acetamido-2-deoxy-alpha-D-glucopyranoside + H2O = 1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside + acetate. This reaction is the hydrolysis of an acetyl group from N-acetylglucosaminylinositol.
35596	methylthiotransferase activity	F	Catalysis of the addition of a methylthioether group (-SCH3) to a nucleic acid or protein acceptor.
35597	N6-isopentenyladenosine methylthiotransferase activity	F	Catalysis of the methylthiolation (-SCH3 addition) at the C2 of the adenosine ring of N6-isopentenyladenosine (i6A) in tRNA, to form 2-methylthio-N6-isopentenyladenosine (ms2i6A).
35598	N6-threonylcarbomyladenosine methylthiotransferase activity	F	Catalysis of the methylthiolation (-SCH3 addition) at the C2 of the adenosine ring of N6-threonylcarbomyladenosine (t6A) in tRNA, to form 2-methylthio-N6-threonylcarbamoyladenosine (ms2t6A).
35599	aspartic acid methylthiotransferase activity	F	Catalysis of the methylthiolation (-SCH3 addition) of the beta-carbon of peptidyl-aspartic acid to form peptidyl-L-beta-methylthioaspartic acid.
35600	tRNA methylthiolation	P	The addition of a methylthioether group (-SCH3) to a nucleotide in a tRNA molecule.
35601	protein deacylation	P	The removal of an acyl group, any group or radical of the form RCO- where R is an organic group, from a protein amino acid.
35602	fibroblast growth factor receptor signaling pathway involved in negative regulation of apoptotic process in bone marrow	P	The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands, which stops, prevents, or reduces the frequency, rate or extent of the occurrence or rate of cell death by apoptotic process in the bone marrow.
35603	fibroblast growth factor receptor signaling pathway involved in hemopoiesis	P	The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands, which contributes to hemopoiesis.
35604	fibroblast growth factor receptor signaling pathway involved in positive regulation of cell proliferation in bone marrow	P	The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands, which activates or increases the frequency, rate or extent of cell proliferation in the bone marrow.
35605	peptidyl-cysteine S-nitrosylase activity	F	Catalysis of the transfer of a nitric oxide (NO) group to a sulphur atom within a cysteine residue of a protein.
35606	peptidyl-cysteine S-trans-nitrosylation	P	Transfer of a nitric oxide (NO) group from one cysteine residue to another.
35607	fibroblast growth factor receptor signaling pathway involved in orbitofrontal cortex development	P	The series of molecular signals generated as a consequence of a fibroblast growth factor-type receptor binding to one of its physiological ligands, which contributes to the progression of the orbitofrontal cortex over time from its initial formation until its mature state.
35608	protein deglutamylation	P	The removal of a glutamate residue from a protein. Glutamate residues in proteins can be gene-encoded, or added as side chains during the protein modification process of polyglutamylation.
35609	C-terminal protein deglutamylation	P	The removal of a C-terminal, gene-encoded glutamate residue from a protein.
35610	protein side chain deglutamylation	P	The removal of a glutamate residue from the side chain of a protein. Glutamate side chains are added to glutamic acid residues within the primary protein sequence during polyglutamylation.
35611	protein branching point deglutamylation	P	The removal of a branching point glutamate residue. A branching point glutamate connects a glutamate side chain to a gene-encoded glutamate residue.
35612	AP-2 adaptor complex binding	F	Interacting selectively and non-covalently with the AP-2 adaptor complex. The AP-2 adaptor complex is a heterotetrameric AP-type membrane coat adaptor complex that consists of alpha, beta2, mu2 and sigma2 subunits and links clathrin to the membrane surface of a vesicle. In at least humans, the AP-2 complex can be heterogeneric due to the existence of multiple subunit isoforms encoded by different alpha genes (alphaA and alphaC).
35613	RNA stem-loop binding	F	Interacting selectively and non-covalently with a stem-loop in an RNA molecule. An RNA stem-loop is a secondary RNA structure consisting of a double-stranded RNA (dsRNA) stem and a terminal loop.
35614	snRNA stem-loop binding	F	Interacting selectively and non-covalently with a stem-loop in a small nuclear RNA (snRNA). An RNA stem-loop is a secondary RNA structure consisting of a double-stranded RNA (dsRNA) stem and a terminal loop.
35615	clathrin adaptor activity	F	The binding activity of a molecule that brings together clathrin and one or more other molecules, permitting them to function in a coordinated way.
35616	histone H2B conserved C-terminal lysine deubiquitination	P	A histone deubiquitination process in which a ubiquitin monomer is removed from a conserved lysine residue in the C-terminus of histone H2B. The conserved lysine residue is K119 in fission yeast, K123 in budding yeast, or K120 in mammals.
35617	stress granule disassembly	P	The disaggregation of a stress granule into its constituent protein and RNA parts.
35618	root hair	C	A long, thin projection from a root epidermal cell that contains F-actin and tubulin, and a cell wall.
35619	root hair tip	C	The tip portion of an outgrowth of a root epidermal cell.
35620	ceramide transporter activity	F	Enables the directed movement of ceramides into, out of or within a cell, or between cells. Ceramides are a class of lipid composed of sphingosine linked to a fatty acid.
35621	ER to Golgi ceramide transport	P	The directed movement of a ceramide from the endoplasmic reticulum (ER) to the Golgi. Ceramides are a class of lipid composed of sphingosine linked to a fatty acid.
35622	intrahepatic bile duct development	P	The progression of the intrahepatic bile ducts over time, from their formation to the mature structure. Intrahepatic bile ducts (bile ducts within the liver) collect bile from bile canaliculi in the liver, and connect to the extrahepatic bile ducts (bile ducts outside the liver).
35623	renal glucose absorption	P	A renal system process in which glucose is taken up from the collecting ducts and proximal and distal loops of the nephron. In non-mammalian species, absorption may occur in related structures.
35624	receptor transactivation	P	The process in which a receptor is activated by another receptor. Receptor transactivation can occur through different mechanisms and includes cross-talk between signaling pathways where one receptor activates a receptor for a different ligand, and also activation of subunits within a receptor oligomer.
35625	epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway	P	The process in which an epidermal growth factor-activated receptor is activated via signaling events from a G-protein coupled receptor. This is an example of cross-talk between the EGF and GPCR signaling pathways.
35626	juvenile hormone mediated signaling pathway	P	A series of molecular signals initiated by the binding of juvenile hormone to a receptor, and ending with regulation of cell state or activity.
35627	ceramide transport	P	The directed movement of ceramides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Ceramides are a class of lipid composed of sphingosine linked to a fatty acid.
35628	cystic duct development	P	The progression of the cystic duct over time, from its formation to the mature structure. The cystic duct runs from the gall bladder to the common bile duct.
35629	N-terminal protein amino acid N-linked glycosylation	P	Addition of a carbohydrate or carbohydrate derivative unit via a nitrogen (N) atom of the N-terminal amino acid of a protein.
35630	bone mineralization involved in bone maturation	P	The deposition of hydroxyapatite, involved in the progression of the skeleton from its formation to its mature state.
35631	CD40 receptor complex	C	A protein complex that contains at least CD40 (a cell surface receptor of the tumour necrosis factor receptor (TNFR) superfamily), and other signaling molecules.
35632	mitochondrial prohibitin complex	C	A complex composed of two proteins, prohibitin 1 and prohibitin 2 (PHB1/PHB-1 and PHB2/PHB-2) that is highly conserved amongst eukaryotes and associated with the inner mitochondrial membrane. The mitochondrial prohibitin complex is a macromolecular supercomplex composed of repeating heterodimeric subunits of PHB1 and PHB2. The mitochondrial prohibitin complex plays a role in a number of biological processes, including mitochondrial biogenesis and function, development, replicative senescence, and cell death.
35633	maintenance of permeability of blood-brain barrier	P	Preserving the permeability barrier between the blood and the brain in a stable functional or structural state. The cells in the brain are packed tightly together preventing the passage of most molecules from the blood into the brain. Only lipid soluble molecules or those that are actively transported can pass through the blood-brain barrier.
35634	response to stilbenoid	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of exposure to a stilbenoid. Stilbenoids are secondary products of heartwood formation in trees that can act as phytoalexins. Stilbenoids are hydroxylated derivatives of stilbene. They belong to the family of phenylpropanoids and share most of their biosynthesis pathway with chalcones.
35635	entry of bacterium into host cell	P	The process in which a bacterium enters a host cell. The host is defined as the larger of the organisms involved in a symbiotic interaction.
35636	multi-organism signaling	P	The transfer of information between living organisms.
35637	multicellular organismal signaling	P	The transfer of information occurring at the level of a multicellular organism.
35638	signal maturation	P	Any process leading to the attainment of the full functional capacity of a signal. A signal is a physical entity or change in state that is used to transfer information to trigger a response, and is functional when it can activate a receptor.
35639	purine ribonucleoside triphosphate binding	F	Interacting selectively and non-covalently with a purine ribonucleoside triphosphate, a compound consisting of a purine base linked to a ribose sugar esterified with triphosphate on the sugar.
35640	exploration behavior	P	The specific behavior of an organism in response to a novel environment or stimulus.
35641	locomotory exploration behavior	P	The specific movement from place to place of an organism in response to a novel environment.
35642	histone methyltransferase activity (H3-R17 specific)	F	Catalysis of the reaction: S-adenosyl-L-methionine + (histone H3)-arginine (position 17) = S-adenosyl-L-homocysteine + (histone H3)-N-methyl-arginine (position 17). This reaction is the addition of a methyl group to arginine at position 17 of histone H3.
35643	L-DOPA receptor activity	F	Combining with L-DOPA to initiate a change in cell activity. L-DOPA is the modified amino acid (2S)-2-amino-3-(3,4-dihydroxyphenyl) propanoic acid, and is the precursor to dopamine, norepinephrine (noradrenaline) and epinephrine.
35644	phosphoanandamide dephosphorylation	P	The process of removing one or more phosphate groups from a phosphorylated anandamide.
35645	enteric smooth muscle cell differentiation	P	The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell of the intestine.
35646	endosome to melanosome transport	P	The directed movement of substances from endosomes to the melanosome, a specialised lysosome-related organelle.
35647	3-oxo-delta(4,5)-steroid 5-beta-reductase activity	F	Catalysis of the reaction: a 3-oxo-delta-4,5-steroid + NADPH + H(+) = a 5-beta-3-oxo-steroid + NADP(+).
35648	circadian mating behavior	P	The fluctuation in mating behavior that occurs over an approximately 24 hour cycle.
35649	Nrd1 complex	C	A complex that functions in transcription termination of RNA polymerase II transcribed non-coding RNAs. This complex interacts with the carboxy-terminal domain (CTD) of PolII and the terminator sequences in the nascent RNA transcript. In yeast this complex consists of Nrd1p, Nab3p, and Sen1p.
35650	AP-1 adaptor complex binding	F	Interacting selectively and non-covalently with the AP-1 adaptor complex. The AP-1 adaptor complex is a heterotetrameric AP-type membrane coat adaptor complex that consists of beta1, gamma, mu1 and sigma1 subunits and links clathrin to the membrane surface of a vesicle. In at least humans, the AP-1 complex can be heterogeneric due to the existence of multiple subunit isoforms encoded by different genes (gamma1 and gamma2, mu1A and mu1B, and sigma1A, sigma1B and sigma1C).
35651	AP-3 adaptor complex binding	F	Interacting selectively and non-covalently with the AP-3 adaptor complex. The AP-3 adaptor complex is a heterotetrameric AP-type membrane coat adaptor complex that consists of beta3, delta, mu3 and sigma3 subunits and is found associated with endosomal membranes. In at least humans, the AP-3 complex can be heterogeneric due to the existence of multiple subunit isoforms encoded by different genes (beta3A and beta3B, mu3A and mu3B, and sigma3A and sigma3B).
35652	cargo loading into clathrin-coated vesicle	P	Formation of a macromolecular complex between the cytoplasmic coat proteins on clathrin-coated vesicles and proteins and/or lipoproteins that are going to be transported by a vesicle.
35653	cargo loading into clathrin-coated vesicle, AP-1-mediated	P	Formation of a macromolecular complex between proteins of the AP-1 adaptor complex and proteins and/or lipoproteins that are going to be transported by a clathrin-coated vesicle. The AP-1 adaptor protein complex is a component of the cytoplasmic coat found on clathrin-coated vesicles, and binds to sorting signals of cargo to facilitate their trafficking.
35654	cargo loading into clathrin-coated vesicle, AP-3-mediated	P	Formation of a macromolecular complex between proteins of the AP-3 adaptor complex and proteins and/or lipoproteins that are going to be transported by a clathrin-coated vesicle. In some cases, the AP-3 complex is a heterotetrameric AP-type membrane coat adaptor complex that, in some organisms, links clathrin to the membrane surface of a vesicle.
35655	interleukin-18-mediated signaling pathway	P	A series of molecular signals initiated by the binding of interleukin-18 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.
35656	kinesin-associated melanosomal adaptor activity	F	The activity of linking kinesins, cytoplasmic proteins responsible for moving vesicles and organelles towards the distal end of microtubules, to melanosomes.
35657	eRF1 methyltransferase complex	C	A protein complex required for the methylation of a glutamine (Gln) residue in the protein release factor eRF1. In S. cerevisiae, this complex consists of at least Trm112p and Mtq2p.
35658	Mon1-Ccz1 complex	C	A protein complex that functions as a guanine nucleotide exchange factor (GEF) and converts Rab-GDP to Rab-GTP. In S. cerevisiae, this complex consists of at least Mon1 and Ccz1, and serves as a GEF for the Rab Ypt7p.
35659	Wnt signaling pathway involved in wound healing, spreading of epidermal cells	P	The series of molecular signals initiated by binding of Wnt protein to a frizzled family receptor on the surface of a cell in the epidermis that contributes to the migration of an epidermal cell along or through a wound gap to reestablish a continuous epidermis.
35660	MyD88-dependent toll-like receptor 4 signaling pathway	P	Any series of molecular signals generated as a consequence of binding to a toll-like 4 receptor, where the MyD88 adaptor molecule mediates transduction of the signal. Toll-like 4 receptors bind bacterial lipopolysaccharide (LPS) to initiate an innate immune response.
35661	MyD88-dependent toll-like receptor 2 signaling pathway	P	Any series of molecular signals generated as a consequence of binding to a toll-like 2 receptor where the MyD88 adaptor molecule mediates transduction of the signal. Toll-like 2 receptors are pattern recognition receptors that bind microbial pattern motifs to initiate an innate immune response.
35662	Toll-like receptor 4 binding	F	Interacting selectively and non-covalently with a Toll-like 4 protein, a pattern recognition receptor that binds bacterial lipopolysaccharide (LPS) to initiate an innate immune response.
35663	Toll-like receptor 2 binding	F	Interacting selectively and non-covalently with a Toll-like 2 protein, a pattern recognition receptor that binds microbial pattern motifs to initiate an innate immune response.
35664	TIRAP-dependent toll-like receptor signaling pathway	P	Any series of molecular signals generated as a consequence of binding to a toll-like receptor where the TIRAP/MAL adaptor mediates transduction of the signal. Toll-like receptors directly bind pattern motifs from a variety of microbial sources to initiate innate immune response.
35665	TIRAP-dependent toll-like receptor 4 signaling pathway	P	Any series of molecular signals generated as a consequence of binding to a toll-like receptor 4 where the TIRAP/MAL adaptor mediates transduction of the signal. Toll-like 4 receptors are pattern recognition receptors that bind bacterial lipopolysaccharide (LPS) to initiate an innate immune response.
35666	TRIF-dependent toll-like receptor signaling pathway	P	Any series of molecular signals generated as a consequence of binding to a toll-like receptor where the TRIF adaptor mediates transduction of the signal. Toll-like receptors directly bind pattern motifs from a variety of microbial sources to initiate innate immune response.
35667	TRIF-dependent toll-like receptor 4 signaling pathway	P	Any series of molecular signals generated as a consequence of binding to a toll-like 4 receptor where the TRIF adaptor mediates transduction of the signal. Toll-like 4 receptors are pattern recognition receptors that bind bacterial lipopolysaccharide (LPS) to initiate an innate immune response.
35668	TRAM-dependent toll-like receptor signaling pathway	P	Any series of molecular signals generated as a consequence of binding to a toll-like receptor where the TRAM adaptor mediates transduction of the signal. Toll-like receptors directly bind pattern motifs from a variety of microbial sources to initiate innate immune response.
35669	TRAM-dependent toll-like receptor 4 signaling pathway	P	Any series of molecular signals generated as a consequence of binding to a toll-like receptor 4 where the TRAM adaptor mediates transduction of the signal. Toll-like 4 receptors are pattern recognition receptors that bind bacterial lipopolysaccharide (LPS) to initiate an innate immune response.
35670	plant-type ovary development	P	The process whose specific outcome is the progression of an ovary that produces an ovule over time, from its formation to the mature structure. The ovary is the enlarged basal portion of a carpel and matures into a fruit. An ovule is the multicellular structure that gives rise to and contains the female reproductive cells, and develops into a seed.
35671	enone reductase activity	F	Catalysis of the reaction: an enone + NADPH + H+ = a ketone + NADP+.
35672	oligopeptide transmembrane transport	P	The directed movement of an oligopeptide across a membrane by means of some agent such as a transporter or pore. Oligopeptides are molecules that contain a small number (2 to 20) of amino-acid residues connected by peptide linkages.
35673	oligopeptide transmembrane transporter activity	F	Enables the transfer of oligopeptides from one side of the membrane to the other.
35674	tricarboxylic acid transmembrane transport	P	The process in which tricarboxylic acids are transported from one side of a membrane to the other by means of some agent such as a transporter or pore.
35675	neuromast hair cell development	P	The process whose specific outcome is the progression of a neuromast hair cell over time, from its formation to the mature structure. A neuromast hair cell is a hair cell that acts as a sensory receptor of the neuromast; it is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. Cell development does not include the steps involved in committing a cell to a specific fate.
35676	anterior lateral line neuromast hair cell development	P	The process whose specific outcome is the progression of an anterior lateral line neuromast hair cell over time, from its formation to the mature structure. A neuromast hair cell is a hair cell that acts as a sensory receptor of the neuromast; it is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. Cell development does not include the steps involved in committing a cell to a specific fate.
35677	posterior lateral line neuromast hair cell development	P	The process whose specific outcome is the progression of a posterior lateral line neuromast hair cell over time, from its formation to the mature structure. A neuromast hair cell is a hair cell that acts as a sensory receptor of the neuromast; it is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. Cell development does not include the steps involved in committing a cell to a specific fate.
35678	neuromast hair cell morphogenesis	P	The change in form (cell shape and size) that occurs when a neuromast hair cell progresses from its initial formation to its mature state. A neuromast hair cell is a hair cell that acts as a sensory receptor of the neuromast; it is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface.
35679	anterior lateral line neuromast hair cell morphogenesis	P	The change in form (cell shape and size) that occurs when an anterior lateral line neuromast hair cell progresses from its initial formation to its mature state. A neuromast hair cell is a hair cell that acts as a sensory receptor of the neuromast; it is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface.
35680	posterior lateral line neuromast hair cell morphogenesis	P	The change in form (cell shape and size) that occurs when a posterior lateral line neuromast hair cell progresses from its initial formation to its mature state. A neuromast hair cell is a hair cell that acts as a sensory receptor of the neuromast; it is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface.
35681	toll-like receptor 15 signaling pathway	P	Any series of molecular signals generated as a consequence of binding to toll-like receptor 15.
35682	toll-like receptor 21 signaling pathway	P	Any series of molecular signals generated as a consequence of binding to toll-like receptor 21.
35683	memory T cell extravasation	P	The migration of a memory T cell from the blood vessels into the surrounding tissue. A memory T cell is a distinctly differentiated long-lived T cell that has the phenotype CD45RO-positive and CD127-positive.
35684	helper T cell extravasation	P	The migration of a helper T cell from the blood vessels into the surrounding tissue. A helper T-cell is an effector T cell that provides help in the form of secreted cytokines to other immune cells.
35685	helper T cell diapedesis	P	The passage of a helper T cell between the tight junctions of endothelial cells lining blood vessels, typically the fourth and final step of cellular extravasation.
35686	sperm fibrous sheath	C	A cytoskeletal structure surrounding the axoneme and outer dense fibers of the sperm flagellum. Consists of two longitudinal columns connected by closely arrayed semicircular ribs that assemble from distal to proximal throughout spermiogenesis. The fibrous sheath probably influences the degree of flexibility, plane of flagellar motion, and the shape of the flagellar beat.
35687	T-helper 1 cell extravasation	P	The migration of a T-helper 1 cell from the blood vessels into the surrounding tissue. A T-helper 1 cell is a CD4-positive, alpha-beta T cell that has the phenotype T-bet-positive and produces interferon-gamma.
35688	T-helper 1 cell diapedesis	P	The passage of a T-helper 1 cell between the tight junctions of endothelial cells lining blood vessels, typically the fourth and final step of cellular extravasation. A T-helper 1 cell is a CD4-positive, alpha-beta T cell that has the phenotype T-bet-positive and produces interferon-gamma.
35689	chemokine (C-C motif) ligand 5 signaling pathway	P	A series of molecular signals initiated by the binding of the chemokine CCL5 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.
35690	cellular response to drug	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a drug stimulus. A drug is a substance used in the diagnosis, treatment or prevention of a disease.
35691	macrophage migration inhibitory factor signaling pathway	P	A series of molecular signals initiated by the binding of macrophage migration inhibitory factor to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.
35692	macrophage migration inhibitory factor receptor complex	C	A protein complex that binds macrophage migration inhibitory factor. Comprises CD74 and CD44 cell surface proteins.
35693	NOS2-CD74 complex	C	A protein complex comprising nitric oxide synthase 2 and CD74. This stable complex formation is thought to prevent CD74 degradation by caspases.
35694	mitochondrial protein catabolic process	P	The chemical reactions and pathways resulting in the breakdown of a mitochondrial protein. This process is necessary to maintain the healthy state of mitochondria and is thought to occur via the induction of an intramitochondrial lysosome-like organelle that acts to eliminate the damaged oxidised mitochondrial proteins without destroying the mitochondrial structure.
35695	mitophagy by induced vacuole formation	P	The process in which cells degrade mitochondria by inducing a vacuole-like structure which directly engulfs and degrades the unhealthy mitochondria by accumulating lysosomes.
35696	monocyte extravasation	P	The migration of a monocyte from the blood vessels into the surrounding tissue.
35697	CD8-positive, alpha-beta T cell extravasation	P	The migration of a CD8-positive, alpha-beta T cell from the blood vessels into the surrounding tissue.
35698	CD8-positive, alpha-beta cytotoxic T cell extravasation	P	The migration of a CD8-positive, alpha-beta cytotoxic T cell from the blood vessels into the surrounding tissue.
35699	T-helper 17 cell extravasation	P	The migration of a T-helper 17 cell from the blood vessels into the surrounding tissue.
35700	astrocyte chemotaxis	P	The directed movement of an astrocyte guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis).
35701	hematopoietic stem cell migration	P	The orderly movement of a hematopoietic stem cell from one site to another. A hematopoietic stem cell is a cell from which all cells of the lymphoid and myeloid lineages develop, including blood cells and cells of the immune system.
35702	monocyte homeostasis	P	The process of regulating the proliferation and elimination of monocytes such that the total number of monocytes within a whole or part of an organism is stable over time in the absence of an outside stimulus.
35703	monocyte migration into blood stream	P	The movement of a monocyte from the bone marrow to the blood stream.
35704	helper T cell chemotaxis	P	The directed movement of a helper T cell in response to an external stimulus.
35705	T-helper 17 cell chemotaxis	P	The directed movement of a T-helper 17 cell in response to an external stimulus.
35706	T-helper 1 cell chemotaxis	P	The directed movement of a T-helper 1 cell in response to an external stimulus.
35707	T-helper 2 cell chemotaxis	P	The directed movement of a T-helper 2 cell in response to an external stimulus.
35708	interleukin-4-dependent isotype switching to IgE isotypes	P	The switching of activated B cells from IgM biosynthesis to IgE biosynthesis, accomplished through a recombination process involving an intrachromosomal deletion between switch regions that reside 5' of the IgM and IgE constant region gene segments in the immunoglobulin heavy chain locus, that is dependent on the activity of interleukin 4 (IL-4).
35709	memory T cell activation	P	The change in morphology and behavior of a memory T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.
35710	CD4-positive, alpha-beta T cell activation	P	The change in morphology and behavior of a CD4-positive, alpha-beta T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.
35711	T-helper 1 cell activation	P	The change in morphology and behavior of a T-helper 1 cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.
35712	T-helper 2 cell activation	P	The change in morphology and behavior of a T helper 2 cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.
35713	response to nitrogen dioxide	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrogen dioxide (NO2) stimulus.
35714	cellular response to nitrogen dioxide	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrogen dioxide (NO2) stimulus.
35715	chemokine (C-C motif) ligand 2 binding	F	Interacting selectively and non-covalently with chemokine (C-C motif) ligand 2.
35716	chemokine (C-C motif) ligand 12 binding	F	Interacting selectively and non-covalently with chemokine (C-C motif) ligand 12.
35717	chemokine (C-C motif) ligand 7 binding	F	Interacting selectively and non-covalently with chemokine (C-C motif) ligand 7.
35718	macrophage migration inhibitory factor binding	F	Interacting selectively and non-covalently with the cytokine, macrophage migration inhibitory factor.
35719	tRNA import into nucleus	P	The directed movement of tRNA from the cytoplasm to the nucleus.
35720	intraciliary anterograde transport	P	The directed movement of large protein complexes along microtubules from the cell body toward the tip of a cilium (also called flagellum), mediated by motor proteins.
35721	intraciliary retrograde transport	P	The directed movement of large protein complexes along microtubules from the tip of a cilium (also called flagellum) toward the cell body, mediated by motor proteins.
35722	interleukin-12-mediated signaling pathway	P	A series of molecular signals initiated by the binding of interleukin-12 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.
35723	interleukin-15-mediated signaling pathway	P	A series of molecular signals initiated by the binding of interleukin-15 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.
35724	CD24 biosynthetic process	P	The chemical reactions and pathways resulting in the formation of CD24, a CD marker and cell adhesion molecule that occurs on many B-lineage cells and mature granulocytes, and is involved in B cell activation and differentiation as well as T cell co-stimulation.
35725	sodium ion transmembrane transport	P	A process in which a sodium ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.
35726	common myeloid progenitor cell proliferation	P	The multiplication or reproduction of common myeloid progenitor cells, resulting in the expansion of a cell population. A common myeloid progenitor cell is a progenitor cell committed to the myeloid lineage.
35727	lysophosphatidic acid binding	F	Interacting selectively and non-covalently with lysophosphatidic acid (LPA), a phospholipid derivative that acts as a potent mitogen due to its activation of high-affinity G-protein-coupled receptors.
35728	response to hepatocyte growth factor	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hepatocyte growth factor stimulus.
35729	cellular response to hepatocyte growth factor stimulus	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hepatocyte growth factor stimulus.
35730	S-nitrosoglutathione binding	F	Interacting selectively and non-covalently with S-nitrosoglutathione, a nitrosothiol considered to be a natural nitric oxide (NO) donor involved in S-nitrosylation, and in the storage and transport of nitric oxide in biological systems.
35731	dinitrosyl-iron complex binding	F	Interacting selectively and non-covalently with a dinitrosyl-iron complex. Nitric oxide (NO) is stored as dinitrosyl-iron complexes, which form spontaneously from Glutathione (GSH), S-nitrosoglutathione, and trace amounts of ferrous ions, or by reaction of iron-sulfur centers with NO.
35732	nitric oxide storage	P	The accumulation and maintenance in cells or tissues of nitric oxide (NO). Nitric oxide is stored in the form of dinitrosyl-iron complexes, which are stabilized, and possibly sequestered, by binding to glutathione S-transferase proteins.
35733	hepatic stellate cell activation	P	A change in the morphology or behavior of a hepatic stellate cell resulting from exposure to a cytokine, chemokine, hormone, cellular ligand or soluble factor.
35735	intraciliary transport involved in cilium assembly	P	The bidirectional movement of large protein complexes along microtubules within a cilium that contributes to cilium assembly.
35736	cell proliferation involved in compound eye morphogenesis	P	The multiplication or reproduction of cells, resulting in the expansion of a cell population that contributes to compound eye morphogenesis.
35737	injection of substance in to other organism	P	The process of forcing a substance into another organism, either by penetrating the skin of the other organism or by applying the substance externally to a sensitive tissue such as those that surround the eyes.
35738	envenomation resulting in modification of morphology or physiology of other organism	P	The process which begins with venom being forced into an organism by the bite or sting of another organism, and ends with the manifestation of some change or damage to the bitten organism.
35739	CD4-positive, alpha-beta T cell proliferation	P	The expansion of a CD4-positive, alpha-beta T cell population by cell division.
35740	CD8-positive, alpha-beta T cell proliferation	P	The expansion of a CD8-positive, alpha-beta T cell population by cell division.
35741	activated CD4-positive, alpha-beta T cell proliferation	P	The expansion of an activated CD4-positive, alpha-beta T cell population by cell division.
35742	activated CD8-positive, alpha-beta T cell proliferation	P	The expansion of an activated CD8-positive, alpha-beta T cell population by cell division.
35743	CD4-positive, alpha-beta T cell cytokine production	P	Any process that contributes to cytokine production by a CD4-positive, alpha-beta T cell.
35744	T-helper 1 cell cytokine production	P	Any process that contributes to cytokine production by a T-helper 1 cell.
35745	T-helper 2 cell cytokine production	P	Any process that contributes to cytokine production by a T-helper 2 cell.
35746	granzyme A production	P	The appearance of granzyme A due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
35747	natural killer cell chemotaxis	P	The directed movement of a natural killer cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis).
35748	myelin sheath abaxonal region	C	The region of the myelin sheath furthest from the axon.
35749	myelin sheath adaxonal region	C	The region of the myelin sheath nearest to the axon.
35750	protein localization to myelin sheath abaxonal region	P	Any process in which a protein is transported to, and/or maintained in, the abaxonal region of the myelin sheath. The abaxonal region is the region of the myelin sheath furthest from the axon.
35751	regulation of lysosomal lumen pH	P	Any process that modulates the pH of the lysosomal lumen, measured by the concentration of the hydrogen ion.
35752	lysosomal lumen pH elevation	P	Any process that increases the pH of the lysosomal lumen, measured by the concentration of the hydrogen ion.
35753	maintenance of DNA trinucleotide repeats	P	Any process involved in sustaining the fidelity and copy number of DNA trinucleotide repeats. DNA trinucleotide repeats are naturally occurring runs of three base-pairs.
35754	B cell chemotaxis	P	The directed movement of a B cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis).
35755	cardiolipin hydrolase activity	F	Catalysis of the hydrolysis of cardiolipin (1,3-bis(3-phosphatidyl)glycerol) to form phosphatidic acid (PA).
35756	transepithelial migration of symbiont in host	P	The directional movement of an organism from one side of an epithelium to the other within its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
35757	chemokine (C-C motif) ligand 19 binding	F	Interacting selectively and non-covalently with chemokine (C-C motif) ligand 19.
35758	chemokine (C-C motif) ligand 21 binding	F	Interacting selectively and non-covalently with chemokine (C-C motif) ligand 21.
35759	mesangial cell-matrix adhesion	P	The binding of a mesangial cell to the extracellular matrix via adhesion molecules. A mesangial cell is a cell that encapsulates the capillaries and venules in the kidney.
35760	cytoplasmic polyadenylation-dependent rRNA catabolic process	P	The chemical reactions and pathways occurring in the cytoplasm and resulting in the breakdown of a ribosomal RNA (rRNA) molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target rRNA truncated degradation intermediate.
35761	dorsal motor nucleus of vagus nerve maturation	P	A developmental process, independent of morphogenetic (shape) change, that is required for the dorsal motor nucleus of the vagus nerve to attain its fully functional state.
35762	dorsal motor nucleus of vagus nerve morphogenesis	P	The process in which the dorsal motor nucleus of the vagus nerve is generated and organized. Morphogenesis pertains to the creation of form.
35763	dorsal motor nucleus of vagus nerve structural organization	P	The process that contributes to the act of creating the structural organization of the dorsal motor nucleus of the vagus nerve. This process pertains to the physical shaping of a rudimentary structure.
35764	dorsal motor nucleus of vagus nerve formation	P	The process that gives rise to the dorsal motor nucleus of the vagus nerve. This process pertains to the initial formation of a structure from unspecified parts.
35765	motor neuron precursor migration involved in dorsal motor nucleus of vagus nerve formation	P	The orderly movement of a motor neuron precursor cell that contributes to formation of the dorsal motor nucleus of the vagus nerve.
35766	cell chemotaxis to fibroblast growth factor	P	The directed movement of a motile cell in response to the presence of fibroblast growth factor (FGF).
35767	endothelial cell chemotaxis	P	The directed movement of an endothelial cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis).
35768	endothelial cell chemotaxis to fibroblast growth factor	P	The directed movement of an endothelial cell in response to the presence of fibroblast growth factor (FGF).
35769	B cell chemotaxis across high endothelial venule	P	The movement of a B cell to cross a high endothelial venule in response to an external stimulus.
35770	ribonucleoprotein granule	C	A non-membranous macromolecular complex containing proteins and translationally silenced mRNAs. RNA granules contain proteins that control the localization, stability, and translation of their RNA cargo. Different types of RNA granules (RGs) exist, depending on the cell type and cellular conditions.
35771	interleukin-4-mediated signaling pathway	P	A series of molecular signals initiated by the binding of interleukin-4 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.
35772	interleukin-13-mediated signaling pathway	P	A series of molecular signals initiated by the binding of interleukin-13 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.
35773	insulin secretion involved in cellular response to glucose stimulus	P	The regulated release of proinsulin from secretory granules (B granules) in the B cells of the pancreas; accompanied by cleavage of proinsulin to form mature insulin, in response to a glucose stimulus.
35774	positive regulation of insulin secretion involved in cellular response to glucose stimulus	P	Any process that increases the frequency, rate or extent of the regulated release of insulin that contributes to the response of a cell to glucose.
35775	pronephric glomerulus morphogenesis	P	The process in which the anatomical structures of the pronephric glomerulus are generated and organized. The pronephric glomerulus is part of the pronephric nephron and is restricted to one body segment.
35776	pronephric proximal tubule development	P	The progression of the pronephric proximal tubule over time, from its formation to the mature structure. A pronephric nephron tubule is an epithelial tube that is part of the pronephros.
35777	pronephric distal tubule development	P	The process whose specific outcome is the progression of the pronephric distal tubule over time, from its formation to the mature structure. A pronephric nephron tubule is an epithelial tube that is part of the pronephros.
35778	pronephric nephron tubule epithelial cell differentiation	P	The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the pronephric nephron tubule as it progresses from its formation to the mature state.
35779	angioblast cell differentiation	P	The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of an angioblast cell. Angioblasts are one of the two products formed from hemangioblast cells (the other being pluripotent hemopoietic stem cells).
35780	CD80 biosynthetic process	P	The chemical reactions and pathways resulting in the formation of CD80, a CD marker that occurs on antigen presenting cells such as activated B cells and monocytes that provides a co-stimulatory signal necessary for T cell activation and survival.
35781	CD86 biosynthetic process	P	The chemical reactions and pathways resulting in the formation of CD86, a CD marker that occurs on antigen presenting cells that provides co-stimulatory signals necessary for T cell activation and survival.
35782	mature natural killer cell chemotaxis	P	The directed movement of a mature natural killer cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis). A mature natural killer cell is a natural killer cell that is developmentally mature and expresses a variety of inhibitory and activating receptors that recognize MHC class and other stress related molecules.
35783	CD4-positive, alpha-beta T cell costimulation	P	The process of providing, via surface-bound receptor-ligand pairs, a second, antigen-independent, signal in addition to that provided by the T cell receptor to augment CD4-positive, alpha-beta T cell activation.
35784	nickel cation homeostasis	P	Any process involved in the maintenance of an internal steady state of nickel cations within an organism or cell.
35785	cellular nickel ion homeostasis	P	Any process involved in the maintenance of an internal steady state of nickel ions at the level of a cell.
35786	protein complex oligomerization	P	The association of two or more multisubunit protein complexes to form dimers or other multimers of a protein complex.
35787	cell migration involved in kidney development	P	The orderly movement of a cell from one site to another that will contribute to the progression of the kidney over time, from its formation to the mature organ.
35788	cell migration involved in metanephros development	P	The orderly movement of a cell from one site to another that will contribute to the progression of the metanephric kidney over time, from its formation to the mature organ.
35789	metanephric mesenchymal cell migration	P	The orderly movement of undifferentiated metanephric mesenchymal cells (precursors to metanephric mesangial cells) from the mesenchyme into the cleft of the developing glomerulus, during development of the metanephros.
35790	platelet-derived growth factor receptor-alpha signaling pathway	P	A series of molecular signals initiated by the binding of a ligand to an alpha-type platelet-derived growth factor receptor (PDGFalpha) on the surface of a signal-receiving cell, and ending with regulation of a downstream cellular process, e.g. transcription.
35791	platelet-derived growth factor receptor-beta signaling pathway	P	A series of molecular signals initiated by the binding of a ligand to a beta-type platelet-derived growth factor receptor (PDGFbeta) on the surface of a signal-receiving cell, and ending with regulation of a downstream cellular process, e.g. transcription.
35792	other organism postsynaptic membrane	C	A postsynaptic membrane that is part of another organism, i.e. a secondary organism with which the first organism is interacting. A postsynaptic membrane is a specialized area of membrane facing the presynaptic membrane on the tip of the nerve ending and separated from it by a minute cleft (the synaptic cleft). Neurotransmitters transmit the signal across the synaptic cleft to the postsynaptic membrane.
35793	positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway	P	Any process that increases the frequency, rate or extent of metanephric mesenchymal cell migration as a result of the series of molecular signals generated as a consequence of a platelet-derived growth factor receptor-beta binding to one of its physiological ligands.
35794	positive regulation of mitochondrial membrane permeability	P	Any process that increases the frequency, rate or extent of the passage or uptake of molecules by the mitochondrial membrane.
35795	negative regulation of mitochondrial membrane permeability	P	Any process that decreases the frequency, rate or extent of the passage or uptake of molecules by the mitochondrial membrane.
35796	ATP-binding cassette (ABC) transporter complex, transmembrane substrate-binding subunit-containing	C	A complex for the transport of metabolites into the cell, consisting of 4 subunits: a transmembrane substrate-binding protein (known as the S component), and an energy-coupling module that comprises two ATP-binding proteins (known as the A and A' components) and a transmembrane protein (known as the T component). Transport of the substrate across the membrane is driven by the hydrolysis of ATP.
35797	tellurite methyltransferase activity	F	Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to tellurite [TeO3(2-)]. Methylated derivatives of tellurite include Te(CH3)2 (dimethyltelluride) and Te2(CH3)2 (dimethylditelluride).
35798	2-alkenal reductase (NADP+) activity	F	Catalysis of the reaction: n-alkanal + NADP+ = alk-2-enal + NADPH + H+.
35799	ureter maturation	P	A developmental process, independent of morphogenetic (shape) change, that is required for the ureter to attain its fully functional state. The ureter is a muscular tube that transports urine from the kidney to the urinary bladder or from the Malpighian tubule to the hindgut.
35800	deubiquitinase activator activity	F	Increases the activity of deubiquitinase, an enzyme that catalyzes the hydrolysis of various forms of polymeric ubiquitin sequences.
35801	adrenal cortex development	P	The process whose specific outcome is the progression of the adrenal cortex over time, from its formation to the mature structure. The adrenal cortex is located at the periphery of the adrenal gland and controls glucose and electrolyte metabolism, response to stress and sexual development through the production of different classes of steroid hormones (glucocorticoids, mineralocorticoids and androgens).
35802	adrenal cortex formation	P	The process that gives rise to the adrenal cortex. This process pertains to the initial formation of a structure from unspecified parts. The adrenogonadal primordium from which the adrenal cortex is formed derives from a condensation of coelomic epithelial cells (the urogenital ridge; the same structure from which gonads and kidney also originate).
35803	egg coat formation	P	Construction of an egg coat, a specialized extracellular matrix that surrounds the ovum of animals. The egg coat provides structural support and can play an essential role in oogenesis, fertilization and early development.
35804	structural constituent of egg coat	F	The action of a molecule that contributes to the structural integrity of an egg coat. An egg coat is a specialized extracellular matrix that surrounds the ovum of animals. The egg coat provides structural support and can play an essential role in oogenesis, fertilization and early development.
35805	egg coat	C	A specialized extracellular matrix that surrounds the plasma membrane of the ovum of animals. The egg coat provides structural support and can play an essential role in oogenesis, fertilization and early development.
35806	modulation of blood coagulation in other organism	P	Any process in which an organism modulates the frequency, rate or extent of blood coagulation in another organism. Blood coagulation is the sequential process in which the multiple coagulation factors of the blood interact, ultimately resulting in the formation of an insoluble fibrin clot.
35807	positive regulation of blood coagulation in other organism	P	Any process in which an organism activates, maintains or increases the frequency, rate or extent of blood coagulation in another organism. Blood coagulation is the sequential process in which the multiple coagulation factors of the blood interact, ultimately resulting in the formation of an insoluble fibrin clot.
35808	meiotic recombination initiation complex	C	A protein complex that initiates the formation of double-strand breaks (DSBs) required for meiotic recombination. Consists of a protein that catalyses formation of the double-strand breaks (Spo11 in S. cerevisiae and Rec12 in S. pombe), and a number of accessory proteins.
35809	regulation of urine volume	P	Any process that modulates the amount of urine excreted from the body over a unit of time.
35810	positive regulation of urine volume	P	Any process that increases the amount of urine excreted from the body over a unit of time.
35811	negative regulation of urine volume	P	Any process that decreases the amount of urine excreted from the body over a unit of time.
35812	renal sodium excretion	P	The elimination by an organism of sodium in the urine.
35813	regulation of renal sodium excretion	P	Any process that modulates the amount of sodium excreted in urine over a unit of time.
35814	negative regulation of renal sodium excretion	P	Any process that decreases the amount of sodium excreted in urine over a unit of time.
35815	positive regulation of renal sodium excretion	P	Any process that increases the amount of sodium excreted in urine over a unit of time.
35816	renal water absorption involved in negative regulation of urine volume	P	Any process where water is taken up from the collecting ducts and proximal and distal loops of the nephron, which acts to decrease the amount of urine that is excreted from the body per unit time.
35817	renal sodium ion absorption involved in negative regulation of renal sodium excretion	P	Any process where sodium ions are taken up from the collecting ducts and proximal and distal loops of the nephron, which contributes to decreasing the amount of sodium that is excreted in urine per unit time.
35818	positive regulation of urine volume by pressure natriuresis	P	An increase in the amount of urine excreted over a unit of time, as a result of pressure natriuresis.
35819	positive regulation of renal sodium excretion by pressure natriuresis	P	An increase in the amount of sodium excreted in urine over a unit of time, as a result of pressure natriuresis.
35820	negative regulation of renal sodium excretion by angiotensin	P	The process in which angiotensin decreases the amount of sodium that is excreted in urine over a unit of time.
35821	modification of morphology or physiology of other organism	P	The process in which an organism effects a change in the structure or processes of a second organism.
35822	gene conversion	P	A DNA recombination process that results in the unidirectional transfer of genetic material from a donor sequence to a highly homologous acceptor.
35823	short tract gene conversion	P	A gene conversion process in which a segment of about 50-200 base pairs is transferred from the donor to the acceptor.
35824	long tract gene conversion	P	A gene conversion process in which a segment of more than 1000 base pairs is transferred from the donor to the acceptor.
35825	reciprocal DNA recombination	P	A DNA recombination process that results in the equal exchange of genetic material between the recombining DNA molecules.
35826	rubidium ion transport	P	The directed movement of rubidium ions (Rb+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
35827	rubidium ion transmembrane transporter activity	F	Enables the transfer of rubidium ions (Rb+) from one side of a membrane to the other.
35828	renal rubidium ion transport	P	The directed movement of rubidium ions (Rb+) by the kidney.
35829	renal rubidium ion absorption	P	A renal system process in which rubidium ions are taken up from the collecting ducts and proximal and distal loops of the nephron. In non-mammalian species, absorption may occur in related structures.
35830	palmatine metabolic process	P	The chemical reactions and pathways involving palmatine, a berberine alkaloid found in many plants.
35831	palmatine biosynthetic process	P	The chemical reactions and pathways resulting in the formation of palmatine, a berberine alkaloid found in many plants.
35832	berbamunine metabolic process	P	The chemical reactions and pathways involving berbamunine, an isoquinoline alkaloid.
35833	berbamunine biosynthetic process	P	The chemical reactions and pathways resulting in the formation of berbamunine, an isoquinoline alkaloid.
35834	indole alkaloid metabolic process	P	The chemical reactions and pathways involving an indole alkaloid, an alkaloid containing an indole skeleton.
35835	indole alkaloid biosynthetic process	P	The chemical reactions and pathways resulting in the formation of an indole alkaloid, an alkaloid containing an indole skeleton.
35836	ergot alkaloid metabolic process	P	The chemical reactions and pathways involving an ergot alkaloid, an indole alkaloid.
35837	ergot alkaloid biosynthetic process	P	The chemical reactions and pathways resulting in the formation of an ergot alkaloid.
35838	growing cell tip	C	The region at either end of the longest axis of a cylindrical or elongated cell, where polarized growth occurs.
35839	non-growing cell tip	C	A cell tip at which no growth takes place. For example, in fission yeast the cell end newly formed by cell division does not grow immediately upon its formation, and lacks actin cytoskeletal structures.
35840	old growing cell tip	C	A cell tip which has existed for at least one complete cell cycle, and at which polarized growth occurs. For example, in fission yeast the cell end that existed prior to cell division grows immediately after division, and contains a distinctive complement of proteins including actin cytoskeletal structures.
35841	new growing cell tip	C	A cell tip that was newly formed at the last cell division, and that has started to grow after the cell has activated bipolar cell growth (i.e. in which new end take-off, NETO, has taken place). New end take-off is when monopolar cells initiate bipolar growth.
35842	old cell tip after activation of bipolar cell growth	C	A cell tip which has existed for at least one complete cell cycle, and at which polarized growth occurs, which is part of a cell that has activated bipolar cell growth (i.e. in which new end take-off, NETO, has taken place). For example, in fission yeast the cell end that existed prior to cell division grows immediately after division, and contains a distinctive complement of proteins including actin cytoskeletal structures.
35843	endonuclear canal	C	A membrane-bound structure present in the nucleus of a spermatozoon. There is variation in the number of endonuclear canals between sperm of different organisms, and some species lack these structures altogether. The endonuclear canal may provide a supporting role for the sperm nucleus, and originates during spermiogenesis from an invagination of the nuclear envelope.
35844	cloaca development	P	The process whose specific outcome is the progression of the cloaca over time, from it's formation to the mature structure. The cloaca is the common chamber into which intestinal, genital and urinary canals open in vertebrates.
35845	photoreceptor cell outer segment organization	P	A process that is carried out at the cellular level and results in the assembly, arrangement of constituent parts, or disassembly of the outer segment of a photoreceptor cell, a sensory cell that reacts to the presence of light. The outer segment of the photoreceptor cell contains the light-absorbing materials.
35846	oviduct epithelium development	P	The progression of the oviduct epithelium over time from its initial formation to the mature structure. An oviduct is a tube through which an ova passes from the ovary to the uterus, or from the ovary to the outside of the organism. The oviduct epithelium is the specialized epithelium that lines the oviduct.
35847	uterine epithelium development	P	The progression of an epithelium of the uterus over time from its initial formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure.
35848	oviduct morphogenesis	P	The process in which anatomical structures of the oviduct are generated and organized. An oviduct is a tube through which an ova passes from the ovary to the uterus, or from the ovary to the outside of the organism.
35849	nephric duct elongation	P	The process in which the nephric duct grows along its axis. A nephric duct is a tube that drains a primitive kidney.
35850	epithelial cell differentiation involved in kidney development	P	The process in which relatively unspecialized cells acquire specialized structural and/or functional features of an epithelial cell that characterize the cells of the kidney as it progresses from its formation to the mature state.
35851	Krueppel-associated box domain binding	F	Interacting selectively and non-covalently with a Krueppel-associated box (KRAB) domain of a protein. The approximately 75 amino acid KRAB domain is enriched in charged amino acids, and is found in the N-terminal regions of many zinc finger-containing transcription factors.
35852	horizontal cell localization	P	Any process in which a horizontal cell is transported to, and/or maintained in, a specific location within the inner nuclear layer (INL) of the retina. A horizontal cell is a neuron that laterally connects other neurons in the inner nuclear layer (INL) of the retina. Targeting of retinal neurons to the appropriate lamina is vital to establish the architecture of the retina.
35853	chromosome passenger complex localization to spindle midzone	P	A cellular protein complex localization that acts on a chromosome passenger complex; as a result, the complex is transported to, or maintained in, a specific location at the spindle midzone. A chromosome passenger complex is a protein complex that contains the BIR-domain-containing protein Survivin, Aurora B kinase, INCENP and Borealin, and coordinates various events based on its location to different structures during the course of mitosis. The spindle midzone is the area in the center of the spindle where the spindle microtubules from opposite poles overlap.
35854	eosinophil fate commitment	P	The process in which the developmental fate of a cell becomes restricted such that it will develop into a eosinophil cell. A eosinophil is any of the immature or mature forms of a granular leukocyte with a nucleus that usually has two lobes connected by one or more slender threads of chromatin, and cytoplasm containing coarse, round granules that are uniform in size and which can be stained by the dye eosin.
35855	megakaryocyte development	P	The process whose specific outcome is the progression of a megakaryocyte cell over time, from its formation to the mature structure. Megakaryocyte development does not include the steps involved in committing a cell to a megakaryocyte fate. A megakaryocyte is a giant cell 50 to 100 micron in diameter, with a greatly lobulated nucleus, found in the bone marrow.
35857	eosinophil fate specification	P	The process involved in the specification of identity of an eosinophil cell. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment.
35858	eosinophil fate determination	P	The cell fate determination process in which a cell becomes capable of differentiating autonomously into an eosinophil cell regardless of its environment; upon determination, the cell fate cannot be reversed.
35859	Seh1-associated complex	C	A protein complex that associates dynamically with the vacuolar membrane, and is proposed to have a role in membrane-associated trafficking or regulatory processes. In S. cerevisiae the complex contains Seh1p, Sec13p, Npr2p, Npr3p, Iml1p, Mtc5p, Rtc1p, and Sea4p.
35860	glial cell-derived neurotrophic factor receptor signaling pathway	P	The series of molecular signals generated as a consequence of a glial cell-derived neurotrophic factor receptor binding to one of its physiological ligands.
35861	site of double-strand break	C	A region of a chromosome at which a DNA double-strand break has occurred. DNA damage signaling and repair proteins accumulate at the lesion to respond to the damage and repair the DNA to form a continuous DNA helix.
35862	dITP metabolic process	P	The chemical reactions and pathways involving dITP (deoxyinosine triphosphate (2'-deoxyinosine 5'-triphosphate). dITP is a deoxyinosine phosphate compound having a triphosphate group at the 5'-position.
35863	dITP catabolic process	P	The chemical reactions and pathways resulting in the breakdown of dITP, a deoxyinosine phosphate compound having a triphosphate group at the 5'-position.
35864	response to potassium ion	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a potassium ion stimulus.
35865	cellular response to potassium ion	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a potassium ion stimulus.
35866	alphav-beta3 integrin-PKCalpha complex	C	A protein complex that consists of an alphav-beta3 integrin complex bound to protein kinase C alpha.
35867	alphav-beta3 integrin-IGF-1-IGF1R complex	C	A protein complex that consists of an alphav-beta3 integrin complex bound to insulin-like growth factor-1 (IGF-1) and type I insulin-like growth factor receptor (IGF1R). IGF1R is a heterotetramer that consists of two alpha-subunits and two beta-subunits.
35868	alphav-beta3 integrin-HMGB1 complex	C	A protein complex that consists of an alphav-beta3 integrin complex bound to high mobility group box 1 protein.
35869	ciliary transition zone	C	A region of the cilium between the basal body and proximal segment that is characterized by Y-shaped assemblages that connect axonemal microtubules to the ciliary membrane. The ciliary transition zone appears to function as a gate that controls ciliary membrane composition and separates the cytosol from the ciliary plasm.
35870	dITP diphosphatase activity	F	Catalysis of the reaction: dITP + H2O = dIMP + diphosphate.
35871	protein K11-linked deubiquitination	P	A protein deubiquitination process in which a K11-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 11 of the ubiquitin monomers, is removed from a protein.
35872	nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway	P	A series of molecular signals generated as a consequence of a nucleotide-binding domain, leucine rich repeat containing receptor (NLR) binding to one of its physiological ligands. NLRs are cytoplasmic receptors defined by their tripartite domain architecture that contains: a variable C-terminus, a middle nucleotide-binding domain, and a LRR domain that is variable in the repeats composition and number. The NLR signaling pathway begins with binding of a ligand to a NLR receptor and ends with regulation of a downstream cellular process.
35873	lactate transmembrane transport	P	The directed movement of lactate across a membrane by means of some agent such as a transporter or pore. Lactate is 2-hydroxypropanoate, CH3-CHOH-COOH; L(+)-lactate is formed by anaerobic glycolysis in animal tissues, and DL-lactate is found in sour milk, molasses and certain fruit juices.
35874	cellular response to copper ion starvation	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of copper ions.
35875	maintenance of meiotic sister chromatid cohesion, centromeric	P	The process in which the association between sister chromatids of a replicated chromosome along the length of the centromeric region is maintained as chromosomes condense, attach to the spindle in a bipolar orientation, and congress to the metaphase plate during a meiotic cell cycle.
35876	maintenance of meiotic sister chromatid cohesion, arms	P	The process in which the association between sister chromatids of a replicated chromosome along the length of the chromosome arms, is maintained as chromosomes condense, attach to the spindle in a bipolar orientation, and congress to the metaphase plate during a meiotic cell cycle.
35877	death effector domain binding	F	Interacting selectively and non-covalently with a DED domain (death effector domain) of a protein, a homotypic protein interaction module composed of a bundle of six alpha-helices that is related in structure to the death domain (DD).
35878	nail development	P	The process whose specific outcome is the progression of a nail over time, from its formation to the mature structure. A nail is a horn-like envelope covering the outer end of a finger or toe, and consists of the nail plate, the nail matrix and the nail bed below it, and the grooves surrounding it.
35879	plasma membrane lactate transport	P	The directed movement of lactate across a plasma membrane.
35880	embryonic nail plate morphogenesis	P	The process, occurring in the embryo, by which the anatomical structures of a nail plate are generated and organized. The nail plate is the hard and translucent portion of the nail, composed of keratin, and serves to protect the tips of digits.
35881	amacrine cell differentiation	P	The process in which a relatively unspecialized cell acquires specialized features of an amacrine cell, an interneuron generated in the inner nuclear layer (INL) of the vertebrate retina. Amacrine cells integrate, modulate, and interpose a temporal domain in the visual message presented to the retinal ganglion cells, with which they synapse in the inner plexiform layer. Amacrine cells lack large axons.
35882	defecation rhythm	P	The rhythmic process of defecation that consists of an intestinal oscillator which regulates calcium waves. These waves in turn control a stereotypical, three-part pattern of muscle contractions. In some organisms, defecation can recur with a regularity more frequent than every 24 hours. For example, in a well-fed Caenorhabditis elegans, the defecation motor program occurs approximately every 45 seconds, and is temperature- and touch-compensated.
35883	enteroendocrine cell differentiation	P	The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of an enteroendocrine cell. Enteroendocrine cells are hormonally active epithelial cells in the gut that constitute the diffuse neuroendocrine system.
35884	arabinan biosynthetic process	P	The chemical reactions and pathways resulting in the formation of arabinan, a polysaccharide composed of arabinose residues.
35885	exochitinase activity	F	Catalysis of the hydrolysis of terminal 1,4-beta-linkages of N-acetyl-D-glucosamine (GlcNAc) polymers of chitin and chitodextrins. Typically, exochitinases progressively cleave off two subunits from the reducing or non-reducing ends of the chitin chain.
35886	vascular smooth muscle cell differentiation	P	The process in which a relatively unspecialized cell acquires specialized features of a vascular smooth muscle cell.
35887	aortic smooth muscle cell differentiation	P	The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell surrounding the aorta.
35888	isoguanine deaminase activity	F	Catalysis of the reaction: isoguanine + H2O = xanthine + NH3.
35889	otolith tethering	P	The attachment of a developing otolith to the kinocilia of tether cells in the inner ear.
35890	exit from host	P	The directed movement of an organism out of the body, tissues or cells of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
35891	exit from host cell	P	The directed movement of an organism out of a cell of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
35892	modulation of platelet aggregation in other organism	P	Any process in which an organism modulates the frequency, rate or extent of platelet aggregation in another organism. Platelet aggregation is the adhesion of one platelet to one or more other platelets via adhesion molecules.
35893	negative regulation of platelet aggregation in other organism	P	Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of platelet aggregation in a second organism.
35894	positive regulation of platelet aggregation in other organism	P	Any process in which an organism activates, maintains or increases the frequency, rate or extent of platelet aggregation in another organism.
35895	modulation of mast cell degranulation in other organism	P	Any process in which an organism modulates the frequency, rate or extent of blood mast cell degranulation in another organism. Mast cell degranulation is the regulated exocytosis of secretory granules containing preformed mediators such as histamine, serotonin, and neutral proteases by a mast cell.
35896	positive regulation of mast cell degranulation in other organism	P	Any process in which an organism increases the frequency, rate or extent of blood mast cell degranulation in another organism.
35897	proteolysis in other organism	P	The chemical reactions and pathways performed by an organism resulting in the hydrolysis of proteins in another organism by cleavage of their peptide bonds.
35898	parathyroid hormone secretion	P	The regulated release of parathyroid hormone into the circulatory system.
35899	negative regulation of blood coagulation in other organism	P	Any process in which an organism stops, prevents or reduces the frequency, rate or extent of blood coagulation in another organism. Blood coagulation is the sequential process in which the multiple coagulation factors of the blood interact, ultimately resulting in the formation of an insoluble fibrin clot.
35900	response to isolation stress	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lack of contact with other members of the same species.
35901	cellular response to isolation stress	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lack of contact with other members of the same species.
35902	response to immobilization stress	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of being rendered immobile.
35903	cellular response to immobilization stress	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of being rendered immobile.
35904	aorta development	P	The progression of the aorta over time, from its initial formation to the mature structure. An aorta is an artery that carries blood from the heart to other parts of the body.
35905	ascending aorta development	P	The progression of the ascending aorta over time, from its initial formation to the mature structure. The ascending aorta is the portion of the aorta in a two-pass circulatory system that lies between the heart and the arch of aorta. In a two-pass circulatory system blood passes twice through the heart to supply the body once.
35906	descending aorta development	P	The progression of the descending aorta over time, from its initial formation to the mature structure. The descending aorta is the portion of the aorta in a two-pass circulatory system from the arch of aorta to the point where it divides into the common iliac arteries. In a two-pass circulatory system blood passes twice through the heart to supply the body once.
35907	dorsal aorta development	P	The progression of the dorsal aorta over time, from its initial formation to the mature structure. The dorsal aorta is a blood vessel in a single-pass circulatory system that carries oxygenated blood from the gills to the rest of the body. In a single-pass circulatory system blood passes once through the heart to supply the body once.
35908	ventral aorta development	P	The progression of the ventral aorta over time, from its initial formation to the mature structure. The ventral aorta is a blood vessel in a single-pass circulatory system that carries de-oxygenated blood from the heart to the gills. In a single-pass circulatory system blood passes once through the heart to supply the body once.
35909	aorta morphogenesis	P	The process in which the anatomical structures of an aorta are generated and organized. An aorta is an artery that carries blood from the heart to other parts of the body.
35910	ascending aorta morphogenesis	P	The process in which the anatomical structures of the ascending aorta are generated and organized. The ascending aorta is the portion of the aorta in a two-pass circulatory system that lies between the heart and the arch of aorta. In a two-pass circulatory system blood passes twice through the heart to supply the body once.
35911	descending aorta morphogenesis	P	The process in which the anatomical structures of the descending aorta are generated and organized. The descending aorta is the portion of the aorta in a two-pass circulatory system from the arch of aorta to the point where it divides into the common iliac arteries. In a two-pass circulatory system blood passes twice through the heart to supply the body once.
35912	dorsal aorta morphogenesis	P	The process in which the anatomical structures of the dorsal aorta are generated and organized. The dorsal aorta is a blood vessel in a single-pass circulatory system that carries oxygenated blood from the gills to the rest of the body. In a single-pass circulatory system blood passes once through the heart to supply the body once.
35913	ventral aorta morphogenesis	P	The process in which the anatomical structures of the ventral aorta are generated and organized. The ventral aorta is a blood vessel in a single-pass circulatory system that carries de-oxygenated blood from the heart to the gills. In a single-pass circulatory system blood passes once through the heart to supply the body once.
35914	skeletal muscle cell differentiation	P	The process in which a relatively unspecialized cell acquires specialized features of a skeletal muscle cell, a somatic cell located in skeletal muscle.
35915	pore formation in membrane of other organism	P	The aggregation, arrangement and bonding together of a set of components by an organism to form a pore complex in a membrane of another organism.
35916	modulation of calcium channel activity in other organism	P	Any process in which an organism effects a change in the frequency, rate or extent of the activity of a calcium channel in another organism.
35917	negative regulation of calcium channel activity in other organism	P	Any process in which an organism stops, prevents or reduces the frequency, rate or extent of the activity of a calcium channel in another organism.
35918	negative regulation of voltage-gated calcium channel activity in other organism	P	Any process in which an organism stops, prevents or reduces the frequency, rate or extent of the activity of a voltage-gated calcium channel in another organism. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.
35919	negative regulation of low voltage-gated calcium channel activity in other organism	P	Any process in which an organism stops, prevents or reduces the frequency, rate or extent of the activity of a low voltage-gated calcium channel in another organism. A low voltage-gated channel is a channel whose open state is dependent on low voltage across the membrane in which it is embedded.
35920	negative regulation of high voltage-gated calcium channel activity in other organism	P	Any process in which an organism stops, prevents or reduces the frequency, rate or extent of the activity of a high voltage-gated calcium channel in another organism. A high voltage-gated channel is a channel whose open state is dependent on high voltage across the membrane in which it is embedded.
35921	desmosome disassembly	P	The controlled breakdown of a desmosome. A desmosome is a patch-like intercellular junction found in vertebrate tissues, consisting of parallel zones of two cell membranes, separated by an space of 25-35 nm, and having dense fibrillar plaques in the subjacent cytoplasm.
35922	foramen ovale closure	P	The morphogenetic process in which the foramen ovale closes after birth, to prevent blood flow between the right and left atria. In the fetal heart, the foramen ovale allows blood to enter the left atrium from the right atrium. Closure of the foramen ovale after birth stops this blood flow.
35923	flurbiprofen binding	F	Interacting selectively and non-covalently with flurbiprofen.
35924	cellular response to vascular endothelial growth factor stimulus	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vascular endothelial growth factor stimulus.
35925	mRNA 3'-UTR AU-rich region binding	F	Interacting selectively and non-covalently with a region containing frequent adenine and uridine bases within the 3' untranslated region of a mRNA molecule.
35926	chemokine (C-C motif) ligand 2 secretion	P	The regulated release of chemokine (C-C motif) ligand 2 (CCL2) from a cell.
35927	RNA import into mitochondrion	P	The directed movement of RNA from the cytoplasm into a mitochondrion.
35928	rRNA import into mitochondrion	P	The directed movement of rRNA, ribosomal ribonucleic acid, from the cytoplasm into a mitochondrion.
35929	steroid hormone secretion	P	The regulated release of any steroid that acts as a hormone into the circulatory system.
35930	corticosteroid hormone secretion	P	The regulated release of any corticosteroid hormone into the circulatory system.
35931	mineralocorticoid secretion	P	The regulated release of any mineralocorticoid into the circulatory system. Mineralocorticoids are a class of steroid hormones that regulate water and electrolyte metabolism.
35932	aldosterone secretion	P	The regulated release of aldosterone into the circulatory system. Aldosterone is a pregnane-based steroid hormone produced by the outer-section (zona glomerulosa) of the adrenal cortex in the adrenal gland, and acts on the distal tubules and collecting ducts of the kidney to cause the conservation of sodium, secretion of potassium, increased water retention, and increased blood pressure. The overall effect of aldosterone is to increase reabsorption of ions and water in the kidney.
35933	glucocorticoid secretion	P	The regulated release of any glucocorticoid hormone into the circulatory system. Glucocorticoids are a class of steroid hormones that regulate a variety of physiological processes, in particular control of the concentration of glucose in blood.
35934	corticosterone secretion	P	The regulated release of corticosterone into the circulatory system. Corticosterone is a 21-carbon steroid hormone of the corticosteroid type produced in the cortex of the adrenal glands.
35935	androgen secretion	P	The regulated release of an androgen into the circulatory system. Androgens are steroid hormones that stimulate or control the development and maintenance of masculine characteristics in vertebrates.
35936	testosterone secretion	P	The regulated release of testosterone into the circulatory system. Testosterone is an androgen having 17beta-hydroxy and 3-oxo groups, together with unsaturation at C-4-C-5.
35937	estrogen secretion	P	The regulated release of estrogen into the circulatory system. Estrogen is a steroid hormone that stimulates or controls the development and maintenance of female sex characteristics in mammals.
35938	estradiol secretion	P	The regulated release of estradiol into the circulatory system.
35939	microsatellite binding	F	Interacting selectively and non-covalently with a microsatellite, a repeat_region in DNA containing repeat units (2 to 4 base pairs) that is repeated multiple times in tandem.
35940	negative regulation of peptidase activity in other organism	P	Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of peptidase activity, the catalysis of the hydrolysis of peptide bonds in a protein, in a second organism.
35941	androstenedione secretion	P	The regulated release of androstenedione (androst-4-ene-3,17-dione) into the circulatory system.
35942	dehydroepiandrosterone secretion	P	The regulated release of dehydroepiandrosterone (3beta-hydroxyandrost-5-en-17-one) into the circulatory system.
35943	estrone secretion	P	The regulated release of estrone into the circulatory system.
35944	perforin production	P	The appearance of a perforin protein due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
35945	mitochondrial ncRNA surveillance	P	The set of processes involved in identifying and degrading defective or aberrant non-coding RNA transcripts (ncRNAs) within the mitochondrion.
35946	mitochondrial mRNA surveillance	P	The set of processes involved in identifying and degrading messenger RNA (mRNA) within the mitochondrion.
35947	regulation of gluconeogenesis by regulation of transcription from RNA polymerase II promoter	P	Any process that modulates the frequency, rate or extent of gluconeogenesis, by regulation of transcription from an RNA polymerase II promoter.
35948	positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter	P	Any process that activates or increases the frequency, rate or extent of gluconeogenesis by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter.
35949	positive regulation of gluconeogenesis by negative regulation of transcription from RNA polymerase II promoter	P	Any process that activates or increases the frequency, rate or extent of gluconeogenesis by stopping, preventing, or reducing the frequency, rate or extent of transcription from an RNA polymerase II promoter.
35950	regulation of oligopeptide transport by regulation of transcription from RNA polymerase II promoter	P	Any process that modulates the frequency, rate or extent of oligopeptide transport, by regulation of transcription from an RNA polymerase II promoter.
35951	positive regulation of oligopeptide transport by positive regulation of transcription from RNA polymerase II promoter	P	Any process that activates or increases the frequency, rate or extent of oligopeptide transport by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter.
35952	negative regulation of oligopeptide transport by negative regulation of transcription from RNA polymerase II promoter	P	Any process that stops, prevents or reduces the frequency, rate or extent of oligopeptide transport by stopping, preventing or reducing the frequency, rate or extent of transcription from an RNA polymerase II promoter.
35953	regulation of dipeptide transport by regulation of transcription from RNA polymerase II promoter	P	Any process that modulates the frequency, rate or extent of dipeptide transport, by regulation of transcription from an RNA polymerase II promoter.
35954	positive regulation of dipeptide transport by positive regulation of transcription from RNA polymerase II promoter	P	Any process that activates or increases the frequency, rate or extent of dipeptide transport by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter.
35955	negative regulation of dipeptide transport by negative regulation of transcription from RNA polymerase II promoter	P	Any process that stops, prevents or reduces the frequency, rate or extent of dipeptide transport by stopping, preventing or reducing the frequency, rate or extent of transcription from an RNA polymerase II promoter.
35956	regulation of starch catabolic process by regulation of transcription from RNA polymerase II promoter	P	Any process that modulates the frequency, rate or extent of the breakdown of starch, by modulating the frequency, rate or extent of transcription from an RNA polymerase II promoter.
35957	positive regulation of starch catabolic process by positive regulation of transcription from RNA polymerase II promoter	P	Any process that activates or increases the frequency, rate or extent of the breakdown of starch, by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter.
35958	regulation of glyoxylate cycle by regulation of transcription from RNA polymerase II promoter	P	Any process that modulates the frequency, rate or extent of the glyoxylate cycle by modulating the frequency, rate or extent of transcription from an RNA polymerase II promoter.
35959	positive regulation of glyoxylate cycle by positive regulation of transcription from RNA polymerase II promoter	P	Any process that activates or increases the frequency, rate or extent of the glyoxylate cycle by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter.
35960	regulation of ergosterol biosynthetic process by regulation of transcription from RNA polymerase II promoter	P	Any process that modulates the frequency, rate or extent of ergosterol biosynthetic process by modulating the frequency, rate or extent of transcription from an RNA polymerase II promoter.
35961	positive regulation of ergosterol biosynthetic process by positive regulation of transcription from RNA polymerase II promoter	P	Any process that activates or increases the frequency, rate or extent of ergosterol biosynthesis by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter.
35962	response to interleukin-13	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-13 stimulus.
35963	cellular response to interleukin-13	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-13 stimulus.
35964	COPI-coated vesicle budding	P	The evagination of a Golgi membrane, resulting in formation of a COPI-coated vesicle.
35965	cardiolipin acyl-chain remodeling	P	Remodeling the acyl chains of premature (de novo synthesized) cardiolipin (1,3-bis(3-phosphatidyl)glycerol), through sequential deacylation and re-acylation reactions, to generate mature cardiolipin containing high-levels of unsaturated fatty acids.
35966	response to topologically incorrect protein	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a protein that is not folded in its correct three-dimensional structure.
35967	cellular response to topologically incorrect protein	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a protein that is not folded in its correct three-dimensional structure.
35968	regulation of sterol import by regulation of transcription from RNA polymerase II promoter	P	Any process that modulates the frequency, rate or extent of sterol import, by regulation of transcription from an RNA polymerase II promoter.
35969	positive regulation of sterol import by positive regulation of transcription from RNA polymerase II promoter	P	Any process that activates or increases the frequency, rate or extent of sterol import by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter.
35970	peptidyl-threonine dephosphorylation	P	The removal of phosphoric residues from peptidyl-O-phospho-L-threonine to form peptidyl-threonine.
35971	peptidyl-histidine dephosphorylation	P	The removal of phosphoric residues from peptidyl-O-phospho-L-histidine to form peptidyl-histidine.
35973	aggrephagy	P	Selective degradation of protein aggregates by macroautophagy.
35974	meiotic spindle pole body	C	The microtubule organizing center that forms as part of the meiotic cell cycle; functionally homologous to the animal cell centrosome.
35975	carbamoyl phosphate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of carbamoyl phosphate, an intermediate in the urea cycle and other nitrogen compound metabolic pathways.
35976	transcription factor AP-1 complex	C	A heterodimeric transcription factor complex composed of proteins from the c-Fos, c-Jun, activating transcription factor (ATF) or JDP families. The subunits contain a basic leucine zipper (bZIP) domain that is essential for dimerization and DNA binding. Jun-Fos heterodimers bind preferentially to a heptamer consensus sequence (TPA responsive element (TRE)), whereas Jun-ATF dimers bind the cyclic AMP responsive element (CRE) to regulate transcription of target genes.
35977	protein deglycosylation involved in glycoprotein catabolic process	P	The removal of sugar residues from a glycosylated protein that contributes to the breakdown of a glycoprotein.
35978	histone H2A-S139 phosphorylation	P	The modification of histone H2A by the addition of an phosphate group to a serine residue at position 139 of the histone.
35979	histone kinase activity (H2A-S139 specific)	F	Catalysis of the transfer of a phosphate group to the serine-139 residue of the C-terminal tail of histone H2A.
35981	tongue muscle cell differentiation	P	The process in which a relatively unspecialized cell acquires specialized features of a tongue muscle cell.
35983	response to trichostatin A	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a trichostatin A stimulus.
35984	cellular response to trichostatin A	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a trichostatin A stimulus.
35985	senescence-associated heterochromatin focus	C	A transcriptionally-silent heterochromatin structure present in senescent cells. Contains the condensed chromatin of one chromosome and is enriched for histone modifications. Thought to repress expression of proliferation-promoting genes.
35986	senescence-associated heterochromatin focus assembly	P	The assembly of chromatin into senescence-associated heterochromatin foci (SAHF), transcriptionally-silent heterochromatin structures present in senescent cells, containing the condensed chromatin of one chromosome, and enriched for histone modifications. Formation of these chromatin structures is thought to repress expression of proliferation-promoting genes.
35987	endodermal cell differentiation	P	The process in which a relatively unspecialized cell acquires the specialized features of an endoderm cell, a cell of the inner of the three germ layers of the embryo.
35988	chondrocyte proliferation	P	The multiplication or reproduction of chondrocytes by cell division, resulting in the expansion of their population. A chondrocyte is a polymorphic cell that forms cartilage.
35989	tendon development	P	The process whose specific outcome is the progression of a tendon over time, from its formation to the mature structure. A tendon is a fibrous, strong, connective tissue that connects muscle to bone or integument and is capable of withstanding tension. Tendons and muscles work together to exert a pulling force.
35990	tendon cell differentiation	P	The process in which a relatively unspecialized cell acquires the specialized features of a tendon cell. Tendon cell are elongated fibrocytes in which the cytoplasm is stretched between the collagen fibres of the tendon. Tendon cells have a central cell nucleus with a prominent nucleolus, a well-developed rough endoplasmic reticulum, and are responsible for synthesis and turnover of tendon fibres and ground substance.
35991	nitric oxide sensor activity	F	Interacting selectively and non-covalently with and responding, e.g. by conformational change, to changes in the cellular level of nitric oxide (NO).
35992	tendon formation	P	The process that gives rise to a tendon. This process pertains to the initial formation of a tendon from unspecified parts.
35993	deltoid tuberosity development	P	The process whose specific outcome is the progression of the deltoid tuberosity over time, from its formation to the mature structure. The deltoid tuberosity is the region on the shaft of the humerus to which the deltoid muscle attaches. The deltoid tuberosity develops through endochondral ossification in a two-phase process; an initiating tendon-dependent phase, and a muscle-dependent growth phase.
35994	response to muscle stretch	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a myofibril being extended beyond its slack length.
35995	detection of muscle stretch	P	The series of events by which a muscle stretch stimulus is received by a cell and converted into a molecular signal.
35996	rhabdomere microvillus	C	Thin cylindrical membrane-covered projection on the surface of a rhabdomere.
35997	rhabdomere microvillus membrane	C	The portion of the plasma membrane surrounding a microvillus of a rhabdomere.
35998	7,8-dihydroneopterin 3'-triphosphate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of 7,8-dihydroneopterin 3'-triphosphate.
35999	tetrahydrofolate interconversion	P	The chemical reactions and pathways by which one-carbon (C1) units are transferred between tetrahydrofolate molecules, to synthesise other tetrahydrofolate molecules.
36000	mucocyst	C	A small subcellular vesicle, surrounded by a membrane, in the pellicle of ciliate protozoans that discharges a mucus-like secretion.
36001	'de novo' pyridoxal 5'-phosphate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of pyridoxal 5'-phosphate, the active form of vitamin B6, from simpler components.
36002	pre-mRNA binding	F	Interacting selectively and non-covalently with pre-messenger RNA (pre-mRNA), an intermediate molecule between DNA and protein that may contain introns and, at least in part, encodes one or more proteins. Introns are removed from pre-mRNA to form a mRNA molecule.
36003	positive regulation of transcription from RNA polymerase II promoter in response to stress	P	Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).
36004	GAF domain binding	F	Interacting selectively and non-covalently with the GAF domain of a protein.
36005	response to macrophage colony-stimulating factor	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a macrophage colony-stimulating factor stimulus.
36006	cellular response to macrophage colony-stimulating factor stimulus	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a macrophage colony-stimulating factor stimulus.
36007	scintillon	C	A body present in the cytoplasm of some dinoflagellates, which is the source of bioluminescence; emits light on acidification in the presence of oxygen.
36008	sucrose catabolic process to fructose-6-phosphate and glucose-6-phosphate	P	The chemical reactions and pathways resulting in the breakdown of sucrose, which proceeds by phosphorylation of sucrose to form sucrose-6-phosphate. The subsequent actions of a hydrolase and a fructokinase generate fructose-6-phosphate and glucose-6-phosphate.
36009	protein-glutamine N-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + protein L-glutamine = S-adenosyl-L-homocysteine + protein N-methyl-L-glutamine.
36010	protein localization to endosome	P	A process in which a protein is transported to, or maintained in, a location within an endosome.
36011	imaginal disc-derived leg segmentation	P	Division of an imaginal disc-derived leg into a series of semi-repetitive parts or segments. The Drosophila leg, for example, has nine segments, each separated from the next by a flexible joint.
36012	cyanelle inner membrane	C	The inner, i.e. lumen-facing, lipid bilayer of the cyanelle envelope; also faces the cyanelle stroma.
36013	cyanelle outer membrane	C	The outer, i.e. cytoplasm-facing, lipid bilayer of the cyanelle envelope.
36014	cyanelle intermembrane space	C	The region between the inner and outer lipid bilayers of the cyanelle envelope; includes the peptidoglycan layer.
36015	response to interleukin-3	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-3 stimulus.
36016	cellular response to interleukin-3	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-3 stimulus.
36017	response to erythropoietin	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an erythropoietin stimulus. Erythropoietin is a glycoprotein hormone that controls erythropoiesis.
36018	cellular response to erythropoietin	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an erythropoietin stimulus.
36019	endolysosome	C	An transient hybrid organelle formed by fusion of a late endosome with a lysosome, and in which active degradation takes place.
36020	endolysosome membrane	C	The lipid bilayer surrounding an endolysosome. An endolysosome is a transient hybrid organelle formed by fusion of a late endosome with a lysosome.
36021	endolysosome lumen	C	The volume enclosed by the membrane of an endolysosome. An endolysosome is a transient hybrid organelle formed by fusion of a late endosome with a lysosome.
36022	limb joint morphogenesis	P	The process in which the anatomical structures of a limb joint are generated and organized. A limb joint is a flexible region that separates the rigid sections of a limb to allow movement in a controlled manner.
36023	embryonic skeletal limb joint morphogenesis	P	The process, occurring in the embryo, in which the anatomical structures of a skeletal limb joint are generated and organized. A skeletal limb joint is the connecting structure between the bones of a limb.
36024	protein C inhibitor-TMPRSS7 complex	C	A heterodimeric protein complex that contains protein C inhibitor (SERPINA5) and transmembrane protease serine 7 (TMPRSS7); formation of the complex inhibits the serine protease activity of transmembrane protease serine 7.
36025	protein C inhibitor-TMPRSS11E complex	C	A heterodimeric protein complex that contains protein C inhibitor (SERPINA5) and transmembrane protease serine 11E (TMPRSS11E); formation of the complex inhibits the serine protease activity of transmembrane protease serine 11E.
36026	protein C inhibitor-PLAT complex	C	A heterodimeric protein complex that contains protein C inhibitor (SERPINA5) and tissue-type plasminogen activator (PLAT); formation of the complex inhibits the serine protease activity of tissue-type plasminogen activator.
36027	protein C inhibitor-PLAU complex	C	A heterodimeric protein complex that contains protein C inhibitor (SERPINA5) and urokinase-type plasminogen activator (PLAU); formation of the complex inhibits the serine protease activity of urokinase-type plasminogen activator.
36028	protein C inhibitor-thrombin complex	C	A heterodimeric protein complex that contains protein C inhibitor (SERPINA5) and thrombin (F2); formation of the complex inhibits the serine protease activity of thrombin.
36029	protein C inhibitor-KLK3 complex	C	A heterodimeric protein complex that contains protein C inhibitor (SERPINA5) and prostate-specific antigen (KLK3); formation of the complex inhibits the serine protease activity of prostate-specific antigen.
36030	protein C inhibitor-plasma kallikrein complex	C	A heterodimeric protein complex that contains protein C inhibitor (SERPINA5) and plasma kallikrein (KLK1B); formation of the complex inhibits the serine protease activity of plasma kallikrein.
36031	recruitment of mRNA capping enzyme to RNA polymerase II holoenzyme complex	P	The process in which the guanylyltransferase enzyme responsible for adding a 7-methylguanosine cap on pre-mRNA becomes associated with the RNA polymerase II holoenzyme complex and the 5' end of a transcript.
36032	neural crest cell delamination	P	The negative regulation of cell adhesion process in which a neural crest cell physically separates from the rest of the neural tube.
36033	mediator complex binding	F	Interacting selectively and non-covalently with a mediator complex. The mediator complex is a protein complex that interacts with the carboxy-terminal domain of the largest subunit of RNA polymerase II and plays an active role in transducing the signal from a transcription factor to the transcriptional machinery. The Saccharomyces complex contains several identifiable subcomplexes: a head domain comprising Srb2, -4, and -5, Med6, -8, and -11, and Rox3 proteins; a middle domain comprising Med1, -4, and -7, Nut1 and -2, Cse2, Rgr1, Soh1, and Srb7 proteins; a tail consisting of Gal11p, Med2p, Pgd1p, and Sin4p; and a regulatory subcomplex comprising Ssn2, -3, and -8, and Srb8 proteins. Metazoan mediator complexes have similar modular structures and include homologs of yeast Srb and Med proteins.
36034	mediator complex assembly	P	The aggregation, arrangement and bonding together of a set of components to form a mediator complex. The mediator complex is a protein complex that interacts with the carboxy-terminal domain of the largest subunit of RNA polymerase II and plays an active role in transducing the signal from a transcription factor to the transcriptional machinery. The Saccharomyces complex contains several identifiable subcomplexes: a head domain comprising Srb2, -4, and -5, Med6, -8, and -11, and Rox3 proteins; a middle domain comprising Med1, -4, and -7, Nut1 and -2, Cse2, Rgr1, Soh1, and Srb7 proteins; a tail consisting of Gal11p, Med2p, Pgd1p, and Sin4p; and a regulatory subcomplex comprising Ssn2, -3, and -8, and Srb8 proteins. Metazoan mediator complexes have similar modular structures and include homologs of yeast Srb and Med proteins.
36035	osteoclast development	P	The process whose specific outcome is the progression of a osteoclast from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate. An osteoclast is a specialized phagocytic cell associated with the absorption and removal of the mineralized matrix of bone tissue.
36036	cardiac neural crest cell delamination	P	The negative regulation of cell adhesion process in which a cardiac neural crest cell physically separates from the rest of the neural tube.
36037	CD8-positive, alpha-beta T cell activation	P	The change in morphology and behavior of a CD8-positive, alpha-beta T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.
36038	MKS complex	C	A protein complex that is located at the ciliary transition zone and consists of several proteins some of which are membrane bound. Acts as an organiser of transition zone inner structure, specifically the Y-shaped links, in conjunction with the NPHP complex. The MKS complex also acts as part of the selective barrier that prevents diffusion of proteins between the ciliary cytoplasm and cellular cytoplasm as well as between the ciliary membrane and plasma membrane.
36039	curcumin metabolic process	P	The chemical reactions and pathways involving the polyphenol, curcumin.
36040	curcumin catabolic process	P	The chemical reactions and pathways resulting in the breakdown of the polyphenol, curcumin.
36041	long-chain fatty acid binding	F	Interacting selectively and non-covalently with a long-chain fatty acid. A long-chain fatty acid is a fatty acid with a chain length between C13 and C22.
36042	long-chain fatty acyl-CoA binding	F	Interacting selectively and non-covalently with a long-chain fatty acyl-CoA. A long-chain fatty acyl-CoA is any derivative of coenzyme A in which the sulfhydryl group is in a thioester linkage with a long-chain fatty-acyl group. Long-chain fatty-acyl-CoAs have chain lengths of C13 or more.
36046	protein demalonylation	P	The removal of a malonyl group (CO-CH2-CO), from an amino acid residue within a protein or peptide.
36047	peptidyl-lysine demalonylation	P	The process of removing a malonyl group (CO-CH2-CO) from an malonylated lysine residue in a peptide or protein.
36048	protein desuccinylation	P	The removal of a succinyl group (CO-CH2-CH2-CO) from a residue in a peptide or protein.
36049	peptidyl-lysine desuccinylation	P	The removal of a succinyl group (CO-CH2-CH2-CO) from a succinylated lysine residue in a peptide or protein.
36050	peptidyl-lysine succinylation	P	The modification of a peptidyl-lysine residue by the addition of a succinyl group (CO-CH2-CH2-CO) to form N6-succinyl-L-lysine.
36051	protein localization to trailing edge	P	A process in which a protein is transported to, or maintained at, the trailing edge. The trailing edge is the area of a motile cell opposite to the direction of movement.
36052	protein localization to uropod	P	A process in which a protein is transported to, or maintained in, a uropod. A uropod is a membrane projection with related cytoskeletal components at the trailing edge of a migrating cell.
36053	glomerular endothelium fenestra	C	A large plasma membrane-lined circular pore that perforates the flattened glomerular endothelium and, unlike those of other fenestrated capillaries, is not spanned by diaphragms; the density and size of glomerular fenestrae account, at least in part, for the high permeability of the glomerular capillary wall to water and small solutes.
36054	protein-malonyllysine demalonylase activity	F	Catalysis of the reaction: protein-malonyllysine + H2O => protein-lysine + malonate. This reaction is the removal of a malonyl group (CO-CH2-CO) from a malonylated lysine residue of a protein or peptide.
36055	protein-succinyllysine desuccinylase activity	F	Catalysis of the reaction: protein-succinyllysine + H2O => protein-lysine + succinate. This reaction is the removal of a succinyl group (CO-CH2-CH2-CO) from a succinylated lysine residue of a protein or peptide.
36056	filtration diaphragm	C	A specialized cell-cell junction found between the cells of the excretory system, which provides a barrier for filtration of blood or hemolymph.
36057	slit diaphragm	C	A specialized cell-cell junction found between the interdigitating foot processes of the glomerular epithelium (the podocytes) in the vertebrate kidney, which is adapted for facilitating glomerular filtration.
36058	filtration diaphragm assembly	P	The aggregation, arrangement and bonding together of a set of components to form a filtration diaphragm, a specialized cell-cell junction found between the cells of the excretory system, which provides a barrier for filtration of blood or hemolymph.
36059	nephrocyte diaphragm assembly	P	The aggregation, arrangement and bonding together of a set of components to form a nephrocyte diaphragm, a specialized cell-cell junction found between nephrocytes of the insect kidney.
36060	slit diaphragm assembly	P	The aggregation, arrangement and bonding together of a set of components to form a slit diaphragm, specialized cell-cell junction found between the interdigitating foot processes of the glomerular epithelium (the podocytes) in the vertebrate kidney, which is adapted for facilitating glomerular filtration.
36061	muscle cell chemotaxis toward tendon cell	P	The directed movement of a muscle cell towards a tendon cell in response to an external stimulus. Tendon cells, for example, produce positive guidance cues that attract muscle cells.
36062	presynaptic periactive zone	C	A region that surrounds the active zone of the presynaptic plasma membrane, and is specialized for the control of synaptic development.
36063	acroblast	C	A cone-shaped structure in the head of a spermatozoon, which is formed by the coalescence of Golgi fragments following the completion of meiosis. The acroblast is situated adjacent to the acrosomal vesicle.
36064	ciliary basal body	C	A membrane-tethered, short cylindrical array of microtubules and associated proteins found at the base of a eukaryotic cilium (also called flagellum) that is similar in structure to a centriole and derives from it. The cilium basal body is the site of assembly and remodelling of the cilium and serves as a nucleation site for axoneme growth. As well as anchoring the cilium, it is thought to provide a selective gateway regulating the entry of ciliary proteins and vesicles by intraflagellar transport.
36065	fucosylation	P	The covalent attachment of a fucosyl group to an acceptor molecule.
36066	protein O-linked fucosylation	P	The process of transferring a fucosyl group to a serine or threonine residues in a protein acceptor molecule, to form an O-linked protein-sugar linkage.
36067	light-dependent chlorophyll biosynthetic process	P	The chemical reactions and pathways resulting in the formation of chlorophyll, any compound of magnesium complexed in a porphyrin (tetrapyrrole) ring and which functions as a photosynthetic pigment, from less complex precursors, which occur in the presence of light.
36068	light-independent chlorophyll biosynthetic process	P	The chemical reactions and pathways resulting in the formation of chlorophyll, any compound of magnesium complexed in a porphyrin (tetrapyrrole) ring and which functions as a photosynthetic pigment, from less complex precursors, which occur in the absence of light.
36069	light-dependent bacteriochlorophyll biosynthetic process	P	The chemical reactions and pathways resulting in the formation of a bacteriochlorophyll, which occur in the presence of light. Bacteriochlorophylls are any of the chlorophylls of photosynthetic bacteria; they differ structurally from the chlorophylls of higher plants.
36070	light-independent bacteriochlorophyll biosynthetic process	P	The chemical reactions and pathways resulting in the formation of a bacteriochlorophyll, which occur in the absence of light. Bacteriochlorophylls are any of the chlorophylls of photosynthetic bacteria; they differ structurally from the chlorophylls of higher plants.
36071	N-glycan fucosylation	P	The process of transferring a fucosyl group to an N-glycan. An N-glycan is the carbohydrate portion of an N-glycoprotein when attached to a nitrogen from asparagine or arginine side-chains.
36072	direct ossification	P	The formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone or a bony substance, that does not require the replacement of preexisting tissues.
36073	perichondral ossification	P	Intramembranous ossification from the surface of a cartilage element as the perichondrium becomes a periosteum, without replacement of cartilage.
36074	metaplastic ossification	P	Direct ossification in which bone formation occurs as result of the direct transformation of non-bone cells into bone cells without cell division.
36075	replacement ossification	P	Ossification that requires the replacement of a preexisting tissue prior to bone tissue formation.
36076	ligamentous ossification	P	Ossification wherein bone tissue forms within ligamentous tissue.
36077	intratendonous ossification	P	Ossification wherein bone tissue forms within tendonous tissue.
36078	minus-end specific microtubule depolymerization	P	The removal of tubulin heterodimers from the minus end of a microtubule.
36079	purine nucleotide-sugar transport	P	The directed movement of a purine nucleotide-sugar into, out of or within a cell. Purine nucleotide-sugars are purine nucleotides in glycosidic linkage with a monosaccharide or monosaccharide derivative.
36080	purine nucleotide-sugar transmembrane transporter activity	F	Enables the transfer of a purine nucleotide-sugar from one side of the membrane to the other. Purine nucleotide-sugars are purine nucleotides in glycosidic linkage with a monosaccharide or monosaccharide derivative.
36081	extracellular ammonia-gated ion channel activity	F	Enables the transmembrane transfer of an ion by a channel that opens when extracellular ammonia (NH3) has been bound by the channel complex or one of its constituent parts.
36082	extracellular phenylacetaldehyde-gated ion channel activity	F	Enables the transmembrane transfer of an ion by a channel that opens when extracellular phenylacetaldehyde has been bound by the channel complex or one of its constituent parts.
36083	positive regulation of unsaturated fatty acid biosynthetic process by positive regulation of transcription from RNA polymerase II promoter	P	Any process that activates or increases the frequency, rate or extent of unsaturated fatty acid biosynthetic process by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter.
36084	GDP-fucose import into endoplasmic reticulum lumen	P	The directed movement of GDP-fucose into the endoplasmic reticulum lumen. GDP-fucose is a substance composed of fucose in glycosidic linkage with guanosine diphosphate.
36085	GDP-fucose import into Golgi lumen	P	The directed movement of GDP-fucose into the Golgi lumen. GDP-fucose is a substance composed of fucose in glycosidic linkage with guanosine diphosphate.
36086	positive regulation of transcription from RNA polymerase II promoter in response to iron ion starvation	P	Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of deprivation of iron ions.
36087	glutathione synthase complex	C	A protein complex composed of two or more polypeptide subunits, and which possesses glutathione synthase activity (catalysis of the reaction: L-gamma-glutamyl-L-cysteine + ATP + glycine = ADP + glutathione + 2 H(+) + phosphate). In eukaryotes, the complex is homodimeric, in E. coli glutathione synthase exists as a tetramer, and in S. pombe the complex exists as a homodimer or a heterotetramer.
36088	D-serine catabolic process	P	The chemical reactions and pathways resulting in the breakdown of D-serine, the D-enantiomer of serine, i.e. (2S)-2-amino-3-hydroxypropanoic acid.
36089	cleavage furrow formation	P	Generation of the cleavage furrow, a shallow groove in the cell surface near the old metaphase plate that marks the site of cytokinesis. This process includes the recruitment and localized activation of signals such as RhoA at the site of the future furrow to ensure that furrowing initiates at the correct site in the cell.
36090	cleavage furrow ingression	P	Advancement of the cleavage furrow from the outside of the cell inward towards the center of the cell. The cleavage furrow acts as a 'purse string' which draws tight to separate daughter cells during cytokinesis and partition the cytoplasm between the two daughter cells. The furrow ingresses until a cytoplasmic bridge is formed.
36091	positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress	P	Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating the organism is under oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
36092	phosphatidylinositol-3-phosphate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of phosphatidylinositol-3-phosphate, a phosphatidylinositol monophosphate carrying the phosphate group at the 3-position.
36093	germ cell proliferation	P	The multiplication or reproduction of germ cells, reproductive cells in multicellular organisms, resulting in the expansion of a cell population.
36094	small molecule binding	F	Interacting selectively and non-covalently with a small molecule, any low molecular weight, monomeric, non-encoded molecule.
36095	positive regulation of invasive growth in response to glucose limitation by positive regulation of transcription from RNA polymerase II promoter	P	Any process that activates or increases the frequency, rate or extent of invasive growth as a result of deprivation of glucose, by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter.
36098	male germ-line stem cell population maintenance	P	The process by which an organism or tissue maintains a population of male germ-line stem cells.
36099	female germ-line stem cell population maintenance	P	The process by which an organism or tissue maintains a population of female germ-line stem cells.
36100	leukotriene catabolic process	P	The chemical reactions and pathways resulting in the breakdown of a leukotriene, a pharmacologically active substance derived from a polyunsaturated fatty acid, such as arachidonic acid.
36101	leukotriene B4 catabolic process	P	The chemical reactions and pathways resulting in the breakdown of leukotriene B4, a leukotriene composed of (6Z,8E,10E,14Z)-eicosatetraenoic acid having (5S)- and (12R)-hydroxy substituents.
36102	leukotriene B4 metabolic process	P	The chemical reactions and pathways involving leukotriene B4, a leukotriene composed of (6Z,8E,10E,14Z)-eicosatetraenoic acid having (5S)- and (12R)-hydroxy substituents.
36103	Kdo2-lipid A metabolic process	P	The chemical reactions and pathways involving Kdo2-lipid A, a lipopolysaccharide (LPS) component.
36104	Kdo2-lipid A biosynthetic process	P	The chemical reactions and pathways resulting in the formation of Kdo2-lipid A, a lipopolysaccharide (LPS) component.
36105	peroxisome membrane class-1 targeting sequence binding	F	Interacting selectively and non-covalently with a class I peroxisomal membrane targeting sequence, any of several sequences of amino acids within a protein that can act as a signal for the localization of the protein into the peroxisome membrane in a PEX19-dependent manner.
36106	peroxisome membrane class-2 targeting sequence binding	F	Interacting selectively and non-covalently with a class II peroxisomal membrane targeting sequence, any of several sequences of amino acids within a protein that can act as a signal for the localization of the protein into the peroxisome membrane in a PEX19-independent manner.
36107	4-amino-4-deoxy-alpha-L-arabinopyranosyl undecaprenyl phosphate metabolic process	P	The chemical reactions and pathways involving 4-amino-4-deoxy-alpha-L-arabinopyranosyl undecaprenyl phosphate, a precursor of 4-amino-4-deoxy-L-arabinose (L-Ara4N).
36108	4-amino-4-deoxy-alpha-L-arabinopyranosyl undecaprenyl phosphate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of 4-amino-4-deoxy-alpha-L-arabinopyranosyl undecaprenyl phosphate, a precursor of 4-amino-4-deoxy-L-arabinose (L-Ara4N).
36109	alpha-linolenic acid metabolic process	P	The chemical reactions and pathways involving alpha-linolenic acid, an unsaturated omega-6 fatty acid that has the molecular formula C18H32O2.
36110	cellular response to inositol starvation	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of inositol.
36111	very long-chain fatty-acyl-CoA metabolic process	P	The chemical reactions and pathways involving very long-chain fatty-acyl-CoAs, any derivative of coenzyme A in which the sulfhydryl group is in a thioester linkage with a medium-chain fatty-acyl group. A very long-chain fatty acid is a fatty acid which has a chain length greater than C22.
36112	medium-chain fatty-acyl-CoA metabolic process	P	The chemical reactions and pathways involving medium-chain fatty-acyl-CoAs, any derivative of coenzyme A in which the sulfhydryl group is in a thioester linkage with a long-chain fatty-acyl group. A medium-chain fatty acid is a fatty acid with a chain length of between C6 and C12.
36113	very long-chain fatty-acyl-CoA catabolic process	P	The chemical reactions and pathways resulting in the breakdown of very long-chain fatty-acyl-CoAs, any derivative of coenzyme A in which the sulfhydryl group is in a thioester linkage with a medium-chain fatty-acyl group. A very long-chain fatty acid is a fatty acid which has a chain length greater than C22.
36114	medium-chain fatty-acyl-CoA catabolic process	P	The chemical reactions and pathways resulting in the breakdown of medium-chain fatty-acyl-CoAs, any derivative of coenzyme A in which the sulfhydryl group is in a thioester linkage with a medium-chain fatty-acyl group. A medium-chain fatty acid is a fatty acid with a chain length of between C6 and C12.
36115	fatty-acyl-CoA catabolic process	P	The chemical reactions and pathways resulting in the breakdown of a fatty-acyl-CoA, any derivative of coenzyme A in which the sulfhydryl group is in thiolester linkage with a fatty-acyl group.
36116	long-chain fatty-acyl-CoA catabolic process	P	The chemical reactions and pathways resulting in the breakdown of long-chain fatty-acyl-CoAs, any derivative of coenzyme A in which the sulfhydryl group is in a thioester linkage with a medium-chain fatty-acyl group. A long-chain fatty acid is a fatty acid with a chain length between C13 and C22.
36117	hyaluranon cable	C	A cable structure, surrounding some cell types (e.g. proximal or bronchial tubular epithelial cells), and composed of hyaluranon (HA), a ubiquitous connective tissue glycosaminoglycan.
36118	hyaluranon cable assembly	P	A process that results in the aggregation, arrangement and bonding together of a hyaluranon cable, a cable structure, surrounding some cell types (e.g. proximal or bronchial tubular epithelial cells), and composed of hyaluranon (HA), a ubiquitous connective tissue glycosaminoglycan.
36119	response to platelet-derived growth factor	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a platelet-derived growth factor stimulus.
36120	cellular response to platelet-derived growth factor stimulus	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a platelet-derived growth factor stimulus.
36121	double-stranded DNA-dependent ATP-dependent DNA helicase activity	F	Catalysis of the reaction: ATP + H2O = ADP + phosphate, in the presence of double-stranded DNA; drives the unwinding of a DNA helix.
36122	BMP binding	F	Interacting selectively and non-covalently with a member of the bone morphogenetic protein (BMP) family.
36123	histone H3-K9 dimethylation	P	The modification of histone H3 by addition of two methyl groups to lysine at position 9 of the histone.
36124	histone H3-K9 trimethylation	P	The modification of histone H3 by addition of three methyl groups to lysine at position 9 of the histone.
36125	fatty acid beta-oxidation multienzyme complex	C	A multienzyme complex possessing three kinds of enzymes that catalyze the chain reactions in the fatty acid beta-oxidation cycle, enoyl-CoA hydratase (ECH), 3-hydroxyacyl-CoA dehydrogenase (HACD), and acetyl-CoA C-acyltransferase (KACT).
36126	sperm flagellum	C	A microtubule-based flagellum (or cilium) that is part of a sperm, a mature male germ cell that develops from a spermatid.
36127	3-sulfino-L-alanine binding	F	Interacting selectively and non-covalently with 3-sulfino-L-alanine (cysteine sulfinate).
36128	CatSper complex	C	A sperm-specific voltage-gated calcium channel that controls the intracellular calcium ion concentration and, thereby, the swimming behavior of sperm. Consists of a heteromeric tetramer surrounding a calcium ion- selective pore. May also contain additional auxiliary subunits.
36129	negative regulation of transcription from RNA polymerase II promoter in response to hydrogen peroxide	P	Any process that decreases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a hydrogen peroxide (H2O2) stimulus.
36130	prostaglandin H2 endoperoxidase reductase activity	F	Catalysis of the reaction: prostaglandin H2 + NADPH + H+ -> prostaglandin F2alpha + NADP+. This reaction is the reduction of prostaglandin H2 ((5Z,13E)-(15S)-9alpha,11alpha-Epidioxy-15-hydroxyprosta-5,13-dienoate) to prostaglandin F2alpha ((5Z,13E)-(15S)-9alpha,11alpha,15-Trihydroxyprosta-5,13-dienoate).
36131	prostaglandin D2 11-ketoreductase activity	F	Catalysis of the reaction: prostaglandin D2 + H+ + NADPH -> 11-epi-prostaglandin F2alpha + NADP+.
36132	13-prostaglandin reductase activity	F	Catalysis of the reaction: 15-keto-prostaglandin + NAD(P)H + H+ -> 13,14-dihydro-15-keto-prostaglandin + NAD(P)+. This reaction is the reduction of 15-keto-prostaglandin.
36133	11-hydroxythromboxane B2 dehydrogenase activity	F	Catalysis of the reaction: thromboxane B2 + NAD+ = 11-dehydro-thromboxane B2 + NADH + H+.
36134	12-hydroxyheptadecatrienoic acid synthase activity	F	Catalysis of the reaction: prostaglandin H2 = 12-hydroxyheptadecatrienoic acid (HHT) + malonaldehyde (MDA).
36135	Schwann cell migration	P	The orderly movement of a Schwann cell from one site to another. A Schwann cell is a glial cell that ensheathes axons of neuron in the peripheral nervous system and is necessary for their maintainance and function.
36136	kynurenine-oxaloacetate transaminase activity	F	Catalysis of the reaction: L-kynurenine + 2-oxoglutarate = 4-(2-aminophenyl)-2,4-dioxobutanoate + L-aspartate.
36137	kynurenine aminotransferase activity	F	Catalysis of the transfer of an amino group from kynurenine to an acceptor, usually a 2-oxo acid.
36138	peptidyl-histidine hydroxylation	P	The hydroxylation of peptidyl-histidine to form peptidyl-hydroxyhistidine.
36139	peptidyl-histidine dioxygenase activity	F	Catalysis of the reaction: peptidyl L-histidine + 2-oxoglutarate + O2 = peptidyl hydroxy-L-histidine + succinate + CO2.
36140	peptidyl-asparagine 3-dioxygenase activity	F	Catalysis of the reaction: peptidyl L-asparagine + 2-oxoglutarate + O2 = peptidyl 3-hydroxy-L-asparagine + succinate + CO2.
36141	L-phenylalanine-oxaloacetate transaminase activity	F	Catalysis of the reaction L-phenylalanine + oxaloacetate = phenylpyruvate + aspartate.
36143	kringle domain binding	F	Interacting selectively and non-covalently with a kringle domain. Kringle domains are protein domains that fold into large loops stabilized by 3 disulfide linkages, and are important in protein-protein interactions with blood coagulation factors.
36145	dendritic cell homeostasis	P	The process of regulating the proliferation and elimination of dendritic cells such that the total number of dendritic cells within a whole or part of an organism is stable over time in the absence of an outside stimulus.
36146	cellular response to mycotoxin	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mycotoxin stimulus. A mycotoxin is a toxic chemical substance produced by fungi.
36147	rumination	P	A digestive process in which food, usually grass or hay, is swallowed into a multi-compartmented stomach, regurgitated, chewed again, and swallowed again.
36148	phosphatidylglycerol acyl-chain remodeling	P	Remodeling the acyl chains of phosphatidylglycerol, through sequential deacylation and re-acylation reactions, to generate phosphatidylglycerol containing different types of fatty acid acyl chains.
36149	phosphatidylinositol acyl-chain remodeling	P	Remodeling the acyl chains of phosphatidylinositol, through sequential deacylation and re-acylation reactions, to generate phosphatidylinositol containing different types of fatty acid acyl chains.
36150	phosphatidylserine acyl-chain remodeling	P	Remodeling the acyl chains of phosphatidylserine, through sequential deacylation and re-acylation reactions, to generate phosphatidylserine containing different types of fatty acid acyl chains.
36151	phosphatidylcholine acyl-chain remodeling	P	Remodeling the acyl chains of phosphatidylcholine, through sequential deacylation and re-acylation reactions, to generate phosphatidylcholine containing different types of fatty acid acyl chains.
36152	phosphatidylethanolamine acyl-chain remodeling	P	Remodeling the acyl chains of phosphatidylethanolamine, through sequential deacylation and re-acylation reactions, to generate phosphatidylethanolamine containing different types of fatty acid acyl chains.
36153	triglyceride acyl-chain remodeling	P	Remodeling the acyl chains of triacylglycerol, through sequential deacylation and re-acylation reactions, to generate triacylglycerol containing different types of fatty acid acyl chains.
36154	diacylglycerol acyl-chain remodeling	P	Remodeling the acyl chains of diacylglycerol, through sequential deacylation and re-acylation reactions, to generate diacylglycerol containing different types of fatty acid acyl chains.
36155	acylglycerol acyl-chain remodeling	P	Remodeling the acyl chains of an acylglycerol, through sequential deacylation and re-acylation reactions, to generate an acylglycerol containing different types of fatty acid acyl chains.
36156	inner dynein arm	C	Inner arm structure present on the outer doublet microtubules of ciliary and flagellar axonemes. The structure of inner dynein arms is complex and may vary within the axoneme. Inner dynein arms are heteromeric, comprising 8 different heavy chains and various subunits. Inner and outer dynein arms have different functions in the generation of microtubule-based motility.
36157	outer dynein arm	C	Outer arm structure present on the outer doublet microtubules of ciliary and flagellar axonemes. Outer dynein arms contain 2-3 heavy chains, two or more intermediate chains and a cluster of 4-8 light chains. Inner and outer dynein arms have different functions in the generation of microtubule-based motility.
36158	outer dynein arm assembly	P	The aggregation, arrangement and bonding together of a set of components to form an axonemal dynein outer arm, an outer arm structure present on the outer doublet microtubules of ciliary and flagellar axonemes.
36159	inner dynein arm assembly	P	The aggregation, arrangement and bonding together of a set of components to form an axonemal dynein inner arm, an inner arm structure present on the outer doublet microtubules of ciliary and flagellar axonemes.
36160	melanocyte-stimulating hormone secretion	P	The regulated release of a melanocyte-stimulating hormone, any of a group of peptide hormones that are produced by cells in the intermediate lobe of the pituitary gland, and stimulate the production of melanin to increase pigmentation.
36161	calcitonin secretion	P	The regulated release of calcitonin, a peptide hormone that participates in calcium and phosphorus metabolism, from a cell.
36162	oxytocin secretion	P	The regulated release of oxytocin, a cyclic nonapeptide hormone with amino acid sequence CYIQNCPLG that also acts as a neurotransmitter in the brain, from a cell. Oxytocin is the principal uterine-contracting and milk-ejecting hormone of the posterior pituitary, and together with the neuropeptide vasopressin, is believed to influence social cognition and behavior.
36163	3-hexaprenyl-4-hydroxy-5-methoxybenzoic acid decarboxylase activity	F	Catalysis of the reaction: 3-hexaprenyl-4-hydroxy-5-methoxybenzoic acid -> 2-hexaprenyl-6-methoxyphenol + CO2.
36164	cell-abiotic substrate adhesion	P	The attachment of a cell to an underlying abiotic (non-living) substrate via adhesion molecules.
36165	invasive growth in response to heat	P	The growth of colonies in filamentous chains of cells as a result of an increase in temperature.
36166	phenotypic switching	P	A reversible switch of a cell from one cell type or form to another, at a frequency above the expected frequency for somatic mutations. Phenotypic switching involves changes in cell morphology and altered gene expression patterns. For example, Candida albicans switches from white cells to opaque cells for sexual mating. Phenotypic switching also occurs in multicellular organisms; smooth muscle cells (SMCs) exhibit phenotypic transitions to allow rapid adaption to fluctuating environmental cues.
36167	phenotypic switching in response to host	P	A reversible switch of a cell from one phenotype to another that occurs upon infection of a host or host cell. For example, Candida albicans switches from a unicellular form to an invasive multicellular filamentous form upon infection of host tissue. Phenotypic switching begins with changes in cell morphology and altered gene expression patterns and ends when the morphology of a population of cells has reverted back to the default state, accompanied by altered expression patterns.
36168	filamentous growth of a population of unicellular organisms in response to heat	P	The process in which a group of unicellular organisms grow in a threadlike, filamentous shape in response to an increase in temperature.
36169	3-methoxy-4-hydroxy-5-decaprenylbenzoic acid decarboxylase activity	F	Catalysis of the reaction: 3-methoxy-4-hydroxy-5-decaprenylbenzoic acid -> 2-methoxy-6-decaprenylphenol + CO2.
36170	filamentous growth of a population of unicellular organisms in response to starvation	P	The process in which a group of unicellular organisms grow in a threadlike, filamentous shape in response to deprivation of nourishment.
36171	filamentous growth of a population of unicellular organisms in response to chemical stimulus	P	The process in which a group of unicellular organisms grow in a threadlike, filamentous shape in response to a chemical stimulus.
36172	thiamine salvage	P	A process that generates thiamine (vitamin B1) from derivatives of it without de novo synthesis.
36173	thiosulfate binding	F	Interacting selectively and non-covalently with the inorganic anion thiosulfate, a sulfur oxide that has formula O3S2.
36174	butane monooxygenase activity	F	Catalysis of the reaction: butane + O2 + NAD(P)H + H+ = butanol + NAD(P)+ + H2O.
36175	ribonucleoside-diphosphate reductase activity, glutaredoxin disulfide as acceptor	F	Catalysis of the reaction: 2'-deoxyribonucleoside diphosphate + glutaredoxin disulfide + H2O -> ribonucleoside diphosphate + glutaredoxin.
36176	response to neutral pH	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a neutral pH (pH close to 7) stimulus. pH is a measure of the acidity or basicity of an aqueous solution.
36177	filamentous growth of a population of unicellular organisms in response to pH	P	The process in which a group of unicellular organisms grow in a threadlike, filamentous shape in response to a pH stimulus. pH is a measure of the acidity or basicity of an aqueous solution.
36178	filamentous growth of a population of unicellular organisms in response to neutral pH	P	The process in which a group of unicellular organisms grow in a threadlike, filamentous shape in response to a neutral pH (pH close to 7) stimulus.
36179	osteoclast maturation	P	A developmental process, independent of morphogenetic (shape) change, that is required for an osteoclast cell to attain its fully functional state. An osteoclast is a specialized phagocytic cell associated with the absorption and removal of the mineralized matrix of bone tissue, and which typically differentiates from monocytes.
36180	filamentous growth of a population of unicellular organisms in response to biotic stimulus	P	The process in which a group of unicellular organisms grow in a threadlike, filamentous shape in response to a biotic (living) stimulus.
36181	protein localization to linear element	P	A cellular protein localization process in which a protein is transported to, or maintained at, a linear element. A linear element is a proteinaceous scaffold associated with S. pombe chromosomes during meiotic prophase.
36182	asperthecin metabolic process	P	The chemical reactions and pathways involving asperthecin, an anthraquinone pigment obtained from the mould Aspergillus nidulans.
36183	asperthecin catabolic process	P	The chemical reactions and pathways resulting in the breakdown of asperthecin, an anthraquinone pigment obtained from the mould Aspergillus nidulans.
36184	asperthecin biosynthetic process	P	The chemical reactions and pathways resulting in the formation of asperthecin, an anthraquinone pigment obtained from the mould Aspergillus nidulans.
36185	13-lipoxin reductase activity	F	Definition: Catalysis of the reaction: 15-oxolipoxin A4 + NAD(P)H + H+ = 13,14-dihydro-15-oxolipoxin A4 + NAD(P)+.
36186	early phagosome membrane	C	The lipid bilayer surrounding an early phagosome.
36187	cell growth mode switching, budding to filamentous	P	The process in which a cell switches from growing as a round budding cell to growing as a filament (elongated cells attached end-to-end). An example of this is the yeast-hyphal transition of Candida albicans.
36188	abieta-7,13-dien-18-al dehydrogenase activity	F	Catalysis of the reaction: abieta-7,13-diene-18-al + H2O + NAD+ = abieta-7,13-diene-18-oate + NADH + H+.
36189	abieta-7,13-diene hydroxylase activity	F	Catalysis of the reaction: abieta-7,13-diene + NADPH + H+ + O2 = abieta-7,13-dien-18-ol + NADP+ + H2O.
36190	indole-2-monooxygenase activity	F	Catalysis of the reaction: indole + NAD(P)H + H+ + O2 = indolin-2-one + NAD(P)+ + H2O.
36191	indolin-2-one monooxygenase activity	F	Catalysis of the reaction: indolin-2-one + NAD(P)H + H+ + O2 = 3-hydroxyindolin-2-one + NAD(P)+ + H2O.
36192	3-hydroxyindolin-2-one monooxygenase activity	F	Catalysis of the reaction: 3-hydroxyindolin-2-one + NAD(P)H + H+ + O2 = 2-hydroxy-2H-1,4-benzoxazin-3(4H)-one + NAD(P)+ + H2O.
36193	2-hydroxy-1,4-benzoxazin-3-one monooxygenase activity	F	Catalysis of the reaction: 2-hydroxy-2H-1,4-benzoxazin-3(4H)-one + NAD(P)H + H+ + O2 = 2,4-dihydroxy-2H-1,4-benzoxazin-3(4H)-one + NAD(P)+ + H2O.
36194	muscle cell projection	C	A prolongation or process extending from a muscle cell. A muscle cell is a mature contractile cell, commonly known as a myocyte. This cell has as part of its cytoplasm myofibrils organized in various patterns.
36195	muscle cell projection membrane	C	The portion of the plasma membrane surrounding a muscle cell projection.
36196	zymosterol metabolic process	P	The chemical reactions and pathways involving zymosterol, (5alpha-cholesta-8,24-dien-3beta-ol).
36197	zymosterol biosynthetic process	P	The chemical reactions and pathways resulting in the formation of zymosterol, (5alpha-cholesta-8,24-dien-3beta-ol).
36198	dTMP salvage	P	Any process which produces dTMP, deoxyribosylthymine monophosphate (2'-deoxyribosylthymine 5'-phosphate) without de novo synthesis.
36199	cholest-4-en-3-one 26-monooxygenase activity	F	Catalysis of the reaction: cholest-4-en-3-one + NADH + H+ + O2 = 26-hydroxycholest-4-en-3-one + NAD+ + H2O. This reaction involves the hydroxylation of the C26 carbon, followed by oxidation of the alcohol to the carboxylic acid via the aldehyde intermediate.
36200	3-ketosteroid 9-alpha-monooxygenase activity	F	Catalysis of the reaction: androsta-1,4-diene-3,17-dione + NADH + H+ + O2 = 9alpha-hydroxyandrosta-1,4-diene-3,17-dione + NAD+ + H2O.
36201	ent-isokaurene C2-hydroxylase activity	F	Catalysis of the reaction: ent-isokaurene + O2 + NADPH + H+ = ent-2alpha-hydroxyisokaurene + H2O + NADP+.
36202	ent-cassa-12,15-diene 11-hydroxylase activity	F	Catalysis of the reaction: ent-cassa-12,15-diene + O2 + NADPH + H+ = ent-11beta-hydroxycassa-12,15-diene + NADP+ + H2O.
36203	taxoid 14-beta-hydroxylase activity	F	Catalysis of the reaction: 10beta-hydroxytaxa-4(20),11-dien-5alpha-yl acetate + O2 + NADPH + H+ = 10beta,14beta-dihydroxytaxa-4(20),11-dien-5alpha-yl acetate + NADP+ + H2O.
36204	abieta-7,13-dien-18-ol hydroxylase activity	F	Catalysis of the reaction: abieta-7,13-dien-18-ol + NADPH + H+ + O2 = abieta-7,13-dien-18-al + NADP+ + 2 H2O. This is a two step reaction. The first step is: abieta-7,13-dien-18-ol + NADPH + H+ + O2 = abieta-7,13-dien-18,18-diol + + NADP+ + H2O. The second step is a spontaneous reaction: abieta-7,13-dien-18,18-diol = abieta-7,13-dien-18-al + H2O.
36205	histone catabolic process	P	The chemical reactions and pathways resulting in the breakdown of a histone protein by individual cells.
36206	regulation of histone gene expression	P	Any process that modulates the frequency, rate or extent of expression of a histone-encoding gene. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein.
36207	positive regulation of histone gene expression	P	Any process that increases the frequency, rate or extent of expression of a histone-encoding gene. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein.
36208	negative regulation of histone gene expression	P	Any process that decreases the frequency, rate or extent of expression of a histone-encoding gene. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein.
36209	9beta-pimara-7,15-diene oxidase activity	F	Catalysis of the reaction: 9beta-pimara-7,15-diene + 3 O2 + 3 NADPH + 3 H+ = 9beta-pimara-7,15-dien-19-oate + 3 NADP+ + 4 H2O. This is a three-step reaction: (a) 9beta-pimara-7,15-diene + O2 + NADPH + H+ = 9beta-pimara-7,15-dien-19-ol + NADP+ + H2O, (b) 9beta-pimara-7,15-dien-19-ol + O2 + NADPH + H+ = 9neta-pimara-7,15-dien-19-al + NADP+ + 2 H2O, (c) 9beta-pimara-7,15-dien-19-al + O2 + NADPH + H+ = 9beta-pimara-7,15-dien-19-oate + NADP+ + H2O.
36210	protein modification process in other organism	P	The covalent alteration performed by one organism of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co-translational, post-translational modifications) in another organism. Includes the modification of charged tRNAs that are destined to occur in a protein (pre-translation modification).
36211	protein modification process	P	The covalent alteration of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co-translational, post-translational modifications). Includes the modification of charged tRNAs that are destined to occur in a protein (pre-translation modification).
36212	contractile ring maintenance	P	The process in which the contractile ring is maintained, typically in response to an internal or external cue.
36213	contractile ring contraction	P	The process of an actomyosin ring getting smaller in diameter.
36214	contractile ring localization	P	The process in which a contractile ring is assembled and/or maintained in a specific location.
36215	response to stem cell factor	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stem cell factor (SCF) stimulus.
36216	cellular response to stem cell factor stimulus	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stem cell factor (SCF) stimulus.
36217	dGTP diphosphatase activity	F	Catalysis of the reaction: dGTP + H2O = dGMP + diphosphate.
36218	dTTP diphosphatase activity	F	Catalysis of the reaction: dTTP + H2O = dTMP + diphosphate.
36219	GTP diphosphatase activity	F	Catalysis of the reaction: GTP + H2O = GMP + diphosphate.
36220	ITP diphosphatase activity	F	Catalysis of the reaction: ITP + H2O = IMP + diphosphate.
36221	UTP diphosphatase activity	F	Catalysis of the reaction: UTP + H2O = UMP + diphosphate.
36222	XTP diphosphatase activity	F	Catalysis of the reaction: XTP + H2O = xanthosine 5'-phosphate + diphosphate.
36223	cellular response to adenine starvation	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of adenine.
36224	pairing center	C	A special chromosome region located towards one end of a chromosome that contains dispersed copies of short, repetitive DNA sequences and functions as a cis-acting element essential for presynaptic homologous chromosome pairing and chromosome-nuclear envelope attachment.
36225	cellular response to vitamin B1 starvation	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of vitamin B1 (also called thiamin and thiamine).
36227	mitotic G2 cell cycle arrest in response to glucose starvation	P	The process in which the mitotic cell cycle is halted during G2 phase as a result of deprivation of glucose.
36228	protein targeting to nuclear inner membrane	P	The process of targeting a protein to, and inserting it into, the nuclear inner membrane; usually uses signals contained within the protein.
36229	L-glutamine import	P	The directed movement of L-glutamine, the L-enantiomer of glutamine, into a cell or organelle.
36230	granulocyte activation	P	The change in morphology and behavior of a granulocyte resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor.
36231	L-threonine import	P	The directed movement of L-threonine, the L-enantiomer of threonine, into a cell or organelle.
36232	L-tyrosine import	P	The directed movement of L-tyrosine, the L-enantiomer of tyrosine, into a cell or organelle.
36233	glycine import	P	The directed movement of glycine into a cell or organelle.
36234	deglucuronidation	P	The removal of glucuronic acid from a conjugated substrate.
36235	acyl deglucuronidation	P	The removal of glucuronic acid from an acyl-glucuronide.
36236	acyl glucuronidation	P	The modification of an substrate by the conjugation of glucuronic acid to form an acyl-glucuronide (also called an acyl-glucuronoside).
36237	acyl-glucuronidase activity	F	Catalysis of the reaction: an acyl-glucuronoside + H2O = an alcohol + D-glucuronate.
36238	gallate dioxygenase activity	F	Catalysis of the reaction: gallate + O2 = (1E)-4-oxobut-1-ene-1,2,4-tricarboxylate.
36239	taxoid 7beta-hydroxylase activity	F	Catalysis of the reaction: taxusin + O2 + NADPH + H+ = 7beta-hydroxytaxusin + NADP+ + H2O.
36240	septal periplasm	C	The region between the plasma membrane and the cell wall, as found in organisms such as filamentous fungi.
36241	glutamate catabolic process to 4-hydroxybutyrate	P	The chemical reactions and pathways resulting in the breakdown of glutamate into 4-hydroxybutyrate.
36242	glutamate catabolic process to succinate via 2-oxoglutarate-dependent GABA-transaminase activity	P	The chemical reactions and pathways resulting in the breakdown of glutamate into succinate, that includes the conversion of 4-aminobutyrate to succinate semialdehyde by the 2-oxoglutarate-dependent gamma aminobutyrate (GABA) transaminase.
36243	succinate-semialdehyde dehydrogenase (NADP+) activity	F	Catalysis of the reaction: succinate semialdehyde + NADP+ + H2O = succinate + NADPH + 2 H+.
36244	cellular response to neutral pH	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a neutral pH (pH close to 7) stimulus. pH is a measure of the acidity or basicity of an aqueous solution.
36245	cellular response to menadione	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a menadione stimulus. Menadione (also called vitamin K3) is a naphthoquinone having a methyl substituent at the 2-position.
36246	phytochelatin 2 import into vacuole	P	The directed movement of phytochelatin 2 (PC2) into the vacuole. Phytochelatin 2 is a glutathione-related peptide composed of (gamma-Glu-Cys)n-Gly where n=2, and where the Glu and Cys residues are linked through a gamma-carboxylamide bond.
36247	phytochelatin 3 import into vacuole	P	The directed movement of phytochelatin 3 (PC3) into the vacuole. Phytochelatin 3 is a glutathione-related peptide composed of (gamma-Glu-Cys)n-Gly where n=3, and where the Glu and Cys residues are linked through a gamma-carboxylamide bond.
36248	phytochelatin 4 import into vacuole	P	The directed movement of phytochelatin 4 (PC4) into the vacuole. Phytochelatin 4 is a glutathione-related peptide composed of (gamma-Glu-Cys)n-Gly where n=4, and where the Glu and Cys residues are linked through a gamma-carboxylamide bond.
36249	cadmium ion import into vacuole	P	The directed movement of cadmium ions into the vacuole.
36250	peroxisome transport along microtubule	P	The directed movement of a peroxisome along a microtubule, mediated by motor proteins.
36251	positive regulation of transcription from RNA polymerase II promoter in response to salt stress	P	Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating the organism is under salt stress. The stress is usually an increase or decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment.
36252	positive regulation of transcription from RNA polymerase II promoter in response to menadione	P	Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a menadione stimulus. Menadione (also called vitamin K3) is a naphthoquinone having a methyl substituent at the 2-position.
36253	response to amiloride	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amiloride stimulus.
36254	cellular response to amiloride	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amiloride stimulus.
36255	response to methylamine	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methylamine stimulus.
36256	cellular response to methylamine	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methylamine stimulus.
36257	multivesicular body organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a multivesicular body. A multivesicular body is a type of late endosome in which regions of the limiting endosomal membrane invaginate to form internal vesicles; membrane proteins that enter the internal vesicles are sequestered from the cytoplasm.
36258	multivesicular body assembly	P	The aggregation, arrangement and bonding together of a set of components to form a multivesicular body, a type of late endosome in which regions of the limiting endosomal membrane invaginate to form internal vesicles; membrane proteins that enter the internal vesicles are sequestered from the cytoplasm.
36259	aerobic raffinose catabolic process	P	The chemical reactions and pathways resulting in the breakdown of raffinose that occur in the presence of oxygen.
36260	RNA capping	P	The sequence of enzymatic reactions by which a cap structure is added to the 5' end of a nascent RNA polymerase II transcript. All RNA polymerase II transcripts receive a 7-methyl-G cap. Then for (at least) small nuclear RNAs (snRNAs) and small nucleolar RNAs (snoRNAs), the7-methyl-G cap is hypermethylated to become a 2,2,7-trimethylguanosine (TMG) cap.
36261	7-methylguanosine cap hypermethylation	P	Hypermethylation of the 7-(mono)methylguanosine (m(7)G) cap structure at the 2' position of the guanosine residue to convert a mono-methylated cap to a 2,2,7-trimethylguanosine cap structure. This type of cap modification occurs on small nuclear RNAs (snRNAs) and small nucleolar RNAs (snoRNAs) and is dependent on prior guanine-N7 methylation.
36262	granulysin production	P	The appearance of granulysin due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
36263	L-DOPA monooxygenase activity	F	Catalysis of the reaction: L-DOPA + O2 = ? + H2O. This reaction catalyzes the oxygenation of the dopamine precursor L-DOPA, to the corresponding o-quinone.
36264	dopamine monooxygenase activity	F	Catalysis of the reaction: dopamine + O2 = ? + H2O. This reaction catalyzes the oxygenation of dopamine to the corresponding o-quinone.
36265	RNA (guanine-N7)-methylation	P	The addition of a methyl group to the N7 atom in the base portion of a guanine nucleotide residue in an RNA molecule.
36266	Cdc48p-Npl4p-Vms1p AAA ATPase complex	C	A multiprotein ATPase complex involved in the release of polyubiquitinated proteins, including those damaged by oxidative stress, from the outer mitochondria membrane into the cytoplasm where they are presented to the proteasome for proteolysis, a process also referred to as mitochondria-associated degradation (MAD). In budding yeast, this complex includes Cdc48p, Npl4p and Vms1p.
36267	invasive filamentous growth	P	The growth of colonies in filamentous chains of cells into a substrate.
36268	swimming	P	Self-propelled movement of an organism from one location to another through water, often by means of active fin movement.
36269	swimming behavior	P	The response to external or internal stimuli that results in the locomotory process of swimming. Swimming is the self-propelled movement of an organism through the water.
36270	response to diuretic	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diuretic stimulus. A diuretic is an agent that promotes the excretion of urine through its effects on kidney function.
36271	response to methylphenidate	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methylphenidate stimulus.
36272	response to gemcitabine	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gemcitabine stimulus. Gemcitabine is a 2'-deoxycytidine having geminal fluoro substituents in the 2'-position, and is used as a drug in the treatment of various carcinomas.
36273	response to statin	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a statin stimulus. Statins are organooxygen compounds whose structure is related to compactin (mevastatin) and which may be used as an anticholesteremic drug due its EC 1.1.1.34/EC 1.1.1.88 (hydroxymethylglutaryl-CoA reductase) inhibitory properties.
36274	response to lapatinib	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lapatinib stimulus.
36275	response to 5-fluorouracil	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 5-fluorouracil stimulus.
36276	response to antidepressant	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antidepressant stimulus, a mood-stimulating drug.
36277	response to anticonvulsant	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an anticonvulsant stimulus, a drug used to prevent seizures or reduce their severity.
36278	positive regulation of transcription from RNA polymerase II promoter in response to nitrogen starvation	P	Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a deprivation of nitrogen.
36279	positive regulation of protein export from nucleus in response to glucose starvation	P	Any process that activates or increases the frequency, rate or extent of directed movement of proteins from the nucleus into the cytoplasm in response to deprivation of glucose.
36280	cellular response to L-canavanine	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-canavanine stimulus. L-canavanine is L-homoserine substituted at oxygen with a guanidino (carbamimidamido) group.
36281	coflocculation	P	The non-sexual aggregation between single-celled organisms of different species.
36282	coflocculation via protein-carbohydrate interaction	P	The non-sexual aggregation between single-celled organisms of different species mediated by interaction of a protein in one species and a carbohydrate in the other species. For example, coflocculation between S. pombe and E. coli is mediated by mannose residues in the yeast cell wall interacting with lectin protein in E. coli cell projections.
36283	positive regulation of transcription factor import into nucleus in response to oxidative stress	P	Any process that activates or increases the frequency, rate or extent of the movement of a transcription factor from the cytoplasm to the nucleus under conditions of oxidative stress.
36284	tubulobulbar complex	C	Actin-based structures involved in establishing close contact between Sertoli-Sertoli cells or Sertoli-spermatids in the seminiferous tubules of the testes.
36285	SAGA complex assembly	P	The aggregation, arrangement and bonding together of a set of components to form a SAGA complex, a SAGA-type histone acetyltransferase complex that contains Spt8 (in budding yeast) or a homolog thereof.
36286	eisosome filament	C	A filamentous cortical structure formed, in S. pombe, by the eisosome component Pil1.
36287	response to iloperidone	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iloperidone stimulus.
36288	response to ximelagatran	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ximelagatran stimulus.
36289	peptidyl-serine autophosphorylation	P	The phosphorylation by a protein of one or more of its own serine amino acid residues, or a serine residue on an identical protein.
36290	protein trans-autophosphorylation	P	The phosphorylation by a protein of a residue on an identical protein. For example, phosphorylation by the other kinase within a homodimer.
36291	protein cis-autophosphorylation	P	The phosphorylation by a protein of one or more of its own amino acid residues.
36292	DNA rewinding	P	The process in which interchain hydrogen bonds between two single-stranded DNA (ssDNA) are reformed to regenerate double-stranded DNA (dsDNA). ssDNA is often bound and stabilized by proteins such as replication protein A (RPA) to form ssDNA bubbles. The bubbles can be rewound by ATP-dependent motors to reform base pairs between strands and thus dsDNA.
36293	response to decreased oxygen levels	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting a decline in the level of oxygen.
36294	cellular response to decreased oxygen levels	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting a decline in the level of oxygen.
36295	cellular response to increased oxygen levels	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting an increase in the level of oxygen.
36296	response to increased oxygen levels	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting an increase in the level of oxygen.
36297	interstrand cross-link repair	P	Removal of a DNA interstrand crosslink (a covalent attachment of DNA bases on opposite strands of the DNA) and restoration of the DNA. DNA interstrand crosslinks occur when both strands of duplex DNA are covalently tethered together (e.g. by an exogenous or endogenous agent), thus preventing the strand unwinding necessary for essential DNA functions such as transcription and replication.
36298	recombinational interstrand cross-link repair	P	Removal of a DNA interstrand crosslink (a covalent attachment of DNA bases on opposite strands of the DNA) and restoration of the DNA by a mechanism that involves the exchange, reciprocal or nonreciprocal, of genetic material between the broken DNA molecule and a homologous region of DNA.
36299	non-recombinational interstrand cross-link repair	P	Removal of a DNA interstrand crosslink (a covalent attachment of DNA bases on opposite strands of the DNA) and restoration of the DNA by a mechanism that does not involve homologous DNA recombination.
36300	B cell receptor internalization	P	A receptor-mediated endocytosis process that results in the movement of a B cell receptor from the plasma membrane to the inside of the cell.
36301	macrophage colony-stimulating factor production	P	The appearance of macrophage colony-stimulating factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
36302	atrioventricular canal development	P	The progression of the atrioventricular canal over time, from its formation to the mature structure. The atrioventricular canal is the part of the heart connecting the atrium to the cardiac ventricle.
36303	lymph vessel morphogenesis	P	The process in which the anatomical structures of lymph vessels are generated and organized. The lymph vessel is the vasculature carrying lymph.
36304	umbilical cord morphogenesis	P	The process in which the anatomical structures of the umbilical cord are generated and organized. The umbilical cord is an organ or embryonic origin consisting of the 2 umbilical arteries and the one umbilical vein. The umbilical cord connects the cardiovascular system of the fetus to the mother via the placenta.
36305	ameloblast differentiation	P	The process in which a relatively unspecialized cell acquires specialized features of an ameloblast, a cylindrical epithelial cell in the innermost layer of the enamel organ.
36306	embryonic heart tube elongation	P	The developmental growth that results in the increase in length of the embryonic heart tube. The embryonic heart tube is an epithelial tube that will give rise to the mature heart.
36307	23S rRNA (adenine(2030)-N(6))-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + adenine(2030) in 23S rRNA = S-adenosyl-L-homocysteine + rRNA containing N(6)-methyladenine(2030) in 23S rRNA.
36308	16S rRNA (guanine(1516)-N(2))-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + guanosine(1516) in 16S rRNA = N(2)-methylguanosine(1516) in 16S rRNA + S-adenosyl-L-homocysteine.
36309	protein localization to M-band	P	Any process in which a protein is transported to, and/or maintained in, the M band. The M band is the midline of aligned thick filaments in a sarcomere.
36310	annealing helicase activity	F	Catalysis of the ATP-dependent rewinding of single-stranded DNA (ssDNA) to reform base pairs between strands. Often acts on ssDNA bubbles bound by replication protein A (RPA).
36311	chitin disaccharide deacetylase activity	F	Catalysis of the reaction: 2-(acetylamino)-4-O-[2-(acetylamino)-2-deoxy-beta-D-glucopyranosyl]-2-deoxy-beta-D-glucopyranose + H2O = 2-(acetylamino)-4-O-(2-amino-2-deoxy-beta-D-glucopyranosyl)-2-deoxy-beta-D-glucopyranose + acetate.
36312	phosphatidylinositol 3-kinase regulatory subunit binding	F	Interacting selectively and non-covalently with a regulatory subunit of phosphatidylinositol 3-kinase. The regulatory subunit associates with the catalytic subunit to regulate both its activity and subcellular location.
36313	phosphatidylinositol 3-kinase catalytic subunit binding	F	Interacting selectively and non-covalently with the catalytic subunit of a phosphatidylinositol 3-kinase. The catalytic subunit catalyzes the addition of a phosphate group to an inositol lipid at the 3' position of the inositol ring.
36314	response to sterol	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sterol stimulus.
36315	cellular response to sterol	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sterol stimulus.
36316	SREBP-SCAP complex retention in endoplasmic reticulum	P	Any process in which the SREBP-SCAP complex is maintained in the endoplasmic reticulum and prevented from moving elsewhere. The SREBP-SCAP complex is formed by the association of sterol regulatory element binding protein (SREBP) and SREBP-cleavage-activating protein (SCAP). In the absence of sterols, the SREBP-SCAP complex is packaged into COPII vesicles and travels to the Golgi apparatus to be processed. In the presence of sterols, the complex binds ER-resident proteins such as INSIG, which retain the complex in the ER.
36317	tyrosyl-RNA phosphodiesterase activity	F	Catalysis of the hydrolysis of a 5' tyrosyl-RNA phosphodiester bond between a protein and RNA. In picornaviruses, this covalent bond connects VPg, a viral-encoded protein essential for RNA replication, to the 5' end of all nascent picornavirus genomes; it is cleaved from viral RNA prior to its engaging in protein synthesis.
36318	peptide pheromone receptor activity	F	Combining with a peptide pheromone, and transmitting the signal across the membrane to initiate a change in cell activity.
36319	mating-type M-factor pheromone receptor activity	F	Combining with the mating-type peptide pheromone M-factor and transmitting the signal across the membrane to initiate a change in cell activity. M-factor is a nine-membered oligopeptide that consists of tyrosyl, threonyl, prolyl, lysyl, valyl, prolyl, tyrosyl, methionyl and methyl S-farnesylcysteinate residues joined in sequence, and is a peptide pheromone released by Schizosaccharomyces pombe cells of the cellular mating type Minus.
36320	mating-type P-factor pheromone receptor activity	F	Combining with the mating-type peptide pheromone P-factor and transmitting the signal across the membrane to initiate a change in cell activity. P-factor is a polypeptide of 23 residues, with the sequence Thr-Tyr-Ala-Asp-Phe-Leu-Arg-Ala-Tyr-Gln-Ser-Trp-Asn-Thr-Phe-Val-Asn-Pro-Asp-Arg-Pro-Asn-Leu, and is a peptide pheromone released by Schizosaccharomyces pombe cells of the cellular mating type Plus.
36321	ghrelin secretion	P	The regulated release of ghrelin from a cell. Ghrelin is a 28 amino acid hunger-stimulating peptide hormone.
36322	pancreatic polypeptide secretion	P	The regulated release of pancreatic polypeptide (PP) from a cell. Pancreatic polypeptide is a 36 amino acid polypeptide secreted by islets of Langerhans cells in the pancreas.
36323	vascular endothelial growth factor receptor-1 signaling pathway	P	Any series of molecular signals initiated by the binding of an extracellular ligand to a vascular endothelial growth factor receptor-1 (VEGFR-1) located on the surface of the receiving cell, and ending with regulation of a downstream cellular process, e.g. transcription.
36324	vascular endothelial growth factor receptor-2 signaling pathway	P	Any series of molecular signals initiated by the binding of an extracellular ligand to a vascular endothelial growth factor receptor-2 (VEGFR-2) located on the surface of the receiving cell, and ending with regulation of a downstream cellular process, e.g. transcription.
36325	vascular endothelial growth factor receptor-3 signaling pathway	P	Any series of molecular signals initiated by the binding of an extracellular ligand to a vascular endothelial growth factor receptor-3 (VEGFR-3) located on the surface of the receiving cell, and ending with regulation of a downstream cellular process, e.g. transcription.
36326	VEGF-A-activated receptor activity	F	Combining with vascular endothelial growth factor A (VEGF-A) and transmitting the signal across the plasma membrane to initiate a change in cell activity.
36327	VEGF-B-activated receptor activity	F	Combining with vascular endothelial growth factor B (VEGF-B) and transmitting the signal across the plasma membrane to initiate a change in cell activity.
36328	VEGF-C-activated receptor activity	F	Combining with vascular endothelial growth factor C (VEGF-C) and transmitting the signal across the plasma membrane to initiate a change in cell activity.
36329	VEGF-D-activated receptor activity	F	Combining with vascular endothelial growth factor D (VEGF-D) and transmitting the signal across the plasma membrane to initiate a change in cell activity.
36330	VEGF-E-activated receptor activity	F	Combining with vascular endothelial growth factor E (VEGF-E) and transmitting the signal across the plasma membrane to initiate a change in cell activity.
36331	avascular cornea development in camera-type eye	P	The progression of an avascular cornea over time, from its formation to the mature structure. Corneal avascularity (the absence of blood vessels in the cornea) is required for optical clarity and optimal vision. Avascular corneas are present in most animals, except Manatees.
36332	placental growth factor-activated receptor activity	F	Combining with placental growth factor (PlGF) and transmitting the signal across the plasma membrane to initiate a change in cell activity.
36333	hepatocyte homeostasis	P	Any biological process involved in the maintenance of the steady-state number of hepatocytes within a population of cells. Hepatocytes are specialized epithelial cells of the liver that are organized into interconnected plates called lobules.
36334	epidermal stem cell homeostasis	P	Any biological process involved in the maintenance of the steady-state number of epidermal stem cells within a population of cells.
36335	intestinal stem cell homeostasis	P	Any biological process involved in the maintenance of the steady-state number of intestinal stem cells within a population of cells.
36336	dendritic cell migration	P	The movement of a dendritic cell within or between different tissues and organs of the body.
36337	Fas signaling pathway	P	A series of molecular signals initiated by the binding of a ligand to the receptor Fas on the surface of the cell, and ending with regulation of a downstream cellular process, e.g. transcription. Fas is a death domain-containing member of the tumor necrosis factor receptor (TNFR) superfamily.
36338	viral membrane	C	The lipid bilayer of a virion, a complete fully infectious extracellular virus particle.
36339	lymphocyte adhesion to endothelial cell of high endothelial venule	P	The attachment of a lymphocyte to an endothelial cell of a high endothelial venule (HEV) via adhesion molecules. A HEV cell is an endothelial cell that is cuboidal, expresses leukocyte-specific receptors, and allows for passage of lymphocytes into bloodstream.
36340	chitin-based cuticle sclerotization by biomineralization	P	The process of hardening a chitin-based cuticle by mineral incorporation. For example, the cuticle of crustaceans is hardened by the incorporation of calcium carbonate.
36341	chitin-based cuticle sclerotization by protein cross-linking	P	The process of hardening of a chitin-based cuticle by protein cross-linking, and the incorporation of phenolic precursors. This mechanism of cuticle hardening occurs in insects and is usually accompanied by darkening of the cuticle.
36342	post-anal tail morphogenesis	P	The process in which a post-anal tail is generated and organized. A post-anal tail is a muscular region of the body that extends posterior to the anus. The post-anal tail may aid locomotion and balance.
36343	psychomotor behavior	P	The specific behavior of an organism that combines cognitive functions and physical movement. For example, driving a car, throwing a ball, or playing a musical instrument.
36344	platelet morphogenesis	P	Generation and organization of a platelet, a non-nucleated disk-shaped cell formed by extrusion from megakaryocytes, found in the blood of all mammals, and mainly involved in blood coagulation.
36345	platelet maturation	P	A developmental process, independent of morphogenetic (shape) change, that is required for a platelet to attain its fully functional state. A platelet is a non-nucleated disk-shaped cell formed by extrusion from megakaryocytes, found in the blood of all mammals, and mainly involved in blood coagulation.
36346	cellular response to L-cysteine	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-cysteine stimulus. L-cysteine is an optically active form of cysteine having L-configuration.
36347	glutathione import into cell	P	The directed movement of glutathione from outside of a cell into the cytoplasmic compartment. This may occur via transport across the plasma membrane or via endocytosis.
36348	hydantoin racemase activity	F	Catalysis of the reaction: D-5-monosubstituted hydantoin = L-5-monosubstituted hydantoin.
36349	galactose-specific flocculation	P	The non-sexual aggregation of single-celled organisms mediated by the binding of cell wall proteins on one cell to galactose residues on the other.
36350	mannose-specific flocculation	P	The non-sexual aggregation of single-celled organisms mediated by the binding of cell wall proteins on one cell to mannose residues on the other.
36351	histone H2A-K13 ubiquitination	P	The modification of histone H2A by addition of ubiquitin group at lysine 13 (H2A-K13) in metazoans, and at the equivalent residue in other organisms. Monoubiquitin is first attached to H2A-K13 and K63-linked ubiquitin chains are then extended from this monoubiquitin.
36352	histone H2A-K15 ubiquitination	P	The modification of histone H2A by addition of ubiquitin group at lysine 15 (H2A-K15) in metazoans, and at the equivalent residue in other organisms. Monoubiquitin is first attached to H2A-K15 and K63-linked ubiquitin chains are then extended from this monoubiquitin.
36353	histone H2A-K119 monoubiquitination	P	The modification of histone H2A by addition of a single ubiquitin group to lysine-119 (H2A- K119) in metazoans, and at the equivalent residue in other organisms.
36354	2-desacetyl-2-hydroxyethyl bacteriochlorophyllide a dehydrogenase activity	F	Catalysis of the reaction: 2-desacetyl-2-hydroxyethyl bacteriochlorophyllide a = bacteriochlorophyllide a + 2 H+.
36355	2-iminoacetate synthase activity	F	Catalysis of the reaction: L-tyrosine + S-adenosyl-L-methionine + reduced acceptor = 2-iminoacetate + 4-methylphenol + 5'-deoxyadenosine + L-methionine + acceptor + 2 H+.
36356	cyclic 2,3-diphosphoglycerate synthetase activity	F	Catalysis of the reaction: 2,3-diphosphoglycerate (DPG) + ATP = cyclic 2,3-diphosphoglycerate (cDPG) + ADP + phosphate.
36357	2-phosphoglycerate kinase activity	F	Catalysis of the reaction: 2-phosphoglycerate + ATP = 2,3-diphosphoglycerate + ADP.
36358	lipoteichoic acid D-alanylation	P	The formation of a D-alanyl ester of lipoteichoic acid by transfer of D-Ala onto a membrane-associated lipoteichoic acid (LTA).
36359	renal potassium excretion	P	The elimination by an organism of potassium in the urine.
36360	sorocarp stalk morphogenesis	P	The process in which the sorocarp stalk is generated and organized. The sorocarp stalk is a tubular structure that consists of cellulose-covered cells stacked on top of each other and surrounded by an acellular stalk tube composed of cellulose and glycoprotein. An example of this process is found in Dictyostelium discoideum.
36361	racemase activity, acting on amino acids and derivatives	F	Catalysis of the interconversion of the two enantiomers of a chiral amino acid or amino acid derivative.
36362	ascus membrane	C	A double layer of lipid molecules that surrounds an ascus, a capsule containing the sexual spores in some fungi.
36363	transforming growth factor beta activation	P	The release of transforming growth factor beta (TGF-beta) from its latent state. TGF-beta is secreted as part of a large latent complex (LLC) that is targeted to the extracellular matrix. Release of TGFbeta from its latent state is required for TGFbeta to bind to its receptors, and can occur by a variety of mechanisms.
36364	transforming growth factor beta1 activation	P	The release of transforming growth factor beta1 (TGF-beta1) from its latent state.
36365	transforming growth factor beta2 activation	P	The release of transforming growth factor beta 2 (TGF-beta2) from its latent state.
36366	transforming growth factor beta3 activation	P	The release of transforming growth factor beta 3 (TGF-beta3) from its latent state.
36367	light adaption	P	The ability of a photoreceptor to adjust to varying levels of light.
36368	cone photoresponse recovery	P	The processes required for a cone photoreceptor to recover, following light activation, so that it can respond to a subsequent light stimulus. Cone recovery requires the shutoff of active participants in the phototransduction cascade, including the visual pigment and downstream signal transducers.
36369	transcription factor catabolic process	P	The chemical reactions and pathways resulting in the breakdown of a sequence-specific DNA binding transcription factor by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome.
36370	D-alanyl carrier activity	F	Accepts activated D-alanine and subsequently transfers D-alanine onto a teichoic acid acceptor molecule. The carrier protein provides an essential link between the D-alanine-D-alanyl carrier protein ligase and the incorporation of D-alanine into the substrate.
36371	protein localization to T-tubule	P	A process in which a protein is transported to, or maintained in, the T-tubule. The T-tubule is an invagination of the plasma membrane of a muscle cell that extends inward from the cell surface around each myofibril.
36372	opsin transport	P	The directed movement of an opsin (a G-protein coupled receptor of photoreceptor cells) into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter or pore.
36373	L-fucose mutarotase activity	F	Catalysis of the reaction: alpha-L-fucose = beta-L-fucose.
36374	glutathione hydrolase activity	F	Catalysis of the reaction: glutathione + H2O = L-cysteinylglycine + L-glutamate.
36375	Kibra-Ex-Mer complex	C	An apical protein complex that contains the proteins Kibra, Expanded and Merlin (Mer), or orthologs thereof. In humans, the complex contains KIBRA, FDM6 and NF2.
36376	sodium ion export from cell	P	The directed movement of sodium ions out of a cell.
36377	arbuscular mycorrhizal association	P	A form of mutualism between a fungus and the roots of a vascular plant, where hyphae of the fungus penetrate the plant cell wall and invaginate its cell membrane. Once inside, the fungus forms highly branched structures for nutrient exchange with the plant called arbuscules. Aids in the acquisition by the plant of nutrients such as phosphorus from the soil.
36378	calcitriol biosynthetic process from calciol	P	Conversion of vitamin D3 from its largely inactive form (calciol, also called cholecalciferol) into a hormonally active form (calcitriol). Conversion requires 25-hydroxylation of calciol in the liver to form calcidiol, and subsequent 1,alpha-hydroxylation of calcidiol in the kidney to form calcitriol.
36379	myofilament	C	Any of the smallest contractile units of a myofibril (striated muscle fiber).
36380	UDP-N-acetylglucosamine-undecaprenyl-phosphate N-acetylglucosaminephosphotransferase activity	F	Catalysis of the reaction: UDP-N-acetyl-alpha-D-glucosamine + ditrans,octacis-undecaprenyl phosphate = UMP + N-acetyl-alpha-D-glucosaminyldiphospho-ditrans,octacis-undecaprenol.
36381	pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity	F	Catalysis of the reaction: D-ribose 5-phosphate + D-glyceraldehyde 3-phosphate + L-glutamine = pyridoxal 5'-phosphate + L-glutamate + 3 H2O + phosphate. The reaction occurs in two steps: L-glutamine + H2O = L-glutamate + NH3, and subsequently D-ribose 5-phosphate + D-glyceraldehyde 3-phosphate + NH3 = pyridoxal 5'-phosphate + 4 H2O + phosphate.
36382	flavin reductase (NADH) activity	F	Catalysis of the reaction: reduced flavin + NAD+ = flavin + NADH + H+.
36383	3-hydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione monooxygenase activity	F	Catalysis of the reaction: 3-hydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione + FMNH2 + O2 = 3,4-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione + FMN + H2O.
36384	cytidine diphosphatase activity	F	Catalysis of the reaction: CDP + H2O = CMP + phosphate.
36385	nucleoid DNA packaging	P	Any process in which DNA and associated proteins are formed into a compact, orderly structure within a nucleoid.
36386	bacterial nucleoid DNA packaging	P	Compaction of DNA in a bacterial nucleoid into a compact structure. Often achieved by DNA supercoiling.
36387	pre-replicative complex	C	A protein-DNA complex that forms at the origin of replication during the initial step of DNA replication and allows the origin to become competent, or 'licensed', for replication.
36388	pre-replicative complex assembly	P	The aggregation, arrangement and bonding together of a set of components to form the pre-replicative complex, a protein-DNA complex that forms at the origin of replication during the initial step of DNA replication and allows the origin to become competent, or 'licensed', for replication.
36389	bacterial pre-replicative complex	C	A protein-DNA complex that forms at the bacterial oriC during the initial step of DNA replication and allows the origin to become competent, or 'licensed', for replication.
36390	pre-replicative complex assembly involved in bacterial-type DNA replication	P	The aggregation, arrangement and bonding together of a set of components to form the bacterial pre-replicative complex, a protein-DNA complex that forms at the bacterial oriC during the initial step of DNA replication and allows the origin to become competent, or 'licensed', for replication.
36391	medial cortex septin ring	C	A ring-shaped structure that forms at the medial cortex of a symmetrically dividing cell at the onset of cytokinesis; composed of members of the conserved family of filament forming proteins called septins as well as septin-associated proteins.
36392	chemokine (C-C motif) ligand 20 production	P	The appearance of chemokine (C-C motif) ligand 20 (CCL20) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
36393	thiocyanate peroxidase activity	F	Catalysis of the reaction: thiocyanate (SCN-) + hydrogen peroxide (H2O2) = hypothiocyanite (OSCN-) + 2 H2O. Catalyzes the hydrogen peroxide oxidation of thiocyanate.
36394	amylase secretion	P	The controlled release of amylase from a cell.
36395	pancreatic amylase secretion	P	The controlled release of amylase from a cell of the pancreas.
36396	MIS complex	C	An mRNA methyltransferase complex that catalyzes the post-transcriptional methylation of adenosine to form N6-methyladenosine (m6A). In budding yeast, the MIS complex consists of Mum2p, Ime4p and Slz1p. In vertebrates, the complex consists of METTL3, METTL14 and WTAP.
36397	formate dehydrogenase (quinone) activity	F	Catalysis of the reaction: formate + a quinone = CO2 + a quinol.
36398	TCR signalosome	C	A multi-protein complex containing at least the T-cell receptor complex and the LAT (linker for activation of T cells) scaffold protein. Also contains a variety of signaling proteins including co-receptors, kinases, phosphatases and adaptors such as CD8. Connects events on the plasma membrane to distal signaling cascades to ultimately modulate T cell biology.
36399	TCR signalosome assembly	P	The aggregation, arrangement and bonding together of a set of components to form a TCR signalosome.
36400	short neuropeptide F receptor activity	F	Combining with a short neuropeptide F and transmitting the signal within the cell to initiate a change in cell activity. Short neuropeptide F is an arthropod peptide of less than 28 residues (as small as 8-10 residues in some species) with a C-terminal RFamide or LRFamide.
36401	pyrokinin receptor activity	F	Combining with a pyrokinin and transmitting the signal within the cell to induce a change in cell activity. Pyrokinins are a group of insect neuropeptides that share the common C-terminal pentapeptide sequence Phe-X-Pro-Arg-Leu-NH2 (X = S, T, K, A, or G). They play a central role in diverse physiological processes including stimulation of gut motility, production and release of sex pheromones, diapause, and pupariation.
36402	proteasome-activating ATPase activity	F	Catalysis of the reaction: ATP + H2O = ADP + phosphate, which promotes unfolding of protein substrates, and channel opening of the core proteasome.
36403	arachidonate 8(S)-lipoxygenase activity	F	Catalysis of the reaction: arachidonate + O(2) = (5Z,8S,9E,11Z,14Z)-8-hydroperoxyicosa-5,9,11,14-tetraenoate.
36404	conversion of ds siRNA to ss siRNA	P	The process in which double-stranded small interfering RNA (ds siRNA) molecules are converted to single-stranded small interfering RNA (ss siRNA).
36405	anchored component of cell outer membrane	C	The component of the cell outer membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping.
36406	anchored component of periplasmic side of cell outer membrane	C	The component of the cell outer membrane consisting of gene products and protein complexes that are tethered to the periplasmic side of membrane by only a covalently attached anchor, embedded in the periplasmic side of the membrane only.
36407	mycolate outer membrane	C	A mycolic acid-rich cell outer membrane containing a lipid bilayer and long-chain mycolic acids (hydroxylated branched-chain fatty acids) that are covalently linked to the cell wall peptidoglycan via an arabinogalactan network. Found in mycobacteria and related genera (e.g. corynebacteria).
36408	histone acetyltransferase activity (H3-K14 specific)	F	Catalysis of the reaction: acetyl-CoA + histone H3 L-lysine (position 14) = CoA + histone H3 N6-acetyl-L-lysine (position 14).
36409	histone H3-K14 acetyltransferase complex	C	A protein complex that can catalyze the acetylation of lysine at position 14 in histone H3.
36410	Mst2 histone acetyltransferase complex	C	A protein complex that can catalyze the acetylation of lysine at position 14 in histone H3, and contains Mst2 as the catalytic subunit. In fission yeast, contains at least Mst2, Nto1, Ptf2, Ptf1 and Eaf6.
36411	H-NS-Cnu complex	C	A trimeric protein complex containing a H-NS homodimer and a Cnu monomer. In bacteria, this complex negatively regulates transcription of a range of genes.
36412	acetyl-CoA:oxalate CoA-transferase	F	Catalysis of the reaction: acetyl-CoA + oxalate = acetate + oxalyl-CoA.
36413	histone H3-R26 citrullination	P	The hydrolysis of peptidyl-arginine to form peptidyl-citrulline at position 26 in histone H3.
36414	histone citrullination	P	The hydrolysis of peptidyl-arginine to form peptidyl-citrulline on a histone protein.
36415	regulation of tRNA stability	P	Any process that modulates the propensity of transfer RNA (tRNA) molecules to degradation. Includes processes that both stabilize and destabilize tRNAs.
36416	tRNA stabilization	P	Prevention of degradation of tRNA molecules.
36417	tRNA destabilization	P	Any process that decreases the stability of a tRNA molecule, making it more vulnerable to degradative processes.
36418	intrinsic component of mycolate outer membrane	C	The component of the mycolate outer membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.
36419	integral component of mycolate outer membrane	C	The component of the mycolate outer membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
36420	extrinsic component of mycolate outer membrane	C	The component of mycolate outer membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
36421	extrinsic component of external side of mycolate outer membrane	C	The component of mycolate membrane consisting of gene products and protein complexes that are loosely bound to its external surface, but not integrated into the hydrophobic region.
36422	heptaprenyl diphosphate synthase activity	F	Catalysis of the reaction: (2E,6E)-farnesyl diphosphate + 4 isopentenyl diphosphate = 4 diphosphate + all-trans-heptaprenyl diphosphate.
36423	hexaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) activity	F	Catalysis of the reaction: (2E,6E)-farnesyl diphosphate + 3 isopentenyl diphosphate = 3 diphosphate + all-trans-hexaprenyl diphosphate.
36424	L-phosphoserine phosphatase activity	F	Catalysis of the reaction: O-phospho-L-serine + H2O <=> L-serine + phosphate.
36425	D-phosphoserine phosphatase activity	F	Catalysis of the reaction: O-phospho-D-serine + H2O <=> L-serine + phosphate.
36426	ditrans, polycis-undecaprenyl-phosphate mannosyltransferase activity	F	Catalysis of the reaction: ditrans,octacis-undecaprenyl phosphate + GDP-alpha-D-mannose = D-mannosyl undecaprenyl phosphate+ GDP.
36427	all-trans-undecaprenyl-phosphate mannosyltransferase activity	F	Catalysis of the reaction: all-trans-undecaprenyl phosphate + GDP-alpha-D-mannose = D-mannosyl undecaprenyl phosphate + GDP.
36428	adenosylcobinamide kinase (GTP-specific) activity	F	Catalysis of the reaction: adenosylcobinamide + GTP = adenosylcobinamide phosphate + GDP + H+.
36429	adenosylcobinamide kinase (ATP-specific) activity	F	Catalysis of the reaction: adenosylcobinamide + ATP = adenosylcobinamide phosphate + ADP + H+.
36430	CMP kinase activity	F	Catalysis of the reaction: ATP + CMP = ADP + CDP.
36431	dCMP kinase activity	F	Catalysis of the reaction: ATP + dCMP = ADP + dCDP.
36432	all-trans undecaprenol kinase activity	F	Catalysis of the reaction: ATP + undecaprenol + all-trans-undecaprenyl phosphate + ADP + H+.
36433	di-trans, poly-cis-undecaprenol kinase activity	F	Catalysis of the reaction: di-trans, octa-cis-undecaprenol + ATP = di-trans,octa-cis-undecaprenyl phosphate + ADP + H+.
36434	nitronate monooxygenase (FMN-linked) activity	F	Catalysis of the reaction: ethylnitronate + FMNH(2) + O(2) = acetaldehyde + FMN + H(2)O + H(+) + nitrite.
36435	K48-linked polyubiquitin binding	F	Interacting selectively and non-covalently and non-covalently with a polymer of ubiquitin formed by linkages between lysine residues at position 48 of the ubiquitin monomers.
36436	Isw1a complex	C	An Isw1 complex that binds DNA and has nucleosome-stimulated ATPase activity. In S. cerevisiae, contains an Isw1p ATPase subunit in complex with Ioc3p.
36437	Isw1b complex	C	An Isw1 complex that binds DNA and has nucleosome-stimulated ATPase activity. In S. cerevisiae, contains an Isw1p ATPase subunit in complex with Ioc2p and Ioc4p.
36438	maintenance of lens transparency	P	A homeostatic process in which the lens is maintained in a highly refractive, transparent state to allow for optimal focusing of light on the retina.
36439	glycerol-3-phosphate dehydrogenase [NADP+] activity	F	Catalysis of the reaction: glycerol 3-phosphate + NADP+ = glycerone phosphate + H+ + NADPH.
36440	citrate synthase activity	F	Catalysis of the reaction: acetyl-CoA + H2O + oxaloacetate = citrate + CoA.
36441	2-dehydropantolactone reductase activity	F	Catalysis of the reaction: (R)-pantolactone + NADP+ = 2-dehydropantolactone + NADPH + H+.
36442	hydrogen-exporting ATPase activity	F	Catalysis of the transfer of protons from one side of a membrane to the other according to the reaction: ATP + H2O + H+(in) -> ADP + phosphate + H+(out).
36443	dermatan 6-sulfotransferase activity	F	Catalysis of the reaction: 3'-phosphoadenylyl sulfate + dermatan = adenosine 3',5'-bisphosphate + dermatan 6'-sulfate.
36444	mitochondrial calcium uptake	P	A process in which a calcium ion (Ca2+) is transported from one side of a membrane to the other into the mitochondrion by means of some agent such as a transporter or pore.
36445	neuronal stem cell division	P	The self-renewing division of a neuronal stem cell.
36446	myofibroblast differentiation	P	The process in which an undifferentiated cell acquires the features of a myofibroblast cell.
36447	cellular response to sugar-phosphate stress	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the accumulation of sugar-phosphate.
36448	cellular response to glucose-phosphate stress	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the accumulation of glucose-phosphate.
36449	microtubule minus-end	C	The end of a microtubule that does not preferentially grow (polymerize).
36450	polyuridylation-dependent decapping of nuclear-transcribed mRNA	P	Cleavage of the 5'-cap of a nuclear-transcribed mRNA that has been modified by the enzymatic addition of a sequence of uridylyl residues (polyuridylation) at the 3' end.
36451	cap mRNA methylation	P	Methylation of the 2'-O-ribose of the first or second transcribed nucleotide of a 5'-capped mRNA.
36452	ESCRT complex	C	An endosomal sorting complex required for transport.
36453	transitive RNA interference	P	An RNA interference where the silencing signal spreads along the target mRNA in a 5' or 3' direction, outside of the initial target sequence.
36454	growth factor complex	C	A protein complex that has growth factor activity.
36455	iron-sulfur transferase activity	F	Catalysis of the transfer of a iron-sulfur cluster from one compound (donor) to another (acceptor).
36456	L-methionine-(S)-S-oxide reductase activity	F	Catalysis of the reaction: L-methionine (S)-S-oxide + thioredoxin -> L-methionine + thioredoxin disulfide + H2O.
36457	keratohyalin granule	C	A cytoplasmic, non-membrane bound granule of, at least, keratinocyte. Associated to keratin intermediate filaments and partially crosslinked to the cell envelope.
36458	hepatocyte growth factor binding	F	Interacting selectively and non-covalently with a hepatocyte growth factor.
36459	thiol-dependent ubiquitinyl hydrolase activity	F	Catalysis of the thiol-dependent hydrolysis of an ester, thioester, amide, peptide or isopeptide bond formed by the C-terminal glycine of ubiquitin.
36460	cellular response to cell envelope stress	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stress acting at the cell envelope.
36461	BLOC-2 complex binding	F	Interacting selectively and non-covalently with a BLOC-2 complex, a protein complex required for the biogenesis of specialized organelles of the endosomal-lysosomal system, such as melanosomes and platelet dense granules.
36462	TRAIL-activated apoptotic signaling pathway	P	An extrinsic apoptotic signaling pathway initiated by the binding of the ligand TRAIL (tumor necrosis factor-related apoptosis-inducing ligand) to a death receptor on the cell surface.
36463	TRAIL receptor activity	F	Combining with the ligand TRAIL (tumor necrosis factor-related apoptosis-inducing ligand) and transmitting the signal from one side of the plasma membrane to the other to initiate apoptotic cell death.
36464	cytoplasmic ribonucleoprotein granule	C	A ribonucleoprotein granule located in the cytoplasm.
36465	synaptic vesicle recycling	P	The trafficking of synaptic vesicles from the pre-synaptic membrane so the vesicle can dock and prime for another round of exocytosis and neurotransmitter release. Recycling occurs after synaptic vesicle exocytosis, and is necessary to replenish presynaptic vesicle pools, sustain transmitter release and preserve the structural integrity of the presynaptic membrane. Recycling can occur following transient fusion with the presynaptic membrane (kiss and run), or via endocytosis of presynaptic membrane.
36466	synaptic vesicle recycling via endosome	P	Synaptic vesicle recycling where vesicles endocytose via clathrin-coated pits, re-acidify, and refill with neurotransmitters after passing through an endosomal intermediate.
36467	5-hydroxy-L-tryptophan decarboxylase activity	F	Catalysis of the reaction: 5-hydroxy-L-tryptophan + H+ = CO2 + serotonin.
36468	L-dopa decarboxylase activity	F	Catalysis of the reaction: L-dopa + H+ = CO2 + dopamine.
36469	L-tryptophan decarboxylase activity	F	Catalysis of the reaction: L-tryptophan + H+ = CO2 + tryptamine.
36470	tyrosine 3-monooxygenase activator activity	F	Interacts with and increases tyrosine 3-monooxygenase (tyrosine hydroxylase) activity.
36471	cellular response to glyoxal	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glyoxal stimulus.
36472	suppression by virus of host protein-protein interaction	P	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of interaction between host proteins.
36473	cell death in response to oxidative stress	P	Any biological process that results in permanent cessation of all vital functions of a cell upon exposure to an oxidative stress stimulus.
36474	cell death in response to hydrogen peroxide	P	Any biological process that results in permanent cessation of all vital functions of a cell upon exposure to hydrogen peroxide (H2O2).
36475	neuron death in response to oxidative stress	P	Any biological process that results in permanent cessation of all vital functions of a neuron upon exposure to an oxidative stress stimulus.
36476	neuron death in response to hydrogen peroxide	P	Any biological process that results in permanent cessation of all vital functions of a neuron upon exposure to hydrogen peroxide (H2O2).
36477	somatodendritic compartment	C	The region of a neuron that includes the cell body (cell soma) and the dendrite, but excludes the axon.
36478	L-dopa decarboxylase activator activity	F	Interacts with and increases L-dopa decarboxylase activity.
36479	peroxidase inhibitor activity	F	Interacts with, and stops, prevents or reduces the activity of a peroxidase.
36480	neuron intrinsic apoptotic signaling pathway in response to oxidative stress	P	A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a neuron. The pathway is induced in response to oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, and ends when the execution phase of apoptosis is triggered.
36481	intrinsic apoptotic signaling pathway in response to hydrogen peroxide	P	A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced in response to hydrogen peroxide (H2O2).
36482	neuron intrinsic apoptotic signaling pathway in response to hydrogen peroxide	P	A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a neuron in response to hydrogen peroxide.
36483	neuron intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress	P	A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a neuron. The pathway is induced in response to a stimulus indicating endoplasmic reticulum (ER) stress, and ends when the execution phase of apoptosis is triggered. ER stress usually results from the accumulation of unfolded or misfolded proteins in the ER lumen.
36484	trunk neural crest cell migration	P	The characteristic movement of trunk neural crest cells from the neural tube to other locations in the vertebrate embryo.
36485	dorsolateral trunk neural crest cell migration	P	The movement of trunk neural crest cells from the neural tube, travelling dorso-laterally into the ectoderm and continuing toward the ventral midline of the belly. These migrating trunk neural crest cells become melanocytes, the melanin-forming pigment cells.
36486	ventral trunk neural crest cell migration	P	The movement of trunk neural crest cells from the neural tube, travelling ventrally through the anterior half of each sclerotome. Trunk neural crest cells that remain in the sclerotome form the dorsal root ganglia containing the sensory neurons. Trunk neural crest cells that continue more ventrally form the sympathetic ganglia, the adrenal medulla, and the nerve clusters surrounding the aorta.
36487	nitric-oxide synthase inhibitor activity	F	Interacts with, and stops, prevents or reduces the activity of nitric oxide synthase.
36488	CHOP-C/EBP complex	C	A heterodimeric protein complex that is composed of the transcription factor CHOP (GADD153) and a member of the C/EBP family of transcription factors.
36489	neuromelanin biosynthetic process	P	The chemical reactions and pathways resulting in the formation of neuromelanin. Neuromelanin is a polymer of 5,6-dihydroxyindole monomers.
36490	regulation of translation in response to endoplasmic reticulum stress	P	Modulation of the frequency, rate or extent of translation as a result of endoplasmic reticulum stress.
36491	regulation of translation initiation in response to endoplasmic reticulum stress	P	Any process that modulates the frequency, rate or extent of translation initiation, as a result of endoplasmic reticulum stress.
36492	eiF2alpha phosphorylation in response to endoplasmic reticulum stress	P	The addition of a phosphate group on to the translation initiation factor eIF2alpha, as a result of endoplasmic reticulum stress.
36493	positive regulation of translation in response to endoplasmic reticulum stress	P	Any process that activates, or increases the frequency, rate or extent of translation as a result of endoplasmic reticulum stress.
36494	positive regulation of translation initiation in response to endoplasmic reticulum stress	P	Any process that activates, or increases the frequency, rate or extent of translation initiation as a result of endoplasmic reticulum stress.
36495	negative regulation of translation initiation in response to endoplasmic reticulum stress	P	Any process that stops, prevents, or reduces the frequency, rate or extent of translation initiation as a result of endoplasmic reticulum stress.
36496	regulation of translational initiation by eIF2 alpha dephosphorylation	P	Any process that modulates the frequency, rate or extent of translation initiation in response to stress by the dephosphorylation of eIF2 alpha.
36497	eIF2alpha dephosphorylation in response to endoplasmic reticulum stress	P	The removal of a phosphate group from the translation initiation factor eIF2alpha, as a result of endoplasmic reticulum stress.
36498	IRE1-mediated unfolded protein response	P	A series of molecular signals mediated by the endoplasmic reticulum stress sensor IRE1 (Inositol-requiring transmembrane kinase/endonuclease). Begins with activation of IRE1 in response to endoplasmic reticulum (ER) stress, and ends with regulation of a downstream cellular process, e.g. transcription. One target of activated IRE1 is the transcription factor HAC1 in yeast, or XBP1 in mammals; IRE1 cleaves an intron of a mRNA coding for HAC1/XBP1 to generate an activated HAC1/XBP1 transcription factor, which controls the up regulation of UPR-related genes. At least in mammals, IRE1 can also signal through additional intracellular pathways including JNK and NF-kappaB.
36499	PERK-mediated unfolded protein response	P	A series of molecular signals mediated by the endoplasmic reticulum membrane stress sensor PERK (PKR-like ER kinase). Begins with activation of PERK in response to endoplasmic reticulum (ER) stress and ends with regulation of a downstream cellular process, e.g. transcription. The main substrate of PERK is the translation initiation factor eIF2alpha. Serine-phosphorylation of eIF2alpha by PERK inactivates eIF2alpha and inhibits general protein translation. In addition, eIF2alpha phosphorylation preferentially increases the translation of selective mRNAs such as ATF4 (activating transcription factor 4), which up regulates a subset of UPR genes required to restore folding capacity.
36500	ATF6-mediated unfolded protein response	P	A series of molecular signals mediated by the endoplasmic reticulum membrane stress sensor ATF6 (activating transcription factor 6). Begins with activation of ATF6 in response to endoplasmic reticulum (ER) stress, and ends with regulation of a downstream cellular process, e.g. transcription. Under conditions of endoplasmic reticulum stress, ATF6 translocates to the Golgi where it is processed by proteases to release a cytoplasmic domain (ATF6f), which operates as a transcriptional activator of many genes required to restore folding capacity.
36501	UFD1-NPL4 complex	C	A dimeric protein complex that contains the co-factors for the ATPase VCP/p97 (Cdc48p in budding yeast). In mammals, this complex consists of UFD1L (UFD1) and NPLOC4 (NPL4). In budding yeast, the complex is a dimer of Ufd1p and Npl4p.
36502	Derlin-1-VIMP complex	C	A protein complex containing, in mammals, Derlin-1 and VCP-interacting membrane protein (VIMP). The complex links the p97/VCP-containing ATPase complex with Derlin-1 during translocation of protein substrates from the endoplasmic reticulum to the cytosol for degradation by the cytosolic proteasome.
36503	ERAD pathway	P	The series of steps necessary to target endoplasmic reticulum (ER)-resident proteins for degradation by the cytoplasmic proteasome. Begins with recognition of the ER-resident protein, includes retrotranslocation (dislocation) of the protein from the ER to the cytosol, protein modifications necessary for correct substrate transfer (e.g. ubiquitination), transport of the protein to the proteasome, and ends with degradation of the protein by the cytoplasmic proteasome.
36504	Golgi membrane fusion	P	The joining of two lipid bilayers that surround the Golgi apparatus to form a single Golgi membrane.
36505	prosaposin receptor activity	F	Combining with prosaposin to initiate a change in cell activity. Prosaposin is the glycoprotein precursor of four cleavage products (saposins A, B, C and D).
36506	maintenance of unfolded protein	P	Maintaining a protein in an unfolded, soluble state.
36507	protein demannosylation	P	The removal of one or more mannose residues from a mannosylated protein.
36508	protein alpha-1,2-demannosylation	P	The removal of one or more alpha 1,2-linked mannose residues from a mannosylated protein.
36509	trimming of terminal mannose on B branch	P	The removal of an alpha-1,2-linked mannose from the B-chain of a glycoprotein oligosaccharide in the endoplasmic reticulum.
36510	trimming of terminal mannose on C branch	P	The removal of an alpha-1,2-linked mannose from the C-chain of a glycoprotein oligosaccharide in the endoplasmic reticulum.
36511	trimming of first mannose on A branch	P	The removal of the first alpha-1,2-linked mannose from the A-chain of a glycoprotein oligosaccharide in the endoplasmic reticulum.
36512	trimming of second mannose on A branch	P	The removal of the second alpha-1,2-linked mannose from the A-chain of a glycoprotein oligosaccharide in the endoplasmic reticulum.
36513	Derlin-1 retrotranslocation complex	C	A protein complex that functions in the retrotranslocation step of ERAD (ER-associated protein degradation), and includes at its core Derlin-1 oligomers forming a retrotranslocation channel.
36514	dopaminergic neuron axon guidance	P	The chemotaxis process that directs the migration of an axon growth cone of a dopaminergic neuron to a specific target site in response to a combination of attractive and repulsive cues.
36515	serotonergic neuron axon guidance	P	The chemotaxis process that directs the migration of an axon growth cone of a serotonergic neuron to a specific target site in response to a combination of attractive and repulsive cues.
36516	chemoattraction of dopaminergic neuron axon	P	The process in which a dopaminergic neuron growth cone is directed to a specific target site in response to an attractive chemical signal.
36517	chemoattraction of serotonergic neuron axon	P	The process in which a serotonergic neuron growth cone is directed to a specific target site in response to an attractive chemical signal.
36518	chemorepulsion of dopaminergic neuron axon	P	The process in which a dopaminergic neuron growth cone is directed to a specific target site in response to a repulsive chemical cue.
36519	chemorepulsion of serotonergic neuron axon	P	The process in which a serotonergic neuron growth cone is directed to a specific target site in response to a repulsive chemical cue.
36520	astrocyte-dopaminergic neuron signaling	P	Cell-cell signaling that mediates the transfer of information from an astrocyte to a dopaminergic neuron.
36521	modulation by symbiont of host protein localization to phagocytic vesicle	P	Any process in which an organism modulates the frequency, rate or extent of protein localisation to the host phagosome. The host is defined as the larger of the organisms involved in a symbiotic interaction.
36522	negative regulation by symbiont of host protein localization to phagocytic vesicle	P	Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of protein localisation to the host phagosome. The host is defined as the larger of the organisms involved in a symbiotic interaction.
36523	positive regulation by symbiont of host cytokine secretion	P	Any process in which an organism activates, maintains or increases the frequency, rate or extent of cytokine secretion in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
36524	protein deglycase activity	F	Catalysis of the removal of a sugar or dicarbonyl from a lysine residue of a glycated protein.
36525	protein deglycation	P	The removal of a sugar or dicarbonyl from a glycated protein.
36526	peptidyl-cysteine deglycation	P	The removal of a sugar or dicarbonyl from a cysteine residue of a glycated protein.
36527	peptidyl-arginine deglycation	P	The removal of a sugar or dicarbonyl from an arginine residue of a glycated protein.
36528	peptidyl-lysine deglycation	P	The removal of a sugar or dicarbonyl from a lysine residue of a glycated protein.
36529	protein deglycation, glyoxal removal	P	The removal of glyoxal from a glycated protein, to form glycolate and a deglycated protein.
36530	protein deglycation, methylglyoxal removal	P	The removal of methylglyoxal from a glycated protein, to form lactate and a deglycated protein.
36531	glutathione deglycation	P	The removal of a sugar or dicarbonyl from glycated glutathione. Glutathione is the tripeptide glutamylcysteinylglycine.
38001	paracrine signaling	P	The transfer of information from one cell to another, where the signal travels from the signal-producing cell to the receiving cell by passive diffusion or bulk flow in intercellular fluid. The signaling cell and the receiving cell are usually in the vicinity of each other.
38002	endocrine signaling	P	The transfer of information from one cell to another, where an endocrine hormone is transported from the signal-producing cell to the receiving cell via the circulatory system (via blood, lymph or cerebrospinal fluid). The signaling cell and the receiving cell are often distant to each other.
38003	opioid receptor signaling pathway	P	The series of molecular signals generated as a consequence of an opioid receptor binding to one of its physiological ligands.
38004	epidermal growth factor receptor ligand maturation	P	Any process leading to the attainment of the full functional capacity of a ligand for an epidermal growth factor receptor. The ligand is functional when it can bind to and activate an epidermal growth factor receptor.
38005	peptide bond cleavage involved in epidermal growth factor receptor ligand maturation	P	The hydrolysis of a peptide bond or bonds within a ligand for the epidermal growth factor receptor, as part of protein maturation, the process leading to the attainment of the full functional capacity of a protein. In Drosophila for example, in the Golgi apparatus of the signal producing cell, Spitz is cleaved within its transmembrane domain to release a functional soluble extracellular fragment.
38006	netrin receptor activity involved in chemoattraction	F	Combining with a netrin signal and transmitting the signal from one side of the membrane to the other to contribute to the directed movement of a motile cell towards a higher concentration of netrin.
38007	netrin-activated signaling pathway	P	A series of molecular events initiated by the binding of a netrin protein to a receptor on the surface of the target cell, and ending with regulation of a downstream cellular process, e.g. transcription. Netrins can act as chemoattractant signals for some cells and chemorepellent signals for others. Netrins also have roles outside of cell and axon guidance.
38008	TRAF-mediated signal transduction	P	The intracellular process in which a signal is passed on to downstream components within the cell via a tumor necrosis factor receptor-associated factor (TRAF). TRAFs are directly or indirectly recruited to the intracellular domains of cell surface receptors, and engage other signaling proteins to transfer the signal from a cell surface receptor to other intracellular signaling components.
38009	regulation of signal transduction by receptor internalization	P	Any process that modulates the frequency, rate or extent of signal transduction by the movement of a signaling receptor from the plasma membrane to the inside of the cell. Receptor internalization can have a positive or negative effect on a signaling pathway.
38010	positive regulation of signal transduction by receptor internalization	P	Any process in which the internalization of a signaling receptor activates or increases the frequency, rate or extent of signal transduction. Receptor internalization can enhance signaling by concentrating signaling molecules in one location, or by moving a ligand-activated receptor to the location of downstream signaling proteins. Endosomes for example can serve as important intracellular signaling platforms.
38011	negative regulation of signal transduction by receptor internalization	P	Any process in which internalization of a signaling receptor stops, prevents, or reduces the frequency, rate or extent of signal transduction. Receptor internalization can attenuate or reduce the strength of signaling by reducing the concentration of cell surface receptors available to ligands.
38012	negative regulation of Wnt signaling pathway by Wnt receptor internalization	P	Any process in which internalization of a Wnt receptor stops, prevents, or reduces the frequency, rate or extent of Wnt signal transduction.
38013	positive regulation of Wnt signaling pathway by Wnt receptor internalization	P	Any process in which internalization of a Wnt receptor activates or increases the frequency, rate or extent of the Wnt signaling pathway.
38014	negative regulation of insulin receptor signaling pathway by insulin receptor internalization	P	Any process in which internalization of an insulin receptor stops, prevents, or reduces the frequency, rate or extent of insulin receptor signal transduction. Internalization of insulin in association with its receptor clears insulin from the circulation and is necessary for subsequent insulin dissociation from the receptor and insulin degradation.
38015	positive regulation of insulin receptor signaling pathway by insulin receptor internalization	P	Any process in which internalization of an insulin receptor activates or increases the frequency, rate or extent of the insulin receptor signaling pathway. Endocytosis of activated receptors can concentrate receptors within endosomes and allow the insulin receptor to phosphorylate substrates that are spatially distinct from those accessible at the plasma membrane.
38016	insulin receptor internalization	P	A receptor-mediated endocytosis process that results in the movement of an insulin receptor from the plasma membrane to the inside of the cell.
38017	Wnt receptor internalization	P	A receptor-mediated endocytosis process that results in the movement of a Wnt receptor from the plasma membrane to the inside of the cell.
38018	Wnt receptor catabolic process	P	The chemical reactions and pathways resulting in the breakdown of a Wnt receptor. Internalized Wnt receptors can be recycled to the plasma membrane or sorted to lysosomes for protein degradation.
38019	Wnt receptor recycling	P	The process that results in the return of a Wnt receptor to an active state at the plasma membrane. An active state is when the receptor is ready to receive a Wnt signal. Internalized Wnt receptors can be recycled to the plasma membrane or sorted to lysosomes for protein degradation.
38020	insulin receptor recycling	P	The process that results in the return of an insulin receptor to an active state at the plasma membrane. An active state is when the receptor is ready to receive an insulin signal. Internalized insulin receptors can be recycled to the plasma membrane or sorted to lysosomes for protein degradation.
38021	leptin receptor activity	F	Combining with the fat-cell specific hormone leptin and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
38022	G-protein coupled olfactory receptor activity	F	Combining with an odorant and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.
38023	signaling receptor activity	F	Receiving a signal and transmitting the signal in the cell to initiate a change in cell activity. A signal is a physical entity or change in state that is used to transfer information in order to trigger a response.
38024	cargo receptor activity	F	Combining selectively with an extracellular substance and delivering the substance into the cell via endocytosis.
38025	reelin receptor activity	F	Combining with the secreted glycoprotein reelin, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
38026	reelin-mediated signaling pathway	P	A series of molecular signals initiated by the binding of reelin (a secreted glycoprotein) to a receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.
38027	apolipoprotein A-I-mediated signaling pathway	P	A series of molecular signals initiated by the binding of apolipoprotein A-I to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.
38028	insulin receptor signaling pathway via phosphatidylinositol 3-kinase	P	The series of molecular signals generated as a consequence of the insulin receptor binding to its physiological ligand, where the signal is passed on via the phosphatidylinositol 3-kinase cascade.
38029	epidermal growth factor receptor signaling pathway via MAPK cascade	P	The series of molecular signals generated as a consequence of an epidermal growth factor receptor binding to one of its physiological ligands, where the signal is passed on via the MAPKKK cascade.
38030	non-canonical Wnt signaling pathway via MAPK cascade	P	The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, where the signal is passed on via the MAPKKK cascade.
38031	non-canonical Wnt signaling pathway via JNK cascade	P	The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, where the signal is passed on via the JNK cascade.
38032	termination of G-protein coupled receptor signaling pathway	P	The signaling process in which G-protein coupled receptor signaling is brought to an end. For example, through the action of GTPase-activating proteins (GAPs) that act to accelerate hydrolysis of GTP to GDP on G-alpha proteins, thereby terminating the transduced signal.
38033	positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway	P	A series of molecular signals initiated by the binding of a vascular endothelial growth factor (VEGF) to a VEGFR on the surface of a cell, which activates or increases the frequency, rate or extent of endothelial cell chemotaxis.
38034	signal transduction in absence of ligand	P	A series of molecular signals initiated by the absence of a ligand or the withdrawal of a ligand from a receptor.
38035	G-protein coupled receptor signaling in absence of ligand	P	A series of molecular signals beginning with a G-protein coupled receptor promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex, where the G-protein coupled receptor is not bound to an agonist.
38036	sphingosine-1-phosphate receptor activity	F	Combining with the sphingolipid sphingosine-1-phosphate (S1P), and transmitting the signal across the membrane by activating an associated G-protein.
38037	G-protein coupled receptor dimeric complex	C	A protein complex that contains two G-protein coupled receptors.
38038	G-protein coupled receptor homodimeric complex	C	A protein complex that contains two G-protein coupled receptors (GPCRs) of the same subtype. Formation of a GPCR homodimer may be important for the transport of newly formed receptors to the cell surface, and the function of the receptor.
38039	G-protein coupled receptor heterodimeric complex	C	A protein complex that contains two G-protein coupled receptors (GPCRs) of different subtypes. Formation of a GPCR heterodimer may alter the functional property of the GPCR.
38040	cross-receptor activation within G-protein coupled receptor heterodimer	P	Activation of one protomer of a G-protein coupled receptor (GPCR) heterodimer by the associated subunit. For example, agonist occupancy in one protomer of a GPCR dimer may activate the associated promoter.
38041	cross-receptor inhibition within G-protein coupled receptor heterodimer	P	Inhibition of one protomer of a G-protein coupled receptor (GPCR) heterodimer by the associated subunit. For example, agonist activation of one cytokine receptor can prevent activation of its associated cytokine receptor subunit.
38042	dimeric G-protein coupled receptor signaling pathway	P	A series of molecular signals initiated by an extracellular signal combining with a dimeric receptor on the surface of the target cell, and proceeding with the activated receptor promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. Heterodimeric and homodimeric GPCRs may have different functional properties from those of the respective monomers.
38043	interleukin-5-mediated signaling pathway	P	A series of molecular signals initiated by the binding of interleukin-5 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.
38044	transforming growth factor-beta secretion	P	The regulated release of transforming growth factor-beta (TGF-beta) from a cell into the extracellular region. TGF-beta is mostly secreted as a large latent TGF-beta complex (LLC) containing latency-associated proteins (LAPs) derived from the N-terminal region of the TGF-beta gene product, dimeric TGF-beta and latent TGF-beta binding proteins (LTBPs).
38045	large latent transforming growth factor-beta complex	C	A protein complex containing latency-associated proteins (LAPs), mature disulphide-linked dimeric TGF-beta, and latent TGF-beta binding proteins (LTBPs). TGF-beta is mostly secreted as part of the large latent complex, and must be subsequently released from the LLC in order to bind to cell surface receptors.
38046	enkephalin receptor activity	F	Combining with an enkephalin, and transmitting the signal across the membrane by activating an associated G-protein. A enkephalin is a pentapeptide (Tyr-Gly-Gly-Phe-Met or Tyr-Gly-Gly-Phe-Leu) involved in regulating nociception in the body.
38047	morphine receptor activity	F	Combining with morphine (17-methyl-7,8-didehydro-4,5alpha-epoxymorphinan-3,6alpha-diol), and transmitting the signal across the membrane by activating an associated G-protein.
38048	dynorphin receptor activity	F	Combining with a dynorphin peptide, and transmitting the signal across the membrane by activating an associated G-protein. Dynorphin is any opioid peptide that is generated by cleavage of the precursor protein prodynorphin.
38049	transcription factor activity, ligand-activated RNA polymerase II transcription factor binding	F	Combining with a signal and transmitting the signal to the transcriptional machinery by interacting selectively and non-covalently with an RNA polymerase II transcription factor, which may be a single protein or a complex, in order to modulate transcription. For example, some steroid hormone receptors bind to transcription factor complexes to regulate transcription of genes whose promoters do not contain hormone response elements.
38050	RNA polymerase II transcription factor activity, glucocorticoid-activated sequence-specific DNA binding	F	Combining with a glucocorticoid and transmitting the signal to the transcriptional machinery by interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription by RNA polymerase II.
38051	glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity	F	Combining with a glucocorticoid and transmitting the signal to the transcriptional machinery by interacting selectively and non-covalently with an RNA polymerase II transcription factor, which may be a single protein or a complex, in order to modulate transcription. For example, glucocorticoid-bound receptors can bind to transcription factor complexes to regulate transcription of genes whose promoters do not contain glucocorticoid response elements.
38052	RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding	F	Combining with estrogen and transmitting the signal to the transcriptional machinery by interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription by RNA polymerase II.
38053	transcription factor activity, estrogen-activated RNA polymerase II transcription factor binding	F	Combining with estrogen and transmitting the signal to the transcriptional machinery by interacting selectively and non-covalently with an RNA polymerase II transcription factor, which may be a single protein or a complex, in order to modulate transcription. For example, estrogen-bound receptors can bind to transcription factor complexes to regulate transcription of genes whose promoters do not contain estrogen response elements.
38054	G-protein coupled estrogen receptor activity	F	Combining with estrogen and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.
38055	BMP secretion	P	The controlled release of a member of the BMP family of proteins from a cell.
38056	negative regulation of BMP signaling pathway by negative regulation of BMP secretion	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the BMP signaling pathway by stopping, preventing or reducing the frequency, rate or extent of secretion of a member of the BMP family of proteins from the signaling cell.
38057	TNFSF11 binding	F	Interacting selectively and non-covalently with tumor necrosis factor ligand superfamily member 11 (TNFSF11), a member of the tumor necrosis factor (TNF) cytokine family.
38058	TNFSF11 receptor activity	F	Combining with a tumor necrosis factor ligand superfamily member 11 (TNFSF11) and transmitting the signal across the cell membrane to initiate a change in cell activity or function.
38059	IKKalpha-IKKalpha complex	C	A homodimeric protein complex containing two IkappaB kinase (IKK) alpha subunits.
38060	nitric oxide-cGMP-mediated signaling pathway	P	Any intracellular signal transduction in which the signal is passed on within the cell by nitric oxide (NO) activating soluble guanylyl cyclase (sGC). Includes synthesis of nitric oxide, guanylyl cyclase activity, and downstream effectors that further transmit the signal within the cell following activation by cGMP.
38061	NIK/NF-kappaB signaling	P	The process in which a signal is passed on to downstream components within the cell through the NIK-dependent processing and activation of NF-KappaB. Begins with activation of the NF-KappaB-inducing kinase (NIK), which in turn phosphorylates and activates IkappaB kinase alpha (IKKalpha). IKKalpha phosphorylates the NF-Kappa B2 protein (p100) leading to p100 processing and release of an active NF-KappaB (p52).
38062	protein tyrosine kinase collagen receptor activity	F	Combining with collagen and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: ATP + a protein-L-tyrosine = ADP + a protein-L-tyrosine phosphate.
38063	collagen-activated tyrosine kinase receptor signaling pathway	P	A series of molecular signals initiated by the binding of collagen to a receptor on the surface of the target cell where the receptor possesses tyrosine kinase activity. The pathway ends with regulation of a downstream cellular process, e.g. transcription.
38064	collagen receptor activity	F	Combining with a collagen and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
38065	collagen-activated signaling pathway	P	A series of molecular signals initiated by collagen binding to a cell surface receptor, and ending with regulation of a downstream cellular process, e.g. transcription.
38066	p38MAPK cascade	P	An intracellular protein kinase cascade containing at least a p38 MAPK, a MAPKK and a MAP3K. The cascade can also contain two additional tiers: the upstream MAP4K and the downstream MAP Kinase-activated kinase (MAPKAPK). The kinases in each tier phosphorylate and activate the kinases in the downstream tier to transmit a signal within a cell.
38067	MAP kinase activity involved in cell wall organization or biogenesis	F	Catalysis of the reaction: protein + ATP = protein phosphate + ADP by a mitogen-activated protein kinase, as part of a MAPK signaling cascade that contributes to cell wall organization or biogenesis.
38068	MAP kinase kinase activity involved in cell wall organization or biogenesis	F	Catalysis of the concomitant phosphorylation of threonine (T) and tyrosine (Y) residues in a Thr-Glu-Tyr (TEY) thiolester sequence in a MAP kinase (MAPK) substrate, as part of a MAPK signaling cascade that contributes to cell wall organization or biogenesis.
38069	MAP kinase phosphatase activity involved in regulation of cell wall biogenesis	F	Catalysis of the reaction: a phosphorylated MAP kinase + H2O = a MAP kinase + phosphate, where the MAP kinase (MAPK) is part of a MAPK signaling cascade that contributes to cell wall biogenesis.
38070	MAP kinase kinase kinase activity involved in cell wall organization or biogenesis	F	Catalysis of the phosphorylation and activation of a MAP kinase kinase (MAPKK), as part of a MAPK signaling cascade that contributes to cell wall organization or biogenesis.
38071	MAP kinase activity involved in conjugation with cellular fusion	F	Catalysis of the reaction: protein + ATP = protein phosphate + ADP by a mitogen-activated protein kinase, as part of a MAPK signaling cascade that contributes to conjugation with cellular fusion.
38072	MAP kinase kinase activity involved in conjugation with cellular fusion	F	Catalysis of the concomitant phosphorylation of threonine (T) and tyrosine (Y) residues in a Thr-Glu-Tyr (TEY) thiolester sequence in a MAP kinase (MAPK) substrate, as part of a MAPK signaling cascade that contributes to conjugation with cellular fusion.
38073	MAP kinase kinase kinase activity involved in conjugation with cellular fusion	F	Catalysis of the phosphorylation and activation of a MAP kinase kinase (MAPKK), as part of a MAPK signaling cascade that contributes to cell wall biogenesis.
38074	MAP kinase phosphatase activity involved in regulation of conjugation with cellular fusion	F	Catalysis of the reaction: a phosphorylated MAP kinase + H2O = a MAP kinase + phosphate, where the MAP kinase (MAPK) is part of a MAPK signaling cascade that contributes to conjugation with cellular fusion.
38075	MAP kinase activity involved in innate immune response	F	Catalysis of the reaction: protein + ATP = protein phosphate + ADP by a mitogen-activated protein kinase, as part of a MAPK signaling cascade that contributes to an innate immune response.
38076	MAP kinase kinase activity involved in innate immune response	F	Catalysis of the concomitant phosphorylation of threonine (T) and tyrosine (Y) residues in a Thr-Glu-Tyr (TEY) thiolester sequence in a MAP kinase (MAPK) substrate, as part of a MAPK signaling cascade that contributes to an innate immune response.
38077	MAP kinase kinase kinase activity involved in innate immune response	F	Catalysis of the phosphorylation and activation of a MAP kinase kinase (MAPKK), as part of a MAPK signaling cascade that contributes to an innate immune response.
38078	MAP kinase phosphatase activity involved in regulation of innate immune response	F	Catalysis of the reaction: a phosphorylated MAP kinase + H2O = a MAP kinase + phosphate, where the MAP kinase (MAPK) is part of a MAPK signaling cascade that contributes to an innate immune response.
38079	MAP kinase activity involved in osmosensory signaling pathway	F	Catalysis of the reaction: protein + ATP = protein phosphate + ADP by a mitogen-activated protein kinase, as part of a MAPK signaling cascade that passes on a signal within an osmosensory signaling pathway.
38080	MAP kinase kinase activity involved in osmosensory signaling pathway	F	Catalysis of the concomitant phosphorylation of threonine (T) and tyrosine (Y) residues in a Thr-Glu-Tyr (TEY) thiolester sequence in a MAP kinase (MAPK) substrate, as part of a MAPK signaling cascade that passes on a signal within an osmosensory signaling pathway.
38081	MAP kinase kinase kinase activity involved in osmosensory signaling pathway	F	Catalysis of the phosphorylation and activation of a MAP kinase kinase (MAPKK), as part of a MAPK signaling cascade that passes on a signal within an osmosensory signaling pathway.
38082	MAP kinase phosphatase activity involved in regulation of osmosensory signaling pathway	F	Catalysis of the reaction: a phosphorylated MAP kinase + H2O = a MAP kinase + phosphate, where the MAP kinase (MAPK) is part of a MAPK signaling cascade that passes on a signal within an osmosensory signaling pathway.
38083	peptidyl-tyrosine autophosphorylation	P	The phosphorylation by a protein of one or more of its own tyrosine amino acid residues, or a tyrosine residue on an identical protein.
38084	vascular endothelial growth factor signaling pathway	P	A series of molecular signals initiated by the binding of a vascular endothelial growth factor (VEGF) to a receptor on the surface of the target cell, and ending with regulation of a downstream cellular process, e.g. transcription.
38085	vascular endothelial growth factor binding	F	Interacting selectively and non-covalently with a vascular endothelial growth factor.
38086	VEGF-activated platelet-derived growth factor receptor signaling pathway	P	A series of molecular signals initiated by the binding of a vascular endothelial growth factor (VEGF) to a platelet-derived growth factor receptor (PDGFR) on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.
38087	VEGF-activated platelet-derived growth factor receptor-alpha signaling pathway	P	A series of molecular signals initiated by the binding of a vascular endothelial growth factor (VEGF) to an alpha-type platelet-derived growth factor receptor (PDGFR) on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.
38088	VEGF-activated platelet-derived growth factor receptor-beta signaling pathway	P	A series of molecular signals initiated by the binding of a vascular endothelial growth factor (VEGF) to a beta-type platelet-derived growth factor receptor (PDGFR) on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.
38089	positive regulation of cell migration by vascular endothelial growth factor signaling pathway	P	A series of molecular signals initiated by the binding of a vascular endothelial growth factor (VEGF) to a receptor on the surface of a cell, which activates or increases the frequency, rate or extent of the orderly movement of a cell from one site to another.
38090	positive regulation of cell migration by VEGF-activated platelet derived growth factor receptor signaling pathway	P	A series of molecular signals initiated by the binding of a vascular endothelial growth factor (VEGF) to a platelet-derived growth factor receptor (PDGFR) on the surface of a cell, which activates or increases the frequency, rate or extent of the orderly movement of a cell from one site to another.
38091	positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway	P	A series of molecular signals initiated by the binding of a vascular endothelial growth factor (VEGF) to a platelet-derived growth factor receptor (PDGFR) on the surface of a cell, which activates or increases the frequency, rate or extent of cell proliferation.
38092	nodal signaling pathway	P	A series of molecular signals initiated by the binding of a nodal protein to an activin receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.
38093	Fc receptor signaling pathway	P	A series of molecular signals initiated by the binding of the Fc portion of an immunoglobulin to an Fc receptor on the surface of a signal-receiving cell, and ending with regulation of a downstream cellular process, e.g. transcription. The Fc portion of an immunoglobulin is its C-terminal constant region.
38094	Fc-gamma receptor signaling pathway	P	A series of molecular signals initiated by the binding of the Fc portion of immunoglobulin G (IgG) to an Fc-gamma receptor on the surface of a signal-receiving cell, and ending with regulation of a downstream cellular process, e.g. transcription. The Fc portion of an immunoglobulin is its C-terminal constant region.
38095	Fc-epsilon receptor signaling pathway	P	A series of molecular signals initiated by the binding of the Fc portion of immunoglobulin E (IgE) to an Fc-epsilon receptor on the surface of a signal-receiving cell, and ending with regulation of a downstream cellular process, e.g. transcription. The Fc portion of an immunoglobulin is its C-terminal constant region.
38096	Fc-gamma receptor signaling pathway involved in phagocytosis	P	An Fc-gamma receptor signaling pathway that contributes to the endocytic engulfment of external particulate material by phagocytes.
38097	positive regulation of mast cell activation by Fc-epsilon receptor signaling pathway	P	An Fc-epsilon receptor signaling pathway that results in the change in morphology and behavior of a mast cell resulting from exposure to a cytokine, chemokine, soluble factor, or to (at least in mammals) an antigen which the mast cell has specifically bound via IgE bound to Fc-epsilonRI receptors.
38098	sequestering of BMP from receptor via BMP binding	P	Binding to a bone morphogenetic protein (BMP) in the extracellular region, and inhibiting BMP signaling by preventing BMP from binding to its cell surface receptor.
38099	nodal receptor complex assembly	P	The aggregation, arrangement and bonding together of a set of components to form a complex containing a type II activin receptor, a type I activin receptor, and a coreceptor of the EGF-CFC family (e.g. Cripto or Cryptic, in mammals).
38100	nodal binding	F	Interacting selectively and non-covalently with a nodal protein, a member of the transforming growth factor-beta superfamily.
38101	sequestering of nodal from receptor via nodal binding	P	Binding to a nodal protein in the extracellular region, and inhibiting nodal signaling by preventing nodal from binding to its cell surface receptor.
38102	activin receptor antagonist activity	F	Interacting with an activin receptor complex to reduce the action of another ligand, the agonist. A receptor antagonist does not initiate signaling upon binding to a receptor, but instead blocks an agonist from binding to the receptor.
38103	activin receptor antagonist activity involved in negative regulation of nodal signaling pathway	F	Interacting with an activin receptor to reduce the action of the agonist nodal. A receptor antagonist does not initiate signaling upon binding to a receptor, but instead blocks an agonist from binding to the receptor.
38104	nodal receptor complex	C	A protein complex containing at least a type II activin receptor, a type I activin receptor, and a coreceptor (EGF-CFC protein) such as Cripto or Cryptic. Nodal receptor complexes are capable of binding a nodal protein and transducing the signal into the cell.
38105	sequestering of TGFbeta from receptor via TGFbeta binding	P	Binding to a transforming growth factor-beta (TGFbeta) protein in the extracellular region, and inhibiting TGFbeta signaling by preventing TGFbeta from binding to its cell surface receptor.
38106	choriogonadotropin hormone binding	F	Interacting selectively and non-covalently with choriogonadotropin hormone, a heterodimer, with an alpha subunit identical to that of luteinizing hormone (LH), follicle-stimulating hormone (FSH) and thyroid-stimulating hormone (TSH), and a unique beta subunit.
38107	nodal signaling pathway involved in determination of left/right asymmetry	P	A series of molecular signals initiated by the binding of a nodal protein to an activin receptor on the surface of a target cell, which contributes to the establishment of an organism's body plan or part of an organism with respect to the left and right halves.
38108	negative regulation of appetite by leptin-mediated signaling pathway	P	A series of molecular signals initiated by the binding of leptin to a receptor on the surface of a cell, which reduces appetite, the desire or physical craving for food.
38109	Kit signaling pathway	P	A series of molecular signals that starts with the binding of stem cell factor to the tyrosine kinase receptor KIT on the surface of a cell, and ends with regulation of a downstream cellular process, e.g. transcription. Stem cell factor (KIT ligand) binding to the receptor Kit mediates receptor dimerization, activation of its intrinsic tyrosine kinase activity and autophosphorylation. The activated receptor then phosphorylates various substrates, thereby activating distinct signaling cascades within the cell that trigger a change in state or activity of the cell.
38110	interleukin-2-mediated signaling pathway	P	A series of molecular signals initiated by the binding of interleukin-2 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.
38111	interleukin-7-mediated signaling pathway	P	A series of molecular signals initiated by the binding of interleukin-7 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.
38112	interleukin-8-mediated signaling pathway	P	A series of molecular signals initiated by the binding of interleukin-8 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.
38113	interleukin-9-mediated signaling pathway	P	A series of molecular signals initiated by the binding of interleukin-9 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.
38114	interleukin-21-mediated signaling pathway	P	A series of molecular signals initiated by the binding of interleukin-21 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.
38115	chemokine (C-C motif) ligand 19 signaling pathway	P	A series of molecular signals initiated by the binding of the C-C chemokine CCL19 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.
38116	chemokine (C-C motif) ligand 21 signaling pathway	P	A series of molecular signals initiated by the binding of the C-C chemokine CCL21 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.
38117	C-C motif chemokine 19 receptor activity	F	Combining with the C-C motif chemokine 19 (CCL19) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
38118	C-C chemokine receptor CCR7 signaling pathway	P	A series of molecular signals initiated by a the C-C chemokine type 7 receptor on the surface of a cell binding to one of it's physiological ligands, and ending with regulation of a downstream cellular process, e.g. transcription.
38119	CCL19-activated CCR7 signaling pathway	P	A series of molecular signals initiated by the binding of the C-C chemokine CCL19 to a C-C chemokine type 7 receptor (CCR7) on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.
38120	CCL21-activated CCR7 signaling pathway	P	A series of molecular signals initiated by the binding of the C-C chemokine CCL21 to a C-C chemokine type 7 receptor (CCR7) on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.
38121	C-C motif chemokine 21 receptor activity	F	Combining with the C-C motif chemokine 21 (CCL21) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
38122	C-C motif chemokine 5 receptor activity	F	Combining with the C-C motif chemokine 5 (CCL5) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
38123	toll-like receptor TLR1:TLR2 signaling pathway	P	A series of molecular signals initiated by the binding of a heterodimeric TLR1:TLR2 complex to one of it's physiological ligands, followed by transmission of the signal by the activated receptor, and ending with regulation of a downstream cellular process, e.g. transcription.
38124	toll-like receptor TLR6:TLR2 signaling pathway	P	A series of molecular signals initiated by the binding of a heterodimeric TLR6:TLR2 complex to one of it's physiological ligands, followed by transmission of the signal by the activated receptor, and ending with regulation of a downstream cellular process, e.g. transcription.
38127	ERBB signaling pathway	P	A series of molecular signals initiated by binding of a ligand to a member of the ERBB family of receptor tyrosine kinases on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.
38128	ERBB2 signaling pathway	P	A series of molecular signals initiated by binding of a ligand to a member of the ERBB family of receptors on the surface of a cell, where the signal is transmitted by ERBB2. The pathway ends with regulation of a downstream cellular process, e.g. transcription. ERBB2 receptors are themselves unable to bind to ligands, but act as a signal-amplifying tyrosine kinase within a heterodimeric pair.
38129	ERBB3 signaling pathway	P	A series of molecular signals initiated by binding of a ligand to the tyrosine kinase receptor ERBB3 on the surface of a cell. The pathway ends with regulation of a downstream cellular process, e.g. transcription. ERBB3 receptors have impaired kinase activity and rely on the kinase activity of the heterodimer partner for activation and signal transmission.
38130	ERBB4 signaling pathway	P	A series of molecular signals initiated by binding of a ligand to the tyrosine kinase receptor ERBB4 on the surface of a cell. The pathway ends with regulation of a downstream cellular process, e.g. transcription.
38131	neuregulin receptor activity	F	Combining with a neuregulin, a member of the EGF family of growth factors, and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
38132	neuregulin binding	F	Interacting selectively and non-covalently with a neuregulin, a member of the EGF family of growth factors.
38133	ERBB2-ERBB3 signaling pathway	P	A series of molecular signals initiated by binding of a ligand to a ERBB3 receptor on the surface of a cell, followed by transmission of the signal by a heterodimeric complex of ERBB2 and ERBB3. ERBB2, which does not bind any known ligand, is activated through formation of a heterodimer with another ligand-activated ERBB family member such as ERBB3. ERBB3 also has impaired kinase activity and relies on ERBB2 for activation and signal transmission.
38134	ERBB2-EGFR signaling pathway	P	A series of molecular signals initiated by binding of a ligand to an epidermal growth factor receptor (EGFR/ERBB1) on the surface of a cell, followed by transmission of the signal by a heterodimeric complex of ERBB2 and EGFR. ERBB2, which does not bind any known ligand, is activated through formation of a heterodimer with another ligand-activated ERBB family member such as EGFR.
38135	ERBB2-ERBB4 signaling pathway	P	A series of molecular signals initiated by binding of a ligand to a ERBB4 receptor on the surface of a cell, followed by transmission of the signal by a heterodimeric complex of ERBB2 and ERBB4. ERBB2, which does not bind any known ligand, is activated through formation of a heterodimer with another ligand-activated ERBB family member such as ERBB4.
38136	ERBB3-ERBB4 signaling pathway	P	A series of molecular signals transmitted by a heterodimeric complex of the tyrosine kinase receptors ERBB3 and ERBB4. The pathway begins with binding of a ligand to either cell surface receptor, or the dimeric receptor complex, and ends with regulation of a downstream cellular process, e.g. transcription.
38137	ERBB4-EGFR signaling pathway	P	A series of molecular signals transmitted by a heterodimeric complex of the tyrosine kinase receptors EGFR (epidermal growth factor receptor/ERBB1) and ERBB4. The pathway begins with binding of a ligand to either cell surface receptor, or the dimeric receptor complex, and ends with regulation of a downstream cellular process, e.g. transcription.
38138	ERBB4-ERBB4 signaling pathway	P	A series of molecular signals initiated by binding of a ligand to the tyrosine kinase receptor ERBB4, followed by ligand-induced homodimerization of ERBB4 and transmission of the signal into the cell by the homodimeric ERBB4 complex. The pathway ends with regulation of a downstream cellular process, e.g. transcription.
38139	ERBB4-EGFR complex	C	A heterodimeric complex between the tyrosine kinase receptors ERBB4 (also called HER4) and epidermal growth factor receptor (EGFR/ERBB1).
38140	ERBB4-ERBB3 complex	C	A heterodimeric complex between the tyrosine kinase receptors ERBB4 (also called HER4) and ERBB3 (also called HER3). ERBB3 has impaired kinase activity so relies on the kinase activity of its heterodimer partner for activation and signal transmission.
38141	ERBB4-ERBB4 complex	C	A homodimeric complex containing two monomers of the tyrosine kinase receptor ERBB4 (also called HER4).
38142	EGFR:ERBB2 complex	C	A heterodimeric complex between the tyrosine kinase receptor ERBB2 and a ligand-activated epidermal growth factor receptor (EGFR/ERBB1). ERBB2, which does not bind any known ligand, is activated through formation of a heterodimer with another ligand-activated ERBB family member such as EGFR.
38143	ERBB3:ERBB2 complex	C	A heterodimeric complex between the tyrosine kinase receptor ERBB2 and a ligand-activated receptor ERBB3. ERBB2, which does not bind any known ligand, is activated through formation of a heterodimer with another ligand-activated ERBB family member such as ERBB3.
38144	ERBB4:ERBB2 complex	C	A heterodimeric complex between the tyrosine kinase receptor ERBB2 and a ligand-activated receptor ERBB4. ERBB2, which does not bind any known ligand, is activated through formation of a heterodimer with another ligand-activated ERBB family member such as ERBB4.
38145	macrophage colony-stimulating factor signaling pathway	P	A series of molecular signals initiated by the binding of the cytokine macrophage colony-stimulating factor (M-CSF) to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.
38146	chemokine (C-X-C motif) ligand 12 signaling pathway	P	A series of molecular signals initiated by the binding of the chemokine CXCL12 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.
38147	C-X-C motif chemokine 12 receptor activity	F	Combining with the C-X-C motif chemokine 12 (CXCL12) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
38148	chemokine (C-C motif) ligand 2 signaling pathway	P	A series of molecular signals initiated by the binding of the C-C chemokine CCL2 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.
38149	C-C motif chemokine 2 receptor activity	F	Combining with the C-C motif chemokine 2 (CCL2) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
38150	C-C chemokine receptor CCR2 signaling pathway	P	A series of molecular signals initiated by a the C-C chemokine type 2 receptor (CCR2) on the surface of a cell binding to one of it's physiological ligands, and ending with regulation of a downstream cellular process, e.g. transcription.
38151	CCL2-activated CCR2 signaling pathway	P	A series of molecular signals initiated by the binding of the C-C chemokine CCL2 to a C-C chemokine type 2 receptor (CCR2) on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.
38152	C-C chemokine receptor CCR4 signaling pathway	P	A series of molecular signals initiated by a the C-C chemokine type 2 receptor (CCR4) on the surface of a cell binding to one of it's physiological ligands, and ending with regulation of a downstream cellular process, e.g. transcription.
38153	CCL2-activated CCR4 signaling pathway	P	A series of molecular signals initiated by the binding of the C-C chemokine CCL2 to a C-C chemokine type 4 receptor (CCR4) on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.
38154	interleukin-11-mediated signaling pathway	P	A series of molecular signals initiated by the binding of interleukin-11 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.
38155	interleukin-23-mediated signaling pathway	P	A series of molecular signals initiated by the binding of interleukin-23 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.
38156	interleukin-3-mediated signaling pathway	P	A series of molecular signals initiated by the binding of interleukin-3 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.
38157	granulocyte-macrophage colony-stimulating factor signaling pathway	P	A series of molecular signals initiated by the binding of the cytokine granulocyte macrophage colony-stimulating factor (GM-CSF) to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. GM-CSF binds to a heterodimer receptor (CSF2R) consisting of an alpha ligand-binding subunit, and a common beta subunit that is shared with other cytokine receptors.
38158	granulocyte colony-stimulating factor signaling pathway	P	A series of molecular signals initiated by the binding of the cytokine granulocyte colony-stimulating factor (G-CSF) to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. G-CSF binds to the receptor (CSF3R).
38159	C-X-C chemokine receptor CXCR4 signaling pathway	P	A series of molecular signals initiated by a the C-X-C chemokine type 4 receptor on the surface of a cell binding to one of it's physiological ligands, and ending with regulation of a downstream cellular process, e.g. transcription.
38160	CXCL12-activated CXCR4 signaling pathway	P	A series of molecular signals initiated by the binding of the C-X-C chemokine CXCL12 to a C-X-C chemokine type 4 receptor (CXCR4) on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.
38161	prolactin signaling pathway	P	A series of molecular signals initiated by the binding of the peptide hormone prolactin to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.
38162	erythropoietin-mediated signaling pathway	P	A series of molecular signals initiated by the binding of erythropoietin (EPO) to the erythropoietin receptor (EPO-R) on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.
38163	thrombopoietin-mediated signaling pathway	P	A series of molecular signals initiated by the binding of a thrombopoietin to the thrombopoietin receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.
38164	thrombopoietin receptor activity	F	Combining with the glycoprotein thrombopoietin and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
38165	oncostatin-M-mediated signaling pathway	P	A series of molecular signals initiated by the binding of oncostatin-M (OSM) to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. OSM can signal via at least two different receptors (a specific receptor and a LIF receptor) to activate different downstream signal transduction pathways.
38166	angiotensin-activated signaling pathway	P	The series of molecular signals generated as a consequence of angiotensin II binding to an angiotensin receptor on the surface of the cell, and proceeding with the activated receptor transmitting the signal to a heterotrimeric G-protein complex to initiate a change in cell activity. Ends with regulation of a downstream cellular process, e.g. transcription.
38167	epidermal growth factor receptor signaling pathway via positive regulation of NF-kappaB transcription factor activity	P	The series of molecular signals generated as a consequence of an epidermal growth factor receptor binding to one of its physiological ligands, where the signal is passed on within the cell via activation of the transcription factor NF-kappaB.
38168	epidermal growth factor receptor signaling pathway via I-kappaB kinase/NF-kappaB cascade	P	The series of molecular signals generated as a consequence of an epidermal growth factor receptor binding to one of its physiological ligands, where the signal is passed on within the cell via I-kappaB-kinase (IKK)-dependent activation of the transcription factor NF-kappaB.
38169	somatostatin receptor signaling pathway	P	The series of molecular signals generated as a consequence of a somatostatin receptor (SSTR) binding to one of its physiological ligands and transmitting the signal to a heterotrimeric G-protein complex. The pathway ends with regulation of a downstream cellular process, e.g. transcription.
38170	somatostatin signaling pathway	P	The series of molecular signals generated as a consequence of the peptide somatostatin (SST) binding to a somatostatin receptor (SSTR). The pathway proceeds with the receptor transmitting the signal to a heterotrimeric G-protein complex and ends with regulation of a downstream cellular process, e.g. transcription.
38171	cannabinoid signaling pathway	P	The series of molecular signals generated as a consequence of a cannabinoid binding to a cell surface receptor. The pathway proceeds with the receptor transmitting the signal to a heterotrimeric G-protein complex and ends with regulation of a downstream cellular process, e.g. transcription. Cannabinoids are a class of diverse chemical compounds that include the endocannabinoids and the phytocannabinoids.
38172	interleukin-33-mediated signaling pathway	P	A series of molecular signals initiated by the binding of interleukin-33 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.
38173	interleukin-17A-mediated signaling pathway	P	A series of molecular signals initiated by the binding of interleukin-17A to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.
38174	interleukin-17A receptor activity	F	Combining with the cytokine interleukin-17A and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
38175	negative regulation of SREBP signaling pathway in response to increased oxygen levels	P	Any process that stops, prevents or reduces the frequency, rate or extent of the SREBP signaling pathway in response to an increase in oxygen levels.
38176	positive regulation of SREBP signaling pathway in response to decreased oxygen levels	P	Any process that activates or increases the frequency, rate or extent of the SREBP signaling pathway in response to a decrease in oxygen levels.
38177	death receptor agonist activity	F	Interacting with a death receptor such that the proportion of death receptors in an active form is increased. Ligand binding to a death receptor often induces a conformational change to activate the receptor.
38178	complement component C5a signaling pathway	P	A series of molecular signals generated as a consequence of a the C5a component of the complement pathway binding to a complement receptor, and ending with regulation of a downstream cellular process. C5a is a peptide derived from the C5 complement factor.
38179	neurotrophin signaling pathway	P	A series of molecular signals initiated by the binding of a neurotrophin to a receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription. Neurotrophins are a family of secreted growth factors that induce the survival, development, and function of neurons.
38180	nerve growth factor signaling pathway	P	A series of molecular signals initiated by the binding of nerve growth factor (NGF) to a receptor on the surface of the target cell, and ending with regulation of a downstream cellular process, e.g. transcription.
38181	bile acid receptor activity	F	Combining with a bile acid and transmitting the signal to initiate a change in cell activity. A bile acid is any member of a group of steroid carboxylic acids occurring in bile.
38182	G-protein coupled bile acid receptor activity	F	Combining with an extracellular bile acid and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.
38183	bile acid signaling pathway	P	A series of molecular signals initiated by the binding of a bile acid to a receptor, and ending with regulation of a downstream cellular process, e.g. transcription.
38184	cell surface bile acid receptor signaling pathway	P	A series of molecular signals initiated by binding of a bile acid to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.
38185	intracellular bile acid receptor signaling pathway	P	A series of molecular signals initiated by a bile acid binding to an receptor located within a cell, and ending with regulation of a downstream cellular process, e.g. transcription.
38186	lithocholic acid receptor activity	F	Combining with lithocholic acid and transmitting the signal to initiate a change in cell activity.
38187	pattern recognition receptor activity	F	Combining with a pathogen-associated molecular pattern (PAMP), a structure conserved among microbial species, or damage-associated molecular pattern (DAMP), an endogenous molecule released from damaged cells), to initiate a change in cell activity.
38188	cholecystokinin signaling pathway	P	The series of molecular signals generated as a consequence of cholecystokinin binding to a receptor on the surface of the cell, and proceeding with the activated receptor transmitting the signal to a heterotrimeric G-protein complex to initiate a change in cell activity. Ends with regulation of a downstream cellular process, e.g. transcription.
38189	neuropilin signaling pathway	P	A series of molecular signals initiated by the binding of an extracellular ligand to an neuropilin protein on the surface of a target cell, followed by transmission of the signal, and ending with regulation of a downstream cellular process, e.g. transcription.
38190	VEGF-activated neuropilin signaling pathway	P	A series of molecular signals initiated by the binding of vascular endothelial growth factor (VEGF) to a neuropilin protein on the surface of a target cell, followed by transmission of the signal, and ending with regulation of a downstream cellular process, e.g. transcription.
38191	neuropilin binding	F	Interacting selectively and non-covalently with a member of the neuropilin family.
38192	gastric inhibitory peptide signaling pathway	P	The series of molecular signals generated as a consequence of a gastric inhibitory peptide (GIP) binding to a cell surface receptor. The pathway proceeds with the receptor transmitting the signal to a heterotrimeric G-protein complex and ends with regulation of a downstream cellular process, e.g. transcription.
38193	thromboxane A2 signaling pathway	P	The series of molecular signals generated as a consequence of thromboxane A2 binding to a cell surface receptor. The pathway proceeds with the receptor transmitting the signal to a heterotrimeric G-protein complex and ends with regulation of a downstream cellular process, e.g. transcription.
38194	thyroid-stimulating hormone signaling pathway	P	The series of molecular signals generated as a consequence of thyroid-stimulating hormone (thyrotropin) binding to a cell surface receptor. The pathway proceeds with the receptor transmitting the signal to a heterotrimeric G-protein complex and ends with regulation of a downstream cellular process, e.g. transcription.
38195	urokinase plasminogen activator signaling pathway	P	A series of molecular signals initiated by the binding of urokinase plasminogen activator to a receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.
38196	type III interferon signaling pathway	P	A series of molecular signals initiated by the binding of a type III interferon to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. Interferon lambda is the only member of the type III interferon found so far.
38197	type I interferon receptor complex	C	A heterodimeric protein complex that binds a type I interferon and transmits the signal across the membrane into the cell. Consists of an alpha subunit (IFNAR1) and a beta subunit (IFNAR2).
38198	auxin receptor activity	F	Combining with auxin and transmitting the signal in the cell to initiate a change in cell activity. Auxin is a plant hormone (phytohormone).
38199	ethylene receptor activity	F	Combining with ethylene and transmitting the signal in the cell to initiate a change in cell activity.
38200	ethylene receptor histidine kinase activity	F	Combining with ethylene and transmitting the signal within the cell to initiate a change in cell activity by catalysis of the reaction: ATP + a protein-L-histidine = ADP + a protein-L-histidine phosphate.
38201	TOR complex	C	A protein complex that contains at least TOR (target of rapamycin) in complex with other signaling components. Mediates the phosphorylation and activation of downstream signaling components including PKB (AKT) or S6K.
38202	TORC1 signaling	P	A series of intracellular molecular signals mediated by TORC1; TOR (target of rapamycin) in complex with at least Raptor (regulatory-associated protein of TOR), or orthologs of, and other signaling components.
38203	TORC2 signaling	P	A series of intracellular molecular signals mediated by TORC2; TOR (rapamycin-insensitive companion of TOR) in complex with at least Rictor (regulatory-associated protein of TOR), or orthologs of, and other signaling components.
39003	pronephric field specification	P	The process in which regions of the embryo are delineated into the area in which the pronephric kidney will develop.
39004	specification of pronephric proximal tubule identity	P	The process in which the proximal tubule of the pronephric nephron acquires its identity.
39005	specification of pronephric tubule identity	P	The process in which the tubules arranged along the proximal/distal axis of the pronephric nephron acquire their identity.
39006	pronephric nephron tubule formation	P	The developmental process pertaining to the initial formation of a pronephric nephron tubule from unspecified parts. A pronephric nephron tubule is an epithelial tube that is part of a nephron in the pronephros.
39007	pronephric nephron morphogenesis	P	The process in which the anatomical structures of the pronephric nephron are generated and organized. A pronephric nephron is the functional unit of the pronephros.
39008	pronephric nephron tubule morphogenesis	P	The process in which the anatomical structures of a pronephric nephron tubule are generated and organized from an epithelium. A pronephric nephron tubule is an epithelial tube that is part of the pronephric nephron.
39009	rectal diverticulum development	P	The process whose specific outcome is the progression of the rectal diverticulum over time, from its formation to the mature structure. The rectal diverticulum is an outgrowth of the cloaca and links the pronephric kidney to the exterior.
39010	specification of pronephric distal tubule identity	P	The process in which the distal tubule of the pronephric nephron acquires its identity.
39011	pronephric proximal tubule morphogenesis	P	The process in which the anatomical structures of a pronephric nephron proximal tubule are generated and organized. A pronephric nephron tubule is an epithelial tube that is part of the pronephros.
39012	pronephric sinus development	P	The process whose specific outcome is the progression of the pronephric sinus over time, from its formation to the mature structure. The pronephric sinus is an ill-defined capillary network that lies between the pronephric tubules.
39013	pronephric distal tubule morphogenesis	P	The process in which the anatomical structures of a pronephric nephron distal tubule are generated and organized. A pronephric nephron tubule is an epithelial tube that is part of the pronephros.
39014	cell differentiation involved in pronephros development	P	The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the pronephros as it progresses from its formation to the mature state.
39015	cell proliferation involved in pronephros development	P	The multiplication or reproduction of cells, resulting in the expansion of the population in the pronephros.
39016	cell-cell signaling involved in pronephros development	P	Any process that mediates the transfer of information from one cell to another and contributes to the progression of the pronephros over time, from its formation to the mature organ.
39017	pattern specification involved in pronephros development	P	Any developmental process that results in the creation of defined areas or spaces within the pronephros to which cells respond and eventually are instructed to differentiate.
39018	nephrostome development	P	The process whose specific outcome is the progression of the nephrostome over time, from its formation to the mature structure. The nephrostome is the opening of the pronephros into the body cavity.
39019	pronephric nephron development	P	The process whose specific outcome is the progression of the pronephric nephron over time, from its formation to the mature structure. A pronephric nephron is the functional unit of the pronephros.
39020	pronephric nephron tubule development	P	The process whose specific outcome is the progression of a pronephric nephron tubule over time, from its formation to the mature structure. The pronephric nephron tubule is an epithelial tube that is part of the pronephric nephron and connects the filtration unit (glomerulus or glomus) of the pronephros to the pronephric duct.
39021	pronephric glomerulus development	P	The progression of the glomerulus of the pronephric kidney over time from its initial formation until its mature state. The pronephric glomerulus is part of the pronephric nephron and is restricted to one body segment.
39022	pronephric duct development	P	The process whose specific outcome is the progression of the pronephric duct over time, from its formation to the mature structure. The pronephric duct collects the filtrate from the pronephric tubules and opens to the exterior of the pronephric kidney.
39023	pronephric duct morphogenesis	P	The process in which the anatomical structures of the pronephric duct are generated and organized. The pronephric duct collects the filtrate from the pronephric tubules and opens to the exterior of the kidney.
39501	suppression by virus of host type I interferon production	P	Any viral process that results in the inhibition of host cell type I interferon production. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families.
39502	suppression by virus of host type I interferon-mediated signaling pathway	P	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of type I interferon-mediated signaling in the host organism. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families.
39503	suppression by virus of host innate immune response	P	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of the innate immune response of the host organism, the host's first line of defense.
39504	suppression by virus of host adaptive immune response	P	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of the adaptive immune response of the host organism, an immune response based on directed amplification of specific receptors for antigen produced through a somatic diversification process, and allowing for enhanced response to subsequent exposures to the same antigen (immunological memory).
39505	suppression by virus of host antigen processing and presentation of peptide antigen via MHC class II	P	Any viral process that inhibits a host antigen-presenting cell expressing a peptide antigen on its cell surface in association with an MHC class II protein complex.
39506	modulation by virus of host molecular function	P	The process in which a virus effects a change in the function of a host protein via a direct interaction.
39507	suppression by virus of host molecular function	P	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of the functional activity of a host protein.
39508	suppression by virus of host receptor activity	P	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of the functional activity of a host receptor.
39509	suppression by virus of host pattern recognition receptor activity	P	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of the functional activity of a host pattern recognition receptor. A pattern recognition receptor combines with a molecular pattern based on a repeating or polymeric structure, such as a polysaccharide or peptidoglycan, to initiate a change in cell activity.
39510	suppression by virus of host ATP-dependent RNA helicase activity	P	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host ATP-dependent RNA helicase activity.
39511	suppression by virus of host interferon receptor activity	P	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of the functional activity of a host interferon receptor.
39512	suppression by virus of host protein tyrosine kinase activity	P	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host protein tyrosine kinase activity.
39513	suppression by virus of host catalytic activity	P	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host enzyme activity.
39514	suppression by virus of host JAK-STAT cascade	P	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of the JAK-STAT signal cascade in the host organism.
39516	modulation by virus of host catalytic activity	P	The process in which a virus effects a change in host enzyme activity.
39517	modulation by virus of host protein serine/threonine phosphatase activity	P	The process in which a virus effects a change in host protein serine/threonine phosphatase activity.
39518	suppression by virus of host cytokine activity	P	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host cytokine activity.
39519	modulation by virus of host autophagy	P	Any process in which a virus effect a change in the frequency, rate or extent of autophagy in the host.
39520	induction by virus of host autophagy	P	Any process in which a virus activates or increases the frequency, rate or extent of autophagy in the host.
39521	suppression by virus of host autophagy	P	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of autophagy in the host.
39522	suppression by virus of host mRNA export from nucleus	P	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of movement of mRNA from the nucleus to the cytoplasm in the host organism.
39523	suppression by virus of host RNA polymerase II activity	P	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host RNA polymerase II activity.
39524	suppression by virus of host mRNA processing	P	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of mRNA processing in the host cell. mRNA processing is the conversion of a primary mRNA transcript into one or more mature mRNA(s) prior to translation into polypeptide.
39525	modulation by virus of host chromatin organization	P	Any process in which a virus effects a change in the organization of chromatin in the host.
39526	modulation by virus of host apoptotic process	P	Any process in which a virus modulates the frequency, rate or extent of apoptosis of infected host cells.
39527	suppression by virus of host TRAF-mediated signal transduction	P	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of TRAF-mediated signal transduction in the host.
39528	cytoplasmic pattern recognition receptor signaling pathway in response to virus	P	Any series of molecular signals generated as a consequence of a virus or viral RNA binding to a pattern recognition receptor (PRR) located in the cytoplasm. Cytosolic PRRs such as RIG-I (DDX58) and MDA-5 (IFIH1) detect RNA synthesized during active viral replication and trigger a signaling pathway to protect the host against viral infection, for example by inducing the expression of antiviral cytokines.
39529	RIG-I signaling pathway	P	Any series of molecular signals generated as a consequence of the cytoplasmic pattern recognition receptor (PRR) RIG-1 (also known as DDX58) binding to viral RNA. RIG-I detects RNA synthesized during active viral replication and triggers a signaling pathway to protect the host against viral infection, for example by inducing the expression of antiviral cytokines.
39530	MDA-5 signaling pathway	P	Any series of molecular signals generated as a consequence of the cytoplasmic pattern recognition receptor (PRR) MDA-5 (also known as IFIH1) binding to viral RNA. MDA-5 detects RNA synthesized during active viral replication and triggers a signaling pathway to protect the host against viral infection, for example by inducing the expression of antiviral cytokines.
39531	regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway	P	Any process that modulates the frequency, rate or extent of the series of molecular signals generated as a consequence of a virus or viral RNA binding to a pattern recognition receptor (PRR) located in the cytoplasm.
39532	negative regulation of viral-induced cytoplasmic pattern recognition receptor signaling pathway	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the series of molecular signals generated as a consequence of a virus or viral RNA binding to a pattern recognition receptor (PRR) located in the cytoplasm.
39533	regulation of MDA-5 signaling pathway	P	Any process that modulates the frequency, rate or extent of the series of molecular signals generated as a consequence of the cytoplasmic pattern recognition receptor (PRR) MDA-5 (also known as IFIH1) binding to viral RNA.
39534	negative regulation of MDA-5 signaling pathway	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the series of molecular signals generated as a consequence of the cytoplasmic pattern recognition receptor (PRR) MDA-5 (also known as IFIH1) binding to viral RNA.
39535	regulation of RIG-I signaling pathway	P	Any process that modulates the frequency, rate or extent of the series of molecular signals generated as a consequence of the cytoplasmic pattern recognition receptor (PRR) RIG-1 (also known as DDX58) binding to viral RNA.
39536	negative regulation of RIG-I signaling pathway	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the series of molecular signals generated as a consequence of the cytoplasmic pattern recognition receptor (PRR) RIG-1 (also known as DDX58) binding to viral RNA.
39537	suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway	P	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of the series of molecular signals generated as a consequence of a virus or viral RNA binding to a pattern recognition receptor (PRR) located in the cytoplasm. This is a mechanism by which the virus evades the host innate immune response.
39538	suppression by virus of host RIG-I signaling pathway	P	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of the series of molecular signals generated as a consequence of the cytoplasmic pattern recognition receptor (PRR) RIG-1 (also known as DDX58) binding to viral RNA. This is a mechanism by which the virus evades the host innate immune response.
39539	suppression by virus of host MDA-5 signaling pathway	P	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of the series of molecular signals generated as a consequence of the cytoplasmic pattern recognition receptor (PRR) MDA-5 (also known as IFIH1) binding to viral RNA. This is a mechanism by which the virus evades the host innate immune response.
39540	suppression by virus of host RIG-I activity	P	Any process in which a virus stops, prevents, or reduces the activity of RIG-1 (also known as DDX58). The cytoplasmic pattern recognition RIG-I recognizes viral RNA synthesized during active viral replication and signals to protect the host against viral infection, for example by inducing the expression of antiviral cytokines.
39541	suppression by virus of host RIG-I via RIG-I binding	P	Any process in which a virus stops, prevents, or reduces the activity of RIG-I (also known as DDX58) by interacting selectively and non-covalently with RIG-I itself.
39542	suppression by virus of host RIG-I K63-linked ubiquitination	P	Any process in which a virus stops, prevents, or reduces the rate or extent of K63-linked ubiquitination of RIG-I (also known as DDX58), thereby suppressing RIG-I signal transduction. Lys63-linked ubiquitination of the N-terminal CARD domains of RIG-I is crucial for the cytosolic RIG-I signaling pathway to elicit host antiviral innate immunity.
39543	suppression by virus of host RIG-I activity by viral RNA 5' processing	P	The post-transcriptional removal by a virus of the 5' triphosphate group of their viral RNA, thereby preventing host RIG-I from recognizing viral RNA in the host cell. The intracellular pattern recognition receptor RIG-I (also known as DDX58) recognizes viral RNAs containing 5' triphosphates; removal by the virus of the 5'-terminal triphosphate group from their genome protects the viral RNA from RIG-recognition.
39544	suppression by virus of host RIG-I activity by RIG-I proteolysis	P	The chemical reactions and pathways performed by a virus resulting in the hydrolysis of the host RIG-I protein (also known as DDX58) by cleavage of peptide bonds, thereby inhibiting RIG-I signal transduction.
39545	suppression by virus of host MAVS activity	P	Any process in which a virus stops, prevents, or reduces the activity of MAVS (mitochondrial antiviral signaling protein), a signal transducer that lies downstream of the viral RNA receptors MDA-5 and RIG-I to coordinate host innate immune responses.
39546	suppression by virus of host MAVS activity by MAVS proteolysis	P	The chemical reactions and pathways performed by a virus resulting in the hydrolysis of the host MAVS (mitochondrial inhibitor of viral signaling) protein by cleavage of peptide bonds, thereby inhibiting the host innate immune response. For example, MAVS harbors a C-terminal transmembrane domain that targets it to the mitochondrial outer membrane; cleavage within this domain removes MAVS from the membrane, thus preventing it from signaling.
39547	suppression by virus of host TRAF activity	P	Any process in which a virus stops, prevents, or reduces the activity of a host TRAF (tumor necrosis factor receptor-associated factor) protein. TRAFs are intracellular signal transducers that lie downstream of receptors including RIG-I, MDA-5 and Toll-like receptors (TLR) and transfer the signal to other intracellular signaling components.
39548	suppression by virus of host IRF3 activity	P	Any process in which a virus stops, prevents, or reduces the activity of host IRF3 (interferon regulatory factor-3), a transcription factor in the RIG-I/MDA-5 signaling pathway. Viral infection triggers phosphorylation of cytoplasmic IRF3, which allows IRF3 to form a homodimer, migrate to the nucleus, and activate transcription of IFN-alpha and IFN-beta genes.
39549	suppression by virus of host IRF3 activity by inhibition of IRF3 phosphorylation	P	Any process in which a virus stops, prevents, or reduces the rate or extent of the phosphorylation of IRF3 (interferon regulatory factor-3), thereby inhibiting IRF3 activation. In response to signaling from RIG-1/MDA-5 receptors, IRF3 is phosphorylated on multiple serine and threonine residues; phosphorylation results in the cytoplasm-to-nucleus translocation of IRF3, DNA binding, and increased transcriptional activation of interferon-encoding genes.
39550	suppression by virus of host IRF3 activity by inhibition of DNA binding	P	Any process in which a virus stops, prevents, or reduces IRF3-dependent gene transcription, by preventing or reducing IRF3 binding to promoter sites.
39551	suppression by virus of host IRF3 activity by positive regulation of IRF3 catabolic process	P	Any process in which a virus stops, prevents, or reduces the activity of host IRF3 (interferon regulatory factor-3) by promoting the ubiquitin-dependent degradation of IRF3, mediated by the proteasome.
39552	RIG-I binding	F	Interacting selectively and non-covalently with RIG-I, a cytosolic pattern recognition receptor that initiates an antiviral signaling pathway upon binding to viral RNA.
39553	suppression by virus of host chemokine activity	P	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host chemokine activity.
39554	suppression by virus of host MDA-5 activity	P	Any process in which a virus stops, prevents, or reduces the activity of MDA-5 (also known as IFIH1). The cytoplasmic pattern recognition receptor MDA-5 detects dsRNA synthesized during active viral replication and triggers a signaling pathway to protect the host against viral infection, for example by inducing the expression of antiviral cytokines.
39555	suppression by virus of host MDA-5 activity via MDA-5 binding	P	Any process in which a virus stops, prevents, or reduces the activity of MDA-5 (also known as IFIH1) by interacting selectively and non-covalently with MDA-5 itself. For example, direct binding of viral proteins to the host MDA-5 protein can inhibit interaction of MDA-5 with MAVS, its downstream signaling effector.
39556	MDA-5 binding	F	Interacting selectively and non-covalently with MDA-5, a cytosolic pattern recognition receptor that initiates an antiviral signaling pathway upon binding to viral dsRNA.
39557	suppression by virus of host IRF7 activity	P	Any process in which a virus stops, prevents, or reduces the activity of host IRF7 (interferon regulatory factor-7), a transcription factor in the RIG-I/MDA-5 signaling pathway. Viral infection triggers phosphorylation of cytoplasmic IRF7, which allows IRF7 to form a homodimer, migrate to the nucleus, and activate transcription of IFN-alpha and IFN-beta genes.
39558	suppression by virus of host IRF7 activity by positive regulation of IRF7 sumoylation	P	Any process in which a virus stops, prevents, or reduces IRF7-dependent gene transcription, by promoting the sumoylation of IRF7, thereby disabling its activity.
39559	suppression by virus of host IRF7 activity by positive regulation of IRF7 catabolic process	P	Any process in which a virus stops, prevents, or reduces the activity of host IRF7 (interferon regulatory factor-7) by promoting the ubiquitin-dependent degradation of IRF7, mediated by the proteasome.
39560	suppression by virus of host IRF9 activity	P	Any process in which a virus stops, prevents, or reduces the activity of host IRF9 (interferon regulatory factor-9), a transcription factor involved in the innate immune response. Viral infection triggers binding of IRF9 to phosphorylated STAT1 and STAT2, forming the ISGF3 complex. The ISGF3 complex migrates to the nucleus and activates transcription of IFN-responsive genes.
39561	suppression by virus of host IRF9 activity by positive regulation of IRF9 localization to nucleus	P	Any process in which a virus stops, prevents, or reduces the activity of host IRF9 (interferon regulatory factor-9) by promoting the nuclear accumulation of IRF9. For example, the reovirus mu2 protein promotes nuclear accumulation of host IRF9 by an as yet unconfirmed-mechanism.
39562	suppression by virus of host STAT activity	P	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host STAT (signal transducer and activator of transcription) activity. STATs are SH2 domain-containing proteins which lie downstream of many signaling receptors. Upon phosphorylation by JAKs, STAT proteins hetero- or homo-dimerize and translocate to the nucleus to activate transcription of target genes.
39563	suppression by virus of host STAT1 activity	P	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host STAT1 (signal transducer and activator of transcription-1) activity. STATs are SH2 domain-containing proteins which lie downstream of many signaling receptors. Upon phosphorylation by JAKs, STAT proteins hetero- or homo-dimerize and translocate to the nucleus to activate transcription of target genes.
39564	suppression by virus of host STAT2 activity	P	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host STAT2 (signal transducer and activator of transcription-2) activity. STATs are SH2 domain-containing proteins which lie downstream of many signaling receptors. Upon phosphorylation by JAKs, STAT proteins hetero- or homo-dimerize and translocate to the nucleus to activate transcription of target genes.
39565	suppression by virus of host STAT1 activity by positive regulation of STAT1 catabolic process	P	Any process in which a virus stops, prevents, or reduces the activity of host STAT1 (signal transducer and activator of transcription-1) by promoting the ubiquitin-dependent degradation of STAT1, mediated by the proteasome.
39566	suppression by virus of host STAT1 activity by tyrosine dephosphorylation of STAT1	P	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host STAT1 (signal transducer and activator of transcription-1) activity by the removal of phosphoric residues from STAT1-O-phospho-tyrosine to form STAT1-tyrosine. For example, the viral phosphatase VH1 dephosphorylates STAT1 to reverse STAT1 activation.
39567	suppression by virus of host STAT1 activity by negative regulation of STAT protein import into nucleus	P	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host STAT1 (signal transducer and activator of transcription-1) activity by retaining STAT1 in the cytoplasm, so STAT1 is unable to translocate to the nucleus to activate transcription of its target genes.
39568	suppression by virus of host STAT1 activity by inhibition of DNA binding	P	Any process in which a virus stops, prevents, or reduces STAT1-dependent gene transcription, by preventing STAT1 from binding to promoter sites in the nucleus.
39569	suppression by virus of host STAT2 activity by positive regulation of STAT2 catabolic process	P	Any process in which a virus stops, prevents, or reduces the activity of host STAT2 (signal transducer and activator of transcription-2) by promoting the ubiquitin-dependent degradation of STAT2, mediated by the proteasome.
39570	suppression by virus of host STAT2 activity by negative regulation of STAT protein import into nucleus	P	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host STAT2 (signal transducer and activator of transcription-2) activity by retaining STAT2 in the cytoplasm, so STAT2 is unable to translocate to the nucleus to activate transcription of its target genes.
39571	suppression by virus of host STAT1 activity by negative regulation of STAT1 tyrosine phosphorylation	P	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host STAT1 (signal transducer and activator of transcription-1) activity by stopping, preventing, or reducing the frequency, rate or extent of the introduction of a phosphate group to a tyrosine residue of a STAT1 protein. For example, the measles virus V protein inhibits tyrosine phosphorylation of STAT1, thereby preventing STAT1 activation.
39572	suppression by virus of host STAT2 activity by negative regulation of STAT2 tyrosine phosphorylation	P	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host STAT2 (signal transducer and activator of transcription-2) activity by stopping, preventing, or reducing the frequency, rate or extent of the introduction of a phosphate group to a tyrosine residue of a STAT2 protein. For example, the measles virus V protein inhibits tyrosine phosphorylation of STAT2, thereby preventing STAT2 activation.
39573	suppression by virus of host complement activation	P	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of complement activation. The activation of complement involves the sequential proteolysis of proteins to generate enzymes with catalytic activities. The biological functions of the complement include opsonization, inflammation, lysis of immune complexes, or enhancement of the humoral immune response. For example, the virus complement control protein (VCP) of vaccinia virus, and the complement control protein of herpesvirus inhibit C3 convertase.
39574	suppression by virus of host TYK2 activity	P	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host TYK2 (tyrosine kinase 2) activity. TYK2 is an intracellular signal-transducing tyrosine kinase that associates with the cytoplasmic tails of cytokine receptors and transmits the cytokine signal by phosphorylating receptor subunits.
39575	suppression by virus of host TYK2 activity by negative regulation of TYK2 tyrosine phosphorylation	P	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host TYK2 (tyrosine kinase 2) activity by stopping, preventing or reducing phosphorylation and thereby activation of TYK2.
39576	suppression by virus of host JAK1 activity	P	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host JAK1 (Janus Kinase 1) activity. In the host, binding of a ligand to a receptor triggers activation of JAK proteins, which phosphorylate tyrosine residues on the receptor creating sites for STAT proteins to bind, which are in turn phosphorylated and activated by JAK proteins. By blocking JAK1 activity, many viruses block the host signal transduction pathway.
39577	suppression by virus of host JAK1 activity by negative regulation of JAK1 phosphorylation	P	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host JAK1 (Janus Kinase 1) activity by stopping, preventing or reducing tyrosine phosphorylation of JAK1 and thereby activation of JAK1.
39578	suppression by virus of host JAK1 activity via JAK1 binding	P	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host JAK1 (Janus Kinase 1) activity by interacting directly and selectively with JAK1. For example, the polyoma virus T antigen binds to JAK1 and renders it inactive.
39579	suppression by virus of host ISG15 activity	P	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host ubiquitin-like protein ISG15 activity. ISG15 is a ubiquitin-like protein that is conjugated to lysine residues on various target proteins. Viruses escape from the antiviral activity of ISG15 by using different mechanisms; the influenza B virus NS1 protein for instance blocks the covalent linkage of ISG15 to its target proteins by directly interacting with ISG15. The papain-like protease from the coronavirus cleaves ISG15 derivatives.
39580	suppression by virus of host PKR activity	P	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host PKR (protein kinase regulated by RNA) activity. Activation of PKR involves dsRNA binding followed by autophosphorylation. Phosphorylated PKR can then phosphorylate downstream targets such as the translation initiation factor eIF2 to inhibit protein synthesis. Viruses encode a number of mechanisms to inhibit the host antiviral response via PKR, including direct interaction with PKR, promoting degradation of PKR or altering the subcellular location of PKR.
39581	suppression by virus of host PKR activity via double-stranded RNA binding	P	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host PKR (protein kinase regulated by RNA) activity by interacting selectively and non-covalently with double-stranded RNA (dsRNA). Binding of viral proteins to RNA may sequester or alter the RNA so it can not be recognized by host PKR, or may compete with PKR for dsRNA binding.
39582	suppression by virus of host PKR activity by positive regulation of PKR nuclear localization	P	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host PKR (protein kinase regulated by RNA) activity by promoting the localization of PKR in the nucleus. For example, human cytomegalovirus (HMCV) gene products directly interact with PKR and inhibit its activation by sequestering it in the nucleus, away from both its activator (cytoplasmic dsRNA) and its substrate, (eIF2alpha).
39583	suppression by virus of host PKR activity by positive regulation of PKR catabolic process	P	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host PKR (protein kinase regulated by RNA) activity by promoting the degradation of PKR via the proteosome. For example, the Rift Valley fever virus (RVFV) NSs protein induces the down-regulation of PKR by degradation through proteasomes.
39584	suppression by virus of host protein kinase activity	P	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host protein kinase activity.
39585	PKR signal transduction	P	A series of reactions in which a signal is passed on to downstream proteins within the cell via PKR, an intracellular protein kinase that is activated by stress signals or upon binding to double-stranded RNA (dsRNA), followed by autophosphorylation. PKR plays a role in the antiviral response, phosphorylating proteins such as the translation initiation factor eIF2 to inhibit protein synthesis during viral infection. Begins with activation of PKR activity, and ends with regulation of a downstream cellular process, e.g. regulation of transcription or inhibition of translation.
39586	modulation by virus of host PP1 activity	P	The process in which a virus effects a change in host protein phosphatase-1 (PP1) activity, a serine/threonine phosphatase. Different viruses modulate host PP1 activity to remove phosphates from various cellular substrates and downregulate the host's antiviral response.
39587	suppression by virus of host tetherin activity	P	Any process in which a virus stops, prevents, or reduces the activity of host tetherin activity. Tetherin (also known as BST2) is an alpha interferon-inducible cellular factor that impairs the release of many enveloped viruses. By blocking tetherin activity, many viruses circumvent its antiviral effects.
39588	suppression by virus of host antigen processing and presentation	P	Any viral process that inhibits a host antigen-presenting cell expressing a peptide antigen on its cell surface in association with an MHC protein complex.
39589	suppression by virus of host TAP complex	P	Any process in which a virus stops, prevents, or reduces the activity of the host TAP complex, a heterodimer composed of the subunits TAP1 and TAP2 (transporter associated with antigen presentation). The TAP complex functions in the transport of antigenic peptides from the cytosol to the lumen of the endoplasmic reticulum, where they are loaded onto the MHC class I. By inhibiting the TAP complex, the virus prevents viral particles being presented at the cell surface, and thus evades the host immune response.
39591	suppression by virus of host tapasin activity	P	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host tapasin (TAP binding protein/TAPBP) activity. Tapasin is a type I transmembrane protein essential for the optimal expression of stable MHC class I molecules on the host cell surface. By inhibiting host tapasin activity, viruses can prevent presentation of their antigens at the cell surface, and thereby evade the host anti-viral immune response.
39592	suppression by virus of G2/M transition of host mitotic cell cycle	P	Any viral process that decreases the rate or extent of progression from G2 phase to M phase of the host mitotic cell cycle.
39593	suppression by virus of host exit from mitosis	P	Any viral process which decreases the rate or extent of a host cell leaving M phase of the cell cycle. M phase is the part of the mitotic cell cycle during which mitosis and cytokinesis take place.
39594	endoribonuclease activity involved in viral induction of host mRNA catabolic process	F	Any endoribonuclease activity that contributes to the viral-induced catabolism of host mRNA.
39595	induction by virus of catabolism of host mRNA	P	The process in which a virus increases the frequency, rate or extent of the breakdown of host messenger RNA (mRNA).
39596	modulation by virus of host protein dephosphorylation	P	Any viral process that modulates the frequency, rate or extent of dephosphorylation of a host protein.
39597	induction by virus of host endoribonuclease activity	P	Any viral process that activates or increases the frequency, rate or extent of host endoribonuclease activity.
39599	cleavage by virus of host mRNA	P	Any process in which a host pre-mRNA or mRNA molecule is cleaved at specific sites or in a regulated manner by a viral endoribonuclease.
39600	induction by virus of host endonucleolytic cleavage-dependent mRNA catabolic process	P	The process in which a virus increases the frequency, rate or extent of the breakdown of host nuclear-transcribed mRNAs that begins with endonucleolytic cleavage (by either a host or a viral RNAse) to generate unprotected ends.
39602	suppression by virus of host transcription initiation from RNA polymerase II promoter	P	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of the assembly of the RNA polymerase II preinitiation complex (PIC) at an RNA polymerase II promoter region of a host DNA template.
39603	TBP-class protein binding involved in viral suppression of host transcription initiation from RNA polymerase II promoter	F	Selective and non-covalent interaction of a viral protein with a member of the class of TATA-binding proteins (TBP) in the host, including any of the TBP-related factors (TRFs), which contributes to the viral-suppression of assembly of the RNA polymerase II preinitiation complex (PIC) at an RNA polymerase II promoter region of a host DNA template.
39604	suppression by virus of host translation	P	Any process in which a virus prevents or reduces the frequency, rate or extent of translation of host mRNA.
39605	TFIIB-class transcription factor binding involved in viral suppression of host transcription initiation from RNA polymerase II promoter	F	Selective and non-covalent interaction of a viral protein with a member of the TFIIB-class of host transcription factors, which contributes to the viral-suppression of assembly of the RNA polymerase II preinitiation complex (PIC) at an RNA polymerase II promoter region of a host DNA template.
39606	suppression by virus of host translation initiation	P	Any process in which a virus prevents or reduces the frequency, rate or extent of host translation initiation, the host process preceding formation of the peptide bond between the first two amino acids of a protein.
39607	proteolysis by virus of host translation initiation factor	P	The chemical reactions and pathways performed by a virus resulting in the hydrolysis of a host translation initiation factor by cleavage of its peptide bonds.
39608	suppression by virus of host translation initiation factor activity by induction of host protein dephosphorylation	P	Any process in which a virus prevents or reduces the frequency, rate or extent of activity of a host translation initiation factor by promoting dephosphorylation of a host protein.
39611	suppression by virus of host translation initiation factor activity	P	Any process in which a virus prevents or reduces the frequency, rate or extent of activity of a host translation initiation factor.
39612	modulation by virus of host protein phosphorylation	P	Any viral process that modulates the frequency, rate or extent of phosphorylation of viral or host proteins in a host.
39613	suppression by virus of host protein phosphorylation	P	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of phosphorylation of viral or host proteins in a host.
39614	induction by virus of host protein phosphorylation	P	Any process in which a virus activates or increases the frequency, rate or extent of phosphorylation of viral or host proteins in a host.
39615	T=1 icosahedral viral capsid	C	The protein coat that surrounds the infective nucleic acid in some virus particles where the subunits (capsomeres) are arranged to form an icosahedron with T=1 symmetry. The T=1 capsid is composed of 12 pentameric capsomeres.
39616	T=2 icosahedral viral capsid	C	The protein coat that surrounds the infective nucleic acid in some virus particles where the subunits (capsomeres) are arranged to form an icosahedron with T=2 symmetry. The T=2 capsid is composed of 12 pentameric dimers.
39617	T=3 icosahedral viral capsid	C	The protein coat that surrounds the infective nucleic acid in some virus particles where the subunits (capsomeres) are arranged to form an icosahedron with T=3 symmetry. The T=3 capsid is composed of 12 pentameric and 20 hexameric capsomeres.
39618	T=pseudo3 icosahedral viral capsid	C	The protein coat that surrounds the infective nucleic acid in some virus particles where the subunits (capsomeres) are arranged to form an icosahedron with pseudo T=3 symmetry. The T=pseudo3 capsid is composed of 12 pentameric and 20 hexameric capsomeres.
39619	T=4 icosahedral viral capsid	C	The protein coat that surrounds the infective nucleic acid in some virus particles where the subunits (capsomeres) are arranged to form an icosahedron with T=4 symmetry. The T=4 capsid is composed of 12 pentameric and 30 hexameric capsomeres.
39620	T=7 icosahedral viral capsid	C	The protein coat that surrounds the infective nucleic acid in some virus particles where the subunits (capsomeres) are arranged to form an icosahedron with T=7 symmetry. The T=7 capsid is composed of 12 pentameric and 60 hexameric capsomeres.
39621	T=13 icosahedral viral capsid	C	The protein coat that surrounds the infective nucleic acid in some virus particles where the subunits (capsomeres) are arranged to form an icosahedron with T=13 symmetry. The T=13 capsid is composed of 12 pentameric and 120 hexameric capsomeres.
39622	T=16 icosahedral viral capsid	C	The protein coat that surrounds the infective nucleic acid in some virus particles where the subunits (capsomeres) are arranged to form an icosahedron with T=16 symmetry. The T=16 capsid is composed of 12 pentameric and 150 hexameric capsomeres.
39623	T=25 icosahedral viral capsid	C	The protein coat that surrounds the infective nucleic acid in some virus particles where the subunits (capsomeres) are arranged to form an icosahedron with T=25 symmetry. The T=25 capsid is composed of 12 pentameric and 240 hexameric capsomeres.
39624	viral outer capsid	C	The outer layer of a double or triple concentric icosahedral capsid. Outer capsids are part of reoviridae and cystoviridae virions.
39625	viral inner capsid	C	The inner layer of a double or triple concentric icosahedral capsid. Inner capsids are part of reoviridae and cystoviridae virions.
39626	viral intermediate capsid	C	The intermediate layer of a triple concentric icosahedral capsid. Intermediate capsids are part of reoviridae virions.
39627	T=147 icosahedral capsid	C	The protein coat that surrounds the infective nucleic acid in some virus particles where the subunits (capsomeres) are arranged to form an icosahedron with T=147 symmetry. T=147 icosahedral capsid is composed of 12 pentameric and 1460 hexameric capsomeres for a total of 8820 capsid proteins.
39628	T=169 icosahedral viral capsid	C	The protein coat that surrounds the infective nucleic acid in some virus particles where the subunits (capsomeres) are arranged to form an icosahedron with T=169 symmetry. T=169 icosahedral capsid is composed of 12 pentameric and 1680 hexameric capsomeres for a total of 10140 capsid proteins.
39629	T=219 icosahedral capsid	C	The protein coat that surrounds the infective nucleic acid in some virus particles where the subunits (capsomeres) are arranged to form an icosahedron with T=219 symmetry. T=219 icosahedral capsid is composed of 12 pentameric and 2180 hexameric capsomeres for a total of 13140 capsid proteins.
39630	RNA translocase activity	F	Catalysis of the reaction: ATP + H2O = ADP + phosphate, to drive movement along a single- or double-stranded RNA molecule.
39631	DNA translocase activity involved in viral DNA genome packaging	F	Catalysis of the reaction: ATP + H2O = ADP + phosphate, to drive movement along a single- or double-stranded DNA molecule, that contributes to the packing of viral DNA into a capsid.
39632	RNA translocase activity involved in viral RNA genome packaging	F	Catalysis of the reaction: ATP + H2O = ADP + phosphate, to drive movement along a single- or double-stranded RNA molecule, which contributes to the packaging of viral RNA into a nucleocapsid.
39633	killing by virus of host cell	P	Any process mediated by a virus that results in the death of a cell in the host organism.
39634	killing by virus of host cell during superinfection exclusion	P	The viral-killing of a host cell by a pre-existing virus in response to a subsequent infection of the host cell by second virus.
39635	suppression by virus of host peptidoglycan biosynthetic process	P	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of peptidoglycan biosynthesis in the host organism. Peptidoglycans are any of a class of glycoconjugates found in bacterial cell walls.
39636	suppression by virus of host cell wall biogenesis	P	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of cell wall biogenesis in the host organism. Cell wall biogenesis includes the biosynthesis of constituent macromolecules, and the assembly and arrangement of these constituent parts.
39637	catabolism by virus of host DNA	P	The breakdown of host DNA, deoxyribonucleic acid, by a virus.
39638	lipopolysaccharide-mediated virion attachment to host cell	P	The process by which a virion attaches to a host cell by binding to a lipopolysaccharide (LPS) on the host cell surface.
39639	suppression by virus of host cell lysis in response to superinfection	P	The prevention or delay of host cell lysis by a pre-existing virus in response to a subsequent infection of the host cell by second virus.
39640	cytolysis by virus via suppression of host peptidoglycan biosynthetic process	P	The killing by a virus of host cell by cytolysis, caused by a virus stopping, preventing, or reducing peptidoglycan biosynthesis in the host organism. Peptidoglycans are any of a class of glycoconjugates found in bacterial cell walls.
39641	viral inner membrane	C	The lipid bilayer of a virion contained inside the protein capsid.
39642	virion nucleoid	C	The region of a virion in which the nucleic acid is confined.
39643	host cell viral nucleoid	C	The region of a host cell that contains the viral genome.
39644	suppression by virus of host NF-kappaB transcription factor activity	P	Any process in which a virus stops, prevents, or reduces the activity of host NF-kappaB activity.
39645	modulation by virus of host G1/S transition checkpoint	P	Any viral process that modulates the frequency, rate or extent of the host cell G1/S transition checkpoint.
39646	modulation by virus of host G0/G1 transition checkpoint	P	Any viral process that modulates the frequency, rate or extent of the host cell G0/G1 transition checkpoint.
39647	suppression by virus of host poly(A)-binding protein activity	P	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host poly(A)-binding protein (PABP) activity. PABP binds to the poly(A) tail of mRNA to facilitate translation.
39648	modulation by virus of host protein ubiquitination	P	Any process in which a virus modulates the frequency, rate or extent of protein ubiquitination in the host organism. Ubiquitination is the process in which one or more ubiquitin groups are added to a protein.
39649	modulation by virus of host ubiquitin-protein ligase activity	P	The process in which a virus effects a change in host ubiquitin-protein ligase activity. Ubiquitin-protein ligase activity catalyzes the reaction: ATP + ubiquitin + protein lysine = AMP + diphosphate + protein N-ubiquityllysine.
39650	suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process	P	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of host caspase activity. Caspases are cysteine-type endopeptidases which contribute to the apoptotic process.
39651	induction by virus of host cysteine-type endopeptidase activity involved in apoptotic process	P	Any process in which a virus increases the frequency, rate or extent of host cysteine-type endopeptidase activity (also called caspase activity) which contributes to the apoptotic process.
39652	activation by virus of host NF-kappaB transcription factor activity	P	Any process in which a virus starts, promotes, or enhances the activity of the host transcription factor NF-kappaB.
39653	suppression by virus of host transcription	P	Any process in which a virus stops, prevents, or reduces the activity of host DNA-dependent transcription; the cellular synthesis of RNA on a template of DNA. Viral proteins can interfere with either host RNA polymerase or with transcription factors.
39654	fusion of virus membrane with host endosome membrane	P	Fusion of a virus membrane with a host endosome membrane. Occurs after internalization of the virus through the endosomal pathway, and results in release of the virus contents into the cell.
39655	transport of virus in host, cell to cell via plasmodesmata	P	The transport of a virus between adjacent cells in a multicellular organism using plasmodesmata. Plasmodesma is a fine cytoplasmic channel found in all higher plants, which connects the cytoplasm of one cell to that of an adjacent cell.
39656	modulation by virus of host gene expression	P	The process in which a virus effects a change in gene expression in its host organism. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Some protein processing events may be included when they are required to form an active form of a product from an inactive precursor form.
39657	suppression by virus of host gene expression	P	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of gene expression in the host organism. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Some protein processing events may be included when they are required to form an active form of a product from an inactive precursor form.
39658	TBK1-IKKE-DDX3 complex	C	A protein complex containing TBK1 (TANK-binding kinase 1), IKBKE (I-Kappa-B kinase epsilon/IKKE/IKK-epsilon) and the DEAD box family RNA helicase DDX3.
39659	suppression by virus of host TBK1-IKBKE-DDX3 complex activity	P	Any process in which a virus stops, prevents, or reduces the activity of the host TBK1-IKBKE-DDX3 complex.
39660	structural constituent of virion	F	The action of a molecule that contributes to the structural integrity of a virion.
39661	host organelle outer membrane	C	The outer, i.e. cytoplasm-facing in a cellular organelle, lipid bilayer of an organelle envelope, occurring in a host cell.
39662	host cell outer membrane	C	A lipid bilayer that forms the outermost layer of the cell envelope, occurring in a host cell.
39663	membrane fusion involved in viral entry into host cell	P	Merging of the virion membrane and a host membrane (host plasma membrane or host organelle membrane) that is involved in the uptake of a virus into a host cell.
39664	lysis of host organelle involved in viral entry into host cell	P	The viral-induced lysis of an organelle (endosome, lysosome, or caveosome) that is involved in the uptake of a virus into a host cell. Occurs once the virus is within the organelle, and results in transfer of the viral contents from the organelle compartment into the cytoplasm.
39665	permeabilization of host organelle membrane involved in viral entry into host cell	P	Induction of organellar membrane permeabilization triggered by an interaction between the host membrane and a membrane-penetration protein associated with a viral capsid. Results in release of the virus contents from an organelle into the host cell cytoplasm.
39666	virion attachment to host cell pilus	P	The process by which a virion attaches to a host cell by binding to a pilus on the host cell surface. Pili are retractile filaments that protrude from gram-negative bacteria. Filamentous viruses can attach to the pilus tip, whereas icosahedral viruses can attach to the pilus side.
39667	viral entry into host cell via pilus retraction	P	The uptake of a virus or viral genetic material into a host cell which occurs through retraction of a virion-bound pilus.
39668	viral entry into host cell via pilus basal pore	P	The uptake of a virus or viral genetic material into a host cell which occurs through retraction of the virion-bound pilus, followed by entry of the viral genome into the host cell through the pilus basal pore. Filamentous bacteriophages absorb to the tip of the F-pili and can enter the bacterial cell in this way.
39669	viral entry into host cell via pilus retraction and membrane fusion	P	The uptake of a virus into a host cell which occurs via retraction of the viral-bound pilus to bring the virus in contact with the host cell membrane, followed by fusion of the bacteriophage membrane with the host outer membrane.
39670	viral capsid, turret	C	A turret-like appendage formed at the vertices of an icosahedral capsid.
39671	evasion by virus of host natural killer cell activity	P	Any process by which a virus avoids the effects mediated by the host organism's natural killer (NK) cells.
39672	suppression by virus of host natural killer cell activation	P	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of natural killer cell activation in the host.
39673	evasion by virus of host dendritic cell activity	P	Any process by which a virus avoids the effects mediated by the host organism's dendritic cells.
39674	exit of virus from host cell nucleus	P	The directed movement of the viral genome or a viral particle out of the host cell nucleus.
39675	exit of virus from host cell nucleus through nuclear pore	P	The directed movement of the viral genome or a viral particle out of the host cell nucleus through the nuclear pore.
39677	exit of virus from host cell nucleus via nuclear envelope disassembly	P	The directed movement of the viral genome or a viral particle out of the host cell nucleus that involves disruption of the nuclear membrane envelope by the virus.
39678	viral genome ejection through host cell envelope	P	Ejection by a non-enveloped prokaryotic virus of its genome into the host cytoplasm. Caudovirales carry an ejection apparatus that can be long and contractile, long and noncontractile, or short, and is able to penetrate the host cell envelope to deliver the viral genome into the host cell cytoplasm.
39679	viral occlusion body	C	A crystalline protein matrix surrounding the nucleocapsids of some insect viruses after their release in the environment. Produced in the host cell, the occlusion body protects the infectious virion after death of the host.
39680	actin-dependent intracellular transport of virus towards nucleus	P	The directed movement of a virus, or part of a virus, towards the host cell nucleus using actin filaments.
39682	rolling circle viral DNA replication	P	A process of unidirectional viral DNA replication that takes place on a circular DNA to rapidly produce numerous copies of the viral genome. Involves creating a nick in one strand of the circular DNA molecule at the origin of replication. DNA is then synthesized by DNA polymerase. Using the non-nicked strand as a template, replication proceeds around the circular DNA molecule, displacing the nicked strand as single-stranded DNA.
39683	rolling circle double-stranded viral DNA replication	P	A rolling circle viral DNA replication that begins with a double-stranded viral DNA genome.
39684	rolling circle single-stranded viral DNA replication	P	A rolling circle viral DNA replication that begins with a single-stranded viral DNA genome.
39685	rolling hairpin viral DNA replication	P	A viral DNA replication process where a 3' hairpin structure in the viral single-stranded DNA (ssDNA) template serves as a primer for host enzymes to synthesize DNA.
39686	bidirectional double-stranded viral DNA replication	P	A viral DNA replication process where replication occurs in both directions from the starting point. This creates two replication forks, moving in opposite directions.
39687	viral DNA strand displacement replication	P	A viral DNA replication process where only one strand is replicated at once, and which releases a single stranded DNA (ssDNA).
39688	viral double stranded DNA replication via reverse transcription	P	A DNA replication process that uses viral RNA as a template for RNA-dependent DNA polymerases (e.g. reverse transcriptase) that synthesize the new strands.
39689	negative stranded viral RNA replication	P	A viral genome replication process where the template genome is negative stranded, single stranded RNA ((-)ssRNA).
39690	positive stranded viral RNA replication	P	A viral genome replication process where the template genome is positive stranded, single stranded RNA ((+)ssRNA). Replication of the positive strand leads to dsRNA formation, which in turn is transcribed into positive single stranded RNA.
39691	double stranded viral RNA replication	P	A viral genome replication process where the template genome is double stranded RNA (dsRNA). Genomic dsRNA is first transcribed into single-stranded (ss) mRNA, which is then replicated to ds-genomic RNA.
39692	single stranded viral RNA replication via double stranded DNA intermediate	P	A viral genome replication where the template is single-stranded RNA (ssRNA), and which proceeds via a double stranded DNA (dsDNA) intermediate molecule. Viral genomic RNA is first reverse transcribed into dsDNA, which integrates into the host chromosomal DNA, where it is transcribed by host RNA polymerase II.
39693	viral DNA genome replication	P	The replication of a viral DNA genome.
39694	viral RNA genome replication	P	The replication of a viral RNA genome.
39695	DNA-templated viral transcription	P	A transcription process that uses a viral DNA as a template.
39696	RNA-templated viral transcription	P	A transcription process that uses viral RNA as a template.
39697	negative stranded viral RNA transcription	P	A viral transcription process that uses negative stranded (-) single stranded (ss) RNA as a template.
39698	polyadenylation of viral mRNA by polymerase stuttering	P	Polyadenylation of viral mRNA through a polymerase stuttering mechanism. The stop signal present at the end of each gene comprises a stretch of uridine on which the viral polymerase acquires a stuttering behavior: after each adenine inserted, the polymerase moves back one nucleotide along with the mRNA. It resumes transcription adding a new adenine, then again moves back, thereby producing a polyA tail.
39699	viral mRNA cap methylation	P	Methylation of the 2'-O-ribose of the first or second transcribed nucleotide of a viral mRNA. Methylation allows evasion of the host innate immune response, which degrades cap0 (non-methylated) mRNAs.
39700	fusion of viral membrane with host outer nuclear membrane	P	Fusion of a viral primary envelope with the host outer nuclear membrane during nuclear egress. The transitory primary envelope is acquired by the virus as it buds at the inner nuclear membrane and gains access to the perinuclear space. This membrane is lost by fusing with the host outer nuclear membrane during nuclear exit.
39701	microtubule-dependent intracellular transport of viral material towards cell periphery	P	The directed movement of the viral genome or a viral particle towards the cell periphery using host microtubules. Mostly used by viruses that replicate their genome near or in the nucleus to allows newly assembled viral progeny to reach the plasma membrane.
39702	viral budding via host ESCRT complex	P	Viral budding which uses a host ESCRT protein complex, or complexes, to mediate the budding process.
39703	RNA replication	P	The cellular metabolic process in which a cell duplicates one or more molecules of RNA.
39704	viral translational shunt	P	A viral translation initiation mechanism where ribosomes are loaded onto viral mRNA at the 5'-cap structure and start scanning for a short distance before by-passing the large internal leader region and initiating at a downstream start site.
39705	viral translational readthrough	P	The continuation of translation of a viral mRNA beyond a stop codon by the use of a special tRNA that recognizes the UAG and UGA codons as modified amino acids, rather than as termination codons.
39706	co-receptor binding	F	Interacting selectively and non-covalently with a coreceptor. A coreceptor acts in cooperation with a primary receptor to transmit a signal within the cell.
39707	pore formation by virus in membrane of host cell	P	The aggregation, arrangement and bonding together of a set of components by a virus to form a pore complex in a membrane of a host organism.
39708	nuclear capsid assembly	P	The assembly of a virus capsid that occurs in the nucleus. The assembly of large icosahedral shells for herpesviridae and adenoviridae requires structural proteins that act as chaperones for assembly.
39709	cytoplasmic capsid assembly	P	The assembly of a virus capsid that occurs in the cytoplasm.
39710	cytoplasmic icosahedral capsid assembly	P	The assembly of an icosahedral viral capsid in the cytoplasm. Often occurs by assembling around the viral genome.
39711	cytoplasmic helical capsid assembly	P	The assembly of a helical viral capsid in the cytoplasm. Occurs by assembling around the viral genome.
39712	induction by virus of host catalytic activity	P	Any viral process that activates or increases the frequency, rate or extent of host catalytic activity.
39713	viral factory	C	An intracellular compartment in a host cell which increases the efficiency of viral replication and/or assembly, and shields the virus from host defenses. Viral factories can be either cytoplasmic or nuclear and often arise from extensive rearrangement of host cell cytoskeletal and/or cell membrane compartments.
39714	cytoplasmic viral factory	C	A viral factory located in the cytoplasm of a host cell.
39715	nuclear viral factory	C	A viral factory located in the nucleus of a host cell.
39716	viroplasm viral factory	C	A cytoplasmic viral factory that is electron dense due to high levels of viral RNA. Produced by nucleo-cytoplasmic large DNA viruses (NCLDV) like Poxviridae, Asfarviridae and Iridoviridae, and dsRNA viruses like Reoviridae.
39717	spherule viral factory	C	A cytoplasmic viral factory which is a 50-400nm diameter membrane invagination. Spherules can appear on several enveloped cellular components depending on the virus.
39718	double membrane vesicle viral factory	C	A cytoplasmic viral factory that consists of a double-membrane bound vesicle. Has a diameter of 200-300nm and is derived from the endoplasmic reticulum or Golgi apparatus. Produced by Picornaviridae, Nidovirales, Arteriviridae and Coronaviridae.
39719	tube viral factory	C	A cytoplasmic viral factory derived from the Golgi in which Bunyaviridae replication takes place. Tubes are membranous structures close to the assembly and budding sites, and their function may be to connect viral replication and morphogenesis inside viral factories.
39720	virogenic stroma	C	A nuclear viral factory formed by Baculoviruses. A vesicular structure in which virions are assembled.
39721	peristromal region viral factory	C	A nuclear viral factory formed at the periphery of the host cell nucleus by Baculoviruses.
39722	suppression by virus of host toll-like receptor signaling pathway	P	Any process in which a virus stops, prevents, or reduces the frequency, rate or extent of toll-like receptor (TLR) signaling in the host organism.
39723	suppression by virus of host TBK1 activity	P	Any process in which a virus stops, prevents, or reduces the activity of the host serine/threonine kinase TBK1.
39724	suppression by virus of host IKBKE activity	P	Any process in which a virus stops, prevents, or reduces the activity of the host I-kappa-B kinase epsilon (IKBKE/IKK-epsilon/IKK-E).
40001	establishment of mitotic spindle localization	P	The cell cycle process in which the directed movement of the mitotic spindle to a specific location in the cell occurs.
40002	collagen and cuticulin-based cuticle development	P	Synthesis and deposition of a collagen and cuticulin-based noncellular, hardened, or membranous secretion from an epithelial sheet. An example of this process is found in Caenorhabditis elegans.
40003	chitin-based cuticle development	P	Synthesis and deposition of a chitin-based noncellular, hardened, or membranous secretion from an epithelial sheet. An example of this process is found in Drosophila melanogaster.
40004	collagen and cuticulin-based cuticle attachment to epithelium	P	Attaching of a collagen and cuticulin-based cuticle to the epithelium underlying it. An example of this process is found in Caenorhabditis elegans.
40005	chitin-based cuticle attachment to epithelium	P	Attaching of a chitin-containing cuticle to the epithelium underlying it. An example of this process is found in Drosophila melanogaster.
40007	growth	P	The increase in size or mass of an entire organism, a part of an organism or a cell.
40008	regulation of growth	P	Any process that modulates the frequency, rate or extent of the growth of all or part of an organism so that it occurs at its proper speed, either globally or in a specific part of the organism's development.
40009	regulation of growth rate	P	Any process that modulates the rate of growth of all or part of an organism.
40010	positive regulation of growth rate	P	Any process that increases the rate of growth of all or part of an organism.
40011	locomotion	P	Self-propelled movement of a cell or organism from one location to another.
40012	regulation of locomotion	P	Any process that modulates the frequency, rate or extent of locomotion of a cell or organism.
40013	negative regulation of locomotion	P	Any process that stops, prevents, or reduces the frequency, rate or extent of locomotion of a cell or organism.
40014	regulation of multicellular organism growth	P	Any process that modulates the frequency, rate or extent of growth of the body of an organism so that it reaches its usual body size.
40015	negative regulation of multicellular organism growth	P	Any process that stops, prevents, or reduces the frequency, rate or extent of growth of an organism to reach its usual body size.
40016	embryonic cleavage	P	The first few specialized divisions of an activated animal egg.
40017	positive regulation of locomotion	P	Any process that activates or increases the frequency, rate or extent of locomotion of a cell or organism.
40018	positive regulation of multicellular organism growth	P	Any process that activates or increases the frequency, rate or extent of growth of an organism to reach its usual body size.
40019	positive regulation of embryonic development	P	Any process that activates or increases the frequency, rate or extent of embryonic development.
40020	regulation of meiotic nuclear division	P	Any process that modulates the frequency, rate or extent of meiosis, the process in which the nucleus of a diploid cell divides twice forming four haploid cells, one or more of which usually function as gametes.
40021	hermaphrodite germ-line sex determination	P	The determination of sex and sexual phenotype in the germ line of a hermaphrodite.
40022	feminization of hermaphroditic germ-line	P	The determination of female sex and sexual phenotype in the germ-line of the hermaphrodite.
40023	establishment of nucleus localization	P	The directed movement of the nucleus to a specific location within a cell.
40024	dauer larval development	P	The process whose specific outcome is the progression of the dauer larva over time, through the facultative diapause of the dauer (enduring) larval stage, with specialized traits adapted for dispersal and long-term survival, with elevated stress resistance and without feeding.
40025	vulval development	P	The process whose specific outcome is the progression of the egg-laying organ of female and hermaphrodite nematodes over time, from its formation to the mature structure. In nematodes, the vulva is formed from ventral epidermal cells during larval stages to give rise to a fully formed vulva in the adult.
40026	positive regulation of vulval development	P	Any process that activates or increases the frequency, rate or extent of development of the vulva. Vulval development is the process whose specific outcome is the progression of the egg-laying organ of female and hermaphrodite nematodes over time, from its formation to the mature structure. In nematodes, the vulva is formed from ventral epidermal cells during larval stages to give rise to a fully formed vulva in the adult.
40027	negative regulation of vulval development	P	Any process that stops, prevents, or reduces the frequency, rate or extent of development of the vulva. Vulval development is the process whose specific outcome is the progression of the egg-laying organ of female and hermaphrodite nematodes over time, from its formation to the mature structure. In nematodes, the vulva is formed from ventral epidermal cells during larval stages to give rise to a fully formed vulva in the adult.
40028	regulation of vulval development	P	Any process that modulates the frequency, rate or extent of development of the vulva. Vulval development is the process whose specific outcome is the progression of the egg-laying organ of female and hermaphrodite nematodes over time, from its formation to the mature structure. In nematodes, the vulva is formed from ventral epidermal cells during larval stages to give rise to a fully formed vulva in the adult.
40029	regulation of gene expression, epigenetic	P	Any process that modulates the frequency, rate or extent of gene expression; the process is mitotically or meiotically heritable, or is stably self-propagated in the cytoplasm of a resting cell, and does not entail a change in DNA sequence.
40030	regulation of molecular function, epigenetic	P	Any heritable epigenetic process that modulates the frequency, rate or extent of protein function by self-perpetuating conformational conversions of normal proteins in healthy cells. This is distinct from, though mechanistically analogous to, disease states associated with prion propagation and amyloidogenesis. A single protein, if it carries a glutamine/asparagine-rich ('prion') domain, can sometimes stably exist in at least two distinct physical states, each associated with a different phenotype; propagation of one of these traits is achieved by a self-perpetuating change in the protein from one form to the other, mediated by conformational changes in the glutamine/asparagine-rich domain. Prion domains are both modular and transferable to other proteins, on which they can confer a heritable epigenetic alteration of function; existing bioinformatics data indicate that they are rare in non-eukarya, but common in eukarya.
40031	snRNA modification	P	The covalent alteration of one or more nucleotides within snRNA, resulting in a change in the properties of the snRNA.
40032	post-embryonic body morphogenesis	P	The process in which the anatomical structures of the post-embryonic soma are generated and organized.
40033	negative regulation of translation, ncRNA-mediated	P	Any process, mediated by small non-coding RNAs, that stops, prevents or reduces the rate that mRNAs are effectively translated into protein.
40034	regulation of development, heterochronic	P	Any process that modulates the consistent predetermined time point at which an integrated living unit or organism progresses from an initial condition to a later condition and the rate at which this time point is reached.
40035	hermaphrodite genitalia development	P	The process whose specific outcome is the progression of the hermaphrodite genitalia over time, from formation to the mature structures.
40036	regulation of fibroblast growth factor receptor signaling pathway	P	Any process that modulates the frequency, rate or extent of fibroblast growth factor receptor signaling pathway activity.
40037	negative regulation of fibroblast growth factor receptor signaling pathway	P	Any process that stops, prevents, or reduces the frequency, rate or extent of fibroblast growth factor receptor signaling pathway activity.
40038	polar body extrusion after meiotic divisions	P	The cell cycle process in which two small cells are generated, as byproducts destined to degenerate, as a result of the first and second meiotic divisions of a primary oocyte during its development to a mature ovum. One polar body is formed in the first division of meiosis and the other in the second division; at each division, the cytoplasm divides unequally, so that the polar body is of much smaller size than the developing oocyte. At the second division in which a polar body is formed, the polar body and the developing oocyte each contain a haploid set of chromosomes.
40039	inductive cell migration	P	Migration of a cell in a multicellular organism that, having changed its location, is required to induce normal properties in one or more cells at its new location. An example of this would be the distal tip cells of Caenorhabditis elegans.
40040	thermosensory behavior	P	Behavior that is dependent upon the sensation of temperature.
42000	translocation of peptides or proteins into host	P	The directed movement of peptides or proteins produced by an organism to a location inside its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
42001	hermaphrodite somatic sex determination	P	The determination of sex and sexual phenotypes in a hermaphroditic organism's soma. An example of this is found in Caenorhabditis elegans.
42003	masculinization of hermaphrodite soma	P	Promotion of male sex and sexual phenotypes in the hermaphroditic nematode soma. An example of this is found in Caenorhabditis elegans.
42004	feminization of hermaphrodite soma	P	Promotion of female sex and sexual phenotypes in the hermaphroditic soma. An example of this is found in Caenorhabditis elegans.
42006	masculinization of hermaphroditic germ-line	P	The determination of male sex and sexual phenotype in the germ-line of the hermaphrodite. An example of this is found in Caenorhabditis elegans.
42007	interleukin-18 binding	F	Interacting selectively and non-covalently with interleukin-18.
42008	interleukin-18 receptor activity	F	Combining with interleukin-18 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
42009	interleukin-15 binding	F	Interacting selectively and non-covalently with interleukin-15.
42010	interleukin-15 receptor activity	F	Combining with interleukin-15 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
42011	interleukin-16 binding	F	Interacting selectively and non-covalently with interleukin-16.
42012	interleukin-16 receptor activity	F	Combining with interleukin-16 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
42013	interleukin-19 binding	F	Interacting selectively and non-covalently with interleukin-19.
42014	interleukin-19 receptor activity	F	Combining with interleukin-19 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
42015	interleukin-20 binding	F	Interacting selectively and non-covalently with interleukin-20.
42016	interleukin-20 receptor activity	F	Combining with interleukin-20 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
42017	interleukin-22 binding	F	Interacting selectively and non-covalently with interleukin-22.
42018	interleukin-22 receptor activity	F	Combining with interleukin-22 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
42019	interleukin-23 binding	F	Interacting selectively and non-covalently with interleukin-23.
42020	interleukin-23 receptor activity	F	Combining with interleukin-23 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
42021	granulocyte macrophage colony-stimulating factor complex binding	F	Interacting selectively and non-covalently with the granulocyte macrophage colony-stimulating factor complex.
42022	interleukin-12 receptor complex	C	A protein complex that binds interleukin-12 and that consists of, at a minimum, a dimeric interleukin and its two receptor subunits as well as optional additional kinase subunits.
42023	DNA endoreduplication	P	Regulated re-replication of DNA within a single cell cycle, resulting in an increased cell ploidy. An example of this process occurs in the synthesis of Drosophila salivary gland cell polytene chromosomes.
42025	host cell nucleus	C	A membrane-bounded organelle as it is found in the host cell in which chromosomes are housed and replicated. The host is defined as the larger of the organisms involved in a symbiotic interaction.
42026	protein refolding	P	The process carried out by a cell that restores the biological activity of an unfolded or misfolded protein, using helper proteins such as chaperones.
42030	ATPase inhibitor activity	F	Stops, prevents or reduces the activity of any enzyme that catalyzes the hydrolysis of ATP to ADP and orthophosphate.
42033	chemokine biosynthetic process	P	The chemical reactions and pathways resulting in the formation of chemokines, any member of a family of small chemotactic cytokines; their name is derived from their ability to induce directed chemotaxis in nearby responsive cells. All chemokines possess a number of conserved cysteine residues involved in intramolecular disulfide bond formation. Some chemokines are considered pro-inflammatory and can be induced during an immune response to recruit cells of the immune system to a site of infection, while others are considered homeostatic and are involved in controlling the migration of cells during normal processes of tissue maintenance or development. Chemokines are found in all vertebrates, some viruses and some bacteria.
42034	peptidyl-L-lysine methyl ester biosynthetic process from peptidyl-lysine	P	The modification of a C-terminal peptidyl-lysine to form peptidyl-L-lysine methyl ester.
42035	regulation of cytokine biosynthetic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cytokines.
42036	negative regulation of cytokine biosynthetic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cytokines.
42037	peptidyl-histidine methylation, to form pros-methylhistidine	P	The methylation of peptidyl-L-histidine to form peptidyl-L-3'-methyl-L-histidine (otherwise known as pi-methylhistidine, pros-methylhistidine).
42038	peptidyl-histidine methylation, to form tele-methylhistidine	P	The methylation of peptidyl-L-histidine to form peptidyl-L-1'-methyl-L-histidine (otherwise known as tau-methylhistidine, tele-methylhistidine).
42039	vanadium incorporation into metallo-sulfur cluster	P	The incorporation of vanadium a metallo-sulfur cluster such as VFe(7-8)S(n).
42040	metal incorporation into metallo-molybdopterin complex	P	The incorporation of a metal into a metallo-molybdopterin complex.
42042	tungsten incorporation into tungsten-molybdopterin complex	P	The incorporation of tungsten into a tungsten-molybdopterin complex.
42043	neurexin family protein binding	F	Interacting selectively and non-covalently with neurexins, synaptic cell surface proteins related to latrotoxin receptor, laminin and agrin. Neurexins act as cell recognition molecules at nerve terminals.
42044	fluid transport	P	The directed movement of substances that are in liquid form in normal living conditions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
42045	epithelial fluid transport	P	The directed movement of fluid across epithelia.
42046	W-molybdopterin cofactor metabolic process	P	The chemical reactions and pathways involving the W-molybdopterin cofactor, essential for the catalytic activity of some enzymes. The cofactor consists of a mononuclear tungsten ion (W) coordinated by one or two molybdopterin ligands.
42047	W-molybdopterin cofactor biosynthetic process	P	The chemical reactions and pathways resulting in the formation of the W-molybdopterin cofactor, essential for the catalytic activity of some enzymes. The cofactor consists of a mononuclear tungsten ion (W) coordinated by one or two molybdopterin ligands.
42048	olfactory behavior	P	The behavior of an organism in response to an odor.
42049	cellular acyl-CoA homeostasis	P	Any process involved in the maintenance of an internal steady state of acyl-CoA within a cell or between a cell and its external environment.
42051	compound eye photoreceptor development	P	The process whose specific outcome is the progression of a light-responsive receptor in the compound eye over time, from its formation to the mature structure.
42052	rhabdomere development	P	The assembly and arrangement of a rhabdomere within a cell. The rhabdomere is the organelle on the apical surface of a photoreceptor cell that contains the visual pigments.
42053	regulation of dopamine metabolic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving dopamine.
42054	histone methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + histone = S-adenosyl-L-homocysteine + methyl-histone. Histone methylation generally occurs on either an arginine or lysine residue.
42056	chemoattractant activity	F	Providing the environmental signal that initiates the directed movement of a motile cell or organism towards a higher concentration of that signal.
42058	regulation of epidermal growth factor receptor signaling pathway	P	Any process that modulates the frequency, rate or extent of epidermal growth factor receptor signaling pathway activity.
42059	negative regulation of epidermal growth factor receptor signaling pathway	P	Any process that stops, prevents, or reduces the frequency, rate or extent of epidermal growth factor receptor signaling pathway activity.
42060	wound healing	P	The series of events that restore integrity to a damaged tissue, following an injury.
42062	long-term strengthening of neuromuscular junction	P	Any process that results in an increase in the efficacy of transmission at a neuromuscular synapse.
42063	gliogenesis	P	The process that results in the generation of glial cells. This includes the production of glial progenitors and their differentiation into mature glia.
42065	glial cell growth	P	Growth of glial cells, non-neuronal cells that provide support and nutrition, maintain homeostasis, form myelin, and participate in signal transmission in the nervous system.
42066	perineurial glial growth	P	Glial cell growth that occurs in the perineurium, a cell layer that ensheaths projections of peripheral nerves, such as motor axons.
42067	establishment of ommatidial planar polarity	P	The specification of polarized ommatidia. Ommatidia occur in two chiral forms. The trapezoidal arrangement of photoreceptors in the dorsal part of the eye is the mirror image of that in the ventral part.
42068	regulation of pteridine metabolic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving pteridine.
42069	regulation of catecholamine metabolic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving catecholamines.
42070	maintenance of oocyte nucleus location involved in oocyte dorsal/ventral axis specification	P	Maintenance of the oocyte nucleus in a particular position within the cell during the establishment and maintenance of the axes of the oocyte. An example of this process is found In Drosophila melanogaster.
42071	leucokinin receptor activity	F	Combining with a leucokinin, any of several octapeptide hormones found in insects, and transmitting the signal to initiate a change in cell activity.
42073	intraciliary transport	P	The bidirectional movement of large protein complexes along microtubules within a cilium, mediated by motor proteins.
42074	cell migration involved in gastrulation	P	The migration of individual cells within the blastocyst to help establish the multi-layered body plan of the organism (gastrulation). For example, the migration of cells from the surface to the interior of the embryo (ingression).
42075	nickel incorporation into nickel-iron-sulfur cluster via pentakis-L-cysteinyl L-histidino nickel tetrairon pentasulfide	P	The incorporation of nickel into a nickel-iron-sulfur cluster via pentakis-L-cysteinyl L-histidino nickel tetrairon pentasulfide, found in carbon monoxide dehydrogenase.
42076	protein phosphate-linked glycosylation	P	The glycosylation of peptidyl-amino acids through a phosphoester bond forming, for example, GlcNAc-alpha-1-P-Ser residues.
42077	protein phosphate-linked glycosylation via serine	P	The glycosylation of peptidyl-serine through a phosphoester bond forming, for example, GlcNAc-alpha-1-P-Ser residues.
42078	germ-line stem cell division	P	The self-renewing division of a germline stem cell to produce a daughter stem cell and a daughter germ cell, which will divide to form the gametes.
42081	GSI anchor metabolic process	P	The chemical reactions and pathways involving glycosylsphingolipidinositol (GSI) anchors, which attach membrane proteins to the lipid bilayer of the cell membrane.
42082	GSI anchor biosynthetic process	P	The chemical reactions and pathways resulting in the formation of a glycosylsphingolipidinositol (GSI) anchor that attaches some membrane proteins to the lipid bilayer of the cell membrane. The sphingolipid group is linked, via the C-6 hydroxyl residue of inositol to a carbohydrate chain which is itself linked to the protein via a ethanolamine phosphate group, its amino group forming an amide linkage with the C-terminal carboxyl of the protein. Some GSI anchors have variants on this canonical linkage.
42083	5,10-methylenetetrahydrofolate-dependent methyltransferase activity	F	Catalysis of the transfer of a methyl group to an acceptor molecule; dependent on the presence of 5,10-methylenetetrahydrofolate.
42084	5-methyltetrahydrofolate-dependent methyltransferase activity	F	Catalysis of the transfer of a methyl group to an acceptor molecule; dependent on the presence of 5-methyltetrahydrofolate.
42085	5-methyltetrahydropteroyltri-L-glutamate-dependent methyltransferase activity	F	Catalysis of the transfer of a methyl group to an acceptor molecule; dependent on the presence of 5-methyltetrahydropteroyltri-L-glutamate.
42086	5-methyl-5,6,7,8-tetrahydromethanopterin-dependent methyltransferase activity	F	Catalysis of the transfer of a methyl group to an acceptor molecule, dependent on the presence of 5-methyl-5,6,7,8-tetrahydromethanopterin.
42088	T-helper 1 type immune response	P	An immune response which is associated with resistance to intracellular bacteria, fungi, and protozoa, and pathological conditions such as arthritis, and which is typically orchestrated by the production of particular cytokines by T-helper 1 cells, most notably interferon-gamma, IL-2, and lymphotoxin.
42089	cytokine biosynthetic process	P	The chemical reactions and pathways resulting in the formation of cytokines, any of a group of proteins that function to control the survival, growth and differentiation of tissues and cells, and which have autocrine and paracrine activity.
42090	interleukin-12 biosynthetic process	P	The chemical reactions and pathways resulting in the formation of interleukin-12.
42091	interleukin-10 biosynthetic process	P	The chemical reactions and pathways resulting in the formation of interleukin-10.
42092	type 2 immune response	P	An immune response which is associated with resistance to extracellular organisms such as helminths and pathological conditions such as allergy, which is orchestrated by the production of particular cytokines, most notably IL-4, IL-5, IL-10, and IL-13, by any of a variety of cell types including T-helper 2 cells, eosinophils, basophils, mast cells, and nuocytes, resulting in enhanced production of certain antibody isotypes and other effects.
42093	T-helper cell differentiation	P	The process in which a relatively unspecialized thymocyte acquires specialized features of a T-helper cell.
42094	interleukin-2 biosynthetic process	P	The chemical reactions and pathways resulting in the formation of interleukin-2.
42095	interferon-gamma biosynthetic process	P	The chemical reactions and pathways resulting in the formation of interferon-gamma. Interferon gamma is the only member of the type II interferon found so far.
42097	interleukin-4 biosynthetic process	P	The chemical reactions and pathways resulting in the formation of interleukin-4.
42098	T cell proliferation	P	The expansion of a T cell population by cell division. Follows T cell activation.
42100	B cell proliferation	P	The expansion of a B cell population by cell division. Follows B cell activation.
42101	T cell receptor complex	C	A protein complex that contains a disulfide-linked heterodimer of T cell receptor (TCR) chains, which are members of the immunoglobulin superfamily, and mediates antigen recognition, ultimately resulting in T cell activation. The TCR heterodimer is associated with the CD3 complex, which consists of the nonpolymorphic polypeptides gamma, delta, epsilon, zeta, and, in some cases, eta (an RNA splice variant of zeta) or Fc epsilon chains.
42102	positive regulation of T cell proliferation	P	Any process that activates or increases the rate or extent of T cell proliferation.
42103	positive regulation of T cell homeostatic proliferation	P	Any process that activates or increases the rate or extent of resting T cell proliferation.
42104	positive regulation of activated T cell proliferation	P	Any process that activates or increases the rate or extent of activated T cell proliferation.
42105	alpha-beta T cell receptor complex	C	A T cell receptor complex in which the TCR heterodimer comprises alpha and beta chains, associated with the CD3 complex; recognizes a complex consisting of an antigen-derived peptide bound to a class I or class II MHC protein.
42106	gamma-delta T cell receptor complex	C	A T cell receptor complex in which the TCR heterodimer comprises gamma and delta chains, associated with the CD3 complex; recognizes antigen directly, without a requirement for processing and presentation by an MHC protein.
42107	cytokine metabolic process	P	The chemical reactions and pathways involving cytokines, any of a group of proteins or glycoproteins that function to control the survival, growth and differentiation of tissues and cells, and which have autocrine and paracrine activity.
42108	positive regulation of cytokine biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cytokines.
42109	lymphotoxin A biosynthetic process	P	The chemical reactions and pathways resulting in the formation of the cytokine lymphotoxin A.
42110	T cell activation	P	The change in morphology and behavior of a mature or immature T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.
42113	B cell activation	P	The change in morphology and behavior of a mature or immature B cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.
42116	macrophage activation	P	A change in morphology and behavior of a macrophage resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor.
42117	monocyte activation	P	The change in morphology and behavior of a monocyte resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor.
42118	endothelial cell activation	P	The change in morphology and behavior of an endothelial cell resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor.
42119	neutrophil activation	P	The change in morphology and behavior of a neutrophil resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor.
42120	alginic acid metabolic process	P	The chemical reactions and pathways involving alginic acid, a hydrophilic polysaccharide occurring in, for example, the cell walls of brown algae (brown seaweeds).
42121	alginic acid biosynthetic process	P	The chemical reactions and pathways resulting in the formation of alginic acid, a hydrophilic polysaccharide occurring in, for example, the cell walls of brown algae (brown seaweeds).
42122	alginic acid catabolic process	P	The chemical reactions and pathways resulting in the breakdown of alginic acid, a hydrophilic polysaccharide occurring in, for example, the cell walls of brown algae (brown seaweeds).
42123	glucanosyltransferase activity	F	Catalysis of the splitting and linkage of glucan molecules, resulting in glucan chain elongation.
42124	1,3-beta-glucanosyltransferase activity	F	Catalysis of the splitting and linkage of (1->3)-beta-D-glucan molecules, resulting in (1->3)-beta-D-glucan chain elongation.
42125	protein galactosylation	P	The addition of a galactose molecule to a protein amino acid.
42126	nitrate metabolic process	P	The chemical reactions and pathways involving nitrates, inorganic or organic salts and esters of nitric acid.
42127	regulation of cell proliferation	P	Any process that modulates the frequency, rate or extent of cell proliferation.
42128	nitrate assimilation	P	The nitrogen metabolic process that encompasses the uptake of nitrate from the environment and reduction to ammonia, and results in the incorporation of nitrogen derived from nitrate into cellular substances.
42129	regulation of T cell proliferation	P	Any process that modulates the frequency, rate or extent of T cell proliferation.
42130	negative regulation of T cell proliferation	P	Any process that stops, prevents or reduces the rate or extent of T cell proliferation.
42131	thiamine phosphate phosphatase activity	F	Catalysis of the reaction: thiamine phosphate + H2O = thiamine + phosphate.
42132	fructose 1,6-bisphosphate 1-phosphatase activity	F	Catalysis of the reaction: D-fructose 1,6-bisphosphate + H2O = D-fructose 6-phosphate + phosphate.
42133	neurotransmitter metabolic process	P	The chemical reactions and pathways involving neurotransmitters, any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell.
42134	rRNA primary transcript binding	F	Interacting selectively and non-covalently with an unprocessed ribosomal RNA transcript.
42135	neurotransmitter catabolic process	P	The chemical reactions and pathways resulting in the breakdown of any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell.
42136	neurotransmitter biosynthetic process	P	The chemical reactions and pathways resulting in the formation of any of a group of substances that are released on excitation from the axon terminal of a presynaptic neuron of the central or peripheral nervous system and travel across the synaptic cleft to either excite or inhibit the target cell.
42137	sequestering of neurotransmitter	P	The process of binding or confining a neurotransmitter such that it is separated from other components of a biological system.
42138	meiotic DNA double-strand break formation	P	The cell cycle process in which double-strand breaks are generated at defined hotspots throughout the genome during meiosis I. This results in the initiation of meiotic recombination.
42139	early meiotic recombination nodule assembly	P	During meiosis, the aggregation, arrangement and bonding together of strand exchange proteins (recombinases) to form small, electron dense structures in association with meiotic chromosomes during leptotene and zygotene.
42140	late meiotic recombination nodule assembly	P	During meiosis, the aggregation, arrangement and bonding together of strand exchange proteins (recombinases) to form small, electron dense structures in association with meiotic chromosomes during pachytene. Involved in the catalysis crossing over.
42144	vacuole fusion, non-autophagic	P	The fusion of two vacuole membranes to form a single vacuole.
42147	retrograde transport, endosome to Golgi	P	The directed movement of membrane-bounded vesicles from endosomes back to the trans-Golgi network where they are recycled for further rounds of transport.
42148	strand invasion	P	The process in which the nucleoprotein complex (composed of the broken single-strand DNA and the recombinase) searches and identifies a region of homology in intact duplex DNA. The broken single-strand DNA displaces the like strand and forms Watson-Crick base pairs with its complement, forming a duplex in which each strand is from one of the two recombining DNA molecules.
42149	cellular response to glucose starvation	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of glucose.
42150	plasmid recombination	P	A process of DNA recombination occurring within a plasmid or between plasmids and other plasmids or DNA molecules.
42151	nematocyst	C	An organelle found in cnidoblast (nematoblast) cells. When matured, these stinging organelles store toxins and can deliver them when the cnidocil (a short extension of the cnidocyst) is stimulated by a prey or another stimulus.
42152	RNA-mediated DNA recombination	P	The reverse transcription of an RNA molecule followed by recombination between the resultant cDNA and its homologous chromosomal allele.
42157	lipoprotein metabolic process	P	The chemical reactions and pathways involving any conjugated, water-soluble protein in which the nonprotein group consists of a lipid or lipids.
42158	lipoprotein biosynthetic process	P	The chemical reactions and pathways resulting in the formation of any conjugated, water-soluble protein in which the nonprotein group consists of a lipid or lipids.
42159	lipoprotein catabolic process	P	The chemical reactions and pathways resulting in the breakdown of any conjugated, water-soluble protein in which the nonprotein group consists of a lipid or lipids.
42160	lipoprotein modification	P	The chemical reactions and pathways resulting in the covalent alteration of one or more amino acid or lipid residues occurring in a lipoprotein, any conjugated, water-soluble protein in which the nonprotein group consists of a lipid or lipids.
42161	lipoprotein oxidation	P	The modification of a lipoprotein by oxidation of one or more amino acids or the lipid group.
42162	telomeric DNA binding	F	Interacting selectively and non-covalently with a telomere, a specific structure at the end of a linear chromosome required for the integrity and maintenance of the end.
42163	interleukin-12 beta subunit binding	F	Interacting selectively and non-covalently with the beta subunit of interleukin-12.
42164	interleukin-12 alpha subunit binding	F	Interacting selectively and non-covalently with the alpha subunit of interleukin-12.
42165	neurotransmitter binding	F	Interacting selectively and non-covalently with a neurotransmitter, any chemical substance that is capable of transmitting (or inhibiting the transmission of) a nerve impulse from a neuron to another cell.
42166	acetylcholine binding	F	Interacting selectively and non-covalently with acetylcholine, an acetic acid ester of the organic base choline that functions as a neurotransmitter, released at the synapses of parasympathetic nerves and at neuromuscular junctions.
42167	heme catabolic process	P	The chemical reactions and pathways resulting in the breakdown of heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring.
42168	heme metabolic process	P	The chemical reactions and pathways involving heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring.
42169	SH2 domain binding	F	Interacting selectively and non-covalently with a SH2 domain (Src homology 2) of a protein, a protein domain of about 100 amino-acid residues and belonging to the alpha + beta domain class.
42170	plastid membrane	C	Either of the lipid bilayers that surround a plastid and form the plastid envelope.
42171	lysophosphatidic acid acyltransferase activity	F	Catalysis of the transfer of acyl groups from an acyl-CoA to lysophosphatidic acid to form phosphatidic acid.
42173	regulation of sporulation resulting in formation of a cellular spore	P	Any process that modulates the frequency, rate or extent of spore formation.
42174	negative regulation of sporulation resulting in formation of a cellular spore	P	Any process that stops, prevents, or reduces the frequency, rate or extent of sporulation.
42175	nuclear outer membrane-endoplasmic reticulum membrane network	C	The continuous network of membranes encompassing the nuclear outer membrane and the endoplasmic reticulum membrane.
42176	regulation of protein catabolic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds.
42177	negative regulation of protein catabolic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds.
42178	xenobiotic catabolic process	P	The chemical reactions and pathways resulting in the breakdown of a xenobiotic compound, a compound foreign to living organisms. Used of chemical compounds, e.g. a xenobiotic chemical, such as a pesticide.
42179	nicotine biosynthetic process	P	The chemical reactions and pathways resulting in the formation of nicotine, (S)(-)-3-(1-methyl-2-pyrrolidinyl)pyridine.
42180	cellular ketone metabolic process	P	The chemical reactions and pathways involving any of a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms, as carried out by individual cells. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups.
42181	ketone biosynthetic process	P	The chemical reactions and pathways resulting in the formation of ketones, a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups.
42182	ketone catabolic process	P	The chemical reactions and pathways resulting in the breakdown of ketones, a class of organic compounds that contain the carbonyl group, CO, and in which the carbonyl group is bonded only to carbon atoms. The general formula for a ketone is RCOR, where R and R are alkyl or aryl groups.
42183	formate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of formate, also known as methanoate, the anion HCOO- derived from methanoic (formic) acid.
42184	xylene catabolic process	P	The chemical reactions and pathways resulting in the breakdown of xylene, a mixture of three colorless, aromatic hydrocarbon liquids, ortho-, meta- and para-xylene.
42185	m-xylene catabolic process	P	The chemical reactions and pathways resulting in the breakdown of m-xylene, 1,3-dimethylbenzene, a colorless, liquid aromatic hydrocarbon.
42186	o-xylene catabolic process	P	The chemical reactions and pathways resulting in the breakdown of o-xylene, (1,2-dimethylbenzene) a colorless, liquid aromatic hydrocarbon.
42187	p-xylene catabolic process	P	The chemical reactions and pathways resulting in the breakdown of p-xylene (1,4-dimethylbenzene), a colorless, liquid aromatic hydrocarbon.
42188	1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane catabolic process	P	The chemical reactions and pathways resulting in the breakdown of 1,1,1-trichloro-2,2-bis-(4-chlorophenyl)ethane (DDT), a chlorinated broad spectrum contact insecticide.
42189	vanillin biosynthetic process	P	The chemical reactions and pathways resulting in the formation of vanillin, an aromatic hydrocarbon which occurs naturally in black vanilla bean pods.
42190	vanillin catabolic process	P	The chemical reactions and pathways resulting in the breakdown of vanillin, an aromatic hydrocarbon which occurs naturally in black vanilla bean pods.
42191	methylmercury metabolic process	P	The chemical reactions and pathways involving methylmercury (MeHg+), a highly toxic organometal which can accumulate in tissues, particularly in fish species.
42192	methylmercury biosynthetic process	P	The chemical reactions and pathways resulting in the formation of methylmercury (MeHg+), a highly toxic organometal.
42193	methylmercury catabolic process	P	The chemical reactions and pathways resulting in the breakdown of methylmercury (MeHg+), a highly toxic organometal.
42194	quinate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of quinate, the anion of quinic acid.
42195	aerobic gallate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of gallate, the anion of gallic acid, in the presence of oxygen.
42196	chlorinated hydrocarbon metabolic process	P	The chemical reactions and pathways involving chlorinated hydrocarbons, any hydrocarbon with one or more chlorine atoms attached to it.
42197	halogenated hydrocarbon metabolic process	P	The chemical reactions and pathways involving halogenated hydrocarbons, any hydrocarbon with one or more halogen atoms attached to it. Halogens include fluorine, chlorine, bromine and iodine.
42198	nylon metabolic process	P	The chemical reactions and pathways involving nylon, a polymer where the main polymer chain comprises recurring amide groups; these compounds are generally formed from combinations of diamines, diacids and amino acids.
42199	cyanuric acid metabolic process	P	The chemical reactions and pathways involving cyanuric acid, a suspected gastrointestinal or liver toxicant, and a potential degradation product of triazine herbicides, such as atrazine and simazine. It is widely used for the stabilization of available chlorine in swimming pool water and is also the starting compound for the synthesis of many organic derivatives.
42200	cyanuric acid catabolic process	P	The chemical reactions and pathways resulting in the breakdown of cyanuric acid, a potential degradation product of triazine herbicides.
42201	N-cyclopropylmelamine metabolic process	P	The chemical reactions and pathways involving N-cyclopropylmelamine, a triazine compound commonly used as an insect growth regulator insecticide.
42202	N-cyclopropylmelamine catabolic process	P	The chemical reactions and pathways resulting in the breakdown of N-cyclopropylmelamine, a triazine compound commonly used as an insecticide.
42203	toluene catabolic process	P	The chemical reactions and pathways resulting in the breakdown of toluene, a volatile monoaromatic hydrocarbon found in crude petroleum and petroleum products.
42204	s-triazine compound catabolic process	P	The chemical reactions and pathways resulting in the breakdown of any s-triazine compound. These compounds include many pesticides of widespread use in agriculture, and are characterized by a symmetrical hexameric ring consisting of alternating carbon and nitrogen atoms.
42205	chlorinated hydrocarbon catabolic process	P	The chemical reactions and pathways resulting in the breakdown of chlorinated hydrocarbons, any hydrocarbon with one or more chlorine atoms attached to it.
42206	halogenated hydrocarbon catabolic process	P	The chemical reactions and pathways resulting in the breakdown of halogenated hydrocarbons, any hydrocarbon with one or more halogen atoms attached to it.
42207	styrene catabolic process	P	The chemical reactions and pathways resulting in the breakdown of styrene, an aromatic hydrocarbon liquid used in the manufacture of polystyrene.
42208	propylene catabolic process	P	The chemical reactions and pathways resulting in the breakdown of propylene, an alkene produced by catalytic or thermal cracking of hydrocarbons or as a by-product of petroleum refining.
42209	orcinol catabolic process	P	The chemical reactions and pathways resulting in the breakdown of orcinol (5-methyl-1,3-benzenediol), an aromatic compound derived from the fermentation of lichen and synthesized by some higher plants.
42210	octamethylcyclotetrasiloxane catabolic process to dimethylsilanediol	P	The anaerobic chemical reactions and pathways resulting in the breakdown of octamethylcyclotetrasiloxane into dimethylsilanediol. The former is a tetramer of the latter.
42211	dimethylsilanediol catabolic process	P	The aerobic chemical reactions and pathways resulting in the breakdown of dimethylsilanediol, the smallest member of the dialkylsilanediols. Dimethylsilanediol is the monomer of polydimethylsiloxane, a compound which can be found in a wide range of industrial and consumer products.
42212	cresol metabolic process	P	The chemical reactions and pathways involving cresol, a mixture of the aromatic alcohol isoforms o-, p-, and m-cresol, which is obtained from coal tar or petroleum. The isomers are used as disinfectants, textile scouring agents, surfactants and as intermediates in the manufacture of salicylaldehyde, coumarin, and herbicides as well as being a major component of creosote.
42213	m-cresol catabolic process	P	The chemical reactions and pathways resulting in the breakdown of m-cresol (3-hydroxytoluene), the meta-isoform of cresol.
42214	terpene metabolic process	P	The chemical reactions and pathways involving terpenes, any of a large group of hydrocarbons that are made up of isoprene (C5H8) units which may be cyclic, acyclic or multicyclic, saturated or unsaturated, and may contain various functional groups.
42215	anaerobic phenol-containing compound metabolic process	P	The chemical reactions and pathways involving a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring, in the absence of oxygen.
42216	phenanthrene catabolic process	P	The chemical reactions and pathways resulting in the breakdown of phenanthrene, a tricyclic aromatic hydrocarbon.
42217	1-aminocyclopropane-1-carboxylate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of 1-aminocyclopropane-1-carboxylate, a natural product found in plant tissues. It is a key intermediate in the biosynthesis of ethylene (ethene), a fruit-ripening hormone in plants.
42218	1-aminocyclopropane-1-carboxylate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of 1-aminocyclopropane-1-carboxylate, a natural product found in plant tissues. It is a key intermediate in the biosynthesis of ethylene (ethene), a fruit-ripening hormone in plants.
42219	cellular modified amino acid catabolic process	P	The chemical reactions and pathways resulting in the breakdown of compounds derived from amino acids, organic acids containing one or more amino substituents.
42220	response to cocaine	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cocaine stimulus. Cocaine is a crystalline alkaloid obtained from the leaves of the coca plant.
42221	response to chemical	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemical stimulus.
42222	interleukin-1 biosynthetic process	P	The chemical reactions and pathways resulting in the formation of interleukin-1, an interleukin produced mainly by activated macrophages. It is involved in the inflammatory response, and is identified as an endogenous pyrogen.
42223	interleukin-3 biosynthetic process	P	The chemical reactions and pathways resulting in the formation of interleukin-3.
42225	interleukin-5 biosynthetic process	P	The chemical reactions and pathways resulting in the formation of interleukin-5.
42226	interleukin-6 biosynthetic process	P	The chemical reactions and pathways resulting in the formation of interleukin-6.
42227	interleukin-7 biosynthetic process	P	The chemical reactions and pathways resulting in the formation of interleukin-7.
42228	interleukin-8 biosynthetic process	P	The chemical reactions and pathways resulting in the formation of interleukin-8.
42229	interleukin-9 biosynthetic process	P	The chemical reactions and pathways resulting in the formation of interleukin-9.
42230	interleukin-11 biosynthetic process	P	The chemical reactions and pathways resulting in the formation of interleukin-11.
42231	interleukin-13 biosynthetic process	P	The chemical reactions and pathways resulting in the formation of interleukin-13.
42232	interleukin-14 biosynthetic process	P	The chemical reactions and pathways resulting in the formation of interleukin-14.
42233	interleukin-15 biosynthetic process	P	The chemical reactions and pathways resulting in the formation of interleukin-15.
42234	interleukin-16 biosynthetic process	P	The chemical reactions and pathways resulting in the formation of interleukin-16.
42235	interleukin-17 biosynthetic process	P	The chemical reactions and pathways resulting in the formation of any member of the interleukin-17 family of cytokines.
42236	interleukin-19 biosynthetic process	P	The chemical reactions and pathways resulting in the formation of interleukin-19.
42237	interleukin-20 biosynthetic process	P	The chemical reactions and pathways resulting in the formation of interleukin-20.
42238	interleukin-21 biosynthetic process	P	The chemical reactions and pathways resulting in the formation of interleukin-21.
42239	interleukin-22 biosynthetic process	P	The chemical reactions and pathways resulting in the formation of interleukin-22.
42240	interleukin-23 biosynthetic process	P	The chemical reactions and pathways resulting in the formation of interleukin-23.
42241	interleukin-18 biosynthetic process	P	The chemical reactions and pathways resulting in the formation of interleukin-18.
42242	cobyrinic acid a,c-diamide synthase activity	F	Catalysis of the conversion of cobyrinic acid to cobyrinic acid a,c-diamide via the intermediate formation of cobyrinic acid c-monoamide.
42243	asexual spore wall assembly	P	The aggregation, arrangement and bonding together of a set of components to form an asexual spore wall, the specialized envelope lying outside the cell membrane of a spore derived from an asexual process. Examples of this process are found in Bacterial and Fungal species.
42244	spore wall assembly	P	The aggregation, arrangement and bonding together of a set of components to form a spore wall; a spore wall is the specialized envelope lying outside the cell membrane of a spore.
42245	RNA repair	P	Any process that results in the repair of damaged RNA.
42246	tissue regeneration	P	The regrowth of lost or destroyed tissues.
42247	establishment of planar polarity of follicular epithelium	P	Coordinated organization of groups of cells in the plane of a follicular epithelium, such that they all orient to similar coordinates.
42248	maintenance of polarity of follicular epithelium	P	The maintenance of an established polarized follicular epithelial sheet.
42249	establishment of planar polarity of embryonic epithelium	P	Coordinated organization of groups of cells in the plane of an embryonic epithelium, such that they all orient to similar coordinates.
42250	maintenance of polarity of embryonic epithelium	P	The maintenance of an established polarized embryonic epithelial sheet.
42251	maintenance of polarity of larval imaginal disc epithelium	P	The maintenance of an established polarized larval imaginal disc epithelium.
42252	establishment of planar polarity of larval imaginal disc epithelium	P	Coordinated organization of groups of cells in the plane of a larval imaginal disc epithelium, such that they all orient to similar coordinates.
42253	granulocyte macrophage colony-stimulating factor biosynthetic process	P	The chemical reactions and pathways resulting in the formation of granulocyte macrophage colony-stimulating factor, cytokines that act in hemopoiesis by controlling the production, differentiation, and function of two related white cell populations, granulocytes and monocytes-macrophages.
42254	ribosome biogenesis	P	A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits; includes transport to the sites of protein synthesis.
42255	ribosome assembly	P	The aggregation, arrangement and bonding together of the mature ribosome and of its subunits.
42256	mature ribosome assembly	P	The aggregation, arrangement and bonding together of the large and small ribosomal subunits into a functional ribosome.
42258	molybdenum incorporation via L-serinyl molybdopterin guanine dinucleotide	P	The incorporation of molybdenum into a protein via L-serinyl molybdopterin guanine dinucleotide.
42259	peptidyl-L-beta-methylthioasparagine biosynthetic process from peptidyl-asparagine	P	The modification of peptidyl-asparagine to form peptidyl-L-beta-methylthioasparagine, typical of bacterial ribosomal protein S12.
42262	DNA protection	P	Any process in which DNA is protected from damage by, for example, oxidative stress.
42263	neuropeptide F receptor activity	F	Combining with neuropeptide F and transmitting the signal within the cell to initiate a change in cell activity. Neuropeptide F is an arthropod peptide of more than 28 residues (typically 28-45) with a consensus C-terminal RxRFamide (commonly RPRFa, but also RVRFa.
42264	peptidyl-aspartic acid hydroxylation	P	The hydroxylation of peptidyl-aspartic acid to form peptidyl-hydroxyaspartic acid.
42265	peptidyl-asparagine hydroxylation	P	The hydroxylation of peptidyl-asparagine to form peptidyl-hydroxyasparagine.
42267	natural killer cell mediated cytotoxicity	P	The directed killing of a target cell by a natural killer cell through the release of granules containing cytotoxic mediators or through the engagement of death receptors.
42268	regulation of cytolysis	P	Any process that modulates the frequency, rate or extent of the rupture of cell membranes and the loss of cytoplasm.
42269	regulation of natural killer cell mediated cytotoxicity	P	Any process that modulates the frequency, rate, or extent of natural killer cell mediated cytotoxicity.
42270	protection from natural killer cell mediated cytotoxicity	P	The process of protecting a cell from natural killer cell mediated cytotoxicity.
42271	susceptibility to natural killer cell mediated cytotoxicity	P	The process of causing a cell to become susceptible to natural killer cell mediated cytotoxicity.
42272	nuclear RNA export factor complex	C	A protein complex that contains two proteins (know in several organisms, including Drosophila, as NXF1 and NXF2) and is required for the export of the majority of mRNAs from the nucleus to the cytoplasm; localized in the nucleoplasm and at both the nucleoplasmic and cytoplasmic faces of the nuclear pore complex; shuttles between the nucleus and the cytoplasm.
42273	ribosomal large subunit biogenesis	P	A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a large ribosomal subunit; includes transport to the sites of protein synthesis.
42274	ribosomal small subunit biogenesis	P	A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a small ribosomal subunit; includes transport to the sites of protein synthesis.
42275	error-free postreplication DNA repair	P	The conversion of DNA-damage induced single-stranded gaps into large molecular weight DNA via processes such as template switching, which does not remove the replication-blocking lesions but does not increase the endogenous mutation rate.
42276	error-prone translesion synthesis	P	The conversion of DNA-damage induced single-stranded gaps into large molecular weight DNA after replication by using a specialized DNA polymerase or replication complex to insert a defined nucleotide across the lesion. This process does not remove the replication-blocking lesions and causes an increase in the endogenous mutation level. For example, in E. coli, a low fidelity DNA polymerase, pol V, copies lesions that block replication fork progress. This produces mutations specifically targeted to DNA template damage sites, but it can also produce mutations at undamaged sites.
42277	peptide binding	F	Interacting selectively and non-covalently with peptides, any of a group of organic compounds comprising two or more amino acids linked by peptide bonds.
42278	purine nucleoside metabolic process	P	The chemical reactions and pathways involving one of a family of organic molecules consisting of a purine base covalently bonded to a sugar ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside).
42279	nitrite reductase (cytochrome, ammonia-forming) activity	F	Catalysis of the reaction: NH3 + 2 H2O + 6 ferricytochrome c = nitrite + 6 ferrocytochrome c + 7 H+.
42281	dolichyl pyrophosphate Man9GlcNAc2 alpha-1,3-glucosyltransferase activity	F	Catalysis of the addition of the first glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation; the transfer of glucose from dolichyl phosphate glucose (Dol-P-Glc) on to the lipid-linked oligosaccharide Man(9)GlcNAc(2)-PP-Dol.
42282	hydroxymethylglutaryl-CoA reductase activity	F	Catalysis of the reaction: (R)-mevalonate + CoA + 2 NAD(+) = (S)-3-hydroxy-3-methylglutaryl-CoA + 2 H(+) + 2 NADH.
42283	dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase activity	F	Catalysis of the addition of the second glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation; the transfer of glucose from dolichyl phosphate glucose (Dol-P-Glc) on to the lipid-linked oligosaccharide Glc(1)Man(9)GlcNAc(2)-PP-Dol.
42284	sphingolipid delta-4 desaturase activity	F	Catalysis of the introduction of a trans double bond between C4 and C5 of the long chain base region of a sphingolipid. Sphingolipids are composed of a long chain base (LCB) amide-linked to a very long chain fatty acid.
42285	xylosyltransferase activity	F	Catalysis of the transfer of a xylosyl group to an acceptor molecule, typically another carbohydrate or a lipid.
42286	glutamate-1-semialdehyde 2,1-aminomutase activity	F	Catalysis of the reaction: (S)-4-amino-5-oxopentanoate = 5-aminolevulinate.
42287	MHC protein binding	F	Interacting selectively and non-covalently with major histocompatibility complex molecules; a set of molecules displayed on cell surfaces that are responsible for lymphocyte recognition and antigen presentation.
42288	MHC class I protein binding	F	Interacting selectively and non-covalently with major histocompatibility complex class I molecules; a set of molecules displayed on cell surfaces that are responsible for lymphocyte recognition and antigen presentation.
42289	MHC class II protein binding	F	Interacting selectively and non-covalently with major histocompatibility complex class II molecules; a set of molecules displayed on cell surfaces that are responsible for lymphocyte recognition and antigen presentation.
42292	URM1 activating enzyme activity	F	Catalysis of the activation of the small ubiquitin-related modifier URM1, through the formation of an ATP-dependent high-energy thiolester bond.
42293	Hub1 activating enzyme activity	F	Catalysis of the activation of the small ubiquitin-related modifier Hub1, through the formation of an ATP-dependent high-energy thiolester bond.
42294	URM1 transferase activity	F	Catalysis of the transfer of URM1 from one protein to another via the reaction X-URM1 + Y --> Y-URM1 + X, where both X-URM1 and Y-URM1 are covalent linkages.
42296	ISG15 transferase activity	F	Catalysis of the transfer of ISG15 from one protein to another via the reaction X-ISG15 + Y --> Y-ISG15 + X, where both X-ISG15 and Y-ISG15 are covalent linkages.
42297	vocal learning	P	A behavioral process whose outcome is a relatively long-lasting behavioral change whereby an organism modifies innate vocalizations to imitate sounds produced by others.
42299	lupeol synthase activity	F	Catalysis of the reaction: (S)-2,3-epoxysqualene = lupeol. This reaction is the cyclization of (S)-2,3-epoxysqualene (2,3-oxidosqualene) to lupeol.
42300	beta-amyrin synthase activity	F	Catalysis of the reaction: (S)-2,3-epoxysqualene = beta-amyrin. This reaction is the cyclization and rearrangement of (S)-2,3-epoxysqualene (2,3-oxidosqualene) into beta-amyrin.
42301	phosphate ion binding	F	Interacting selectively and non-covalently with phosphate.
42302	structural constituent of cuticle	F	The action of a molecule that contributes to the structural integrity of a cuticle.
42303	molting cycle	P	The periodic casting off and regeneration of an outer covering of cuticle, feathers, hair, horns, skin, etc.
42304	regulation of fatty acid biosynthetic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of fatty acids, any of the aliphatic monocarboxylic acids that can be liberated by hydrolysis from naturally occurring fats and oils.
42305	specification of segmental identity, mandibular segment	P	The specification of the characteristic structures of the mandibular segment following establishment of segment boundaries. Identity is considered to be the aggregate of characteristics by which a structure is recognized.
42306	regulation of protein import into nucleus	P	Any process that modulates the frequency, rate or extent of movement of proteins from the cytoplasm to the nucleus.
42307	positive regulation of protein import into nucleus	P	Any process that activates or increases the frequency, rate or extent of movement of proteins from the cytoplasm into the nucleus.
42308	negative regulation of protein import into nucleus	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the movement of proteins from the cytoplasm into the nucleus.
42309	homoiothermy	P	Any homoeostatic process in which an organism maintains its internal body temperature at a relatively constant value. This is achieved by using metabolic processes to counteract fluctuations in the temperature of the environment.
42310	vasoconstriction	P	A decrease in the diameter of blood vessels, especially arteries, due to constriction of smooth muscle cells that line the vessels, and usually causing an increase in blood pressure.
42311	vasodilation	P	An increase in the internal diameter of blood vessels, especially arterioles or capillaries, due to relaxation of smooth muscle cells that line the vessels, and usually resulting in a decrease in blood pressure.
42312	regulation of vasodilation	P	Any process that modulates the frequency, rate or extent of increases in the diameter of blood vessels.
42313	protein kinase C deactivation	P	Any process resulting in the inhibition or termination of the activity of protein kinase C.
42314	bacteriochlorophyll binding	F	Interacting selectively and non-covalently with bacteriochlorophyll, a form of chlorophyll found in photosynthetic bacteria, such as the purple and green bacteria. There are several types, designated a to g. Bacteriochlorophyll a and bacteriochlorophyll b are structurally similar to the chlorophyll a and chlorophyll b found in plants.
42316	penicillin metabolic process	P	The chemical reactions and pathways involving any antibiotic that contains the condensed beta-lactamthiazolidine ring system. Penicillins are produced naturally during the growth of various microfungi of the genera Penicillium and Aspergillus.
42317	penicillin catabolic process	P	The chemical reactions and pathways resulting in the breakdown of any antibiotic that contains the condensed beta-lactamthiazolidine ring system.
42318	penicillin biosynthetic process	P	The chemical reactions and pathways resulting in the formation of any antibiotic that contains the condensed beta-lactamthiazolidine ring system.
42320	regulation of circadian sleep/wake cycle, REM sleep	P	Any process that modulates the frequency, rate or extent of rapid eye movement (REM) sleep.
42321	negative regulation of circadian sleep/wake cycle, sleep	P	Any process that stops, prevents or reduces the duration or quality of sleep, a readily reversible state of reduced awareness and metabolic activity that occurs periodically in many animals.
42322	negative regulation of circadian sleep/wake cycle, REM sleep	P	Any process that stops, prevents or reduces the duration or quality of rapid eye movement (REM) sleep.
42323	negative regulation of circadian sleep/wake cycle, non-REM sleep	P	Any process that stops, prevents or reduces the duration or quality of non-rapid eye movement (NREM) sleep.
42324	hypocretin receptor binding	F	Interacting selectively and non-covalently with the hypocretin receptor.
42325	regulation of phosphorylation	P	Any process that modulates the frequency, rate or extent of addition of phosphate groups into a molecule.
42326	negative regulation of phosphorylation	P	Any process that stops, prevents or decreases the rate of addition of phosphate groups to a molecule.
42327	positive regulation of phosphorylation	P	Any process that activates or increases the frequency, rate or extent of addition of phosphate groups to a molecule.
42328	heparan sulfate N-acetylglucosaminyltransferase activity	F	Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + heparan sulfate = UDP + (N-acetyl-D-glucosaminyl)-heparan sulfate.
42329	structural constituent of collagen and cuticulin-based cuticle	F	The action of a molecule that contributes to the structural integrity of a collagen and cuticulin-based cuticle. An example of this process is found in Caenorhabditis elegans.
42330	taxis	P	The directed movement of a motile cell or organism in response to an external stimulus.
42331	phototaxis	P	The directed movement of a motile cell or organism in response to light.
42332	gravitaxis	P	The directed movement of a motile cell or organism in response to gravity.
42333	chemotaxis to oxidizable substrate	P	The directed movement of a motile cell or organism in response to the presence of an oxidizable substrate, for example, fructose.
42334	taxis to electron acceptor	P	The directed movement of a motile cell or organism in response to the presence of an alternative electron acceptor, for example, nitrate.
42335	cuticle development	P	The chemical reactions and pathways resulting in the formation of a cuticle, the outer layer of some animals and plants, which acts to prevent water loss.
42337	cuticle development involved in chitin-based cuticle molting cycle	P	The synthesis and deposition of a chitin-based non-cellular, hardened, or membranous secretion from an epithelial sheet, occurring as part of the molting cycle. An example of this is found in Drosophila melanogaster.
42338	cuticle development involved in collagen and cuticulin-based cuticle molting cycle	P	Synthesis and deposition of a collagen and cuticulin-based noncellular, hardened, or membranous secretion from an epithelial sheet, occurring as part of the molting cycle. An example of this process is found in Caenorhabditis elegans.
42339	keratan sulfate metabolic process	P	The chemical reactions and pathways involving keratan sulfate, a glycosaminoglycan with repeat units consisting of beta-1,4-linked D-galactopyranosyl-beta-(1,4)-N-acetyl-D-glucosamine 6-sulfate and with variable amounts of fucose, sialic acid and mannose units; keratan sulfate chains are covalently linked by a glycosidic attachment through the trisaccharide galactosyl-galactosyl-xylose to peptidyl-threonine or serine residues.
42340	keratan sulfate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of keratan sulfate, a glycosaminoglycan with repeat units consisting of beta-1,4-linked D-galactopyranosyl-beta-(1,4)-N-acetyl-D-glucosamine 6-sulfate and with variable amounts of fucose, sialic acid and mannose units; keratan sulfate chains are covalently linked by a glycosidic attachment through the trisaccharide galactosyl-galactosyl-xylose to peptidyl-threonine or serine residues.
42341	cyanogenic glycoside metabolic process	P	The chemical reactions and pathways involving cyanogenic glycosides, any glycoside containing a cyano group that is released as hydrocyanic acid on acid hydrolysis; such compounds occur in the kernels of various fruits.
42342	cyanogenic glycoside catabolic process	P	The chemical reactions and pathways resulting in the breakdown of cyanogenic glycosides, any glycoside containing a cyano group that is released as hydrocyanic acid on acid hydrolysis; such compounds occur in the kernels of various fruits.
42343	indole glucosinolate metabolic process	P	The chemical reactions and pathways resulting in the formation of indole glucosinolates. Glucosinolates are sulfur-containing compounds that have a common structure linked to an R group derived from tryptophan; indoles are biologically active substances based on 2,3-benzopyrrole, formed during the catabolism of tryptophan.
42344	indole glucosinolate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of indole glucosinolates, sulfur-containing compounds that have a common structure linked to an R group derived from tryptophan.
42345	regulation of NF-kappaB import into nucleus	P	Any process that modulates the frequency, rate or extent of the transfer of NF-kappaB, a transcription factor for eukaryotic RNA polymerase II promoters, from the cytoplasm into the nucleus, across the nuclear membrane.
42346	positive regulation of NF-kappaB import into nucleus	P	Any process that activates or increases the frequency, rate or extent of transfer of NF-kappaB, a transcription factor for eukaryotic RNA polymerase II promoters, from the cytoplasm into the nucleus, across the nuclear membrane.
42347	negative regulation of NF-kappaB import into nucleus	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the transfer of NF-kappaB, a transcription factor for eukaryotic RNA polymerase II promoters, from the cytoplasm into the nucleus, across the nuclear membrane.
42348	NF-kappaB import into nucleus	P	The directed movement of NF-kappaB, a transcription factor for eukaryotic RNA polymerase II promoters, from the cytoplasm into the nucleus, across the nuclear membrane.
42349	guiding stereospecific synthesis activity	F	The orientation of free radical substrates in such a way that only a particular stereoisomer is synthesized by an enzyme. Best characterized as a function during lignan biosynthesis.
42350	GDP-L-fucose biosynthetic process	P	The chemical reactions and pathways resulting in the formation of GDP-L-fucose, a substance composed of L-fucose in glycosidic linkage with guanosine diphosphate.
42351	'de novo' GDP-L-fucose biosynthetic process	P	The chemical reactions and pathways resulting in the formation of GDP-L-fucose from GDP-D-mannose via GDP-4-dehydro-6-deoxy-D-mannose, requiring the functions of GDP-mannose 4,6-dehydratase (EC:4.2.1.47) and GDP-L-fucose synthase (EC:1.1.1.271).
42352	GDP-L-fucose salvage	P	The formation of GDP-L-fucose from L-fucose, without de novo synthesis. L-fucose is phosphorylated by fucokinase and then converted by fucose-1-phosphate guanylyltransferase (EC:2.7.7.30).
42353	fucose biosynthetic process	P	The chemical reactions and pathways resulting in the formation of fucose (6-deoxygalactose).
42354	L-fucose metabolic process	P	The chemical reactions and pathways involving L-fucose, 6-deoxy-L-galactose, a sugar that occurs in fucans, a class of polysaccharides in seaweeds, especially Fucus species, and in the cell wall matrix of higher plants.
42355	L-fucose catabolic process	P	The chemical reactions and pathways resulting in the breakdown of L-fucose (6-deoxy-Lgalactose).
42356	GDP-4-dehydro-D-rhamnose reductase activity	F	Catalysis of the reaction: GDP-6-deoxy-D-mannose + NAD(P)+ = GDP-4-dehydro-6-deoxy-D-mannose + NAD(P)H + H+. In the reverse reaction, a mixture of GDP-D-rhamnose and its C-4 epimer is formed.
42357	thiamine diphosphate metabolic process	P	The chemical reactions and pathways involving thiamine diphosphate, a derivative of thiamine (vitamin B1) which acts as a coenzyme in a range of processes including the Krebs cycle.
42358	thiamine diphosphate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of thiamine diphosphate, a derivative of thiamine (vitamin B1) which acts as a coenzyme in a range of processes including the Krebs cycle.
42359	vitamin D metabolic process	P	The chemical reactions and pathways involving vitamin D, any of a group of related, fat-soluble compounds that are derived from delta-5,7 steroids and play a central role in calcium metabolism. Specific forms of vitamin D include calciferol (ergocalciferol; vitamin D2) and cholecalciferol (calciol; vitamin D3).
42360	vitamin E metabolic process	P	The chemical reactions and pathways involving vitamin E, tocopherol, which includes a series of eight structurally similar compounds. Alpha-tocopherol is the most active form in humans and is a powerful biological antioxidant.
42361	menaquinone catabolic process	P	The chemical reactions and pathways resulting in the breakdown of menaquinones, any of the quinone-derived compounds synthesized by intestinal bacteria. Structurally, menaquinones consist of a methylated naphthoquinone ring structure and side chains composed of a variable number of unsaturated isoprenoid residues. Menaquinones have vitamin K activity and are known as vitamin K2.
42362	fat-soluble vitamin biosynthetic process	P	The chemical reactions and pathways resulting in the formation of any of a diverse group of vitamins that are soluble in organic solvents and relatively insoluble in water.
42363	fat-soluble vitamin catabolic process	P	The chemical reactions and pathways resulting in the breakdown of any of a diverse group of vitamins that are soluble in organic solvents and relatively insoluble in water.
42364	water-soluble vitamin biosynthetic process	P	The chemical reactions and pathways resulting in the formation of any of a diverse group of vitamins that are soluble in water.
42365	water-soluble vitamin catabolic process	P	The chemical reactions and pathways resulting in the breakdown of any of a diverse group of vitamins that are soluble in water.
42366	cobalamin catabolic process	P	The chemical reactions and pathways resulting in the breakdown of cobalamin (vitamin B12), a water-soluble vitamin characterized by possession of a corrin nucleus containing a cobalt atom.
42367	biotin catabolic process	P	The chemical reactions and pathways resulting in the breakdown of biotin, cis-tetrahydro-2-oxothieno(3,4-d)imidazoline-4-valeric acid.
42368	vitamin D biosynthetic process	P	The chemical reactions and pathways resulting in the formation of vitamin D, any of a group of related, fat-soluble compounds that are derived from delta-5,7 steroids and play a central role in calcium metabolism. Specific forms of vitamin D include calciferol (ergocalciferol; vitamin D2) and cholecalciferol (calciol; vitamin D3).
42369	vitamin D catabolic process	P	The chemical reactions and pathways resulting in the breakdown of vitamin D, any of a group of related, fat-soluble compounds that are derived from delta-5,7 steroids and play a central role in calcium metabolism. Specific forms of vitamin D include calciferol (ergocalciferol; vitamin D2) and cholecalciferol (calciol; vitamin D3).
42370	thiamine diphosphate dephosphorylation	P	The removal of one or more phosphate groups from thiamine diphosphate, a derivative of thiamine (vitamin B1) which acts as a coenzyme in a range of processes including the Krebs cycle.
42371	vitamin K biosynthetic process	P	The chemical reactions and pathways resulting in the formation of any of the forms of vitamin K, quinone-derived vitamins which are involved in the synthesis of blood-clotting factors in mammals.
42372	phylloquinone biosynthetic process	P	The chemical reactions and pathways resulting in the formation of phylloquinone, vitamin K1, a quinone-derived compound synthesized by green plants.
42373	vitamin K metabolic process	P	The chemical reactions and pathways involving any of the forms of vitamin K, quinone-derived vitamins which are involved in the synthesis of blood-clotting factors in mammals. Vitamin K substances share a methylated naphthoquinone ring structure and vary in the aliphatic side chains attached to the molecule.
42374	phylloquinone metabolic process	P	The chemical reactions and pathways involving phylloquinone, a quinone-derived compound synthesized by green plants. Phylloquinone has vitamin K activity and is known as vitamin K1.
42376	phylloquinone catabolic process	P	The chemical reactions and pathways resulting in the breakdown of phylloquinone, vitamin K1, a quinone-derived compound synthesized by green plants.
42377	vitamin K catabolic process	P	The chemical reactions and pathways resulting in the breakdown of any of the forms of vitamin K, quinone-derived vitamins which are involved in the synthesis of blood-clotting factors in mammals.
42379	chemokine receptor binding	F	Interacting selectively and non-covalently with any chemokine receptor.
42380	hydroxymethylbutenyl pyrophosphate reductase activity	F	Catalysis of the formation of both isopentenyl pyrophosphate and dimethylallyl pyrophosphate from (E)-4-hydroxy-3-methyl-but-2-enyl pyrophosphate.
42381	hemolymph coagulation	P	Any process in which factors in the hemolymph (the invertebrate equivalent of vertebrate blood and lymph) precipitate into insoluble clots in order to prevent loss of body fluid, and at the same time prevent the movement of microbes. Hemolymph coagulation is also part of the invertebrate humoral immune response.
42382	paraspeckles	C	Discrete subnuclear bodies in the interchromatin nucleoplasmic space, often located adjacent to nuclear specks. 10-20 paraspeckles are typically found in human cell nuclei.
42383	sarcolemma	C	The outer membrane of a muscle cell, consisting of the plasma membrane, a covering basement membrane (about 100 nm thick and sometimes common to more than one fiber), and the associated loose network of collagen fibers.
42385	myosin III complex	C	A myosin complex containing a class III myosin heavy chain and associated light chains; myosin III is monomeric myosin that serves as a link between the cytoskeleton and the signaling complex involved in phototransduction, and differs from all other myosins in having an N-terminal kinase domain.
42386	hemocyte differentiation	P	The process in which a relatively unspecialized cell acquires the characteristics of a mature hemocyte. Hemocytes are blood cells associated with a hemocoel (the cavity containing most of the major organs of the arthropod body) which are involved in defense and clotting of hemolymph, but not involved in transport of oxygen.
42387	plasmatocyte differentiation	P	The process in which a hemocyte precursor cell acquires the characteristics of the phagocytic blood-cell type, the plasmatocyte. Plasmatocytes are a class of arthropod hemocytes important in the cellular defense response.
42388	gibberellic acid mediated signaling pathway, G-alpha-dependent	P	A series of molecular signals mediated by the detection of gibberellic acid and dependent on the coupling of the alpha subunit of G proteins to the hormone receptors.
42389	omega-3 fatty acid desaturase activity	F	Catalysis of the introduction of an omega-3 double bond into the fatty acid hydrocarbon chain.
42390	gibberellic acid mediated signaling pathway, G-alpha-independent	P	A series of molecular signals mediated by the detection of gibberellic acid and not dependent on the coupling of the alpha subunit of G proteins to the hormone receptors.
42391	regulation of membrane potential	P	Any process that modulates the establishment or extent of a membrane potential, the electric potential existing across any membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane.
42392	sphingosine-1-phosphate phosphatase activity	F	Catalysis of the reaction: sphingosine 1-phosphate + H2O = sphingosine + phosphate.
42393	histone binding	F	Interacting selectively and non-covalently with a histone, any of a group of water-soluble proteins found in association with the DNA of plant and animal chromosomes. They are involved in the condensation and coiling of chromosomes during cell division and have also been implicated in nonspecific suppression of gene activity.
42395	ecdysis, collagen and cuticulin-based cuticle	P	The shedding of the old collagen and cuticulin-based cuticle fragments during the molting cycle. Examples of this process are found in invertebrates.
42396	phosphagen biosynthetic process	P	The chemical reactions and pathways resulting in the formation of phosphagen, any of a group of guanidine phosphates that occur in muscle and can be used to regenerate ATP from ADP during muscular contraction.
42397	phosphagen catabolic process	P	The chemical reactions and pathways resulting in the breakdown of phosphagen, any of a group of guanidine phosphates that occur in muscle and can be used to regenerate ATP from ADP during muscular contraction.
42398	cellular modified amino acid biosynthetic process	P	The chemical reactions and pathways resulting in the formation of compounds derived from amino acids, organic acids containing one or more amino substituents.
42399	ectoine metabolic process	P	The chemical reactions and pathways involving ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidinecarboxylic acid), a tetrahydropyrimidine commonly synthesized by halophilic bacteria.
42400	ectoine catabolic process	P	The chemical reactions and pathways resulting in the breakdown of ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidinecarboxylic acid), a tetrahydropyrimidine commonly synthesized by halophilic bacteria.
42401	cellular biogenic amine biosynthetic process	P	The chemical reactions and pathways occurring at the level of individual cells resulting in the formation of any of a group of naturally occurring, biologically active amines, such as norepinephrine, histamine, and serotonin, many of which act as neurotransmitters.
42402	cellular biogenic amine catabolic process	P	The chemical reactions and pathways occurring at the level of individual cells resulting in the breakdown of biogenic amines, any of a group of naturally occurring, biologically active amines, such as norepinephrine, histamine, and serotonin, many of which act as neurotransmitters.
42403	thyroid hormone metabolic process	P	The chemical reactions and pathways involving any of the compounds secreted by the thyroid gland, largely thyroxine and triiodothyronine.
42404	thyroid hormone catabolic process	P	The chemical reactions and pathways resulting in the breakdown of any of the compounds secreted by the thyroid gland, largely thyroxine and triiodothyronine.
42405	nuclear inclusion body	C	An intranuclear focus at which aggregated proteins have been sequestered.
42406	extrinsic component of endoplasmic reticulum membrane	C	The component of the endoplasmic reticulum membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
42407	cristae formation	P	The assembly of cristae, the inwards folds of the inner mitochondrial membrane.
42409	caffeoyl-CoA O-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + caffeoyl-CoA = S-adenosyl-L-homocysteine + feruloyl-CoA.
42410	6-carboxyhexanoate-CoA ligase activity	F	Catalysis of the reaction: ATP + CoA + pimelate = AMP + diphosphate + H(+) + pimelyl-CoA.
42412	taurine biosynthetic process	P	The chemical reactions and pathways resulting in the formation of taurine (2-aminoethanesulfonic acid), a sulphur-containing amino acid derivative important in the metabolism of fats.
42413	carnitine catabolic process	P	The chemical reactions and pathways resulting in the breakdown of carnitine (hydroxy-trimethyl aminobutyric acid), a compound that participates in the transfer of acyl groups across the inner mitochondrial membrane.
42414	epinephrine metabolic process	P	The chemical reactions and pathways involving epinephrine, a hormone produced by the medulla of the adrenal glands that increases heart activity, improves the power and prolongs the action of muscles, and increases the rate and depth of breathing. It is synthesized by the methylation of norepinephrine.
42415	norepinephrine metabolic process	P	The chemical reactions and pathways involving norepinephrine, a hormone secreted by the adrenal medulla, and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts in the central nervous system. It is also the demethylated biosynthetic precursor of epinephrine.
42416	dopamine biosynthetic process	P	The chemical reactions and pathways resulting in the formation of dopamine, a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline.
42417	dopamine metabolic process	P	The chemical reactions and pathways involving dopamine, a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline.
42418	epinephrine biosynthetic process	P	The chemical reactions and pathways resulting in the formation of epinephrine, a hormone produced by the medulla of the adrenal glands that increases heart activity, improves the power and prolongs the action of muscles, and increases the rate and depth of breathing. It is synthesized by the methylation of norepinephrine.
42419	epinephrine catabolic process	P	The chemical reactions and pathways resulting in the breakdown of epinephrine, a hormone produced by the medulla of the adrenal glands that increases heart activity, improves the power and prolongs the action of muscles, and increases the rate and depth of breathing. It is synthesized by the methylation of norepinephrine.
42420	dopamine catabolic process	P	The chemical reactions and pathways resulting in the breakdown of dopamine, a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline.
42421	norepinephrine biosynthetic process	P	The chemical reactions and pathways resulting in the formation of norepinephrine, a hormone secreted by the adrenal medulla, and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts in the central nervous system. It is also the demethylated biosynthetic precursor of epinephrine.
42422	norepinephrine catabolic process	P	The chemical reactions and pathways resulting in the breakdown of norepinephrine, a hormone secreted by the adrenal medulla, and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts in the central nervous system. It is also the demethylated biosynthetic precursor of epinephrine.
42423	catecholamine biosynthetic process	P	The chemical reactions and pathways resulting in the formation of any of a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine.
42424	catecholamine catabolic process	P	The chemical reactions and pathways resulting in the breakdown of any of a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine.
42425	choline biosynthetic process	P	The chemical reactions and pathways resulting in the formation of choline (2-hydroxyethyltrimethylammonium), an amino alcohol that occurs widely in living organisms as a constituent of certain types of phospholipids and in the neurotransmitter acetylcholine.
42426	choline catabolic process	P	The chemical reactions and pathways resulting in the breakdown of choline (2-hydroxyethyltrimethylammonium), an amino alcohol that occurs widely in living organisms as a constituent of certain types of phospholipids and in the neurotransmitter acetylcholine.
42427	serotonin biosynthetic process	P	The chemical reactions and pathways resulting in the formation of serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties.
42428	serotonin metabolic process	P	The chemical reactions and pathways involving serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties.
42429	serotonin catabolic process	P	The chemical reactions and pathways resulting in the breakdown of serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties.
42430	indole-containing compound metabolic process	P	The chemical reactions and pathways involving compounds that contain an indole (2,3-benzopyrrole) skeleton.
42431	indole metabolic process	P	The chemical reactions and pathways involving indole (2,3-benzopyrrole), the basis of many biologically active substances (e.g. serotonin, tryptophan).
42432	indole biosynthetic process	P	The chemical reactions and pathways resulting in the formation of indole (2,3-benzopyrrole), the basis of many biologically active substances (e.g. serotonin, tryptophan).
42433	indole catabolic process	P	The chemical reactions and pathways resulting in the breakdown of indole (2,3-benzopyrrole), the basis of many biologically active substances (e.g. serotonin, tryptophan).
42435	indole-containing compound biosynthetic process	P	The chemical reactions and pathways resulting in the formation of compounds that contain an indole (2,3-benzopyrrole) skeleton.
42436	indole-containing compound catabolic process	P	The chemical reactions and pathways resulting in the breakdown of compounds that contain an indole (2,3-benzopyrrole) skeleton.
42437	indoleacetic acid catabolic process	P	The chemical reactions and pathways resulting in the breakdown of indole-3-acetic acid, a compound which functions as a growth regulator in plants.
42438	melanin biosynthetic process	P	The chemical reactions and pathways resulting in the formation of melanins, pigments largely of animal origin. High molecular weight polymers of indole quinone, they are irregular polymeric structures and are divided into three groups: allomelanins in the plant kingdom and eumelanins and phaeomelanins in the animal kingdom.
42439	ethanolamine-containing compound metabolic process	P	The chemical reactions and pathways involving ethanolamine (2-aminoethanol) and compounds derived from it.
42440	pigment metabolic process	P	The chemical reactions and pathways involving pigment, any general or particular coloring matter in living organisms, e.g. melanin.
42441	eye pigment metabolic process	P	The chemical reactions and pathways involving eye pigments, any general or particular coloring matter in living organisms, found or utilized in the eye.
42442	melatonin catabolic process	P	The chemical reactions and pathways resulting in the breakdown of melatonin (N-acetyl-5-methoxytryptamine).
42443	phenylethylamine metabolic process	P	The chemical reactions and pathways involving phenylethylamine, an amine with pharmacological properties similar to those of amphetamine, occurs naturally as a neurotransmitter in the brain, and is present in chocolate and oil of bitter almonds.
42444	phenylethylamine biosynthetic process	P	The chemical reactions and pathways resulting in the formation of phenylethylamine, an amine with pharmacological properties similar to those of amphetamine, occurs naturally as a neurotransmitter in the brain, and is present in chocolate and oil of bitter almonds.
42445	hormone metabolic process	P	The chemical reactions and pathways involving any hormone, naturally occurring substances secreted by specialized cells that affects the metabolism or behavior of other cells possessing functional receptors for the hormone.
42446	hormone biosynthetic process	P	The chemical reactions and pathways resulting in the formation of any hormone, naturally occurring substances secreted by specialized cells that affects the metabolism or behavior of other cells possessing functional receptors for the hormone.
42447	hormone catabolic process	P	The chemical reactions and pathways resulting in the breakdown of any hormone, naturally occurring substances secreted by specialized cells that affects the metabolism or behavior of other cells possessing functional receptors for the hormone.
42448	progesterone metabolic process	P	The chemical reactions and pathways involving progesterone, a steroid hormone produced in the ovary which prepares and maintains the uterus for pregnancy. Also found in plants.
42450	arginine biosynthetic process via ornithine	P	The chemical reactions and pathways resulting in the formation of arginine (2-amino-5-guanidinopentanoic acid) via the intermediate compound ornithine.
42451	purine nucleoside biosynthetic process	P	The chemical reactions and pathways resulting in the formation of any purine nucleoside, one of a family of organic molecules consisting of a purine base covalently bonded to a sugar ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside).
42452	deoxyguanosine biosynthetic process	P	The chemical reactions and pathways resulting in the formation of deoxyguanosine, a nucleoside consisting of the base guanine and the sugar deoxyribose.
42453	deoxyguanosine metabolic process	P	The chemical reactions and pathways involving deoxyguanosine, a nucleoside consisting of the base guanine and the sugar deoxyribose.
42454	ribonucleoside catabolic process	P	The chemical reactions and pathways resulting in the breakdown of any ribonucleoside, a nucleoside in which purine or pyrimidine base is linked to a ribose (beta-D-ribofuranose) molecule.
42455	ribonucleoside biosynthetic process	P	The chemical reactions and pathways resulting in the formation of any ribonucleoside, a nucleoside in which purine or pyrimidine base is linked to a ribose (beta-D-ribofuranose) molecule.
42457	ethylene catabolic process	P	The chemical reactions and pathways resulting in the breakdown of ethylene (C2-H4, ethene), a simple hydrocarbon gas that can function in plants as a growth regulator.
42458	nopaline catabolic process to proline	P	The chemical reactions and pathways resulting in the breakdown of nopaline into other compounds, including proline.
42459	octopine catabolic process to proline	P	The chemical reactions and pathways resulting in the breakdown of octopine into other compounds, including proline.
42461	photoreceptor cell development	P	Development of a photoreceptor, a cell that responds to incident electromagnetic radiation, particularly visible light.
42462	eye photoreceptor cell development	P	Development of a photoreceptor, a sensory cell in the eye that reacts to the presence of light. They usually contain a pigment that undergoes a chemical change when light is absorbed, thus stimulating a nerve.
42463	ocellus photoreceptor cell development	P	Development of photoreceptors, sensory cells that react to the presence of light, found in the ocellus.
42464	dosage compensation by hypoactivation of X chromosome	P	Compensating for the two-fold variation in X:autosome chromosome ratios between sexes by an inactivation of a proportion of genes on both of the X chromosomes of the XX sex, leading to a decrease, of half, of the levels of gene expression from these chromosomes. An example of this process is found in Caenorhabditis elegans.
42465	kinesis	P	The movement of a cell or organism in response to a stimulus in which the rate of movement depends on the intensity (rather than the direction) of the stimulus.
42466	chemokinesis	P	A response by a motile cell to a soluble chemical that involves an increase or decrease in speed (positive or negative orthokinesis) or of frequency of movement or a change in the frequency or magnitude of turning behavior (klinokinesis).
42467	orthokinesis	P	The movement of a cell or organism in response to a stimulus in which the speed or frequency of movement is increased or decreased.
42468	klinokinesis	P	The movement of a cell or organism in response to a stimulus in which the frequency or magnitude of turning behavior is altered.
42469	versicolorin reductase activity	F	Catalysis of the reduction of versicolorin A to sterigmatocystin.
42470	melanosome	C	A tissue-specific, membrane-bounded cytoplasmic organelle within which melanin pigments are synthesized and stored. Melanosomes are synthesized in melanocyte cells.
42471	ear morphogenesis	P	The process in which the anatomical structures of the ear are generated and organized. The ear is the sense organ in vertebrates that is specialized for the detection of sound, and the maintenance of balance. Includes the outer ear and middle ear, which collect and transmit sound waves; and the inner ear, which contains the organs of balance and (except in fish) hearing. Also includes the pinna, the visible part of the outer ear, present in some mammals.
42472	inner ear morphogenesis	P	The process in which the anatomical structures of the inner ear are generated and organized. The inner ear is the structure in vertebrates that contains the organs of balance and hearing. It consists of soft hollow sensory structures (the membranous labyrinth) containing fluid (endolymph) surrounded by fluid (perilymph) and encased in a bony cavity (the bony labyrinth). It consists of two chambers, the sacculus and utriculus, from which arise the cochlea and semicircular canals respectively.
42473	outer ear morphogenesis	P	The process in which the anatomical structures of the outer ear are generated and organized. The outer ear is the part of the ear external to the tympanum (eardrum). It consists of a tube (the external auditory meatus) that directs sound waves on to the tympanum, and may also include the external pinna, which extends beyond the skull.
42474	middle ear morphogenesis	P	The process in which the anatomical structures of the middle ear are generated and organized. The middle ear is the air-filled cavity within the skull of vertebrates that lies between the outer ear and the inner ear. It is linked to the pharynx (and therefore to outside air) via the Eustachian tube and in mammals contains the three ear ossicles, which transmit auditory vibrations from the outer ear (via the tympanum) to the inner ear (via the oval window).
42475	odontogenesis of dentin-containing tooth	P	The process whose specific outcome is the progression of a dentin-containing tooth over time, from its formation to the mature structure. A dentin-containing tooth is a hard, bony organ borne on the jaw or other bone of a vertebrate, and is composed mainly of dentin, a dense calcified substance, covered by a layer of enamel.
42476	odontogenesis	P	The process whose specific outcome is the progression of a tooth or teeth over time, from formation to the mature structure(s). A tooth is any hard bony, calcareous, or chitinous organ found in the mouth or pharynx of an animal and used in procuring or masticating food.
42478	regulation of eye photoreceptor cell development	P	Any process that modulates the frequency, rate or extent of eye photoreceptor development.
42479	positive regulation of eye photoreceptor cell development	P	Any process that activates or increases the frequency, rate or extent of eye photoreceptor development.
42480	negative regulation of eye photoreceptor cell development	P	Any process that stops, prevents, or reduces the frequency, rate or extent of eye photoreceptor development.
42481	regulation of odontogenesis	P	Any process that modulates the frequency, rate or extent of the formation and development of a tooth or teeth.
42482	positive regulation of odontogenesis	P	Any process that activates or increases the frequency, rate or extent of the formation and development of a tooth or teeth.
42483	negative regulation of odontogenesis	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the formation and development of a tooth or teeth.
42487	regulation of odontogenesis of dentin-containing tooth	P	Any process that modulates the frequency, rate or extent of the formation and development of teeth, the hard, bony appendages which are borne on the jaws, or on other bones in the walls of the mouth or pharynx of most vertebrates.
42488	positive regulation of odontogenesis of dentin-containing tooth	P	Any process that activates or increases the frequency, rate or extent of the formation and development of teeth, the hard, bony appendages that are borne on the jaws, or on other bones in the walls of the mouth or pharynx of most vertebrates.
42489	negative regulation of odontogenesis of dentin-containing tooth	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the formation and development of teeth, the hard, bony appendages which are borne on the jaws, or on other bones in the walls of the mouth or pharynx.
42490	mechanoreceptor differentiation	P	The process in which a relatively unspecialized cell acquires specialized features of a mechanoreceptor, a cell specialized to transduce mechanical stimuli and relay that information centrally in the nervous system.
42491	auditory receptor cell differentiation	P	The process in which a relatively unspecialized cell acquires specialized features of an auditory hair cell.
42492	gamma-delta T cell differentiation	P	The process in which a relatively unspecialized hemopoietic cell acquires specialized features of a gamma-delta T cell. A gamma-delta T cell is a T cell that expresses a gamma-delta T cell receptor complex.
42493	response to drug	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a drug stimulus. A drug is a substance used in the diagnosis, treatment or prevention of a disease.
42494	detection of bacterial lipoprotein	P	The series of events in which a bacterial lipoprotein stimulus is received by a cell and converted into a molecular signal. Bacterial lipoproteins are lipoproteins characterized by the presence of conserved sequence motifs called pathogen-associated molecular patterns (PAMPs).
42495	detection of triacyl bacterial lipopeptide	P	The series of events in which a triacylated bacterial lipoprotein stimulus is received by a cell and converted into a molecular signal. Triacylated bacterial lipoproteins are lipopeptides of bacterial origin containing a nonprotein moiety consisting of three acyl groups.
42496	detection of diacyl bacterial lipopeptide	P	The series of events in which a diacylated bacterial lipopeptide stimulus is received by a cell and converted into a molecular signal. Diacylated bacterial lipoproteins are lipopeptides of bacterial origin containing a nonprotein moiety consisting of two acyl groups.
42497	triacyl lipopeptide binding	F	Interacting selectively and non-covalently with a lipopeptide containing a nonprotein moiety consisting of three acyl groups.
42498	diacyl lipopeptide binding	F	Interacting selectively and non-covalently with a lipopeptide containing a nonprotein moiety consisting of two acyl groups.
42500	aspartic endopeptidase activity, intramembrane cleaving	F	Catalysis of the hydrolysis of nonterminal peptide bonds in a polypeptide chain, occurring within a membrane.
42501	serine phosphorylation of STAT protein	P	The process of introducing a phosphate group to a serine residue of a STAT (Signal Transducer and Activator of Transcription) protein.
42502	tyrosine phosphorylation of Stat2 protein	P	The process of introducing a phosphate group to a tyrosine residue of a Stat2 protein.
42503	tyrosine phosphorylation of Stat3 protein	P	The process of introducing a phosphate group to a tyrosine residue of a Stat3 protein.
42504	tyrosine phosphorylation of Stat4 protein	P	The process of introducing a phosphate group to a tyrosine residue of a Stat4 protein.
42505	tyrosine phosphorylation of Stat6 protein	P	The process of introducing a phosphate group to a tyrosine residue of a Stat6 protein.
42506	tyrosine phosphorylation of Stat5 protein	P	The process of introducing a phosphate group to a tyrosine residue of a Stat5 protein.
42507	tyrosine phosphorylation of Stat7 protein	P	The process of introducing a phosphate group to a tyrosine residue of a Stat7 protein.
42508	tyrosine phosphorylation of Stat1 protein	P	The process of introducing a phosphate group to a tyrosine residue of a Stat1 protein.
42509	regulation of tyrosine phosphorylation of STAT protein	P	Any process that modulates the frequency, rate or extent of the introduction of a phosphate group to a tyrosine residue of a STAT (Signal Transducer and Activator of Transcription) protein.
42510	regulation of tyrosine phosphorylation of Stat1 protein	P	Any process that modulates the frequency, rate or extent of introducing a phosphate group to a tyrosine residue of a Stat1 protein.
42511	positive regulation of tyrosine phosphorylation of Stat1 protein	P	Any process that activates or increases the frequency, rate or extent of the introduction of a phosphate group to a tyrosine residue of a Stat1 protein.
42512	negative regulation of tyrosine phosphorylation of Stat1 protein	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the introduction of a phosphate group to a tyrosine residue of a Stat1 protein.
42513	regulation of tyrosine phosphorylation of Stat2 protein	P	Any process that modulates the frequency, rate or extent of introducing a phosphate group to a tyrosine residue of a Stat2 protein.
42514	negative regulation of tyrosine phosphorylation of Stat2 protein	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the introduction of a phosphate group to a tyrosine residue of a Stat2 protein.
42515	positive regulation of tyrosine phosphorylation of Stat2 protein	P	Any process that activates or increases the frequency, rate or extent of the introduction of a phosphate group to a tyrosine residue of a Stat2 protein.
42516	regulation of tyrosine phosphorylation of Stat3 protein	P	Any process that modulates the frequency, rate or extent of introducing a phosphate group to a tyrosine residue of a Stat3 protein.
42517	positive regulation of tyrosine phosphorylation of Stat3 protein	P	Any process that activates or increases the frequency, rate or extent of the introduction of a phosphate group to a tyrosine residue of a Stat3 protein.
42518	negative regulation of tyrosine phosphorylation of Stat3 protein	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the introduction of a phosphate group to a tyrosine residue of a Stat3 protein.
42519	regulation of tyrosine phosphorylation of Stat4 protein	P	Any process that modulates the frequency, rate or extent of introducing a phosphate group to a tyrosine residue of a Stat4 protein.
42520	positive regulation of tyrosine phosphorylation of Stat4 protein	P	Any process that activates or increases the frequency, rate or extent of the introduction of a phosphate group to a tyrosine residue of a Stat4 protein.
42521	negative regulation of tyrosine phosphorylation of Stat4 protein	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the introduction of a phosphate group to a tyrosine residue of a Stat4 protein.
42522	regulation of tyrosine phosphorylation of Stat5 protein	P	Any process that modulates the frequency, rate or extent of introducing a phosphate group to a tyrosine residue of a Stat5 protein.
42523	positive regulation of tyrosine phosphorylation of Stat5 protein	P	Any process that activates or increases the frequency, rate or extent of the introduction of a phosphate group to a tyrosine residue of a Stat5 protein.
42524	negative regulation of tyrosine phosphorylation of Stat5 protein	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the introduction of a phosphate group to a tyrosine residue of a Stat5 protein.
42525	regulation of tyrosine phosphorylation of Stat6 protein	P	Any process that modulates the frequency, rate or extent of introducing a phosphate group to a tyrosine residue of a Stat6 protein.
42526	positive regulation of tyrosine phosphorylation of Stat6 protein	P	Any process that activates or increases the frequency, rate or extent of the introduction of a phosphate group to a tyrosine residue of a Stat6 protein.
42527	negative regulation of tyrosine phosphorylation of Stat6 protein	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the introduction of a phosphate group to a tyrosine residue of a Stat6 protein.
42528	regulation of tyrosine phosphorylation of Stat7 protein	P	Any process that modulates the frequency, rate or extent of introducing a phosphate group to a tyrosine residue of a Stat7 protein.
42529	positive regulation of tyrosine phosphorylation of Stat7 protein	P	Any process that activates or increases the frequency, rate or extent of the introduction of a phosphate group to a tyrosine residue of a Stat7 protein.
42530	negative regulation of tyrosine phosphorylation of Stat7 protein	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the introduction of a phosphate group to a tyrosine residue of a Stat7 protein.
42531	positive regulation of tyrosine phosphorylation of STAT protein	P	Any process that activates or increases the frequency, rate or extent of the introduction of a phosphate group to a tyrosine residue of a STAT (Signal Transducer and Activator of Transcription) protein.
42532	negative regulation of tyrosine phosphorylation of STAT protein	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the introduction of a phosphate group to a tyrosine residue of a STAT (Signal Transducer and Activator of Transcription) protein.
42533	tumor necrosis factor biosynthetic process	P	The chemical reactions and pathways resulting in the formation of tumor necrosis factor, an inflammatory cytokine produced by macrophages/monocytes during acute inflammation and which is responsible for a diverse range of signaling events within cells, leading to necrosis or apoptosis.
42534	regulation of tumor necrosis factor biosynthetic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of tumor necrosis factor, an inflammatory cytokine produced by macrophages/monocytes during acute inflammation and which is responsible for a diverse range of signaling events within cells, leading to necrosis or apoptosis.
42535	positive regulation of tumor necrosis factor biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of tumor necrosis factor, an inflammatory cytokine produced by macrophages/monocytes during acute inflammation and which is responsible for a diverse range of signaling events within cells, leading to necrosis or apoptosis.
42536	negative regulation of tumor necrosis factor biosynthetic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of tumor necrosis factor, an inflammatory cytokine produced by macrophages/monocytes during acute inflammation and which is responsible for a diverse range of signaling events within cells, leading to necrosis or apoptosis.
42537	benzene-containing compound metabolic process	P	The chemical reactions and pathways involving benzene, C6H6, a volatile, very inflammable liquid, contained in the naphtha produced by the destructive distillation of coal, from which it is separated by fractional distillation, or any of its derivatives.
42538	hyperosmotic salinity response	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, an increase in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment.
42539	hypotonic salinity response	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment.
42540	hemoglobin catabolic process	P	The chemical reactions and pathways resulting in the breakdown of hemoglobin, an oxygen carrying, conjugated protein containing four heme groups and globin; especially, the proteolytic cleavage of hemoglobin to yield free heme, peptides, and amino acids.
42541	hemoglobin biosynthetic process	P	The chemical reactions and pathways resulting in the formation of hemoglobin, an oxygen carrying, conjugated protein containing four heme groups and globin.
42542	response to hydrogen peroxide	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrogen peroxide (H2O2) stimulus.
42543	protein N-linked glycosylation via arginine	P	The glycosylation of protein via peptidyl-arginine, omega-N-glycosyl-L-arginine.
42544	melibiose biosynthetic process	P	The chemical reactions and pathways resulting in the formation of melibiose, the disaccharide 6-O-alpha-D-galactopyranosyl-D-glucose.
42545	cell wall modification	P	The series of events leading to chemical and structural alterations of an existing cell wall that can result in loosening, increased extensibility or disassembly.
42546	cell wall biogenesis	P	A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cell wall. Includes biosynthesis of constituent macromolecules, such as proteins and polysaccharides, and those macromolecular modifications that are involved in synthesis or assembly of the cellular component. A cell wall is the rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal and most prokaryotic cells, maintaining their shape and protecting them from osmotic lysis.
42547	cell wall modification involved in multidimensional cell growth	P	The series of events resulting in chemical or structural changes to existing cell walls and contribute to multidimensional cell growth.
42548	regulation of photosynthesis, light reaction	P	Any process that modulates the frequency, rate or extent of the light-dependent reaction of photosynthesis.
42549	photosystem II stabilization	P	The stabilization of the photosystem II protein complex, resulting from the phosphorylation of its structural protein subunits, in a cell actively involved in photosynthesis.
42550	photosystem I stabilization	P	The stabilization of the photosystem I protein complex, resulting from the phosphorylation of its structural protein subunits, in a cell actively involved in photosynthesis.
42551	neuron maturation	P	A developmental process, independent of morphogenetic (shape) change, that is required for a neuron to attain its fully functional state.
42552	myelination	P	The process in which myelin sheaths are formed and maintained around neurons. Oligodendrocytes in the brain and spinal cord and Schwann cells in the peripheral nervous system wrap axons with compact layers of their plasma membrane. Adjacent myelin segments are separated by a non-myelinated stretch of axon called a node of Ranvier.
42554	superoxide anion generation	P	The enzymatic generation of superoxide, the superoxide anion O2- (superoxide free radical), or any compound containing this species, by a cell in response to environmental stress, thereby mediating the activation of various stress-inducible signaling pathways.
42555	MCM complex	C	A hexameric protein complex required for the initiation and regulation of DNA replication.
42556	eukaryotic elongation factor-2 kinase regulator activity	F	Modulates the activity of the enzyme eukaryotic elongation factor-2 kinase.
42557	eukaryotic elongation factor-2 kinase activator activity	F	Binds to and increases the activity of the enzyme eukaryotic elongation factor-2 kinase.
42558	pteridine-containing compound metabolic process	P	The chemical reactions and pathways involving any compound containing pteridine (pyrazino(2,3-dipyrimidine)), e.g. pteroic acid, xanthopterin and folic acid.
42559	pteridine-containing compound biosynthetic process	P	The chemical reactions and pathways resulting in the formation of any compound containing pteridine (pyrazino(2,3-dipyrimidine)), e.g. pteroic acid, xanthopterin and folic acid.
42560	pteridine-containing compound catabolic process	P	The chemical reactions and pathways resulting in the breakdown of any compound containing pteridine (pyrazino(2,3-dipyrimidine)), e.g. pteroic acid, xanthopterin and folic acid.
42561	alpha-amyrin synthase activity	F	Catalysis of the reaction: (S)-2,3-epoxysqualene = alpha-amyrin. This reaction is a cyclization and rearrangement of (S)-2,3-epoxysqualene (2,3-oxidosqualene) into alpha-amyrin.
42562	hormone binding	F	Interacting selectively and non-covalently with any hormone, naturally occurring substances secreted by specialized cells that affect the metabolism or behavior of other cells possessing functional receptors for the hormone.
42563	importin alpha-subunit nuclear export complex	C	A protein complex which usually consists of three components, e.g. in Xenopus, the importin alpha-subunit/CAS/Ran, and which functions to shuttle the importin alpha-subunit out of the nucleus through the nuclear pore.
42564	NLS-dependent protein nuclear import complex	C	A protein complex which usually consists of three components, e.g. in Xenopus, the importin alpha and beta-subunits and any protein which has a nuclear localization sequence (NLS). The complex acts to import proteins with an NLS into the nucleus through a nuclear pore.
42565	RNA nuclear export complex	C	A complex which usually consists of three components, e.g. in Xenopus and yeast, the export receptor CRM1 (also known as exportin 1), the Ran protein and any RNA with a nuclear export sequence (NES). The complex acts to export RNA molecules with a NES from the nucleus through a nuclear pore.
42566	hydrogenosome	C	A spherical, membrane-bounded organelle found in some anaerobic protozoa, which participates in ATP and molecular hydrogen formation.
42567	insulin-like growth factor ternary complex	C	A complex of three proteins, which in animals is approximately 150kDa and consists of the insulin-like growth factor (IGF), the insulin-like growth factor binding protein-3 (IGFBP-3), or -5 (IGFBP-5) and an acid-labile subunit (ALS). The complex plays a role in growth and development.
42568	insulin-like growth factor binary complex	C	A complex of two proteins, which in animals is 50kDa and consists of the insulin-like growth factor (IGF) and one of the insulin-like growth factor binding protein-1 (IGFBP-1), -2 (IGFBP-2), -4 (IGFBP-4) and -6 (IGFBP-6). The complex plays a role in growth and development.
42571	immunoglobulin complex, circulating	C	An immunoglobulin complex that is secreted into extracellular space and found in mucosal areas or other tissues or circulating in the blood or lymph. In its canonical form, a circulating immunoglobulin complex is composed of two identical heavy chains and two identical light chains, held together by disulfide bonds. Some forms of are polymers of the basic structure and contain additional components such as J-chain and the secretory component.
42572	retinol metabolic process	P	The chemical reactions and pathways involving retinol, one of the three compounds that makes up vitamin A.
42573	retinoic acid metabolic process	P	The chemical reactions and pathways involving retinoic acid, one of the three components that makes up vitamin A.
42574	retinal metabolic process	P	The chemical reactions and pathways involving retinal, a compound that plays an important role in the visual process in most vertebrates. In the retina, retinal combines with opsins to form visual pigments. Retinal is one of the forms of vitamin A.
42575	DNA polymerase complex	C	A protein complex that possesses DNA polymerase activity and is involved in template directed synthesis of DNA.
42577	lipid phosphatase activity	F	Catalysis of the reaction: a phospholipid + H2O = a lipid + phosphate.
42578	phosphoric ester hydrolase activity	F	Catalysis of the reaction: RPO-R' + H2O = RPOOH + R'H. This reaction is the hydrolysis of any phosphoric ester bond, any ester formed from orthophosphoric acid, O=P(OH)3.
42579	microbody	C	Cytoplasmic organelles, spherical or oval in shape, that are bounded by a single membrane and contain oxidative enzymes, especially those utilizing hydrogen peroxide (H2O2).
42580	mannosome	C	A specialised tubular organelle, assembled in hexagonal bundles within an external membrane. Mannosomes are specific to molluscs and are thought to be involved in a general stress reaction.
42581	specific granule	C	Granule with a membranous, tubular internal structure, found primarily in mature neutrophil cells. Most are released into the extracellular fluid. Specific granules contain lactoferrin, lysozyme, vitamin B12 binding protein and elastase.
42582	azurophil granule	C	Primary lysosomal granule found in neutrophil granulocytes. Contains a wide range of hydrolytic enzymes and is released into the extracellular fluid.
42583	chromaffin granule	C	Specialized secretory vesicle found in the cells of adrenal glands and various other organs, which is concerned with the synthesis, storage, metabolism, and secretion of epinephrine and norepinephrine.
42584	chromaffin granule membrane	C	The lipid bilayer surrounding a chromaffin granule, a specialized secretory vesicle found in the cells of adrenal glands and various other organs, which is concerned with the synthesis, storage, metabolism, and secretion of epinephrine and norepinephrine.
42585	germinal vesicle	C	The enlarged, fluid filled nucleus of a primary oocyte, the development of which is suspended in prophase I of the first meiotic division between embryohood and sexual maturity.
42586	peptide deformylase activity	F	Catalysis of the reaction: formyl-L-methionyl peptide + H2O = formate + methionyl peptide.
42587	glycogen granule	C	Cytoplasmic bead-like structures of animal cells, visible by electron microscope. Each granule is a functional unit with the biosynthesis and catabolism of glycogen being catalyzed by enzymes bound to the granule surface.
42588	zymogen granule	C	A membrane-bounded, cytoplasmic secretory granule found in enzyme-secreting cells and visible by light microscopy. Contain zymogen, an inactive enzyme precursor, often of a digestive enzyme.
42589	zymogen granule membrane	C	The lipid bilayer surrounding a zymogen granule.
42590	antigen processing and presentation of exogenous peptide antigen via MHC class I	P	The process in which an antigen-presenting cell expresses a peptide antigen of exogenous origin on its cell surface in association with an MHC class I protein complex. The peptide antigen is typically, but not always, processed from a whole protein. Class I here refers to classical class I molecules.
42592	homeostatic process	P	Any biological process involved in the maintenance of an internal steady state.
42593	glucose homeostasis	P	Any process involved in the maintenance of an internal steady state of glucose within an organism or cell.
42594	response to starvation	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a starvation stimulus, deprivation of nourishment.
42595	behavioral response to starvation	P	Any process that results in a change in the behavior of an organism as a result of deprivation of nourishment.
42596	fear response	P	The response of an organism to a perceived external threat.
42597	periplasmic space	C	The region between the inner (cytoplasmic) and outer membrane (Gram-negative Bacteria) or cytoplasmic membrane and cell wall (Fungi and Gram-positive Bacteria).
42599	lamellar body	C	A membrane-bounded organelle, specialized for the storage and secretion of various substances (surfactant phospholipids, glycoproteins and acid phosphates) which are arranged in the form of tightly packed, concentric, membrane sheets or lamellae. Has some similar properties to, but is distinct from, a lysosome.
42600	chorion	C	A protective, noncellular membrane that surrounds the eggs of various animals including insects and fish.
42601	endospore-forming forespore	C	Portion of the cell formed during the process of bacterial sporulation that will ultimately become the core of the endospore. An endospore is a type of dormant cell that is resistant to adverse conditions.
42602	riboflavin reductase (NADPH) activity	F	Catalysis of the reaction: reduced riboflavin + NADP+ = riboflavin + NADPH + 2 H+.
42603	capsule	C	A protective structure surrounding some fungi and bacteria, attached externally to the cell wall and composed primarily of polysaccharides. Capsules are highly organized structures that adhere strongly to cells and cannot be easily removed. Capsules play important roles in pathogenicity, preventing phagocytosis by other cells, adherance, and resistance to dessication.
42605	peptide antigen binding	F	Interacting selectively and non-covalently with an antigen peptide.
42608	T cell receptor binding	F	Interacting selectively and non-covalently with a T cell receptor, the antigen-recognizing receptor on the surface of T cells.
42609	CD4 receptor binding	F	Interacting selectively and non-covalently with a CD4, a receptor found on the surface of T cells, monocytes and macrophages.
42610	CD8 receptor binding	F	Interacting selectively and non-covalently with a CD8, a receptor found on the surface of thymocytes and cytotoxic and suppressor T-lymphocytes.
42611	MHC protein complex	C	A transmembrane protein complex composed of an MHC alpha chain and, in most cases, either an MHC class II beta chain or an invariant beta2-microglobin chain, and with or without a bound peptide, lipid, or polysaccharide antigen.
42612	MHC class I protein complex	C	A transmembrane protein complex composed of a MHC class I alpha chain and an invariant beta2-microglobin chain, and with or without a bound peptide antigen. Class I here refers to classical class I molecules.
42613	MHC class II protein complex	C	A transmembrane protein complex composed of an MHC class II alpha and MHC class II beta chain, and with or without a bound peptide or polysaccharide antigen.
42614	CD70 receptor binding	F	Interacting selectively and non-covalently with a CD70, a receptor found on the surface of most activated B cells and some activated T cells.
42615	CD154 receptor binding	F	Interacting selectively and non-covalently with CD154, a receptor found on the surface of some activated lymphocytes.
42616	paclitaxel metabolic process	P	The chemical reactions and pathways involving paclitaxel, an alkaloid compound used as an anticancer treatment.
42617	paclitaxel biosynthetic process	P	The chemical reactions and pathways resulting in the formation of paclitaxel, an alkaloid compound used as an anticancer treatment.
42618	poly-hydroxybutyrate metabolic process	P	The chemical reactions and pathways involving poly-hydroxybutyrate (PHB), a polymer of beta-hydroxybutyrate and a common storage material of prokaryotic cells.
42619	poly-hydroxybutyrate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of poly-hydroxybutyrate (PHB), a polymer of beta-hydroxybutyrate and a common storage material of prokaryotic cells.
42620	poly(3-hydroxyalkanoate) metabolic process	P	The chemical reactions and pathways involving poly(3-hydroxyalkanoates), polyesters of 3-hydroxyacids produced as intracellular granules by a large variety of bacteria.
42621	poly(3-hydroxyalkanoate) biosynthetic process	P	The chemical reactions and pathways resulting in the formation of poly(3-hydroxyalkanoates), polyesters of 3-hydroxyacids produced as intracellular granules by a large variety of bacteria.
42622	photoreceptor outer segment membrane	C	The membrane surrounding the outer segment of a vertebrate photoreceptor.
42623	ATPase activity, coupled	F	Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction directly drives some other reaction, for example ion transport across a membrane.
42624	ATPase activity, uncoupled	F	Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction is not directly coupled to any other reaction.
42625	ATPase coupled ion transmembrane transporter activity	F	Catalysis of the transfer of an ion from one side of a membrane to the other, driven by the reaction: ATP + H2O = ADP + phosphate.
42626	ATPase activity, coupled to transmembrane movement of substances	F	Catalysis of the reaction: ATP + H2O = ADP + phosphate, to directly drive the active transport of a substance across a membrane.
42627	chylomicron	C	A large lipoprotein particle (diameter 75-1200 nm) composed of a central core of triglycerides and cholesterol surrounded by a protein-phospholipid coating. The proteins include one molecule of apolipoprotein B-48 and may include a variety of apolipoproteins, including APOAs, APOCs and APOE. Chylomicrons are found in blood or lymph and carry lipids from the intestines into other body tissues.
42628	mating plug formation	P	The deposition of a plug of sperm or other gelatinous material into the opening of the vulva by a male at the termination of copulation. Probably acts to prevent subsequent matings by other males.
42629	mast cell granule	C	Coarse, bluish-black staining cytoplasmic granules, bounded by a plasma membrane and found in mast cells and basophils. Contents include histamine, heparin, chondroitin sulfates, chymase and tryptase.
42630	behavioral response to water deprivation	P	Any process that results in a change in the behavior of an organism as a result of deprivation of water.
42631	cellular response to water deprivation	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of water.
42632	cholesterol homeostasis	P	Any process involved in the maintenance of an internal steady state of cholesterol within an organism or cell.
42633	hair cycle	P	The cyclical phases of growth (anagen), regression (catagen), quiescence (telogen), and shedding (exogen) in the life of a hair; one of the collection or mass of filaments growing from the skin of an animal, and forming a covering for a part of the head or for any part or the whole of the body.
42634	regulation of hair cycle	P	Any process that modulates the frequency, rate or extent of the cyclical phases of growth (anagen), regression (catagen), quiescence (telogen), and shedding (exogen) in the life of a hair.
42635	positive regulation of hair cycle	P	Any process that activates or increases the frequency, rate or extent of the cyclical phases of growth (anagen), regression (catagen), quiescence (telogen), and shedding (exogen) in the life of a hair.
42636	negative regulation of hair cycle	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the cyclical phases of growth (anagen), regression (catagen), quiescence (telogen), and shedding (exogen) in the life of a hair.
42637	catagen	P	The regression phase of the hair cycle during which cell proliferation ceases, the hair follicle shortens, and an anchored club hair is produced.
42638	exogen	P	The shedding phase of the hair cycle.
42639	telogen	P	The resting phase of hair cycle.
42640	anagen	P	The growth phase of the hair cycle. Lasts, for example, about 3 to 6 years for human scalp hair.
42641	actomyosin	C	Any complex of actin, myosin, and accessory proteins.
42642	actomyosin, myosin complex part	C	The myosin part of any complex of actin, myosin, and accessory proteins.
42643	actomyosin, actin portion	C	The actin part of any complex of actin, myosin, and accessory proteins.
42644	chloroplast nucleoid	C	The region of a chloroplast to which the DNA is confined.
42645	mitochondrial nucleoid	C	The region of a mitochondrion to which the DNA is confined.
42646	plastid nucleoid	C	The region of a plastid to which the DNA is confined.
42647	proplastid nucleoid	C	The region of a proplastid to which the DNA is confined.
42648	chloroplast chromosome	C	A circular DNA molecule containing chloroplast encoded genes.
42649	prothylakoid	C	Underdeveloped thylakoids found in etioplasts, lacking competent photosynthetic membranes. Rapidly develop into mature thylakoids in the presence of light.
42650	prothylakoid membrane	C	The membrane of prothylakoids, underdeveloped thylakoids found in etioplasts, lacking competent photosynthetic membranes.
42651	thylakoid membrane	C	The pigmented membrane of any thylakoid.
42652	mitochondrial respiratory chain complex I, peripheral segment	C	The peripheral segment of respiratory chain complex I located in the mitochondrion. Respiratory chain complex I is an enzyme of the respiratory chain, consisting of at least 34 polypeptide chains. The electrons of NADH enter the chain at this complex. The complete complex is L-shaped, with a horizontal arm lying in the membrane and a vertical arm that projects into the matrix.
42653	mitochondrial respiratory chain complex I, membrane segment	C	The mitochondrial membrane segment of respiratory chain complex I. Respiratory chain complex I is an enzyme of the respiratory chain, consisting of at least 34 polypeptide chains. The electrons of NADH enter the chain at this complex. The complete complex is L-shaped, with a horizontal arm lying in the membrane and a vertical arm that projects into the matrix.
42654	ecdysis-triggering hormone receptor activity	F	Combining with ecdysis-triggering hormone to initiate a change in cell activity.
42655	activation of JNKKK activity	P	The initiation of the activity of the inactive enzyme JUN kinase kinase kinase (JNKKK) activity.
42656	JUN kinase kinase kinase kinase activity	F	Catalysis of the phosphorylation and activation of JUN kinase kinase kinases (JNKKKs).
42657	MHC class II protein binding, via lateral surface	F	Interacting selectively and non-covalently with the lateral surface of major histocompatibility complex class II molecules.
42658	MHC class II protein binding, via antigen binding groove	F	Interacting selectively and non-covalently with the antigen binding groove of major histocompatibility complex class II molecules.
42659	regulation of cell fate specification	P	Any process that mediates the adoption of a specific fate by a cell.
42660	positive regulation of cell fate specification	P	Any process that activates or enables a cell to adopt a specific fate.
42661	regulation of mesodermal cell fate specification	P	Any process that modulates the frequency, rate or extent of mesoderm cell fate specification.
42662	negative regulation of mesodermal cell fate specification	P	Any process that stops, prevents, or reduces the frequency, rate or extent of mesoderm cell fate specification.
42663	regulation of endodermal cell fate specification	P	Any process that mediates the specification of a cell into an endoderm cell.
42664	negative regulation of endodermal cell fate specification	P	Any process that restricts, stops or prevents a cell from specifying into an endoderm cell.
42665	regulation of ectodermal cell fate specification	P	Any process that mediates the specification of a cell into an ectoderm cell.
42666	negative regulation of ectodermal cell fate specification	P	Any process that restricts, stops or prevents a cell from specifying into an ectoderm cell.
42667	auditory receptor cell fate specification	P	The process in which a cell becomes capable of differentiating autonomously into an auditory hair cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.
42668	auditory receptor cell fate determination	P	The process in which a cell becomes capable of differentiating autonomously into an auditory hair cell regardless of its environment; upon determination, the cell fate cannot be reversed.
42669	regulation of auditory receptor cell fate specification	P	Any process that mediates the specification of a cell into an auditory hair cell.
42670	retinal cone cell differentiation	P	The process in which a relatively unspecialized cell acquires the specialized features of a retinal cone cell.
42671	retinal cone cell fate determination	P	The process in which a cell becomes capable of differentiating autonomously into a retinal cone cell regardless of its environment; upon determination, the cell fate cannot be reversed.
42672	retinal cone cell fate specification	P	The process in which a cell becomes capable of differentiating autonomously into a retinal cone cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.
42673	regulation of retinal cone cell fate specification	P	Any process that mediates the specification of a cell into a retinal cone cell.
42675	compound eye cone cell differentiation	P	The process in which a relatively unspecialized cell acquires the specialized features of a compound eye cone cell, a cone-shaped cell, that focuses light in a compound eye.
42676	compound eye cone cell fate commitment	P	The process in which the cone cells of the compound eye, the lens-secreting cells in the ommatidia, adopt pathways of differentiation that lead to the establishment of their distinct cell type.
42679	compound eye cone cell fate specification	P	The process in which a cell becomes capable of differentiating autonomously into a compound eye cone cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.
42680	compound eye cone cell fate determination	P	The process in which a cell becomes capable of differentiating autonomously into a compound eye cone cell regardless of its environment; upon determination, the cell fate cannot be reversed.
42682	regulation of compound eye cone cell fate specification	P	Any process that mediates the specification of a cell into a compound eye cone cell.
42683	negative regulation of compound eye cone cell fate specification	P	Any process that restricts, stops or prevents a cell from specifying into a compound eye cone cell.
42684	cardioblast cell fate commitment	P	The process in which a cell becomes committed to becoming a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.
42685	cardioblast cell fate specification	P	The process in which a cell becomes capable of differentiating autonomously into a cardioblast cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.
42686	regulation of cardioblast cell fate specification	P	Any process that mediates the specification of a cell into a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.
42688	crystal cell differentiation	P	The process in which a hemocyte precursor cell acquires the characteristics of a crystal cell, a class of cells that contain crystalline inclusions and are involved in the melanization of pathogenic material in the hemolymph.
42689	regulation of crystal cell differentiation	P	Any process that modulates the frequency, rate or extent of crystal cell differentiation.
42690	negative regulation of crystal cell differentiation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of crystal cell differentiation.
42691	positive regulation of crystal cell differentiation	P	Any process that activates or increases the frequency, rate or extent of crystal cell differentiation.
42692	muscle cell differentiation	P	The process in which a relatively unspecialized cell acquires specialized features of a muscle cell.
42693	muscle cell fate commitment	P	The process in which the cellular identity of muscle cells is acquired and determined.
42694	muscle cell fate specification	P	The process in which a cell becomes capable of differentiating autonomously into a muscle cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.
42695	thelarche	P	The beginning of development of the breasts in the female.
42696	menarche	P	The beginning of the menstrual cycle; the first menstrual cycle in an individual.
42697	menopause	P	Cessation of menstruation, occurring in (e.g.) the human female usually around the age of 50.
42698	ovulation cycle	P	The type of sexual cycle seen in females, often with physiologic changes in the endometrium that recur at regular intervals during the reproductive years.
42699	follicle-stimulating hormone signaling pathway	P	The series of molecular signals mediated by follicle-stimulating hormone.
42700	luteinizing hormone signaling pathway	P	The series of molecular signals mediated by luteinizing hormone.
42701	progesterone secretion	P	The regulated release of progesterone, a steroid hormone, by the corpus luteum of the ovary and by the placenta.
42702	uterine wall growth	P	The regrowth of the endometrium and blood vessels in the uterus following menstruation, resulting from a rise in progesterone levels.
42703	menstruation	P	The cyclic, physiologic discharge through the vagina of blood and endometrial tissues from the nonpregnant uterus.
42704	uterine wall breakdown	P	The sloughing of the endometrium and blood vessels during menstruation that results from a drop in progesterone levels.
42705	ocellus photoreceptor cell differentiation	P	The process in which a relatively unspecialized cell acquires specialized features of a photoreceptor cell found in the ocellus.
42706	eye photoreceptor cell fate commitment	P	The process in which the developmental fate of a cell becomes restricted such that it will develop into an eye photoreceptor cell. A photoreceptor cell is a cell that responds to incident electromagnetic radiation. Different classes of photoreceptor have different spectral sensitivities and express different photosensitive pigments.
42707	ocellus photoreceptor cell fate commitment	P	The process in which the developmental fate of a cell becomes restricted such that it will develop into photoreceptor cell in the ocellus. A photoreceptor cell is a cell that responds to incident electromagnetic radiation. Different classes of photoreceptor have different spectral sensitivities and express different photosensitive pigments.
42709	succinate-CoA ligase complex	C	A heterodimeric enzyme complex, usually composed of an alpha and beta chain. Functions in the TCA cycle, hydrolyzing succinyl-CoA into succinate and CoA, thereby forming ATP or GTP.
42710	biofilm formation	P	A process in which planktonically growing microorganisms grow at a liquid-air interface or on a solid substrate under the flow of a liquid and produce extracellular polymers that facilitate matrix formation, resulting in a change in the organisms' growth rate and gene transcription.
42711	maternal behavior	P	Female behaviors associated with the care and rearing of offspring.
42712	paternal behavior	P	Male behaviors associated with the care and rearing offspring.
42713	sperm ejaculation	P	The expulsion of seminal fluid, thick white fluid containing spermatozoa, from the male genital tract.
42714	dosage compensation complex assembly	P	The aggregation, arrangement and bonding together of proteins on DNA or RNA to form the complex that mediates dosage compensation on one or more X chromosomes.
42715	dosage compensation complex assembly involved in dosage compensation by hypoactivation of X chromosome	P	The aggregation, arrangement and bonding together of proteins on DNA to form the complex that mediates dosage compensation on both X chromosomes in the monogametic sex, ultimately resulting in a two-fold reduction in transcription from these chromosomes. An example of this process is found in Caenorhabditis elegans.
42716	plasma membrane-derived chromatophore	C	A pigment-bearing structure that is derived from the cytoplasmic membrane, sometimes consisting of simple invaginations and sometimes a complete vesicle. This component is found in certain photosynthetic bacteria and cyanobacteria.
42717	plasma membrane-derived chromatophore membrane	C	The lipid bilayer associated with a plasma membrane-derived chromatophore; surrounds chromatophores that form complete vesicles.
42718	yolk granule	C	Discrete structures that partition the water-insoluble portion of the yolk of oocytes and ova, which may or may not be membrane enclosed.
42719	mitochondrial intermembrane space protein transporter complex	C	Soluble complex of the mitochondrial intermembrane space composed of various combinations of small Tim proteins; acts as a protein transporter to guide proteins to the Tim22 complex for insertion into the mitochondrial inner membrane.
42720	mitochondrial inner membrane peptidase complex	C	Protease complex of the mitochondrial inner membrane, consisting of at least two subunits, involved in processing of both nuclear- and mitochondrially-encoded proteins targeted to the intermembrane space.
42721	mitochondrial inner membrane protein insertion complex	C	A multi-subunit complex embedded in the mitochondrial inner membrane that mediates insertion of carrier proteins into the inner membrane.
42722	alpha-beta T cell activation by superantigen	P	The change in morphology and behavior of alpha-beta T cells resulting from exposure to a superantigen, a microbial antigen with an extremely potent activating effect on T cells that bear a specific variable region.
42723	thiamine-containing compound metabolic process	P	The chemical reactions and pathways involving thiamine (vitamin B1), and compounds derived from it.
42724	thiamine-containing compound biosynthetic process	P	The chemical reactions and pathways resulting in the formation of thiamine (vitamin B1), and related compounds.
42725	thiamine-containing compound catabolic process	P	The chemical reactions and pathways resulting in the breakdown of thiamine (vitamin B1), and compounds derived from it.
42726	flavin-containing compound metabolic process	P	The chemical reactions and pathways involving a flavin, any derivative of the dimethylisoalloxazine (7,8-dimethylbenzo[g]pteridine-2,4(3H,10H)-dione) skeleton, with a substituent on the 10 position.
42727	flavin-containing compound biosynthetic process	P	The chemical reactions and pathways resulting in the formation of a flavin, any derivative of the dimethylisoalloxazine (7,8-dimethylbenzo[g]pteridine-2,4(3H,10H)-dione) skeleton, with a substituent on the 10 position.
42728	flavin-containing compound catabolic process	P	The chemical reactions and pathways resulting in the breakdown of a flavin, any derivative of the dimethylisoalloxazine (7,8-dimethylbenzo[g]pteridine-2,4(3H,10H)-dione) skeleton, with a substituent on the 10 position.
42729	DASH complex	C	A large protein complex, containing around 8-10 subunits in yeast, including Duo1p, Dam1p, Dad1p and Ask1p. The complex forms part of the kinetochore, associates with microtubules when the kinetochore attaches to the spindle, and plays a role in spindle attachment, chromosome segregation and spindle stability.
42730	fibrinolysis	P	A process that solubilizes fibrin in the bloodstream of a multicellular organism, chiefly by the proteolytic action of plasmin.
42731	PH domain binding	F	Interacting selectively and non-covalently with a PH domain (pleckstrin homology) of a protein, a domain of about 100 residues that occurs in a wide range of proteins involved in intracellular signaling or as constituents of the cytoskeleton.
42732	D-xylose metabolic process	P	The chemical reactions and pathways involving D-xylose, a naturally occurring plant polysaccharide.
42733	embryonic digit morphogenesis	P	The process, occurring in the embryo, by which the anatomical structures of the digit are generated and organized. A digit is one of the terminal divisions of an appendage, such as a finger or toe.
42734	presynaptic membrane	C	A specialized area of membrane of the axon terminal that faces the plasma membrane of the neuron or muscle fiber with which the axon terminal establishes a synaptic junction; many synaptic junctions exhibit structural presynaptic characteristics, such as conical, electron-dense internal protrusions, that distinguish it from the remainder of the axon plasma membrane.
42735	protein body	C	A membrane-bounded plant organelle found in the developing endosperm, contains storage proteins.
42736	NADH kinase activity	F	Catalysis of the reaction: ATP + NADH = ADP + 2 H(+) + NADPH.
42737	drug catabolic process	P	The chemical reactions and pathways resulting in the breakdown of a drug, a substance used in the diagnosis, treatment or prevention of a disease.
42738	exogenous drug catabolic process	P	The chemical reactions and pathways resulting in the breakdown of a drug that has originated externally to the cell or organism.
42739	endogenous drug catabolic process	P	The chemical reactions and pathways resulting in the breakdown of a drug that has originated internally within the cell or organism.
42740	exogenous antibiotic catabolic process	P	The chemical reactions and pathways resulting in the breakdown of an antibiotic that has originated externally to the cell or organism.
42741	endogenous antibiotic catabolic process	P	The chemical reactions and pathways resulting in the breakdown of an antibiotic that has originated internally within the cell or organism.
42742	defense response to bacterium	P	Reactions triggered in response to the presence of a bacterium that act to protect the cell or organism.
42743	hydrogen peroxide metabolic process	P	The chemical reactions and pathways involving hydrogen peroxide (H2O2), a potentially harmful byproduct of aerobic cellular respiration which can cause damage to DNA.
42744	hydrogen peroxide catabolic process	P	The chemical reactions and pathways resulting in the breakdown of hydrogen peroxide (H2O2).
42745	circadian sleep/wake cycle	P	The cycle from wakefulness through an orderly succession of sleep states and stages that occurs on an approximately 24 hour rhythm.
42746	circadian sleep/wake cycle, wakefulness	P	The part of the circadian sleep/wake cycle where the organism is not asleep.
42747	circadian sleep/wake cycle, REM sleep	P	A stage in the circadian sleep cycle during which dreams occur and the body undergoes marked changes including rapid eye movement, loss of reflexes, and increased pulse rate and brain activity.
42748	circadian sleep/wake cycle, non-REM sleep	P	All sleep stages in the circadian sleep/wake cycle other than REM sleep. These stages are characterized by a slowing of brain waves and other physiological functions.
42749	regulation of circadian sleep/wake cycle	P	Any process that modulates the frequency, rate or extent of the circadian sleep/wake cycle.
42750	hibernation	P	Any process in which an organism enters and maintains a period of dormancy in which to pass the winter. It is characterized by narcosis and by sharp reduction in body temperature and metabolic activity and by a depression of vital signs.
42751	estivation	P	Any process in which an organism enters and maintains a period of dormancy, similar to hibernation, but that occurs during the summer. It insulates against heat to prevent the harmful effects of the season.
42752	regulation of circadian rhythm	P	Any process that modulates the frequency, rate or extent of a circadian rhythm. A circadian rhythm is a biological process in an organism that recurs with a regularity of approximately 24 hours.
42753	positive regulation of circadian rhythm	P	Any process that activates or increases the frequency, rate or extent of a circadian rhythm behavior.
42754	negative regulation of circadian rhythm	P	Any process that stops, prevents, or reduces the frequency, rate or extent of a circadian rhythm behavior.
42755	eating behavior	P	The specific behavior of an organism relating to the intake of food, any substance (usually solid) that can be metabolized by an organism to give energy and build tissue.
42756	drinking behavior	P	The specific behavior of an organism relating to the intake of liquids, especially water.
42757	giant axon	C	Extremely large, unmyelinated axon found in invertebrates. Has high conduction speeds and is usually involved in panic or escape responses.
42758	long-chain fatty acid catabolic process	P	The chemical reactions and pathways resulting in the breakdown of long-chain fatty acids, a fatty acid with a chain length between C13 and C22.
42759	long-chain fatty acid biosynthetic process	P	The chemical reactions and pathways resulting in the formation of long-chain fatty acids, any fatty acid with a chain length between C13 and C22.
42760	very long-chain fatty acid catabolic process	P	The chemical reactions and pathways resulting in the breakdown of a fatty acid which has a chain length greater than C22.
42761	very long-chain fatty acid biosynthetic process	P	The chemical reactions and pathways resulting in the formation of a fatty acid which has a chain length greater than C22.
42762	regulation of sulfur metabolic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving sulfur, the nonmetallic element sulfur or compounds that contain sulfur.
42763	intracellular immature spore	C	A cell or part of the cell that constitutes an early developmental stage of a spore, a small reproductive body that is highly resistant to desiccation and heat and is capable of growing into a new organism, produced especially by certain bacteria, fungi, algae, and nonflowering plants.
42764	ascospore-type prospore	C	An immature spore undergoing development. The spore usually consists of nucleic acid, prospore membrane(s) that encase the nucleic acid, and ultimately a cell wall that covers the membrane(s). This type of spore is observed in ascospore-forming fungi.
42765	GPI-anchor transamidase complex	C	An enzyme complex which in humans and yeast consists of at least five proteins; for example, the complex contains GAA1, GPI8, PIG-S, PIG-U, and PIG-T in human, and Gaa1p, Gab1p, Gpi8p, Gpi16p, and Gpi17p in yeast. Catalyzes the posttranslational attachment of the carboxyl-terminus of a precursor protein to a GPI-anchor.
42766	nucleosome mobilization	P	The movement of nucleosomes along a DNA fragment.
42767	ecdysteroid 22-hydroxylase activity	F	Catalysis of the hydroxylation of an ecdysteroid at carbon position 22.
42768	ecdysteroid 2-hydroxylase activity	F	Catalysis of the hydroxylation of an ecdysteroid at carbon position 2.
42769	DNA damage response, detection of DNA damage	P	The series of events required to receive a stimulus indicating DNA damage has occurred and convert it to a molecular signal.
42770	signal transduction in response to DNA damage	P	A cascade of processes induced by the detection of DNA damage within a cell.
42771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	P	A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage, and ends when the execution phase of apoptosis is triggered.
42772	DNA damage response, signal transduction resulting in transcription	P	A cascade of processes initiated in response to the detection of DNA damage, and resulting in the induction of transcription.
42773	ATP synthesis coupled electron transport	P	The transfer of electrons through a series of electron donors and acceptors, generating energy that is ultimately used for synthesis of ATP.
42774	plasma membrane ATP synthesis coupled electron transport	P	The transfer of electrons through a series of electron donors and acceptors, generating energy that is ultimately used for synthesis of ATP in the plasma membrane.
42775	mitochondrial ATP synthesis coupled electron transport	P	The transfer of electrons through a series of electron donors and acceptors, generating energy that is ultimately used for synthesis of ATP, as it occurs in the mitochondrial inner membrane or chloroplast thylakoid membrane.
42776	mitochondrial ATP synthesis coupled proton transport	P	The transport of protons across a mitochondrial membrane to generate an electrochemical gradient (proton-motive force) that powers ATP synthesis.
42777	plasma membrane ATP synthesis coupled proton transport	P	The transport of protons across the plasma membrane to generate an electrochemical gradient (proton-motive force) that powers ATP synthesis.
42778	tRNA end turnover	P	The process in which the 3'-terminal CCA of a tRNA is removed and restored. This often happens to uncharged tRNA.
42779	tRNA 3'-trailer cleavage	P	Cleavage of the 3'-end of the pre-tRNA as part of the process of generating the mature 3'-end of the tRNA; may involve endonucleolytic or exonucleolytic cleavage, or both.
42780	tRNA 3'-end processing	P	The process in which the 3' end of a pre-tRNA molecule is converted to that of a mature tRNA.
42781	3'-tRNA processing endoribonuclease activity	F	Catalysis of the endonucleolytic cleavage of RNA, removing extra 3' nucleotides from tRNA precursor, generating 3' termini of tRNAs. A 3'-hydroxy group is left at the tRNA terminus and a 5'-phosphoryl group is left at the trailer molecule.
42782	passive evasion of host immune response	P	Any mechanism of immune avoidance that does not directly interfere with the host immune system; for example, some viruses enter a state of latency where their protein production is drastically downregulated, meaning that they are not detected by the host immune system. The host is defined as the larger of the organisms involved in a symbiotic interaction.
42783	active evasion of host immune response	P	Any mechanism of immune avoidance that directly affects the host immune system, e.g. blocking any stage in host MHC class I and II presentation. The host is defined as the larger of the organisms involved in a symbiotic interaction.
42784	active evasion of host immune response via regulation of host complement system	P	Any mechanism of active immune avoidance which works by regulating the host complement system, e.g. by possessing complement receptors which mediate attachment to, then infection of, host macrophages, which are eventually destroyed. The host is defined as the larger of the organisms involved in a symbiotic interaction.
42785	active evasion of host immune response via regulation of host cytokine network	P	Any mechanism of active immune avoidance which works by regulating host cytokine networks, e.g. by secreting proteins that mimic cytokine receptors that act to sequester host cytokines and inhibit action. The host is defined as the larger of the organisms involved in a symbiotic interaction.
42786	active evasion of host immune response via regulation of host antigen processing and presentation	P	Any mechanism of active immune avoidance which works by regulating the host's antigen processing or presentation pathways, e.g. by blocking any stage in MHC class II presentation. The host is defined as the larger of the organisms involved in a symbiotic interaction.
42787	protein ubiquitination involved in ubiquitin-dependent protein catabolic process	P	The process in which a ubiquitin group, or multiple groups, are covalently attached to the target protein, thereby initiating the degradation of that protein.
42788	polysomal ribosome	C	A ribosome bound to mRNA that forms part of a polysome.
42789	mRNA transcription from RNA polymerase II promoter	P	The cellular synthesis of messenger RNA (mRNA) from a DNA template by RNA polymerase II, originating at an RNA polymerase II promoter.
42790	transcription of nuclear large rRNA transcript from RNA polymerase I promoter	P	The synthesis of the large ribosomal RNA (rRNA) transcript which encodes several rRNAs, e.g. in mammals 28S, 18S and 5.8S, from a nuclear DNA template transcribed by RNA polymerase I.
42791	5S class rRNA transcription from RNA polymerase III type 1 promoter	P	The synthesis of 5S ribosomal RNA (rRNA), or an equivalent rRNA, from a DNA template by RNA polymerase III (Pol III), originating at a type 1 RNA polymerase III promoter.
42792	rRNA transcription from mitochondrial promoter	P	The synthesis of ribosomal RNA (rRNA) from a mitochondrial DNA template.
42793	transcription from plastid promoter	P	The synthesis of RNA from a plastid DNA template, usually by a specific plastid RNA polymerase.
42794	rRNA transcription from plastid promoter	P	The synthesis of ribosomal RNA (rRNA) from a plastid DNA template, usually by a specific plastid RNA polymerase.
42795	snRNA transcription from RNA polymerase II promoter	P	The synthesis of small nuclear RNA (snRNA) from a DNA template by RNA Polymerase II (Pol II), originating at a Pol II promoter.
42796	snRNA transcription from RNA polymerase III promoter	P	The synthesis of small nuclear RNA (snRNA) from a DNA template by RNA Polymerase III (Pol III), originating at a Pol III promoter.
42797	tRNA transcription from RNA polymerase III promoter	P	The synthesis of transfer RNA (tRNA) from a DNA template by RNA Polymerase III (Pol III), originating at a Pol III promoter.
42799	histone methyltransferase activity (H4-K20 specific)	F	Catalysis of the reaction: S-adenosyl-L-methionine + histone H4 L-lysine (position 20) = S-adenosyl-L-homocysteine + histone H4 N6-methyl-L-lysine (position 20). This reaction is the addition of a methyl group onto lysine at position 20 of the histone H4 protein.
42800	histone methyltransferase activity (H3-K4 specific)	F	Catalysis of the reaction: S-adenosyl-L-methionine + histone H3 L-lysine (position 4) = S-adenosyl-L-homocysteine + histone H3 N6-methyl-L-lysine (position 4). This reaction is the addition of a methyl group onto lysine at position 4 of the histone H3 protein.
42801	polo kinase kinase activity	F	Catalysis of the addition of a phosphate group onto a serine or threonine residue in any member of the polo kinase class of proteins.
42802	identical protein binding	F	Interacting selectively and non-covalently with an identical protein or proteins.
42803	protein homodimerization activity	F	Interacting selectively and non-covalently with an identical protein to form a homodimer.
42805	actinin binding	F	Interacting selectively and non-covalently with actinin, any member of a family of proteins that crosslink F-actin.
42806	fucose binding	F	Interacting selectively and non-covalently with fucose, the pentose 6-deoxygalactose.
42807	central vacuole	C	A membrane-enclosed sac that takes up most of the volume of a mature plant cell. Functions include storage, separation of toxic byproducts, and cell growth determination.
42809	vitamin D receptor binding	F	Interacting selectively and non-covalently with the vitamin D receptor, a nuclear receptor that mediates the action of vitamin D by binding DNA and controlling the transcription of hormone-sensitive genes.
42810	pheromone metabolic process	P	The chemical reactions and pathways involving pheromones, a substance that is secreted and released by an organism and detected by a second organism of the same or a closely related species, in which it causes a specific reaction, such as a definite behavioral reaction or a developmental process.
42811	pheromone biosynthetic process	P	The chemical reactions and pathways resulting in the formation of pheromones, a substance that is secreted and released by an organism and detected by a second organism of the same or a closely related species, in which it causes a specific reaction, such as a definite behavioral reaction or a developmental process.
42812	pheromone catabolic process	P	The chemical reactions and pathways resulting in the breakdown of pheromones, a substance that is secreted and released by an organism and detected by a second organism of the same or a closely related species, in which it causes a specific reaction, such as a definite behavioral reaction or a developmental process.
42813	Wnt-activated receptor activity	F	Combining with a Wnt protein and transmitting the signal across the plasma membrane to initiate a change in cell activity.
42814	monopolar cell growth	P	Polarized growth from one end of a cell.
42815	bipolar cell growth	P	The process in which a cell irreversibly increases in size along one axis through simultaneous polarized growth from opposite ends of a cell, resulting in morphogenesis of the cell.
42816	vitamin B6 metabolic process	P	The chemical reactions and pathways involving any of the vitamin B6 compounds: pyridoxal, pyridoxamine and pyridoxine and the active form, pyridoxal phosphate.
42817	pyridoxal metabolic process	P	The chemical reactions and pathways involving 3-hydroxy-5-(hydroxymethyl)-2-methyl-4-pyridinecarboxaldehyde, one of the vitamin B6 compounds. Pyridoxal, pyridoxamine and pyridoxine are collectively known as vitamin B6, and are efficiently converted to the biologically active form of vitamin B6, pyridoxal phosphate.
42818	pyridoxamine metabolic process	P	The chemical reactions and pathways involving 4-(aminomethyl)-5-(hydroxymethyl)-2-methylpyridin-3-ol, one of the vitamin B6 compounds. Pyridoxal, pyridoxamine and pyridoxine are collectively known as vitamin B6, and are efficiently converted to the biologically active form of vitamin B6, pyridoxal phosphate.
42819	vitamin B6 biosynthetic process	P	The chemical reactions and pathways resulting in the formation of any of the vitamin B6 compounds; pyridoxal, pyridoxamine and pyridoxine and the active form, pyridoxal phosphate.
42820	vitamin B6 catabolic process	P	The chemical reactions and pathways resulting in the breakdown of any of the vitamin B6 compounds; pyridoxal, pyridoxamine and pyridoxine and the active form, pyridoxal phosphate.
42821	pyridoxal biosynthetic process	P	The chemical reactions and pathways resulting in the formation of 3-hydroxy-5-(hydroxymethyl)-2-methyl-4-pyridinecarboxaldehyde, one of the vitamin B6 compounds.
42822	pyridoxal phosphate metabolic process	P	The chemical reactions and pathways involving pyridoxal phosphate, pyridoxal phosphorylated at the hydroxymethyl group of C-5, the active form of vitamin B6.
42823	pyridoxal phosphate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of pyridoxal phosphate, pyridoxal phosphorylated at the hydroxymethyl group of C-5, the active form of vitamin B6.
42824	MHC class I peptide loading complex	C	A large, multisubunit complex which consists of the MHC class I-beta 2 microglobulin dimer, the transporter associated with antigen presentation (TAP), tapasin (an MHC-encoded membrane protein), the chaperone calreticulin and the thiol oxidoreductase ERp57. Functions in the assembly of peptides with newly synthesized MHC class I molecules.
42825	TAP complex	C	A heterodimer composed of the subunits TAP1 and TAP2 (transporter associated with antigen presentation). Functions in the transport of antigenic peptides from the cytosol to the lumen of the endoplasmic reticulum.
42826	histone deacetylase binding	F	Interacting selectively and non-covalently with the enzyme histone deacetylase.
42827	platelet dense granule	C	Electron-dense granule occurring in blood platelets that stores and secretes adenosine nucleotides and serotonin. They contain a highly condensed core consisting of serotonin, histamine, calcium, magnesium, ATP, ADP, pyrophosphate and membrane lysosomal proteins.
42832	defense response to protozoan	P	Reactions triggered in response to the presence of a protozoan that act to protect the cell or organism.
42834	peptidoglycan binding	F	Interacting selectively and non-covalently, in a non-covalent manner, with peptidoglycan, any of a class of glycoconjugates found in bacterial cell walls.
42835	BRE binding	F	Interacting selectively and non-covalently with the RNA element BRE (Bruno response element).
42836	D-glucarate metabolic process	P	The chemical reactions and pathways involving D-glucarate, the D-enantiomer of glucarate. D-glucarate is derived from either D-glucose or L-gulose.
42837	D-glucarate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of D-glucarate, the D-enantiomer of glucarate.
42838	D-glucarate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of D-glucarate, the D-enantiomer of glucarate.
42839	D-glucuronate metabolic process	P	The chemical reactions and pathways involving D-glucuronate, the D-enantiomer of glucuronate.
42840	D-glucuronate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of D-glucuronate, the D-enantiomer of glucuronate.
42841	D-glucuronate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of D-glucuronate, the D-enantiomer of glucuronate.
42842	D-xylose biosynthetic process	P	The chemical reactions and pathways resulting in the formation of D-xylose, a naturally occurring plant polysaccharide.
42843	D-xylose catabolic process	P	The chemical reactions and pathways resulting in the breakdown of D-xylose, a naturally occurring plant polysaccharide.
42844	glycol metabolic process	P	The chemical reactions and pathways involving glycol, a diol in which the two hydroxy groups are on different carbon atoms, usually but not necessarily adjacent.
42845	glycol biosynthetic process	P	The chemical reactions and pathways resulting in the formation of glycol, a diol in which the two hydroxy groups are on different carbon atoms, usually but not necessarily adjacent.
42846	glycol catabolic process	P	The chemical reactions and pathways resulting in the breakdown of glycol, a diol in which the two hydroxy groups are on different carbon atoms, usually but not necessarily adjacent.
42847	sorbose biosynthetic process	P	The chemical reactions and pathways resulting in the formation of sorbose, the ketohexose xylo-2-hexulose. Sorbose is produced commercially by fermentation and is used as an intermediate in the manufacture of ascorbic acid.
42848	sorbose catabolic process	P	The chemical reactions and pathways resulting in the breakdown of sorbose, the ketohexose xylo-2-hexulose. Sorbose is produced commercially by fermentation and is used as an intermediate in the manufacture of ascorbic acid.
42849	L-sorbose biosynthetic process	P	The chemical reactions and pathways resulting in the formation of L-sorbose, the L-enantiomer of the ketohexose xylo-2-hexulose. L-sorbose is formed by bacterial oxidation of sorbitol.
42850	L-sorbose catabolic process	P	The chemical reactions and pathways resulting in the breakdown of L-sorbose, the L-enantiomer of the ketohexose xylo-2-hexulose.
42851	L-alanine metabolic process	P	The chemical reactions and pathways involving L-alanine, the L-enantiomer of 2-aminopropanoic acid, i.e. (2S)-2-aminopropanoic acid.
42852	L-alanine biosynthetic process	P	The chemical reactions and pathways resulting in the formation of L-alanine, the L-enantiomer of 2-aminopropanoic acid, i.e. (2S)-2-aminopropanoic acid.
42853	L-alanine catabolic process	P	The chemical reactions and pathways resulting in the breakdown of L-alanine, the L-enantiomer of 2-aminopropanoic acid, i.e. (2S)-2-aminopropanoic acid.
42854	eugenol metabolic process	P	The chemical reactions and pathways involving eugenol, a colorless, aromatic, liquid hydrocarbon (C10H12O2) found in clove oil.
42855	eugenol biosynthetic process	P	The chemical reactions and pathways resulting in the formation of eugenol, a colorless, aromatic, liquid hydrocarbon (C10H12O2) found in clove oil.
42856	eugenol catabolic process	P	The chemical reactions and pathways resulting in the breakdown of eugenol, a colorless, aromatic, liquid hydrocarbon (C10H12O2) found in clove oil.
42857	chrysobactin metabolic process	P	The chemical reactions and pathways involving the siderophore chrysobactin (alpha-N-(2,3-dihydroxybenzoyl)-D-lysyl-L-serine).
42858	chrysobactin biosynthetic process	P	The chemical reactions and pathways resulting in the formation of the siderophore chrysobactin (alpha-N-(2,3-dihydroxybenzoyl)-D-lysyl-L-serine).
42859	chrysobactin catabolic process	P	The chemical reactions and pathways resulting in the breakdown of the siderophore chrysobactin (alpha-N-(2,3-dihydroxybenzoyl)-D-lysyl-L-serine).
42860	achromobactin metabolic process	P	The chemical reactions and pathways involving achromobactin, a citrate siderophore.
42861	achromobactin biosynthetic process	P	The chemical reactions and pathways resulting in the formation of achromobactin, a citrate siderophore.
42862	achromobactin catabolic process	P	The chemical reactions and pathways resulting in the breakdown of achromobactin, a citrate siderophore.
42863	pyochelin metabolic process	P	The chemical reactions and pathways involving the siderochrome pyochelin (2-(2-o-hydroxyphenyl-2-thiazolin-4-yl)-3-methylthiazolidine-4-carboxylic acid).
42864	pyochelin biosynthetic process	P	The chemical reactions and pathways resulting in the formation of the siderochrome pyochelin (2-(2-o-hydroxyphenyl-2-thiazolin-4-yl)-3-methylthiazolidine-4-carboxylic acid).
42865	pyochelin catabolic process	P	The chemical reactions and pathways resulting in the breakdown of the siderochrome pyochelin (2-(2-o-hydroxyphenyl-2-thiazolin-4-yl)-3-methylthiazolidine-4-carboxylic acid).
42866	pyruvate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of pyruvate, 2-oxopropanoate.
42867	pyruvate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of pyruvate, 2-oxopropanoate.
42868	antisense RNA metabolic process	P	The chemical reactions and pathways involving antisense RNA, an RNA molecule complementary in sequence to another RNA or DNA molecule, which, by binding the latter, acts to inhibit its function and/or completion of synthesis.
42869	aldarate transport	P	The directed movement of aldarate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
42870	D-glucarate transport	P	The directed movement of D-glucarate, the D-enantiomer of glucarate, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
42873	aldonate transport	P	The directed movement of aldonate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
42874	D-glucuronate transport	P	The directed movement of D-glucuronate, the D-enantiomer of glucuronate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
42875	D-galactonate transport	P	The directed movement of D-galactonate, the D-enantiomer of galactonate, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
42876	aldarate transmembrane transporter activity	F	Enables the transfer of aldarate from one side of the membrane to the other.
42878	D-glucarate transmembrane transporter activity	F	Enables the transfer of D-glucarate, the D-enantiomer of glucarate, from one side of the membrane to the other.
42879	aldonate transmembrane transporter activity	F	Enables the transfer of aldonate from one side of the membrane to the other.
42880	D-glucuronate transmembrane transporter activity	F	Enables the transfer of D-glucuronate, the D-enantiomer of glucuronate, from one side of the membrane to the other.
42881	D-galactonate transmembrane transporter activity	F	Enables the transfer of D-galactonate, the D-enantiomer of galactonate, from one side of the membrane to the other.
42882	L-arabinose transport	P	The directed movement of L-arabinose, the L-enantiomer of arabinose, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
42883	cysteine transport	P	The directed movement of cysteine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
42884	microcin transport	P	The directed movement of microcin, a class of glycine-rich, bactericidal peptides (antibiotics) produced by some enteric bacteria, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
42885	microcin B17 transport	P	The directed movement of microcin B17, a bactericidal peptide (antibiotic) produced by some enteric bacteria, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
42886	amide transport	P	The directed movement of an amide, any compound containing one, two, or three acyl groups attached to a nitrogen atom, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
42887	amide transmembrane transporter activity	F	Enables directed movement of an amide, any compound containing one, two, or three acyl groups attached to a nitrogen atom, from one side of the membrane to the other.
42888	molybdenum ion transmembrane transporter activity	F	Enables the transfer of molybdenum (Mo) ions from one side of a membrane to the other.
42889	3-phenylpropionic acid transport	P	The directed movement of 3-phenylpropionic acid into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
42890	3-phenylpropionic acid transmembrane transporter activity	F	Enables the transfer of 3-phenylpropionic acid from one side of the membrane to the other.
42891	antibiotic transport	P	The directed movement of an antibiotic, a substance produced by or derived from certain fungi, bacteria, and other organisms, that can destroy or inhibit the growth of other microorganisms, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
42892	chloramphenicol transport	P	The directed movement of chloramphenicol, a broad-spectrum antibiotic that inhibits bacterial protein synthesis, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
42893	polymyxin transport	P	The directed movement of polymyxin, any of a group of related antibiotics produced by Bacillus polymyxa and active against most Gram-negative bacteria, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
42894	fosmidomycin transport	P	The directed movement of fosmidomycin, a phosphonic acid derivative with potent activity against Gram-negative organisms, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
42895	antibiotic transporter activity	F	Enables the directed movement of an antibiotic, a substance produced by or derived from certain fungi, bacteria, and other organisms, that can destroy or inhibit the growth of other microorganisms, into, out of or within a cell, or between cells.
42896	chloramphenicol transporter activity	F	Enables the directed movement of chloramphenicol, a broad-spectrum antibiotic that inhibits bacterial protein synthesis, into, out of or within a cell, or between cells.
42897	polymyxin transporter activity	F	Enables the directed movement of polymyxin, any of a group of related antibiotics produced by Bacillus polymyxa and active against most Gram-negative bacteria, into, out of or within a cell, or between cells.
42898	fosmidomycin transporter activity	F	Enables the directed movement of fosmidomycin, a phosphonic acid derivative with potent activity against Gram-negative organisms, into, out of or within a cell, or between cells.
42899	arabinan transport	P	The directed movement of arabinan, a polysaccharide composed of arabinose residues, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
42900	arabinose transmembrane transporter activity	F	Enables the transfer of arabinose, a pentose monosaccharide that occurs in both D and L configurations, and as a polymer, from one side of the membrane to the other.
42901	arabinan transmembrane transporter activity	F	Enables the transfer of an arabinan, a polysaccharide composed of arabinose residues, from one side of the membrane to the other.
42902	peptidoglycan-protein cross-linking via L-threonyl-pentaglycyl-murein	P	The process of linking a protein to peptidoglycan via a carboxy terminal threonine carboxyl group through a pentaglycyl peptide to the lysine or diaminopimelic acid of the peptidoglycan.
42903	tubulin deacetylase activity	F	Catalysis of the reaction: N-acetyl(alpha-tubulin) + H2O = alpha-tubulin + acetate.
42904	9-cis-retinoic acid biosynthetic process	P	The chemical reactions and pathways resulting in the formation of 9-cis-retinoic acid, a metabolically active vitamin A derivative.
42905	9-cis-retinoic acid metabolic process	P	The chemical reactions and pathways involving 9-cis-retinoic acid, a metabolically active vitamin A derivative.
42906	xanthine transport	P	The directed movement of xanthine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Xanthine (2,6-dihydroxypurine) is a purine formed in the metabolic breakdown of guanine, but is not present in nucleic acids.
42907	xanthine transmembrane transporter activity	F	Enables the transfer of xanthine from one side of a membrane to the other. Xanthine (2,6-dihydroxypurine) is a purine formed in the metabolic breakdown of guanine, but is not present in nucleic acids.
42908	xenobiotic transport	P	The directed movement of a xenobiotic, a compound foreign to living organisms, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
42909	acridine transport	P	The directed movement of acridine (10-azaanthracene), a heterocyclic ring compound found in crude coal-tar anthracene, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
42910	xenobiotic transporter activity	F	Enables the directed movement of a xenobiotic, a compound foreign to living organisms, into, out of or within a cell, or between cells.
42911	acridine transporter activity	F	Enables the directed movement of acridine (10-azaanthracene), a heterocyclic ring compound found in crude coal-tar anthracene, into, out of or within a cell, or between cells.
42912	colicin transmembrane transporter activity	F	Enables the transfer of a colicin from one side of a membrane to the other. Colicins are a group of antibiotics produced by E. coli and related species that are encoded by a group of naturally occurring plasmids, e.g. Col E1.
42913	group A colicin transmembrane transporter activity	F	Enables the transfer of group A colicins (colicins E1, E2, E3, A, K, and N) from one side of a membrane to the other.
42914	colicin transport	P	The directed movement of a colicin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Colicins are a group of antibiotics produced by E. coli and related species that are encoded by a group of naturally occurring plasmids, e.g. Col E1.
42915	group A colicin transport	P	The directed movement of group A colicins (colicins E1, E2, E3, A, K, and N) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
42916	alkylphosphonate transport	P	The directed movement of an alkylphosphonate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
42917	alkylphosphonate transmembrane transporter activity	F	Enables the transfer of an alkylphosphonate from one side of a membrane to the other.
42918	alkanesulfonate transport	P	The directed movement of an alkanesulfonate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Alkanesulfonates are organic esters or salts of sulfonic acid containing an aliphatic hydrocarbon radical.
42919	benzoate transport	P	The directed movement of benzoate, the anion of benzoic acid (benzenecarboxylic acid) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
42920	3-hydroxyphenylpropionic acid transport	P	The directed movement of 3-hydroxyphenylpropionic acid into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
42921	glucocorticoid receptor signaling pathway	P	Any series of molecular signals generated as a consequence of a glucocorticoid binding to its receptor.
42922	neuromedin U receptor binding	F	Interacting selectively and non-covalently with one or more specific sites on a neuromedin U receptor.
42923	neuropeptide binding	F	Interacting selectively and non-covalently and stoichiometrically with neuropeptides, peptides with direct synaptic effects (peptide neurotransmitters) or indirect modulatory effects on the nervous system (peptide neuromodulators).
42924	neuromedin U binding	F	Interacting selectively and non-covalently and stoichiometrically with neuromedin U, a hypothalamic peptide involved in energy homeostasis and stress responses.
42925	benzoate transporter activity	F	Enables the directed movement of benzoate, the anion of benzoic acid (benzenecarboxylic acid) into, out of or within a cell, or between cells.
42926	3-hydroxyphenylpropionic acid transporter activity	F	Enables the directed movement of 3-hydroxyphenylpropionic acid into, out of or within a cell, or between cells.
42927	siderophore transporter activity	F	Enables the directed movement of siderophores, low molecular weight Fe(III)-chelating substances, into, out of or within a cell, or between cells.
42928	ferrichrome transport	P	The directed movement of a ferrichrome into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Ferrichromes are any of a group of growth-promoting Fe(III) chelates formed by various genera of microfungi. They are homodetic cyclic hexapeptides made up of a tripeptide of glycine (or other small neutral amino acids) and a tripeptide of an N'acyl-N4-hydroxy-L-ornithine.
42929	ferrichrome transporter activity	F	Enables the directed movement of a ferrichrome into, out of or within a cell, or between cells. Ferrichromes are any of a group of growth-promoting Fe(III) chelates formed by various genera of microfungi. They are homodetic cyclic hexapeptides made up of a tripeptide of glycine (or other small neutral amino acids) and a tripeptide of an N'acyl-N4-hydroxy-L-ornithine.
42930	enterobactin transport	P	The directed movement of the siderochrome enterobactin, a cyclic trimer of 2, 3 dihydroxybenzoylserine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
42931	enterobactin transporter activity	F	Enables the directed movement of the siderochrome enterochelin, a cyclic trimer of 2, 3 dihydroxybenzoylserine into, out of or within a cell, or between cells.
42932	chrysobactin transport	P	The directed movement of the siderophore chrysobactin (alpha-N-(2,3-dihydroxybenzoyl)-D-lysyl-L-serine) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
42933	chrysobactin transporter activity	F	Enables the directed movement of the siderophore chrysobactin (alpha-N-(2,3-dihydroxybenzoyl)-D-lysyl-L-serine) into, out of or within a cell, or between cells.
42934	achromobactin transporter activity	F	Enables the directed movement of achromobactin, a citrate siderophore, into, out of or within a cell, or between cells.
42935	achromobactin transport	P	The directed movement of achromobactin, a citrate siderophore, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
42936	dipeptide transporter activity	F	Enables the directed movement of a dipeptide, a combination of two amino acids by means of a peptide (-CO-NH-) link, into, out of or within a cell, or between cells.
42937	tripeptide transporter activity	F	Enables the directed movement of a tripeptide, a compound containing three amino acids linked together by peptide bonds, into, out of or within a cell, or between cells.
42938	dipeptide transport	P	The directed movement of a dipeptide, a combination of two amino acids by means of a peptide (-CO-NH-) link, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
42939	tripeptide transport	P	The directed movement of a tripeptide, a compound containing three amino acids linked together by peptide bonds, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
42940	D-amino acid transport	P	The directed movement of the D-enantiomer of an amino acid into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
42941	D-alanine transport	P	The directed movement of D-alanine, the D-enantiomer of 2-aminopropanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
42942	D-serine transport	P	The directed movement of D-serine, the D-enantiomer of 2-amino-3-hydroxypropanoic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
42943	D-amino acid transmembrane transporter activity	F	Enables the transfer of D-amino acids from one side of a membrane to the other. D-amino acids are the D-enantiomers of amino acids.
42944	D-alanine transmembrane transporter activity	F	Enables the transfer of D-alanine from one side of a membrane to the other. D-alanine is the D-enantiomer of 2-aminopropanoic acid.
42945	D-serine transmembrane transporter activity	F	Enables the transfer of D-serine from one side of a membrane to the other. D-serine is the D-enantiomer of 2-amino-3-hydroxypropanoic acid.
42946	glucoside transport	P	The directed movement of glucosides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Glucosides are glycosides in which the sugar group is a glucose residue.
42947	glucoside transmembrane transporter activity	F	Enables the transfer of glucosides from one side of the membrane to the other. Glucosides are glycosides in which the sugar group is a glucose residue.
42948	salicin transport	P	The directed movement of salicin (saligenin-beta-D-glucopyranoside), a glucoside of o-hydroxybenzylalcohol, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
42949	arbutin transport	P	The directed movement of arbutin, a glycoside found in the bearberry and related plants which has been used to treat urinary-tract diseases, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
42950	salicin transmembrane transporter activity	F	Enables the transfer of salicin (saligenin-beta-D-glucopyranoside), a glucoside of o-hydroxybenzylalcohol, from one side of the membrane to the other.
42951	arbutin transmembrane transporter activity	F	Enables the transfer of arbutin, a glycoside found in the bearberry and related plants which has been used to treat urinary-tract diseases, from one side of the membrane to the other.
42952	beta-ketoadipate pathway	P	A pathway of aromatic compound degradation by ortho-cleavage; one branch converts protocatechuate, derived from phenolic compounds, to beta-ketoadipate, and the other branch converts catechol, generated from various aromatic hydrocarbons, amino aromatics, and lignin monomers, also to beta-ketoadipate. Two additional steps accomplish the conversion of beta-ketoadipate to tricarboxylic acid cycle intermediates.
42953	lipoprotein transport	P	The directed movement of any conjugated, water-soluble protein in which the nonprotein group consists of a lipid or lipids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
42954	lipoprotein transporter activity	F	Enables the directed movement of any conjugated, water-soluble protein in which the nonprotein group consists of a lipid or lipids, into, out of or within a cell, or between cells.
42955	dextrin transport	P	The directed movement of dextrin, any one, or the mixture, of the intermediate polysaccharides formed during the hydrolysis of starch, which are dextrorotatory, soluble in water, and precipitable in alcohol, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
42956	maltodextrin transport	P	The directed movement of maltodextrin, any polysaccharide of glucose residues in beta-(1,4) linkage, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
42957	dextrin transmembrane transporter activity	F	Enables the transfer of dextrin, any one, or the mixture, of the intermediate polysaccharides formed during the hydrolysis of starch, which are dextrorotatory, soluble in water, and precipitable in alcohol, from one side of the membrane to the other.
42958	maltodextrin transmembrane transporter activity	F	Enables the transfer of maltodextrin, any polysaccharide of glucose residues in beta-(1,4) linkage, from one side of the membrane to the other.
42959	alkanesulfonate transporter activity	F	Enables the directed movement of alkanesulfonate into, out of or within a cell, or between cells.
42960	antimonite secondary active transmembrane transporter activity	F	Catalysis of the transfer of antimonite from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Chemiosmotic sources of energy include uniport, symport or antiport.
42961	antimonite-transporting ATPase activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + antimonite(in) = ADP + phosphate + antimonite(out).
42962	acridine:proton antiporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + acridine(in) = H+(in) + acridine(out).
42964	thioredoxin biosynthetic process	P	The chemical reactions and pathways resulting in the formation of thioredoxin, a small disulfide-containing redox protein that serves as a general protein disulfide oxidoreductase.
42965	glutaredoxin biosynthetic process	P	The chemical reactions and pathways resulting in the formation of a small disulfide-containing redox protein that serves as a glutathione-disulfide oxidoreductase.
42966	biotin carboxyl carrier protein biosynthetic process	P	The chemical reactions and pathways resulting in the formation of the biotin carboxyl carrier protein, a subunit of acetyl-coenzyme A carboxylase.
42967	acyl-carrier-protein biosynthetic process	P	The chemical reactions and pathways resulting in the formation of acyl-carrier protein.
42968	homoserine transport	P	The directed movement of homoserine, alpha-amino-gamma-hydroxybutyric acid, an intermediate in the biosynthesis of cystathionine, threonine and methionine, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
42969	lactone transport	P	The directed movement of lactone from one side of a membrane to the other. A lactone is a cyclic ester of a hydroxy carboxylic acid, containing a 1-oxacycloalkan-2-one structure, or an analogue having unsaturation or heteroatoms replacing one or more carbon atoms of the ring.
42970	homoserine transmembrane transporter activity	F	Enables the transfer of homoserine from one side of a membrane to the other. Homoserine is alpha-amino-gamma-hydroxybutyric acid, an intermediate in the biosynthesis of cystathionine, threonine and methionine.
42971	lactone transmembrane transporter activity	F	Enables the directed movement of lactone from one side of a membrane to the other. A lactone is a cyclic ester of a hydroxy carboxylic acid, containing a 1-oxacycloalkan-2-one structure, or an analogue having unsaturation or heteroatoms replacing one or more carbon atoms of the ring.
42972	licheninase activity	F	Catalysis of the hydrolysis of (1->4)-beta-D-glucosidic linkages in beta-D-glucans containing (1->3) and (1->4) bonds.
42973	glucan endo-1,3-beta-D-glucosidase activity	F	Catalysis of the hydrolysis of (1->3)-beta-D-glucosidic linkages in (1->3)-beta-D-glucans.
42974	retinoic acid receptor binding	F	Interacting selectively and non-covalently with the retinoic acid receptor, a ligand-regulated transcription factor belonging to the nuclear receptor superfamily.
42975	peroxisome proliferator activated receptor binding	F	Interacting selectively and non-covalently with any of the peroxisome proliferator activated receptors, alpha, beta or gamma.
42976	activation of Janus kinase activity	P	The process of introducing a phosphate group to a tyrosine residue of a JAK (Janus Activated Kinase) protein, thereby activating it.
42977	activation of JAK2 kinase activity	P	The process of introducing a phosphate group to a tyrosine residue of a JAK2 (Janus Activated Kinase 2) protein, thereby activating it.
42978	ornithine decarboxylase activator activity	F	Upregulation of the activity of the enzyme ornithine decarboxylase.
42979	ornithine decarboxylase regulator activity	F	Modulation of the activity of the enzyme ornithine decarboxylase.
42981	regulation of apoptotic process	P	Any process that modulates the occurrence or rate of cell death by apoptotic process.
42982	amyloid precursor protein metabolic process	P	The chemical reactions and pathways involving amyloid precursor protein (APP), the precursor of beta-amyloid, a glycoprotein associated with Alzheimer's disease.
42983	amyloid precursor protein biosynthetic process	P	The chemical reactions and pathways resulting in the formation of amyloid precursor protein (APP), the precursor of beta-amyloid, a glycoprotein associated with Alzheimer's disease.
42984	regulation of amyloid precursor protein biosynthetic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of amyloid precursor protein (APP), the precursor of beta-amyloid.
42985	negative regulation of amyloid precursor protein biosynthetic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of amyloid precursor protein (APP), the precursor of beta-amyloid.
42986	positive regulation of amyloid precursor protein biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of amyloid precursor protein (APP), the precursor of beta-amyloid.
42987	amyloid precursor protein catabolic process	P	The chemical reactions and pathways resulting in the breakdown of amyloid precursor protein (APP), the precursor of beta-amyloid, a glycoprotein associated with Alzheimer's disease.
42988	X11-like protein binding	F	Interacting selectively and non-covalently with X11-like protein, a neuron-specific adaptor protein.
42989	sequestering of actin monomers	P	The selective interaction of actin monomers with specific molecules that inhibit their polymerization by preventing their access to other monomers.
42990	regulation of transcription factor import into nucleus	P	Any process that modulates the frequency, rate or extent of the movement of a transcription factor from the cytoplasm to the nucleus.
42991	transcription factor import into nucleus	P	The directed movement of a transcription factor from the cytoplasm to the nucleus.
42992	negative regulation of transcription factor import into nucleus	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the movement of a transcription factor from the cytoplasm to the nucleus.
42993	positive regulation of transcription factor import into nucleus	P	Any process that activates or increases the frequency, rate or extent of the movement of a transcription factor from the cytoplasm to the nucleus.
42994	cytoplasmic sequestering of transcription factor	P	The selective interaction of a transcription factor with specific molecules in the cytoplasm, thereby inhibiting its translocation into the nucleus.
42995	cell projection	C	A prolongation or process extending from a cell, e.g. a flagellum or axon.
42996	regulation of Golgi to plasma membrane protein transport	P	Any process that modulates the frequency, rate or extent of the transport of proteins from the Golgi to the plasma membrane.
42997	negative regulation of Golgi to plasma membrane protein transport	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the transport of proteins from the Golgi to the plasma membrane.
42998	positive regulation of Golgi to plasma membrane protein transport	P	Any process that activates or increases the frequency, rate or extent of the transport of proteins from the Golgi to the plasma membrane.
42999	regulation of Golgi to plasma membrane CFTR protein transport	P	Any process that modulates the frequency, rate or extent of transport of Cystic Fibrosis Transmembrane conductance Regulator (CFTR) protein from the Golgi to the plasma membrane.
43000	Golgi to plasma membrane CFTR protein transport	P	The directed movement of Cystic Fibrosis Transmembrane conductance Regulator (CFTR) protein from the Golgi to the plasma membrane.
43001	Golgi to plasma membrane protein transport	P	The directed movement of proteins from the Golgi to the plasma membrane in transport vesicles that move from the trans-Golgi network to the plasma membrane.
43002	negative regulation of Golgi to plasma membrane CFTR protein transport	P	Any process that stops, prevents, or reduces the frequency, rate or extent of transport of Cystic Fibrosis Transmembrane conductance Regulator (CFTR) protein from the Golgi to the plasma membrane.
43003	positive regulation of Golgi to plasma membrane CFTR protein transport	P	Any process that activates or increases the frequency, rate or extent of transport of Cystic Fibrosis Transmembrane conductance Regulator (CFTR) protein from the Golgi to the plasma membrane.
43004	cytoplasmic sequestering of CFTR protein	P	The selective interaction of Cystic Fibrosis Transmembrane conductance Regulator (CFTR) protein with specific molecules in the cytoplasm, thereby inhibiting its transport to the cell membrane.
43005	neuron projection	C	A prolongation or process extending from a nerve cell, e.g. an axon or dendrite.
43006	activation of phospholipase A2 activity by calcium-mediated signaling	P	A series of molecular signals that leads to the upregulation of calcium-dependent phospholipase A2 activity in response to the signal.
43007	maintenance of rDNA	P	Any process involved in sustaining the fidelity and copy number of rDNA repeats.
43008	ATP-dependent protein binding	F	Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules) using energy from the hydrolysis of ATP.
43009	chordate embryonic development	P	The process whose specific outcome is the progression of the embryo over time, from zygote formation through a stage including a notochord and neural tube until birth or egg hatching.
43010	camera-type eye development	P	The process whose specific outcome is the progression of the camera-type eye over time, from its formation to the mature structure. The camera-type eye is an organ of sight that receives light through an aperture and focuses it through a lens, projecting it on a photoreceptor field.
43011	myeloid dendritic cell differentiation	P	The process in which a monocyte acquires the specialized features of a dendritic cell, an immunocompetent cell of the lymphoid and hemopoietic systems and skin.
43012	regulation of fusion of sperm to egg plasma membrane	P	Any process that modulates the binding and fusion of a sperm to the oocyte plasma membrane.
43013	negative regulation of fusion of sperm to egg plasma membrane	P	Any process that stops or prevents the binding and fusion of a sperm to the oocyte plasma membrane.
43014	alpha-tubulin binding	F	Interacting selectively and non-covalently with the microtubule constituent protein alpha-tubulin.
43015	gamma-tubulin binding	F	Interacting selectively and non-covalently with the microtubule constituent protein gamma-tubulin.
43016	regulation of lymphotoxin A biosynthetic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of the cytokine lymphotoxin A.
43017	positive regulation of lymphotoxin A biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of the cytokine lymphotoxin A.
43018	negative regulation of lymphotoxin A biosynthetic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of the cytokine lymphotoxin A.
43020	NADPH oxidase complex	C	A enzyme complex of which the core is a heterodimer composed of a light (alpha) and heavy (beta) chain, and requires several other water-soluble proteins of cytosolic origin for activity. Functions in superoxide generation by the NADPH-dependent reduction of O2.
43021	ribonucleoprotein complex binding	F	Interacting selectively and non-covalently with any complex of RNA and protein.
43022	ribosome binding	F	Interacting selectively and non-covalently with any part of a ribosome.
43023	ribosomal large subunit binding	F	Interacting selectively and non-covalently with any part of the larger ribosomal subunit.
43024	ribosomal small subunit binding	F	Interacting selectively and non-covalently with any part of the small ribosomal subunit.
43025	neuronal cell body	C	The portion of a neuron that includes the nucleus, but excludes cell projections such as axons and dendrites.
43027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process	F	Stops, prevents or reduces the activity of a cysteine-type endopeptidase involved in the apoptotic process.
43028	cysteine-type endopeptidase regulator activity involved in apoptotic process	F	Modulates the activity of a cysteine-type endopeptidase involved in the apoptotic process.
43029	T cell homeostasis	P	The process of regulating the proliferation and elimination of T cells such that the total number of T cells within a whole or part of an organism is stable over time in the absence of an outside stimulus.
43030	regulation of macrophage activation	P	Any process that modulates the frequency or rate of macrophage activation.
43031	negative regulation of macrophage activation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of macrophage activation.
43032	positive regulation of macrophage activation	P	Any process that stimulates, induces or increases the rate of macrophage activation.
43033	isoamylase complex	C	A protein complex whose composition varies amongst species; in rice it probably exists in a homo-tetramer to homo-hexamer form and in Gram-negative bacteria as a dimer. Functions in the hydrolysis of alpha-(1,6)-D-glucosidic branch linkages.
43034	costamere	C	Regular periodic sub membranous arrays of vinculin in skeletal and cardiac muscle cells, these arrays link Z-discs to the sarcolemma and are associated with links to extracellular matrix.
43035	chromatin insulator sequence binding	F	Interacting selectively and non-covalently and stoichiometrically with a chromatin insulator sequence, a DNA sequence that prevents enhancer-mediated activation or repression of transcription.
43036	starch grain	C	Plant storage body for amylose and amylopectin, 1-100um in diameter. Also contains small amounts of enzymes, amino acids, lipids and nucleic acids. The shape of the grain varies widely amongst species, but is often spherical or disk-shaped.
43038	amino acid activation	P	The modification of an amino acid to an active form, for incorporation into a peptide, protein or other macromolecule.
43039	tRNA aminoacylation	P	The chemical reactions and pathways by which the various amino acids become bonded to their corresponding tRNAs. The most common route for synthesis of aminoacyl tRNA is by the formation of an ester bond between the 3'-hydroxyl group of the most 3' adenosine of the tRNA, usually catalyzed by the cognate aminoacyl-tRNA ligase. A given aminoacyl-tRNA ligase aminoacylates all species of an isoaccepting group of tRNA molecules.
43040	tRNA aminoacylation for nonribosomal peptide biosynthetic process	P	The synthesis of aminoacyl tRNA by the formation of an ester bond between the 3'-hydroxyl group of the most 3' adenosine of the tRNA, to be used in nonribosomal peptide synthesis.
43041	amino acid activation for nonribosomal peptide biosynthetic process	P	Activation of an amino acid for incorporation into a peptide by a nonribosomal process.
43042	amino acid adenylylation by nonribosomal peptide synthase	P	Activation of an amino acid for incorporation into a peptide by a nonribosomal process, catalyzed by subunits of nonribosomal peptide synthase. The amino acid is adenylated at its carboxylate group (ATP-dependent) then transferred to the thiol group of an enzyme-bound phosphopantetheine cofactor.
43043	peptide biosynthetic process	P	The chemical reactions and pathways resulting in the formation of peptides, compounds of 2 or more (but usually less than 100) amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another. This may include the translation of a precursor protein and its subsequent processing into a functional peptide.
43044	ATP-dependent chromatin remodeling	P	Dynamic structural changes to eukaryotic chromatin that require energy from the hydrolysis of ATP, ranging from local changes necessary for transcriptional regulation to global changes necessary for chromosome segregation, mediated by ATP-dependent chromatin-remodelling factors.
43045	DNA methylation involved in embryo development	P	The covalent transfer of a methyl group to C-5 of cytosine that contributes to the epigenetic regulation of embryonic gene expression.
43046	DNA methylation involved in gamete generation	P	The covalent transfer of a methyl group to C-5 of cytosine that contributes to the establishment of DNA methylation patterns in the gamete.
43047	single-stranded telomeric DNA binding	F	Interacting selectively and non-covalently with single-stranded telomere-associated DNA.
43048	dolichyl monophosphate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of dolichyl diphosphate, a phosphorylated dolichol derivative.
43049	otic placode formation	P	The initial developmental process that will lead to the formation of the vertebrate inner ear. The otic placode forms as a thickening of the head ectoderm adjacent to the developing hindbrain.
43050	pharyngeal pumping	P	The contraction and relaxation movements of the pharyngeal muscle that mediate feeding in nematodes.
43051	regulation of pharyngeal pumping	P	Any process that modulates the contraction and relaxation movements of the pharyngeal muscle that mediates feeding in nematodes.
43052	thermotaxis	P	The directed movement of a motile cell or organism in response to a temperature gradient. Movement may be towards either a higher or lower temperature.
43053	dauer entry	P	Entry into the facultative diapause of the dauer (enduring) larval stage of nematode development.
43054	dauer exit	P	Exit from the facultative diapause of the dauer (enduring) larval stage of nematode development.
43055	maintenance of dauer	P	Maintenance of a nematode during the facultative diapause of the dauer (enduring) larval stage of nematode development.
43056	forward locomotion	P	Anterior movement of an organism, following the direction of the head of the animal.
43057	backward locomotion	P	Posterior movement of an organism, e.g. following the direction of the tail of an animal.
43058	regulation of backward locomotion	P	Any process that modulates the speed, mechanical force, or rhythm of the posterior movement of an organism.
43059	regulation of forward locomotion	P	Any process that modulates the speed, mechanical force, or rhythm of the anterior movement of an organism.
43060	meiotic metaphase I plate congression	P	The alignment of chromosomes at the metaphase plate, a plane halfway between the poles of the meiotic spindle, during meiosis I.
43061	meiotic metaphase II plate congression	P	The alignment of chromosomes at the metaphase plate, a plane halfway between the poles of the meiotic spindle, during meiosis II.
43062	extracellular structure organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of structures in the space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane, and also covers the host cell environment outside an intracellular parasite.
43063	intercellular bridge organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the intracellular bridge. An intracellular bridge is a direct link between the cytoplasms of sister cells that allows cells to communicate with one another.
43065	positive regulation of apoptotic process	P	Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process.
43066	negative regulation of apoptotic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process.
43067	regulation of programmed cell death	P	Any process that modulates the frequency, rate or extent of programmed cell death, cell death resulting from activation of endogenous cellular processes.
43068	positive regulation of programmed cell death	P	Any process that activates or increases the frequency, rate or extent of programmed cell death, cell death resulting from activation of endogenous cellular processes.
43069	negative regulation of programmed cell death	P	Any process that stops, prevents, or reduces the frequency, rate or extent of programmed cell death, cell death resulting from activation of endogenous cellular processes.
43073	germ cell nucleus	C	The nucleus of a germ cell, a reproductive cell in multicellular organisms.
43076	megasporocyte nucleus	C	The nucleus of a megasporocyte, a diploid cell that undergoes meiosis to produce four megaspores, and its descendents.
43077	initiation of acetate catabolic process	P	The activation of the chemical reactions and pathways resulting in the breakdown of acetate.
43078	polar nucleus	C	Either of two nuclei located centrally in a flowering plant embryo sac that eventually fuse to form the endosperm nucleus.
43079	antipodal cell nucleus	C	The nucleus of an antipodal cell, one of three cells of the embryo sac in angiosperms, found at the chalazal end of the embryo away from the point of entry of the pollen tube, and its descendents.
43082	megagametophyte egg cell nucleus	C	The nucleus of a plant egg cell. This nucleus is found at the micropylar end of the embryo.
43083	synaptic cleft	C	The narrow gap that separates the presynaptic and postsynaptic membranes, into which neurotransmitter is released.
43084	penile erection	P	The hardening, enlarging and rising of the penis which often occurs in the sexually aroused male and enables sexual intercourse. Achieved by increased inflow of blood into the vessels of erectile tissue, and decreased outflow.
43085	positive regulation of catalytic activity	P	Any process that activates or increases the activity of an enzyme.
43086	negative regulation of catalytic activity	P	Any process that stops or reduces the activity of an enzyme.
43087	regulation of GTPase activity	P	Any process that modulates the rate of GTP hydrolysis by a GTPase.
43090	amino acid import	P	The directed movement of amino acids into a cell or organelle.
43091	L-arginine import	P	The directed movement of L-arginine, the L-enantiomer of 2-amino-5-guanidinopentanoic acid, into a cell or organelle.
43092	L-amino acid import	P	The directed movement of L-enantiomer amino acids into a cell or organelle.
43093	FtsZ-dependent cytokinesis	P	A cytokinesis process that involves a set of conserved proteins including FtsZ, and results in the formation of two similarly sized and shaped cells.
43094	cellular metabolic compound salvage	P	Any process which produces a useful metabolic compound from derivatives of it without de novo synthesis, as carried out by individual cells.
43095	regulation of GTP cyclohydrolase I activity	P	Any process that modulates the activity of the enzyme GTP cyclohydrolase I.
43096	purine nucleobase salvage	P	Any process that generates purine nucleobases, one of the two classes of nitrogen-containing ring compounds found in DNA and RNA, from derivatives of them without de novo synthesis.
43097	pyrimidine nucleoside salvage	P	Any process that generates a pyrimidine nucleoside, one of a family of organic molecules consisting of a pyrimidine base covalently bonded to a sugar ribose, from derivatives of it, without de novo synthesis.
43098	purine deoxyribonucleoside salvage	P	Any process which produces a purine deoxyribonucleoside from derivatives of it, without de novo synthesis.
43099	pyrimidine deoxyribonucleoside salvage	P	Any process that generates a pyrimidine deoxyribonucleoside from derivatives of it, without de novo synthesis.
43100	pyrimidine nucleobase salvage	P	Any process that generates pyrimidine nucleobases, 1,3-diazine organic nitrogenous bases, from derivatives of them without de novo synthesis.
43101	purine-containing compound salvage	P	Any process that generates a purine-containing compound, any nucleobase, nucleoside, nucleotide or nucleic acid that contains a purine base, from derivatives of them without de novo synthesis.
43102	amino acid salvage	P	Any process which produces an amino acid from derivatives of it, without de novo synthesis.
43103	hypoxanthine salvage	P	Any process that generates hypoxanthine, 6-hydroxy purine, from derivatives of it without de novo synthesis.
43104	positive regulation of GTP cyclohydrolase I activity	P	Any process that activates or increases the activity of the enzyme GTP cyclohydrolase I.
43105	negative regulation of GTP cyclohydrolase I activity	P	Any process that stops or reduces the activity of the enzyme GTP cyclohydrolase I.
43107	type IV pilus-dependent motility	P	Any process involved in the controlled movement of a bacterial cell which is dependent on the presence of type IV pili. Includes social gliding motility and twitching motility.
43108	pilus retraction	P	The process of withdrawing a pilus back into a cell.
43110	rDNA spacer replication fork barrier binding	F	Interacting selectively and non-covalently with replication fork barriers found in rDNA spacers, sites that inhibit replication forks in the direction opposite to rDNA transcription.
43111	replication fork arrest	P	Any process that stops, prevents, or reduces the frequency, rate or extent of DNA replication by impeding the progress of the DNA replication fork. Replication fork arrest is one of the 'quality control' processes ensuring that DNA-dependent DNA replication occurs correctly. DNA replication fork arrest during DNA-dependent DNA replication is not known to occur outside of cases where a replication error needs to be prevented or corrected.
43112	receptor metabolic process	P	The chemical reactions and pathways involving a receptor molecule, a macromolecule that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.
43113	receptor clustering	P	The receptor metabolic process that results in grouping of a set of receptors at a cellular location, often to amplify the sensitivity of a signaling response.
43114	regulation of vascular permeability	P	Any process that modulates the extent to which blood vessels can be pervaded by fluid.
43115	precorrin-2 dehydrogenase activity	F	Catalysis of the reaction: NAD(+) + precorrin-2 = 2 H(+) + NADH + sirohydrochlorin.
43116	negative regulation of vascular permeability	P	Any process that reduces the extent to which blood vessels can be pervaded by fluid.
43117	positive regulation of vascular permeability	P	Any process that increases the extent to which blood vessels can be pervaded by fluid.
43120	tumor necrosis factor binding	F	Interacting selectively and non-covalently with tumor necrosis factor, a proinflammatory cytokine produced by monocytes and macrophages.
43121	neurotrophin binding	F	Interacting selectively and non-covalently with a neurotrophin, any of a family of growth factors that prevent apoptosis in neurons and promote nerve growth.
43122	regulation of I-kappaB kinase/NF-kappaB signaling	P	Any process that modulates I-kappaB kinase/NF-kappaB signaling.
43123	positive regulation of I-kappaB kinase/NF-kappaB signaling	P	Any process that activates or increases the frequency, rate or extent of I-kappaB kinase/NF-kappaB signaling.
43124	negative regulation of I-kappaB kinase/NF-kappaB signaling	P	Any process that stops, prevents, or reduces the frequency, rate or extent of -kappaB kinase/NF-kappaB signaling.
43125	ErbB-3 class receptor binding	F	Interacting selectively and non-covalently with the protein-tyrosine kinase receptor ErbB-3/HER3.
43126	regulation of 1-phosphatidylinositol 4-kinase activity	P	Any process that modulates the activity of the enzyme 1-phosphatidylinositol 4-kinase.
43127	negative regulation of 1-phosphatidylinositol 4-kinase activity	P	Any process that stops or reduces the activity of the enzyme 1-phosphatidylinositol 4-kinase.
43128	positive regulation of 1-phosphatidylinositol 4-kinase activity	P	Any process that activates or increases the activity of 1-phosphatidylinositol 4-kinase.
43129	surfactant homeostasis	P	Any process involved in the maintenance of a steady-state level of the surface-active lipoprotein mixture which coats the alveoli.
43130	ubiquitin binding	F	Interacting selectively and non-covalently with ubiquitin, a protein that when covalently bound to other cellular proteins marks them for proteolytic degradation.
43131	erythrocyte enucleation	P	The process in which nucleated precursor cells lose their nucleus during erythrocyte maturation.
43132	NAD transport	P	The directed movement of nicotinamide adenine dinucleotide into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore; transport may be of either the oxidized form, NAD, or the reduced form, NADH.
43133	hindgut contraction	P	A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the hindgut. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The hindgut is the posterior part of the alimentary canal, including the rectum, and the large intestine.
43134	regulation of hindgut contraction	P	Any process that modulates the frequency, rate or extent of muscle contraction of the hindgut, the posterior part of the alimentary canal, including the rectum, and the large intestine.
43135	5-phosphoribosyl 1-pyrophosphate pyrophosphatase activity	F	Catalysis of the reaction: 5-phospho-alpha-D-ribose 1-diphosphate + H2O = ribose 1,5 bisphosphate + phosphate + H+.
43136	glycerol-3-phosphatase activity	F	Catalysis of the reaction: glycerol 3-phosphate + H2O = glycerol + phosphate.
43137	DNA replication, removal of RNA primer	P	Removal of the Okazaki RNA primer from the lagging strand of replicating DNA, by a combination of the actions of DNA polymerase, DNA helicase and an endonuclease.
43138	3'-5' DNA helicase activity	F	Catalysis of the unwinding of the DNA helix in the direction 3' to 5'.
43139	5'-3' DNA helicase activity	F	Catalysis of the unwinding of the DNA helix in the direction 5' to 3'.
43140	ATP-dependent 3'-5' DNA helicase activity	F	Catalysis of the reaction: ATP + H2O = ADP + phosphate; drives the unwinding of the DNA helix in the direction 3' to 5'.
43141	ATP-dependent 5'-3' DNA helicase activity	F	Catalysis of the reaction: ATP + H2O = ADP + phosphate; drives the unwinding of the DNA helix in the direction 5' to 3'.
43142	single-stranded DNA-dependent ATPase activity	F	Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction requires the presence of single-stranded DNA, and it drives another reaction.
43143	regulation of translation by machinery localization	P	Any process in which proteins and protein complexes involved in translation are transported to, or maintained in, a specific location.
43144	snoRNA processing	P	Any process involved in the conversion of a primary small nucleolar RNA (snoRNA) transcript into a mature snoRNA.
43145	snoRNA 3'-end cleavage	P	The endonucleolytic cleavage of snoRNA 3' ends, which is required for mature snoRNAs to be functional.
43149	stress fiber assembly	P	The aggregation, arrangement and bonding together of a set of components to form a stress fiber. A stress fiber is a contractile actin filament bundle that consists of short actin filaments with alternating polarity.
43150	DNA synthesis involved in double-strand break repair via homologous recombination	P	The synthesis of DNA that contributes to the process of double-strand break repair via homologous recombination.
43151	DNA synthesis involved in double-strand break repair via single-strand annealing	P	The synthesis of DNA that contributes to the process of double-strand break repair via single-strand annealing.
43152	induction of bacterial agglutination	P	Any process in which infecting bacteria are clumped together by a host organism.
43153	entrainment of circadian clock by photoperiod	P	The synchronization of a circadian rhythm to photoperiod, the intermittent cycle of light (day) and dark (night).
43154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of a cysteine-type endopeptidase activity involved in the apoptotic process.
43155	negative regulation of photosynthesis, light reaction	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the light-dependent reaction of photosynthesis.
43156	chromatin remodeling in response to cation stress	P	Structural changes to eukaryotic chromatin occurring as a result of cation stress, an increase or decrease in the concentration of positively charged ions in the environment.
43157	response to cation stress	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of cation stress, an increase or decrease in the concentration of positively charged ions in the environment.
43158	heterocyst differentiation	P	The process in which a relatively unspecialized cell acquires specialized features of a heterocyst, a differentiated cell in certain cyanobacteria whose purpose is to fix nitrogen.
43159	acrosomal matrix	C	A structural framework, or 'dense core' at the interior of an acrosome. May regulate the distribution of hydrolases within the acrosome and their release during the acrosome reaction.
43160	acrosomal lumen	C	The volume enclosed within the acrosome membrane.
43161	proteasome-mediated ubiquitin-dependent protein catabolic process	P	The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the covalent attachment of ubiquitin, and mediated by the proteasome.
43162	ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway	P	The chemical reactions and pathways resulting in the breakdown of a protein or peptide covalently tagged with ubiquitin, via the multivesicular body (MVB) sorting pathway; ubiquitin-tagged proteins are sorted into MVBs, and delivered to a lysosome/vacuole for degradation.
43163	cell envelope organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the cell envelope, everything external to, but not including, the cytoplasmic membrane of bacteria, encompassing the periplasmic space, cell wall, and outer membrane if present.
43164	Gram-negative-bacterium-type cell wall biogenesis	P	A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cell wall of the type found in Gram-negative bacteria. The cell wall is the rigid or semi-rigid envelope lying outside the cell membrane.
43165	Gram-negative-bacterium-type cell outer membrane assembly	P	The assembly of an outer membrane of the type formed in Gram-negative bacteria. This membrane is enriched in polysaccharide and protein, and the outer leaflet of the membrane contains specific lipopolysaccharide structures.
43167	ion binding	F	Interacting selectively and non-covalently with ions, charged atoms or groups of atoms.
43168	anion binding	F	Interacting selectively and non-covalently with anions, charged atoms or groups of atoms with a net negative charge.
43169	cation binding	F	Interacting selectively and non-covalently with cations, charged atoms or groups of atoms with a net positive charge.
43170	macromolecule metabolic process	P	The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
43171	peptide catabolic process	P	The chemical reactions and pathways resulting in the breakdown of peptides, compounds of 2 or more (but usually less than 100) amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another.
43172	ferredoxin biosynthetic process	P	The chemical reactions and pathways resulting in the formation of ferredoxin, any simple, nonenzymatic iron-sulfur protein that is characterized by having equal numbers of atoms of iron and labile sulfur. Iron and sulfur atoms are present in one or two clusters of two or four atoms of each.
43173	nucleotide salvage	P	Any process which produces a nucleotide, a compound consisting of a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the glycose moiety, from derivatives of it without de novo synthesis.
43174	nucleoside salvage	P	Any process which produces a nucleotide, a nucleobase linked to either beta-D-ribofuranose (ribonucleoside) or 2-deoxy-beta-D-ribofuranose (a deoxyribonucleotide), from derivatives of it without de novo synthesis.
43175	RNA polymerase core enzyme binding	F	Interacting selectively and non-covalently with an RNA polymerase core enzyme, containing a specific subunit composition defined as the core enzyme.
43176	amine binding	F	Interacting selectively and non-covalently with any organic compound that is weakly basic in character and contains an amino or a substituted amino group.
43177	organic acid binding	F	Interacting selectively and non-covalently with an organic acid, any acidic compound containing carbon in covalent linkage.
43178	alcohol binding	F	Interacting selectively and non-covalently with an alcohol, any of a class of alkyl compounds containing a hydroxyl group.
43179	rhythmic excitation	P	Any process involved in the generation of rhythmic, synchronous excitatory synaptic inputs in a neural circuit.
43180	rhythmic inhibition	P	Any process involved in the generation of rhythmic, synchronous inhibitory synaptic inputs in a neural circuit.
43181	vacuolar sequestering	P	The process of transporting a substance into, and confining within, a vacuole.
43182	vacuolar sequestering of sodium ion	P	The process of transporting sodium ions into, and confining within, a vacuole.
43183	vascular endothelial growth factor receptor 1 binding	F	Interacting selectively and non-covalently with vascular endothelial growth factor receptor 1.
43184	vascular endothelial growth factor receptor 2 binding	F	Interacting selectively and non-covalently with vascular endothelial growth factor receptor 2.
43185	vascular endothelial growth factor receptor 3 binding	F	Interacting selectively and non-covalently with vascular endothelial growth factor receptor 3.
43186	P granule	C	A small cytoplasmic, non-membranous RNA/protein complex aggregates in the primordial germ cells of many higher eukaryotes.
43187	cell septum surface	C	The extracellular (rather than the intracellular) exterior of a dividing septum; this surface is usually composed of cell wall material, for example, lineal (1,3)-beta-D-glucan in S. pombe.
43188	cell septum edging	C	The cell wall material that surrounds the septum in fungal cells.
43189	H4/H2A histone acetyltransferase complex	C	A multisubunit complex that catalyzes the acetylation of histones H4 and H2A.
43190	ATP-binding cassette (ABC) transporter complex	C	A complex for the transport of metabolites into and out of the cell, typically comprised of four domains; two membrane-associated domains and two ATP-binding domains at the intracellular face of the membrane, that form a central pore through the plasma membrane. Each of the four core domains may be encoded as a separate polypeptide or the domains can be fused in any one of a number of ways into multidomain polypeptides. In Bacteria and Archaebacteria, ABC transporters also include substrate binding proteins to bind substrate external to the cytoplasm and deliver it to the transporter.
43194	axon initial segment	C	Portion of the axon proximal to the neuronal cell body, at the level of the axon hillock. The action potentials that propagate along the axon are generated at the level of this initial segment.
43195	terminal bouton	C	Terminal inflated portion of the axon, containing the specialized apparatus necessary to release neurotransmitters. The axon terminus is considered to be the whole region of thickening and the terminal bouton is a specialized region of it.
43196	varicosity	C	Non-terminal inflated portion of the axon, containing the specialized apparatus necessary to release neurotransmitters.
43197	dendritic spine	C	A small, membranous protrusion from a dendrite that forms a postsynaptic compartment - typically receiving input from a single presynapse. They function as partially isolated biochemical and an electrical compartments. Spine morphology is variable including "thin", "stubby", "mushroom", and "branched", with a continuum of intermediate morphologies. They typically terminate in a bulb shape, linked to the dendritic shaft by a restriction. Spine remodeling is though to be involved in synaptic plasticity.
43198	dendritic shaft	C	Cylindric portion of the dendrite, directly stemming from the perikaryon, and carrying the dendritic spines.
43199	sulfate binding	F	Interacting selectively and non-covalently with sulfate, SO4(2-), a negatively charged small molecule.
43200	response to amino acid	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amino acid stimulus. An amino acid is a carboxylic acids containing one or more amino groups.
43201	response to leucine	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a leucine stimulus.
43202	lysosomal lumen	C	The volume enclosed within the lysosomal membrane.
43203	axon hillock	C	Portion of the neuronal cell soma from which the axon originates.
43204	perikaryon	C	The portion of the cell soma (neuronal cell body) that excludes the nucleus.
43207	response to external biotic stimulus	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an external biotic stimulus, an external stimulus caused by, or produced by living things.
43208	glycosphingolipid binding	F	Interacting selectively and non-covalently with glycosphingolipid, a compound with residues of sphingoid and at least one monosaccharide.
43209	myelin sheath	C	An electrically insulating fatty layer that surrounds the axons of many neurons. It is an outgrowth of glial cells: Schwann cells supply the myelin for peripheral neurons while oligodendrocytes supply it to those of the central nervous system.
43210	alkanesulfonate binding	F	Interacting selectively and non-covalently with alkanesulfonates, the anion of alkanesulfonic acids, sulfonic acid derivatives containing an aliphatic hydrocarbon group.
43211	carbohydrate-transporting ATPase activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O = ADP + phosphate, to directly drive the transport of carbohydrates across a membrane.
43212	carbohydrate-exporting ATPase activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + carbohydrate(in) -> ADP + phosphate + carbohydrate(out).
43213	bacteriocin transport	P	The directed movement of a bacteriocin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Bacteriocins are a group of antibiotics produced by bacteria and are encoded by a group of naturally occurring plasmids, e.g. Col E1. Bacteriocins are toxic to bacteria closely related to the bacteriocin producing strain.
43214	bacteriocin-transporting ATPase activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O = ADP + phosphate; drives the transport of bacteriocins across a membrane.
43215	daunorubicin transport	P	The directed movement of daunorubicin, an anthracycline antibiotic produced by Streptomyces coeruleorubidus or S. peucetius and used as an antineoplastic into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
43216	daunorubicin-transporting ATPase activity	F	Catalysis of the reaction: ATP + H2O + daunorubicin(in) = ADP + phosphate + daunorubicin(out).
43217	myelin maintenance	P	The process of preserving the structure and function of mature myelin. This includes maintaining the compact structure of myelin necessary for its electrical insulating characteristics as well as the structure of non-compact regions such as Schmidt-Lantermann clefts and paranodal loops. This does not include processes responsible for maintaining the nodes of Ranvier, which are not part of the myelin sheath.
43218	compact myelin	C	The portion of the myelin sheath in which layers of cell membrane are tightly juxtaposed, completely excluding cytoplasm. The juxtaposed cytoplasmic surfaces form the major dense line, while the juxtaposed extracellular surfaces form the interperiod line visible in electron micrographs.
43219	lateral loop	C	Non-compact myelin located adjacent to the nodes of Ranvier in a myelin segment. These non-compact regions include cytoplasm from the cell responsible for synthesizing the myelin. Lateral loops are found in the paranodal region adjacent to the nodes of Ranvier, while Schmidt-Lantermann clefts are analogous structures found within the compact myelin internode.
43220	Schmidt-Lanterman incisure	C	Regions within compact myelin in which the cytoplasmic faces of the enveloping myelin sheath are not tightly juxtaposed, and include cytoplasm from the cell responsible for making the myelin. Schmidt-Lanterman incisures occur in the compact myelin internode, while lateral loops are analogous structures found in the paranodal region adjacent to the nodes of Ranvier.
43221	SMC family protein binding	F	Interacting selectively and non-covalently with any protein from the structural maintenance of chromosomes (SMC) family, a group of chromosomal ATPases with a role in mitotic chromosome organization.
43223	cytoplasmic SCF ubiquitin ligase complex	C	A ubiquitin ligase complex, located in the cytoplasm, in which a cullin from the Cul1 subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by a Skp1 adaptor and an F-box protein. SCF complexes are involved in targeting proteins for degradation by the proteasome. The best characterized complexes are those from yeast and mammals (with core subunits named Cdc53/Cul1, Rbx1/Hrt1/Roc1).
43224	nuclear SCF ubiquitin ligase complex	C	A ubiquitin ligase complex, located in the nucleus, in which a cullin from the Cul1 subfamily and a RING domain protein form the catalytic core; substrate specificity is conferred by a Skp1 adaptor and an F-box protein. SCF complexes are involved in targeting proteins for degradation by the proteasome. The best characterized complexes are those from yeast and mammals (with core subunits named Cdc53/Cul1, Rbx1/Hrt1/Roc1).
43225	ATPase-coupled anion transmembrane transporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + anion(out) = ADP + phosphate + anion(in).
43226	organelle	C	Organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, and prokaryotic structures such as anammoxosomes and pirellulosomes. Excludes the plasma membrane.
43227	membrane-bounded organelle	C	Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
43228	non-membrane-bounded organelle	C	Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane. Includes ribosomes, the cytoskeleton and chromosomes.
43229	intracellular organelle	C	Organized structure of distinctive morphology and function, occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.
43230	extracellular organelle	C	Organized structure of distinctive morphology and function, occurring outside the cell. Includes, for example, extracellular membrane vesicles (EMVs) and the cellulosomes of anaerobic bacteria and fungi.
43231	intracellular membrane-bounded organelle	C	Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
43232	intracellular non-membrane-bounded organelle	C	Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane and occurring within the cell. Includes ribosomes, the cytoskeleton and chromosomes.
43233	organelle lumen	C	The internal volume enclosed by the membranes of a particular organelle; includes the volume enclosed by a single organelle membrane, e.g. endoplasmic reticulum lumen, or the volume enclosed by the innermost of the two lipid bilayers of an organelle envelope, e.g. nuclear lumen.
43234	protein complex	C	A stable macromolecular complex composed (only) of two or more polypeptide subunits along with any covalently attached molecules (such as lipid anchors or oligosaccharide) or non-protein prosthetic groups (such as nucleotides or metal ions). Prosthetic group in this context refers to a tightly bound cofactor. The component polypeptide subunits may be identical.
43235	receptor complex	C	Any protein complex that undergoes combination with a hormone, neurotransmitter, drug or intracellular messenger to initiate a change in cell function.
43236	laminin binding	F	Interacting selectively and non-covalently with laminins, glycoproteins that are major constituents of the basement membrane of cells.
43237	laminin-1 binding	F	Interacting selectively and non-covalently with laminin-1, a glycoprotein trimer with the subunit composition alpha1, beta1, gamma1.
43240	Fanconi anaemia nuclear complex	C	A protein complex composed of the Fanconi anaemia (FA) proteins including A, C, E, G and F (FANCA-F). Functions in the activation of the downstream protein FANCD2 by monoubiquitylation, and is essential for protection against chromosome breakage.
43241	protein complex disassembly	P	The disaggregation of a protein complex into its constituent components. Protein complexes may have other associated non-protein prosthetic groups, such as nucleic acids, metal ions or carbohydrate groups.
43242	negative regulation of protein complex disassembly	P	Any process that stops, prevents, or reduces the frequency, rate or extent of protein complex disassembly, the disaggregation of a protein complex into its constituent components.
43243	positive regulation of protein complex disassembly	P	Any process that activates or increases the frequency, rate or extent of protein complex disassembly, the disaggregation of a protein complex into its constituent components.
43244	regulation of protein complex disassembly	P	Any process that modulates the frequency, rate or extent of protein complex disassembly, the disaggregation of a protein complex into its constituent components.
43245	extraorganismal space	C	The environmental space outside of an organism; this may be a host organism in the case of parasitic and symbiotic organisms.
43246	megasome	C	Large, cysteine proteinase rich lysosomes, often found in the amastigote (an intracytoplasmic, nonflagellated form of the parasite) stage of Leishmania species belonging to the mexicana complex.
43247	telomere maintenance in response to DNA damage	P	Any process that occur in response to the presence of critically short or damaged telomeres.
43248	proteasome assembly	P	The aggregation, arrangement and bonding together of a mature, active proteasome complex.
43249	erythrocyte maturation	P	A developmental process, independent of morphogenetic (shape) change, that is required for an erythrocyte to attain its fully functional state.
43250	sodium-dependent organic anion transmembrane transporter activity	F	Catalysis of the transfer of organic anions from one side of a membrane to the other, in a sodium dependent manner.
43251	sodium-dependent organic anion transport	P	The directed, sodium-dependent, movement of organic anions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
43252	sodium-independent organic anion transport	P	The directed, sodium-independent, movement of organic anions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
43253	chloroplast ribosome	C	A ribosome contained within a chloroplast.
43254	regulation of protein complex assembly	P	Any process that modulates the frequency, rate or extent of protein complex assembly.
43255	regulation of carbohydrate biosynthetic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of carbohydrates.
43256	laminin complex	C	A large, extracellular glycoprotein complex composed of three different polypeptide chains, alpha, beta and gamma. Provides an integral part of the structural scaffolding of basement membranes.
43257	laminin-8 complex	C	A laminin complex composed of alpha4, beta1 and gamma1 polypeptide chains.
43258	laminin-9 complex	C	A laminin complex composed of alpha4, beta2 and gamma1 polypeptide chains.
43259	laminin-10 complex	C	A laminin complex composed of alpha5, beta1 and gamma1 polypeptide chains.
43260	laminin-11 complex	C	A laminin complex composed of alpha5, beta2 and gamma1 polypeptide chains.
43261	laminin-12 complex	C	A laminin complex composed of alpha2, beta1 and gamma3 polypeptide chains.
43262	adenosine-diphosphatase activity	F	Catalysis of the reaction: ADP + H2O = AMP + phosphate.
43263	cellulosome	C	An extracellular multi-enzyme complex containing up to 11 different enzymes aligned on a non-catalytic scaffolding glycoprotein. Functions to hydrolyze cellulose.
43264	extracellular non-membrane-bounded organelle	C	Organized structure of distinctive morphology and function, not bounded by a lipid bilayer membrane and occurring outside the cell.
43265	ectoplasm	C	Granule free cytoplasm, lying immediately below the plasma membrane.
43266	regulation of potassium ion transport	P	Any process that modulates the frequency, rate or extent of the directed movement of potassium ions (K+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
43267	negative regulation of potassium ion transport	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of potassium ions (K+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
43268	positive regulation of potassium ion transport	P	Any process that activates or increases the frequency, rate or extent of the directed movement of potassium ions (K+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
43269	regulation of ion transport	P	Any process that modulates the frequency, rate or extent of the directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
43270	positive regulation of ion transport	P	Any process that activates or increases the frequency, rate or extent of the directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
43271	negative regulation of ion transport	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of charged atoms or small charged molecules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
43272	ethylene biosynthesis involved in jasmonic acid and ethylene-dependent systemic resistance	P	The chemical reactions and pathways resulting in the formation of ethylene (C2-H4, ethene), occurring as part of the process of jasmonic acid and ethylene-dependent systemic resistance.
43273	CTPase activity	F	Catalysis of the reaction: CTP + H2O = CDP + phosphate. May or may not be coupled to another reaction.
43274	phospholipase binding	F	Interacting selectively and non-covalently with any phospholipase, enzymes that catalyze of the hydrolysis of a glycerophospholipid.
43276	anoikis	P	Apoptosis triggered by inadequate or inappropriate adherence to substrate e.g. after disruption of the interactions between normal epithelial cells and the extracellular matrix.
43277	apoptotic cell clearance	P	The recognition and removal of an apoptotic cell by a neighboring cell or by a phagocyte.
43278	response to morphine	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a morphine stimulus. Morphine is an opioid alkaloid, isolated from opium, with a complex ring structure.
43279	response to alkaloid	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alkaloid stimulus. Alkaloids are a large group of nitrogenous substances found in naturally in plants, many of which have extracts that are pharmacologically active.
43280	positive regulation of cysteine-type endopeptidase activity involved in apoptotic process	P	Any process that activates or increases the activity of a cysteine-type endopeptidase involved in the apoptotic process.
43281	regulation of cysteine-type endopeptidase activity involved in apoptotic process	P	Any process that modulates the activity of a cysteine-type endopeptidase involved in apoptosis.
43282	pharyngeal muscle development	P	The process whose specific outcome is the progression of the pharyngeal muscle over time, from its formation to the mature structure. A pharyngeal muscle is any muscle that forms part of the pharynx.
43286	regulation of poly(3-hydroxyalkanoate) biosynthetic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of poly(3-hydroxyalkanoates), polyesters of 3-hydroxyacids produced as intracellular granules by a large variety of bacteria.
43287	poly(3-hydroxyalkanoate) binding	F	Interacting selectively and non-covalently with poly(3-hydroxyalkanoate)s, polyesters of 3-hydroxyacids produced as intracellular granules by a large variety of bacteria.
43288	apocarotenoid metabolic process	P	The chemical reactions and pathways involving apocarotenoids, a class of compounds derived from the oxidative cleavage of carotenoids, many of which are biologically important e.g. retinal and abscisic acid.
43289	apocarotenoid biosynthetic process	P	The chemical reactions and pathways resulting in the formation of apocarotenoids by the oxidative cleavage of carotenoids. Many apocarotenoids are biologically important e.g. retinal and abscisic acid.
43290	apocarotenoid catabolic process	P	The chemical reactions and pathways resulting in the breakdown of apocarotenoids, a class of compounds derived from the oxidative cleavage of carotenoids, many of which are biologically important e.g. retinal and abscisic acid.
43291	RAVE complex	C	A multisubunit complex that in Saccharomyces is composed of three subunits, Rav1p, Rav2p and Skp1p. Acts transiently to catalyze assembly of cytoplasmic V1, with membrane embedded V0 to form the V-ATPase holoenzyme.
43292	contractile fiber	C	Fibers, composed of actin, myosin, and associated proteins, found in cells of smooth or striated muscle.
43293	apoptosome	C	A multisubunit protein complex involved in the signaling phase of the apoptotic process. In mammals it is typically composed of seven Apaf-1 subunits bound to cytochrome c and caspase-9. A similar complex to promote apoptosis is formed from homologous gene products in other eukaryotic organisms.
43294	mitochondrial glutamate synthase complex (NADH)	C	A protein complex, found in the mitochondria, that in yeast consists of a large and a small subunit. Possesses glutamate synthase (NADH) activity.
43295	glutathione binding	F	Interacting selectively and non-covalently with glutathione; a tripeptide composed of the three amino acids cysteine, glutamic acid and glycine.
43296	apical junction complex	C	A functional unit located near the cell apex at the points of contact between epithelial cells, which in vertebrates is composed of the tight junction, the zonula adherens, and desmosomes and in some invertebrates, such as Drosophila, is composed of the subapical complex (SAC), the zonula adherens and the septate junction. Functions in the regulation of cell polarity, tissue integrity and intercellular adhesion and permeability.
43297	apical junction assembly	P	The formation of an apical junction, a functional unit located near the cell apex at the points of contact between epithelial cells composed of the tight junction, the zonula adherens junction and the desmosomes, by the aggregation, arrangement and bonding together of its constituents.
43299	leukocyte degranulation	P	The regulated exocytosis of secretory granules by a leukocyte.
43300	regulation of leukocyte degranulation	P	Any process that modulates the frequency, rate, or extent of leukocyte degranulation.
43301	negative regulation of leukocyte degranulation	P	Any process that stops, prevents, or reduces the rate of leukocyte degranulation.
43302	positive regulation of leukocyte degranulation	P	Any process that activates or increases the frequency, rate or extent of leukocyte degranulation.
43303	mast cell degranulation	P	The regulated exocytosis of secretory granules containing preformed mediators such as histamine, serotonin, and neutral proteases by a mast cell.
43304	regulation of mast cell degranulation	P	Any process that modulates the frequency, rate, or extent of mast cell degranulation.
43305	negative regulation of mast cell degranulation	P	Any process that stops, prevents, or reduces the rate of mast cell degranulation.
43306	positive regulation of mast cell degranulation	P	Any process that activates or increases the frequency, rate or extent of mast cell degranulation.
43307	eosinophil activation	P	The change in morphology and behavior of a eosinophil resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor.
43308	eosinophil degranulation	P	The regulated exocytosis of secretory granules containing preformed mediators such as major basic protein, eosinophil peroxidase, and eosinophil cationic protein by an eosinophil.
43309	regulation of eosinophil degranulation	P	Any process that modulates the frequency, rate, or extent of eosinophil degranulation.
43310	negative regulation of eosinophil degranulation	P	Any process that stops, prevents, or reduces the rate of eosinophil degranulation.
43311	positive regulation of eosinophil degranulation	P	Any process that activates or increases the frequency, rate or extent of eosinophil degranulation.
43312	neutrophil degranulation	P	The regulated exocytosis of secretory granules containing preformed mediators such as proteases, lipases, and inflammatory mediators by a neutrophil.
43313	regulation of neutrophil degranulation	P	Any process that modulates the frequency, rate, or extent of neutrophil degranulation.
43314	negative regulation of neutrophil degranulation	P	Any process that stops, prevents, or reduces the rate of neutrophil degranulation.
43315	positive regulation of neutrophil degranulation	P	Any process that activates or increases the frequency, rate or extent of neutrophil degranulation.
43316	cytotoxic T cell degranulation	P	The regulated exocytosis of secretory granules containing preformed mediators such as perforin and granzymes by a cytotoxic T cell.
43317	regulation of cytotoxic T cell degranulation	P	Any process that modulates the frequency, rate, or extent of cytotoxic T cell degranulation.
43318	negative regulation of cytotoxic T cell degranulation	P	Any process that stops, prevents, or reduces the rate of cytotoxic T cell degranulation.
43319	positive regulation of cytotoxic T cell degranulation	P	Any process that activates or increases the frequency, rate or extent of cytotoxic T cell degranulation.
43320	natural killer cell degranulation	P	The regulated exocytosis of secretory granules containing preformed mediators such as perforin and granzymes by a natural killer cell.
43321	regulation of natural killer cell degranulation	P	Any process that modulates the frequency, rate, or extent of natural killer cell degranulation.
43322	negative regulation of natural killer cell degranulation	P	Any process that stops, prevents, or reduces the rate of natural killer cell degranulation.
43323	positive regulation of natural killer cell degranulation	P	Any process that activates or increases the frequency, rate or extent of natural killer cell degranulation.
43324	pigment metabolic process involved in developmental pigmentation	P	The chemical reactions and pathways involving biological pigments e.g. melanin, occurring as part of the development of an organ or organism.
43325	phosphatidylinositol-3,4-bisphosphate binding	F	Interacting selectively and non-covalently with phosphatidylinositol-3,4-bisphosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 3' and 4' positions.
43326	chemotaxis to folate	P	The directed movement of a motile cell or organism in response to the presence of folate.
43327	chemotaxis to cAMP	P	The directed movement of a motile cell or organism in response to the presence of 3',5'-cAMP.
43328	protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway	P	The process of directing proteins towards the vacuole using signals contained within the protein, occurring that contributes to protein catabolism via the multivesicular body (MVB) pathway.
43329	protein targeting to membrane involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway	P	The process of directing proteins towards a membrane using signals contained within the protein, occurring that contributes to ubiquitin-dependent protein catabolism via the MVB pathway; the destruction of a protein or peptide covalently tagged with a ubiquitin, via the multivesicular body (MVB) sorting pathway.
43330	response to exogenous dsRNA	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an exogenous double-stranded RNA stimulus.
43331	response to dsRNA	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a double-stranded RNA stimulus.
43332	mating projection tip	C	The apex of the mating projection in unicellular fungi exposed to mating pheromone; site of polarized growth.
43333	2-octaprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity	F	Catalysis of the reaction: 2-octaprenyl-6-methoxy-1,4-benzoquinone + S-adenosyl-L-methionine = 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinone + S-adenosyl-L-homocysteine.
43334	2-hexaprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity	F	Catalysis of the reaction: 2-hexaprenyl-6-methoxy-1,4-benzoquinone + S-adenosyl-L-methionine = 2-hexaprenyl-3-methyl-6-methoxy-1,4-benzoquinone + S-adenosyl-L-homocysteine.
43335	protein unfolding	P	The process of assisting in the disassembly of non-covalent linkages in a protein or protein aggregate, often where the proteins are in a non-functional or denatured state.
43336	site-specific telomere resolvase activity	F	Catalysis of a site-specific breakage and reunion reaction that generates two hairpin telomeres from a replicated telomere substrate. Occurs via a two-step transesterification with a protein-DNA intermediate similar to that used by topoisomerases and site-specific recombinases.
43337	CDP-diacylglycerol-phosphatidylglycerol phosphatidyltransferase activity	F	Catalysis of the reaction: CDP-diacylglycerol + phosphatidylglycerol = CMP + diphosphatidylglycerol.
43338	CTP:2,3-di-O-geranylgeranyl-sn-glycero-1-phosphate cytidyltransferase activity	F	Catalysis of the reaction: CTP + 2,3-di-O-geranylgeranyl-sn-glycero-1-phosphate = CDP-2,3-di-O-geranylgeranyl-sn-glycerol.
43353	enucleate erythrocyte differentiation	P	The process in which a myeloid precursor cell acquires specialized features of an erythrocyte without a nucleus. An example of this process is found in Mus musculus.
43354	enucleate erythrocyte maturation	P	A developmental process, independent of morphogenetic (shape) change, that is required for an enucleate erythrocyte to attain its fully functional state. An enucleate erythrocyte is an erythrocyte without a nucleus.
43362	nucleate erythrocyte maturation	P	A developmental process, independent of morphogenetic (shape) change, that is required for a nucleate erythrocyte to attain its fully functional state. A nucleate erythrocyte is an erythrocyte with a nucleus.
43363	nucleate erythrocyte differentiation	P	The process in which a myeloid precursor cell acquires specializes features of an erythrocyte with a nucleus, as found in non-mammalian vertebrates such as birds.
43364	catalysis of free radical formation	F	Catalysis of a reaction that generates a free radical, a highly reactive molecule with an unsatisfied electron valence pair.
43365	[formate-C-acetyltransferase]-activating enzyme activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + dihydroflavodoxin + [formate C-acetyltransferase]-glycine = 5'-deoxyadenosine + L-methionine + flavodoxin semiquinone + [formate C-acetyltransferase]-glycin-2-yl radical.
43366	beta selection	P	The process in which successful recombination of a T cell receptor beta chain into a translatable protein coding sequence leads to rescue from apoptosis and subsequent proliferation of an immature T cell.
43367	CD4-positive, alpha-beta T cell differentiation	P	The process in which a relatively unspecialized T cell acquires specialized features of a mature CD4-positive, alpha-beta T cell.
43368	positive T cell selection	P	The process of sparing immature T cells which react with self-MHC protein complexes with low affinity levels from apoptotic death.
43369	CD4-positive or CD8-positive, alpha-beta T cell lineage commitment	P	The process in which an immature T cell commits to CD4-positive T cell lineage or the CD8-positive lineage of alpha-beta T cells.
43370	regulation of CD4-positive, alpha-beta T cell differentiation	P	Any process that modulates the frequency, rate, or extent of CD4-positive, alpha-beta T cell differentiation.
43371	negative regulation of CD4-positive, alpha-beta T cell differentiation	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of CD4-positive, alpha-beta T cell differentiation.
43372	positive regulation of CD4-positive, alpha-beta T cell differentiation	P	Any process that activates or increases the frequency, rate or extent of CD4-positive, alpha-beta T cell differentiation.
43373	CD4-positive, alpha-beta T cell lineage commitment	P	The process in which an immature T cell becomes committed to becoming a CD4-positive, alpha-beta T cell.
43374	CD8-positive, alpha-beta T cell differentiation	P	The process in which a relatively unspecialized T cell acquires specialized features of a mature CD8-positive, alpha-beta T cell.
43375	CD8-positive, alpha-beta T cell lineage commitment	P	The process in which an immature T cell becomes committed to becoming a CD8-positive, alpha-beta T cell.
43376	regulation of CD8-positive, alpha-beta T cell differentiation	P	Any process that modulates the frequency, rate, or extent of CD8-positive, alpha-beta T cell differentiation.
43377	negative regulation of CD8-positive, alpha-beta T cell differentiation	P	Any process that stops, prevents, or reduces the rate of CD8-positive, alpha-beta T cell differentiation.
43378	positive regulation of CD8-positive, alpha-beta T cell differentiation	P	Any process that activates or increases the frequency, rate or extent of CD8-positive, alpha-beta T cell differentiation.
43379	memory T cell differentiation	P	The process in which a newly activated T cell acquires specialized features of a memory T cell.
43380	regulation of memory T cell differentiation	P	Any process that modulates the frequency, rate, or extent of memory T cell differentiation.
43381	negative regulation of memory T cell differentiation	P	Any process that stops, prevents, or reduces the rate of memory T cell differentiation.
43382	positive regulation of memory T cell differentiation	P	Any process that activates or increases the frequency, rate or extent of memory T cell differentiation.
43383	negative T cell selection	P	The process of elimination of immature T cells which react strongly with self-antigens.
43384	pre-T cell receptor complex	C	A receptor complex found on immature T cells consisting of a T cell receptor beta chain and the pre-TCR-alpha chain, along with additional signaling components including CD3 family members and additional signaling proteins.
43385	mycotoxin metabolic process	P	The chemical reactions and pathways involving a mycotoxin, any poisonous substance produced by a fungus.
43386	mycotoxin biosynthetic process	P	The chemical reactions and pathways resulting in the formation of a mycotoxin, any poisonous substance produced by a fungus.
43387	mycotoxin catabolic process	P	The chemical reactions and pathways resulting in the breakdown of a mycotoxin, any poisonous substance produced by a fungus.
43388	positive regulation of DNA binding	P	Any process that increases the frequency, rate or extent of DNA binding. DNA binding is any process in which a gene product interacts selectively with DNA (deoxyribonucleic acid).
43390	aflatoxin B1 metabolic process	P	The chemical reactions and pathways involving aflatoxin B1, a potent hepatotoxic and hepatocarcinogenic mycotoxin produced by various species from the Aspergillus group of fungi.
43391	aflatoxin B2 metabolic process	P	The chemical reactions and pathways involving aflatoxin B2, a mycotoxin produced by the fungal species Aspergillus flavus, Aspergillus parasiticus and Aspergillus nomius.
43392	negative regulation of DNA binding	P	Any process that stops or reduces the frequency, rate or extent of DNA binding. DNA binding is any process in which a gene product interacts selectively with DNA (deoxyribonucleic acid).
43393	regulation of protein binding	P	Any process that modulates the frequency, rate or extent of protein binding.
43394	proteoglycan binding	F	Interacting selectively and non-covalently with a proteoglycan, any glycoprotein in which the carbohydrate units are glycosaminoglycans.
43395	heparan sulfate proteoglycan binding	F	Interacting selectively and non-covalently with a heparan sulfate proteoglycan, any proteoglycan containing heparan sulfate as the glycosaminoglycan carbohydrate unit.
43396	corticotropin-releasing hormone secretion	P	The regulated release of corticotropin-releasing hormone (CRH), a polypeptide hormone involved in the stress response. CRH is produced by the hypothalamus and stimulates corticotropic cells of the anterior lobe of the pituitary to produce corticotropic hormone (CTH) and other biologically active substances e.g. 2-endorphin, release of CRH is affected by serum levels of cortisol, by stress and by the sleep/wake cycle.
43397	regulation of corticotropin-releasing hormone secretion	P	Any process that modulates the frequency, rate or extent of corticotropin-releasing hormone secretion.
43398	HLH domain binding	F	Interacting selectively and non-covalently with Helix Loop Helix, a domain of 40-50 residues that occurs in specific DNA-binding proteins that act as transcription factors. The domain is formed of two amphipathic helices joined by a variable length linker region that can form a loop and it mediates protein dimerization.
43399	tRNA A64-2'-O-ribosylphosphate transferase activity	F	Catalysis of the transfer of a phosphoribosyl group from 5'-phosphoribosyl-1'-pyrophosphate to position 64 of initiator tRNA.
43400	cortisol secretion	P	The regulated release of cortisol, a steroid hormone that in humans is the major circulating hormone of the cortex, or outer layer, of the adrenal gland.
43401	steroid hormone mediated signaling pathway	P	A series of molecular signals mediated by a steroid hormone binding to a receptor.
43402	glucocorticoid mediated signaling pathway	P	A series of molecular signals mediated by the detection of a glucocorticoid hormone.
43403	skeletal muscle tissue regeneration	P	The regrowth of skeletal muscle tissue to repair injured or damaged muscle fibers in the postnatal stage.
43404	corticotropin-releasing hormone receptor activity	F	Combining with corticotropin-releasing hormone and transmitting the signal to initiate a change in cell activity.
43405	regulation of MAP kinase activity	P	Any process that modulates the frequency, rate or extent of MAP kinase activity.
43406	positive regulation of MAP kinase activity	P	Any process that activates or increases the frequency, rate or extent of MAP kinase activity.
43407	negative regulation of MAP kinase activity	P	Any process that stops, prevents, or reduces the frequency, rate or extent of MAP kinase activity.
43408	regulation of MAPK cascade	P	Any process that modulates the frequency, rate or extent of signal transduction mediated by the MAP kinase (MAPK) cascade.
43409	negative regulation of MAPK cascade	P	Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the MAPKKK cascade.
43410	positive regulation of MAPK cascade	P	Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the MAPK cascade.
43412	macromolecule modification	P	The covalent alteration of one or more monomeric units in a polypeptide, polynucleotide, polysaccharide, or other biological macromolecule, resulting in a change in its properties.
43413	macromolecule glycosylation	P	The covalent attachment of a glycosyl residue to one or more monomeric units in a polypeptide, polynucleotide, polysaccharide, or other biological macromolecule.
43414	macromolecule methylation	P	The covalent attachment of a methyl residue to one or more monomeric units in a polypeptide, polynucleotide, polysaccharide, or other biological macromolecule.
43415	positive regulation of skeletal muscle tissue regeneration	P	Any process that activates or increase the rate of skeletal muscle regeneration.
43416	regulation of skeletal muscle tissue regeneration	P	Any process that modulates the frequency, rate or extent of skeletal muscle.
43417	negative regulation of skeletal muscle tissue regeneration	P	Any process that stops, prevents, or reduces the frequency, rate or extent of skeletal muscle regeneration.
43418	homocysteine catabolic process	P	The chemical reactions and pathways resulting in the breakdown of homocysteine, the amino acid alpha-amino-gamma-mercaptobutanoic acid.
43419	urea catabolic process	P	The chemical reactions and pathways resulting in the breakdown of urea, the water soluble compound O=C-(NH2)2.
43420	anthranilate metabolic process	P	The chemical reactions and pathways involving anthranilate (2-aminobenzoate).
43421	anthranilate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of anthranilate (2-aminobenzoate).
43422	protein kinase B binding	F	Interacting selectively and non-covalently with protein kinase B, an intracellular kinase that is important in regulating glucose metabolism.
43423	3-phosphoinositide-dependent protein kinase binding	F	Interacting selectively and non-covalently with a 3-phosphoinositide-dependent protein kinase.
43424	protein histidine kinase binding	F	Interacting selectively and non-covalently with protein histidine kinase.
43425	bHLH transcription factor binding	F	Interacting selectively and non-covalently with any of the basic Helix-Loop-Helix (bHLH) superfamily of transcription factors, important regulatory components in transcriptional networks of many developmental pathways.
43426	MRF binding	F	Interacting selectively and non-covalently with Myogenic Regulatory Factor (MRF), a member of the basic Helix-Loop-Helix (bHLH) superfamily of transcription factors.
43427	carbon fixation by 3-hydroxypropionate cycle	P	An autotrophic carbon dioxide fixation pathway by which two molecules of carbon dioxide are fixed to form glyoxylate. Acetyl coenzyme A (acetyl-CoA) is assumed to be converted to malate, and two CO2 molecules are thereby fixed. Malyl-CoA is thought to be cleaved to acetyl-CoA, the starting molecule, and glyoxylate, the carbon fixation product.
43428	2-heptaprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity	F	Catalysis of the reaction: 2-heptaprenyl-6-methoxy-1,4-benzoquinone + S-adenosyl-L-methionine = 2-heptaprenyl-3-methyl-6-methoxy-1,4-benzoquinone + S-adenosyl-L-homocysteine.
43429	2-nonaprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity	F	Catalysis of the reaction: 2-nonaprenyl-6-methoxy-1,4-benzoquinone + S-adenosyl-L-methionine = 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinone + S-adenosyl-L-homocysteine.
43430	2-decaprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity	F	Catalysis of the reaction: 2-decaprenyl-6-methoxy-1,4-benzoquinone + S-adenosyl-L-methionine = 2-decaprenyl-3-methyl-6-methoxy-1,4-benzoquinone + S-adenosyl-L-homocysteine.
43431	2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinone methyltransferase activity	F	Catalysis of the reaction: 2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinol + S-adenosyl-L-methionine = ubiquinol + S-adenosyl-L-homocysteine.
43433	negative regulation of sequence-specific DNA binding transcription factor activity	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of a transcription factor, any factor involved in the initiation or regulation of transcription.
43434	response to peptide hormone	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptide hormone stimulus. A peptide hormone is any of a class of peptides that are secreted into the blood stream and have endocrine functions in living animals.
43435	response to corticotropin-releasing hormone	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a corticotropin-releasing hormone stimulus. Corticotropin-releasing hormone is a peptide hormone involved in the stress response.
43436	oxoacid metabolic process	P	The chemical reactions and pathways involving any oxoacid; an oxoacid is a compound which contains oxygen, at least one other element, and at least one hydrogen bound to oxygen, and which produces a conjugate base by loss of positive hydrogen ion(s) (hydrons).
43438	acetoacetic acid metabolic process	P	The chemical reactions and pathways involving acetoacetic acid, 3-oxobutanoic acid; the empirical formula is C4H6O3 or CH3COCH2COOH.
43441	acetoacetic acid biosynthetic process	P	The chemical reactions and pathways resulting in the formation of acetoacetic acid, a beta-keto acid of the keto acid group, empirical formula is C4H6O3 or CH3COCH2COOH.
43442	acetoacetic acid catabolic process	P	The chemical reactions and pathways resulting in the breakdown of acetoacetic acid, a beta-keto acid of the keto acid group, empirical formula is C4H6O3 or CH3COCH2COOH.
43443	acetone metabolic process	P	The chemical reactions and pathways involving acetone, propan-2-one.
43444	acetone catabolic process	P	The chemical reactions and pathways resulting in the breakdown of acetone, propan-2-one.
43445	acetone biosynthetic process	P	The chemical reactions and pathways resulting in the formation of acetone, propan-2-one.
43446	cellular alkane metabolic process	P	The chemical reactions and pathways involving an alkane, any acyclic branched or unbranched hydrocarbon having the general formula CnH2n+2, as carried out by individual cells.
43447	alkane biosynthetic process	P	The chemical reactions and pathways resulting in the formation of an alkane, any acyclic branched or unbranched hydrocarbon having the general formula CnH2n+2.
43448	alkane catabolic process	P	The chemical reactions and pathways resulting in the breakdown of an alkane, any acyclic branched or unbranched hydrocarbon having the general formula CnH2n+2.
43449	cellular alkene metabolic process	P	The chemical reactions and pathways involving an alkene, any acyclic branched or unbranched hydrocarbon having one carbon-carbon double bond and the general formula CnH2n, as carried out by individual cells.
43450	alkene biosynthetic process	P	The chemical reactions and pathways resulting in the formation of an alkene, any acyclic branched or unbranched hydrocarbon having one carbon-carbon double bond and the general formula CnH2n.
43451	alkene catabolic process	P	The chemical reactions and pathways resulting in the breakdown of an alkene, any acyclic branched or unbranched hydrocarbon having one carbon-carbon double bond and the general formula CnH2n.
43452	cellular alkyne metabolic process	P	The chemical reactions and pathways involving an alkyne, any cyclic branched or unbranched hydrocarbon having a carbon-carbon triple bond and the general formula CnH2n-2, as carried out by individual cells.
43453	alkyne biosynthetic process	P	The chemical reactions and pathways resulting in the formation of an alkyne, any cyclic branched or unbranched hydrocarbon having a carbon-carbon triple bond and the general formula CnH2n-2.
43454	alkyne catabolic process	P	The chemical reactions and pathways resulting in the breakdown of an alkyne, any cyclic branched or unbranched hydrocarbons having a carbon-carbon triple bond and the general formula CnH2n-2.
43455	regulation of secondary metabolic process	P	Any process that modulates the frequency, rate or extent of secondary metabolism, the chemical reactions and pathways involving compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon.
43456	regulation of pentose-phosphate shunt	P	Any process that modulates the frequency, rate or extent of the pentose-phosphate shunt, the process in which glucose is oxidized, coupled to NADPH synthesis.
43457	regulation of cellular respiration	P	Any process that modulates the frequency, rate or extent of cellular respiration, the enzymatic release of energy from organic compounds.
43458	ethanol biosynthetic process involved in glucose fermentation to ethanol	P	The chemical reactions and pathways resulting in the formation of ethanol, CH3-CH2-OH, as part of the process of glucose catabolism to ethanol, CO2 and ATP.
43461	proton-transporting ATP synthase complex assembly	P	The aggregation, arrangement and bonding together of a proton-transporting ATP synthase (also known as F-type ATPase), a two-sector ATPase found in the inner membrane of mitochondria and chloroplasts, and in bacterial plasma membranes.
43462	regulation of ATPase activity	P	Any process that modulates the rate of ATP hydrolysis by an ATPase.
43463	regulation of rhamnose catabolic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of rhamnose, the hexose 6-deoxy-L-mannose.
43464	malolactic fermentation	P	The anaerobic enzymatic conversion of L-malate to L-lactate and carbon dioxide, yielding energy in the form of ATP.
43465	regulation of fermentation	P	Any process that modulates the frequency, rate or extent of fermentation, the anaerobic enzymatic conversion of organic compounds, especially carbohydrates, to other compounds, especially to ethyl alcohol, resulting in energy in the form of adenosine triphosphate (ATP).
43466	pyrimidine nucleobase fermentation	P	The anaerobic conversion of pyrimidine nucleobases, yielding energy in the form of ATP.
43467	regulation of generation of precursor metabolites and energy	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of precursor metabolites, substances from which energy is derived, and the processes involved in the liberation of energy from these substances.
43468	regulation of fucose catabolic process	P	Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of fucose.
43469	regulation of D-xylose catabolic process	P	Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of xylose.
43470	regulation of carbohydrate catabolic process	P	Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of carbohydrates.
43471	regulation of cellular carbohydrate catabolic process	P	Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of carbohydrates, carried out by individual cells.
43472	IgD binding	F	Interacting selectively and non-covalently with an immunoglobulin of a D isotype.
43473	pigmentation	P	The accumulation of pigment in an organism, tissue or cell, either by increased deposition or by increased number of cells.
43474	pigment metabolic process involved in pigmentation	P	The chemical reactions and pathways involving a pigment, any general or particular coloring matter in living organisms, resulting in the deposition or aggregation of pigment in an organism, tissue or cell.
43475	pigment metabolic process involved in pigment accumulation	P	The chemical reactions and pathways involving a pigment, any general or particular coloring matter in living organisms, as part of the accumulation of pigment.
43476	pigment accumulation	P	The aggregation of coloring matter in a particular location in an organism, tissue or cell, occurring in response to some external stimulus.
43477	pigment biosynthetic process involved in pigment accumulation	P	The chemical reactions and pathways resulting in the formation of a pigment, any general or particular coloring matter in living organisms, resulting in pigment accumulation.
43478	pigment accumulation in response to UV light	P	The aggregation of coloring matter in a particular location in an organism, tissue or cell, occurring in response to a UV light stimulus.
43479	pigment accumulation in tissues in response to UV light	P	The aggregation of coloring matter in a particular location in a tissue, occurring in response to a UV light stimulus.
43480	pigment accumulation in tissues	P	The aggregation of coloring matter in a particular location in a tissue, occurring in response to an external stimulus.
43481	anthocyanin accumulation in tissues in response to UV light	P	The aggregation of the pigment anthocyanin in a particular location in a tissue, occurring in response to a UV light stimulus.
43482	cellular pigment accumulation	P	The aggregation of coloring matter in a particular location in a cell, occurring in response to some external stimulus.
43483	anthocyanin biosynthetic process involved in anthocyanin accumulation in response to UV light	P	The chemical reactions and pathways resulting in the formation of the pigment anthocyanin, contributing to anthocyanin accumulation in a tissue in response to a UV light stimulus.
43484	regulation of RNA splicing	P	Any process that modulates the frequency, rate or extent of RNA splicing, the process of removing sections of the primary RNA transcript to remove sequences not present in the mature form of the RNA and joining the remaining sections to form the mature form of the RNA.
43485	endosome to pigment granule transport	P	The directed movement of substances from endosomes to pigment granules.
43486	histone exchange	P	The replacement, within chromatin, of resident histones or histone subunits with alternative, sometimes variant, histones or subunits.
43487	regulation of RNA stability	P	Any process that modulates the propensity of RNA molecules to degradation. Includes processes that both stabilize and destabilize RNAs.
43488	regulation of mRNA stability	P	Any process that modulates the propensity of mRNA molecules to degradation. Includes processes that both stabilize and destabilize mRNAs.
43489	RNA stabilization	P	Prevention of degradation of RNA molecules.
43490	malate-aspartate shuttle	P	The process of transferring reducing equivalents from the cytosol into the mitochondria; NADH is used to synthesise malate in the cytosol; this compound is then transported into the mitochondria where it is converted to oxaloacetate using NADH, the oxaloacetate reacts with gluamate to form aspartate, and the aspartate then returns to the cytosol to complete the cycle.
43491	protein kinase B signaling	P	A series of reactions, mediated by the intracellular serine/threonine kinase protein kinase B (also called AKT), which occurs as a result of a single trigger reaction or compound.
43492	ATPase activity, coupled to movement of substances	F	Catalysis of the reaction: ATP + H2O = ADP + phosphate, to directly drive the transport of a substance.
43493	viral terminase complex	C	A complex of a large and small subunit which catalyze the packaging of DNA into viral heads. Note that not all viral terminases have this structure, some exist as single polypeptides.
43494	CLRC ubiquitin ligase complex	C	An cullin-dependent E3 ubiquitin ligase/histone H3-K9 methyltransferase complex essential for heterochromatin assembly by RNAi.
43495	protein anchor	F	Interacting selectively and non-covalently with both a protein or protein complex and a membrane, in order to maintain the localization of the protein at a specific location on the membrane.
43496	regulation of protein homodimerization activity	P	Any process that modulates the frequency, rate or extent of protein homodimerization, interacting selectively with an identical protein to form a homodimer.
43497	regulation of protein heterodimerization activity	P	Any process that modulates the frequency, rate or extent of protein heterodimerization, interacting selectively with a nonidentical protein to form a heterodimer.
43500	muscle adaptation	P	A process in which muscle adapts, with consequent modifications to structural and/or functional phenotypes, in response to a stimulus. Stimuli include contractile activity, loading conditions, substrate supply, and environmental factors. These adaptive events occur in both muscle fibers and associated structures (motoneurons and capillaries), and they involve alterations in regulatory mechanisms, contractile properties and metabolic capacities.
43501	skeletal muscle adaptation	P	Any process in which skeletal muscles change their phenotypic profiles in response to altered functional demands and a variety of signals.
43502	regulation of muscle adaptation	P	Any process that modulates the frequency, rate or extent of muscle adaptation.
43503	skeletal muscle fiber adaptation	P	Any process in which the skeletal muscle fibers change their phenotypic profiles in response to altered functional demands and a variety of signals. Muscle fibers are formed by the maturation of myotubes. They can be classed as slow, intermediate/fast or fast.
43504	mitochondrial DNA repair	P	The process of restoring mitochondrial DNA after damage.
43505	CENP-A containing nucleosome	C	A form of nucleosome located only at the centromere, in which the histone H3 is replaced by the variant form CENP-A (sometimes known as CenH3).
43506	regulation of JUN kinase activity	P	Any process that modulates the frequency, rate or extent of JUN kinase activity.
43507	positive regulation of JUN kinase activity	P	Any process that activates or increases the frequency, rate or extent of JUN kinase activity.
43508	negative regulation of JUN kinase activity	P	Any process that stops, prevents, or reduces the frequency, rate or extent of JUN kinase activity.
43509	activin A complex	C	A nonsteroidal regulator, composed of two covalently linked inhibin beta-A subunits (sometimes known as activin beta-A or activin/inhibin beta-A).
43510	activin B complex	C	A nonsteroidal regulator, composed of two covalently linked inhibin beta-B subunits (sometimes known as activin beta-B or activin/inhibin beta-B).
43511	inhibin complex	C	Heterodimeric hormone composed of an inhibin alpha subunit complexed with either an inhibin beta-A subunit, to form inhibin A, or an inhibin beta-B subunit, to form inhibin B.
43512	inhibin A complex	C	Heterodimeric hormone composed of an inhibin alpha subunit complexed with an inhibin beta-A subunit.
43513	inhibin B complex	C	Heterodimeric hormone composed of an inhibin alpha subunit complexed with an inhibin beta-B subunit.
43514	interleukin-12 complex	C	A protein complex that is composed of an interleukin-12 alpha (p35, product of the IL12A gene) and an interleukin-12 beta subunit (p40, product of the IL12B gene) and is secreted into the extracellular space.
43515	kinetochore binding	F	Interacting selectively and non-covalently with a kinetochore, a proteinaceous structure on a condensed chromosome, beside the centromere, to which the spindle fibers are attached.
43516	regulation of DNA damage response, signal transduction by p53 class mediator	P	Any process that modulates the frequency, rate or extent of the cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage.
43517	positive regulation of DNA damage response, signal transduction by p53 class mediator	P	Any process that activates, maintains or increases the rate of the cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage.
43518	negative regulation of DNA damage response, signal transduction by p53 class mediator	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage.
43519	regulation of myosin II filament organization	P	Any process that modulates the frequency, rate or extent of the assembly, arrangement of constituent parts, or disassembly of a bipolar filament composed of myosin II molecules.
43520	regulation of myosin II filament assembly	P	Any process that modulates the frequency, rate or extent of the formation of a bipolar filament composed of myosin II molecules.
43521	regulation of myosin II filament disassembly	P	Any process that modulates the frequency, rate or extent of the disassembly of a bipolar filament composed of myosin II molecules.
43522	leucine zipper domain binding	F	Interacting selectively and non-covalently with a leucine zipper domain, a protein secondary structure exhibiting a periodic repetition of leucine residues at every seventh position over a distance covering eight helical turns.
43523	regulation of neuron apoptotic process	P	Any process that modulates the occurrence or rate of cell death by apoptotic process in neurons.
43524	negative regulation of neuron apoptotic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of cell death by apoptotic process in neurons.
43525	positive regulation of neuron apoptotic process	P	Any process that activates or increases the frequency, rate or extent of cell death of neurons by apoptotic process.
43527	tRNA methyltransferase complex	C	A multimeric protein complex involved in the methylation of specific nucleotides in tRNA.
43528	tRNA (m2G10) methyltransferase complex	C	A protein complex required for the methylation of the guanosine nucleotide at position 10 (m2G10) in tRNA. In S. cerevisiae, this complex consists of at least two subunits, Trm11p and Trm112p.
43529	GET complex	C	A multisubunit complex involved in ER/Golgi trafficking (Golgi to ER Traffic). In yeast, includes Get1p, Get2p and Get3p proteins.
43530	adenosine 5'-monophosphoramidase activity	F	Catalysis of the reaction: adenosine 5'-monophosphoramidate = AMP + NH2. Other substrates include AMP-morpholidate, AMP-N-alanine methyl ester and AMP-alpha-acetyl lysine methyl ester.
43531	ADP binding	F	Interacting selectively and non-covalently with ADP, adenosine 5'-diphosphate.
43532	angiostatin binding	F	Interacting selectively and non-covalently with angiostatin, a proteolytic product of plasminogen or plasmin containing at least one intact kringle domain, and which is an inhibitor of angiogenesis.
43533	inositol 1,3,4,5 tetrakisphosphate binding	F	Interacting selectively and non-covalently with inositol 1,3,4,5 tetrakisphosphate.
43534	blood vessel endothelial cell migration	P	The orderly movement of an endothelial cell into the extracellular matrix in order to form new blood vessels during angiogenesis.
43535	regulation of blood vessel endothelial cell migration	P	Any process that modulates the frequency, rate or extent of the migration of the endothelial cells of blood vessels.
43536	positive regulation of blood vessel endothelial cell migration	P	Any process that activates or increases the frequency, rate or extent of the migration of the endothelial cells of blood vessels.
43537	negative regulation of blood vessel endothelial cell migration	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the migration of the endothelial cells of blood vessels.
43538	regulation of actin phosphorylation	P	Any process that modulates the frequency, rate or extent of the transfer of one or more phosphate groups to an actin molecule.
43539	protein serine/threonine kinase activator activity	F	Binds to and increases the activity of a protein serine/threonine kinase.
43540	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex	C	A homodimeric, bifunctional enzyme complex which catalyzes the synthesis and degradation of fructose 2,6-bisphosphate, and is required for both glycolysis and gluconeogenesis.
43541	UDP-N-acetylglucosamine transferase complex	C	A multienzyme, heterooligomeric complex involved in dolichyl-linked oligosaccharide synthesis. In yeast the complex is composed of Alg7p, which catalyzes the first step (GlcNAc1-PP-Dol from dolichol-phosphate and UDP-GlcNAc), and Alg13p plus Alg14p, the catalytic and anchoring subunits respectively, which together catalyze the second step (GlcNAc2-PP-dolichol from GlcNAc1-PP-Dol and UDP-GlcNAc) of dolichyl-linked oligosaccharide synthesis.
43542	endothelial cell migration	P	The orderly movement of an endothelial cell into the extracellular matrix to form an endothelium.
43543	protein acylation	P	The addition of an acyl group, any group or radical of the form RCO- where R is an organic group, to a protein amino acid.
43544	lipoamide binding	F	Interacting selectively and non-covalently with lipoamide, the functional form of lipoic acid in which the carboxyl group is attached to protein by an amide linkage to a lysine amino group.
43545	molybdopterin cofactor metabolic process	P	The chemical reactions and pathways involving the molybdopterin cofactor (Moco), essential for the catalytic activity of some enzymes, e.g. sulfite oxidase, xanthine dehydrogenase, and aldehyde oxidase. The cofactor consists of a mononuclear molybdenum (Mo-molybdopterin) or tungsten ion (W-molybdopterin) coordinated by one or two molybdopterin ligands.
43546	molybdopterin cofactor binding	F	Interacting selectively and non-covalently with the molybdopterin cofactor (Moco), essential for the catalytic activity of some enzymes, e.g. sulfite oxidase, xanthine dehydrogenase, and aldehyde oxidase. The cofactor consists of a mononuclear molybdenum (Mo-molybdopterin) or tungsten ion (W-molybdopterin) coordinated by one or two molybdopterin ligands.
43547	positive regulation of GTPase activity	P	Any process that activates or increases the activity of a GTPase.
43548	phosphatidylinositol 3-kinase binding	F	Interacting selectively and non-covalently with a phosphatidylinositol 3-kinase, any enzyme that catalyzes the addition of a phosphate group to an inositol lipid at the 3' position of the inositol ring.
43549	regulation of kinase activity	P	Any process that modulates the frequency, rate or extent of kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule.
43550	regulation of lipid kinase activity	P	Any process that modulates the frequency, rate or extent of lipid kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a simple or complex lipid.
43551	regulation of phosphatidylinositol 3-kinase activity	P	Any process that modulates the frequency, rate or extent of phosphatidylinositol 3-kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to an inositol lipid at the 3' position of the inositol ring.
43552	positive regulation of phosphatidylinositol 3-kinase activity	P	Any process that activates or increases the frequency, rate or extent of phosphatidylinositol 3-kinase activity.
43553	negative regulation of phosphatidylinositol 3-kinase activity	P	Any process that stops, prevents, or reduces the frequency, rate or extent of phosphatidylinositol 3-kinase activity.
43554	aerobic respiration, using arsenite as electron donor	P	The oxidation of arsenite to arsenate, using oxygen (O2) as the electron acceptor. Arsenite oxidase provides electrons to an electron carrier which transfers them to oxygen utilizing respiratory systems.
43555	regulation of translation in response to stress	P	Modulation of the frequency, rate or extent of translation as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).
43556	regulation of translation in response to oxidative stress	P	Any process that modulates the frequency, rate or extent of translation as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
43557	regulation of translation in response to osmotic stress	P	Any process that modulates the frequency, rate or extent of the frequency, rate or extent of translation as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell.
43558	regulation of translational initiation in response to stress	P	Any process that modulates the frequency, rate or extent of translation initiation, as a result of a stimulus indicating the organism is under stress.
43559	insulin binding	F	Interacting selectively and non-covalently with insulin, a polypeptide hormone produced by the islets of Langerhans of the pancreas in mammals, and by the homologous organs of other organisms.
43560	insulin receptor substrate binding	F	Interacting selectively and non-covalently with any of the insulin receptor substrate (IRS) proteins, adaptor proteins that bind to the transphosphorylated insulin and insulin-like growth factor receptors, are themselves phosphorylated and in turn recruit SH2 domain-containing signaling molecules to form a productive signaling complex.
43561	regulation of translational initiation in response to osmotic stress	P	Any process that modulates the frequency, rate or extent of translation initiation, as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell.
43562	cellular response to nitrogen levels	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of inorganic nitrogen.
43563	odorant transporter activity	F	Enables the directed movement of odorants, any substance capable of stimulating the sense of smell, into, out of or within a cell, or between cells.
43564	Ku70:Ku80 complex	C	Heterodimeric protein complex composed of a 70 kDa and a 80 kDa subunit, binds DNA through a channel formed by the heterodimer. Functions in DNA double stranded break repair, chromosome maintenance, transcription regulation, V(D)J recombination, and activation of DNA-PK.
43565	sequence-specific DNA binding	F	Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
43566	structure-specific DNA binding	F	Interacting selectively and non-covalently with DNA of a specific structure or configuration e.g. triplex DNA binding or bent DNA binding.
43567	regulation of insulin-like growth factor receptor signaling pathway	P	Any process that modulates the frequency, rate or extent of insulin-like growth factor receptor signaling.
43568	positive regulation of insulin-like growth factor receptor signaling pathway	P	Any process that increases the frequency, rate or extent of insulin-like growth factor receptor signaling.
43569	negative regulation of insulin-like growth factor receptor signaling pathway	P	Any process that stops, prevents, or reduces the frequency, rate or extent of insulin-like growth factor receptor signaling.
43570	maintenance of DNA repeat elements	P	Any process involved in sustaining the fidelity and copy number of DNA repeat elements.
43571	maintenance of CRISPR repeat elements	P	Any process involved in sustaining CRISPR repeat clusters, including capture of new spacer elements, expansion or contraction of clusters, propagation of the leader sequence and repeat clusters within a genome, transfer of repeat clusters and CRISPR-associated (cas) genes to new genomes, transcription of the CRISPR repeat arrays into RNA and processing, and interaction of CRISPR/cas loci with the host genome. CRISPR (clustered regularly interspaced short palindromic repeat) elements are a family of sequence elements containing multiple direct repeats of 24-48 bp with weak dyad symmetry which are separated by regularly sized nonrepetitive spacer sequences.
43572	plastid fission	P	The creation of two or more plastids by division of one plastid. A plastid is any member of a family of organelles found in the cytoplasm of plants and some protists, which are membrane-bounded and contain DNA.
43573	leucoplast fission	P	The creation of two or more leucoplasts by division of one leucoplast. A leucoplast is a colorless plastid involved in the synthesis of monoterpenes.
43574	peroxisomal transport	P	Transport of substances into, out of or within a peroxisome, a small, membrane-bounded organelle that uses dioxygen (O2) to oxidize organic molecules.
43575	detection of osmotic stimulus	P	The series of events in which a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell is received and converted into a molecular signal.
43576	regulation of respiratory gaseous exchange	P	Any process that modulates the frequency, rate or extent of the process of gaseous exchange between an organism and its environment.
43577	chemotropism	P	The movement of an organism, or part of an organism, in response to an external chemical gradient, usually toward or away from it.
43578	nuclear matrix organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear matrix, the dense fibrillar network lying on the inner side of the nuclear membrane.
43579	elaioplast organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an elaioplast, a leucoplast in which oil is stored.
43580	periplasmic space organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the periplasmic space, the region between the inner (cytoplasmic) and outer membrane in Gram-negative bacteria, or the inner membrane and cell wall in fungi.
43582	sporangium development	P	The process whose specific outcome is the progression of the sporangium over time, from its formation to the mature structure. A sporangium is a structure producing and containing spores.
43583	ear development	P	The process whose specific outcome is the progression of the ear over time, from its formation to the mature structure. The ear is the sense organ in vertebrates that is specialized for the detection of sound, and the maintenance of balance. Includes the outer ear and middle ear, which collect and transmit sound waves; and the inner ear, which contains the organs of balance and (except in fish) hearing. Also includes the pinna, the visible part of the outer ear, present in some mammals.
43584	nose development	P	The process whose specific outcome is the progression of the nose over time, from its formation to the mature structure. The nose is the specialized structure of the face that serves as the organ of the sense of smell and as part of the respiratory system. Includes the nasi externus (external nose) and cavitas nasi (nasal cavity).
43585	nose morphogenesis	P	The process in which the anatomical structures of the nose are generated and organized. The nose is the specialized structure of the face that serves as the organ of the sense of smell and as part of the respiratory system. Includes the nasi externus (external nose) and cavitas nasi (nasal cavity).
43586	tongue development	P	The process whose specific outcome is the progression of the tongue over time, from its formation to the mature structure. The tongue is the movable, muscular organ on the floor of the mouth of most vertebrates, in many other mammals is the principal organ of taste, aids in the prehension of food, in swallowing, and in modifying the voice as in speech.
43587	tongue morphogenesis	P	The process in which the anatomical structures of the tongue are generated and organized. The tongue is the movable, muscular organ on the floor of the mouth of most vertebrates, in man other mammals is the principal organ of taste, aids in the prehension of food, in swallowing, and in modifying the voice as in speech.
43588	skin development	P	The process whose specific outcome is the progression of the skin over time, from its formation to the mature structure. The skin is the external membranous integument of an animal. In vertebrates the skin generally consists of two layers, an outer nonsensitive and nonvascular epidermis (cuticle or skarfskin) composed of cells which are constantly growing and multiplying in the deeper, and being thrown off in the superficial layers, as well as an inner vascular dermis (cutis, corium or true skin) composed mostly of connective tissue.
43589	skin morphogenesis	P	The process in which the anatomical structures of the skin are generated and organized. The skin is the external membranous integument of an animal. In vertebrates the skin generally consists of two layers, an outer nonsensitive and nonvascular epidermis (cuticle or skarfskin) composed of cells which are constantly growing and multiplying in the deeper, and being thrown off in the superficial layers, as well as an inner, sensitive and vascular dermis (cutis, corium or true skin) composed mostly of connective tissue.
43590	bacterial nucleoid	C	The region of a bacterial cell to which the DNA is confined.
43591	endospore external encapsulating structure	C	The structures that lie outside the inner membrane and surround the entire endospore; consists of a peptidoglycan-containing inner layer (the endospore cortex) surrounded by a multilayered proteinaceous coat. An exosporium may be present as an extreme outer layer.
43592	exosporium	C	The outermost layer of a bacterial endospore, which is loosely attached and located outside of the endospore coat. It is generally composed of protein, carbohydrate, and perhaps lipid.
43593	endospore coat	C	The layer in a bacterial endospore that lies under the exosporium, and is impermeable to many toxic molecules. The coat may also contain enzymes that are involved in endospore germination.
43594	outer endospore membrane	C	The outer membrane around a bacterial endospore, located between the endospore cortex and endospore coat.
43595	endospore cortex	C	A layer surrounding a bacterial endospore found inside the outer endospore membrane, but outside the membrane surrounding the endospore core. It consists of peptidoglycan of a different chemical nature than that found in vegetative cell walls which results in less cross-linking of peptidoglycan.
43596	nuclear replication fork	C	The Y-shaped region of a nuclear replicating DNA molecule, resulting from the separation of the DNA strands and in which the synthesis of new strands takes place. Also includes associated protein complexes.
43597	cytoplasmic replication fork	C	The Y-shaped region of a cytoplasmic replicating DNA molecule, resulting from the separation of the DNA strands and in which the synthesis of new strands takes place. Also includes associated protein complexes.
43598	cytoplasmic DNA replication factor C complex	C	A cytoplasmic complex of two polypeptides that loads the DNA polymerase processivity factor proliferating cell nuclear antigen (PCNA) onto DNA, thereby permitting processive DNA synthesis catalyzed by DNA polymerase. Examples of this component are found in prokaryotic species.
43599	nuclear DNA replication factor C complex	C	A nuclear complex of five polypeptides that loads the DNA polymerase processivity factor proliferating cell nuclear antigen (PCNA) onto DNA, thereby permitting processive DNA synthesis catalyzed by DNA polymerase delta or epsilon. In Saccharomyces and several other species, the subunits are known as Rfc1p-Rfc5p, although subunit names do not necessarily correspond between different species.
43600	cytoplasmic replisome	C	A multi-component enzymatic machine at the cytoplasmic replication fork, which mediates DNA replication. Includes DNA primase, DNA polymerase, DNA helicase, and other proteins.
43601	nuclear replisome	C	A multi-component enzymatic machine at the nuclear replication fork, which mediates DNA replication. Includes DNA primase, one or more DNA polymerases, DNA helicases, and other proteins.
43602	nitrate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of nitrates, inorganic or organic salts and esters of nitric acid.
43603	cellular amide metabolic process	P	The chemical reactions and pathways involving an amide, any derivative of an oxoacid in which an acidic hydroxy group has been replaced by an amino or substituted amino group, as carried out by individual cells.
43604	amide biosynthetic process	P	The chemical reactions and pathways resulting in the formation of an amide, any derivative of an oxoacid in which an acidic hydroxy group has been replaced by an amino or substituted amino group.
43605	cellular amide catabolic process	P	The chemical reactions and pathways resulting in the breakdown of an amide, any derivative of an oxoacid in which an acidic hydroxy group has been replaced by an amino or substituted amino group.
43606	formamide metabolic process	P	The chemical reactions and pathways involving formamide, the simplest amide, HCONH2, derived from formic acid.
43607	formamide biosynthetic process	P	The chemical reactions and pathways resulting in the formation of formamide, the simplest amide, HCONH2, derived from formic acid.
43608	formamide catabolic process	P	The chemical reactions and pathways resulting in the breakdown of formamide, the simplest amide, HCONH2, derived from formic acid.
43609	regulation of carbon utilization	P	Any process that modulates the frequency, rate, or extent of carbon utilization.
43610	regulation of carbohydrate utilization	P	Any process that modulates the frequency, rate or extent of carbohydrate utilization.
43611	isoprene metabolic process	P	The chemical reactions and pathways involving isoprene, C5H8.
43612	isoprene biosynthetic process	P	The chemical reactions and pathways resulting in the formation of isoprene, C5H8.
43613	isoprene catabolic process	P	The chemical reactions and pathways resulting in the breakdown of isoprene, C5H8.
43614	multi-eIF complex	C	A multifactor complex composed of multiple translation initiation factors and the initiatior tRNAiMet, which is ready to bind to the small (40S) ribosome to form the 43S preinitiation complex. In S. cerevisiae, this complex is composed of eIF1, eIF2, eIF3, and eIF5.
43615	astrocyte cell migration	P	The orderly movement of an astrocyte, a class of large neuroglial (macroglial) cells in the central nervous system, the largest and most numerous neuroglial cells in the brain and spinal cord.
43616	keratinocyte proliferation	P	The multiplication or reproduction of keratinocytes, resulting in the expansion of a cell population. Keratinocytes are epidermal cells which synthesize keratin and undergo a characteristic change as they move upward from the basal layers of the epidermis to the cornified (horny) layer of the skin.
43617	cellular response to sucrose starvation	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of sucrose.
43618	regulation of transcription from RNA polymerase II promoter in response to stress	P	Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).
43619	regulation of transcription from RNA polymerase II promoter in response to oxidative stress	P	Modulation of the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating the organism is under oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
43620	regulation of DNA-templated transcription in response to stress	P	Modulation of the frequency, rate or extent of transcription from a DNA template as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).
43621	protein self-association	F	Interacting selectively and non-covalently with a domain within the same polypeptide.
43622	cortical microtubule organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of structures formed of microtubules and associated proteins in the cell cortex, i.e. just beneath the plasma membrane of a cell.
43623	cellular protein complex assembly	P	The aggregation, arrangement and bonding together of a set of components to form a protein complex, occurring at the level of an individual cell.
43624	cellular protein complex disassembly	P	The disaggregation of a protein complex into its constituent components, occurring at the level of an individual cell. Protein complexes may have other associated non-protein prosthetic groups, such as nucleic acids, metal ions or carbohydrate groups.
43625	delta DNA polymerase complex	C	A multimeric DNA polymerase enzyme complex which differs in composition amongst species; in humans it is a heterotetramer of four subunits of approximately 125, 50, 68 and 12kDa, while in S. cerevisiae, it has three different subunits which form a heterotrimer, and the active enzyme is a dimer of this heterotrimer. Functions in DNA replication, mismatch repair and excision repair.
43626	PCNA complex	C	A protein complex composed of three identical PCNA monomers, each comprising two similar domains, which are joined in a head-to-tail arrangement to form a homotrimer. Forms a ring-like structure in solution, with a central hole sufficiently large to accommodate the double helix of DNA. Originally characterized as a DNA sliding clamp for replicative DNA polymerases and as an essential component of the replisome, and has also been shown to be involved in other processes including Okazaki fragment processing, DNA repair, translesion DNA synthesis, DNA methylation, chromatin remodeling and cell cycle regulation.
43627	response to estrogen	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stimulus by an estrogen, C18 steroid hormones that can stimulate the development of female sexual characteristics.
43628	ncRNA 3'-end processing	P	Any process involved in forming the mature 3' end of a non-coding RNA molecule.
43629	ncRNA polyadenylation	P	The enzymatic addition of a sequence of adenylyl residues at the 3' end of a non-coding RNA (ncRNA) molecule. In eukaryotes, substrates include nuclear non-coding RNAs such as precursors and a variety of incorrectly processed forms of snRNAs, snoRNAs, rRNAs, and tRNAs, as well as discarded RNA fragments which have been removed from ncRNA primary transcripts. Polyadenylation of precursors is often linked to termination of transcription, but polyadenylation of RNAs targeted for degradation may also occur post-transcriptionally. This polyadenylation is important both for 3'-end processing to produce mature ncRNA species and also for targeting incorrectly processed or discarded RNA molecules for degradation.
43630	ncRNA polyadenylation involved in polyadenylation-dependent ncRNA catabolic process	P	The enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end of a non-coding RNA, occurring as part of the process of polyadenylation-dependent non-coding RNA catabolism.
43631	RNA polyadenylation	P	The enzymatic addition of a sequence of adenylyl residues at the 3' end of an RNA molecule.
43632	modification-dependent macromolecule catabolic process	P	The chemical reactions and pathways resulting in the breakdown of a macromolecule, initiated by covalent modification of the target molecule.
43633	polyadenylation-dependent RNA catabolic process	P	The chemical reactions and pathways resulting in the breakdown of an RNA molecule, initiated by initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3'-end of the target RNA.
43634	polyadenylation-dependent ncRNA catabolic process	P	The chemical reactions and pathways resulting in the breakdown of a noncoding RNA (ncRNA) molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target ncRNA.
43635	methylnaphthalene catabolic process	P	The chemical reactions and pathways resulting in the breakdown of methylnaphthalene, an organic compound, C10H7CH3, obtained from coal tar.
43636	bisphenol A catabolic process	P	The chemical reactions and pathways resulting in the breakdown of bisphenol A, 4,4'-(propane-2,2-diyl)diphenol, a synthetic, aromatic organic compound used as a monomer in the manufacture of polycarbonate plastic and in the manufacture of epoxy resins.
43637	puromycin metabolic process	P	The chemical reactions and pathways involving puromycin, 3'-deoxy-N,N-dimethyl-3'-(O-methyl-L-tyrosinamido)adenosine, an aminonucleoside antibiotic that is a potent inhibitor of translation; produced by the bacterium Streptomyces alboniger.
43638	puromycin biosynthetic process	P	The chemical reactions and pathways resulting in the formation of puromycin, an aminonucleoside antibiotic that is a potent inhibitor of translation; produced by the bacterium Streptomyces alboniger.
43639	benzoate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of benzoate, the anion of benzoic acid (benzenecarboxylic acid), a fungistatic compound widely used as a food preservative; it is conjugated to glycine in the liver and excreted as hippuric acid.
43640	benzoate catabolic process via hydroxylation	P	The chemical reactions and pathways resulting in the breakdown of benzoate, by its hydroxylation to cis-1,2-dihydroxybenzoate followed by dehydrogenation to catechol.
43641	novobiocin metabolic process	P	The chemical reactions and pathways involving novobiocin, a coumarin antibiotic produced by the bacterium Gyrasestreptomyces spheroides, that acts by inhibiting DNA gyrase.
43642	novobiocin biosynthetic process	P	The chemical reactions and pathways resulting in the formation of novobiocin, a coumarin antibiotic produced by the bacterium Gyrasestreptomyces spheroides, that acts by inhibiting DNA gyrase.
43643	tetracycline metabolic process	P	The chemical reactions and pathways involving tetracycline, (4S,4aS,5aS,6S,12aS)-4-(dimethylamino)-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide, a broad-spectrum antibiotic produced by streptomyces bacteria that blocks binding of aminoacyl tRNA to the ribosomes of both Gram-positive and Gram-negative organisms (and those of organelles).
43644	tetracycline biosynthetic process	P	The chemical reactions and pathways resulting in the formation of tetracycline, (4S,4aS,5aS,6S,12aS)-4-(dimethylamino)-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide, a broad-spectrum antibiotic produced by streptomyces bacteria that blocks binding of aminoacyl tRNA to the ribosomes of both Gram-positive and Gram-negative organisms (and those of organelles).
43645	cephalosporin metabolic process	P	The chemical reactions and pathways involving a cephalosporin, any of large class of tetracyclic triterpene broad-spectrum antibiotics similar both chemically and in their mode of action to penicillin, first isolated from the culture filtrates of mediterranean fungus acremonium (cephalosporium acremonium), and effective against gram-positive bacteria.
43646	cephalosporin biosynthetic process	P	The chemical reactions and pathways resulting in the formation of a cephalosporin, any of large class of tetracyclic triterpene broad-spectrum antibiotics similar both chemically and in their mode of action to penicillin, first isolated from the culture filtrates of mediterranean fungus acremonium (cephalosporium acremonium), and effective against gram-positive bacteria.
43647	inositol phosphate metabolic process	P	The chemical reactions and pathways involving inositol phosphate, 1,2,3,4,5,6-cyclohexanehexol, with one or more phosphate groups attached.
43648	dicarboxylic acid metabolic process	P	The chemical reactions and pathways involving dicarboxylic acids, any organic acid containing two carboxyl (COOH) groups or anions (COO-).
43649	dicarboxylic acid catabolic process	P	The chemical reactions and pathways resulting in the breakdown of dicarboxylic acids, any organic acid containing two carboxyl (-COOH) groups.
43650	dicarboxylic acid biosynthetic process	P	The chemical reactions and pathways resulting in the formation of dicarboxylic acids, any organic acid containing two carboxyl (-COOH) groups.
43651	linoleic acid metabolic process	P	The chemical reactions and pathways involving linoleic acid, an unsaturated omega-6 fatty acid that has the molecular formula C18H32O2.
43652	engulfment of apoptotic cell	P	The removal of the apoptotic cell by phagocytosis, by a neighboring cell or by a phagocyte.
43653	mitochondrial fragmentation involved in apoptotic process	P	The change in the morphology of the mitochondria in an apoptotic cell from a highly branched network to a fragmented vesicular form.
43654	recognition of apoptotic cell	P	The process in which a cell interprets signals (in the form of specific proteins and lipids) on the surface of a dying cell which it will engulf and remove by phagocytosis.
43655	extracellular space of host	C	The space within a host but external to the plasma membrane of host cells, e.g. within host bloodstream.
43656	intracellular region of host	C	That space within the plasma membrane of a host cell.
43657	host cell	C	A cell within a host organism. Includes the host plasma membrane and any external encapsulating structures such as the host cell wall and cell envelope.
43658	host symbiosome	C	A double-enveloped cell compartment, composed of the endosymbiont with its plasmalemma (as inner envelope) and an outer envelope (the perisymbiontic membrane) derived from the host cell.
43659	symbiosome	C	A double-enveloped cell compartment, composed of an endosymbiont with its plasmalemma (as inner envelope) and a non-endosymbiotic outer envelope (the perisymbiontic membrane).
43660	bacteroid-containing symbiosome	C	A symbiosome containing any of various structurally modified bacteria, such as those occurring on the root nodules of leguminous plants.
43661	peribacteroid membrane	C	A membrane that surrounds one or more bacteroids (such as nitrogen-fixing bacteroids within legume root nodule cells).
43662	peribacteroid fluid	C	The soluble material inside the peribacteroid membrane, but outside of the bacteroid, within a bacteroid-containing symbiosome.
43663	host bacteroid-containing symbiosome	C	A symbiosome containing any of various structurally modified bacteria, such as those occurring on the root nodules of leguminous plants, of a host cell.
43664	host peribacteroid membrane	C	A host-derived membrane that surrounds one or more bacteroids (such as nitrogen-fixing bacteroids within legume root nodule cells).
43665	host peribacteroid fluid	C	The soluble material inside the peribacteroid membrane, but outside of the bacteroid, within a bacteroid-containing symbiosome of a host cell.
43666	regulation of phosphoprotein phosphatase activity	P	Any process that modulates the frequency, rate or extent of phosphoprotein phosphatase activity, the catalysis of the hydrolysis of phosphate from a phosphoprotein.
43667	pollen wall	C	The complex wall surrounding a pollen grain.
43668	exine	C	The outer layer of the pollen grain wall which is composed primarily of sporopollenin.
43669	ectexine	C	The outer part of the exine, which stains positively with basic fuchsin in optical microscopy and has higher electron density in conventionally prepared TEM sections.
43670	foot layer	C	The inner layer of the ectexine.
43671	endexine	C	The inner part of the exine, which stains.
43672	nexine	C	The inner, non-sculptured part of the exine which lies below the sexine.
43673	sexine	C	The outer, sculptured layer of the exine, which lies above the nexine.
43674	columella	C	A rod-like element of the sexine and ectexine, supporting either the tectum (the layer of sexine which forms a roof over the columella), or supporting a caput (an architectural element on top of a columella).
43675	sculpture element	C	The third layer of the sexine.
43676	tectum	C	The layer of sexine which forms a roof over the columella, granules or other infratectal elements.
43677	germination pore	C	A small pore in the outer wall of a mycelial spore through which the germ tube exits upon germination. It can be apical or eccentric in its location.
43678	intine	C	The innermost of the major layers of the pollen grain wall which underlies the exine and borders the cytoplasm.
43679	axon terminus	C	Terminal inflated portion of the axon, containing the specialized apparatus necessary to release neurotransmitters. The axon terminus is considered to be the whole region of thickening and the terminal button is a specialized region of it.
43680	filiform apparatus	C	A complex of cell wall invaginations in a synergid cell, similar to those in transfer cells.
43682	copper-transporting ATPase activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Cu2+ = ADP + phosphate + Cu2+, directly driving the transport of the copper ions across a membrane.
43683	type IV pilus biogenesis	P	A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a type IV pilus. A type IV pilus is composed of a pilus fiber and approximately ten proteins at its base; type IV pili play a role in cell motility, adherence to substrates, and aggregation.
43684	type IV secretion system complex	C	A complex of proteins related to those involved in bacterial DNA conjugative transfer, that permits the transfer of DNA or proteins into the extracellular milieu or directly into host cells. In general the type IV complex forms a multisubunit cell-envelope-spanning structure composed of a secretion channel and often a pilus or other surface filament or protein(s).
43685	conversion of glutamyl-tRNA to glutaminyl-tRNA	P	The modification process that results in the conversion of glutamate charged on a tRNA(Gln) to glutaminyl-tRNA.
43686	co-translational protein modification	P	The process of covalently altering one or more amino acids in a protein after translation has begun but before the protein has been released from the ribosome.
43687	post-translational protein modification	P	The process of covalently altering one or more amino acids in a protein after the protein has been completely translated and released from the ribosome.
43688	conversion of aspartyl-tRNA to asparaginyl-tRNA	P	The modification process that results in the conversion of aspartate charged on a tRNA(Asn) to asparaginyl-tRNA.
43689	cell-cell adhesion involved in flocculation	P	The attachment of one single cell organism to another via adhesion molecules, occurring as a part of flocculation.
43690	cell-cell adhesion involved in flocculation via cell wall protein-carbohydrate interaction	P	The attachment of one single cell organism to another during flocculation via the interaction a protein in the cell wall of one cell with a carbohydrate in the cell wall of another In Saccharomyces this process is mannose-sensitive.
43691	reverse cholesterol transport	P	The directed movement of peripheral cell cholesterol, cholest-5-en-3-beta-ol, towards the liver for catabolism.
43692	monoterpene metabolic process	P	The chemical reactions and pathways involving monoterpenes, terpenes with a C10 structure.
43693	monoterpene biosynthetic process	P	The chemical reactions and pathways resulting in the formation of monoterpenes, terpenes with a C10 structure.
43694	monoterpene catabolic process	P	The chemical reactions and pathways resulting in the breakdown of monoterpenes, terpenes with a C10 structure.
43695	detection of pheromone	P	The series of events in which a pheromone stimulus is received by a cell and converted into a molecular signal.
43696	dedifferentiation	P	The process in which a specialized structure (cell, tissue or organ) loses structural or functional features that characterize it in the mature organism, or some other relatively stable phase of the organism's life history. Under certain conditions, these structures can revert back to the features of their ancestors.
43697	cell dedifferentiation	P	The process in which a specialized cell loses the structural or functional features that characterize it in the mature organism, or some other relatively stable phase of the organism's life history. Under certain conditions, these cells can revert back to the features of the stem cells that were their ancestors.
43698	iridosome	C	A tissue-specific, membrane-bounded cytoplasmic organelle within which purines crystalize in reflective stacks. Iridosomes are synthesized in iridophore cells and are silver, gold or iridescent in appearance.
43699	leucosome	C	A tissue-specific, membrane-bounded cytoplasmic organelle within which uric acid and/or purines crystalize in reflective stacks. Leucosomes are synthesized in leucophore cells and have a whitish cast.
43700	pterinosome	C	A tissue-specific, membrane-bounded cytoplasmic organelle within which pteridine pigments are synthesized and stored. Pterinosomes are synthesized in xanthophores and erythrophore cells and are yellow, orange or red in appearance.
43701	cyanosome	C	A tissue-specific, membrane-bounded cytoplasmic organelle within which an unknown blue pigment is localized. Cyanosomes are synthesized in cyanophores and are blue in appearance.
43702	carotenoid vesicle	C	A tissue-specific cytoplasmic vesicle surrounded by a membrane half-leaflet within which carotenoid pigments are stored. Carotenoid vesicles are synthesized in xanthophores and erythrophore cells and are yellow, orange or red in appearance.
43703	photoreceptor cell fate determination	P	The process in which a cell becomes capable of differentiating autonomously into a photoreceptor cell regardless of its environment; upon determination, the cell fate cannot be reversed.
43704	photoreceptor cell fate specification	P	The process in which a cell becomes capable of differentiating autonomously into a photoreceptor cell in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed.
43705	cyanophycin metabolic process	P	The chemical reactions and pathways involving cyanophycin, a non-protein, non-ribosomally produced amino acid polymer composed of an aspartic acid backbone and arginine side groups.
43706	heterophilic cell adhesion involved in cytoadherence to microvasculature, mediated by parasite protein	P	The attachment of an erythrocyte to the microvasculature via a parasite cell adhesion molecule. This may be via attachment to host endothelial cell ECM or to endothelial cell adhesion molecules. An example of this occurs during infection with the malaria parasite.
43707	cell adhesion involved in single-species biofilm formation in or on host organism	P	The attachment of a cell to either a host cell or a microbial cell of the same species, or to an underlying host substrate, such as the extracellular matrix, via cell adhesion molecules, occurring during the formation of a biofilm in or on a host species.
43708	cell adhesion involved in biofilm formation	P	The attachment of a cell to a solid substrate, via cell adhesion molecules, contributing to the formation of a biofilm.
43709	cell adhesion involved in single-species biofilm formation	P	The attachment of a cell to a solid substrate, via cell adhesion molecules, during the formation of a biofilm composed of microorganisms of the same species.
43710	cell adhesion involved in multi-species biofilm formation	P	The attachment of a cell to a solid substrate, via cell adhesion molecules, contributing to the formation of a biofilm composed of microorganisms of different species.
43711	pilus organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a pilus, a short filamentous structure on a bacterial cell, flagella-like in structure and generally present in many copies.
43712	2-hydroxyisocaproate CoA-transferase activity	F	Catalysis of the reaction: (R)-2-hydroxyisocaproate + isocaproyl-CoA = (R)-2-hydroxyisocaproyl-CoA + isocaproate.
43713	(R)-2-hydroxyisocaproate dehydrogenase activity	F	Catalysis of the reaction: 2-oxoisocaproate + NADH + H+ = (R)-2-hydroxyisocaproate + NAD+.
43714	(R)-citramalate synthase activity	F	Catalysis of the reaction: pyruvate + acetyl-CoA + H2O = (R)-citramalate + CoA.
43715	2,3-diketo-5-methylthiopentyl-1-phosphate enolase activity	F	Catalysis of the reaction: 2,3-diketo-5-methylthiopentyl-1-phosphate = H+ + 2-hydroxy 3-keto-5-methylthiopentenyl-1-phosphate. 2,3-diketo-5-methylthiopentyl-1-phosphate is also known as DK-MTP-1-P, and 2-hydroxy 3-keto-5-methylthiopentenyl-1-phosphate as HK-MTPenyl-1-P.
43716	2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate phosphatase activity	F	Catalysis of the reaction: 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate + H2O = 1,2-dihydroxy-5-(methylthio)pent-1-en-3-one + phosphate. 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate is also known as HK-MTPenyl-P, and 1,2-dihydroxy-3-keto-5-methylthiopentene as DHK-MTPene.
43717	2-hydroxyglutaryl-CoA dehydratase activity	F	Catalysis of the reaction: (R)-2-hydroxyglutaryl-CoA = H2O + glutaconyl-CoA.
43718	2-hydroxymethylglutarate dehydrogenase activity	F	Catalysis of the reaction: 2-(hydroxymethyl)glutarate + NAD(+) = 2-formylglutarate + H(+) + NADH.
43719	2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase activity	F	Catalysis of the reaction: 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol + O2 + H+ = 2-octaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinol + H2O.
43720	3-keto-5-aminohexanoate cleavage activity	F	Catalysis of the reaction: 3-keto-5-aminohexanoate + acetyl-CoA = L-3-aminobutyryl-CoA + acetoacetate.
43721	4-hydroxybutanoyl-CoA dehydratase activity	F	Catalysis of the reaction: 4-hydroxybutanoyl-CoA = vinylacetyl-CoA + H2O.
43722	4-hydroxyphenylacetate decarboxylase activity	F	Catalysis of the reaction: (4-hydroxyphenyl)acetate + H(+) = 4-cresol + CO(2).
43723	2,5-diamino-6-ribitylamino-4(3H)-pyrimidinone 5'-phosphate deaminase activity	F	Catalysis of the reaction: 2,5-diamino-6-(5-phospho-D-ribitylamino)pyrimidin-4(3H)-one + H2O = 5-amino-6-(5-phospho-D-ribosylamino)uracil + ammonia.
43724	2-keto-3-deoxygalactonate aldolase activity	F	Catalysis of the reaction: 2-keto-3-deoxygalactonate = D-glyceraldehyde + pyruvate.
43725	2-keto-3-deoxygluconate aldolase activity	F	Catalysis of the reaction: 2-keto-3-deoxygluconate = D-glyceraldehyde + pyruvate.
43726	5-amino-6-(5-phosphoribitylamino)uracil phosphatase activity	F	Catalysis of the reaction: 5-amino-6-(5-phosphoribitylamino)-2,4(1H,3H)-pyrimidinedione + H2O = 5-amino-6-ribitylamino-2,4(1H,3H)-pyrimidinedione + orthophosphate.
43727	5-amino-4-imidazole carboxylate lyase activity	F	Catalysis of the reaction: 5-aminoimidazole + CO2 = 5-amino-4-imidazole carboxylate.
43728	2-keto-4-methylthiobutyrate aminotransferase activity	F	Catalysis of the reaction: 2-keto-4-methylthiobutyrate + L-glutamine = 2-oxoglutaramate + L-methionine.
43729	2-amino-5-formylamino-6-(5-phosphoribosylamino)pyrimidin-4(3H)-one formate-lyase activity	F	Catalysis of the reaction: 2-amino-5-formylamino-6-(5-phosphoribosylamino)pyrimidin-4(3H)-one + H2O = 2,5-diamino-6-(5-phosphoribosylamino)pyrimidin-4(3H)-one + formate.
43730	5-ureido-4-imidazole carboxylate hydrolase activity	F	Catalysis of the reaction: 5-ureido-4-imidazole carboxylate + H2O = 5-amino-4-imidazole carboxylate + NH3 + CO2.
43731	6-hydroxynicotinate 3-monooxygenase activity	F	Catalysis of the oxidative decarboxylation of 6-hydroxynicotinate to 2,5-dihydroxypyridine, dependent on O2, NADH +H+ and FAD.
43732	6-hydroxynicotinate dehydrogenase activity	F	Catalysis of the reaction: 6-hydroxynicotinate + H(2)O + O(2) = 2,6-dihydroxynicotinate + H(2)O(2).
43733	DNA-3-methylbase glycosylase activity	F	Catalysis of the reaction: DNA containing 3-methylbase + H2O = DNA with abasic site + 3-methylbase. This reaction is the hydrolysis of DNA by cleavage of the N-C1' glycosidic bond between the damaged DNA 3-methylpurine or 3-methylpyrimidine base and the deoxyribose sugar to remove the methylated base, leaving an apurinic or apyrimidinic site.
43734	DNA-N1-methyladenine dioxygenase activity	F	Catalysis of the oxidative demethylation of N1-methyladenine and N3-methylcytosine in DNA, with concomitant decarboxylation of 2-oxoglutarate and releases oxidized methyl group on N1-methyladenine and N3-methylcytosine as formaldehyde.
43737	deoxyribonuclease V activity	F	Catalysis of the endonucleolytic cleavage at apurinic or apyrimidinic sites to products with a 5'-phosphate.
43738	reduced coenzyme F420 dehydrogenase activity	F	Catalysis of the reaction: methanophenazine + reduced coenzyme F420 = dihydromethanophenazine + coenzyme F420.
43739	G/U mismatch-specific uracil-DNA glycosylase activity	F	Catalysis of the removal of uracil from a U*G mispair by the cleavage the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar. The reaction releases a free uracil and leaves an apyrimidinic (AP) site.
43740	GTP cyclohydrolase IIa activity	F	Catalysis of the reaction: GTP + 3 H(2)O = 2-amino-5-formylamino-6-(1-D-ribosylamino)pyrimidin-4(3H)-one 5'-phosphate + 3 H(+) + 2 phosphate.
43741	L-2-aminoadipate N-acetyltransferase activity	F	Catalysis of the reaction: L-2-aminoadipate + acetyl-CoA = N2-acetyl-L-aminoadipate + CoA.
43743	LPPG:FO 2-phospho-L-lactate transferase activity	F	Catalysis of the reaction: 7,8-didemethyl-8-hydroxy-5-deazariboflavin + lactyl-2-diphospho-5'-guanosine = coenzyme F420-0 + GMP.
43744	N2-acetyl-L-aminoadipate kinase activity	F	Catalysis of the reaction: ATP + N-acetyl-L-aminoadipate = ADP + N-acetyl-L-aminoadipate 5-phosphate.
43745	N2-acetyl-L-aminoadipate semialdehyde dehydrogenase activity	F	Catalysis of the reaction: N2-acetyl-L-aminoadipyl-delta-phosphate + NADPH + H+ = N2-acetyl-L-aminoadipate semialdehyde + NADP+ + orthophosphate.
43746	N2-acetyl-L-lysine aminotransferase activity	F	Catalysis of the reaction: N2-acetyl-L-aminoadipate semialdehyde + L-glutamate = 2-oxoglutarate + N2-acetyl-L-lysine.
43747	N2-acetyl-L-lysine deacetylase activity	F	Catalysis of the reaction: N2-acetyl-L-lysine + H2O = acetate + L-lysine.
43748	O-succinylbenzoate synthase activity	F	Catalysis of the reaction: 2-succinylbenzoate + H2O = 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate.
43749	phenol, water dikinase activity	F	Catalysis of the reaction: phenol + MgATP + H2O = phenylphosphate + MgAMP + orthophosphate.
43750	phosphatidylinositol alpha-mannosyltransferase activity	F	Catalysis of the transfer of one or more alpha-D-mannose residues from GDP-mannose to positions 2,6 and others in 1-phosphatidyl-myo-inositol.
43751	polyphosphate:AMP phosphotransferase activity	F	Catalysis of the reaction: (polyphosphate)n + AMP = (polyphosphate)n-1 + ADP.
43752	adenosylcobinamide kinase activity	F	Catalysis of the reaction: RTP + adenosylcobinamide = adenosylcobinamide phosphate + RDP (where RTP is either ATP or GTP).
43754	dihydrolipoyllysine-residue (2-methylpropanoyl)transferase activity	F	Catalysis of the reaction: 2-methylpropanoyl-CoA + enzyme N6-(dihydrolipoyl)lysine = CoA + enzyme N6-(S-[2-methylpropanoyl]dihydrolipoyl)lysine.
43755	alpha-ribazole phosphatase activity	F	Catalysis of the reaction: alpha-ribazole 5'-phosphate + H(2)O = alpha-ribazole + phosphate.
43756	adenosylcobinamide hydrolase activity	F	Catalysis of the reaction: adenosylcobinamide + H(2)O = (R)-1-aminopropan-2-ol + adenosylcobyrate.
43757	adenosylcobinamide-phosphate synthase activity	F	Catalysis of the reactions: ATP + adenosylcobyric acid + (R)-1-aminopropan-2-yl phosphate = ADP + phosphate + adenosylcobinamide phosphate, and ATP + adenosylcobyric acid + (R)-1-aminopropan-2-ol = ADP + phosphate + adenosylcobinamide.
43758	acetate-CoA ligase (ADP-forming) activity	F	Catalysis of the reaction: ATP + acetate + CoA = ADP + phosphate + acetyl-CoA.
43759	branched-chain acyl-CoA synthetase (ADP-forming) activity	F	Catalysis of the reaction: ATP + 2-methylbutanoate + CoA = ADP + orthophosphate + 2-methylbutanoyl-CoA.
43760	acetyldiaminopimelate aminotransferase activity	F	Catalysis of the reaction: N-acetyl-L-2,6-diaminoheptanedioate + 2-oxoglutarate = N-acetyl-2-L-amino-6-oxoheptanedioate + L-glutamate.
43761	archaetidylserine synthase activity	F	Catalysis of the reaction: CDP-digeranylgeranylglycerol + L-serine = archaetidylserine + CMP.
43762	aryl-CoA synthetase (ADP-forming) activity	F	Catalysis of the reaction: ATP + phenylacetate + CoA = ADP + orthophosphate + phenylacetyl-CoA.
43763	UTP:glucose-1-phosphate uridylyltransferase regulator activity	F	Modulates the activity of UTP:glucose-1-phosphate uridylyltransferase.
43764	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase activity	F	Catalysis of the reaction: UDP-3-O-(3-hydroxytetradecanoyl)glucosamine + (R)-3-hydroxytetradecanoyl-[acyl-carrier protein] = UDP-2,3-bis(3-hydroxytetradecanoyl)glucosamine + [acyl-carrier protein].
43765	T/G mismatch-specific endonuclease activity	F	Catalysis of the repair of T/G mismatches arising from deamination of 5-methylcytosine in DNA by nicking double-stranded DNA within the sequence CT(AT)GN or NT(AT)GG next to the mismatched thymidine residue. The incision is mismatch-dependent and strand-specific, in favor of the G-containing strand. The incision serves as a starting point for subsequent excision repair by DNA polymerase I, which excises thymidine and reinserts cytidine.
43766	Sep-tRNA:Cys-tRNA synthase activity	F	Catalysis of the reaction: O-phospho-L-seryl-tRNACys + sulfide = L-cysteinyl-tRNACys + phosphate.
43767	pyrrolysyl-tRNA synthetase activity	F	Catalysis of the reaction: ATP + L-pyrrolysine + tRNA(Pyl) = AMP + diphosphate + L-pyrrolysyl-tRNA(Pyl).
43768	S-ribosylhomocysteine lyase activity	F	Catalysis of the reaction: S-(5-deoxy-D-ribos-5-yl)-L-homocysteine = (S)-4,5-dihydroxypentane-2,3-dione + L-homocysteine.
43769	Tpg-containing telomere binding complex	C	A complex composed of four polypeptides, a telomere-protecting terminal protein (Tpg), a telomere-associated protein (Tap), DNA polymerase (PolA) and topoisomerase I (TopA), that functions in the replication of the telomeric regions of linear chromosomes, plasmids and circular replicons of some bacterial species.
43770	demethylmenaquinone methyltransferase activity	F	Catalysis of the reaction: 2-demethylmenaquinone + S-adenosyl-L-methionine = menaquinone + S-adenosyl-L-homocysteine.
43771	cytidine kinase activity	F	Catalysis of the reaction: ATP + cytidine = ADP + CMP.
43772	acyl-phosphate glycerol-3-phosphate acyltransferase activity	F	Catalysis of the reaction: acyl phosphate + sn-glycerol 3-phosphate = 1-acyl-sn-glycerol 3-phosphate + orthophosphate.
43773	coenzyme F420-0 gamma-glutamyl ligase activity	F	Catalysis of the reactions: (1) GTP + F420-0 + L-glutamate = GDP + phosphate + F420-1, and (2) GTP + F420-1 + L-glutamate = GDP + phosphate + gamma-F420-2. This is the GTP-dependent successive addition of two L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form F420-0-glutamyl-glutamate (F420-2), with a gamma-linkage between the two glutamates.
43774	coenzyme F420-2 alpha-glutamyl ligase activity	F	Catalysis of the reaction: coenzyme F420-2 + L-glutamate + GTP = coenzyme F420-3 + GDP + orthophosphate.
43775	cobyrinate a,c-diamide synthase activity	F	Catalysis of the reaction: cobyrinate + 2 L-glutamine + 2 ATP + 2 H2O = cob(II)yrinate a,c-diamide + 2 L-glutamate + 2 ADP + 2 orthophosphate.
43776	cobalt-precorrin-6B C5-methyltransferase activity	F	Catalysis of the reaction: S-adenosylmethionine + cobalt-precorrin 6B = S-adenosylhomocysteine + cobalt-precorrin 7.
43777	cobalt-precorrin-7 C15-methyltransferase activity	F	Catalysis of the reaction: cobalt-precorrin 7 + S-adenosyl-L-methionine = cobalt-precorrin 8 + S-adenosyl-L-homocysteine + CO2.
43778	cobalt-precorrin-8 methylmutase activity	F	Catalysis of the reaction: cobalt-precorrin 8 = cobyrinate.
43779	cobalt-precorrin-5A acetaldehyde-lyase activity	F	Catalysis of the reaction: cobalt-precorrin 5A + H2O = cobalt-precorrin 5B + acetaldehyde.
43780	cobalt-precorrin-5B C1-methyltransferase activity	F	Catalysis of the reaction: cobalt-precorrin 5B + S-adenosylmethionine = S-adenosylhomocysteine + cobalt-precorrin 6A.
43781	cobalt-factor II C20-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + cobalt-factor II = S-adenosyl-L-homocysteine + cobalt-factor III.
43782	cobalt-precorrin-3 C17-methyltransferase activity	F	Catalysis of the reaction: cobalt-precorrin 3 + S-adenosyl-L-methionine = cobalt-precorrin 4 + S-adenosyl-L-homocysteine.
43783	oxidoreductase activity, oxidizing metal ions with flavin as acceptor	F	Catalysis of an oxidation-reduction in which the oxidation state of metal ion is altered and flavin acts as an electron acceptor.
43784	cob(II)yrinic acid a,c-diamide reductase activity	F	Catalysis of the reaction: 2 cob(I)yrinate a,c diamide + FMN + 3 H(+) = 2 cob(II)yrinate a,c diamide + FMNH(2).
43785	cinnamoyl-CoA:phenyllactate CoA-transferase activity	F	Catalysis of the reaction: (R)-3-phenyllactate + [(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonatooxy)oxolan-2-yl]methyl {[(3R)-3-hydroxy-2,2-dimethyl-3-({2-[(2-{[(2E)-3-phenylprop-2-enoyl]sulfanyl}ethyl)carbamoyl]ethyl}carbamoyl)propyl phosphonato]oxy}phosphonate = (R)-3-phenyllactoyl-CoA + trans-cinnamate.
43786	cinnamate reductase activity	F	Catalysis of the reaction: 3-phenylpropanoate + NAD+ = (E)-cinnamate + NADH + H+.
43791	dimethylamine methyltransferase activity	F	Catalysis of the reaction: dimethylamine + a dimethylamine corrinoid protein = a methylated dimethylamine corrinoid protein + methylamine.
43792	enamidase activity	F	Catalysis of the reaction: 1,4,5,6-tetrahydro-6-oxonicotinate + 2 H(2)O = 2-formylglutarate + NH(4)(+).
43793	beta-ribofuranosylaminobenzene 5'-phosphate synthase activity	F	Catalysis of the reaction: 4-aminobenzoate + 5-phospho-alpha-D-ribose 1-diphosphate = 4-(beta-D-ribofuranosyl)aminobenzene 5'-phosphate + CO2 + diphosphate.
43794	formate dehydrogenase (coenzyme F420) activity	F	Catalysis of the reaction: formate + coenzyme F420 = CO2 + reduced coenzyme F420.
43795	glyceraldehyde oxidoreductase activity	F	Catalysis of the reaction: D-glyceraldehyde + H2O + acceptor = D-glycerate + reduced acceptor.
43796	glyceraldehyde dehydrogenase (NADP) activity	F	Catalysis of the reaction: D-glyceraldehyde + H2O + NADP+ = D-glycerate + NADPH + H+.
43797	glyceraldehyde-3-phosphate dehydrogenase (ferredoxin) activity	F	Catalysis of the reaction: D-glyceraldehyde-3-phosphate + H2O + 2 oxidized ferredoxin = 3-phospho-D-glycerate + 2 H+ + 2 reduced ferredoxin.
43798	glycerate 2-kinase activity	F	Catalysis of the reaction: D-glycerate + ATP = 2-phospho-D-glycerate + ADP.
43799	glycine oxidase activity	F	Catalysis of the reactions: (1) glycine + H2O + O2 = glyoxylate + NH3 + hydrogen peroxide; (2) D-alanine + H2O + O2 = pyruvate + NH3 + hydrogen peroxide; (3) sarcosine + H2O + O2 = glyoxylate + methylamine + hydrogen peroxide; (4) N-ethylglycine + H2O + O2 = glyoxylate + ethylamine + hydrogen peroxide.
43800	hexulose-6-phosphate isomerase activity	F	Catalysis of the reaction: D-arabino-3-hexulose 6-phosphate = D-fructose 6-phosphate.
43801	hexulose-6-phosphate synthase activity	F	Catalysis of the reaction: D-ribulose 5-phosphate + formaldehyde = D-arabino-3-hexulose 6-phosphate.
43802	hydrogenobyrinic acid a,c-diamide synthase (glutamine-hydrolysing) activity	F	Catalysis of the reaction: 2 L-glutamine + 2 ATP + 2 H(2)O + hydrogenobyrinate = 2 L-glutamate + 2 ADP + 4 H(+) + hydrogenobyrinate a,c-diamide + 2 phosphate.
43803	hydroxyneurosporene-O-methyltransferase activity	F	Catalysis of the reaction: demethylspheroidene + S-adenosyl-L-methionine = spheroidene + S-adenosyl-L-homocysteine.
43804	imidazolone hydrolase activity	F	Catalysis of the reaction: N-formiminoglycine = imidazolone + H2O.
43805	indolepyruvate ferredoxin oxidoreductase activity	F	Catalysis of the reaction: (indol-3-yl)pyruvate + CoA + oxidized ferredoxin = S-2-(indol-3-yl)acetyl-CoA + CO2 + reduced ferredoxin.
43806	keto acid formate lyase activity	F	Catalysis of the reaction: 2-oxobutanoate + CoA = propionyl-CoA + formate.
43807	3-methyl-2-oxobutanoate dehydrogenase (ferredoxin) activity	F	Catalysis of the reaction: 3-methyl-2-oxobutanoate + CoA + oxidized ferredoxin = S-(2-methylpropanoyl)-CoA + CO2 + reduced ferredoxin.
43808	lyso-ornithine lipid acyltransferase activity	F	Catalysis of the reaction: lyso-ornithine lipid + acyl-[acyl-carrier protein] = ornithine lipid + [acyl-carrier protein].
43810	ornithine-acyl [acyl carrier protein] N-acyltransferase activity	F	Catalysis of the reaction: (3R)-3-hydroxyacyl-[acyl-carrier protein] + L-ornithine = lyso-ornithine lipid + [acyl-carrier protein].
43811	phosphate:acyl-[acyl carrier protein] acyltransferase activity	F	Catalysis of the reaction: acyl-[acyl-carrier protein] + orthophosphate = acyl phosphate + [acyl-carrier protein].
43812	phosphatidylinositol-4-phosphate phosphatase activity	F	Catalysis of the reaction: phosphatidylinositol-4-phosphate + H2O = phosphatidylinositol + orthophosphate.
43813	phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity	F	Catalysis of the reaction: phosphatidylinositol-3,5-bisphosphate + H2O = phosphatidylinositol-3-phosphate + orthophosphate.
43814	phospholactate guanylyltransferase activity	F	Catalysis of the reaction: 2-phospho-(S)-lactate + GTP = lactyl-2-diphospho-5'-guanosine + diphosphate.
43815	phosphoribosylglycinamide formyltransferase 2 activity	F	Catalysis of the reaction: formate + ATP + 5'-phospho-ribosylglycinamide = 5'-phosphoribosyl-N-formylglycinamide + ADP + diphosphate.
43816	phosphoserine-tRNA(Cys) ligase activity	F	Catalysis of the reaction: tRNA(Cys) + O-phospho-L-serine + ATP = AMP + diphosphate + phosphoseryl-tRNA(Cys).
43817	phosphosulfolactate synthase activity	F	Catalysis of the reaction: (2R)-O-phospho-3-sulfolactate = phosphoenolpyruvate + sulfite.
43818	precorrin-3B synthase activity	F	Catalysis of the reaction: H(+) + NADH + O(2) + precorrin-3A = H(2)O + NAD(+) + precorrin-3B.
43819	precorrin-6A synthase (deacetylating) activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + H(2)O + precorrin-5 = S-adenosyl-L-homocysteine + acetate + 2 H(+) + precorrin-6X.
43820	propionyl-CoA dehydrogenase activity	F	Catalysis of the irreversible NADH-dependent formation of propionyl-CoA from acryloyl-CoA.
43821	propionyl-CoA:succinate CoA-transferase activity	F	Catalysis of the reaction: succinate + propionyl-CoA = succinyl-CoA + propionate.
43822	ribonuclease M5 activity	F	Catalysis of the endonucleolytic cleavage of RNA, removing 21 and 42 nucleotides, respectively, from the 5'- and 3'-termini of a 5S-rRNA precursor.
43823	spheroidene monooxygenase activity	F	Catalysis of the reaction: spheroidene + O2 = spheroidenone + H2O.
43824	succinylglutamate-semialdehyde dehydrogenase activity	F	Catalysis of the reaction: N-succinyl-L-glutamate 5-semialdehyde + H(2)O + NAD(+) = N-succinyl-L-glutamate + 2 H(+) + NADH.
43825	succinylornithine transaminase activity	F	Catalysis of the reaction: 2-oxoglutarate + N(2)-succinyl-L-ornithine = N-succinyl-L-glutamate 5-semialdehyde + L-glutamate.
43826	sulfur oxygenase reductase activity	F	Catalysis of the reaction: 5 sulfur + oxygen + 4 H2O = sulfite + thiosulfate + 2 hydrogen sulfide + 9 H+.
43827	tRNA (adenine-57, 58-N(1)-) methyltransferase activity	F	Catalysis of the methylation of adenine-57 and adenine-58 in the T-loop of tRNA.
43828	tRNA 2-selenouridine synthase activity	F	Catalysis of the reaction: 5-methylaminomethyl-2-thiouridine + selenophosphate = 5-methylaminomethyl-2-selenouridine + phosphate (at the wobble position in tRNA).
43829	tRNA-specific adenosine-37 deaminase activity	F	Catalysis of the reaction: adenosine-37 + H2O = inosine-37 + NH3, in a tRNA-Ala molecule.
43830	thiol-driven fumarate reductase activity	F	Catalysis of the reaction: fumarate + coenzyme M + coenzyme B = succinate + coenzyme M + coenzyme B + heterodisulfide.
43831	thiosulfate dehydrogenase (quinone) activity	F	Catalysis of the reaction: 6-decylubiquinone + 2 thiosulfate = 6-decylubiquinol + tetrathionate.
43833	methylamine-specific methylcobalamin:coenzyme M methyltransferase activity	F	Catalysis of the reaction: a methylated methylamine corrinoid protein + coenzyme M = a methylamine corrinoid protein + methyl-CoM. This reaction is the transfer of the methyl group from the methylated corrinoid cofactor of a methylamine corrinoid protein to coenzyme M.
43834	trimethylamine methyltransferase activity	F	Catalysis of the reaction: trimethylamine + a trimethylamine corrinoid protein = a methylated trimethylamine corrinoid protein + dimethylamine.
43836	xanthine hydrolase activity	F	Catalysis of the reaction: xanthine + H2O = 4-ureido-5-imidazole carboxylate.
43837	valine dehydrogenase (NAD) activity	F	Catalysis of the reaction: L-valine + H2O + NAD+ = 3-methyl-2-oxobutanoate + NH3 + NADH.
43838	phosphatidylethanolamine:Kdo2-lipid A phosphoethanolamine transferase activity	F	Catalysis of the reaction: Kdo2-lipid A + phosphatidylethanolamine = phosphoethanolamine-Kdo2-lipid A + diacylglycerol.
43839	lipid A phosphate methyltransferase activity	F	Catalysis of the transfer of a methyl group from S-adenosylmethionine (SAM) to the 1-phosphate group of lipid A.
43840	branched-chain amino acid:2-keto-4-methylthiobutyrate aminotransferase activity	F	Catalysis of the reaction: 2-keto-4-methylthiobutyrate + L-phenylalanine = phenylpyruvate + L-methionine.
43841	(S)-lactate 2-kinase activity	F	Catalysis of the reaction: (S)-lactate + GTP = 2-phospho-(S)-lactate + GDP.
43842	Kdo transferase activity	F	Catalysis of the reactions: (KDO)-lipid IVA + CMP-3-deoxy-D-manno-octulosonate = KDO2-lipid IVA + CMP, and lipid IVA + CMP-3-deoxy-D-manno-octulosonate = (KDO)-lipid IVA + CMP.
43843	ADP-specific glucokinase activity	F	Catalysis of the reaction: ADP + D-glucose = AMP + D-glucose 6-phosphate.
43844	ADP-specific phosphofructokinase activity	F	Catalysis of the reaction: ADP + D-fructose 6-phosphate = AMP + D-fructose 1,6-bisphosphate.
43845	DNA polymerase III, proofreading complex	C	A subcomplex of DNA polymerase III composed of the epsilon subunit which has proofreading activity, and the theta subunit which enhances the epsilon subunit's proofreading activity.
43846	DNA polymerase III, clamp loader complex	C	A heptamer that includes the tau and gamma products of the dnaX gene and the chi/psi subcomplex. Confers structural asymmetry that allows the polymerase to replicate both leading and lagging strands.
43847	DNA polymerase III, clamp loader chi/psi subcomplex	C	A dimer composed of the chi and psi subunits which is a subassembly of the DNA polymerase III clamp loader complex and serves as a bridge between the DnaX complex and the single-stranded DNA-binding protein (SSB).
43848	excinuclease cho activity	F	Catalysis of the incision of damaged DNA on the 3' side of a lesion, typically at the ninth phosphodiester bond 3' of the damage.
43849	Ras palmitoyltransferase activity	F	Catalysis of the reaction: palmitoyl-CoA + protein-cysteine = S-palmitoyl protein + CoA, specific for Ras proteins.
43850	RecFOR complex	C	A heterotrimeric complex composed of the subunits RecF, RecO and RecR. Mediates the loading of RecA protein specifically onto SSB-coated gapped DNA during DNA repair.
43851	methanol-specific methylcobalamin:coenzyme M methyltransferase activity	F	Catalysis of the reaction: a methylated methanol corrinoid protein + coenzyme M = a methanol corrinoid protein + methyl-CoM. This reaction is the transfer of the methyl group from the methylated corrinoid cofactor of a methylamine corrinoid protein to coenzyme M.
43852	monomethylamine methyltransferase activity	F	Catalysis of the reaction: monomethylamine + a monomethylamine corrinoid protein = a methylated monomethylamine corrinoid protein + NH3.
43853	methanol-CoM methyltransferase complex	C	A heterotrimeric protein complex composed of a methanol methyltransferase subunit, a corrinoid protein and a methanol-specific corrinoid:coenzyme M methyltransferase subunit. Catalyzes the transfer of a methyl group from methanol to coenzyme M as part of the pathway of methanogenesis from methanol.
43854	cyclic nucleotide-gated mechanosensitive ion channel activity	F	Enables the transmembrane transfer of an ion by a channel that opens in response to a mechanical stress and when a cyclic nucleotide has been bound by the channel complex or one of its constituent parts.
43855	cyclic nucleotide-gated ion channel activity	F	Enables the transmembrane transfer of an ion by a channel that opens when a cyclic nucleotide has been bound by the channel complex or one of its constituent parts.
43856	anti-sigma factor antagonist activity	F	The function of binding to an anti-sigma factor and stopping, preventing or reducing the rate of its activity.
43857	N-acetylornithine carbamoyltransferase activity	F	Catalysis of the reaction: N(2)-acetyl-L-ornithine + carbamoyl phosphate = N(2)-acetyl-L-citrulline + H(+) + phosphate.
43858	arginine:ornithine antiporter activity	F	Catalysis of the reaction: arginine(out) + ornithine(in) = arginine(in) + ornithine(out).
43860	cyanophycin synthetase activity	F	Catalysis of the ATP-dependent polymerization of arginine and aspartate to multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer).
43861	agmatine:putrescine antiporter activity	F	Catalysis of the reaction: agmatine(out) + putrescine(in) = agmatine(in) + putrescine(out).
43862	arginine:agmatine antiporter activity	F	Catalysis of the reaction: arginine(out) + agmatine(in) = arginine(in) + agmatine(out).
43863	4-hydroxy-2-ketopimelate aldolase activity	F	Catalysis of the reaction: 4-hydroxy-2-ketopimelate = succinate semialdehyde + pyruvate.
43864	indoleacetamide hydrolase activity	F	Catalysis of the reaction: indole-3-acetamide + H2O = indole-3-acetate + NH3. Indole-3-acetamide is known as IAM and indole-3-acetate as IAA.
43865	methionine transmembrane transporter activity	F	Enables the transfer of methionine from one side of a membrane to the other.
43866	adenylyl-sulfate reductase (thioredoxin) activity	F	Catalysis of the reaction: AMP + sulfite + thioredoxin disulfide = 5'-adenylyl sulfate + thioredoxin.
43867	7-cyano-7-deazaguanine tRNA-ribosyltransferase activity	F	Catalysis of the reaction: tRNA guanine + 7-cyano-7-deazaguanine = tRNA 7-cyano-7-deazaguanine + guanine.
43869	alpha-aminoadipate acetyltransferase activity	F	Catalysis of the reaction: alpha-aminoadipate + acetyl-CoA = N2-acetyl-alpha-aminoadipate + coenzyme A.
43870	N-acetyl-gamma-aminoadipyl-phosphate reductase activity	F	Catalysis of the reaction: N(2)-acetyl-L-aminoadipate-semialdehyde + NADP+ + phosphate = N(2)-acetyl-L-gamma-aminoadipyl phosphate + NADPH.
43871	delta1-piperideine-6-carboxylate dehydrogenase activity	F	Catalysis of the reaction: delta1-piperideine-6-carboxylate + NAD+ + 2 H2O = 2-aminoadipate + NADH + H+. Delta1-piperideine-6-carboxylate is also known as 2,3,4,5-tetrahydropyridine-2-carboxylate.
43872	lysine:cadaverine antiporter activity	F	Catalysis of the reaction: lysine(out) + cadaverine(in) = lysine(in) + cadaverine(out).
43873	pyruvate-flavodoxin oxidoreductase activity	F	Catalysis of the reaction: pyruvate + CoA + oxidized flavodoxin = acetyl-CoA + CO2 + reduced flavodoxin.
43874	acireductone synthase activity	F	Catalysis of the reactions: 5-(methylthio)-2,3-dioxopentyl phosphate + H2O = 1,2-dihydroxy-5-(methylthio)pent-1-en-3-one + phosphate; (1a) 5-(methylthio)-2,3-dioxopentyl phosphate = 2-hydroxy-5-(methylthio)-3-oxopent-1-enyl phosphate; (1b) 2-hydroxy-5-(methylthio)-3-oxopent-1-enyl phosphate + H2O = 1,2-dihydroxy-5-(methylthio)pent-1-en-3-one + phosphate.
43875	2-ketobutyrate formate-lyase activity	F	Catalysis of the reaction: 2-oxobutanoate + coenzyme A = propionyl-CoA + formate.
43876	D-threonine aldolase activity	F	Catalysis of the reaction: D-threonine (or D-allo-threonine) = glycine + acetaldehyde.
43877	galactosamine-6-phosphate isomerase activity	F	Catalysis of the reaction: D-galactosamine 6-phosphate + H2O = D-tagatose 6-phosphate + NH3.
43878	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity	F	Catalysis of the reaction: D-glyceraldehyde 3-phosphate + NAD+ + H2O = 3-phospho-D-glycerate + NADH + H+.
43879	glycolate transmembrane transporter activity	F	Enables the transfer of glycolate from one side of a membrane to the other. Glycolate is the smallest alpha-hydroxy acid (AHA).
43880	crotonyl-CoA reductase activity	F	Catalysis of the reduction of crotonyl-CoA to butyryl-CoA.
43881	mesaconyl-CoA hydratase activity	F	Catalysis of the hydration of mesaconyl-CoA to beta-methylmalyl-CoA.
43882	malate:sodium symporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: malate(out) + Na+(out) = malate(in) + Na+(in).
43883	malolactic enzyme activity	F	Catalysis of the reaction: malate + H+ = L-lactate + CO2.
43884	CO-methylating acetyl-CoA synthase activity	F	Catalysis of the reaction: acetyl-CoA + corrinoid protein = CO + methylcorrinoid protein + CoA.
43885	carbon-monoxide dehydrogenase (ferredoxin) activity	F	Catalysis of the reaction: CO + H2O + oxidized ferredoxin = CO2 + reduced ferredoxin.
43886	structural constituent of carboxysome	F	The action of a molecule that contributes to the structural integrity of a carboxysome, an organelle found in the Cyanobacteria consisting of a proteinaceous coat and enzymes for the fixation of carbon dioxide.
43887	melibiose:sodium symporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: melibiose(out) + Na+(out) = melibiose(in) + Na+(in).
43888	(S)-2,3-di-O-geranylgeranylglyceryl phosphate synthase activity	F	Catalysis of the transfer of a geranylgeranyl group from geranylgeranyl diphosphate to (S)-3-O-geranylgeranylglyceryl phosphate to form (S)-2,3-di-O-geranylgeranylglyceryl phosphate.
43889	(S)-3-O-geranylgeranylglyceryl phosphate synthase activity	F	Catalysis of the alkylation of the primary hydroxyl group in (S)-glyceryl phosphate by geranylgeranyl diphosphate to form (S)-3-O-geranylgeranylglyceryl phosphate.
43890	N-acetylgalactosamine-6-sulfatase activity	F	Catalysis of the hydrolysis of the 6-sulfate groups of the N-acetyl-D-galactosamine 6-sulfate units of chondroitin sulfate and of the D-galactose 6-sulfate units of keratan sulfate.
43891	glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity	F	Catalysis of the reaction: D-glyceraldehyde 3-phosphate + phosphate + NAD(P)+ = 3-phospho-D-glyceroyl phosphate + NAD(P)H + H+.
43892	methylglyoxal reductase (NADPH-dependent) activity	F	Catalysis of the reaction: lactaldehyde + NADP+ = methylglyoxal + NADPH + H+.
43893	acetate:cation symporter activity	F	Catalysis of the transfer of acetate from one side of a membrane to the other according to the reaction: acetate(out) + cation(out) = acetate(in) + cation(in).
43894	acetyl-CoA synthetase acetyltransferase activity	F	Catalysis of the acetylation of residue Lys609 of the enzyme acetyl-CoA synthetase, using acetyl-CoA as substrate.
43895	cyclomaltodextrin glucanotransferase activity	F	Catalysis of the cyclization of part of a 1,4-alpha-D-glucan chain by formation of a 1,4-alpha-D-glucosidic bond.
43896	glucan 1,6-alpha-glucosidase activity	F	Catalysis of the hydrolysis of (1->6)-alpha-D-glucosidic linkages in (1->6)-alpha-D-glucans and derived oligosaccharides.
43897	glucan 1,4-alpha-maltohydrolase activity	F	Catalysis of the hydrolysis of (1->4)-alpha-D-glucosidic linkages in polysaccharides so as to remove successive alpha-maltose residues from the non-reducing ends of the chains.
43898	2,3-dihydroxybiphenyl 1,2-dioxygenase activity	F	Catalysis of the reaction: 2,3-dihydroxybiphenyl + O2 = 2-hydroxy-6-phenylhexa-2,4-dienoic acid.
43899	phosphoserine:homoserine phosphotransferase activity	F	Catalysis of the transfer of a phosphoryl group from phosphoserine to homoserine to form phosphohomoserine.
43900	regulation of multi-organism process	P	Any process that modulates the frequency, rate or extent of a multi-organism process, a process in which an organism has an effect on another organism of the same or different species.
43901	negative regulation of multi-organism process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of a multi-organism process, a process in which an organism has an effect on another organism of the same or different species.
43902	positive regulation of multi-organism process	P	Any process that activates or increases the frequency, rate or extent of a multi-organism process, a process in which an organism has an effect on another organism of the same or different species.
43903	regulation of symbiosis, encompassing mutualism through parasitism	P	Any process that modulates the frequency, rate or extent of symbiosis, an interaction between two organisms living together in more or less intimate association.
43904	isochorismate pyruvate lyase activity	F	Catalysis of the reaction: isochorismate = salicylate + pyruvate.
43905	Ser-tRNA(Thr) hydrolase activity	F	Catalysis of the hydrolysis of misacylated Ser-tRNA(Thr).
43906	Ala-tRNA(Pro) hydrolase activity	F	Catalysis of the hydrolysis of misacylated Ala-tRNA(Pro).
43907	Cys-tRNA(Pro) hydrolase activity	F	Catalysis of the hydrolysis of misacylated Cys-tRNA(Pro).
43908	Ser(Gly)-tRNA(Ala) hydrolase activity	F	Catalysis of the hydrolysis of misacylated Ser-tRNA(Ala) and Gly-tRNA(Ala).
43909	N-acetylcitrulline deacetylase activity	F	Catalysis of the reaction: N-acetyl-L-citrulline + H2O = citrulline + acetate.
43910	ATP:coenzyme F420 adenylyltransferase activity	F	Catalysis of the reaction: ATP + factor gamma-F420-2 + H+ = coenzyme F390-A + diphosphate.
43911	D-lysine transaminase activity	F	Catalysis of the reaction: D-lysine + 2-oxoglutarate = L-glutamate + 6-amino-2-oxohexanoate.
43912	D-lysine oxidase activity	F	Catalysis of the reaction: D-lysine + O2 + H2O = 6-amino-2-oxohexanoate + NH3 + hydrogen peroxide.
43913	chromosome segregation-directing complex	C	A trimeric protein complex which in E. coli is composed of the subunits MreB, MreC and MreD. The complex directs longitudinal cell wall synthesis, maintaining cell morphology.
43914	NADPH:sulfur oxidoreductase activity	F	Catalysis of the reaction: NADPH + H+ + sulfur = hydrogen sulfide + NADP+.
43915	L-seryl-tRNA(Sec) kinase activity	F	Catalysis of the reaction: ATP + L-seryl-tRNA(Sec) = ADP + O-phospho-L-seryl-tRNA(Sec).
43916	DNA-7-methylguanine glycosylase activity	F	Catalysis of the reaction: DNA containing 7-methylguanine + H2O = DNA with abasic site + 7-methylguanine. This reaction is the hydrolysis of DNA by cleavage of the N-C1' glycosidic bond between the damaged DNA 7-methylguanine and the deoxyribose sugar to remove the 7-methylguanine, leaving an abasic site.
43917	ribose 1,5-bisphosphate isomerase activity	F	Catalysis of the reaction: D-ribose 1,5-bisphosphate = D-ribulose 1,5-bisphosphate.
43918	cadaverine aminopropyltransferase activity	F	Catalysis of the reaction: S-adenosylmethioninamine + cadaverine = 5'-methylthioadenosine + N-(3-aminopropyl)cadaverine.
43919	agmatine aminopropyltransferase activity	F	Catalysis of the reaction: agmatine + S-adenosylmethioninamine = N1-aminopropylagmatine + 5'-methylthioadenosine.
43920	aminopropylagmatine ureohydrolase activity	F	Catalysis of the reaction: N1-aminopropylagmatine + H2O = spermidine + urea.
43921	modulation by host of viral transcription	P	Any process in which a host organism modulates the frequency, rate or extent of viral transcription.
43922	negative regulation by host of viral transcription	P	Any process in which a host organism stops, prevents, or reduces the frequency, rate or extent of viral transcription.
43923	positive regulation by host of viral transcription	P	Any process in which a host organism activates or increases the frequency, rate or extent of viral transcription, the synthesis of either RNA on a template of DNA or DNA on a template of RNA.
43924	suramin binding	F	Interacting selectively and non-covalently with suramin, a naphthalenesulfonic acid compound which is used in the treatment of diseases caused by trypanosomes and worms.
43927	exonucleolytic nuclear-transcribed mRNA catabolic process involved in endonucleolytic cleavage-dependent decay	P	The chemical reactions and pathways resulting in the breakdown of the transcript body of a nuclear-transcribed mRNA that occurs when the ends are not protected by the 5'-cap.
43928	exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay	P	The chemical reactions and pathways resulting in the breakdown of the transcript body of a nuclear-transcribed mRNA that occurs when the ends are not protected by the 3'-poly(A) tail.
43929	primary ovarian follicle growth involved in double layer follicle stage	P	Increase in size of primary follicles including oocyte growth and granulosa and/or theca cell proliferation until more than one layer of granulosa cells is present (preantral follicle), as part of the double layer follicle stage of oogenesis.
43930	primary ovarian follicle growth involved in primary follicle stage	P	Increase in size of primary follicles including oocyte growth and granulosa and/or theca cell proliferation until more than one layer of granulosa cells is present (preantral follicle) as part of the primary follicle stage of oogenesis.
43931	ossification involved in bone maturation	P	The formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone, involved in the progression of the skeleton from its formation to its mature state.
43932	ossification involved in bone remodeling	P	The formation or growth of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone, involved in response to injury or other physical, physiological or environmental stress stimuli.
43933	macromolecular complex subunit organization	P	Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a macromolecular complex.
43934	sporulation	P	The process whose specific outcome is the progression of a spore over time, from its initiation to the mature structure. A spore is a structure that can be used for dissemination, for survival of adverse conditions because of its heat and dessication resistance, and/or for reproduction.
43935	sexual sporulation resulting in formation of a cellular spore	P	The formation of spores derived from the products of meiosis. A cellular spore is a cell form that can be used for dissemination, for survival of adverse conditions because of its heat and dessication resistance, and/or for reproduction.
43936	asexual sporulation resulting in formation of a cellular spore	P	The formation of a cellular spore derived from the products of mitosis. A cellular spore is a cell form that can be used for dissemination, for survival of adverse conditions because of its heat and dessication resistance, and/or for reproduction.
43937	regulation of sporulation	P	Any process that modulates the frequency, rate or extent of sporulation, the process whose specific outcome is the progression of a spore over time, from its initiation to the mature structure.
43938	positive regulation of sporulation	P	Any process that activates, maintains or increases the frequency, rate or extent of sporulation, the process whose specific outcome is the progression of a spore over time, from its initiation to the mature structure.
43939	negative regulation of sporulation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of sporulation, the process whose specific outcome is the progression of a spore over time, from its initiation to the mature structure.
43940	regulation of sexual sporulation resulting in formation of a cellular spore	P	Any process that modulates the frequency, rate or extent of the formation of cellular spores derived from the products of meiosis.
43941	positive regulation of sexual sporulation resulting in formation of a cellular spore	P	Any process that activates, maintains or increases the frequency, rate or extent of the formation of cellular spores derived from the products of meiosis.
43942	negative regulation of sexual sporulation resulting in formation of a cellular spore	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the formation of cellular spores derived from the products of meiosis.
43943	regulation of asexual sporulation resulting in formation of a cellular spore	P	Any process that modulates the frequency, rate or extent of the formation of a cellular spore derived from the products of mitosis.
43944	negative regulation of asexual sporulation resulting in formation of a cellular spore	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the formation of a cellular spore derived from the products of mitosis.
43945	positive regulation of asexual sporulation resulting in formation of a cellular spore	P	Any process that activates, maintains or increases the frequency, rate or extent of the formation of a cellular spore derived from the products of mitosis.
43946	positive regulation of catalytic activity in other organism involved in symbiotic interaction	P	Any process in which an organism activates, maintains or increases the frequency, rate or extent of enzyme activity in a second organism, where the two organisms are in a symbiotic interaction.
43947	positive regulation by host of symbiont catalytic activity	P	Any process in which an organism activates, maintains or increases the frequency, rate or extent of symbiont enzyme activity. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.
43948	positive regulation by symbiont of host catalytic activity	P	Any process in which the symbiont activates, maintains or increases the frequency, rate or extent of host enzyme activity. The host is defined as the larger of the organisms involved in a symbiotic interaction.
43949	regulation of cAMP-mediated signaling	P	Any process which modulates the frequency, rate or extent of cAMP-mediated signaling, a series of molecular signals in which a cell uses cyclic AMP to convert an extracellular signal into a response.
43950	positive regulation of cAMP-mediated signaling	P	Any process which activates, maintains or increases the frequency, rate or extent of cAMP-mediated signaling, a series of molecular signals in which a cell uses cyclic AMP to convert an extracellular signal into a response.
43951	negative regulation of cAMP-mediated signaling	P	Any process which stops, prevents, or reduces the frequency, rate or extent of cAMP-mediated signaling, a series of molecular signals in which a cell uses cyclic AMP to convert an extracellular signal into a response.
43952	protein transport by the Sec complex	P	The process in which unfolded proteins are transported across the cytoplasmic membrane in Gram-positive and Gram-negative bacteria by the Sec complex, in a process involving proteolytic cleavage of an N-terminal signal peptide.
43953	protein transport by the Tat complex	P	The process in which folded proteins are transported across cytoplasmic membranes of bacteria and membranes of organelles derived from bacteria (chloroplasts and mitochondria) by the TAT complex.
43954	cellular component maintenance	P	The organization process that preserves a cellular component in a stable functional or structural state.
43955	3-hydroxypropionyl-CoA synthetase activity	F	Catalysis of the reaction: 3-hydroxypropionate + ATP + CoA = 3-hydroxypropionyl-CoA + AMP + diphosphate.
43956	3-hydroxypropionyl-CoA dehydratase activity	F	Catalysis of the reaction: 3-hydroxypropionyl-CoA = acrylyl-CoA + H2O.
43957	acryloyl-CoA reductase (NADP+) activity	F	Catalysis of the reaction: acryloyl-CoA + NADPH + H+ = propionyl-CoA + NADP+.
43958	acryloyl-CoA reductase activity	F	Catalysis of the reaction: acryloyl-CoA + NADH + H+ + a reduced electron-transfer flavoprotein = propionyl-CoA + NAD+ + an oxidized electron-transfer flavoprotein.
43959	L-erythro-3-methylmalyl-CoA lyase activity	F	Catalysis of the reaction: propionyl-CoA + glyoxylate = L-erythro-3-methylmalyl-CoA.
43960	L-erythro-3-methylmalyl-CoA dehydratase activity	F	Catalysis of the reaction: L-erythro-3-methylmalyl-CoA = mesaconyl-CoA + H2O.
43961	succinyl-CoA:(R)-citramalate CoA-transferase activity	F	Catalysis of the reaction: succinyl-CoA + (R)-citramalate = succinate + (R)-citramalyl-CoA.
43962	negative regulation by host of symbiont adenylate cyclase-mediated signal transduction	P	Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of adenylate cyclase-mediated signal transduction in the symbiont organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
43963	modulation by symbiont of host adenylate cyclase-mediated signal transduction	P	Any process in which the symbiont modulates the frequency, rate or extent of adenylate cyclase-mediated signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
43964	positive regulation by symbiont of host adenylate cyclase-mediated signal transduction	P	Any process in which an organism activates, maintains or increases the frequency, rate or extent of adenylate cyclase-mediated signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
43965	negative regulation by symbiont of host adenylate cyclase-mediated signal transduction	P	Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of adenylate cyclase-mediated signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
43966	histone H3 acetylation	P	The modification of histone H3 by the addition of an acetyl group.
43967	histone H4 acetylation	P	The modification of histone H4 by the addition of an acetyl group.
43968	histone H2A acetylation	P	The modification of histone H2A by the addition of an acetyl group.
43969	histone H2B acetylation	P	The modification of histone H2B by the addition of an acetyl group.
43970	histone H3-K9 acetylation	P	The modification of histone H3 by the addition of an acetyl group to a lysine residue at position 9 of the histone.
43971	histone H3-K18 acetylation	P	The modification of histone H3 by the addition of an acetyl group to a lysine residue at position 18 of the histone.
43972	histone H3-K23 acetylation	P	The modification of histone H3 by the addition of an acetyl group to a lysine residue at position 23 of the histone.
43973	histone H3-K4 acetylation	P	The modification of histone H3 by the addition of an acetyl group to a lysine residue at position 4 of the histone.
43974	histone H3-K27 acetylation	P	The modification of histone H3 by the addition of an acetyl group to a lysine residue at position 27 of the histone.
43975	histone H3-K36 acetylation	P	The modification of histone H3 by the addition of an acetyl group to a lysine residue at position 36 of the histone.
43976	histone H3-K79 acetylation	P	The modification of histone H3 by the addition of an acetyl group to a lysine residue at position 79 of the histone.
43977	histone H2A-K5 acetylation	P	The modification of histone H2A by the addition of an acetyl group to a lysine residue at position 5 of the histone.
43978	histone H2A-K9 acetylation	P	The modification of histone H2A by the addition of an acetyl group to a lysine residue at position 9 of the histone.
43979	histone H2B-K5 acetylation	P	The modification of histone H2B by the addition of an acetyl group to a lysine residue at position 5 of the histone.
43980	histone H2B-K12 acetylation	P	The modification of histone H2B by the addition of an acetyl group to a lysine residue at position 12 of the histone.
43981	histone H4-K5 acetylation	P	The modification of histone H4 by the addition of an acetyl group to a lysine residue at position 5 of the histone.
43982	histone H4-K8 acetylation	P	The modification of histone H4 by the addition of an acetyl group to a lysine residue at position 8 of the histone.
43983	histone H4-K12 acetylation	P	The modification of histone H4 by the addition of an acetyl group to a lysine residue at position 12 of the histone.
43984	histone H4-K16 acetylation	P	The modification of histone H4 by the addition of an acetyl group to a lysine residue at position 16 of the histone.
43985	histone H4-R3 methylation	P	The modification of histone H4 by addition of a methyl group to arginine at position 3 of the histone.
43987	histone H3-S10 phosphorylation	P	The modification of histone H3 by the addition of an phosphate group to a serine residue at position 10 of the histone.
43988	histone H3-S28 phosphorylation	P	The modification of histone H3 by the addition of an phosphate group to a serine residue at position 28 of the histone.
43989	histone H4-S1 phosphorylation	P	The modification of histone H4 by the addition of an phosphate group to a serine residue at position 1 of the histone.
43990	histone H2A-S1 phosphorylation	P	The modification of histone H2A by the addition of an phosphate group to a serine residue at position 1 of the histone.
43991	histone H2B-S14 phosphorylation	P	The modification of histone H2B by the addition of an phosphate group to a serine residue at position 14 of the histone.
43992	histone acetyltransferase activity (H3-K9 specific)	F	Catalysis of the reaction: acetyl-CoA + histone H3 L-lysine (position 9) = CoA + histone H3 N6-acetyl-L-lysine (position 9).
43993	histone acetyltransferase activity (H3-K18 specific)	F	Catalysis of the reaction: acetyl-CoA + histone H3 L-lysine (position 18) = CoA + histone H3 N6-acetyl-L-lysine (position 18).
43994	histone acetyltransferase activity (H3-K23 specific)	F	Catalysis of the reaction: acetyl-CoA + histone H3 L-lysine (position 23) = CoA + histone H3 N6-acetyl-L-lysine (position 23).
43995	histone acetyltransferase activity (H4-K5 specific)	F	Catalysis of the reaction: acetyl-CoA + histone H4 L-lysine (position 5) = CoA + histone H4 N6-acetyl-L-lysine (position 5).
43996	histone acetyltransferase activity (H4-K8 specific)	F	Catalysis of the reaction: acetyl-CoA + histone H4 L-lysine (position 8) = CoA + histone H4 N6-acetyl-L-lysine (position 8).
43997	histone acetyltransferase activity (H4-K12 specific)	F	Catalysis of the reaction: acetyl-CoA + histone H4 L-lysine (position 12) = CoA + histone H4 N6-acetyl-L-lysine (position 12).
43998	H2A histone acetyltransferase activity	F	Catalysis of the reaction: acetyl-CoA + histone H2A L-lysine = CoA + histone H2A N6-acetyl-L-lysine.
43999	histone acetyltransferase activity (H2A-K5 specific)	F	Catalysis of the reaction: acetyl-CoA + histone H2A L-lysine (position 5) = CoA + histone H2A N6-acetyl-L-lysine (position 5).
44000	movement in host	P	The process in which an organism or its progeny spreads from one location to another within its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
44001	migration in host	P	The directional movement of an organism from one place to another within its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
44002	acquisition of nutrients from host	P	The process that begins with the production and formation of structures and molecules in an organism that are required for the acquisition and utilization of nutrients from its host organism, and the ends with the acquirement of the nutrients. The host is defined as the larger of the organisms involved in a symbiotic interaction.
44003	modification by symbiont of host morphology or physiology	P	The process in which a symbiont organism effects a change in the structure or processes of its host organism.
44004	disruption by symbiont of host cell	P	Any process in which an organism has a negative effect on the functioning of the host's cells. The host is defined as the larger of the organisms involved in a symbiotic interaction.
44005	induction by symbiont in host of tumor, nodule, or growth	P	The process in which an organism causes the formation of a mass of cells in its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
44006	induction by symbiont in host of tumor, nodule, or growth containing transformed cells	P	The process in which an organism causes the formation in its host organism of a growth whose cells have been transformed and continue to exist in the absence of the first organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
44007	dissemination or transmission of symbiont from host	P	The movement of an organism from a host to another host or from a host to another place in the environment. The host is defined as the larger of the organisms involved in a symbiotic interaction.
44008	dissemination or transmission of symbiont from host by vector	P	The movement of an organism from one host to another (or another place in the environment) by means of a third organism (often an insect or other animal). The host is defined as the larger of the organisms involved in a symbiotic interaction.
44009	viral transmission by vector	P	The transfer of virions by means of an organism (often an insect or other animal) in order to create new infection.
44010	single-species biofilm formation	P	A process in which planktonically growing microorganisms of the same species grow at a liquid-air interface or on a solid substrate under the flow of a liquid and produce extracellular polymers that facilitate matrix formation, resulting in a change in the organisms' growth rate and gene transcription.
44011	single-species biofilm formation on inanimate substrate	P	A process in which microorganisms of the same species attach to and grow on an inanimate surface such as a rock or pipe, and produce extracellular polymers that facilitate attachment and matrix formation, resulting in an alteration in the phenotype of the organisms with respect to growth rate and gene transcription.
44012	histone acetyltransferase activity (H2A-K9 specific)	F	Catalysis of the reaction: acetyl-CoA + histone H2A L-lysine (position 9) = CoA + histone H2A N6-acetyl-L-lysine (position 9).
44013	H2B histone acetyltransferase activity	F	Catalysis of the reaction: acetyl-CoA + histone H2B L-lysine = CoA + histone H2B N6-acetyl-L-lysine.
44014	histone acetyltransferase activity (H2B-K5 specific)	F	Catalysis of the reaction: acetyl-CoA + histone H2B L-lysine (position 5) = CoA + histone H2B N6-acetyl-L-lysine (position 5).
44015	histone acetyltransferase activity (H2B-K12 specific)	F	Catalysis of the reaction: acetyl-CoA + histone H2B L-lysine (position 12) = CoA + histone H2B N6-acetyl-L-lysine (position 12).
44016	histone acetyltransferase activity (H3-K4 specific)	F	Catalysis of the reaction: acetyl-CoA + histone H3 L-lysine (position 4) = CoA + histone H3 N6-acetyl-L-lysine (position 4).
44017	histone acetyltransferase activity (H3-K27 specific)	F	Catalysis of the reaction: acetyl-CoA + histone H3 L-lysine (position 27) = CoA + histone H3 N6-acetyl-L-lysine (position 27).
44018	histone acetyltransferase activity (H3-K36 specific)	F	Catalysis of the reaction: acetyl-CoA + histone H3 L-lysine (position 36) = CoA + histone H3 N6-acetyl-L-lysine (position 36).
44019	histone acetyltransferase activity (H3-K72 specific)	F	Catalysis of the reaction: acetyl-CoA + histone H3 L-lysine (position 72) = CoA + histone H3 N6-acetyl-L-lysine (position 72).
44020	histone methyltransferase activity (H4-R3 specific)	F	Catalysis of the reaction: S-adenosyl-L-methionine + (histone H4)-arginine (position 3) = S-adenosyl-L-homocysteine + (histone H4)-N-methyl-arginine (position 3). This reaction is the addition of a methyl group to arginine at position 3 of histone H4.
44022	histone kinase activity (H3-S28 specific)	F	Catalysis of the transfer of a phosphate group to the serine-28 residue of the N-terminal tail of histone H3.
44023	histone kinase activity (H4-S1 specific)	F	Catalysis of the transfer of a phosphate group to the serine-1 residue of the N-terminal tail of histone H4.
44024	histone kinase activity (H2A-S1 specific)	F	Catalysis of the transfer of a phosphate group to the serine-1 residue of the N-terminal tail of histone H2A.
44025	histone kinase activity (H2B-S14 specific)	F	Catalysis of the transfer of a phosphate group to the serine-14 or an equivalent residue of the N-terminal tail of histone H2B.
44026	DNA hypermethylation	P	An increase in the epigenetic methylation of cytosine and adenosine residues in DNA.
44027	hypermethylation of CpG island	P	An increase in the epigenetic methylation of cytosine and adenosine residues in a CpG island in DNA. CpG islands are genomic regions that contain a high frequency of the CG dinucleotide and are often associated with the transcription start site of genes.
44028	DNA hypomethylation	P	An decrease in the epigenetic methylation of cytosine and adenosine residues in DNA.
44029	hypomethylation of CpG island	P	An decrease in the epigenetic methylation of cytosine and adenosine residues in a CpG island in DNA. CpG islands are genomic regions that contain a high frequency of the CG dinucleotide and are often associated with the transcription start site of genes.
44030	regulation of DNA methylation	P	Any process that modulates the frequency, rate or extent of the covalent transfer of a methyl group to either N-6 of adenine or C-5 or N-4 of cytosine.
44031	modification by symbiont of host protein by phosphorylation	P	The process in which an organism adds a phosphate group to a protein of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
44032	modulation by symbiont of indole acetic acid levels in host	P	The alteration by an organism of the levels of indole acetic acid in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
44033	multi-organism metabolic process	P	A metabolic process - chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances - which involves more than one organism.
44034	multi-organism biosynthetic process	P	A biosynthetic process - chemical reactions and pathways resulting in the formation of substances - which involves more than one organism.
44035	multi-organism catabolic process	P	A catabolic process - chemical reactions and pathways resulting in the breakdown of substances - which involves more than one organism.
44036	cell wall macromolecule metabolic process	P	The chemical reactions and pathways involving macromolecules forming, or destined to form, part of the cell wall. A cell wall is a rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal and most prokaryotic cells, maintaining their shape and protecting them from osmotic lysis.
44037	multi-organism cell wall macromolecule metabolic process	P	The chemical reactions and pathways involving macromolecules forming, or destined to form, part of a cell wall, involving more than one organism. A cell wall is a rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal and most prokaryotic cells, maintaining their shape and protecting them from osmotic lysis.
44038	cell wall macromolecule biosynthetic process	P	The chemical reactions and pathways resulting in the formation of a macromolecule destined to form part of a cell wall.
44040	multi-organism carbohydrate metabolic process	P	The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y, that involve more than one organism.
44041	multi-organism carbohydrate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y, involving more than one organism.
44042	glucan metabolic process	P	The chemical reactions and pathways involving glucans, polysaccharides consisting only of glucose residues.
44043	multi-organism glucan metabolic process	P	The chemical reactions and pathways involving glucans, polysaccharides consisting only of glucose residues, involving more than one organism.
44044	interaction with host via substance in symbiont surface	P	An interaction with the host organism mediated by a substance on the surface of the other (symbiont) organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
44045	interaction with host via substance in symbiont cell outer membrane	P	An interaction with the host organism mediated by a substance in the symbiont cell outer membrane - a lipid bilayer that forms the outermost layer of the symbiont cell envelope. The host is defined as the larger of the organisms involved in a symbiotic interaction.
44046	interaction with host via substance released outside of symbiont	P	An interaction with the host organism mediated by a substance that is released by the other organism. This includes substances that are released via pathogen cell lysis.
44047	interaction with host via protein secreted by type I secretion system	P	An interaction with the host organism mediated by a substance secreted by the other (symbiont) organism via a type I secretion system. The host is defined as the larger of the organisms involved in a symbiotic interaction.
44048	interaction with host via protein secreted by type V secretion system	P	An interaction with the host organism mediated by a substance secreted by the other (symbiont) organism via a type V secretion system. The host is defined as the larger of the organisms involved in a symbiotic interaction.
44049	interaction with host via protein secreted by type VI secretion system	P	An interaction with the host organism mediated by a substance secreted by the other (symbiont) organism via a type VI secretion system. The host is defined as the larger of the organisms involved in a symbiotic interaction.
44050	interaction with host via substance released by sporangium lysis	P	An interaction with the host organism mediated by a substance released via rupture of symbiont sporangia, structures producing and containing spores. The host is defined as the larger of the organisms involved in a symbiotic interaction.
44051	interaction with host via substance released by symbiont cytolysis	P	An interaction with the host organism mediated by a substance released via cytolysis of symbiont cells. Cytolysis is the rupture of cell membranes and the loss of cytoplasm. The host is defined as the larger of the organisms involved in a symbiotic interaction.
44052	interaction with host via substance released by membrane budding	P	An interaction with the host organism mediated by a substance released via symbiont membrane budding, the evagination of a membrane resulting in formation of a vesicle.
44053	translocation of peptides or proteins into host cell cytoplasm	P	The directed movement of peptides or proteins produced by a symbiont organism to a location within the host cell cytoplasm.
44054	rounding by symbiont of host cells	P	Any process in which an organism causes host cells to change shape and become round.
44055	modulation by symbiont of host system process	P	The alteration by a symbiont organism of the functioning of a system process in the host. A system process is a multicellular organismal process carried out by any of the organs or tissues in an organ system.
44056	modulation by symbiont of host digestive system process	P	The alteration by a symbiont organism of the functioning of a digestive system process, a physical, chemical, or biochemical process carried out by the host organism to break down ingested nutrients into components that may be easily absorbed and directed into metabolism.
44057	regulation of system process	P	Any process that modulates the frequency, rate or extent of a system process, a multicellular organismal process carried out by any of the organs or tissues in an organ system.
44058	regulation of digestive system process	P	Any process that modulates the frequency, rate or extent of a digestive system process, a physical, chemical, or biochemical process carried out by living organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism.
44059	modulation by symbiont of host endocrine process	P	The alteration by a symbiont organism of the functioning of a endocrine process, any of the hormonal, neural, and secretory processes that release products into the blood or lymph, in the host organism.
44060	regulation of endocrine process	P	Any process that modulates the frequency, rate or extent of an endocrine process, a process involving the secretion of or response to endocrine hormones. An endocrine hormone is a hormone released into the circulatory system.
44061	modulation by symbiont of host excretion	P	The alteration by a symbiont organism of the functioning of excretion, the elimination by the host organism of the waste products that arise as a result of metabolic activity.
44062	regulation of excretion	P	Any process that modulates the frequency, rate, or extent of excretion, the elimination by an organism of the waste products that arise as a result of metabolic activity.
44063	modulation by symbiont of host neurological system process	P	The alteration by a symbiont organism of the functioning of a host neurophysiological process, an organ system process carried out by any of the organs or tissues of neurological system.
44064	modulation by symbiont of host respiratory system process	P	The alteration by a symbiont organism of the functioning of a respiratory system process, an organ system process carried out by any of the organs or tissues of the respiratory system.
44065	regulation of respiratory system process	P	Any process that modulates the frequency, rate or extent of a respiratory system process, an organ system process carried out by any of the organs or tissues of the respiratory system.
44066	modification by symbiont of host cell nucleus	P	The process in which a symbiont organism effects a change in the structure or function of its host cell nucleus.
44067	modification by symbiont of host intercellular junctions	P	The process in which a symbiont organism effects a change in the structure or function of its host intercellular junction, a specialized region of connection between two cells.
44068	modulation by symbiont of host cellular process	P	Any process in which a symbiont organism modulates the frequency, rate or extent of a cellular process, any process that is carried out at the cellular level, but not necessarily restricted to a single cell, in its host organism.
44069	modulation by symbiont of host anion transport	P	The process in which a symbiont organism modulates the anion transport, the directed movement of anions, atoms or small molecules with a net negative charge, into, out of or within a cell, or between cells, of its host organism.
44070	regulation of anion transport	P	Any process that modulates the frequency, rate or extent of the directed movement of anions, atoms or small molecules with a net negative charge into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
44071	modulation by symbiont of host cell cycle	P	The process in which a symbiont organism effects a change in its host's cell cycle through direct interactions with the host cell macromolecular machinery.
44072	negative regulation by symbiont of host cell cycle	P	The process in which a symbiont organism stops, prevents or reduces the rate or extent of its host's progression through its cell cycle via direct interactions with the host cell macromolecular machinery.
44073	modulation by symbiont of host translation	P	The process in which a symbiont organism effects a change in translation, the chemical reactions and pathways resulting in the formation of a protein, in its host organism.
44074	negative regulation by symbiont of host translation	P	The process in which a symbiont organism stops, prevents, or reduces the frequency, rate or extent of translation, the chemical reactions and pathways resulting in the formation of a protein, in its host organism.
44075	modulation by symbiont of host vacuole organization	P	Any process in which a symbiont organism modulates the frequency, rate or extent of vacuole organization in its host organism.
44076	positive regulation by symbiont of host vacuole organization	P	The process in which a symbiont organism activates or increases the frequency, rate or extent of vacuole organization in its host organism.
44077	modulation by symbiont of host receptor-mediated endocytosis	P	The process in which a symbiont organism modulates the frequency, rate or extent of receptor mediated endocytosis, the uptake of external materials by cells, utilizing receptors to ensure specificity of transport, in its host organism.
44078	positive regulation by symbiont of host receptor-mediated endocytosis	P	Any process in which a symbiont organism activates or increases the frequency, rate or extent of receptor mediated endocytosis, the uptake of external materials by cells, utilizing receptors to ensure specificity of transport, in its host organism.
44079	modulation by symbiont of host neurotransmitter secretion	P	Any process in which a symbiont organism modulates the frequency, rate or extent of the regulated release of a neurotransmitter from a cell in its host organism.
44080	modulation by symbiont of host cGMP-mediated signal transduction	P	Any process in which a symbiont organism modulates the rate, frequency or extent of cGMP-mediated signaling in its host organism. cGMP-mediated signaling is a series of molecular signals in which a cell uses cyclic GMP to convert an extracellular signal into a response.
44081	modulation by symbiont of host nitric oxide-mediated signal transduction	P	Any process in which a symbiont organism modulates the rate, frequency or extent of nitric oxide mediated signal transduction in its host organism. Nitric oxide mediated signal transduction is a series of molecular signals mediated by the detection of nitric oxide (NO).
44082	modulation by symbiont of host small GTPase mediated signal transduction	P	Any process in which a symbiont organism modulates the frequency, rate or extent of small GTPase mediated signal transduction in its host organism.
44083	modulation by symbiont of host Rho protein signal transduction	P	Any process in which a symbiont organism modulates the frequency, rate or extent of Rho protein signal transduction in its host organism.
44084	host cell membrane pore complex	C	Any small opening in a host cell membrane that allows the passage of gases and/or liquids, composed of host proteins.
44085	cellular component biogenesis	P	A process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cellular component. Includes biosynthesis of constituent macromolecules, and those macromolecular modifications that are involved in synthesis or assembly of the cellular component.
44087	regulation of cellular component biogenesis	P	Any process that modulates the frequency, rate or extent of cellular component biogenesis, a process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cellular component.
44088	regulation of vacuole organization	P	Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a vacuole.
44089	positive regulation of cellular component biogenesis	P	Any process that activates or increases the frequency, rate or extent of cellular component biogenesis, a process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cellular component.
44090	positive regulation of vacuole organization	P	Any process that activates or increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of a vacuole.
44091	membrane biogenesis	P	A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a membrane.
44092	negative regulation of molecular function	P	Any process that stops or reduces the rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding.
44093	positive regulation of molecular function	P	Any process that activates or increases the rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding.
44094	host cell nuclear part	C	Any constituent part of a host cell's nucleus, a membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. The host is the larger of the organisms involved in a symbiotic interaction.
44095	host cell nucleoplasm	C	That part of a host cell's nuclear content other than the chromosomes or the nucleolus. The host is the larger of the organisms involved in a symbiotic interaction.
44096	type IV pilus	C	A short filamentous structure on the surface of a bacterial cell distinguished from other pili by post-translational N-methylation of the pilin monomers.
44097	secretion by the type IV secretion system	P	The controlled release of proteins or DNA by a cell, via the type IV secretion system.
44098	DNA secretion by the type IV secretion system	P	The controlled release of DNA by a cell, via the type IV secretion system.
44099	polar tube	C	A highly specialized structure unique to microsporidia that is required for host cell invasion. In the spore, the polar tube is connected at the anterior end, and then coils around the sporoplasm. Upon appropriate environmental stimulation, the polar tube rapidly discharges out of the spore, pierces a cell membrane and serves as a conduit for sporoplasm passage into the new host cell.
44100	sporoplasm	C	The complex infective apparatus corresponding to the central mass of cytoplasm within a spore that is injected into a host cell by various parasitic microorganisms.
44101	(R)-citramalyl-CoA lyase activity	F	Catalysis of the reaction: (R)-citramalyl-CoA = pyruvate + acetyl-CoA.
44102	purine deoxyribosyltransferase activity	F	Catalysis of deoxyribose exchange between purine deoxyribonucleoside as a donor and purine base as an acceptor.
44103	L-arabinose 1-dehydrogenase (NADP+) activity	F	Catalysis of the reaction: L-arabinose + NADP+ = L-arabinono-1,4-lactone + NADPH + H+.
44104	2,5-dioxovalerate dehydrogenase (NAD+) activity	F	Catalysis of the reaction: 2,5-dioxopentanoate + NAD+ + H2O = 2-oxoglutarate + NADH + H+.
44105	L-xylulose reductase (NAD+) activity	F	Catalysis of the reaction: xylitol + NAD+ = L-xylulose + NADH + H+.
44106	cellular amine metabolic process	P	The chemical reactions and pathways involving any organic compound that is weakly basic in character and contains an amino or a substituted amino group, as carried out by individual cells. Amines are called primary, secondary, or tertiary according to whether one, two, or three carbon atoms are attached to the nitrogen atom.
44107	cellular alcohol metabolic process	P	The chemical reactions and pathways involving alcohols, any of a class of compounds containing one or more hydroxyl groups attached to a saturated carbon atom, as carried out by individual cells.
44108	cellular alcohol biosynthetic process	P	The chemical reactions and pathways resulting in the formation of alcohols, any of a class of compounds containing one or more hydroxyl groups attached to a saturated carbon atom, carried out at the level of an individual cell.
44109	cellular alcohol catabolic process	P	The chemical reactions and pathways resulting in the breakdown of alcohols, any of a class of compounds containing one or more hydroxyl groups attached to a saturated carbon atom, occurring at the level of the individual cell.
44110	growth involved in symbiotic interaction	P	The increase in size or mass of an organism occurring when the organism is in a symbiotic interaction.
44111	development involved in symbiotic interaction	P	The progression of an organism from an initial condition to a later condition, occurring when the organism is in a symbiotic interaction.
44112	growth in other organism involved in symbiotic interaction	P	The increase in size or mass of an organism, occurring within the cells or tissues of a second organism, where the two organisms are in a symbiotic interaction. This may (but not necessarily) include a filamentous growth form, and also can include secretion of proteases and lipases to break down the tissue of the second organism.
44113	development in other organism involved in symbiotic interaction	P	The progression of an organism from an initial condition to a later condition, occurring within the cells or tissues of a second organism, where the two organisms are in a symbiotic interaction. This may (but not necessarily) include a filamentous growth form, and also can include secretion of proteases and lipases to break down the tissue of the second organism.
44114	development of symbiont in host	P	The progression of an organism from an initial condition to a later condition, occurring within the cells or tissues of the host organism. This may (but not necessarily) include a filamentous growth form, and also can include secretion of proteases and lipases to break down host tissue. The host is defined as the larger of the organisms involved in a symbiotic interaction.
44115	development of symbiont involved in interaction with host	P	The progression of an organism from an initial condition to a later condition, occurring in, on or near the exterior of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
44116	growth of symbiont involved in interaction with host	P	The increase in size or mass of an organism, occurring in, on or near the exterior of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
44117	growth of symbiont in host	P	The increase in size or mass of an organism, occurring within the cells or tissues of the host organism. This may (but not necessarily) include a filamentous growth form, and also can include secretion of proteases and lipases to break down host tissue. The host is defined as the larger of the organisms involved in a symbiotic interaction.
44118	development of symbiont in host cell	P	The progression of the symbiont from an initial condition to a later condition, occurring in its host's cell. The host is defined as the larger of the organisms involved in a symbiotic interaction.
44119	growth of symbiont in host cell	P	The increase in size or mass of symbiont, occurring in its host's cell. The host is defined as the larger of the organisms involved in a symbiotic interaction.
44120	development of symbiont in host organelle	P	The progression of the symbiont from an initial condition to a later condition, occurring in its host's organelle. The host is defined as the larger of the organisms involved in a symbiotic interaction.
44121	growth of symbiont in host organelle	P	The increase in size or mass of a symbiont, occurring in its host's organelle. The host is defined as the larger of the organisms involved in a symbiotic interaction.
44122	development of symbiont in host vascular tissue	P	The progression of the symbiont from an initial condition to a later condition, occurring in its host's vascular tissue. The host is defined as the larger of the organisms involved in a symbiotic interaction.
44123	growth of symbiont in host vascular tissue	P	The increase in size or mass of symbiont, occurring in its host's vascular tissue. The host is defined as the larger of the organisms involved in a symbiotic interaction.
44124	development of symbiont in host intercellular space	P	The progression of the symbiont from an initial condition to a later condition, occurring in its host's intercellular space. The host is defined as the larger of the organisms involved in a symbiotic interaction.
44125	growth of symbiont in host intercellular space	P	The increase in size or mass of symbiont, occurring in its host's intercellular space. The host is defined as the larger of the organisms involved in a symbiotic interaction.
44126	regulation of growth of symbiont in host	P	Any process in which the symbiont regulates the increase in its size or mass within the cells or tissues of the host organism. This may (but not necessarily) include a filamentous growth form, and also can include secretion of proteases and lipases to break down. The host is defined as the larger of the organisms involved in the symbiotic interaction.
44127	regulation of development of symbiont in host	P	Any process in which the symbiont regulates its progression from an initial condition to a later condition, within the cells or tissues of the host organism. This may (but not necessarily) include a filamentous growth form, and also can include secretion of proteases and lipases to break down. The host is defined as the larger of the organisms involved in the symbiotic interaction.
44128	positive regulation of growth of symbiont in host	P	Any process in which the symbiont activates, maintains or increases its size or mass within the cells or tissues of the host organism. The host is defined as the larger of the organisms involved in the symbiotic interaction.
44129	positive regulation of development of symbiont in host	P	Any process in which the symbiont activates or maintains its progression from an initial condition to a later condition, within the cells or tissues of the host organism. The host is defined as the larger of the organisms involved in the symbiotic interaction.
44130	negative regulation of growth of symbiont in host	P	Any process in which the symbiont stops, prevents or reduces its increase in size or mass within the cells or tissues of the host organism. The host is defined as the larger of the organisms involved in the symbiotic interaction.
44131	negative regulation of development of symbiont in host	P	Any process in which the symbiont stops, prevents or reduces its progression from an initial condition to a later condition, within the cells or tissues of the host organism. The host is defined as the larger of the organisms involved in the symbiotic interaction.
44132	development of symbiont on or near host	P	The progression of a symbiont from an initial condition to a later condition, within the cells or tissues of its host organism.
44133	growth of symbiont on or near host	P	The increase in size or mass of a symbiont within the cells or tissues of its host organism.
44134	development of symbiont on or near host phyllosphere	P	The progression of the symbiont from an initial condition to a later condition, occurring on or near its host phyllosphere. The host phyllosphere is defined as total above-ground surfaces of a plant as a habitat for symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction.
44135	growth of symbiont on or near host phyllosphere	P	The increase in size or mass of symbiont occurring on or near its host phyllosphere. The host phyllosphere is defined as total above-ground surfaces of a plant as a habitat for symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction.
44136	development of symbiont on or near host rhizosphere	P	The progression of the symbiont from an initial condition to a later condition, occurring on or near its host rhizosphere. The host rhizosphere is defined as total below-ground surfaces of a plant as a habitat for its symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction.
44137	growth of symbiont on or near host rhizosphere	P	The increase in size or mass of symbiont occurring on or near its host rhizosphere. The host rhizosphere is defined as total below-ground surfaces of a plant as a habitat for its symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction.
44138	modulation of development of symbiont on or near host	P	Any process in which the symbiont regulates its progression from an initial condition to a later condition, on or near the cells or tissues of the host organism.
44139	modulation of growth of symbiont on or near host	P	Any process in which the symbiont regulates the increase in its size or mass on or near the cells or tissues of the host organism.
44140	negative regulation of growth of symbiont on or near host surface	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the increase in the symbiont's size or mass on or near the cells or tissues of the host organism.
44141	negative regulation of development of symbiont on or near host surface	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the symbiont's progression from an initial condition to a later condition, on or near the cells or tissues of the host organism.
44142	positive regulation of growth of symbiont on or near host surface	P	Any process that activates or increases the frequency, rate or extent of the symbiont's increase in size or mass on or near the cells or tissues of the host organism.
44143	positive regulation of development of symbiont on or near host surface	P	Any process that activates or increases the frequency, rate or extent of the symbiont's progression from an initial condition to a later condition, on or near the cells or tissues of the host organism.
44144	modulation of growth of symbiont involved in interaction with host	P	Any process that modulates the frequency, rate or extent of the increase in size or mass of an organism occurring in, on or near the exterior of its host organism.
44145	modulation of development of symbiont involved in interaction with host	P	Any process that modulates the frequency, rate or extent of the progression of an organism from an initial condition to a later condition, occurring in, on or near the exterior of its host organism.
44146	negative regulation of growth of symbiont involved in interaction with host	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the increase in size or mass of an organism occurring in, on or near the exterior of its host organism.
44147	negative regulation of development of symbiont involved in interaction with host	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the progression of an organism from an initial condition to a later condition, occurring in, on or near the exterior of its host organism.
44148	positive regulation of growth of symbiont involved in interaction with host	P	Any process that activates or increases the frequency, rate or extent of the increase in size or mass of an organism occurring in, on or near the exterior of its host organism.
44149	positive regulation of development of symbiont involved in interaction with host	P	Any process that activates or increases the frequency, rate or extent of the progression of an organism from an initial condition to a later condition, occurring in, on or near the exterior of its host organism.
44150	development of organism on or near symbiont surface	P	The progression of an organism from an initial condition to a later condition, occurring on or near the exterior of its symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.
44151	growth of organism on or near symbiont surface	P	The increase in size or mass of an organism occurring on or near the exterior of its symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.
44152	development on or near surface of other organism involved in symbiotic interaction	P	The progression of an organism from an initial condition to a later condition, occurring on or near the exterior of a second organism, where the two organisms are in a symbiotic interaction.
44153	growth on or near surface of other organism involved in symbiotic interaction	P	The increase in size or mass of an organism occurring on or near the exterior of a second organism, where the two organisms are in a symbiotic interaction.
44154	histone H3-K14 acetylation	P	The modification of histone H3 by the addition of an acetyl group to a lysine residue at position 14 of the histone.
44155	host caveola	C	A small pit, depression, or invagination, such as any of the minute pits or incuppings of the host cell membrane formed during pinocytosis, that communicates with the outside of a host cell and extends inward, indenting the host cytoplasm and the host cell membrane. Such caveolae may be pinched off to form free vesicles within the host cytoplasm. The host is defined as the larger of the organisms involved in a symbiotic interaction.
44156	host cell junction	C	A plasma membrane part that forms a specialized region of connection between two host cells or between a host cell and the host extracellular matrix. At a host cell junction, anchoring proteins extend through the host plasma membrane to link cytoskeletal proteins in one cell to cytoskeletal proteins in neighboring cells or to proteins in the extracellular matrix.
44157	host cell projection	C	A prolongation or process extending from a host cell, e.g. a flagellum or axon.
44158	host cell wall	C	The rigid or semi-rigid envelope lying outside the host cell membrane of plant, fungal, and most prokaryotic cells, maintaining their shape and protecting them from osmotic lysis. In plants it is made of cellulose and, often, lignin; in fungi it is composed largely of polysaccharides; in bacteria it is composed of peptidoglycan.
44159	host thylakoid	C	A membranous cellular structure within the host cell that bears the photosynthetic pigments in plants, algae, and cyanobacteria. In cyanobacteria thylakoids are of various shapes and are attached to, or continuous with, the host plasma membrane. In eukaryotic host cells they are flattened, membrane-bounded disk-like structures located in the chloroplasts; in the chloroplasts of higher plants the thylakoids form dense stacks called grana. Isolated thylakoid preparations can carry out photosynthetic electron transport and the associated phosphorylation.
44160	host thylakoid membrane	C	The pigmented membrane of any host thylakoid.
44161	host cell cytoplasmic vesicle	C	A vesicle formed of membrane or protein, found in the cytoplasm of a host cell.
44162	host cell cytoplasmic vesicle membrane	C	The lipid bilayer surrounding a host cell cytoplasmic vesicle.
44163	host cytoskeleton	C	Any of the various filamentous elements that form the internal framework of host cells, and typically remain after treatment of the cells with mild detergent to remove membrane constituents and soluble components of the host cytoplasm. The term embraces intermediate filaments, microfilaments, microtubules, the microtrabecular lattice, and other structures characterized by a polymeric filamentous nature and long-range order within the host cell. The various elements of the host cytoskeleton not only serve in the maintenance of host cellular shape but also have roles in other host cellular functions, including cellular movement, cell division, endocytosis, and movement of organelles.
44164	host cell cytosol	C	The part of the host cell cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
44165	host cell endoplasmic reticulum	C	The irregular network of unit membranes, visible only by electron microscopy, that occurs in the host cell cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The host ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
44166	host cell endoplasmic reticulum lumen	C	The volume enclosed by the membranes of the host cell endoplasmic reticulum.
44167	host cell endoplasmic reticulum membrane	C	The lipid bilayer surrounding the host cell endoplasmic reticulum.
44168	host cell rough endoplasmic reticulum	C	The irregular network of unit membranes, visible only by electron microscopy, that occurs in the host cell cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The host rough ER has ribosomes adhering to the outer surface.
44169	host cell rough endoplasmic reticulum membrane	C	The lipid bilayer surrounding the host cell rough endoplasmic reticulum.
44170	host cell smooth endoplasmic reticulum	C	The irregular network of unit membranes, visible only by electron microscopy, that occurs in the host cell cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The host smooth ER has no ribosomes adhering to the outer surface.
44171	host cell smooth endoplasmic reticulum membrane	C	The lipid bilayer surrounding the host cell smooth endoplasmic reticulum.
44172	host cell endoplasmic reticulum-Golgi intermediate compartment	C	A complex system of membrane-bounded compartments located between host cell endoplasmic reticulum (ER) and the host Golgi complex, with a distinctive membrane protein composition; involved in ER-to-Golgi transport.
44173	host cell endoplasmic reticulum-Golgi intermediate compartment membrane	C	The lipid bilayer surrounding any of the compartments of the host cell ER-Golgi intermediate compartment system.
44174	host cell endosome	C	A membrane-bounded organelle that carries materials newly ingested by endocytosis. It passes many of the materials to host cell lysosomes for degradation.
44175	host cell endosome membrane	C	The lipid bilayer surrounding a host cell endosome.
44176	host cell filopodium	C	Thin, stiff protrusion extended by the leading edge of a motile host cell such as a crawling fibroblast or amoeba, or an axonal growth cone; usually approximately 0.1 um wide, 5-10 um long, can be up to 50 um long in axon growth cones; contains a loose bundle of about 20 actin filaments oriented with their plus ends pointing outward.
44177	host cell Golgi apparatus	C	A compound membranous cytoplasmic organelle of eukaryotic host cells, consisting of flattened, ribosome-free vesicles arranged in a more or less regular stack.
44178	host cell Golgi membrane	C	The lipid bilayer surrounding any of the compartments of the host cell Golgi apparatus.
44179	hemolysis in other organism	P	The cytolytic destruction of red blood cells, with the release of intracellular hemoglobin, in one organism by another.
44180	filamentous growth of a unicellular organism	P	The process in which a unicellular organism grows in a threadlike, filamentous shape.
44181	filamentous growth of a multicellular organism	P	The process in which a multicellular organism grows in a threadlike, filamentous shape.
44182	filamentous growth of a population of unicellular organisms	P	The process in which a group of unicellular organisms grow in a threadlike, filamentous shape.
44183	protein binding involved in protein folding	F	Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules) that contributes to the process of protein folding.
44184	host cell late endosome	C	A prelysosomal endocytic organelle differentiated from host early endosomes by lower lumenal pH and different protein composition. Host late endosomes are more spherical than early endosomes and are mostly juxtanuclear, being concentrated near the microtubule organizing center.
44185	host cell late endosome membrane	C	The lipid bilayer surrounding a host cell late endosome.
44186	host cell lipid particle	C	Any particle of coalesced lipids in the cytoplasm of a host cell. May include associated proteins.
44187	host cell lysosome	C	A small lytic vacuole that has cell cycle-independent morphology and is found in most host animal cells and that contains a variety of hydrolases, most of which have their maximal activities in the pH range 5-6. The contained enzymes display latency if properly isolated. About 40 different lysosomal hydrolases are known and host cell lysosomes have a great variety of morphologies and functions.
44188	host cell lysosomal membrane	C	The lipid bilayer surrounding the host cell lysosome and separating its contents from the host cell cytoplasm.
44190	host cell mitochondrial envelope	C	The double lipid bilayer enclosing the host cell mitochondrion and separating its contents from the host cell cytoplasm; includes the intermembrane space.
44191	host cell mitochondrial membrane	C	Either of the lipid bilayers that surround the host cell mitochondrion and form the host cell mitochondrial envelope.
44192	host cell mitochondrial inner membrane	C	The inner, i.e. lumen-facing, lipid bilayer of the host cell mitochondrial envelope. It is highly folded to form cristae.
44193	host cell mitochondrial outer membrane	C	The outer, i.e. cytoplasm-facing, lipid bilayer of the host cell mitochondrial envelope.
44194	cytolytic granule	C	A specialized secretory lysosome that is present in cells with cytolytic capability such as cytotoxic T lymphocytes and natural killer cells. Cytolytic granules mediate the storage and regulated excretion of lytic molecules for killing of target cells.
44195	nucleoplasmic reticulum	C	Long, dynamic tubular channels, formed by invagination of the nuclear envelope, that extend deep into the nucleoplasm. The channels have an underlying lamina and are implicated in functioning in signaling and transport.
44196	host cell nucleolus	C	A small, dense body one or more of which are present in the nucleus of eukaryotic host cells.
44197	Rel homology domain binding	F	Interacting selectively and non-covalently with a Rel Homology Domain (RHD) of a protein. The RHD is found in a family of eukaryotic transcription factors, which includes NF-kappaB, Dorsal, Relish and NFAT.
44198	zf-TRAF domain binding	F	Interacting selectively and non-covalently with a TRAF-type zinc finger domain of a protein.
44199	host cell nuclear envelope	C	The double lipid bilayer enclosing the host nucleus and separating its contents from the rest of the host cytoplasm; includes the intermembrane space, a gap of width 20-40 nm (also called the perinuclear space).
44200	host cell nuclear membrane	C	Either of the lipid bilayers that surround the host nucleus and form the nuclear envelope; excludes the intermembrane space.
44201	host cell nuclear inner membrane	C	The inner, i.e. lumen-facing, lipid bilayer of the host nuclear envelope.
44202	host cell nuclear outer membrane	C	The outer, i.e. cytoplasm-facing, lipid bilayer of the host nuclear envelope; continuous with the endoplasmic reticulum of the host cell and sometimes studded with ribosomes.
44203	host cell nuclear lamina	C	The fibrous, electron-dense layer lying on the nucleoplasmic side of the inner membrane of a host cell nucleus, composed of lamin filaments.
44204	host cell nuclear matrix	C	The dense fibrillar network lying on the inner side of the host nuclear membrane.
44205	'de novo' UMP biosynthetic process	P	The chemical reactions and pathways resulting in the formation of UMP, uridine monophosphate, starting with the synthesis of (S)-dihydroorotate from bicarbonate; UMP biosynthesis may either occur via reduction by quinone, NAD(+) or oxygen.
44206	UMP salvage	P	Any process which produces UMP, uridine monophosphate, from derivatives of it (e.g. cytidine, uridine, cytosine) without de novo synthesis.
44207	translation initiation ternary complex	C	A ribonucleoprotein complex that contains aminoacylated initiator methionine tRNA, GTP, and initiation factor 2 (either eIF2 in eukaryotes, or IF2 in prokaryotes). In prokaryotes, fMet-tRNA (initiator) is used rather than Met-tRNA (initiator).
44208	'de novo' AMP biosynthetic process	P	The chemical reactions and pathways resulting in the formation of adenosine monophosphate (AMP) from inosine 5'-monophosphate (IMP).
44209	AMP salvage	P	The chemical reactions and pathways resulting in the formation of adenosine monophosphate (AMP) from derivatives of it (either adenine, ADP or adenosine 3',5'-bisphosphate) without de novo synthesis.
44210	'de novo' CTP biosynthetic process	P	The chemical reactions and pathways resulting in the formation of cytidine 5'-triphosphate (CTP) from simpler components.
44211	CTP salvage	P	Any process which produces cytidine 5'-triphosphate (CTP) from derivatives of it, without de novo synthesis.
44212	transcription regulatory region DNA binding	F	Interacting selectively and non-covalently with a DNA region that regulates the transcription of a region of DNA, which may be a gene, cistron, or operon. Binding may occur as a sequence specific interaction or as an interaction observed only once a factor has been recruited to the DNA by other factors.
44213	intronic transcription regulatory region DNA binding	F	Interacting selectively and non-covalently with an intronic DNA region that regulates the transcription of the transcript it is contained within.
44214	spanning component of plasma membrane	C	The component of the plasma membrane consisting of gene products and protein complexes that have some part that spans both leaflets of the membrane.
44215	other organism	C	A secondary organism with which the first organism is interacting.
44216	other organism cell	C	A cell of a secondary organism with which the first organism is interacting.
44217	other organism part	C	Any constituent part of a secondary organism with which the first organism is interacting.
44218	other organism cell membrane	C	The cell membrane of a secondary organism with which the first organism is interacting.
44219	host cell plasmodesma	C	A fine cytoplasmic channel, found in all higher plants, that connects the cytoplasm of one host cell to that of an adjacent host cell.
44220	host cell perinuclear region of cytoplasm	C	The host cell cytoplasm situated near, or occurring around, the host nucleus.
44221	host cell synapse	C	The junction between a nerve fiber of one host neuron and another host neuron or muscle fiber or glial cell; the site of interneuronal communication.
44222	anammoxosome	C	An intracytoplasmic membrane-bounded compartment in anaerobic ammonium oxidation (anammox) bacteria, is the site of anammox catabolism.
44223	pirellulosome	C	A cytoplasmic structure found in bacterial phyla Planctomycetes and Verrucomicrobia containing a condensed nucleoid and ribosomes and surrounded by an intracytoplasmic membrane. It is surrounded by ribosome-free cytoplasm, in a compartment called the paryphoplasm.
44224	juxtaparanode region of axon	C	A region of an axon near a node of Ranvier that is between the paranode and internode regions.
44225	apical pole of neuron	C	Portion of a neuron cell soma closest to the point where the apical dendrite emerges.
44226	basal pole of neuron	C	Portion of a neuron cell soma closest to the point where the basilar dendrite emerges.
44227	methane-oxidizing organelle	C	A cytoplasmic, membrane-bounded compartment found within Methanotrophic bacteria that contains enzymes and electron transfer proteins for methane catabolism. This structure is analogous to the thylakoid of Cyanobacteria and the anammoxosome of anaerobic ammonium oxidation organisms.
44228	host cell surface	C	The external part of the host cell wall and/or host plasma membrane.
44229	host cell periplasmic space	C	The region between the inner (cytoplasmic) and outer host membrane (Gram-negative Bacteria) or inner host membrane and host cell wall (Fungi).
44230	host cell envelope	C	An envelope that surrounds a bacterial host cell and includes the host cytoplasmic membrane and everything external, encompassing the host periplasmic space, host cell wall, and host outer membrane if present.
44231	host cell presynaptic membrane	C	A specialized area of membrane of the host axon terminal that faces the plasma membrane of the host neuron or muscle fiber with which the axon terminal establishes a synaptic junction; many host synaptic junctions exhibit structural presynaptic characteristics, such as conical, electron-dense internal protrusions, that distinguish it from the remainder of the axon plasma membrane.
44232	organelle membrane contact site	C	A zone of apposition between the membranes of two organelles, structured by bridging complexes. Membrane contact sites (MCSs) are specialized for communication, including the efficient traffic of small molecules such as Ca2+ ions and lipids, as well as enzyme-substrate interactions.
44233	ER-mitochondrion membrane contact site	C	A zone of apposition between endoplasmic-reticulum and mitochondrial membranes, structured by bridging complexes. These contact sites are thought to facilitate inter-organelle calcium and phospholipid exchange.
44236	multicellular organism metabolic process	P	The chemical reactions and pathways in a single multicellular organism that occur at the tissue, organ, or organismal level. These processes, unlike cellular metabolism, can include transport of substances between cells when that transport is required.
44237	cellular metabolic process	P	The chemical reactions and pathways by which individual cells transform chemical substances.
44238	primary metabolic process	P	The chemical reactions and pathways involving those compounds which are formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism.
44239	salivary polysaccharide catabolic process	P	The chemical reactions and pathways resulting in the breakdown of polysaccharides by salivary amylase. Salivary amylase is released by salivary glands, usually in the mouth.
44240	multicellular organismal lipid catabolic process	P	The chemical reactions and pathways resulting in the breakdown of lipids, occurring at the tissue, organ, or organismal level of a multicellular organism.
44241	lipid digestion	P	The whole of the physical, chemical, and biochemical processes carried out by living organisms to break down ingested lipids into components that may be easily absorbed and directed into metabolism.
44242	cellular lipid catabolic process	P	The chemical reactions and pathways resulting in the breakdown of lipids, as carried out by individual cells.
44243	multicellular organismal catabolic process	P	The chemical reactions and pathways resulting in the breakdown of substances in multicellular organisms that occur at the tissue, organ, or organismal level. These processes, unlike cellular metabolism, can include transport of substances between cells when that transport is required.
44244	multicellular organismal polysaccharide catabolic process	P	The chemical reactions and pathways resulting in the breakdown of polysaccharides, occurring at the tissue, organ, or organismal level of a multicellular organism.
44245	polysaccharide digestion	P	The whole of the physical, chemical, and biochemical processes carried out by living organisms to break down ingested polysaccharides into components that may be easily absorbed and directed into metabolism.
44246	regulation of multicellular organismal metabolic process	P	Any process that modulates the frequency, rate or extent of chemical reactions and pathways in multicellular organisms that occur at the tissue, organ, or organismal level.
44247	cellular polysaccharide catabolic process	P	The chemical reactions and pathways resulting in the breakdown of polysaccharides, polymers of many (typically more than 10) monosaccharide residues linked glycosidically, as carried out by individual cells.
44248	cellular catabolic process	P	The chemical reactions and pathways resulting in the breakdown of substances, carried out by individual cells.
44249	cellular biosynthetic process	P	The chemical reactions and pathways resulting in the formation of substances, carried out by individual cells.
44250	negative regulation of metabolic activity involved in hibernation	P	The slowing of metabolic processes to very low levels in order to conserve energy as a part of hibernation.
44251	protein catabolic process by pepsin	P	The chemical reactions and pathways resulting in the breakdown of a protein by pepsin in the stomach. Pepsin is generated from its precursor pepsinogen, which is activated by hydrolchloric acid (gastric acid).
44252	negative regulation of multicellular organismal metabolic process	P	Any process that stops, prevents or reduces frequency, rate or extent of chemical reactions and pathways in multicellular organisms that occur at the tissue, organ, or organismal level.
44253	positive regulation of multicellular organismal metabolic process	P	Any process that activates or increases frequency, rate or extent of chemical reactions and pathways in multicellular organisms that occur at the tissue, organ, or organismal level.
44254	multicellular organismal protein catabolic process	P	The chemical reactions and pathways resulting in the breakdown of a protein in a multicellular organism, occurring at the tissue, organ, or organismal level.
44255	cellular lipid metabolic process	P	The chemical reactions and pathways involving lipids, as carried out by individual cells.
44256	protein digestion	P	The whole of the physical, chemical, and biochemical processes carried out by living organisms to break down ingested proteins into components that may be easily absorbed and directed into metabolism.
44257	cellular protein catabolic process	P	The chemical reactions and pathways resulting in the breakdown of a protein by individual cells.
44258	intestinal lipid catabolic process	P	The chemical reactions and pathways resulting in the breakdown into fatty acids and monoglycerides of lipids in the small intestine. Lipids are broken down by lipases released by the pancreas.
44259	multicellular organismal macromolecule metabolic process	P	The chemical reactions and pathways involving macromolecules, large molecules including proteins, nucleic acids and carbohydrates, in multicellular organisms occurring at the tissue, organ, or organismal level.
44260	cellular macromolecule metabolic process	P	The chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass, as carried out by individual cells.
44261	multicellular organismal carbohydrate metabolic process	P	The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y, in a single multicellular organism, occurring at the tissue, organ, or organismal level.
44262	cellular carbohydrate metabolic process	P	The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y, as carried out by individual cells.
44263	multicellular organismal polysaccharide metabolic process	P	The chemical reactions and pathways involving polysaccharides, polymers of more than 10 monosaccharide residues joined by glycosidic linkages, in multicellular organisms that occur at the tissue, organ, or organismal level.
44264	cellular polysaccharide metabolic process	P	The chemical reactions and pathways involving polysaccharides, polymers of more than 10 monosaccharide residues joined by glycosidic linkages, as carried out by individual cells.
44265	cellular macromolecule catabolic process	P	The chemical reactions and pathways resulting in the breakdown of a macromolecule, any large molecule including proteins, nucleic acids and carbohydrates, as carried out by individual cells.
44266	multicellular organismal macromolecule catabolic process	P	The chemical reactions and pathways resulting in the breakdown of a macromolecule, any large molecule including proteins, nucleic acids and carbohydrates, in multicellular organisms occurring at the tissue, organ, or organismal level.
44267	cellular protein metabolic process	P	The chemical reactions and pathways involving a specific protein, rather than of proteins in general, occurring at the level of an individual cell. Includes cellular protein modification.
44268	multicellular organismal protein metabolic process	P	The chemical reactions and pathways involving a specific protein, rather than of proteins in general, in multicellular organisms occurring at the tissue, organ, or organismal level.
44269	glycerol ether catabolic process	P	The chemical reactions and pathways resulting in the breakdown of glycerol ethers, any anhydride formed between two organic hydroxy compounds, one of which is glycerol.
44270	cellular nitrogen compound catabolic process	P	The chemical reactions and pathways resulting in the breakdown of organic and inorganic nitrogenous compounds.
44271	cellular nitrogen compound biosynthetic process	P	The chemical reactions and pathways resulting in the formation of organic and inorganic nitrogenous compounds.
44272	sulfur compound biosynthetic process	P	The chemical reactions and pathways resulting in the formation of compounds that contain sulfur, such as the amino acids methionine and cysteine or the tripeptide glutathione.
44273	sulfur compound catabolic process	P	The chemical reactions and pathways resulting in the breakdown of compounds that contain sulfur, such as the amino acids methionine and cysteine or the tripeptide glutathione.
44274	multicellular organismal biosynthetic process	P	The chemical reactions and pathways resulting in the formation of substances in multicellular organisms, occurring at the tissue, organ, or organismal level.
44275	cellular carbohydrate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y, as carried out by individual cells.
44276	multicellular organismal carbohydrate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y, in a single multicellular organism occurring at the tissue, organ, or organismal level.
44277	cell wall disassembly	P	A process that results in the breakdown of the cell wall.
44278	cell wall disruption in other organism	P	A process carried out by an organism that results in the breakdown of the cell wall of a second organism.
44279	other organism membrane	C	A membrane of a secondary organism with which the first organism is interacting.
44280	subplasmalemmal coating	C	Electron dense material observed coating the cytoplasmic face of the plasma membrane in certain regions of a neuron, e.g., the axon initial segment; the nodal membrane at the Node of Ranvier.
44281	small molecule metabolic process	P	The chemical reactions and pathways involving small molecules, any low molecular weight, monomeric, non-encoded molecule.
44282	small molecule catabolic process	P	The chemical reactions and pathways resulting in the breakdown of small molecules, any low molecular weight, monomeric, non-encoded molecule.
44283	small molecule biosynthetic process	P	The chemical reactions and pathways resulting in the formation of small molecules, any low molecular weight, monomeric, non-encoded molecule.
44284	mitochondrial crista junction	C	A tubular structure of relatively uniform size that connects a mitochondrial crista to the mitochondrial inner boundary membrane.
44285	bridge contact site	C	Site of contact between the inner and outer mitochondrial membrane found in neuronal mitochondria; may play a role in maintaining the structural integrity of the inner and outer boundary membranes.
44286	peg and socket contact	C	A cell-cell contact zone that consists of membrane invaginations extending from either cell, which contain tight-, gap-, and adherens junctions. Peg and socket contacts form between endothelial cells and pericytes, and between lens fiber cells.
44288	puncta adhaerentia	C	A small version of the zonula adherens type junction, characterized by a symmetrical adherent point between two cells.
44289	contact site	C	Sites of close apposition of the inner and outer mitochondrial membrane.
44290	mitochondrial intracristal space	C	The space bounded by the mitochondrial cristae membranes, continuous with the intermembrane space.
44291	cell-cell contact zone	C	Extended zone of intimate apposition between two cells containing one or more types of intercellular junctions, e.g., the intercalated disk of muscle.
44292	dendrite terminus	C	A structure at the distal end of a dendrite adapted to carry out a specific function, e.g. dendriole.
44293	dendriole	C	Small dendrites that makes up a brush structure found as the terminal specialization of a dendrite of a unipolar brush cell (UBC).
44294	dendritic growth cone	C	The migrating motile tip of a growing nerve cell dendrite.
44295	axonal growth cone	C	The migrating motile tip of a growing nerve cell axon.
44296	dendritic tuft	C	The terminal specialization found in some types of dendrites which consists of numerous small terminal branches, giving the dendrite a tufted appearance.
44297	cell body	C	The portion of a cell bearing surface projections such as axons, dendrites, cilia, or flagella that includes the nucleus, but excludes all cell projections.
44298	cell body membrane	C	The plasma membrane of a cell that bears surface projections such as axons, dendrites, cilia, or flagella, excluding the plasma membrane on cell projections.
44299	C-fiber	C	The axon of a dorsal root ganglion cell that are responsive to pain and temperature. C-fibers are small in diameter (0.2-1.5 um) and unmyelinated.
44300	cerebellar mossy fiber	C	An axon arising from cerebellar projecting cells in the cochlea, vestibular nuclei, spinal cord, reticular formation, cerebellar nuclei and basilar pontine nuclei. Mossy fibers enter through all three cerebellar peduncles and send collaterals to the deep cerebellar nuclei, then branch in the white matter and terminate in the granule cell layer. Through this branching, a given mossy fiber can innervate several folia. Mossy fibers synapse on granule cells. The synaptic contacts are made at enlargements along the length of the mossy fiber called mossy fiber rosettes. The enlargements of the rosettes give the axons as "mossy" appearance in Golgi stained preparations.
44301	climbing fiber	C	The axon of inferior olive neuron that projects to the cerebellar cortex, largely via the inferior cerebellar peduncle. They range in diameter from 1-3 um and are myelinated until they enter the granule cell layer. They give off collaterals to the deep cerebellar nuclei. They synapse extensively with the dendrites of Purkinje cells in the molecular layer, where each fiber branches repeatedly to "climb" along the Purkinje cell dendritic tree. Each Purkinje cell is innervated by only a single climbing fiber.
44302	dentate gyrus mossy fiber	C	Distinctive, unmyelinated axons produced by granule cells.
44303	axon collateral	C	Any of the smaller branches of an axon that emanate from the main axon cylinder.
44304	main axon	C	The main axonal trunk, as opposed to the collaterals; i.e., excluding collaterals, terminal, spines, or dendrites.
44305	calyx of Held	C	The terminal specialization of a calyciferous axon which forms large synapses in the mammalian auditory central nervous system.
44306	neuron projection terminus	C	The specialized, terminal region of a neuron projection such as an axon or a dendrite.
44307	dendritic branch	C	A dendrite arising from another dendrite.
44308	axonal spine	C	A spine that originates from the axon, usually from the initial segment.
44309	neuron spine	C	A small membranous protrusion, often ending in a bulbous head and attached to the neuron by a narrow stalk or neck.
44310	osmiophilic body	C	A membrane-bounded vesicle found predominantly in Plasmodium female gametocytes, that becomes progressively more abundant as the gametocyte reaches full maturity. These vesicles lie beneath the subpellicular membrane of the gametocyte, and the release of their contents into the parasitophorous vacuole has been postulated to aid in the escape of gametocytes from the erythrocyte after ingestion by the mosquito.
44311	exoneme	C	A dense granule-like organelle of the apical complex of merozoites, released into the parasitophorous vacuole, mediating protease-dependent rupture and parasite exit from the infected erythrocyte.
44312	crystalloid	C	A transient, cytoplasmic organelle found in Plasmodium species that resembles a cytoplasmic inclusion body and whose function is poorly understood. Crystalloids form in ookinetes and disappear after ookinete-to-oocyst transformation.
44313	protein K6-linked deubiquitination	P	A protein deubiquitination process in which a K6-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 6 of the ubiquitin monomers, is removed from a protein.
44314	protein K27-linked ubiquitination	P	A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 27 of the ubiquitin monomers, is added to a protein.
44315	protein secretion by the type VII secretion system	P	The process in which proteins are transferred into the extracellular milieu or directly into host cells, via the type VII protein secretion system.
44316	cone cell pedicle	C	A specialized axon terminus which is produced by retinal cone cells. Pedicles are large, conical, flat end-feet (8-10 micrometers diameter) of the retinal cone axon that lie more or less side by side on the same plane at the outer edge of the outer plexiform layer (OPL).
44317	rod spherule	C	A specialized neuron projection which is the site of synaptic transmission produced by retinal rod cells. Rod spherules are small round enlargements of the axon (3-5 micrometers diameter) or even extensions of the cell body.
44318	L-aspartate:fumarate oxidoreductase activity	F	Catalysis of the reaction: L-aspartate + fumarate = alpha-iminosuccinate + succinate.
44319	wound healing, spreading of cells	P	The migration of a cell along or through a wound gap that contributes to the reestablishment of a continuous surface.
44320	cellular response to leptin stimulus	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a leptin stimulus. Leptin is a hormone manufactured primarily in the adipocytes of white adipose tissue, and the level of circulating leptin is directly proportional to the total amount of fat in the body. It plays a key role in regulating energy intake and energy expenditure, including appetite and metabolism.
44321	response to leptin	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a leptin stimulus. Leptin is a hormone manufactured primarily in the adipocytes of white adipose tissue, and the level of circulating leptin is directly proportional to the total amount of fat in the body. It plays a key role in regulating energy intake and energy expenditure, including appetite and metabolism].
44322	endoplasmic reticulum quality control compartment	C	A subcompartment of the endoplasmic reticulum in which proteins with improper or incorrect folding accumulate. Enzymes in this compartment direct proteins with major folding problems to translocation to the cytosol and degradation, and proteins with minor folding problems to the ER, to interact with chaperon proteins.
44323	retinoic acid-responsive element binding	F	Interacting selectively and non-covalently with a retinoic acid-responsive element, a variable direct repeat of the sequence PuGGTCA spaced by five nucleotides (DR5) found in the promoters of retinoic acid-responsive genes, to which retinoic acid receptors bind.
44324	regulation of transcription involved in anterior/posterior axis specification	P	Any process that modulates the frequency, rate or extent of transcription that contributes to the specification of the anterior/posterior axis.
44325	ion channel binding	F	Interacting selectively and non-covalently with one or more specific sites on an ion channel, a protein complex that spans a membrane and forms a water-filled channel across the phospholipid bilayer allowing selective ion transport down its electrochemical gradient.
44326	dendritic spine neck	C	Part of the dendritic spine that connects the dendritic shaft to the head of the dendritic spine.
44327	dendritic spine head	C	Distal part of the dendritic spine, that carries the post-synaptic density.
44328	canonical Wnt signaling pathway involved in positive regulation of endothelial cell migration	P	The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes involved in the positive regulation of endothelial cell migration.
44329	canonical Wnt signaling pathway involved in positive regulation of cell-cell adhesion	P	The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes involved in the positive regulation of cell to cell adhesion.
44330	canonical Wnt signaling pathway involved in positive regulation of wound healing	P	The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes involved in positive regulation of wound healing.
44331	cell-cell adhesion mediated by cadherin	P	The attachment of one cell to another cell via a cadherin, transmembrane proteins having repeating extracellular calcium ion binding domains.
44332	Wnt signaling pathway involved in dorsal/ventral axis specification	P	The series of molecular signals initiated by binding of Wnt protein to a frizzled family receptor on the surface of the target cell contributing to the establishment, maintenance and elaboration of the dorsal/ventral axis.
44333	Wnt signaling pathway involved in digestive tract morphogenesis	P	The series of molecular signals initiated by binding of Wnt protein to a frizzled family receptor on the surface of the target cell contributing to the generation and the organization of the digestive tract.
44334	canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition	P	The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes involved in the positive regulation of epithelial cell to mesenchymal cell transition.
44335	canonical Wnt signaling pathway involved in neural crest cell differentiation	P	The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes involved in neural crest cell differentiation.
44336	canonical Wnt signaling pathway involved in negative regulation of apoptotic process	P	The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes involved in the negative regulation of apoptotic process.
44337	canonical Wnt signaling pathway involved in positive regulation of apoptotic process	P	The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes involved in the positive regulation of apoptotic process.
44338	canonical Wnt signaling pathway involved in mesenchymal stem cell differentiation	P	The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes involved in mesenchymal stem cell differentiation.
44339	canonical Wnt signaling pathway involved in osteoblast differentiation	P	The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes involved in osteoblast differentiation.
44340	canonical Wnt signaling pathway involved in regulation of cell proliferation	P	The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes that contributes to modulating the rate or frequency of cell proliferation.
44341	sodium-dependent phosphate transport	P	The directed movement of phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore, by a mechanism dependent upon sodium ions.
44342	type B pancreatic cell proliferation	P	The multiplication or reproduction of pancreatic B cells, resulting in the expansion of an pancreatic B cell population. Pancreatic B cell are cells of the pancreas that secrete insulin.
44343	canonical Wnt signaling pathway involved in regulation of type B pancreatic cell proliferation	P	The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes that modulates the rate or frequency of pancreatic B cell proliferation. Pancreatic B cell are cells of the pancreas that secrete insulin.
44344	cellular response to fibroblast growth factor stimulus	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an fibroblast growth factor stimulus.
44345	stromal-epithelial cell signaling involved in prostate gland development	P	The process of transferring information from a stromal cell to an epithelial cell where it is received and interpreted, as part of prostate gland development.
44346	fibroblast apoptotic process	P	Any apoptotic process in a fibroblast, a connective tissue cell which secretes an extracellular matrix rich in collagen and other macromolecules.
44347	cell wall polysaccharide catabolic process	P	The chemical reactions and pathways resulting in the breakdown of cell wall polysaccharides.
44348	plant-type cell wall cellulose catabolic process	P	The chemical reactions and pathways resulting in the breakdown of cellulose, a linear beta1-4 glucan of molecular mass 50-400 kDa with the pyranose units in the -4C1 conformation, which forms part of the cell wall.
44349	DNA excision	P	The removal of a section of DNA from a larger DNA molecule by the making of dual incisions that flank the section to be excised.
44350	micropinocytosis	P	An endocytosis process that results in the uptake of liquid material by cells from their external environment by invagination of the plasma membrane to form uncoated micropinosomes, differentiated from macropinosomes by their smaller size, on average 95 nm.
44351	macropinocytosis	P	An endocytosis process that results in the uptake of liquid material by cells from their external environment by the 'ruffling' of the cell membrane to form heterogeneously sized intracellular vesicles called macropinosomes, which can be up to 5 micrometers in size.
44352	pinosome	C	A membrane-bounded, uncoated intracellular vesicle formed by the process of pinocytosis.
44353	micropinosome	C	A membrane-bounded, uncoated intracellular vesicle formed by the process of micropinocytosis.
44354	macropinosome	C	A membrane-bounded, uncoated intracellular vesicle formed by the process of macropinocytosis.
44355	clearance of foreign intracellular DNA	P	A defense process that protects an organism from invading foreign DNA.
44356	clearance of foreign intracellular DNA by conversion of DNA cytidine to uridine	P	A defense process that protects an organism from invading foreign DNA. The process begins by the deamination of foreign double-stranded DNA cytidines to uridines. These atypical DNA nucleosides are then converted by a uracil DNA glycosylase to abasic lesions, and the process ends with the degradation of the foreign DNA.
44357	regulation of rRNA stability	P	Any process that modulates the propensity of rRNA molecules to degradation. Includes processes that both stabilize and destabilize rRNAs.
44358	envenomation resulting in hemorrhagic damage to other organism	P	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with vascular damage and hemorrhage in the bitten organism.
44359	modulation of molecular function in other organism	P	The process in which an organism effects a change in the function of proteins in a second organism.
44360	modulation of voltage-gated potassium channel activity in other organism	P	Any process in which an organism effects a change in the frequency, rate or extent of the activity of a voltage-gated potassium channel in another organism.
44361	negative regulation of voltage-gated potassium channel activity in other organism	P	Any process in which an organism stops, prevents or reduces the frequency, rate or extent of the activity of a voltage-gated potassium channel in another organism.
44362	negative regulation of molecular function in other organism	P	Any process in which an organism stops, prevents or reduces the frequency, rate or extent of the function of proteins in a second organism.
44363	modulation of potassium channel activity in other organism	P	Any process in which an organism effects a change in the frequency, rate or extent of the activity of a potassium channel in another organism.
44364	disruption of cells of other organism	P	A process in which an organism has a negative effect on the functioning of the second organism's cells.
44365	envenomation resulting in modulation of platelet aggregation in other organism	P	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with a resultant change to the frequency, rate or extent of platelet aggregation in the bitten organism.
44366	feeding on or from other organism	P	The process of consuming the whole or part of another organism for the purposes of nutrition.
44367	feeding from tissue of other organism	P	The behaviour of consuming part of another organism for the purposes of nutrition via a particular tissue e.g. vascular tissue.
44368	feeding from vascular tissue of another organism	P	The behaviour of consuming part of another organism for the purposes of nutrition via a vascular tissue.
44369	feeding on blood of other organism	P	The behaviour of feeding on the blood of another organism via specialized mouth parts and chemical agents used to penetrate vascular structures in the skin of hosts.
44370	injection of substance into other organism during feeding on blood of other organism	P	The process of forcing a substance into the bloodstream of another organism, whilst feeding on blood of other organism. The substance may facilitate the feeding process, e.g. by preventing the blood from clotting.
44371	feeding from phloem of other organism	P	The behaviour of consuming phloem sap, usually by penetration of the phloem wall, for the purposes of nutrition.
44372	feeding from xylem of other organism	P	The behaviour of consuming xylem exudate from plant xylem tissue for the purposes of nutrition.
44373	cytokinin binding	F	Interacting selectively and non-covalently with a cytokinin, any of a class of adenine-derived compounds that can function in plants as growth regulators.
44374	sequence-specific DNA binding, bending	F	The activity of binding selectively and non-covalently to DNA in a sequence-specific manner and distorting the original structure of DNA, typically a straight helix, into a bend, or increasing the bend if the original structure was intrinsically bent due to its sequence.
44375	regulation of peroxisome size	P	Any process that modulates the volume of a peroxisome, a small, membrane-bounded organelle that uses dioxygen (O2) to oxidize organic molecules.
44376	RNA polymerase II complex import to nucleus	P	The directed movement of the DNA-directed RNA polymerase II core complex from the cytoplasm into the nucleus.
44377	RNA polymerase II core promoter proximal region sequence-specific DNA binding, bending	F	Interacting selectively and non-covalently with a sequence of DNA that is in cis with and relatively close to a core promoter for RNA polymerase II and distorting the original structure of DNA, typically a straight helix, into a bend, or increasing the bend if the original structure was intrinsically bent due to its sequence.
44378	non-sequence-specific DNA binding, bending	F	The activity of binding selectively and non-covalently to DNA in a sequence-independent manner and distorting the original structure of DNA, typically a straight helix, into a bend, or increasing the bend if the original structure was intrinsically bent due to its sequence.
44379	protein localization to actin cortical patch	P	A process in which a protein is transported to, or maintained in, an actin cortical patch.
44380	protein localization to cytoskeleton	P	A process in which a protein is transported to, or maintained in, a location within the cytoskeleton.
44381	glucose import in response to insulin stimulus	P	The directed movement of the hexose monosaccharide glucose into a cell as a result of an insulin stimulus.
44382	CLRC ubiquitin ligase complex localization to heterochromatin	P	The process by which a CLRC ubiquitin ligase complex is transported to, or maintained in, heterochromatin. CLRC ubiquitin ligase complex is an active cullin-dependent E3 ubiquitin ligase complex essential for heterochromatin assembly by RNAi and histone H3K9 methylation.
44383	host chromosome	C	A structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information, occurring within a host cell.
44384	host outer membrane	C	The external membrane of Gram-negative bacteria or certain organelles such as mitochondria and chloroplasts; freely permeable to most ions and metabolites, occurring in a host cell.
44385	integral to membrane of host cell	C	Penetrating at least one phospholipid bilayer of a membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer. When used to describe a protein, indicates that all or part of the peptide sequence is embedded in the membrane. Occurring in a host cell.
44386	integral to host endoplasmic reticulum membrane	C	Penetrating at least one phospholipid bilayer of an endoplasmic reticulum membrane. May also refer to the state of being buried in the bilayer with no exposure outside the bilayer. Occurring in a host cell.
44387	negative regulation of protein kinase activity by regulation of protein phosphorylation	P	The stopping, prevention, or reduction in frequency, rate or extent of protein kinase activity as a result of regulating the phosphorylation status of that protein kinase.
44388	small protein activating enzyme binding	F	Interacting selectively and non-covalently with a small protein activating enzyme, such as ubiquitin-activating enzyme.
44389	ubiquitin-like protein ligase binding	F	Interacting selectively and non-covalently with a ubiquitin-like protein ligase, such as ubiquitin-ligase.
44390	ubiquitin-like protein conjugating enzyme binding	F	Interacting selectively and non-covalently with a ubiquitin-like protein conjugating enzyme such as ubiquitin conjugating enzyme.
44391	ribosomal subunit	C	Either of the two subunits of a ribosome: the ribosomal large subunit or the ribosomal small subunit.
44392	peptidyl-lysine malonylation	P	The addition of a malonyl group (CO-CH2-CO) to peptidyl-lysine to form N6-malonyl-L-lysine.
44393	microspike	C	A dynamic, actin-rich projection extending from the surface of a migrating animal cell.
44394	protein malonylation	P	The modification of a protein amino acid by the addition of a malonyl (CO-CH2-CO) group.
44395	protein targeting to vacuolar membrane	P	The process of directing proteins towards the vacuolar membrane; usually uses signals contained within the protein.
44396	actin cortical patch organization	P	A process that is carried out at the cellular level and results in the assembly, arrangement of constituent parts, or disassembly of an actin cortical patch, a discrete actin-containing structure found at the plasma membrane in cells, at sites of endocytosis.
44397	actin cortical patch internalization	P	A process of actin cortical patch localization in which the patch moves from the cell surface to the inside of the cell.
44398	envenomation resulting in induction of edema in other organism	P	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the swelling of soft tissues of the bitten organism as a result of excess water accumulation.
44399	multi-species biofilm formation	P	A process in which planktonically growing microorganisms of different species grow at a liquid-air interface or on a solid substrate under the flow of a liquid and produce extracellular polymers that facilitate matrix formation, resulting in a change in the organisms' growth rate and gene transcription.
44400	multi-species biofilm formation on inanimate substrate	P	A process in which microorganisms of different species attach to and grow on an inanimate surface such as a rock or pipe and produce extracellular polymers that facilitate attachment and matrix formation, resulting in a change in the organisms' growth rate and gene transcription.
44401	multi-species biofilm formation in or on host organism	P	A process in which microorganisms of different species attach to and grow in or on a host species, and produce extracellular polymers that facilitate attachment and matrix formation, resulting in a change in the microorganisms' growth rate and gene transcription. The host is defined as the larger of the organisms involved in a symbiotic interaction.
44402	competition with other organism	P	Any process in which an organism within a multispecies community gains an advantage in growth or survival over another organism of a different species in that community.
44403	symbiosis, encompassing mutualism through parasitism	P	An interaction between two organisms living together in more or less intimate association. Microscopic symbionts are often referred to as endosymbionts. The various forms of symbiosis include parasitism, in which the association is disadvantageous or destructive to one of the organisms; mutualism, in which the association is advantageous, or often necessary to one or both and not harmful to either; and commensalism, in which one member of the association benefits while the other is not affected. However, mutualism, parasitism, and commensalism are often not discrete categories of interactions and should rather be perceived as a continuum of interaction ranging from parasitism to mutualism. In fact, the direction of a symbiotic interaction can change during the lifetime of the symbionts due to developmental changes as well as changes in the biotic/abiotic environment in which the interaction occurs.
44405	recognition of host	P	The set of specific processes that allow an organism to detect the presence of its host via physical or chemical signals. The host is defined as the larger of the organisms involved in a symbiotic interaction.
44406	adhesion of symbiont to host	P	The attachment of a symbiont to its host via adhesion molecules, general stickiness etc., either directly or indirectly. The host is defined as the larger of the organisms involved in a symbiotic interaction.
44407	single-species biofilm formation in or on host organism	P	A process in which microorganisms of the same species attach to and grow in or on a host species, and produce extracellular polymers that facilitate attachment and matrix formation, resulting in a change in the microorganisms' growth rate and gene transcription. The host is defined as the larger of the organisms involved in a symbiotic interaction.
44409	entry into host	P	Penetration by an organism into the body, tissues, or cells of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
44410	entry into host through natural portals	P	Penetration by an organism into its host organism via naturally occurring openings in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
44411	entry into host through host barriers	P	Penetration by an organism into its host organism via active breaching of the physical barriers of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
44413	avoidance of host defenses	P	Any process, either constitutive or induced, by which an organism evades, suppresses or tolerates the effects of its host organism's defense(s). Host defenses may be induced by the presence of the organism or may be preformed (e.g. physical barriers). The host is defined as the larger of the organisms involved in a symbiotic interaction.
44414	suppression of host defenses	P	Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of host defense(s) by active mechanisms that normally result in the shutting down of a host pathway. The host is defined as the larger of the organisms involved in a symbiotic interaction.
44415	evasion or tolerance of host defenses	P	Any process, either active or passive, by which an organism avoids or tolerates the effects of its host organism's defense(s). Host defenses may be induced by the presence of the organism or may be preformed (e.g. physical barriers). The host is defined as the larger of the organisms involved in a symbiotic interaction.
44416	induction by symbiont of host defense response	P	The activation by an organism of the defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
44417	translocation of molecules into host	P	The directed movement of a molecule(s) produced by an organism to a location inside its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
44418	translocation of DNA into host	P	The directed movement of DNA from an organism to a location inside its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
44419	interspecies interaction between organisms	P	Any process in which an organism has an effect on an organism of a different species.
44420	extracellular matrix component	C	Any constituent part of the extracellular matrix, the structure lying external to one or more cells, which provides structural support for cells or tissues; may be completely external to the cell (as in animals) or be part of the cell (as often seen in plants).
44421	extracellular region part	C	Any constituent part of the extracellular region, the space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers constituent parts of the host cell environment outside an intracellular parasite.
44422	organelle part	C	Any constituent part of an organelle, an organized structure of distinctive morphology and function. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton, but excludes the plasma membrane.
44423	virion part	C	Any constituent part of a virion, a complete fully infectious extracellular virus particle.
44424	intracellular part	C	Any constituent part of the living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.
44425	membrane part	C	Any constituent part of a membrane, a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.
44426	cell wall part	C	Any constituent part of the cell wall, the rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal, and most prokaryotic cells, maintaining their shape and protecting them from osmotic lysis.
44427	chromosomal part	C	Any constituent part of a chromosome, a structure composed of a very long molecule of DNA and associated proteins (e.g. histones) that carries hereditary information.
44428	nuclear part	C	Any constituent part of the nucleus, a membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated.
44429	mitochondrial part	C	Any constituent part of a mitochondrion, a semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
44430	cytoskeletal part	C	Any constituent part of the cytoskeleton, a cellular scaffolding or skeleton that maintains cell shape, enables some cell motion (using structures such as flagella and cilia), and plays important roles in both intra-cellular transport (e.g. the movement of vesicles and organelles) and cellular division. Includes constituent parts of intermediate filaments, microfilaments, microtubules, and the microtrabecular lattice.
44431	Golgi apparatus part	C	Any constituent part of the Golgi apparatus, a compound membranous cytoplasmic organelle of eukaryotic cells, consisting of flattened, ribosome-free vesicles arranged in a more or less regular stack.
44432	endoplasmic reticulum part	C	Any constituent part of the endoplasmic reticulum, the irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae.
44433	cytoplasmic vesicle part	C	Any constituent part of cytoplasmic vesicle, a vesicle formed of membrane or protein, found in the cytoplasm of a cell.
44434	chloroplast part	C	Any constituent part of a chloroplast, a chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma.
44435	plastid part	C	Any constituent part of a plastid, a member of a family of organelles found in the cytoplasm of plants and some protists, which are membrane-bounded and contain DNA. Plant plastids develop from a common type, the proplastid.
44436	thylakoid part	C	Any constituent part of a thylakoid, a sac-like vesicle that bears the photosynthetic pigments in photosynthetic organisms.
44437	vacuolar part	C	Any constituent part of a vacuole, a closed structure, found only in eukaryotic cells, that is completely surrounded by unit membrane and contains liquid material.
44438	microbody part	C	Any constituent part of a microbody, a cytoplasmic organelle, spherical or oval in shape, that is bounded by a single membrane and contains oxidative enzymes, especially those utilizing hydrogen peroxide (H2O2).
44439	peroxisomal part	C	Any constituent part of a peroxisome, a small, membrane-bounded organelle that uses dioxygen (O2) to oxidize organic molecules; contains some enzymes that produce and others that degrade hydrogen peroxide (H2O2).
44440	endosomal part	C	Any constituent part of an endosome, a membrane-bounded organelle to which materials ingested by endocytosis are delivered.
44441	ciliary part	C	Any constituent part of a cilium, a specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic (plasma) membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole.
44443	pilus part	C	Any constituent part of a pilus, a proteinaceous hair-like appendage on the surface of bacteria ranging from 2-8 nm in diameter.
44444	cytoplasmic part	C	Any constituent part of the cytoplasm, all of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
44445	cytosolic part	C	Any constituent part of cytosol, that part of the cytoplasm that does not contain membranous or particulate subcellular components.
44446	intracellular organelle part	C	A constituent part of an intracellular organelle, an organized structure of distinctive morphology and function, occurring within the cell. Includes constituent parts of the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton but excludes the plasma membrane.
44447	axoneme part	C	Any constituent part of an axoneme, the bundle of microtubules and associated proteins that forms the core of cilia (also called flagella) in eukaryotic cells and is responsible for their movements.
44448	cell cortex part	C	Any constituent part of the cell cortex, the region of a cell that lies just beneath the plasma membrane and often, but not always, contains a network of actin filaments and associated proteins.
44449	contractile fiber part	C	Any constituent part of a contractile fiber, a fiber composed of actin, myosin, and associated proteins, found in cells of smooth or striated muscle.
44450	microtubule organizing center part	C	Any constituent part of a microtubule organizing center, a region in a eukaryotic cell, such as a centrosome or basal body, from which microtubules grow.
44451	nucleoplasm part	C	Any constituent part of the nucleoplasm, that part of the nuclear content other than the chromosomes or the nucleolus.
44452	nucleolar part	C	Any constituent part of a nucleolus, a small, dense body one or more of which are present in the nucleus of eukaryotic cells. It is rich in RNA and protein, is not bounded by a limiting membrane, and is not seen during mitosis.
44453	nuclear membrane part	C	Any constituent part of the nuclear membrane, the envelope that surrounds the nucleus of eukaryotic cells.
44454	nuclear chromosome part	C	Any constituent part of a nuclear chromosome, a chromosome that encodes the nuclear genome and is found in the nucleus of a eukaryotic cell during the cell cycle phases when the nucleus is intact.
44455	mitochondrial membrane part	C	Any constituent part of a mitochondrial membrane, either of the lipid bilayers that surround the mitochondrion and form the mitochondrial envelope.
44456	synapse part	C	Any constituent part of a synapse, the junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell.
44457	cell septum part	C	Any constituent part of a cell septum, a structure composed of peptidoglycan and often chitin in addition to other materials. It usually forms perpendicular to the long axis of a cell or hypha and grows centripetally from the cell wall to the center of the cell and often functions in the compartmentalization of a cell into two daughter cells.
44458	motile cilium assembly	P	The aggregation, arrangement and bonding together of a set of components to form a motile cilium.
44459	plasma membrane part	C	Any constituent part of the plasma membrane, the membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
44461	bacterial-type flagellum part	C	Any constituent part of flagellum, a 20 nm diameter filament composed of subunits of flagellin driven passively at its base by a motor powered by the transmembrane proton potential. Examples of this component are found in bacterial species.
44462	external encapsulating structure part	C	Any constituent part of an external encapsulating structure, a structure that lies outside the plasma membrane and surrounds the entire cell. This does not include the periplasmic space but does include the outer membrane (of gram negative bacteria) or cell wall (of yeast or Gram positive bacteria).
44463	cell projection part	C	Any constituent part of a cell projection, a prolongation or process extending from a cell, e.g. a flagellum or axon.
44464	cell part	C	Any constituent part of a cell, the basic structural and functional unit of all organisms.
44465	modulation of sensory perception of pain in other organism	P	A process that modulates the frequency, rate or extent of the sensory perception of pain, the series of events required for an organism to receive a painful stimulus, convert it to a molecular signal, and recognize and characterize the signal, in a different organism.
44466	glutaryl-CoA hydrolase activity	F	Catalysis of the reaction: glutaryl-CoA + H2O = CoA + glutarate.
44467	glial cell-derived neurotrophic factor secretion	P	The regulated release of glial cell line-derived neurotrophic factor from a cell. Glial cell-derived neurotrophic factor (GDNF) is a small protein that potently promotes the survival of many types of neurons, notably dopaminergic and motor neurons.
44468	envenomation resulting in modulation of blood coagulation in other organism	P	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the modulation of the frequency, rate or extent of blood coagulation in the bitten organism.
44469	envenomation resulting in positive regulation of blood coagulation in other organism	P	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant activation, maintenance or an increase in the frequency, rate or extent of blood coagulation in the bitten organism.
44470	envenomation resulting in negative regulation of blood coagulation in other organism	P	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant stopping, prevention or reduction in the frequency, rate or extent of blood coagulation in the bitten organism.
44471	envenomation resulting in pore formation in membrane of other organism	P	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the aggregation, arrangement and bonding together of a set of components to form a pore complex in a membrane of the bitten organism.
44472	envenomation resulting in modulation of calcium channel activity in other organism	P	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with a resultant change in the activity of a calcium channel in the bitten organism.
44473	envenomation resulting in negative regulation of calcium channel activity in other organism	P	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant stopping, prevention or reduction of the activity of a calcium channel in the bitten organism.
44474	envenomation resulting in negative regulation of voltage-gated calcium channel activity in other organism	P	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant stopping, prevention or reduction of the activity of a voltage-gated calcium channel in the bitten organism.
44475	envenomation resulting in negative regulation of high voltage-gated calcium channel activity in other organism	P	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant stopping, prevention or reduction of the activity of a high voltage-gated calcium channel in the bitten organism.
44476	envenomation resulting in negative regulation of low voltage-gated calcium channel activity in other organism	P	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant stopping, prevention or reduction of the activity of a low voltage-gated calcium channel in the bitten organism.
44477	envenomation resulting in negative regulation of platelet aggregation in other organism	P	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant stopping, prevention or reduction in the frequency, rate or extent of platelet aggregation in the bitten organism.
44478	envenomation resulting in positive regulation of platelet aggregation in other organism	P	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant activation, maintenance or an increase in the frequency, rate or extent of platelet aggregation in the bitten organism.
44479	envenomation resulting in modulation of mast cell degranulation in other organism	P	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant modulation of blood mast cell degranulation in the bitten organism.
44480	envenomation resulting in positive regulation of mast cell degranulation in other organism	P	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant positive regulation of blood mast cell degranulation in the bitten organism.
44481	envenomation resulting in proteolysis in other organism	P	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant hydrolysis of proteins in of the bitten organism.
44482	envenomation resulting in blood vessel extracellular matrix damage, causing hemorrhagic damage in other organism	P	A process that begins with venom being forced into an organism by the bite or sting of another organism which causes damage to the extracellular matrix of the blood vessels of the bitten organism, ultimately resulting in hemorrhage in the bitten organism.
44483	envenomation resulting in impairment of hemostasis in other organism	P	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the inhibition of the process of hemostasis - the stopping of bleeding or the arrest of the circulation to an organ or part - in the bitten organism.
44484	envenomation resulting in fibrinolysis in other organism	P	The process which begins with venom being forced into an organism by the bite or sting of another organism, and ends with fibrinolysis, a process that solubilizes fibrin, chiefly by the proteolytic action of plasmin, in the bloodstream of the bitten/stung organism.
44485	envenomation resulting in fibrinogenolysis in other organism	P	The process which begins with venom being forced into an organism by the bite or sting of another organism, and ends with fibrinogenolysis, a process that degrades fibrinogen at a variety of Arg-Lys bonds, thus impairing fibrinogen clotting in the bloodstream of the bitten/stung organism.
44486	modulation of transmission of nerve impulse in other organism	P	The process in which an organism effects a change in the transmission of a nerve impulse in another organism.
44487	envenomation resulting in modulation of transmission of nerve impulse in other organism	P	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant modulation of the transmission of nerve impulses in the bitten organism.
44488	modulation of voltage-gated sodium channel activity in other organism	P	Any process in which an organism effects a change in the frequency, rate or extent of the activity of a voltage-gated sodium channel in another organism.
44489	negative regulation of voltage-gated sodium channel activity in other organism	P	Any process in which an organism stops, prevents or reduces the frequency, rate or extent of the activity of a voltage-gated sodium channel in another organism.
44490	positive regulation of voltage-gated sodium channel activity in other organism	P	Any process that activates or increases the frequency, rate or extent of the activity of a voltage-gated sodium channel in another organism.
44491	positive regulation of molecular function in other organism	P	Any process that activates or increases the frequency, rate or extent of the function of proteins in a second organism.
44492	envenomation resulting in modulation of voltage-gated sodium channel activity in other organism	P	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with a resultant change in the activity of a voltage-gated sodium channel in the bitten organism.
44493	envenomation resulting in negative regulation of voltage-gated sodium channel activity in other organism	P	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant stopping, prevention or reduction of the activity of a voltage-gated sodium channel in the bitten organism.
44494	envenomation resulting in positive regulation of voltage-gated sodium channel activity in other organism	P	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant activation or increase in the activity of the activity of a voltage-gated sodium channel in the bitten organism.
44495	modulation of blood pressure in other organism	P	A process by which one organism modulates the force with which blood travels through the circulatory system of another organism.
44496	negative regulation of blood pressure in other organism	P	A process by which one organism decreases the force with which blood travels through the circulatory system of another organism.
44497	positive regulation of blood pressure in other organism	P	A process by which one organism increases the force with which blood travels through the circulatory system of another organism.
44498	envenomation resulting in modulation of blood pressure in other organism	P	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant modulation of the force with which blood travels through the circulatory system of the bitten/stung organism.
44499	envenomation resulting in positive regulation of blood pressure in other organism	P	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant increase of the force with which blood travels through the circulatory system of the bitten/stung organism.
44500	envenomation resulting in negative regulation of blood pressure in other organism	P	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant decrease of the force with which blood travels through the circulatory system of the bitten/stung organism.
44501	modulation of signal transduction in other organism	P	The process in which an organism effects a change in a signal transduction process - a cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell - in a second organism.
44502	positive regulation of signal transduction in other organism	P	A process in which an organism activates, maintains or increases the frequency, rate or extent of a signal transduction process - a cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell - in a second organism.
44503	modulation of G-protein coupled receptor activity in other organism	P	The process in which an organism effects a change in the activity of a G-protein coupled receptor in a second organism.
44504	modulation of receptor activity in other organism	P	The process in which an organism effects a change in the activity of a receptor in a second organism.
44505	positive regulation of G-protein coupled receptor activity in other organism	P	A process that activates or increases the frequency, rate or extent of the activity of a G-protein coupled receptor in a second organism.
44506	modulation of glucagon-like peptide receptor 1 activity in other organism	P	The process in which an organism effects a change in the activity of a glucagon-like peptide receptor 1 in a second organism.
44507	positive regulation of receptor activity in other organism	P	A process that activates or increases the frequency, rate or extent of the activity of a receptor in a second organism.
44508	glucagon-like peptide 1 receptor activity	F	Combining with glucagon-like peptide 1 and transmitting the signal across the membrane by activating an associated G-protein.
44509	envenomation resulting in modulation of signal transduction in other organism	P	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant modulation of signal transduction in the bitten organism.
44510	envenomation resulting in positive regulation of signal transduction in other organism	P	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant positive regulation of signal transduction in the bitten organism.
44511	envenomation resulting in modulation of receptor activity in other organism	P	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant modulation of receptor activity in of the bitten organism.
44512	envenomation resulting in modulation of glucagon-like peptide receptor 1 activity in other organism	P	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant modulation of glucagon-like peptide receptor 1 activity in of the bitten organism.
44513	envenomation resulting in modulation of G-protein coupled receptor activity in other organism	P	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant modulation of G-protein coupled receptor activity in of the bitten organism.
44514	envenomation resulting in positive regulation of G-protein coupled receptor activity in other organism	P	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant positive regulation of G-protein coupled receptor activity in of the bitten organism.
44515	envenomation resulting in positive regulation of glucagon-like peptide receptor 1 activity in other organism	P	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant positive regulation of glucagon-like peptide receptor 1 activity in of the bitten organism.
44516	positive regulation of glucagon-like peptide receptor 1 activity in other organism	P	A process that activates or increases the frequency, rate or extent of the activity of a glucagon-like peptide receptor 1 in a second organism.
44517	modulation of vasoactive intestinal polypeptide receptor activity in other organism	P	The process in which an organism effects a change in the activity of a vasoactive intestinal polypeptide receptor in a second organism.
44518	positive regulation of vasoactive intestinal polypeptide receptor activity in other organism	P	A process that activates or increases the frequency, rate or extent of the activity of a vasoactive intestinal polypeptide receptor in a second organism.
44519	envenomation resulting in modulation of vasoactive intestinal polypeptide receptor activity in other organism	P	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant modulation of the activity of a vasoactive intestinal polypeptide receptor in the bitten organism.
44520	envenomation resulting in positive regulation of vasoactive intestinal polypeptide receptor activity in other organism	P	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant positive regulation of the activity of a vasoactive intestinal polypeptide receptor in the bitten organism.
44521	envenomation resulting in muscle damage in other organism	P	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with resultant muscle damage in the bitten organism.
44522	envenomation resulting in myocyte killing in other organism	P	A process that begins with venom being forced into an organism by the bite or sting of another organism, killing heart myocytes and ultimately resulting in muscle damage in the bitten organism.
44523	envenomation resulting in damage of muscle extracellular matrix in other organism	P	A process that begins with venom being forced into an organism by the bite or sting of another organism, damaging the extracellular matrix of muscle cells and ultimately resulting in muscle necrosis in the bitten organism.
44524	protein sulfhydration	P	The modification of a protein amino acid by the addition of sulfur.
44525	peptidyl-cystine sulfhydration	P	The modification of a peptidyl-cystine residue in a protein by the addition of sulfur, to form peptidyl-cysteine persulfide.
44526	formation of peptidyl-cystine persulfide by sulphur transfer from free cysteine	P	The modification of a peptidyl-cystine residue in a protein by the transfer of a sulfur atom from a free cysteine (in the process converting the free cysteine to alanine) to the peptidyl-cysteine to form peptidyl-cysteine persulfide.
44527	formation of peptidyl-cystine persulfide by sulphur transfer from H2S	P	The modification of a peptidyl-cystine residue in a protein by the direct addition of H2S, followed by the removal of 2 protons to form peptidyl-cysteine persulfide.
44528	regulation of mitochondrial mRNA stability	P	Any process that modulates the propensity of mitochondrial mRNA molecules to degradation. Includes processes that both stabilize and destabilize mitochondrial mRNAs.
44529	regulation of mitochondrial rRNA stability	P	Any process that modulates the propensity of mitochondrial rRNA molecules to degradation. Includes processes that both stabilize and destabilize mitochondrial rRNAs.
44530	supraspliceosomal complex	C	Multicomponent complex of RNA and proteins that is composed of four active spliceosomes, termed native spliceosomes, connected to each other by the pre-mRNA. The supraspliceosome is the nuclear machine where the pre-mRNA processing takes place, like the 5'-end capping, 3'-end cleavage, splicing and editing.
44531	modulation of programmed cell death in other organism	P	A process in which an organism modulates the frequency, rate or extent of programmed cell death in a second organism.
44532	modulation of apoptotic process in other organism	P	A process in which an organism modulates the frequency, rate or extent of apoptosis in a second organism.
44533	positive regulation of apoptotic process in other organism	P	Any process in which an organism activates, maintains or increases the frequency, rate or extent of programmed cell death by apoptosis in a second organism.
44534	envenomation resulting in modulation of apoptotic process in other organism	P	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant modulation of apoptosis in the bitten organism.
44535	very-long-chain fatty acyl-CoA oxidase activity	F	Catalysis of the reaction: very-long-chain fatty acyl-CoA (C22 - C24) + O2 = trans-2,3-dehydroacyl-CoA + hydrogen peroxide.
44536	envenomation resulting in depletion of circulating fibrinogen in other organism	P	The process which begins with venom being forced into an organism by the bite or sting of another organism, and ends with a reduction in the quantity of fibrinogen found in the bloodstream of the bitten/stung organism.
44537	regulation of circulating fibrinogen levels	P	Any process that modulates the quantity of fibrinogen circulating in the bloodstream.
44538	host cell periphery	C	The part of a cell encompassing the cell cortex, the plasma membrane, and any external encapsulating structures of a host cell.
44539	long-chain fatty acid import	P	The directed movement of long-chain fatty acids into a cell or organelle. A long-chain fatty acid is a fatty acid with a chain length between C13 and C22.
44540	L-cystine L-cysteine-lyase (deaminating)	F	Catalysis of the reaction: L-cystine + H2O <=> pyruvate + NH3 + thiocysteine. Thiocysteine is also known as cysteine persulfide.
44541	zymogen activation in other organism	P	The chemical reactions and pathways performed by an organism resulting in the proteolytic processing of an inactive enzyme to an active form in another organism.
44542	plasminogen activation in other organism	P	The chemical reactions and pathways performed by an organism resulting in the processing of inactive plasminogen to active plasmin in another organism.
44543	envenomation resulting in zymogen activation in other organism	P	The process which begins with venom being forced into an organism by the bite or sting of another organism, and ends with the proteolytic processing of an inactive enzyme to an active form.
44544	envenomation resulting in plasminogen activation in other organism	P	The process which begins with venom being forced into an organism by the bite or sting of another organism, and ends with the activation of plasminogen into plasmin in the bitten organism. This process includes cleavage at an internal Arg-Val site to form an N-terminal A-chain and C-terminal B-chain held together by a disulfide bond, and can include further proteolytic cleavage events to remove the preactivation peptide.
44545	NSL complex	C	A histone acetyltransferase complex that catalyzes the acetylation of a histone H4 lysine residues at several positions. In human, it contains the catalytic subunit MOF, NSL1/KIAA1267, NSL2/KANSL2, NSL3/KANSL3, MCRS1, PHF20, OGT1, WDR5 and HCF1.
44546	NLRP3 inflammasome complex assembly	P	The aggregation, arrangement and bonding together of a set of components to form the NLRP3 inflammasome complex, occurring at the level of an individual cell.
44547	DNA topoisomerase binding	F	Interacting selectively and non-covalently with a DNA topoisomerase.
44548	S100 protein binding	F	Interacting selectively and non-covalently with a S100 protein. S100 is a small calcium and zinc binding protein produced in astrocytes that is implicated in Alzheimer's disease, Down Syndrome and ALS.
44549	GTP cyclohydrolase binding	F	Interacting selectively and non-covalently with a GTP cyclohydrolase.
44550	secondary metabolite biosynthetic process	P	The chemical reactions and pathways resulting in the formation of secondary metabolites, the compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon.
44551	envenomation resulting in modulation of vasodilation in other organism	P	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with resultant modulation of vasodilation of blood vessels, usually causing a reduction in blood pressure, in the bitten/stung organism.
44552	modulation of vasodilation in other organism	P	A process by which an organism causes vasodilation of blood vessels, usually causing a reduction in blood pressure, in another organism.
44553	modulation of biological quality in other organism	P	Any process that modulates the frequency, rate or extent of a biological quality in another organism. A biological quality is a measurable attribute of an organism or part of an organism, such as size, mass, shape, color, etc.
44554	modulation of heart rate in other organism	P	Any process that modulates the frequency or rate of heart contraction of another organism.
44555	negative regulation of heart rate in other organism	P	Any process that stops, prevents or reduces the frequency of heart contraction of another organism.
44556	envenomation resulting in negative regulation of heart rate of other organism	P	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the negative regulation of the heart rate of the bitten/stung organism.
44557	relaxation of smooth muscle	P	A process in which the extent of smooth muscle contraction is reduced. Smooth muscle differs from striated muscle in the much higher actin/myosin ratio, the absence of conspicuous sarcomeres and the ability to contract to a much smaller fraction of its resting length.
44558	uterine smooth muscle relaxation	P	A process in which the extent of smooth muscle contraction is reduced in the uterus.
44559	envenomation resulting in modulation of voltage-gated potassium channel activity in other organism	P	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with a resultant change in the activity of a voltage-gated potassium channel in the bitten/stung organism.
44560	envenomation resulting in modulation of ion channel activity in other organism	P	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with a resultant change in the activity of an ion channel in the bitten organism.
44561	modulation of ion channel activity in other organism	P	Any process in which an organism effects a change in the frequency, rate or extent of the activity of an ion channel in another organism.
44562	envenomation resulting in negative regulation of voltage-gated potassium channel activity in other organism	P	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with a resultant negative regulation of the activity of a voltage-gated potassium channel in the bitten/stung organism.
44563	envenomation resulting in slowing of activation kinetics of voltage-gated potassium channel in other organism	P	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with a resultant slowing of the activation kinetics of the activity of a voltage-gated potassium channel in the bitten/stung organism.
44564	envenomation resulting in occlusion of the pore of voltage-gated potassium channel in other organism	P	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with a resultant blocking of a voltage-gated potassium channel, inhibiting the pore's activity, in the bitten/stung organism.
44565	dendritic cell proliferation	P	The expansion of a dendritic cell population by cell division. A dendritic cell is a cell of hematopoietic origin, typically resident in particular tissues, specialized in the uptake, processing, and transport of antigens to lymph nodes for the purpose of stimulating an immune response via T cell activation.
44566	chondrocyte activation	P	A change in the morphology or behavior of a chondrocyte resulting from exposure to an activating factor such as a cellular or soluble ligand. A chondrocyte is a polymorphic cell that forms cartilage.
44567	primary cell wall cellulose synthase complex	C	A large, multimeric protein complex which catalyzes the biosynthesis of cellulose for the plant primary cell wall. In Arabidopsis, contains the essential component proteins CESA1 and -3, and a CESA6-related protein.
44568	secondary cell wall cellulose synthase complex	C	A large, multimeric protein complex which catalyzes the biosynthesis of cellulose for the plant secondary cell wall. In Arabidopsis, contains the essential component proteins CESA8, CESA7, and CESA4.
44569	[Ni-Fe] hydrogenase complex	C	A microbial enzyme complex which contains nickel and iron in its active site. In Acetomicrobium flavidum it is an alpha 2 beta 2 tetramer.
44570	starch utilization system complex	C	A bacterial cell envelope-associated multiprotein system, which binds and degrades starch.
44571	[2Fe-2S] cluster assembly	P	The incorporation of two iron atoms and two sulfur atoms into an iron-sulfur cluster.
44572	[4Fe-4S] cluster assembly	P	The incorporation of four iron atoms and four sulfur atoms into an iron-sulfur cluster.
44573	nitrogenase P cluster assembly	P	The biochemical reactions and pathways resulting in the formation of a P-cluster of a nitrogenase, a high-nuclearity, Fe/S-only cluster that can be viewed as two [4Fe-4S] sub-clusters sharing a gamma-6-sulfide.
44574	starch utilization system complex assembly	P	The aggregation, arrangement and bonding together of the starch utilization system complex, a complex of cell envelope-associated proteins that degrades glycan.
44575	cellulosome assembly	P	The assembly of a cellulosome, a macromolecular multi-enzyme complex in bacteria that facilitates the breakdown of cellulase, hemicellulase and pectin in the plant cell wall.
44576	pentose catabolic process to ethanol	P	The anaerobic chemical reactions and pathways resulting in the breakdown of a pentose, any monosaccharide with a chain of five carbons, where one of the resulting products is ethanol.
44577	xylose catabolic process to ethanol	P	The anaerobic chemical reactions and pathways resulting in the breakdown of xylose, an aldopentose, where one of the resulting products is ethanol.
44578	butyryl-CoA biosynthetic process	P	The chemical reactions and pathway resulting in the formation of butyryl-CoA.
44579	butyryl-CoA biosynthetic process from acetyl-CoA	P	The chemical reactions and pathway resulting in the formation of butyryl-CoA, starting from acetyl-CoA.
44580	butyryl-CoA catabolic process	P	The chemical reactions a resulting in the resulting in the breakdown of butyryl-CoA.
44581	butyryl-CoA catabolic process to butyrate	P	The chemical reactions a resulting in the resulting in the breakdown of butyryl-CoA to form butyrate.
44582	butyryl-CoA catabolic process to butanol	P	The chemical reactions a resulting in the resulting in the breakdown of butyryl-CoA to form butanol.
44583	cellotriose binding	F	Interacting selectively and non-covalently with cellotriose.
44584	cellodextrin binding	F	Interacting selectively and non-covalently with cellodextrin, a glucose polymer of 2 or more glucose monomers.
44585	cellobiose binding	F	Interacting selectively and non-covalently with cellobiose, a disaccharide that represents the basic repeating unit of cellulose.
44586	cellotetraose binding	F	Interacting selectively and non-covalently with cellotetraose, an oligosaccharide consisting of four glucose residues resulting from hydrolysis of cellulose.
44587	cellopentaose binding	F	Interacting selectively and non-covalently with cellopentaose, an oligosaccharide consisting of four glucose residues resulting from hydrolysis of cellulose.
44588	laminaribiose binding	F	Interacting selectively and non-covalently with laminaribiose, a disaccharide.
44589	pectin binding	F	Interacting selectively and non-covalently with pectin.
44590	iron-sulfur-molybdenum cofactor binding	F	Interacting selectively and non-covalently with iron molybdenum cofactor, the cofactor located at the active site of the molybdenum nitrogenase.
44591	response to amylopectin	P	A process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of amylopectin stimulus.
44592	response to pullulan	P	A process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of pullulan stimulus.
44593	iron-sulfur-molybdenum cofactor assembly	P	The chemical reactions and pathways resulting in the formation of iron-sulfur-molybdenum cofactor, the cofactor located at the active site of the molybdenum nitrogenase.
44594	17-beta-hydroxysteroid dehydrogenase (NAD+) activity	F	Catalysis of the reaction: a 17-beta-hydroxysteroid + NAD+ = a 17-oxosteroid + NADH + H+.
44595	decaprenyldihydroxybenzoate methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + 3-decaprenyl-4,5-dihydroxybenzoate = S-adenosyl-L-homocysteine + 3-decaprenyl-4-hydroxy-5-methoxybenzoate.
44596	3-demethylubiquinone-10 3-O-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + 3-demethylubiquinone-10 = S-adenosyl-L-homocysteine + ubiquinone-10.
44597	daunorubicin metabolic process	P	The chemical reactions and pathways involving daunorubicin, a chemotherapeutic of the anthracycline family that is given as a treatment for some types of cancer.
44598	doxorubicin metabolic process	P	The chemical reactions and pathways involving doxorubicin, an anthracycline antibiotic, used in cancer chemotherapy.
44599	AP-5 adaptor complex	C	An AP-type membrane coat adaptor complex that in humans consists of beta5, zeta, mu5 and sigma5 subunits and is found associated with membranes in the endosomes; it is not clear whether AP-5 forms clathrin coats in vivo.
44600	protein guanylyltransferase activity	F	Catalysis of the reaction: GTP + protein = diphosphate + guanylyl-protein; mediates the addition of an guanylyl (guanosine 5'-monophosphate; GMP group) to specific residues of target proteins.
44601	protein denucleotidylation	P	The removal of a nucleotide from a protein amino acid.
44602	protein deadenylylation	P	The removal of an adenylyl group (adenosine 5'-monophosphate; AMP) from a protein amino acid.
44603	protein adenylylhydrolase activity	F	Catalysis of the reaction: adenylyl-protein+ H2O = adenylate + protein; mediates the removal of an adenylyl (adenosine 5'-monophosphate; AMP group) from specific residues of target proteins.
44604	phytochelatin transmembrane transporter ATPase activity	F	Catalysis of the reaction: ATP + H2O + phytochelatin (in) = ADP + phosphate + phytochelatin (out).
44605	phosphocholine transferase activity	F	Catalysis of the reaction: CDP-choline + protein-serine = CMP + protein-serine-choline phosphate.
44606	phosphocholine hydrolase activity	F	Catalysis of the reaction: protein-serine-choline phosphate + H2O = protein-serine + choline phosphate.
44607	disruption by symbiont of host endothelial cells	P	Any process in which an organism has a negative effect on the functioning of the host's endothelial cells.
44608	peptidyl-L-threonine methyl ester biosynthetic process from peptidyl-threonine	P	The modification of a C-terminal peptidyl-threonine to form peptidyl-L-threonine methyl ester.
44609	DBIRD complex	C	A protein complex that associates with mRNP particles and RNA polymerase II and is proposed to integrate transcript elongation with the regulation of alternative splicing. In humans it is composed of the proteins KIAA1967/DBC1 and ZNF326/ZIRD.
44610	FMN transmembrane transporter activity	F	Enables the directed movement of flavine mononucleotide (FMN) into, out of or within a cell, or between cells.
44611	nuclear pore inner ring	C	A subcomplex of the nuclear pore complex (NPC) that forms the inner rings of the core scaffold, a lattice-like structure that gives the NPC its shape and strength. In S. cerevisiae, the two inner rings are each composed of Nup192p, Nup188p, Nup170p and Nup157p. In vertebrates, the two inner rings are each composed of Nup205, Nup188 and Nup155. Components are arranged in 8-fold symmetrical 'spokes' around the central transport channel. A single 'spoke', can be isolated and is sometimes referred to as the Nup170 complex.
44612	nuclear pore linkers	C	A substructure of the nuclear pore complex (NPC) that serves to connect members of the central transport channel (composed of FG-nucleoporins) to the core scaffold (composed of the inner and outer NPC rings). In S. cerevisiae, the linkers are Nic96p and Nup82p. In vertebrates, they are Nup93 and Nup88. Components are arranged in 8-fold symmetrical 'spokes' around the central transport channel. Both linkers can be isolated in association with specific FG-nucleoporins, complexes that are sometimes referred to as the Nic96 complex (Nic96p-Nsp1p-Nup49p-Nup57p) and the Nup82 complex (Nup82p-Nup116p-Nup159p-Gle2p).
44613	nuclear pore central transport channel	C	The central substructure of the nuclear pore complex (NPC), through which nucleocytoplasmic transport of RNAs, proteins and small molecules occurs. The central transport channel is filled with FG-nucleoporins, which form a selective barrier and provide a series of binding sites for transporter proteins. Characterized S. cerevisiae FG-nucleoporins include Nup159p, Nup145Np, Nup116p, Nup100p, Nsp1p, Nup57p, Nup49p, Nup42p, Nup53p, Nup59p/Asm4p, Nup60p and Nup1. Characterized vertebrate FG-nucleoporins include Nup214, Nup98, Nup62, Nup54, Nup58/45, NLP1, and Nup153.
44614	nuclear pore cytoplasmic filaments	C	Filamentous extensions on cytoplasmic face of the nuclear pore complex (NPC). In S. cerevisiae, Nup159p, Nup82p, and Nup42p contribute to the cytoplasmic filaments. In vertebrates, Nup358 is a major component.
44615	nuclear pore nuclear basket	C	A filamentous, cage-like assembly on the nuclear face of the nuclear pore complex (NPC). In S. cerevisiae, Mlp1p and Mlp2p are two major components of the NPC nuclear basket. In vertebrates, Tpr is a major component.
44616	modulation of relaxation of muscle in other organism	P	The process in which an organism effects a change in the relaxation of muscle in a second organism.
44617	modulation of relaxation of smooth muscle in other organism	P	The process in which an organism effects a change in the relaxation of smooth muscle in a second organism.
44618	modulation of relaxation of uterine smooth muscle in other organism	P	The process in which an organism effects a change in the relaxation of smooth muscle in the uterus of a second organism.
44619	positive regulation of relaxation of uterine smooth muscle in other organism	P	The process in which an organism increases the extent of relaxation of smooth muscle in the uterus of a second organism.
44620	ACP phosphopantetheine attachment site binding	F	Interacting selectively and non-covalently with the attachment site of the phosphopantetheine prosthetic group of an acyl carrier protein (ACP).
44621	modulation of cell migration in other organism	P	The process in which an organism effects a change in the process of cell migration in a second organism.
44622	negative regulation of cell migration in other organism	P	Any process that stops, prevents, or reduces the frequency, rate or extent of cell migration in a second organism.
44623	positive regulation of cell migration in other organism	P	Any process that activates or increases the frequency, rate or extent of cell migration in a second organism.
44624	envenomation resulting in modulation of cell migration in other organism	P	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the modulation of cell migration in the bitten organism.
44625	envenomation resulting in negative regulation of cell migration in other organism	P	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the negative regulation of cell migration in the bitten organism.
44626	envenomation resulting in positive regulation of cell migration in other organism	P	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the positive regulation of cell migration in the bitten organism.
44627	modulation of complement activation, classical pathway in other organism	P	A process that modulates the frequency, rate or extent of the classical pathway of complement activation, in a different organism.
44628	positive regulation of complement activation, classical pathway in other organism	P	Any process that activates or increases the frequency, rate or extent of complement activation by the classical pathway, in a different organism.
44629	negative regulation of complement activation, classical pathway in other organism	P	Any process that stops, prevents, or reduces the frequency, rate or extent of complement activation by the classical pathway, in a different organism.
44630	modulation of complement activation, lectin pathway in other organism	P	A process that modulates the frequency, rate or extent of the lectin pathway of complement activation, in a different organism.
44631	positive regulation of complement activation, lectin pathway in other organism	P	Any process that activates or increases the frequency, rate or extent of complement activation by the lectin pathway, in a different organism.
44632	negative regulation of complement activation, lectin pathway in other organism	P	Any process that stops, prevents, or reduces the rate of complement activation by the lectin pathway, in a different organism.
44633	modulation of complement activation, alternative pathway in other organism	P	A process that modulates the frequency, rate or extent of complement activation, via the alternative pathway, in a different organism.
44634	negative regulation of complement activation, alternative pathway in other organism	P	Any process that stops, prevents, or reduces the frequency, rate or extent of complement activation by the alternative pathway, in a different organism.
44635	positive regulation of complement activation, alternative pathway in other organism	P	Any process that activates or increases the frequency, rate or extent of complement activation by the alternative pathway, in a different organism.
44636	envenomation resulting in modulation of complement activation, classical pathway in other organism	P	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the regulation of complement activation via the classical pathway of the bitten/stung organism.
44637	envenomation resulting in negative regulation of complement activation, classical pathway in other organism	P	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the negative regulation of complement activation via the classical pathway of the bitten/stung organism.
44638	envenomation resulting in positive regulation of complement activation, classical pathway in other organism	P	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the positive regulation of complement activation via the classical pathway of the bitten/stung organism.
44639	envenomation resulting in modulation of complement activation, lectin pathway in other organism	P	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant modulation of complement activation via the lectin pathway in the bitten/stung organism.
44640	envenomation resulting in negative regulation of complement activation, lectin pathway in other organism	P	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant negative regulation of complement activation via the lectin pathway in the bitten/stung organism.
44641	envenomation resulting in positive regulation of complement activation, lectin pathway in other organism	P	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant positive regulation of complement activation via the lectin pathway in the bitten/stung organism.
44642	envenomation resulting in modulation of complement activation, alternative pathway in other organism	P	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant modulation of complement activation via the alternative pathway in the bitten/stung organism.
44643	envenomation resulting in positive regulation of complement activation, alternative pathway in other organism	P	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant positive regulation of complement activation via the alternative pathway in the bitten/stung organism.
44644	envenomation resulting in negative regulation of complement activation, alternative pathway in other organism	P	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant negative regulation of complement activation via the alternative pathway in the bitten/stung organism.
44645	modulation of complement activation in other organism	P	A process that modulates the frequency, rate or extent of complement activation in a different organism.
44646	envenomation resulting in modulation of complement activation in other organism	P	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the resultant modulation of complement activation in the bitten/stung organism.
44647	host-symbiont bicellular tight junction	C	An occluding cell-cell junction formed between the membranes of the apical end of an invading cell (e.g. a merozoite in Plasmodium) and a host target cell (e.g. erythrocyte for Plasmodium infection). The junction is a stable yet dynamic structure that moves around the symbiont cell during invasion, enclosing it in a vacuole surrounded by a membrane.
44648	histone H3-K4 dimethylation	P	The modification of histone H3 by addition of two methyl groups to lysine at position 4 of the histone.
44649	envenomation resulting in cytolysis in other organism	P	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with cytolysis in the bitten organism.
44650	adhesion of symbiont to host cell	P	The attachment of a symbiont to a host cell via adhesion molecules, general stickiness etc., either directly or indirectly.
44651	adhesion of symbiont to host epithelial cell	P	The attachment of a symbiont to a host epithelial cell via adhesion molecules, general stickiness etc., either directly or indirectly.
44652	adhesion of symbiont to host endothelial cell	P	The attachment of a symbiont to a host endothelial cell via adhesion molecules, general stickiness etc., either directly or indirectly.
44653	dextrin alpha-glucosidase activity	F	Catalysis of the reaction: dextrin + H2O = alpha-D-glucose.
44654	starch alpha-glucosidase activity	F	Catalysis of the reaction: starch + H2O = alpha-D-glucose.
44655	phagosome reneutralization	P	Any process that increases the pH of the phagosome, measured by the concentration of the hydrogen ion, as part of the process of phagosome maturation.
44656	regulation of post-lysosomal vacuole size	P	Any process that modulates the volume of a post-lysosomal vacuole, a membrane-bounded intracellular vesicle formed late in the endocytic pathway when the pH in the vacuole becomes neutral prior to exocytosis.
44657	pore formation in membrane of other organism during symbiotic interaction	P	The aggregation, arrangement and bonding together of a set of components by an organism to form a pore complex in a membrane of another organism, occurring as part of a symbiotic interaction.
44658	pore formation in membrane of host by symbiont	P	The aggregation, arrangement and bonding together of a set of components by an organism to form a pore complex in a membrane of a host organism.
44659	cytolysis by virus of host cell	P	The killing by a virus of a cell in its host organism by means of the rupture of cell membranes and the loss of cytoplasm.
44660	cytolysis by virus via pore formation in host cell membrane	P	The killing by a virus of a cell in its host organism by cytolysis, caused by the formation by the virus of pores in its host cell membrane.
44661	disruption by virus of host cell	P	A process by which a virus has a negative effect on the functioning of the host's cell.
44662	disruption by virus of host cell membrane	P	A process by which a virus has a negative effect on the functioning of a host cellular membrane.
44663	establishment or maintenance of cell type involved in phenotypic switching	P	A cellular process of the specification, formation or maintenance of an alternative cell type, occurring as part of the process of phenotypic switching. Phenotypic switching begins with changes in cell morphology and altered gene expression patterns and ends when the morphology of a population of cells has reverted back to the default state, accompanied by altered expression patterns.
44665	MLL1/2 complex	C	A protein complex that can methylate lysine-4 of histone H3, and which contains either of the protein subunits MLL1 or MLL2 in human, or equivalent in other species.
44666	MLL3/4 complex	C	A protein complex that can methylate lysine-4 of histone H3, and which contains either of the protein subunits MLL3 or MLL4 in mammals, or equivalent in other species.
44667	(R)-carnitine:4-(trimethylammonio)butanoate antiporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: (R)-carnitine(out) + 4-(trimethylammonio)butanoate(in) = (R)-carnitine(in) + 4-(trimethylammonio)butanoate(out).
44668	sodium:malonate symporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sodium(out)+ malonate(out) = sodium(in) + malonate(in).
44669	sodium:galactoside symporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sodium(out)+ galactoside(out) = sodium(in) + galactoside(in).
44670	sodium:alanine symporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sodium(out)+ alanine(out) = sodium(in) + alanine(in).
44671	sorocarp spore cell differentiation	P	The process in which a relatively unspecialized cell acquires specialized features of a sorocarp spore cell, a cell of the sorocarp sorus. A sorocarp is the fruiting body characteristic of certain cellular slime moulds (e.g., Dictyosteliida) and consists of both stalk and a sorus (spore mass).
44672	acetyl-CoA decarbonylase/synthase-carbon monoxide dehydrogenase complex	C	A multifunctional enzyme complex composed of five different polypeptides that catalyzes the decarbonylation of acetyl-CoA, cleaves the C-C and C-S bonds in the acetyl moiety of acetyl-CoA, oxidizes the carbonyl group to CO2 and transfers the methyl group to tetrahydrosarcinapterin. These reactions are important for methanogenesis.
44673	7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase complex	C	A heterodimer which catalyses the reaction of 5-amino-6-(D-ribitylamino)uracil and 4-hydroxyphenylpyruvate to form 7,8-didemethyl-8-hydroxy-5-deazariboflavin (FO), an intermediate of coenzyme F420.
44674	methyl coenzyme M reductase complex	C	A hexameric complex consisting of three polypeptides in an alpha2beta2gamma2 arrangement. Involved in the reduction of the coenzyme M-bound methyl group to methane, which is the final step in methanogenesis.
44675	formyl-methanofuran dehydrogenase (tungsten enzyme) complex	C	A protein complex consisting of four polypeptides which also contains tungsten, a molybdopterin guanine dinucleotide, and iron-sulfur clusters. This protein complex catalyzes the reversible conversion of CO2 and methanofuran to formylmethanofuran during methanogenesis.
44676	formyl-methanofuran dehydrogenase (molybdenum enzyme) complex	C	A protein complex consisting of three polypeptides which also contains molybdenum, a molybdopterin guanine dinucleotide and iron-sulfur clusters. This protein complex catalyzes the reversible conversion of CO2 and methanofuran to formylmethanofuran during methanogenesis.
44677	methyl-tetrahydromethanopterin:coenzyme M methyltransferase complex	C	A protein complex consisted of eight polypeptides. This complex catalyzes the formation of methyl-coenzyme M and H4MPT from N5-methyl-H4MPT and CoM during methanogenesis.
44678	CoB-CoM heterodisulfide reductase complex	C	A protein complex that in Methanobacterium thermoautotrophicum is composed of six subunits, and in Methanosarcina barkeri contains is composed of either two subunits or nine subunits. Catalyzes the conversion of coenzyme B, coenzyme M, and methanophenazine to form N-{7-[(2-sulfoethyl)dithio]heptanoyl}-3-O-phospho-L-threonine and dihydromethanophenazine.
44679	methanophenazine reducing hydrogenase complex	C	A protein complex which catalyzes the conversion of methanophenazine and hydrogen to form dihydromethanophenazine. This typically consists of three polypeptides
44680	methylthiol:coenzyme M methyltransferase complex	C	A protein complex of two polypeptides which catalyzes the transfer of methyl group from methylthiol to coenzyme M during methanogenesis.
44681	sulfopyruvate decarboxylase complex	C	A complex of two polypeptides which form a dodecamer (A6B6). Catalyzes the decarboxylation of sulfopyruvic acid to sulfoacetaldehyde. This reaction is involved in coenzyme M biosynthesis.
44682	archaeal-specific GTP cyclohydrolase activity	F	Catalysis of the reaction: GTP + H2O <=> 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate + diphosphate +formate + H+. This activity is part of the biosynthesis of methanopterin in Archaea, and requires Fe2+.
44683	methylthiol:coenzyme M methyltransferase activity	F	Catalysis of the overall reaction: methyl-Co(III) methylated-thiol-specific corrinoid protein + coenzyme M = Co(I) methylated--thiol-specific corrinoid protein + methyl-CoM.
44684	dihydromethanopterin reductase activity	F	Catalysis of the reaction: 7,8-dihydromethanopterin + NADPH = 5,6,7,8-tetrahydromethanopterin + NADP.
44685	tetrahydromethanopterin-dependent serine hydroxymethyltransferase activity	F	Catalysis of the reaction: tetrahydromethanopterin + L-serine = 5,10-methylenetetrahydromethanopterin + glycine + H2O.
44686	cysteate synthase activity	F	Catalysis of the reaction: L-phosphoserine + SO32- = L-cysteate + HPO4-.
44687	geranylfarnesyl diphosphate synthase activity	F	Catalysis of the reaction: geranylgeranyl diphosphate + isopentenyl diphosphate = (2E,6E,10E,14E)-geranylfarnesyl diphosphate + diphosphate.
44688	7,8-dihydro-D-neopterin 2',3'-cyclic phosphate phosphodiesterase activity	F	Catalysis of the reaction: 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate + H2O = 7,8-dihydroneopterin 3'-phosphate + H+.
44689	7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase activity	F	Catalysis of the reaction: 5-amino-6-(D-ribitylamino)uracil + 4-hydroxyphenylpyruvate + 2 S-adenosyl-L-methionine + H2O = 7,8-didemethyl-8-hydroxy-5-deazariboflavin + 2 5'-deoxyadenosine + 2 L-methionine + oxalate + ammonia + 4 H+.
44690	methionine import	P	The directed movement of methionine into a cell or organelle.
44691	tooth eruption	P	The tooth development process in which the teeth enter the mouth and become visible.
44692	exoribonuclease activator activity	F	Binds to and increases the activity of an exoribonuclease.
44693	trehalose:proton symporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: trehalose(out) + H+(out) = trehalose(in) + H+(in).
44694	pore-mediated entry of viral genome into host cell	P	Injection by a non-enveloped virus of the viral genome into the host cytoplasm through creation of a pore or channel in the host cell membrane(s). Usually mediated by a viral pore-forming peptide associated with the viral capsid or bacteriophage tail.
44695	Dsc E3 ubiquitin ligase complex	C	An E3 ubiquitin ligase complex localized to the ER and Golgi membrane. In fission yeast comprises Dsc1, 2, 3 and 4. Involved in the processes of fission yeast sre1 (human SREBP) transcriptional activator proteolytic cleavage, the multivesicular body (MVB) pathway, and a post-endoplasmic reticulum pathway for protein catabolism.
44696	killing by virus of host cell by post-segregational killing	P	The process by which a virus causes the death of daughter cells which do not contain its genes after host cell division, by a mechanism of post-segregational killing (PSK). The extrachromosomal viral DNA consist of two genes; the product of the second is long lived and toxic, while the product of the first is short lived and antagonizes the lethal action of the toxin. Daughter cells that do not contain the viral extrachromosomal element are killed by the long lived toxin, while daughter cells that do contain the viral extrachromosomal element are protected by the action of the short lived antitoxin it encodes.
44697	HICS complex	C	A multisubunit complex involved in cytokinesis. In the yeast Saccharomyces cerevisiae this complex consists of Sho1p, Hof1p, Inn1p and Cyk3p proteins.
44698	morphogenesis of symbiont in host cell	P	The process in which a symbiont undergoes a change in shape or form, within the host's cell.
44699	single-organism process	P	A biological process that involves only one organism.
44700	single organism signaling	P	A signaling process occurring within a single organism.
44702	single organism reproductive process	P	A biological process that directly contributes to the process of producing new individuals, involving a single organism.
44703	multi-organism reproductive process	P	A biological process that directly contributes to the process of producing new individuals, involving another organism.
44704	single-organism reproductive behavior	P	The specific behavior of an organism that is associated with reproduction involving a single organism.
44705	multi-organism reproductive behavior	P	The specific behavior of an organism that is associated with reproduction involving another organism of the same or different species.
44706	multi-multicellular organism process	P	A multicellular organism process which involves another multicellular organism of the same or different species.
44707	single-multicellular organism process	P	A biological process occurring within a single, multicellular organism.
44708	single-organism behavior	P	The specific behavior of a single organism in response to external or internal stimuli.
44710	single-organism metabolic process	P	A metabolic process - chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances - which involves a single organism.
44711	single-organism biosynthetic process	P	A biosynthetic process - chemical reactions and pathways resulting in the formation of substances - involving a single organism.
44712	single-organism catabolic process	P	A catabolic process - chemical reactions and pathways resulting in the breakdown of substances - which involves a single organism.
44713	2-hydroxy-adenosine triphosphate pyrophosphatase activity	F	Catalysis of the reaction: 2-hydroxy-adenosine-triphosphate + H2O = 2-hydroxy-adenosine phosphate + diphosphate.
44714	2-hydroxy-(deoxy)adenosine-triphosphate pyrophosphatase activity	F	Catalysis of the reaction: 2-hydroxy-(deoxy)adenosine-triphosphate + H2O = 2-hydroxy-(deoxy)adenosine phosphate + diphosphate.
44715	8-oxo-dGDP phosphatase activity	F	Catalysis of the reaction 8-oxo-dGDP + H2O = 8-oxo-dGMP + phosphate.
44716	8-oxo-GDP phosphatase activity	F	Catalysis of the reaction 8-oxo-GDP + H2O = 8-oxo-GMP + phosphate.
44717	8-hydroxy-dADP phosphatase activity	F	Catalysis of the reaction8-hydroxy-dADP + H2O = 8-hydroxy-dAMP + phosphate.
44718	siderophore transmembrane transport	P	The directed movement of siderophores, low molecular weight Fe(III)-chelating substances, from one side of a membrane to the other, by means of some agent such as a transporter or pore.
44719	regulation of imaginal disc-derived wing size	P	Any process that modulates the size of an imaginal disc-derived wing.
44720	negative regulation of imaginal disc-derived wing size	P	Any process that reduces the size of an imaginal disc-derived wing.
44721	protein import into peroxisome matrix, substrate release	P	The process by which the cargo protein is released into the peroxisomal matrix, following translocation across the membrane.
44722	renal phosphate excretion	P	The elimination by an organism of phosphate ions in the urine.
44723	single-organism carbohydrate metabolic process	P	The chemical reactions and pathways involving carbohydrates, occurring within a single organism.
44724	single-organism carbohydrate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of carbohydrates, occurring within a single organism.
44725	chromatin reprogramming in the zygote	P	The global reprogramming of epigenetic modifications in the zygote following fertilization. The paternal genome undergoes active DNA demethylation before the first cell division, while the adjacent maternal genome is protected from this process.
44726	protection of DNA demethylation of female pronucleus	P	The protection of the maternal genome from DNA demethylation in the zygote following fertilization.
44727	DNA demethylation of male pronucleus	P	The active DNA demethylation of the paternal genome that takes place before the first cell division.
44728	DNA methylation or demethylation	P	The process of adding or removing a methyl group from one or more nucleotides within an DNA molecule.
44729	hemi-methylated DNA-binding	F	Interacting selectively and non-covalently with double-stranded hemi-methylated DNA at replication foci (one strand methylated, while the other strand is unmethylated). Methylation of cytosine or adenine in DNA is an important mechanism for establishing stable heritable epigenetic marks.
44730	bone sialoprotein binding	F	Interacting selectively and non-covalently with a bone sialoprotein, an extracellular matrix glycoprotein found on the surface of bones and dentin.
44731	Ost-alpha/Ost-beta complex	C	A heterodimeric protein complex composed of Ost-alpha/SLC51A and Ost-beta/SLC51B subunits and involved in bile acid transport activity.
44732	mitotic spindle pole body	C	The microtubule organizing center that forms as part of the mitotic cell cycle; functionally homologous to the animal cell centrosome.
44733	envenomation resulting in modulation of acid-sensing ion channel activity in other organism	P	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with a resultant change in the activity of an acid-sensing ion channel (ASIC) in the bitten organism.
44734	envenomation resulting in positive regulation of acid-sensing ion channel activity in other organism	P	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with a resultant positive regulation in the activity of an acid-sensing ion channel (ASIC) in the bitten organism.
44735	envenomation resulting in negative regulation of acid-sensing ion channel activity in other organism	P	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with a resultant negative regulation in the activity of an acid-sensing ion channel (ASIC) in the bitten organism.
44736	acid-sensing ion channel activity	F	Enables the transmembrane transfer of a sodium ion by a neuronal, voltage-insensitive channel that opens when a an extracellular proton has been bound by the channel complex.
44737	modulation of acid-sensing ion channel in other organism	P	Any process in which an organism effects a change in the frequency, rate or extent of the activity of an acid-sensing ion channel (ASIC) in another organism.
44738	negative regulation of acid-sensing ion channel in other organism	P	Any process in which an organism negatively regulates the activity of a voltage-gated sodium channel in another organism.
44739	positive regulation of acid-sensing ion channel in other organism	P	Any process in which an organism positively regulates the activity of a voltage-gated sodium channel in another organism.
44740	negative regulation of sensory perception of pain in other organism	P	A process that negatively regulates the sensory perception of pain in a different organism.
44741	envenomation resulting in negative regulation of sensory perception of pain in other organism	P	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the inhibition of the sensory perception of pain in the bitten organism.
44742	envenomation resulting in modulation of sensory perception of pain in other organism	P	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the modulation of the sensory perception of pain in the bitten organism.
44743	intracellular protein transmembrane import	P	The directed movement of proteins into an intracellular organelle, across a membrane.
44744	protein targeting to nucleus	P	The process of directing proteins towards the nucleus, usually using signals contained within the protein.
44745	amino acid transmembrane import	P	The directed movement of amino acids into a cell or organelle, across a membrane.
44746	amino acid transmembrane export	P	The directed movement of amino acids out of a cell or organelle across a membrane.
44747	mature miRNA 3'-end processing	P	Any process involved in forming distinct miRNA isoforms from a mature miRNA that differ at their 3'-ends.
44748	3'-5'-exoribonuclease activity involved in mature miRNA 3'-end processing	F	Catalysis of the sequential cleavage of mononucleotides from a free 3' terminus of an RNA molecule that contributes to forming distinct miRNA isoforms from a mature miRNA.
44749	high-affinity zinc II ion transmembrane import	P	The directed, high-affinity movement of zinc (Zn II) ions across a membrane into a cell or organelle. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.
44750	high-affinity nickel cation transmembrane transporter activity	F	Catalysis of the high-affinity transfer of nickel (Ni) cations from one side of a membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.
44751	cellular response to human chorionic gonadotropin stimulus	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a human chorionic gonadotropin stimulus.
44752	response to human chorionic gonadotropin	P	Any process that results in a change in state or activity of a cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a human chorionic gonadotropin stimulus.
44753	amphisome	C	An autophagosome formed upon fusion between autophagosomes and endosomes.
44754	autolysosome	C	A type of secondary lysosome in which a primary lysosome has fused with the outer membrane of an autophagosome. It is involved in the second step of autophagy in which it degrades contents with acidic lysosomal hydrolases.
44755	pantothenate import into cell	P	The directed movement of pantothenate from outside of a cell into the cytoplasmic compartment. This may occur via transport across the plasma membrane or via endocytosis.
44756	biotin import into cell	P	The directed movement of biotin from outside of a cell into the cytoplasmic compartment. This may occur via transport across the plasma membrane or via endocytosis.
44757	dethiobiotin import into cell	P	The directed movement of dethiobiotin from outside of a cell into the cytoplasmic compartment. This may occur via transport across the plasma membrane or via endocytosis.
44758	modulation by symbiont of host synaptic transmission	P	Any process in which a symbiont organism modulates the frequency, rate or extent of synaptic transmission, communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse, in its host organism.
44759	negative regulation by symbiont of host synaptic transmission	P	Any process in which a symbiont organism decreases the frequency, rate or extent of synaptic transmission, communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse, in its host organism.
44760	modulation by symbiont of host cholinergic synaptic transmission	P	Any process in which a symbiont organism modulates the frequency, rate or extent of cholinergic synaptic transmission, communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse via the neurotransmitter choline, in its host organism.
44761	negative regulation by symbiont of host cholinergic synaptic transmission	P	Any process in which a symbiont organism negatively regulates cholinergic synaptic transmission, communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse via the neurotransmitter choline, in its host organism.
44762	negative regulation by symbiont of host neurotransmitter secretion	P	Any process in which a symbiont organism negatively regulates the regulated release of a neurotransmitter from a cell in its host organism.
44763	single-organism cellular process	P	Any process that is carried out at the cellular level, occurring within a single organism.
44764	multi-organism cellular process	P	Any process that is carried out at the cellular level which involves another organism of the same or different species.
44765	single-organism transport	P	The directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter or pore, involving a single organism.
44766	multi-organism transport	P	The directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter or pore, involving more than one organism.
44767	single-organism developmental process	P	A biological process whose specific outcome is the progression of an integrated living unit: an anatomical structure (which may be a subcellular structure, cell, tissue, or organ), or organism over time from an initial condition to a later condition, involving only one organism.
44768	NMS complex assembly	P	The aggregation, arrangement and bonding together of a set of components to form an NMS complex. The NMS complex results from the association of two subcomplexes (known as MIND and Ndc80 in Schizosaccharomyces) and is required for kinetochore assembly.
44769	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism	F	Catalysis of the transfer of ions from one side of a membrane to the other according to the reaction: ATP + H2O + ion(in) = ADP + phosphate + ion(out), by a rotational mechanism.
44770	cell cycle phase transition	P	The cell cycle process by which a cell commits to entering the next cell cycle phase.
44771	meiotic cell cycle phase transition	P	The cell cycle process by which a cell commits to entering the next meiotic cell cycle phase.
44772	mitotic cell cycle phase transition	P	The cell cycle process by which a cell commits to entering the next mitotic cell cycle phase.
44773	mitotic DNA damage checkpoint	P	A mitotic cell cycle checkpoint that detects and negatively regulates progression through the cell cycle in response to DNA damage.
44774	mitotic DNA integrity checkpoint	P	A mitotic cell cycle process that controls cell cycle progression in response to changes in DNA structure by monitoring the integrity of the DNA. The DNA integrity checkpoint begins with detection of DNA damage, defects in DNA structure or DNA replication, and ends with signal transduction.
44775	DNA polymerase III, beta sliding clamp processivity factor complex	C	A subcomplex of the DNA polymerase III holoenzyme which is responsible for tethering the catalytic subunit of DNA polymerase to DNA during high-speed replication. The complex is homodimeric in prokaryotes, and homotrimeric in other species.
44776	DNA polymerase III, core complex	C	The DNA polymerase III core complex consists of the alpha,epsilon and theta subunits and is carries out the polymerase and the 3'-5' exonuclease proofreading activities.
44777	single-stranded DNA-binding protein complex	C	A homotetrameric protein complex that is essential for DNA replication. It supercoils the single-stranded DNA preventing DNA duplexing before the polymerase holoenzyme passes and synthesizes the complementary strand. It is also involved in DNA recombination and repair.
44778	meiotic DNA integrity checkpoint	P	A meiotic cell cycle process that controls cell cycle progression in response to changes in DNA structure by monitoring the integrity of the DNA. The DNA integrity checkpoint begins with detection of DNA damage, defects in DNA structure or DNA replication, and ends with signal transduction.
44779	meiotic spindle checkpoint	P	A cell cycle checkpoint that delays the metaphase/anaphase transition of a meiotic nuclear division until the spindle is correctly assembled and that the chromosomes are attached to the spindle.
44780	bacterial-type flagellum assembly	P	The assembly of a bacterial-type flagellum, a motor complex composed of an extracellular helical protein filament coupled to a rotary motor embedded in the cell envelope which functions in cell motility.
44781	bacterial-type flagellum organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a bacterial-type flagellum, a motor complex composed of an extracellular helical protein filament coupled to a rotary motor embedded in the cell envelope which functions in cell motility.
44782	cilium organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cilium, a specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole.
44783	G1 DNA damage checkpoint	P	A cell cycle checkpoint that detects and negatively regulates progression from G1 to S phase in the cell cycle in response to DNA damage.
44784	metaphase/anaphase transition of cell cycle	P	The cell cycle process in which a cell progresses from metaphase to anaphase as part of the cell cycle.
44785	metaphase/anaphase transition of meiotic cell cycle	P	The cell cycle process in which a cell progresses from metaphase to anaphase as part of meiosis.
44786	cell cycle DNA replication	P	The DNA-dependent DNA replication that takes place as part of the cell cycle.
44787	bacterial-type DNA replication	P	The DNA-dependent DNA replication, exemplified by prokaryotes, that occurs as part of the cell cycle. Prokaryotic DNA replication is bi-directional and originates at a single origin of replication on the circular genome.
44788	modulation by host of viral process	P	A process in which a host organism modulates the frequency, rate or extent of any of a process being mediated by a virus with which it is infected.
44789	modulation by host of viral release from host cell	P	A process in which a host organism modulates the frequency, rate or extent of the release of a virus with which it is infected, from its cells.
44790	negative regulation by host of viral release from host cell	P	A process in which a host organism stops, prevents or reduces the frequency, rate or extent of the release of a virus with which it is infected, from its cells.
44791	positive regulation by host of viral release from host cell	P	A process in which a host organism activates or increases the frequency, rate or extent of the release of a virus with which it is infected, from its cells.
44793	negative regulation by host of viral process	P	A process in which a host organism stops, prevents or reduces the frequency, rate or extent of a process being mediated by a virus with which it is infected.
44794	positive regulation by host of viral process	P	A process in which a host organism activates or increases the frequency, rate or extent of the release of a process being mediated by a virus with which it is infected.
44795	trans-Golgi network to recycling endosome transport	P	The directed movement of substances, in membrane-bounded vesicles, from the trans-Golgi network to the recycling endosomes.
44796	DNA polymerase processivity factor complex	C	A protein complex which is capable of increasing the processivity of nucleotide polymerization by DNA polymerase as a part of DNA replication.
44797	cytoplasmic transcription factor complex	C	A protein complex, located in the cytoplasm, that is capable of associating with DNA by direct binding, or via other DNA-binding proteins or complexes, and regulating transcription.
44798	nuclear transcription factor complex	C	A protein complex, located in the nucleus, that is capable of associating with DNA by direct binding, or via other DNA-binding proteins or complexes, and regulating transcription.
44799	NarGHI complex	C	A heterotrimeric protein complex with iron-sulfur and molybdenum cofactors that functions as a terminal reductase in electron transport pathways that operate during anaerobic nitrate respiration. In E. coli electrons are passed from the FdnGHI complex to the NarGHI complex via menoquinone and menaquinol. Within NarGHI, electrons are passed from the two heme molecules in the NarI subunit down a Fe-S cluster chain in the NarH and NarG subunits to the Molybdenum cofactor, Mo-bisMGD, in the NarG subunit.
44800	multi-organism membrane fusion	P	The membrane organization process that joins two lipid bilayers to form a single membrane, involving more than one organism.
44801	single-organism membrane fusion	P	The membrane organization process that joins two lipid bilayers to form a single membrane, involving only one organism.
44802	single-organism membrane organization	P	A process which results in the assembly, arrangement of constituent parts, or disassembly of a membrane, involving only one organism.
44803	multi-organism membrane organization	P	A process which results in the assembly, arrangement of constituent parts, or disassembly of a membrane, involving more than one organism.
44804	nucleophagy	P	A selective form of autophagy, by which damaged or non-essential parts of the nucleus, or even an entire nucleus is degraded.
44805	late nucleophagy	P	A type of nucleophagy, distinct from piecemeal microautophagy of the nucleus (PNM) where the nuclear material is delivered to the vacuole/lysosome for breakdown and recycling later than observed for PNM.
44806	G-quadruplex DNA unwinding	P	The process by which G-quadruplex (also known as G4) DNA, which is a four-stranded DNA structure held together by guanine base pairing, is unwound or 'melted'.
44807	macrophage migration inhibitory factor production	P	The appearance of macrophage migration inhibitory factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
44808	Oncostatin M production	P	The appearance of Oncostatin M due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
44809	chemokine (C-C motif) ligand 17 production	P	The appearance of chemokine (C-C motif) ligand 17 (CCL17) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
44810	Dma1-dependent checkpoint	P	Mitotic cell cycle spindle checkpoint that negatively regulates cytokinesis and mitotic exit when the spindle does not form.
44811	response to Dma1-dependent checkpoint signaling	P	A process that occurs in response to signals generated as a result of Dma1-dependent checkpoint signalling.
44812	fermentative hydrogen production	P	The fermentation of organic substances with a net release of hydrogen.
44813	glycolytic fermentation via PFOR pathway	P	The glycolytic fermentation beginning with the anaerobic conversion of glucose to pyruvate by the glycolytic pathway, continuing with pyruvate:ferredoxin oxidoreductase (PFOR) activity. This pathway is found in strict anaerobes such as Clostridia species.
44814	glycolytic fermentation via PFL pathway	P	The glycolytic fermentation beginning with the anaerobic conversion of glucose to pyruvate by the glycolytic pathway, followed by pyruvate:formate lyase (PFL) activity. This pathway is found in facultative anaerobes such as E. coli.
44815	DNA packaging complex	C	A protein complex that plays a role in the process of DNA packaging.
44816	Nsk1-Dlc1 complex	C	A dimer of Nsk1 (nucleolus spindle kinetochore 1) and the dynein light chain, Dlc1. The dimers form an oligomeric chain structure. Functions in the regulation of kinetochore-microtubule interactions and chromosome segregation.
44817	hydrogen generation via biophotolysis	P	The production of hydrogen which results from the dissociation by light of water into molecular hydrogen and oxygen. This process is observed in cyanobacteria and microalgae.
44818	mitotic G2/M transition checkpoint	P	A cell cycle checkpoint that detects and negatively regulates progression from G2 to M phase as part of a mitotic cell cycle.
44819	mitotic G1/S transition checkpoint	P	A cell cycle checkpoint that detects and negatively regulates progression from G1 to S phase as part of a mitotic cell cycle.
44820	mitotic telomere tethering at nuclear periphery	P	The process in which a telomere is maintained in a specific location at the nuclear periphery, as part of a mitotic cell cycle.
44821	meiotic telomere tethering at nuclear periphery	P	The process in which a telomere is maintained in a specific location at the nuclear periphery, as part of a meiotic cell cycle.
44822	poly(A) RNA binding	F	Interacting non-covalently with a poly(A) RNA, an RNA molecule which has a tail of adenine bases.
44823	retroviral integrase activity	F	Catalysis of the covalent insertion of double-stranded retroviral DNA into host DNA. Proceeds by an endonucleolytic cleavage at each 3'-OH extremity of the viral genome, named 3'-processing, followed by a strand transfer reaction leading to the insertion of the processed viral DNA into the target DNA by a trans-esterification mechanism.
44824	retroviral 3' processing activity	F	The catalysis of the removal of two di- or tri-nucleotides from each 3' end of double-stranded viral DNA, exposing recessed 3' hydroxyls.
44825	retroviral strand transfer activity	F	Catalysis of the covalent insertion of processed 3'-viral DNA ends into host chromosomal DNA by a trans-esterification reaction.
44826	viral genome integration into host DNA	P	The insertion into a host genome of viral DNA, usually by the action of an integrase enzyme. Once integrated, the provirus persists in the host cell and serves as a template for the transcription of viral genes and replication of the viral genome, leading to the production of new viruses.
44827	modulation by host of viral genome replication	P	A process in which a host organism modulates the frequency, rate or extent of viral genome replication.
44828	negative regulation by host of viral genome replication	P	A process in which a host organism stops, prevents or reduces the frequency, rate or extent of viral genome replication.
44829	positive regulation by host of viral genome replication	P	A process in which a host organism activates or increases the frequency, rate or extent of viral genome replication.
44830	modulation by host of viral RNA genome replication	P	A process in which a host organism modulates the frequency, rate or extent of viral RNA genome replication.
44831	modulation by virus of host cytokine production	P	Any process in which a virus modulates the frequency, rate or extent of cytokine production in its host organism.
44832	positive regulation by virus of host cytokine production	P	The process in which a virus increases the frequency, rate or extent of cytokine production in its host organism.
44833	modulation by virus of host protein transport	P	Any viral process that modulates the frequency, rate or extent of protein transport in its host organism.
44834	retroviral intasome	C	A tetramer of retroviral integrase subunits tightly associated with a pair of viral DNA ends. Functions to insert viral DNA into a host cell chromosome.
44835	hydrogen generation via nitrogenase	P	The chemical reactions and pathways resulting in the formation of H2 (dihydrogen) which involve a nitrogenase activity as one of the steps. This process is observed in cyanobacteria.
44836	D-xylose fermentation	P	The anaerobic enzymatic conversion of D-xylose to ethanol, yielding energy in the form of ATP.
44837	actomyosin contractile ring organization	P	A process which results in the assembly, arrangement of constituent parts, or disassembly of an actomyosin contractile ring.
44838	cell quiescence	P	A specialized resting state that cells enter in response to cues from the cell's environment. Quiescence is characterized by the absence of cell growth and division, by a reprogramming of global gene expression, and by changes characteristic of the organism and specific cell type. Depending on external conditions, quiescence may persist until cell death or cells may resume cell growth and division. In some cell types or under certain conditions, cellular metabolism may proceed.
44839	cell cycle G2/M phase transition	P	The cell cycle process by which a cell in G2 phase commits to M phase.
44840	gut granule	C	A lysosome-related organelle contained within the intestinal cells of the nematode C. elegans. Gut granules are acidified, birefringent, autofluorescent, and contain the vacuolar H+-ATPase. They also serve as sites of cellular zinc storage.
44841	gut granule membrane	C	The membrane of a gut granule, a lysosome-related organelle contained within the intestinal cells of the nematode C. elegans.
44842	gut granule lumen	C	The lumen of a gut granule, a lysosome-related organelle contained within the intestinal cells of the nematode C. elegans.
44843	cell cycle G1/S phase transition	P	The cell cycle process by which a cell in G1 phase commits to S phase.
44844	meiotic interphase II	P	The cell cycle phase which begins at the end of meiosis I cytokinesis and ends when meiosis II prophase begins. During meiotic interphase II no DNA replication takes place, but the centrioles duplicate and spindle fibres emerge.
44845	chain elongation of O-linked mannose residue	P	Extension of the O-linked mannose residue of a mannoprotein by the stepwise addition of further mannose molecules.
44846	negative regulation by symbiont of indole acetic acid levels in host	P	Any process in which an organism reduces the indole acetic acid levels in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
44847	iron acquisition by symbiont from host	P	The process by which a symbiont acquires iron from its host, either from heme or other iron containing molecules such as transferrin and lactoferrin. Begins with either the secretion of symbiont gene products that bind iron- or heme-containing molecules (siderophores and hemophores) from the symbiont cell into the host, or by expression of receptors that bind iron- or heme-containing molecules on the symbiont cell surface. Ends when the iron-containing compound is transported into the symbiont cell.
44848	biological phase	P	A distinct period or stage in a biological process or cycle.
44849	estrous cycle	P	A type of ovulation cycle, which occurs in most mammalian therian females, where the endometrium is resorbed if pregnancy does not occur.
44850	menstrual cycle	P	A type of ovulation cycle where the endometrium is shed if pregnancy does not occur.
44851	hair cycle phase	P	The cyclical periods of growth (anagen), regression (catagen), quiescence (telogen), and shedding (exogen) in the life of a hair; one of the collection or mass of filaments growing from the skin of an animal, and forming a covering for a part of the head or for any part or the whole of the body.
44852	nonrepetitive DNA condensation	P	The process in which chromatin structure of nonrepetitive regions of DNA is compacted prior to and during mitosis in eukaryotic cells.
44853	plasma membrane raft	C	A membrane raft that is part of the plasma membrane.
44854	plasma membrane raft assembly	P	The aggregation, arrangement and bonding together of a set of components to form a plasma membrane raft.
44855	plasma membrane raft distribution	P	The process that establishes the spatial arrangement of membrane rafts within a plasma membrane.
44856	plasma membrane raft localization	P	Any process in which plasma membrane rafts are transported to, or maintained in, a specific location.
44857	plasma membrane raft organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of plasma membrane rafts.
44858	plasma membrane raft polarization	P	The clustering and aggregation of plasma membrane rafts at a single cellular pole during activation of particular cell types, such as lymphocytes.
44859	protein insertion into plasma membrane raft	P	The process in which a protein is incorporated into a plasma membrane raft.
44860	protein localization to plasma membrane raft	P	A process in which a protein is transported to, or maintained in, a location within a plasma membrane raft.
44861	protein transport into plasma membrane raft	P	The directed movement of a protein into a plasma membrane raft.
44862	protein transport out of plasma membrane raft	P	The directed movement of a protein out of a plasma membrane raft.
44863	modulation by virus of host cell division	P	Any process where an infecting virus modulates the frequency, rate or extent of the physical partitioning and separation of its host's cell into daughter cells.
44864	positive regulation by virus of host cell division	P	Any process where an infecting virus activates or increases the frequency, rate or extent of its host's cell division.
44865	negative regulation by virus of host cell division	P	Any process where an infecting virus stops, prevents, or reduces the frequency, rate or extent of its host's cell division.
44866	modulation by host of viral exo-alpha-sialidase activity	P	The process in which a host organism effects a change in viral exo-alpha-sialidase activity, the catalysis of the hydrolysis of peptide bonds in a protein.
44867	modulation by host of viral catalytic activity	P	The process in which a host organism effects a change in the enzyme activity of a virus with which it is infected.
44868	modulation by host of viral molecular function	P	A process in which a host organism modulates the frequency, rate or extent of any molecular function being mediated by a virus with which it is infected.
44869	negative regulation by host of viral exo-alpha-sialidase activity	P	The process in which a host organism decreases viral exo-alpha-sialidase activity, the catalysis of the hydrolysis of peptide bonds in a protein.
44870	modulation by host of viral glycoprotein metabolic process	P	A process in which a host organism modulates the frequency, rate or extent of viral glycoprotein metabolic process.
44871	negative regulation by host of viral glycoprotein metabolic process	P	A process in which a host organism stops, prevents or reduces the frequency, rate or extent of viral glycoprotein metabolic process.
44872	lipoprotein localization	P	Any process in which a lipoprotein is transported to, or maintained in, a specific location.
44873	lipoprotein localization to membrane	P	A process in which a lipoprotein is transported to, or maintained in, a specific location in a membrane.
44874	lipoprotein localization to outer membrane	P	A process in which a lipoprotein is transported to, or maintained in, a specific location in an outer membrane.
44875	gamma-glutamyl hercynylcysteine sulfoxide synthase	F	Catalysis of the reaction: gamma-glutamyl cysteine + hercynine + O2 <=> gamma-glutamyl-hercynyl cysteine sulfoxide + H2O.
44876	hercynylselenocysteine synthase	F	Catalysis of the reaction: 2 L-selenocysteine + 2 hercynine + O2 <=> 2 H2O + 2 hercynylselenocysteine.
44877	macromolecular complex binding	F	Interacting selectively and non-covalently with any macromolecular complex.
44878	mitotic cytokinesis checkpoint	P	A mitotic cell cycle checkpoint that detects a defect in cytokinesis and prevents further rounds of nuclear division until cytokinesis is completed.
44879	morphogenesis checkpoint	P	A mitotic cell cycle checkpoint which delays mitotic onset in response to perturbations that affect cell shape via the actin cytoskeleton, septin organization, small cell size, and/or the extent of membrane growth.
45002	double-strand break repair via single-strand annealing	P	Repair of a DSB made between two repeated sequences oriented in the same direction occurs primarily by the single strand annealing pathway. The ends of the break are processed by a 5' to 3' exonuclease, exposing complementary single-strand regions of the direct repeats that can anneal, resulting in a deletion of the unique DNA between the direct repeats.
45003	double-strand break repair via synthesis-dependent strand annealing	P	SDSA is a major mechanism of double-strand break repair in mitosis which allows for the error-free repair of a double-strand break without the exchange of adjacent sequences. The broken DNA searches for and base pairs with a homologous region in an intact chromosome. DNA synthesis initiates from the 3' end of the invading DNA strand, using the intact chromosome as the template. Newly synthesized DNA is then displaced from the template and anneal with its complement on the other side of the double-strand break.
45004	DNA replication proofreading	P	Correction of replication errors by DNA polymerase using a 3'-5' exonuclease activity.
45005	DNA-dependent DNA replication maintenance of fidelity	P	A DNA metabolic process that prevents or corrects errors to ensure that DNA is replicated accurately. Errors can be corrected either by intrinsic DNA polymerase proofreading activity or via mismatch repair.
45006	DNA deamination	P	The removal of an amino group from a nucleotide base in DNA. An example is the deamination of cytosine to produce uracil.
45007	depurination	P	The disruption of the bond between the sugar in the backbone and the A or G base, causing the base to be removed and leaving a depurinated sugar.
45008	depyrimidination	P	The disruption of the bond between the sugar in the backbone and the C or T base, causing the base to be removed and leaving a depyrimidinated sugar.
45009	chitosome	C	An intracellular membrane-bounded particle found in fungi and containing chitin synthase; it synthesizes chitin microfibrils. Chitin synthase activity exists in chitosomes and they are proposed to act as a reservoir for regulated transport of chitin synthase enzymes to the division septum.
45010	actin nucleation	P	The initial step in the formation of an actin filament, in which actin monomers combine to form a new filament. Nucleation is slow relative to the subsequent addition of more monomers to extend the filament.
45013	carbon catabolite repression of transcription	P	A transcription regulation process in which the presence of one carbon source leads to a decrease in the frequency, rate, or extent of transcription of specific genes involved in the metabolism of other carbon sources. Carbon catabolite repression is a mechanism of genetic regulation which the accumulation of catabolites of one substance in the cell represses the formation of enzymes that contribute to the catabolism of other substances.
45014	negative regulation of transcription by glucose	P	Any process involving glucose that stops, prevents or reduces the rate of transcription. The presence of glucose in the growth medium inhibits the synthesis of certain enzymes in bacteria growing on the medium. For example, transcription of some catabolic operons is under negative control by specific repressors and glucose is an anti-inducer of xylose utilization and glycerol kinase.
45015	HDEL sequence binding	F	Interacting selectively and non-covalently with a HDEL sequence, the C terminus tetrapeptide sequence His-Asp-Glu-Leu found in proteins that are to be retained in the endoplasmic reticulum.
45016	mitochondrial magnesium ion transport	P	The transport of magnesium ions (Mg2+) into, out of or within a mitochondrion. Transport across the mitochondrial membranes is mediated by a mitochondrial inner membrane protein.
45017	glycerolipid biosynthetic process	P	The chemical reactions and pathways resulting in the formation of glycerolipids, any lipid with a glycerol backbone.
45018	retrograde transport, vacuole to Golgi	P	The directed movement of substances from the vacuole to the trans-Golgi network; this occurs in yeast via the prevacuolar/endosomal compartment.
45019	negative regulation of nitric oxide biosynthetic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of nitric oxide.
45022	early endosome to late endosome transport	P	The directed movement of substances, in membrane-bounded vesicles, from the early sorting endosomes to the late sorting endosomes; transport occurs along microtubules and can be experimentally blocked with microtubule-depolymerizing drugs.
45023	G0 to G1 transition	P	The mitotic cell cycle phase transition whose occurrence commits the cell from the G0 quiescent state to the G1 phase. Under certain conditions, cells exit the cell cycle during G1 and remain in the G0 state as nongrowing, non-dividing (quiescent) cells. Appropriate stimulation of such cells induces them to return to G1 and resume growth and division. The G0 to G1 transition is accompanied by many changes in the program of gene expression.
45025	mitochondrial degradosome	C	A mitochondrial protein complex with 3' to 5' exoribonuclease activity that participates in intron-independent turnover and processing of mitochondrial transcripts. In humans, the mitochondrial degradosome is a pentameric complex, and in yeast it exists as a heterodimer.
45026	plasma membrane fusion	P	The joining of two or more lipid bilayer membranes that surround a cell.
45027	DNA end binding	F	Interacting selectively and non-covalently with the ends of DNA that are exposed by the creation of double-strand breaks (DSBs).
45028	G-protein coupled purinergic nucleotide receptor activity	F	Combining with a purine nucleotide and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.
45029	UDP-activated nucleotide receptor activity	F	Combining with a nucleotide and transmitting the signal to a heterotrimeric G-protein complex to initiate a change in cell activity, activated by UDP.
45030	UTP-activated nucleotide receptor activity	F	Combining with a nucleotide and transmitting the signal to a heterotrimeric G-protein complex to initiate a change in cell activity, activated by UTP.
45031	ATP-activated adenosine receptor activity	F	Combining with adenosine and transmitting the signal to a heterotrimeric G-protein complex to initiate a change in cell activity, activated by ATP.
45032	ADP-activated adenosine receptor activity	F	Combining with adenosine and transmitting the signal to a heterotrimeric G-protein complex to initiate a change in cell activity, activated by ADP.
45033	peroxisome inheritance	P	The acquisition of peroxisomes by daughter cells from the mother cell after replication. In Saccharomyces cerevisiae, the number of peroxisomes cells is fairly constant; a subset of the organelles are targeted and segregated to the bud in a highly ordered, vectorial process. Efficient segregation of peroxisomes from mother to bud is dependent on the actin cytoskeleton, and active movement of peroxisomes along actin filaments is driven by the class V myosin motor protein, Myo2p.
45035	sensory organ precursor cell division	P	The series of four asymmetric divisions undergone by the sensory organ precursor cells to generate cells that have distinct cell fates. For example, in the external sensory organ, the precursor cells give rise to one multidendritic neuron and four additional cells (the socket, shaft, sheath cells and the external sense neuron).
45036	protein targeting to chloroplast	P	The process of directing proteins towards the chloroplast, usually using signals contained within the protein. Imported proteins are synthesized as cytosolic precursors containing N-terminal uptake-targeting sequences that direct each protein to its correct subcompartment and are subsequently cleaved.
45037	protein import into chloroplast stroma	P	The targeting and import of proteins into the chloroplast stroma. Import depends on ATP hydrolysis catalyzed by stromal chaperones. Chloroplast stromal proteins, such as the S subunit of rubisco, have a N-terminal stromal-import sequence of about 44 amino acids which is cleaved from the protein precursor after import.
45038	protein import into chloroplast thylakoid membrane	P	The import of proteins into the chloroplast thylakoid membranes. Proteins that are destined for the thylakoid lumen require two uptake-targeting sequences: the first targets the protein to the stroma, and the second targets the protein from the stroma to the thylakoid lumen. Four separate thylakoid-import systems deal with the proteins once they are in the stroma.
45039	protein import into mitochondrial inner membrane	P	The process comprising the import of proteins into the mitochondrion from outside the organelle and their insertion into the mitochondrial inner membrane. The translocase of the outer membrane complex mediates the passage of these proteins across the outer membrane, after which they are guided by either of two inner membrane translocase complexes into their final destination in the inner membrane.
45040	protein import into mitochondrial outer membrane	P	The process comprising the insertion of proteins from outside the organelle into the mitochondrial outer membrane, mediated by large outer membrane translocase complexes.
45041	protein import into mitochondrial intermembrane space	P	The import of proteins into the space between the inner and outer mitochondrial membranes.
45046	protein import into peroxisome membrane	P	The targeting of proteins into the peroxisomal membrane. The process is not well understood, but both signals and mechanism differ from those involved in peroxisomal matrix protein import.
45047	protein targeting to ER	P	The process of directing proteins towards the endoplasmic reticulum (ER) using signals contained within the protein. One common mechanism uses a 16- to 30-residue signal sequence, typically located at the N-terminus of the protein and containing positively charged amino acids followed by a continuous stretch of hydrophobic residues, which directs the ribosome to the ER membrane and initiates transport of the growing polypeptide across the ER membrane.
45048	protein insertion into ER membrane	P	The process that results in incorporation of a protein into an endoplasmic reticulum (ER) membrane. It depends on specific topogenic sequences of amino acids that ensure that a protein acquires the proper orientation during its insertion into the ER membrane.
45049	protein insertion into ER membrane by N-terminal cleaved signal sequence	P	A process of protein insertion into the endoplasmic reticulum (ER) membrane in which N-terminal cleaved signal sequences direct polypeptides to the ER.
45050	protein insertion into ER membrane by stop-transfer membrane-anchor sequence	P	A process of protein insertion into the endoplasmic reticulum (ER) membrane in which stop-transfer membrane-anchor sequences become an ER membrane spanning helix.
45051	protein insertion into ER membrane by internal uncleaved signal-anchor sequence	P	A process of protein insertion into the endoplasmic reticulum (ER) membrane in which signal anchor sequences function as both ER signal sequences and membrane anchor sequences.
45052	protein insertion into ER membrane by GPI attachment sequence	P	A process of protein insertion into the endoplasmic reticulum (ER) membrane in which proteins become anchored to the phospholipid bilayer by a covalently attached glycosylphosphatidylinositol (GPI) molecule.
45053	protein retention in Golgi apparatus	P	The retention of proteins within the Golgi apparatus. Golgi-localized carbohydrate-modifying enzymes have a short N-terminal domain that faces the cytosol, a single transmembrane alpha helix, and a large C-terminal domain that faces the Golgi lumen and that contains the catalytic site. How the membrane-spanning alpha helix in a Golgi enzyme causes its localization and prevents its movement to the plasma membrane is not known.
45054	constitutive secretory pathway	P	A process of exocytosis found in all eukaryotic cells, in which transport vesicles destined for the plasma membrane leave the trans-Golgi network in a steady stream. Upon exocytosis, the membrane proteins and lipids in these vesicles provide new components for the plasma membrane, and the soluble proteins inside the vesicles are released into the extracellular space.
45055	regulated exocytosis	P	A process of exocytosis in which soluble proteins and other substances are initially stored in secretory vesicles for later release. It is found mainly in cells that are specialized for secreting products such as hormones, neurotransmitters, or digestive enzymes rapidly on demand.
45056	transcytosis	P	The directed movement of endocytosed material through the cell and its exocytosis from the plasma membrane at the opposite side.
45057	cisternal progression	P	The process that results in the physical movement of a new cis-Golgi stack from the cis-position, nearest the endoplasmic reticulum (ER), to the trans position, farthest from the ER, successively becoming first a medial-Golgi cisterna and then a trans-Golgi cisterna.
45058	T cell selection	P	The process in which T cells that express T cell receptors that are restricted by self MHC protein complexes and tolerant to self antigens are selected for further maturation.
45059	positive thymic T cell selection	P	The process of sparing immature T cells in the thymus which react with self-MHC protein complexes with low affinity levels from apoptotic death.
45060	negative thymic T cell selection	P	The process of elimination of immature T cells in the thymus which react strongly with self-antigens.
45061	thymic T cell selection	P	The process of T cell selection that occurs in the thymus.
45062	extrathymic T cell selection	P	The process of T cell selection that occurs in extrathymic locations, often resulting T cells of distinct specificities from those selected in the thymus.
45063	T-helper 1 cell differentiation	P	The process in which a relatively unspecialized T cell acquires the specialized features of a T-helper 1 (Th1) cell. A Th1 cell is a CD4-positive, alpha-beta T cell that has the phenotype T-bet-positive and produces interferon-gamma.
45064	T-helper 2 cell differentiation	P	The process in which a relatively unspecialized T cell acquires specialized features of a T-helper 2 (Th2) cell. A Th2 cell is a CD4-positive, alpha-beta T cell that has the phenotype GATA-3-positive and produces interleukin-4.
45065	cytotoxic T cell differentiation	P	The process in which a relatively unspecialized T cell acquires specialized features of a cytotoxic T cell.
45066	regulatory T cell differentiation	P	The process in which a relatively unspecialized T cell acquires specialized features of a regulatory T cell. Regulatory T cells control or suppress immune responses through a variety of mechanisms and subsets include the CD4+CD25+ cell type as well as certain CD8+ cell types.
45067	positive extrathymic T cell selection	P	The process of sparing extrathymically maturing T cells which react with self-MHC protein complexes with low affinity levels from apoptotic death.
45068	negative extrathymic T cell selection	P	The process of elimination of extrathymically maturing T cells which react strongly with self-antigens.
45069	regulation of viral genome replication	P	Any process that modulates the frequency, rate or extent of viral genome replication.
45070	positive regulation of viral genome replication	P	Any process that activates or increases the frequency, rate or extent of viral genome replication.
45071	negative regulation of viral genome replication	P	Any process that stops, prevents, or reduces the frequency, rate or extent of viral genome replication.
45072	regulation of interferon-gamma biosynthetic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interferon-gamma.
45073	regulation of chemokine biosynthetic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of chemokines.
45074	regulation of interleukin-10 biosynthetic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-10.
45075	regulation of interleukin-12 biosynthetic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-12.
45076	regulation of interleukin-2 biosynthetic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-2.
45077	negative regulation of interferon-gamma biosynthetic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interferon-gamma.
45078	positive regulation of interferon-gamma biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interferon-gamma.
45079	negative regulation of chemokine biosynthetic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of chemokines.
45080	positive regulation of chemokine biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of chemokines.
45081	negative regulation of interleukin-10 biosynthetic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-10.
45082	positive regulation of interleukin-10 biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-10.
45083	negative regulation of interleukin-12 biosynthetic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-12.
45084	positive regulation of interleukin-12 biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-12.
45085	negative regulation of interleukin-2 biosynthetic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-2.
45086	positive regulation of interleukin-2 biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-2.
45087	innate immune response	P	Innate immune responses are defense responses mediated by germline encoded components that directly recognize components of potential pathogens.
45088	regulation of innate immune response	P	Any process that modulates the frequency, rate or extent of the innate immune response, the organism's first line of defense against infection.
45089	positive regulation of innate immune response	P	Any process that activates or increases the frequency, rate or extent of the innate immune response, the organism's first line of defense against infection.
45091	regulation of single stranded viral RNA replication via double stranded DNA intermediate	P	Any process that modulates the frequency, rate or extent of single stranded viral RNA replication via double stranded DNA intermediate.
45092	interleukin-18 receptor complex	C	A protein complex that binds interleukin-18; comprises an alpha and a beta subunit.
45093	interleukin-18 alpha subunit binding	F	Interacting selectively and non-covalently with the alpha subunit of interleukin-18. IL-18a is a component of IL-18 that is essential for IL-18 binding on the surface of T-helper 1 cells.
45094	interleukin-18 beta subunit binding	F	Interacting selectively and non-covalently with the beta subunit of interleukin-18. IL-18b is a ligand non-binding chain and is required for signaling of IL-18 that binds with IL-18a.
45095	keratin filament	C	A filament composed of acidic and basic keratins (types I and II), typically expressed in epithelial cells. The keratins are the most diverse classes of IF proteins, with a large number of keratin isoforms being expressed. Each type of epithelium always expresses a characteristic combination of type I and type II keratins.
45098	type III intermediate filament	C	A type of intermediate filament, typically made up of one or more of the proteins vimentin, desmin, glial fibrillary acidic protein (GFAP), and peripherin. Unlike the keratins, the type III proteins can form both homo- and heteropolymeric IF filaments.
45103	intermediate filament-based process	P	Any cellular process that depends upon or alters the intermediate filament cytoskeleton, that part of the cytoskeleton comprising intermediate filaments and their associated proteins.
45104	intermediate filament cytoskeleton organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising intermediate filaments and their associated proteins.
45105	intermediate filament polymerization or depolymerization	P	Assembly or disassembly of intermediate filaments by the addition or removal of component parts from a filament.
45106	intermediate filament depolymerization	P	Disassembly of intermediate filaments by the removal of component monomers from a filament.
45107	intermediate filament polymerization	P	Assembly of intermediate filaments by the addition of component monomers to a filament. Polymerization of intermediate filament proteins results from interactions among several distinct binding sites on the constituent proteins. Nuclear lamin head-to-tail polymers arise from one such interaction. Deletion analysis localized the binding sites to the ends of the rod domain that are highly conserved among all intermediate filament proteins. Data indicate that one type of interaction in intermediate filament protein polymerization is the longitudinal binding of dimers via the conserved end segments of the coiled-coil rod domain.
45108	regulation of intermediate filament polymerization or depolymerization	P	Any process that modulates the frequency, rate or extent of the assembly or disassembly of intermediate filaments by the addition or removal of monomers from a filament; this usually occurs through the opposing action of kinases and phosphatases.
45109	intermediate filament organization	P	Control of the spatial distribution of intermediate filaments; includes organizing filaments into meshworks, bundles, or other structures, as by cross-linking.
45110	intermediate filament bundle assembly	P	The formation of the bundles of intermediate filaments. Intermediate filament-associated proteins (IFAPs) cross-link intermediate filaments with one another, forming a bundle or a network, and with other cell structures, including the plasma membrane. The organization of intermediate filaments and their supportive function in various cells types depends in large part on their linkage to other cell structures via IFAPs.
45111	intermediate filament cytoskeleton	C	Cytoskeletal structure made from intermediate filaments, typically organized in the cytosol as an extended system that stretches from the nuclear envelope to the plasma membrane. Some intermediate filaments run parallel to the cell surface, while others traverse the cytosol; together they form an internal framework that helps support the shape and resilience of the cell.
45112	integrin biosynthetic process	P	The chemical reactions and pathways resulting in the formation of integrins, a large family of transmembrane proteins that act as receptors for cell-adhesion molecules.
45113	regulation of integrin biosynthetic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of integrins.
45114	beta 2 integrin biosynthetic process	P	The chemical reactions and pathways resulting in the formation of beta 2 integrins, a subfamily of integrins which contain the beta 2 subunit.
45115	regulation of beta 2 integrin biosynthetic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of beta 2 integrins.
45116	protein neddylation	P	Covalent attachment of the ubiquitin-like protein NEDD8 (RUB1) to another protein.
45117	azole transport	P	The directed movement of azoles, heterocyclic compounds found in many biologically important substances, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
45118	azole transporter activity	F	Enables the directed movement of azoles, heterocyclic compound found in many biologically important substances, into, out of or within a cell, or between cells.
45119	azole:proton antiporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: H+(out) + azole(in) = H+(in) + azole(out). Azoles are heterocyclic compounds found in many biologically important substances.
45120	pronucleus	C	The nucleus of either the ovum or the spermatozoon following fertilization. Thus, in the fertilized ovum, there are two pronuclei, one originating from the ovum, the other from the spermatozoon that brought about fertilization; they approach each other, but do not fuse until just before the first cleavage, when each pronucleus loses its membrane to release its contents.
45121	membrane raft	C	Any of the small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes. Small rafts can sometimes be stabilized to form larger platforms through protein-protein and protein-lipid interactions.
45122	aflatoxin biosynthetic process	P	The chemical reactions and pathways resulting in the formation of aflatoxin, a fungal metabolite found as a contaminant in moldy grains that induces liver cancer. Aflatoxin induces a G to T transversion at codon 249 of p53, leading to its inactivation. Aflatoxin is converted to a chemical carcinogen by P450.
45123	cellular extravasation	P	The migration of a leukocyte from the blood vessels into the surrounding tissue.
45124	regulation of bone resorption	P	Any process that modulates the frequency, rate or extent of bone tissue loss (resorption).
45125	bioactive lipid receptor activity	F	Combining with a bioactive lipid and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex. A bioactive lipid is a lipid for which changes in lipid levels result in functional consequences in a variety of cellular processes.
45127	N-acetylglucosamine kinase activity	F	Catalysis of the reaction: N-acetyl-D-glucosamine + ATP = N-acetyl-D-glucosamine 6-phosphate + ADP + 2 H(+).
45128	negative regulation of reciprocal meiotic recombination	P	Any process that decreases the frequency, rate or extent of recombination during meiosis. Reciprocal meiotic recombination is the cell cycle process in which double strand breaks are formed and repaired through a double Holliday junction intermediate.
45129	NAD-independent histone deacetylase activity	F	Catalysis of the reaction: histone N6-acetyl-L-lysine + H2O = histone L-lysine + acetate. This reaction does not require the presence of NAD, and represents the removal of an acetyl group from a histone.
45130	keratan sulfotransferase activity	F	Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + keratan = adenosine 3',5'-bisphosphate + keratan 6'-sulfate.
45131	pre-mRNA branch point binding	F	Interacting selectively and non-covalently with a pre-mRNA branch point sequence, located upstream of the 3' splice site.
45132	meiotic chromosome segregation	P	The process in which genetic material, in the form of chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets during M phase of the meiotic cell cycle.
45133	2,3-dihydroxybenzoate 3,4-dioxygenase activity	F	Catalysis of the reaction: 2,3-dihydroxybenzoate + O(2) = 2-hydroxy-3-(3-oxoprop-1-enyl)but-2-enedioate + H(+).
45134	uridine-diphosphatase activity	F	Catalysis of the reaction: UDP + H2O = UMP + phosphate.
45135	poly(beta-D-mannuronate) lyase activity	F	Catalysis of the reaction: polysaccharides containing beta-D-mannuronate residues = oligosaccharides with 4-deoxy-alpha-L-erythro-hex-4-enopyranuronosyl end. This reaction is the eliminative cleavage of polysaccharides containing beta-D-mannuronate residues to give oligosaccharides with 4-deoxy-alpha-L-erythro-hex-4-enopyranuronosyl groups at their ends.
45136	development of secondary sexual characteristics	P	The process whose specific outcome is the progression of the secondary sexual characteristics over time, from their formation to the mature structures. In humans, these include growth of axillary, chest, and pubic hair, voice changes, testicular/penile enlargement, breast development and menstrual periods. Development occurs in response to sex hormone secretion.
45137	development of primary sexual characteristics	P	The process whose specific outcome is the progression of the primary sexual characteristics over time, from their formation to the mature structures. The primary sexual characteristics are the testes in males and the ovaries in females and they develop in response to sex hormone secretion.
45138	nematode male tail tip morphogenesis	P	The process in which the anatomical structure of the adult male tail tip is generated and organized. In some species of rhabitid nematodes, the male tail tip undergoes a morphological change such that the most posterior hypodermal cells in the tail (hyp8-11 in C. elegans) fuse and retract anteriorly, changing the shape of the tail from a pointed, tapered cone, or spike, to a rounded, blunt dome.
45140	inositol phosphoceramide synthase activity	F	Catalysis of the reaction: phytoceramide + inositol phosphate = inositol phosphoceramide.
45141	meiotic telomere clustering	P	The cell cycle process in which the dynamic reorganization of telomeres occurs in early meiotic prophase, during which meiotic chromosome ends are gathered in a bouquet arrangement at the inner surface of the nuclear envelope proximal to the spindle pole body. This plays an important role in progression through meiosis and precedes synapsis.
45142	triplex DNA binding	F	Interacting selectively and non-covalently with a DNA triple helix. The formation of triple helical DNA has been evoked in several cellular processes including transcription, replication, and recombination.
45143	homologous chromosome segregation	P	The cell cycle process in which replicated homologous chromosomes are organized and then physically separated and apportioned to two sets during the first division of the meiotic cell cycle. Each replicated chromosome, composed of two sister chromatids, aligns at the cell equator, paired with its homologous partner; this pairing off, referred to as synapsis, permits genetic recombination. One homolog (both sister chromatids) of each morphologic type goes into each of the resulting chromosome sets.
45144	meiotic sister chromatid segregation	P	The cell cycle process in which sister chromatids are organized and then physically separated and randomly apportioned to two sets during the second division of the meiotic cell cycle.
45145	single-stranded DNA 5'-3' exodeoxyribonuclease activity	F	Catalysis of the sequential cleavage of nucleotides (such as mononucleotides or dinucleotides) from a free 5' terminus of a single-stranded DNA molecule.
45146	initiation of acetate catabolic process by acetate	P	The activation, by acetate, of the chemical reactions and pathways resulting in the breakdown of acetate.
45147	regulation of initiation of acetate catabolic process by acetate	P	Any process that modulates the activation, by acetate, of the chemical reactions and pathways resulting in the breakdown of acetate.
45148	tripeptide aminopeptidase activity	F	Catalysis of the release of the N-terminal residue from a tripeptide.
45149	acetoin metabolic process	P	The chemical reactions and pathways involving acetoin, 3-hydroxy-2-butanone, often as part of a fermentation pathway or for use as a carbon source.
45150	acetoin catabolic process	P	The chemical reactions and pathways resulting in the breakdown of acetoin, 3-hydroxy-2-butanone.
45151	acetoin biosynthetic process	P	The chemical reactions and pathways resulting in the formation of acetoin, 3-hydroxy-2-butanone.
45152	antisigma factor binding	F	Interacting selectively and non-covalently with an antisigma factor, a factor which inhibits the ability of the sigma factor to function as a transcriptional initiator.
45153	electron transporter, transferring electrons within CoQH2-cytochrome c reductase complex activity	F	Enables the directed movement of electrons within the CoQH2-cytochrome c reductase complex.
45154	electron transporter, transferring electrons within cytochrome c oxidase complex activity	F	Enables the directed movement of electrons within the cytochrome c oxidase complex.
45155	electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity	F	Enables the directed movement of electrons from the CoQH2-cytochrome c reductase complex and the cytochrome c oxidase complex.
45156	electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity	F	Enables the directed movement of electrons within the cyclic electron transport pathway of photosynthesis.
45157	electron transporter, transferring electrons within the noncyclic electron transport pathway of photosynthesis activity	F	Enables the directed movement of electrons within the noncyclic electron transport pathway of photosynthesis.
45158	electron transporter, transferring electrons within cytochrome b6/f complex of photosystem II activity	F	Enables the directed movement of electrons within the cytochrome b6/f complex of photosystem II.
45159	myosin II binding	F	Interacting selectively and non-covalently with a class II myosin, any member of the class of 'conventional' double-headed myosins that includes muscle myosin.
45160	myosin I complex	C	A myosin complex containing a class I myosin heavy chain and associated light chains; myosin I heavy chains are single-headed, possess tails of various lengths, and do not self-associate into bipolar filaments; myosin I complexes are involved in diverse processes related to membrane traffic and cell movement.
45161	neuronal ion channel clustering	P	The process in which voltage-gated ion channels become localized to distinct subcellular domains in the neuron. Specific targeting, clustering, and maintenance of these channels in their respective domains are essential to achieve high conduction velocities of action potential propagation.
45162	clustering of voltage-gated sodium channels	P	The process in which voltage-gated sodium channels become localized together in high densities. In animals, nodes of Ranvier differ dramatically from internodal axonal regions in very high densities of voltage-dependent sodium (Nav) channels responsible for the rapid, inward ionic currents that produce membrane depolarization.
45163	clustering of voltage-gated potassium channels	P	The process in which voltage-gated potassium channels become localized together in high densities. In animals, voltage-gated potassium (Kv) channels are clustered beneath the myelin sheath in regions immediately adjacent to paranodes, called juxtaparanodes, and along the inner mesaxon within the internode.
45165	cell fate commitment	P	The commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field.
45167	asymmetric protein localization involved in cell fate determination	P	Any process in which a protein is transported to, or maintained in, a specific asymmetric distribution, resulting in the formation of daughter cells of different types.
45168	cell-cell signaling involved in cell fate commitment	P	Signaling at long or short range between cells that results in the commitment of a cell to a certain fate.
45169	fusome	C	A large intracellular spectrin-rich structure that has been found in insect germline cells and mammalian hematopoietic cells. The fusome is an elongated, branched structure, formed from the spherical spectrosome organelle.
45170	spectrosome	C	A germline specific spherical organelle, rich in membrane skeletal proteins. Precursor to the fusome.
45171	intercellular bridge	C	A direct connection between the cytoplasm of two cells that is formed following the completion of cleavage furrow ingression during cell division. They are usually present only briefly prior to completion of cytokinesis. However, in some cases, such as the bridges between germ cells during their development, they become stabilised.
45172	germline ring canal	C	Germline specific intercellular bridge. During cyst formation in insects, ring canals interconnect the cells of the cyst, facilitating the passage of cytoplasmic components between cells.
45173	O-sialoglycoprotein catabolic process	P	The chemical reactions and pathways resulting in the breakdown of O-sialoglycoproteins, glycoproteins which contain sialic acid as one of their carbohydrates. They are often found on or in the cell or tissue membranes and participate in a variety of biological activities.
45174	glutathione dehydrogenase (ascorbate) activity	F	Catalysis of the reaction: dehydroascorbate + 2 glutathione = L-ascorbate + glutathione disulfide.
45175	basal protein localization	P	Any process in which a protein is transported to, or maintained in, basal regions of the cell.
45176	apical protein localization	P	Any process in which a protein is transported to, or maintained in, apical regions of the cell.
45177	apical part of cell	C	The region of a polarized cell that forms a tip or is distal to a base. For example, in a polarized epithelial cell, the apical region has an exposed surface and lies opposite to the basal lamina that separates the epithelium from other tissue.
45178	basal part of cell	C	The region of a cell situated near the base. For example, in a polarized epithelial cell, the basal surface rests on the basal lamina that separates the epithelium from other tissue.
45179	apical cortex	C	The region that lies just beneath the plasma membrane on the apical edge of a cell.
45180	basal cortex	C	The region that lies just beneath the plasma membrane on the basal edge of a cell.
45181	glutamate synthase activity, NAD(P)H as acceptor	F	Catalysis of the reaction: 2 L-glutamate + NAD(P)+ = L-glutamine + 2-oxoglutarate + NAD(P)H + H+.
45182	translation regulator activity	F	Any molecular function involved in the initiation, activation, perpetuation, repression or termination of polypeptide synthesis at the ribosome.
45183	translation factor activity, non-nucleic acid binding	F	A translation regulator activity that does not involve binding to nucleic acids.
45184	establishment of protein localization	P	The directed movement of a protein to a specific location.
45185	maintenance of protein location	P	Any process in which a protein is maintained in a location and prevented from moving elsewhere. These include sequestration, stabilization to prevent transport elsewhere and the active retrieval of proteins that do move away.
45186	zonula adherens assembly	P	Assembly of the zonula adherens, a cell-cell adherens junction which forms a continuous belt near the apex of epithelial cells.
45187	regulation of circadian sleep/wake cycle, sleep	P	Any process that modulates the frequency, rate or extent of sleep; a readily reversible state of reduced awareness and metabolic activity that occurs periodically in many animals.
45188	regulation of circadian sleep/wake cycle, non-REM sleep	P	Any process that modulates the frequency, rate or extent of non-rapid eye movement sleep.
45189	connective tissue growth factor biosynthetic process	P	The chemical reactions and pathways resulting in the formation of CTGF, produced by human umbilical vein endothelial cells and by skin fibroblasts after activation with TGF-beta.
45190	isotype switching	P	The switching of activated B cells from IgM biosynthesis to biosynthesis of other isotypes of immunoglobulin, accomplished through a recombination process involving an intrachromosomal deletion involving switch regions that reside 5' of each constant region gene segment in the immunoglobulin heavy chain locus.
45191	regulation of isotype switching	P	Any process that modulates the frequency, rate or extent of isotype switching.
45196	establishment or maintenance of neuroblast polarity	P	Any cellular process that results in the specification, formation or maintenance of the apicobasal polarity of a neuroblast cell, a progenitor of the central nervous system.
45197	establishment or maintenance of epithelial cell apical/basal polarity	P	Any cellular process that results in the specification, formation or maintenance of the apicobasal polarity of an epithelial cell.
45198	establishment of epithelial cell apical/basal polarity	P	The specification and formation of the apicobasal polarity of an epithelial cell.
45199	maintenance of epithelial cell apical/basal polarity	P	The maintenance of the apicobasal polarity of an epithelial cell.
45200	establishment of neuroblast polarity	P	The specification and formation of the apicobasal polarity of a neuroblast cell, a progenitor of the central nervous system.
45201	maintenance of neuroblast polarity	P	The maintenance of the apicobasal polarity of a neuroblast cell, a progenitor of the central nervous system.
45202	synapse	C	The junction between a nerve fiber of one neuron and another neuron, muscle fiber or glial cell. As the nerve fiber approaches the synapse it enlarges into a specialized structure, the presynaptic nerve ending, which contains mitochondria and synaptic vesicles. At the tip of the nerve ending is the presynaptic membrane; facing it, and separated from it by a minute cleft (the synaptic cleft) is a specialized area of membrane on the receiving cell, known as the postsynaptic membrane. In response to the arrival of nerve impulses, the presynaptic nerve ending secretes molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane.
45203	integral component of cell outer membrane	C	The component of the cell outer membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
45204	MAPK export from nucleus	P	The directed movement of a MAP kinase from the nucleus to the cytoplasm.
45208	MAPK phosphatase export from nucleus	P	The directed movement of a MAPK phosphatase from the nucleus to the cytoplasm.
45209	MAPK phosphatase export from nucleus, leptomycin B sensitive	P	Leptomycin B-sensitive movement of a MAPK phosphatase from the nucleus to the cytoplasm.
45210	FasL biosynthetic process	P	The chemical reactions and pathways resulting in the formation of fas ligand (FasL or CD95L), an antigen originally found to be expressed on the cell surface of activated human T-lymphocytes and B-lymphocytes and a variety of malignant human lymphoid cell lines.
45211	postsynaptic membrane	C	A specialized area of membrane facing the presynaptic membrane on the tip of the nerve ending and separated from it by a minute cleft (the synaptic cleft). Neurotransmitters cross the synaptic cleft and transmit the signal to the postsynaptic membrane.
45212	neurotransmitter receptor biosynthetic process	P	The chemical reactions and pathways resulting in the formation of neurotransmitter receptors.
45213	neurotransmitter receptor metabolic process	P	The chemical reactions and pathways involving neurotransmitter receptors.
45214	sarcomere organization	P	The myofibril assembly process that results in the organization of muscle actomyosin into sarcomeres. The sarcomere is the repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs.
45216	cell-cell junction organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a cell-cell junction. A cell-cell junction is a specialized region of connection between two cells.
45217	cell-cell junction maintenance	P	The maintenance of junctions between cells.
45218	zonula adherens maintenance	P	Maintaining the zonula adherens junction, the cell-cell adherens junction formed near the apex of epithelial cells.
45219	regulation of FasL biosynthetic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of FasL.
45220	positive regulation of FasL biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of FasL.
45221	negative regulation of FasL biosynthetic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of FasL.
45222	CD4 biosynthetic process	P	The chemical reactions and pathways resulting in the formation of CD4, a CD marker that occurs on T-helper cells and is involved in MHC class II restricted interactions.
45223	regulation of CD4 biosynthetic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of CD4.
45224	positive regulation of CD4 biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of CD4.
45225	negative regulation of CD4 biosynthetic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of CD4.
45226	extracellular polysaccharide biosynthetic process	P	The chemical reactions and pathways resulting in the formation of polysaccharides used in extracellular structures.
45227	capsule polysaccharide biosynthetic process	P	The chemical reactions and pathways resulting in the formation of polysaccharides that make up the capsule, a protective structure surrounding some species of bacteria and fungi.
45228	slime layer polysaccharide biosynthetic process	P	The chemical reactions and pathways resulting in the formation of polysaccharides in the slime layer, a diffused layer of polysaccharide exterior to the bacterial cell wall.
45229	external encapsulating structure organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of external structures that lie outside the plasma membrane and surround the entire cell.
45230	capsule organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the capsule, a protective structure surrounding some species of bacteria and fungi.
45231	slime layer organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a slime layer. A slime layer is an easily removed, diffuse, unorganized layer of extracellular material that surrounds a cell.
45232	S-layer organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an S-layer enveloping the cell. The S-layer is a crystalline protein layer surrounding some bacteria.
45234	protein palmitoleylation	P	The covalent attachment of a palmitoleyl group to a protein.
45236	CXCR chemokine receptor binding	F	Interacting selectively and non-covalently with a chemokine receptor in the CXCR family.
45237	CXCR1 chemokine receptor binding	F	Interacting selectively and non-covalently with the CXCR1 chemokine receptor.
45238	CXCR2 chemokine receptor binding	F	Interacting selectively and non-covalently with the CXCR2 chemokine receptor.
45239	tricarboxylic acid cycle enzyme complex	C	Any of the heteromeric enzymes that act in the TCA cycle.
45240	dihydrolipoyl dehydrogenase complex	C	A protein complex that possesses alpha-ketoglutarate dehydrogenase activity.
45241	cytosolic alpha-ketoglutarate dehydrogenase complex	C	Cytosolic complex that possesses alpha-ketoglutarate dehydrogenase activity.
45242	isocitrate dehydrogenase complex (NAD+)	C	Complex that possesses isocitrate dehydrogenase (NAD+) activity.
45243	cytosolic isocitrate dehydrogenase complex (NAD+)	C	Cytosolic complex that possesses isocitrate dehydrogenase (NAD+) activity.
45244	succinate-CoA ligase complex (GDP-forming)	C	A heterodimeric enzyme complex, usually composed of an alpha and beta chain. Functions in the TCA cycle, hydrolyzing succinyl-CoA into succinate and CoA, thereby forming GTP.
45246	cytosolic tricarboxylic acid cycle enzyme complex	C	Any of the heteromeric enzymes, located in the cytosol, that act in the tricarboxylic acid (TCA) cycle.
45247	cytosolic electron transfer flavoprotein complex	C	A protein complex located in the cytosol containing flavin adenine dinucleotide (FAD) that, together with an acyl-CoA dehydrogenase, forms a system that oxidizes an acyl-CoA molecule and reduces ubiquinone and other acceptors.
45248	cytosolic oxoglutarate dehydrogenase complex	C	A cytosolic complex of multiple copies of three enzymatic components: oxoglutarate dehydrogenase (lipoamide); EC:1.2.4.2 (E1), dihydrolipoamide S-succinyltransferase; EC:2.3.1.61 (E2) and dihydrolipoamide dehydrogenase; EC:1.8.1.4 (E3); catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and carbon dioxide (CO2).
45249	cytosol pyruvate dehydrogenase (lipoamide) phosphatase complex	C	A cytosolic complex of a regulatory and catalytic subunit that catalyzes the dephosphorylation and concomitant reactivation of the alpha subunit of the E1 component of the pyruvate dehydrogenase complex.
45250	cytosolic pyruvate dehydrogenase complex	C	Complex that carries out the oxidative decarboxylation of pyruvate to form acetyl-CoA; comprises subunits possessing three catalytic activities: pyruvate dehydrogenase (E1), dihydrolipoamide S-acetyltransferase (E2), and dihydrolipoamide dehydrogenase (E3). Usually contains fewer subunits than its eukaryotic counterpart; for example, the E. coli complex contains 12 E1 dimers, 8 E2 trimers, and 6 E3 dimers arranged in highly symmetric cubic order.
45251	electron transfer flavoprotein complex	C	A protein complex containing flavin adenine dinucleotide (FAD) and acyl-CoA dehydrogenase, which form a system that oxidizes an acyl-CoA molecule and reduces ubiquinone and other acceptors in an electron transport system.
45252	oxoglutarate dehydrogenase complex	C	A complex of multiple copies of three enzymatic components: oxoglutarate dehydrogenase (lipoamide); EC:1.2.4.2 (E1), dihydrolipoamide S-succinyltransferase; EC:2.3.1.61 (E2) and dihydrolipoamide dehydrogenase; EC:1.8.1.4 (E3); catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and carbon dioxide (CO2).
45253	pyruvate dehydrogenase (lipoamide) phosphatase complex	C	A complex of a regulatory and catalytic subunit that catalyzes the dephosphorylation and concomitant reactivation of the alpha subunit of the E1 component of the pyruvate dehydrogenase complex.
45254	pyruvate dehydrogenase complex	C	Complex that carries out the oxidative decarboxylation of pyruvate to form acetyl-CoA; comprises subunits possessing three catalytic activities: pyruvate dehydrogenase (E1), dihydrolipoamide S-acetyltransferase (E2), and dihydrolipoamide dehydrogenase (E3).
45257	succinate dehydrogenase complex (ubiquinone)	C	The enzyme that catalyzes the oxidation of succinate and ubiquinone to fumarate and ubiquinol; involved in aerobic respiration, repressed in anaerobic respiration.
45258	plasma membrane succinate dehydrogenase complex (ubiquinone)	C	The enzyme, located in the plasma membrane, that catalyzes the oxidation of succinate and ubiquinone to fumarate and ubiquinol; involved in aerobic respiration, repressed in anaerobic respiration.
45259	proton-transporting ATP synthase complex	C	A proton-transporting two-sector ATPase complex that catalyzes the phosphorylation of ADP to ATP during oxidative phosphorylation. The complex comprises a membrane sector (F0) that carries out proton transport and a cytoplasmic compartment sector (F1) that catalyzes ATP synthesis by a rotational mechanism; the extramembrane sector (containing 3 a and 3 b subunits) is connected via the d-subunit to the membrane sector by several smaller subunits. Within this complex, the g and e subunits and the 9-12 c subunits rotate by consecutive 120 degree angles and perform parts of ATP synthesis. This movement is driven by the hydrogen ion electrochemical potential gradient.
45260	plasma membrane proton-transporting ATP synthase complex	C	A proton-transporting ATP synthase complex found in the plasma membrane. Examples of this component are found in Bacterial species.
45261	proton-transporting ATP synthase complex, catalytic core F(1)	C	The sector of a hydrogen-transporting ATP synthase complex in which the catalytic activity resides; it comprises the catalytic core and central stalk, and is peripherally associated with a membrane, such as the plasma membrane or the mitochondrial inner membrane, when the entire ATP synthase is assembled.
45262	plasma membrane proton-transporting ATP synthase complex, catalytic core F(1)	C	The catalytic sector of the plasma membrane hydrogen-transporting ATP synthase; it comprises the catalytic core and central stalk, and is peripherally associated with the plasma membrane when the entire ATP synthase is assembled. Examples of this component are found in Bacterial species.
45263	proton-transporting ATP synthase complex, coupling factor F(o)	C	All non-F1 subunits of a hydrogen-transporting ATP synthase, including integral and peripheral membrane proteins.
45264	plasma membrane proton-transporting ATP synthase complex, coupling factor F(o)	C	All non-F1 subunits of the plasma membrane hydrogen-transporting ATP synthase, including integral and peripheral plasma membrane proteins.
45265	proton-transporting ATP synthase, stator stalk	C	One of two stalks that connect the catalytic core of the hydrogen-transporting ATP synthase to the membrane-associated Fo proteins; is thought to prevent futile rotation of the catalytic core.
45266	plasma membrane proton-transporting ATP synthase, stator stalk	C	One of two stalks that connect the catalytic core of the hydrogen-transporting ATP synthase to the plasma membrane-associated F0 proteins; is thought to prevent futile rotation of the catalytic core. Examples of this component are found in Bacterial species.
45267	proton-transporting ATP synthase, catalytic core	C	The hexamer that possesses the catalytic activity of the mitochondrial hydrogen-transporting ATP synthase.
45268	plasma membrane proton-transporting ATP synthase, catalytic core	C	The hexamer that possesses the catalytic activity of the plasma membrane hydrogen-transporting ATP synthase. Examples of this component are found in Bacterial species.
45269	proton-transporting ATP synthase, central stalk	C	One of two stalks that connect the catalytic core of the hydrogen-transporting ATP synthase to the membrane-associated Fo proteins; rotates within the catalytic core during catalysis.
45270	plasma membrane proton-transporting ATP synthase, central stalk	C	One of two stalks that connect the catalytic core of the hydrogen-transporting ATP synthase to the plasma membrane-associated Fo proteins; rotates within the catalytic core during catalysis. Examples of this component are found in Bacterial species.
45271	respiratory chain complex I	C	Respiratory chain complex I is an enzyme of the respiratory chain. It consists of several polypeptide chains and is L-shaped, with a horizontal arm lying in the membrane and a vertical arm that projects into the matrix. The electrons of NADH enter the chain at this complex.
45272	plasma membrane respiratory chain complex I	C	A subcomplex of the respiratory chain located in the plasma membrane. It contains about 25 different polypeptide subunits, including NADH dehydrogenase (ubiquinone), flavin mononucleotide and several different iron-sulfur clusters containing non-heme iron. The iron undergoes oxidation-reduction between Fe(II) and Fe(III), and catalyzes proton translocation linked to the oxidation of NADH by ubiquinone. Examples of this component are found in bacterial species.
45273	respiratory chain complex II	C	A part of the respiratory chain, containing the four polypeptide subunits of succinate dehydrogenase, flavin-adenine dinucleotide and iron-sulfur. Catalyzes the oxidation of succinate by ubiquinone. Connects the TCA cycle with the respiratory chain.
45274	plasma membrane respiratory chain complex II	C	A part of the respiratory chain located in the plasma membrane, containing the four polypeptide subunits of succinate dehydrogenase, flavin-adenine dinucleotide and iron-sulfur. Catalyzes the oxidation of succinate by ubiquinone. Connects the TCA cycle with the respiratory chain. Examples of this component are found in bacterial species.
45275	respiratory chain complex III	C	A protein complex that transfers electrons from ubiquinol to cytochrome c and translocates two protons across a membrane. The complex contains a core structure of three catalytic subunits: cytochrome b, the Rieske iron sulfur protein (ISP), and cytochrome c1, which are arranged in an integral membrane-bound dimeric complex; additional subunits are present, and vary among different species.
45276	plasma membrane respiratory chain complex III	C	A part of the respiratory chain located in the plasma membrane, containing about 10 polypeptide subunits including four redox centers: cytochrome b/b6, cytochrome c1 and an 2Fe-2S cluster. Catalyzes the oxidation of ubiquinol by oxidized cytochrome c1. Examples of this component are found in bacterial species.
45277	respiratory chain complex IV	C	A part of the respiratory chain, containing the 13 polypeptide subunits of cytochrome c oxidase, including cytochrome a and cytochrome a3. Catalyzes the oxidation of reduced cytochrome c by dioxygen (O2).
45278	plasma membrane respiratory chain complex IV	C	A part of the respiratory chain located in the plasma membrane, containing the 13 polypeptide subunits of cytochrome c oxidase, including cytochrome a and cytochrome a3. Catalyzes the oxidation of reduced cytochrome c by dioxygen (O2). Examples of this component are found in bacterial species.
45281	succinate dehydrogenase complex	C	A multimeric complex which consists of flavoprotein (subunit A; InterPro:IPR003952), iron-sulfur protein (subunit B) and membrane-bound cytochrome b560 (subunit C; InterPro:IPR000701). In some Archaea, the membrane-bound subunits (C or C and D) do not necessarily contain heme. Membrane-bound subunits can bind or react with quinones.
45282	plasma membrane succinate dehydrogenase complex	C	A multimeric complex which consists of flavoprotein (subunit A; InterPro:IPR003952), iron-sulfur protein (subunit B) and membrane-bound cytochrome b560 (subunit C; InterPro:IPR000701). In some Archaea, the membrane-bound subunits (C or C and D) do not necessarily contain heme. Membrane-bound subunits can bind/react with quinones. Examples of this component are found in Bacterial species.
45283	fumarate reductase complex	C	A membrane-bound flavoenzyme complex consisting of four subunits, A, B, C, and D. A and B comprise the membrane-extrinsic catalytic domain and C (InterPro:IPR003510; InterPro:IPR004224) and D (InterPro:IPR003418) link the catalytic centers to the electron-transport chain. This family consists of the 13 kDa hydrophobic subunit D. This component may be required to anchor the catalytic components of the fumarate reductase complex to the cytoplasmic membrane. Fumarate reductase couples the reduction of fumarate to succinate to the oxidation of quinol to quinone, in a reaction opposite to that catalyzed by the related complex II of the respiratory chain (succinate dehydrogenase-(ubiquinone)).
45284	plasma membrane fumarate reductase complex	C	A membrane-bound flavoenzyme complex consisting of four subunits, A, B, C, and D. A and B comprise the membrane-extrinsic catalytic domain and C (InterPro:IPR003510; InterPro:IPR00224) and D (InterPro:IPR003418) link the catalytic centers to the electron-transport chain. In some species, the complex has only three subunits, and in these cases, there is only one membrane anchor instead of two. This family consists of the 13 kDa hydrophobic subunit D. This component may be required to anchor the catalytic components of the fumarate reductase complex to the cytoplasmic membrane. Fumarate reductase couples the reduction of fumarate to succinate to the oxidation of quinol to quinone, in a reaction opposite to that catalyzed by the related complex II of the respiratory chain (succinate dehydrogenase-(ubiquinone)). Examples of this component are found in bacterial species.
45289	luciferin monooxygenase activity	F	Catalysis of the generalized reaction: luciferin + O2 = oxidized luciferin + CO2 + light. There may be additional substrates and reactants involved in the reaction. The reaction results in light emission as luciferin returns to the ground state after enzymatic oxidation.
45290	D-arabinose 1-dehydrogenase [NAD(P)+] activity	F	Catalysis of the reaction: D-arabinose + NAD(P)+ = D-arabinono-1,4-lactone + NAD(P)H + H+.
45291	mRNA trans splicing, SL addition	P	The joining together of two independently transcribed RNAs, where the one that provides the 5' portion of the final mRNA is from a splice leader RNA (SL-RNA). The SL-RNA, or mini-exon donor sequence, is added to the 5'-end of the acceptor RNA molecule which provides the mRNA body.
45292	mRNA cis splicing, via spliceosome	P	The joining together, after removal of an intervening sequence composed of one or more introns, of two segments of the same RNA molecule via spliceosomal catalysis to produce an mRNA composed only of exon sequences that all came from the same primary transcript.
45293	mRNA editing complex	C	A protein complex that posttranscriptionally catalyzes insertion, deletion or substitution of nucleotides at multiple sites within nascent mRNA transcripts to produce mature mRNAs in eukaryotes.
45294	alpha-catenin binding	F	Interacting selectively and non-covalently with the alpha subunit of the catenin complex.
45295	gamma-catenin binding	F	Interacting selectively and non-covalently with the gamma subunit of the catenin complex.
45296	cadherin binding	F	Interacting selectively and non-covalently with cadherin, a type I membrane protein involved in cell adhesion.
45297	post-mating behavior	P	The specific behavior of an organism following mating.
45298	tubulin complex	C	A heterodimer of tubulins alpha and beta that constitutes the protomer for microtubule assembly.
45299	otolith mineralization	P	The precipitation of specific crystal forms of calcium carbonate with extracellular matrix proteins in the otolith organs of the vertebrate inner ear.
45300	acyl-[acyl-carrier-protein] desaturase activity	F	Catalysis of the reaction: stearoyl-[acyl-carrier protein] + reduced acceptor + O2 = oleoyl-[acyl-carrier protein] + acceptor + H2O. The enzyme requires ferredoxin.
45301	tRNA-(2-methylthio-N-6-(cis-hydroxy)isopentenyl adenosine)-hydroxylase activity	F	Catalysis of the reaction: tRNA-(2-methylthio-N-6-isopentenyl adenosine) = tRNA-(2-methylthio-N-6-(cis-hydroxy)isopentenyl adenosine) + O2. 2-methylthio-N-6-isopentenyl adenosine is also known as ms2i6A; 2-methylthio-N-6-(cis-hydroxy)isopentenyl adenosine is also known as ms2io6A and 2-methylthio-cis-ribozeatin.
45302	choloylglycine hydrolase activity	F	Catalysis of the reaction: 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholan-24-oylglycine + H2O = 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholanate + glycine.
45303	diaminobutyrate-2-oxoglutarate transaminase activity	F	Catalysis of the reaction: 2-oxoglutarate + L-2,4-diaminobutyrate = L-aspartate 4-semialdehyde + L-glutamate.
45304	regulation of establishment of competence for transformation	P	Any process that modulates the frequency, rate or extent of the process in which a cell becomes able to take up and incorporate extracellular DNA into its genome.
45309	protein phosphorylated amino acid binding	F	Interacting selectively and non-covalently with a phosphorylated amino acid residue within a protein.
45311	invasive growth in response to pheromone	P	The growth of colonies in filamentous chains of cells as a result of a pheromone stimulus.
45312	nor-spermidine biosynthetic process	P	The chemical reactions and pathways resulting in the formation of nor-spermidine, a compound related to spermidine, N-(3-aminopropyl)-1,4-diaminobutane.
45313	rhabdomere membrane biogenesis	P	A process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a rhabdomere membrane.
45314	regulation of compound eye photoreceptor development	P	Any process that modulates the frequency, rate or extent of compound eye photoreceptor development.
45315	positive regulation of compound eye photoreceptor development	P	Any process that activates or increases the frequency, rate or extent of compound eye photoreceptor development.
45316	negative regulation of compound eye photoreceptor development	P	Any process that stops, prevents, or reduces the frequency, rate or extent of compound eye photoreceptor development.
45317	equator specification	P	The formation and development of the equator that forms the boundary between the photoreceptors in the dorsal sector of the eye and those in the ventral sector, dividing the eye into dorsal and ventral halves.
45320	chloroplast proton-transporting ATP synthase complex	C	A proton-transporting ATP synthase complex found in the chloroplast thylakoid membrane; it catalyzes the phosphorylation of ADP to ATP during photo-phosphorylation.
45321	leukocyte activation	P	A change in morphology and behavior of a leukocyte resulting from exposure to a specific antigen, mitogen, cytokine, cellular ligand, or soluble factor.
45322	unmethylated CpG binding	F	Interacting selectively and non-covalently with unmethylated CpG motifs. Unmethylated CpG dinucleotides are often associated with gene promoters.
45323	interleukin-1 receptor complex	C	A protein complex that binds interleukin-1; comprises an alpha and a beta subunit.
45324	late endosome to vacuole transport	P	The directed movement of substances from late endosomes to the vacuole. In yeast, after transport to the prevacuolar compartment, endocytic content is delivered to the late endosome and on to the vacuole. This pathway is analogous to endosome to lysosome transport.
45325	peptidyl-tryptophan hydroxylation	P	The hydroxylation of peptidyl-tryptophan, to form peptidyl-L-3-hydroxytryptophan.
45326	protein-DNA covalent cross-linking via the 3'-end to peptidyl-tyrosine	P	The formation of a covalent cross-link between DNA and a peptidyl-tyrosine residue by the formation of O4'-(phospho-3'-DNA)-L-tyrosine.
45327	protein-DNA covalent cross-linking via peptidyl-tyrosine	P	The formation of a covalent cross-link between DNA and a peptidyl-tyrosine residue.
45328	cytochrome P450 4A1-heme linkage	P	The covalent linkage of heme to cytochrome P450 4A1 via hydroxyheme-L-glutamyl ester.
45329	carnitine biosynthetic process	P	The chemical reactions and pathways resulting in the formation of carnitine (hydroxy-trimethyl aminobutyric acid), a compound that participates in the transfer of acyl groups across the inner mitochondrial membrane.
45330	aspartyl esterase activity	F	Catalysis of the hydrolysis of an ester bond by a mechanism involving a catalytically active aspartic acid residue.
45332	phospholipid translocation	P	The movement of a phospholipid molecule from one leaflet of a membrane bilayer to the opposite leaflet.
45333	cellular respiration	P	The enzymatic release of energy from inorganic and organic compounds (especially carbohydrates and fats) which either requires oxygen (aerobic respiration) or does not (anaerobic respiration).
45334	clathrin-coated endocytic vesicle	C	A clathrin-coated, membrane-bounded intracellular vesicle formed by invagination of the plasma membrane around an extracellular substance.
45335	phagocytic vesicle	C	A membrane-bounded intracellular vesicle that arises from the ingestion of particulate material by phagocytosis.
45336	clathrin-coated phagocytic vesicle	C	A clathrin-coated, membrane-bounded intracellular vesicle that arises from the ingestion of particulate material by phagocytosis.
45337	farnesyl diphosphate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of farnesyl diphosphate.
45338	farnesyl diphosphate metabolic process	P	The chemical reactions and pathways involving farnesyl diphosphate, an intermediate in carotenoid, sesquiterpene, squalene and sterol biosynthesis, as well as a substrate in protein farnesylation.
45339	farnesyl diphosphate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of farnesyl diphosphate.
45340	mercury ion binding	F	Interacting selectively and non-covalently with mercury (Hg) ions.
45341	MHC class I biosynthetic process	P	The chemical reactions and pathways resulting in the formation of major histocompatibility protein class I.
45342	MHC class II biosynthetic process	P	The chemical reactions and pathways resulting in the formation of major histocompatibility protein class II.
45343	regulation of MHC class I biosynthetic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of MHC class I.
45344	negative regulation of MHC class I biosynthetic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of MHC class I.
45345	positive regulation of MHC class I biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of MHC class I.
45346	regulation of MHC class II biosynthetic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of MHC class II.
45347	negative regulation of MHC class II biosynthetic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of MHC class II.
45348	positive regulation of MHC class II biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of MHC class II.
45349	interferon-alpha biosynthetic process	P	The chemical reactions and pathways resulting in the formation of interferon-alpha.
45350	interferon-beta biosynthetic process	P	The chemical reactions and pathways resulting in the formation of interferon-beta.
45351	type I interferon biosynthetic process	P	The chemical reactions and pathways resulting in the formation of any type I interferon. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families.
45352	interleukin-1 Type I receptor antagonist activity	F	Blocks the binding of interleukin-1 to interleukin-1 Type I receptors.
45353	interleukin-1 Type II receptor antagonist activity	F	Blocks the binding of interleukin-1 to interleukin-1 Type II receptors.
45354	regulation of interferon-alpha biosynthetic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interferon-alpha.
45355	negative regulation of interferon-alpha biosynthetic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interferon-alpha.
45356	positive regulation of interferon-alpha biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interferon-alpha.
45357	regulation of interferon-beta biosynthetic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interferon-beta.
45358	negative regulation of interferon-beta biosynthetic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interferon-beta.
45359	positive regulation of interferon-beta biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interferon-beta.
45360	regulation of interleukin-1 biosynthetic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-1.
45361	negative regulation of interleukin-1 biosynthetic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-1.
45362	positive regulation of interleukin-1 biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-1.
45363	regulation of interleukin-11 biosynthetic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-11.
45364	negative regulation of interleukin-11 biosynthetic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-11.
45365	positive regulation of interleukin-11 biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-11.
45366	regulation of interleukin-13 biosynthetic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-13.
45367	negative regulation of interleukin-13 biosynthetic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-13.
45368	positive regulation of interleukin-13 biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-13.
45369	regulation of interleukin-14 biosynthetic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-14.
45370	negative regulation of interleukin-14 biosynthetic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-14.
45371	positive regulation of interleukin-14 biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-14.
45372	regulation of interleukin-15 biosynthetic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-15.
45373	negative regulation of interleukin-15 biosynthetic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-15.
45374	positive regulation of interleukin-15 biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-15.
45375	regulation of interleukin-16 biosynthetic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-16.
45376	negative regulation of interleukin-16 biosynthetic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-16.
45377	positive regulation of interleukin-16 biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-16.
45378	regulation of interleukin-17 biosynthetic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of any member of the interleukin-17 family of cytokines.
45379	negative regulation of interleukin-17 biosynthetic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of any member of the interleukin-17 family of cytokines.
45380	positive regulation of interleukin-17 biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of any member of the interleukin-17 family of cytokines.
45381	regulation of interleukin-18 biosynthetic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-18.
45382	negative regulation of interleukin-18 biosynthetic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-18.
45383	positive regulation of interleukin-18 biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-18.
45384	regulation of interleukin-19 biosynthetic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-19.
45385	negative regulation of interleukin-19 biosynthetic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-19.
45386	positive regulation of interleukin-19 biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-19.
45387	regulation of interleukin-20 biosynthetic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-20.
45388	negative regulation of interleukin-20 biosynthetic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-20.
45389	positive regulation of interleukin-20 biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-20.
45390	regulation of interleukin-21 biosynthetic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-21.
45391	negative regulation of interleukin-21 biosynthetic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-21.
45392	positive regulation of interleukin-21 biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-21.
45393	regulation of interleukin-22 biosynthetic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-22.
45394	negative regulation of interleukin-22 biosynthetic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-22.
45395	positive regulation of interleukin-22 biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-22.
45396	regulation of interleukin-23 biosynthetic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-23.
45397	negative regulation of interleukin-23 biosynthetic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-23.
45398	positive regulation of interleukin-23 biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-23.
45399	regulation of interleukin-3 biosynthetic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-3.
45400	negative regulation of interleukin-3 biosynthetic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-3.
45401	positive regulation of interleukin-3 biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-3.
45402	regulation of interleukin-4 biosynthetic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-4.
45403	negative regulation of interleukin-4 biosynthetic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-4.
45404	positive regulation of interleukin-4 biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-4.
45405	regulation of interleukin-5 biosynthetic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-5.
45406	negative regulation of interleukin-5 biosynthetic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-5.
45407	positive regulation of interleukin-5 biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-5.
45408	regulation of interleukin-6 biosynthetic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-6.
45409	negative regulation of interleukin-6 biosynthetic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-6.
45410	positive regulation of interleukin-6 biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-6.
45411	regulation of interleukin-7 biosynthetic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-7.
45412	negative regulation of interleukin-7 biosynthetic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-7.
45413	positive regulation of interleukin-7 biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-7.
45414	regulation of interleukin-8 biosynthetic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-8.
45415	negative regulation of interleukin-8 biosynthetic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-8.
45416	positive regulation of interleukin-8 biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-8.
45417	regulation of interleukin-9 biosynthetic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-9.
45418	negative regulation of interleukin-9 biosynthetic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-9.
45419	positive regulation of interleukin-9 biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-9.
45420	regulation of connective tissue growth factor biosynthetic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of connective tissue growth factor.
45421	negative regulation of connective tissue growth factor biosynthetic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of connective tissue growth factor.
45422	positive regulation of connective tissue growth factor biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of connective tissue growth factor.
45423	regulation of granulocyte macrophage colony-stimulating factor biosynthetic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of granulocyte macrophage colony-stimulating factor.
45424	negative regulation of granulocyte macrophage colony-stimulating factor biosynthetic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of granulocyte macrophage colony-stimulating factor.
45425	positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of granulocyte macrophage colony-stimulating factor.
45427	enzyme active site formation via (phospho-5'-guanosine)-L-histidine	P	The transient guanylylation of peptidyl-histidine to form (phospho-5'-guanosine)-L-histidine.
45428	regulation of nitric oxide biosynthetic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of nitric oxide.
45429	positive regulation of nitric oxide biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of nitric oxide.
45430	chalcone isomerase activity	F	Catalysis of the reaction: a chalcone = a flavanone.
45431	flavonol synthase activity	F	Catalysis of the reaction: a dihydroflavonol + 2-oxoglurate + O2 = a flavonol + succinate + CO2 + H2O.
45433	male courtship behavior, veined wing generated song production	P	The process during wing vibration where the male insect produces a species-specific acoustic signal called a love song.
45434	negative regulation of female receptivity, post-mating	P	Any process that stops, prevents or reduces the receptiveness of a female to male advances subsequent to mating.
45435	lycopene epsilon cyclase activity	F	Catalysis of the cyclization of an epsilon ring at one end of the lycopene molecule (psi, psi-carotene) to form delta-carotene (epsilon, psi-carotene).
45436	lycopene beta cyclase activity	F	Catalysis of the cyclization of beta rings at one or both ends of the lycopene molecule (psi, psi-carotene) to form gamma-carotene or the bicyclic beta-carotene (beta, beta-carotene), respectively.
45437	uridine nucleosidase activity	F	Catalysis of the reaction: H(2)O + uridine = ribofuranose + uracil.
45438	delta-(L-alpha-aminoadipyl)-L-cysteinyl-D-valine synthetase activity	F	Catalysis of the formation of delta-(L-alpha-aminoadipyl)-L-cysteinyl-D-valine from constituent amino acids and ATP in the presence of magnesium ions and dithioerythritol.
45439	isopenicillin-N epimerase activity	F	Catalysis of the reaction: isopenicillin N = penicillin N.
45442	deacetoxycephalosporin-C hydroxylase activity	F	Catalysis of the reaction: 2-oxoglutarate + deacetoxycephalosporin C + O(2) = CO(2) + deacetylcephalosporin C + succinate.
45443	juvenile hormone secretion	P	The regulated release of juvenile hormones, the three sesquiterpenoid derivatives that function to maintain the larval state of insects at molting and that may be required for other processes, e.g. oogenesis.
45444	fat cell differentiation	P	The process in which a relatively unspecialized cell acquires specialized features of an adipocyte, an animal connective tissue cell specialized for the synthesis and storage of fat.
45445	myoblast differentiation	P	The process in which a relatively unspecialized cell acquires specialized features of a myoblast. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into striated muscle fibers.
45446	endothelial cell differentiation	P	The process in which a mesodermal, bone marrow or neural crest cell acquires specialized features of an endothelial cell, a thin flattened cell. A layer of such cells lines the inside surfaces of body cavities, blood vessels, and lymph vessels, making up the endothelium.
45448	mitotic cell cycle, embryonic	P	The eukaryotic cell cycle in which a cell is duplicated without changing ploidy, occurring in the embryo.
45450	bicoid mRNA localization	P	Any process in which bicoid mRNA is transported to and maintained within the oocyte as part of the specification of the anterior/posterior axis.
45451	pole plasm oskar mRNA localization	P	Any process in which oskar mRNA is transported to, or maintained in, the oocyte pole plasm.
45453	bone resorption	P	The process in which specialized cells known as osteoclasts degrade the organic and inorganic portions of bone, and endocytose and transport the degradation products.
45454	cell redox homeostasis	P	Any process that maintains the redox environment of a cell or compartment within a cell.
45455	ecdysteroid metabolic process	P	The chemical reactions and pathways involving ecdysteroids, a group of polyhydroxylated ketosteroids ubiquitous in insects and other arthropods, in which they initiate post-embryonic development, including the metamorphosis of immature forms and the development of the reproductive system and the maturation of oocytes in adult females.
45456	ecdysteroid biosynthetic process	P	The chemical reactions and pathways resulting in the formation of ecdysteroids, a group of polyhydroxylated ketosteroids which initiate post-embryonic development.
45457	ecdysteroid secretion	P	The regulated release of ecdysteroids, a group of polyhydroxylated ketosteroids which initiate post-embryonic development.
45458	recombination within rDNA repeats	P	Genetic recombination within the DNA of the genes coding for ribosomal RNA.
45459	iron incorporation into iron-sulfur cluster via tetrakis-L-cysteinyl triiron tetrasulfide	P	The incorporation of iron into a 3Fe-4S iron-sulfur cluster via tetrakis-L-cysteinyl triiron tetrasulfide.
45460	sterigmatocystin metabolic process	P	The chemical reactions and pathways involving sterigmatocystin, a carcinogenic mycotoxin produced in high yields by strains of the common molds.
45461	sterigmatocystin biosynthetic process	P	The chemical reactions and pathways resulting in the formation of sterigmatocystin, a carcinogenic mycotoxin produced in high yields by strains of the common molds.
45462	trichothecene 3-O-acetyltransferase activity	F	Catalysis of the 3-O-acetylation of a trichothecene. Trichothecenes are sesquiterpene epoxide mycotoxins that act as potent inhibitors of eukaryotic protein synthesis.
45463	R8 cell development	P	The process whose specific outcome is the progression of the R8 photoreceptor over time, from its formation to the mature structure. The R8 photoreceptor is the founding receptor of each ommatidium.
45464	R8 cell fate specification	P	The process in which a cell becomes capable of differentiating autonomously into an R8 cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.
45465	R8 cell differentiation	P	The process in which a relatively unspecialized cell acquires the specialized features of the R8 photoreceptor.
45466	R7 cell differentiation	P	The process in which a relatively unspecialized cell acquires the specialized features of the R7 photoreceptor.
45467	R7 cell development	P	The process whose specific outcome is the progression of the R7 photoreceptor over time, from its formation to the mature structure. The R7 photoreceptor is the last photoreceptor to develop in the ommatidium.
45468	regulation of R8 cell spacing in compound eye	P	Any process that ensures that the R8 cells are selected in a precise progressive pattern so that they are evenly spaced throughout the eye disc.
45469	negative regulation of R8 cell spacing in compound eye	P	Any process that stops or prevents the correct R8 cell spacing pattern in a compound eye.
45470	R8 cell-mediated photoreceptor organization	P	The regionalization process that coordinates the recruitment and organization of other non-R8 photoreceptors by the R8 photoreceptor.
45471	response to ethanol	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ethanol stimulus.
45472	response to ether	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ether stimulus.
45475	locomotor rhythm	P	The rhythm of the locomotor activity of an organism during its 24 hour activity cycle.
45476	nurse cell apoptotic process	P	Any apoptotic process in a nurse cell. During late oogenesis, following the transfer of substances from the nurse cells to the oocyte, nurse cell remnants are cleared from the egg chamber by apoptotic process.
45477	regulation of nurse cell apoptotic process	P	Any process that modulates the frequency, rate or extent of nurse cell apoptotic process.
45478	fusome organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the fusome, a large intracellular spectrin-rich structure found in insect germline cells and mammalian hematopoietic cells.
45479	vesicle targeting to fusome	P	The recruitment of vesicles to the fusome. The vesicles become the fusome tubule network and are necessary for the assembly of the fusome.
45480	galactose oxidase activity	F	Catalysis of the reaction: D-galactose + O2 = D-galacto-hexodialdose + hydrogen peroxide.
45481	6-endo-hydroxycineole dehydrogenase activity	F	Catalysis of the reaction: 6-endo-hydroxycineole + NAD(+) = 6-oxocineole + H(+) + NADH.
45482	trichodiene synthase activity	F	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = diphosphate + trichodiene.
45483	aristolochene synthase activity	F	Catalysis of the reaction: trans,trans-farnesyl diphosphate = aristolochene + diphosphate.
45484	L-lysine 6-transaminase activity	F	Catalysis of the reaction: 2-oxoglutarate + L-lysine = L-glutamate + allysine.
45485	omega-6 fatty acid desaturase activity	F	Catalysis of the introduction of an omega-6 double bond into the fatty acid hydrocarbon chain.
45486	naringenin 3-dioxygenase activity	F	Catalysis of the reaction: naringenin + 2-oxoglutarate + O2 = dihydrokaempferol + succinate + CO2.
45487	gibberellin catabolic process	P	The chemical reactions and pathways resulting in the breakdown of gibberellin. Gibberellins are a class of highly modified terpenes that function as plant growth regulators.
45488	pectin metabolic process	P	The chemical reactions and pathways involving pectin, a group of galacturonic acid-containing, water-soluble colloidal carbohydrates of high molecular weight and of net negative charge.
45489	pectin biosynthetic process	P	The chemical reactions and pathways resulting in the formation of pectin, a polymer containing a backbone of alpha-1,4-linked D-galacturonic acid residues.
45490	pectin catabolic process	P	The chemical reactions and pathways resulting in the breakdown of pectin, a polymer containing a backbone of alpha-1,4-linked D-galacturonic acid residues.
45491	xylan metabolic process	P	The chemical reactions and pathways involving xylan, a polymer containing a beta-1,4-linked D-xylose backbone.
45492	xylan biosynthetic process	P	The chemical reactions and pathways resulting in the formation of xylan, a polymer containing a beta-1,4-linked D-xylose backbone.
45493	xylan catabolic process	P	The chemical reactions and pathways resulting in the breakdown of xylan, a polymer containing a beta-1,4-linked D-xylose backbone.
45494	photoreceptor cell maintenance	P	Any process preventing the degeneration of the photoreceptor, a specialized cell type that is sensitive to light.
45495	pole plasm	C	Differentiated cytoplasm associated with a pole (animal, vegetal, anterior, or posterior) of an oocyte, egg or early embryo.
45496	male analia development	P	The process whose specific outcome is the progression of the analia of the male over time, from formation to the mature structure. The analia is the posterior-most vertral appendage that develops from the genital disc. An example of this process is found in Drosophila melanogaster.
45497	female analia development	P	The process whose specific outcome is the progression of the analia of the female over time, from formation to the mature structure. The analia is the posterior-most vertral appendage that develops from the genital disc. An example of this process is found in Drosophila melanogaster.
45498	sex comb development	P	The process whose specific outcome is the progression of the sex comb over time, from its formation to the mature structure. The sex combs are the male specific chaetae located on the prothoracic tarsal segment of the prothoracic leg.
45499	chemorepellent activity	F	Providing the environmental signal that initiates the directed movement of a motile cell or organism towards a lower concentration of that signal.
45500	sevenless signaling pathway	P	A series of molecular signals initiated by the binding of an extracellular ligand to sevenless (sev; a receptor tyrosine kinase) on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.
45501	regulation of sevenless signaling pathway	P	Any process that modulates the frequency, rate or extent of the sevenless signaling pathway.
45502	dynein binding	F	Interacting selectively and non-covalently with dynein, the multisubunit protein complex that is associated with microtubules.
45503	dynein light chain binding	F	Interacting selectively and non-covalently with a light chain of the dynein complex.
45504	dynein heavy chain binding	F	Interacting selectively and non-covalently with a heavy chain of the dynein complex.
45505	dynein intermediate chain binding	F	Interacting selectively and non-covalently with an intermediate chain of the dynein complex.
45506	interleukin-24 receptor activity	F	Combining with interleukin-24 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
45507	interleukin-25 receptor activity	F	Combining with interleukin-25 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
45508	interleukin-26 receptor activity	F	Combining with interleukin-26 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
45509	interleukin-27 receptor activity	F	Combining with interleukin-27 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
45510	interleukin-24 binding	F	Interacting selectively and non-covalently with interleukin-24.
45511	interleukin-25 binding	F	Interacting selectively and non-covalently with interleukin-25.
45512	interleukin-26 binding	F	Interacting selectively and non-covalently with interleukin-26.
45513	interleukin-27 binding	F	Interacting selectively and non-covalently with interleukin-27.
45514	interleukin-16 receptor binding	F	Interacting selectively and non-covalently with the interleukin-16 receptor.
45515	interleukin-18 receptor binding	F	Interacting selectively and non-covalently with the interleukin-18 receptor.
45516	interleukin-19 receptor binding	F	Interacting selectively and non-covalently with the interleukin-19 receptor.
45517	interleukin-20 receptor binding	F	Interacting selectively and non-covalently with the interleukin-20 receptor.
45518	interleukin-22 receptor binding	F	Interacting selectively and non-covalently with the interleukin-22 receptor.
45519	interleukin-23 receptor binding	F	Interacting selectively and non-covalently with the interleukin-23 receptor.
45520	interleukin-24 receptor binding	F	Interacting selectively and non-covalently with the interleukin-24 receptor.
45521	interleukin-25 receptor binding	F	Interacting selectively and non-covalently with the interleukin-25 receptor.
45522	interleukin-26 receptor binding	F	Interacting selectively and non-covalently with the interleukin-26 receptor.
45523	interleukin-27 receptor binding	F	Interacting selectively and non-covalently with the interleukin-27 receptor.
45524	interleukin-24 biosynthetic process	P	The chemical reactions and pathways resulting in the formation of interleukin-24.
45525	interleukin-25 biosynthetic process	P	The chemical reactions and pathways resulting in the formation of interleukin-25.
45526	interleukin-26 biosynthetic process	P	The chemical reactions and pathways resulting in the formation of interleukin-26.
45527	interleukin-27 biosynthetic process	P	The chemical reactions and pathways resulting in the formation of interleukin-27.
45528	regulation of interleukin-24 biosynthetic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-24.
45529	regulation of interleukin-25 biosynthetic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-25.
45530	regulation of interleukin-26 biosynthetic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-26.
45531	regulation of interleukin-27 biosynthetic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-27.
45532	negative regulation of interleukin-24 biosynthetic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-24.
45533	negative regulation of interleukin-25 biosynthetic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-25.
45534	negative regulation of interleukin-26 biosynthetic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-26.
45535	negative regulation of interleukin-27 biosynthetic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-27.
45536	positive regulation of interleukin-24 biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-24.
45537	positive regulation of interleukin-25 biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-25.
45538	positive regulation of interleukin-26 biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-26.
45539	positive regulation of interleukin-27 biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-27.
45540	regulation of cholesterol biosynthetic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cholesterol.
45541	negative regulation of cholesterol biosynthetic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cholesterol.
45542	positive regulation of cholesterol biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cholesterol.
45543	gibberellin 2-beta-dioxygenase activity	F	Catalysis of the reaction: a gibberellin + 2-oxoglutarate + O2 = a 2-beta-hydroxygibberellin + succinate + CO2.
45544	gibberellin 20-oxidase activity	F	Catalysis of the oxidation of C-20 gibberellins to form the corresponding C-19 lactones.
45545	syndecan binding	F	Interacting selectively and non-covalently with syndecan, an integral membrane proteoglycan (250-300 kDa) associated largely with epithelial cells.
45547	dehydrodolichyl diphosphate synthase activity	F	Catalysis of the condensation of isopentenyl diphosphate and farnesyl diphosphate in the cis-configuration to form dehydrodolichyl diphosphate.
45548	phenylalanine ammonia-lyase activity	F	Catalysis of the reaction: L-phenylalanine = NH(4)(+) + trans-cinnamate.
45549	9-cis-epoxycarotenoid dioxygenase activity	F	Catalysis of the reactions: a 9-cis-epoxycarotenoid + O2 = 2-cis,4-trans-xanthoxin + a 12'-apo-carotenal; 9-cis-violaxanthin + O2 = 2-cis,4-trans-xanthoxin + (3S,5R,6S)-5,6-epoxy-3-hydroxy-5,6-dihydro-12'-apo-beta-caroten-12'-al; and 9'-cis-neoxanthin + O2 = 2-cis,4-trans-xanthoxin + (3S,5R,6R)-5,6-dihydroxy-6,7-didehydro-5,6-dihydro-12'-apo-beta-caroten-12'-al.
45550	geranylgeranyl reductase activity	F	Catalysis of the formation of phytyl group from the stepwise reduction of a geranylgeranyl group.
45551	cinnamyl-alcohol dehydrogenase activity	F	Catalysis of the reaction: cinnamyl alcohol + NADP+ = cinnamaldehyde + NADPH + H+.
45552	dihydrokaempferol 4-reductase activity	F	Catalysis of the reaction: cis-3,4-leucopelargonidin + NADP+ = (+)-dihydrokaempferol + NADPH + H+.
45553	TRAIL biosynthetic process	P	The chemical reactions and pathways resulting in the formation of TRAIL (TNF-related apoptosis inducing ligand). TRAIL induces apoptosis in a wide variety of cells and is a member of the tumor necrosis factor (TNF) family of cytokines.
45554	regulation of TRAIL biosynthetic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of TRAIL, TNF-related apoptosis inducing ligand.
45555	negative regulation of TRAIL biosynthetic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of TRAIL, TNF-related apoptosis inducing ligand.
45556	positive regulation of TRAIL biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of TRAIL, TNF-related apoptosis inducing ligand.
45557	TRAIL receptor biosynthetic process	P	The chemical reactions and pathways resulting in the formation of the TRAIL (TNF-related apoptosis inducing ligand) receptor.
45558	TRAIL receptor 1 biosynthetic process	P	The chemical reactions and pathways resulting in the formation of TRAIL-R1 (TNF-related apoptosis inducing ligand receptor 1), which engages a caspase-dependent apoptotic pathway.
45559	TRAIL receptor 2 biosynthetic process	P	The chemical reactions and pathways resulting in the formation of TRAIL-R2 (TNF-related apoptosis inducing ligand receptor 2), which engages a caspase-dependent apoptotic pathway and mediates apoptosis via the intracellular adaptor molecule FADD/MORT1.
45560	regulation of TRAIL receptor biosynthetic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of the TRAIL (TNF-related apoptosis inducing ligand) receptor.
45561	regulation of TRAIL receptor 1 biosynthetic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of TRAIL (TNF-related apoptosis inducing ligand) receptor 1.
45562	regulation of TRAIL receptor 2 biosynthetic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of TRAIL (TNF-related apoptosis inducing ligand) receptor 2.
45563	negative regulation of TRAIL receptor biosynthetic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of the TRAIL (TNF-related apoptosis inducing ligand) receptor.
45564	positive regulation of TRAIL receptor biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of the TRAIL (TNF-related apoptosis inducing ligand) receptor.
45565	negative regulation of TRAIL receptor 1 biosynthetic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of TRAIL (TNF-related apoptosis inducing ligand) receptor 1.
45566	positive regulation of TRAIL receptor 1 biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of TRAIL (TNF-related apoptosis inducing ligand) receptor 1.
45567	negative regulation of TRAIL receptor 2 biosynthetic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of TRAIL (TNF-related apoptosis inducing ligand) receptor 2.
45568	positive regulation of TRAIL receptor 2 biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of TRAIL (TNF-related apoptosis inducing ligand) receptor 2.
45569	TRAIL binding	F	Interacting selectively and non-covalently with TRAIL (TNF-related apoptosis inducing ligand), a member of the tumor necrosis factor ligand family that rapidly induces apoptosis in a variety of transformed cell lines.
45570	regulation of imaginal disc growth	P	Any process that modulates the frequency, rate or extent of the growth of the imaginal disc.
45571	negative regulation of imaginal disc growth	P	Any process that stops, prevents, or reduces the frequency, rate or extent of imaginal disc growth.
45572	positive regulation of imaginal disc growth	P	Any process that activates or increases the frequency, rate or extent of imaginal disc growth.
45574	sterigmatocystin catabolic process	P	The chemical reactions and pathways resulting in the breakdown of sterigmatocystin, a carcinogenic mycotoxin produced in high yields by strains of the common molds.
45575	basophil activation	P	The change in morphology and behavior of a basophil resulting from exposure to a cytokine, chemokine, soluble factor, or to (at least in mammals) an antigen which the basophil has specifically bound via IgE bound to Fc-epsilonRI receptors.
45576	mast cell activation	P	The change in morphology and behavior of a mast cell resulting from exposure to a cytokine, chemokine, soluble factor, or to (at least in mammals) an antigen which the mast cell has specifically bound via IgE bound to Fc-epsilonRI receptors.
45577	regulation of B cell differentiation	P	Any process that modulates the frequency, rate or extent of B cell differentiation.
45578	negative regulation of B cell differentiation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of B cell differentiation.
45579	positive regulation of B cell differentiation	P	Any process that activates or increases the frequency, rate or extent of B cell differentiation.
45580	regulation of T cell differentiation	P	Any process that modulates the frequency, rate or extent of T cell differentiation.
45581	negative regulation of T cell differentiation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of T cell differentiation.
45582	positive regulation of T cell differentiation	P	Any process that activates or increases the frequency, rate or extent of T cell differentiation.
45583	regulation of cytotoxic T cell differentiation	P	Any process that modulates the frequency, rate or extent of cytotoxic T cell differentiation.
45584	negative regulation of cytotoxic T cell differentiation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of cytotoxic T cell differentiation.
45585	positive regulation of cytotoxic T cell differentiation	P	Any process that activates or increases the frequency, rate or extent of cytotoxic T cell differentiation.
45586	regulation of gamma-delta T cell differentiation	P	Any process that modulates the frequency, rate or extent of gamma-delta T cell differentiation.
45587	negative regulation of gamma-delta T cell differentiation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of gamma-delta T cell differentiation.
45588	positive regulation of gamma-delta T cell differentiation	P	Any process that activates or increases the frequency, rate or extent of gamma-delta T cell differentiation.
45589	regulation of regulatory T cell differentiation	P	Any process that modulates the frequency, rate or extent of differentiation of regulatory T cells.
45590	negative regulation of regulatory T cell differentiation	P	Any process that stops, prevents, or reduces the rate of differentiation of regulatory T cells.
45591	positive regulation of regulatory T cell differentiation	P	Any process that activates or increases the frequency, rate or extent of differentiation of regulatory T cells.
45592	regulation of cumulus cell differentiation	P	Any process that modulates the frequency, rate or extent of ovarian cumulus cell differentiation.
45593	negative regulation of cumulus cell differentiation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of ovarian cumulus cell differentiation.
45594	positive regulation of cumulus cell differentiation	P	Any process that activates or increases the frequency, rate or extent of ovarian cumulus cell differentiation.
45595	regulation of cell differentiation	P	Any process that modulates the frequency, rate or extent of cell differentiation, the process in which relatively unspecialized cells acquire specialized structural and functional features.
45596	negative regulation of cell differentiation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of cell differentiation.
45597	positive regulation of cell differentiation	P	Any process that activates or increases the frequency, rate or extent of cell differentiation.
45598	regulation of fat cell differentiation	P	Any process that modulates the frequency, rate or extent of adipocyte differentiation.
45599	negative regulation of fat cell differentiation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of adipocyte differentiation.
45600	positive regulation of fat cell differentiation	P	Any process that activates or increases the frequency, rate or extent of adipocyte differentiation.
45601	regulation of endothelial cell differentiation	P	Any process that modulates the frequency, rate or extent of endothelial cell differentiation.
45602	negative regulation of endothelial cell differentiation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of endothelial cell differentiation.
45603	positive regulation of endothelial cell differentiation	P	Any process that activates or increases the frequency, rate or extent of endothelial cell differentiation.
45604	regulation of epidermal cell differentiation	P	Any process that modulates the frequency, rate or extent of epidermal cell differentiation.
45605	negative regulation of epidermal cell differentiation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of epidermal cell differentiation.
45606	positive regulation of epidermal cell differentiation	P	Any process that activates or increases the frequency, rate or extent of epidermal cell differentiation.
45607	regulation of auditory receptor cell differentiation	P	Any process that modulates the frequency, rate or extent of auditory hair cell differentiation.
45608	negative regulation of auditory receptor cell differentiation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of auditory hair cell differentiation.
45609	positive regulation of auditory receptor cell differentiation	P	Any process that activates or increases the frequency, rate or extent of auditory hair cell differentiation.
45610	regulation of hemocyte differentiation	P	Any process that modulates the frequency, rate or extent of hemocyte differentiation.
45611	negative regulation of hemocyte differentiation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of hemocyte differentiation.
45612	positive regulation of hemocyte differentiation	P	Any process that activates or increases the frequency, rate or extent of hemocyte differentiation.
45613	regulation of plasmatocyte differentiation	P	Any process that modulates the frequency, rate or extent of plasmatocyte differentiation.
45614	negative regulation of plasmatocyte differentiation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of plasmatocyte differentiation.
45615	positive regulation of plasmatocyte differentiation	P	Any process that activates or increases the frequency, rate or extent of plasmatocyte differentiation.
45616	regulation of keratinocyte differentiation	P	Any process that modulates the frequency, rate or extent of keratinocyte differentiation.
45617	negative regulation of keratinocyte differentiation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of keratinocyte differentiation.
45618	positive regulation of keratinocyte differentiation	P	Any process that activates or increases the frequency, rate or extent of keratinocyte differentiation.
45619	regulation of lymphocyte differentiation	P	Any process that modulates the frequency, rate or extent of lymphocyte differentiation.
45620	negative regulation of lymphocyte differentiation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of lymphocyte differentiation.
45621	positive regulation of lymphocyte differentiation	P	Any process that activates or increases the frequency, rate or extent of lymphocyte differentiation.
45622	regulation of T-helper cell differentiation	P	Any process that modulates the frequency, rate or extent of T-helper cell differentiation.
45623	negative regulation of T-helper cell differentiation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of T-helper cell differentiation.
45624	positive regulation of T-helper cell differentiation	P	Any process that activates or increases the frequency, rate or extent of T-helper cell differentiation.
45625	regulation of T-helper 1 cell differentiation	P	Any process that modulates the frequency, rate or extent of T-helper 1 cell differentiation.
45626	negative regulation of T-helper 1 cell differentiation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of T-helper 1 cell differentiation.
45627	positive regulation of T-helper 1 cell differentiation	P	Any process that activates or increases the frequency, rate or extent of T-helper 1 cell differentiation.
45628	regulation of T-helper 2 cell differentiation	P	Any process that modulates the frequency, rate or extent of T-helper 2 cell differentiation.
45629	negative regulation of T-helper 2 cell differentiation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of T-helper 2 cell differentiation.
45630	positive regulation of T-helper 2 cell differentiation	P	Any process that activates or increases the frequency, rate or extent of T-helper 2 cell differentiation.
45631	regulation of mechanoreceptor differentiation	P	Any process that modulates the frequency, rate or extent of mechanoreceptor differentiation.
45632	negative regulation of mechanoreceptor differentiation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of mechanoreceptor differentiation.
45633	positive regulation of mechanoreceptor differentiation	P	Any process that activates or increases the frequency, rate or extent of mechanoreceptor differentiation.
45634	regulation of melanocyte differentiation	P	Any process that modulates the frequency, rate or extent of melanocyte differentiation.
45635	negative regulation of melanocyte differentiation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of melanocyte differentiation.
45636	positive regulation of melanocyte differentiation	P	Any process that activates or increases the frequency, rate or extent of melanocyte differentiation.
45637	regulation of myeloid cell differentiation	P	Any process that modulates the frequency, rate or extent of myeloid cell differentiation.
45638	negative regulation of myeloid cell differentiation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of myeloid cell differentiation.
45639	positive regulation of myeloid cell differentiation	P	Any process that activates or increases the frequency, rate or extent of myeloid cell differentiation.
45640	regulation of basophil differentiation	P	Any process that modulates the frequency, rate or extent of basophil differentiation.
45641	negative regulation of basophil differentiation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of basophil differentiation.
45642	positive regulation of basophil differentiation	P	Any process that activates or increases the frequency, rate or extent of basophil differentiation.
45643	regulation of eosinophil differentiation	P	Any process that modulates the frequency, rate or extent of eosinophil differentiation.
45644	negative regulation of eosinophil differentiation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of eosinophil differentiation.
45645	positive regulation of eosinophil differentiation	P	Any process that activates or increases the frequency, rate or extent of eosinophil differentiation.
45646	regulation of erythrocyte differentiation	P	Any process that modulates the frequency, rate or extent of erythrocyte differentiation.
45647	negative regulation of erythrocyte differentiation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of erythrocyte differentiation.
45648	positive regulation of erythrocyte differentiation	P	Any process that activates or increases the frequency, rate or extent of erythrocyte differentiation.
45649	regulation of macrophage differentiation	P	Any process that modulates the frequency, rate or extent of macrophage differentiation.
45650	negative regulation of macrophage differentiation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of macrophage differentiation.
45651	positive regulation of macrophage differentiation	P	Any process that activates or increases the frequency, rate or extent of macrophage differentiation.
45652	regulation of megakaryocyte differentiation	P	Any process that modulates the frequency, rate or extent of megakaryocyte differentiation.
45653	negative regulation of megakaryocyte differentiation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of megakaryocyte differentiation.
45654	positive regulation of megakaryocyte differentiation	P	Any process that activates or increases the frequency, rate or extent of megakaryocyte differentiation.
45655	regulation of monocyte differentiation	P	Any process that modulates the frequency, rate or extent of monocyte differentiation.
45656	negative regulation of monocyte differentiation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of monocyte differentiation.
45657	positive regulation of monocyte differentiation	P	Any process that activates or increases the frequency, rate or extent of monocyte differentiation.
45658	regulation of neutrophil differentiation	P	Any process that modulates the frequency, rate or extent of neutrophil differentiation.
45659	negative regulation of neutrophil differentiation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of neutrophil differentiation.
45660	positive regulation of neutrophil differentiation	P	Any process that activates or increases the frequency, rate or extent of neutrophil differentiation.
45661	regulation of myoblast differentiation	P	Any process that modulates the frequency, rate or extent of myoblast differentiation. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.
45662	negative regulation of myoblast differentiation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of myoblast differentiation. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.
45663	positive regulation of myoblast differentiation	P	Any process that activates or increases the frequency, rate or extent of myoblast differentiation. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.
45664	regulation of neuron differentiation	P	Any process that modulates the frequency, rate or extent of neuron differentiation.
45665	negative regulation of neuron differentiation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of neuron differentiation.
45666	positive regulation of neuron differentiation	P	Any process that activates or increases the frequency, rate or extent of neuron differentiation.
45667	regulation of osteoblast differentiation	P	Any process that modulates the frequency, rate or extent of osteoblast differentiation.
45668	negative regulation of osteoblast differentiation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of osteoblast differentiation.
45669	positive regulation of osteoblast differentiation	P	Any process that activates or increases the frequency, rate or extent of osteoblast differentiation.
45670	regulation of osteoclast differentiation	P	Any process that modulates the frequency, rate or extent of osteoclast differentiation.
45671	negative regulation of osteoclast differentiation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of osteoclast differentiation.
45672	positive regulation of osteoclast differentiation	P	Any process that activates or increases the frequency, rate or extent of osteoclast differentiation.
45676	regulation of R7 cell differentiation	P	Any process that modulates the frequency, rate or extent of R7 differentiation.
45677	negative regulation of R7 cell differentiation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of R7cell differentiation.
45678	positive regulation of R7 cell differentiation	P	Any process that activates or increases the frequency, rate or extent of R7 cell differentiation.
45679	regulation of R8 cell differentiation	P	Any process that modulates the frequency, rate or extent of R8 differentiation.
45680	negative regulation of R8 cell differentiation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of R8 cell differentiation.
45681	positive regulation of R8 cell differentiation	P	Any process that activates or increases the frequency, rate or extent of R8 cell differentiation.
45682	regulation of epidermis development	P	Any process that modulates the frequency, rate or extent of epidermis development.
45683	negative regulation of epidermis development	P	Any process that stops, prevents, or reduces the frequency, rate or extent of epidermis development.
45684	positive regulation of epidermis development	P	Any process that activates or increases the frequency, rate or extent of epidermis development.
45685	regulation of glial cell differentiation	P	Any process that modulates the frequency, rate or extent of glia cell differentiation.
45686	negative regulation of glial cell differentiation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of glia cell differentiation.
45687	positive regulation of glial cell differentiation	P	Any process that activates or increases the frequency, rate or extent of glia cell differentiation.
45688	regulation of antipodal cell differentiation	P	Any process that modulates the frequency, rate or extent of antipodal cell differentiation.
45689	negative regulation of antipodal cell differentiation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of antipodal cell differentiation.
45690	positive regulation of antipodal cell differentiation	P	Any process that activates or increases the frequency, rate or extent of antipodal cell differentiation.
45691	regulation of embryo sac central cell differentiation	P	Any process that modulates the frequency, rate or extent of female gametophyte central cell differentiation.
45692	negative regulation of embryo sac central cell differentiation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of embryo sac central cell differentiation.
45693	positive regulation of embryo sac central cell differentiation	P	Any process that activates or increases the frequency, rate or extent of embryo sac central cell differentiation.
45694	regulation of embryo sac egg cell differentiation	P	Any process that modulates the frequency, rate or extent of embryo sac egg cell differentiation.
45695	negative regulation of embryo sac egg cell differentiation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of embryo sac egg cell differentiation.
45696	positive regulation of embryo sac egg cell differentiation	P	Any process that activates or increases the frequency, rate or extent of embryo sac egg cell differentiation.
45697	regulation of synergid differentiation	P	Any process that modulates the frequency, rate or extent of synergid cell differentiation.
45698	negative regulation of synergid differentiation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of synergid cell differentiation.
45699	positive regulation of synergid differentiation	P	Any process that activates or increases the frequency, rate or extent of synergid cell differentiation.
45700	regulation of spermatid nuclear differentiation	P	Any process that modulates the frequency, rate or extent of spermatid nuclear differentiation.
45701	negative regulation of spermatid nuclear differentiation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of spermatid nuclear differentiation.
45702	positive regulation of spermatid nuclear differentiation	P	Any process that activates or increases the frequency, rate or extent of spermatid nuclear differentiation.
45703	ketoreductase activity	F	Catalysis of the reduction of a ketone group to form the corresponding alcohol.
45704	regulation of salivary gland boundary specification	P	Any process that modulates the frequency, rate or extent of salivary gland determination.
45705	negative regulation of salivary gland boundary specification	P	Any process that stops, prevents, or reduces the frequency, rate or extent of salivary gland determination.
45706	positive regulation of salivary gland boundary specification	P	Any process that activates or increases the frequency, rate or extent of salivary gland determination.
45707	regulation of adult salivary gland boundary specification	P	Any process that modulates the frequency, rate or extent of salivary gland determination in an adult organism.
45708	regulation of larval salivary gland boundary specification	P	Any process that modulates the frequency, rate or extent of salivary gland determination in a larval organism.
45709	negative regulation of adult salivary gland boundary specification	P	Any process that stops, prevents, or reduces the frequency, rate or extent of salivary gland determination in an adult organism.
45710	negative regulation of larval salivary gland boundary specification	P	Any process that stops, prevents, or reduces the frequency, rate or extent of salivary gland determination in a larval organism.
45711	positive regulation of adult salivary gland boundary specification	P	Any process that activates or increases the frequency, rate or extent of salivary gland determination in an adult organism.
45712	positive regulation of larval salivary gland boundary specification	P	Any process that activates or increases the frequency, rate or extent of salivary gland determination in a larval organism.
45713	low-density lipoprotein particle receptor biosynthetic process	P	The chemical reactions and pathways resulting in the formation of low-density lipoprotein receptors, cell surface proteins that mediate the endocytosis of low-density lipoprotein particles by cells.
45714	regulation of low-density lipoprotein particle receptor biosynthetic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of low-density lipoprotein particle receptors.
45715	negative regulation of low-density lipoprotein particle receptor biosynthetic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of low-density lipoprotein particle receptors.
45716	positive regulation of low-density lipoprotein particle receptor biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of low-density lipoprotein receptors.
45717	negative regulation of fatty acid biosynthetic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of fatty acids.
45719	negative regulation of glycogen biosynthetic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glycogen.
45720	negative regulation of integrin biosynthetic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of integrins.
45721	negative regulation of gluconeogenesis	P	Any process that stops, prevents, or reduces the frequency, rate or extent of gluconeogenesis.
45722	positive regulation of gluconeogenesis	P	Any process that activates or increases the frequency, rate or extent of gluconeogenesis.
45723	positive regulation of fatty acid biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of fatty acids.
45724	positive regulation of cilium assembly	P	Any process that activates or increases the frequency, rate or extent of the formation of a cilium.
45725	positive regulation of glycogen biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glycogen.
45726	positive regulation of integrin biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of integrins.
45727	positive regulation of translation	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA.
45728	respiratory burst after phagocytosis	P	A phase of elevated metabolic activity, during which oxygen consumption increases, that occurs in neutrophils, monocytes, and macrophages shortly after phagocytosing material. An enhanced uptake of oxygen leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals, which play a part in microbiocidal activity.
45729	respiratory burst at fertilization	P	The phase of elevated metabolic activity, during which oxygen consumption increases, that occurs at fertilization. An enhanced uptake of oxygen leads to the production of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals. Capacitation, a necessary prerequisite event to successful fertilization, can be induced by reactive oxygen species in vitro; hydrogen peroxide is used as an extracellular oxidant to cross-link the protective surface envelopes.
45730	respiratory burst	P	A phase of elevated metabolic activity, during which oxygen consumption increases; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals.
45732	positive regulation of protein catabolic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds.
45733	acetate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of acetate, the anion of acetic acid.
45734	regulation of acetate catabolic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of acetate, the anion of acetic acid.
45735	nutrient reservoir activity	F	Functions in the storage of nutritious substrates.
45736	negative regulation of cyclin-dependent protein serine/threonine kinase activity	P	Any process that stops, prevents, or reduces the frequency, rate or extent of cyclin-dependent protein serine/threonine kinase activity.
45737	positive regulation of cyclin-dependent protein serine/threonine kinase activity	P	Any process that activates or increases the frequency, rate or extent of CDK activity.
45738	negative regulation of DNA repair	P	Any process that stops, prevents, or reduces the frequency, rate or extent of DNA repair.
45739	positive regulation of DNA repair	P	Any process that activates or increases the frequency, rate or extent of DNA repair.
45740	positive regulation of DNA replication	P	Any process that activates or increases the frequency, rate or extent of DNA replication.
45741	positive regulation of epidermal growth factor-activated receptor activity	P	Any process that activates or increases the frequency, rate or extent of EGF-activated receptor activity.
45742	positive regulation of epidermal growth factor receptor signaling pathway	P	Any process that activates or increases the frequency, rate or extent of epidermal growth factor receptor signaling pathway activity.
45743	positive regulation of fibroblast growth factor receptor signaling pathway	P	Any process that activates or increases the frequency, rate or extent of fibroblast growth factor receptor signaling pathway activity.
45744	negative regulation of G-protein coupled receptor protein signaling pathway	P	Any process that stops, prevents, or reduces the frequency, rate or extent of G-protein coupled receptor protein signaling pathway activity.
45745	positive regulation of G-protein coupled receptor protein signaling pathway	P	Any process that activates or increases the frequency, rate or extent of G-protein coupled receptor protein signaling pathway activity.
45746	negative regulation of Notch signaling pathway	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the Notch signaling pathway.
45747	positive regulation of Notch signaling pathway	P	Any process that activates or increases the frequency, rate or extent of the Notch signaling pathway.
45748	positive regulation of R8 cell spacing in compound eye	P	Any process that activates or enforces the correct R8 cell spacing in a compound eye.
45751	negative regulation of Toll signaling pathway	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the Tl signaling pathway.
45752	positive regulation of Toll signaling pathway	P	Any process that activates or increases the frequency, rate or extent of the Tl signaling pathway.
45753	negative regulation of acetate catabolic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of acetate.
45754	positive regulation of acetate catabolic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of acetate.
45755	negative regulation of initiation of acetate catabolic process by acetate	P	Any process that stops or prevents the activation, by acetate, of the chemical reactions and pathways resulting in the breakdown of acetate.
45756	positive regulation of initiation of acetate catabolic process by acetate	P	Any process that activates or increases the frequency, rate or extent of the activation, by acetate, of the chemical reactions and pathways resulting in the breakdown of acetate.
45759	negative regulation of action potential	P	Any process that stops, prevents, or reduces the frequency, rate or extent of action potential creation, propagation or termination. This typically occurs via modulation of the activity or expression of voltage-gated ion channels.
45760	positive regulation of action potential	P	Any process that activates or increases the frequency, rate or extent of action potential creation, propagation or termination. This typically occurs via modulation of the activity or expression of voltage-gated ion channels.
45761	regulation of adenylate cyclase activity	P	Any process that modulates the frequency, rate or extent of adenylate cyclase activity.
45762	positive regulation of adenylate cyclase activity	P	Any process that activates or increases the frequency, rate or extent of adenylate cyclase activity.
45763	negative regulation of cellular amino acid metabolic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving amino acid.
45764	positive regulation of cellular amino acid metabolic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving amino acid.
45765	regulation of angiogenesis	P	Any process that modulates the frequency, rate or extent of angiogenesis.
45766	positive regulation of angiogenesis	P	Any process that activates or increases angiogenesis.
45769	negative regulation of asymmetric cell division	P	Any process that stops, prevents, or reduces the frequency, rate or extent of asymmetric cell division.
45770	positive regulation of asymmetric cell division	P	Any process that activates or increases the frequency, rate or extent of asymmetric cell division.
45771	negative regulation of autophagosome size	P	Any process that reduces autophagosome size.
45772	positive regulation of autophagosome size	P	Any process that increases autophagosome size.
45773	positive regulation of axon extension	P	Any process that activates or increases the frequency, rate or extent of axon extension.
45774	negative regulation of beta 2 integrin biosynthetic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of beta 2 integrins.
45775	positive regulation of beta 2 integrin biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of beta 2 integrins.
45776	negative regulation of blood pressure	P	Any process in which the force of blood traveling through the circulatory system is decreased.
45777	positive regulation of blood pressure	P	Any process in which the force of blood traveling through the circulatory system is increased.
45778	positive regulation of ossification	P	Any process that activates or increases the frequency, rate or extent of bone formation.
45779	negative regulation of bone resorption	P	Any process that stops, prevents, or reduces the frequency, rate or extent of bone resorption.
45780	positive regulation of bone resorption	P	Any process that activates or increases the frequency, rate or extent of bone resorption.
45781	negative regulation of cell budding	P	Any process that stops, prevents, or reduces the frequency, rate or extent of cell budding.
45782	positive regulation of cell budding	P	Any process that activates or increases the frequency, rate or extent of cell budding.
45785	positive regulation of cell adhesion	P	Any process that activates or increases the frequency, rate or extent of cell adhesion.
45786	negative regulation of cell cycle	P	Any process that stops, prevents or reduces the rate or extent of progression through the cell cycle.
45787	positive regulation of cell cycle	P	Any process that activates or increases the rate or extent of progression through the cell cycle.
45792	negative regulation of cell size	P	Any process that reduces cell size.
45793	positive regulation of cell size	P	Any process that increases cell size.
45794	negative regulation of cell volume	P	Any process that decreases cell volume.
45795	positive regulation of cell volume	P	Any process that increases cell volume.
45796	negative regulation of intestinal cholesterol absorption	P	Any process that stops, prevents, or reduces the frequency, rate or extent of uptake of cholesterol into the blood by absorption from the intestine.
45797	positive regulation of intestinal cholesterol absorption	P	Any process that activates or increases the frequency, rate or extent of uptake of cholesterol into the blood by absorption from the intestine.
45798	negative regulation of chromatin assembly or disassembly	P	Any process that stops, prevents, or reduces the frequency, rate or extent of chromatin assembly or disassembly.
45799	positive regulation of chromatin assembly or disassembly	P	Any process that activates or increases the frequency, rate or extent of chromatin assembly or disassembly.
45800	negative regulation of chitin-based cuticle tanning	P	Any process that stops, prevents, or reduces the frequency, rate or extent of chitin-based cuticular tanning.
45801	positive regulation of chitin-based cuticle tanning	P	Any process that activates or increases the frequency, rate or extent of chitin-based cuticular tanning.
45804	negative regulation of eclosion	P	Any process that stops, prevents, or reduces the frequency, rate or extent of eclosion.
45805	positive regulation of eclosion	P	Any process that activates or increases the frequency, rate or extent of eclosion.
45806	negative regulation of endocytosis	P	Any process that stops, prevents, or reduces the frequency, rate or extent of endocytosis.
45807	positive regulation of endocytosis	P	Any process that activates or increases the frequency, rate or extent of endocytosis.
45808	negative regulation of establishment of competence for transformation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of establishment of competence for transformation.
45809	positive regulation of establishment of competence for transformation	P	Any process that activates or increases the frequency, rate or extent of establishment of competence for transformation.
45812	negative regulation of Wnt signaling pathway, calcium modulating pathway	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors leads to an increase in intracellular calcium and activation of protein kinase C (PKC).
45813	positive regulation of Wnt signaling pathway, calcium modulating pathway	P	Any process that activates or increases the frequency, rate or extent of the series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors leads to an increase in intracellular calcium and activation of protein kinase C (PKC).
45814	negative regulation of gene expression, epigenetic	P	Any epigenetic process that stops, prevents or reduces the rate of gene expression.
45815	positive regulation of gene expression, epigenetic	P	Any epigenetic process that activates or increases the rate of gene expression.
45818	negative regulation of glycogen catabolic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glycogen.
45819	positive regulation of glycogen catabolic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of glycogen.
45820	negative regulation of glycolytic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of glycolysis.
45821	positive regulation of glycolytic process	P	Any process that activates or increases the frequency, rate or extent of glycolysis.
45822	negative regulation of heart contraction	P	Any process that stops, prevents, or reduces the frequency, rate or extent of heart contraction.
45823	positive regulation of heart contraction	P	Any process that activates or increases the frequency, rate or extent of heart contraction.
45824	negative regulation of innate immune response	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the innate immune response.
45827	negative regulation of isoprenoid metabolic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving isoprenoid.
45828	positive regulation of isoprenoid metabolic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving isoprenoid.
45829	negative regulation of isotype switching	P	Any process that stops, prevents, or reduces the frequency, rate or extent of isotype switching.
45830	positive regulation of isotype switching	P	Any process that activates or increases the frequency, rate or extent of isotype switching.
45831	negative regulation of light-activated channel activity	P	Any process that stops, prevents, or reduces the frequency, rate or extent of light-activated channel activity.
45832	positive regulation of light-activated channel activity	P	Any process that activates or increases the frequency, rate or extent of light-activated channel activity.
45833	negative regulation of lipid metabolic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving lipids.
45834	positive regulation of lipid metabolic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving lipids.
45835	negative regulation of meiotic nuclear division	P	Any process that stops, prevents, or reduces the frequency, rate or extent of meiosis.
45836	positive regulation of meiotic nuclear division	P	Any process that activates or increases the frequency, rate or extent of meiosis.
45837	negative regulation of membrane potential	P	Any process that stops, prevents, or reduces the frequency, rate or extent of establishment or extent of a membrane potential, the electric potential existing across any membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane.
45838	positive regulation of membrane potential	P	Any process that activates or increases the frequency, rate or extent of establishment or extent of a membrane potential, the electric potential existing across any membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane.
45839	negative regulation of mitotic nuclear division	P	Any process that stops, prevents or reduces the rate or extent of mitosis. Mitosis is the division of the eukaryotic cell nucleus to produce two daughter nuclei that, usually, contain the identical chromosome complement to their mother.
45840	positive regulation of mitotic nuclear division	P	Any process that activates or increases the frequency, rate or extent of mitosis.
45841	negative regulation of mitotic metaphase/anaphase transition	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the cell cycle process in which a cell progresses from metaphase to anaphase during mitosis, triggered by the activation of the anaphase promoting complex by Cdc20/Sleepy homolog which results in the degradation of Securin.
45842	positive regulation of mitotic metaphase/anaphase transition	P	Any process that activates or increases the frequency, rate or extent of the cell cycle process in which a cell progresses from metaphase to anaphase during mitosis, triggered by the activation of the anaphase promoting complex by Cdc20/Sleepy homolog which results in the degradation of Securin.
45843	negative regulation of striated muscle tissue development	P	Any process that stops, prevents, or reduces the frequency, rate or extent of striated muscle development.
45844	positive regulation of striated muscle tissue development	P	Any process that activates or increases the frequency, rate or extent of striated muscle development.
45847	negative regulation of nitrogen utilization	P	Any process that stops, prevents, or reduces the frequency, rate or extent of nitrogen utilization.
45848	positive regulation of nitrogen utilization	P	Any process that activates or increases the frequency, rate or extent of nitrogen utilization.
45849	negative regulation of nurse cell apoptotic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of nurse cell apoptotic process.
45850	positive regulation of nurse cell apoptotic process	P	Any process that activates or increases the frequency, rate or extent of nurse cell apoptotic process.
45851	pH reduction	P	Any process that reduces the internal pH of an organism, part of an organism or a cell, measured by the concentration of the hydrogen ion.
45852	pH elevation	P	Any process that increases the internal pH of an organism, part of an organism or a cell, measured by the concentration of the hydrogen ion.
45853	negative regulation of bicoid mRNA localization	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the process in which bicoid mRNA is transported to, or maintained in, a specific location.
45854	positive regulation of bicoid mRNA localization	P	Any process that activates or increases the frequency, rate or extent of the process in which bicoid mRNA is transported to, or maintained in, a specific location.
45855	negative regulation of pole plasm oskar mRNA localization	P	Any process that stops, prevents, or reduces the frequency, rate or extent of a process in which oskar mRNA is transported to, or maintained in, the oocyte pole plasm.
45856	positive regulation of pole plasm oskar mRNA localization	P	Any process that activates or increases the frequency, rate or extent of the process in which oskar mRNA is transported to, or maintained in, the oocyte pole plasm.
45857	negative regulation of molecular function, epigenetic	P	Any heritable epigenetic process that stops, prevents, or reduces the frequency, rate or extent of protein function by self-perpetuating conformational conversions of normal proteins in healthy cells. This is distinct from, though mechanistically analogous to, disease states associated with prion propagation and amyloidogenesis. A single protein, if it carries a glutamine/asparagine-rich ('prion') domain, can sometimes stably exist in at least two distinct physical states, each associated with a different phenotype; propagation of one of these traits is achieved by a self-perpetuating change in the protein from one form to the other, mediated by conformational changes in the glutamine/asparagine-rich domain. Prion domains are both modular and transferable to other proteins, on which they can confer a heritable epigenetic alteration of function; existing bioinformatics data indicate that they are rare in non-eukarya, but common in eukarya.
45858	positive regulation of molecular function, epigenetic	P	Any heritable epigenetic process that increases the frequency, rate or extent of protein function by self-perpetuating conformational conversions of normal proteins in healthy cells. This is distinct from, though mechanistically analogous to, disease states associated with prion propagation and amyloidogenesis. A single protein, if it carries a glutamine/asparagine-rich ('prion') domain, can sometimes stably exist in at least two distinct physical states, each associated with a different phenotype; propagation of one of these traits is achieved by a self-perpetuating change in the protein from one form to the other, mediated by conformational changes in the glutamine/asparagine-rich domain. Prion domains are both modular and transferable to other proteins, on which they can confer a heritable epigenetic alteration of function; existing bioinformatics data indicate that they are rare in non-eukarya, but common in eukarya.
45859	regulation of protein kinase activity	P	Any process that modulates the frequency, rate or extent of protein kinase activity.
45860	positive regulation of protein kinase activity	P	Any process that activates or increases the frequency, rate or extent of protein kinase activity.
45861	negative regulation of proteolysis	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the hydrolysis of a peptide bond or bonds within a protein.
45862	positive regulation of proteolysis	P	Any process that activates or increases the frequency, rate or extent of the hydrolysis of a peptide bond or bonds within a protein.
45863	negative regulation of pteridine metabolic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving pteridine.
45864	positive regulation of pteridine metabolic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving pteridine.
45869	negative regulation of single stranded viral RNA replication via double stranded DNA intermediate	P	Any process that stops, prevents, or reduces the frequency, rate or extent of single stranded viral RNA replication via double stranded DNA intermediate.
45870	positive regulation of single stranded viral RNA replication via double stranded DNA intermediate	P	Any process that activates or increases the frequency, rate or extent of retroviral genome replication.
45871	negative regulation of rhodopsin gene expression	P	Any process that stops, prevents, or reduces the frequency, rate or extent of rhodopsin gene expression.
45872	positive regulation of rhodopsin gene expression	P	Any process that activates or increases the frequency, rate or extent of rhodopsin gene expression.
45873	negative regulation of sevenless signaling pathway	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the sevenless signaling pathway.
45874	positive regulation of sevenless signaling pathway	P	Any process that activates or increases the frequency, rate or extent of the sevenless signaling pathway.
45875	negative regulation of sister chromatid cohesion	P	Any process that stops, prevents, or reduces the frequency, rate or extent of sister chromatid cohesion.
45876	positive regulation of sister chromatid cohesion	P	Any process that activates or increases the frequency, rate or extent of sister chromatid cohesion.
45879	negative regulation of smoothened signaling pathway	P	Any process that stops, prevents, or reduces the frequency, rate or extent of smoothened signaling.
45880	positive regulation of smoothened signaling pathway	P	Any process that activates or increases the frequency, rate or extent of smoothened signaling.
45881	positive regulation of sporulation resulting in formation of a cellular spore	P	Any process that activates or increases the frequency, rate or extent of sporulation.
45882	negative regulation of sulfur utilization	P	Any process that stops, prevents, or reduces the frequency, rate or extent of sulfur utilization.
45883	positive regulation of sulfur utilization	P	Any process that activates or increases the frequency, rate or extent of sulfur utilization.
45886	negative regulation of synaptic growth at neuromuscular junction	P	Any process that stops, prevents, or reduces the frequency, rate or extent of synaptic growth at neuromuscular junction.
45887	positive regulation of synaptic growth at neuromuscular junction	P	Any process that activates or increases the frequency, rate or extent of synaptic growth at neuromuscular junction.
45892	negative regulation of transcription, DNA-templated	P	Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
45893	positive regulation of transcription, DNA-templated	P	Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
45894	negative regulation of mating-type specific transcription, DNA-templated	P	Any mating-type specific process that stops, prevents or reduces the rate of cellular DNA-templated transcription.
45895	positive regulation of mating-type specific transcription, DNA-templated	P	Any mating-type specific process that activates or increases the rate of cellular DNA-templated transcription.
45896	regulation of transcription during mitotic cell cycle	P	A cell cycle process that modulates the frequency, rate or extent of transcription that occurs during the mitotic cell cycle.
45897	positive regulation of transcription during mitotic cell cycle	P	Any process that activates or increases the frequency, rate or extent of transcription that occurs during the mitotic cell cycle.
45898	regulation of RNA polymerase II transcriptional preinitiation complex assembly	P	Any process that modulates the frequency, rate or extent of RNA polymerase II transcriptional preinitiation complex assembly.
45899	positive regulation of RNA polymerase II transcriptional preinitiation complex assembly	P	Any process that activates or increases the frequency, rate or extent of RNA polymerase II transcriptional preinitiation complex assembly.
45900	negative regulation of translational elongation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of translational elongation.
45901	positive regulation of translational elongation	P	Any process that activates or increases the frequency, rate or extent of translational elongation.
45902	negative regulation of translational fidelity	P	Any process that decreases the ability of the translational apparatus to interpret the genetic code.
45903	positive regulation of translational fidelity	P	Any process that increases the ability of the translational apparatus to interpret the genetic code.
45904	negative regulation of translational termination	P	Any process that stops, prevents, or reduces the frequency, rate or extent of translational termination.
45905	positive regulation of translational termination	P	Any process that activates or increases the frequency, rate or extent of translational termination.
45906	negative regulation of vasoconstriction	P	Any process that stops, prevents, or reduces the frequency, rate or extent of vasoconstriction.
45907	positive regulation of vasoconstriction	P	Any process that activates or increases the frequency, rate or extent of vasoconstriction.
45908	negative regulation of vasodilation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of vasodilation.
45909	positive regulation of vasodilation	P	Any process that activates or increases the frequency, rate or extent of vasodilation.
45910	negative regulation of DNA recombination	P	Any process that stops, prevents, or reduces the frequency, rate or extent of DNA recombination.
45911	positive regulation of DNA recombination	P	Any process that activates or increases the frequency, rate or extent of DNA recombination.
45912	negative regulation of carbohydrate metabolic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving carbohydrate.
45913	positive regulation of carbohydrate metabolic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving carbohydrate.
45914	negative regulation of catecholamine metabolic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving catecholamine.
45915	positive regulation of catecholamine metabolic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving catecholamine.
45916	negative regulation of complement activation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of complement activation.
45917	positive regulation of complement activation	P	Any process that activates or increases the frequency, rate or extent of complement activation.
45918	negative regulation of cytolysis	P	Any process that stops, prevents, or reduces the frequency, rate or extent of cytolysis.
45919	positive regulation of cytolysis	P	Any process that activates or increases the frequency, rate or extent of cytolysis.
45920	negative regulation of exocytosis	P	Any process that stops, prevents, or reduces the frequency, rate or extent of exocytosis.
45921	positive regulation of exocytosis	P	Any process that activates or increases the frequency, rate or extent of exocytosis.
45922	negative regulation of fatty acid metabolic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving fatty acids.
45923	positive regulation of fatty acid metabolic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving fatty acids.
45924	regulation of female receptivity	P	Any process that modulates the frequency, rate or extent of the willingness or readiness of a female to receive male advances.
45925	positive regulation of female receptivity	P	Any process that activates or increases the receptiveness of a female to male advances.
45926	negative regulation of growth	P	Any process that stops, prevents or reduces the rate or extent of growth, the increase in size or mass of all or part of an organism.
45927	positive regulation of growth	P	Any process that activates or increases the rate or extent of growth, the increase in size or mass of all or part of an organism.
45928	negative regulation of juvenile hormone metabolic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving juvenile hormone.
45929	positive regulation of juvenile hormone metabolic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving juvenile hormone.
45930	negative regulation of mitotic cell cycle	P	Any process that stops, prevents or reduces the rate or extent of progression through the mitotic cell cycle.
45931	positive regulation of mitotic cell cycle	P	Any process that activates or increases the rate or extent of progression through the mitotic cell cycle.
45932	negative regulation of muscle contraction	P	Any process that stops, prevents, or reduces the frequency, rate or extent of muscle contraction.
45933	positive regulation of muscle contraction	P	Any process that activates or increases the frequency, rate or extent of muscle contraction.
45934	negative regulation of nucleobase-containing compound metabolic process	P	Any cellular process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids.
45935	positive regulation of nucleobase-containing compound metabolic process	P	Any cellular process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving nucleobases, nucleosides, nucleotides and nucleic acids.
45936	negative regulation of phosphate metabolic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving phosphates.
45937	positive regulation of phosphate metabolic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving phosphates.
45938	positive regulation of circadian sleep/wake cycle, sleep	P	Any process that activates or increases the duration or quality of sleep, a readily reversible state of reduced awareness and metabolic activity that occurs periodically in many animals.
45939	negative regulation of steroid metabolic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving steroids.
45940	positive regulation of steroid metabolic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving steroids.
45942	negative regulation of phosphorus utilization	P	Any process that stops, prevents, or reduces the frequency, rate or extent of phosphorus utilization.
45943	positive regulation of transcription from RNA polymerase I promoter	P	Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase I promoter.
45944	positive regulation of transcription from RNA polymerase II promoter	P	Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
45945	positive regulation of transcription from RNA polymerase III promoter	P	Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase III promoter.
45947	negative regulation of translational initiation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of translational initiation.
45948	positive regulation of translational initiation	P	Any process that activates or increases the frequency, rate or extent of translational initiation.
45949	positive regulation of phosphorus utilization	P	Any process that activates or increases the frequency, rate or extent of phosphorus utilization.
45950	negative regulation of mitotic recombination	P	Any process that inhibits or decreases the rate of DNA recombination during mitosis.
45951	positive regulation of mitotic recombination	P	Any process that activates or increases the frequency, rate or extent of DNA recombination during mitosis.
45952	regulation of juvenile hormone catabolic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of juvenile hormone.
45953	negative regulation of natural killer cell mediated cytotoxicity	P	Any process that stops, prevents, or reduces the rate of natural killer mediated cytotoxicity.
45954	positive regulation of natural killer cell mediated cytotoxicity	P	Any process that activates or increases the frequency, rate or extent of natural killer cell mediated cytotoxicity.
45955	negative regulation of calcium ion-dependent exocytosis	P	Any process that stops, prevents, or reduces the frequency, rate or extent of calcium ion-dependent exocytosis.
45956	positive regulation of calcium ion-dependent exocytosis	P	Any process that activates or increases the frequency, rate or extent of calcium ion-dependent exocytosis.
45957	negative regulation of complement activation, alternative pathway	P	Any process that stops, prevents, or reduces the frequency, rate or extent of complement activation by the alternative pathway.
45958	positive regulation of complement activation, alternative pathway	P	Any process that activates or increases the frequency, rate or extent of complement activation by the alternative pathway.
45959	negative regulation of complement activation, classical pathway	P	Any process that stops, prevents, or reduces the frequency, rate or extent of complement activation by the classical pathway.
45960	positive regulation of complement activation, classical pathway	P	Any process that activates or increases the frequency, rate or extent of complement activation by the classical pathway.
45961	negative regulation of development, heterochronic	P	Any process that modulates the consistent predetermined time point at which an integrated living unit or organism progresses from an initial condition to a later condition and decreases the rate at which this time point is reached.
45962	positive regulation of development, heterochronic	P	Any process that modulates the consistent predetermined time point at which an integrated living unit or organism progresses from an initial condition to a later condition and increases the rate at which this time point is reached.
45963	negative regulation of dopamine metabolic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving dopamine.
45964	positive regulation of dopamine metabolic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving dopamine.
45965	negative regulation of ecdysteroid metabolic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving ecdysteroids.
45966	positive regulation of ecdysteroid metabolic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving ecdysteroids.
45967	negative regulation of growth rate	P	Any process that reduces the rate of growth of all or part of an organism.
45968	negative regulation of juvenile hormone biosynthetic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of juvenile hormone.
45969	positive regulation of juvenile hormone biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of juvenile hormone.
45970	negative regulation of juvenile hormone catabolic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of juvenile hormone.
45971	positive regulation of juvenile hormone catabolic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of juvenile hormone.
45972	negative regulation of juvenile hormone secretion	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of juvenile hormone.
45973	positive regulation of juvenile hormone secretion	P	Any process that activates or increases the frequency, rate or extent of the regulated release of juvenile hormone.
45974	regulation of translation, ncRNA-mediated	P	Any process, mediated by small non-coding RNAs, that modulates the frequency, rate or extent that mRNAs are effectively translated into protein.
45975	positive regulation of translation, ncRNA-mediated	P	Any process, mediated by small non-coding RNAs, that activates or increases the rate that mRNAs are effectively translated into protein.
45976	negative regulation of mitotic cell cycle, embryonic	P	Any process that stops, prevents or reduces the rate or extent of progression through the embryonic mitotic cell cycle.
45977	positive regulation of mitotic cell cycle, embryonic	P	Any process that activates or increases the frequency, rate or extent of progression through the embryonic mitotic cell cycle.
45978	negative regulation of nucleoside metabolic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving nucleosides.
45979	positive regulation of nucleoside metabolic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving nucleosides.
45980	negative regulation of nucleotide metabolic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving nucleotides.
45981	positive regulation of nucleotide metabolic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving nucleotides.
45982	negative regulation of purine nucleobase metabolic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving purine nucleobases.
45983	positive regulation of purine nucleobase metabolic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving purine bases.
45984	negative regulation of pyrimidine nucleobase metabolic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving pyrimidine nucleobases.
45985	positive regulation of pyrimidine nucleobase metabolic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving pyrimidine nucleobases.
45986	negative regulation of smooth muscle contraction	P	Any process that stops, prevents, or reduces the frequency, rate or extent of smooth muscle contraction.
45987	positive regulation of smooth muscle contraction	P	Any process that activates or increases the frequency, rate or extent of smooth muscle contraction.
45988	negative regulation of striated muscle contraction	P	Any process that stops, prevents, or reduces the frequency, rate or extent of striated muscle contraction.
45989	positive regulation of striated muscle contraction	P	Any process that activates or increases the frequency, rate or extent of striated muscle contraction.
45990	carbon catabolite regulation of transcription	P	A transcription regulation process in which the presence of one carbon source leads to the modulation of the frequency, rate, or extent of transcription of specific genes involved in the metabolism of other carbon sources.
45991	carbon catabolite activation of transcription	P	A transcription regulation process in which the presence of one carbon source leads to an increase in the frequency, rate, or extent of transcription of specific genes involved in the metabolism of other carbon sources.
45992	negative regulation of embryonic development	P	Any process that stops, prevents, or reduces the frequency, rate or extent of embryonic development.
45993	negative regulation of translational initiation by iron	P	Any process involving iron that stops, prevents or reduces the rate of translational initiation.
45994	positive regulation of translational initiation by iron	P	Any process involving iron that activates or increases the rate of translational initiation.
45995	regulation of embryonic development	P	Any process that modulates the frequency, rate or extent of embryonic development.
45996	negative regulation of transcription by pheromones	P	Any process involving pheromones that stops, prevents or reduces the rate of transcription.
45997	negative regulation of ecdysteroid biosynthetic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of ecdysteroids.
45998	positive regulation of ecdysteroid biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of ecdysteroids.
45999	negative regulation of ecdysteroid secretion	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of ecdysteroid.
46000	positive regulation of ecdysteroid secretion	P	Any process that activates or increases the frequency, rate or extent of the regulated release of ecdysteroid.
46001	negative regulation of preblastoderm mitotic cell cycle	P	Any process that stops, prevents or reduces the rate or extent of progression through the preblastoderm mitotic cell cycle.
46002	positive regulation of preblastoderm mitotic cell cycle	P	Any process that activates or increases the rate or extent of progression through the preblastoderm mitotic cell cycle.
46003	negative regulation of syncytial blastoderm mitotic cell cycle	P	Any process that stops, prevents or reduces the rate or extent of progression through the syncytial blastoderm mitotic cell cycle.
46004	positive regulation of syncytial blastoderm mitotic cell cycle	P	Any process that activates or increases the rate or extent of progression through the syncytial blastoderm mitotic cell cycle.
46005	positive regulation of circadian sleep/wake cycle, REM sleep	P	Any process that activates or increases the duration or quality of rapid eye movement (REM) sleep.
46006	regulation of activated T cell proliferation	P	Any process that modulates the frequency, rate or extent of activated T cell proliferation.
46007	negative regulation of activated T cell proliferation	P	Any process that stops, prevents or reduces the rate or extent of activated T cell proliferation.
46008	regulation of female receptivity, post-mating	P	Any process that modulates the receptiveness of a female to male advances subsequent to mating.
46009	positive regulation of female receptivity, post-mating	P	Any process that increases the receptiveness of a female to male advances subsequent to mating.
46010	positive regulation of circadian sleep/wake cycle, non-REM sleep	P	Any process that activates or increases the duration or quality of non-rapid eye movement (NREM) sleep.
46011	regulation of oskar mRNA translation	P	Any process that modulates the frequency, rate or extent of oskar mRNA translation. To ensure the localization of Oskar protein at the posterior pole of the oocyte, translation of oskar mRNA is repressed during its transport to the posterior pole and activated upon localization of the mRNA at the posterior cortex.
46012	positive regulation of oskar mRNA translation	P	Any process that activates or increases the frequency, rate or extent of oskar mRNA translation.
46013	regulation of T cell homeostatic proliferation	P	Any process that modulates the frequency, rate or extent of resting T cell proliferation.
46014	negative regulation of T cell homeostatic proliferation	P	Any process that stops, prevents or reduces the rate or extent of resting T cell proliferation.
46015	regulation of transcription by glucose	P	Any process involving glucose that modulates the frequency, rate or extent or transcription.
46016	positive regulation of transcription by glucose	P	Any process involving glucose that activates or increases the rate of transcription.
46017	regulation of transcription from RNA polymerase I promoter during mitotic cell cycle	P	A cell cycle process that modulates the frequency, rate or extent of transcription from an RNA polymerase I promoter that occurs during the mitotic cell cycle.
46018	positive regulation of transcription from RNA polymerase I promoter during mitotic cell cycle	P	Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase I promoter that occurs during the mitotic cell cycle.
46019	regulation of transcription from RNA polymerase II promoter by pheromones	P	Any process involving pheromones that modulates the frequency, rate or extent or transcription from an RNA polymerase II promoter.
46020	negative regulation of transcription from RNA polymerase II promoter by pheromones	P	Any process involving pheromones that stops, prevents or reduces the rate of transcription from an RNA polymerase II promoter.
46021	regulation of transcription from RNA polymerase II promoter during mitotic cell cycle	P	A cell cycle process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that occurs during the mitotic cell cycle.
46022	positive regulation of transcription from RNA polymerase II promoter during mitotic cell cycle	P	Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter that occurs during the mitotic cell cycle.
46023	regulation of transcription from RNA polymerase III promoter during mitotic cell cycle	P	A cell cycle process that modulates the frequency, rate or extent of transcription from an RNA polymerase III promoter that occurs during the mitotic cell cycle.
46024	positive regulation of transcription from RNA polymerase III promoter during mitotic cell cycle	P	Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase III that occurs during the mitotic cell cycle.
46025	precorrin-6Y C5,15-methyltransferase (decarboxylating) activity	F	Catalysis of the reaction: 2 S-adenosyl-L-methionine + precorrin-6Y = 2 S-adenosyl-L-homocysteine + precorrin-8X + CO2.
46026	precorrin-4 C11-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + precorrin-4 = S-adenosyl-L-homocysteine + precorrin 5.
46027	phospholipid:diacylglycerol acyltransferase activity	F	Catalysis of the reaction: phospholipid + 1,2-diacylglycerol = lysophospholipid + triacylglycerol.
46028	electron transporter, transferring electrons from cytochrome b6/f complex of photosystem II activity	F	Enables the directed movement of electrons from the cytochrome b6/f complex of photosystem II.
46029	mannitol dehydrogenase activity	F	Catalysis of the reaction: D-mannitol + NAD(+) = D-mannose + H(+) + NADH.
46030	inositol trisphosphate phosphatase activity	F	Catalysis of the reaction: myo-inositol trisphosphate + H2O = myo-inositol bisphosphate + phosphate.
46031	ADP metabolic process	P	The chemical reactions and pathways involving ADP, adenosine 5'-diphosphate.
46032	ADP catabolic process	P	The chemical reactions and pathways resulting in the breakdown of ADP, adenosine 5'-diphosphate.
46033	AMP metabolic process	P	The chemical reactions and pathways involving AMP, adenosine monophosphate.
46034	ATP metabolic process	P	The chemical reactions and pathways involving ATP, adenosine triphosphate, a universally important coenzyme and enzyme regulator.
46035	CMP metabolic process	P	The chemical reactions and pathways involving CMP, cytidine monophosphate.
46036	CTP metabolic process	P	The chemical reactions and pathways involving CTP, cytidine triphosphate.
46037	GMP metabolic process	P	The chemical reactions and pathways involving GMP, guanosine monophosphate.
46038	GMP catabolic process	P	The chemical reactions and pathways resulting in the breakdown of GMP, guanosine monophosphate.
46039	GTP metabolic process	P	The chemical reactions and pathways involving GTP, guanosine triphosphate.
46040	IMP metabolic process	P	The chemical reactions and pathways involving IMP, inosine monophosphate.
46041	ITP metabolic process	P	The chemical reactions and pathways involving ITP, inosine triphosphate.
46042	ITP biosynthetic process	P	The chemical reactions and pathways resulting in the formation of ITP, inosine triphosphate.
46043	TDP metabolic process	P	The chemical reactions and pathways involving TDP, ribosylthymine diphosphate.
46044	TMP metabolic process	P	The chemical reactions and pathways involving TMP, ribosylthymine monophosphate.
46045	TMP catabolic process	P	The chemical reactions and pathways resulting in the breakdown of TMP, ribosylthymine monophosphate.
46046	TTP metabolic process	P	The chemical reactions and pathways involving TTP, ribosylthymine triphosphate.
46047	TTP catabolic process	P	The chemical reactions and pathways resulting in the breakdown of TTP, ribosylthymine triphosphate.
46048	UDP metabolic process	P	The chemical reactions and pathways involving UDP, uridine (5'-)diphosphate.
46049	UMP metabolic process	P	The chemical reactions and pathways involving UMP, uridine monophosphate.
46050	UMP catabolic process	P	The chemical reactions and pathways resulting in the breakdown of UMP, uridine monophosphate.
46051	UTP metabolic process	P	The chemical reactions and pathways involving UTP, uridine (5'-)triphosphate.
46052	UTP catabolic process	P	The chemical reactions and pathways resulting in the breakdown of UTP, uridine (5'-)triphosphate.
46053	dAMP metabolic process	P	The chemical reactions and pathways involving dAMP, deoxyadenosine monophosphate (2'-deoxyadenosine 5'-phosphate).
46054	dGMP metabolic process	P	The chemical reactions and pathways involving dGMP, deoxyguanosine monophosphate (2'-deoxyguanosine 5'-phosphate).
46055	dGMP catabolic process	P	The chemical reactions and pathways resulting in the breakdown of dGMP, deoxyguanosine monophosphate (2'-deoxyguanosine 5'-phosphate).
46056	dADP metabolic process	P	The chemical reactions and pathways involving dADP, deoxyadenosine diphosphate (2'-deoxyadenosine 5'-diphosphate).
46057	dADP catabolic process	P	The chemical reactions and pathways resulting in the breakdown of dADP, deoxyadenosine diphosphate (2'-deoxyadenosine 5'-diphosphate).
46058	cAMP metabolic process	P	The chemical reactions and pathways involving the nucleotide cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate).
46059	dAMP catabolic process	P	The chemical reactions and pathways resulting in the breakdown of dAMP, deoxyadenosine monophosphate (2'-deoxyadenosine 5'-phosphate).
46060	dATP metabolic process	P	The chemical reactions and pathways involving dATP, deoxyadenosine triphosphate (2'-deoxyadenosine 5'-triphosphate).
46061	dATP catabolic process	P	The chemical reactions and pathways resulting in the breakdown of dATP, deoxyadenosine triphosphate (2'-deoxyadenosine 5'-triphosphate).
46062	dCDP metabolic process	P	The chemical reactions and pathways involving dCDP, deoxycytidine 5'-diphosphate.
46063	dCMP metabolic process	P	The chemical reactions and pathways involving dCMP, deoxycytidine monophosphate.
46064	dCMP biosynthetic process	P	The chemical reactions and pathways resulting in the formation of dCMP, deoxycytidine monophosphate.
46065	dCTP metabolic process	P	The chemical reactions and pathways involving dCTP, deoxycytidine triphosphate.
46066	dGDP metabolic process	P	The chemical reactions and pathways involving dGDP, deoxyguanosine diphosphate, (2'-deoxyguanosine 5'-diphosphate).
46067	dGDP catabolic process	P	The chemical reactions and pathways resulting in the breakdown of dGDP, deoxyguanosine diphosphate, (2'-deoxyguanosine 5'-diphosphate).
46068	cGMP metabolic process	P	The chemical reactions and pathways involving cyclic GMP, guanosine 3',5'-phosphate.
46069	cGMP catabolic process	P	The chemical reactions and pathways resulting in the breakdown of cyclic GMP, guanosine 3',5'-phosphate.
46070	dGTP metabolic process	P	The chemical reactions and pathways involving dGTP, guanosine triphosphate.
46071	dGTP biosynthetic process	P	The chemical reactions and pathways resulting in the formation of dGTP, guanosine triphosphate.
46072	dTDP metabolic process	P	The chemical reactions and pathways involving dTDP, deoxyribosylthymine diphosphate.
46073	dTMP metabolic process	P	The chemical reactions and pathways involving dTMP, deoxyribosylthymine monophosphate (2'-deoxyribosylthymine 5'-phosphate).
46074	dTMP catabolic process	P	The chemical reactions and pathways resulting in the breakdown of dTMP, deoxyribosylthymine monophosphate.
46075	dTTP metabolic process	P	The chemical reactions and pathways involving dTTP, deoxyribosylthymine triphosphate.
46076	dTTP catabolic process	P	The chemical reactions and pathways resulting in the breakdown of dTTP, deoxyribosylthymine triphosphate.
46077	dUDP metabolic process	P	The chemical reactions and pathways involving dUDP, deoxyuridine (5'-)diphosphate.
46078	dUMP metabolic process	P	The chemical reactions and pathways involving dUMP, deoxyuridine (5'-)monophosphate (2'-deoxyuridine 5'-phosphate).
46079	dUMP catabolic process	P	The chemical reactions and pathways resulting in the breakdown of dUMP, deoxyuridine (5'-)monophosphate.
46080	dUTP metabolic process	P	The chemical reactions and pathways involving dUTP, deoxyuridine (5'-)triphosphate.
46081	dUTP catabolic process	P	The chemical reactions and pathways resulting in the breakdown of dUTP, deoxyuridine (5'-)triphosphate.
46082	5-methylcytosine biosynthetic process	P	The chemical reactions and pathways resulting in the formation of 5-methylcytosine, a methylated base of DNA.
46083	adenine metabolic process	P	The chemical reactions and pathways involving adenine, 6-aminopurine, one of the five main bases found in nucleic acids and a component of numerous important derivatives of its corresponding ribonucleoside, adenosine.
46084	adenine biosynthetic process	P	The chemical reactions and pathways resulting in the formation of adenine, 6-aminopurine, one of the five main bases found in nucleic acids and a component of numerous important derivatives of its corresponding ribonucleoside, adenosine.
46085	adenosine metabolic process	P	The chemical reactions and pathways involving adenosine, adenine riboside, a ribonucleoside found widely distributed in cells of every type as the free nucleoside and in combination in nucleic acids and various nucleoside coenzymes.
46086	adenosine biosynthetic process	P	The chemical reactions and pathways resulting in the formation of adenosine, adenine riboside, a ribonucleoside found widely distributed in cells of every type as the free nucleoside and in combination in nucleic acids and various nucleoside coenzymes.
46087	cytidine metabolic process	P	The chemical reactions and pathways involving cytidine, cytosine riboside, a widely distributed nucleoside.
46088	cytidine biosynthetic process	P	The chemical reactions and pathways resulting in the formation of cytidine, cytosine riboside, a widely distributed nucleoside.
46089	cytosine biosynthetic process	P	The chemical reactions and pathways resulting in the formation of cytosine, 4-amino-2-hydroxypyrimidine, a pyrimidine derivative that is one of the five main bases found in nucleic acids; it occurs widely in cytidine derivatives.
46090	deoxyadenosine metabolic process	P	The chemical reactions and pathways involving deoxyadenosine, 2-deoxyribosyladenine, one of the four major nucleosides of DNA.
46091	deoxyadenosine biosynthetic process	P	The chemical reactions and pathways resulting in the formation of deoxyadenosine, 2-deoxyribosyladenine, one of the four major nucleosides of DNA.
46092	deoxycytidine metabolic process	P	The chemical reactions and pathways involving deoxycytidine, 2-deoxyribosylcytosine, one of the four major nucleosides of DNA.
46093	deoxycytidine biosynthetic process	P	The chemical reactions and pathways resulting in the formation of deoxycytidine, 2-deoxyribosylcytosine, one of the four major nucleosides of DNA.
46094	deoxyinosine metabolic process	P	The chemical reactions and pathways involving deoxyinosine, hypoxanthine deoxyriboside.
46095	deoxyinosine biosynthetic process	P	The chemical reactions and pathways resulting in the formation of deoxyinosine, hypoxanthine deoxyriboside.
46096	deoxyuridine metabolic process	P	The chemical reactions and pathways involving deoxyuridine, 2-deoxyribosyluracil, one of the four major nucleosides of DNA.
46097	deoxyuridine biosynthetic process	P	The chemical reactions and pathways resulting in the formation of deoxyuridine, 2-deoxyribosyluracil, one of the four major nucleosides of DNA.
46098	guanine metabolic process	P	The chemical reactions and pathways involving guanine, 2-amino-6-hydroxypurine, a purine that is one of the five main bases found in nucleic acids and a component of a number of phosphorylated guanosine derivatives whose metabolic or regulatory functions are important.
46099	guanine biosynthetic process	P	The chemical reactions and pathways resulting in the formation of guanine, 2-amino-6-hydroxypurine, a purine that is one of the five main bases found in nucleic acids and a component of a number of phosphorylated guanosine derivatives whose metabolic or regulatory functions are important.
46100	hypoxanthine metabolic process	P	The chemical reactions and pathways involving hypoxanthine, 6-hydroxy purine, an intermediate in the degradation of adenylate. Its ribonucleoside is known as inosine and its ribonucleotide as inosinate.
46101	hypoxanthine biosynthetic process	P	The chemical reactions and pathways resulting in the formation of hypoxanthine, 6-hydroxy purine, an intermediate in the degradation of adenylate. Its ribonucleoside is known as inosine and its ribonucleotide as inosinate.
46102	inosine metabolic process	P	The chemical reactions and pathways involving inosine, hypoxanthine riboside, a nucleoside found free but not in combination in nucleic acids except in the anticodons of some tRNAs.
46103	inosine biosynthetic process	P	The chemical reactions and pathways resulting in the formation of inosine, hypoxanthine riboside, a nucleoside found free but not in combination in nucleic acids except in the anticodons of some tRNAs.
46104	thymidine metabolic process	P	The chemical reactions and pathways involving thymidine, deoxyribosylthymine thymine 2-deoxyriboside, a deoxynucleoside very widely distributed but occurring almost entirely as phosphoric esters in deoxynucleotides and deoxyribonucleic acid, DNA.
46105	thymidine biosynthetic process	P	The chemical reactions and pathways resulting in the formation of thymidine, deoxyribosylthymine thymine 2-deoxyriboside, a deoxynucleoside very widely distributed but occurring almost entirely as phosphoric esters in deoxynucleotides and deoxyribonucleic acid, DNA.
46106	thymine biosynthetic process	P	The chemical reactions and pathways resulting in the formation of thymine, 5-methyluracil, one of the two major pyrimidine bases present (as thymidine) in DNA but not found in RNA other than (as ribothymidine) in transfer RNA, where it is a minor base.
46107	uracil biosynthetic process	P	The chemical reactions and pathways resulting in the formation of uracil, 2,4-dioxopyrimidine, one of the pyrimidine bases occurring in RNA, but not in DNA.
46108	uridine metabolic process	P	The chemical reactions and pathways involving uridine, uracil riboside, a ribonucleoside very widely distributed but occurring almost entirely as phosphoric esters in ribonucleotides and ribonucleic acids.
46109	uridine biosynthetic process	P	The chemical reactions and pathways resulting in the formation of uridine, uracil riboside, a ribonucleoside very widely distributed but occurring almost entirely as phosphoric esters in ribonucleotides and ribonucleic acids.
46110	xanthine metabolic process	P	The chemical reactions and pathways involving xanthine, 2,6-dihydroxypurine, a purine formed in the metabolic breakdown of guanine but not present in nucleic acids.
46111	xanthine biosynthetic process	P	The chemical reactions and pathways resulting in the formation of xanthine, 2,6-dihydroxypurine, a purine formed in the metabolic breakdown of guanine but not present in nucleic acids.
46112	nucleobase biosynthetic process	P	The chemical reactions and pathways resulting in the formation of a nucleobase, a nitrogenous base that is a constituent of a nucleic acid.
46113	nucleobase catabolic process	P	The chemical reactions and pathways resulting in the breakdown of a nucleobase, a nitrogenous base that is a constituent of a nucleic acid.
46114	guanosine biosynthetic process	P	The chemical reactions and pathways resulting in the formation of guanine, guanine riboside, a nucleoside with a wide species distribution.
46115	guanosine catabolic process	P	The chemical reactions and pathways resulting in the breakdown of guanine, guanine riboside, a nucleoside with a wide species distribution.
46116	queuosine metabolic process	P	The chemical reactions and pathways involving queuosines, any of a series of nucleosides found in tRNA and having an additional pentenyl ring added via an NH group to the methyl group of 7-methylguanosine. The pentenyl ring may carry other substituents.
46117	queuosine catabolic process	P	The chemical reactions and pathways resulting in the breakdown of queuosines, any of a series of nucleosides found in tRNA and having an additional pentenyl ring added via an NH group to the methyl group of 7-methylguanosine. The pentenyl ring may carry other substituents.
46118	7-methylguanosine biosynthetic process	P	The chemical reactions and pathways resulting in the formation of 7-methylguanosine, a modified nucleoside that forms a cap at the 5'-terminus of eukaryotic mRNA.
46119	7-methylguanosine catabolic process	P	The chemical reactions and pathways resulting in the breakdown of 7-methylguanosine, a modified nucleoside that forms a cap at the 5'-terminus of eukaryotic mRNA.
46120	deoxyribonucleoside biosynthetic process	P	The chemical reactions and pathways resulting in the formation of any one of a family of organic molecules consisting of a purine or pyrimidine base covalently bonded to a sugar deoxyribose (a deoxyribonucleoside).
46121	deoxyribonucleoside catabolic process	P	The chemical reactions and pathways resulting in the breakdown of any one of a family of organic molecules consisting of a purine or pyrimidine base covalently bonded to a sugar deoxyribose (a deoxyribonucleoside).
46122	purine deoxyribonucleoside metabolic process	P	The chemical reactions and pathways involving any one of a family of organic molecules consisting of a purine base covalently bonded to a sugar deoxyribose (a deoxyribonucleoside).
46123	purine deoxyribonucleoside biosynthetic process	P	The chemical reactions and pathways resulting in the formation of any purine deoxyribonucleoside, one of a family of organic molecules consisting of a purine base covalently bonded to a sugar deoxyribose (a deoxyribonucleoside).
46124	purine deoxyribonucleoside catabolic process	P	The chemical reactions and pathways resulting in the breakdown of any one of a family of organic molecules consisting of a purine base covalently bonded to a sugar deoxyribose (a deoxyribonucleoside).
46125	pyrimidine deoxyribonucleoside metabolic process	P	The chemical reactions and pathways involving any one of a family of organic molecules consisting of a pyrimidine base covalently bonded to a sugar deoxyribose (a deoxyribonucleoside).
46126	pyrimidine deoxyribonucleoside biosynthetic process	P	The chemical reactions and pathways resulting in the formation of any one of a family of organic molecules consisting of a pyrimidine base covalently bonded to a sugar deoxyribose (a deoxyribonucleoside).
46127	pyrimidine deoxyribonucleoside catabolic process	P	The chemical reactions and pathways resulting in the breakdown of any one of a family of organic molecules consisting of a pyrimidine base covalently bonded to a sugar deoxyribose (a deoxyribonucleoside).
46128	purine ribonucleoside metabolic process	P	The chemical reactions and pathways involving any ribonucleoside, a nucleoside in which purine base is linked to a ribose (beta-D-ribofuranose) molecule.
46129	purine ribonucleoside biosynthetic process	P	The chemical reactions and pathways resulting in the formation of any purine ribonucleoside, a nucleoside in which purine base is linked to a ribose (beta-D-ribofuranose) molecule.
46130	purine ribonucleoside catabolic process	P	The chemical reactions and pathways resulting in the breakdown of any purine ribonucleoside, a nucleoside in which purine base is linked to a ribose (beta-D-ribofuranose) molecule.
46131	pyrimidine ribonucleoside metabolic process	P	The chemical reactions and pathways involving any ribonucleoside, a nucleoside in which pyrimidine base is linked to a ribose (beta-D-ribofuranose) molecule.
46132	pyrimidine ribonucleoside biosynthetic process	P	The chemical reactions and pathways resulting in the formation of any ribonucleoside, a nucleoside in which a pyrimidine base is linked to a ribose (beta-D-ribofuranose) molecule.
46133	pyrimidine ribonucleoside catabolic process	P	The chemical reactions and pathways resulting in the breakdown of any ribonucleoside, a nucleoside in which a pyrimidine base is linked to a ribose (beta-D-ribofuranose) molecule.
46134	pyrimidine nucleoside biosynthetic process	P	The chemical reactions and pathways resulting in the formation of one of a family of organic molecules consisting of a pyrimidine base covalently bonded to a sugar ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside).
46135	pyrimidine nucleoside catabolic process	P	The chemical reactions and pathways resulting in the breakdown of one of a family of organic molecules consisting of a pyrimidine base covalently bonded to a sugar ribose (a ribonucleoside) or deoxyribose (a deoxyribonucleoside).
46136	positive regulation of vitamin metabolic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving a vitamin, one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body.
46137	negative regulation of vitamin metabolic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving a vitamin, one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body.
46140	corrin biosynthetic process	P	The chemical reactions and pathways resulting in the formation of corrin, C19H22N4, the fundamental heterocyclic skeleton of the corrinoids. It consists of four reduced pyrrole rings joined into a macrocyclic ring. Corrin is the core of the vitamin B12 molecule.
46141	corrin catabolic process	P	The chemical reactions and pathways resulting in the breakdown of corrin, C19H22N4, the fundamental heterocyclic skeleton of the corrinoids. It consists of four reduced pyrrole rings joined into a macrocyclic ring. Corrin is the core of the vitamin B12 molecule.
46144	D-alanine family amino acid metabolic process	P	The chemical reactions and pathways involving D-alanine and related amino acids.
46145	D-alanine family amino acid biosynthetic process	P	The chemical reactions and pathways resulting in the formation of D-alanine and related amino acids.
46146	tetrahydrobiopterin metabolic process	P	The chemical reactions and pathways involving tetrahydrobiopterin, the reduced form of biopterin (2-amino-4-hydroxy-6-(1,2-dihydroxypropyl)-pteridine). It functions as a hydroxylation coenzyme, e.g. in the conversion of phenylalanine to tyrosine.
46147	tetrahydrobiopterin catabolic process	P	The chemical reactions and pathways resulting in the breakdown of tetrahydrobiopterin, the reduced form of biopterin (2-amino-4-hydroxy-6-(1,2-dihydroxypropyl)-pteridine). It functions as a hydroxylation coenzyme, e.g. in the conversion of phenylalanine to tyrosine.
46148	pigment biosynthetic process	P	The chemical reactions and pathways resulting in the formation of a pigment, any general or particular coloring matter in living organisms, e.g. melanin.
46149	pigment catabolic process	P	The chemical reactions and pathways resulting in the breakdown of a pigment, any general or particular coloring matter in living organisms, e.g. melanin.
46150	melanin catabolic process	P	The chemical reactions and pathways resulting in the breakdown of melanins, pigments largely of animal origin. High molecular weight polymers of indole quinone, they are irregular polymeric structures and are divided into three groups: allomelanins in the plant kingdom and eumelanins and phaeomelanins in the animal kingdom.
46151	eye pigment catabolic process	P	The chemical reactions and pathways resulting in the breakdown of eye pigments, any general or particular coloring matter in living organisms, found or utilized in the eye.
46152	ommochrome metabolic process	P	The chemical reactions and pathways involving ommochromes, any of a large group of natural polycyclic pigments commonly found in the Arthropoda, particularly in the ommatidia of the compound eye.
46153	ommochrome catabolic process	P	The chemical reactions and pathways resulting in the breakdown of ommochromes, any of a large group of natural polycyclic pigments commonly found in the Arthropoda, particularly in the ommatidia of the compound eye.
46154	rhodopsin metabolic process	P	The chemical reactions and pathways involving rhodopsin, a brilliant purplish-red, light-sensitive visual pigment found in the rod cells of the retinas.
46155	rhodopsin catabolic process	P	The chemical reactions and pathways resulting in the breakdown of rhodopsin, a brilliant purplish-red, light-sensitive visual pigment found in the rod cells of the retinas.
46156	siroheme metabolic process	P	The chemical reactions and pathways involving siroheme, a tetrahydroporphyrin with adjacent, reduced pyrrole rings.
46157	siroheme catabolic process	P	The chemical reactions and pathways resulting in the breakdown of siroheme, a tetrahydroporphyrin with adjacent, reduced pyrrole rings.
46158	ocellus pigment metabolic process	P	The chemical reactions and pathways involving ocellus pigments, any general or particular coloring matter in living organisms, found or utilized in the ocellus, a minute simple eye found in many invertebrates.
46159	ocellus pigment catabolic process	P	The chemical reactions and pathways resulting in the breakdown of ocellus pigments, any general or particular coloring matter in living organisms, found or utilized in the ocellus, a minute simple eye found in many invertebrates.
46160	heme a metabolic process	P	The chemical reactions and pathways involving heme a, a derivative of heme found in cytochrome aa3.
46161	heme a catabolic process	P	The chemical reactions and pathways resulting in the breakdown of heme a, a derivative of heme found in cytochrome aa3.
46162	heme c metabolic process	P	The chemical reactions and pathways involving heme c, a derivative of heme found in cytochromes c, b4, and f.
46163	heme c catabolic process	P	The chemical reactions and pathways resulting in the breakdown of heme c, a derivative of heme found in cytochromes c, b4, and f.
46164	alcohol catabolic process	P	The chemical reactions and pathways resulting in the breakdown of alcohols, any of a class of compounds containing one or more hydroxyl groups attached to a saturated carbon atom.
46165	alcohol biosynthetic process	P	The chemical reactions and pathways resulting in the formation of alcohols, any of a class of compounds containing one or more hydroxyl groups attached to a saturated carbon atom.
46166	glyceraldehyde-3-phosphate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of glyceraldehyde-3-phosphate, an important intermediate in glycolysis.
46167	glycerol-3-phosphate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of glycerol-3-phosphate, a phosphoric monoester of glycerol.
46168	glycerol-3-phosphate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of glycerol-3-phosphate, a phosphoric monoester of glycerol.
46169	methanol biosynthetic process	P	The chemical reactions and pathways resulting in the formation of methanol, CH3-OH, a colorless, flammable, mobile, poisonous liquid, widely used as a solvent.
46170	methanol catabolic process	P	The chemical reactions and pathways resulting in the breakdown of methanol, CH3-OH, a colorless, flammable, mobile, poisonous liquid, widely used as a solvent.
46171	octanol biosynthetic process	P	The chemical reactions and pathways resulting in the formation of octanol, the 8-carbon alcohol with the formula C8H17OH.
46172	octanol catabolic process	P	The chemical reactions and pathways resulting in the breakdown of octanol, the 8-carbon alcohol with the formula C8H17OH.
46173	polyol biosynthetic process	P	The chemical reactions and pathways resulting in the formation of a polyol, any alcohol containing three or more hydroxyl groups attached to saturated carbon atoms.
46174	polyol catabolic process	P	The chemical reactions and pathways resulting in the breakdown of a polyol, any alcohol containing three or more hydroxyl groups attached to saturated carbon atoms.
46175	aldonic acid biosynthetic process	P	The chemical reactions and pathways resulting in the formation of aldonic acid, a monocarboxylic acid with a chain of three or more carbon atoms, derived from an aldose by oxidation of the aldehydic group.
46176	aldonic acid catabolic process	P	The chemical reactions and pathways resulting in the breakdown of aldonic acid, a monocarboxylic acid with a chain of three or more carbon atoms, derived from an aldose by oxidation of the aldehydic group.
46177	D-gluconate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of D-gluconate, the anion of D-gluconic acid, the aldonic acid derived from glucose.
46178	D-gluconate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of D-gluconate, the anion of D-gluconic acid, the aldonic acid derived from glucose.
46179	keto-D-gluconate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of keto-D-gluconate, the anion of keto-D-gluconic acid, an aldonic acid derived from glucose.
46180	ketogluconate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of ketogluconate, the anion of ketogluconic acid, an aldonic acid derived from glucose containing a ketonic carbonyl group.
46181	ketogluconate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of ketogluconate, the anion of ketogluconic acid, an aldonic acid derived from glucose containing a ketonic carbonyl group.
46182	L-idonate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of L-idonate, the anion of idonic acid, an aldonic acid derived from L-idose, an aldohexose which is epimeric with D-glucose.
46183	L-idonate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of L-idonate, the anion of idonic acid, an aldonic acid derived from L-idose, an aldohexose which is epimeric with D-glucose.
46184	aldehyde biosynthetic process	P	The chemical reactions and pathways resulting in the formation of aldehydes, any organic compound with the formula R-CH=O.
46185	aldehyde catabolic process	P	The chemical reactions and pathways resulting in the breakdown of aldehydes, any organic compound with the formula R-CH=O.
46186	acetaldehyde biosynthetic process	P	The chemical reactions and pathways resulting in the formation of acetaldehyde, a colorless, flammable liquid intermediate in the metabolism of alcohol.
46187	acetaldehyde catabolic process	P	The chemical reactions and pathways resulting in the breakdown of acetaldehyde, a colorless, flammable liquid intermediate in the metabolism of alcohol.
46188	methane catabolic process	P	The chemical reactions and pathways resulting in the breakdown of methane, a colorless, odorless, flammable gas with the formula CH4. It is the simplest of the alkanes.
46189	phenol-containing compound biosynthetic process	P	The chemical reactions and pathways resulting in the formation of a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring.
46190	aerobic phenol-containing compound biosynthetic process	P	The chemical reactions and pathways resulting in the formation of a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring, in the presence of oxygen.
46191	aerobic phenol-containing compound catabolic process	P	The chemical reactions and pathways resulting in the breakdown of a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring, in the presence of oxygen.
46192	anaerobic phenol-containing compound biosynthetic process	P	The chemical reactions and pathways resulting in the formation of a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring, in the absence of oxygen.
46193	anaerobic phenol-containing compound catabolic process	P	The chemical reactions and pathways resulting in the breakdown of a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring, in the absence of oxygen.
46196	4-nitrophenol catabolic process	P	The chemical reactions and pathways resulting in the breakdown of 4-nitrophenol, a nitroaromatic compound which is used in the production of dyes, leather treatment agents, fungicides and as an intermediate in the production of the insecticide parathion.
46197	orcinol biosynthetic process	P	The chemical reactions and pathways resulting in the formation of orcinol (5-methyl-1,3-benzenediol), an aromatic compound derived from the fermentation of lichen and synthesized by some higher plants.
46199	cresol catabolic process	P	The chemical reactions and pathways resulting in the breakdown of cresol, a mixture of the aromatic alcohol isoforms o-, p-, and m-cresol, which is obtained from coal tar or petroleum. The isomers are used as disinfectants, textile scouring agents, surfactants and as intermediates in the manufacture of salicylaldehyde, coumarin, and herbicides as well as being a major component of creosote.
46201	cyanate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of cyanate, NCO-, the anion of cyanic acid.
46202	cyanide biosynthetic process	P	The chemical reactions and pathways resulting in the formation of cyanide, NC-, the anion of hydrocyanic acid. Cyanide is a potent inhibitor of respiration.
46203	spermidine catabolic process	P	The chemical reactions and pathways resulting in the breakdown of spermidine, N-(3-aminopropyl)-1,4-diaminobutane.
46204	nor-spermidine metabolic process	P	The chemical reactions and pathways involving nor-spermidine, a compound related to spermidine, N-(3-aminopropyl)-1,4-diaminobutane.
46205	nor-spermidine catabolic process	P	The chemical reactions and pathways resulting in the breakdown of nor-spermidine, a compound related to spermidine, N-(3-aminopropyl)-1,4-diaminobutane.
46206	trypanothione metabolic process	P	The chemical reactions and pathways involving trypanothione (N1,N6,-bis(glutathionyl)spermidine), an essential redox intermediate in intracellular thiol redox regulation which also plays a role in protecting against oxidative stress.
46207	trypanothione catabolic process	P	The chemical reactions and pathways resulting in the breakdown of trypanothione (N1,N6,-bis(glutathionyl)spermidine), an essential redox intermediate in intracellular thiol redox regulation which also plays a role in protecting against oxidative stress.
46208	spermine catabolic process	P	The chemical reactions and pathways resulting in the breakdown of spermine, a polybasic amine found in human sperm, in ribosomes and in some viruses and involved in nucleic acid packaging.
46209	nitric oxide metabolic process	P	The chemical reactions and pathways involving nitric oxide, nitrogen monoxide (NO), a colorless gas only slightly soluble in water.
46210	nitric oxide catabolic process	P	The chemical reactions and pathways resulting in the breakdown of nitric oxide, nitrogen monoxide (NO), a colorless gas only slightly soluble in water.
46211	(+)-camphor biosynthetic process	P	The chemical reactions and pathways resulting in the formation of (+)-camphor, a bicyclic monoterpene ketone.
46213	methyl ethyl ketone catabolic process	P	The chemical reactions and pathways resulting in the breakdown of methyl ethyl ketone, a clear, colorless liquid with a fragrant, mint-like odor.
46214	enterobactin catabolic process	P	The chemical reactions and pathways resulting in the breakdown of enterobactin, a catechol-derived siderochrome of Enterobacteria; enterobactin (N',N',N''-(2,6,10-trioxo-1,5,9-triacyclodecane-3,7,11-triyl)tris(2,3-dihydroxy)benzamide) is a self-triester of 2,3-dihydroxy-N-benzoyl-L-serine and a product of the shikimate pathway.
46215	siderophore catabolic process	P	The chemical reactions and pathways resulting in the breakdown of siderophores, low molecular weight Fe(III)-chelating substances made by aerobic or facultatively anaerobic bacteria, especially when growing under iron deficient conditions. The complexes of Fe(3+)-siderophores have very high stability constants and are taken up by specific transport systems by microorganisms; the subsequent release of iron requires enzymatic action.
46216	indole phytoalexin catabolic process	P	The chemical reactions and pathways resulting in the breakdown of indole phytoalexins, any indole compound produced by plants as part of their defense response.
46217	indole phytoalexin metabolic process	P	The chemical reactions and pathways involving indole phytoalexins, any indole compound produced by plants as part of their defense response.
46218	indolalkylamine catabolic process	P	The chemical reactions and pathways resulting in the breakdown of indolalkylamines, indole or indole derivatives containing a primary, secondary, or tertiary amine group.
46219	indolalkylamine biosynthetic process	P	The chemical reactions and pathways resulting in the formation of indolalkylamines, indole or indole derivatives containing a primary, secondary, or tertiary amine group.
46220	pyridine biosynthetic process	P	The chemical reactions and pathways resulting in the formation of pyridine, a nitrogenous base (C5H5N) obtained from the distillation of bone oil or coal tar, and by the decomposition of certain alkaloids, as a colorless liquid with a peculiar pungent odor.
46221	pyridine catabolic process	P	The chemical reactions and pathways resulting in the breakdown of pyridine, a nitrogenous base (C5H5N) obtained from the distillation of bone oil or coal tar, and by the decomposition of certain alkaloids, as a colorless liquid with a peculiar pungent odor.
46222	aflatoxin metabolic process	P	The chemical reactions and pathways involving aflatoxin, a fungal metabolite found as a contaminant in moldy grains that induces liver cancer. Aflatoxin induces a G to T transversion at codon 249 of p53, leading to its inactivation. Aflatoxin is converted to a chemical carcinogen by P450.
46223	aflatoxin catabolic process	P	The chemical reactions and pathways resulting in the breakdown of aflatoxin, a fungal metabolite found as a contaminant in moldy grains that induces liver cancer. Aflatoxin induces a G to T transversion at codon 249 of p53, leading to its inactivation. Aflatoxin is converted to a chemical carcinogen by P450.
46224	bacteriocin metabolic process	P	The chemical reactions and pathways involving bacteriocins, any of a heterogeneous group of polypeptide antibiotics that are secreted by certain bacterial strains and are able to kill cells of other susceptible (frequently related) strains after adsorption at specific receptors on the cell surface. They include the colicins, and their mechanisms of action vary.
46225	bacteriocin catabolic process	P	The chemical reactions and pathways resulting in the breakdown of a bacteriocin, any of a heterogeneous group of polypeptide antibiotics that are secreted by certain bacterial strains and are able to kill cells of other susceptible (frequently related) strains after adsorption at specific receptors on the cell surface. They include the colicins, and their mechanisms of action vary.
46226	coumarin catabolic process	P	The chemical reactions and pathways resulting in the breakdown of coumarins, compounds derived from the phenylacrylic skeleton of cinnamic acids.
46228	2,4,5-trichlorophenoxyacetic acid catabolic process	P	The chemical reactions and pathways resulting in the breakdown of 2,4,5-trichlorophenoxyacetic acid, a chlorinated aromatic compound widely used as a herbicide.
46230	2-aminobenzenesulfonate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of 2-aminobenzenesulfonate, an aromatic sulfonate used in organic synthesis and in the manufacture of various dyes and medicines.
46232	carbazole catabolic process	P	The chemical reactions and pathways resulting in the breakdown of carbazole, a heterocyclic aromatic compound containing a dibenzopyrrole system that is produced during coal gasification and is present in cigarette smoke. Coal tar produced at high temperature contains an average of 1.5% carbazole. It is used widely in synthesis of dyes, pharmaceuticals, and plastics and is a suspected carcinogen.
46235	gallate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of gallate, the anion of gallic acid (3,4,5-trihydroxybenzoic acid).
46236	mandelate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of mandelate, the anion of mandelic acid. Mandelic acid (alpha-hydroxybenzeneacetic acid) is an 8-carbon alpha-hydroxy acid (AHA) that is used in organic chemistry and as a urinary antiseptic.
46239	phthalate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of phthalate, the anion of phthalic acid.
46244	salicylic acid catabolic process	P	The chemical reactions and pathways resulting in the breakdown of salicylic acid (2-hydroxybenzoic acid), a derivative of benzoic acid.
46246	terpene biosynthetic process	P	The chemical reactions and pathways resulting in the formation of terpenes, any of a large group of hydrocarbons made up of isoprene units.
46247	terpene catabolic process	P	The chemical reactions and pathways resulting in the breakdown of terpenes, any of a large group of hydrocarbons made up of isoprene units.
46248	alpha-pinene biosynthetic process	P	The chemical reactions and pathways resulting in the formation of alpha-pinene, a monoterpene that may be a significant factor affecting bacterial activities in nature.
46249	alpha-pinene catabolic process	P	The chemical reactions and pathways resulting in the breakdown of alpha-pinene, a monoterpene that may be a significant factor affecting bacterial activities in nature.
46250	limonene biosynthetic process	P	The chemical reactions and pathways resulting in the formation of limonene (4-isopropenyl-1-methyl-cyclohexene), a monocyclic monoterpene.
46251	limonene catabolic process	P	The chemical reactions and pathways resulting in the breakdown of limonene (4-isopropenyl-1-methyl-cyclohexene), a monocyclic monoterpene.
46252	toluene biosynthetic process	P	The chemical reactions and pathways resulting in the formation of toluene, a volatile monoaromatic hydrocarbon found in crude petroleum and petroleum products.
46253	anaerobic toluene biosynthetic process	P	The chemical reactions and pathways resulting in the formation of toluene, a volatile monoaromatic hydrocarbon found in crude petroleum and petroleum products, in the absence of oxygen.
46254	anaerobic toluene catabolic process	P	The chemical reactions and pathways resulting in the breakdown of toluene, a volatile monoaromatic hydrocarbon found in crude petroleum and petroleum products, in the absence of oxygen.
46256	2,4,6-trinitrotoluene catabolic process	P	The chemical reactions and pathways resulting in the breakdown of 2,4,6-trinitrotoluene, 1-methyl-2,4,6-trinitrobenzene, a highly explosive pale yellow crystalline solid.
46258	anaerobic 2,4,6-trinitrotoluene catabolic process	P	The chemical reactions and pathways resulting in the breakdown of 2,4,6-trinitrotoluene, 1-methyl-2,4,6-trinitrobenzene, a highly explosive pale yellow crystalline solid, in the absence of oxygen.
46260	trinitrotoluene catabolic process	P	The chemical reactions and pathways resulting in the breakdown of trinitrotoluene, a methylated benzene entity with three NO2 groups attached to it. This includes the explosive TNT, 1-methyl-2,4,6-trinitrobenzene.
46263	nitrotoluene catabolic process	P	The chemical reactions and pathways resulting in the breakdown of nitrotoluene, any methylbenzene molecule with NO2 group(s) attached.
46265	thiocyanate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of thiocyanate, any anion of thiocyanic acid.
46267	triethanolamine catabolic process	P	The chemical reactions and pathways resulting in the breakdown of triethanolamine, a combustible, hygroscopic, colorless liquid commonly used in dry-cleaning solutions, cosmetics, detergents, textile processing, wool scouring, and as a corrosion inhibitor and pharmaceutical alkalizing agent.
46269	toluene-4-sulfonate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of toluene-4-sulfonate, 4-methylbenzenesulfonate, the anion of sulfonic acid attached to a methylbenzene molecule.
46271	phenylpropanoid catabolic process	P	The chemical reactions and pathways resulting in the breakdown of aromatic derivatives of trans-cinnamic acid.
46272	stilbene catabolic process	P	The chemical reactions and pathways resulting in the breakdown of stilbenes, a class of polyketide compounds formed from cinnamic acid and three molecules of malonyl CoA.
46273	lignan catabolic process	P	The chemical reactions and pathways resulting in the breakdown of lignans, any member of a class of plant metabolites related to lignins. Lignans are usually found as phenylpropanoid dimers in which the phenylpropanoid units are linked tail to tail and thus having a 2,3 dibenzylbutane skeleton, but higher oligomers can also exist.
46274	lignin catabolic process	P	The chemical reactions and pathways resulting in the breakdown of lignins, a class of polymers of phenylpropanoid units.
46275	flavonoid catabolic process	P	The chemical reactions and pathways resulting in the breakdown of flavonoids, a group of phenolic derivatives containing a flavan skeleton.
46276	methylgallate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of methylgallate, trihydroxymethylbenzoate, the anion of methylgallic acid.
46277	methylgallate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of methylgallate, trihydroxymethylbenzoate, the anion of methylgallic acid.
46278	3,4-dihydroxybenzoate metabolic process	P	The chemical reactions and pathways involving protocatechuate, the anion of protocatechuic acid (3,4-dihydroxybenzoic acid).
46279	3,4-dihydroxybenzoate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of 3,4-dihydroxybenzoate.
46280	chalcone catabolic process	P	The chemical reactions and pathways resulting in the breakdown of chalcone, phenyl steryl ketone or its hydroxylated derivatives.
46281	cinnamic acid catabolic process	P	The chemical reactions and pathways resulting in the breakdown of cinnamic acid, 3-phenyl-2-propenoic acid.
46282	cinnamic acid ester catabolic process	P	The chemical reactions and pathways resulting in the breakdown of ester derivatives of cinnamic acid, phenylpropenoic acid.
46283	anthocyanin-containing compound metabolic process	P	The chemical reactions and pathways involving anthocyanins, any member of a group of intensely colored soluble glycosides of anthocyanidins that occur in plants. They are responsible from most of the scarlet, purple, mauve and blue coloring in higher plants, especially of flowers.
46284	anthocyanin-containing compound catabolic process	P	The chemical reactions and pathways resulting in the breakdown of anthocyanins, any member of a group of intensely colored soluble glycosides of anthocyanidins.
46285	flavonoid phytoalexin metabolic process	P	The chemical reactions and pathways involving flavonoid phytoalexins, a group of water-soluble phenolic derivatives containing a flavan skeleton, which possess antibiotic activity and are produced by plant tissues in response to infection.
46286	flavonoid phytoalexin catabolic process	P	The chemical reactions and pathways resulting in the breakdown of flavonoid phytoalexins, a group of water-soluble phenolic derivatives containing a flavan skeleton, which possess antibiotic activity and are produced by plant tissues in response to infection.
46287	isoflavonoid metabolic process	P	The chemical reactions and pathways involving isoflavonoids, a group of water-soluble phenolic derivatives, isomeric with flavonoids, containing a flavan skeleton. They are differentiated from flavonoids by the point of attachment of the aromatic ring group.
46288	isoflavonoid catabolic process	P	The chemical reactions and pathways resulting in the breakdown of isoflavonoids, a group of water-soluble phenolic derivatives, isomeric with flavonoids.
46289	isoflavonoid phytoalexin metabolic process	P	The chemical reactions and pathways involving isoflavonoid phytoalexins, a group of water-soluble phenolic derivatives isomeric with flavonoids that possess antibiotic activity and are produced by plant tissues in response to infection.
46290	isoflavonoid phytoalexin catabolic process	P	The chemical reactions and pathways resulting in the breakdown of isoflavonoid phytoalexins, a group of water-soluble phenolic derivatives isomeric with flavonoids that possess antibiotic activity and are produced by plant tissues in response to infection.
46292	formaldehyde metabolic process	P	The chemical reactions and pathways involving formaldehyde (methanal, H2C=O), a colorless liquid or gas with a pungent odor, commonly used as a fixative or an antibacterial agent.
46293	formaldehyde biosynthetic process	P	The chemical reactions and pathways resulting in the formation of formaldehyde (methanal, H2C=O), the simplest aldehyde.
46294	formaldehyde catabolic process	P	The chemical reactions and pathways resulting in the breakdown of formaldehyde (methanal, H2C=O), the simplest aldehyde.
46295	glycolate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of glycolate, the anion of hydroxyethanoic acid (glycolic acid).
46296	glycolate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of glycolate, the anion of hydroxyethanoic acid (glycolic acid).
46298	2,4-dichlorobenzoate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of 2,4-dichlorobenzoate, a chlorinated aromatic compound which is a key intermediate in the aerobic degradation of polychlorinated biphenyls (PCBs).
46300	2,4-dichlorophenoxyacetic acid catabolic process	P	The chemical reactions and pathways resulting in the breakdown of 2,4-dichlorophenoxyacetic acid, a chlorinated phenoxy compound which functions as a systemic herbicide and is used to control many types of broadleaf weeds.
46302	2-chloro-N-isopropylacetanilide catabolic process	P	The chemical reactions and pathways resulting in the breakdown of 2-chloro-N-isopropylacetanilide, an acylanide herbicide widely used to protect corn, onion, cabbage, rose bushes, and ornamental plants.
46304	2-nitropropane catabolic process	P	The chemical reactions and pathways resulting in the breakdown of 2-nitropropane, a clear, colorless liquid with a mild, fruity odor.
46305	alkanesulfonate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of alkanesulfonates, the anion of alkanesulfonic acids, sulfonic acid derivatives containing an aliphatic hydrocarbon group.
46306	alkanesulfonate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of alkanesulfonates, the anion of alkanesulfonic acids, sulfonic acid derivatives containing an aliphatic hydrocarbon group.
46307	Z-phenylacetaldoxime biosynthetic process	P	The chemical reactions and pathways resulting in the formation of Z-phenylacetaldoxime, a member of the glucosinolate group of compounds.
46308	Z-phenylacetaldoxime catabolic process	P	The chemical reactions and pathways resulting in the breakdown of Z-phenylacetaldoxime, a member of the glucosinolate group of compounds.
46309	1,3-dichloro-2-propanol biosynthetic process	P	The chemical reactions and pathways resulting in the formation of 1,3-dichloro-2-propanol (DCP), a halohydrin suspected of being carcinogenic, mutagenic and genotoxic.
46310	1,3-dichloro-2-propanol catabolic process	P	The chemical reactions and pathways resulting in the breakdown of 1,3-dichloro-2-propanol (DCP), a halohydrin suspected of being carcinogenic, mutagenic and genotoxic.
46311	prenylcysteine biosynthetic process	P	The chemical reactions and pathways resulting in the formation of prenylcysteine, 3-methyl-2-buten-1-yl-cysteine, a derivative of the amino acid cysteine formed by the covalent addition of a prenyl residue.
46312	phosphoarginine biosynthetic process	P	The chemical reactions and pathways resulting in the formation of phosphoarginine, a phosphorylated derivative of the amino acid arginine.
46313	phosphoarginine catabolic process	P	The chemical reactions and pathways resulting in the breakdown of phosphoarginine, a phosphorylated derivative of the amino acid arginine.
46314	phosphocreatine biosynthetic process	P	The chemical reactions and pathways resulting in the formation of phosphocreatine, a phosphagen of creatine which is synthesized and broken down by creatine phosphokinase.
46315	phosphocreatine catabolic process	P	The chemical reactions and pathways resulting in the breakdown of phosphocreatine, a phosphagen of creatine which is synthesized and broken down by creatine phosphokinase.
46316	gluconokinase activity	F	Catalysis of the reaction: D-gluconate + ATP = 6-phospho-D-gluconate + ADP + 2 H(+).
46317	regulation of glucosylceramide biosynthetic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glucosylceramide.
46318	negative regulation of glucosylceramide biosynthetic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glucosylceramide.
46319	positive regulation of glucosylceramide biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glucosylceramide.
46320	regulation of fatty acid oxidation	P	Any process that modulates the frequency, rate or extent of fatty acid oxidation.
46321	positive regulation of fatty acid oxidation	P	Any process that activates or increases the frequency, rate or extent of fatty acid oxidation.
46322	negative regulation of fatty acid oxidation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of fatty acid oxidation.
46323	glucose import	P	The directed movement of the hexose monosaccharide glucose into a cell or organelle.
46324	regulation of glucose import	P	Any process that modulates the frequency, rate or extent of the import of the hexose monosaccharide glucose into a cell or organelle.
46325	negative regulation of glucose import	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the import of the hexose monosaccharide glucose into a cell or organelle.
46326	positive regulation of glucose import	P	Any process that activates or increases the frequency, rate or extent of the import of the hexose monosaccharide glucose into a cell or organelle.
46327	glycerol biosynthetic process from pyruvate	P	The chemical reactions and pathways resulting in the formation of glycerol, 1,2,3-propanetriol, from other compounds, including pyruvate.
46328	regulation of JNK cascade	P	Any process that modulates the frequency, rate or extent of signal transduction mediated by the JNK cascade.
46329	negative regulation of JNK cascade	P	Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the JNK cascade.
46330	positive regulation of JNK cascade	P	Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the JNK cascade.
46331	lateral inhibition	P	Signaling between cells of equivalent developmental potential that results in these cells adopting different developmental fates. An example is the suppression by cells with a particular fate of the adoption of the same fate by surrounding cells.
46332	SMAD binding	F	Interacting selectively and non-covalently with a SMAD signaling protein.
46333	octopamine metabolic process	P	The chemical reactions and pathways involving octopamine, 1-(p-hydroxyphenyl)-2-aminoethanol. The D enantiomer is about one-tenth as active as norepinephrine and is found in the salivary glands of Octopus and Eledone species.
46334	octopamine catabolic process	P	The chemical reactions and pathways resulting in the breakdown of octopamine, 1-(p-hydroxyphenyl)-2-aminoethanol. The D enantiomer is about one-tenth as active as norepinephrine and is found in the salivary glands of Octopus and Eledone species.
46335	ethanolamine biosynthetic process	P	The chemical reactions and pathways resulting in the formation of ethanolamine (2-aminoethanol), an important water-soluble base of phospholipid (phosphatidylethanolamine).
46336	ethanolamine catabolic process	P	The chemical reactions and pathways resulting in the breakdown of ethanolamine (2-aminoethanol), an important water-soluble base of phospholipid (phosphatidylethanolamine).
46337	phosphatidylethanolamine metabolic process	P	The chemical reactions and pathways involving phosphatidylethanolamine, any of a class of glycerophospholipids in which a phosphatidyl group is esterified to the hydroxyl group of ethanolamine. It is a major structural phospholipid in mammalian systems. It tends to be more abundant than phosphatidylcholine in the internal membranes of the cell and is an abundant component of prokaryotic membranes.
46338	phosphatidylethanolamine catabolic process	P	The chemical reactions and pathways resulting in the breakdown of phosphatidylethanolamine, any of a class of glycerophospholipids in which a phosphatidyl group is esterified to the hydroxyl group of ethanolamine.
46339	diacylglycerol metabolic process	P	The chemical reactions and pathways involving diacylglycerol, a glyceride in which any two of the R groups (positions not specified) are acyl groups while the remaining R group can be either H or an alkyl group.
46340	diacylglycerol catabolic process	P	The chemical reactions and pathways resulting in the breakdown of diacylglycerol, a glyceride in which any two of the R groups (positions not specified) are acyl groups while the remaining R group can be either H or an alkyl group.
46341	CDP-diacylglycerol metabolic process	P	The chemical reactions and pathways involving CDP-diacylglycerol, CDP-1,2-diacylglycerol, a substance composed of diacylglycerol in glycosidic linkage with cytidine diphosphate. It is a common intermediate in phospholipid biosynthesis.
46342	CDP-diacylglycerol catabolic process	P	The chemical reactions and pathways resulting in the breakdown of CDP-diacylglycerol, CDP-1,2-diacylglycerol, a substance composed of diacylglycerol in glycosidic linkage with cytidine diphosphate.
46343	streptomycin metabolic process	P	The chemical reactions and pathways involving streptomycin, a commonly used antibiotic in cell culture media. It acts only on prokaryotes and blocks transition from initiation complex to chain elongating ribosome.
46344	ecdysteroid catabolic process	P	The chemical reactions and pathways resulting in the breakdown of ecdysteroids, a group of polyhydroxylated ketosteroids which initiate post-embryonic development.
46345	abscisic acid catabolic process	P	The chemical reactions and pathways resulting in the breakdown of abscisic acid, 5-(1-hydroxy-2,6,6,trimethyl-4-oxocyclohex-2-en-1-y1)-3-methylpenta-2,4-dienoic acid.
46346	mannosamine catabolic process	P	The chemical reactions and pathways resulting in the breakdown of mannosomine, 2-amino-2-deoxymannose; the D-isomer is a constituent of neuraminic acids as well as mucolipids and mucoproteins.
46347	mannosamine biosynthetic process	P	The chemical reactions and pathways resulting in the formation of mannosomine, 2-amino-2-deoxymannose; the D-isomer is a constituent of neuraminic acids as well as mucolipids and mucoproteins.
46348	amino sugar catabolic process	P	The chemical reactions and pathways resulting in the breakdown of any amino sugar, sugars containing an amino group in place of a hydroxyl group.
46349	amino sugar biosynthetic process	P	The chemical reactions and pathways resulting in the formation of any amino sugar, sugars containing an amino group in place of a hydroxyl group.
46350	galactosaminoglycan metabolic process	P	The chemical reactions and pathways involving galactosaminoglycans, any one of a group of polysaccharides that contain amino sugars derived from the galactose.
46351	disaccharide biosynthetic process	P	The chemical reactions and pathways resulting in the formation of disaccharides, sugars composed of two monosaccharide units.
46352	disaccharide catabolic process	P	The chemical reactions and pathways resulting in the breakdown of disaccharides, sugars composed of two monosaccharide units.
46353	aminoglycoside 3-N-acetyltransferase activity	F	Catalysis of the reaction: acetyl-CoA + aminoglycoside = CoA + 3-N-acetylaminoglycoside. This is acetylation of the 3-amino group of the central deoxystreptamine ring.
46354	mannan biosynthetic process	P	The chemical reactions and pathways resulting in the formation of mannan, the main hemicellulose of soft (coniferous) wood, made up of D-mannose, D-glucose and D-galactose.
46355	mannan catabolic process	P	The chemical reactions and pathways resulting in the breakdown of mannan, the main hemicellulose of soft (coniferous) wood, made up of D-mannose, D-glucose and D-galactose.
46356	acetyl-CoA catabolic process	P	The chemical reactions and pathways resulting in the breakdown of acetyl-CoA, a derivative of coenzyme A in which the sulfhydryl group is acetylated.
46357	galactarate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of galactarate, the anion of galactaric acid.
46358	butyrate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of butyrate, the anion of butyric acid.
46359	butyrate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of butyrate, the anion of butyric acid.
46360	2-oxobutyrate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of 2-oxobutyrate, the anion of the organic acid 2-oxobutyric acid, which contains a ketone group on carbon 2.
46361	2-oxobutyrate metabolic process	P	The chemical reactions and pathways involving 2-oxobutyrate, the anion of the organic acid 2-oxobutyric acid, which contains a ketone group on carbon 2.
46362	ribitol biosynthetic process	P	The chemical reactions and pathways resulting in the formation of ribitol, a pentitol derived formally by reduction of the -CHO group of either D- or L-ribose.
46363	ribitol catabolic process	P	The chemical reactions and pathways resulting in the breakdown of ribitol, a pentitol derived formally by reduction of the -CHO group of either D- or L-ribose.
46364	monosaccharide biosynthetic process	P	The chemical reactions and pathways resulting in the formation of monosaccharides, polyhydric alcohols containing either an aldehyde or a keto group and between three to ten or more carbon atoms.
46365	monosaccharide catabolic process	P	The chemical reactions and pathways resulting in the breakdown of monosaccharides, polyhydric alcohols containing either an aldehyde or a keto group and between three to ten or more carbon atoms.
46366	allose biosynthetic process	P	The chemical reactions and pathways resulting in the formation of allose, allo-hexose, an aldohexose similar to glucose, differing only in the configuration of the hydroxyl group of C-3.
46367	allose catabolic process	P	The chemical reactions and pathways resulting in the breakdown of allose, allo-hexose, an aldohexose similar to glucose, differing only in the configuration of the hydroxyl group of C-3.
46368	GDP-L-fucose metabolic process	P	The chemical reactions and pathways involving GDP-L-fucose, a substance composed of L-fucose in glycosidic linkage with guanosine diphosphate.
46369	galactose biosynthetic process	P	The chemical reactions and pathways resulting in the formation of galactose, the aldohexose galacto-hexose.
46370	fructose biosynthetic process	P	The chemical reactions and pathways resulting in the formation of fructose, the ketohexose arabino-2-hexulose.
46371	dTDP-mannose metabolic process	P	The chemical reactions and pathways involving dTDP-mannose, a substance composed of mannose in glycosidic linkage with deoxyribosylthymine diphosphate.
46372	D-arabinose metabolic process	P	The chemical reactions and pathways involving D-arabinose, the D-enantiomer of arabino-pentose. D-arabinose occurs in plant glycosides and is a constituent of arabinonucleosides.
46373	L-arabinose metabolic process	P	The chemical reactions and pathways involving L-arabinose, the D-enantiomer of arabino-pentose. L-arabinose occurs free, e.g. in the heartwood of many conifers, and in the combined state, in both furanose and pyranose forms, as a constituent of various plant hemicelluloses, bacterial polysaccharides etc.
46374	teichoic acid metabolic process	P	The chemical reactions and pathways involving teichoic acid, any polymer occurring in the cell wall, membrane or capsule of Gram-positive bacteria and containing chains of glycerol phosphate or ribitol phosphate residues.
46375	K antigen metabolic process	P	The chemical reactions and pathways involving K antigen, a capsular polysaccharide antigen carried on the surface of bacterial capsules that masks somatic (O) antigens.
46376	GDP-alpha-D-mannosylchitobiosyldiphosphodolichol metabolic process	P	The chemical reactions and pathways involving GDP-alpha-D-mannosylchitobiosyldiphosphodolichol, a substance composed of mannosylchitobiosyldiphosphodolichol in glycosidic linkage with guanosine diphosphate.
46377	colanic acid metabolic process	P	The chemical reactions and pathways involving colanic acid, a capsular bacterial polysaccharide composed of glucose, galactose, fucose and glucuronic acid residues.
46378	enterobacterial common antigen metabolic process	P	The chemical reactions and pathways involving enterobacterial common antigen, an acidic polysaccharide containing N-acetyl-D-glucosamine, N-acetyl-D-mannosaminouronic acid, and 4-acetamido-4,6-dideoxy-D-galactose. A major component of the cell wall outer membrane of Gram-negative bacteria.
46379	extracellular polysaccharide metabolic process	P	The chemical reactions and pathways involving polysaccharides used in extracellular structures.
46380	N-acetylneuraminate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of N-acetylneuraminate, the anion of 5-(acetylamino)-3,5-dideoxy-D-glycero-D-galacto-non-3-ulosonic acid.
46381	CMP-N-acetylneuraminate metabolic process	P	The chemical reactions and pathways involving CMP-N-acetylneuraminate, a substance composed of 5-(acetylamino)-3,5-dideoxy-D-glycero-D-galacto-non-3-ulosonic acid in glycosidic linkage with cytidine monophosphate.
46382	GDP-D-rhamnose metabolic process	P	The chemical reactions and pathways involving GDP-D-rhamnose, a substance composed of rhamnose in glycosidic linkage with guanosine diphosphate.
46383	dTDP-rhamnose metabolic process	P	The chemical reactions and pathways involving dTDP-rhamnose, a substance composed of rhamnose in glycosidic linkage with deoxyribosylthymine diphosphate.
46384	2-deoxyribose 1-phosphate metabolic process	P	The chemical reactions and pathways involving 2-deoxyribose 1-phosphate, the phosphorylated sugar 1-phospho-2-deoxyribose.
46385	deoxyribose phosphate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of deoxyribose phosphate, the phosphorylated sugar 2-deoxy-erythro-pentose.
46386	deoxyribose phosphate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of deoxyribose phosphate, the phosphorylated sugar 2-deoxy-erythro-pentose.
46387	deoxyribose 1,5-bisphosphate metabolic process	P	The chemical reactions and pathways involving deoxyribose 1,5-bisphosphate, the diphosphorylated sugar 1,5-diphospho-2-deoxyribose.
46389	deoxyribose 5-phosphate metabolic process	P	The chemical reactions and pathways involving deoxyribose 5-phosphate, the phosphorylated sugar 5-phospho-2-deoxyribose.
46390	ribose phosphate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of ribose phosphate, any phosphorylated ribose sugar.
46391	5-phosphoribose 1-diphosphate metabolic process	P	The chemical reactions and pathways involving 5-phosphoribose 1-diphosphate, also known as 5-phosphoribosyl-1-pyrophosphate.
46392	galactarate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of galactarate, the anion of galactaric acid.
46394	carboxylic acid biosynthetic process	P	The chemical reactions and pathways resulting in the formation of carboxylic acids, any organic acid containing one or more carboxyl (-COOH) groups.
46395	carboxylic acid catabolic process	P	The chemical reactions and pathways resulting in the breakdown of carboxylic acids, any organic acid containing one or more carboxyl (-COOH) groups.
46396	D-galacturonate metabolic process	P	The chemical reactions and pathways involving D-galacturonate, the D-enantiomer of galacturonate, the anion of galacturonic acid. D-galacturonic acid is a component of plant gums and bacterial cell walls.
46397	galacturonate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of galacturonate, the anion of galacturonic acid.
46398	UDP-glucuronate metabolic process	P	The chemical reactions and pathways involving UDP-glucuronate, a substance composed of glucuronic acid in glycosidic linkage with uridine diphosphate.
46399	glucuronate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of glucuronate, the anion of glucuronic acid.
46400	keto-3-deoxy-D-manno-octulosonic acid metabolic process	P	The chemical reactions and pathways involving keto-3-deoxy-D-manno-octulosonic acid, an acidic sugar present in lipopolysaccharides of the outer membranes of some Gram-negative bacteria.
46401	lipopolysaccharide core region metabolic process	P	The chemical reactions and pathways resulting in the formation of the core region of bacterial lipopolysaccharides, which contains ten saccharide residues. The structure of this core oligosaccharide appears to be similar in closely related bacterial strains.
46402	O antigen metabolic process	P	The chemical reactions and pathways involving the O side chain of a lipopolysaccharide, which determines the antigenic specificity of the organism. It is made up of about 50 repeating units of a branched tetrasaccharide.
46403	polynucleotide 3'-phosphatase activity	F	Catalysis of the reaction: 3'-phosphopolynucleotide + H2O = a polynucleotide + phosphate. Hydrolyzes the free 3'-phosphate resulting from single strand breaks in DNA due to oxidative damage.
46404	ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity	F	Catalysis of the reaction: ATP + 5'-dephospho-DNA = ADP + 5'-phospho-DNA.
46405	glycerol dehydratase activity	F	Catalysis of the reaction: glycerol = 3-hydroxypropanal + H2O.
46406	magnesium protoporphyrin IX methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine(1+) + magnesium protoporphyrin IX = S-adenosyl-L-homocysteine + H(+) + magnesium protoporphyrin IX 13-monomethyl ester.
46408	chlorophyll synthetase activity	F	Catalysis of the reaction: chlorophyllide a + 2 H(+) + phytyl diphosphate = chlorophyll a + diphosphate.
46409	p-coumarate 3-hydroxylase activity	F	Catalysis of the reaction: shikimate or quinate ester of p-coumaric acid + NADPH + H+ + O2 = caffeic acid conjugate (caffeoyl shikimic acid or chlorogenic acid) + H2O + NADP+.
46411	2-keto-3-deoxygluconate transport	P	The directed movement of 2-keto-3-deoxygluconate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore by means of some agent such as a transporter or pore.
46412	phenylmercury acetate metabolic process	P	The chemical reactions and pathways involving phenylmercury acetate, an organomercurial compound composed of a mercury atom attached to a benzene ring and an acetate group.
46413	organomercury catabolic process	P	The chemical reactions and pathways resulting in the breakdown of organomercury compounds, any organic compound containing a mercury atom.
46414	organomercury biosynthetic process	P	The chemical reactions and pathways resulting in the formation of organomercury compounds, any organic compound containing a mercury atom.
46415	urate metabolic process	P	The chemical reactions and pathways involving urate, the anion of uric acid, 2,6,8-trioxypurine, the end product of purine metabolism in certain mammals and the main excretory product in uricotelic animals.
46416	D-amino acid metabolic process	P	The chemical reactions and pathways involving D-amino acids, the D-enantiomers of amino acids.
46417	chorismate metabolic process	P	The chemical reactions and pathways involving chorismate, the anion of (3R-trans)-3-((1-carboxyethenyl)oxy)-4-hydroxy-1,5-cyclohexadiene-1-carboxylic acid.
46418	nopaline metabolic process	P	The chemical reactions and pathways involving nopaline, (N-(I-carboxy-4-guanidinobutyl)glutamic acid), a rare amino-acid derivative.
46419	octopine metabolic process	P	The chemical reactions and pathways involving octopine, (N-(1-carboxy-4-guanidinobutyl)-L-alanine), an amino acid derived opine.
46421	methylisocitrate lyase activity	F	Catalysis of the reaction: (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate = pyruvate + succinate.
46422	violaxanthin de-epoxidase activity	F	Catalysis of the reaction: violaxanthin + 2 ascorbate = zeaxanthin + 2 dehydroascorbate + 2 H2O; and antheraxanthin + ascorbate = zeaxanthin + dehydroascorbate + H2O.
46423	allene-oxide cyclase activity	F	Catalysis of the reaction: (9Z,13S,15Z)-12,13-epoxyoctadeca-9,11,15-trienoate = (15Z)-12-oxophyto-10,15-dienoate.
46424	ferulate 5-hydroxylase activity	F	Catalysis of the reaction: ferulic acid + NADPH + H+ + O2 = 5-hydroxyferulic acid + H2O + NADP+.
46425	regulation of JAK-STAT cascade	P	Any process that modulates the frequency, rate or extent of the JAK-STAT signaling pathway.
46426	negative regulation of JAK-STAT cascade	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the JAK-STAT signaling pathway activity.
46427	positive regulation of JAK-STAT cascade	P	Any process that activates or increases the frequency, rate or extent of the JAK-STAT signaling pathway activity.
46428	1,4-dihydroxy-2-naphthoate octaprenyltransferase activity	F	Catalysis of the reaction: 1,4-dihydroxy-2-naphthoate + polyprenylpyrophosphate = dimethylmenaquinone + diphosphate + CO2.
46429	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase activity	F	Catalysis of the reaction: (E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate + H2O + 2 oxidized ferredoxin = 2-C-methyl-D-erythritol 2,4-cyclodiphosphate + 2 reduced ferredoxin.
46430	non-phosphorylated glucose metabolic process	P	The chemical reactions and pathways involving non-phosphorylated forms of glucose.
46431	(R)-4-hydroxymandelate metabolic process	P	The chemical reactions and pathways involving (R)-4-hydroxymandelate, the anion of a hydroxylated derivative of mandelate (alpha-hydroxybenzeneacetate).
46432	2'-(5''-triphosphoribosyl)-3'-dephospho-CoA metabolic process	P	The chemical reactions and pathways involving 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA, a derivative of coenzyme A.
46433	2-aminoethylphosphonate metabolic process	P	The chemical reactions and pathways involving 2-aminoethylphosphonate, most abundant and ubiquitous of naturally occurring phosphonates. It is typically found as a conjugate of glycans, lipids, and proteins, which in turn perform essential biochemical functions in specialized lower organisms.
46434	organophosphate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of organophosphates, any phosphate-containing organic compound.
46435	3-(3-hydroxy)phenylpropionate metabolic process	P	The chemical reactions and pathways involving 3-(3-hydroxy)phenylpropionate, a hydroxylated derivative of phenylpropionate.
46436	D-alanine metabolic process	P	The chemical reactions and pathways involving D-alanine, the D-enantiomer of the amino acid alanine, i.e. (2R)-2-aminopropanoic acid.
46437	D-amino acid biosynthetic process	P	The chemical reactions and pathways resulting in the formation of D-amino acids, the D-enantiomers of amino acids.
46438	D-cysteine metabolic process	P	The chemical reactions and pathways involving D-cysteine, (S)-2-amino-3-mercaptopropanoic acid, which occurs naturally in firefly luciferin.
46439	L-cysteine metabolic process	P	The chemical reactions and pathways involving L-cysteine, the L-enantiomer of 2-amino-3-mercaptopropanoic acid, i.e. (2R)-2-amino-3-mercaptopropanoic acid.
46440	L-lysine metabolic process	P	The chemical reactions and pathways involving L-lysine, the L-enantiomer of (S)-2,6-diaminohexanoic acid, i.e. (2S)-2,6-diaminohexanoic acid.
46441	D-lysine metabolic process	P	The chemical reactions and pathways involving D-lysine, the D-enantiomer of lysine; i.e. (2R)-2,6-diaminohexanoic acid.
46442	aerobactin metabolic process	P	The chemical reactions and pathways involving aerobactin (C22H36N4O13), a hydroxamate iron transport compound. It is a conjugate of 6-(N-acetyl-N-hydroxylamine)-2-aminohexanoic acid and citric acid.
46443	FAD metabolic process	P	The chemical reactions and pathways involving FAD, the oxidized form of flavin adenine dinucleotide.
46444	FMN metabolic process	P	The chemical reactions and pathways involving FMN, riboflavin 5'-(dihydrogen phosphate), a coenzyme for a number of oxidative enzymes including NADH dehydrogenase.
46445	benzyl isoquinoline alkaloid metabolic process	P	The chemical reactions and pathways involving benzyl isoquinoline alkaloids, compounds with bicyclic N-containing aromatic rings.
46446	purine alkaloid metabolic process	P	The chemical reactions and pathways involving purine alkaloids, compounds derived from purine and composed of an N-containing double ring structure.
46447	terpenoid indole alkaloid metabolic process	P	The chemical reactions and pathways involving terpenoid indole alkaloids, compounds formed from the condensation of tryptamine (derived from tryptophan) and secologanin (derived from geranyl pyrophosphate).
46448	tropane alkaloid metabolic process	P	The chemical reactions and pathways involving tropane alkaloids, compounds containing the 8-methyl-8-azabicyclo(3.2.1)octane ring system.
46449	creatinine metabolic process	P	The chemical reactions and pathways involving creatinine, 2-amino-1,5-dihydro-1-methyl-4H-imidazol-4-one, an end product of creatine metabolism and a normal constituent of urine.
46450	dethiobiotin metabolic process	P	The chemical reactions and pathways involving dethiobiotin, a derivative of biotin formed by replacing the sulfur atom by two hydrogen atoms.
46451	diaminopimelate metabolic process	P	The chemical reactions and pathways involving diaminopimelate, the anion of the dicarboxylic acid 2,6-diaminoheptanedioic acid. It is an intermediate in lysine biosynthesis and as a component (as meso-diaminopimelate) of the peptidoglycan of Gram-negative bacterial cell walls.
46452	dihydrofolate metabolic process	P	The chemical reactions and pathways involving dihydrofolate, the dihydroxylated derivative of folate.
46453	dipyrrin metabolic process	P	The chemical reactions and pathways involving dipyrrins (pyrromethanes), compounds containing two pyrrole rings linked through a methine, -CH=, group.
46454	dimethylsilanediol metabolic process	P	The chemical reactions and pathways involving dimethylsilanediol, the smallest member of the dialkylsilanediols. Dimethylsilanediol is the monomer of polydimethylsiloxane, a compound which can be found in a wide range of industrial and consumer products.
46455	organosilicon catabolic process	P	The chemical reactions and pathways resulting in the breakdown of organosilicons, any organic compound that contains silicon.
46456	icosanoid biosynthetic process	P	The chemical reactions and pathways resulting in the formation of icosanoids, any of a group of C20 polyunsaturated fatty acids.
46457	prostanoid biosynthetic process	P	The chemical reactions and pathways resulting in the formation of prostanoids, any compound based on or derived from the prostanoate structure.
46458	hexadecanal metabolic process	P	The chemical reactions and pathways involving hexadecanal, the C16 straight chain aldehyde.
46459	short-chain fatty acid metabolic process	P	The chemical reactions and pathways involving fatty acids with a chain length of less than C6.
46460	neutral lipid biosynthetic process	P	The chemical reactions and pathways resulting in the formation of neutral lipids, lipids only soluble in solvents of very low polarity.
46461	neutral lipid catabolic process	P	The chemical reactions and pathways resulting in the breakdown of neutral lipids, lipids only soluble in solvents of very low polarity.
46462	monoacylglycerol metabolic process	P	The chemical reactions and pathways involving monoacylglycerol, any ester of glycerol in which any one of its hydroxyl groups has been acylated with a fatty acid, the other being non-esterified.
46463	acylglycerol biosynthetic process	P	The chemical reactions and pathways resulting in the formation of acylglycerol, any mono-, di- or triester of glycerol with (one or more) fatty acids.
46464	acylglycerol catabolic process	P	The chemical reactions and pathways resulting in the breakdown of acylglycerol, any mono-, di- or triester of glycerol with (one or more) fatty acids.
46465	dolichyl diphosphate metabolic process	P	The chemical reactions and pathways involving dolichyl diphosphate, a diphosphorylated dolichol derivative. In eukaryotes, these function as carriers of mono- and oligosaccharide residues in the glycosylation of lipids and proteins within intracellular membranes.
46466	membrane lipid catabolic process	P	The chemical reactions and pathways resulting in the breakdown of membrane lipids, any lipid found in or associated with a biological membrane.
46467	membrane lipid biosynthetic process	P	The chemical reactions and pathways resulting in the formation of membrane lipids, any lipid found in or associated with a biological membrane.
46468	phosphatidyl-N-monomethylethanolamine metabolic process	P	The chemical reactions and pathways involving phosphatidyl-N-monomethylethanolamine (PMME), a derivative of phosphatidylethanolamine with a methylated amine group. Present in trace levels in plants and slightly higher in bacteria.
46469	platelet activating factor metabolic process	P	The chemical reactions and pathways involving platelet activating factor, 1-O-alkyl-2-acetyl-sn-glycerol 3-phosphocholine, where alkyl = hexadecyl or octadecyl. Platelet activating factor is an inflammatory mediator released from a variety of cells in response to various stimuli.
46470	phosphatidylcholine metabolic process	P	The chemical reactions and pathways involving phosphatidylcholines, any of a class of glycerophospholipids in which the phosphatidyl group is esterified to the hydroxyl group of choline. They are important constituents of cell membranes.
46471	phosphatidylglycerol metabolic process	P	The chemical reactions and pathways involving phosphatidylglycerols, any of a class of phospholipids in which the phosphatidyl group is esterified to the hydroxyl group of glycerol. They are important constituents of cell membranes.
46473	phosphatidic acid metabolic process	P	The chemical reactions and pathways involving phosphatidic acid, any derivative of glycerol phosphate in which both the remaining hydroxyl groups of the glycerol moiety are esterified with fatty acids.
46474	glycerophospholipid biosynthetic process	P	The chemical reactions and pathways resulting in the formation of glycerophospholipids, any derivative of glycerophosphate that contains at least one O-acyl, O-alkyl, or O-alkenyl group attached to the glycerol residue.
46475	glycerophospholipid catabolic process	P	The chemical reactions and pathways resulting in the breakdown of glycerophospholipids, any derivative of glycerophosphate that contains at least one O-acyl, O-alkyl, or O-alkenyl group attached to the glycerol residue.
46476	glycosylceramide biosynthetic process	P	The chemical reactions and pathways resulting in the formation of glycosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of a monosaccharide (or derivative) by a ceramide group.
46477	glycosylceramide catabolic process	P	The chemical reactions and pathways resulting in the breakdown of glycosylceramides, any compound formed by the replacement of the glycosidic hydroxyl group of a cyclic form of a monosaccharide (or derivative) by a ceramide group.
46478	lactosylceramide metabolic process	P	The chemical reactions and pathways involving lactosylceramides, Gal-beta-(1->4)-Glc-beta-(1->1') ceramides, any compound formed by the replacement of the glycosidic C1 hydroxyl group of lactose by a ceramide group. They are the precursors of both gangliosides and globosides.
46479	glycosphingolipid catabolic process	P	The chemical reactions and pathways resulting in the breakdown of glycosphingolipid, a compound with residues of sphingoid and at least one monosaccharide.
46480	galactolipid galactosyltransferase activity	F	Catalysis of the reaction: 2 mono-beta-D-galactosyldiacylglycerol = alpha-D-galactosyl-beta-D-galactosyldiacylglycerol + 1,2-diacylglycerol.
46481	digalactosyldiacylglycerol synthase activity	F	Catalysis of the reaction: 1,2-diacyl-3-beta-D-galactosyl-sn-glycerol + UDP-D-galactose = 3-[alpha-D-galactosyl-(1->6)-beta-D-galactosyl]-1,2-diacyl-sn-glycerol + H(+) + UDP.
46482	para-aminobenzoic acid metabolic process	P	The chemical reactions and pathways involving para-aminobenzoic acid, an intermediate in the synthesis of folic acid, a compound which some organisms, e.g. prokaryotes, eukaryotic microbes, and plants, can synthesize de novo. Others, notably mammals, cannot. In yeast, it is present as a factor in the B complex of vitamins.
46483	heterocycle metabolic process	P	The chemical reactions and pathways involving heterocyclic compounds, those with a cyclic molecular structure and at least two different atoms in the ring (or rings).
46484	oxazole or thiazole metabolic process	P	The chemical reactions and pathways involving oxazole or thiazole, five-membered heterocyclic ring structures containing an oxygen and a sulfur, respectively, in the 1-position and a nitrogen in the 3-position.
46485	ether lipid metabolic process	P	The chemical reactions and pathways involving ether lipids, lipids that contain (normally) one lipid alcohol in ether linkage to one of the carbon atoms (normally C-1) of glycerol.
46486	glycerolipid metabolic process	P	The chemical reactions and pathways involving glycerolipids, any lipid with a glycerol backbone. Diacylglycerol and phosphatidate are key lipid intermediates of glycerolipid biosynthesis.
46487	glyoxylate metabolic process	P	The chemical reactions and pathways involving glyoxylate, the anion of glyoxylic acid, HOC-COOH.
46488	phosphatidylinositol metabolic process	P	The chemical reactions and pathways involving phosphatidylinositol, any glycophospholipid in which a sn-glycerol 3-phosphate residue is esterified to the 1-hydroxyl group of 1D-myo-inositol.
46490	isopentenyl diphosphate metabolic process	P	The chemical reactions and pathways involving isopentenyl diphosphate, an isomer of dimethylallyl diphosphate and the key precursor of all isoprenoids.
46491	L-methylmalonyl-CoA metabolic process	P	The chemical reactions and pathways involving L-methylmalonyl-CoA, the L-enantiomer of 2-carboxypropanoyl-CoA. S-methylmalonyl-CoA is an intermediate in the beta oxidation of odd-numbered fatty acids in animals.
46492	heme b metabolic process	P	The chemical reactions and pathways involving heme b, a Fe(II) porphyrin complex readily isolated from the hemoglobin of beef blood, but also found in other proteins including other hemoglobins, myoglobins, cytochromes P-450, catalases, peroxidases as well as b type cytochromes.
46493	lipid A metabolic process	P	The chemical reactions and pathways involving lipid A, the glycolipid group of bacterial lipopolysaccharides, consisting of six fatty acyl chains linked to two glucosamine residues.
46494	rhizobactin 1021 metabolic process	P	The chemical reactions and pathways involving rhizobactin 1021, (E)-4-((3-(acetylhydroxyamino)propyl)-amino)-2-hydroxy-(2-(2-(3-(hydroxy(1-oxo-2-decenyl)amino)propyl)amino)-2-oxoethyl)-4-oxobutanoic acid, a siderophore produced by Sinorhizobium meliloti.
46495	nicotinamide riboside metabolic process	P	The chemical reactions and pathways involving nicotinamide riboside, the product of the formation of a glycosidic bond between ribose and nicotinamide.
46496	nicotinamide nucleotide metabolic process	P	The chemical reactions and pathways involving nicotinamide nucleotides, any nucleotide that contains combined nicotinamide.
46497	nicotinate nucleotide metabolic process	P	The chemical reactions and pathways involving nicotinamide nucleotides, any nucleotide that contains combined nicotinate (pyridine 3-carboxylic acid, or niacin).
46498	S-adenosylhomocysteine metabolic process	P	The chemical reactions and pathways involving S-adenosylhomocysteine; the L-enantiomer is formed from S-adenosylmethionine and is a strong inhibitor of S-adenosylmethionine-mediated methylation reactions. It can be cleaved to form adenosine and homocysteine.
46499	S-adenosylmethioninamine metabolic process	P	The chemical reactions and pathways involving S-adenosylmethioninamine, (5-deoxy-5-adenosyl)(3-aminopropyl) methylsulfonium salt.
46500	S-adenosylmethionine metabolic process	P	The chemical reactions and pathways involving S-adenosylmethionine, S-(5'-adenosyl)-L-methionine, an important intermediate in one-carbon metabolism.
46501	protoporphyrinogen IX metabolic process	P	The chemical reactions and pathways involving protoporphyrinogen IX, the specific substrate for the enzyme ferrochelatase, which catalyzes the insertion of iron to form protoheme. It is probably also the substrate for chlorophyll formation.
46502	uroporphyrinogen III metabolic process	P	The chemical reactions and pathways involving uroporphyrinogen III, a precursor for synthesis of vitamin B12, chlorophyll, and heme in organisms that produce these compounds.
46503	glycerolipid catabolic process	P	The chemical reactions and pathways resulting in the breakdown of glycerolipids, any lipid with a glycerol backbone.
46504	glycerol ether biosynthetic process	P	The chemical reactions and pathways resulting in the formation of glycerol ethers, any anhydride formed between two organic hydroxy compounds, one of which is glycerol.
46505	sulfolipid metabolic process	P	The chemical reactions and pathways involving sulfolipids, any compound containing a sulfonic acid residue joined by a carbon-sulfur bond to a lipid.
46506	sulfolipid biosynthetic process	P	The chemical reactions and pathways resulting in the formation of sulfolipid, a compound containing a sulfonic acid residue joined by a carbon-sulfur bond to a lipid.
46507	UDPsulfoquinovose synthase activity	F	Catalysis of the reaction: sulfite + UDP-D-glucose = H(2)O + UDP-6-sulfoquinovose.
46508	hydrolase activity, acting on carbon-sulfur bonds	F	Catalysis of the hydrolysis of any carbon-sulfur bond, C-S.
46509	1,2-diacylglycerol 3-beta-galactosyltransferase activity	F	Catalysis of the reaction: 1,2-diacyl-sn-glycerol + UDP-D-galactose = 1,2-diacyl-3-beta-D-galactosyl-sn-glycerol + H(+) + UDP.
46510	UDP-sulfoquinovose:DAG sulfoquinovosyltransferase activity	F	Catalysis of the reaction: UDP-sulfoquinovose + 1,2-diacylglycerol = sulfoquinovosyldiacylglycerol + UDP.
46511	sphinganine biosynthetic process	P	The chemical reactions and pathways resulting in the formation of sphinganine, D-erythro-2-amino-1,3-octadecanediol.
46512	sphingosine biosynthetic process	P	The chemical reactions and pathways resulting in the formation of sphingosine (sphing-4-enine), trans-D-erytho-2-amino-octadec-4-ene-1,3-diol, a long chain amino diol sphingoid base that occurs in most sphingolipids in animal tissues.
46513	ceramide biosynthetic process	P	The chemical reactions and pathways resulting in the formation of ceramides, any N-acylated sphingoid.
46514	ceramide catabolic process	P	The chemical reactions and pathways resulting in the breakdown of ceramides, any N-acetylated sphingoid.
46516	hypusine metabolic process	P	The chemical reactions and pathways involving hypusine, N6-(4-amino-2-hydroxybutyl)-L-lysine.
46517	octamethylcyclotetrasiloxane catabolic process	P	The chemical reactions and pathways resulting in the breakdown of octamethylcyclotetrasiloxane, a cyclic silicone-oxygen ring compound with two methyl groups attached to each silicone atom.
46518	octamethylcyclotetrasiloxane metabolic process	P	The chemical reactions and pathways involving octamethylcyclotetrasiloxane, a cyclic silicone-oxygen ring compound with two methyl groups attached to each silicone atom.
46519	sphingoid metabolic process	P	The chemical reactions and pathways involving sphingoids, any of a class of compounds comprising sphinganine and its homologues and stereoisomers, and derivatives of these compounds.
46520	sphingoid biosynthetic process	P	The chemical reactions and pathways resulting in the formation of sphingoids, any of a class of compounds comprising sphinganine and its homologues and stereoisomers, and derivatives of these compounds.
46521	sphingoid catabolic process	P	The chemical reactions and pathways resulting in the breakdown of sphingoids, any of a class of compounds comprising sphinganine and its homologues and stereoisomers, and derivatives of these compounds.
46522	S-methyl-5-thioribose kinase activity	F	Catalysis of the reaction: S-methyl-5-thio-D-ribose + ATP = S-methyl-5-thio-alpha-D-ribose 1-phosphate + ADP + 2 H(+).
46523	S-methyl-5-thioribose-1-phosphate isomerase activity	F	Catalysis of the reaction: S-methyl-5-thio-alpha-D-ribose 1-phosphate = S-methyl-5-thio-D-ribulose 1-phosphate.
46524	sucrose-phosphate synthase activity	F	Catalysis of the reaction: UDP-glucose + D-fructose 6-phosphate = UDP + sucrose 6-phosphate.
46525	xylosylprotein 4-beta-galactosyltransferase activity	F	Catalysis of the reaction: UDP-galactose + O-beta-D-xylosylprotein = UDP + 4-beta-D-galactosyl-O-beta-D-xylosylprotein.
46526	D-xylulose reductase activity	F	Catalysis of the reaction: NAD(+) + xylitol = D-xylulose + H(+) + NADH.
46527	glucosyltransferase activity	F	Catalysis of the transfer of a glucosyl group to an acceptor molecule, typically another carbohydrate or a lipid.
46528	imaginal disc fusion	P	The process following disc eversion whereby imaginal discs fuse with adjacent disc derivatives to form a continuous adult epidermis.
46529	imaginal disc fusion, thorax closure	P	The joining of the parts of the wing imaginal discs, giving rise to the adult thorax.
46530	photoreceptor cell differentiation	P	The specialization of organization of a photoreceptor, a cell that responds to incident electromagnetic radiation, particularly visible light. An example of this process is found in Drosophila melanogaster.
46532	regulation of photoreceptor cell differentiation	P	Any process that modulates the frequency, rate or extent of photoreceptor cell differentiation. An example of this process is found in Drosophila melanogaster.
46533	negative regulation of photoreceptor cell differentiation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of photoreceptor cell differentiation. An example of this process is found in Drosophila melanogaster.
46534	positive regulation of photoreceptor cell differentiation	P	Any process that activates or increases the frequency, rate or extent of photoreceptor cell differentiation. An example of this process is found in Drosophila melanogaster.
46535	detection of chemical stimulus involved in sensory perception of umami taste	P	The series of events required for a umami taste stimulus to be received and converted to a molecular signal. Umami taste is the savory taste of meats and other foods that are rich in glutamates.
46536	dosage compensation complex	C	A protein or protein-RNA complex that localizes to one or more of the sex chromosome(s), where it acts to normalize transcription between different sexes.
46537	2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity	F	Catalysis of the reaction: 2-phospho-D-glycerate = 3-phospho-D glycerate; this reaction does not require the cofactor 2,3-bisphosphoglycerate.
46538	2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity	F	Catalysis of the reaction: 2-phospho-D-glycerate = 3-phospho-D-glycerate; this reaction requires the cofactor 2,3-bisphosphoglycerate.
46539	histamine N-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine(1+) + histamine = N(tau)-methylhistamine + S-adenosyl-L-homocysteine + H(+).
46540	U4/U6 x U5 tri-snRNP complex	C	A ribonucleoprotein complex formed by the association of the U4/U6 and U5 small nuclear ribonucleoproteins.
46541	saliva secretion	P	The regulated release of saliva from the salivary glands. In man, the saliva is a turbid and slightly viscous fluid, generally of an alkaline reaction, and is secreted by the parotid, submaxillary, and sublingual glands. In the mouth the saliva is mixed with the secretion from the buccal glands. In man and many animals, saliva is an important digestive fluid on account of the presence of the peculiar enzyme, ptyalin.
46543	development of secondary female sexual characteristics	P	The process whose specific outcome is the progression of the secondary female sexual characteristics over time, from their formation to the mature structures. In female humans, these include growth of axillary and pubic hair, breast development and menstrual periods. Their development occurs in response to sex hormone secretion.
46544	development of secondary male sexual characteristics	P	The process whose specific outcome is the progression of the secondary male sexual characteristics over time, from their formation to the mature structures. In male humans, these include growth of axillary, chest, and pubic hair, voice changes, and testicular/penile enlargement. Development occurs in response to sex hormone secretion.
46545	development of primary female sexual characteristics	P	The process whose specific outcome is the progression of the primary female sexual characteristics over time, from their formation to the mature structure. The primary female sexual characteristics are the ovaries, and they develop in response to sex hormone secretion.
46546	development of primary male sexual characteristics	P	The process whose specific outcome is the progression of the primary male sexual characteristics over time, from their formation to the mature structures. The primary male sexual characteristics are the testes, and they develop in response to sex hormone secretion.
46547	trans-aconitate 3-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine(1+) + trans-aconitate = (E)-2-(methoxycarbonylmethyl)but-2-enedioate + S-adenosyl-L-homocysteine.
46548	retinal rod cell development	P	Development of a rod cell, one of the sensory cells in the eye that reacts to the presence of light. Rod cells contain the photopigment rhodopsin or porphyropsin and are responsible for vision in dim light.
46549	retinal cone cell development	P	Development of a cone cell, one of the sensory cells in the eye that reacts to the presence of light. Cone cells contain the photopigment iodopsin or cyanopsin and are responsible for photopic (daylight) vision.
46550	(3-aminopropyl)(L-aspartyl-1-amino)phosphoryl-5'-adenosine biosynthetic process from asparagine	P	The modification of asparagine to (3-aminopropyl)(L-aspartyl-1-amino)phosphoryl-5'-adenosine as found in microcin C7 produced from the mccA gene in E. coli plasmid pMccC7.
46551	retinal cone cell fate commitment	P	The process in which the developmental fate of a cell becomes restricted such that it will develop into a retinal cone cell. A retinal cone cell is one of the two photoreceptor subtypes in a camera-type eye.
46552	photoreceptor cell fate commitment	P	The process in which the developmental fate of a cell becomes restricted such that it will develop into a photoreceptor cell. A photoreceptor cell is a cell that responds to incident electromagnetic radiation. Different classes of photoreceptor have different spectral sensitivities and express different photosensitive pigments.
46553	D-malate dehydrogenase (decarboxylating) activity	F	Catalysis of the reaction: (R)-malate + NAD(+) = CO(2) + NADH + pyruvate.
46554	malate dehydrogenase (NADP+) activity	F	Catalysis of the reaction: (S)-malate + NADP+ = oxaloacetate + NADPH + H+.
46555	acetylxylan esterase activity	F	Catalysis of the deacetylation of xylans and xylo-oligosaccharides.
46556	alpha-L-arabinofuranosidase activity	F	Catalysis of the hydrolysis of terminal non-reducing alpha-L-arabinofuranoside residues in alpha-L-arabinosides.
46557	glucan endo-1,6-beta-glucosidase activity	F	Catalysis of the random hydrolysis of (1->6) linkages in (1->6)-beta-D-glucans.
46558	arabinan endo-1,5-alpha-L-arabinosidase activity	F	Catalysis of the endohydrolysis of (1->5)-alpha-arabinofuranosidic linkages in (1->5) arabinans.
46559	alpha-glucuronidase activity	F	Catalysis of the reaction: an alpha-D-glucuronoside + H2O = an alcohol + D-glucuronate.
46562	glucose oxidase activity	F	Catalysis of the reaction: beta-D-glucose + O2 = D-glucono-1,5-lactone + H2O2.
46563	methanol oxidase activity	F	Catalysis of the reaction: O2 + methanol = H2O2 + formaldehyde.
46564	oxalate decarboxylase activity	F	Catalysis of the reaction: H(+) + oxalate = CO(2) + formate.
46565	3-dehydroshikimate dehydratase activity	F	Catalysis of the reaction: 3-dehydroshikimate = 3,4-dihydroxybenzoate + H2O. 3,4-dihydroxybenzoate is also known as protocatechuate.
46566	DOPA dioxygenase activity	F	Catalysis of the 4,5-ring opening reaction: 3,4-dihydroxyphenylalanine + O2 = 4,5-seco-DOPA. 4,5-seco-DOPA spontaneously recyclizes to form betalamic acid.
46567	aphidicolan-16 beta-ol synthase activity	F	Catalysis of the reaction: 9-alpha-copalyl diphosphate + H2O = aphidicolan-16-beta-ol + diphosphate.
46568	3-methylbutanol:NAD(P) oxidoreductase activity	F	Catalysis of the reaction: 3-methylbutanol + NAD(P)+ = 3-methylbutanal + NAD(P)H + H+. 3-methylbutanal is also known as isovaleraldehyde.
46569	glyoxal oxidase activity	F	Catalysis of the reaction: glyoxal + O2 + H2O = glyoxalate + H2O2.
46570	methylthioribulose 1-phosphate dehydratase activity	F	Catalysis of the reaction: S-methyl-5-thio-D-ribulose 1-phosphate = 5-(methylthio)-2,3-dioxopentyl phosphate + H(2)O.
46571	aspartate-2-keto-4-methylthiobutyrate transaminase activity	F	Catalysis of the reaction: 2-keto-4-methylthiobutyrate + aspartate = methionine + oxaloacetate.
46572	versicolorin B synthase activity	F	Catalysis of the reaction: versiconal = versicolorin B + H2O.
46573	lactonohydrolase activity	F	Catalysis of the hydrolysis of lactone rings (intramolecular cyclic esters) to produce a hydroxyl group and a carboxyl group.
46574	glycuronidase activity	F	Catalysis of the hydrolysis of glucuronosides, yielding free glucuronic acid.
46575	rhamnogalacturonan acetylesterase activity	F	Catalysis of the removal of acetylesters (as acetate) from galacturonic acid residues in the backbone of rhamnogalacturonan.
46576	rhamnogalacturonan alpha-L-rhamnopyranosyl-(1->4)-alpha-D-galactopyranosyluronide lyase activity	F	Catalysis of the cleavage of rhamnogalacturonan, generating oligosaccharides of the form alpha-D-us-galacturonic acid-(1,2)-alpha-L-rhamnose-(1,4)-alpha-D-galacturonate-(1,2)-L-rhamnose-(1,2)-alpha-L-rhamnose-p-(1,4)-alpha-D-galacturonic acid, terminating at the non-reducing end with a hex-4-enopyranosyluronic acid residue.
46577	long-chain-alcohol oxidase activity	F	Catalysis of the reaction: 2 long-chain alcohol + O2 = 2 long-chain aldehyde + 2 H2O.
46578	regulation of Ras protein signal transduction	P	Any process that modulates the frequency, rate or extent of Ras protein signal transduction.
46579	positive regulation of Ras protein signal transduction	P	Any process that activates or increases the frequency, rate or extent of Ras protein signal transduction.
46580	negative regulation of Ras protein signal transduction	P	Any process that stops, prevents, or reduces the frequency, rate or extent of Ras protein signal transduction.
46581	intercellular canaliculus	C	An extremely narrow tubular channel located between adjacent cells. An instance of this is the secretory canaliculi occurring between adjacent parietal cells in the gastric mucosa of vertebrates.
46583	cation efflux transmembrane transporter activity	F	Catalysis of the transfer of a cation or cations from the inside of the cell to the outside of the cell across a membrane.
46584	enniatin metabolic process	P	The chemical reactions and pathways involving enniatins, any of various cyclodepsipeptide antibiotics from Fusarium species that function as ionophores.
46585	enniatin biosynthetic process	P	The chemical reactions and pathways resulting in the formation of enniatins, any of various cyclodepsipeptide antibiotics from Fusarium species that function as ionophores.
46586	regulation of calcium-dependent cell-cell adhesion	P	Any process that modulates the frequency, rate or extent of the attachment of one cell to another cell via adhesion molecules that require the presence of calcium for the interaction.
46587	positive regulation of calcium-dependent cell-cell adhesion	P	Any process that activates or increases the frequency, rate or extent of calcium-dependent cell-cell adhesion.
46588	negative regulation of calcium-dependent cell-cell adhesion	P	Any process that stops, prevents, or reduces the frequency, rate or extent of calcium-dependent cell-cell adhesion.
46589	ribonuclease T1 activity	F	Catalysis of the endonucleolytic cleavage to nucleoside 3'-phosphates and 3'-phosphooligonucleotides ending in Gp with 2',3'-cyclic phosphate intermediates.
46592	polyamine oxidase activity	F	Catalysis of the oxidative degradation or interconversion of polyamines.
46593	mandelonitrile lyase activity	F	Catalysis of the reaction: mandelonitrile = cyanide + benzaldehyde.
46594	maintenance of pole plasm mRNA location	P	The process of maintaining mRNA in a specific location in the oocyte pole plasm. An example of this process is found in Drosophila melanogaster.
46595	establishment of pole plasm mRNA localization	P	Any process that results in the directed movement of mRNA to the oocyte pole plasm.
46596	regulation of viral entry into host cell	P	Any process that modulates the frequency, rate or extent of the viral entry into the host cell.
46597	negative regulation of viral entry into host cell	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the entry of viral entry into a host cell.
46598	positive regulation of viral entry into host cell	P	Any process that activates or increases the frequency, rate or extent of the introduction of viral entry into the host cell.
46599	regulation of centriole replication	P	Any process that modulates the frequency, rate or extent of the formation of a daughter centriole of an existing centriole.
46600	negative regulation of centriole replication	P	Any process that stops, prevents, or reduces the frequency, rate or extent of centriole replication.
46601	positive regulation of centriole replication	P	Any process that activates or increases the frequency, rate or extent of centriole replication.
46602	regulation of mitotic centrosome separation	P	Any process that modulates the frequency, rate or extent of the separation of duplicated centrosome components at the beginning of mitosis.
46603	negative regulation of mitotic centrosome separation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of centrosome separation.
46604	positive regulation of mitotic centrosome separation	P	Any process that activates or increases the frequency, rate or extent of centrosome separation.
46605	regulation of centrosome cycle	P	Any process that modulates the frequency, rate or extent of the centrosome cycle, the processes of centrosome duplication and separation.
46606	negative regulation of centrosome cycle	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the centrosome cycle.
46607	positive regulation of centrosome cycle	P	Any process that activates or increases the frequency, rate or extent of the centrosome cycle.
46608	carotenoid isomerase activity	F	Catalysis of the isomerization of poly-cis-carotenoids to all-trans-carotenoids.
46609	voltage-gated sulfate antiporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: sulfate(out) + solute(in) = solute(in) + sulfate(out), by a channel in a cell membrane whose opening is governed by the membrane potential.
46610	lysosomal proton-transporting V-type ATPase, V0 domain	C	The V0 domain of a proton-transporting V-type ATPase found in the lysosomal membrane.
46611	lysosomal proton-transporting V-type ATPase complex	C	A proton-transporting two-sector ATPase complex found in the lysosomal membrane, where it acts as a proton pump to mediate acidification of the lysosomal lumen.
46612	lysosomal proton-transporting V-type ATPase, V1 domain	C	The V1 domain of a proton-transporting V-type ATPase found in the lysosomal membrane.
46618	drug export	P	The directed movement of a drug, a substance used in the diagnosis, treatment or prevention of a disease, out of a cell or organelle.
46619	optic placode formation involved in camera-type eye formation	P	Establishment and formation of the optic placode, paired ectodermal placodes that become invaginated to form the embryonic lens vesicles.
46620	regulation of organ growth	P	Any process that modulates the frequency, rate or extent of growth of an organ of an organism.
46621	negative regulation of organ growth	P	Any process that stops, prevents, or reduces the frequency, rate or extent of growth of an organ of an organism.
46622	positive regulation of organ growth	P	Any process that activates or increases the frequency, rate or extent of growth of an organ of an organism.
46623	sphingolipid-translocating ATPase activity	F	Catalysis of the movement of sphingolipids from one membrane face to the other ('flippase' activity), driven by the hydrolysis of ATP.
46624	sphingolipid transporter activity	F	Enables the directed movement of sphingolipids into, out of or within a cell, or between cells. Sphingolipids are a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid).
46625	sphingolipid binding	F	Interacting selectively and non-covalently with sphingolipids, a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid).
46626	regulation of insulin receptor signaling pathway	P	Any process that modulates the frequency, rate or extent of insulin receptor signaling.
46627	negative regulation of insulin receptor signaling pathway	P	Any process that stops, prevents, or reduces the frequency, rate or extent of insulin receptor signaling.
46628	positive regulation of insulin receptor signaling pathway	P	Any process that increases the frequency, rate or extent of insulin receptor signaling.
46629	gamma-delta T cell activation	P	The change in morphology and behavior of a gamma-delta T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.
46630	gamma-delta T cell proliferation	P	The expansion of a gamma-delta T cell population by cell division.
46631	alpha-beta T cell activation	P	The change in morphology and behavior of an alpha-beta T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.
46632	alpha-beta T cell differentiation	P	The process in which a precursor cell type acquires the specialized features of an alpha-beta T cell. An alpha-beta T cell is a T cell that expresses an alpha-beta T cell receptor complex.
46633	alpha-beta T cell proliferation	P	The expansion of an alpha-beta T cell population by cell division.
46634	regulation of alpha-beta T cell activation	P	Any process that modulates the frequency, rate or extent of alpha-beta T cell activation.
46635	positive regulation of alpha-beta T cell activation	P	Any process that activates or increases the frequency, rate or extent of alpha-beta T cell activation.
46636	negative regulation of alpha-beta T cell activation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of alpha-beta T cell activation.
46637	regulation of alpha-beta T cell differentiation	P	Any process that modulates the frequency, rate or extent of alpha-beta T cell differentiation.
46638	positive regulation of alpha-beta T cell differentiation	P	Any process that activates or increases the frequency, rate or extent of alpha-beta T cell differentiation.
46639	negative regulation of alpha-beta T cell differentiation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of alpha-beta T cell differentiation.
46640	regulation of alpha-beta T cell proliferation	P	Any process that modulates the frequency, rate or extent of alpha-beta T cell proliferation.
46641	positive regulation of alpha-beta T cell proliferation	P	Any process that activates or increases the frequency, rate or extent of alpha-beta T cell proliferation.
46642	negative regulation of alpha-beta T cell proliferation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of alpha-beta T cell proliferation.
46643	regulation of gamma-delta T cell activation	P	Any process that modulates the frequency, rate or extent of gamma-delta T cell activation.
46644	negative regulation of gamma-delta T cell activation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of gamma-delta T cell activation.
46645	positive regulation of gamma-delta T cell activation	P	Any process that activates or increases the frequency, rate or extent of gamma-delta T cell activation.
46646	regulation of gamma-delta T cell proliferation	P	Any process that modulates the frequency, rate or extent of gamma-delta T cell proliferation.
46647	negative regulation of gamma-delta T cell proliferation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of gamma-delta T cell proliferation.
46648	positive regulation of gamma-delta T cell proliferation	P	Any process that activates or increases the frequency, rate or extent of gamma-delta T cell proliferation.
46649	lymphocyte activation	P	A change in morphology and behavior of a lymphocyte resulting from exposure to a specific antigen, mitogen, cytokine, chemokine, cellular ligand, or soluble factor.
46651	lymphocyte proliferation	P	The expansion of a lymphocyte population by cell division.
46653	tetrahydrofolate metabolic process	P	The chemical reactions and pathways involving tetrahydrofolate, 5,6,7,8-tetrahydrofolic acid, a folate derivative bearing additional hydrogens on the pterin group.
46654	tetrahydrofolate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of tetrahydrofolate, 5,6,7,8-tetrahydrofolic acid, a folate derivative bearing additional hydrogens on the pterin group.
46655	folic acid metabolic process	P	The chemical reactions and pathways involving folic acid, pteroylglutamic acid. Folic acid is widely distributed as a member of the vitamin B complex and is essential for the synthesis of purine and pyrimidines.
46656	folic acid biosynthetic process	P	The chemical reactions and pathways resulting in the formation of folic acid, pteroylglutamic acid.
46657	folic acid catabolic process	P	The chemical reactions and pathways resulting in the breakdown of folic acid, pteroylglutamic acid.
46658	anchored component of plasma membrane	C	The component of the plasma membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group, that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping.
46659	digestive hormone activity	F	The action characteristic of a hormone that takes part in the digestion process.
46660	female sex differentiation	P	The establishment of the sex of a female organism by physical differentiation.
46661	male sex differentiation	P	The establishment of the sex of a male organism by physical differentiation.
46662	regulation of oviposition	P	Any process that modulates the frequency, rate or extent of the deposition of eggs, either fertilized or not, upon a surface or into a medium.
46663	dorsal closure, leading edge cell differentiation	P	The process in which a relatively unspecialized cell acquires specialized features of a leading edge cell, the dorsal-most cells of the epidermis that migrates during dorsal closure.
46664	dorsal closure, amnioserosa morphology change	P	The changes that occur during dorsal closure of the shape and structure of the amnioserosa, an epithelium that occupies the dorsal side of the embryo.
46665	amnioserosa maintenance	P	Maintenance of the amnioserosa, an epithelium that occupies a hole in the embryonic dorsal epidermis.
46666	retinal cell programmed cell death	P	Programmed cell death that occurs in the developing retina.
46667	compound eye retinal cell programmed cell death	P	Programmed cell death that occurs in the retina to remove excess cells between ommatidia, thus resulting in a hexagonal lattice, precise with respect to cell number and position surrounding each ommatidium.
46668	regulation of retinal cell programmed cell death	P	Any process that modulates the frequency, rate or extent of programmed cell death that occurs in the retina.
46669	regulation of compound eye retinal cell programmed cell death	P	Any process that modulates the frequency, rate or extent of programmed cell death that occurs in the compound eye retina.
46670	positive regulation of retinal cell programmed cell death	P	Any process that activates or increases the frequency, rate or extent of programmed cell death that occurs in the retina.
46671	negative regulation of retinal cell programmed cell death	P	Any process that stops, prevents, or reduces the frequency, rate or extent of programmed cell death that occurs in the retina.
46672	positive regulation of compound eye retinal cell programmed cell death	P	Any process that activates or increases the frequency, rate or extent of programmed cell death that occurs in the compound eye retina.
46673	negative regulation of compound eye retinal cell programmed cell death	P	Any process that stops, prevents, or reduces the frequency, rate or extent of programmed cell death that occurs in the compound eye retina.
46676	negative regulation of insulin secretion	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of insulin.
46677	response to antibiotic	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antibiotic stimulus. An antibiotic is a chemical substance produced by a microorganism which has the capacity to inhibit the growth of or to kill other microorganisms.
46678	response to bacteriocin	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bacteriocin stimulus. A bacteriocin is a protein substance released by certain bacteria that kills but does not lyse closely related strains of bacteria. Specific bacteriocins attach to specific receptors on cell walls and induce specific metabolic block, e.g. cessation of nucleic acid or protein synthesis of oxidative phosphorylation.
46679	response to streptomycin	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a streptomycin stimulus. Streptomycin is a commonly used antibiotic in cell culture media which acts only on prokaryotes and blocks transition from initiation complex to chain elongating ribosome.
46680	response to DDT	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a DDT stimulus. DDT, dichlorodiphenyltrichloroethane, is a chlorinated hydrocarbon pesticide moderately toxic to humans and other animals.
46681	response to carbamate	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbamate stimulus. Carbamates are a group of insecticides and parasiticides that act by inhibiting cholinesterase.
46682	response to cyclodiene	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cyclodiene stimulus. A cyclodiene is any organic insecticide (as dieldrin or chlordane) with a chlorinated methylene group forming a bridge across a 6-membered carbon ring.
46683	response to organophosphorus	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organophosphorus stimulus. Organophosphorus is a compound containing phosphorus bound to an organic molecule; several organophosphorus compounds are used as insecticides, and they are highly toxic cholinesterase inhibitors.
46684	response to pyrethroid	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pyrethroid stimulus. Pyrethroids are a group of growth regulators, analogous to insect juvenile hormones, that interfere with the development of insect larvae and are used in the control of insects that are harmful in the adult stage.
46685	response to arsenic-containing substance	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an arsenic stimulus from compounds containing arsenic, including arsenates, arsenites, and arsenides.
46686	response to cadmium ion	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cadmium (Cd) ion stimulus.
46687	response to chromate	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chromate stimulus.
46688	response to copper ion	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a copper ion stimulus.
46689	response to mercury ion	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mercury ion stimulus.
46690	response to tellurium ion	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tellurium ion stimulus.
46691	intracellular canaliculus	C	An apical plasma membrane part that forms a narrow enfolded luminal membrane channel, lined with numerous microvilli, that appears to extend into the cytoplasm of the cell. A specialized network of intracellular canaliculi is a characteristic feature of parietal cells of the gastric mucosa in vertebrates.
46692	sperm competition	P	Any process that contributes to the success of sperm fertilization in multiply-mated females.
46693	sperm storage	P	The retention of sperm by a female following mating.
46694	sperm incapacitation	P	The process in which the use of stored sperm from the first-mating male is inhibited by the seminal fluid of subsequently mating males.
46695	SLIK (SAGA-like) complex	C	A SAGA-type histone acetyltransferase complex that contains Rtg2 and a smaller form of Spt7 than the fungal SAGA complex, and lacks Spt8. The complex is involved in the yeast retrograde response pathway, which is important for gene expression changes during mitochondrial dysfunction.
46696	lipopolysaccharide receptor complex	C	A multiprotein complex that consists of at least three proteins, CD14, TLR4, and MD-2, each of which is glycosylated and which functions as a lipopolysaccharide (LPS) receptor that primes the innate immune response against bacterial pathogens.
46697	decidualization	P	The cellular and vascular changes occurring in the endometrium of the pregnant uterus just after the onset of blastocyst implantation. This process involves the proliferation and differentiation of the fibroblast-like endometrial stromal cells into large, polyploid decidual cells that eventually form the maternal component of the placenta.
46700	heterocycle catabolic process	P	The chemical reactions and pathways resulting in the breakdown of heterocyclic compounds, those with a cyclic molecular structure and at least two different atoms in the ring (or rings).
46701	insecticide catabolic process	P	The chemical reactions and pathways resulting in the breakdown of insecticides, chemicals used to kill insects.
46702	galactoside 6-L-fucosyltransferase activity	F	Catalysis of the transfer of an L-fucosyl group from GDP-beta-L-fucose to a galactoside acceptor molecule, usually an N-glycan, to form an alpha(1,6)-fucosylated galactoside.
46703	natural killer cell lectin-like receptor binding	F	Interacting selectively and non-covalently with a lectin-like natural killer cell receptor.
46704	CDP metabolic process	P	The chemical reactions and pathways involving CDP, cytidine (5'-)diphosphate.
46705	CDP biosynthetic process	P	The chemical reactions and pathways resulting in the formation of CDP, cytidine (5'-)diphosphate.
46706	CDP catabolic process	P	The chemical reactions and pathways resulting in the breakdown of CDP, cytidine (5'-)diphosphate.
46707	IDP metabolic process	P	The chemical reactions and pathways involving IDP, inosine 5'-diphosphate.
46708	IDP biosynthetic process	P	The chemical reactions and pathways resulting in the formation of IDP, inosine 5'-diphosphate.
46709	IDP catabolic process	P	The chemical reactions and pathways resulting in the breakdown of IDP, inosine 5'-diphosphate.
46710	GDP metabolic process	P	The chemical reactions and pathways involving GDP, guanosine 5'-diphosphate.
46711	GDP biosynthetic process	P	The chemical reactions and pathways resulting in the formation of GDP, guanosine 5'-diphosphate.
46712	GDP catabolic process	P	The chemical reactions and pathways resulting in the breakdown of GDP, guanosine 5'-diphosphate.
46713	borate transport	P	The directed movement of borate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Borate is the anion (BO3)3-; boron is a group 13 element, with properties which are borderline between metals and non-metals.
46714	borate binding	F	Interacting selectively and non-covalently with borate, the anion (BO3)3-.
46715	borate transmembrane transporter activity	F	Enables the transport of borate across a membrane against the concentration gradient.
46716	muscle cell cellular homeostasis	P	The cellular homeostatic process that preserves a muscle cell in a stable functional or structural state.
46717	acid secretion	P	The controlled release of acid by a cell or a tissue.
46718	viral entry into host cell	P	The process that occurs after viral attachment by which a virus, or viral nucleic acid, breaches the plasma membrane or cell envelope and enters the host cell. The process ends when the viral nucleic acid is released into the host cell cytoplasm.
46719	regulation by virus of viral protein levels in host cell	P	Any virus-mediated process that modulates the levels of viral proteins in a cell.
46720	citric acid secretion	P	The controlled release of citric acid, 2-hydroxy-1,2,3-propanetricarboxylic acid, by a cell or a tissue.
46721	formic acid secretion	P	The controlled release of formic acid, HCOOH, by a cell or a tissue.
46722	lactic acid secretion	P	The controlled release of lactic acid, 2-hydroxypropanoic acid, by a cell or a tissue.
46723	malic acid secretion	P	The controlled release of malic acid, hydroxybutanedioic (hydroxysuccinic) acid, by a cell or a tissue.
46724	oxalic acid secretion	P	The controlled release of oxalic acid, ethanedioic acid, by a cell or a tissue.
46725	negative regulation by virus of viral protein levels in host cell	P	Any process where the infecting virus reduces the levels of viral proteins in a cell.
46726	positive regulation by virus of viral protein levels in host cell	P	Any process where the infecting virus increases the levels of viral proteins in a cell.
46727	capsomere	C	Any of the protein subunits that comprise the closed shell or coat (capsid) of certain viruses.
46729	viral procapsid	C	A stable empty viral capsid produced during the assembly of viruses.
46730	induction of host immune response by virus	P	The induction by a virus of an immune response in the host organism.
46731	passive induction of host immune response by virus	P	The unintentional stimulation by a virus of a host defense response to viral infection, as part of the viral infectious cycle.
46732	active induction of host immune response by virus	P	The intentional, virally-encoded stimulation of a host defense response to viral infection.
46733	passive induction of host humoral immune response by virus	P	The unintentional stimulation by a virus of a host humoral defense response to viral infection, as part of the viral infectious cycle.
46734	passive induction of host cell-mediated immune response by virus	P	The unintentional stimulation by a virus of a cell-mediated host defense response to viral infection, as part of the viral infectious cycle.
46735	passive induction of host innate immune response by virus	P	The unintentional stimulation by a virus of an innate host defense response to viral infection, as part of the viral infectious cycle.
46736	active induction of humoral immune response in host by virus	P	The intentional, virally-encoded stimulation of a host humoral defense response to viral infection.
46737	active induction of cell-mediated immune response in host by virus	P	The intentional, virally-encoded stimulation of a cell-mediated host defense response to viral infection.
46738	active induction of innate immune response in host by virus	P	The intentional, virally-encoded stimulation of an innate host defense response to viral infection.
46739	transport of virus in multicellular host	P	The transport of a virus between cells in a multicellular organism. The cells can be adjacent or spatially separated (e.g. in different tissues or organs).
46740	transport of virus in host, cell to cell	P	The transport of a virus between adjacent cells in a multicellular organism.
46741	transport of virus in host, tissue to tissue	P	The transport of a virus between tissues in a multicellular organism.
46745	viral capsid secondary envelopment	P	The process in which a capsid acquires another membrane envelope, subsequent to acquiring an initial membrane envelope.
46752	viral capsid precursor transport to host cell nucleus	P	Any process in which viral capsid precursors are transported to a specific location in the nucleus, thus accumulating the necessary components for assembly of a capsid.
46753	non-lytic viral release	P	The exit of a viral particle from a cell that does not involve cell lysis.
46754	viral exocytosis	P	The exit of enveloped or unenveloped virion particles from the host cell by exocytosis, without causing cell lysis.
46755	viral budding	P	A viral process by which enveloped viruses acquire a host-derived membrane enriched in viral proteins to form their external envelope. The process starts when nucleocapsids, assembled or in the process of being built, induce formation of a membrane curvature in the host plasma or organelle membrane and wrap up in the forming bud. The process ends when the bud is eventually pinched off by membrane scission to release the enveloped particle into the lumenal or extracellular space.
46760	viral budding from Golgi membrane	P	A viral budding that starts with formation of a membrane curvature in the host Golgi membrane.
46761	viral budding from plasma membrane	P	A viral budding that starts with formation of a membrane curvature in the host plasma membrane.
46762	viral budding from ER membrane	P	A viral budding that starts with formation of a membrane curvature in the host ER membrane.
46765	viral budding from nuclear membrane	P	A viral budding that starts with formation of a membrane curvature in the host nuclear membrane.
46771	viral budding from inner nuclear membrane	P	The envelopment of a virus, in which the nucleocapsid evaginates from the host inner nuclear membrane system into the perinuclear space, thus acquiring a membrane envelope.
46772	viral budding from outer nuclear membrane	P	The envelopment of a virus, in which the nucleocapsid evaginates from the host outer nuclear membrane system, thus acquiring a membrane envelope.
46773	suppression by virus of host translation termination	P	Any viral process that stops, prevents, or reduces the frequency, rate or extent of translational termination of a host mRNA.
46774	suppression by virus of host intracellular interferon activity	P	Any viral process that results in the inhibition of interferon activity within the host cell.
46775	suppression by virus of host cytokine production	P	Any viral process that results in the inhibition of host cell cytokine production.
46776	suppression by virus of host antigen processing and presentation of peptide antigen via MHC class I	P	Any viral process that inhibits a host antigen-presenting cell expressing a peptide antigen on its cell surface in association with an MHC class I protein complex. Class I here refers to classical class I molecules.
46777	protein autophosphorylation	P	The phosphorylation by a protein of one or more of its own amino acid residues (cis-autophosphorylation), or residues on an identical protein (trans-autophosphorylation).
46778	modification by virus of host mRNA processing	P	Any viral process that interferes with the processing of mRNA in the host cell.
46779	suppression by virus of expression of host genes with introns	P	Any viral process that discriminates against and subsequently inhibits host transcripts containing introns, thus allowing only intronless viral mRNA to be fully processed.
46780	suppression by virus of host mRNA splicing	P	Any viral process that inhibits the splicing of host mRNA, thus reducing host protein production.
46782	regulation of viral transcription	P	Any process that modulates the frequency, rate or extent of the transcription of the viral genome.
46783	modification by virus of host polysomes	P	Any viral process that interferes with and inhibits the assembly and function of polysomes.
46784	viral mRNA export from host cell nucleus	P	The directed movement of intronless viral mRNA from the host nucleus to the cytoplasm for translation.
46785	microtubule polymerization	P	The addition of tubulin heterodimers to one or both ends of a microtubule.
46786	viral replication complex formation and maintenance	P	The process of organizing and assembling viral replication proteins in preparation for viral replication.
46787	viral DNA repair	P	The process of restoring viral DNA after damage or errors in replication.
46789	host cell surface receptor binding	F	Interacting selectively and non-covalently with a receptor on the host cell surface.
46790	virion binding	F	Interacting selectively and non-covalently with a virion, either by binding to components of the capsid or the viral envelope.
46792	suppression by virus of host cell cycle arrest	P	Viral interference in host cell processes that lead cell cycle arrest, allowing cell division to occur.
46793	induction by virus of phosphorylation of host RNA polymerase II	P	Any process in which a virus activates the frequency, rate or extent of phosphorylation of host RNA polymerase II.
46794	transport of virus	P	The directed movement of a virus, or part of a virus, into, out of, or within a host cell.
46797	viral procapsid maturation	P	The refolding and structural rearrangements of individual capsid subunits to transition from the intermediate procapsid, to the more stable capsid structure.
46798	viral portal complex	C	A multimeric ring of proteins through which the DNA enters and exits the viral capsid.
46799	recruitment of helicase-primase complex to DNA lesions	P	The recruitment of the helicase-primase complex to viral DNA lesions during viral DNA repair.
46802	exit of virus from host cell nucleus by nuclear egress	P	The directed movement of an assembled viral particle out of the host cell nucleus by budding and fusion through the nuclear membranes. In this process, enveloped viral particles are formed by budding through the inner nuclear membrane. These perinuclear enveloped particles then fuse with the outer nuclear membrane to deliver a naked capsid into the host cytoplasm.
46804	peptide cross-linking via (2S,3S,4Xi,6R)-3-methyl-lanthionine sulfoxide	P	The formation of a protein-protein cross-link between peptidyl-threonine and peptidyl-cysteine by the synthesis of (2S,3S,4Xi,6R)-3-methyl-lanthionine sulfoxide (3-methyl-L-lanthionine sulfoxide), as found in the antibiotic actagardine.
46805	protein-heme linkage via 1'-L-histidine	P	The covalent linkage of heme and a protein via 1'-L-histidine (otherwise known as tau-heme-histidine, tele-heme-histidine).
46806	viral scaffold	C	A complex of proteins that form a scaffold around which the viral capsid is constructed.
46807	viral scaffold assembly and maintenance	P	The assembly and maintenance of the viral scaffold around which the viral capsid is constructed.
46808	assemblon	C	Antigenically dense structures located at the periphery of nuclei, close to but not abutting nuclear membranes. Assemblons contain the proteins for immature-capsid assembly; they are located at the periphery of a diffuse structure composed of proteins involved in DNA synthesis, which overlaps only minimally with the assemblons. More than one site can be present simultaneously.
46809	replication compartment	C	Globular nuclear domains where the transcription and replication of the viral genome occurs. More than one site can be present simultaneously.
46810	host cell extracellular matrix binding	F	Interacting selectively and non-covalently with the extracellular matrix of a host cell.
46811	histone deacetylase inhibitor activity	F	Stops, prevents or reduces the activity of histone deacetylase, which catalyzes of the removal of acetyl groups from histones, proteins complexed to DNA in chromatin and chromosomes.
46812	host cell surface binding	F	Interacting selectively and non-covalently with the surface of a host cell.
46813	receptor-mediated virion attachment to host cell	P	The process by which a virion attaches to a host cell by binding to a receptor on the host cell surface.
46814	coreceptor-mediated virion attachment to host cell	P	The process by which a virion attaches to a host cell by binding to a co-receptor on the host cell surface.
46815	genome retention in viral capsid	P	Any process in which the viral genome is retained within the capsid during genome cleavage and packaging.
46816	virion transport vesicle	C	A vesicle used to transport the partial or complete virion between cellular compartments.
46817	chemokine receptor antagonist activity	F	Interacts with chemokine receptors to reduce the action of a chemokine.
46818	dense nuclear body	C	A location in the host cell nucleus where viral proteins colocalize late in infection prior to the onset of viral DNA synthesis. More than one site can be present simultaneously.
46819	protein secretion by the type V secretion system	P	The process in which proteins mediate their own secretion across the outer membrane through a beta-barrel pore structure formed by the C-terminal domain of the protein precursor. Following passage across the outer membrane, the mature protein is released from the pore by an autocatalytic activity. Proteins secreted by the Type V system are first translocated across the plasma membrane by the Sec pathway.
46820	4-amino-4-deoxychorismate synthase activity	F	Catalysis of the reaction: L-glutamine + chorismate = 4-amino-4-deoxychorismate + L-glutamate. It is composed of two enzymatic activities (which may be present on one or two polypeptides); the first is a glutaminase which yields ammonia from glutamine, releasing glutamate. The ammonia is used by the second activity which catalyzes the amination of chorismate to form 4-amino-4-deoxychorismate.
46821	extrachromosomal DNA	C	DNA structures that are not part of a chromosome.
46822	regulation of nucleocytoplasmic transport	P	Any process that modulates the frequency, rate or extent of the directed movement of substances between the nucleus and the cytoplasm.
46823	negative regulation of nucleocytoplasmic transport	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of substances between the cytoplasm and the nucleus.
46824	positive regulation of nucleocytoplasmic transport	P	Any process that activates or increases the frequency, rate or extent of the directed movement of substances between the nucleus and the cytoplasm.
46825	regulation of protein export from nucleus	P	Any process that modulates the frequency, rate or extent of the directed movement of proteins from the nucleus to the cytoplasm.
46826	negative regulation of protein export from nucleus	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of proteins from the nucleus into the cytoplasm.
46827	positive regulation of protein export from nucleus	P	Any process that activates or increases the frequency, rate or extent of directed movement of proteins from the nucleus into the cytoplasm.
46828	regulation of RNA import into nucleus	P	Any process that modulates the frequency, rate or extent of movement of RNA from the cytoplasm to the nucleus.
46829	negative regulation of RNA import into nucleus	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the movement of RNA from the cytoplasm into the nucleus.
46830	positive regulation of RNA import into nucleus	P	Any process that activates or increases the frequency, rate or extent of movement of RNA from the cytoplasm into the nucleus.
46831	regulation of RNA export from nucleus	P	Any process that modulates the frequency, rate or extent of the directed movement of RNA from the nucleus to the cytoplasm.
46832	negative regulation of RNA export from nucleus	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of RNA from the nucleus into the cytoplasm.
46833	positive regulation of RNA export from nucleus	P	Any process that activates or increases the frequency, rate or extent of directed movement of RNA from the nucleus into the cytoplasm.
46834	lipid phosphorylation	P	The process of introducing one or more phosphate groups into a lipid, any member of a group of substances soluble in lipid solvents but only sparingly soluble in aqueous solvents.
46835	carbohydrate phosphorylation	P	The process of introducing a phosphate group into a carbohydrate, any organic compound based on the general formula Cx(H2O)y.
46836	glycolipid transport	P	The directed movement of glycolipids, compounds containing (usually) 1-4 linked monosaccharide residues joined by a glycosyl linkage to a lipid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
46838	phosphorylated carbohydrate dephosphorylation	P	The process of removing a phosphate group from a phosphorylated carbohydrate, any organic compound based on the general formula Cx(H2O)y with a phosphate group attached to it.
46839	phospholipid dephosphorylation	P	The process of removing one or more phosphate groups from a phosphorylated lipid, any member of a group of substances soluble in lipid solvents but only sparingly soluble in aqueous solvents.
46841	trisporic acid metabolic process	P	The chemical reactions and pathways involving trisporic acid, a carotenoic acid derivative used as a pheromone in some species of Zygomycota.
46842	trisporic acid biosynthetic process	P	The chemical reactions and pathways resulting in the formation of trisporic acid.
46843	dorsal appendage formation	P	Establishment of the dorsal filaments, elaborate specializations of the chorion that protrude from the anterior end of the egg and facilitate embryonic respiration.
46844	micropyle formation	P	Establishment of the micropyle, a single cone-shaped specialization of the chorion that allows sperm entry into the egg prior to fertilization.
46845	branched duct epithelial cell fate determination, open tracheal system	P	Allocation of a set number of cells to each primary branch in an open tracheal system, prior to the onset of cell migration. This establishes different domains of cells within the tracheal placode.
46847	filopodium assembly	P	The assembly of a filopodium, a thin, stiff protrusion extended by the leading edge of a motile cell such as a crawling fibroblast or amoeba, or an axonal growth cone.
46848	hydroxyapatite binding	F	Interacting selectively and non-covalently with hydroxyapatite, the calcium phosphate mineral of formula Ca10(PO4)6(OH)2 found both in rocks of nonorganic origin and as a component of bone and dentin.
46849	bone remodeling	P	The continuous turnover of bone matrix and mineral that involves first, an increase in resorption (osteoclastic activity) and later, reactive bone formation (osteoblastic activity). The process of bone remodeling takes place in the adult skeleton at discrete foci. The process ensures the mechanical integrity of the skeleton throughout life and plays an important role in calcium homeostasis. An imbalance in the regulation of bone resorption and bone formation results in many of the metabolic bone diseases, such as osteoporosis.
46850	regulation of bone remodeling	P	Any process that modulates the frequency, rate or extent of bone remodeling, the processes of bone formation and resorption that combine to maintain skeletal integrity.
46851	negative regulation of bone remodeling	P	Any process that stops, prevents, or reduces the frequency, rate or extent of bone remodeling.
46852	positive regulation of bone remodeling	P	Any process that activates or increases the frequency, rate or extent of bone remodeling.
46854	phosphatidylinositol phosphorylation	P	The process of introducing one or more phosphate groups into a phosphatidylinositol, any glycerophosphoinositol having one phosphatidyl group esterified to one of the hydroxy groups of inositol.
46855	inositol phosphate dephosphorylation	P	The process of removing a phosphate group from any mono- or polyphosphorylated inositol.
46856	phosphatidylinositol dephosphorylation	P	The process of removing one or more phosphate groups from a phosphatidylinositol.
46857	oxidoreductase activity, acting on other nitrogenous compounds as donors, with NAD or NADP as acceptor	F	Catalysis of an oxidation-reduction (redox) reaction in which a nitrogenous group, excluding NH and NH2 groups, acts as a hydrogen or electron donor and reduces NAD or NADP.
46858	chlorosome	C	A large enclosure of aggregated pigment, typically bacteriochlorophyll c (BChl c), that acts as a light-harvesting antenna structure and is characteristic of green photosynthetic bacteria (e.g. Chlorobiaceae). The BChl aggregates are organized into lamellar elements by pigment-pigment rather than pigment-protein interactions. Chlorosomes also contain BChl a, carotenoids, quinones, lipids, and proteins, and are attached to the cytoplasmic membrane via a BChl a-containing protein baseplate.
46859	hydrogenosomal membrane	C	The lipid bilayer surrounding a hydrogenosome.
46860	glycosome membrane	C	The lipid bilayer surrounding a glycosome.
46861	glyoxysomal membrane	C	The lipid bilayer surrounding a glyoxysome.
46862	chromoplast membrane	C	Either of the lipid bilayers that surround a chromoplast and form the chromoplast envelope.
46863	ribulose-1,5-bisphosphate carboxylase/oxygenase activator activity	F	Increases the activity of rubisco by the removal of otherwise inhibitory sugar phosphates: RuBP, and in some plants, 2-carboxyarabinitol 1-phosphate.
46864	isoprenoid transport	P	The directed movement of isoprenoids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Isoprenoids comprise a group of compounds containing or derived from linked isoprene (3-methyl-2-butenylene) residues.
46865	terpenoid transport	P	The directed movement of terpenoids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Terpenoids are a class of compounds characterized by an isoprenoid chemical structure and include derivatives with various functional groups.
46866	tetraterpenoid transport	P	The directed movement of tetraterpenoids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Tetraterpenoids are terpenoids with eight isoprene units.
46867	carotenoid transport	P	The directed movement of carotenoids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Carotenoids are tetraterpenoid compounds in which two units of 4 isoprenoid residues joined head-to-tail are themselves joined tail-to-tail.
46868	mesosome	C	An intracellular, often complex, membranous structure, sometimes with additional membranous lamellae inside, found in bacteria. They are associated with synthesis of DNA and secretion of proteins.
46869	iron incorporation into iron-sulfur cluster via tris-L-cysteinyl-L-aspartato diiron disulfide	P	The incorporation of iron into a 2Fe-2S iron-sulfur cluster via tris-L-cysteinyl-L-aspartato diiron disulfide.
46870	cadmium ion binding	F	Interacting selectively and non-covalently with cadmium (Cd) ions.
46871	N-acetylgalactosamine binding	F	Interacting selectively and non-covalently with N-acetylgalactosamine, 2-acetamido-2-deoxygalactopyranose, the n-acetyl derivative of galactosamine.
46872	metal ion binding	F	Interacting selectively and non-covalently with any metal ion.
46873	metal ion transmembrane transporter activity	F	Enables the transfer of metal ions from one side of a membrane to the other.
46874	quinolinate metabolic process	P	The chemical reactions and pathways involving quinolinate, the anion of quinolinic acid, also known as 2,3-pyridinedicarboxylic acid.
46875	ephrin receptor binding	F	Interacting selectively and non-covalently with an ephrin receptor.
46876	3,4-didehydroretinal binding	F	Interacting selectively and non-covalently with 3,4-didehydroretinal, a form of retinal that plays a role in the visual process in freshwater fish and some amphibians analogous to that of all-trans retinal in other vertebrates. 3,4-didehydro-11-cis-retinal combines with an opsin to form cyanopsin (cone) or porphyropsin (rod).
46877	regulation of saliva secretion	P	Any process that modulates the frequency, rate or extent of the regulated release of saliva from a cell or a tissue.
46878	positive regulation of saliva secretion	P	Any process that activates or increases the frequency, rate or extent of the regulated release of saliva.
46879	hormone secretion	P	The regulated release of hormones, substances with a specific regulatory effect on a particular organ or group of cells.
46880	regulation of follicle-stimulating hormone secretion	P	Any process that modulates the frequency, rate or extent of the regulated release of follicle-stimulating hormone.
46881	positive regulation of follicle-stimulating hormone secretion	P	Any process that activates or increases the frequency, rate or extent of the regulated release of follicle-stimulating hormone.
46882	negative regulation of follicle-stimulating hormone secretion	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of follicle-stimulating hormone.
46883	regulation of hormone secretion	P	Any process that modulates the frequency, rate or extent of the regulated release of a hormone from a cell.
46884	follicle-stimulating hormone secretion	P	The regulated release of follicle-stimulating hormone, a gonadotropic glycoprotein hormone secreted by the anterior pituitary.
46885	regulation of hormone biosynthetic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of hormones.
46886	positive regulation of hormone biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of hormones.
46887	positive regulation of hormone secretion	P	Any process that activates or increases the frequency, rate or extent of the regulated release of a hormone from a cell.
46888	negative regulation of hormone secretion	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a hormone from a cell.
46889	positive regulation of lipid biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of lipids.
46890	regulation of lipid biosynthetic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of lipids.
46891	peptidyl-cysteine S-carbamoylation	P	The carbamoylation of peptidyl-cysteine to form peptidyl-S-carbamoyl-L-cysteine.
46892	peptidyl-S-carbamoyl-L-cysteine dehydration	P	The dehydration of peptidyl-S-carbamoyl-L-cysteine to form peptidyl-S-cyano-L-cysteine.
46893	iron incorporation into hydrogenase diiron subcluster via L-cysteine ligation	P	The incorporation of iron into an L-cysteinyl diiron subcluster, found in Fe-hydrogenase.
46894	enzyme active site formation via S-amidino-L-cysteine	P	Active site formation via the transient amidinylation of peptidyl-cysteine to form peptidyl-S-amidino-L-cysteine.
46895	N-terminal peptidyl-isoleucine methylation	P	The methylation of the N-terminal isoleucine of proteins to form the derivative N-methyl-L-isoleucine.
46896	N-terminal peptidyl-leucine methylation	P	The methylation of the N-terminal leucine of proteins to form the derivative N-methyl-L-leucine.
46897	N-terminal peptidyl-tyrosine methylation	P	The methylation of the N-terminal tyrosine of proteins to form the derivative N-methyl-L-tyrosine.
46898	response to cycloheximide	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cycloheximide stimulus. Cycloheximide (actidione) is an antibiotic produced by some Streptomyces species which interferes with protein synthesis in eukaryotes.
46899	nucleoside triphosphate adenylate kinase activity	F	Catalysis of the reaction: nucleoside triphosphate + AMP = nucleoside diphosphate + ADP.
46900	tetrahydrofolylpolyglutamate metabolic process	P	The chemical reactions and pathways involving tetrahydrofolylpolyglutamate, a folate derivative comprising tetrahydrofolate attached to a chain of glutamate residues.
46901	tetrahydrofolylpolyglutamate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of tetrahydrofolylpolyglutamate, a folate derivative comprising tetrahydrofolate attached to a chain of glutamate residues.
46902	regulation of mitochondrial membrane permeability	P	Any process that modulates the frequency, rate or extent of the passage or uptake of molecules by the mitochondrial membrane.
46903	secretion	P	The controlled release of a substance by a cell or a tissue.
46904	calcium oxalate binding	F	Interacting selectively and non-covalently with calcium oxalate, CaC2O4, a salt of oxalic acid. In animals, it may be excreted in urine or retained in the form of urinary calculi.
46905	phytoene synthase activity	F	Catalysis of the reaction: prephytoene pyrophosphate = phytoene + diphosphate.
46906	tetrapyrrole binding	F	Interacting selectively and non-covalently with a tetrapyrrole, a compound containing four pyrrole nuclei variously substituted and linked to each other through carbons at the alpha position.
46907	intracellular transport	P	The directed movement of substances within a cell.
46909	intermembrane transport	P	The directed movement of substances between any membrane of a cell, including the plasma membrane and its regions.
46910	pectinesterase inhibitor activity	F	Stops, prevents or reduces the activity of any pectinesterase enzyme.
46911	metal chelating activity	F	The formation of bonds from two or more atoms within the same ligand to a metal atom in complexes in which the metal is part of a ring.
46912	transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer	F	Catalysis of the transfer of an acyl group from one compound (donor) to another (acceptor), with the acyl group being converted into alkyl on transfer.
46914	transition metal ion binding	F	Interacting selectively and non-covalently with a transition metal ions; a transition metal is an element whose atom has an incomplete d-subshell of extranuclear electrons, or which gives rise to a cation or cations with an incomplete d-subshell. Transition metals often have more than one valency state. Biologically relevant transition metals include vanadium, manganese, iron, copper, cobalt, nickel, molybdenum and silver.
46915	transition metal ion transmembrane transporter activity	F	Enables the transfer of transition metal ions from one side of a membrane to the other. A transition metal is an element whose atom has an incomplete d-subshell of extranuclear electrons, or which gives rise to a cation or cations with an incomplete d-subshell. Transition metals often have more than one valency state. Biologically relevant transition metals include vanadium, manganese, iron, copper, cobalt, nickel, molybdenum and silver.
46916	cellular transition metal ion homeostasis	P	Any process involved in the maintenance of an internal steady state of transition metal ions at the level of a cell. A transition metal is an element whose atom has an incomplete d-subshell of extranuclear electrons, or which gives rise to a cation or cations with an incomplete d-subshell. Transition metals often have more than one valency state. Biologically relevant transition metals include vanadium, manganese, iron, copper, cobalt, nickel, molybdenum and silver.
46917	triphosphoribosyl-dephospho-CoA synthase activity	F	Catalysis of the reaction: ATP + 3-dephospho-CoA = 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA + adenine.
46918	N-terminal peptidyl-glycine N-palmitoylation	P	The covalent attachment of a palmitoyl group to a nitrogen (N) atom in an N-terminal glycine residue to form N-palmitoyl-glycine.
46919	pyruvyltransferase activity	F	Catalysis of the transfer of a pyruvyl (oxopropanoyl) group from one compound to another.
46920	alpha-(1->3)-fucosyltransferase activity	F	Catalysis of the transfer of an L-fucosyl group from GDP-beta-L-fucose to an acceptor molecule to form an alpha-(1->3) linkage.
46921	alpha-(1->6)-fucosyltransferase activity	F	Catalysis of the transfer of an L-fucosyl group from GDP-beta-L-fucose to an acceptor molecule to form an alpha-(1->6) linkage.
46922	peptide-O-fucosyltransferase activity	F	Catalysis of the transfer of an alpha-L-fucosyl residue from GDP- beta-L-fucose to the serine hydroxy group of a protein acceptor.
46923	ER retention sequence binding	F	Interacting selectively and non-covalently with an endoplasmic reticulum (ER) retention sequence, a specific peptide sequence that ensures a protein is retained within the ER.
46924	peptide cross-linking via 2-(S-L-cysteinyl)-L-phenylalanine	P	The cross-linking of a cysteine residue to an L-phenylalanine residue to form 2-(S-L-cysteinyl)-L-phenylalanine.
46925	peptide cross-linking via 2-(S-L-cysteinyl)-D-phenylalanine	P	The cross-linking of a cysteine residue to an L-phenylalanine residue to form 2-(S-L-cysteinyl)-D-phenylalanine.
46926	peptide cross-linking via 2-(S-L-cysteinyl)-D-allo-threonine	P	The post-translational cross-linking of a cysteine residue to an L-threonine residue to form 2-(S-L-cysteinyl)-D-allo-threonine.
46927	peptidyl-threonine racemization	P	The racemization of peptidyl-L-threo-threonine at the alpha-carbon to form D-allo-threonine. This is coupled with the formation of the cross-link 2-(S-L-cysteinyl)-D-allo-threonine.
46928	regulation of neurotransmitter secretion	P	Any process that modulates the frequency, rate or extent of the regulated release of a neurotransmitter from a cell.
46929	negative regulation of neurotransmitter secretion	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of a neurotransmitter.
46930	pore complex	C	Any small opening in a membrane that allows the passage of gases and/or liquids.
46931	pore complex assembly	P	The aggregation, arrangement and bonding together of a set of components to form a pore complex. A pore complex is a small opening in a membrane that allows the passage of liquids and/or gases.
46932	sodium-transporting ATP synthase activity, rotational mechanism	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ADP + phosphate + Na+(out) = ATP + H2O + Na+(in), by a rotational mechanism.
46933	proton-transporting ATP synthase activity, rotational mechanism	F	Catalysis of the transfer of protons from one side of a membrane to the other according to the reaction: ADP + H2O + phosphate + H+(in) = ATP + H+(out), by a rotational mechanism.
46934	phosphatidylinositol-4,5-bisphosphate 3-kinase activity	F	Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + ATP = a 1-phosphatidyl-1D-myo-inositol 3,4,5-trisphosphate + ADP + 2 H(+).
46935	1-phosphatidylinositol-3-kinase regulator activity	F	Modulates the activity of the enzyme 1-phosphatidylinositol-3-kinase activity.
46936	deoxyadenosine deaminase activity	F	Catalysis of the reaction: deoxyadenosine + H2O = deoxyinosine + NH3.
46937	phytochelatin metabolic process	P	The chemical reactions and pathways involving phytochelatins, any of a group of peptides that bind metals (Cd, Zn, Cu, Pb, Hg) in thiolate coordination complexes. The structure is of the type (gamma-glutamyl-cysteinyl)n-glycine, where n is 2 to 11.
46938	phytochelatin biosynthetic process	P	The chemical reactions and pathways resulting in the formation of phytochelatins, any of a group of peptides that bind metals (Cd, Zn, Cu, Pb, Hg) in thiolate coordination complexes. The structure is of the type (gamma-glutamyl-cysteinyl)n-glycine, where n is 2 to 11.
46939	nucleotide phosphorylation	P	The process of introducing one or more phosphate groups into a nucleotide to produce a phosphorylated nucleoside.
46940	nucleoside monophosphate phosphorylation	P	The process of introducing one or more phosphate groups into a nucleoside monophosphate to produce a polyphosphorylated nucleoside.
46941	azetidine-2-carboxylic acid acetyltransferase activity	F	Catalysis of the reaction: L-azetidine-2-carboxylic acid + acetyl-CoA = CoA-SH + N-acetyl azetidine-2-carboxylic acid.
46942	carboxylic acid transport	P	The directed movement of carboxylic acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Carboxylic acids are organic acids containing one or more carboxyl (COOH) groups or anions (COO-).
46943	carboxylic acid transmembrane transporter activity	F	Enables the transfer of carboxylic acids from one side of the membrane to the other. Carboxylic acids are organic acids containing one or more carboxyl (COOH) groups or anions (COO-).
46944	protein carbamoylation	P	The addition of a carbamoyl group to a protein amino acid. A carbamoyl group is the acyl group -CO-NH2.
46945	N-terminal peptidyl-alanine N-carbamoylation	P	The carbamylation of the N-terminal alanine of proteins to form the derivative N-carbamoyl-L-alanine.
46946	hydroxylysine metabolic process	P	The chemical reactions and pathways involving hydroxylysine (5-hydroxy-2,6-diaminohexanoic acid), a chiral alpha-amino acid. Hydroxylysine is found in collagen and commonly has galactose and then glucose added sequentially by glycosyltransferases.
46947	hydroxylysine biosynthetic process	P	The chemical reactions and pathways resulting in the formation of hydroxylysine (5-hydroxy-2,6-diaminohexanoic acid), a chiral alpha-amino acid.
46948	hydroxylysine catabolic process	P	The chemical reactions and pathways resulting in the breakdown of hydroxylysine (5-hydroxy-2,6-diaminohexanoic acid), a chiral alpha-amino acid.
46949	fatty-acyl-CoA biosynthetic process	P	The chemical reactions and pathways resulting in the formation of a fatty-acyl-CoA, any derivative of coenzyme A in which the sulfhydryl group is in thiolester linkage with a fatty-acyl group.
46950	cellular ketone body metabolic process	P	The chemical reactions and pathways involving ketone bodies, any one of the three substances: acetoacetate, D-3-hydroxybutyrate (beta-hydroxybutyrate) or acetone, as carried out by individual cells. Although 3-hydroxybutyrate is not a ketone, it is classed as a ketone body because it exists in an equilibrium with acetoacetate. Ketone bodies may accumulate in excessive amounts in the body in starvation, diabetes mellitus or in other defects of carbohydrate metabolism.
46951	ketone body biosynthetic process	P	The chemical reactions and pathways resulting in the formation of ketone bodies, any one of the three substances: acetoacetate, D-3-hydroxybutyrate (beta-hydroxybutyrate) or acetone. Biosynthesis involves the formation of hydroxymethylglutaryl-CoA, which is cleaved to acetate and acetyl-CoA.
46952	ketone body catabolic process	P	The chemical reactions and pathways resulting in the breakdown of ketone bodies, any one of the three substances: acetoacetate, D-3-hydroxybutyrate (beta-hydroxybutyrate) or acetone. Ketone bodies can be used as an energy source as an alternative to glucose. Utilization of ketone bodies in peripheral tissues involves conversion of acetoacetate to acetoacetyl-CoA, which is then converted to two molecules of acetyl-CoA.
46956	positive phototaxis	P	The directed movement of a cell or organism towards a source of light.
46957	negative phototaxis	P	The directed movement of a cell or organism away from a source of light.
46958	nonassociative learning	P	A simple form of learning whereby the repeated presence of a stimulus leads to a change in the probability or strength of the response to that stimulus. There is no association of one type of stimulus with another, rather it is a generalized response to the environment.
46959	habituation	P	A decrease in a behavioral response to a repeated stimulus. This is exemplified by the failure of a person to show a startle response to a loud noise that has been repeatedly presented.
46960	sensitization	P	An increased in a behavioral response to a repeated stimulus. For example, a shock to the tail of the marine snail Aplysia, to which the snail responds by withdrawing its gill, will result in increased gill withdrawal the next time the skin is touched.
46961	proton-transporting ATPase activity, rotational mechanism	F	Catalysis of the transfer of protons from one side of a membrane to the other according to the reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out), by a rotational mechanism.
46962	sodium-transporting ATPase activity, rotational mechanism	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Na+(in) = ADP + phosphate + Na+(out), by a rotational mechanism.
46963	3'-phosphoadenosine 5'-phosphosulfate transport	P	The directed movement of 3'-phosphoadenosine 5'-phosphosulfate, a naturally occurring mixed anhydride synthesized from adenosine 5'-phosphosulfate, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
46964	3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity	F	Enables the transfer of 3'-phosphoadenosine 5'-phosphosulfate, a naturally occurring mixed anhydride synthesized from adenosine 5'-phosphosulfate, from one side of a membrane to the other.
46965	retinoid X receptor binding	F	Interacting selectively and non-covalently with a retinoid X receptor.
46966	thyroid hormone receptor binding	F	Interacting selectively and non-covalently with a thyroid hormone receptor.
46967	cytosol to ER transport	P	The directed movement of substances from the cytosol to the endoplasmic reticulum of a cell.
46968	peptide antigen transport	P	The directed movement of a peptide antigen into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. The peptide antigen is typically, but not always, processed from an endogenous or exogenous protein.
46969	NAD-dependent histone deacetylase activity (H3-K9 specific)	F	Catalysis of the reaction: histone H3 N6-acetyl-L-lysine (position 9) + H2O = histone H3 L-lysine (position 9) + acetate. This reaction requires the presence of NAD, and represents the removal of an acetyl group from lysine at position 9 of the histone H3 protein.
46970	NAD-dependent histone deacetylase activity (H4-K16 specific)	F	Catalysis of the reaction: histone H4 N6-acetyl-L-lysine (position 16) + H2O = histone H4 L-lysine (position 16) + acetate. This reaction requires the presence of NAD, and represents the removal of an acetyl group from lysine at position 16 of the histone H4 protein.
46972	histone acetyltransferase activity (H4-K16 specific)	F	Catalysis of the reaction: acetyl-CoA + histone H4 L-lysine (position 16) = CoA + histone H4 N6-acetyl-L-lysine (position 16). This reaction represents the addition of an acetyl group to the lysine at position 16 of histone H4.
46974	histone methyltransferase activity (H3-K9 specific)	F	Catalysis of the reaction: S-adenosyl-L-methionine + histone H3 L-lysine (position 9) = S-adenosyl-L-homocysteine + histone H3 N6-methyl-L-lysine (position 9). This reaction is the addition of a methyl group onto lysine at position 9 of the histone H3 protein.
46975	histone methyltransferase activity (H3-K36 specific)	F	Catalysis of the reaction: S-adenosyl-L-methionine + histone H3 L-lysine (position 36) = S-adenosyl-L-homocysteine + histone H3 N6-methyl-L-lysine (position 36). This reaction is the addition of a methyl group onto lysine at position 36 of the histone H3 protein.
46976	histone methyltransferase activity (H3-K27 specific)	F	Catalysis of the reaction: S-adenosyl-L-methionine + histone H3 L-lysine (position 27) = S-adenosyl-L-homocysteine + histone H3 N6-methyl-L-lysine (position 27). This reaction is the addition of a methyl group onto lysine at position 27 of the histone H3 protein.
46977	TAP binding	F	Interacting selectively and non-covalently with TAP protein, transporter associated with antigen processing protein. TAP protein is a heterodimeric peptide transporter consisting of the subunits TAP1 and TAP2.
46978	TAP1 binding	F	Interacting selectively and non-covalently with the TAP1 subunit of TAP (transporter associated with antigen processing) protein.
46979	TAP2 binding	F	Interacting selectively and non-covalently with the TAP2 subunit of TAP (transporter associated with antigen processing) protein.
46980	tapasin binding	F	Interacting selectively and non-covalently with tapasin, a member of the MHC class I loading complex which bridges the TAP peptide transporter to class I molecules.
46981	beta-1,4-mannosylglycolipid beta-1,3-N-acetylglucosaminyltransferase activity	F	Catalysis of the transfer of N-acetylglucosamine (GlcNAc) in a beta-1,3 linkage to the mannose(beta-1,4)Glc disaccharide core of glycolipids.
46982	protein heterodimerization activity	F	Interacting selectively and non-covalently with a nonidentical protein to form a heterodimer.
46983	protein dimerization activity	F	The formation of a protein dimer, a macromolecular structure consists of two noncovalently associated identical or nonidentical subunits.
46984	regulation of hemoglobin biosynthetic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of hemoglobin, an oxygen carrying, conjugated protein containing four heme groups and globin.
46985	positive regulation of hemoglobin biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of hemoglobin, an oxygen carrying, conjugated protein containing four heme groups and globin.
46986	negative regulation of hemoglobin biosynthetic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of hemoglobin, an oxygen carrying, conjugated protein containing four heme groups and globin.
46987	N-acetyllactosamine beta-1,3-glucuronosyltransferase activity	F	Catalysis of the transfer, in a beta 1,3 linkage, of D-glucuronic acid (GlcUA) from UDP-D-glucuronic acid to N-acetyllactosamine (galactosyl beta-1,4-N-acetylglucosamine).
46988	asioloorosomucoid beta-1,3-glucuronosyltransferase activity	F	Catalysis of the transfer, in a beta 1,3 linkage, of D-glucuronic acid (GlcUA) from UDP-GlcUA to asioloorosomucoid.
46989	galactosyl beta-1,3 N-acetylgalactosamine beta-1,3-glucuronosyltransferase activity	F	Catalysis of the transfer, in a beta 1,3 linkage, of D-glucuronic acid (GlcUA) from UDP-GlcUA to the disaccharide galactosyl beta-1,3 N-acetylgalactosamine, a common component of glycoproteins and glycolipids.
46990	N-hydroxyarylamine O-acetyltransferase activity	F	Catalysis of the reaction: acetyl-CoA + an N-hydroxyarylamine = CoA + an N-acetoxyarylamine.
46992	oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond	F	Catalysis of an oxidation-reduction (redox) reaction in which X-H and Y-H form X-Y.
46993	oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond, with oxygen as acceptor	F	Catalysis of an oxidation-reduction (redox) reaction in which X-H and Y-H form X-Y and the acceptor is oxygen.
46994	oxidoreductase activity, acting on hydrogen as donor, with a quinone or similar compound as acceptor	F	Catalysis of an oxidation-reduction (redox) reaction in which hydrogen acts as an electron donor and reduces quinone or similar compound.
46995	oxidoreductase activity, acting on hydrogen as donor, with other known acceptors	F	Catalysis of an oxidation-reduction (redox) reaction in which hydrogen reduces a known acceptor other than a cytochrome, an iron-sulfur protein, NAD, NADP, or a quinone or similar compound.
46996	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, with NAD(P)H as one donor, and the other dehydrogenated	F	Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from NADH or NADPH and one other donor, and the latter donor is dehydrogenated.
46997	oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor	F	Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH group acts as a hydrogen or electron donor and reduces a flavin.
46998	(S)-usnate reductase activity	F	Catalysis of the reaction: (6R)-2-acetyl-6-(3-acetyl-2,4,6-trihydroxy-5-methylphenyl)-3-hydroxy-6-methylcyclohexa-2,4-dien-1-one + NAD(+) = (S)-usnate + 2 H(+) + NADH.
46999	regulation of conjugation	P	Any process that modulates the rate or frequency of conjugation, the union or introduction of genetic information from compatible mating types that results in a genetically different individual.
47000	2-dehydro-3-deoxy-D-gluconate 6-dehydrogenase activity	F	Catalysis of the reaction: 2-dehydro-3-deoxy-D-gluconate + NADP(+) = (4S,5S)-4,5-dihydroxy-2,6-dioxohexanoate + H(+) + NADPH.
47001	2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase activity	F	Catalysis of the reaction: NAD+ + 2-dehydro-3-deoxy-D-gluconate = NADH + (4S)-4,6-dihydroxy-2,5-dioxohexanoate.
47002	L-arabinitol 2-dehydrogenase activity	F	Catalysis of the reaction: L-arabinitol + NAD(+) = L-ribulose + H(+) + NADH.
47003	dTDP-6-deoxy-L-talose 4-dehydrogenase activity	F	Catalysis of the reaction: dTDP-6-deoxy-L-talose + NADP(+) = dTDP-4-dehydro-6-deoxy-L-mannose + H(+) + NADPH.
47004	UDP-N-acetylglucosamine 6-dehydrogenase activity	F	Catalysis of the reaction: H(2)O + 2 NAD(+) + UDP-N-acetyl-alpha-D-glucosamine = 3 H(+) + 2 NADH + UDP-N-acetyl-2-amino-2-deoxy-D-glucuronate.
47005	16-alpha-hydroxysteroid dehydrogenase activity	F	Catalysis of the reaction: NADP+ + 16-alpha-hydroxysteroid = NADPH + H+ + 16-oxosteroid.
47006	17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity	F	Catalysis of the reaction: NAD(P)+ + 17-alpha,20-alpha-dihydroxypregn-4-en-3-one = NAD(P)H + H+ + 17-alpha-hydroxyprogesterone.
47007	pregnan-21-ol dehydrogenase (NAD+) activity	F	Catalysis of the reaction: NAD(+) + pregnan-21-ol = H(+) + NADH + pregnan-21-al.
47008	pregnan-21-ol dehydrogenase (NADP+) activity	F	Catalysis of the reaction: NADP(+) + pregnan-21-ol = H(+) + NADPH + pregnan-21-al.
47009	3-alpha-hydroxy-5-beta-androstane-17-one 3-alpha-dehydrogenase activity	F	Catalysis of the reaction: NAD+ + 3-alpha-hydroxy-5-beta-androstane-17-one = NADH + H+ + 5-beta-androstane-3,17-dione.
47010	hydroxycyclohexanecarboxylate dehydrogenase activity	F	Catalysis of the reaction: (1S,3R,4S)-3,4-dihydroxycyclohexane-1-carboxylate + NAD(+) = (1S,4S)-4-hydroxy-3-oxocyclohexane-1-carboxylate + H(+) + NADH.
47011	2-dehydropantolactone reductase (A-specific) activity	F	Catalysis of the reaction: (R)-pantolactone + NADP+ = 2-dehydropantolactone + NADPH + H+. The reaction is A-specific (i.e. the pro-R hydrogen is transferred from the 4-position of reduced nicotinamide cofactor) with respect to NADP+.
47012	sterol-4-alpha-carboxylate 3-dehydrogenase (decarboxylating) activity	F	Catalysis of the reaction: NAD(P)+ + 3-beta-hydroxy-4-alpha-methyl-5-alpha-cholest-7-ene-4-beta-carboxylate = NAD(P)H + H+ + CO2 + 4-alpha-methyl-5-alpha-cholest-7-en-3-one.
47013	cholate 12-alpha dehydrogenase activity	F	Catalysis of the reaction: cholate + NADP(+) = 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanate + H(+) + NADPH.
47014	glycerol-3-phosphate 1-dehydrogenase [NADP+] activity	F	Catalysis of the reaction: sn-glycerol 3-phosphate + NADP(+) = D-glyceraldehyde 3-phosphate + H(+) + NADPH.
47015	3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity	F	Catalysis of the reaction: NAD+ + 2-methyl-3-hydroxybutyryl-CoA = NADH + H+ + 2-methylaceto-acetyl-CoA.
47016	cholest-5-ene-3-beta,7-alpha-diol 3-beta-dehydrogenase activity	F	Catalysis of the reaction: NAD+ + 7-alpha-hydroxycholesterol = NADH + H+ + 7-alpha-hydroxycholest-4-en-3-one.
47017	prostaglandin-F synthase activity	F	Catalysis of the reaction: NADP+ + (5Z,13E)-(15S)-9-alpha,11-alpha,15-trihydroxyprosta-5,13-dienoate = NADPH + H+ + (5Z,13E)-(15S)-9-alpha,15-dihydroxy-11-oxoprosta-5,13-dienoate.
47018	indole-3-acetaldehyde reductase (NADH) activity	F	Catalysis of the reaction: indole-3-ethanol + NAD(+) = (indol-3-yl)acetaldehyde + H(+) + NADH.
47019	indole-3-acetaldehyde reductase (NADPH) activity	F	Catalysis of the reaction: indole-3-ethanol + NADP(+) = (indol-3-yl)acetaldehyde + H(+) + NADPH.
47020	15-hydroxyprostaglandin-D dehydrogenase (NADP+) activity	F	Catalysis of the reaction: NADP+ + (5Z,13E)-(15S)-9-alpha,15-dihydroxy-11-oxoprosta-5,13-dienoate = NADPH + H+ + (5Z,13E)-9-alpha-hydroxy-11,15-dioxoprosta-5,13-dienoate.
47021	15-hydroxyprostaglandin dehydrogenase (NADP+) activity	F	Catalysis of the reaction: NADP(+) + prostaglandin E(1) = 15-dehydro-prostaglandin E1 + H(+) + NADPH.
47022	7-beta-hydroxysteroid dehydrogenase (NADP+) activity	F	Catalysis of the reaction: NADP+ + a 7-beta-hydroxysteroid = NADPH + H+ + a 7-oxosteroid.
47023	androsterone dehydrogenase activity	F	Catalysis of the reaction: NAD(P)+ + androsterone = NAD(P)H + H+ + 5-alpha-androstane-3,17-dione.
47024	5alpha-androstane-3beta,17beta-diol dehydrogenase activity	F	Catalysis of the reaction: 5alpha-androstane-3beta,17beta-diol + NADP(+) = 17beta-hydroxy-5alpha-androstan-3-one + H(+) + NADPH.
47025	3-oxoacyl-[acyl-carrier-protein] reductase (NADH) activity	F	Catalysis of the reaction: NAD+ + OH-acyl-[acyl-carrier protein] = NADH + H+ + B-ketoacyl-[acyl-carrier protein].
47026	androsterone dehydrogenase (A-specific) activity	F	Catalysis of the reaction: NAD(P)+ + androsterone = NAD(P)H + H+ + 5-alpha-androstane-3,17-dione. The reaction is A-specific (i.e. the pro-R hydrogen is transferred from the 4-position of reduced nicotinamide cofactor) with respect to NAD(P)+.
47027	benzyl-2-methyl-hydroxybutyrate dehydrogenase activity	F	Catalysis of the reaction: benzyl (2R,3S)-2-methyl-3-hydroxybutanoate + NADP(+) = benzyl 2-methyl-3-oxobutanoate + H(+) + NADPH.
47028	6-pyruvoyltetrahydropterin 2'-reductase activity	F	Catalysis of the reaction: NADP+ + 6-lactoyl-5,6,7,8-tetrahydropterin = NADPH + H+ + 6-pyruvoyltetrahydropterin.
47029	(R)-4-hydroxyphenyllactate dehydrogenase activity	F	Catalysis of the reaction: NAD(P)+ + (R)-3-(4-hydroxyphenyl)lactate = NAD(P)H + H+ + 3-(4-hydroxyphenyl)pyruvate.
47030	4-hydroxycyclohexanecarboxylate dehydrogenase activity	F	Catalysis of the reaction: trans-4-hydroxycyclohexanecarboxylate + NAD(+) = 4-oxocyclohexanecarboxylate + H(+) + NADH.
47031	diethyl 2-methyl-3-oxosuccinate reductase activity	F	Catalysis of the reaction: diethyl (2R,3R)-2-methyl-3-hydroxysuccinate + NADP(+) = diethyl 2-methyl-3-oxosuccinate + H(+) + NADPH.
47032	3-alpha-hydroxyglycyrrhetinate dehydrogenase activity	F	Catalysis of the reaction: 3alpha-hydroxyglycyrrhetinate + NADP(+) = 3-oxoglycyrrhetinate + H(+) + NADPH.
47033	15-hydroxyprostaglandin-I dehydrogenase (NADP+) activity	F	Catalysis of the reaction: NADP(+) + prostaglandin I(2) = 15-dehydro-prostaglandin I(2) + H(+) + NADPH.
47034	15-hydroxyicosatetraenoate dehydrogenase activity	F	Catalysis of the reaction: NAD(P)+ + (15S)-15-hydroxy-5,8,11-cis-13-trans-icosatetraenoate = NAD(P)H + H+ + 15-oxo-5,8,11-cis-13-trans-icosatetraenoate.
47035	testosterone dehydrogenase (NAD+) activity	F	Catalysis of the reaction: testosterone + NAD+ = androst-4-ene-3,17-dione + NADH.
47036	codeinone reductase (NADPH) activity	F	Catalysis of the reaction: codeine + NADP(+) = codeinone + H(+) + NADPH.
47037	salutaridine reductase (NADPH) activity	F	Catalysis of the reaction: (7S)-salutaridinol + NADP(+) = H(+) + NADPH + salutaridine.
47038	D-arabinitol 2-dehydrogenase activity	F	Catalysis of the reaction: D-arabinitol + NAD(+) = D-ribulose + H(+) + NADH.
47039	tetrahydroxynaphthalene reductase activity	F	Catalysis of the reaction: NADP+ + scytalone = NADPH + H+ + 1,3,6,8-naphthalenetetrol.
47040	pteridine reductase activity	F	Catalysis of the reaction: 5,6,7,8-tetrahydrobiopterin + 2 NADP(+) = biopterin + 2 H(+) + 2 NADPH.
47041	(S)-carnitine 3-dehydrogenase activity	F	Catalysis of the reaction: (S)-carnitine + NAD(+) = 3-dehydrocarnitine + H(+) + NADH.
47042	androsterone dehydrogenase (B-specific) activity	F	Catalysis of the reaction: NAD(P)+ + androsterone = NAD(P)H + H+ + 5-alpha-androstane-3,17-dione. The reaction is B-specific (i.e. the pro-S hydrogen is transferred from the 4-position of reduced nicotinamide cofactor) with respect to NAD(P)+.
47043	3-alpha-hydroxycholanate dehydrogenase activity	F	Catalysis of the reaction: lithocholate + NAD(+) = 3-oxo-5beta-cholanate + H(+) + NADH.
47044	androstan-3-alpha,17-beta-diol dehydrogenase activity	F	Catalysis of the reaction: NAD+ + androstan-3-alpha,17-beta-diol = 17-beta-hydroxyandrostan-3-one + NADH + H+.
47045	testosterone 17-beta-dehydrogenase (NADP+) activity	F	Catalysis of the reaction: NADP+ + testosterone = NADPH + H+ + androst-4-ene-3,17-dione.
47046	homoisocitrate dehydrogenase activity	F	Catalysis of the reaction: NAD+ + 3-carboxy-2-hydroxyadipate = NADH + H+ + CO2 + 2-keto-adipate.
47047	oxaloglycolate reductase (decarboxylating) activity	F	Catalysis of the reaction: glycerate + CO2 + NAD(P)+ = NAD(P)H + H+ + 2-hydroxy-3-oxosuccinate.
47048	3-hydroxybenzyl-alcohol dehydrogenase activity	F	Catalysis of the reaction: 3-hydroxybenzyl alcohol + NADP(+) = 3-hydroxybenzaldehyde + H(+) + NADPH.
47049	(R)-2-hydroxy-fatty acid dehydrogenase activity	F	Catalysis of the reaction: (R)-2-hydroxystearate + NAD(+) = 2-oxostearate + H(+) + NADH.
47050	(S)-2-hydroxy-fatty acid dehydrogenase activity	F	Catalysis of the reaction: (S)-2-hydroxystearate + NAD(+) = 2-oxostearate + H(+) + NADH.
47051	D-lactate dehydrogenase (cytochrome c-553) activity	F	Catalysis of the reaction: 2 ferricytochrome C-553 + D-lactate = 2 ferrocytochrome C-553 + pyruvate.
47052	(S)-stylopine synthase activity	F	Catalysis of the reaction: (S)-cheilanthifoline + H(+) + NADPH + O(2) = (S)-stylopine + 2 H(2)O + NADP(+).
47053	(S)-cheilanthifoline synthase activity	F	Catalysis of the reaction: (S)-scoulerine + H(+) + NADPH + O(2) = (S)-cheilanthifoline + 2 H(2)O + NADP(+).
47054	berbamunine synthase activity	F	Catalysis of the reaction: O2 + NADPH + H+ + R-N-methylcoclaurine + S-N-methylcoclaurine = 2 H2O + NADP+ + berbamunine.
47055	salutaridine synthase activity	F	Catalysis of the reaction: (R)-reticuline + H(+) + NADPH + O(2) = 2 H(2)O + NADP(+) + salutaridine.
47056	(S)-canadine synthase activity	F	Catalysis of the reaction: (S)-tetrahydrocolumbamine + H(+) + NADPH + O(2) = (S)-canadine + 2 H(2)O + NADP(+).
47057	vitamin-K-epoxide reductase (warfarin-sensitive) activity	F	Catalysis of the reaction: 2-methyl-3-phytyl-1,4-naphthoquinone + oxidized dithiothreitol + H2O = 2,3-epoxy-2,3-dihydro-2-methyl-3-phytyl-1,4-naphthoquinone + 1,4-dithiothreitol.
47058	vitamin-K-epoxide reductase (warfarin-insensitive) activity	F	Catalysis of the reaction: 3-hydroxy-2-methyl-3-phytyl-2,3-dihydronaphthoquinone + oxidized dithiothreitol + H2O = 2,3-epoxy-2,3-dihydro-2-methyl-3-phytyl-1,4-naphthoquinone + 1,4-dithiothreitol.
47059	polyvinyl alcohol dehydrogenase (cytochrome) activity	F	Catalysis of the reaction: polyvinyl alcohol + ferricytochrome c = oxidized polyvinyl alcohol + ferrocytochrome c + H+.
47060	(R)-pantolactone dehydrogenase (flavin) activity	F	Catalysis of the reaction: (R)-pantolactone + A = 2-dehydropantolactone + AH(2).
47061	glucose-fructose oxidoreductase activity	F	Catalysis of the reaction: D-fructose + D-glucose = D-glucitol + D-glucono-1,5-lactone.
47062	trans-acenaphthene-1,2-diol dehydrogenase activity	F	Catalysis of the reaction: (+-)-trans-acenaphthene-1,2-diol + 2 NADP(+) = acenaphthene-1,2-dione + 2 H(+) + 2 NADPH.
47063	L-ascorbate-cytochrome-b5 reductase activity	F	Catalysis of the reaction: ferricytochrome B5 + ascorbate = ferrocytochrome B5 + monodehydroascorbate.
47064	sulochrin oxidase [(+)-bisdechlorogeodin-forming] activity	F	Catalysis of the reaction: O(2) + 2 sulochrin = 2 (2S)-bisdechlorogeodin + 2 H(2)O.
47065	sulochrin oxidase [(-)-bisdechlorogeodin-forming] activity	F	Catalysis of the reaction: O(2) + 2 sulochrin = 2 (2R)-bisdechlorogeodin + 2 H(2)O.
47066	phospholipid-hydroperoxide glutathione peroxidase activity	F	Catalysis of the reaction: a lipid hydroperoxide + 2 reduced glutathione = 2 H2O + lipid + 2 oxidized glutathione.
47067	hydrogen:quinone oxidoreductase activity	F	Catalysis of the reaction: H(2) + menaquinone = reduced menaquinone.
47068	N5,N10-methenyltetrahydromethanopterin hydrogenase activity	F	Catalysis of the reaction: 5,10-methenyl-5,6,7,8-tetrahydromethanopterin + H(2) = 5,10-methylenetetrahydromethanopterin + H(+).
47069	7,8-dihydroxykynurenate 8,8a-dioxygenase activity	F	Catalysis of the reaction: 7,8-dihydroxykynurenate + O(2) = 5-(3-carboxylato-3-oxoprop-1-en-1-yl)-4,6-dihydroxypyridine-2-carboxylate + H(+).
47070	3-carboxyethylcatechol 2,3-dioxygenase activity	F	Catalysis of the reaction: O2 + 3-(2,3-dihydroxyphenyl)propanoate = 2-hydroxy-6-oxonona-2,4-diene-1,9-dioate.
47071	3,4-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione 4,5-dioxygenase activity	F	Catalysis of the reaction: 3,4-dihydroxy-9,10-secoandrosta-1,3,5(10)-triene-9,17-dione + O(2) = 3-hydroxy-5,9,17-trioxo-4,5:9,10-disecoandrosta-1(10),2-dien-4-oate + H(+).
47072	2,3-dihydroxybenzoate 2,3-dioxygenase activity	F	Catalysis of the reaction: 2,3-dihydroxybenzoate + O(2) = 2-carboxy-cis,cis-muconate + 2 H(+).
47073	2,4'-dihydroxyacetophenone dioxygenase activity	F	Catalysis of the reaction: 2,4'-dihydroxyacetophenone + O(2) = 4-hydroxybenzoate + formate + 2 H(+).
47074	4-hydroxycatechol 1,2-dioxygenase activity	F	Catalysis of the reaction: O2 + benzene-1,2,4-triol = maleylacetate.
47075	2,5-dihydroxypyridine 5,6-dioxygenase activity	F	Catalysis of the reaction: H2O + O2 + 2,5-dihydroxypyridine = formate + maleamate.
47077	Photinus-luciferin 4-monooxygenase (ATP-hydrolyzing) activity	F	Catalysis of the reaction: O2 + ATP + Photinus luciferin = light + diphosphate + AMP + CO2 + oxidized Photinus luciferin.
47078	3-hydroxy-4-oxoquinoline 2,4-dioxygenase activity	F	Catalysis of the reaction: O2 + 3-hydroxy-1H-quinolin-4-one = carbon monoxide + N-formylanthranilate.
47079	deoxyuridine 1'-dioxygenase activity	F	Catalysis of the reaction: 2'-deoxyuridine + 2-oxoglutarate + O(2) = 2-deoxy-D-ribono-1,4-lactone + CO(2) + succinate + uracil.
47080	deoxyuridine 2'-dioxygenase activity	F	Catalysis of the reaction: 2'-deoxyuridine + 2-oxoglutarate + O(2) = CO(2) + succinate + uridine.
47081	3-hydroxy-2-methylpyridinecarboxylate dioxygenase activity	F	Catalysis of the reaction: O2 + NAD(P)H + H+ + 3-hydroxy-2-methylpyridine-5-carboxylate = NAD(P)+ + 2-(acetamidomethylene)succinate.
47082	3,9-dihydroxypterocarpan 6a-monooxygenase activity	F	Catalysis of the reaction: (6aR,11aR)-3,9-dihydroxypterocarpan + H(+) + NADPH + O(2) = (6aS,11aS)-3,6a,9-trihydroxypterocarpan + H(2)O + NADP(+). (6aS,11aS)-3,6a,9-trihydroxypterocarpan is also known as (-)-glycinol.
47083	5-O-(4-coumaroyl)-D-quinate 3'-monooxygenase activity	F	Catalysis of the reaction: O2 + NADPH + H+ + trans-5-O-(4-coumaroyl)-D-quinate = H2O + NADP+ + trans-5-O-caffeoyl-D-quinate.
47084	methyltetrahydroprotoberberine 14-monooxygenase activity	F	Catalysis of the reaction: O2 + NADPH + H+ + (S)-N-methylcanadine = H2O + NADP+ + allocryptopine.
47085	hydroxyphenylacetonitrile 2-monooxygenase activity	F	Catalysis of the reaction: 4-hydroxyphenylacetonitrile + H(+) + NADPH + O(2) = 4-hydroxymandelonitrile + H(2)O + NADP(+).
47086	ketosteroid monooxygenase activity	F	Catalysis of the reaction: O2 + NADPH + progesterone = H2O + NADP+ + testosterone acetate.
47087	protopine 6-monooxygenase activity	F	Catalysis of the reaction: H(+) + NADPH + O(2) + protopine = 6-hydroxyprotopine + H(2)O + NADP(+).
47088	dihydrosanguinarine 10-monooxygenase activity	F	Catalysis of the reaction: dihydrosanguinarine + H(+) + NADPH + O(2) = 10-hydroxydihydrosanguinarine + H(2)O + NADP(+).
47089	dihydrochelirubine 12-monooxygenase activity	F	Catalysis of the reaction: dihydrochelirubine + H(+) + NADPH + O(2) = 12-hydroxydihydrochelirubine + H(2)O + NADP(+).
47090	benzoyl-CoA 3-monooxygenase activity	F	Catalysis of the reaction: benzoyl-CoA + H(+) + NADPH + O(2) = 3-hydroxybenzoyl-CoA + H(2)O + NADP(+).
47091	L-lysine 6-monooxygenase (NADPH) activity	F	Catalysis of the reaction: L-lysine + NADPH + O(2) = N(6)-hydroxy-L-lysine + H(2)O + NADP(+).
47092	27-hydroxycholesterol 7-alpha-monooxygenase activity	F	Catalysis of the reaction: O2 + NADPH + 27-hydroxycholesterol = H2O + NADP+ + 7-alpha,27-dihydroxycholesterol.
47093	4-hydroxyquinoline 3-monooxygenase activity	F	Catalysis of the reaction: H(+) + NADH + O(2) + quinolin-4-ol = H(2)O + NAD(+) + quinoline-3,4-diol.
47094	3-hydroxyphenylacetate 6-hydroxylase activity	F	Catalysis of the reaction: O2 + NAD(P)H + 3-hydroxyphenylacetate = H2O + NAD(P)+ + homogentisate.
47095	2-hydroxycyclohexanone 2-monooxygenase activity	F	Catalysis of the reaction: 2-hydroxycyclohexan-1-one + NADPH + O(2) = 6-oxohexanoate + H(2)O + NADP(+).
47096	androst-4-ene-3,17-dione monooxygenase activity	F	Catalysis of the reaction: AH(2) + androst-4-ene-3,17-dione + O(2) = A + H(2)O + testololactone.
47097	phylloquinone monooxygenase (2,3-epoxidizing) activity	F	Catalysis of the reaction: AH(2) + O(2) + phylloquinone = 2,3-epoxyphylloquinone + A + H(2)O.
47098	Latia-luciferin monooxygenase (demethylating) activity	F	Catalysis of the reaction: 2 O2 + donor-H2 + Latia luciferin = light + H2O + acceptor + formate + CO2 + oxidized Latia luciferin.
47099	CDP-4-dehydro-6-deoxyglucose reductase activity	F	Catalysis of the reaction: H2O + NAD(P)+ + CDP-4-dehydro-3,6-dideoxy-D-glucose = NAD(P)H + CDP-4-dehydro-6-deoxy-D-glucose.
47100	glyceraldehyde-3-phosphate dehydrogenase (NADP+) (phosphorylating) activity	F	Catalysis of the reaction: phosphate + NADP+ + glyceraldehyde-3-phosphate = NADPH + 3-phospho-D-glyceroyl-phosphate.
47101	2-oxoisovalerate dehydrogenase (acylating) activity	F	Catalysis of the reaction: NAD+ + CoA + 2-keto-isovalerate = NADH + CO2 + isobutyryl-CoA.
47102	aminomuconate-semialdehyde dehydrogenase activity	F	Catalysis of the reaction: H2O + NAD+ + 2-aminomuconate semialdehyde = NADH + 2-amino-muconate.
47103	3-alpha,7-alpha,12-alpha-trihydroxycholestan-26-al 26-oxidoreductase activity	F	Catalysis of the reaction: H2O + NAD+ + 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestan-26-al = NADH + 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestanate.
47104	hexadecanal dehydrogenase (acylating) activity	F	Catalysis of the reaction: CoA + NAD(+) + palmitaldehyde = H(+) + NADH + palmitoyl-CoA.
47105	4-trimethylammoniobutyraldehyde dehydrogenase activity	F	Catalysis of the reaction: NAD+ + 4-trimethylammoniobutanal = NADH + 4-trimethylammoniobutanoate.
47106	4-hydroxyphenylacetaldehyde dehydrogenase activity	F	Catalysis of the reaction: NAD+ + (4-hydroxyphenyl)acetaldehyde + H2O = NADH + 4-hydroxyphenylacetate.
47107	gamma-guanidinobutyraldehyde dehydrogenase activity	F	Catalysis of the reaction: 4-guanidinobutanal + H(2)O + NAD(+) = 4-guanidinobutanoate + 2 H(+) + NADH.
47108	(R)-3-hydroxyacid-ester dehydrogenase activity	F	Catalysis of the reaction: ethyl (R)-3-hydroxyhexanoate + NADP(+) = ethyl 3-oxohexanoate + H(+) + NADPH.
47109	(S)-3-hydroxyacid-ester dehydrogenase activity	F	Catalysis of the reaction: ethyl (S)-3-hydroxyhexanoate + NADP(+) = ethyl 3-oxohexanoate + H(+) + NADPH.
47110	phenylglyoxylate dehydrogenase (acylating) activity	F	Catalysis of the reaction: CoA + NAD(+) + phenylglyoxylate = benzoyl-CoA + CO(2) + NADH.
47111	formate dehydrogenase (cytochrome-c-553) activity	F	Catalysis of the reaction: ferricytochrome C-553 + formate = ferrocytochrome C-553 + CO2.
47112	pyruvate oxidase activity	F	Catalysis of the reaction: H(+) + O(2) + phosphate + pyruvate = acetyl phosphate + CO(2) + H(2)O(2).
47113	aldehyde dehydrogenase (quinone) activity	F	Catalysis of the reaction: an aldehyde + a quinone + H2O = a carboxylate + a quinol.
47114	kynurenate-7,8-dihydrodiol dehydrogenase activity	F	Catalysis of the reaction: 7,8-dihydro-7,8-dihydroxykynurenate + NAD(+) = 7,8-dihydroxykynurenate + H(+) + NADH.
47115	trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity	F	Catalysis of the reaction: NADP+ + trans-1,2-dihydrobenzene-1,2-diol = NADPH + catechol.
47116	1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase activity	F	Catalysis of the reaction: NAD+ + 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate = NADH + CO2 + catechol.
47117	enoyl-[acyl-carrier-protein] reductase (NADPH, A-specific) activity	F	Catalysis of the reaction: acyl-[acyl-carrier protein] + NADP+ = trans-D2-enoyl-[acyl-carrier protein] + NADPH + H+.
47118	2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate reductase activity	F	Catalysis of the reaction: 2,6-dioxo-6-phenylhexanoate + NADP(+) = 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate + H(+) + NADPH.
47119	2-methyl-branched-chain-enoyl-CoA reductase activity	F	Catalysis of the reaction: 2-methylbutanoyl-CoA + NAD(+) = 2-methylbut-2-enoyl-CoA + H(+) + NADH.
47120	(3S,4R)-3,4-dihydroxycyclohexa-1,5-diene-1,4-dicarboxylate dehydrogenase activity	F	Catalysis of the reaction: (3S,4R)-3,4-dihydroxycyclohexa-1,5-diene-1,4-dicarboxylate + NAD(+) = 3,4-dihydroxybenzoate + CO(2) + NADH.
47121	isoquinoline 1-oxidoreductase activity	F	Catalysis of the reaction: A + H(2)O + isoquinoline = AH(2) + isoquinolin-1(2H)-one.
47122	quinaldate 4-oxidoreductase activity	F	Catalysis of the reaction: A + H(2)O + quinaldate = AH(2) + kynurenate.
47123	quinoline-4-carboxylate 2-oxidoreductase activity	F	Catalysis of the reaction: A + H(2)O + quinoline-4-carboxylate = 2-oxo-1,2-dihydroquinoline-4-carboxylate + AH(2).
47124	L-erythro-3,5-diaminohexanoate dehydrogenase activity	F	Catalysis of the reaction: (3S,5S)-3,5-diaminohexanoate + H(2)O + NAD(+) = (S)-5-amino-3-oxo-hexanoate + H(+) + NADH + NH(4)(+).
47125	delta1-piperideine-2-carboxylate reductase activity	F	Catalysis of the reaction: NADP+ + L-pipecolate = NADPH + delta1-piperideine-2-carboxylate.
47126	N5-(carboxyethyl)ornithine synthase activity	F	Catalysis of the reaction: N(5)-[1(S)-1-carboxyethyl]-L-ornithine + H(2)O + NADP(+) = L-ornithine + H(+) + NADPH + pyruvate.
47127	thiomorpholine-carboxylate dehydrogenase activity	F	Catalysis of the reaction: NAD(P)+ + thiomorpholine-3-carboxylate = NAD(P)H + 3,4-dehydro-1,4-thiomorpholine-3-carboxylate.
47128	1,2-dehydroreticulinium reductase (NADPH) activity	F	Catalysis of the reaction: (R)-reticuline + NADP(+) = 1,2-dehydroreticuline + H(+) + NADPH.
47129	opine dehydrogenase activity	F	Catalysis of the reaction: (2S)-2-[(R)-1-carboxyethylamino]pentanoate + H(2)O + NAD(+) = L-2-aminopentanoate + H(+) + NADH + pyruvate.
47130	saccharopine dehydrogenase (NADP+, L-lysine-forming) activity	F	Catalysis of the reaction: L-saccharopine + H(2)O + NADP(+) = 2-oxoglutarate + L-lysine + H(+) + NADPH.
47131	saccharopine dehydrogenase (NAD+, L-glutamate-forming) activity	F	Catalysis of the reaction: L-saccharopine + H(2)O + NAD(+) = L-glutamate + allysine + H(+) + NADH.
47132	dihydrobenzophenanthridine oxidase activity	F	Catalysis of the reaction: O2 + dihydrosanguinarine = H2O2 + sanguinarine.
47133	dimethylamine dehydrogenase activity	F	Catalysis of the reaction: electron-transferring flavoprotein + H2O + dimethylamine = reduced electron-transferring flavoprotein + formaldehyde + methylamine.
47134	protein-disulfide reductase activity	F	Catalysis of the reaction: protein-dithiol + NAD(P)+ = protein-disulfide + NAD(P)H + H+.
47135	bis-gamma-glutamylcystine reductase activity	F	Catalysis of the reaction: 2 L-gamma-glutamyl-L-cysteine + NADP(+) = bis-gamma-glutamylcystine + H(+) + NADPH.
47136	4-(dimethylamino)phenylazoxybenzene reductase activity	F	Catalysis of the reaction: 4-(dimethylamino)azobenzene + H(2)O + NADP(+) = 4-(dimethylamino)phenylazoxybenzene + H(+) + NADPH.
47137	N-hydroxy-2-acetamidofluorene reductase activity	F	Catalysis of the reaction: 2-acetamidofluorene + NAD(P)+ + H2O = N-hydroxy-2-acetamidofluorene + NAD(P)H + H+.
47138	aquacobalamin reductase activity	F	Catalysis of the reaction: 2 cob(II)alamin + NAD+ = 2 aquacob(III)alamin + NADH + H+.
47139	glutathione-homocystine transhydrogenase activity	F	Catalysis of the reaction: homocystine + 2 reduced glutathione = oxidized glutathione + 2 homocysteine.
47140	glutathione-CoA-glutathione transhydrogenase activity	F	Catalysis of the reaction: oxidized glutathione + CoA = reduced glutathione + CoA-glutathione.
47141	glutathione-cystine transhydrogenase activity	F	Catalysis of the reaction: cystine + 2 reduced glutathione = oxidized glutathione + 2 L-cysteine.
47142	enzyme-thiol transhydrogenase (glutathione-disulfide) activity	F	Catalysis of the reaction: oxidized glutathione + [xanthine dehydrogenase] = reduced glutathione + xanthine-oxidase.
47143	chlorate reductase activity	F	Catalysis of the reaction: AH(2) + chlorate = A + chlorite + H(2)O + H(+).
47144	2-acylglycerol-3-phosphate O-acyltransferase activity	F	Catalysis of the reaction: 2-acyl-sn-glycerol 3-phosphate + acyl-CoA = L-phosphatidate + CoA.
47145	demethylsterigmatocystin 6-O-methyltransferase activity	F	Catalysis of the reaction: 6-demethylsterigmatocystin + S-adenosyl-L-methionine = sterigmatocystin + S-adenosyl-homocysteine.
47146	sterigmatocystin 7-O-methyltransferase activity	F	Catalysis of the reaction: sterigmatocystin + S-adenosyl-L-methionine = 7-O-methylsterigmatocystin + S-adenosyl-homocysteine.
47147	trimethylsulfonium-tetrahydrofolate N-methyltransferase activity	F	Catalysis of the reaction: (6S)-5,6,7,8-tetrahydrofolate + trimethylsulfonium = (6S)-5-methyl-5,6,7,8-tetrahydrofolate + dimethyl sulfide + H(+).
47148	methylamine-glutamate N-methyltransferase activity	F	Catalysis of the reaction: L-glutamate + methylammonium = N-methyl-L-glutamate + NH(4)(+).
47149	thetin-homocysteine S-methyltransferase activity	F	Catalysis of the reaction: L-homocysteine + dimethylsulfonioacetate = (methylthio)acetate + L-methionine + H(+).
47150	betaine-homocysteine S-methyltransferase activity	F	Catalysis of the reaction: L-homocysteine + betaine = N,N-dimethylglycine + L-methionine.
47151	methylenetetrahydrofolate-tRNA-(uracil-5-)-methyltransferase (FADH2-oxidizing) activity	F	Catalysis of the reaction: 5,10-methylenetetrahydrofolate + tRNA containing uridine at position 54 + FADH + H+ = tetrahydrofolate + tRNA containing ribothymidine at position 54 + FAD+.
47152	methanol-5-hydroxybenzimidazolylcobamide Co-methyltransferase activity	F	Catalysis of the reaction: 5-hydroxybenzimidazolylcobamide + methanol = H2O + Co-methyl-Co-5-hydroxybenzimidazolylcob(I)amide.
47153	deoxycytidylate 5-hydroxymethyltransferase activity	F	Catalysis of the reaction: 5,10-methylenetetrahydrofolate + dCMP + H(2)O = (6S)-5,6,7,8-tetrahydrofolate + 5-hydroxymethyldeoxycytidylate.
47154	methylmalonyl-CoA carboxytransferase activity	F	Catalysis of the reaction: pyruvate + D-methylmalonyl-CoA = oxaloacetic acid + propionyl-CoA.
47155	3-hydroxymethylcephem carbamoyltransferase activity	F	Catalysis of the reaction: a 3-hydroxymethylceph-3-em-4-carboxylate + carbamoyl-phosphate = phosphate + a 3-carbamoyloxymethylcephem.
47156	acetoin-ribose-5-phosphate transaldolase activity	F	Catalysis of the reaction: D-ribose 5-phosphate + acetoin = 1-deoxy-D-altro-heptulose 7-phosphate + acetaldehyde.
47157	myelin-proteolipid O-palmitoyltransferase activity	F	Catalysis of the reaction: [myelin proteolipid] + palmityl-CoA = [myelin proteolipid] O-palmitoylprotein + CoA.
47158	sinapoylglucose-sinapoylglucose O-sinapoyltransferase activity	F	Catalysis of the reaction: 2 1-O-sinapoyl-beta-D-glucose = 1,2-di-O-sinapoyl-beta-D-glucose + D-glucose.
47159	1-alkenylglycerophosphocholine O-acyltransferase activity	F	Catalysis of the reaction: 1-alkenylglycerophosphocholine + acyl-CoA = 1-alkenyl-2-acylglycerophosphocholine + CoA.
47160	alkylglycerophosphate 2-O-acetyltransferase activity	F	Catalysis of the reaction: 1-alkyl-sn-glycerol 3-phosphate + acetyl-CoA = 1-alkyl-2-acetyl-sn-glycerol 3-phosphate + CoA.
47161	tartronate O-hydroxycinnamoyltransferase activity	F	Catalysis of the reaction: hydroxymalonate + sinapoyl-CoA = CoA + sinapoyltartronate.
47162	17-O-deacetylvindoline O-acetyltransferase activity	F	Catalysis of the reaction: (1R,9R,10S,11R,12R,19R)-12-ethyl-10,11-dihydroxy-5-methoxy-10-(methoxycarbonyl)-8-methyl-8,16-diazapentacyclo[10.6.1.0^{1,9}.0^{2,7}.0^{16,19}]nonadeca-2(7),3,5,13-tetraen-16-ium + acetyl-CoA = (1R,9R,10S,11R,12R,19R)-11-(acetyloxy)-12-ethyl-10-hydroxy-5-methoxy-10-(methoxycarbonyl)-8-methyl-8,16-diazapentacyclo[10.6.1.0^{1,9}.0^{2,7}.0^{16,19}]nonadeca-2(7),3,5,13-tetraen-16-ium + CoA.
47163	3,4-dichloroaniline N-malonyltransferase activity	F	Catalysis of the reaction: 3,4-dichloroaniline + malonyl-CoA = N-(3,4-dichlorophenyl)malonamate + CoA.
47164	isoflavone-7-O-beta-glucoside 6''-O-malonyltransferase activity	F	Catalysis of the reaction: biochanin-A + malonyl-CoA = 6'-malonyl-biochanin A + CoA.
47165	flavonol-3-O-beta-glucoside O-malonyltransferase activity	F	Catalysis of the reaction: flavonol 3-O-beta-D-glucoside + malonyl-CoA = malonyl-flavonol 3-O-beta-D-glucoside + CoA.
47166	1-alkenylglycerophosphoethanolamine O-acyltransferase activity	F	Catalysis of the reaction: 1-alkenylglycerophosphoethanolamine + acyl-CoA = 1-alkenyl-2-acyl-glycerophosphoethanolamine + CoA.
47167	1-alkyl-2-acetylglycerol O-acyltransferase activity	F	Catalysis of the reaction: 1-O-alkyl-2-acetyl-sn-glycerol + acyl-CoA = 1-O-alkyl-2-acetyl-3-acyl-sn-glycerol + CoA.
47168	isocitrate O-dihydroxycinnamoyltransferase activity	F	Catalysis of the reaction: caffeoyl-CoA + isocitrate = 2-caffeoylisocitrate + CoA.
47169	galactarate O-hydroxycinnamoyltransferase activity	F	Catalysis of the reaction: feruloyl-CoA + galactarate = 2-(E)-O-feruloyl-D-galactarate + CoA.
47170	glucarate O-hydroxycinnamoyltransferase activity	F	Catalysis of the reaction: D-glucarate + sinapoyl-CoA = 2-O-sinapoyl-D-glucarate + CoA.
47171	glucarolactone O-hydroxycinnamoyltransferase activity	F	Catalysis of the reaction: glucarolactone + sinapoyl-CoA = O-sinapoylglucarolactone + CoA.
47172	shikimate O-hydroxycinnamoyltransferase activity	F	Catalysis of the reaction: shikimate + coumaroyl-CoA = 4-coumaroylshikimate + CoA.
47173	phosphatidylcholine-retinol O-acyltransferase activity	F	Catalysis of the reaction: retinol-[cellular-retinol-binding-protein] + phosphatidylcholine = retinyl-ester-[cellular-retinol-binding-protein] + 2-acylglycerophosphocholine.
47174	putrescine N-hydroxycinnamoyltransferase activity	F	Catalysis of the reaction: caffeoyl-CoA + putrescine = N-caffeoylputrescine + CoA + H(+).
47175	galactosylacylglycerol O-acyltransferase activity	F	Catalysis of the reaction: sn-3-D-galactosyl-sn-2-acylglycerol + acyl-[acyl-carrier protein] = D-galactosyldiacylglycerol + [acyl-carrier protein].
47176	beta-glucogallin-tetrakisgalloylglucose O-galloyltransferase activity	F	Catalysis of the reaction: 1,2,3,6-tetrakis-O-galloyl-beta-D-glucose + 1-O-galloyl-beta-D-glucose = 1,2,3,4,6-pentakis-O-galloyl-beta-D-glucose + D-glucose.
47177	glycerophospholipid arachidonoyl-transferase (CoA-independent) activity	F	Catalysis of the reaction: 1-alkyl-2-lyso-sn-glycero-3-phosphoethanolamine + 1-alkyl-2-arachidonyl-sn-glycero-3-phosphocholine = 1-alkyl-2-lyso-sn-glycero-3-phosphocholine + 1-alkyl-2-arachidonyl-sn-glycero-3-phosphoethanolamine.
47178	glycerophospholipid acyltransferase (CoA-dependent) activity	F	Catalysis of the reaction: 1-radyl-2-lyso-sn-glycero-3-phosphoethanolamine + 1-radyl-2-acyl-sn-glycero-3-phosphocholine = 1-radyl-2-lyso-sn-glycero-3-phosphocholine + 1-radyl-2-acyl-sn-glycero-3-phosphoethanolamine.
47179	platelet-activating factor acetyltransferase activity	F	Catalysis of the reaction: 1-radyl-2-acyl-sn-glycero-3-phospholipid + 1-alkyl-2-acetyl-sn-glycero-3-phosphocholine = 1-alkyl-2-lyso-sn-glycero-3-phosphocholine + 1-radyl-2-acetyl-sn-glycero-3-phospholipid.
47180	salutaridinol 7-O-acetyltransferase activity	F	Catalysis of the reaction: (7S)-salutaridinol + acetyl-CoA = (7S)-O-acetylsalutaridinol + CoA.
47181	benzophenone synthase activity	F	Catalysis of the reaction: 3-hydroxybenzoyl-CoA + 3 malonyl-CoA = 3 CO2 + 2,3',4,6-tetrahydroxybenzophenone + 4 coenzyme A.
47182	alcohol O-cinnamoyltransferase activity	F	Catalysis of the reaction: an alcohol + 1-O-trans-cinnamoyl-beta-D-glucopyranose = beta-D-glucose + alkyl cinnamate.
47183	anthocyanin 5-aromatic acyltransferase activity	F	Catalysis of the reaction: anthocyanidin-3,5-diglucoside + hydroxycinnamoyl-CoA = anthocyanidin 3-glucoside-5-hydroxycinnamoylglucoside + CoA.
47184	1-acylglycerophosphocholine O-acyltransferase activity	F	Catalysis of the reaction: 1-acyl-sn-glycero-3-phosphocholine + acyl-CoA = phosphatidylcholine + CoA.
47185	N-acetylneuraminate 4-O-acetyltransferase activity	F	Catalysis of the reaction: N-acetylneuraminate + acetyl-CoA = N-acetyl-4-O-acetylneuraminate + CoA.
47186	N-acetylneuraminate 7-O(or 9-O)-acetyltransferase activity	F	Catalysis of the reaction: N-acetylneuraminate + acetyl-CoA = N-acetyl-7-O(or 9-O)-acetylneuraminate + CoA.
47187	deacetyl-[citrate-(pro-3S)-lyase] S-acetyltransferase activity	F	Catalysis of the reaction: deacetyl-[citrate-oxaloacetate-lyase ((pro-3S)-CH(2)COO(-)-acetate)] + S-acetylphosphopantetheine = [citrate oxaloacetate-lyase ((pro-3S)-CH(2)COO(-)-acetate)] + pantetheine 4'-phosphate.
47188	aromatic-hydroxylamine O-acetyltransferase activity	F	Catalysis of the reaction: N-hydroxy-4-aminobiphenyl + N-hydroxy-4-acetylaminonbiphenyl = N-acetoxy-4-aminobiphenyl + N-hydroxy-4-aminobiphenyl.
47189	2,3-diaminopropionate N-oxalyltransferase activity	F	Catalysis of the reaction: 3-amino-L-alanine + oxalyl-CoA = N(3)-oxalyl-L-2,3-diaminopropanoate + CoA.
47190	2-acylglycerophosphocholine O-acyltransferase activity	F	Catalysis of the reaction: 2-acyl-sn-glycero-3-phosphocholine + acyl-CoA = 1,2-diacyl-sn-glycero-3-phosphocholine + CoA.
47191	1-alkylglycerophosphocholine O-acyltransferase activity	F	Catalysis of the reaction: 1-alkyl-sn-glycero-3-phosphocholine + acyl-CoA = 1-alkyl-2-acyl-sn-glycero-3-phosphocholine + CoA.
47192	1-alkylglycerophosphocholine O-acetyltransferase activity	F	Catalysis of the reaction: 1-alkyl-sn-glycero-3-phosphocholine + acetyl-CoA = 1-alkyl-2-acetyl-sn-glycero-3-phosphocholine + CoA.
47194	indoleacetylglucose-inositol O-acyltransferase activity	F	Catalysis of the reaction: 1-O-(indol-3-ylacetyl)-beta-D-glucose + myo-inositol = 1L-1-O-(indol-3-yl)acetyl-myo-inositol + D-glucose.
47195	diacylglycerol-sterol O-acyltransferase activity	F	Catalysis of the reaction: sterol + 1,2-diacylglycerol = sterol ester + acylglycerol.
47196	long-chain-alcohol O-fatty-acyltransferase activity	F	Catalysis of the reaction: a long-chain-alcohol + acyl-CoA = a long-chain ester + CoA.
47197	triglyceride-sterol O-acyltransferase activity	F	Catalysis of the reaction: a 3-beta-hydroxysterol + triacylglycerol = a 3-beta-hydroxysterol ester + 1,2-diacylglycerol.
47198	cysteine-S-conjugate N-acetyltransferase activity	F	Catalysis of the reaction: S-substituted L-cysteine + acetyl-CoA = S-substituted N-acetyl-L-cysteine + CoA + H(+).
47199	phosphatidylcholine-dolichol O-acyltransferase activity	F	Catalysis of the reaction: 1,2-diacyl-sn-glycero-3-phosphocholine + dolichol = 1-acyl-sn-glycero-3-phosphocholine + acyldolichol.
47200	tetrahydrodipicolinate N-acetyltransferase activity	F	Catalysis of the reaction: (S)-2,3,4,5-tetrahydrodipicolinate + acetyl-CoA + H(2)O = L-2-acetamido-6-oxopimelate + CoA.
47201	beta-glucogallin O-galloyltransferase activity	F	Catalysis of the reaction: 2 1-O-galloyl-beta-D-glucose = 1,6-bis-O-galloyl-beta-D-glucose + D-glucose.
47202	sinapoylglucose-choline O-sinapoyltransferase activity	F	Catalysis of the reaction: 1-O-sinapoyl-beta-D-glucose + choline = O-sinapoylcholine + D-glucose.
47203	13-hydroxylupinine O-tigloyltransferase activity	F	Catalysis of the reaction: 13-hydroxylupanine + 2-methylcrotonoyl-CoA = 13-(2-methylcrotonoyloxy)lupanine + CoA.
47204	chlorogenate-glucarate O-hydroxycinnamoyltransferase activity	F	Catalysis of the reaction: D-glucarate + chlorogenate = (-)-quinate + 2-O-caffeoylglucarate.
47205	quinate O-hydroxycinnamoyltransferase activity	F	Catalysis of the reaction: feruloyl-CoA + quinate = O-feruloylquinate + CoA.
47206	UDP-N-acetylmuramoylpentapeptide-lysine N6-alanyltransferase activity	F	Catalysis of the reaction: UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-D-alanyl-D-alanine + L-alanyl-tRNA = UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-N6-(L-alanyl)-L-lysyl-D-alanyl-D-alanine + tRNA.
47207	1,2-beta-fructan 1F-fructosyltransferase activity	F	Catalysis of the reaction: [(1->2)-beta-D-fructosyl](n) + [(1->2)-beta-D-fructosyl](m) = [(1->2)-beta-D-fructosyl](n+1) + [(1->2)-beta-D-fructosyl](m-1).
47208	o-dihydroxycoumarin 7-O-glucosyltransferase activity	F	Catalysis of the reaction: 7,8-dihydroxycoumarin + UDP-D-glucose = daphnin + H(+) + UDP.
47209	coniferyl-alcohol glucosyltransferase activity	F	Catalysis of the reaction: coniferyl alcohol + UDP-D-glucose = coniferin + UDP.
47211	alpha-1,4-glucan-protein synthase (ADP-forming) activity	F	Catalysis of the reaction: ADP-D-glucose + protein = alpha-D-glucosyl-protein + ADP.
47212	2-coumarate O-beta-glucosyltransferase activity	F	Catalysis of the reaction: trans-2-coumarate + UDP-D-glucose = trans-beta-D-glucosyl-2-hydroxycinnamate + H(+) + UDP.
47213	anthocyanidin 3-O-glucosyltransferase activity	F	Catalysis of the reaction: anthocyanidin + UDP-D-glucose = anthocyanidin-3-O-D-glucoside + UDP.
47214	cyanidin-3-rhamnosylglucoside 5-O-glucosyltransferase activity	F	Catalysis of the reaction: cyanidin-3-O-D-rhamnosyl-(1,6)-D-glucoside + UDP-D-glucose = cyanidin-3-O-[D-rhamnosyl-(1,6)-D-glucoside]-5-O-D-glucoside + UDP.
47215	indole-3-acetate beta-glucosyltransferase activity	F	Catalysis of the reaction: (indol-3-yl)acetate + UDP-D-glucose = 1-O-(indol-3-ylacetyl)-beta-D-glucose + UDP.
47216	inositol 3-alpha-galactosyltransferase activity	F	Catalysis of the reaction: myo-inositol + UDP-galactose = O-alpha-D-galactosyl-(1,3)-1D-myo-inositol + UDP.
47217	sucrose-1,6-alpha-glucan 3(6)-alpha-glucosyltransferase activity	F	Catalysis of the reaction: sucrose + 1,6-alpha-D-glucosyl(n) = 1,6-alpha-D-glucosyl(n+1) + fructose.
47218	hydroxycinnamate 4-beta-glucosyltransferase activity	F	Catalysis of the reaction: 4-coumarate + UDP-D-glucose = 4-O-beta-D-glucosyl-4-hydroxycinnamate + UDP.
47219	monoterpenol beta-glucosyltransferase activity	F	Catalysis of the reaction: (-)-menthol + UDP-D-glucose = (-)-menthyl beta-D-glucoside + H(+) + UDP.
47220	galactosylxylosylprotein 3-beta-galactosyltransferase activity	F	Catalysis of the reaction: 4-beta-D-galactosyl-O-beta-D-xylosylprotein + UDP-galactose = 3-beta-D-galactosyl-4-beta-D-galactosyl-O-beta-D-xylosylprotein + UDP.
47221	sn-glycerol-3-phosphate 2-alpha-galactosyltransferase activity	F	Catalysis of the reaction: sn-glycerol 3-phosphate + UDP-D-galactose = 2-(alpha-D-galactosyl)-sn-glycerol 3-phosphate + H(+) + UDP.
47222	mannotetraose 2-alpha-N-acetylglucosaminyltransferase activity	F	Catalysis of the reaction: 1,3-alpha-D-mannosyl-1,2-alpha-D-mannosyl-1,2-alpha-D-mannosyl-D-mannose + UDP-N-acetyl-D-glucosamine = 1,3-alpha-D-mannosyl-1,2-(N-acetyl-alpha-D-glucosaminyl-alpha-D-mannosyl)-1,2-alpha-D-mannosyl-D-mannose + UDP.
47223	beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity	F	Catalysis of the reaction: beta-D-galactosyl-1,3-(N-acetyl-D-glucosaminyl-1,6)-N-acetyl-D-galactosaminyl-R + UDP-N-acetyl-D-glucosamine = N-acetyl-beta-D-glucosaminyl-1,3-beta-D-galactosyl-1,3-(N-acetyl-beta-D-glucosaminyl-1,6)-N-acetyl-D-galactosaminyl-R + UDP.
47224	acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity	F	Catalysis of the reaction: N-acetyl-D-galactosalaminyl-R + UDP-N-acetyl-D-glucosamine = N-acetyl-beta-D-glucosaminyl-1,3-N-acetyl-D-galactosaminyl-R + UDP.
47225	acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity	F	Catalysis of the reaction: N-acetyl-beta-D-glucosaminyl-1,3-N-acetyl-D-galactosaminyl-R + UDP-N-acetyl-D-glucosamine = N-acetyl-beta-D-glucosaminyl-1,6-(N-acetyl-beta-D-glucosaminyl-1,3)-N-acetyl-D-galactosaminyl-R + UDP.
47227	indolylacetyl-myo-inositol galactosyltransferase activity	F	Catalysis of the reaction: 1L-1-O-(indol-3-yl)acetyl-myo-inositol + UDP-D-galactose = 5-O-(indol-3-ylacetyl)-myo-inositol D-galactoside + H(+) + UDP.
47228	1,2-diacylglycerol 3-glucosyltransferase activity	F	Catalysis of the reaction: 1,2-diacylglycerol + UDP-D-glucose = 3-D-glucosyl-1,2-diacylglycerol + UDP.
47229	13-hydroxydocosanoate 13-beta-glucosyltransferase activity	F	Catalysis of the reaction: 13-hydroxydocosanoate + UDP-D-glucose = 13-beta-D-glucosyloxydocosanoate + UDP.
47230	flavonol-3-O-glucoside L-rhamnosyltransferase activity	F	Catalysis of the reaction: flavonol 3-O-D-glucoside + UDP-L-rhamnose = flavonol 3-O-L-rhamnosylglucoside + UDP.
47231	pyridoxine 5'-O-beta-D-glucosyltransferase activity	F	Catalysis of the reaction: pyridoxine + UDP-D-glucose = 5'-O-beta-D-glucosylpyridoxine + H(+) + UDP.
47232	galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,6-N-acetylglucosaminyltransferase activity	F	Catalysis of the reaction: D-galactosyl-1,4-N-acetyl-beta-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-beta-D-glucosylceramide + UDP-N-acetyl-D-glucosamine = N-acetyl-D-glucosaminyl-1,6-beta-D-galactosyl-1,4-N-acetyl-beta-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-beta-D-glucosyceramide + UDP.
47233	N-acetylneuraminylgalactosylglucosylceramide beta-1,4-N-acetylgalactosaminyltransferase activity	F	Catalysis of the reaction: N-acetylneuraminyl-2,3-alpha-D-galactosyl-1,4-beta-D-glucosylceramide + UDP-N-acetylgalactosamine = N-acetyl-beta-D-galactosaminyl-1,4-(N-acetyl-alpha-neuraminyl-2,3)-beta-D-galactosyl-1,4-beta-D-glucosylceramide + UDP.
47234	raffinose-raffinose alpha-galactotransferase activity	F	Catalysis of the reaction: 2 raffinose = sucrose + 1F-alpha-D-galactosylraffinose.
47235	sucrose 6F-alpha-galactotransferase activity	F	Catalysis of the reaction: sucrose + UDP-galactose = 6F-alpha-D-galactosylsucrose + UDP.
47236	methyl-ONN-azoxymethanol beta-D-glucosyltransferase activity	F	Catalysis of the reaction: methylazoxymethanol + UDP-D-glucose = H+ + cycasin + UDP.
47237	glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity	F	Catalysis of the reaction: D-glucuronyl-1,3-beta-D-galactosylproteoglycan + UDP-N-acetylgalactosamine = N-acetyl-D-galactosaminyl-1,4-beta-D-glucuronyl-1,3-beta-D-galactosylproteoglycan + UDP.
47238	glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity	F	Catalysis of the reaction: D-glucuronyl-N-acetyl-1,3-beta-D-galactosaminylproteoglycan + UDP-N-acetylgalactosamine = N-acetyl-D-galactosaminyl-1,4-beta-D-glucuronyl-N-acetyl-1,3-beta-D-galactosaminylproteoglycan + UDP.
47239	hydroxymandelonitrile glucosyltransferase activity	F	Catalysis of the reaction: 4-hydroxymandelonitrile + UDP-D-glucose = H(+) + taxiphyllin + UDP.
47240	lactosylceramide beta-1,3-galactosyltransferase activity	F	Catalysis of the reaction: D-galactosyl-(1->4)-beta-D-glucosyl-R + UDP-D-galactose = D-galactosyl-(1->3)-beta-D-galactosyl-(1->4)-beta-D-glucosyl-R + H(+) + UDP.
47241	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity	F	Catalysis of the reaction: lipopolysaccharide + UDP-N-acetylmannosaminouronate = N-acetyl-beta-D-mannosaminouronosyl-1,4-lipopolysaccharide + UDP.
47242	hydroxyanthraquinone glucosyltransferase activity	F	Catalysis of the reaction: a hydroxyanthraquinone + UDP-D-glucose = a glucosyloxyanthraquinone + UDP.
47243	flavanone 7-O-beta-glucosyltransferase activity	F	Catalysis of the reaction: a flavanone + UDP-D-glucose = a flavanone 7-O-beta-D-glucoside + UDP.
47244	N-acetylglucosaminyldiphosphoundecaprenol N-acetyl-beta-D-mannosaminyltransferase activity	F	Catalysis of the reaction: N-acetyl-D-glucosaminyldiphosphoundecaprenol + UDP-N-acetyl-D-mannosamine = N-acetyl-beta-D-mannosaminyl-1,4-N-acetyl-D-glucosaminyldiphosphoundecaprenol + UDP.
47245	N-acetylglucosaminyldiphosphoundecaprenol glucosyltransferase activity	F	Catalysis of the reaction: N-acetyl-D-glucosaminyldiphosphoundecaprenol + UDP-D-glucose = beta-D-glucosyl-1,4-N-acetyl-D-glucosaminyldiphosphoundecaprenol + UDP.
47246	luteolin-7-O-glucuronide 7-O-glucuronosyltransferase activity	F	Catalysis of the reaction: luteolin 7-O-beta-D-glucosiduronate + UDP-alpha-D-glucuronate = H(+) + luteolin 7-O-[(beta-D-glucosiduronate)-(1->2)-(beta-D-glucosiduronate)] + UDP.
47247	luteolin-7-O-diglucuronide 4'-O-glucuronosyltransferase activity	F	Catalysis of the reaction: luteolin 7-O-[(beta-D-glucosiduronate)-(1->2)-(beta-D-glucosiduronate)] + UDP-alpha-D-glucuronate = H(+) + luteolin 7-O-[(beta-D-glucosiduronate)-(1->2)-(beta-D-glucosiduronate)] 4'-O-beta-D-glucosiduronate + UDP.
47248	nuatigenin 3-beta-glucosyltransferase activity	F	Catalysis of the reaction: nuatigenin + UDP-D-glucose = H(+) + nuatigenin 3-beta-D-glucopyranoside + UDP.
47249	sarsapogenin 3-beta-glucosyltransferase activity	F	Catalysis of the reaction: (25S)-5beta-spirostan-3beta-ol + UDP-D-glucose = (25S)-5beta-spirostan-3beta-yl beta-D-glucoside + H(+) + UDP.
47250	4-hydroxybenzoate 4-O-beta-D-glucosyltransferase activity	F	Catalysis of the reaction: 4-hydroxybenzoate + UDP-D-glucose = 4-(beta-D-glucosyloxy)benzoate + H(+) + UDP.
47251	thiohydroximate beta-D-glucosyltransferase activity	F	Catalysis of the reaction: phenylthioacetohydroximate + UDP-D-glucose = desulfoglucotropeolin + UDP.
47252	beta-mannosylphosphodecaprenol-mannooligosaccharide 6-mannosyltransferase activity	F	Catalysis of the reaction: (1->6)-alpha-D-mannosyloligosaccharide + beta-D-mannosylphosphodecaprenol = (1->6)-alpha-D-mannosyl-(1->6)-alpha-D-mannosyl-oligosaccharide + decaprenol phosphate.
47253	alpha-1,6-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity	F	Catalysis of the reaction: N-acetyl-beta-D-glucosaminyl-1,6-beta-D-(N-acetyl-B-glucosaminyl-1,2)-beta-D-mannosyl-R + UDP-N-acetyl-D-glucosamine = N-acetyl-beta-D-glucosaminyl-1,6-beta-D-(N-acetyl-D-glucosaminyl-1,2-beta)-(N-acetyl-D-glucosaminyl-1,4-beta)-D-mannosyl-R + UDP.
47254	2,4-dihydroxy-7-methoxy-2H-1,4-benzoxazin-3(4H)-one 2-D-glucosyltransferase activity	F	Catalysis of the reaction: 2,4-dihydroxy-7-methoxy-2H-1,4-benzoxazin-3(4H)-one + UDP-D-glucose = 2,4-dihydroxy-7-methoxy-2H-1,4-benzoxazin-3(4H)-one 2-D-glucoside + UDP.
47255	galactogen 6-beta-galactosyltransferase activity	F	Catalysis of the reaction: galactogen + UDP-galactose = 1,6-beta-D-galctosylgalactogen + UDP.
47256	lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity	F	Catalysis of the reaction: cytolipin-H + UDP-N-acetyl-D-glucosamine = N-acetyl-D-glucosaminyl-1,3-beta-D-galactosyl-1,4-beta-D-glucosylceramide + UDP.
47257	diglucosyl diacylglycerol synthase activity	F	Catalysis of the reaction: 1,2-diacyl-3-O-(alpha-D-glucopyranosyl)-sn-glycerol + UDP-D-glucose = UDP + 1,2-diacyl-3-O-(alpha-D-glucopyranosyl(1,2)-O-alpha-D-glucopyranosyl)-sn-glycerol.
47258	sphingosine beta-galactosyltransferase activity	F	Catalysis of the reaction: sphingosine + UDP-D-galactose = H(+) + psychosine + UDP.
47259	glucomannan 4-beta-mannosyltransferase activity	F	Catalysis of the reaction: glucomannan(n) + GDP-mannose = glucomannan(n+1) + GDP.
47260	alpha,alpha-trehalose-phosphate synthase (GDP-forming) activity	F	Catalysis of the reaction: GDP-D-glucose + glucose-6-phosphate = alpha,alpha-trehalose 6-phosphate + GDP.
47261	steroid N-acetylglucosaminyltransferase activity	F	Catalysis of the reaction: estradiol-17alpha 3-D-glucuronoside + UDP-N-acetyl-alpha-D-glucosamine = 17alpha-(N-acetyl-D-glucosaminyl)-estradiol 3-D-glucuronoside + H(+) + UDP.
47262	polygalacturonate 4-alpha-galacturonosyltransferase activity	F	Catalysis of the reaction: UDP-D-galacturonate + 1,4-alpha-D-galacturonosyl(n) = 1,4-alpha-D-galacturonosyl(n+1) + UDP.
47263	N-acylsphingosine galactosyltransferase activity	F	Catalysis of the reaction: ceramide + UDP-galactose = D-galactosylceramide + UDP.
47264	heteroglycan alpha-mannosyltransferase activity	F	Catalysis of the reaction: heteroglycan + GDP-mannose = alpha-D-mannosylheteroglycan + GDP.
47265	poly(glycerol-phosphate) alpha-glucosyltransferase activity	F	Catalysis of the reaction: poly(glycerol phosphate) + UDP-D-glucose = alpha-D-glucosylpoly(glycerol phosphate) + UDP.
47266	poly(ribitol-phosphate) beta-glucosyltransferase activity	F	Catalysis of the reaction: poly(ribitol phosphate) + UDP-D-glucose = beta-D-glucosylpoly(ribitol phosphate) + UDP.
47267	undecaprenyl-phosphate mannosyltransferase activity	F	Catalysis of the reaction: GDP-mannose + undecaprenyl phosphate = GDP + D-mannosyl-1-phosphoundecaprenol.
47268	galactinol-raffinose galactosyltransferase activity	F	Catalysis of the reaction: raffinose + 1-alpha-D-galactosyl-myo-inositol = stachyose + myo-inositol.
47269	poly(ribitol-phosphate) N-acetylglucosaminyltransferase activity	F	Catalysis of the reaction: poly(ribitol phosphate) + UDP-N-acetyl-D-glucosamine = N-acetyl-D-glucosaminyl-poly(ribitol phosphate) + UDP.
47270	lipopolysaccharide glucosyltransferase II activity	F	Catalysis of the reaction: lipopolysaccharide + UDP-D-glucose = D-glucosyl-lipopolysaccharide + UDP.
47271	glycosaminoglycan galactosyltransferase activity	F	Catalysis of the reaction: glycosaminoglycan + UDP-galactose = D-galactosylglycosaminoglycan + UDP.
47272	phosphopolyprenol glucosyltransferase activity	F	Catalysis of the reaction: polyprenyl phosphate + UDP-D-glucose = polyprenylphosphate-glucose + UDP.
47273	galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity	F	Catalysis of the reaction: UDP-N-acetyl-D-galactosamine + alpha-D-galactosyl-(1->4)-beta-D-galactosyl-(1->4)-beta-D-glucosylceramide = UDP + beta-N-acetyl-D-galactosaminyl-(1->3)-alpha-D-galactosyl-(1->4)-beta-D-galactosyl-(1->4)-beta-D-glucosylceramide.
47274	galactinol-sucrose galactosyltransferase activity	F	Catalysis of the reaction: sucrose + 1-alpha-D-galactosyl-myo-inositol = raffinose + myo-inositol.
47275	glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity	F	Catalysis of the reaction: N-acetyl-D-glucosaminyl-(1,3)-D-galactosyl-(1,4)-D-glucosylceramide + UDP-galactose = D-galactosyl-N-acetyl-D-glucosaminyl-(1,3)-D-galactosyl-(1,4)-D-glucosylceramide + UDP.
47276	N-acetyllactosaminide 3-alpha-galactosyltransferase activity	F	Catalysis of the reaction: beta-D-galactosyl-(1,4)-beta-N-acetyl-D-glucosaminyl-R + UDP-galactose = alpha-D-galactosyl-(1,3)-beta-D-galactosyl-(1,4)-beta-N-acetyl-D-glucosaminyl-R + UDP.
47277	globoside alpha-N-acetylgalactosaminyltransferase activity	F	Catalysis of the reaction: N-acetyl-D-galactosaminyl-(1,3)-D-galactosyl-(1,4)-D-galactosyl-(1,4)-D-glucosylceramide + UDP-N-acetylgalactosamine = N-acetyl-D-galactosaminyl-N-acetyl-D-galactosaminyl-(1,3)-D-galactosyl-(1,4)-D-galactosyl-(1,4)-D-glucosylceramide + UDP.
47278	bilirubin-glucuronoside glucuronosyltransferase activity	F	Catalysis of the reaction: 2 bilirubin-glucuronoside = bilirubin + bilirubin-bisglucuronoside.
47279	sn-glycerol-3-phosphate 1-galactosyltransferase activity	F	Catalysis of the reaction: sn-glycerol 3-phosphate + UDP-D-galactose = 1-O-alpha-D-galactosyl-sn-glycerol 3-phosphate + H(+) + UDP.
47280	nicotinamide phosphoribosyltransferase activity	F	Catalysis of the reaction: diphosphate + nicotinamide mononucleotide = 5-phospho-alpha-D-ribose 1-diphosphate + H(+) + nicotinamide.
47281	dioxotetrahydropyrimidine phosphoribosyltransferase activity	F	Catalysis of the reaction: pyrophosphate + a 2,4-dioxotetrahydropyrimidine D-ribonucleotide = PRPP + a 2,4-dioxotetrahydropyrimidine.
47282	dTDP-dihydrostreptose-streptidine-6-phosphate dihydrostreptosyltransferase activity	F	Catalysis of the reaction: dTDP-L-dihydrostreptose + streptidine 6-phosphate = O-(1->4)-alpha-L-dihydrostreptosyl-streptidine 6-phosphate + dTDP + H(+).
47283	dolichyl-phosphate D-xylosyltransferase activity	F	Catalysis of the reaction: dolichol-phosphate + UDP-D-xylose = dolichyl D-xylosyl phosphate + UDP.
47284	dolichyl-xylosyl-phosphate-protein xylosyltransferase activity	F	Catalysis of the reaction: dolichyl D-xylosyl phosphate + protein = dolichol-phosphate + D-xylosylprotein.
47285	flavonol-3-O-glycoside xylosyltransferase activity	F	Catalysis of the reaction: flavonol 3-O-glycoside + UDP-D-xylose = flavonol 3-O-D-xylosylglycoside + UDP.
47286	NAD+-diphthamide ADP-ribosyltransferase activity	F	Catalysis of the reaction: peptide diphthamide + NAD+ = peptide N-(ADP-D-ribosyl)diphthamide + niacinamide.
47287	lactosylceramide alpha-2,6-N-sialyltransferase activity	F	Catalysis of the reaction: cytolipin-H + CMP-N-acetylneuraminate = alpha-N-acetylneuraminyl-2,6-beta-galactosyl-1,4-beta-D-glucosylceramide + CMP.
47288	monosialoganglioside sialyltransferase activity	F	Catalysis of the reaction: D-galactosyl-N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide + CMP-N-acetylneuraminate = N-acetylneuraminyl-D-galactosyl-N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosylceramide + CMP.
47289	galactosyldiacylglycerol alpha-2,3-sialyltransferase activity	F	Catalysis of the reaction: 1,2-diacyl-3-beta-D-galactosyl-sn-glycerol + CMP-N-acetyl-beta-neuraminate = 1,2-diacyl-3-[3-(alpha-D-N-acetylneuraminyl)-beta-D-galactosyl]-sn-glycerol + CMP + H(+).
47290	(alpha-N-acetylneuraminyl-2,3-beta-galactosyl-1,3)-N-acetyl-galactosaminide 6-alpha-sialyltransferase activity	F	Catalysis of the reaction: alpha-N-acetylneuraminyl-(2->3)-beta-D-galactosyl-(1->3)-N-acetyl-D-galactosaminyl-R + CMP-N-acetyl-beta-neuraminate = alpha-N-acetylneuraminyl-(2->3)-beta-D-galactosyl-(1->3)-[N-acetyl-alpha-neuraminyl-(2->6)]-N-acetyl-D-galactosaminyl-R + CMP.
47291	lactosylceramide alpha-2,3-sialyltransferase activity	F	Catalysis of the reaction: cytolipin-H + CMP-N-acetylneuraminate = alpha-N-acetylneuraminyl-2,3-beta-D-galactosyl-1,4-beta-D-glucosylceramide + CMP. Alpha-N-acetylneuraminyl-2,3-beta-D-galactosyl-1,4-beta-D-glucosylceramide is also known as GM3.
47292	trihydroxypterocarpan dimethylallyltransferase activity	F	Catalysis of the reaction: (6AS,11AS)-3,6A,9-trihydroxypterocarpan + dimethylallyl-pyrophosphate = glyceollin + diphosphate.
47293	4-hydroxybenzoate nonaprenyltransferase activity	F	Catalysis of the reaction: p-hydroxybenzoate + solanesyl pyrophosphate = nonaprenyl-4-hydroxybenzoate + diphosphate.
47294	phosphoglycerol geranylgeranyltransferase activity	F	Catalysis of the reaction: sn-glycerol 1-phosphate + all-trans-geranylgeranyl diphosphate = sn-3-O-(geranylgeranyl)glycerol 1-phosphate + diphosphate.
47295	geranylgeranylglycerol-phosphate geranylgeranyltransferase activity	F	Catalysis of the reaction: sn-3-O-(geranylgeranyl)glycerol 1-phosphate + all-trans-geranylgeranyl diphosphate = 2,3-di-O-(geranylgeranyl)glycerol 1-phosphate + diphosphate.
47296	homospermidine synthase activity	F	Catalysis of the reaction: 2 putrescine = NH3 + sym-homospermidine.
47297	asparagine-oxo-acid transaminase activity	F	Catalysis of the reaction: a 2-oxo acid + L-asparagine = an amino acid + 2-oxosuccinamate.
47298	(S)-3-amino-2-methylpropionate transaminase activity	F	Catalysis of the reaction: (S)-3-amino-2-methylpropanoate + 2-oxoglutarate = 2-methyl-3-oxopropanoate + L-glutamate.
47299	tryptophan-phenylpyruvate transaminase activity	F	Catalysis of the reaction: keto-phenylpyruvate + L-tryptophan = 3-(indol-3-yl)pyruvate + L-phenylalanine.
47300	pyridoxamine-pyruvate transaminase activity	F	Catalysis of the reaction: pyridoxamine + pyruvate = L-alanine + pyridoxal.
47301	valine-3-methyl-2-oxovalerate transaminase activity	F	Catalysis of the reaction: (S)-3-methyl-2-oxopentanoate + L-valine = 3-methyl-2-oxobutanoate + L-isoleucine.
47302	UDP-2-acetamido-4-amino-2,4,6-trideoxyglucose transaminase activity	F	Catalysis of the reaction: 2-oxoglutarate + UDP-2-acetamido-4-amino-2,4,6-trideoxy-D-glucose = L-glutamate + UDP-2-acetamido-4-dehydro-2,6-dideoxy-beta-D-glucose.
47303	glycine-oxaloacetate transaminase activity	F	Catalysis of the reaction: glycine + oxaloacetate = L-aspartate + glyoxylate.
47304	2-aminoethylphosphonate-pyruvate transaminase activity	F	Catalysis of the reaction: (2-aminoethyl)phosphonate + pyruvate = L-alanine + phosphonoacetaldehyde.
47305	(R)-3-amino-2-methylpropionate-pyruvate transaminase activity	F	Catalysis of the reaction: (2R)-3-amino-2-methylpropanoate + pyruvate = 2-methyl-3-oxopropanoate + L-alanine.
47306	D-methionine-pyruvate transaminase activity	F	Catalysis of the reaction: D-methionine + pyruvate = 4-methylthio-2-oxobutanoate + L-alanine.
47307	diaminobutyrate-pyruvate transaminase activity	F	Catalysis of the reaction: L-2,4-diaminobutyrate + pyruvate = L-alanine + L-aspartate 4-semialdehyde.
47308	alanine-oxomalonate transaminase activity	F	Catalysis of the reaction: L-alanine + oxomalonate = aminomalonate + pyruvate.
47309	dihydroxyphenylalanine transaminase activity	F	Catalysis of the reaction: 2-oxoglutarate + L-dopa = 3,4-dihydroxyphenylpyruvate + L-glutamate.
47310	glutamine-scyllo-inositol transaminase activity	F	Catalysis of the reaction: 2,4,6/3,5-pentahydroxycyclohexanone + L-glutamine = 1-amino-1-deoxy-scyllo-inositol + 2-oxoglutaramate.
47311	1D-1-guanidino-3-amino-1,3-dideoxy-scyllo-inositol transaminase activity	F	Catalysis of the reaction: 1D-1-guanidino-3-amino-1,3-dideoxy-scyllo-inositol + pyruvate = 1D-1-guanidino-1-deoxy-3-dehydro-scyllo-inositol + L-alanine.
47312	L-phenylalanine:pyruvate aminotransferase activity	F	Catalysis of the reaction: pyruvate + L-phenylalanine = phenylpyruvate + L-alanine.
47313	aromatic-amino-acid-glyoxylate transaminase activity	F	Catalysis of the reaction: glyoxylate + an aromatic amino acid = L-glycine + an aromatic oxo acid.
47315	kynurenine-glyoxylate transaminase activity	F	Catalysis of the reaction: L-kynurenine + glyoxylate = 4-(2-aminophenyl)-2,4-dioxobutanoate + glycine.
47316	glutamine-phenylpyruvate transaminase activity	F	Catalysis of the reaction: keto-phenylpyruvate + L-glutamine = 2-oxoglutaramate + L-phenylalanine.
47317	N6-acetyl-beta-lysine transaminase activity	F	Catalysis of the reaction: 2-oxoglutarate + 3-amino-6-acetamidohexanoate = L-glutamate + 3-oxo-6-acetamidohexanoate.
47319	aspartate-phenylpyruvate transaminase activity	F	Catalysis of the reaction: keto-phenylpyruvate + L-aspartate = L-phenylalanine + oxaloacetate.
47320	D-4-hydroxyphenylglycine transaminase activity	F	Catalysis of the reaction: 2-oxoglutarate + D-4-hydroxyphenylglycine = 4-hydroxyphenylglyoxylate + L-glutamate.
47321	diphosphate-protein phosphotransferase activity	F	Catalysis of the reaction: microsomal-membrane protein + diphosphate = diphosphate + O-phospho-microsomal-membrane protein.
47322	[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity	F	Catalysis of the reaction: [3-hydroxy-3-methylglutaryl-CoA reductase (NADPH)] + ATP = [3-hydroxy-3-methylglutaryl-CoA reductase (NADPH)] phosphate + ADP.
47323	[3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring)] kinase activity	F	Catalysis of the reaction: ATP + 3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring) = ADP + 3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring) phosphate.
47324	phosphoenolpyruvate-glycerone phosphotransferase activity	F	Catalysis of the reaction: glycerone + phosphoenolpyruvate = glycerone phosphate + pyruvate.
47325	inositol tetrakisphosphate 1-kinase activity	F	Catalysis of the reaction: 1D-myo-inositol 3,4,5,6-tetrakisphosphate + ATP = 1D-myo-inositol 1,3,4,5,6-pentakisphosphate + ADP.
47326	inositol tetrakisphosphate 5-kinase activity	F	Catalysis of the reaction: 1D-myo-inositol 1,3,4,6-tetrakisphosphate + ATP = 1D-myo-inositol 1,3,4,5,6-pentakisphosphate + ADP.
47327	glycerol-3-phosphate-glucose phosphotransferase activity	F	Catalysis of the reaction: sn-glycerol 3-phosphate + D-glucose = D-glucose 6-phosphate + glycerol.
47328	acyl-phosphate-hexose phosphotransferase activity	F	Catalysis of the reaction: D-hexose + acyl phosphate = D-hexose phosphate + an acid.
47329	phosphoramidate-hexose phosphotransferase activity	F	Catalysis of the reaction: hexose + phosphoramidate = hexose 1-phosphate + NH3.
47330	polyphosphate-glucose phosphotransferase activity	F	Catalysis of the reaction: beta-D-glucose + long chain polyphosphate = glucose-6-phosphate + long chain polyphosphate.
47331	diphosphate-glycerol phosphotransferase activity	F	Catalysis of the reaction: glycerol + diphosphate = glycerol 1-phosphate + H(+) + phosphate.
47332	diphosphate-serine phosphotransferase activity	F	Catalysis of the reaction: L-serine + diphosphate = O-phospho-L-serine + H(+) + phosphate.
47333	dihydrostreptomycin-6-phosphate 3'-alpha-kinase activity	F	Catalysis of the reaction: ATP + dihydrostreptomycin 6-phosphate = ADP + dihydrostreptomycin 3'alpha,6-bisphosphate + 2 H(+).
47334	diphosphate-fructose-6-phosphate 1-phosphotransferase activity	F	Catalysis of the reaction: fructose-6-phosphate + diphosphate = phosphate + fructose-1,6-bisphosphate.
47335	3-phosphoglyceroyl-phosphate-polyphosphate phosphotransferase activity	F	Catalysis of the reaction: long-chain-polyphosphate + 3-phospho-D-glyceroyl-phosphate = long-chain-polyphosphate + 3-phosphoglycerate.
47336	5-methyldeoxycytidine-5'-phosphate kinase activity	F	Catalysis of the reaction: 2'-deoxy-5-methyl-5'-cytidylate + ATP = 5-methyldeoxycytidine diphosphate + ADP + H(+).
47337	dolichyl-diphosphate-polyphosphate phosphotransferase activity	F	Catalysis of the reaction: dolichyl diphosphate + long-chain-polyphosphate = dolichol-phosphate + long-chain-polyphosphate.
47338	UTP:xylose-1-phosphate uridylyltransferase activity	F	Catalysis of the reaction: alpha-D-xylose 1-phosphate + UTP = UDP-D-xylose + diphosphate.
47339	nucleoside-triphosphate-hexose-1-phosphate nucleotidyltransferase activity	F	Catalysis of the reaction: hexose 1-phosphate + nucleoside triphosphate = NDP-hexose + diphosphate.
47341	fucose-1-phosphate guanylyltransferase activity	F	Catalysis of the reaction: beta-L-fucose 1-phosphate + GTP = diphosphate + GDP-L-fucose.
47342	galactose-1-phosphate thymidylyltransferase activity	F	Catalysis of the reaction: alpha-D-galactose 1-phosphate + dTTP = diphosphate + dTDP-D-galactose.
47343	glucose-1-phosphate cytidylyltransferase activity	F	Catalysis of the reaction: alpha-D-glucose 1-phosphate + CTP = CDP-D-glucose + diphosphate.
47344	glucose-1-phosphate guanylyltransferase activity	F	Catalysis of the reaction: alpha-D-glucose 1-phosphate + GTP = diphosphate + GDP-D-glucose.
47345	ribose-5-phosphate adenylyltransferase activity	F	Catalysis of the reaction: D-ribose 5-phosphate + ADP + H(+) = ADP-ribose + phosphate.
47346	aldose-1-phosphate adenylyltransferase activity	F	Catalysis of the reaction: aldose 1-phosphate + ADP = phosphate + ADP-aldose.
47347	aldose-1-phosphate nucleotidyltransferase activity	F	Catalysis of the reaction: aldose 1-phosphate + NDP = phosphate + NDP-aldose.
47348	glycerol-3-phosphate cytidylyltransferase activity	F	Catalysis of the reaction: sn-glycerol 3-phosphate + CTP = CDP-glycerol + diphosphate.
47349	D-ribitol-5-phosphate cytidylyltransferase activity	F	Catalysis of the reaction: D-ribitol 5-phosphate + CTP = CDP-ribitol + diphosphate.
47350	glucuronate-1-phosphate uridylyltransferase activity	F	Catalysis of the reaction: 1-phospho-alpha-D-glucuronate + UTP = diphosphate + UDP-alpha-D-glucuronate.
47351	guanosine-triphosphate guanylyltransferase activity	F	Catalysis of the reaction: 2 GTP = P(1),P(4)-bis(5'-guanosyl) tetraphosphate + diphosphate + H(+).
47352	adenylylsulfate-ammonia adenylyltransferase activity	F	Catalysis of the reaction: 5'-adenylyl sulfate + NH(4)(+) = adenosine 5'-phosphoramidate + 2 H(+) + sulfate.
47353	N-methylphosphoethanolamine cytidylyltransferase activity	F	Catalysis of the reaction: N-methylethanolamine phosphate + CTP = CDP-N-methylethanolamine + diphosphate.
47354	sphingosine cholinephosphotransferase activity	F	Catalysis of the reaction: CDP-choline + sphingosine = CMP + H(+) + sphingosyl-phosphocholine.
47355	CDP-glycerol glycerophosphotransferase activity	F	Catalysis of the reaction: glycerophosphate(n) + CDP-glycerol = glycerophosphate(n+1) + CMP.
47356	CDP-ribitol ribitolphosphotransferase activity	F	Catalysis of the reaction: ribitol phosphate(n) + CDP-ribitol = ribitol phosphate(n+1) + CMP.
47357	UDP-galactose-UDP-N-acetylglucosamine galactose phosphotransferase activity	F	Catalysis of the reaction: UDP-N-acetyl-alpha-D-glucosamine + UDP-D-galactose = H(+) + UDP-N-acetyl-6-(D-galactose-1-phospho)-D-glucosamine + UMP.
47358	UDP-glucose-glycoprotein glucose phosphotransferase activity	F	Catalysis of the reaction: glycoprotein D-mannose + UDP-D-glucose = glycoprotein 6-(D-glucose-1-phospho)-D-mannose + UMP.
47359	1-alkenyl-2-acylglycerol choline phosphotransferase activity	F	Catalysis of the reaction: 1-alkenyl-2-acylglycerol + CDP-choline = plasmenylcholine + CMP.
47360	undecaprenyl-phosphate galactose phosphotransferase activity	F	Catalysis of the reaction: all-trans-undecaprenyl phosphate + UDP-D-galactose = alpha-D-galactosyl-diphosphoundecaprenol + UMP.
47361	phosphomannan mannosephosphotransferase activity	F	Catalysis of the reaction: phosphomannan(n) + GDP-mannose = phosphomannan(n+1) + GMP.
47362	thiosulfate-dithiol sulfurtransferase activity	F	Catalysis of the reaction: dithioerythritol + thiosulfate = hydrogen sulfide + dithioerythritol disulfide + sulfite.
47363	triglucosylalkylacylglycerol sulfotransferase activity	F	Catalysis of the reaction: alpha-D-glucosyl-1,6-alpha-D-glucosyl-1,6-alpha-D-glucosyl-1,3-1-O-alkyl-2-O-acylglycerol + 3'-phosphoadenosine 5'-phosphosulfate = 6-sulfo-alpha-D-glucosyl-1,6-alpha-D-glucosyl-1,6-alpha-D-glucosyl-1,3-1-O-alkyl-2-O-acylglycerol + adenosine 3',5'-bisphosphate.
47364	desulfoglucosinolate sulfotransferase activity	F	Catalysis of the reaction: 3'-phospho-5'-adenylyl sulfate + desulfoglucotropeolin = adenosine 3',5'-diphosphate + glucotropeolin + H(+).
47365	quercetin-3-sulfate 3'-sulfotransferase activity	F	Catalysis of the reaction: 3'-phospho-5'-adenylyl sulfate + quercetin 3-sulfate = adenosine 3',5'-diphosphate + H(+) + quercetin 3,3'-disulfate.
47366	quercetin-3-sulfate 4'-sulfotransferase activity	F	Catalysis of the reaction: 3'-phospho-5'-adenylyl sulfate + quercetin 3-sulfate = adenosine 3',5'-diphosphate + H(+) + quercetin 3,4'-disulfate.
47367	quercetin-3,3'-bissulfate 7-sulfotransferase activity	F	Catalysis of the reaction: quercetin 3,3'-bissulfate + 3'-phosphoadenosine 5'-phosphosulfate = quercetin 3,3',7-trissulfate + adenosine 3',5'-bisphosphate.
47368	UDP-N-acetylgalactosamine-4-sulfate sulfotransferase activity	F	Catalysis of the reaction: 3'-phospho-5'-adenylyl sulfate + UDP-N-acetyl-D-galactosamine 4-sulfate = adenosine 3',5'-diphosphate + H(+) + UDP-N-acetyl-D-galactosamine 4,6-disulfate.
47369	succinate-hydroxymethylglutarate CoA-transferase activity	F	Catalysis of the reaction: (S)-3-hydroxy-3-methylglutarate + succinyl-CoA = 3-hydroxy-3-methyl-glutaryl-CoA + succinate.
47370	succinate-citramalate CoA-transferase activity	F	Catalysis of the reaction: S-citramalate + succinyl-CoA = citramalyl-CoA + succinate.
47371	butyrate-acetoacetate CoA-transferase activity	F	Catalysis of the reaction: acetoacetate + butanoyl-CoA = acetoacetyl-CoA + butanoate.
47372	acylglycerol lipase activity	F	Catalysis of the reaction: H2O + acylglycerol = a fatty acid + glycerol.
47373	acetoxybutynylbithiophene deacetylase activity	F	Catalysis of the reaction: 5-(4-acetoxybut-1-ynyl)-2,2'-bithiophene + H(2)O = 5-(4-hydroxy-but-1-ynyl)-2,2'-bithiophene + acetate + H(+).
47374	methylumbelliferyl-acetate deacetylase activity	F	Catalysis of the reaction: 4-methylumbelliferyl acetate + H(2)O = 4-methylumbelliferone + acetate + H(+).
47375	N-acetylgalactosaminoglycan deacetylase activity	F	Catalysis of the reaction: H2O + N-acetyl-D-galactosaminoglycan = acetate + D-galactosaminoglycan.
47376	all-trans-retinyl-palmitate hydrolase, all-trans-retinol forming activity	F	Catalysis of the reaction: all-trans-retinyl palmitate + H2O = all-trans-retinol + H+ + palmitate.
47377	5-(3,4-diacetoxybut-1-ynyl)-2,2'-bithiophene deacetylase activity	F	Catalysis of the reaction: 5-(3,4-diacetoxybut-1-ynyl)-2,2'-bithiophene + H(2)O = 5-(3-hydroxy-4-acetoxybut-1-ynyl)-2,2'-bithiophene + acetate + H(+).
47378	acetylalkylglycerol acetylhydrolase activity	F	Catalysis of the reaction: 2-acetyl-1-alkyl-sn-glycerol + H(2)O = 1-alkyl-sn-glycerol + acetate + H(+).
47379	ADP-dependent short-chain-acyl-CoA hydrolase activity	F	Catalysis of the reaction: H2O + a short-chain acyl-CoA = a short-chain carboxylate + CoA.
47380	ADP-dependent medium-chain-acyl-CoA hydrolase activity	F	Catalysis of the reaction: H2O + a medium-chain acyl-CoA = a medium-chain carboxylate + CoA. Requires ADP.
47381	dodecanoyl-[acyl-carrier-protein] hydrolase activity	F	Catalysis of the reaction: H2O + dodecanoyl-[acyl-carrier protein] = dodecanoate + [acyl-carrier protein].
47382	methylphosphothioglycerate phosphatase activity	F	Catalysis of the reaction: S-methyl-3-phospho-1-thio-D-glycerate + H(2)O = S-methyl-1-thio-D-glycerate + phosphate.
47383	guanidinodeoxy-scyllo-inositol-4-phosphatase activity	F	Catalysis of the reaction: 1-guanidino-1-deoxy-scyllo-inositol 4-phosphate + H(2)O = 1-guanidino-1-deoxy-scyllo-inositol + phosphate.
47384	[hydroxymethylglutaryl-CoA reductase (NADPH)]-phosphatase activity	F	Catalysis of the reaction: H2O + [hydroxymethylglutaryl-CoA reductase (NADPH)] phosphate = phosphate + [hydroxymethylglutaryl-CoA reductase (NADPH)].
47385	[3-methyl-2-oxobutanoate dehydrogenase (lipoamide)]-phosphatase activity	F	Catalysis of the reaction: H2O + [3-methyl-2-oxobutanoate dehydrogenase (lipoamide)] phosphate = phosphate + [3-methyl-2-oxobutanoate dehydrogenase (lipoamide)].
47386	fructose-2,6-bisphosphate 6-phosphatase activity	F	Catalysis of the reaction: beta-D-fructose 2,6-bisphosphate + H(2)O = beta-D-fructofuranose 2-phosphate + phosphate.
47387	serine-ethanolaminephosphate phosphodiesterase activity	F	Catalysis of the reaction: H(2)O + serine phosphoethanolamine = H(+) + phosphoethanolamine + serine.
47388	adenylyl-[glutamate-ammonia ligase] hydrolase activity	F	Catalysis of the reaction: adenylyl-[L-glutamate:ammonia ligase (ADP-forming)] + H2O = AMP + [L-glutamate:ammonia ligase (ADP-forming)].
47389	glycerophosphocholine phosphodiesterase activity	F	Catalysis of the reaction: H2O + L-1-glycero-3-phosphocholine = glycerol-3-phosphate + choline.
47390	glycerophosphocholine cholinephosphodiesterase activity	F	Catalysis of the reaction: sn-glycero-3-phosphocholine + H(2)O = choline phosphate + glycerol + H(+).
47391	alkylglycerophosphoethanolamine phosphodiesterase activity	F	Catalysis of the reaction: H2O + 1-alkyl-sn-glycero-3-phosphoethanolamine = ethanolamine + 1-alkyl-sn-glycerol 3-phosphate.
47392	CMP-N-acylneuraminate phosphodiesterase activity	F	Catalysis of the reaction: H2O + CMP-N-acylneuraminate = N-acylneuraminate + CMP.
47393	glycerol-1,2-cyclic-phosphate 2-phosphodiesterase activity	F	Catalysis of the reaction: glycerol 1,2-cyclic phosphate + H(2)O = glycerol 1-phosphate + H(+).
47394	glycerophosphoinositol inositolphosphodiesterase activity	F	Catalysis of the reaction: H2O + 1-(sn-glycero-3-phospho)-1D-myoinositol = 1D-myo-inositol 1-phosphate + glycerol.
47395	glycerophosphoinositol glycerophosphodiesterase activity	F	Catalysis of the reaction: 1-(sn-glycero-3-phospho)-1D-myo-inositol + H(2)O = sn-glycerol 3-phosphate + myo-inositol + H(+).
47396	glycosylphosphatidylinositol diacylglycerol-lyase activity	F	Catalysis of the reaction: 6-(alpha-D-glucosaminyl)-1-phosphatidyl-1D-myo-inositol = 1,2-diacyl-sn-glycerol + 6-(alpha-D-glucosaminyl)-1D-myo-inositol 1,2-cyclic phosphate.
47397	dolichylphosphate-glucose phosphodiesterase activity	F	Catalysis of the reaction: dolichyl beta-D-glucosyl phosphate + H2O = dolichol-phosphate + beta-D-glucose.
47398	dolichylphosphate-mannose phosphodiesterase activity	F	Catalysis of the reaction: dolichyl beta-D-mannosyl phosphate + H2O = dolichol-phosphate + mannose.
47399	glucose-1-phospho-D-mannosylglycoprotein phosphodiesterase activity	F	Catalysis of the reaction: H2O + 6-(D-glucose-1-phospho)-D-mannosylglycoprotein = D-mannosylglycoprotein + D-glucose-alpha-1-phosphate.
47400	phosphonoacetate hydrolase activity	F	Catalysis of the reaction: H(2)O + phosphonoacetate = acetate + H(+) + phosphate.
47401	trithionate hydrolase activity	F	Catalysis of the reaction: H(2)O + trithionate = H(+) + sulfate + thiosulfate.
47402	protein-glucosylgalactosylhydroxylysine glucosidase activity	F	Catalysis of the reaction: H2O + protein alpha-D-glucosyl-1,2-beta-D-galactosyl-L-hydroxylysine = protein beta-D-galactosyl-L-hydroxylysine + beta-D-glucose.
47403	lacto-N-biosidase activity	F	Catalysis of the reaction: H2O + beta-D-Gal-(1,3)-beta-D-GlcNAc-(1,3)-beta-D-Gal-(1,4)-D-Glc = beta-D-Gal-(1,4)-D-Glc + beta-D-Gal-(1,3)-D-GlcNAc.
47404	glucuronosyl-disulfoglucosamine glucuronidase activity	F	Catalysis of the reaction: H2O + 3-D-glucuronosyl-N2-,6-disulfo-beta-D-glucosamine = glucuronate + N2,6-disulfo-D-glucosamine.
47405	pyrimidine-5'-nucleotide nucleosidase activity	F	Catalysis of the reaction: H2O + a pyrimidine 5'-nucleotide = ribose-5-phosphate + a pyrimidine.
47406	beta-aspartyl-N-acetylglucosaminidase activity	F	Catalysis of the reaction: N(4)-(beta-N-acetyl-D-glucosaminyl)-L-asparagine + H(2)O = N-acetyl-D-glucosamine + L-asparagine.
47407	ADP-ribosyl-[dinitrogen reductase] hydrolase activity	F	Catalysis of the reaction: ADP-ribosyl-[dinitrogen reductase] = adenosine diphosphate ribose + [dinitrogen reductase].
47408	alkenylglycerophosphocholine hydrolase activity	F	Catalysis of the reaction: H2O + 1-(1-alkenyl)-sn-glycero-3-phosphocholine = L-1-glycero-3-phosphocholine + an aldehyde.
47409	alkenylglycerophosphoethanolamine hydrolase activity	F	Catalysis of the reaction: H2O + 1-(1-alkenyl)-sn-glycero-3-phosphoethanolamine = sn-glycero-3-phosphoethanolamine + an aldehyde.
47410	N-formylmethionylaminoacyl-tRNA deformylase activity	F	Catalysis of the reaction: H2O + charged-fMet-tRNAs = L-methionylaminoacyl-tRNA + formate.
47411	2-(acetamidomethylene)succinate hydrolase activity	F	Catalysis of the reaction: 2 H2O + 2-(acetamidomethylene)succinate = CO2 + NH3 + succinate semialdehyde + acetate.
47412	N-(long-chain-acyl)ethanolamine deacylase activity	F	Catalysis of the reaction: H2O + N-(long-chain-acyl)ethanolamine = ethanolamine + a fatty acid.
47413	N(alpha)-benzyloxycarbonylleucine hydrolase activity	F	Catalysis of the reaction: N-benzyloxycarbonyl-L-leucine + H(2)O + H(+) = L-leucine + benzyl alcohol + CO(2).
47414	2-(hydroxymethyl)-3-(acetamidomethylene)succinate hydrolase activity	F	Catalysis of the reaction: (2Z)-2-(acetamidomethylene)-3-(hydroxymethyl)succinate + 2 H(2)O + H(+) = 2-(hydroxymethyl)-4-oxobutanoate + acetate + CO(2) + NH(4)(+).
47415	D-benzoylarginine-4-nitroanilide amidase activity	F	Catalysis of the reaction: N(2)-benzoyl-D-arginine-4-nitroanilide + H(2)O = 4-nitroaniline + N(2)-benzoyl-D-arginine + H(+).
47416	arylalkyl acylamidase activity	F	Catalysis of the reaction: H2O + N-acetylarylalkylamine = acetate + arylalkylamine.
47417	N-carbamoyl-D-amino acid hydrolase activity	F	Catalysis of the reaction: H2O + N-carbamoyl-D-amino acid = CO2 + NH3 + D-amino acid.
47418	phthalyl amidase activity	F	Catalysis of the reaction: H2O + a phthalylamide = phthalate + substituted amine.
47419	N-acetylgalactosamine-6-phosphate deacetylase activity	F	Catalysis of the reaction: H2O + N-acetyl-D-galactosamine 6-phosphate = acetate + D-galactosamine 6-phosphate.
47420	N-acyl-D-amino-acid deacylase activity	F	Catalysis of the reaction: H2O + N-acyl-D-amino acid = D-amino acid + an acid.
47421	N-acyl-D-glutamate deacylase activity	F	Catalysis of the reaction: N-acyl-D-glutamate + H(2)O = D-glutamate + a carboxylate.
47422	N-acyl-D-aspartate deacylase activity	F	Catalysis of the reaction: N-acyl-D-aspartate + H(2)O = D-aspartate + a carboxylate.
47423	N-methylhydantoinase (ATP-hydrolyzing) activity	F	Catalysis of the reaction: N-methylhydantoin + ATP + 2 H(2)O = N-carbamoylsarcosine + ADP + 3 H(+) + phosphate.
47424	methylenediurea deaminase activity	F	Catalysis of the reaction: 2 H2O + methylenediurea = CO2 + 2 NH3 + N-hydroxymethylurea.
47425	1-pyrroline-4-hydroxy-2-carboxylate deaminase activity	F	Catalysis of the reaction: 4-hydroxy-1-pyrroline-2-carboxylate + H(2)O + H(+) = 2,5-dioxopentanoate + NH(4)(+).
47426	ricinine nitrilase activity	F	Catalysis of the reaction: H2O + ricinine = NH3 + 3-carboxy-4-methoxy-N-methyl-2-pyridone.
47427	cyanoalanine nitrilase activity	F	Catalysis of the reaction: 3-cyano-L-alanine + 2 H(2)O + H(+) = L-aspartate + NH(4)(+).
47428	arylacetonitrilase activity	F	Catalysis of the reaction: 2 H2O + 4-chlorophenylacetonitrile = 4-chlorophenylacetate + NH3.
47429	nucleoside-triphosphate diphosphatase activity	F	Catalysis of the reaction: H2O + a nucleoside triphosphate = diphosphate + a nucleotide.
47430	oligosaccharide-diphosphodolichol diphosphatase activity	F	Catalysis of the reaction: H2O + oligosaccharide-diphosphodolichol = dolichol-phosphate + oligosaccharide phosphate.
47431	3-hydroxy-2-methylpyridine-4,5-dicarboxylate 4-decarboxylase activity	F	Catalysis of the reaction: 5-hydroxy-6-methylpyridine-3,4-dicarboxylate + H(+) = 5-hydroxy-6-methylpyridine-3-carboxylate + CO(2).
47432	2,2-dialkylglycine decarboxylase (pyruvate) activity	F	Catalysis of the reaction: 2,2-dialkylglycine + H(+) + pyruvate = L-alanine + CO(2) + dialkyl ketone.
47433	branched-chain-2-oxoacid decarboxylase activity	F	Catalysis of the reaction: (S)-3-methyl-2-oxopentanoate + H(+) = 2-methylbutanal + CO(2).
47434	indolepyruvate decarboxylase activity	F	Catalysis of the reaction: indolepyruvate = CO2 + indole acetaldehyde.
47435	5-guanidino-2-oxopentanoate decarboxylase activity	F	Catalysis of the reaction: 5-guanidino-2-oxopentanoate + H(+) = 4-guanidinobutanal + CO(2).
47436	arylmalonate decarboxylase activity	F	Catalysis of the reaction: 2-aryl-2-methylmalonate + H(+) = 2-arylpropionate + CO(2).
47437	4-oxalocrotonate decarboxylase activity	F	Catalysis of the reaction: 4-oxalocrotonate = CO2 + 2-oxopent-4-enoate.
47438	2-dehydro-3-deoxy-L-pentonate aldolase activity	F	Catalysis of the reaction: 2-dehydro-3-deoxy-L-pentonate = glycolaldehyde + pyruvate.
47439	3-deoxy-D-manno-octulosonate aldolase activity	F	Catalysis of the reaction: 3-deoxy-D-manno-octulosonate = D-arabinose + pyruvate.
47440	2-dehydro-3-deoxy-D-pentonate aldolase activity	F	Catalysis of the reaction: 2-dehydro-3-deoxy-D-arabinonate = glycolaldehyde + pyruvate.
47441	5-dehydro-2-deoxyphosphogluconate aldolase activity	F	Catalysis of the reaction: 6-phospho-5-dehydro-2-deoxy-D-gluconate = 3-oxopropanoate + glycerone phosphate.
47442	17-alpha-hydroxyprogesterone aldolase activity	F	Catalysis of the reaction: 17-alpha-hydroxyprogesterone = acetaldehyde + 4-androstene-3,17-dione.
47443	4-hydroxy-4-methyl-2-oxoglutarate aldolase activity	F	Catalysis of the reaction: 4-hydroxy-4-methyl-2-oxoglutarate = 2 pyruvate.
47444	N-acylneuraminate-9-phosphate synthase activity	F	Catalysis of the reaction: H2O + phosphoenolpyruvate + N-acyl-D-mannosamine 6-phosphate = phosphate + N-acylneuraminate 9-phosphate.
47445	3-hydroxy-3-isohexenylglutaryl-CoA lyase activity	F	Catalysis of the reaction: 3-hydroxy-3-(4-methylpent-3-en-1-yl)glutaryl-CoA + 4 H(+) = 7-methyl-3-oxooct-6-enoyl-CoA + acetate.
47446	(1-hydroxycyclohexan-1-yl)acetyl-CoA lyase activity	F	Catalysis of the reaction: (1-hydroxycyclohexan-1-yl)acetyl-CoA = acetyl-CoA + cyclohexanone.
47447	erythro-3-hydroxyaspartate ammonia-lyase activity	F	Catalysis of the reaction: erythro-3-hydroxy-L-aspartate = NH3 + oxaloacetic acid.
47448	5-dehydro-4-deoxyglucarate dehydratase activity	F	Catalysis of the reaction: 5-dehydro-4-deoxy-D-glucarate + H(+) = 2,5-dioxopentanoate + CO(2) + H(2)O.
47449	2-dehydro-3-deoxy-L-arabinonate dehydratase activity	F	Catalysis of the reaction: 2-dehydro-3-deoxy-L-arabinonate = 2,5-dioxopentanoate + H(2)O.
47450	crotonoyl-[acyl-carrier-protein] hydratase activity	F	Catalysis of the reaction: (3R)-3-hydroxybutanoyl-[acyl-carrier protein] = H2O + but-2-enoyl-[acyl-carrier protein].
47451	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity	F	Catalysis of the reaction: (3R)-3-hydroxyoctanoyl-[acyl-carrier protein] = H2O + 2-octenoyl-[acyl-carrier protein].
47452	protoaphin-aglucone dehydratase (cyclizing) activity	F	Catalysis of the reaction: protoaphin aglucone = H(2)O + xanthoaphin.
47453	ATP-dependent NAD(P)H-hydrate dehydratase activity	F	Catalysis of the reaction: (6S)-6beta-hydroxy-1,4,5,6-tetrahydronicotinamide adenine dinucleotide + ATP = ADP + 3 H(+) + NADH + phosphate.
47454	phaseollidin hydratase activity	F	Catalysis of the reaction: phaseollidin hydrate = H(2)O + phaseollidin.
47455	16-alpha-hydroxyprogesterone dehydratase activity	F	Catalysis of the reaction: 16-alpha-hydroxyprogesterone = H2O + 16-dehydroprogesterone.
47456	2-methylisocitrate dehydratase activity	F	Catalysis of the reaction: (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate = cis-2-methylaconitate + H(2)O.
47457	exo-(1,4)-alpha-D-glucan lyase activity	F	Catalysis of the reaction: linear alpha-D-glucan = 1,5-anhydro-D-fructose + beta-D-glucose.
47458	beta-pyrazolylalanine synthase activity	F	Catalysis of the reaction: O-acetyl-L-serine + pyrazole = 3-(pyrazol-1-yl)-L-alanine + acetate + H(+).
47459	3-aminobutyryl-CoA ammonia-lyase activity	F	Catalysis of the reaction: (S)-3-aminobutanoyl-CoA = crotonoyl-CoA + NH(4)(+).
47460	L-2-amino-4-chloropent-4-enoate dehydrochlorinase activity	F	Catalysis of the reaction: L-2-amino-4-chloropent-4-enoate + H(2)O = 2-oxopent-4-enoate + chloride + H(+) + NH(4)(+).
47461	(+)-delta-cadinene synthase activity	F	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = diphosphate + (+)-delta-cadinene.
47462	phenylalanine racemase (ATP-hydrolyzing) activity	F	Catalysis of the reaction: L-phenylalanine + ATP + H(2)O = D-phenylalanine + AMP + diphosphate + 2 H(+).
47463	2-aminohexano-6-lactam racemase activity	F	Catalysis of the reaction: L-2-aminohexano-6-lactam = D-2-aminohexano-6-lactam.
47464	heparosan-N-sulfate-glucuronate 5-epimerase activity	F	Catalysis of the reaction: heparosan-N-sulfate D-glucuronate = heparosan-N-sulfate L-iduronate.
47465	N-acylglucosamine-6-phosphate 2-epimerase activity	F	Catalysis of the reaction: N-acyl-D-glucosamine 6-phosphate = N-acyl-D-mannosamine 6-phosphate.
47466	2-chloro-4-carboxymethylenebut-2-en-1,4-olide isomerase activity	F	Catalysis of the reaction: cis-2-chloro-4-carboxymethylenebut-2-en-1,4-olide = trans-2-chloro-4-carboxymethylenebut-2-en-1,4-olide.
47467	4-hydroxyphenylacetaldehyde-oxime isomerase activity	F	Catalysis of the reaction: (E)-4-hydroxyphenylacetaldehyde oxime = (Z)-4-hydroxyphenylacetaldehyde oxime.
47468	phosphoglucomutase (glucose-cofactor) activity	F	Catalysis of the reaction: glucose-1-phosphate = glucose-6-phosphate; using D-glucose as a cofactor.
47469	4-carboxymethyl-4-methylbutenolide mutase activity	F	Catalysis of the reaction: 4-carboxymethyl-4-methylbut-2-en-1,4-olide = 4-carboxymethyl-3-methylbut-2-en-1,4-olide.
47470	(1,4)-alpha-D-glucan 1-alpha-D-glucosylmutase activity	F	Catalysis of the reaction: 4-[(1->4)-alpha-D-glucosyl](n-1)-D-glucose = 1-alpha-D-[(1->4)-alpha-D-glucosyl](n-1)-alpha-D-glucopyranoside.
47471	maltose alpha-D-glucosyltransferase activity	F	Catalysis of the reaction: maltose = trehalose.
47472	3-carboxy-cis,cis-muconate cycloisomerase activity	F	Catalysis of the reaction: 2-(carboxymethyl)-5-oxo-2,5-dihydro-2-furoate = 3-carboxy-cis,cis-muconate + H(+).
47473	D-alanine-poly(phosphoribitol) ligase activity	F	Catalysis of the reaction: poly(ribitol phosphate) + D-alanine + ATP = O-D-alanyl-poly(ribitol phosphate) + diphosphate + AMP.
47474	long-chain fatty acid luciferin component ligase activity	F	Catalysis of the reaction: protein + an acid + ATP = an acyl-protein thiolester + diphosphate + AMP. A long-chain fatty acid is a fatty acid with a chain length between C13 and C22.
47475	phenylacetate-CoA ligase activity	F	Catalysis of the reaction: ATP + CoA + phenylacetate = AMP + diphosphate + H(+) + phenylacetyl-CoA.
47476	3-alpha,7-alpha-dihydroxy-5-beta-cholestanate-CoA ligase activity	F	Catalysis of the reaction: CoA + 3-alpha,7-alpha-dihydroxy-5-beta-cholestanate + ATP = 3-alpha,7-alpha-dihydroxy-5-beta-cholestanoyl-CoA + diphosphate + AMP.
47478	aspartate-ammonia ligase (ADP-forming) activity	F	Catalysis of the reaction: L-aspartate + ATP + NH(4)(+) = L-asparagine + ADP + 2 H(+) + phosphate.
47479	trypanothione synthase activity	F	Catalysis of the reaction: reduced glutathione + glutathionylspermidine + ATP = trypanothione + ADP + phosphate.
47480	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity	F	Catalysis of the reaction: UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysine + ATP + D-alanyl-D-alanine = phosphate + UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysyl-D-alanyl-D-alanine + ADP.
47481	D-alanine-alanyl-poly(glycerolphosphate) ligase activity	F	Catalysis of the reaction: alanyl-poly(glycerolphosphate) + D-alanine + ATP = D-alanyl-alanyl-poly(glycerolphosphate) + phosphate + ADP.
47482	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate-L-lysine ligase activity	F	Catalysis of the reaction: L-lysine + ATP + UDP-N-acetylmuramoyl-L-alanyl-D-glutamate = ADP + 2 H(+) + phosphate + UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-L-lysine.
47483	imidazoleacetate-phosphoribosyldiphosphate ligase activity	F	Catalysis of the reaction: 5-phospho-alpha-D-ribose 1-diphosphate + ATP + H(2)O + imidazol-4-ylacetate = 1-(5-phosphoribosyl)imidazol-4-ylacetate + ADP + diphosphate + 2 H(+) + phosphate.
47484	regulation of response to osmotic stress	P	Any process that modulates the rate or extent of the response to osmotic stress.
47485	protein N-terminus binding	F	Interacting selectively and non-covalently with a protein N-terminus, the end of any peptide chain at which the 2-amino (or 2-imino) function of a constituent amino acid is not attached in peptide linkage to another amino-acid residue.
47486	chondroitin ABC lyase activity	F	Catalysis of the eliminative degradation of polysaccharides containing 1,4-beta-D-hexosaminyl and 1,3-beta-D-glucuronosyl or 1,3-alpha-L-iduronosyl linkages to disaccharides containing 4-deoxy-beta-D-gluc-4-enuronosyl groups.
47487	oligogalacturonide lyase activity	F	Catalysis of the reaction: 4-(4-deoxy-alpha-D-gluc-4-enuronosyl)-D-galacturonate = 2 5-dehydro-4-deoxy-D-glucuronate.
47488	heparin lyase activity	F	Catalysis of the eliminative cleavage of polysaccharides containing 1,4-linked D-glucuronate or L-iduronate residues and 1,4-alpha-linked 2-sulfoamino-2-deoxy-6-sulfo-D-glucose residues to give oligosaccharides with terminal 4-deoxy-alpha-D-gluc-4-enuronosyl groups at their nonreducing ends.
47489	pectate disaccharide-lyase activity	F	Catalysis of the reaction: a pectate = a pectate + 4-(4-deoxy-alpha-D-galact-4-enuronosyl)-D-galacturonate. This reaction is the eliminative cleavage of 4-(4-deoxy-alpha-D-galact-4-enuronosyl)-D-galacturonate from the reducing end of pectate, i.e. de-esterified pectin.
47490	pectin lyase activity	F	Catalysis of the reaction: a pectin = an oligosaccharide with 4-deoxy-6-O-methyl-alpha-D-galact-4-enuronate end + a pectin. This reaction is the eliminative cleavage of (1->4)-alpha-D-galacturonan methyl ester to give oligosaccharides with 4-deoxy-6-O-methyl-alpha-D-galact-4-enuronosyl groups at their nonreducing ends.
47491	poly(alpha-L-guluronate) lyase activity	F	Catalysis of the reaction: polysaccharides containing a terminal alpha-L-guluronate group = oligosaccharides with 4-deoxy-alpha-L-erythro-hex-4-enuronosyl end. This reaction is the eliminative cleavage of polysaccharides containing a terminal a-L-guluronate group, to give oligopolysaccharides with 4-deoxy-a-L-erythro-hex-4-enuronosyl groups at their nonreducing ends.
47492	xanthan lyase activity	F	Catalysis of the reaction: xanthan = oligosaccharide with 4-deoxy-alpha-L-threo-hex-4-enuronosyl end + pyruvylate mannose. This reaction is the eliminative cleavage of the terminal beta-D-mannosyl-beta-D-1,4-glucuronosyl linkage of the side-chain of the polysaccharide xanthan, leaving a 4-deoxy-alpha-L-threo-hex-4-enuronosyl group at the terminus of the side-chain.
47493	ceramide cholinephosphotransferase activity	F	Catalysis of the reaction: CDP-choline + ceramide = CMP + H(+) + sphingomyelin.
47494	serine-phosphoethanolamine synthase activity	F	Catalysis of the reaction: L-serine + CDP-ethanolamine = L-serine-phosphoethanolamine + CMP + H(+).
47495	membrane-oligosaccharide glycerophosphotransferase activity	F	Catalysis of the transfer of a glycerophospho group from one membrane-derived oligosaccharide to another.
47496	vesicle transport along microtubule	P	The directed movement of a vesicle along a microtubule, mediated by motor proteins. This process begins with the attachment of a vesicle to a microtubule, and ends when the vesicle reaches its final destination.
47497	mitochondrion transport along microtubule	P	The directed movement of a mitochondrion along a microtubule, mediated by motor proteins.
47498	calcium-dependent phospholipase A2 activity	F	Catalysis of the reaction: phosphatidylcholine + H2O = 1-acylglycerophosphocholine + a carboxylate. This reaction requires Ca2+.
47499	calcium-independent phospholipase A2 activity	F	Catalysis of the reaction: phosphatidylcholine + H2O = 1-acylglycerophosphocholine + a carboxylate. This reaction does not require Ca2+.
47500	(+)-borneol dehydrogenase activity	F	Catalysis of the reaction: (+)-borneol + NAD(+) = (1R, 4R)-camphor + H(+) + NADH.
47501	(+)-neomenthol dehydrogenase activity	F	Catalysis of the reaction: (+)-neomenthol + NADP(+) = (2S,5R)-menthone + H(+) + NADPH.
47502	(+)-sabinol dehydrogenase activity	F	Catalysis of the reaction: (+)-cis-sabinol + NAD(+) = (1S,5S)-sabinone + H(+) + NADH.
47503	(-)-borneol dehydrogenase activity	F	Catalysis of the reaction: (-)-borneol + NAD(+) = (1S,4S)-camphor + H(+) + NADH.
47504	(-)-menthol dehydrogenase activity	F	Catalysis of the reaction: (-)-menthol + NADP(+) = (2S,5R)-menthone + H(+) + NADPH.
47505	(-)-menthol monooxygenase activity	F	Catalysis of the reaction: (-)-menthol + H(+) + NADPH + O(2) = 1,4-menthane-3,8-diol + H(2)O + NADP(+).
47506	(deoxy)adenylate kinase activity	F	Catalysis of the reaction: ATP + dAMP = ADP + dADP.
47507	(deoxy)nucleoside-phosphate kinase activity	F	Catalysis of the reaction: ATP + deoxynucleoside phosphate = ADP + deoxynucleoside diphosphate.
47508	(R)-2-methylmalate dehydratase activity	F	Catalysis of the reaction: (R)-citramalate = 2-methylmaleate + H(2)O.
47509	(R)-dehydropantoate dehydrogenase activity	F	Catalysis of the reaction: (R)-4-dehydropantoate + H(2)O + NAD(+) = (R)-3,3-dimethylmalate + 2 H(+) + NADH.
47510	(S)-2-methylmalate dehydratase activity	F	Catalysis of the reaction: S-citramalate = H(2)O + mesaconate.
47511	(S)-methylmalonyl-CoA hydrolase activity	F	Catalysis of the reaction: (S)-methylmalonyl-CoA + H(2)O = CoA + H(+) + methylmalonate.
47512	(S,S)-butanediol dehydrogenase activity	F	Catalysis of the reaction: (S,S)-butane-2,3-diol + NAD(+) = acetoin + H(+) + NADH.
47513	1,2-alpha-L-fucosidase activity	F	Catalysis of the reaction: H2O + methyl-2-alpha-L-fucopyranosyl-beta-D-galactoside = L-fucose + methyl beta-D-galactoside.
47514	1,3-beta-D-glucan phosphorylase activity	F	Catalysis of the reaction: [(1->3)-beta-D-glucosyl](n) + phosphate = [(1->3)-beta-D-glucosyl](n-1) + alpha-D-glucose 1-phosphate; substrates include laminarin.
47515	1,3-beta-oligoglucan phosphorylase activity	F	Catalysis of the reaction: [oligomeric (1->3)-beta-D-glucosyl](n) + phosphate = [(1->3)-beta-D-glucosyl](n-1) + alpha-D-glucose 1-phosphate.
47516	1,3-propanediol dehydrogenase activity	F	Catalysis of the reaction: propane-1,3-diol + NAD+ = 3-hydroxypropanal + NADH + H+.
47517	1,4-beta-D-xylan synthase activity	F	Catalysis of the reaction: UDP-D-xylose + [(1->4)-beta-D-xylan](n) = UDP + [(1->4)-beta-D-xylan](n+1).
47518	1-methyladenosine nucleosidase activity	F	Catalysis of the reaction: 1-methyladenosine + H(2)O = 1-methyladenine + ribofuranose.
47519	quinate dehydrogenase (quinone) activity	F	Catalysis of the reaction: (-)-quinate + pyrroloquinoline-quinone = (-)-3-dehydroquinate + pyrroloquinoline-quinol.
47520	11-cis-retinyl-palmitate hydrolase activity	F	Catalysis of the reaction: 11-cis-retinyl palmitate + H(2)O = 11-cis-retinol + H(+) + palmitate.
47521	3alpha,7alpha,12beta-trihydroxy-5beta-cholanate dehydrogenase activity	F	Catalysis of the reaction: 3alpha,7alpha,12beta-trihydroxy-5beta-cholanate + NADP(+) = 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanate + H(+) + NADPH.
47522	15-oxoprostaglandin 13-oxidase activity	F	Catalysis of the reaction: (5Z)-(15S)-11-alpha-hydroxy-9,15-dioxoprostanoate + NAD(P)+ -> (5Z)-(15S)-11-alpha-hydroxy-9,15-dioxoprosta-13-enoate + NAD(P)H + H+.
47524	16-hydroxysteroid epimerase activity	F	Catalysis of the reaction: 16-alpha-hydroxysteroid = 16-beta-hydroxysteroid.
47525	2'-hydroxydaidzein reductase activity	F	Catalysis of the reaction: 2'-hydroxydihydrodaidzein + NADP+ = 2'-hydroxydaidzein + NADPH + H+.
47526	2'-hydroxyisoflavone reductase activity	F	Catalysis of the reaction: vestitone + NADP+ = 2'-hydroxyformononetin + NADPH + H+.
47527	2,3-dihydroxybenzoate-serine ligase activity	F	Catalysis of the reaction: ATP + 2,3-dihydroxybenzoate + L-serine = products of ATP breakdown + N-(2,3-dihydroxybenzoyl)-L-serine.
47528	2,3-dihydroxyindole 2,3-dioxygenase activity	F	Catalysis of the reaction: 2,3-dihydroxyindole + O(2) = anthranilate + CO(2) + H(+).
47529	2,3-dimethylmalate lyase activity	F	Catalysis of the reaction: (2R,3S)-2,3-dimethylmalate = propanoate + pyruvate.
47530	2,4-diaminopentanoate dehydrogenase activity	F	Catalysis of the reaction: 2,4-diaminopentanoate + H2O + NAD(P)+ = 2-amino-4-oxopentanoate + NH3 + NAD(P)H + H+.
47531	2,5-diaminovalerate transaminase activity	F	Catalysis of the reaction: 2-oxoglutarate + ornithine = 5-amino-2-oxopentanoate + L-glutamate.
47532	2,5-dioxopiperazine hydrolase activity	F	Catalysis of the reaction: 2,5-dioxopiperazine + H(2)O = glycylglycine.
47533	2,5-dioxovalerate dehydrogenase (NADP+) activity	F	Catalysis of the reaction: 2,5-dioxopentanoate + NADP+ + H2O = 2-oxoglutarate + NADPH + H+.
47534	2-acetolactate mutase activity	F	Catalysis of the reaction: 2-acetolactate = 3-hydroxy-3-methyl-2-oxobutanoate.
47535	2-alkyn-1-ol dehydrogenase activity	F	Catalysis of the reaction: 2-butyne-1,4-diol + NAD(+) = 4-hydroxy-2-butynal + H(+) + NADH.
47536	2-aminoadipate transaminase activity	F	Catalysis of the reaction: 2-oxoglutarate + L-2-aminoadipate = 2-oxoadipate + L-glutamate.
47537	2-aminohexanoate transaminase activity	F	Catalysis of the reaction: L-2-aminohexanoate + 2-oxoglutarate = 2-oxohexanoate + L-glutamate.
47538	2-carboxy-D-arabinitol-1-phosphatase activity	F	Catalysis of the reaction: 2-carboxy-D-arabinitol 1-phosphate + H(2)O = 2-carboxy-D-arabinitol + phosphate.
47539	2-deoxyglucosidase activity	F	Catalysis of the reaction: H2O + a 2-deoxy-alpha-D-glucoside = 2-deoxy-D-glucose + an alcohol.
47540	2-enoate reductase activity	F	Catalysis of the reaction: butanoate + NAD+ = 2-butenoate + NADH + H+.
47541	2-furoate-CoA ligase activity	F	Catalysis of the reaction: 2-furoate + ATP + CoA = 2-furoyl-CoA + AMP + diphosphate + H(+).
47542	2-furoyl-CoA dehydrogenase activity	F	Catalysis of the reaction: 2-furoyl-CoA + A + H(2)O = 5-hydroxy-2-furoyl-CoA + AH(2) + H(+).
47543	2-hexadecenal reductase activity	F	Catalysis of the reaction: NADP(+) + palmitaldehyde = trans-hexadec-2-enal + H(+) + NADPH.
47544	2-hydroxybiphenyl 3-monooxygenase activity	F	Catalysis of the reaction: biphenyl-2-ol + H(+) + NADH + O(2) = biphenyl-2,3-diol + H(2)O + NAD(+).
47545	2-hydroxyglutarate dehydrogenase activity	F	Catalysis of the reaction: (S)-2-hydroxyglutarate + acceptor = 2-oxoglutarate + reduced acceptor.
47546	2-hydroxypyridine 5-monooxygenase activity	F	Catalysis of the reaction: 2-hydroxypyridine + AH(2) + O(2) = 2,5-dihydroxypyridine + A + H(2)O.
47547	2-methylcitrate dehydratase activity	F	Catalysis of the reaction: (2S,3S)-2-methylcitrate = cis-2-methylaconitate + H(2)O.
47548	2-methyleneglutarate mutase activity	F	Catalysis of the reaction: 2-methyleneglutarate = 2-methylene-3-methylsuccinate.
47549	2-nitrophenol 2-monooxygenase activity	F	Catalysis of the reaction: 2-nitrophenol + 2 H(+) + 2 NADPH + O(2) = catechol + H(2)O + 2 NADP(+) + nitrite.
47550	2-oxoadipate reductase activity	F	Catalysis of the reaction: 2-hydroxyadipate + NAD(+) = 2-oxoadipate + H(+) + NADH.
47551	2-oxoaldehyde dehydrogenase (NAD) activity	F	Catalysis of the reaction: a 2-oxoaldehyde + NAD+ + H2O = a 2-oxo acid + NADH + H+.
47552	2-oxoaldehyde dehydrogenase (NADP+) activity	F	Catalysis of the reaction: a 2-oxoaldehyde + NADP+ + H2O = a 2-oxo acid + NADPH + H+.
47553	2-oxoglutarate synthase activity	F	Catalysis of the reaction: 2-oxoglutarate + CoA + oxidized ferredoxin = succinyl-CoA + CO2 + reduced ferredoxin.
47554	2-pyrone-4,6-dicarboxylate lactonase activity	F	Catalysis of the reaction: 2-oxo-2H-pyran-4,6-dicarboxylate + H(2)O = 4-carboxy-2-hydroxyhexa-2,4-dienedioate + H(+).
47555	3',5'-cyclic-GMP phosphodiesterase activity	F	Catalysis of the reaction: guanosine 3',5'-cyclic phosphate + H2O = guanosine 5'-phosphate.
47556	3,4-dihydroxyphthalate decarboxylase activity	F	Catalysis of the reaction: 3,4-dihydroxyphthalate + H(+) = 3,4-dihydroxybenzoate + CO(2).
47557	3-aci-nitropropanoate oxidase activity	F	Catalysis of the reaction: 3-aci-nitropropanoate + H(2)O + O(2) = 3-oxopropanoate + H(2)O(2) + nitrite.
47558	3-cyanoalanine hydratase activity	F	Catalysis of the reaction: L-asparagine = 3-cyano-L-alanine + H(2)O + H(+).
47559	3-dehydro-L-gulonate 2-dehydrogenase activity	F	Catalysis of the reaction: 3-dehydro-L-gulonate + NAD(P)+ = (4R,5S)-4,5,6-trihydroxy-2,3-dioxohexanoate + NAD(P)H + H+.
47560	3-dehydrosphinganine reductase activity	F	Catalysis of the reaction: NADP(+) + sphinganine = 3-dehydrosphinganine + H(+) + NADPH.
47561	3-hydroxyanthranilate oxidase activity	F	Catalysis of the reaction: 3-hydroxyanthranilate + O(2) = 6-imino-5-oxocyclohexa-1,3-dienecarboxylate + H(2)O(2).
47562	3-hydroxyaspartate aldolase activity	F	Catalysis of the reaction: (3R)-3-hydroxy-L-aspartate = glycine + glyoxylate.
47563	3-hydroxybenzoate 2-monooxygenase activity	F	Catalysis of the reaction: 3-hydroxybenzoate + AH(2) + O(2) = 2,3-dihydroxybenzoate + A + H(2)O.
47564	3-hydroxycyclohexanone dehydrogenase activity	F	Catalysis of the reaction: 3-hydroxycyclohexanone + A = AH(2) + cyclohexane-1,3-dione.
47565	3-hydroxypropionate dehydrogenase (NAD+) activity	F	Catalysis of the reaction: 3-hydroxypropanoate + NAD(+) = 3-oxopropanoate + H(+) + NADH.
47566	3-ketovalidoxylamine C-N-lyase activity	F	Catalysis of the reaction: 4-nitrophenyl-3-ketovalidamine = 4-nitroaniline + 5-D-(5/6)-5-C-(hydroxymethyl)-2,6-dihydroxycyclohex-2-en-1-one + H(+).
47567	3-methyleneoxindole reductase activity	F	Catalysis of the reaction: 3-methyloxindole + NADP(+) = 3-methyleneoxindole + H(+) + NADPH.
47568	3-oxo-5-beta-steroid 4-dehydrogenase activity	F	Catalysis of the reaction: a 3-oxo-5-beta-steroid + acceptor = a 3-oxo-D4-steroid + reduced acceptor.
47569	3-oxoadipate CoA-transferase activity	F	Catalysis of the reaction: succinyl-CoA + 3-oxoadipate = succinate + 3-oxoadipyl-CoA.
47570	3-oxoadipate enol-lactonase activity	F	Catalysis of the reaction: 3-oxoadipate enol-lactone + H2O = 3-oxoadipate.
47571	3-oxosteroid 1-dehydrogenase activity	F	Catalysis of the reaction: a 3-oxosteroid + acceptor = a 3-oxo-D1-steroid + reduced acceptor.
47572	3-phosphoglycerate phosphatase activity	F	Catalysis of the reaction: 3-phospho-D-glycerate + H(2)O = D-glycerate + phosphate.
47573	4-acetamidobutyrate deacetylase activity	F	Catalysis of the reaction: 4-acetamidobutanoate + H2O = acetate + 4-aminobutanoate.
47574	4-acetamidobutyryl-CoA deacetylase activity	F	Catalysis of the reaction: 4-acetamidobutanoyl-CoA + H(2)O = 4-aminobutanoyl-CoA + acetate.
47575	4-carboxymuconolactone decarboxylase activity	F	Catalysis of the reaction: (R)-2-(carboxymethyl)-5-oxo-2,5-dihydro-2-furoate + H(+) = 5-oxo-4,5-dihydro-2-furylacetate + CO(2).
47576	4-chlorobenzoate dehalogenase activity	F	Catalysis of the reaction: 4-chlorobenzoate + H(2)O = 4-hydroxybenzoate + chloride + H(+).
47577	4-hydroxybutyrate dehydrogenase activity	F	Catalysis of the reaction: 4-hydroxybutanoate + NAD(+) = H(+) + NADH + succinate semialdehyde.
47578	4-hydroxyglutamate transaminase activity	F	Catalysis of the reaction: 4-hydroxy-L-glutamate + 2-oxoglutarate = 4-hydroxy-2-oxoglutarate + L-glutamate.
47579	4-hydroxymandelate oxidase activity	F	Catalysis of the reaction: (S)-4-hydroxymandelate + H(+) + O(2) = 4-hydroxybenzaldehyde + CO(2) + H(2)O(2).
47580	4-hydroxyproline epimerase activity	F	Catalysis of the reaction: trans-4-hydroxy-L-proline = cis-4-hydroxy-D-proline.
47581	4-methyleneglutamate-ammonia ligase activity	F	Catalysis of the reaction: 4-methylene-L-glutamate + ATP + NH(4)(+) = 4-methylene-L-glutamine + AMP + diphosphate + 2 H(+).
47582	4-methyleneglutaminase activity	F	Catalysis of the reaction: 4-methylene-L-glutamine + H(2)O = 4-methylene-L-glutamate + NH(4)(+).
47583	4-methyloxaloacetate esterase activity	F	Catalysis of the reaction: 4-methoxy-2,4-dioxobutanoate + H(2)O = H(+) + methanol + oxaloacetate.
47584	4-oxalmesaconate hydratase activity	F	Catalysis of the reaction: 2-hydroxy-4-oxobutane-1,2,4-tricarboxylate = (1E)-4-oxobut-1-ene-1,2,4-tricarboxylate + H(2)O.
47585	4-pyridoxolactonase activity	F	Catalysis of the reaction: 4-pyridoxolactone + H(2)O = 4-pyridoxate + H(+).
47586	5'-acylphosphoadenosine hydrolase activity	F	Catalysis of the reaction: 5'-acylphosphoadenosine + H2O = AMP + a carboxylate.
47587	5-alpha-hydroxysteroid dehydratase activity	F	Catalysis of the reaction: 5alpha-ergosta-7,22-diene-3beta,5-diol = ergosterol + H(2)O.
47588	5-aminopentanamidase activity	F	Catalysis of the reaction: 5-aminopentanamide + H2O = 5-aminopentanoate + NH3.
47589	5-aminovalerate transaminase activity	F	Catalysis of the reaction: 2-oxoglutarate + 5-aminopentanoate = 5-oxopentanoate + L-glutamate.
47590	5-dehydro-2-deoxygluconokinase activity	F	Catalysis of the reaction: ATP + 5-dehydro-2-deoxy-D-gluconate = ADP + 6-phospho-5-dehydro-2-deoxy-D-gluconate.
47591	5-hydroxypentanoate CoA-transferase activity	F	Catalysis of the reaction: 5-hydroxypentanoate + acetyl-CoA = 5-hydroxy-pentanoyl-CoA + acetate.
47592	5-pyridoxate dioxygenase activity	F	Catalysis of the reaction: 5-pyridoxate + NADPH + O(2) = (2Z)-2-(acetamidomethylene)-3-(hydroxymethyl)succinate + NADP(+).
47593	6-acetylglucose deacetylase activity	F	Catalysis of the reaction: 6-acetyl-D-glucose + H(2)O = D-glucose + acetate + H(+).
47594	6-beta-hydroxyhyoscyamine epoxidase activity	F	Catalysis of the reaction: (6S)-6-hydroxyhyoscyamine + 2-oxoglutarate + O(2) = CO(2) + H(2)O + H(+) + scopolamine + succinate.
47595	6-hydroxynicotinate reductase activity	F	Catalysis of the reaction: 1,4,5,6-tetrahydro-6-oxonicotinate + oxidized ferredoxin = 6-hydroxynicotinate + reduced ferredoxin.
47596	6-methylsalicylate decarboxylase activity	F	Catalysis of the reaction: 6-methylsalicylate + H(+) = 3-cresol + CO(2).
47597	6-oxocineole dehydrogenase activity	F	Catalysis of the reaction: 6-oxocineole + H(+) + NADPH + O(2) = 1,6,6-trimethyl-2,7-dioxabicyclo[3.2.2]nonan-3-one + H(2)O + NADP(+).
47598	7-dehydrocholesterol reductase activity	F	Catalysis of the reaction: cholesterol + NADP+ = cholesta-5,7-dien-3-beta-ol + NADPH + H+.
47599	8-oxocoformycin reductase activity	F	Catalysis of the reaction: coformycin + NADP(+) = 8-oxocoformycin + 2 H(+) + NADPH.
47600	abequosyltransferase activity	F	Catalysis of the reaction: CDP-abequose + D-mannosyl-L-rhamnosyl-D-galactose-1-diphospholipid = CDP + D-abequosyl-D-mannosyl-rhamnosyl-D-galactose-1-diphospholipid.
47601	acetate kinase (diphosphate) activity	F	Catalysis of the reaction: acetate + diphosphate = acetyl phosphate + phosphate.
47602	acetoacetate decarboxylase activity	F	Catalysis of the reaction: acetoacetate + H(+) = acetone + CO(2).
47603	acetoacetyl-CoA hydrolase activity	F	Catalysis of the reaction: acetoacetyl-CoA + H(2)O = acetoacetate + CoA + H(+).
47604	acetoin racemase activity	F	Catalysis of the reaction: (S)-acetoin = (R)-acetoin.
47605	acetolactate decarboxylase activity	F	Catalysis of the reaction: (S)-2-hydroxy-2-methyl-3-oxobutanoate = (R)-2-acetoin + CO2.
47606	hydroxynitrilase activity	F	Catalysis of the reaction: a hydroxynitrile = cyanide + an aldehyde or ketone.
47608	acetylindoxyl oxidase activity	F	Catalysis of the reaction: N-acetylindoxyl + O2 = N-acetylisatin + unknown.
47609	acetylputrescine deacetylase activity	F	Catalysis of the reaction: N-acetylputrescine + H(2)O = acetate + putrescine.
47610	acetylsalicylate deacetylase activity	F	Catalysis of the reaction: acetylsalicylate + H(2)O = acetate + H(+) + salicylate.
47611	acetylspermidine deacetylase activity	F	Catalysis of the reaction: N(8)-acetylspermidine + H(2)O = acetate + spermidine.
47612	acid-CoA ligase (GDP-forming) activity	F	Catalysis of the reaction: a carboxylate + CoA + GTP = acyl-CoA + GDP + H(+) + phosphate.
47613	aconitate decarboxylase activity	F	Catalysis of the reaction: cis-aconitate + H(+) = CO(2) + itaconate.
47614	aconitate delta-isomerase activity	F	Catalysis of the reaction: trans-aconitate = cis-aconitate.
47615	actinomycin lactonase activity	F	Catalysis of the reaction: actinomycin + H2O = actinomycinic monolactone.
47616	acyl-CoA dehydrogenase (NADP+) activity	F	Catalysis of the reaction: acyl-CoA + NADP+ = 2,3-dehydroacyl-CoA + NADPH + H+.
47617	acyl-CoA hydrolase activity	F	Catalysis of the reaction: acyl-CoA + H2O = CoA + a carboxylate.
47618	acylagmatine amidase activity	F	Catalysis of the reaction: N(4)-benzoylagmatine + H(2)O = agmatine + benzoate.
47619	acylcarnitine hydrolase activity	F	Catalysis of the reaction: O-acylcarnitine + H2O = a fatty acid + L-carnitine.
47620	acylglycerol kinase activity	F	Catalysis of the reaction: ATP + acylglycerol = ADP + acyl-sn-glycerol 3-phosphate.
47621	acylpyruvate hydrolase activity	F	Catalysis of the reaction: a 3-acylpyruvate + H2O = a carboxylate + pyruvate.
47622	adenosine nucleosidase activity	F	Catalysis of the reaction: adenosine + H2O = D-ribose + adenine.
47623	adenosine-phosphate deaminase activity	F	Catalysis of the reaction: an adenosine-phosphate + H20 = an inosine phosphate + NH3. Catalyzes the deamination of AMP, ADP or ATP.
47624	adenosine-tetraphosphatase activity	F	Catalysis of the reaction: adenosine 5'-tetraphosphate + H2O = ATP + phosphate.
47625	adenosylmethionine cyclotransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine(1+) = S-methyl-5'-thioadenosine + homoserine lactone.
47626	adenosylmethionine hydrolase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + H(2)O = S-methyl-5'-thioadenosine + L-homoserine + H(+).
47627	adenylylsulfatase activity	F	Catalysis of the reaction: 5'-adenylyl sulfate + H(2)O = AMP + 2 H(+) + sulfate.
47628	ADP-thymidine kinase activity	F	Catalysis of the reaction: ADP + thymidine = AMP + thymidine 5'-phosphate.
47629	ADP deaminase activity	F	Catalysis of the reaction: ADP + H2O = IDP + NH3.
47630	ADP-phosphoglycerate phosphatase activity	F	Catalysis of the reaction: 3-ADP-2-phosphoglycerate + H(2)O = 3-ADP-glycerate + phosphate.
47631	ADP-ribose diphosphatase activity	F	Catalysis of the reaction: ADP-ribose + H2O = AMP + D-ribose 5-phosphate.
47632	agmatine deiminase activity	F	Catalysis of the reaction: agmatine + H2O = N-carbamoylputrescine + NH3.
47633	agmatine kinase activity	F	Catalysis of the reaction: agmatine + ATP = N(4)-phosphoagmatine + ADP + 3 H(+).
47634	agmatine N4-coumaroyltransferase activity	F	Catalysis of the reaction: 4-coumaroyl-CoA + agmatine = N-(4-guanidiniumylbutyl)-4-hydroxycinnamamide + CoA + H(+).
47635	alanine-oxo-acid transaminase activity	F	Catalysis of the reaction: L-alanine + a 2-oxo acid = pyruvate + an L-amino acid.
47636	alanopine dehydrogenase activity	F	Catalysis of the reaction: 2,2'-iminodipropanoate + H(2)O + NAD(+) = L-alanine + H(+) + NADH + pyruvate.
47637	alanylphosphatidylglycerol synthase activity	F	Catalysis of the reaction: L-alanyl-tRNA + phosphatidylglycerol = tRNA + 3-O-L-alanyl-1-O-phosphatidylglycerol.
47638	albendazole monooxygenase activity	F	Catalysis of the reaction: albendazole + H(+) + NADPH + O(2) = albendazole S-oxide + H(2)O + NADP(+).
47639	alcohol oxidase activity	F	Catalysis of the reaction: a primary alcohol + O2 = an aldehyde + H2O2.
47640	aldose 1-dehydrogenase activity	F	Catalysis of the reaction: D-aldose + NAD+ = D-aldonolactone + NADH.
47641	aldose-6-phosphate reductase (NADPH) activity	F	Catalysis of the reaction: D-glucitol 6-phosphate + NADP(+) = D-glucose 6-phosphate + H(+) + NADPH.
47642	aldose beta-D-fructosyltransferase activity	F	Catalysis of the reaction: alpha-D-aldosyl1 beta-D-fructoside + D-aldose2 = D-aldose1 + alpha-D-aldosyl2 beta-D-fructoside.
47643	alginate synthase activity	F	Catalysis of the reaction: GDP-D-mannuronate + alginate(n) = GDP + alginate(n+1).
47644	alizarin 2-beta-glucosyltransferase activity	F	Catalysis of the reaction: alizarin + UDP-D-glucose = 1-hydroxy-2-(beta-D-glucosyloxy)-9,10-anthraquinone + H(+) + UDP.
47645	alkan-1-ol dehydrogenase (acceptor) activity	F	Catalysis of the reaction: primary alcohol + acceptor = aldehyde + reduced acceptor.
47646	alkanal monooxygenase (FMN-linked) activity	F	Catalysis of the reaction: R-CHO + reduced FMN + O2 = R-COOH + FMN + H2O + light.
47647	alkylacetylglycerophosphatase activity	F	Catalysis of the reaction: 1-alkyl-2-acetyl-sn-glycerol 3-phosphate + H(2)O = 2-acetyl-1-alkyl-sn-glycerol + phosphate.
47648	alkylamidase activity	F	Catalysis of the reaction: N-methylhexanamide + H(2)O = hexanoate + methylammonium.
47649	alkylglycerol kinase activity	F	Catalysis of the reaction: 1-alkyl-sn-glycerol + ATP = 1-alkyl-sn-glycerol 3-phosphate + ADP + 2 H(+).
47650	alkylglycerone kinase activity	F	Catalysis of the reaction: O-alkylglycerone + ATP = O-alkylglycerone phosphate + ADP + 2 H(+).
47651	alkylhalidase activity	F	Catalysis of the reaction: bromochloromethane + H(2)O = bromide + chloride + formaldehyde + 2 H(+).
47652	allantoate deiminase activity	F	Catalysis of the reaction: allantoate + H2O + H+ = CO2 + NH3 + ureidoglycine.
47653	allantoin racemase activity	F	Catalysis of the reaction: (S)-(+)-allantoin = (R)-(-)-allantoin.
47654	alliin lyase activity	F	Catalysis of the reaction: an S-alkyl-L-cysteine S-oxide = an alkyl sulfenate + 2-aminoacrylate.
47655	allyl-alcohol dehydrogenase activity	F	Catalysis of the reaction: allyl alcohol + NADP(+) = acrolein + H(+) + NADPH.
47656	alpha,alpha-trehalose phosphorylase activity	F	Catalysis of the reaction: alpha,alpha-trehalose + phosphate = D-glucose + beta-D-glucose 1-phosphate.
47657	alpha-1,3-glucan synthase activity	F	Catalysis of the reaction: UDP-glucose + [alpha-D-glucosyl-(1,3)]n = UDP + [alpha-D-glucosyl-(1,3)]n+1.
47658	alpha-amino-acid esterase activity	F	Catalysis of the reaction: an alpha-amino acid ester + H2O = an alpha-amino acid + an alcohol.
47659	alpha-santonin 1,2-reductase activity	F	Catalysis of the reaction: 1,2-dihydrosantonin + NAD(P)+ = alpha-santonin + NAD(P)H + H+.
47660	amidinoaspartase activity	F	Catalysis of the reaction: N-amidino-L-aspartate + H(2)O = L-aspartate + urea.
47661	amino-acid racemase activity	F	Catalysis of the reaction: an L-amino acid = a D-amino acid.
47662	aminobenzoate decarboxylase activity	F	Catalysis of the reaction: 4(or 2)-aminobenzoate = aniline + CO2.
47663	aminoglycoside 6'-N-acetyltransferase activity	F	Catalysis of the reaction: acetyl-CoA + kanamycin B = N(6')-acetylkanamycin B + CoA + H(+). This is acetylation of the 6'-amino group of the 6-deoxy-6-aminoglucose ring.
47664	aminoimidazolase activity	F	Catalysis of the reaction: 4-aminoimidazole + H2O = unidentified product + NH3.
47665	aminolevulinate transaminase activity	F	Catalysis of the reaction: 5-aminolevulinate + pyruvate = 4,5-dioxopentanoate + L-alanine.
47666	ammonia kinase activity	F	Catalysis of the reaction: ATP + NH(4)(+) = ADP + 3 H(+) + phosphoramidate.
47667	AMP-thymidine kinase activity	F	Catalysis of the reaction: AMP + thymidine = adenosine + thymidine 5'-phosphate.
47668	amygdalin beta-glucosidase activity	F	Catalysis of the reaction: (R)-amygdalin + H(2)O = (R)-prunasin + D-glucose.
47669	amylosucrase activity	F	Catalysis of the reaction: sucrose + 1,4-alpha-D-glucosyl(n) = D-fructose + 1,4-alpha-D-glucosyl(n+1).
47670	anhydrotetracycline monooxygenase activity	F	Catalysis of the reaction: anhydrotetracycline + H(+) + NADPH + O(2) = 12-dehydrotetracycline + H(2)O + NADP(+).
47671	anthranilate adenylyltransferase activity	F	Catalysis of the reaction: anthranilate + ATP = N-adenylylanthranilate + diphosphate + H(+).
47672	anthranilate N-benzoyltransferase activity	F	Catalysis of the reaction: anthranilate + benzoyl-CoA = N-benzoylanthranilate + CoA.
47673	anthranilate N-malonyltransferase activity	F	Catalysis of the reaction: anthranilate + malonyl-CoA = N-malonylanthranilate + CoA.
47674	apiose 1-reductase activity	F	Catalysis of the reaction: D-apiitol + NAD(+) = D-apiose + H(+) + NADH.
47675	arabinonate dehydratase activity	F	Catalysis of the reaction: D-arabinonate = 2-dehydro-3-deoxy-D-arabinonate + H(2)O.
47676	arachidonate-CoA ligase activity	F	Catalysis of the reaction: arachidonate + ATP + CoA = AMP + arachidonoyl-CoA + diphosphate + H(+).
47677	arachidonate 8(R)-lipoxygenase activity	F	Catalysis of the reaction: arachidonate + O(2) = (5Z,8R,9E,11Z,14Z)-8-hydroperoxyicosa-5,9,11,14-tetraenoate.
47678	arginine 2-monooxygenase activity	F	Catalysis of the reaction: L-arginine + O(2) = 4-guanidinobutanamide + CO(2) + H(2)O.
47679	arginine racemase activity	F	Catalysis of the reaction: L-arginine = D-arginine.
47680	aryl-acylamidase activity	F	Catalysis of the reaction: anilide + H(2)O = a carboxylate + aniline + H(+).
47681	aryl-alcohol dehydrogenase (NADP+) activity	F	Catalysis of the reaction: an aromatic alcohol + NADP+ = an aromatic aldehyde + NADPH.
47682	aryl-alcohol oxidase activity	F	Catalysis of the reaction: an aromatic primary alcohol + O2 = an aromatic aldehyde + H2O2.
47683	aryl-aldehyde dehydrogenase (NADP+) activity	F	Catalysis of the reaction: an aromatic aldehyde + NADP+ + AMP + diphosphate + H2O = an aromatic acid + NADPH + ATP.
47684	arylamine glucosyltransferase activity	F	Catalysis of the reaction: UDP-glucose + an arylamine = UDP + an N-D-glucosylarylamine.
47685	amine sulfotransferase activity	F	Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + an amine = adenosine 3',5'-bisphosphate + a sulfamate.
47686	arylsulfate sulfotransferase activity	F	Catalysis of the reaction: an aryl sulfate + a phenol = a phenol + an aryl sulfate.
47688	aspartate 4-decarboxylase activity	F	Catalysis of the reaction: L-aspartate = L-alanine + CO2.
47689	aspartate racemase activity	F	Catalysis of the reaction: L-aspartate = D-aspartate.
47690	aspartyltransferase activity	F	Catalysis of the reaction: L-asparagine + H(+) + hydroxylamine = beta-L-aspartylhydroxamate + NH(4)(+).
47691	aspulvinone dimethylallyltransferase activity	F	Catalysis of the reaction: aspulvinone E + 2 dimethylallyl diphosphate = aspulvinone H + 2 diphosphate.
47692	ATP deaminase activity	F	Catalysis of the reaction: ATP + H2O = ITP + NH3.
47693	ATP diphosphatase activity	F	Catalysis of the reaction: ATP + H2O = AMP + diphosphate.
47694	barbiturase activity	F	Catalysis of the reaction: barbiturate + H2O = malonate + urea.
47695	benzoin aldolase activity	F	Catalysis of the reaction: benzoin = 2 benzaldehyde.
47696	beta-adrenergic receptor kinase activity	F	Catalysis of the reaction: ATP + beta-adrenergic receptor = ADP + phospho-beta-adrenergic receptor.
47697	beta-alanopine dehydrogenase activity	F	Catalysis of the reaction: (R)-beta-alanopine + H(2)O + NAD(+) = beta-alanine + H(+) + NADH + pyruvate.
47698	beta-alanyl-CoA ammonia-lyase activity	F	Catalysis of the reaction: beta-alanyl-CoA = acryloyl-CoA + NH3.
47699	beta-diketone hydrolase activity	F	Catalysis of the reaction: H(2)O + nonane-4,6-dione = butanoate + H(+) + pentan-2-one.
47700	beta-glucoside kinase activity	F	Catalysis of the reaction: ATP + cellobiose = ADP + 6-phospho-beta-D-glucosyl-(1,4)-D-glucose.
47701	beta-L-arabinosidase activity	F	Catalysis of the reaction: H2O + a beta-L-arabinoside = L-arabinose + an alcohol.
47702	beta-lysine 5,6-aminomutase activity	F	Catalysis of the reaction: (3S)-3,6-diaminohexanoate = (3S,5S)-3,5-diaminohexanoate.
47703	beta-nitroacrylate reductase activity	F	Catalysis of the reaction: 3-nitropropanoate + NADP(+) = 3-nitroacrylate + H(+) + NADPH.
47704	bile-salt sulfotransferase activity	F	Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + taurolithocholate = adenosine 3',5'-bisphosphate + taurolithocholate sulfate.
47705	bilirubin oxidase activity	F	Catalysis of the reaction: 2 bilirubin + O(2) = 2 biliverdin + 2 H(2)O.
47706	biochanin-A reductase activity	F	Catalysis of the reaction: dihydrobiochanin A + NADP(+) = biochanin A + H(+) + NADPH.
47707	biotin-CoA ligase activity	F	Catalysis of the reaction: ATP + biotin + CoA = AMP + diphosphate + biotinyl-CoA.
47708	biotinidase activity	F	Catalysis of the reaction: biotin amide + H2O = biotin + NH3.
47709	bis(2-ethylhexyl)phthalate esterase activity	F	Catalysis of the reaction: bis(2-ethylhexyl)phthalate + H(2)O = 2-ethylhexan-1-ol + 2-ethylhexyl phthalate + H(+).
47710	bis(5'-adenosyl)-triphosphatase activity	F	Catalysis of the reaction: P(1),P(3)-bis(5'-adenosyl) triphosphate + H(2)O = ADP + AMP + 2 H(+).
47711	blasticidin-S deaminase activity	F	Catalysis of the reaction: blasticidin S + H2O = deaminohydroxyblasticidin S + NH3.
47712	Cypridina-luciferin 2-monooxygenase activity	F	Catalysis of the reaction: Cypridina luciferin + O2 = oxidized Cypridina luciferin + CO2 + light.
47713	galactitol 2-dehydrogenase activity	F	Catalysis of the reaction: galactitol + NAD(+) = D-tagatose + H(+) + NADH.
47714	galactolipase activity	F	Catalysis of the reaction: 1,2-diacyl-3-beta-D-galactosyl-sn-glycerol + 2 H2O = 3-beta-D-galactosyl-sn-glycerol + 2 carboxylates.
47715	hypotaurocyamine kinase activity	F	Catalysis of the reaction: ATP + hypotaurocyamine = N(omega)-phosphohypotaurocyamine + ADP + 2 H(+).
47716	imidazole N-acetyltransferase activity	F	Catalysis of the reaction: 1H-imidazole + acetyl-CoA = N-acetylimidazole + CoA.
47717	imidazoleacetate 4-monooxygenase activity	F	Catalysis of the reaction: H(+) + imidazol-4-ylacetate + NADH + O(2) = 5-hydroxyimidazole-4-acetate + H(2)O + NAD(+).
47718	indanol dehydrogenase activity	F	Catalysis of the reaction: indan-1-ol + NAD(P)+ = indanone + NAD(P)H + H+.
47719	indole 2,3-dioxygenase activity	F	Catalysis of the reaction: indole + O(2) = 2-formamidobenzaldehyde.
47720	indoleacetaldoxime dehydratase activity	F	Catalysis of the reaction: (indol-3-yl)acetaldehyde oxime = (indol-3-yl)acetonitrile + H(2)O.
47721	indoleacetate-lysine synthetase activity	F	Catalysis of the reaction: (indol-3-yl)acetate + L-lysine + ATP = N(6)-[(indole-3-yl)acetyl]-L-lysine + ADP + 2 H(+) + phosphate.
47722	indolelactate dehydrogenase activity	F	Catalysis of the reaction: 3-(indol-3-yl)lactate + NAD(+) = 3-(indol-3-yl)pyruvate + H(+) + NADH.
47723	inosinate nucleosidase activity	F	Catalysis of the reaction: H(2)O + IMP = D-ribose 5-phosphate + hypoxanthine.
47724	inosine nucleosidase activity	F	Catalysis of the reaction: inosine + H2O = D-ribose + hypoxanthine.
47725	inulosucrase activity	F	Catalysis of the reaction: sucrose + 2,1-beta-D-fructosyl(n) = glucose + 2,1-beta-D-fructosyl(n+1).
47726	iron-cytochrome-c reductase activity	F	Catalysis of the reaction: ferrocytochrome c + Fe3+ = ferricytochrome c + Fe2+.
47727	isobutyryl-CoA mutase activity	F	Catalysis of the reaction: isobutyryl-CoA = butanoyl-CoA.
47728	carnitine 3-dehydrogenase activity	F	Catalysis of the reaction: carnitine + NAD(+) = 3-dehydrocarnitine + H(+) + NADH.
47729	carnitine decarboxylase activity	F	Catalysis of the reaction: carnitine + H(+) = 2-methylcholine + CO(2).
47730	carnosine synthase activity	F	Catalysis of the reaction: ATP + L-histidine + beta-alanine = AMP + diphosphate + carnosine.
47731	catechol oxidase (dimerizing) activity	F	Catalysis of the reaction: 4 catechol + 3 O2 = 2 dibenzo[1,4]dioxin-2,3-dione + 6 H2O.
47732	CDP-abequose epimerase activity	F	Catalysis of the reaction: CDP-3,6-dideoxy-D-glucose = CDP-3,6-dideoxy-D-mannose.
47733	CDP-glucose 4,6-dehydratase activity	F	Catalysis of the reaction: CDP-D-glucose = CDP-4-dehydro-6-deoxy-D-glucose + H(2)O.
47734	CDP-glycerol diphosphatase activity	F	Catalysis of the reaction: CDP-glycerol + H(2)O = sn-glycerol 3-phosphate + CMP + 2 H(+).
47735	cellobiose dehydrogenase (acceptor) activity	F	Catalysis of the reaction: cellobiose + acceptor = cellobiono-1,5-lactone + reduced acceptor.
47736	cellobiose epimerase activity	F	Catalysis of the reaction: cellobiose = D-glucosyl-D-mannose.
47738	cellobiose phosphorylase activity	F	Catalysis of the reaction: cellobiose + phosphate = alpha-D-glucose 1-phosphate + D-glucose.
47739	cephalosporin-C deacetylase activity	F	Catalysis of the reaction: cephalosporin C + H(2)O = acetate + deacetylcephalosporin C + H(+).
47740	cephalosporin-C transaminase activity	F	Catalysis of the reaction: (7R)-7-(5-carboxylato-5-oxopentanamido)deacetylcephalosporanate + D-glutamate = 2-oxoglutarate + cephalosporin C.
47741	cetraxate benzylesterase activity	F	Catalysis of the reaction: benzyl cetraxate + H(2)O = benzyl alcohol + cetraxate + H(+).
47742	chenodeoxycholoyltaurine hydrolase activity	F	Catalysis of the reaction: chenodeoxycholoyltaurine + H2O = chenodeoxycholate + taurine.
47743	chlordecone reductase activity	F	Catalysis of the reaction: chlordecone alcohol + NADP(+) = chlordecone + H(+) + NADPH.
47744	chloridazon-catechol dioxygenase activity	F	Catalysis of the reaction: 5-amino-4-chloro-2-(2,3-dihydroxyphenyl)pyridazin-3(2H)-one + O(2) = 5-amino-4-chloro-2-(2-hydroxymuconoyl)pyridazin-3(2H)-one + 2 H(+).
47745	chlorogenate hydrolase activity	F	Catalysis of the reaction: chlorogenate + H(2)O = (-)-quinate + cis-caffeate + H(+).
47746	chlorophyllase activity	F	Catalysis of the reaction: chlorophyll + H2O = phytol + chlorophyllide.
47747	cholate-CoA ligase activity	F	Catalysis of the reactions: (1) ATP + cholate + CoA = AMP + diphosphate + choloyl-CoA and (2) ATP + (25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestan-26-oate + CoA = AMP + diphosphate + (25R)-3alpha,7alpha,12alpha-trihydroxy-5beta-cholestanoyl-CoA.
47748	cholestanetetraol 26-dehydrogenase activity	F	Catalysis of the reaction: 5-beta-cholestane-3-alpha,7-alpha,12-alpha,26-tetraol + NAD+ = 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholestan-26-al + NADH.
47749	cholestanetriol 26-monooxygenase activity	F	Catalysis of the reaction: 5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol + NADPH + O2 = 5-beta-cholestane-3-alpha,7-alpha,12-alpha,26-tetraol + NADP+ + H2O.
47750	cholestenol delta-isomerase activity	F	Catalysis of the reaction: 5-alpha-cholest-7-en-3-beta-ol = 5-alpha-cholest-8-en-3-beta-ol.
47751	cholestenone 5-alpha-reductase activity	F	Catalysis of the reaction: 5alpha-cholestan-3-one + NADP(+) = cholest-4-en-3-one + H(+) + NADPH.
47753	choline-sulfatase activity	F	Catalysis of the reaction: choline sulfate + H(2)O = choline + H(+) + sulfate.
47754	choline sulfotransferase activity	F	Catalysis of the reaction: 3'-phospho-5'-adenylyl sulfate + choline = adenosine 3',5'-diphosphate + choline sulfate + H(+).
47755	isocitrate epimerase activity	F	Catalysis of the reaction: D-threo-isocitrate = D-erythro-isocitrate.
47756	chondroitin 4-sulfotransferase activity	F	Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + chondroitin = adenosine 3',5'-bisphosphate + chondroitin 4'-sulfate.
47757	chondroitin-glucuronate 5-epimerase activity	F	Catalysis of the reaction: chondroitin D-glucuronate = dermatan L-iduronate.
47758	ATP:2-methylpropanoate phosphotransferase activity	F	Catalysis of the reaction: 2-methylpropanoate + ATP = 2-methylpropanoyl phosphate + ADP + H(+).
47759	butanal dehydrogenase activity	F	Catalysis of the reaction: butanal + CoA + NAD(P)+ = butanoyl-CoA + NAD(P)H + H+.
47760	butyrate-CoA ligase activity	F	Catalysis of the reaction: ATP + an acid + CoA = AMP + diphosphate + an acyl-CoA.
47761	butyrate kinase activity	F	Catalysis of the reaction: ATP + butanoate = ADP + butanoyl phosphate + H(+).
47762	caffeate 3,4-dioxygenase activity	F	Catalysis of the reaction: trans-caffeate + O(2) = 3-(2-carboxyethenyl)-cis,cis-muconate + 2 H(+).
47763	caffeate O-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + 3,4-dihydroxy-trans-cinnamate = S-adenosyl-L-homocysteine + 3-methoxy-4-hydroxy-trans-cinnamate.
47764	caldesmon kinase activity	F	Catalysis of the reaction: ATP + caldesmon = ADP + caldesmon phosphate.
47765	caldesmon-phosphatase activity	F	Catalysis of the reaction: caldesmon phosphate + H2O = caldesmon + phosphate.
47766	carbamoyl-serine ammonia-lyase activity	F	Catalysis of the reaction: O-carbamoyl-L-serine + H(2)O + H(+) = CO(2) + 2 NH(4)(+) + pyruvate.
47768	carboxy-cis,cis-muconate cyclase activity	F	Catalysis of the reaction: 3-carboxy-2,5-dihydro-5-oxofuran-2-acetate = 3-carboxy-cis,cis-muconate.
47769	arogenate dehydratase activity	F	Catalysis of the reaction: L-arogenate = L-phenylalanine + H2O + CO2.
47770	carboxylate reductase activity	F	Catalysis of the reaction: an aldehyde + acceptor + H2O = a carboxylate + reduced acceptor.
47771	carboxymethylhydantoinase activity	F	Catalysis of the reaction: L-5-carboxymethylhydantoin + H(2)O = N-carbamoyl-L-aspartate + H(+).
47772	carboxymethyloxysuccinate lyase activity	F	Catalysis of the reaction: carboxymethoxysuccinate = fumarate + glycolate.
47773	carnitinamidase activity	F	Catalysis of the reaction: (R)-carnitinamide + H(2)O = (R)-carnitine + NH(4)(+).
47774	cis-2-enoyl-CoA reductase (NADPH) activity	F	Catalysis of the reaction: acyl-CoA + NADP+ = cis-2,3-dehydroacyl-CoA + NADPH.
47775	citramalate CoA-transferase activity	F	Catalysis of the reaction: acetyl-CoA + citramalate = acetate + (3S)-citramalyl-CoA.
47776	citramalate lyase activity	F	Catalysis of the reaction: S-citramalate = acetate + pyruvate.
47777	(3S)-citramalyl-CoA lyase activity	F	Catalysis of the reaction: (3S)-citramalyl-CoA = acetyl-CoA + pyruvate.
47778	[citrate-(pro-3S)-lyase] thiolesterase activity	F	Catalysis of the reaction: [citrate (pro-3S)-lyase](acetyl form) + H2O = [citrate (pro-3S)-lyase](thiol form) + acetate.
47779	citrate-CoA ligase activity	F	Catalysis of the reaction: ATP + citrate + CoA = (3S)-citryl-CoA + ADP + H(+) + phosphate.
47780	citrate dehydratase activity	F	Catalysis of the reaction: citrate = cis-aconitate + H2O.
47781	citrullinase activity	F	Catalysis of the reaction: H2O + citrulline = NH3 + CO2 + L-ornithine.
47782	coniferin beta-glucosidase activity	F	Catalysis of the reaction: H2O + coniferin = D-glucose + coniferol.
47783	corticosterone 18-monooxygenase activity	F	Catalysis of the reaction: corticosterone + reduced adrenal ferredoxin + O2 = 18-hydroxycorticosterone + oxidized adrenal ferredoxin + H2O.
47784	cortisol O-acetyltransferase activity	F	Catalysis of the reaction: acetyl-CoA + cortisol = CoA + cortisol 21-acetate.
47785	cortisol sulfotransferase activity	F	Catalysis of the reaction: 3'-phospho-5'-adenylyl sulfate + cortisol = adenosine 3',5'-diphosphate + cortisol 21-sulfate + H(+).
47786	cortisone alpha-reductase activity	F	Catalysis of the reaction: 4,5alpha-dihydrocortisone + NADP(+) = cortisone + H(+) + NADPH.
47787	delta4-3-oxosteroid 5beta-reductase activity	F	Catalysis of the reactions: (1) 5beta-cholestan-3-one + NADP+ = cholest-4-en-3-one + NADPH + H+ and (2) 17,21-dihydroxy-5beta-pregnane-3,11,20-trione + NADP+ = cortisone + NADPH + H+.
47788	2-coumarate reductase activity	F	Catalysis of the reaction: 3-(2-hydroxyphenyl)propanoate + NAD(+) = trans-2-coumarate + H(+) + NADH.
47789	creatininase activity	F	Catalysis of the reaction: creatinine + H(2)O = creatine.
47790	creatinine deaminase activity	F	Catalysis of the reaction: creatinine + H2O = N-methylhydantoin + NH3.
47791	cucurbitacin delta23-reductase activity	F	Catalysis of the reaction: 23,24-dihydrocucurbitacin + NAD(P)+ = cucurbitacin + NAD(P)H + H+.
47792	cyanohydrin beta-glucosyltransferase activity	F	Catalysis of the reaction: UDP-glucose + (S)-4-hydroxymandelonitrile = UDP + (S)-4-hydroxy-mandelonitrile beta-D-glucoside.
47793	cycloeucalenol cycloisomerase activity	F	Catalysis of the reaction: cycloeucalenol = obtusifoliol.
47794	cyclohexadienyl dehydrogenase activity	F	Catalysis of the reaction: L-arogenate + NAD+ = L-tyrosine + NADH + CO2.
47795	cyclohexane-1,2-diol dehydrogenase activity	F	Catalysis of the reaction: trans-cyclohexane-1,2-diol + NAD+ = 2-hydroxycyclohexan-1-one + NADH.
47796	cyclohexane-1,3-dione hydrolase activity	F	Catalysis of the reaction: cyclohexane-1,3-dione + H(2)O = 5-oxohexanoate + H(+).
47797	cyclohexanone dehydrogenase activity	F	Catalysis of the reaction: A + cyclohexanone = AH(2) + cyclohex-2-enone.
47798	cyclomaltodextrinase activity	F	Catalysis of the reaction: H2O + cyclomaltodextrin = linear maltodextrin.
47799	cyclopentanone monooxygenase activity	F	Catalysis of the reaction: cyclopentanone + H(+) + NADPH + O(2) = 5-valerolactone + H(2)O + NADP(+).
47800	cysteamine dioxygenase activity	F	Catalysis of the reaction: cysteamine + O(2) = H(+) + hypotaurine.
47801	L-cysteine:2-oxoglutarate aminotransferase activity	F	Catalysis of the reaction: L-cysteine + 2-oxoglutarate = mercaptopyruvate + L-glutamate.
47802	cysteine-conjugate transaminase activity	F	Catalysis of the reaction: 2-oxoglutarate + S-(4-bromophenyl)-L-cysteine = (4-bromophenylsulfanyl)pyruvate + L-glutamate.
47803	cysteine lyase activity	F	Catalysis of the reaction: L-cysteine + sulfite = L-cysteate + sulfide.
47804	cysteine-S-conjugate beta-lyase activity	F	Catalysis of the reaction: RS-CH2-CH(NH3+)COO- = RSH + NH3 + pyruvate.
47805	cytidylate cyclase activity	F	Catalysis of the reaction: CTP = 3',5'-cyclic CMP + diphosphate + H(+).
47806	cytochrome-c3 hydrogenase activity	F	Catalysis of the reaction: 2 H2 + ferricytochrome c3 = 4 H+ + ferrocytochrome c3.
47807	cytokinin 7-beta-glucosyltransferase activity	F	Catalysis of the reaction: 6-alkylaminopurine + UDP-D-glucose = 6-alkylamino-7-beta-D-glucosylpurine + H+ + UDP. This reaction is an N-glucosylation event.
47808	D(-)-tartrate dehydratase activity	F	Catalysis of the reaction: D-tartrate = H(2)O + oxaloacetate.
47809	D-2-hydroxy-acid dehydrogenase activity	F	Catalysis of the reaction: (R)-lactate + A = AH(2) + pyruvate.
47810	D-alanine:2-oxoglutarate aminotransferase activity	F	Catalysis of the reaction: D-alanine + 2-oxoglutarate = pyruvate + D-glutamate.
47811	D-alanine gamma-glutamyltransferase activity	F	Catalysis of the reaction: D-alanine + L-glutamine = gamma-L-glutamyl-D-alanine + NH(4)(+).
47812	D-amino-acid N-acetyltransferase activity	F	Catalysis of the reaction: acetyl-CoA + a D-amino acid = CoA + an N-acetyl-D-amino-acid.
47813	D-arabinitol 4-dehydrogenase activity	F	Catalysis of the reaction: D-arabinitol + NAD+ = D-xylulose + NADH.
47814	D-arabinokinase activity	F	Catalysis of the reaction: D-arabinose + ATP = D-arabinose 5-phosphate + ADP.
47815	D-arabinonolactonase activity	F	Catalysis of the reaction: D-arabinono-1,4-lactone + H(2)O = D-arabinonate + H(+).
47816	D-arabinose 1-dehydrogenase (NAD) activity	F	Catalysis of the reaction: D-arabinose + NAD+ = D-arabinono-1,4-lactone + NADH.
47817	D-arginase activity	F	Catalysis of the reaction: D-arginine + H(2)O = D-ornithine + urea.
47818	D-fuconate dehydratase activity	F	Catalysis of the reaction: D-fuconate = 2-dehydro-3-deoxy-D-fuconate + H(2)O.
47819	D-glutamate(D-aspartate) oxidase activity	F	Catalysis of the reaction: D-glutamate + H2O + O2 = 2-oxoglutarate + NH3 + H2O2, and D-aspartate + H2O + O2 = oxaloacetate + NH3 + H2O2.
47820	D-glutamate cyclase activity	F	Catalysis of the reaction: D-glutamate = 5-oxo-D-proline + H(2)O.
47821	D-glutamate oxidase activity	F	Catalysis of the reaction: D-glutamate + H2O + O2 = 2-oxoglutarate + NH3 + H2O2.
47822	hypotaurine dehydrogenase activity	F	Catalysis of the reaction: H(2)O + hypotaurine + NAD(+) = H(+) + NADH + taurine.
47823	D-glutamyltransferase activity	F	Catalysis of the reaction: L(or D)-glutamine + D-glutamyl-peptide = NH3 + 5-glutamyl-D-glutamyl-peptide.
47824	D-iditol 2-dehydrogenase activity	F	Catalysis of the reaction: D-iditol + NAD+ = D-sorbose + NADH.
47825	D-lactate-2-sulfatase activity	F	Catalysis of the reaction: (R)-2-O-sulfolactate + H(2)O = (R)-lactate + H(+) + sulfate.
47826	D-lysine 5,6-aminomutase activity	F	Catalysis of the reaction: D-lysine = 2,5-diaminohexanoate.
47827	D-lysopine dehydrogenase activity	F	Catalysis of the reaction: D-lysopine + H(2)O + NADP(+) = L-lysine + H(+) + NADPH + pyruvate.
47828	D-lyxose ketol-isomerase activity	F	Catalysis of the reaction: D-lyxose = D-xylulose.
47829	D-nopaline dehydrogenase activity	F	Catalysis of the reaction: N2-(D-1,3-dicarboxypropyl)-L-arginine + NADP+ + H2O = L-arginine + 2-oxoglutarate + NADPH.
47830	D-octopine dehydrogenase activity	F	Catalysis of the reaction: N2-(D-1-carboxyethyl)-L-arginine + NAD+ + H2O = L-arginine + pyruvate + NADH.
47831	D-ornithine 4,5-aminomutase activity	F	Catalysis of the reaction: D-ornithine = (2R,4S)-2,4-diaminopentanoate.
47832	D-pinitol dehydrogenase activity	F	Catalysis of the reaction: 5D-5-O-methyl-chiro-inositol + NADP(+) = 2D-5-O-methyl-2,3,5/4,6-pentahydroxycyclohexanone + H(+) + NADPH.
47833	D-sorbitol dehydrogenase (acceptor) activity	F	Catalysis of the reaction: D-sorbitol + acceptor = L-sorbose + reduced acceptor.
47834	D-threo-aldose 1-dehydrogenase activity	F	Catalysis of the reaction: a D-threo-aldose + NAD+ = a D-threo-aldono-1,5-lactone + NADH.
47835	D-tryptophan N-acetyltransferase activity	F	Catalysis of the reaction: D-tryptophan + acetyl-CoA = N-acetyl-D-tryptophan + CoA + H(+).
47836	D-tryptophan N-malonyltransferase activity	F	Catalysis of the reaction: D-tryptophan + malonyl-CoA = N(2)-malonyl-D-tryptophan + CoA + H(+).
47837	D-xylose 1-dehydrogenase (NADP+) activity	F	Catalysis of the reaction: D-xylose + NADP(+) = D-xylono-1,5-lactone + H(+) + NADPH.
47838	D-xylose 1-dehydrogenase (NAD) activity	F	Catalysis of the reaction: D-xylose + NAD+ = D-xylonolactone + NADH.
47839	dATP(dGTP)-DNA purinetransferase activity	F	Catalysis of the reaction: dATP + depurinated DNA = ribose triphosphate + DNA.
47840	dCTP diphosphatase activity	F	Catalysis of the reaction: dCTP + H2O = dCMP + diphosphate.
47841	dehydrogluconokinase activity	F	Catalysis of the reaction: 2-dehydro-D-gluconate + ATP = 6-phospho-2-dehydro-D-gluconate + ADP + 2 H(+).
47842	dehydro-L-gulonate decarboxylase activity	F	Catalysis of the reaction: 3-dehydro-L-gulonate + H(+) = L-xylulose + CO(2).
47843	dehydrogluconate dehydrogenase activity	F	Catalysis of the reaction: 2-dehydro-D-gluconate + A = 2,5-didehydro-D-gluconate + AH(2).
47844	deoxycytidine deaminase activity	F	Catalysis of the reaction: deoxycytidine + H2O = deoxyuridine + NH3.
47845	deoxylimonate A-ring-lactonase activity	F	Catalysis of the reaction: deoxylimonoate + H(2)O = deoxylimononate D-ring-lactone + H(+).
47846	deoxynucleotide 3'-phosphatase activity	F	Catalysis of the reaction: a deoxynucleoside 3'-phosphate + H2O = a deoxynucleoside + phosphate.
47847	deoxyuridine phosphorylase activity	F	Catalysis of the reaction: deoxyuridine + phosphate = uracil + deoxy-D-ribose 1-phosphate.
47848	dephospho-[reductase kinase] kinase activity	F	Catalysis of the reaction: ATP + dephospho-[[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase] = ADP + [[hydroxymethylglutaryl-CoA reductase (NADPH)] kinase].
47849	dextransucrase activity	F	Catalysis of the reaction: sucrose + 1,6-alpha-D-glucosyl(n) = D-fructose + 1,6-alpha-D-glucosyl(n+1).
47850	diaminopimelate dehydrogenase activity	F	Catalysis of the reaction: meso-2,6-diaminopimelate + H(2)O + NADP(+) = L-2-amino-6-oxopimelate + H(+) + NADPH + NH(4)(+).
47851	dicarboxylate-CoA ligase activity	F	Catalysis of the reaction: ATP + an omega-dicarboxylic acid = AMP + diphosphate + an omega-carboxyacyl-CoA.
47852	diferric-transferrin reductase activity	F	Catalysis of the reaction: transferrin[Fe2+]2 + NAD+ = transferrin[Fe3+]2 + NADH.
47853	difructose-anhydride synthase activity	F	Catalysis of the reaction: H2O + bis-D-fructose 2',1:2,1'-dianhydride = inulobiose.
47854	diguanidinobutanase activity	F	Catalysis of the reaction: 1,4-diguanidinobutane + H(2)O = agmatine + urea.
47855	dihydrobunolol dehydrogenase activity	F	Catalysis of the reaction: dihydrobunolol + NADP(+) = bunolol + H(+) + NADPH.
47856	dihydrocoumarin hydrolase activity	F	Catalysis of the reaction: 3,4-dihydrocoumarin + H(2)O = 3-(2-hydroxyphenyl)propanoate + H(+).
47857	dihydrouracil oxidase activity	F	Catalysis of the reaction: 5,6-dihydrouracil + O(2) = H(2)O(2) + uracil.
47858	dihydroxyfumarate decarboxylase activity	F	Catalysis of the reaction: dihydroxyfumarate + H(+) = 2-hydroxy-3-oxopropanoate + CO(2).
47860	diiodophenylpyruvate reductase activity	F	Catalysis of the reaction: 3-(3,5-diiodo-4-hydroxyphenyl)lactate + NAD(+) = 3-(3,5-diiodo-4-hydroxyphenyl)pyruvate + H(+) + NADH.
47861	diiodotyrosine transaminase activity	F	Catalysis of the reaction: 2-oxoglutarate + 3,5-diiodo-L-tyrosine = 3-(3,5-diiodo-4-hydroxyphenyl)pyruvate + L-glutamate.
47862	diisopropyl-fluorophosphatase activity	F	Catalysis of the reaction: diisopropyl fluorophosphate + H(2)O = diisopropyl phosphate + 2 H(+) + hydrogen fluoride.
47863	dimethylallylcistransferase activity	F	Catalysis of the reaction: dimethylallyl diphosphate + isopentenyl diphosphate = diphosphate + neryl diphosphate.
47864	dimethylaniline-N-oxide aldolase activity	F	Catalysis of the reaction: N,N-dimethylaniline N-oxide = N-methylaniline + formaldehyde.
47865	dimethylglycine dehydrogenase activity	F	Catalysis of the reaction: N,N-dimethylglycine + electron-transfer flavoprotein + H2O = sarcosine + formaldehyde + reduced electron-transfer flavoprotein.
47866	dimethylglycine oxidase activity	F	Catalysis of the reaction: N,N-dimethylglycine + H(2)O + O(2) = formaldehyde + H(2)O(2) + sarcosine.
47867	dimethylmalate dehydrogenase activity	F	Catalysis of the reaction: (R)-3,3-dimethylmalate + NAD(+) = 3-methyl-2-oxobutanoate + CO(2) + NADH.
47868	dimethylmaleate hydratase activity	F	Catalysis of the reaction: (2R,3S)-2,3-dimethylmalate = dimethylmaleate + H(2)O.
47869	dimethylpropiothetin dethiomethylase activity	F	Catalysis of the reaction: S,S-dimethyl-beta-propiothetin = acrylate + dimethyl sulfide + H(+).
47870	discadenine synthase activity	F	Catalysis of the reaction: N(6)-dimethylallyladenine + S-adenosyl-L-methionine(1+) = S-methyl-5'-thioadenosine + discadenine + H(+).
47871	disulfoglucosamine-6-sulfatase activity	F	Catalysis of the reaction: N(2),6-disulfo-D-glucosamine + H(2)O = N-sulfo-D-glucosamine + H(+) + sulfate.
47872	dolichol O-acyltransferase activity	F	Catalysis of the reaction: palmitoyl-CoA + dolichol = CoA + dolichyl palmitate.
47873	dolichyl-phosphatase activity	F	Catalysis of the reaction: dolichyl phosphate + H2O = dolichol + phosphate.
47874	dolichyldiphosphatase activity	F	Catalysis of the reaction: dolichyl diphosphate + H2O = dolichyl phosphate + phosphate.
47875	ecdysone oxidase activity	F	Catalysis of the reaction: Ecdysone + O(2) = 3-dehydroecdysone + H(2)O(2).
47876	endoglycosylceramidase activity	F	Catalysis of the reaction: H2O + oligoglycosylglucosylceramide = ceramide + oligoglycosylglucose.
47877	ephedrine dehydrogenase activity	F	Catalysis of the reaction: (1R,2S)-ephedrine + NAD(+) = (R)-2-methylimino-1-phenylpropan-1-ol + 2 H(+) + NADH.
47878	erythritol kinase activity	F	Catalysis of the reaction: ATP + erythritol = D-erythritol 4-phosphate + ADP + 2 H(+).
47879	erythronolide synthase activity	F	Catalysis of the reaction: 6 malonyl-CoA + propionyl-CoA = 7 CoA + 6-deoxyerythronolide B.
47880	erythrulose reductase activity	F	Catalysis of the reaction: D-threitol + NADP(+) = D-erythrulose + H(+) + NADPH.
47881	estradiol 17-alpha-dehydrogenase activity	F	Catalysis of the reaction: estradiol-17-alpha + NAD(P)+ = estrone + NAD(P)H + H+.
47882	estradiol 6-beta-monooxygenase activity	F	Catalysis of the reaction: AH(2) + estradiol-17beta + O(2) = 6beta-hydroxyestradiol-17beta + A + H(2)O.
47883	ethanolamine oxidase activity	F	Catalysis of the reaction: ethanolamine + H2O + O2 = glycolaldehyde + NH3 + H2O2.
47884	FAD diphosphatase activity	F	Catalysis of the reaction: FAD + H2O = AMP + FMN.
47885	farnesol 2-isomerase activity	F	Catalysis of the reaction: 2-trans,6-trans-farnesol = 2-cis,6-trans-farnesol.
47886	farnesol dehydrogenase activity	F	Catalysis of the reaction: 2-trans,6-trans-farnesol + NADP(+) = 2-trans,6-trans-farnesal + H(+) + NADPH.
47887	farnesyl diphosphate kinase activity	F	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate + ATP = 2-trans,6-trans-farnesyl triphosphate + ADP.
47888	fatty acid peroxidase activity	F	Catalysis of the reaction: 2 H(2)O(2) + H(+) + palmitate = CO(2) + 3 H(2)O + pentadecanal.
47889	ferredoxin-nitrate reductase activity	F	Catalysis of the reaction: nitrite + H2O + 2 oxidized ferredoxin = nitrate + 2 reduced ferredoxin.
47890	flavanone 4-reductase activity	F	Catalysis of the reaction: (2S)-flavan-4-ol + NADP+ = (2S)-flavanone + NADPH.
47891	flavone 7-O-beta-glucosyltransferase activity	F	Catalysis of the reaction: UDP-glucose + 5,7,3',4'-tetrahydroxyflavone = UDP + 7-O-beta-D-glucosyl-5,7,3',4'-tetrahydroxyflavone.
47892	flavone apiosyltransferase activity	F	Catalysis of the reaction: UDP-apiose + 7-O-beta-D-glucosyl-5,7,4'-trihydroxyflavone = UDP + 7-O-(beta-D-apiofuranosyl-1,2-beta-D-glucosyl)-5,7,4'-trihydroxyflavone.
47893	flavonol 3-O-glucosyltransferase activity	F	Catalysis of the reaction: UDP-glucose + a flavonol = UDP + a flavonol 3-O-D-glucoside.
47894	flavonol 3-sulfotransferase activity	F	Catalysis of the reaction: 3'-phospho-5'-adenylyl sulfate + quercetin = adenosine 3',5'-diphosphate + H(+) + quercetin 3-sulfate.
47895	formaldehyde dismutase activity	F	Catalysis of the reaction: 2 formaldehyde + H2O = methanol + formate.
47896	formaldehyde transketolase activity	F	Catalysis of the reaction: D-xylulose 5-phosphate + formaldehyde = glyceraldehyde 3-phosphate + glycerone.
47897	formate-dihydrofolate ligase activity	F	Catalysis of the reaction: 7,8-dihydrofolate + ATP + formate = 10-formyldihydrofolate + ADP + H(+) + phosphate.
47898	formate dehydrogenase (cytochrome) activity	F	Catalysis of the reaction: formate + ferricytochrome b1 = CO2 + ferrocytochrome b1.
47899	formate dehydrogenase (NADP+) activity	F	Catalysis of the reaction: formate + NADP(+) = CO(2) + NADPH.
47900	formate kinase activity	F	Catalysis of the reaction: ATP + formate = ADP + formyl phosphate + H(+).
47901	formyl-CoA hydrolase activity	F	Catalysis of the reaction: formyl-CoA + H(2)O = CoA + formate + H(+).
47902	formylaspartate deformylase activity	F	Catalysis of the reaction: N-formyl-L-aspartate + H2O = formate + L-aspartate.
47903	fructose 5-dehydrogenase (NADP+) activity	F	Catalysis of the reaction: D-fructose + NADP+ = 5-dehydro-D-fructose + NADPH.
47904	fructose 5-dehydrogenase activity	F	Catalysis of the reaction: D-fructose + A = 5-dehydro-D-fructose + AH(2).
47905	fructose-6-phosphate phosphoketolase activity	F	Catalysis of the reaction: D-fructose 6-phosphate + phosphate = acetyl phosphate + D-erythrose 4-phosphate + H2O.
47906	fucosterol-epoxide lyase activity	F	Catalysis of the reaction: (24R,24'R)-fucosterol epoxide = acetaldehyde + desmosterol.
47907	furylfuramide isomerase activity	F	Catalysis of the reaction: (E)-2-(2-furyl)-3-(5-nitro-2-furyl)acrylamide = (Z)-2-(2-furyl)-3-(5-nitro-2-furyl)acrylamide.
47908	fusarinine-C ornithinesterase activity	F	Catalysis of the reaction: N5-acyl-L-ornithine ester + H2O = N5-acyl-L-ornithine + an alcohol.
47909	galactolipid O-acyltransferase activity	F	Catalysis of the reaction: 2 mono-beta-D-galactosyldiacylglycerol = acylmono-beta-D-galactosyl-diacylglycerol + mono-beta-D-galactosylacylglycerol.
47910	galactose 1-dehydrogenase (NADP+) activity	F	Catalysis of the reaction: D-galactose + NADP+ = D-galactonolactone + NADPH.
47911	galacturan 1,4-alpha-galacturonidase activity	F	Catalysis of the reaction: [(1->4)-alpha-D-galacturonide](n) + H2O = [(1->4)-alpha-D-galacturonide](n-1) + D-galacturonate.
47912	galacturonokinase activity	F	Catalysis of the reaction: alpha-D-galacturonate + ATP = 1-phospho-alpha-D-galacturonate + ADP + 2 H(+).
47913	gallate 1-beta-glucosyltransferase activity	F	Catalysis of the reaction: gallate + UDP-D-glucose = 1-O-galloyl-beta-D-glucose + UDP.
47914	gamma-glutamylhistamine synthase activity	F	Catalysis of the reaction: histamine + L-glutamate + ATP = N(alpha)-gamma-L-glutamylhistamine + products of ATP breakdown.
47915	ganglioside galactosyltransferase activity	F	Catalysis of the reaction: UDP-galactose + N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-1,4-beta-D-glucosyl-N-acylsphingosine = UDP + D-galactosyl-1,3-beta-N-acetyl-D-galactosaminyl-(N-acetylneuraminyl)-D-galactosyl-D-glucosyl-N-acylsphingosine.
47916	GDP-6-deoxy-D-talose 4-dehydrogenase activity	F	Catalysis of the reaction: GDP-6-deoxy-D-talose + NAD(P)+ = GDP-4-dehydro-6-deoxy-D-talose + NAD(P)H + H+.
47917	GDP-glucosidase activity	F	Catalysis of the reaction: GDP-D-glucose + H(2)O = D-glucose + GDP + H(+).
47918	GDP-mannose 3,5-epimerase activity	F	Catalysis of the reaction: GDP-mannose = GDP-L-galactose.
47919	GDP-mannose 6-dehydrogenase activity	F	Catalysis of the reaction: GDP-alpha-D-mannose + H(2)O + 2 NAD(+) = GDP-D-mannuronate + 3 H(+) + 2 NADH.
47920	geissoschizine dehydrogenase activity	F	Catalysis of the reaction: geissoschizine + NADP(+) = 4,21-dehydrogeissoschizine + H(+) + NADPH.
47921	aminoglycoside 2'-N-acetyltransferase activity	F	Catalysis of the reaction: acetyl-CoA + gentamicin C(1a) = N(2')-acetylgentamicin C(1a) + CoA + H(+). This is acetylation of the 2'-amino group of the 6-deoxy-6-aminoglucose ring.
47922	gentisate 1,2-dioxygenase activity	F	Catalysis of the reaction: 2,5-dihydroxybenzoate + O(2) = 3-maleylpyruvate + H(+).
47923	gentisate decarboxylase activity	F	Catalysis of the reaction: 2,5-dihydroxybenzoate + H(+) = CO(2) + hydroquinone.
47924	geraniol dehydrogenase activity	F	Catalysis of the reaction: geraniol + NADP+ = geranial + NADPH.
47925	geranoyl-CoA carboxylase activity	F	Catalysis of the reaction: ATP + bicarbonate + geranoyl-CoA = 3-(4-methylpent-3-en-1-yl)pent-2-enedioyl-CoA + ADP + 2 H(+) + phosphate.
47926	geranyl-diphosphate cyclase activity	F	Catalysis of the reaction: geranyl diphosphate = (2S)-bornyl diphosphate.
47927	gibberellin-44 dioxygenase activity	F	Catalysis of the reaction: gibberellin 44 + 2-oxoglutarate + O2 = gibberellin 19 + succinate + CO2.
47928	gibberellin beta-D-glucosyltransferase activity	F	Catalysis of the reaction: UDP-glucose + gibberellin = UDP + gibberellin 2-O-beta-D-glucoside.
47929	gluconate dehydratase activity	F	Catalysis of the reaction: D-gluconate = 2-dehydro-3-deoxy-D-gluconate + H(2)O.
47930	glucosaminate ammonia-lyase activity	F	Catalysis of the reaction: D-glucosaminate = 2-dehydro-3-deoxy-D-gluconate + NH3.
47931	glucosamine kinase activity	F	Catalysis of the reaction: ATP + D-glucosamine = ADP + D-glucosamine phosphate.
47932	glucosamine N-acetyltransferase activity	F	Catalysis of the reaction: D-glucosamine + acetyl-CoA = N-acetyl-D-glucosamine + CoA + H(+).
47933	glucose-1,6-bisphosphate synthase activity	F	Catalysis of the reaction: 3-phospho-D-glyceroyl phosphate + alpha-D-glucose 1-phosphate = 3-phospho-D-glycerate + alpha-D-glucose 1,6-bisphosphate + H(+).
47934	glucose 1-dehydrogenase (NAD+) activity	F	Catalysis of the reaction: D-glucose + NAD+ = D-glucono-1,5-lactone + NADH.
47935	glucose 1-dehydrogenase (NADP+) activity	F	Catalysis of the reaction: D-glucose + NADP+ = D-glucono-1,4-lactone + NADPH.
47936	glucose 1-dehydrogenase [NAD(P)] activity	F	Catalysis of the reaction: beta-D-glucose + NAD(P)+ = D-glucono-1,5-lactone + NAD(P)H.
47937	glucose-1-phosphate phosphodismutase activity	F	Catalysis of the reaction: 2 D-glucose 1-phosphate = D-glucose + D-glucose 1,6-bisphosphate.
47938	glucose-6-phosphate 1-epimerase activity	F	Catalysis of the reaction: alpha-D-glucose 6-phosphate = beta-D-glucose 6-phosphate.
47939	L-glucuronate reductase activity	F	Catalysis of the reaction: L-gulonate + NADP(+) = D-glucuronate + H(+) + NADPH.
47940	glucuronokinase activity	F	Catalysis of the reaction: D-glucuronate + ATP = 1-phospho-alpha-D-glucuronate + ADP + 2 H(+).
47941	glucuronolactone reductase activity	F	Catalysis of the reaction: L-gulono-1,4-lactone + NADP(+) = D-glucurono-3,6-lactone + H(+) + NADPH.
47942	glutamate-ethylamine ligase activity	F	Catalysis of the reaction: L-glutamate + ATP + ethylamine = N(5)-ethyl-L-glutamine + ADP + 2 H(+) + phosphate.
47943	glutamate-methylamine ligase activity	F	Catalysis of the reaction: L-glutamate + ATP + methylammonium = N(5)-methyl-L-glutamine + ADP + 2 H(+) + phosphate.
47944	glutamate 1-kinase activity	F	Catalysis of the reaction: L-glutamate + ATP = alpha-L-glutamyl phosphate + ADP + H(+).
47945	L-glutamine:pyruvate aminotransferase activity	F	Catalysis of the reaction: L-glutamine + pyruvate = 2-oxoglutaramate + L-alanine.
47946	glutamine N-acyltransferase activity	F	Catalysis of the reaction: acyl-CoA + L-glutamine = CoA + N-acyl-L-glutamine.
47947	glutamine N-phenylacetyltransferase activity	F	Catalysis of the reaction: phenylacetyl-CoA + L-glutamine = CoA + alpha-N-phenylacetyl-L-glutamine.
47948	glutarate-CoA ligase activity	F	Catalysis of the reaction: ATP + CoA + glutarate = ADP + glutaryl-CoA + H(+) + phosphate.
47949	glutarate-semialdehyde dehydrogenase activity	F	Catalysis of the reaction: glutarate semialdehyde + NAD+ + H2O = glutarate + NADH.
47950	glutathione oxidase activity	F	Catalysis of the reaction: 2 glutathione + O(2) = glutathione disulfide + H(2)O(2).
47951	glutathione thiolesterase activity	F	Catalysis of the reaction: S-acylglutathione + H(2)O = a carboxylate + glutathione + H(+).
47952	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity	F	Catalysis of the reaction: sn-glycerol 3-phosphate + NAD(P)+ = glycerone phosphate + NAD(P)H + H+.
47953	glycerol 2-dehydrogenase (NADP+) activity	F	Catalysis of the reaction: glycerol + NADP(+) = glycerone + H(+) + NADPH.
47954	glycerol-2-phosphatase activity	F	Catalysis of the reaction: glycerol 2-phosphate + H(2)O = glycerol + phosphate.
47955	glycerol dehydrogenase (acceptor) activity	F	Catalysis of the reaction: A + glycerol = AH(2) + glycerone.
47956	glycerol dehydrogenase [NADP+] activity	F	Catalysis of the reaction: glycerol + NADP+ = D-glyceraldehyde + NADPH.
47957	4'-methoxyisoflavone 2'-hydroxylase activity	F	Catalysis of the reaction: formononetin + NADPH + O2 = 2'-hydroxyformononetin + NADP+ + H2O.
47958	glycine:2-oxoglutarate aminotransferase activity	F	Catalysis of the reaction: glycine + 2-oxoglutarate = glyoxylate + L-glutamate.
47959	glycine dehydrogenase (cytochrome) activity	F	Catalysis of the reaction: glycine + H2O + 2 ferricytochrome c = glyoxylate + NH3 + 2 ferrocytochrome c.
47960	glycine dehydrogenase activity	F	Catalysis of the reaction: glycine + H2O + NAD+ = glyoxylate + NH3 + NADH.
47961	glycine N-acyltransferase activity	F	Catalysis of the reaction: acyl-CoA + glycine = CoA + N-acylglycine.
47962	glycine N-benzoyltransferase activity	F	Catalysis of the reaction: benzoyl-CoA + glycine = N-benzoylglycine + CoA + H(+).
47963	glycine N-choloyltransferase activity	F	Catalysis of the reaction: choloyl-CoA + glycine = CoA + glycocholate.
47964	glyoxylate reductase activity	F	Catalysis of the reaction: glycolate + NAD+ = glyoxylate + NADH.
47965	glycoprotein O-fatty-acyltransferase activity	F	Catalysis of the reaction: palmitoyl-CoA + mucus glycoprotein = CoA + O-palmitoylglycoprotein.
47966	glycosulfatase activity	F	Catalysis of the reaction: D-glucose 6-sulfate + H(2)O = D-glucose + H(+) + sulfate.
47967	glycyrrhizinate beta-glucuronidase activity	F	Catalysis of the reaction: glycyrrhizate + H(2)O = 2-(beta-D-glucuronosyl)-D-glucuronate + glycyrrhetinate.
47968	glyoxylate dehydrogenase (acylating) activity	F	Catalysis of the reaction: CoA + glyoxylate + NADP(+) = H(+) + NADPH + oxalyl-CoA.
47969	glyoxylate oxidase activity	F	Catalysis of the reaction: glyoxylate + H(2)O + O(2) = H(2)O(2) + H(+) + oxalate.
47970	guanidinoacetase activity	F	Catalysis of the reaction: guanidinoacetate + H(2)O = glycine + urea.
47971	guanidinobutyrase activity	F	Catalysis of the reaction: 4-guanidinobutanoate + H(2)O = 4-aminobutanoate + urea.
47972	guanidinopropionase activity	F	Catalysis of the reaction: 3-guanidinopropanoate + H(2)O = beta-alanine + urea.
47973	guanidinoacetate kinase activity	F	Catalysis of the reaction: ATP + guanidinoacetate = ADP + 2 H(+) + phosphoguanidinoacetate.
47974	guanosine deaminase activity	F	Catalysis of the reaction: guanosine + H2O = xanthosine + NH3.
47975	guanosine phosphorylase activity	F	Catalysis of the reaction: guanosine + phosphate = guanine + D-ribose 1-phosphate.
47976	hamamelose kinase activity	F	Catalysis of the reaction: D-hamamelose + ATP = D-hamamelose 2'-phosphate + ADP + 2 H(+).
47977	hepoxilin-epoxide hydrolase activity	F	Catalysis of the reaction: (5Z,9E,14Z)-(8x,11R,12S)-11,12-epoxy-8-hydroxyicosa-5,9,14-trienoate + H2O = (5Z,9E,14Z)-(8x,11x,12S)-8,11,12-trihydroxyicosa-5,9,14-trienoate.
47978	hexadecanol dehydrogenase activity	F	Catalysis of the reaction: hexadecanol + NAD+ = hexadecanal + NADH.
47979	hexose oxidase activity	F	Catalysis of the reaction: hexose + O2 = aldono-1,5-lactone + H202.
47980	hippurate hydrolase activity	F	Catalysis of the reaction: N-benzoylglycine + H(2)O = benzoate + glycine.
47981	histidine N-acetyltransferase activity	F	Catalysis of the reaction: L-histidine + acetyl-CoA = N(alpha)-acetyl-L-histidine + CoA + H(+).
47982	homocysteine desulfhydrase activity	F	Catalysis of the reaction: L-homocysteine + H2O = sulfide + NH3 + 2-oxobutanoate.
47983	homoglutathione synthase activity	F	Catalysis of the reaction: beta-alanine + L-gamma-glutamyl-L-cysteine + ATP = gamma-L-glutamyl-L-cysteinyl-beta-alanine + ADP + 2 H(+) + phosphate.
47985	hydrogen dehydrogenase activity	F	Catalysis of the reaction: H2 + NAD+ = H+ + NADH.
47986	hydrogen-sulfide S-acetyltransferase activity	F	Catalysis of the reaction: acetyl-CoA + S(2-) = CoA + thioacetate.
47987	hydroperoxide dehydratase activity	F	Catalysis of the reaction: (9Z,11E,14Z)-(13S)-hydroperoxyoctadeca-9,11,14-trienoate = (9Z)-(13S)-12,13-epoxyoctadeca-9,11-dienoate + H2O.
47988	hydroxyacid-oxoacid transhydrogenase activity	F	Catalysis of the reaction: (S)-3-hydroxybutanoate + 2-oxoglutarate = acetoacetate + (R)-2-hydroxyglutarate.
47989	hydroxybutyrate-dimer hydrolase activity	F	Catalysis of the reaction: (R)-3-[(R)-3-hydroxybutanoyloxy]butanoate + H(2)O = 2 (R)-3-hydroxybutanoate + H(+).
47990	hydroxyglutamate decarboxylase activity	F	Catalysis of the reaction: 3-hydroxy-L-glutamate + H(+) = 4-amino-3-hydroxybutanoate + CO(2).
47991	hydroxylamine oxidase activity	F	Catalysis of the reaction: hydroxylamine + O(2) = H(2)O + H(+) + nitrite.
47992	hydroxylysine kinase activity	F	Catalysis of the reaction: erythro-5-hydroxy-L-lysine + GTP = 5-phosphonooxy-L-lysine + GDP + 2 H(+).
47993	hydroxymalonate dehydrogenase activity	F	Catalysis of the reaction: hydroxymalonate + NAD(+) = H(+) + NADH + oxomalonate.
47994	hydroxymethylglutaryl-CoA hydrolase activity	F	Catalysis of the reaction: (S)-3-hydroxy-3-methylglutaryl-CoA + H(2)O = 3-hydroxy-3-methylglutarate + CoA + H(+).
47995	hydroxyphenylpyruvate reductase activity	F	Catalysis of the reaction: 3-(4-hydroxyphenyl)lactate + NAD+ = 3-(4-hydroxyphenyl)pyruvate + NADH.
47996	hydroxyphytanate oxidase activity	F	Catalysis of the reaction: (2S)-2-hydroxyphytanate + O(2) = 2-oxophytanate + H(2)O(2).
47997	hydroxypyruvate decarboxylase activity	F	Catalysis of the reaction: 3-hydroxypyruvate + H(+) = CO(2) + glycolaldehyde.
47998	hyoscyamine (6S)-dioxygenase activity	F	Catalysis of the reaction: 2-oxoglutarate + L-hyoscyamine + O(2) = (6S)-6-hydroxyhyoscyamine + CO(2) + succinate.
47999	hyponitrite reductase activity	F	Catalysis of the reaction: 2 hydroxylamine + 2 NAD(+) = 2 H(+) + hyponitrous acid + 2 NADH.
48000	isoflavone 3'-hydroxylase activity	F	Catalysis of the reaction: formononetin + NADPH + O2 = calycosin + NADP+ + H2O.
48001	erythrose-4-phosphate dehydrogenase activity	F	Catalysis of the reaction: D-erythrose 4-phosphate + H(2)O + NAD(+) = 4-phospho-D-erythronate + 2 H(+) + NADH.
48002	antigen processing and presentation of peptide antigen	P	The process in which an antigen-presenting cell expresses peptide antigen in association with an MHC protein complex on its cell surface, including proteolysis and transport steps for the peptide antigen both prior to and following assembly with the MHC protein complex. The peptide antigen is typically, but not always, processed from an endogenous or exogenous protein.
48003	antigen processing and presentation of lipid antigen via MHC class Ib	P	The process in which an antigen-presenting cell expresses lipid antigen in association with an MHC class Ib protein complex on its cell surface, including lipid extraction, degradation, and transport steps for the lipid antigen both prior to and following assembly with the MHC protein complex. The lipid antigen may originate from an endogenous or exogenous source of lipid. Class Ib here refers to non-classical class I molecules, such as those of the CD1 family.
48006	antigen processing and presentation, endogenous lipid antigen via MHC class Ib	P	The process in which an antigen-presenting cell expresses lipid antigen of endogenous origin in association with an MHC class Ib protein complex on its cell surface. Class Ib here refers to non-classical class I molecules, such as those of the CD1 family.
48007	antigen processing and presentation, exogenous lipid antigen via MHC class Ib	P	The process in which an antigen-presenting cell expresses lipid antigen of exogenous origin in association with an MHC class Ib protein complex on its cell surface. Class Ib here refers to non-classical class I molecules, such as those of the CD1 family.
48008	platelet-derived growth factor receptor signaling pathway	P	The series of molecular signals generated as a consequence of a platelet-derived growth factor receptor binding to one of its physiological ligands.
48009	insulin-like growth factor receptor signaling pathway	P	The series of molecular signals generated as a consequence of the insulin-like growth factor receptor binding to one of its physiological ligands.
48010	vascular endothelial growth factor receptor signaling pathway	P	Any series of molecular signals initiated by the binding of an extracellular ligand to a vascular endothelial growth factor receptor (VEGFR) located on the surface of the receiving cell, and ending with regulation of a downstream cellular process, e.g. transcription.
48011	neurotrophin TRK receptor signaling pathway	P	A series of molecular signals initiated by the binding of a neurotrophin to a receptor on the surface of the target cell where the receptor possesses tyrosine kinase activity, and ending with regulation of a downstream cellular process, e.g. transcription.
48012	hepatocyte growth factor receptor signaling pathway	P	The series of molecular signals generated as a consequence of the hepatocyte growth factor receptor binding to one of its physiological ligands.
48013	ephrin receptor signaling pathway	P	The series of molecular signals generated as a consequence of an ephrin receptor binding to an ephrin.
48014	Tie signaling pathway	P	The series of molecular signals generated as a consequence of a Tie protein (a receptor) binding to one of its physiological ligands (an angiopoietin).
48015	phosphatidylinositol-mediated signaling	P	A series of molecular signals in which a cell uses a phosphatidylinositol-mediated signaling to convert a signal into a response. Phosphatidylinositols include phosphatidylinositol (PtdIns) and its phosphorylated derivatives.
48016	inositol phosphate-mediated signaling	P	Any intracellular signal transduction in which the signal is passed on within the cell via an inositol phosphate. Includes production of the inositol phosphate, and downstream effectors that further transmit the signal within the cell. Inositol phosphates are a group of mono- to poly-phosphorylated inositols, and include inositol monophosphate (IP), inositol trisphosphate (IP3), inositol pentakisphosphate (IP5) and inositol hexaphosphate (IP6).
48017	inositol lipid-mediated signaling	P	A series of molecular signals in which a cell uses an inositol-containing lipid to convert a signal into a response. Inositol lipids include the phosphoinositides (phosphatidylinositol and its phosphorylated derivatives), ceramides containing inositol, and inositol glycolipids.
48018	receptor agonist activity	F	Interacts with receptors such that the proportion of receptors in the active form is increased.
48019	receptor antagonist activity	F	Interacts with receptors to reduce the action of another ligand, the agonist.
48020	CCR chemokine receptor binding	F	Interacting selectively and non-covalently with a CCR chemokine receptor.
48021	regulation of melanin biosynthetic process	P	Any process that alters the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of melanin.
48022	negative regulation of melanin biosynthetic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of melanin.
48023	positive regulation of melanin biosynthetic process	P	Any process that activates or increases the rate or extent of the chemical reactions and pathways resulting in the formation of melanin.
48024	regulation of mRNA splicing, via spliceosome	P	Any process that modulates the frequency, rate or extent of mRNA splicing via a spliceosomal mechanism.
48025	negative regulation of mRNA splicing, via spliceosome	P	Any process that stops, prevents or reduces the rate or extent of mRNA splicing via a spliceosomal mechanism.
48026	positive regulation of mRNA splicing, via spliceosome	P	Any process that activates or increases the rate or extent of mRNA splicing via a spliceosomal mechanism.
48027	mRNA 5'-UTR binding	F	Interacting selectively and non-covalently with the 5' untranslated region of an mRNA molecule.
48028	galacturonan binding	F	Interacting selectively and non-covalently with any simple or complex galacturonan. Galacturonan is any glycan composed solely of galacturonic acid residues, a specific type of glycuronan, and a constituent of some pectins.
48029	monosaccharide binding	F	Interacting selectively and non-covalently with any monosaccharide. Monosaccharides are the simplest carbohydrates; they are polyhydroxy aldehydes H[CH(OH)]nC(=O)H or polyhydroxy ketones H[CHOH]nC(=O)[CHOH]mH with three or more carbon atoms. They form the constitutional repeating units of oligo- and polysaccharides.
48030	disaccharide binding	F	Interacting selectively and non-covalently with any disaccharide. Disaccharides are sugars composed of two monosaccharide units.
48031	trisaccharide binding	F	Interacting selectively and non-covalently with any trisaccharide. Trisaccharides are sugars composed of three monosaccharide units.
48032	galacturonate binding	F	Interacting selectively and non-covalently with any galacturonate. Galacturonate is the anion of galacturonic acid, the uronic acid formally derived from galactose by oxidation of the hydroxymethylene group at C-6 to a carboxyl group.
48033	heme o metabolic process	P	The chemical reactions and pathways involving heme O, a derivative of heme containing a 17-carbon hydroxyethylfarnesyl side chain at position 8 of the tetrapyrrole macrocycle.
48034	heme O biosynthetic process	P	The chemical reactions and pathways resulting in the formation of heme O, a derivative of heme containing a 17-carbon hydroxyethylfarnesyl side chain at position 8 of the tetrapyrrole macrocycle.
48035	heme o catabolic process	P	The chemical reactions and pathways resulting in the breakdown of heme O, a derivative of heme containing a 17-carbon hydroxyethylfarnesyl side chain at position 8 of the tetrapyrrole macrocycle.
48036	central complex development	P	The process whose specific outcome is the progression of the central complex over time, from its formation to the mature structure. The central complex region of the insect brain is thought to be crucial for control of locomotive behavior. Located in the middle of the two protocerebral hemispheres, it comprises four neuropilar regions, the fan-shaped body, the ellipsoid body, the protocerebral bridge and the paired noduli.
48037	cofactor binding	F	Interacting selectively and non-covalently with a cofactor, a substance that is required for the activity of an enzyme or other protein. Cofactors may be inorganic, such as the metal atoms zinc, iron, and copper in certain forms, or organic, in which case they are referred to as coenzymes. Cofactors may either be bound tightly to active sites or bind loosely with the substrate.
48038	quinone binding	F	Interacting selectively and non-covalently with a quinone, any member of a class of diketones derivable from aromatic compounds by conversion of two CH groups into CO groups with any necessary rearrangement of double bonds.
48039	ubiquinone binding	F	Interacting selectively and non-covalently with ubiquinone, a quinone derivative with a tail of isoprene units.
48040	UDP-glucuronate decarboxylase activity	F	Catalysis of the reaction: H(+) + UDP-alpha-D-glucuronate = CO(2) + UDP-alpha-D-xylose.
48041	focal adhesion assembly	P	The aggregation and bonding together of a set of components to form a focal adhesion, a complex of intracellular signaling and structural proteins that provides a structural link between the internal actin cytoskeleton and the ECM, and also function as a locus of signal transduction activity.
48042	regulation of post-mating oviposition	P	Any process that modulates the frequency, rate or extent of the deposition of eggs, either fertilized or not, upon a surface or into a medium, following mating.
48045	trans-pentaprenyltranstransferase activity	F	Catalysis of the reaction: all-trans-pentaprenyl diphosphate + isopentenyl diphosphate = all-trans-hexaprenyl diphosphate + diphosphate.
48046	apoplast	C	The cell membranes and intracellular regions in a plant are connected through plasmodesmata, and plants may be described as having two major compartments: the living symplast and the non-living apoplast. The apoplast is external to the plasma membrane and includes cell walls, intercellular spaces and the lumen of dead structures such as xylem vessels. Water and solutes pass freely through it.
48047	mating behavior, sex discrimination	P	The behavior of individuals for the purpose of discriminating between the sexes, for the purpose of finding a suitable mating partner.
48048	embryonic eye morphogenesis	P	The process occurring in the embryo by which the anatomical structures of the post-embryonic eye are generated and organized.
48050	post-embryonic eye morphogenesis	P	The process, occurring after embryonic development, by which the anatomical structures of the eye are generated and organized. The eye is the organ of sight.
48052	R1/R6 cell differentiation	P	The process in which relatively unspecialized cells acquire the specialized features of R1 and R6 photoreceptors. An example of this process is found in Drosophila melanogaster.
48053	R1/R6 development	P	The process whose specific outcome is the progression of the R1 and R6 pair of photoreceptors in the eye over time, from their formation to the mature structures. R1 and R6 are paired photoreceptors that contribute to the outer rhabdomeres. An example of this process is found in Drosophila melanogaster.
48054	R2/R5 cell differentiation	P	The process in which relatively unspecialized cells acquire the specialized features of R2 and R5 photoreceptors. An example of this process is found in Drosophila melanogaster.
48055	R2/R5 development	P	The process whose specific outcome is the progression of the R2 and R5 pair of photoreceptors in the eye over time, from their formation to the mature structures. R2 and R5 are paired photoreceptors that contribute to the outer rhabdomeres. An example of this process is found in Drosophila melanogaster.
48056	R3/R4 cell differentiation	P	The process in which relatively unspecialized cells acquire the specialized features of R3 and R4 photoreceptors. An example of this process is found in Drosophila melanogaster.
48057	R3/R4 development	P	The process whose specific outcome is the progression of the R3 and R4 pair of photoreceptors in the eye over time, from their formation to the mature structures. R3 and R4 are paired photoreceptors that contribute to the outer rhabdomeres. An example of this process is found in Drosophila melanogaster.
48058	compound eye corneal lens development	P	The process whose specific outcome is the progression of the corneal lens in the compound eye over time, from its formation to the mature structure. The corneal lens is a chitinous extracellular secretion of the four underlying cone cells and the pigment cells.
48060	negative gravitaxis	P	The directed movement of a motile cell or organism away from the source of gravity.
48061	positive gravitaxis	P	The directed movement of a motile cell or organism towards the source of gravity.
48065	male courtship behavior, veined wing extension	P	The process during courtship where the male insect extends his wings. An example of this process is found in Drosophila melanogaster.
48066	developmental pigmentation	P	The developmental process that results in the deposition of coloring matter in an organism, tissue or cell.
48067	cuticle pigmentation	P	Establishment of a pattern of pigment in the cuticle of an organism.
48069	eye pigmentation	P	Establishment of a pattern of pigment in the eye of an organism.
48070	regulation of developmental pigmentation	P	Any process that modulates the frequency, rate or extent of the developmental process that results in the deposition of coloring matter in an organism.
48071	sex-specific pigmentation	P	Establishment of a pattern of pigment in one sex that is not observed in the other sex.
48072	compound eye pigmentation	P	Establishment of a pattern of pigment in the compound eye.
48073	regulation of eye pigmentation	P	Any process that modulates the frequency, rate or extent of establishment of a pattern of pigment in the eye of an organism.
48074	negative regulation of eye pigmentation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of establishment of a pattern of pigment in the eye of an organism.
48075	positive regulation of eye pigmentation	P	Any process that activates or increases the frequency, rate or extent of establishment of a pattern of pigment in the eye of an organism.
48076	regulation of compound eye pigmentation	P	Any process that modulates the frequency, rate or extent of establishment of a pattern of pigment in the compound eye.
48077	negative regulation of compound eye pigmentation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of establishment of a pattern of pigment in the compound eye.
48078	positive regulation of compound eye pigmentation	P	Any process that activates or increases the frequency, rate or extent of establishment of a pattern of pigment in the compound eye.
48079	regulation of cuticle pigmentation	P	Any process that modulates the frequency, rate or extent of establishment of a pattern of pigment in the cuticle of an organism.
48080	negative regulation of cuticle pigmentation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of establishment of a pattern of pigment in the cuticle of an organism.
48081	positive regulation of cuticle pigmentation	P	Any process that activates or increases the frequency, rate or extent of establishment of a pattern of pigment in the cuticle of an organism.
48082	regulation of adult chitin-containing cuticle pigmentation	P	Any process that modulates the frequency, rate or extent of establishment of the adult pattern of pigmentation in the cuticle of an organism.
48083	negative regulation of adult chitin-containing cuticle pigmentation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of establishment of the adult pattern of pigmentation in the cuticle of an organism.
48084	positive regulation of adult chitin-containing cuticle pigmentation	P	Any process that activates or increases the frequency, rate or extent of establishment of the adult pattern of pigmentation in the cuticle of an organism.
48085	adult chitin-containing cuticle pigmentation	P	Establishment of the adult pattern of pigmentation in the chitin-containing cuticle of an organism. An example of this is the adult cuticle pigmentation process in Drosophila melanogaster.
48086	negative regulation of developmental pigmentation	P	Any process that decreases the frequency, rate or extent of the developmental process that results in the deposition of coloring matter in an organism.
48087	positive regulation of developmental pigmentation	P	Any process that increases the frequency, rate or extent of the developmental process that results in the deposition of coloring matter in an organism.
48088	regulation of male pigmentation	P	Any process that modulates the frequency, rate or extent of establishment of a pattern of pigment in males.
48089	regulation of female pigmentation	P	Any process that modulates the frequency, rate or extent of establishment of a pattern of pigment in females.
48090	negative regulation of female pigmentation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of establishment of a pattern of pigment in females.
48091	positive regulation of female pigmentation	P	Any process that activates or increases the frequency, rate or extent of establishment of a pattern of pigment in females.
48092	negative regulation of male pigmentation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of establishment of a pattern of pigment in males.
48093	positive regulation of male pigmentation	P	Any process that activates or increases the frequency, rate or extent of establishment of a pattern of pigment in males.
48094	male pigmentation	P	Establishment of a pattern of pigment in males.
48095	female pigmentation	P	Establishment of a pattern of pigment in females.
48096	chromatin-mediated maintenance of transcription	P	Maintenance of transcription by remodelling of chromatin into an 'open configuration'. Once established, this regulation is mitotically stable and is maintained over many cell divisions. It is also heritable.
48097	long-term maintenance of gene activation	P	Any mechanism, at the level of transcription or post-transcription, maintaining gene activation in the long-term.
48098	antennal joint development	P	The process whose specific outcome is the progression of the antennal joint over time, from its formation to the mature structure. The antennal joint is the joint between antennal segments.
48099	anterior/posterior lineage restriction, imaginal disc	P	Formation and/or maintenance of a lineage boundary between anterior and posterior compartments that cells cannot cross, thus separating the populations of cells in each compartment.
48100	wing disc anterior/posterior pattern formation	P	The establishment, maintenance and elaboration of the anterior/posterior axis of the wing disc, a precursor to the wing.
48101	calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity	F	Catalysis of the reaction: guanosine 3',5'-cyclic phosphate + H2O = guanosine 5'-phosphate. The reaction is calmodulin and calcium-sensitive.
48102	autophagic cell death	P	A form of programmed cell death that is accompanied by the formation of autophagosomes. Autophagic cell death is characterized by lack of chromatin condensation and massive vacuolization of the cytoplasm, with little or no uptake by phagocytic cells.
48103	somatic stem cell division	P	The self-renewing division of a somatic stem cell, a stem cell that can give rise to cell types of the body other than those of the germ-line.
48104	establishment of body hair or bristle planar orientation	P	Orientation of hairs or sensory bristles that cover the body surface of an adult, such that they all point in a uniform direction along the plane of the epithelium from which they project.
48105	establishment of body hair planar orientation	P	Orientation of body hairs, projections from the surface of an organism, such that the hairs all point in a uniform direction along the surface.
48106	establishment of thoracic bristle planar orientation	P	Orientation along the body surface of bristles, sensory organs originating from a sensory organ precursor cell, such that they all point in a uniform direction.
48107	4-amino-3-isothiazolidinone biosynthetic process	P	The chemical reactions and pathways resulting in the formation of 4-amino-3-isothiazolinone, five-membered saturated heterocyclic ring structures containing a sulfur and a nitrogen in the 1-position and 2-positions respectively.
48108	peptide cross-linking via 4-amino-3-isothiazolidinone	P	The formation of 4-amino-3-isothiazolinone cross-links by the formation of a sulfenylamide bond between cysteine or cysteine sulfenic acid, and the alpha-amido of the following residue.
48109	peptide cross-linking via 2-amino-3-isothiazolidinone-L-serine	P	The chemical reactions and pathways resulting in the formation of a peptidyl cysteine-peptidyl serine cross-link through a process of forming first an intermediate cysteine sulfenic acid by peroxide oxidation, followed by condensation with the alpha-amido of the following serine residue and the release of water.
48132	female germ-line stem cell asymmetric division	P	The self-renewing division of a germline stem cell in the female gonad, to produce a daughter stem cell and a daughter germ cell, which will divide to form the female gametes.
48133	male germ-line stem cell asymmetric division	P	The self-renewing division of a germline stem cell in the male gonad, to produce a daughter stem cell and a daughter germ cell, which will divide to form the male gametes.
48134	germ-line cyst formation	P	Formation of a group of interconnected cells derived from a single gonial founder cell.
48135	female germ-line cyst formation	P	Formation of a group of interconnected cells derived from a single female gonial founder cell.
48136	male germ-line cyst formation	P	Formation of a group of interconnected cells derived from a single male gonial founder cell.
48137	spermatocyte division	P	The meiotic divisions undergone by the primary and secondary spermatocytes to produce haploid spermatids.
48138	germ-line cyst encapsulation	P	Formation of a single follicular epithelium around the germ-line derived cells of a cyst.
48139	female germ-line cyst encapsulation	P	Formation of a single follicular epithelium around the germ-line derived cells of a cyst formed in the female gonad.
48140	male germ-line cyst encapsulation	P	Formation of a single follicular epithelium around the germ-line derived cells of a cyst formed in the male gonad.
48142	germarium-derived cystoblast division	P	The four rounds of incomplete mitosis undergone by a cystoblast to form a 16-cell cyst of interconnected cells within a germarium. Within the cyst, one cell differentiates into an oocyte while the rest become nurse cells. An example of this process is found in Drosophila melanogaster.
48143	astrocyte activation	P	A change in morphology and behavior of an astrocyte resulting from exposure to a cytokine, chemokine, cellular ligand, or soluble factor.
48144	fibroblast proliferation	P	The multiplication or reproduction of fibroblast cells, resulting in the expansion of the fibroblast population.
48145	regulation of fibroblast proliferation	P	Any process that modulates the frequency, rate or extent of multiplication or reproduction of fibroblast cells.
48146	positive regulation of fibroblast proliferation	P	Any process that activates or increases the frequency, rate or extent of multiplication or reproduction of fibroblast cells.
48147	negative regulation of fibroblast proliferation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of multiplication or reproduction of fibroblast cells.
48148	behavioral response to cocaine	P	Any process that results in a change in the behavior of an organism as a result of a cocaine stimulus.
48149	behavioral response to ethanol	P	Any process that results in a change in the behavior of an organism as a result of an ethanol stimulus.
48150	behavioral response to ether	P	Any process that results in a change in the behavior of an organism as a result of an ether stimulus.
48152	S100 beta biosynthetic process	P	The chemical reactions and pathways resulting in the formation of S100 beta protein. S100 is a small calcium and zinc binding protein produced in astrocytes that is implicated in Alzheimer's disease, Down Syndrome and ALS.
48153	S100 alpha biosynthetic process	P	The chemical reactions and pathways resulting in the formation of S100 alpha protein. S100 is a small calcium and zinc binding protein produced in astrocytes that is implicated in Alzheimer's disease, Down Syndrome and ALS.
48156	tau protein binding	F	Interacting selectively and non-covalently with tau protein. tau is a microtubule-associated protein, implicated in Alzheimer's disease, Down Syndrome and ALS.
48158	oogonium stage	P	The stage in mammalian oogenesis when the primordial germ cell is hardly distinguishable from other cortical cells of the ovary.
48159	primary oocyte stage	P	The stage in oogenesis when the oocyte has a nucleus slightly larger than those of the adjacent cells and is surrounded by a layer of loose squamous epithelial cells.
48160	primary follicle stage	P	The stage in oogenesis when a single layer of cuboidal follicle cells surrounds the oocyte. The oocyte nucleus is large.
48161	double layer follicle stage	P	The stage in oogenesis when a double layer of distinct follicle cells surrounds the oocyte. An example of this process is found in Mus musculus.
48162	multi-layer follicle stage	P	The stage in oogenesis when many layers of follicle cells surround the oocyte. There is a yolk nucleus (Balbiani's Body) near the germinal vesicle.
48163	scattered antral spaces stage	P	The stage in oogenesis when antral spaces begin to form in the follicle cells. Mitochondria form centers for yolk concentration.
48164	distinct antral spaces stage	P	The stage in oogenesis when the antral spaces become distinct and the first polar body forms.
48165	fused antrum stage	P	The stage in oogenesis when the antral spaces fuse to form a single antral space. The oocyte is suspended in the cumulus oophorous and the first polar body in the perivitelline space.
48166	mature follicle stage	P	The stage in oogenesis when the antrum is swollen with follicular fluid. The ovum is ready to erupt from the ovary and is arrested at metaphase of the second meiotic division.
48167	regulation of synaptic plasticity	P	A process that modulates synaptic plasticity, the ability of synapses to change as circumstances require. They may alter function, such as increasing or decreasing their sensitivity, or they may increase or decrease in actual numbers.
48168	regulation of neuronal synaptic plasticity	P	A process that modulates neuronal synaptic plasticity, the ability of neuronal synapses to change as circumstances require. They may alter function, such as increasing or decreasing their sensitivity, or they may increase or decrease in actual numbers.
48169	regulation of long-term neuronal synaptic plasticity	P	A process that modulates long-term neuronal synaptic plasticity, the ability of neuronal synapses to change long-term as circumstances require. Long-term neuronal synaptic plasticity generally involves increase or decrease in actual synapse numbers.
48170	positive regulation of long-term neuronal synaptic plasticity	P	A process that increases long-term neuronal synaptic plasticity, the ability of neuronal synapses to change long-term as circumstances require. Long-term neuronal synaptic plasticity generally involves increase or decrease in actual synapse numbers.
48171	negative regulation of long-term neuronal synaptic plasticity	P	A process that decreases long-term neuronal synaptic plasticity, the ability of neuronal synapses to change long-term as circumstances require. Long-term neuronal synaptic plasticity generally involves increase or decrease in actual synapse numbers.
48172	regulation of short-term neuronal synaptic plasticity	P	A process that modulates short-term neuronal synaptic plasticity, the ability of neuronal synapses to change in the short-term as circumstances require. Short-term neuronal synaptic plasticity generally involves increasing or decreasing synaptic sensitivity.
48173	positive regulation of short-term neuronal synaptic plasticity	P	A process that increases short-term neuronal synaptic plasticity, the ability of neuronal synapses to change in the short-term as circumstances require. Short-term neuronal synaptic plasticity generally involves increasing or decreasing synaptic sensitivity.
48174	negative regulation of short-term neuronal synaptic plasticity	P	A process that decreases short-term neuronal synaptic plasticity, the ability of neuronal synapses to change in the short-term as circumstances require. Short-term neuronal synaptic plasticity generally involves increasing or decreasing synaptic sensitivity.
48175	hepatocyte growth factor biosynthetic process	P	The chemical reactions and pathways resulting in the formation of hepacyte growth factor. Hepatocyte growth factor is a mitogen for a number of cell types and it is found in liver cells and in many other cell types, including platelets.
48176	regulation of hepatocyte growth factor biosynthetic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of hepatocyte growth factor.
48177	positive regulation of hepatocyte growth factor biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of hepatocyte growth factor.
48178	negative regulation of hepatocyte growth factor biosynthetic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of hepatocyte growth factor.
48179	activin receptor complex	C	A protein complex that acts as an activin receptor. Heterodimeric activin receptors, comprising one Type I activin receptor and one Type II receptor polypeptide, and heterotrimeric receptors have been observed.
48180	activin complex	C	A nonsteroidal regulator, composed of two covalently linked inhibin beta subunits, inhibin beta-A and inhibin beta-B (sometimes known as activin beta or activin/inhibin beta). There are three forms of activin complex, activin A, which is composed of 2 inhibin beta-A subunits, activin B, which is composed of 2 inhibin beta-B subunits, and activin AB, which is composed of an inhibin beta-A and an inhibin beta-B subunit.
48183	activin AB complex	C	A nonsteroidal regulator, composed of two covalently linked inhibin beta subunits (sometimes known as activin beta or activin/inhibin beta), inhibin beta-A and inhibin beta-B.
48185	activin binding	F	Interacting selectively and non-covalently with activin, a dimer of inhibin-beta subunits.
48188	Set1C/COMPASS complex	C	A conserved protein complex that catalyzes methylation of histone H3. In Saccharomyces the complex contains Shg1p, Sdc1p, Swd1p, Swd2p, Swd3p, Spp1p, Bre2p, and the trithorax-related Set1p; in mammals it contains the catalytic subunit (SETD1A or SETD1B), WDR5, WDR82, RBBP5, ASH2L/ASH2, CXXC1/CFP1, HCFC1 and DPY30.
48189	Lid2 complex	C	A protein complex that is thought to be involved in regulation of chromatin remodeling. In Schizosaccharomyces the complex contains Lid1p, Ash2p, Ecm5p, Snt2p, and Sdc1p.
48190	wing disc dorsal/ventral pattern formation	P	The establishment, maintenance and elaboration of the dorsal/ventral axis of the wing disc, a precursor to the adult wing.
48193	Golgi vesicle transport	P	The directed movement of substances into, out of or within the Golgi apparatus, mediated by vesicles.
48194	Golgi vesicle budding	P	The evagination of the Golgi membrane, resulting in formation of a vesicle.
48195	Golgi membrane priming complex assembly	P	The aggregation, arrangement and bonding together of a set of components to form a membrane priming complex. An incoming coat component recognizes both GTPase and a membrane protein to form the priming complex.
48197	Golgi membrane coat protein complex assembly	P	The aggregation, arrangement and bonding together of priming complexes to form a coat on a Golgi membrane. Priming complexes associate laterally and additional coat proteins are recruited from the cytosol to the forming coat. Cargo proteins diffuse into the budding site and become trapped by their interactions with the coat.
48198	Golgi vesicle bud deformation and release	P	The process in which cytosolic coat proteins fit together in a basketlike convex framework to form a coated deformed region on the cytoplasmic surface of the membrane. The deformed region forms into a complete vesicle and is released.
48199	vesicle targeting, to, from or within Golgi	P	The process in which vesicles are directed to specific destination membranes during transport to, from or within the Golgi apparatus; mediated by the addition of specific coat proteins, including COPI and COPII proteins and clathrin, to the membrane during vesicle formation.
48200	Golgi transport vesicle coating	P	The addition of specific coat proteins to Golgi membranes during the formation of transport vesicles.
48201	vesicle targeting, plasma membrane to endosome	P	The process in which vesicles formed at the plasma membrane are directed to specific destinations in endosome membranes, mediated by molecules at the vesicle membrane and target membrane surfaces.
48202	clathrin coating of Golgi vesicle	P	The addition of clathrin and adaptor proteins to Golgi membranes during the formation of transport vesicles, forming a vesicle coat.
48203	vesicle targeting, trans-Golgi to endosome	P	The process in which vesicles are directed to specific destination membranes during transport from the trans-Golgi to the endosome.
48204	vesicle targeting, inter-Golgi cisterna	P	The process in which vesicles are directed to specific destination membranes during transport from one Golgi cisterna to another.
48205	COPI coating of Golgi vesicle	P	The addition of COPI proteins and adaptor proteins to Golgi membranes during the formation of transport vesicles, forming a vesicle coat.
48206	vesicle targeting, cis-Golgi to rough ER	P	The process in which vesicles are directed to specific destination membranes during transport from the cis-Golgi to the rough ER.
48207	vesicle targeting, rough ER to cis-Golgi	P	The process in which vesicles are directed to specific destination membranes during transport from the rough endoplasmic reticulum to the cis-Golgi.
48208	COPII vesicle coating	P	The addition of COPII proteins and adaptor proteins to ER membranes during the formation of transport vesicles, forming a vesicle coat.
48209	regulation of vesicle targeting, to, from or within Golgi	P	Any process that modulates the frequency, rate, or destination of vesicle-mediated transport to, from or within the Golgi apparatus.
48210	Golgi vesicle fusion to target membrane	P	The joining of the lipid bilayer membrane around a Golgi transport vesicle to the target lipid bilayer membrane.
48211	Golgi vesicle docking	P	The initial attachment of a Golgi transport vesicle membrane to a target membrane, mediated by proteins protruding from the membrane of the Golgi vesicle and the target membrane.
48212	Golgi vesicle uncoating	P	The process in which Golgi vesicle coat proteins are depolymerized, and released for reuse.
48213	Golgi vesicle prefusion complex stabilization	P	The binding of specific proteins to the t-SNARE/v-SNARE/SNAP25 complex, by which the Golgi vesicle prefusion complex is stabilized.
48214	regulation of Golgi vesicle fusion to target membrane	P	Any process that modulates the frequency, rate or extent of Golgi vesicle fusion to target membrane.
48215	positive regulation of Golgi vesicle fusion to target membrane	P	Any process that activates or increases the frequency, rate or extent of Golgi vesicle fusion to target membrane.
48216	negative regulation of Golgi vesicle fusion to target membrane	P	Any process that stops, prevents, or reduces the frequency, rate or extent of Golgi vesicle fusion to target membrane.
48217	pectic matrix	C	The gel-like pectin matrix consists of the interlinked acidic and neutral pectin networks that are further cross-linked by calcium bridges. Pectins consist largely of long chains of mostly galacturonic acid units (typically 1,4 linkages and sometimes methyl esters). Three major pectic polysaccharides (homogalacturonan, rhamnogalacturonan I and rhamnogalacturonan II) are thought to occur in all primary cell walls.
48219	inter-Golgi cisterna vesicle-mediated transport	P	The directed movement of substances from one Golgi cisterna to another, mediated by small transport vesicles.
48222	glycoprotein network	C	An extracellular matrix part that consists of cross-linked glycoproteins.
48223	hemicellulose network	C	Network composed of hemicelluloses; members of a class of plant cell wall polysaccharide that cannot be extracted from the wall by hot water or chelating agents, but can be extracted by aqueous alkali. Includes xylan, glucuronoxylan, arabinoxylan, arabinogalactan II, glucomannan, xyloglucan and galactomannan.
48224	lignin network	C	An extracellular matrix part that consists of lignin in the form of a three-dimensional polymeric network. Lignins are complex racemic aromatic heteropolymers derived from a variety of phenylpropane monomers coupled together by an assortment of carbon-carbon and ether linkages. Lignin is crucial for structural integrity of the cell wall and stiffness and strength of the stem. In addition, lignin waterproofs the cell wall, enabling transport of water and solutes through the vascular system, and plays a role in protecting plants against pathogens.
48225	suberin network	C	An extracellular matrix part that consists of fatty acid-derived polymers, including both aromatic and aliphatic components. The suberin network is found in specialized plant cell walls, where it is laid down between the primary wall and plasma membrane, forms protective and wound-healing layers, and provides a water-impermeable diffusion barrier.
48226	Casparian strip	C	Region of plant cell wall specialised to act as a seal to prevent back leakage of secreted material (analogous to tight junction between epithelial cells). Found particularly where root parenchymal cells secrete solutes into xylem vessels. The barrier is composed of suberin; a fatty substance, containing long chain fatty acids and fatty esters, also found in the cell walls of cork cells (phellem) in higher plants.
48227	plasma membrane to endosome transport	P	Transport of a vesicle from the plasma membrane to the endosome.
48229	gametophyte development	P	The process whose specific outcome is the progression of the gametophyte over time, from its formation to the mature structure. The gametophyte is the gamete-producing individual or phase in the life cycle having alternation of generations. An example of this process is found in Arabidopsis thaliana.
48232	male gamete generation	P	Generation of the male gamete; specialised haploid cells produced by meiosis and along with a female gamete takes part in sexual reproduction.
48235	pollen sperm cell differentiation	P	The process in which a relatively unspecialized cell acquires specialized features of a haploid sperm cell within the plant gametophyte.
48236	plant-type sporogenesis	P	The formation of plant spores derived from the products of meiosis. The spore gives rise to gametophytes.
48237	rough endoplasmic reticulum lumen	C	The volume enclosed by the membranes of the rough endoplasmic reticulum.
48238	smooth endoplasmic reticulum lumen	C	The volume enclosed by the membranes of the smooth endoplasmic reticulum.
48239	negative regulation of DNA recombination at telomere	P	Any process that stops, prevents, or reduces the frequency, rate or extent of genetic recombination within the telomere.
48240	sperm capacitation	P	A process required for sperm to reach fertilization competence. Sperm undergo an incompletely understood series of morphological and molecular maturational processes, termed capacitation, involving, among other processes, protein tyrosine phosphorylation and increased intracellular calcium.
48241	epinephrine transport	P	The directed movement of epinephrine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
48242	epinephrine secretion	P	The regulated release of epinephrine by a cell. Epinephrine is a catecholamine hormone secreted by the adrenal medulla and a neurotransmitter, released by certain neurons and active in the central nervous system.
48243	norepinephrine secretion	P	The regulated release of norepinephrine by a cell. Norepinephrine is a catecholamine and it acts as a hormone and as a neurotransmitter of most of the sympathetic nervous system.
48244	phytanoyl-CoA dioxygenase activity	F	Catalysis of the reaction: 2-oxoglutarate + O(2) + phytanoyl-CoA = 2-hydroxyphytanoyl-CoA + CO(2) + succinate.
48245	eosinophil chemotaxis	P	The movement of an eosinophil in response to an external stimulus.
48246	macrophage chemotaxis	P	The movement of a macrophage in response to an external stimulus.
48247	lymphocyte chemotaxis	P	The directed movement of a lymphocyte in response to an external stimulus.
48248	CXCR3 chemokine receptor binding	F	Interacting selectively and non-covalently with a the CXCR3 chemokine receptor.
48249	high-affinity phosphate transmembrane transporter activity	F	Enables the transfer of phosphate from one side of the membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.
48250	mitochondrial iron ion transport	P	The directed movement of iron ions into, out of or within a mitochondrion.
48251	elastic fiber assembly	P	Assembly of the extracellular matrix fibers that enables the matrix to recoil after transient stretching.
48252	lauric acid metabolic process	P	The chemical reactions and pathways involving lauric acid, a fatty acid with the formula CH3(CH2)10COOH. Derived from vegetable sources.
48254	snoRNA localization	P	Any process in which small nucleolar RNA is transported to, or maintained in, a specific location.
48255	mRNA stabilization	P	Prevention of degradation of mRNA molecules. In the absence of compensating changes in other processes, the slowing of mRNA degradation can result in an overall increase in the population of active mRNA molecules.
48256	flap endonuclease activity	F	Catalysis of the cleavage of a flap structure in DNA, but not other DNA structures; processes the ends of Okazaki fragments in lagging strand DNA synthesis.
48257	3'-flap endonuclease activity	F	Catalysis of the cleavage of a 3' flap structure in DNA, but not other DNA structures; processes the 3' ends of Okazaki fragments in lagging strand DNA synthesis.
48258	3-ketoglucose-reductase activity	F	Catalysis of the reaction: NADP+ + 3-dehydro-alpha-D-glucose = NADPH + alpha-D-glucose.
48259	regulation of receptor-mediated endocytosis	P	Any process that modulates the frequency, rate or extent of receptor mediated endocytosis, the uptake of external materials by cells, utilizing receptors to ensure specificity of transport.
48260	positive regulation of receptor-mediated endocytosis	P	Any process that activates or increases the frequency, rate or extent of receptor mediated endocytosis, the uptake of external materials by cells, utilizing receptors to ensure specificity of transport.
48261	negative regulation of receptor-mediated endocytosis	P	Any process that stops, prevents, or reduces the frequency, rate or extent of receptor mediated endocytosis, the uptake of external materials by cells, utilizing receptors to ensure specificity of transport.
48262	determination of dorsal/ventral asymmetry	P	Determination of asymmetry from the dorsal to the ventral side; as, the dorsoventral axis.
48263	determination of dorsal identity	P	Determination of the identity of part of an organism or organ where those parts are of the type that occur in the dorsal region. Identity is considered to be the aggregate of characteristics by which a structure is recognized.
48264	determination of ventral identity	P	The regionalization process that results in the determination of the identity of part of an organism or organ where those parts are of the type that occur in the ventral region. Identity is considered to be the aggregate of characteristics by which a structure is recognized.
48265	response to pain	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pain stimulus. Pain stimuli cause activation of nociceptors, peripheral receptors for pain, include receptors which are sensitive to painful mechanical stimuli, extreme heat or cold, and chemical stimuli.
48266	behavioral response to pain	P	Any process that results in a change in the behavior of an organism as a result of a pain stimulus. Pain stimuli cause activation of nociceptors, peripheral receptors for pain, include receptors which are sensitive to painful mechanical stimuli, extreme heat or cold, and chemical stimuli.
48268	clathrin coat assembly	P	The process that results in the assembly of clathrin triskelia into the ordered structure known as a clathrin cage.
48269	methionine adenosyltransferase complex	C	A multimeric enzyme complex composed of variable numbers of catalytic alpha subunits, and noncatalytic beta subunits. The beta subunits are believed to have a regulatory function. The enzyme complex catalyzes the synthesis of S-adenosylmethionine (AdoMet), which is the major methyl group donor, participating in the methylation of proteins, DNA, RNA, phospholipids, and other small molecules.
48270	methionine adenosyltransferase regulator activity	F	Modulates the activity of methionine adenosyltransferase.
48273	mitogen-activated protein kinase p38 binding	F	Interacting selectively and non-covalently with mitogen-activated protein kinase p38, an enzyme that catalyzes the transfer of phosphate from ATP to hydroxyl side chains on proteins in response to mitogen activation.
48275	N-terminal peptidyl-arginine acetylation	P	The acetylation of the N-terminal arginine of proteins; catalyzed by an uncharacterized arginyl-peptide alpha-N-acetyltransferase.
48278	vesicle docking	P	The initial attachment of a transport vesicle membrane to the target membrane, mediated by proteins protruding from the membrane of the vesicle and the target membrane. Docking requires only that the two membranes come close enough for these proteins to interact and adhere.
48279	vesicle fusion with endoplasmic reticulum	P	The joining of the lipid bilayer membrane around a vesicle to the lipid bilayer membrane around the endoplasmic reticulum.
48280	vesicle fusion with Golgi apparatus	P	The joining of the lipid bilayer membrane around a vesicle to the lipid bilayer membrane around the Golgi.
48281	inflorescence morphogenesis	P	The process in which the anatomical structures of inflorescences are generated and organized. An inflorescence is the part of a seed plant body that is usually above ground and that can bear flowers.
48282	determinate inflorescence morphogenesis	P	The process in which the anatomical structures of determinate inflorescences are generated and organized. A determinate inflorescence is one that can only produce a predetermined number of floral meristems.
48283	indeterminate inflorescence morphogenesis	P	The process in which the anatomical structures of determinate inflorescences are generated and organized. A determinate inflorescence is one that can produce an undefined number of floral meristems.
48284	organelle fusion	P	The creation of a single organelle from two or more organelles.
48285	organelle fission	P	The creation of two or more organelles by division of one organelle.
48286	lung alveolus development	P	The process whose specific outcome is the progression of the alveolus over time, from its formation to the mature structure. The alveolus is a sac for holding air in the lungs; formed by the terminal dilation of air passageways.
48288	nuclear membrane fusion involved in karyogamy	P	The joining of 2 or more lipid bilayer membranes that surround the nucleus during the creation of a single nucleus from multiple nuclei.
48289	isotype switching to IgE isotypes	P	The switching of activated B cells from IgM biosynthesis to IgE biosynthesis, accomplished through a recombination process involving an intrachromosomal deletion between switch regions that reside 5' of the IgM and IgE constant region gene segments in the immunoglobulin heavy chain locus.
48290	isotype switching to IgA isotypes	P	The switching of activated B cells from IgM biosynthesis to biosynthesis of an IgA isotype, accomplished through a recombination process involving an intrachromosomal deletion between switch regions that reside 5' of the IgM and one of the IgA constant region gene segments in the immunoglobulin heavy chain locus.
48291	isotype switching to IgG isotypes	P	The switching of activated B cells from IgM biosynthesis to biosynthesis of an IgG isotype, accomplished through a recombination process involving an intrachromosomal deletion between switch regions that reside 5' of the IgM and one of the IgG constant region gene segments in the immunoglobulin heavy chain locus.
48292	isotype switching to IgD isotypes	P	The switching of activated B cells from IgM biosynthesis to IgD biosynthesis, accomplished through a recombination process involving an intrachromosomal deletion between switch regions that reside 5' of the IgM and IgD constant region gene segments in the immunoglobulin heavy chain locus.
48293	regulation of isotype switching to IgE isotypes	P	Any process that modulates the frequency, rate or extent of isotype switching to IgE isotypes.
48294	negative regulation of isotype switching to IgE isotypes	P	Any process that stops, prevents, or reduces the frequency, rate or extent of isotype switching to IgE isotypes.
48295	positive regulation of isotype switching to IgE isotypes	P	Any process that activates or increases the frequency, rate or extent of isotype switching to IgE isotypes.
48296	regulation of isotype switching to IgA isotypes	P	Any process that modulates the frequency, rate or extent of isotype switching to IgA isotypes.
48297	negative regulation of isotype switching to IgA isotypes	P	Any process that stops, prevents, or reduces the frequency, rate or extent of isotype switching to IgA isotypes.
48298	positive regulation of isotype switching to IgA isotypes	P	Any process that activates or increases the frequency, rate or extent of isotype switching to IgA isotypes.
48299	regulation of isotype switching to IgD isotypes	P	Any process that modulates the frequency, rate or extent of isotype switching to IgD isotypes.
48300	negative regulation of isotype switching to IgD isotypes	P	Any process that stops, prevents, or reduces the frequency, rate or extent of isotype switching to IgD isotypes.
48301	positive regulation of isotype switching to IgD isotypes	P	Any process that activates or increases the frequency, rate or extent of isotype switching to IgD isotypes.
48302	regulation of isotype switching to IgG isotypes	P	Any process that modulates the frequency, rate or extent of isotype switching to IgG isotypes.
48303	negative regulation of isotype switching to IgG isotypes	P	Any process that stops, prevents, or reduces the frequency, rate or extent of isotype switching to IgG isotypes.
48304	positive regulation of isotype switching to IgG isotypes	P	Any process that activates or increases the frequency, rate or extent of isotype switching to IgG isotypes.
48305	immunoglobulin secretion	P	The regulated release of immunoglobulins from a B cell or plasma cell, whose mechanism includes the use of alternate polyadenylylation signals to favor the biosynthesis of secreted forms of immunoglobulin over membrane-bound immunoglobulin.
48306	calcium-dependent protein binding	F	Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules), in the presence of calcium.
48307	ferredoxin-nitrite reductase activity	F	Catalysis of the reaction: NH3 + 2 H2O + 6 oxidized ferredoxin = nitrite + 6 reduced ferredoxin + 7 H+.
48308	organelle inheritance	P	The partitioning of organelles between daughter cells at cell division.
48309	endoplasmic reticulum inheritance	P	The partitioning of endoplasmic reticulum between daughter cells at cell division.
48310	nucleus inheritance	P	The partitioning of nuclei between daughter cells at cell division.
48311	mitochondrion distribution	P	Any process that establishes the spatial arrangement of mitochondria between and within cells.
48312	intracellular distribution of mitochondria	P	Any process that establishes the spatial arrangement of mitochondria within the cell.
48313	Golgi inheritance	P	The partitioning of Golgi apparatus between daughter cells at cell division.
48314	embryo sac morphogenesis	P	The process in which the anatomical structures of the embryo sac are generated and organized. The embryo sac develops from the megaspore in heterosporous plants.
48315	conidium formation	P	The process of producing non-motile spores, called conidia, via mitotic asexual reproduction in higher fungi. Conidia are haploid cells genetically identical to their haploid parent. They are produced by conversion of hyphal elements, or are borne on sporogenous cells on or within specialized structures termed conidiophores, and participate in dispersal of the fungus.
48316	seed development	P	The process whose specific outcome is the progression of the seed over time, from its formation to the mature structure. A seed is a propagating organ formed in the sexual reproductive cycle of gymnosperms and angiosperms, consisting of a protective coat enclosing an embryo and food reserves.
48317	seed morphogenesis	P	The process in which the anatomical structures of the seed are generated and organized.
48318	axial mesoderm development	P	The process whose specific outcome is the progression of the axial mesoderm over time, from its formation to the mature structure. The axial mesoderm includes the prechordal mesoderm and the chordamesoderm. It gives rise to the prechordal plate and to the notochord.
48319	axial mesoderm morphogenesis	P	The process in which the anatomical structures of the axial mesoderm are generated and organized.
48320	axial mesoderm formation	P	The process that gives rise to the axial mesoderm. This process pertains to the initial formation of the structure from unspecified parts.
48321	axial mesodermal cell differentiation	P	The process in which a relatively unspecialized cell acquires specialized features of an axial mesoderm cell.
48322	axial mesodermal cell fate commitment	P	The process in which a cell becomes committed to become an axial mesoderm cell.
48323	axial mesodermal cell fate determination	P	The process in which a cell becomes capable of differentiating autonomously into an axial mesoderm cell regardless of its environment; upon determination, the cell fate cannot be reversed.
48324	regulation of axial mesodermal cell fate determination	P	Any process that modulates the frequency, rate or extent of axial mesoderm cell fate determination.
48325	negative regulation of axial mesodermal cell fate determination	P	Any process that stops, prevents, or reduces the frequency, rate or extent of axial mesoderm cell fate determination.
48326	positive regulation of axial mesodermal cell fate determination	P	Any process that activates or increases the frequency, rate or extent of axial mesoderm cell fate determination.
48327	axial mesodermal cell fate specification	P	The process in which a cell becomes capable of differentiating autonomously into an axial mesoderm cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.
48328	regulation of axial mesodermal cell fate specification	P	Any process that modulates the frequency, rate or extent of axial mesoderm cell fate specification.
48329	negative regulation of axial mesodermal cell fate specification	P	Any process that stops, prevents, or reduces the frequency, rate or extent of axial mesoderm cell fate specification.
48330	positive regulation of axial mesodermal cell fate specification	P	Any process that activates or increases the frequency, rate or extent of axial mesoderm cell fate specification.
48331	axial mesoderm structural organization	P	The process that contributes to the act of creating the structural organization of the axial mesoderm. This process pertains to the physical shaping of a rudimentary structure.
48332	mesoderm morphogenesis	P	The process in which the anatomical structures of the mesoderm are generated and organized.
48333	mesodermal cell differentiation	P	The process in which a relatively unspecialized cell acquires the specialized features of a mesoderm cell.
48334	regulation of mesodermal cell fate determination	P	Any process that modulates the frequency, rate or extent of mesoderm cell fate determination.
48335	negative regulation of mesodermal cell fate determination	P	Any process that stops, prevents, or reduces the frequency, rate or extent of mesoderm cell fate determination.
48336	positive regulation of mesodermal cell fate determination	P	Any process that activates or increases the frequency, rate or extent of mesoderm cell fate determination.
48337	positive regulation of mesodermal cell fate specification	P	Any process that activates or increases the frequency, rate or extent of mesoderm cell fate specification.
48338	mesoderm structural organization	P	The process that contributes to the act of creating the structural organization of the mesoderm. This process pertains to the physical shaping of a rudimentary structure.
48339	paraxial mesoderm development	P	The process whose specific outcome is the progression of the paraxial mesoderm over time, from its formation to the mature structure. The paraxial mesoderm is the mesoderm located bilaterally adjacent to the notochord and neural tube.
48340	paraxial mesoderm morphogenesis	P	The process in which the anatomical structures of the paraxial mesoderm are generated and organized.
48341	paraxial mesoderm formation	P	The process that gives rise to the paraxial mesoderm. This process pertains to the initial formation of the structure from unspecified parts.
48342	paraxial mesodermal cell differentiation	P	The process in which a relatively unspecialized cell acquires the specialized features of a paraxial mesoderm cell.
48343	paraxial mesodermal cell fate commitment	P	The process in which a cell becomes committed to become a paraxial mesoderm cell.
48344	paraxial mesodermal cell fate determination	P	The process in which a cell becomes capable of differentiating autonomously into a paraxial mesoderm cell regardless of its environment; upon determination, the cell fate cannot be reversed.
48345	regulation of paraxial mesodermal cell fate determination	P	Any process that modulates the frequency, rate or extent of paraxial mesoderm cell fate determination.
48346	positive regulation of paraxial mesodermal cell fate determination	P	Any process that activates or increases the frequency, rate or extent of paraxial mesoderm cell fate determination.
48347	negative regulation of paraxial mesodermal cell fate determination	P	Any process that stops, prevents, or reduces the frequency, rate or extent of paraxial mesoderm cell fate determination.
48348	paraxial mesodermal cell fate specification	P	The process in which a cell becomes capable of differentiating autonomously into a paraxial mesoderm cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.
48349	regulation of paraxial mesodermal cell fate specification	P	Any process that modulates the frequency, rate or extent of paraxial mesoderm cell fate specification.
48350	positive regulation of paraxial mesodermal cell fate specification	P	Any process that activates or increases the frequency, rate or extent of paraxial mesoderm cell fate specification.
48351	negative regulation of paraxial mesodermal cell fate specification	P	Any process that stops, prevents, or reduces the frequency, rate or extent of paraxial mesoderm cell fate specification.
48352	paraxial mesoderm structural organization	P	The process that contributes to the act of creating the structural organization of the paraxial mesoderm. This process pertains to the physical shaping of a rudimentary structure.
48353	primary endosperm nucleus	C	Nucleus resulting from the fusion of the male gamete and two polar nuclei in the central cell of the embryo sac.
48354	mucilage biosynthetic process involved in seed coat development	P	The chemical reactions and pathways resulting in the formation of mucilage that occur as part of seed coat development; mucilage is normally synthesized during seed coat development.
48355	root cap mucilage biosynthetic process	P	The chemical reactions and pathways resulting in the formation of mucilage that occur in the root cap; mucilage is normally synthesized during root growth.
48356	root epithelial mucilage biosynthetic process	P	The chemical reactions and pathways resulting in the formation of mucilage that occur in the root epithelium; mucilage is normally synthesized during root growth.
48357	pedicel mucilage biosynthetic process	P	The chemical reactions and pathways resulting in the formation of mucilage that occur in the flower stem.
48358	mucilage pectin biosynthetic process	P	The chemical reactions and pathways resulting in the formation of the pectin component of mucilage.
48359	mucilage metabolic process involved in seed coat development	P	The chemical reactions and pathways involving mucilage that occur as part of seed coat development; mucilage is normally synthesized during seed coat development.
48360	root cap mucilage metabolic process	P	The chemical reactions and pathways involving mucilage that occur in the root cap; mucilage is normally synthesized during root growth.
48361	root epithelial mucilage metabolic process	P	The chemical reactions and pathways involving mucilage that occur in the root epithelium; mucilage is normally synthesized during root growth.
48362	pedicel mucilage metabolic process	P	The chemical reactions and pathways involving mucilage that occur in the flower stem.
48363	mucilage pectin metabolic process	P	The chemical reactions and pathways involving the pectin component of mucilage.
48364	root development	P	The process whose specific outcome is the progression of the root over time, from its formation to the mature structure. The root is the water- and mineral-absorbing part of a plant which is usually underground, does not bear leaves, tends to grow downwards and is typically derived from the radicle of the embryo.
48365	Rac GTPase binding	F	Interacting selectively and non-covalently with Rac protein, any member of the Rac subfamily of the Ras superfamily of monomeric GTPases.
48366	leaf development	P	The process whose specific outcome is the progression of the leaf over time, from its formation to the mature structure.
48367	shoot system development	P	The process whose specific outcome is the progression of the shoot system over time, from its formation to the mature structure.
48368	lateral mesoderm development	P	The process whose specific outcome is the progression of the lateral mesoderm over time, from its formation to the mature structure.
48369	lateral mesoderm morphogenesis	P	The process in which the anatomical structures of the lateral mesoderm are generated and organized.
48370	lateral mesoderm formation	P	The process that gives rise to the lateral mesoderm. This process pertains to the initial formation of the structure from unspecified parts.
48371	lateral mesodermal cell differentiation	P	The process in which a relatively unspecialized cell acquires the specialized features of a lateral mesoderm cell.
48372	lateral mesodermal cell fate commitment	P	The process in which a cell becomes committed to become a lateral mesoderm cell.
48373	lateral mesodermal cell fate determination	P	The process in which a cell becomes capable of differentiating autonomously into a lateral mesoderm cell regardless of its environment; upon determination, the cell fate cannot be reversed.
48374	regulation of lateral mesodermal cell fate determination	P	Any process that modulates the frequency, rate or extent of lateral mesoderm cell fate determination.
48375	negative regulation of lateral mesodermal cell fate determination	P	Any process that stops, prevents, or reduces the frequency, rate or extent of lateral mesoderm cell fate determination.
48376	positive regulation of lateral mesodermal cell fate determination	P	Any process that activates or increases the frequency, rate or extent of lateral mesoderm cell fate determination.
48377	lateral mesodermal cell fate specification	P	The process in which a cell becomes capable of differentiating autonomously into a lateral mesoderm cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.
48378	regulation of lateral mesodermal cell fate specification	P	Any process that modulates the frequency, rate or extent of lateral mesoderm cell fate specification.
48379	positive regulation of lateral mesodermal cell fate specification	P	Any process that activates or increases the frequency, rate or extent of lateral mesoderm cell fate specification.
48380	negative regulation of lateral mesodermal cell fate specification	P	Any process that stops, prevents, or reduces the frequency, rate or extent of lateral mesoderm cell fate specification.
48381	lateral mesoderm structural organization	P	The process that contributes to the act of creating the structural organization of the lateral mesoderm. This process pertains to the physical shaping of a rudimentary structure.
48382	mesendoderm development	P	The process whose specific outcome is the progression of the mesendoderm over time, from its formation to the mature structure. In animal embryos, mesendoderm development gives rise to both mesoderm and endoderm tissues.
48383	mesectoderm development	P	The process whose specific outcome is the progression of the mesectoderm over time, from its formation to the mature structure. In animal embryos, mesectoderm development processes give rise to both mesoderm and ectoderm tissues.
48384	retinoic acid receptor signaling pathway	P	The series of molecular signals generated as a consequence of a retinoic acid receptor binding to one of its physiological ligands.
48385	regulation of retinoic acid receptor signaling pathway	P	Any process that modulates the frequency, rate or extent of retinoic acid receptor signaling pathway activity.
48386	positive regulation of retinoic acid receptor signaling pathway	P	Any process that activates or increases the frequency, rate or extent of retinoic acid receptor signaling pathway activity.
48387	negative regulation of retinoic acid receptor signaling pathway	P	Any process that stops, prevents, or reduces the frequency, rate or extent of retinoic acid receptor signaling pathway activity.
48388	endosomal lumen acidification	P	Any process that reduces the pH of the endosomal lumen, measured by the concentration of the hydrogen ion.
48389	intermediate mesoderm development	P	The process whose specific outcome is the progression of the intermediate mesoderm over time, from its formation to the mature structure. The intermediate mesoderm is located between the lateral mesoderm and the paraxial mesoderm. It develops into the kidney and gonads.
48390	intermediate mesoderm morphogenesis	P	The process in which the anatomical structures of the intermediate mesoderm are generated and organized.
48391	intermediate mesoderm formation	P	The process that gives rise to the intermediate mesoderm. This process pertains to the initial formation of the structure from unspecified parts.
48392	intermediate mesodermal cell differentiation	P	The process in which a relatively unspecialized cell acquires specialized features of an intermediate mesoderm cell.
48393	intermediate mesodermal cell fate commitment	P	The process in which the developmental fate of a cell becomes restricted such that it will develop into an intermediate mesoderm cell.
48394	intermediate mesodermal cell fate determination	P	The process in which a cell becomes capable of differentiating autonomously into a intermediate mesoderm cell regardless of its environment; upon determination, the cell fate cannot be reversed.
48395	regulation of intermediate mesodermal cell fate determination	P	Any process that modulates the frequency, rate or extent of intermediate mesoderm cell fate determination.
48396	negative regulation of intermediate mesodermal cell fate determination	P	Any process that stops, prevents, or reduces the frequency, rate or extent of intermediate mesoderm cell fate determination.
48397	positive regulation of intermediate mesodermal cell fate determination	P	Any process that activates or increases the frequency, rate or extent of intermediate mesoderm cell fate determination.
48398	intermediate mesodermal cell fate specification	P	The process in which a cell becomes capable of differentiating autonomously into an intermediate mesoderm cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.
48399	regulation of intermediate mesodermal cell fate specification	P	Any process that modulates the frequency, rate or extent of intermediate mesoderm cell fate specification.
48400	positive regulation of intermediate mesodermal cell fate specification	P	Any process that activates or increases the frequency, rate or extent of intermediate mesoderm cell fate specification.
48401	negative regulation of intermediate mesodermal cell fate specification	P	Any process that stops, prevents, or reduces the frequency, rate or extent of intermediate mesoderm cell fate specification.
48402	intermediate mesoderm structural organization	P	The process that contributes to the act of creating the structural organization of the intermediate mesoderm. This process pertains to the physical shaping of a rudimentary structure.
48403	brain-derived neurotrophic factor binding	F	Interacting selectively and non-covalently with brain-derived neurotrophic factor.
48406	nerve growth factor binding	F	Interacting selectively and non-covalently with nerve growth factor (NGF).
48407	platelet-derived growth factor binding	F	Interacting selectively and non-covalently with platelet-derived growth factor.
48408	epidermal growth factor binding	F	Interacting selectively and non-covalently with epidermal growth factor.
48437	floral organ development	P	The process whose specific outcome is the progression of the floral organ over time, from its formation to the mature structure.
48438	floral whorl development	P	The process whose specific outcome is the progression of a floral whorl over time, from its formation to the mature structure. A floral whorl is a circular arrangement of parts of a flower arising from a stem of a plant.
48439	flower morphogenesis	P	The process in which the anatomical structures of the flower are generated and organized.
48440	carpel development	P	The process whose specific outcome is the progression of the carpel over time, from its formation to the mature structure. A carpel is an organ (generally believed to be a modified foliar unit) at the centre of a flower, bearing one or more ovules and having its margins fused together or with other carpels to enclose the ovule in an ovary, and consisting also of a stigma and usually a style.
48441	petal development	P	The process whose specific outcome is the progression of the petal over time, from its formation to the mature structure.
48442	sepal development	P	The process whose specific outcome is the progression of the sepal over time, from its formation to the mature structure.
48443	stamen development	P	The process whose specific outcome is the progression of the stamen over time, from its formation to the mature structure.
48444	floral organ morphogenesis	P	The process in which the anatomical structures of the floral organ are generated and organized.
48445	carpel morphogenesis	P	The process in which the anatomical structures of the carpel are generated and organized.
48446	petal morphogenesis	P	The process in which the anatomical structures of the petal are generated and organized.
48447	sepal morphogenesis	P	The process in which the anatomical structures of the sepal are generated and organized.
48448	stamen morphogenesis	P	The process in which the anatomical structures of the stamen are generated and organized.
48449	floral organ formation	P	The process that gives rise to floral organs. This process pertains to the initial formation of a structure from unspecified parts.
48450	floral organ structural organization	P	The process that contributes to the act of creating the structural organization of floral organs. This process pertains to the physical shaping of a rudimentary structure.
48451	petal formation	P	The process that gives rise to the petal. This process pertains to the initial formation of a structure from unspecified parts.
48452	petal structural organization	P	The process that contributes to the act of creating the structural organization of the petal. This process pertains to the physical shaping of a rudimentary structure.
48453	sepal formation	P	The process that gives rise to the sepal. This process pertains to the initial formation of a structure from unspecified parts.
48454	sepal structural organization	P	The process that contributes to the act of creating the structural organization of the sepal. This process pertains to the physical shaping of a rudimentary structure.
48455	stamen formation	P	The process that contributes to the act of giving rise to the stamen. This process pertains to the initial formation of a structure from unspecified parts.
48456	stamen structural organization	P	The process that contributes to the act of creating the structural organization of the stamen. This process pertains to the physical shaping of a rudimentary structure.
48457	floral whorl morphogenesis	P	The process in which the anatomical structures of the floral whorl are generated and organized.
48458	floral whorl formation	P	The process that gives rise to the floral whorl. This process pertains to the initial formation of a structure from unspecified parts.
48459	floral whorl structural organization	P	The process that contributes to the act of creating the structural organization of the floral whorl. This process pertains to the physical shaping of a rudimentary structure.
48460	flower formation	P	The process that gives rise to the flower. This process pertains to the initial formation of a structure from unspecified parts.
48461	flower structural organization	P	The process that contributes to the act of creating the structural organization of the flower. This process pertains to the physical shaping of a rudimentary structure.
48462	carpel formation	P	The process that gives rise to the carpel. This process pertains to the initial formation of a structure from unspecified parts.
48463	carpel structural organization	P	The process that contributes to the act of creating the structural organization of the carpel. This process pertains to the physical shaping of a rudimentary structure.
48464	flower calyx development	P	The process whose specific outcome is the progression of the flower calyx over time, from its formation to the mature structure.
48465	corolla development	P	The process whose specific outcome is the progression of the corolla over time, from its formation to the mature structure.
48466	androecium development	P	The process whose specific outcome is the progression of the androecium over time, from its formation to the mature structure.
48467	gynoecium development	P	The process whose specific outcome is the progression of the gynoecium over time, from its formation to the mature structure. The gynoecium is the collective name for the carpels of a flower.
48468	cell development	P	The process whose specific outcome is the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate.
48469	cell maturation	P	A developmental process, independent of morphogenetic (shape) change, that is required for a cell to attain its fully functional state.
48471	perinuclear region of cytoplasm	C	Cytoplasm situated near, or occurring around, the nucleus.
48472	threonine-phosphate decarboxylase activity	F	Catalysis of the reaction: O-phospho-L-threonine + H(+) = (R)-1-aminopropan-2-yl phosphate + CO(2).
48473	D-methionine transport	P	The directed movement of D-methionine into, out of, within, or between cells.
48474	D-methionine transmembrane transporter activity	F	Enables the transfer of D-methionine from one side of a membrane to the other.
48475	coated membrane	C	A single or double lipid bilayer with any of several different proteinaceous coats that can associate with membranes. Membrane coats include those formed by clathrin plus an adaptor complex, the COPI and COPII complexes.
48476	Holliday junction resolvase complex	C	A protein complex that mediates the conversion of a Holliday junction into two separate duplex DNA molecules; the complex includes a single- or multisubunit helicase that catalyzes the extension of heteroduplex DNA by branch migration and a nuclease that resolves the junction by nucleolytic cleavage.
48477	oogenesis	P	The complete process of formation and maturation of an ovum or female gamete from a primordial female germ cell. Examples of this process are found in Mus musculus and Drosophila melanogaster.
48478	replication fork protection	P	Any process that prevents the collapse of stalled replication forks.
48479	style development	P	The process whose specific outcome is the progression of the style over time, from its formation to the mature structure. The style is an elongated part of a carpel, or group of fused carpels, and it lies between the ovary and the stigma.
48480	stigma development	P	The process whose specific outcome is the progression of the stigma over time, from its formation to the mature structure. The stigma is the pollen-receptive surface of a carpel or group of fused carpels, usually sticky.
48481	plant ovule development	P	The process whose specific outcome is the progression of the ovule over time, from its formation to the mature structure. The ovule is the structure in seed plants enclosing the female gametophyte, and is composed of the nucellus, one or two integuments, and the funiculus; it develops into the seed.
48482	plant ovule morphogenesis	P	The process in which the anatomical structures of the ovule are generated and organized. The ovule is the structure in seed plants enclosing the female gametophyte, and is composed of the nucellus, one or two integuments, and the funiculus; it develops into the seed.
48483	autonomic nervous system development	P	The process whose specific outcome is the progression of the autonomic nervous system over time, from its formation to the mature structure. The autonomic nervous system is composed of neurons that are not under conscious control, and is comprised of two antagonistic components, the sympathetic and parasympathetic nervous systems. The autonomic nervous system regulates key functions including the activity of the cardiac (heart) muscle, smooth muscles (e.g. of the gut), and glands.
48484	enteric nervous system development	P	The process whose specific outcome is the progression of the enteric nervous system over time, from its formation to the mature structure. The enteric nervous system is composed of two ganglionated neural plexuses in the gut wall which form one of the three major divisions of the autonomic nervous system. The enteric nervous system innervates the gastrointestinal tract, the pancreas, and the gall bladder. It contains sensory neurons, interneurons, and motor neurons. Thus the circuitry can autonomously sense the tension and the chemical environment in the gut and regulate blood vessel tone, motility, secretions, and fluid transport. The system is itself governed by the central nervous system and receives both parasympathetic and sympathetic innervation.
48485	sympathetic nervous system development	P	The process whose specific outcome is the progression of the sympathetic nervous system over time, from its formation to the mature structure. The sympathetic nervous system is one of the two divisions of the vertebrate autonomic nervous system (the other being the parasympathetic nervous system). The sympathetic preganglionic neurons have their cell bodies in the thoracic and lumbar regions of the spinal cord and connect to the paravertebral chain of sympathetic ganglia. Innervate heart and blood vessels, sweat glands, viscera and the adrenal medulla. Most sympathetic neurons, but not all, use noradrenaline as a post-ganglionic neurotransmitter.
48486	parasympathetic nervous system development	P	The process whose specific outcome is the progression of the parasympathetic nervous system over time, from its formation to the mature structure. The parasympathetic nervous system is one of the two divisions of the vertebrate autonomic nervous system. Parasympathetic nerves emerge cranially as pre ganglionic fibers from oculomotor, facial, glossopharyngeal and vagus and from the sacral region of the spinal cord. Most neurons are cholinergic and responses are mediated by muscarinic receptors. The parasympathetic system innervates, for example: salivary glands, thoracic and abdominal viscera, bladder and genitalia.
48487	beta-tubulin binding	F	Interacting selectively and non-covalently with the microtubule constituent protein beta-tubulin.
48488	synaptic vesicle endocytosis	P	Clathrin-mediated endocytosis of presynaptic membrane that recycles synaptic vesicle membrane and its components following synaptic vesicle exocytosis. This process starts with coating of the membrane with adaptor proteins and clathrin prior to invagination and ends when uncoating has finished.
48489	synaptic vesicle transport	P	The directed movement of synaptic vesicles.
48490	anterograde synaptic vesicle transport	P	The directed movement of synaptic vesicle along axonal microtubules from the cell body to the presynapse.
48491	retrograde synaptic vesicle transport	P	The directed movement of synaptic vesicle along axonal microtubules from the presynapse to the cell body.
48492	ribulose bisphosphate carboxylase complex	C	A complex containing either both large and small subunits or just small subunits which carries out the activity of producing 3-phosphoglycerate from carbon dioxide and ribulose-1,5-bisphosphate.
48493	plasma membrane-derived thylakoid ribulose bisphosphate carboxylase complex	C	A complex, located in the plasma membrane-derived thylakoid, containing either both large and small subunits or just small subunits. It carries out the activity of producing 3-phosphoglycerate from carbon dioxide and ribulose-1,5-bisphosphate.
48494	chromatophore ribulose bisphosphate carboxylase complex	C	A complex, located in the chromatophore, containing either both large and small subunits or just small subunits which carries out the activity of producing 3-phosphoglycerate from carbon dioxide and ribulose-1,5-bisphosphate.
48495	Roundabout binding	F	Interacting selectively and non-covalently with the Roundabout (ROBO) receptor, a transmembrane receptor.
48496	maintenance of animal organ identity	P	The process in which the identity of an animal organ is maintained. Identity is considered to be the aggregate of characteristics by which a structure is recognized.
48497	maintenance of floral organ identity	P	The process in which the identity of a floral organ is maintained. Identity is considered to be the aggregate of characteristics by which a structure is recognized.
48498	establishment of petal orientation	P	The process that determines the orientation of petals with reference to the central axis.
48499	synaptic vesicle membrane organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the membrane surrounding a synaptic vesicle.
48500	signal recognition particle	C	A complex of protein and RNA which facilitates translocation of proteins across membranes.
48501	signal recognition particle, plasma membrane targeting	C	A complex consisting of a protein and RNA component which binds the signal sequence of some proteins and facilitates their export to or across the plasma membrane.
48502	thiamine-transporting ATPase activity	F	Catalysis of the reaction: ATP + H2O + thiamine(out) = ADP + phosphate + thiamine(in).
48504	regulation of timing of animal organ formation	P	Any process that modulates the rate, frequency or extent of animal organ formation at a consistent predetermined time point during development.
48505	regulation of timing of cell differentiation	P	The process controlling the activation and/or rate at which relatively unspecialized cells acquire specialized features. Any process that modulates the rate, frequency or extent of the XXX at a consistent predetermined time point during its development.
48506	regulation of timing of meristematic phase transition	P	Any process that modulates the rate, frequency or extent of a change in identity of a meristem at a characteristic predetermined time point.
48507	meristem development	P	The process whose specific outcome is the progression of the meristem over time, from its formation to the mature structure.
48508	embryonic meristem development	P	The process whose specific outcome is the progression of the embryonic meristem over time, from its formation to the mature structure.
48509	regulation of meristem development	P	Any process that modulates the frequency, rate or extent of meristem development, the biological process whose specific outcome is the progression of the meristem over time, from its formation to the mature structure.
48510	regulation of timing of transition from vegetative to reproductive phase	P	The process controlling the point in time during development when a vegetative meristem will change its identity to become an inflorescence or floral meristem, and/or the rate at which the change occurs.
48511	rhythmic process	P	Any process pertinent to the generation and maintenance of rhythms in the physiology of an organism.
48512	circadian behavior	P	The specific behavior of an organism that recurs with a regularity of approximately 24 hours.
48513	animal organ development	P	Development of a tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.
48514	blood vessel morphogenesis	P	The process in which the anatomical structures of blood vessels are generated and organized. The blood vessel is the vasculature carrying blood.
48515	spermatid differentiation	P	The process whose specific outcome is the progression of a spermatid over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.
48518	positive regulation of biological process	P	Any process that activates or increases the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.
48519	negative regulation of biological process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.
48520	positive regulation of behavior	P	Any process that activates or increases the frequency, rate or extent of behavior, the internally coordinated responses (actions or inactions) of whole living organisms (individuals or groups) to internal or external stimuli.
48521	negative regulation of behavior	P	Any process that stops, prevents, or reduces the frequency, rate or extent of behavior, the internally coordinated responses (actions or inactions) of whole living organisms (individuals or groups) to internal or external stimuli.
48522	positive regulation of cellular process	P	Any process that activates or increases the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
48523	negative regulation of cellular process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
48524	positive regulation of viral process	P	Any process that activates or increases the frequency, rate or extent of a multi-organism process in which a virus is a participant.
48525	negative regulation of viral process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of a multi-organism process in which a virus is a participant.
48526	imaginal disc-derived wing expansion	P	The process of expanding or inflating the folded imaginal disc-derived pupal wing, and the adhering of the dorsal and ventral surfaces, to form the mature adult wing.
48527	lateral root development	P	The process whose specific outcome is the progression of the lateral root over time, from its formation to the mature structure. A lateral root is one formed from pericycle cells located on the xylem radius of the root, as opposed to the initiation of the main root from the embryo proper.
48528	post-embryonic root development	P	The process whose specific outcome is the progression of the post-embryonic root over time, from its formation to the mature structure.
48529	magnesium-protoporphyrin IX monomethyl ester (oxidative) cyclase activity	F	Catalysis of the reaction: magnesium protoporphyrin IX 13-monomethyl ester + 3 NADPH + 3 H+ + 3 O2 = divinylprotochlorophyllide + 3 NADP+ + 5 H2O.
48530	fruit morphogenesis	P	The process in which the anatomical structures of a fruit are generated and organized. A fruit is a reproductive body of a seed plant.
48531	beta-1,3-galactosyltransferase activity	F	Catalysis of the transfer of a galactose residue from a donor molecule to an oligosaccharide, forming a beta-1,3-linkage.
48532	anatomical structure arrangement	P	The process that gives rise to the configuration of the constituent parts of an anatomical structure. This process pertains to the physical shaping of a rudimentary structure. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome.
48533	sporocyte differentiation	P	The process in which a relatively unspecialized floral cell acquires the specialized features of a sporocyte. Sporocytes are the haploid spores of angiosperms. Once formed, they undergo meiotic divisions to form microspores and megaspores.
48534	hematopoietic or lymphoid organ development	P	The process whose specific outcome is the progression of any organ involved in hematopoiesis (also known as hemopoiesis) or lymphoid cell activation over time, from its formation to the mature structure. Such development includes differentiation of resident cell types (stromal cells) and of migratory cell types dependent on the unique microenvironment afforded by the organ for their proper differentiation.
48535	lymph node development	P	The process whose specific outcome is the progression of lymph nodes over time, from their formation to the mature structure. A lymph node is a round, oval, or bean shaped structure localized in clusters along the lymphatic vessels, with a distinct internal structure including specialized vasculature and B- and T-zones for the activation of lymphocytes.
48536	spleen development	P	The process whose specific outcome is the progression of the spleen over time, from its formation to the mature structure. The spleen is a large vascular lymphatic organ composed of white and red pulp, involved both in hemopoietic and immune system functions.
48537	mucosal-associated lymphoid tissue development	P	The process whose specific outcome is the progression of mucosal-associated lymphoid tissue over time, from its formation to the mature structure. Mucosal-associated lymphoid tissue is typically found as nodules associated with mucosal epithelia with distinct internal structures including B- and T-zones for the activation of lymphocytes.
48538	thymus development	P	The process whose specific outcome is the progression of the thymus over time, from its formation to the mature structure. The thymus is a symmetric bi-lobed organ involved primarily in the differentiation of immature to mature T cells, with unique vascular, nervous, epithelial, and lymphoid cell components.
48539	bone marrow development	P	The process whose specific outcome is the progression of the bone marrow over time, from its formation to the mature structure.
48540	bursa of Fabricius development	P	The process whose specific outcome is the progression of the bursa of Fabricius over time, from its formation to the mature structure. The bursa of Fabricius is an organ found in birds involved in B cell differentiation.
48541	Peyer's patch development	P	The process whose specific outcome is the progression of Peyer's patches over time, from their formation to the mature structure. Peyer's patches are typically found as nodules associated with gut epithelium with distinct internal structures including B- and T-zones for the activation of lymphocytes.
48542	lymph gland development	P	The process whose specific outcome is the progression of the lymph gland over time, from its formation to the mature structure. The lymph gland is one of the sites of hemocyte differentiation. It consists of three to six bilaterally paired lobes that are attached to the cardioblasts during larval stages, and it degenerates during pupal stages.
48543	phytochrome chromophore biosynthetic process	P	The chemical reactions and pathways resulting in the formation of the phytochrome chromophore. The phytochrome chromophore is a linear tetrapyrrolic prosthetic group covalently attached to the large soluble protein phytochrome. Light absorption by the phytochrome chromophore triggers photoconversion between two spectrally distinct forms of the photoreceptor: Pr, the red light absorbing form, and Pfr, the far red light absorbing form.
48544	recognition of pollen	P	The process, involving the sharing and interaction of the single locus incompatibility haplotypes, involved in the recognition or rejection of the self pollen by cells in the stigma. This process ensures out-breeding in certain plant species.
48545	response to steroid hormone	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a steroid hormone stimulus.
48546	digestive tract morphogenesis	P	The process in which the anatomical structures of the digestive tract are generated and organized. The digestive tract is the anatomical structure through which food passes and is processed.
48548	regulation of pinocytosis	P	Any process that modulates the frequency, rate or extent of pinocytosis. Pinocytosis is the process in which cells take in liquid material from their external environment; literally 'cell drinking'. Liquid is enclosed in vesicles, formed by invagination of the plasma membrane. These vesicles then move into the cell and pass their contents to endosomes.
48549	positive regulation of pinocytosis	P	Any process that activates, maintains or increases the rate of pinocytosis. Pinocytosis is the process in which cells take in liquid material from their external environment; literally 'cell drinking'. Liquid is enclosed in vesicles, formed by invagination of the plasma membrane. These vesicles then move into the cell and pass their contents to endosomes.
48550	negative regulation of pinocytosis	P	Any process that stops, prevents, or reduces the frequency, rate or extent of pinocytosis. Pinocytosis is the process in which cells take in liquid material from their external environment; literally 'cell drinking'. Liquid is enclosed in vesicles, formed by invagination of the plasma membrane. These vesicles then move into the cell and pass their contents to endosomes.
48555	generative cell nucleus	C	The nucleus of the generative cell, a cell contained within the pollen grain that will divide to produce two haploid sperm cells.
48556	microsporocyte nucleus	C	The nucleus of the microsporocyte. The microsporocyte is a diploid cell in which meiosis will occur, resulting in four microspores. A microspore is a spore that, in vascular plants, gives rise to a male gametophyte.
48557	embryonic digestive tract morphogenesis	P	The process in which the anatomical structures of the digestive tract are generated and organized during embryonic development. The digestive tract is the anatomical structure through which food passes and is processed.
48559	establishment of floral organ orientation	P	The process that determines the orientation of the floral organs with reference to the central axis of the flower.
48560	establishment of anatomical structure orientation	P	The process that determines the orientation of an anatomical structure with reference to an axis.
48561	establishment of animal organ orientation	P	The process that determines the orientation of an animal organ or tissue with reference to an axis.
48562	embryonic organ morphogenesis	P	Morphogenesis, during the embryonic phase, of a tissue or tissues that work together to perform a specific function or functions. Morphogenesis is the process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.
48563	post-embryonic animal organ morphogenesis	P	Morphogenesis, during the post-embryonic phase, of an animal tissue or tissues that work together to perform a specific function or functions. Morphogenesis pertains to process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.
48564	photosystem I assembly	P	The aggregation, arrangement and bonding together of a set of components to form a photosystem I complex on the thylakoid membrane.
48565	digestive tract development	P	The process whose specific outcome is the progression of the digestive tract over time, from its formation to the mature structure. The digestive tract is the anatomical structure through which food passes and is processed.
48566	embryonic digestive tract development	P	The process whose specific outcome is the progression of the gut over time, from its formation to the mature structure during embryonic development. The gut is the region of the digestive tract extending from the beginning of the intestines to the anus.
48567	ectodermal digestive tract morphogenesis	P	The process in which the anatomical structures of the ectodermal digestive tract are generated and organized. The ectodermal digestive tract includes those portions of the digestive tract that are derived from ectoderm.
48568	embryonic organ development	P	Development, taking place during the embryonic phase, of a tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.
48569	post-embryonic animal organ development	P	Development, taking place during the post-embryonic phase of an animal tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.
48570	notochord morphogenesis	P	The process in which the anatomical structures of the notochord are generated and organized. The notochord is a mesoderm-derived structure located ventral of the developing nerve cord. In vertebrates, the notochord serves as a core around which other mesodermal cells form the vertebrae. In the most primitive chordates, which lack vertebrae, the notochord persists as a substitute for a vertebral column.
48571	long-day photoperiodism	P	Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a day length that exceeds a particular duration known as the 'critical day length'. The critical day length varies between species. Although the term long-day is used, most species actually respond to the duration of the night, so that the response will occur when a period of darkness falls short of the number of hours defined by 24 hours minus the critical day length.
48572	short-day photoperiodism	P	Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a day length that falls short of a particular duration known as the 'critical day length'. The critical day length varies between species. Although the term short-day is used, most species actually respond to the duration of the night, so that the response will occur when a period of darkness exceeds the number of hours defined by 24 hours minus the critical day length.
48573	photoperiodism, flowering	P	A change from the vegetative to the reproductive phase as a result of detection of, or exposure to, a period of light or dark of a given length. The length of the period of light or dark required to initiate the change is set relative to a particular duration known as the 'critical day length'. The critical day length varies between species.
48574	long-day photoperiodism, flowering	P	A change from the vegetative to the reproductive phase as a result of detection of, or exposure to, a period of light that exceeds the critical day length. The critical day length varies between species. Although the term is long-day is used, most species actually respond to the duration of the night, so that the response will occur when a period of darkness falls short of the number of hours defined by 24 minus the critical day length.
48575	short-day photoperiodism, flowering	P	A change from vegetative to reproductive phase as a result of detection of, or exposure to, a period of light that falls short of the critical day length. The critical day length varies between species. Although the term is short-day is used, most species actually respond to the duration of the night, so that the response will occur when a period of darkness exceeds the number of hours defined by 24 minus the critical day length.
48576	positive regulation of short-day photoperiodism, flowering	P	Any process that activates, maintains or increases short-day photoperiodism, where the response associated with the photoperiodism is flowering. Flowering is defined by the switch from the vegetative to the reproductive phase.
48577	negative regulation of short-day photoperiodism, flowering	P	Any process that stops, prevents or reduces short-day photoperiodism, where the response associated with the photoperiodism is flowering. Flowering is defined by the switch from the vegetative to the reproductive phase.
48578	positive regulation of long-day photoperiodism, flowering	P	Any process that activates, maintains or increases long-day photoperiodism, where the response associated with the photoperiodism is flowering. Flowering is defined by the switch from the vegetative to the reproductive phase.
48579	negative regulation of long-day photoperiodism, flowering	P	Any process that stops, prevents or reduces long-day photoperiodism, where the response associated with the photoperiodism is flowering. Flowering is defined by the switch from the vegetative to the reproductive phase.
48580	regulation of post-embryonic development	P	Any process that modulates the frequency, rate or extent of post-embryonic development. Post-embryonic development is defined as the process whose specific outcome is the progression of the organism over time, from the completion of embryonic development to the mature structure.
48581	negative regulation of post-embryonic development	P	Any process that stops, prevents, or reduces the frequency, rate or extent of post-embryonic development. Post-embryonic development is defined as the process whose specific outcome is the progression of the organism over time, from the completion of embryonic development to the mature structure.
48582	positive regulation of post-embryonic development	P	Any process that activates or increases the frequency, rate or extent of post-embryonic development. Post-embryonic development is defined as the process whose specific outcome is the progression of the organism over time, from the completion of embryonic development to the mature structure.
48583	regulation of response to stimulus	P	Any process that modulates the frequency, rate or extent of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.
48584	positive regulation of response to stimulus	P	Any process that activates, maintains or increases the rate of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.
48585	negative regulation of response to stimulus	P	Any process that stops, prevents, or reduces the frequency, rate or extent of a response to a stimulus. Response to stimulus is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus.
48586	regulation of long-day photoperiodism, flowering	P	Any process that modulates the frequency, rate or extent of long-day photoperiodism, where the response associated with the photoperiodism is flowering. Flowering is defined by the switch from the vegetative to the reproductive phase.
48587	regulation of short-day photoperiodism, flowering	P	Any process that modulates the frequency, rate or extent of short-day photoperiodism, where the response associated with the photoperiodism is flowering. Flowering is defined by the switch from the vegetative to the reproductive phase.
48588	developmental cell growth	P	The growth of a cell, where growth contributes to the progression of the cell over time from one condition to another.
48589	developmental growth	P	The increase in size or mass of an entire organism, a part of an organism or a cell, where the increase in size or mass has the specific outcome of the progression of the organism over time from one condition to another.
48592	eye morphogenesis	P	The process in which the anatomical structures of the eye are generated and organized.
48593	camera-type eye morphogenesis	P	The process in which the anatomical structures of the eye are generated and organized. The camera-type eye is an organ of sight that receives light through an aperture and focuses it through a lens, projecting it on a photoreceptor field.
48596	embryonic camera-type eye morphogenesis	P	The process in which the anatomical structures of the eye are generated and organized during embryonic development.
48597	post-embryonic camera-type eye morphogenesis	P	The process in which the anatomical structures of the eye are generated and organized during post-embryonic development.
48598	embryonic morphogenesis	P	The process in which anatomical structures are generated and organized during the embryonic phase. The embryonic phase begins with zygote formation. The end of the embryonic phase is organism-specific. For example, it would be at birth for mammals, larval hatching for insects and seed dormancy in plants.
48599	oocyte development	P	The process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell.
48600	oocyte fate commitment	P	The process in which the developmental fate of a cell becomes restricted such that it will develop into an oocyte.
48601	oocyte morphogenesis	P	The process in which the structures of an oocyte are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of an oocyte.
48608	reproductive structure development	P	The reproductive developmental process whose specific outcome is the progression of structures that will be used in the process of creating new individuals from one or more parents, from their formation to the mature structures.
48609	multicellular organismal reproductive process	P	The process, occurring above the cellular level, that is pertinent to the reproductive function of a multicellular organism. This includes the integrated processes at the level of tissues and organs.
48611	embryonic ectodermal digestive tract development	P	The process, occurring during the embryonic phase, whose specific outcome is the progression of the ectodermal gut over time, from its formation to the mature structure.
48612	post-embryonic ectodermal digestive tract development	P	The process, occurring during the post-embryonic phase, whose specific outcome is the progression of the ectodermal gut over time, from its formation to the mature structure.
48613	embryonic ectodermal digestive tract morphogenesis	P	The process, occurring during the embryonic phase, by which the anatomical structures of the ectodermal digestive tract are generated and organized.
48614	post-embryonic ectodermal digestive tract morphogenesis	P	The process, occurring during the post-embryonic phase, by which the anatomical structures of the ectodermal gut are generated and organized.
48615	embryonic anterior midgut (ectodermal) morphogenesis	P	The process in which the anatomical structures of the anterior midgut (ectodermal) are generated and organized, during the embryonic phase.
48616	post-embryonic anterior midgut (ectodermal) morphogenesis	P	The process in which the anatomical structures of the anterior midgut (ectodermal) are generated and organized, during the post-embryonic phase.
48617	embryonic foregut morphogenesis	P	The process in which the anatomical structures of the foregut are generated and organized, during the embryonic phase.
48618	post-embryonic foregut morphogenesis	P	The process in which the anatomical structures of the foregut are generated and organized, during the post-embryonic phase.
48619	embryonic hindgut morphogenesis	P	The process in which the anatomical structures of the hindgut are generated and organized, during the embryonic phase.
48620	post-embryonic hindgut morphogenesis	P	The process in which the anatomical structures of the hindgut are generated and organized, during the post-embryonic phase.
48621	post-embryonic digestive tract morphogenesis	P	The process, occurring during the post-embryonic phase, by which the anatomical structures of the digestive tract are generated and organized. The digestive tract is the anatomical structure through which food passes and is processed.
48623	seed germination on parent plant	P	The process in which a seed germinates before being shed from the parent plant.
48624	plantlet formation on parent plant	P	The process in which a new plantlet develops from a meristem on the plant body. As part of this process, when the plantlet is large enough to live independently, the physical connection between the new plantlet and the main plant is severed.
48625	myoblast fate commitment	P	The process in which the developmental fate of a cell becomes restricted such that it will develop into a myoblast. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.
48626	myoblast fate specification	P	The process in which a cell becomes capable of differentiating autonomously into a myoblast in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.
48627	myoblast development	P	The process whose specific outcome is the progression of the myoblast over time, from its formation to the mature structure. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.
48628	myoblast maturation	P	A developmental process, independent of morphogenetic (shape) change, that is required for a myoblast to attain its fully functional state. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.
48629	trichome patterning	P	The regionalization process of establishing the non-random spatial arrangement of trichomes on the surface and margin of a leaf. Process involves signaling between adjacent epidermal cells that results in differentiation of some epidermal cells into trichomes.
48630	skeletal muscle tissue growth	P	The increase in size or mass of a skeletal muscle. This may be due to a change in the fiber number or size.
48631	regulation of skeletal muscle tissue growth	P	Any process that modulates the frequency, rate or extent of skeletal muscle growth.
48632	negative regulation of skeletal muscle tissue growth	P	Any process that stops, prevents, or reduces the frequency, rate or extent of skeletal muscle growth.
48633	positive regulation of skeletal muscle tissue growth	P	Any process that activates, maintains or increases the rate of skeletal muscle growth.
48634	regulation of muscle organ development	P	Any process that modulates the frequency, rate or extent of muscle development.
48635	negative regulation of muscle organ development	P	Any process that stops, prevents, or reduces the frequency, rate or extent of muscle development.
48636	positive regulation of muscle organ development	P	Any process that activates, maintains or increases the rate of muscle development.
48638	regulation of developmental growth	P	Any process that modulates the frequency, rate or extent of developmental growth.
48639	positive regulation of developmental growth	P	Any process that activates, maintains or increases the rate of developmental growth.
48640	negative regulation of developmental growth	P	Any process that stops, prevents, or reduces the frequency, rate or extent of developmental growth.
48641	regulation of skeletal muscle tissue development	P	Any process that modulates the frequency, rate or extent of skeletal muscle tissue development.
48642	negative regulation of skeletal muscle tissue development	P	Any process that stops, prevents, or reduces the frequency, rate or extent of skeletal muscle tissue development.
48643	positive regulation of skeletal muscle tissue development	P	Any process that activates, maintains or increases the rate of skeletal muscle tissue development.
48644	muscle organ morphogenesis	P	The process in which the anatomical structures of muscle are generated and organized.
48645	animal organ formation	P	The process pertaining to the initial formation of an animal organ from unspecified parts. The process begins with the specific processes that contribute to the appearance of the discrete structure, such as inductive events, and ends when the structural rudiment of the organ is recognizable, such as a condensation of mesenchymal cells into the organ rudiment. Organs are a natural part or structure in an animal or a plant, capable of performing some special action (termed its function), which is essential to the life or well-being of the whole. The heart and lungs are organs of animals, and the petal and leaf are organs of plants. In animals the organs are generally made up of several tissues, one of which usually predominates, and determines the principal function of the organ.
48646	anatomical structure formation involved in morphogenesis	P	The developmental process pertaining to the initial formation of an anatomical structure from unspecified parts. This process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the structural rudiment is recognizable. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome.
48647	polyphenic determination	P	The process in which individuals that have the potential to develop any of several possible distinct developmental paths have their individual developmental fates determined in response to environmental and/or genetic cues.
48648	caste determination	P	The process in which individuals, having the potential to develop any of several distinct developmental paths, have their individual developmental fate determined in response to environmental and/or genetic cues. Individuals with distinct developmental fates perform different functions in a colony of social insects.
48649	caste determination, influence by genetic factors	P	The process in which individuals, having the potential to develop any of several distinct developmental paths, have their individual developmental fate determined in response to genetic cues. Individuals with distinct developmental fates perform different functions in a colony of social insects.
48650	caste determination, influence by environmental factors	P	The process in which individuals, having the potential to develop any of several distinct developmental paths, have their individual developmental fate determined in response to environmental cues. Individuals with distinct developmental fates perform different functions in a colony of social insects.
48651	polyphenic determination, influence by environmental factors	P	The process in which individuals that have the potential to develop any of several possible distinct developmental paths have their individual developmental fates determined in response to environmental cues.
48652	polyphenic determination, influence by genetic factors	P	The process in which individuals that have the potential to develop any of several possible distinct developmental paths have their individual developmental fates determined in response to genetic cues.
48653	anther development	P	The process whose specific outcome is the progression of the anther over time, from its formation to the mature structure.
48654	anther morphogenesis	P	The process in which the anatomical structures of the anther are generated and organized.
48655	anther wall tapetum morphogenesis	P	The process in which the anatomical structures of the anther wall tapetum are generated and organized. The anther wall tapetum is a layer of cells that provides a source of nutrition for the pollen grains as they mature.
48656	anther wall tapetum formation	P	The process that gives rise to the anther wall tapetum. This process pertains to the initial formation of a structure from unspecified parts. The anther wall tapetum is a layer of cells that provides a source of nutrition for the pollen grains as they mature.
48657	anther wall tapetum cell differentiation	P	The process in which a relatively unspecialized cell acquires specialized features of an anther cell wall tapetum cell. The tapetum is a layer of cells that provides a source of nutrition for the pollen grains as they mature.
48658	anther wall tapetum development	P	The process whose specific outcome is the progression of the anther wall tapetum over time, from its formation to the mature structure.
48659	smooth muscle cell proliferation	P	The multiplication or reproduction of smooth muscle cells, resulting in the expansion of a cell population.
48660	regulation of smooth muscle cell proliferation	P	Any process that modulates the frequency, rate or extent of smooth muscle cell proliferation.
48661	positive regulation of smooth muscle cell proliferation	P	Any process that activates or increases the rate or extent of smooth muscle cell proliferation.
48662	negative regulation of smooth muscle cell proliferation	P	Any process that stops, prevents or reduces the rate or extent of smooth muscle cell proliferation.
48663	neuron fate commitment	P	The process in which the developmental fate of a cell becomes restricted such that it will develop into a neuron.
48664	neuron fate determination	P	The process in which a cell becomes capable of differentiating autonomously into a neuron regardless of its environment; upon determination, the cell fate cannot be reversed.
48665	neuron fate specification	P	The process in which a cell becomes capable of differentiating autonomously into a neuron in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed.
48666	neuron development	P	The process whose specific outcome is the progression of a neuron over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.
48667	cell morphogenesis involved in neuron differentiation	P	The process in which the structures of a neuron are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a neuron.
48668	collateral sprouting	P	The process in which outgrowths develop from the shafts of existing axons.
48669	collateral sprouting in absence of injury	P	The process in which outgrowths develop from the axons of intact undamaged neurons.
48670	regulation of collateral sprouting	P	Any process that modulates the frequency, rate or extent of collateral sprouting.
48671	negative regulation of collateral sprouting	P	Any process that stops, prevents, or reduces the frequency, rate or extent of collateral sprouting.
48672	positive regulation of collateral sprouting	P	Any process that activates or increases the frequency, rate or extent of collateral sprouting.
48673	collateral sprouting of intact axon in response to injury	P	The process in which outgrowths develop from the axons of intact undamaged neurons as a result of injury to an axon. The collateral sprouts typically appear from undamaged axons in a tissue which has had part of its nerve supply removed, and they can often innervate successfully any cells that have lost some or all of their original synaptic input.
48674	collateral sprouting of injured axon	P	The process resulting in reformation of a growth cone by the tip of an injured axon, or in collateral sprouting of the axon. Collateral sprouting is the process in which outgrowths develop from the shafts of existing axons.
48675	axon extension	P	Long distance growth of a single axon process involved in cellular development.
48677	axon extension involved in regeneration	P	Long distance growth of a single axon process involved in regeneration of the neuron.
48678	response to axon injury	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an axon injury stimulus.
48679	regulation of axon regeneration	P	Any process that modulates the frequency, rate or extent of axon regeneration.
48680	positive regulation of axon regeneration	P	Any process that activates, maintains or increases the rate of axon regeneration.
48681	negative regulation of axon regeneration	P	Any process that stops, prevents, or reduces the frequency, rate or extent of axon regeneration.
48682	sprouting of injured axon	P	The process involved in sprouting of an injured axon.
48683	regulation of collateral sprouting of intact axon in response to injury	P	Any process that modulates the frequency, rate or extent of collateral sprouting of an intact axon as a result of injury to an axon.
48684	positive regulation of collateral sprouting of intact axon in response to injury	P	Any process that activates, maintains or increases the rate of collateral sprouting of an intact axon as a result of injury to an axon.
48685	negative regulation of collateral sprouting of intact axon in response to injury	P	Any process that stops, prevents, or reduces the frequency, rate or extent of collateral sprouting of an intact axon as a result of injury to an axon.
48686	regulation of sprouting of injured axon	P	Any process that modulates the frequency, rate or extent of sprouting of an injured axon.
48687	positive regulation of sprouting of injured axon	P	Any process that activates, maintains or increases the rate of sprouting of an injured axon.
48688	negative regulation of sprouting of injured axon	P	Any process that stops, prevents, or reduces the frequency, rate or extent of sprouting of an injured axon.
48689	formation of growth cone in injured axon	P	The formation of a growth cone in an injured axon.
48690	regulation of axon extension involved in regeneration	P	Any process that modulates the frequency, rate or extent of axon extension involved in regeneration.
48691	positive regulation of axon extension involved in regeneration	P	Any process that activates, maintains or increases the rate of axon extension involved in regeneration.
48692	negative regulation of axon extension involved in regeneration	P	Any process that stops, prevents, or reduces the frequency, rate or extent of axon extension involved in regeneration.
48693	regulation of collateral sprouting of injured axon	P	Any process that modulates the frequency, rate or extent of collateral sprouting of an injured axon.
48694	positive regulation of collateral sprouting of injured axon	P	Any process that activates, maintains or increases the rate of collateral sprouting of an injured axon.
48695	negative regulation of collateral sprouting of injured axon	P	Any process that stops, prevents, or reduces the frequency, rate or extent of collateral sprouting of an injured axon.
48696	regulation of collateral sprouting in absence of injury	P	Any process that modulates the frequency, rate or extent of collateral sprouting in the absence of injury.
48697	positive regulation of collateral sprouting in absence of injury	P	Any process that activates or increases the frequency, rate or extent of collateral sprouting in the absence of injury.
48698	negative regulation of collateral sprouting in absence of injury	P	Any process that stops, prevents, or reduces the frequency, rate or extent of collateral sprouting in the absence of injury.
48699	generation of neurons	P	The process in which nerve cells are generated. This includes the production of neuroblasts and their differentiation into neurons.
48700	acquisition of desiccation tolerance in seed	P	The process in which a seed acquires tolerance to severe drying, before entering into a dry, either dormant or quiescent state.
48701	embryonic cranial skeleton morphogenesis	P	The process in which the anatomical structures of the cranial skeleton are generated and organized during the embryonic phase.
48702	embryonic neurocranium morphogenesis	P	The process in which the anatomical structures of the neurocranium are generated and organized during the embryonic phase. The neurocranium is the portion of the vertebrate skull surrounding the brain.
48703	embryonic viscerocranium morphogenesis	P	The process in which the anatomical structures of the viscerocranium are generated and organized during the embryonic phase. The viscerocranium is the part of the skull comprising the facial bones.
48704	embryonic skeletal system morphogenesis	P	The process in which the anatomical structures of the skeleton are generated and organized during the embryonic phase.
48705	skeletal system morphogenesis	P	The process in which the anatomical structures of the skeleton are generated and organized.
48706	embryonic skeletal system development	P	The process, occurring during the embryonic phase, whose specific outcome is the progression of the skeleton over time, from its formation to the mature structure.
48707	instar larval or pupal morphogenesis	P	The process, occurring during instar larval or pupal development, by which anatomical structures are generated and organized.
48708	astrocyte differentiation	P	The process in which a relatively unspecialized cell acquires the specialized features of an astrocyte. An astrocyte is the most abundant type of glial cell. Astrocytes provide support for neurons and regulate the environment in which they function.
48709	oligodendrocyte differentiation	P	The process in which a relatively unspecialized cell acquires the specialized features of an oligodendrocyte. An oligodendrocyte is a type of glial cell involved in myelinating the axons of neurons in the central nervous system.
48710	regulation of astrocyte differentiation	P	Any process that modulates the frequency, rate or extent of astrocyte differentiation.
48711	positive regulation of astrocyte differentiation	P	Any process that activates or increases the frequency, rate or extent of astrocyte differentiation.
48712	negative regulation of astrocyte differentiation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of astrocyte differentiation.
48713	regulation of oligodendrocyte differentiation	P	Any process that modulates the frequency, rate or extent of oligodendrocyte differentiation.
48714	positive regulation of oligodendrocyte differentiation	P	Any process that activates or increases the frequency, rate or extent of oligodendrocyte differentiation.
48715	negative regulation of oligodendrocyte differentiation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of oligodendrocyte differentiation.
48716	labrum morphogenesis	P	The process in which the anatomical structures of labrum are generated and organized.
48717	anterior cibarial plate morphogenesis	P	The process in which the anatomical structures of the anterior cibarial plate are generated and organized.
48718	cibarial fish-trap bristle morphogenesis	P	The process in which the anatomical structures of a cibarial fish-trap bristle are generated and organized. A cibarial fish-trap bristle is a sensory bristle on the anterior plate of the cibarium.
48719	epistomal sclerite morphogenesis	P	The process in which the anatomical structures of the epistomal sclerite are generated and organized.
48720	posterior cibarial plate morphogenesis	P	The process in which the anatomical structures of the posterior cibarial plate are generated and organized.
48721	clypeus morphogenesis	P	The process in which the anatomical structures of the clypeus are generated and organized.
48722	anterior cibarial plate development	P	The process whose specific outcome is the progression of the anterior cibarial plate over time, from their formation to the mature structure.
48723	clypeus development	P	The process whose specific outcome is the progression of the clypeus over time, from its formation to the mature structure. The clypeus is the shield-shaped plate on an insect's head.
48724	epistomal sclerite development	P	The process whose specific outcome is the progression of the epistomal sclerite over time, from its formation to the mature structure.
48725	cibarial fish-trap bristle development	P	The process whose specific outcome is the progression of the cibarial fish-trap bristle over time, from its formation to the mature structure. A cibarial fish-trap bristle is a sensory bristle on the anterior plate of the cibarium.
48726	labrum development	P	The process whose specific outcome is the progression of the labrum over time, from its formation to the mature structure.
48727	posterior cibarial plate development	P	The process whose specific outcome is the progression of the posterior cibarial plate over time, from its formation to the mature structure.
48728	proboscis development	P	The process whose specific outcome is the progression of the proboscis over time, from its formation to the mature structure.
48729	tissue morphogenesis	P	The process in which the anatomical structures of a tissue are generated and organized.
48730	epidermis morphogenesis	P	The process in which the anatomical structures of the epidermis are generated and organized. The epidermis is the outer epithelial layer of an animal, it may be a single layer that produces an extracellular material (e.g. the cuticle of arthropods) or a complex stratified squamous epithelium, as in the case of many vertebrate species.
48731	system development	P	The process whose specific outcome is the progression of an organismal system over time, from its formation to the mature structure. A system is a regularly interacting or interdependent group of organs or tissues that work together to carry out a given biological process.
48732	gland development	P	The process whose specific outcome is the progression of a gland over time, from its formation to the mature structure. A gland is an organ specialised for secretion.
48733	sebaceous gland development	P	The process whose specific outcome is the progression of the sebaceous gland over time, from its formation to the mature structure.
48734	proboscis morphogenesis	P	The process in which the anatomical structures of the proboscis are generated and organized. The proboscis is the trunk-like extension of the mouthparts on the adult head.
48735	haltere morphogenesis	P	The process in which the anatomical structures of a haltere are generated and organized.
48736	appendage development	P	The process whose specific outcome is the progression of an appendage over time, from its formation to the mature structure. An appendage is an organ or part that is attached to the trunk of an organism, such as a limb or a branch.
48737	imaginal disc-derived appendage development	P	The process whose specific outcome is the progression of an appendage over time, from its formation in the imaginal disc to the mature structure. An appendage is an organ or part that is attached to the trunk of an organism.
48738	cardiac muscle tissue development	P	The process whose specific outcome is the progression of cardiac muscle over time, from its formation to the mature structure.
48739	cardiac muscle fiber development	P	The process whose specific outcome is the progression of cardiac muscle fiber over time, from its formation to the mature structure.
48741	skeletal muscle fiber development	P	The process whose specific outcome is the progression of the skeletal muscle fiber over time, from its formation to the mature structure. Muscle fibers are formed by the maturation of myotubes. They can be classed as slow, intermediate/fast or fast.
48742	regulation of skeletal muscle fiber development	P	Any process that modulates the frequency, rate or extent of skeletal muscle fiber development. Muscle fibers are formed by the maturation of myotubes. They can be classed as slow, intermediate/fast or fast.
48743	positive regulation of skeletal muscle fiber development	P	Any process that activates, maintains or increases the rate of skeletal muscle fiber development. Muscle fibers are formed by the maturation of myotubes. They can be classed as slow, intermediate/fast or fast.
48744	negative regulation of skeletal muscle fiber development	P	Any process that stops, prevents, or reduces the frequency, rate or extent of skeletal muscle fiber development. Muscle fibers are formed by the maturation of myotubes. They can be classed as slow, intermediate/fast or fast.
48745	smooth muscle tissue development	P	The process whose specific outcome is the progression of smooth muscle over time, from its formation to the mature structure.
48747	muscle fiber development	P	The process whose specific outcome is the progression of the muscle fiber over time, from its formation to the mature structure. In skeletal muscle, fibers are formed by the maturation of myotubes. They can be classed as slow, intermediate/fast or fast.
48749	compound eye development	P	The process whose specific outcome is the progression of the compound eye over time, from its formation to the mature structure. The compound eye is an organ of sight that contains multiple repeating units, often arranged hexagonally. Each unit has its own lens and photoreceptor cell(s) and can generate either a single pixelated image or multiple images, per eye.
48750	compound eye corneal lens morphogenesis	P	The process in which the anatomical structures of the compound eye corneal lens are generated and organized.
48752	semicircular canal morphogenesis	P	The process in which the anatomical structures of the semicircular canals are generated and organized.
48753	pigment granule organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a pigment granule.
48754	branching morphogenesis of an epithelial tube	P	The process in which the anatomical structures of branches in an epithelial tube are generated and organized. A tube is a long hollow cylinder.
48755	branching morphogenesis of a nerve	P	The process in which the anatomical structures of branches in a nerve are generated and organized. This term refers to an anatomical structure (nerve) not a cell (neuron).
48756	sieve cell differentiation	P	The process in which a relatively unspecialized cell acquires specialized features of a sieve cell. A sieve cell is a type of sieve element that has relatively undifferentiated sieve areas (with narrow pores). The sieve areas are rather uniform in structure on all walls; that is, there are no sieve plates. Typical of gymnosperms and lower vascular plants. The sieve element is the cell in the phloem tissue concerned with mainly longitudinal conduction of food materials.
48757	pigment granule maturation	P	Steps required to form a membrane-bounded organelle into a pigment granule containing pigment. Maturation is a developmental process, independent of morphogenetic (shape) change, that is required for a cell or structure to attain its fully functional state.
48758	companion cell differentiation	P	The process in which a relatively unspecialized cell acquires specialized features of a companion cell. The companion cell is the specialized parenchyma cell associated with a sieve-tube member in angiosperm phloem and arising from the same mother cell as the sieve-tube member.
48759	xylem vessel member cell differentiation	P	The process in which a relatively unspecialized cell acquires specialized features of a vessel member cell. A vessel member cell is one of the components of a vessel in the xylem. It is a dead cell with the wall between adjacent members being variously perforated and the walls that persist variously thickened.
48760	plant parenchymal cell differentiation	P	The process in which a relatively unspecialized cell acquires specialized features of a parenchymal cell. Parenchymal cells are the most abundant and versatile cells in plants. They have very few distinguishing characteristics and botanists classify them as any cell type that cannot be assigned to any other structural or functional class. They can redifferentiate and dedifferentiate and are involved in storage, basic metabolism and other processes. The cells are polyhedral, typically with thin, non-lignified cellulose cell walls and nucleate living protoplasm. They vary in size, form, and wall structure.
48761	collenchyma cell differentiation	P	The process in which a relatively unspecialized cell acquires specialized features of a collenchyma cell. This is a plant cell in which the primary cell walls are unevenly thickened, with most thickening occurring at the cell corners. Cells are living and able to grow, they are elongated, and lignin and secondary walls absent. Collenchyma cells make up collenchyma tissue which acts as a supporting tissue in growing shoots, leaves and petioles. This tissue is often arranged in cortical ribs, as seen prominently in celery and rhubarb petioles.
48762	mesenchymal cell differentiation	P	The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal cell. A mesenchymal cell is a loosely associated cell that is part of the connective tissue in an organism. Mesenchymal cells give rise to more mature connective tissue cell types.
48763	calcium-induced calcium release activity	F	Enables transmembrane transfer of calcium ions from an intracellular store to the cytosol on induction by increased calcium concentration.
48764	trichoblast maturation	P	A developmental process, independent of morphogenetic (shape) change, that is required for a trichoblast cell to attain its fully functional state.
48765	root hair cell differentiation	P	The process in which a relatively unspecialized cell acquires specialized features of a root hair cell.
48766	root hair initiation	P	The process in which a protrusion or bulge is formed at the site of plant root hair outgrowth.
48767	root hair elongation	P	The process in which the root hair grows longer.
48768	root hair cell tip growth	P	Localized growth of a plant root hair tip by extension of the cell wall.
48769	sarcomerogenesis	P	The process in which sarcomeres are added in series within a fiber.
48770	pigment granule	C	A small, subcellular membrane-bounded vesicle containing pigment and/or pigment precursor molecules. Pigment granule biogenesis is poorly understood, as pigment granules are derived from multiple sources including the endoplasmic reticulum, coated vesicles, lysosomes, and endosomes.
48771	tissue remodeling	P	The reorganization or renovation of existing tissues. This process can either change the characteristics of a tissue such as in blood vessel remodeling, or result in the dynamic equilibrium of a tissue such as in bone remodeling.
48772	leucophore differentiation	P	The process in which a relatively unspecialized cell acquires the specialized features of a leucophore cell. Leucophores are pigment cells derived from the neural crest. They contain uric acid or other purine crystals, deposited in stacks called leucosomes. This gives them a white appearance.
48773	erythrophore differentiation	P	The process in which a relatively unspecialized cell acquires the specialized features of an erythrophore cell. Erythrophores are pigment cells derived from the neural crest. They contain pteridine and/or carotenoid pigments in structures called pterinosomes or erythrosomes. This gives them an orange to red appearance.
48774	cyanophore differentiation	P	The process in which a relatively unspecialized cell acquires the specialized features of a cyanophore cell. Cyanophores are pigment cells derived from the neural crest. They contain a blue pigment of unknown chemical composition. The pigment is stored in fibrous organelles termed cyanosomes.
48775	regulation of leucophore differentiation	P	Any process that modulates the frequency, rate or extent of leucophore differentiation.
48776	negative regulation of leucophore differentiation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of leucophore differentiation.
48777	positive regulation of leucophore differentiation	P	Any process that activates or increases the frequency, rate or extent of leucophore differentiation.
48778	regulation of erythrophore differentiation	P	Any process that modulates the frequency, rate or extent of erythrophore differentiation.
48779	negative regulation of erythrophore differentiation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of erythrophore differentiation.
48780	positive regulation of erythrophore differentiation	P	Any process that activates or increases the frequency, rate or extent of erythrophore differentiation.
48781	regulation of cyanophore differentiation	P	Any process that modulates the frequency, rate or extent of cyanophore differentiation.
48782	negative regulation of cyanophore differentiation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of cyanophore differentiation.
48783	positive regulation of cyanophore differentiation	P	Any process that activates or increases the frequency, rate or extent of cyanophore differentiation.
48784	pigment biosynthetic process involved in pigment granule maturation	P	The chemical reactions and pathways resulting in the formation of a pigment, contributing to the process in which a membrane-bounded organelle develops into a pigment granule. Maturation is a developmental process, independent of morphogenetic (shape) change, that is required for a cell or structure to attain its fully functional state.
48785	hatching gland development	P	The process whose specific outcome is the progression of the hatching gland over time, from its formation to the mature structure. The cells of the hatching gland contain enzymes responsible for solubilization of the egg chorion, facilitating the hatching process.
48786	presynaptic active zone	C	A specialized region of the plasma membrane and cell cortex of a presynaptic neuron; encompasses a region of the plasma membrane where synaptic vesicles dock and fuse, and a specialized cortical cytoskeletal matrix.
48787	presynaptic active zone membrane	C	The membrane portion of the presynaptic active zone; it is the site where docking and fusion of synaptic vesicles occurs for the release of neurotransmitters.
48788	cytoskeleton of presynaptic active zone	C	The specialized cytoskeletal matrix of the presynaptic active zone. It has specialized functions in organizing synaptic events such as immobilisation or translocation of synaptic vesicles, and assembling active zone components. It is believed to form a molecular scaffold that organizes neurotransmitter release sites.
48789	cytoskeletal matrix organization at active zone	P	The assembly and arrangement of cytomatrix proteins to form complexes in the cell cortex beneath the active zone, i.e. just beneath the presynaptic plasma membrane.
48790	maintenance of presynaptic active zone structure	P	A process which maintains the organization and the arrangement of proteins at the active zone to ensure the fusion and docking of vesicles and the release of neurotransmitters.
48791	calcium ion-regulated exocytosis of neurotransmitter	P	The release of a neurotransmitter into the synaptic cleft by exocytosis of synaptic vesicles, where the release step is dependent on a rise in cytosolic calcium ion levels.
48792	spontaneous exocytosis of neurotransmitter	P	The release of a neurotransmitter into the synaptic cleft, where the release step is independent of the presence of calcium ions (Ca2+). The neurotransmitter is contained within a membrane-bounded vesicle, and is released by fusion of the vesicle with the presynaptic plasma membrane of a nerve cell.
48793	pronephros development	P	The process whose specific outcome is the progression of the pronephros over time, from its formation to the mature structure. In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensable for larval life.
48794	swim bladder development	P	The process whose specific outcome is the progression of the swim bladder over time, from its formation to the mature structure. The swim bladder is used by some fishes to maintain buoyancy and may function in addition as a sound producing organ, a sound receptor, and a respiratory organ.
48795	swim bladder morphogenesis	P	The process in which the anatomical structure of the swim bladder is generated and organized. The swim bladder is used by some fishes to maintain buoyancy and may function in addition as a sound producing organ, a sound receptor, and a respiratory organ.
48796	swim bladder maturation	P	A developmental process, independent of morphogenetic (shape) change, that is required for a swim bladder to attain its fully functional state. The swim bladder is used by some fishes to maintain buoyancy and may function in addition as a sound producing organ, a sound receptor, and a respiratory organ.
48797	swim bladder formation	P	The process that gives rise to the swim bladder. This process pertains to the initial formation of a structure from unspecified parts. The swim bladder is used by some fishes to maintain buoyancy and may function in addition as a sound producing organ, a sound receptor, and a respiratory organ.
48798	swim bladder inflation	P	The expansion of the swim bladder by trapped gases. The swim bladder is used by some fishes to maintain buoyancy and may function in addition as a sound producing organ, a sound receptor, and a respiratory organ.
48799	animal organ maturation	P	A developmental process, independent of morphogenetic (shape) change, that is required for an animal organ to attain its fully functional state. An organ is a tissue or set of tissues that work together to perform a specific function or functions.
48800	antennal morphogenesis	P	The process in which the anatomical structures of the antenna are generated and organized.
48801	antennal joint morphogenesis	P	The process in which the anatomical structures of the antennal joint are generated and organized.
48802	notum morphogenesis	P	The process in which the anatomical structures of the dorsal part of the body are generated and organized.
48803	imaginal disc-derived male genitalia morphogenesis	P	The process in which the anatomical structures of male genitalia are generated and organized from the genital imaginal disc.
48804	imaginal disc-derived female genitalia morphogenesis	P	The process in which the anatomical structures of female genitalia are generated and organized from the genital disc.
48805	imaginal disc-derived genitalia morphogenesis	P	The process in which the anatomical structures of genitalia are generated and organized from the genital imaginal disc.
48806	genitalia development	P	The process whose specific outcome is the progression of the genitalia over time, from its formation to the mature structure.
48807	female genitalia morphogenesis	P	The process in which the anatomical structures of female genitalia are generated and organized.
48808	male genitalia morphogenesis	P	The process in which the anatomical structures of male genitalia are generated and organized.
48809	analia morphogenesis	P	The process in which the anatomical structures of analia are generated and organized. The analia is the posterior-most vertral appendage that develops from the genital disc. An example of this process is analia morphogenesis in Drosophila melanogaster.
48810	female analia morphogenesis	P	The process in which the anatomical structures of the analia of the female are generated and organized. The analia is the posterior-most vertral appendage that develops from the genital disc. An example of this process is found in Drosophila melanogaster.
48811	male analia morphogenesis	P	The process in which the anatomical structures of the analia of the male are generated and organized. The analia is the posterior-most vertral appendage that develops from the genital disc.
48812	neuron projection morphogenesis	P	The process in which the anatomical structures of a neuron projection are generated and organized. A neuron projection is any process extending from a neural cell, such as axons or dendrites.
48813	dendrite morphogenesis	P	The process in which the anatomical structures of a dendrite are generated and organized. A dendrite is a freely branching protoplasmic process of a nerve cell.
48814	regulation of dendrite morphogenesis	P	Any process that modulates the frequency, rate or extent of dendrite morphogenesis.
48815	hermaphrodite genitalia morphogenesis	P	The process in which the anatomical structures of hermaphrodite genitalia are generated and organized.
48816	ocellus morphogenesis	P	The process in which the anatomical structures of the ocellus are generated and organized. The ocellus is a simple visual organ of insects.
48817	negative regulation of hair follicle maturation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of hair follicle maturation.
48818	positive regulation of hair follicle maturation	P	Any process that activates or increases the frequency, rate or extent of hair follicle maturation.
48819	regulation of hair follicle maturation	P	Any process that modulates the frequency, rate or extent of hair follicle maturation.
48820	hair follicle maturation	P	A developmental process, independent of morphogenetic (shape) change, that is required for a hair follicle to attain its fully functional state.
48821	erythrocyte development	P	The process whose specific outcome is the progression of an erythrocyte over time, from its formation to the mature structure.
48822	enucleate erythrocyte development	P	The process aimed at the progression of an enucleate erythrocyte over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.
48823	nucleate erythrocyte development	P	The process aimed at the progression of a nucleate erythrocyte over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.
48824	pigment cell precursor differentiation	P	The process in which a relatively unspecialized cell acquires specialized features of a pigment cell precursor.
48825	cotyledon development	P	The process whose specific outcome is the progression of the cotyledon over time, from its formation to the mature structure. The cotyledon is the modified leaf (seed leaf), found as part of the embryo in plant seeds. It is involved in either storage or absorption of food reserves. Dicotyledonous seeds contain two cotyledons, while monocotyledonous seeds contain only one. The cotyledons may appear above ground and show photosynthetic activity in the seedling.
48826	cotyledon morphogenesis	P	The process in which the anatomical structures of the cotyledon are generated and organized. The cotyledon is the modified leaf (seed leaf), found as part of the embryo in plant seeds. It is involved in either storage or absorption of food reserves. Dicotyledonous seeds contain two cotyledons, while monocotyledonous seeds contain only one. The cotyledons may appear above ground and show photosynthetic activity in the seedling.
48827	phyllome development	P	The process whose specific outcome is the progression of a phyllome over time, from its formation to the mature structure. A phyllome is a collective term for all the different types of leaves appearing on plants.
48829	root cap development	P	The process whose specific outcome is the progression of the root cap over time, from its formation to the mature structure. The root cap protects the root meristem from friction as the root grows through the soil. The cap is made up of a group of parenchyma cells which secrete a glycoprotein mucilage as a lubricant.
48830	adventitious root development	P	The process whose specific outcome is the progression of adventitious root over time, from its formation to the mature structure. Adventitious roots are post-embryonic roots that develop from the plant shoot.
48831	regulation of shoot system development	P	Any process that modulates the frequency, rate or extent of shoot development.
48832	specification of plant organ number	P	The regionalization process that modulates the quantity of a particular type of plant organ.
48833	specification of floral organ number	P	Any process that modulates the number of floral organs formed in a floral whorl.
48834	specification of petal number	P	Any process that modulates the number of petals formed in a flower.
48835	specification of decreased petal number	P	Any process that reduces the number of petals produced in a developing flower.
48836	specification of increased petal number	P	Any process that increases the number of petals produced in a developing flower.
48837	sorocarp sorus development	P	The process whose specific outcome is the progression of the sorocarp sorus over time, from its formation to the mature structure. A sorocarp sorus is the spore containing structure of a sorocarp.
48838	release of seed from dormancy	P	The process in which the dormant state is broken in a seed. Dormancy is characterized by a suspension of physiological activity that can be reactivated upon release.
48839	inner ear development	P	The process whose specific outcome is the progression of the inner ear over time, from its formation to the mature structure.
48840	otolith development	P	The process whose specific outcome is the progression of the otolith over time, from its formation to the mature structure.
48841	regulation of axon extension involved in axon guidance	P	Any process that modulates the frequency, rate or extent of axon extension involved in axon guidance.
48842	positive regulation of axon extension involved in axon guidance	P	Any process that activates, maintains or increases the frequency, rate or extent of axon extension involved in axon guidance.
48843	negative regulation of axon extension involved in axon guidance	P	Any process that stops, prevents, or reduces the frequency, rate or extent of axon extension involved in axon guidance.
48844	artery morphogenesis	P	The process in which the anatomical structures of arterial blood vessels are generated and organized. Arteries are blood vessels that transport blood from the heart to the body and its organs.
48845	venous blood vessel morphogenesis	P	The process in which the anatomical structures of venous blood vessels are generated and organized. Veins are blood vessels that transport blood from the body and its organs to the heart.
48846	axon extension involved in axon guidance	P	The long distance growth of a single cell process, that is involved in the migration of an axon growth cone, where the migration is directed to a specific target site by a combination of attractive and repulsive cues.
48847	adenohypophysis formation	P	The process that gives rise to adenohypophysis. This process pertains to the initial formation of a structure from unspecified parts. The adenohypophysis is the anterior part of the pituitary. It secretes a variety of hormones and its function is regulated by the hypothalamus.
48848	neurohypophysis morphogenesis	P	The process in which the anatomical structures of the neurohypophysis are generated and organized. The neurohypophysis is the part of the pituitary gland that secretes hormones involved in blood pressure regulation.
48849	neurohypophysis formation	P	The process that gives rise to neurohypophysis. This process pertains to the initial formation of a structure from unspecified parts. The neurohypophysis is the part of the pituitary gland that secretes hormones involved in blood pressure regulation.
48850	hypophysis morphogenesis	P	The process in which the anatomical structures of the hypophysis are generated and organized. The pituitary gland is an endocrine gland that secretes hormones that regulate many other glands.
48851	hypophysis formation	P	The process in which the anatomical structures of the hypophysis are generated and organized. The hypophysis is an endocrine gland that secretes hormones that regulate many other glands.
48852	diencephalon morphogenesis	P	The process in which the anatomical structures of the diencephalon are generated and organized. The diencephalon is the paired caudal parts of the prosencephalon from which the thalamus, hypothalamus, epithalamus and subthalamus are derived; these regions regulate autonomic, visceral and endocrine function, and process information directed to the cerebral cortex.
48853	forebrain morphogenesis	P	The process in which the anatomical structures of the forebrain are generated and organized. The forebrain is the anterior of the three primary divisions of the developing chordate brain or the corresponding part of the adult brain (in vertebrates, includes especially the cerebral hemispheres, the thalamus, and the hypothalamus and especially in higher vertebrates is the main control center for sensory and associative information processing, visceral functions, and voluntary motor functions).
48854	brain morphogenesis	P	The process in which the anatomical structures of the brain are generated and organized. The brain is one of the two components of the central nervous system and is the center of thought and emotion. It is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.).
48855	adenohypophysis morphogenesis	P	The process in which the anatomical structures of the adenohypophysis are generated and organized. The adenohypophysis is the anterior part of the pituitary. It secretes a variety of hormones and its function is regulated by the hypothalamus.
48856	anatomical structure development	P	The biological process whose specific outcome is the progression of an anatomical structure from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome.
48857	neural nucleus development	P	The biological process whose specific outcome is the progression of a neural nucleus from its initial condition to its mature state. A neural nucleus is an anatomical structure consisting of a discrete aggregate of neuronal soma.
48858	cell projection morphogenesis	P	The process in which the anatomical structures of a cell projection are generated and organized.
48859	formation of anatomical boundary	P	The process in which the limits of an anatomical structure are generated. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome.
48860	glioblast division	P	The process resulting in the physical partitioning and separation of a glioblast into daughter cells.
48861	leukemia inhibitory factor signaling pathway	P	Any series of molecular signals initiated by the binding of leukemia inhibitory factor to a receptor on the surface of the target cell, and ending with regulation of a downstream cellular process, e.g. transcription.
48863	stem cell differentiation	P	The process in which a relatively unspecialized cell acquires specialized features of a stem cell. A stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells.
48864	stem cell development	P	The process whose specific outcome is the progression of the stem cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to its specific fate.
48865	stem cell fate commitment	P	The process in which the developmental fate of a cell becomes restricted such that it will develop into a stem cell.
48866	stem cell fate specification	P	The process in which a cell becomes capable of differentiating autonomously into a stem cell in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed.
48867	stem cell fate determination	P	The process in which a cell becomes capable of differentiating autonomously into a stem cell regardless of its environment; upon determination, the cell fate cannot be reversed.
48868	pollen tube development	P	The process whose specific outcome is the progression of a pollen tube over time, from its initial formation to a mature structure.
48869	cellular developmental process	P	A biological process whose specific outcome is the progression of a cell over time from an initial condition to a later condition.
48870	cell motility	P	Any process involved in the controlled self-propelled movement of a cell that results in translocation of the cell from one place to another.
48871	multicellular organismal homeostasis	P	Any process involved in the maintenance of an internal steady state at the level of the multicellular organism.
48872	homeostasis of number of cells	P	Any biological process involved in the maintenance of the steady-state number of cells within a population of cells.
48873	homeostasis of number of cells within a tissue	P	Any biological process involved in the maintenance of the steady-state number of cells within a population of cells in a tissue.
48874	homeostasis of number of cells in a free-living population	P	The biological process involved in maintaining the steady-state number of cells within a population of free-living cells such as the bacteria in the gut.
48875	chemical homeostasis within a tissue	P	Any process involved in the maintenance of the internal steady state of the amount of a chemical at the level of the tissue.
48876	chemical homeostasis within retina	P	Any process involved in the maintenance of the internal steady state of the amount of a chemical at the level of the retina.
48877	homeostasis of number of retina cells	P	Any biological process involved in the maintenance of the steady-state number of cells within a population of cells in the retina.
48878	chemical homeostasis	P	Any biological process involved in the maintenance of an internal steady state of a chemical.
48880	sensory system development	P	The process whose specific outcome is the progression of a sensory system over time from its formation to the mature structure.
48881	mechanosensory lateral line system development	P	The process whose specific outcome is the progression of the mechanosensory lateral line system over time, from its formation to the mature structure. The mechanosensory lateral line system consists of small sensory patches (neuromasts) located superficially on the skin or just under the skin in fluid-filled canals on the head and body of all fishes and most amphibians. The neuromasts are innervated by several lateral line nerves, which project primarily to the hindbrain. The mechanosensory lateral line system is stimulated by local water displacements and vibrations, and detects propulsion of the fish through the water, as well as facilitating shoaling, prey capture, and predator and obstacle avoidance.
48882	lateral line development	P	The process whose specific outcome is the progression of the lateral line over time, from its formation to the mature structure. The lateral line consists of small sensory patches (neuromasts) located superficially on the skin or just under the skin in fluid-filled canals on the head and body of all fishes and most amphibians. The lateral line develops from cranial ectodermal placodes situated behind the ear and between the eye and ear.
48883	neuromast primordium migration	P	The migration of a cluster of a relatively undifferentiated cell originating at specific cephalic placodes and depositing proneuromasts along a developing lateral line, from which the neuromasts will develop.
48884	neuromast development	P	The process whose specific outcome is the progression of the neuromast over time, from its formation to the mature structure. The neuromast is the sensory organ of the lateral line and is composed of a population of sensory hair cells, and nonsensory supporting cells and mantle cells. Neuromasts are located superficially on the epithelium or in lateral line canals.
48885	neuromast deposition	P	The process in which a migrating neuromast primordium deposits clusters of undifferentiated cells (proneuromasts) along its migratory path in a developing lateral line.
48886	neuromast hair cell differentiation	P	The process in which a relatively unspecialized cell acquires specialized features of a neuromast hair cell. Hair cells are the sensory receptors of the neuromast and are located in a portion of the neuromast called the sensory strip. Each hair cell of the neuromast is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. There are approximately seven hair cells within each neuromast, with each hair cell innervated by afferent and efferent neurons.
48887	cupula development	P	The process whose specific outcome is the progression of the cupula over time, from its formation to the mature structure. The cupula is secreted by mantle cells and the ciliary bundles of all of the hair cells of the neuromast are embedded in it. The cupula provides a mechanical linkage between the hair cells and the external hydrodynamic environment. The cupula of superficial neuromasts grows continuously, while the height of the cupula of canal neuromasts is limited by canal diameter.
48888	neuromast mantle cell differentiation	P	The process in which a relatively unspecialized cell acquires specialized features of a neuromast mantle cell. Mantle cells are non-sensory cells that surround the sensory strip, separating the neuromast from the epidermis. Mantle cells secrete the cupula in which the ciliary bundles of all of the hair cells are embedded.
48889	neuromast support cell differentiation	P	The process in which a relatively unspecialized cell acquires specialized features of a neuromast support cell. Support cells are non-sensory cells of the neuromast that extend between the sensory hair cells from the basement membrane to the apical surface; they are surrounded by mantle cells.
48890	lateral line ganglion development	P	The process whose specific outcome is the progression of the lateral line ganglion over time, from its formation to the mature structure. The lateral line ganglion develops from cranial ectodermal placodes situated between the eye and ear and behind the ear.
48891	lateral line ganglion neuron differentiation	P	The process in which a relatively unspecialized cell acquires specialized features of a lateral line ganglion neuron.
48892	lateral line nerve development	P	The process whose specific outcome is the progression of the lateral line nerve over time, form its formation to the mature structure. Lateral line nerves project primarily to an octavolateralis column in the hindbrain that consists of the medial octavolateralis nucleus (MON), the caudal octavolateralis nucleus, and the magnocellular nucleus.
48893	afferent axon development in lateral line nerve	P	The process whose specific outcome is the progression of an afferent axon in a lateral line nerve over time from its formation to the mature structure. This process includes axonogenesis and pathfinding of the afferent axons in any lateral line nerve.
48894	efferent axon development in a lateral line nerve	P	The process whose specific outcome is the progression of an efferent axon in a lateral line nerve over time from its formation to the mature structure. This process includes axonogenesis and pathfinding of the efferent axons in any lateral line nerve.
48895	lateral line nerve glial cell differentiation	P	The process in which a relatively unspecialized cell acquires specialized features of a glial cell in a lateral line nerve.
48896	lateral line nerve glial cell migration	P	The movement of a glial cell along the axons in a lateral line nerve.
48897	myelination of lateral line nerve axons	P	The formation of compact myelin sheaths around the axons of a lateral line nerve.
48898	anterior lateral line system development	P	The process whose specific outcome is the progression of the anterior lateral line system over time, from its formation to the mature structure. The anterior lateral line system develops from cranial ectodermal placodes, situated between the eye and the ear, that give rise to both the neuromasts and the anterior lateral line sensory nerves that innervate the neuromasts. The anterior lateral line system consists of small sensory patches (neuromasts) located superficially on the skin or just under the skin in fluid-filled canals on the head of all fishes and most amphibians and are innervated by several lateral line nerves, which project to the hindbrain. The anterior lateral line system is stimulated by local water displacements and vibrations, and detects propulsion of the fish through the water, as well as facilitating shoaling, prey capture, and predator and obstacle avoidance.
48899	anterior lateral line development	P	The process whose specific outcome is the progression of the anterior lateral line over time, from its formation to the mature structure. The anterior lateral line consists of small sensory patches (neuromasts) located superficially on the skin or just under the skin in fluid-filled canals on the head of all fishes and most amphibians. The anterior lateral line develops from cranial ectodermal placodes situated between the eye and ear.
48900	anterior lateral line neuromast primordium migration	P	The migration of a cluster of a relatively undifferentiated cell along the developing anterior lateral line, originating from cranial ectodermal placodes situated between the eye and the ear. The neuromast primordium deposits proneuromasts along the lateral line, from which the neuromasts will develop.
48901	anterior lateral line neuromast development	P	The process whose specific outcome is the progression of the anterior lateral line neuromast over time, from its formation to the mature structure. The neuromast is the sensory receptor of the anterior lateral line system and is composed of a population of sensory hair cells, and nonsensory supporting cells and mantle cells. Neuromast are located superficially on the epithelium or in lateral line canals.
48902	anterior lateral line neuromast deposition	P	The process in which a migrating neuromast primordium deposits clusters of undifferentiated cells (proneuromasts) along its migratory path in the developing anterior lateral line.
48903	anterior lateral line neuromast hair cell differentiation	P	The process in which a relatively unspecialized cell acquires specialized features of an anterior lateral line neuromast hair cell. Neuromast hair cells are the sensory receptors of the neuromast and are located in a portion of the neuromast called the sensory strip. Each hair cell of the neuromast is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. There are approximately seven hair cells within each neuromast, with each hair cell innervated by afferent and efferent neurons.
48904	anterior lateral line neuromast cupula development	P	The process whose specific outcome is the progression of the anterior lateral line neuromast cupula over time, from its formation to the mature structure. The cupula is secreted by mantle cells and the ciliary bundles of all of the hair cells of the neuromast are embedded in it. The cupula provides a mechanical linkage between the hair cells and the external hydrodynamic environment. The cupula of superficial neuromasts grows continuously, while the height of the cupula of canal neuromasts is limited by canal diameter.
48905	anterior lateral line neuromast mantle cell differentiation	P	The process in which a relatively unspecialized cell acquires specialized features of an anterior lateral line neuromast mantle cell. Mantle cells are non-sensory cells that surround the sensory strip, separating the neuromast from the epidermis. Mantle cells secrete the cupula in which the ciliary bundles of all of the hair cells are embedded.
48906	anterior lateral line neuromast support cell differentiation	P	The process in which a relatively unspecialized cell acquires specialized features of an anterior lateral line neuromast support cell. Support cells are non-sensory cells of the neuromast that extend between the sensory hair cells from the basement membrane to the apical surface; they are surrounded by mantle cells.
48907	anterior lateral line ganglion development	P	The process whose specific outcome is the progression of the anterior lateral line ganglion over time, from its formation to the mature structure. The anterior lateral line ganglion develops from cranial ectodermal placodes situated between the eye and ear.
48908	anterior lateral line ganglion neuron differentiation	P	The process in which a relatively unspecialized cell acquires specialized features of a neuron of the anterior lateral line ganglion.
48909	anterior lateral line nerve development	P	The process whose specific outcome is the progression of the anterior lateral line nerve over time, form its formation to the mature structure. The anterior lateral line nerve contains efferent axons that innervate hair cells of the ALL and afferent axons that project to an octavolateralis column in the hindbrain. The octavolateralis column consists of the medial octavolateralis nucleus (MON), the caudal octavolateralis nucleus, and the magnocellular nucleus.
48910	afferent axon development in anterior lateral line nerve	P	The process whose specific outcome is the progression of an afferent axon in the anterior lateral line nerve over time from its formation to the mature structure. This process includes axonogenesis and pathfinding of the afferent axons in the anterior lateral line nerve.
48911	efferent axon development in anterior lateral line nerve	P	The process whose specific outcome is the progression of an efferent axon in the anterior lateral line nerve over time from its formation to the mature structure. This process includes axonogenesis and pathfinding of the efferent axons in the anterior lateral line nerve.
48912	glial cell migration in anterior lateral line nerve	P	The movement of a glial cell along the axons in the anterior lateral line nerve.
48913	anterior lateral line nerve glial cell differentiation	P	The process in which a relatively unspecialized cell acquires specialized features of a glial cell in the anterior lateral line nerve.
48914	myelination of anterior lateral line nerve axons	P	The formation of compact myelin sheaths around the axons of the anterior lateral line nerve.
48915	posterior lateral line system development	P	The process whose specific outcome is the progression of the posterior lateral line system over time, from its formation to the mature structure. The posterior lateral line system develops from cranial ectodermal placodes, situated behind the ear, that give rise to both the neuromasts and the posterior lateral line sensory nerves that innervate the neuromasts. The posterior lateral line system consists of small sensory patches (neuromasts) located superficially on the skin or just under the skin in fluid-filled canals on the head of all fishes and most amphibians. The neuromasts are innervated by several lateral line nerves, which project primarily to the hindbrain. The posterior mechanosensory lateral line system is stimulated by local water displacements and vibrations, and detects propulsion of the fish through the water, as well as facilitating shoaling, prey capture, and predator and obstacle avoidance.
48916	posterior lateral line development	P	The process whose specific outcome is the progression of the posterior lateral line over time, from its formation to the mature structure. The posterior lateral line consists of small sensory patches (neuromasts) located superficially on the skin or just under the skin in fluid-filled canals on the body and trunk of all fishes and most amphibians. The posterior lateral line develops from cranial ectodermal placodes situated behind the ear.
48917	posterior lateral line ganglion development	P	The process whose specific outcome is the progression of the posterior lateral line ganglion over time, from its formation to the mature structure. The posterior lateral line ganglion develops from cranial ectodermal placodes situated behind the ear.
48918	posterior lateral line nerve development	P	The process whose specific outcome is the progression of the posterior lateral line nerve over time, from its formation to the mature structure. The posterior lateral line nerve innervates hair cells of the PLL and projects to an octavolateralis column in the hindbrain that consists of the medial octavolateralis nucleus (MON), the caudal octavolateralis nucleus, and the magnocellular nucleus.
48919	posterior lateral line neuromast development	P	The process whose specific outcome is the progression of the posterior lateral line neuromast over time, from its formation to the mature structure. The neuromast is the sensory receptor of the anterior lateral line system and is composed of a population of sensory hair cells, and nonsensory supporting cells and mantle cells. Neuromast are located superficially on the epithelium or in lateral line canals.
48920	posterior lateral line neuromast primordium migration	P	The migration of a relatively undifferentiated cell along the developing posterior lateral line, originating from cranial ectodermal placodes situated behind the ear. The neuromast primordium deposits proneuromasts along the lateral line, from which the neuromasts will develop.
48921	posterior lateral line neuromast cupula development	P	The process whose specific outcome is the progression of the posterior lateral line neuromast cupula over time, from its formation to the mature structure. The cupula is secreted by mantle cells and the ciliary bundles of all of the hair cells of the neuromast are embedded in it. The cupula provides a mechanical linkage between the hair cells and the external hydrodynamic environment. The cupula of superficial neuromasts grows continuously, while the height of the cupula of canal neuromasts is limited by canal diameter.
48922	posterior lateral line neuromast deposition	P	The process in which a migrating neuromast primordium deposits clusters of undifferentiated cells (proneuromasts) along its migratory path in the developing posterior lateral line.
48923	posterior lateral line neuromast hair cell differentiation	P	The process in which a relatively unspecialized cell acquires specialized features of a posterior lateral line neuromast hair cell. (N.B. This may be development of neuromast hair cell type or a set of cell of neuromast hair cell type. This will involve the change of a cell or set of cells from one cell identity to another). Hair cells are the sensory receptors of the neuromast and are located in a portion of the neuromast called the sensory strip. Each hair cell of the neuromast is morphologically polarized as a result of the relative position of the single kinocilium and the clusters of stereocilia on its apical surface. There are approximately seven hair cells within each neuromast, with each hair cell innervated by afferent and efferent neurons.
48924	posterior lateral line neuromast mantle cell differentiation	P	The process in which a relatively unspecialized cell acquires specialized features of a posterior lateral line neuromast mantle cell. (N.B. This may be development of neuromast mantle cell type or a set of cells of neuromast mantle cell type. This will involve the change of a cell or set of cells from one cell identity to another). Mantle cells are non-sensory cells that surround the sensory strip, separating the neuromast from the epidermis. Mantle cells secrete the cupula in which the ciliary bundles of all of the hair cells are embedded.
48925	lateral line system development	P	The process whose specific outcome is the progression of the lateral line system over time, from its formation to the mature structure. The lateral line system is a network of sensory organs (neuromasts) and lateral line nerves located superficially on the skin or just under the skin in fluid-filled canals on the head and body of all fishes and most amphibians. The lateral line system develops from cranial ectodermal placodes situated between the eye and ear.
48926	electrosensory lateral line system development	P	The process whose specific outcome is the progression of the electrosensory lateral line system over time, from its formation to the mature structure.
48927	posterior lateral line neuromast support cell differentiation	P	The process in which a relatively unspecialized cell acquires specialized features of a posterior lateral line neuromast support cell. Support cells are non-sensory cells of the neuromast that extend between the sensory hair cells from the basement membrane to the apical surface; they are surrounded by mantle cells.
48928	posterior lateral line ganglion neuron differentiation	P	The process in which a relatively unspecialized cell acquires specialized features of a neuron of the posterior lateral line ganglion.
48929	efferent axon development in posterior lateral line nerve	P	The process whose specific outcome is the progression of an efferent axon in the posterior lateral line nerve over time from its formation to the mature structure. This process includes axonogenesis and pathfinding of the efferent axons in the posterior lateral line nerve.
48930	glial cell migration in posterior lateral line nerve	P	The movement of a glial cell along the axons in the posterior lateral line nerve.
48931	posterior lateral line nerve glial cell differentiation	P	The process in which a relatively unspecialized cell acquires specialized features of a glial cell in the posterior lateral line nerve.
48932	myelination of posterior lateral line nerve axons	P	The formation of compact myelin sheaths around the axons of the posterior lateral line nerve.
48933	afferent axon development in posterior lateral line nerve	P	The process whose specific outcome is the progression of an afferent axon in the posterior lateral line nerve over time from its formation to the mature structure. This process includes axonogenesis and pathfinding of the afferent axons in the posterior lateral line nerve.
48934	peripheral nervous system neuron differentiation	P	The process in which a relatively unspecialized cell acquires specialized features of a neuron whose cell body resides in the peripheral nervous system.
48935	peripheral nervous system neuron development	P	The process whose specific outcome is the progression of a neuron whose cell body is located in the peripheral nervous system, from initial commitment of the cell to a neuronal fate, to the fully functional differentiated neuron.
48936	peripheral nervous system neuron axonogenesis	P	Generation of a long process from a neuron whose cell body resides in the peripheral nervous system. The axon carries action potential from the cell body towards target cells.
48937	lateral line nerve glial cell development	P	The process aimed at the progression of a lateral line glial cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.
48938	lateral line nerve glial cell morphogenesis involved in differentiation	P	The process in which the structure of a glial cell in a lateral line nerve is generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a glial cell in a lateral line nerve.
48939	anterior lateral line nerve glial cell development	P	The process aimed at the progression of a glial cell in the anterior lateral line nerve over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.
48940	anterior lateral line nerve glial cell morphogenesis involved in differentiation	P	The process in which the structures of a glial cell in the anterior lateral line nerve are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a glial cell in the anterior lateral line nerve.
48941	posterior lateral line nerve glial cell development	P	The process aimed at the progression of a glial cell in the posterior lateral line nerve over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.
48942	posterior lateral line nerve glial cell morphogenesis involved in differentiation	P	The process in which the structures of a glial cell in the posterior lateral line nerve are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a glial cell in the posterior lateral line nerve.
50000	chromosome localization	P	Any process in which a chromosome is transported to, or maintained in, a specific location.
50001	D-glutaminase activity	F	Catalysis of the reaction: H2O + L-glutamine = NH3 + D-glutamate.
50002	D-proline reductase (dithiol) activity	F	Catalysis of the reaction: lipoate + 5-aminopentanoate = dihydrolipoate + D-proline.
50003	deoxycytidylate C-methyltransferase activity	F	Catalysis of the reaction: 5,10-methylenetetrahydrofolate + dCMP = 2'-deoxy-5-methyl-5'-cytidylate + 7,8-dihydrofolate.
50004	isoflavone 7-O-glucosyltransferase activity	F	Catalysis of the reaction: UDP-glucose + isoflavone = UDP + isoflavone 7-O-beta-D-glucoside.
50005	isohexenylglutaconyl-CoA hydratase activity	F	Catalysis of the reaction: 3-hydroxy-3-(4-methylpent-3-en-1-yl)glutaryl-CoA = 3-(4-methylpent-3-en-1-yl)pent-2-enedioyl-CoA + H(2)O.
50006	isomaltulose synthase activity	F	Catalysis of the reaction: sucrose = 6-O-alpha-D-glucopyranosyl-D-fructofuranose.
50007	isonocardicin synthase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine(1+) + nocardicin E = S-methyl-5'-thioadenosine + H(+) + isonocardicin A.
50008	isopiperitenone delta-isomerase activity	F	Catalysis of the reaction: isopiperitenone = piperitenone.
50009	isopropanol dehydrogenase (NADP+) activity	F	Catalysis of the reaction: NADP(+) + propan-2-ol = acetone + H(+) + NADPH.
50010	isovitexin beta-glucosyltransferase activity	F	Catalysis of the reaction: isovitexin + UDP-D-glucose = H(+) + isovitexin 2''-O-beta-D-glucoside + UDP.
50011	itaconyl-CoA hydratase activity	F	Catalysis of the reaction: citramalyl-CoA = itaconyl-CoA + H2O.
50012	juglone 3-monooxygenase activity	F	Catalysis of the reaction: 5-hydroxy-1,4-naphthoquinone + AH(2) + O(2) = 3,5-dihydroxy-1,4-naphthoquinone + A + H(2)O + H(+).
50013	2-dehydropantoate aldolase activity	F	Catalysis of the reaction: 2-dehydropantoate = 3-methyl-2-oxobutanoate + formaldehyde.
50014	ketotetrose-phosphate aldolase activity	F	Catalysis of the reaction: L-erythrulose 1-phosphate = formaldehyde + glycerone phosphate.
50015	kievitone hydratase activity	F	Catalysis of the reaction: kievitone hydrate = H(2)O + H(+) + kievitone.
50016	kynurenine 7,8-hydroxylase activity	F	Catalysis of the reaction: kynurenate + donor-H2 + O2 = 7,8-dihydro-7,8-dihydroxykynurenate + acceptor.
50017	L-3-cyanoalanine synthase activity	F	Catalysis of the reaction: L-cysteine + HCN = sulfide + L-3-cyanoalanine.
50018	L-amino-acid dehydrogenase activity	F	Catalysis of the reaction: an L-amino acid + H2O + NAD+ = a 2-oxo acid + NH3 + NADH.
50019	L-arabinitol 4-dehydrogenase activity	F	Catalysis of the reaction: L-arabinitol + NAD(+) = L-xylulose + H(+) + NADH.
50020	L-arabinonate dehydratase activity	F	Catalysis of the reaction: L-arabinonate = 2-dehydro-3-deoxy-L-arabinonate + H(2)O.
50021	L-arabinonolactonase activity	F	Catalysis of the reaction: L-arabinono-1,4-lactone + H(2)O = L-arabinonate + H(+).
50022	L-arabinose 1-dehydrogenase (NAD+) activity	F	Catalysis of the reaction: L-arabinose + NAD+ = L-arabinono-1,4-lactone + NADH.
50023	L-fuconate dehydratase activity	F	Catalysis of the reaction: L-fuconate = 2-dehydro-3-deoxy-L-fuconate + H(2)O.
50024	L-galactonolactone oxidase activity	F	Catalysis of the reaction: L-galactono-1,4-lactone + O(2) = L-ascorbate + H(2)O(2) + H(+).
50025	L-glutamate oxidase activity	F	Catalysis of the reaction: L-glutamate + O2 + H2O = 2-oxoglutarate + NH3 + H2O2.
50026	L-glycol dehydrogenase activity	F	Catalysis of the reaction: an L-glycol + NAD(P)+ = a 2-hydroxycarbonyl compound + NAD(P)H + H+.
50028	L-lysine-lactamase activity	F	Catalysis of the reaction: L-2-aminohexano-6-lactam + H(2)O = L-lysine.
50029	L-lysine oxidase activity	F	Catalysis of the reaction: L-lysine + H(2)O + O(2) = 6-amino-2-oxohexanoate + H(2)O(2) + NH(4)(+).
50030	L-pipecolate dehydrogenase activity	F	Catalysis of the reaction: L-pipecolate + acceptor = delta1-piperideine-6-carboxylate + reduced acceptor. Delta1-piperideine-6-carboxylate is also known as 2,3,4,5-tetrahydropyridine-2-carboxylate.
50031	L-pipecolate oxidase activity	F	Catalysis of the reaction: L-pipecolate + O(2) = 2,3,4,5-tetrahydropyridine-2-carboxylate + H(2)O(2) + H(+). Delta1-piperideine-6-carboxylate is also known as 2,3,4,5-tetrahydropyridine-2-carboxylate.
50032	L-rhamnonate dehydratase activity	F	Catalysis of the reaction: L-rhamnonate = 2-dehydro-3-deoxy-L-rhamnonate + H(2)O.
50033	L-rhamnono-1,4-lactonase activity	F	Catalysis of the reaction: L-rhamnono-1,4-lactone + H(2)O = L-rhamnonate + H(+).
50034	L-rhamnose 1-dehydrogenase activity	F	Catalysis of the reaction: L-rhamnofuranose + NAD(+) = L-rhamnono-1,4-lactone + H(+) + NADH.
50035	L-sorbose oxidase activity	F	Catalysis of the reaction: L-sorbose + O(2) = 5-dehydro-D-fructose + H(2)O(2).
50036	L-threonate 3-dehydrogenase activity	F	Catalysis of the reaction: L-threonate + NAD(+) = 3-dehydro-L-threonate + H(+) + NADH.
50037	L-xylose 1-dehydrogenase activity	F	Catalysis of the reaction: aldehydo-L-xylose + NADP(+) = L-xylono-1,4-lactone + H(+) + NADPH.
50038	L-xylulose reductase (NADP+) activity	F	Catalysis of the reaction: NADP(+) + xylitol = L-xylulose + H(+) + NADPH.
50039	lactaldehyde reductase (NADPH) activity	F	Catalysis of the reaction: NADP(+) + propane-1,2-diol = (S)-lactaldehyde + H(+) + NADPH.
50040	lactate 2-monooxygenase activity	F	Catalysis of the reaction: (S)-lactate + O(2) = acetate + CO(2) + H(2)O.
50041	lactate aldolase activity	F	Catalysis of the reaction: (S)-lactate = acetaldehyde + formate.
50042	lactate-malate transhydrogenase activity	F	Catalysis of the reaction: (S)-lactate + oxaloacetate = malate + pyruvate.
50043	lactate racemase activity	F	Catalysis of the reaction: (S)-lactate = (R)-lactate.
50044	galactose-6-phosphate isomerase activity	F	Catalysis of the reaction: D-galactose 6-phosphate = D-tagatose 6-phosphate.
50045	laminaribiose phosphorylase activity	F	Catalysis of the reaction: 3-beta-D-glucosyl-D-glucose + phosphate = D-glucose + alpha-D-glucose 1-phosphate.
50046	lathosterol oxidase activity	F	Catalysis of the reaction: 5-alpha-cholest-7-en-3-beta-ol + O2 = cholesta-5,7-dien-3-beta-ol + H2O2.
50047	leucine 2,3-aminomutase activity	F	Catalysis of the reaction: L-leucine = (3R)-beta-leucine.
50048	L-leucine:2-oxoglutarate aminotransferase activity	F	Catalysis of the reaction: L-leucine + 2-oxoglutarate = 4-methyl-2-oxopentanoate + L-glutamate.
50049	leucine dehydrogenase activity	F	Catalysis of the reaction: L-leucine + H2O + NAD+ = 4-methyl-2-oxopentanoate + NH3 + NADH.
50050	leucine N-acetyltransferase activity	F	Catalysis of the reaction: L-leucine + acetyl-CoA = N-acetyl-L-leucine + CoA + H(+).
50051	leukotriene-B4 20-monooxygenase activity	F	Catalysis of the reaction: (6Z,8E,10E,14Z)-(5S,12R)-5,12-dihydroxyicosa-6,8,10,14-tetraenoate + NADPH + H+ + O2 = (6Z,8E,10E,14Z)-(5S,12R)-5,12,20-trihydroxyicosa-6,8,10,14-tetraenoate + NADP+ + H2O.
50052	leukotriene-E4 20-monooxygenase activity	F	Catalysis of the reaction: H(+) + leukotriene E(4) + NADPH + O(2) = 20-hydroxy-leukotriene E(4) + H(2)O + NADP(+).
50053	levansucrase activity	F	Catalysis of the reaction: sucrose + 2,6-beta-D-fructosyl(n) = glucose + 2,6-beta-D-fructosyl(n+1).
50054	lignostilbene alpha beta-dioxygenase activity	F	Catalysis of the reaction: 1,2-bis(4-hydroxy-3-methoxyphenyl)ethylene + O(2) = 2 vanillin.
50055	limonin-D-ring-lactonase activity	F	Catalysis of the reaction: limonoate D-ring-lactone + H2O = limonoate.
50056	linalool 8-monooxygenase activity	F	Catalysis of the reaction: AH(2) + linalool + O(2) = (2E)-2,6-dimethylocta-2,7-diene-1,6-diol + A + H(2)O.
50057	linamarin synthase activity	F	Catalysis of the reaction: UDP-glucose + 2-hydroxy-2-methylpropanenitrile = UDP + linamarin.
50058	linoleate isomerase activity	F	Catalysis of the reaction: linoleate = 9-cis,11-trans-octadecadienoate.
50059	lombricine kinase activity	F	Catalysis of the reaction: ATP + lombricine = ADP + N-phospholombricine.
50060	long-chain-alcohol dehydrogenase activity	F	Catalysis of the reaction: a long-chain alcohol + 2 NAD+ + H2O = a long-chain carboxylate + 2 NADH.
50061	long-chain-aldehyde dehydrogenase activity	F	Catalysis of the reaction: a long-chain aldehyde + NAD+ = a long-chain carboxylate + NADH + H+. A long-chain aldehyde is one with more than 12 carbons.
50062	long-chain-fatty-acyl-CoA reductase activity	F	Catalysis of the reaction: a long-chain aldehyde + CoA + NADP+ = a long-chain acyl-CoA + NADPH.
50063	low-density-lipoprotein particle receptor kinase activity	F	Catalysis of the reaction: ATP + low-density lipoprotein L-serine = ADP + low-density lipoprotein O-phospho-L-serine.
50064	luteolin 7-O-glucuronosyltransferase activity	F	Catalysis of the reaction: luteolin + UDP-alpha-D-glucuronate = luteolin 7-O-beta-D-glucosiduronate + UDP.
50065	lysine-pyruvate 6-transaminase activity	F	Catalysis of the reaction: L-lysine + pyruvate = L-alanine + L-allysine.
50066	lysine 2,3-aminomutase activity	F	Catalysis of the reaction: L-lysine = (3S)-3,6-diaminohexanoate.
50067	lysine 2-monooxygenase activity	F	Catalysis of the reaction: L-lysine + O(2) = 5-aminopentanamide + CO(2) + H(2)O.
50068	lysine carbamoyltransferase activity	F	Catalysis of the reaction: L-lysine + carbamoyl phosphate = L-homocitrulline + H(+) + phosphate.
50069	lysine dehydrogenase activity	F	Catalysis of the reaction: L-lysine + NAD+ = 1,2-didehydropiperidine-2-carboxylate + NH3 + NADH.
50070	lysolecithin acylmutase activity	F	Catalysis of the reaction: 1-acyl-sn-glycero-3-phosphocholine = 2-acyl-sn-glycero-3-phosphocholine.
50071	lysyltransferase activity	F	Catalysis of the reaction: L-lysyl-tRNA + phosphatidylglycerol = tRNA + 3-phosphatidyl-1'-(3'-O-L-lysyl)glycerol.
50072	m7G(5')pppN diphosphatase activity	F	Catalysis of the reaction: 7-methylguanosine 5'-triphospho-5'-polynucleotide + H2O = 7-methylguanosine 5'-phosphate + polynucleotide.
50073	macrolide 2'-kinase activity	F	Catalysis of the reaction: ATP + oleandomycin = ADP + 2 H(+) + oleandomycin 2'-O-phosphate.
50074	malate-CoA ligase activity	F	Catalysis of the reaction: ATP + malate + CoA = ADP + phosphate + malyl-CoA.
50075	maleate hydratase activity	F	Catalysis of the reaction: (R)-malate = H(2)O + maleate.
50076	maleate isomerase activity	F	Catalysis of the reaction: maleate = fumarate.
50077	maleylpyruvate isomerase activity	F	Catalysis of the reaction: 3-maleylpyruvate = 3-fumarylpyruvate.
50078	malonate CoA-transferase activity	F	Catalysis of the reaction: acetyl-CoA + malonate = acetate + malonyl-CoA.
50079	acetylenecarboxylate hydratase activity, producing 3-oxopropanoate	F	Catalysis of the reaction: 3-oxopropanoate = propynoate + H2O.
50080	malonyl-CoA decarboxylase activity	F	Catalysis of the reaction: malonyl-CoA = acetyl-CoA + CO2.
50081	maltose-6'-phosphate glucosidase activity	F	Catalysis of the reaction: H2O + maltose 6'-phosphate = D-glucose + D-glucose 6-phosphate.
50082	maltose phosphorylase activity	F	Catalysis of the reaction: maltose + phosphate = D-glucose + beta-D-glucose 1-phosphate.
50083	malyl-CoA lyase activity	F	Catalysis of the reaction: (3S)-3-carboxy-3-hydroxypropanoyl-CoA = acetyl-CoA + glyoxylate.
50084	mannitol-1-phosphatase activity	F	Catalysis of the reaction: D-mannitol 1-phosphate + H(2)O = D-mannitol + 2 H(+) + phosphate.
50085	mannitol 2-dehydrogenase (NADP+) activity	F	Catalysis of the reaction: D-mannitol + NADP(+) = D-fructose + H(+) + NADPH.
50086	mannitol 2-dehydrogenase activity	F	Catalysis of the reaction: D-mannitol + NAD+ = D-fructose + NADH.
50087	mannitol dehydrogenase (cytochrome) activity	F	Catalysis of the reaction: D-mannitol + ferricytochrome c = D-fructose + ferrocytochrome c.
50088	mannose-6-phosphate 6-reductase activity	F	Catalysis of the reaction: D-mannitol 1-phosphate + NADP(+) = D-mannose 6-phosphate + 3 H(+) + NADPH.
50089	mannose isomerase activity	F	Catalysis of the reaction: D-mannose = D-fructose.
50090	mannuronate reductase activity	F	Catalysis of the reaction: D-mannonate + NAD(P)+ = D-mannuronate + NAD(P)H + H+.
50091	melilotate 3-monooxygenase activity	F	Catalysis of the reaction: 3-(2-hydroxyphenyl)propanoate + H(+) + NADH + O(2) = 3-(2,3-dihydroxyphenyl)propanoate + H(2)O + NAD(+).
50092	meso-tartrate dehydrogenase activity	F	Catalysis of the reaction: (2R,3S)-tartrate + NAD(+) = dihydroxyfumarate + H(+) + NADH.
50093	methanol dehydrogenase activity	F	Catalysis of the reaction: methanol + NAD(+) = formaldehyde + H(+) + NADH.
50094	methionine-glyoxylate transaminase activity	F	Catalysis of the reaction: L-methionine + glyoxylate = 4-methylthio-2-oxobutanoate + glycine.
50095	methionine decarboxylase activity	F	Catalysis of the reaction: L-methionine + H(+) = 3-methylthiopropanamine + CO(2).
50096	methylaspartate ammonia-lyase activity	F	Catalysis of the reaction: threo-3-methyl-L-aspartate = mesaconate + NH(4)(+).
50097	methylaspartate mutase activity	F	Catalysis of the reaction: threo-3-methyl-L-aspartate = L-glutamate.
50098	methylguanidinase activity	F	Catalysis of the reaction: H(2)O + methylguanidine = methylammonium + urea.
50099	methylglutamate dehydrogenase activity	F	Catalysis of the reaction: N-methyl-L-glutamate + A + H(2)O = L-glutamate + AH(2) + formaldehyde.
50100	methylitaconate delta-isomerase activity	F	Catalysis of the reaction: 2-methylene-3-methylsuccinate = dimethylmaleate.
50101	mimosinase activity	F	Catalysis of the reaction: L-mimosine + H(2)O = 3-hydroxy-4H-pyrid-4-one + L-serine.
50102	cellodextrin phosphorylase activity	F	Catalysis of the reaction: 1,4-beta-D-glucosyl(n) + phosphate = 1,4-beta-D-glucosyl(n-1) + alpha-D-glucose 1-phosphate.
50103	dextrin dextranase activity	F	Catalysis of the reaction: 1,4-alpha-D-glucosyl(n) + 1,6-alpha-D-glucosyl(m) = 1,4-alpha-D-glucosyl(n-1) + 1,6-alpha-D-glucosyl(m+1).
50104	L-gulonate 3-dehydrogenase activity	F	Catalysis of the reaction: L-gulonate + NAD(+) = 3-dehydro-L-gulonate + H(+) + NADH.
50105	L-gulonolactone oxidase activity	F	Catalysis of the reaction: L-gulono-1,4-lactone + O2 = L-xylo-hex-3-ulonolactone + H2O2.
50106	monomethyl-sulfatase activity	F	Catalysis of the reaction: H(2)O + monomethyl sulfate = H(+) + methanol + sulfate.
50107	monoterpenol O-acetyltransferase activity	F	Catalysis of the reaction: acetyl-CoA + a monoterpenol = CoA + a monoterpenol acetate ester.
50108	monoterpenyl-diphosphatase activity	F	Catalysis of the reaction: monoterpenyl diphosphate + H2O = monoterpenol + diphosphate.
50109	morphine 6-dehydrogenase activity	F	Catalysis of the reaction: morphine + NAD(P)+ = morphinone + NAD(P)H + H+.
50110	mucinaminylserine mucinaminidase activity	F	Catalysis of the reaction: D-galactosyl-3-(N-acetyl-beta-D-galactosaminyl)-L-serine + H2O = D-galactosyl-3-N-acetyl-beta-D-galactosamine + L-serine.
50111	mycocerosate synthase activity	F	Catalysis of the reaction: acyl-CoA + 7n H(+) + n methylmalonyl-CoA + 2n NADPH = n CO(2) + n CoA + n H(2)O + multi-methyl-branched acyl-CoA + 2n NADP(+).
50112	inositol 2-dehydrogenase activity	F	Catalysis of the reaction: myo-inositol + NAD(+) = 2,4,6/3,5-pentahydroxycyclohexanone + H(+) + NADH.
50113	inositol oxygenase activity	F	Catalysis of the reaction: myo-inositol + O(2) = D-glucuronate + H(2)O + H(+).
50114	myo-inosose-2 dehydratase activity	F	Catalysis of the reaction: 2,4,6/3,5-pentahydroxycyclohexanone = 3D-3,5/4-trihydroxycyclohexane-1,2-dione + H(2)O.
50115	myosin-light-chain-phosphatase activity	F	Catalysis of the reaction: myosin light-chain phosphate + H2O = myosin light chain + phosphate.
50116	N,N-dimethylformamidase activity	F	Catalysis of the reaction: N,N-dimethylformamide + H(2)O = dimethylamine + formate.
50117	N-acetyl-beta-alanine deacetylase activity	F	Catalysis of the reaction: N-acetyl-beta-alanine + H(2)O = beta-alanine + acetate.
50118	N-acetyldiaminopimelate deacetylase activity	F	Catalysis of the reaction: N-acetyl-LL-2,6-diaminopimelate + H(2)O = LL-2,6-diaminopimelate + acetate.
50119	N-acetylglucosamine deacetylase activity	F	Catalysis of the reaction: N-acetyl-D-glucosamine + H(2)O = D-glucosamine + acetate.
50120	N-acetylhexosamine 1-dehydrogenase activity	F	Catalysis of the reaction: N-acetyl-D-glucosamine + H(2)O + NAD(+) = N-acetyl-D-glucosaminate + 2 H(+) + NADH.
50121	N-acylglucosamine 2-epimerase activity	F	Catalysis of the reaction: N-acyl-D-glucosamine = N-acyl-D-mannosamine.
50122	N-acylhexosamine oxidase activity	F	Catalysis of the reaction: N-acetyl-D-glucosamine + H(2)O + O(2) = N-acetyl-D-glucosaminate + H(2)O(2) + H(+).
50123	N-acylmannosamine 1-dehydrogenase activity	F	Catalysis of the reaction: N-acyl-D-mannosamine + NAD(+) = N-acyl-D-mannosaminolactone + H(+) + NADH.
50124	N-acylneuraminate-9-phosphatase activity	F	Catalysis of the reaction: N-acylneuraminate 9-phosphate + H2O = N-acylneuraminate + phosphate.
50125	N-benzyloxycarbonylglycine hydrolase activity	F	Catalysis of the reaction: N-benzyloxycarbonylglycine + H(2)O + H(+) = benzyl alcohol + CO(2) + glycine.
50126	N-carbamoylputrescine amidase activity	F	Catalysis of the reaction: N-carbamoylputrescine + H(2)O + 2 H(+) = CO(2) + NH(4)(+) + putrescine.
50127	N-carbamoylsarcosine amidase activity	F	Catalysis of the reaction: N-carbamoylsarcosine + H(2)O + 2 H(+) = CO(2) + NH(4)(+) + sarcosine.
50128	N-feruloylglycine deacylase activity	F	Catalysis of the reaction: N-feruloylglycine + H(2)O = ferulate + glycine.
50129	N-formylglutamate deformylase activity	F	Catalysis of the reaction: N-formyl-L-glutamate + H(2)O = L-glutamate + formate.
50130	N-methyl-2-oxoglutaramate hydrolase activity	F	Catalysis of the reaction: N-methyl-2-oxoglutaramate + H(2)O = 2-oxoglutarate + methylammonium.
50131	N-methyl-L-amino-acid oxidase activity	F	Catalysis of the reaction: an N-methyl-L-amino acid + H2O + O2 = an L-amino acid + formaldehyde + H2O2.
50132	N-methylalanine dehydrogenase activity	F	Catalysis of the reaction: N-methyl-L-alanine + H(2)O + NADP(+) = H(+) + methylammonium + NADPH + pyruvate.
50133	N6-hydroxylysine O-acetyltransferase activity	F	Catalysis of the reaction: N(6)-hydroxy-L-lysine + acetyl-CoA = N(6)-acetyl-N(6)-hydroxy-L-lysine + CoA.
50134	N6-methyl-lysine oxidase activity	F	Catalysis of the reaction: N(6)-methyl-L-lysine + H(2)O + O(2) = L-lysine + formaldehyde + H(2)O(2).
50135	NAD(P)+ nucleosidase activity	F	Catalysis of the reaction: NAD(P)+ + H2O = ADP-ribose(P) + nicotinamide.
50136	NADH dehydrogenase (quinone) activity	F	Catalysis of the reaction: NADH + H+ + a quinone = NAD+ + a quinol.
50137	NADPH peroxidase activity	F	Catalysis of the reaction: H(2)O(2) + H(+) + NADPH = 2 H(2)O + NADP(+).
50138	nicotinate dehydrogenase activity	F	Catalysis of the reaction: H(2)O + NADP(+) + nicotinate = 6-hydroxynicotinate + H(+) + NADPH.
50139	nicotinate-N-glucosyltransferase activity	F	Catalysis of the reaction: nicotinate + UDP-D-glucose = N-(beta-D-glucosyl)nicotinate + UDP.
50140	nitrate reductase (cytochrome) activity	F	Catalysis of the reaction: ferrocytochrome + nitrate = ferricytochrome + nitrite.
50141	nitroethane oxidase activity	F	Catalysis of the reaction: nitroethane + H2O + O2 = acetaldehyde + nitrite + H2O2.
50142	nitrogenase (flavodoxin) activity	F	Catalysis of the reaction: 6 reduced flavodoxin + 6 H+ + N2 + n ATP = 6 oxidized flavodoxin + 2 NH3 + n ADP + n phosphate.
50143	nocardicin-A epimerase activity	F	Catalysis of the reaction: isonocardicin A = nocardicin A.
50144	nucleoside deoxyribosyltransferase activity	F	Catalysis of the reaction: 2-deoxy-D-ribosyl-base1 + base2 = 2-deoxy-D-ribosyl-base2 + base1.
50145	nucleoside phosphate kinase activity	F	Catalysis of the reaction: ATP + nucleoside phosphate = ADP + nucleoside diphosphate.
50146	nucleoside phosphotransferase activity	F	Catalysis of the reaction: a nucleotide + a 2'-deoxynucleoside = a nucleoside + a 2'-deoxynucleoside 5'-monophosphate.
50147	nucleoside ribosyltransferase activity	F	Catalysis of the reaction: D-ribosyl-base1 + base2 = D-ribosyl-base2 + base1.
50148	nucleotide diphosphokinase activity	F	Catalysis of the reaction: ATP + nucleoside 5'-phosphate = AMP + 5'-phosphonucleoside 3'-diphosphate.
50149	o-aminophenol oxidase activity	F	Catalysis of the reaction: 2 2-aminophenol + 3 O2 = 2 isophenoxazine + 6 H2O.
50150	o-pyrocatechuate decarboxylase activity	F	Catalysis of the reaction: 2,3-dihydroxybenzoate + H(+) = catechol + CO(2).
50151	oleate hydratase activity	F	Catalysis of the reaction: (R)-10-hydroxystearate = H(2)O + oleate.
50152	omega-amidase activity	F	Catalysis of the reaction: a monoamide of a dicarboxylic acid + H2O = a dicarboxylate + NH3.
50153	omega-hydroxydecanoate dehydrogenase activity	F	Catalysis of the reaction: 10-hydroxydecanoate + NAD(+) = 10-oxodecanoate + H(+) + NADH.
50154	opheline kinase activity	F	Catalysis of the reaction: ATP + guanidinoethyl methyl phosphate = N'-phosphoguanidinoethyl methylphosphate + ADP + 2 H(+).
50155	ornithine(lysine) transaminase activity	F	Catalysis of the reaction: 2-oxoglutarate + L-ornithine = H2O + L-glutamate + 3,4-dihydro-2H-pyrrole-2-carboxylate.
50156	ornithine N-benzoyltransferase activity	F	Catalysis of the reaction: L-ornithine + 2 benzoyl-CoA = N(2),N(5)-dibenzoyl-L-ornithine + 2 CoA + 2 H(+).
50157	ornithine racemase activity	F	Catalysis of the reaction: L-ornithine = D-ornithine.
50158	orotate reductase (NADPH) activity	F	Catalysis of the reaction: (S)-dihydroorotate + NADP(+) = H(+) + NADPH + orotate.
50159	orsellinate decarboxylase activity	F	Catalysis of the reaction: o-orsellinate + H(+) = CO(2) + orcinol.
50160	orsellinate-depside hydrolase activity	F	Catalysis of the reaction: H(2)O + orsellinate depside = 2 o-orsellinate + H(+).
50161	succinyl-CoA:oxalate CoA-transferase	F	Catalysis of the reaction: oxalate + succinyl-CoA = oxalyl-CoA + succinate.
50162	oxalate oxidase activity	F	Catalysis of the reaction: 2 H(+) + O(2) + oxalate = 2 CO(2) + H(2)O(2).
50163	oxaloacetate tautomerase activity	F	Catalysis of the reaction: oxaloacetate = <stereo>enol</stereo>-oxaloacetate.
50164	oxoglutarate dehydrogenase (NADP+) activity	F	Catalysis of the reaction: 2-oxoglutarate + CoA + NADP(+) = CO(2) + NADPH + succinyl-CoA.
50165	pantetheine kinase activity	F	Catalysis of the reaction: ATP + pantetheine = ADP + pantetheine 4'-phosphate.
50166	pantoate 4-dehydrogenase activity	F	Catalysis of the reaction: (R)-pantoate + NAD(+) = (R)-4-dehydropantoate + H(+) + NADH.
50167	pantothenoylcysteine decarboxylase activity	F	Catalysis of the reaction: N-[(R)-pantothenoyl]-L-cysteine + H(+) = (R)-pantetheine + CO(2).
50168	pentanamidase activity	F	Catalysis of the reaction: H(2)O + pentanamide = NH(4)(+) + valerate.
50169	peptide-tryptophan 2,3-dioxygenase activity	F	Catalysis of the reaction: peptide tryptophan + O2 = peptide formylkynurenine.
50170	peptidyl-glutaminase activity	F	Catalysis of the reaction: alpha-N-peptidyl-L-glutamine + H2O = alpha-N-peptidyl-L-glutamate + NH3.
50171	phenol beta-glucosyltransferase activity	F	Catalysis of the reaction: UDP-glucose + a phenol = UDP + an aryl beta-D-glucoside.
50172	phenylalanine 2-monooxygenase activity	F	Catalysis of the reaction: L-phenylalanine + O(2) = 2-phenylacetamide + CO(2) + H(2)O.
50173	phenylalanine adenylyltransferase activity	F	Catalysis of the reaction: L-phenylalanine + ATP = N-adenylyl-L-phenylalanine + diphosphate + 2 H(+).
50174	phenylalanine decarboxylase activity	F	Catalysis of the reaction: L-phenylalanine = phenylethylamine + CO2.
50175	phenylalanine dehydrogenase activity	F	Catalysis of the reaction: L-phenylalanine + H2O + NAD+ = phenylpyruvate + NH3 + NADH.
50176	phenylalanine N-acetyltransferase activity	F	Catalysis of the reaction: L-phenylalanine + acetyl-CoA = N-acetyl-L-phenylalanine + CoA + H(+).
50177	phenylpyruvate decarboxylase activity	F	Catalysis of the reaction: phenylpyruvate = phenylacetaldehyde + CO2.
50178	phenylpyruvate tautomerase activity	F	Catalysis of the reaction: keto-phenylpyruvate = enol-phenylpyruvate.
50179	phenylserine aldolase activity	F	Catalysis of the reaction: L-threo-3-phenylserine = benzaldehyde + glycine.
50180	phloretin hydrolase activity	F	Catalysis of the reaction: H(2)O + phloretin = H(+) + phloretate + phloroglucinol.
50181	phorbol-diester hydrolase activity	F	Catalysis of the reaction: H(2)O + phorbol 12,13-dibutanoate = butanoate + H(+) + phorbol 13-butanoate.
50182	phosphate butyryltransferase activity	F	Catalysis of the reaction: butanoyl-CoA + phosphate = butanoyl phosphate + CoA.
50183	phosphatidylcholine 12-monooxygenase activity	F	Catalysis of the reaction: 1-acyl-2-oleoyl-sn-glycero-3-phosphocholine + H(+) + NADH + O(2) = 1-acyl-2-[(S)-12-hydroxyoleoyl]-sn-glycero-3-phosphocholine + H(2)O + NAD(+).
50184	phosphatidylcholine desaturase activity	F	Catalysis of the reaction: 1-acyl-2-oleoyl-sn-glycero-3-phosphocholine + NAD(+) = 1-acyl-2-linoleoyl-sn-glycero-3-phosphocholine + H(+) + NADH.
50185	phosphatidylinositol deacylase activity	F	Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol + H(2)O = 1-acyl-sn-glycero-3-phospho-D-myo-inositol + a carboxylate + H(+).
50186	phosphoadenylylsulfatase activity	F	Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + H2O = adenosine 3',5'-bisphosphate + sulfate.
50187	phosphoamidase activity	F	Catalysis of the reaction: N-phosphocreatine + H(2)O = creatine + phosphate.
50188	phosphoenolpyruvate mutase activity	F	Catalysis of the reaction: phosphoenolpyruvate = 3-phosphonopyruvate.
50189	phosphoenolpyruvate phosphatase activity	F	Catalysis of the reaction: H(2)O + phosphoenolpyruvate = phosphate + pyruvate.
50190	phosphoglucokinase activity	F	Catalysis of the reaction: alpha-D-glucose 1-phosphate + ATP = alpha-D-glucose 1,6-bisphosphate + ADP + 2 H(+).
50191	phosphoglycerate kinase (GTP) activity	F	Catalysis of the reaction: 3-phospho-D-glycerate + GTP = 3-phospho-D-glyceroyl phosphate + GDP + H(+).
50192	phosphoglycerate phosphatase activity	F	Catalysis of the reaction: 2-phospho-D-glycerate + H(2)O = D-glycerate + phosphate.
50193	phosphoketolase activity	F	Catalysis of the reaction: D-xylulose 5-phosphate + phosphate = acetyl phosphate + D-glyceraldehyde 3-phosphate + H2O.
50194	phosphonoacetaldehyde hydrolase activity	F	Catalysis of the reaction: H(2)O + phosphonoacetaldehyde = acetaldehyde + H(+) + phosphate.
50195	phosphoribokinase activity	F	Catalysis of the reaction: D-ribose 5-phosphate + ATP = D-ribose 1,5-diphosphate + ADP + 2 H(+).
50196	[phosphorylase] phosphatase activity	F	Catalysis of the reaction: [phosphorylase a] + 4 H2O = 2 [phosphorylase b] + 4 phosphate.
50197	phytanate-CoA ligase activity	F	Catalysis of the reaction: ATP + CoA + phytanate = AMP + diphosphate + H(+) + phytanoyl-CoA.
50198	pinosylvin synthase activity	F	Catalysis of the reaction: trans-cinnamoyl-CoA + 3 H(+) + 3 malonyl-CoA = 4 CO(2) + 4 CoA + pinosylvin.
50199	piperidine N-piperoyltransferase activity	F	Catalysis of the reaction: (E,E)-piperoyl-CoA + piperidine = N-[(E,E)-piperoyl]piperidine + CoA + H(+).
50200	plasmalogen synthase activity	F	Catalysis of the reaction: acyl-CoA + 1-O-alk-1-enyl-glycero-3-phosphocholine = CoA + plasmenylcholine.
50201	fucokinase activity	F	Catalysis of the reaction: L-fucose + ATP = beta-L-fucose 1-phosphate + ADP + 2 H(+).
50202	octopamine dehydratase activity	F	Catalysis of the reaction: 1-(4-hydroxyphenyl)-2-aminoethanol = (4-hydroxyphenyl)acetaldehyde + NH(4)(+).
50203	oxalate-CoA ligase activity	F	Catalysis of the reaction: ATP + CoA + oxalate = AMP + diphosphate + H(+) + oxalyl-CoA.
50204	oxalomalate lyase activity	F	Catalysis of the reaction: 3-oxalomalate = glyoxylate + oxaloacetate.
50205	oxamate carbamoyltransferase activity	F	Catalysis of the reaction: carbamoyl phosphate + oxamate = oxalurate + phosphate.
50206	oximinotransferase activity	F	Catalysis of the reaction: 2-(hydroxyimino)propanoate + acetone = acetone oxime + pyruvate.
50207	plasmanylethanolamine desaturase activity	F	Catalysis of the reaction: O-1-alkyl-2-acyl-sn-glycero-3-phosphoethanolamine + donor-H2 + O2 = O-1-alk-1-enyl-2-acyl-sn-glycero-3-phosphoethanolamine + acceptor + 2 H2O.
50208	polysialic-acid O-acetyltransferase activity	F	Catalysis of the reaction: acetyl-CoA + an alpha-2,8-linked polymer of sialic acid = CoA + polysialic acid acetylated at O-7 or O-9.
50209	polyvinyl-alcohol oxidase activity	F	Catalysis of the reaction: polyvinyl alcohol + O2 = oxidized polyvinyl alcohol + H2O2.
50210	prenyl-diphosphatase activity	F	Catalysis of the reaction: prenyl diphosphate + H2O = prenol + diphosphate.
50211	procollagen galactosyltransferase activity	F	Catalysis of the reaction: UDP-galactose + procollagen 5-hydroxy-L-lysine = UDP + procollagen 5-(D-galactosyloxy)-L-lysine.
50212	progesterone 11-alpha-monooxygenase activity	F	Catalysis of the reaction: AH(2) + O(2) + progesterone = 11alpha-hydroxyprogesterone + A + H(2)O.
50213	progesterone 5-alpha-reductase activity	F	Catalysis of the reaction: 5-alpha-pregnan-3,20-dione + NADP+ = progesterone + NADPH.
50214	progesterone monooxygenase activity	F	Catalysis of the reaction: AH(2) + O(2) + progesterone = A + H(2)O + testosterone acetate.
50215	propanediol dehydratase activity	F	Catalysis of the reaction: propane-1,2-diol = H(2)O + propanal.
50216	propanediol-phosphate dehydrogenase activity	F	Catalysis of the reaction: NAD(+) + propane-1,2-diol 1-phosphate = H(+) + hydroxyacetone phosphate + NADH.
50217	propioin synthase activity	F	Catalysis of the reaction: 4-hydroxyhexan-3-one = 2 propanal.
50218	propionate-CoA ligase activity	F	Catalysis of the reaction: ATP + propanoate + CoA = AMP + diphosphate + propanoyl-CoA.
50219	prostaglandin-A1 delta-isomerase activity	F	Catalysis of the reaction: prostaglandin A1 = prostaglandin C1.
50220	prostaglandin-E synthase activity	F	Catalysis of the reaction: prostaglandin H(2) = prostaglandin E(2).
50221	prostaglandin-E2 9-reductase activity	F	Catalysis of the reaction: (5Z,13E)-(15S)-9-alpha,11-alpha,15-trihydroxyprosta-5,13-dienoate + NADP+ = (5Z,13E)-(15S)-11-alpha,15-dihydroxy-9-oxoprosta-5,13-dienoate + NADPH.
50223	protocatechuate decarboxylase activity	F	Catalysis of the reaction: 3,4-dihydroxybenzoate + H(+) = catechol + CO(2).
50224	prunasin beta-glucosidase activity	F	Catalysis of the reaction: (R)-prunasin + H(2)O = D-glucose + mandelonitrile.
50225	pseudouridine kinase activity	F	Catalysis of the reaction: ATP + pseudouridine = ADP + 2 H(+) + pseudouridine 5'-phosphate.
50226	psychosine sulfotransferase activity	F	Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + galactosylsphingosine = adenosine 3',5'-bisphosphate + psychosine sulfate.
50227	pteridine oxidase activity	F	Catalysis of the reaction: 2-amino-4-hydroxypteridine + O2 = 2-amino-4,7-dihydroxypteridine + unknown.
50228	pterin deaminase activity	F	Catalysis of the reaction: 2-amino-4-hydroxypteridine + H2O = 2,4-dihydroxypteridine + NH3.
50229	pterocarpin synthase activity	F	Catalysis of the reaction: medicarpin + NADP+ = vestitone + NADPH.
50230	purine imidazole-ring cyclase activity	F	Catalysis of the reaction: DNA 4,6-diamino-5-formamidopyrimidine = DNA adenine + H2O.
50231	putrescine carbamoyltransferase activity	F	Catalysis of the reaction: carbamoyl phosphate + putrescine = N-carbamoylputrescine + H(+) + phosphate.
50232	putrescine oxidase activity	F	Catalysis of the reaction: putrescine + O2 + H2O = 4-aminobutanal + NH3 + H2O2.
50233	pyranose oxidase activity	F	Catalysis of the reaction: D-glucose + O(2) = 2-dehydro-D-glucose + H(2)O(2).
50234	pyrazolylalanine synthase activity	F	Catalysis of the reaction: L-serine + pyrazole = 3-(pyrazol-1-yl)-L-alanine + H(2)O.
50235	pyridoxal 4-dehydrogenase activity	F	Catalysis of the reaction: NAD(+) + pyridoxal = 4-pyridoxolactone + H(+) + NADH.
50236	pyridoxine:NADP 4-dehydrogenase activity	F	Catalysis of the reaction: NADP(+) + pyridoxine = H(+) + NADPH + pyridoxal.
50237	pyridoxine 4-oxidase activity	F	Catalysis of the reaction: pyridoxine + O2 = pyridoxal + H2O2.
50238	pyridoxine 5-dehydrogenase activity	F	Catalysis of the reaction: pyridoxine + acceptor = isopyridoxal + reduced acceptor.
50239	pyrithiamine deaminase activity	F	Catalysis of the reaction: 1-(4-amino-2-methylpyrimid-5-ylmethyl)-3-(beta-hydroxyethyl)-2-methylpyridinium bromide + H2O = 1-(4-hydroxy-2-methylpyrimid-5-ylmethyl)-3-(beta-hydroxyethyl)-2-methylpyridinium bromide + NH3.
50240	pyrogallol 1,2-oxygenase activity	F	Catalysis of the reaction: O(2) + pyrogallol = (Z)-5-oxohex-2-enedioate + 2 H(+).
50241	pyrroline-2-carboxylate reductase activity	F	Catalysis of the reaction: L-proline + NAD(P)+ = 1-pyrroline-2-carboxylate + NAD(P)H + H+.
50242	pyruvate, phosphate dikinase activity	F	Catalysis of the reaction: ATP + phosphate + pyruvate = AMP + diphosphate + 2 H(+) + phosphoenolpyruvate.
50243	pyruvate dehydrogenase (NADP+) activity	F	Catalysis of the reaction: CoA + NADP(+) + pyruvate = acetyl-CoA + CO(2) + NADPH.
50244	pyruvate oxidase (CoA-acetylating) activity	F	Catalysis of the reaction: CoA + H(+) + O(2) + pyruvate = acetyl-CoA + CO(2) + H(2)O(2).
50245	quercitrinase activity	F	Catalysis of the reaction: H(2)O + quercitrin = L-rhamnose + quercetin.
50246	questin monooxygenase activity	F	Catalysis of the reaction: H(+) + NADPH + O(2) + questin = demethylsulochrin + NADP(+).
50247	raucaffricine beta-glucosidase activity	F	Catalysis of the reaction: H(2)O + raucaffricine = D-glucose + vomilenine.
50248	Renilla-luciferin 2-monooxygenase activity	F	Catalysis of the reaction: Renilla luciferin + O2 = oxidized Renilla luciferin + CO2 + light.
50249	Renilla-luciferin sulfotransferase activity	F	Catalysis of the reaction: 3'-phospho-5'-adenylyl sulfate + Renilla luciferin = adenosine 3',5'-diphosphate + H(+) + luciferyl sulfate.
50250	retinal oxidase activity	F	Catalysis of the reaction: retinal + O2 + H2O = retinoate + H2O2.
50251	retinol isomerase activity	F	Catalysis of the reaction: all-trans-retinol = 11-cis-retinol.
50252	retinol O-fatty-acyltransferase activity	F	Catalysis of the reaction: acyl-CoA + retinol = CoA + retinyl ester.
50253	retinyl-palmitate esterase activity	F	Catalysis of the reaction: retinyl palmitate + H2O = retinol + palmitate + H+.
50254	rhodopsin kinase activity	F	Catalysis of the reaction: ATP + rhodopsin = ADP + phosphorhodopsin.
50255	ribitol 2-dehydrogenase activity	F	Catalysis of the reaction: D-ribitol + NAD(+) = D-ribulose + H(+) + NADH.
50256	ribitol-5-phosphate 2-dehydrogenase activity	F	Catalysis of the reaction: D-ribitol 5-phosphate + NAD(P)+ = D-ribulose 5-phosphate + NAD(P)H + H+.
50257	riboflavin phosphotransferase activity	F	Catalysis of the reaction: alpha-D-glucose 1-phosphate + riboflavin = D-glucose + FMN.
50258	riboflavinase activity	F	Catalysis of the reaction: H(2)O + H(+) + riboflavin = D-ribitol + lumichrome.
50259	ribose 1-dehydrogenase (NADP+) activity	F	Catalysis of the reaction: H(2)O + NADP(+) + ribofuranose = D-ribonate + 2 H(+) + NADPH.
50260	ribose-5-phosphate-ammonia ligase activity	F	Catalysis of the reaction: D-ribose 5-phosphate + ATP + NH(4)(+) = 5-phospho-D-ribosylamine + ADP + 2 H(+) + phosphate.
50261	ribose isomerase activity	F	Catalysis of the reaction: ribofuranose = D-ribulose.
50262	ribosylnicotinamide kinase activity	F	Catalysis of the reaction: N-ribosylnicotinamide + ATP = ADP + 2 H(+) + nicotinamide mononucleotide.
50263	ribosylpyrimidine nucleosidase activity	F	Catalysis of the reaction: an N-D-ribosylpyrimidine + H2O = D-ribose + a pyrimidine.
50264	rifamycin-B oxidase activity	F	Catalysis of the reaction: 2 H(+) + O(2) + rifamycin B = H(2)O(2) + rifamycin O.
50265	RNA uridylyltransferase activity	F	Catalysis of the reaction: UTP + RNA(n) = diphosphate + RNA(n+1).
50266	rosmarinate synthase activity	F	Catalysis of the reaction: caffeoyl-CoA + 3-(3,4-dihydroxyphenyl)lactate = CoA + rosmarinate.
50267	rubber cis-polyprenylcistransferase activity	F	Catalysis of the reaction: poly-cis-polyprenyl diphosphate + isopentenyl diphosphate = diphosphate + a poly-cis-polyprenyl diphosphate longer by one C5 unit.
50268	coniferyl-alcohol dehydrogenase activity	F	Catalysis of the reaction: coniferyl alcohol + NADP+ = coniferyl aldehyde + NADPH.
50269	coniferyl-aldehyde dehydrogenase activity	F	Catalysis of the reaction: coniferyl aldehyde + H2O + NAD(P)+ = ferulate + NAD(P)H + H+.
50270	S-adenosylhomocysteine deaminase activity	F	Catalysis of the reaction: S-adenosyl-L-homocysteine + H(2)O + H(+) = S-inosyl-L-homocysteine + NH(4)(+).
50271	S-alkylcysteine lyase activity	F	Catalysis of the reaction: an S-alkyl-L-cysteine + H2O = an alkyl thiol + NH3 + pyruvate.
50272	S-carboxymethylcysteine synthase activity	F	Catalysis of the reaction: 3-chloro-L-alanine + thioglycolate = S-carboxymethyl-L-cysteine + chloride + H(+).
50273	S-succinylglutathione hydrolase activity	F	Catalysis of the reaction: S-succinylglutathione + H(2)O = glutathione + H(+) + succinate.
50274	salicyl-alcohol beta-D-glucosyltransferase activity	F	Catalysis of the reaction: salicyl alcohol + UDP-D-glucose = H(+) + salicin + UDP.
50275	scopoletin glucosyltransferase activity	F	Catalysis of the reaction: scopoletin + UDP-D-glucose = H(+) + scopolin + UDP.
50276	scyllo-inosamine 4-kinase activity	F	Catalysis of the reaction: 1-amino-1-deoxy-scyllo-inositol + ATP = 1-amino-1-deoxy-scyllo-inositol 4-phosphate + ADP + 2 H(+).
50277	sedoheptulokinase activity	F	Catalysis of the reaction: ATP + sedoheptulose = ADP + 2 H(+) + sedoheptulose 7-phosphate.
50278	sedoheptulose-bisphosphatase activity	F	Catalysis of the reaction: sedoheptulose 1,7-bisphosphate + H2O = sedoheptulose 7-phosphate + phosphate.
50279	sepiapterin deaminase activity	F	Catalysis of the reaction: sepiapterin + H2O = xanthopterin-B2 + NH3.
50280	sequoyitol dehydrogenase activity	F	Catalysis of the reaction: 1D-5-O-methyl-myo-inositol + NAD(+) = 2D-5-O-methyl-2,3,5/4,6-pentahydroxycyclohexanone + H(+) + NADH.
50281	serine-glyoxylate transaminase activity	F	Catalysis of the reaction: L-serine + glyoxylate = 3-hydroxypyruvate + glycine.
50282	serine 2-dehydrogenase activity	F	Catalysis of the reaction: L-serine + H2O + NAD+ = 3-hydroxypyruvate + NH3 + NADH.
50283	serine-sulfate ammonia-lyase activity	F	Catalysis of the reaction: L-serine O-sulfate + H2O = pyruvate + NH3 + sulfate.
50284	sinapate 1-glucosyltransferase activity	F	Catalysis of the reaction: UDP-glucose + sinapate = UDP + 1-sinapoyl-D-glucose.
50285	sinapine esterase activity	F	Catalysis of the reaction: O-sinapoylcholine + H(2)O = choline + H(+) + sinapate.
50286	sorbitol-6-phosphatase activity	F	Catalysis of the reaction: D-glucitol 6-phosphate + H(2)O = D-glucitol + phosphate.
50287	sorbose 5-dehydrogenase (NADP+) activity	F	Catalysis of the reaction: L-sorbose + NADP(+) = 5-dehydro-D-fructose + H(+) + NADPH.
50288	sorbose dehydrogenase activity	F	Catalysis of the reaction: L-sorbose + A = 5-dehydro-D-fructose + AH(2).
50289	spermidine dehydrogenase activity	F	Catalysis of the reaction: spermidine + acceptor + H2O = 1,3-diaminopropane + 4-aminobutanal + reduced acceptor.
50290	sphingomyelin phosphodiesterase D activity	F	Catalysis of the reaction: H(2)O + sphingomyelin = ceramide 1-phosphate + choline + H(+).
50291	sphingosine N-acyltransferase activity	F	Catalysis of the reaction: acyl-CoA + sphingosine = CoA + N-acylsphingosine.
50292	steroid 9-alpha-monooxygenase activity	F	Catalysis of the reaction: AH(2) + O(2) + pregna-4,9(11)-diene-3,20-dione = 9,11alpha-epoxypregn-4-ene-3,20-dione + A + H(2)O.
50293	steroid-lactonase activity	F	Catalysis of the reaction: H(2)O + testololactone = H(+) + testolate.
50294	steroid sulfotransferase activity	F	Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + a phenolic steroid = adenosine 3',5'-bisphosphate + steroid O-sulfate.
50295	steryl-beta-glucosidase activity	F	Catalysis of the reaction: cholesteryl-beta-D-glucoside + H(2)O = D-glucose + cholesterol.
50296	stipitatonate decarboxylase activity	F	Catalysis of the reaction: H(2)O + stipitatonate = CO(2) + H(+) + stipitatate.
50297	stizolobate synthase activity	F	Catalysis of the reaction: 3,4-dihydroxy-L-phenylalanine + O2 = 4-(L-alanin-3-yl)-2-hydroxy-cis,cis-muconate 6-semialdehyde.
50298	stizolobinate synthase activity	F	Catalysis of the reaction: 3,4-dihydroxy-L-phenylalanine + O2 = 5-(L-alanin-3-yl)-2-hydroxy-cis,cis-muconate 6-semialdehyde.
50299	streptomycin 3''-kinase activity	F	Catalysis of the reaction: ATP + streptomycin = ADP + 2 H(+) + streptomycin 3''-phosphate.
50300	aminoglycoside 6-kinase activity	F	Catalysis of the reaction: ATP + streptomycin = ADP + 2 H(+) + streptomycin 6-phosphate.
50301	streptomycin-6-phosphatase activity	F	Catalysis of the reaction: H(2)O + streptomycin 6-phosphate = phosphate + streptomycin.
50302	indole-3-acetaldehyde oxidase activity	F	Catalysis of the reaction: (indol-3-yl)acetaldehyde + H(2)O + O(2) = (indol-3-yl)acetate + H(2)O(2) + H(+).
50303	lysine 6-dehydrogenase activity	F	Catalysis of the reaction: H2O + NAD+ + L-lysine = NH3 + NADH + allysine.
50304	nitrous-oxide reductase activity	F	Catalysis of the reaction: H(2)O + 2 cytochrome c + nitrogen = 2 reduced cytochrome c + nitrous oxide.
50305	strombine dehydrogenase activity	F	Catalysis of the reaction: N-(carboxymethyl)-D-alanine + H(2)O + NAD(+) = glycine + H(+) + NADH + pyruvate.
50306	sucrose 1F-fructosyltransferase activity	F	Catalysis of the reaction: 2 sucrose = D-glucose + 1F-beta-D-fructosylsucrose.
50307	sucrose-phosphate phosphatase activity	F	Catalysis of the reaction: sucrose 6F-phosphate + H2O = sucrose + phosphate.
50308	sugar-phosphatase activity	F	Catalysis of the reaction: sugar phosphate + H2O = sugar + phosphate.
50309	sugar-terminal-phosphatase activity	F	Catalysis of the reaction: H2O + sugar phosphorylated on the terminal carbon = a sugar + phosphate.
50310	sulfite dehydrogenase activity	F	Catalysis of the reaction: sulfite + 2 ferricytochrome c + H2O = sulfate + 2 ferrocytochrome c.
50311	sulfite reductase (ferredoxin) activity	F	Catalysis of the reaction: hydrogen sulfide + 3 oxidized ferredoxin + 3 H2O = sulfite + 3 reduced ferredoxin.
50312	sulfoacetaldehyde lyase activity	F	Catalysis of the reaction: 2-sulfoacetaldehyde + H2O = acetate + sulfite.
50313	sulfur dioxygenase activity	F	Catalysis of the reaction: sulfur + O2 + H2O = sulfite.
50314	sym-norspermidine synthase activity	F	Catalysis of the reaction: 1,3-diaminopropane + S-adenosylmethioninamine = S-methyl-5'-thioadenosine + bis(3-aminopropyl)amine + H(+).
50315	synephrine dehydratase activity	F	Catalysis of the reaction: synephrine = (4-hydroxyphenyl)acetaldehyde + methylammonium.
50316	T2-induced deoxynucleotide kinase activity	F	Catalysis of the reactions: ATP + dGMP = ADP + dGDP, and ATP + dTMP = ADP + dTDP.
50317	tagatose kinase activity	F	Catalysis of the reaction: D-tagatose + ATP = D-tagatose 6-phosphate + ADP + 2 H(+).
50318	tannase activity	F	Catalysis of the reaction: digallate + H(2)O = 2 gallate + H(+).
50319	tartrate decarboxylase activity	F	Catalysis of the reaction: L-tartrate + H(+) = D-glycerate + CO(2).
50320	tartrate epimerase activity	F	Catalysis of the reaction: L-tartrate = (2R,3S)-tartrate.
50321	tau-protein kinase activity	F	Catalysis of the reaction: ATP + tau-protein = ADP + O-phospho-tau-protein.
50322	taurine-2-oxoglutarate transaminase activity	F	Catalysis of the reaction: taurine + 2-oxoglutarate = sulfoacetaldehyde + L-glutamate.
50323	taurine dehydrogenase activity	F	Catalysis of the reaction: A + H(2)O + taurine = AH(2) + NH(4)(+) + sulfoacetaldehyde.
50324	taurocyamine kinase activity	F	Catalysis of the reaction: ATP + taurocyamine = N-phosphotaurocyamine + ADP + 2 H(+).
50325	tauropine dehydrogenase activity	F	Catalysis of the reaction: H(2)O + NAD(+) + tauropine = H(+) + NADH + pyruvate + taurine.
50326	taxifolin 8-monooxygenase activity	F	Catalysis of the reaction: taxifolin + NAD(P)H + H+ + O2 = 2,3-dihydrogossypetin + NAD(P)+ + H2O.
50328	tetrahydroberberine oxidase activity	F	Catalysis of the reaction: (S)-tetrahydroberberine + 2 O2 = berberine + 2 H2O2.
50329	tetrahydroxypteridine cycloisomerase activity	F	Catalysis of the reaction: tetrahydroxypteridine = H(+) + xanthine-8-carboxylate.
50330	theanine hydrolase activity	F	Catalysis of the reaction: N(5)-ethyl-L-glutamine + H(2)O = L-glutamate + ethylamine.
50331	thiamine-diphosphate kinase activity	F	Catalysis of the reaction: ATP + thiamin diphosphate = ADP + thiamin triphosphate.
50332	thiamine pyridinylase activity	F	Catalysis of the reaction: pyridine + thiamine = 5-(2-hydroxyethyl)-4-methylthiazole + heteropyrithiamine.
50333	thiamin-triphosphatase activity	F	Catalysis of the reaction: H(2)O + thiamine triphosphate = H(+) + phosphate + thiamine diphosphate.
50334	thiaminase activity	F	Catalysis of the reaction: H(2)O + thiamine = 4-amino-5-hydroxymethyl-2-methylpyrimidine + 5-(2-hydroxyethyl)-4-methylthiazole + H(+).
50335	thiocyanate isomerase activity	F	Catalysis of the reaction: benzyl isothiocyanate = benzyl thiocyanate.
50336	thioethanolamine S-acetyltransferase activity	F	Catalysis of the reaction: acetyl-CoA + cysteamine = S-acetylcysteamine + CoA.
50337	thiosulfate-thiol sulfurtransferase activity	F	Catalysis of the reaction: thiosulfate + 2 glutathione = sulfite + glutathione disulfide + sulfide.
50338	thiosulfate dehydrogenase activity	F	Catalysis of the reaction: 2 thiosulfate + 2 ferricytochrome c = tetrathionate + 2 ferrocytochrome c.
50339	thymidine-triphosphatase activity	F	Catalysis of the reaction: dTTP + H2O = dTDP + phosphate.
50340	thymidylate 5'-phosphatase activity	F	Catalysis of the reaction: thymidylate + H2O = thymidine + phosphate.
50341	thymine dioxygenase activity	F	Catalysis of the reaction: thymine + 2-oxoglutarate + O2 = 5-hydroxymethyluracil + succinate + CO2.
50342	tocopherol O-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + gamma-tocopherol = S-adenosyl-L-homocysteine + alpha-tocopherol.
50343	trans-2-enoyl-CoA reductase (NAD+) activity	F	Catalysis of the reaction: acyl-CoA + NAD+ = trans-didehydroacyl-CoA + NADH.
50344	trans-cinnamate 2-monooxygenase activity	F	Catalysis of the reaction: trans-cinnamate + H(+) + NADPH + O(2) = 2-coumarate + H(2)O + NADP(+).
50345	trans-epoxysuccinate hydrolase activity	F	Catalysis of the reaction: trans-2,3-epoxysuccinate + H(2)O = (2R,3S)-tartrate.
50346	trans-L-3-hydroxyproline dehydratase activity	F	Catalysis of the reaction: trans-L-3-hydroxyproline = 1-pyrroline-2-carboxylate + H(2)O + H(+).
50347	trans-octaprenyltranstransferase activity	F	Catalysis of the reaction: all-trans-octaprenyl diphosphate + isopentenyl diphosphate = all-trans-nonaprenyl diphosphate + diphosphate.
50348	trehalose O-mycolyltransferase activity	F	Catalysis of the reaction: 2 alpha,alpha'-trehalose 6-mycolate = alpha,alpha'-trehalose 6,6'-bismycolate + alpha,alpha-trehalose.
50349	triacetate-lactonase activity	F	Catalysis of the reaction: H(2)O + triacetate lactone = triacetate.
50350	trihydroxystilbene synthase activity	F	Catalysis of the reaction: 3 malonyl-CoA + 4-coumaroyl-CoA = 4 CoA + 3,4',5-trihydroxy-stilbene + 4 CO2.
50351	trimetaphosphatase activity	F	Catalysis of the reaction: H(2)O + trimetaphosphate = 2 H(+) + triphosphate.
50352	trimethylamine-oxide aldolase activity	F	Catalysis of the reaction: H(+) + trimethylamine N-oxide = dimethylamine + formaldehyde.
50353	trimethyllysine dioxygenase activity	F	Catalysis of the reaction: 2-oxoglutarate + N(6),N(6),N(6)-trimethyl-L-lysine + O(2) = 3-hydroxy-N(6),N(6),N(6)-trimethyl-L-lysine + CO(2) + succinate.
50354	triokinase activity	F	Catalysis of the reaction: D-glyceraldehyde + ATP = D-glyceraldehyde 3-phosphate + ADP + 2 H(+).
50355	triphosphatase activity	F	Catalysis of the reaction: H(2)O + triphosphate = diphosphate + phosphate.
50356	tropine dehydrogenase activity	F	Catalysis of the reaction: NADP(+) + tropine = H(+) + NADPH + tropinone.
50357	tropinesterase activity	F	Catalysis of the reaction: atropine + H(2)O = H(+) + tropate + tropine.
50358	tropinone reductase activity	F	Catalysis of the reaction: NADP(+) + pseudotropine = H(+) + NADPH + tropinone.
50359	tropomyosin kinase activity	F	Catalysis of the reaction: ATP + tropomyosin = ADP + O-phosphotropomyosin.
50360	tryptophan 2'-dioxygenase activity	F	Catalysis of the reaction: L-tryptophan + O2 = 3-indoleglycolaldehyde + CO2 + NH3.
50361	tryptophan 2-monooxygenase activity	F	Catalysis of the reaction: L-tryptophan + O(2) = CO(2) + H(2)O + indole-3-acetamide.
50362	L-tryptophan:2-oxoglutarate aminotransferase activity	F	Catalysis of the reaction: L-tryptophan + 2-oxoglutarate = indolepyruvate + L-glutamate.
50363	tryptophan dehydrogenase activity	F	Catalysis of the reaction: L-tryptophan + NAD(P)+ = (indol-3-yl)pyruvate + NH3 + NAD(P)H + H+.
50364	tryptophan dimethylallyltransferase activity	F	Catalysis of the reaction: dimethylallyl diphosphate + L-tryptophan = diphosphate + 4-(3-methylbut-2-enyl)-L-tryptophan.
50365	tryptophanamidase activity	F	Catalysis of the reaction: L-tryptophanamide + H(2)O = L-tryptophan + NH(4)(+).
50366	tyramine N-feruloyltransferase activity	F	Catalysis of the reaction: feruloyl-CoA + tyramine = CoA + N-feruloyltyramine.
50367	tyrosine-arginine ligase activity	F	Catalysis of the reaction: L-arginine + L-tyrosine + ATP = L-tyrosyl-L-arginine + AMP + diphosphate + 2 H(+).
50368	tyrosine 2,3-aminomutase activity	F	Catalysis of the reaction: L-tyrosine = 3-amino-3-(4-hydroxyphenyl)propanoate.
50369	[tyrosine 3-monooxygenase] kinase activity	F	Catalysis of the reaction: ATP + [tyrosine-3-monooxygenase] = ADP + phospho-[tyrosine-3-monooxygenase].
50370	tyrosine N-monooxygenase activity	F	Catalysis of the reaction: tyrosine + O2 + NADPH + H+ = N-hydroxytyrosine + NADP+ + H2O.
50371	tyrosine phenol-lyase activity	F	Catalysis of the reaction: L-tyrosine + H(2)O = NH(4)(+) + phenol + pyruvate.
50372	ubiquitin-calmodulin ligase activity	F	Catalysis of the reaction: n ATP + calmodulin + n ubiquitin = n AMP + n diphosphate + ubiquitin(n)-calmodulin.
50373	UDP-arabinose 4-epimerase activity	F	Catalysis of the reaction: UDP-L-arabinose = UDP-alpha-D-xylose.
50374	UDP-galacturonate decarboxylase activity	F	Catalysis of the reaction: H(+) + UDP-alpha-D-galacturonate = CO(2) + UDP-L-arabinose.
50376	UDP-glucosamine 4-epimerase activity	F	Catalysis of the reaction: UDP-glucosamine = UDP-galactosamine.
50377	UDP-glucose 4,6-dehydratase activity	F	Catalysis of the reaction: UDP-D-glucose = H(2)O + UDP-4-dehydro-6-deoxy-D-glucose.
50378	UDP-glucuronate 4-epimerase activity	F	Catalysis of the reaction: UDP-alpha-D-glucuronate = UDP-alpha-D-galacturonate.
50379	UDP-glucuronate 5'-epimerase activity	F	Catalysis of the reaction: UDP-alpha-D-glucuronate = UDP-L-iduronate.
50380	undecaprenyl-diphosphatase activity	F	Catalysis of the reaction: all-trans-undecaprenyl diphosphate + H(2)O = all-trans-undecaprenyl phosphate + H(+) + phosphate.
50382	uracil-5-carboxylate decarboxylase activity	F	Catalysis of the reaction: H(+) + uracil 5-carboxylate = CO(2) + uracil.
50383	uracil dehydrogenase activity	F	Catalysis of the reaction: uracil + acceptor = barbiturate + reduced acceptor.
50384	urate-ribonucleotide phosphorylase activity	F	Catalysis of the reaction: 3-(beta-D-ribofuranosyl)uric acid + phosphate = alpha-D-ribose 1-phosphate + H(+) + urate.
50385	ureidoglycolate lyase activity	F	Catalysis of the reaction: (S)-ureidoglycolate = glyoxylate + urea.
50386	ureidosuccinase activity	F	Catalysis of the reaction: N-carbamoyl-L-aspartate + H(2)O + 2 H(+) = L-aspartate + CO(2) + NH(4)(+).
50387	urethanase activity	F	Catalysis of the reaction: H(2)O + H(+) + urethane = CO(2) + ethanol + NH(4)(+).
50388	uronate dehydrogenase activity	F	Catalysis of the reaction: D-galacturonate + H(2)O + NAD(+) = galactarate + 2 H(+) + NADH.
50389	uronolactonase activity	F	Catalysis of the reaction: D-glucurono-6,2-lactone + H2O = D-glucuronate.
50390	valine decarboxylase activity	F	Catalysis of the reaction: L-valine + H(+) = 2-methylpropanamine + CO(2).
50391	valine dehydrogenase (NADP) activity	F	Catalysis of the reaction: L-valine + H2O + NADP+ = 3-methyl-2-oxobutanoate + NH3 + NADPH.
50392	vicianin beta-glucosidase activity	F	Catalysis of the reaction: (R)-vicianin + H(2)O = mandelonitrile + vicianose.
50393	vinylacetyl-CoA delta-isomerase activity	F	Catalysis of the reaction: vinylacetyl-CoA = crotonoyl-CoA.
50394	viomycin kinase activity	F	Catalysis of the reaction: ATP + viomycin = ADP + O-phosphoviomycin.
50395	vitexin beta-glucosyltransferase activity	F	Catalysis of the reaction: UDP-D-glucose + vitexin = H(+) + UDP + vitexin 2''-O-beta-D-glucoside.
50396	vomifoliol 4'-dehydrogenase activity	F	Catalysis of the reaction: (6S,9R)-6-hydroxy-3-oxo-alpha-ionol + NAD(+) = (6S)-6-hydroxy-3-oxo-alpha-ionone + H(+) + NADH.
50397	Watasenia-luciferin 2-monooxygenase activity	F	Catalysis of the reaction: Watasenia luciferin + O2 = oxidized Watasenia luciferin + CO2 + light.
50398	wax-ester hydrolase activity	F	Catalysis of the reaction: a wax ester + H2O = a long-chain alcohol + a long-chain carboxylate.
50399	xanthommatin reductase activity	F	Catalysis of the reaction: 5,12-dihydroxanthommatin + NAD(+) = H(+) + NADH + xanthommatin.
50400	xylitol kinase activity	F	Catalysis of the reaction: ATP + xylitol = ADP + 2 H(+) + xylitol 5-phosphate.
50401	xylonate dehydratase activity	F	Catalysis of the reaction: D-xylonate = 2-dehydro-3-deoxy-D-arabinonate + H(2)O.
50402	xylono-1,4-lactonase activity	F	Catalysis of the reaction: D-xylono-1,4-lactone + H2O = D-xylonate.
50403	trans-zeatin O-beta-D-glucosyltransferase activity	F	Catalysis of the reaction: trans-zeatin + UDP-D-glucose = O-beta-D-glucosyl-trans-zeatin + H(+) + UDP.
50404	zeatin O-beta-D-xylosyltransferase activity	F	Catalysis of the reaction: UDP-alpha-D-xylose + zeatin = O-beta-D-xylosylzeatin + H(+) + UDP.
50405	[acetyl-CoA carboxylase] kinase activity	F	Catalysis of the reaction: ATP + [acetyl-CoA carboxylase] = ADP + [acetyl-CoA carboxylase] phosphate.
50406	[acetyl-CoA carboxylase]-phosphatase activity	F	Catalysis of the reaction: [acetyl-CoA carboxylase]-phosphate + H2O = [acetyl-CoA carboxylase] + phosphate.
50407	[glycogen-synthase-D] phosphatase activity	F	Catalysis of the reaction: [glycogen-synthase D] + H2O = [glycogen-synthase I] + phosphate.
50408	[pyruvate kinase]-phosphatase activity	F	Catalysis of the reaction: [pyruvate kinase] phosphate + H2O = [pyruvate kinase] + phosphate.
50409	indolylacetylinositol arabinosyltransferase activity	F	Catalysis of the reaction: 1L-1-O-(indol-3-yl)acetyl-myo-inositol + UDP-L-arabinose = (indol-3-yl)acetyl-myo-inositol 3-L-arabinoside + H(+) + UDP.
50410	3-oxolaurate decarboxylase activity	F	Catalysis of the reaction: 3-oxolaurate + H(+) = 2-undecanone + CO(2).
50411	agaritine gamma-glutamyltransferase activity	F	Catalysis of the reaction: agaritine + acceptor-NH2 = 4-hydroxymethylphenylhydrazine + gamma-L-glutamyl-acceptor.
50412	cinnamate beta-D-glucosyltransferase activity	F	Catalysis of the reaction: trans-cinnamate + UDP-D-glucose = 1-O-trans-cinnamoyl-beta-D-glucopyranose + UDP.
50413	D-alanine 2-hydroxymethyltransferase activity	F	Catalysis of the reaction: 5,10-methylenetetrahydrofolate + D-alanine + H(2)O = (6S)-5,6,7,8-tetrahydrofolate + 2-methylserine.
50414	formimidoylaspartate deiminase activity	F	Catalysis of the reaction: N-formimidoyl-L-aspartate + H2O = N-formyl-L-aspartate + NH3.
50415	formimidoylglutamase activity	F	Catalysis of the reaction: N-formimidoyl-L-glutamate + H(2)O = L-glutamate + formamide.
50416	formimidoylglutamate deiminase activity	F	Catalysis of the reaction: N-formimidoyl-L-glutamate + H2O = N-formyl-L-glutamate + NH3.
50417	glutamin-(asparagin-)ase activity	F	Catalysis of the reaction: H2O + L-glutamine = NH3 + L-glutamate; and H2O + L-asparagine = NH3 + L-aspartate.
50418	hydroxylamine reductase activity	F	Catalysis of the reaction: NH3 + H2O + acceptor = hydroxylamine + reduced acceptor.
50419	hydroxymandelonitrile lyase activity	F	Catalysis of the reaction: 4-hydroxymandelonitrile = 4-hydroxybenzaldehyde + hydrocyanate.
50420	maltose synthase activity	F	Catalysis of the reaction: 2 alpha-D-glucose 1-phosphate = maltose + 2 phosphate.
50421	nitrite reductase (NO-forming) activity	F	Catalysis of the reaction: nitric oxide + H2O + ferricytochrome c = nitrite + ferrocytochrome c + 2 H+.
50422	strictosidine beta-glucosidase activity	F	Catalysis of the reaction: 3alpha(S)-strictosidine + H(2)O = D-glucose + strictosidine aglycone.
50423	thiamine oxidase activity	F	Catalysis of the reaction: thiamine + 2 O2 = thiamine acetic acid + 2 H2O2.
50427	3'-phosphoadenosine 5'-phosphosulfate metabolic process	P	The chemical reactions and pathways involving 3'-phosphoadenosine 5'-phosphosulfate, a naturally occurring mixed anhydride. It is an intermediate in the formation of a variety of sulfo compounds in biological systems.
50428	3'-phosphoadenosine 5'-phosphosulfate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of 3'-phosphoadenosine 5'-phosphosulfate, a naturally occurring mixed anhydride. It is an intermediate in the formation of a variety of sulfo compounds in biological systems.
50429	calcium-dependent phospholipase C activity	F	Catalysis of the reaction: a phosphatidylcholine + H2O = 1,2-diacylglycerol + choline phosphate. This reaction requires Ca2+.
50431	transforming growth factor beta binding	F	Interacting selectively and non-covalently with TGF-beta, transforming growth factor beta, a multifunctional peptide that controls proliferation, differentiation and other functions in many cell types.
50432	catecholamine secretion	P	The regulated release of catecholamines by a cell. The catecholamines are a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine.
50433	regulation of catecholamine secretion	P	Any process that modulates the frequency, rate or extent of the regulated release of catecholamines.
50434	positive regulation of viral transcription	P	Any process that activates or increases the frequency, rate or extent of viral transcription.
50435	beta-amyloid metabolic process	P	The chemical reactions and pathways involving beta-amyloid, a glycoprotein associated with Alzheimer's disease, and its precursor, amyloid precursor protein (APP).
50436	microfibril binding	F	Interacting selectively and non-covalently with a microfibril, any small fibril occurring in biological material.
50437	(-)-endo-fenchol synthase activity	F	Catalysis of the reaction: geranyl diphosphate + H(2)O = (-)-endo-fenchol + diphosphate.
50438	2-ethylmalate synthase activity	F	Catalysis of the reaction: 2-oxobutanate + acetyl-CoA + H(2)O = (R)-2-ethylmalate + CoA + H(+).
50439	2-hydroxy-3-oxoadipate synthase activity	F	Catalysis of the reaction: 2-oxoglutarate + glyoxylate + H(+) = 2-hydroxy-3-oxoadipate + CO(2).
50440	2-methylcitrate synthase activity	F	Catalysis of the reaction: H(2)O + oxaloacetate + propanoyl-CoA = (2R,3S)-2-methylcitrate + CoA + H(+).
50441	3-ethylmalate synthase activity	F	Catalysis of the reaction: butanoyl-CoA + glyoxylate + H(2)O = 3-ethylmalate + CoA + H(+).
50442	3-propylmalate synthase activity	F	Catalysis of the reaction: glyoxylate + H(2)O + pentanoyl-CoA = 3-propylmalate + CoA + H(+).
50444	aquacobalamin reductase (NADPH) activity	F	Catalysis of the reaction: 2 cob(II)alamin + NADP+ = 2 aquacob(III)alamin + NADPH + H+.
50445	asparagusate reductase activity	F	Catalysis of the reaction: 3-mercapto-2-mercaptomethylpropanoate + NAD(+) = asparagusate + H(+) + NADH.
50446	azobenzene reductase activity	F	Catalysis of the reaction: N,N-dimethyl-1,4-phenylenediamine + aniline + NADP+ = 4-(dimethylamino)azobenzene + NADPH + H+.
50447	zeatin 9-aminocarboxyethyltransferase activity	F	Catalysis of the reaction: O-acetyl-L-serine + zeatin = L-lupinate + acetate + H(+).
50448	beta-cyclopiazonate dehydrogenase activity	F	Catalysis of the reaction: beta-cyclopiazonate + A = alpha-cyclopiazonate + AH(2).
50449	casbene synthase activity	F	Catalysis of the reaction: all-trans-geranylgeranyl diphosphate = casbene + diphosphate.
50450	citrate (Re)-synthase activity	F	Catalysis of the reaction: acetyl-CoA + H2O + oxaloacetate = citrate + CoA, where the acetyl group is added to the re-face of oxaloacetate; acetyl-CoA provides the two carbon atoms of the pro-R carboxymethyl group.
50451	CoA-disulfide reductase activity	F	Catalysis of the reaction: 2 CoA + NAD+ = CoA-disulfide + NADH + H+.
50452	CoA-glutathione reductase activity	F	Catalysis of the reaction: CoA + glutathione + NADP+ = CoA-glutathione + NADPH + H+.
50453	cob(II)alamin reductase activity	F	Catalysis of the reaction: 2 cob(I)alamin + H(+) + NAD(+) = 2 cob(II)alamin + NADH.
50454	coenzyme F420 hydrogenase activity	F	Catalysis of the reaction: coenzyme F420 + H(2) + H(+) = reduced coenzyme F420.
50455	columbamine oxidase activity	F	Catalysis of the reaction: 2 columbamine + O(2) = 2 berberine + 2 H(2)O.
50456	cystine reductase activity	F	Catalysis of the reaction: 2 L-cysteine + NAD(+) = L-cystine + H(+) + NADH.
50457	decylcitrate synthase activity	F	Catalysis of the reaction: H(2)O + lauroyl-CoA + oxaloacetate = (2S,3S)-2-hydroxytridecane-1,2,3-tricarboxylate + CoA + H(+).
50458	decylhomocitrate synthase activity	F	Catalysis of the reaction: 2-oxoglutarate + H(2)O + lauroyl-CoA = (3S,4S)-3-hydroxytetradecane-1,3,4-tricarboxylate + CoA + H(+).
50459	ethanolamine-phosphate phospho-lyase activity	F	Catalysis of the reaction: H(2)O + phosphoethanolamine = acetaldehyde + NH(4)(+) + phosphate.
50460	hydroxylamine reductase (NADH) activity	F	Catalysis of the reaction: NH3 + NAD+ + H2O = hydroxylamine + NADH + H+.
50461	L-mimosine synthase activity	F	Catalysis of the reaction: 3,4-dihydroxypyridine + O-acetyl-L-serine = 3-(3,4-dihydroxypyridinium-1-yl)-L-alanine + acetate.
50462	N-acetylneuraminate synthase activity	F	Catalysis of the reaction: phosphoenolpyruvate + N-acetyl-D-mannosamine + H2O = phosphate + N-acetylneuraminate.
50463	nitrate reductase [NAD(P)H] activity	F	Catalysis of the reaction: nitrite + NAD(P)+ + H2O = nitrate + NAD(P)H + H+.
50464	nitrate reductase (NADPH) activity	F	Catalysis of the reaction: nitrite + NADP+ + H2O = nitrate + NADPH + H+.
50465	nitroquinoline-N-oxide reductase activity	F	Catalysis of the reaction: 4-(hydroxyamino)quinoline N-oxide + 2 NAD(P)+ + H2O = 4-nitroquinoline N-oxide + 2 NAD(P)H + 2 H+.
50467	pentalenene synthase activity	F	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = diphosphate + pentalenene.
50468	reticuline oxidase activity	F	Catalysis of the reaction: (S)-reticuline + O(2) = (S)-scoulerine + H(2)O(2) + H(+).
50469	sabinene-hydrate synthase activity	F	Catalysis of the reaction: geranyl diphosphate + H(2)O = diphosphate + sabinene hydrate.
50470	trimethylamine dehydrogenase activity	F	Catalysis of the reaction: trimethylamine + H2O + electron-transferring flavoprotein = dimethylamine + formaldehyde + reduced electron-transferring flavoprotein.
50471	uracilylalanine synthase activity	F	Catalysis of the reaction: O3-acetyl-L-serine + uracil = 3-(uracil-1-yl)-L-alanine + acetate.
50472	zeatin reductase activity	F	Catalysis of the reaction: dihydrozeatin + NADP(+) = H(+) + NADPH + zeatin.
50473	arachidonate 15-lipoxygenase activity	F	Catalysis of the reaction: arachidonate + O2 = (5Z,8Z,11Z,13E)-(15S)-15-hydroperoxyicosa-5,8,11,13-tetraenoate.
50474	(S)-norcoclaurine synthase activity	F	Catalysis of the reaction: 4-(2-aminoethyl)benzene-1,2-diol + 4-hydroxyphenylacetaldehyde = (S)-norcoclaurine + H2O.
50476	acetylenedicarboxylate decarboxylase activity	F	Catalysis of the reaction: H2O + acetylenedicarboxylate = CO2 + pyruvate.
50477	acyl-lysine deacylase activity	F	Catalysis of the reaction: H2O + N6-acyl-L-lysine = L-lysine + a carboxylate.
50478	anthranilate 3-monooxygenase activity	F	Catalysis of the reaction: 5,6,7,8-tetrahydrobiopterin + anthranilate + O(2) = 3-hydroxyanthranilate + 7,8-dihydrobiopterin + H(2)O.
50479	glyceryl-ether monooxygenase activity	F	Catalysis of the reaction: 1-alkyl-sn-glycerol + O2 + (tetrahydrobiopterin/tetrahydropteridine) = 1-hydroxyalkyl-sn-glycerol + H2O + (dihydrobiopterin/dihydropteridine).
50480	imidazolonepropionase activity	F	Catalysis of the reaction: (S)-3-(4-oxo-4,5-dihydro-1H-imidazol-5-yl)propanoic acid + H(2)O = N-formimidoyl-L-glutamate + H(+).
50481	mandelate 4-monooxygenase activity	F	Catalysis of the reaction: (S)-mandelate + 5,6,7,8-tetrahydrobiopterin + O(2) = (S)-4-hydroxymandelate + 7,8-dihydrobiopterin + H(2)O. (S)-2-hydroxy-2-phenylacetate is also known as S-mandelate.
50482	arachidonic acid secretion	P	The controlled release of arachidonic acid from a cell or a tissue.
50483	IMP 5'-nucleotidase activity	F	Catalysis of the reaction: 5'-IMP + H2O = inosine + phosphate.
50484	GMP 5'-nucleotidase activity	F	Catalysis of the reaction: 5'-GMP + H2O = guanosine + phosphate.
50485	oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond, with a disulfide as acceptor	F	Catalysis of an oxidation-reduction (redox) reaction in which X-H and Y-H form X-Y and the acceptor is disulfide.
50486	intramolecular transferase activity, transferring hydroxy groups	F	Catalysis of the transfer of a hydroxyl group from one position to another within a single molecule.
50487	sulfoacetaldehyde acetyltransferase activity	F	Catalysis of the reaction: acetyl phosphate + sulfite = phosphate + sulfoacetaldehyde.
50488	ecdysteroid UDP-glucosyltransferase activity	F	Catalysis of the reaction: UDP-glucose + ecdysteroid = UDP + glucosyl-ecdysteroid.
50490	1,4-lactonase activity	F	Catalysis of the reaction: H2O + a 1,4-lactone = a 4-hydroxyacid.
50491	sulcatone reductase activity	F	Catalysis of the reaction: NAD(+) + sulcatol = H(+) + NADH + sulcatone.
50492	glycerol-1-phosphate dehydrogenase [NAD(P)+] activity	F	Catalysis of the reaction: NAD(P)+ + sn-glycerol-1-phosphate = NAD(P)H + H+ + dihydroxy-acetone-phosphate.
50493	GPI anchor biosynthetic process via N-threonyl-glycosylphosphatidylinositolethanolamine	P	The chemical reactions and pathways resulting in the formation of a C-terminal peptidyl-threonyl ethanolamide-linked glycosylphosphatidylinositol (GPI) anchor following hydrolysis of a threonyl-peptide bond in the carboxy-terminal region of a membrane-associated protein.
50494	GSI anchor biosynthetic process via N-glycyl-glycosylsphingolipidinositolethanolamine	P	The chemical reactions and pathways resulting in the formation of a C-terminal peptidyl-glycine ethanolamide-linked glycosylsphingolipidinositol (GSI) anchor following hydrolysis of a glycyl-peptide bond in the carboxy-terminal region of a membrane-associated protein.
50495	peptidyl-glycyl-phosphatidylethanolamine biosynthetic process from peptidyl-glycine	P	The chemical reactions and pathways resulting in the formation of a C-terminal peptidyl-glycine ethanolamide-linked phosphatide following hydrolysis of a glycyl-peptide bond, as in the cleavage of arginine from the carboxy-terminal of Apg8 followed by its amidation with phosphatidylethanolamine.
50496	peptidyl-L-glutamyl 5-omega-hydroxyceramide ester biosynthetic process from peptidyl-glutamine	P	The modification of peptidyl-glutamine residues by deamidation and esterification with omega-hydroxyceramide.
50497	transferase activity, transferring alkylthio groups	F	Catalysis of the transfer of an alkylthio group from one compound (donor) to another (acceptor).
50498	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, with 2-oxoglutarate as one donor, and the other dehydrogenated	F	Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from 2-oxoglutarate and one other donor, and the latter donor is dehydrogenated.
50499	oxidoreductase activity, acting on phosphorus or arsenic in donors, with NAD(P)+ as acceptor	F	Catalysis of an oxidation-reduction (redox) reaction in which a phosphorus- or arsenic-containing group acts as a hydrogen or electron donor and reduces a NAD(P)+ to NAD(P)H.
50500	1,3-beta-galactosyl-N-acetylhexosamine phosphorylase activity	F	Catalysis of the reaction: phosphate + beta-D-galactopyranosyl-(1->3)-N-acetyl-D-glucosamine = N-acetyl-D-glucosamine + alpha-D-galactopyranose 1-phosphate.
50501	hyaluronan synthase activity	F	Catalysis of the reaction: UDP-D-glucuronate + UDP-N-acetyl-D-glucosamine = [beta-N-acetyl-D-glucosaminyl-(1->4)-beta-D-glucuronosyl-(1->3)](n) + 2n UDP.
50502	cis-zeatin O-beta-D-glucosyltransferase activity	F	Catalysis of the reaction: cis-zeatin + UDP-D-glucose = O-beta-D-glucosyl-cis-zeatin + H(+) + UDP.
50503	trehalose 6-phosphate phosphorylase activity	F	Catalysis of the reaction: trehalose 6-phosphate + phosphate = glucose 6-phosphate + beta-D-glucose 1-phosphate.
50504	mannosyl-3-phosphoglycerate synthase activity	F	Catalysis of the reaction: 3-phospho-D-glycerate + GDP-alpha-D-mannose = 2-(alpha-D-mannosyl)-3-phosphoglycerate + GDP + H(+).
50505	hydroquinone glucosyltransferase activity	F	Catalysis of the reaction: hydroquinone + UDP-D-glucose = H(+) + hydroquinone O-beta-D-glucopyranoside + UDP.
50506	vomilenine glucosyltransferase activity	F	Catalysis of the reaction: UDP-D-glucose + vomilenine = H(+) + raucaffricine + UDP.
50507	indoxyl-UDPG glucosyltransferase activity	F	Catalysis of the reaction: indoxyl + UDP-D-glucose = H(+) + indican + UDP.
50508	glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity	F	Catalysis of the reaction: beta-D-glucuronosyl-(1,4)-N-acetyl-alpha-D-glucosaminyl-proteoglycan + UDP-N-acetyl-D-glucosamine = N-acetyl-alpha-D-glucosaminyl-(1,4)-beta-D-glucuronosyl-(1,4)-N-acetyl-alpha-D-glucosaminyl-proteoglycan + UDP.
50509	N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity	F	Catalysis of the reaction: N-acetyl-alpha-D-glucosaminyl-(1,4)-beta-D-glucuronosyl-proteoglycan + UDP-alpha-D-glucuronate = beta-D-glucuronosyl-(1,4)-N-acetyl-alpha-D-glucosaminyl-(1,4)-beta-D-glucuronosyl-proteoglycan + UDP.
50510	N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity	F	Catalysis of the reaction: N-acetyl-beta-D-galactosaminyl-(1,4)-beta-D-glucuronosyl-proteoglycan + UDP-alpha-D-glucuronate = beta-D-glucuronosyl-(1,3)-N-acetyl-beta-D-galactosaminyl-(1,4)-beta-D-glucuronosyl-proteoglycan + UDP.
50511	undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase activity	F	Catalysis of the reaction: Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol + UDP-N-acetyl-D-glucosamine = GlcNAc-(1,4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol + UDP.
50512	lactosylceramide 4-alpha-galactosyltransferase activity	F	Catalysis of the reaction: beta-D-galactosyl-(1,4)-D-glucosylceramide + UDP-galactose = alpha-D-galactosyl-(1,4)-beta-D-galactosyl-(1,4)-D-glucosylceramide + UDP.
50513	glycoprotein 2-beta-D-xylosyltransferase activity	F	Catalysis of the reaction: N(4)-{N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->6)]-beta-D-mannosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-N-acetyl-beta-D-glucosaminyl}-L-asparagine + UDP-alpha-D-xylose = N(4)-{N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->3)-[N-acetyl-beta-D-glucosaminyl-(1->2)-alpha-D-mannosyl-(1->6)]-[beta-D-xylosyl-(1->2)]-beta-D-mannosyl-(1->4)-N-acetyl-beta-D-glucosaminyl-(1->4)-N-acetyl-beta-D-glucosaminyl}-L-asparagine + H(+) + UDP.
50514	homospermidine synthase (spermidine-specific) activity	F	Catalysis of the reaction: spermidine + putrescine = sym-homospermidine + propane-1,3-diamine.
50515	4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase activity	F	Catalysis of the reaction: 4-CDP-2-C-methyl-D-erythritol + ATP = 4-CDP-2-C-methyl-D-erythritol 2-phosphate + ADP + 2 H(+).
50518	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity	F	Catalysis of the reaction: 2-C-methyl-D-erythritol 4-phosphate + CTP = 4-CDP-2-C-methyl-D-erythritol + diphosphate.
50519	holo-citrate lyase synthase activity	F	Catalysis of the reaction: apo-citrate lyase + 2'-(5''-triphosphoribosyl)-3'-dephospho-CoA = diphosphate + holo-citrate lyase.
50520	phosphatidylcholine synthase activity	F	Catalysis of the reaction: CDP-diacylglycerol + choline = 1,2-diacyl-sn-glycero-3-phosphocholine + CMP + H(+).
50521	alpha-glucan, water dikinase activity	F	Catalysis of the reaction: ATP + alpha-glucan + H2O = AMP + phospho-alpha-glucan + phosphate.
50522	oxidoreductase activity, acting on phosphorus or arsenic in donors, with other known acceptors	F	Catalysis of an oxidation-reduction (redox) reaction in which phosphorus or arsenic acts as a hydrogen or electron donor and reduces a known acceptor other than disulfide, NAD or NADP.
50524	coenzyme-B sulfoethylthiotransferase activity	F	Catalysis of the reaction: coenzyme B + methyl-coenzyme M = coenzyme M-coenzyme B heterodisulfide + methane. Methyl-CoM is also known as 2-(methylthio)ethanesulfonate, coenzyme B as N-(7-mercaptoheptanoyl)threonine 3-O-phosphate, and coenzyme M-coenzyme B heterodisulfide as CoM-S-S-CoB.
50525	cutinase activity	F	Catalysis of the reaction: cutin + H2O = cutin monomers.
50526	poly(3-hydroxybutyrate) depolymerase activity	F	Catalysis of the reaction: H2O + poly[(R)-3-hydroxybutanoate](n) = poly[(R)-3-hydroxybutanoate](x) + poly[(R)-3-hydroxybutanoate](n-x); x is 1-5.
50527	poly(3-hydroxyoctanoate) depolymerase activity	F	Catalysis of the reaction: H2O + poly[(R)-3-hydroxyoctanoate](n) = poly[(R)-3-hydroxyoctanoate](x) + poly[(R)-3-hydroxyoctanoate](n-x); x is 1-5.
50528	acyloxyacyl hydrolase activity	F	Catalysis of the reaction: 3-(acyloxy)acyl group of bacterial toxin = 3-hydroxyacyl group of bacterial toxin + a fatty acid.
50529	polyneuridine-aldehyde esterase activity	F	Catalysis of the reaction: H(2)O + polyneuridine aldehyde = 16-epivellosimine + CO(2) + methanol.
50530	glucosylglycerol 3-phosphatase activity	F	Catalysis of the reaction: 2-O-(beta-D-glucosyl)-sn-glycerol 3-phosphate + H(2)O = 2-O-(beta-D-glucosyl)-sn-glycerol + phosphate.
50531	mannosyl-3-phosphoglycerate phosphatase activity	F	Catalysis of the reaction: 2-(alpha-D-mannosyl)-3-phosphoglycerate + H(2)O = 2-(alpha-D-mannosyl)-D-glycerate + phosphate.
50532	2-phosphosulfolactate phosphatase activity	F	Catalysis of the reaction: (2R)-O-phospho-3-sulfolactate + H(2)O = (R)-3-sulfolactate + phosphate.
50533	5-phytase activity	F	Catalysis of the reaction: H2O + myo-inositol hexakisphosphate = phosphate + 1L-myo-inositol 1,2,3,4,6-pentakisphosphate.
50534	3-deoxyoctulosonase activity	F	Catalysis of the reaction: 3-deoxyoctulosonyl-lipopolysaccharide + H2O = 3-deoxyoctulosonic acid + lipopolysaccharide.
50535	beta-primeverosidase activity	F	Catalysis of the reaction: a 6-O-(beta-D-xylopyranosyl)-beta-D-glucopyranoside + H2O = 6-O-(beta-D-xylopyranosyl)-beta-D-glucopyranose + an alcohol.
50536	(S)-N-acetyl-1-phenylethylamine hydrolase activity	F	Catalysis of the reaction: N-acetylphenylethylamine + H(2)O = acetate + phenylethylamine.
50537	mandelamide amidase activity	F	Catalysis of the reaction: (R)-mandelamide + H(2)O = (R)-mandelate + NH(4)(+).
50538	N-carbamoyl-L-amino-acid hydrolase activity	F	Catalysis of the reaction: N-carbamoyl-L-2-amino acid + H2O = L-2-amino acid + NH3 + CO2. The N-carbamoyl-L-2-amino acid is a 2-ureido carboxylate.
50539	maleimide hydrolase activity	F	Catalysis of the reaction: H(2)O + maleimide = H(+) + maleamate.
50540	2-aminomuconate deaminase activity	F	Catalysis of the reaction: 2-aminomuconate + H(2)O + H(+) = (Z)-5-oxohex-2-enedioate + NH(4)(+).
50541	beta,beta-carotene-9',10'-dioxygenase activity	F	Catalysis of the reaction: beta-carotene + O2 = beta-apo-10'-carotenal + beta-ionone.
50542	icosanoid binding	F	Interacting selectively and non-covalently with icosanoids, any C20 polyunsaturated fatty acids or their derivatives, including the leukotrienes and the prostanoids.
50543	icosatetraenoic acid binding	F	Interacting selectively and non-covalently with icosatetraenoic acid, any straight-chain fatty acid with twenty carbon atoms and four double bonds per molecule.
50544	arachidonic acid binding	F	Interacting selectively and non-covalently with arachidonic acid, a straight chain fatty acid with 20 carbon atoms and four double bonds per molecule. Arachidonic acid is the all-Z-(5,8,11,14)-isomer.
50545	sulfopyruvate decarboxylase activity	F	Catalysis of the reaction: 3-sulfopyruvate + H(+) = CO(2) + sulfoacetaldehyde.
50546	4-hydroxyphenylpyruvate decarboxylase activity	F	Catalysis of the reaction: (4-hydroxyphenyl)pyruvate + H(+) = (4-hydroxyphenyl)acetaldehyde + CO(2).
50547	vanillin synthase activity	F	Catalysis of the reaction: 3-hydroxy-3-(4-hydroxy-3-methoxyphenyl)propanoyl-CoA = acetyl-CoA + vanillin.
50548	trans-feruloyl-CoA hydratase activity	F	Catalysis of the reaction: trans-feruloyl-CoA + H2O = 4-hydroxy-3-methoxyphenyl-beta-hydroxypropionyl-CoA.
50549	cyclohexyl-isocyanide hydratase activity	F	Catalysis of the reaction: N-cyclohexylformamide + H(+) = cyclohexyl isocyanide + H(2)O.
50550	pinene synthase activity	F	Catalysis of the reaction: geranyl diphosphate = pinene + diphosphate.
50551	myrcene synthase activity	F	Catalysis of the reaction: geranyl diphosphate = diphosphate + myrcene.
50552	(4S)-limonene synthase activity	F	Catalysis of the reaction: geranyl diphosphate = (4S)-limonene + diphosphate.
50553	taxadiene synthase activity	F	Catalysis of the reaction: all-trans-geranylgeranyl diphosphate = diphosphate + taxa-4,11-diene.
50554	abietadiene synthase activity	F	Catalysis of the reaction: (+)-copalyl diphosphate = (-)-abietadiene + diphosphate.
50555	2-hydroxypropyl-CoM lyase activity	F	Catalysis of the reactions: (R)-2-hydroxypropyl-CoM = H-S-CoM + (R)-1,2-epoxypropane, and (S)-2-hydroxypropyl-CoM = H-S-CoM + (S)-1,2-epoxypropane.
50556	deacetylisoipecoside synthase activity	F	Catalysis of the reaction: deacetylisoipecoside + H(2)O = dopamine + secologanin.
50557	deacetylipecoside synthase activity	F	Catalysis of the reaction: deacetylipecoside + H(2)O = dopamine + secologanin.
50558	maltose epimerase activity	F	Catalysis of the reaction: alpha-maltose = beta-maltose.
50559	copalyl diphosphate synthase activity	F	Catalysis of the reaction: all-trans-geranylgeranyl diphosphate = (+)-copalyl diphosphate.
50560	aspartate-tRNA(Asn) ligase activity	F	Catalysis of the reaction: tRNA(Asx) + L-aspartate + ATP = aspartyl-tRNA(Asx) + diphosphate + AMP.
50561	glutamate-tRNA(Gln) ligase activity	F	Catalysis of the reaction: tRNA(Glx) + L-glutamate + ATP = glutamyl-tRNA(Glx) + diphosphate + AMP.
50562	lysine-tRNA(Pyl) ligase activity	F	Catalysis of the reaction: tRNA(Pyl) + L-lysine + ATP = L-lysyl-tRNA(Pyl) + diphosphate + AMP.
50563	trans-feruloyl-CoA synthase activity	F	Catalysis of the reaction: ferulic acid + CoASH + ATP = trans-feruloyl-CoA + products of ATP breakdown.
50564	N-(5-amino-5-carboxypentanoyl)-L-cysteinyl-D-valine synthase activity	F	Catalysis of the reaction: L-2-aminoadipate + L-cysteine + L-valine + 3 ATP + H(2)O = N-[(5S)-5-amino-5-carboxypentanoyl]-L-cysteinyl-D-valine + 3 AMP + 3 diphosphate + 6 H(+).
50565	aerobactin synthase activity	F	Catalysis of the reaction: 2 N(6)-acetyl-N(6)-hydroxy-L-lysine + 4 ATP + citrate + 2 H(2)O = 4 ADP + aerobactin + 8 H(+) + 4 phosphate.
50566	asparaginyl-tRNA synthase (glutamine-hydrolyzing) activity	F	Catalysis of the reaction: L-glutamine + aspartyl-tRNA(Asn) + ATP = L-glutamate + asparaginyl-tRNA(Asn) + phosphate + ADP.
50567	glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity	F	Catalysis of the reaction: L-glutamine + glutamyl-tRNA(Gln) + ATP = L-glutamate + glutaminyl-tRNA(Gln) + phosphate + ADP.
50568	protein-glutamine glutaminase activity	F	Catalysis of the reaction: protein L-glutamine + H2O = protein L-glutamate + NH3.
50569	glycolaldehyde dehydrogenase activity	F	Catalysis of the reaction: glycolaldehyde + H(2)O + NAD(+) = glycolate + 2 H(+) + NADH.
50570	4-hydroxythreonine-4-phosphate dehydrogenase activity	F	Catalysis of the reaction: 4-(phosphonooxy)-threonine + NAD+ = 2-amino-3-oxo-4-phosphonooxybutyrate + NADH + H+.
50571	1,5-anhydro-D-fructose reductase activity	F	Catalysis of the reaction: 1,5-anhydro-D-glucitol + NADP(+) = 1,5-anhydro-D-fructose + H(+) + NADPH.
50572	L-idonate 5-dehydrogenase activity	F	Catalysis of the reaction: L-idonate + NAD(P)+ = 5-dehydrogluconate + NAD(P)H + H+.
50573	dTDP-4-dehydro-6-deoxyglucose reductase activity	F	Catalysis of the reaction: dTDP-D-fucose + NADP(+) = dTDP-4-dehydro-6-deoxy-alpha-D-glucose + H(+) + NADPH.
50574	2-(R)-hydroxypropyl-CoM dehydrogenase activity	F	Catalysis of the reaction: 2-(R)-hydroxypropyl-coenzyme M + NAD(+) = 2-oxopropyl-coenzyme M + H(+) + NADH.
50575	2-(S)-hydroxypropyl-CoM dehydrogenase activity	F	Catalysis of the reaction: 2-(S)-hydroxypropyl-coenzyme M + NAD(+) = 2-oxopropyl-coenzyme M + H(+) + NADH.
50577	GDP-L-fucose synthase activity	F	Catalysis of the reaction: GDP-L-fucose + NAD+ = GDP-4-dehydro-6-deoxy-D-mannose + NADH + H+.
50578	(R)-2-hydroxyacid dehydrogenase activity	F	Catalysis of the reaction: (S)-3-sulfolactate + NAD(P)+ = 3-sulfopyruvate + NAD(P)H + H+.
50579	vellosimine dehydrogenase activity	F	Catalysis of the reaction: 10-deoxysarpagine + NADP(+) = H(+) + NADPH + vellosimine.
50580	2,5-didehydrogluconate reductase activity	F	Catalysis of the reaction: 2-dehydro-D-gluconate + NADP+ = 2,5-didehydro-D-gluconate + NADPH + H+.
50581	D-mannitol oxidase activity	F	Catalysis of the reaction: mannitol + O2 = mannose + H2O2.
50582	xylitol oxidase activity	F	Catalysis of the reaction: xylitol + O2 = xylose + H2O2.
50583	hydrogen dehydrogenase (NADP+) activity	F	Catalysis of the reaction: NADP+ + H2 = NADPH + H+.
50584	linoleate 11-lipoxygenase activity	F	Catalysis of the reaction: linoleate + O(2) = (9Z,11S,12Z)-11-hydroperoxyoctadeca-9,12-dienoate.
50585	4-hydroxymandelate synthase activity	F	Catalysis of the reaction: 4-hydroxyphenylpyruvate + O2 = 4-hydroxymandelate + CO2.
50586	3-hydroxy-2-methylquinolin-4-one 2,4-dioxygenase activity	F	Catalysis of the reaction: 3-hydroxy-2-methylquinolin-4(1H)-one + H(+) + O(2) = N-acetylanthranilate + CO.
50587	chlorite O2-lyase activity	F	Catalysis of the reaction: chloride + O(2) = chlorite.
50588	apo-beta-carotenoid-14',13'-dioxygenase activity	F	Catalysis of the reaction: 8'-apo-beta-carotenol + O(2) = (E,E)-7-hydroxy-6-methylhepta-3,5-dienal + 14'-apo-beta-carotenal.
50589	leucocyanidin oxygenase activity	F	Catalysis of the reaction: leucocyanidin + 2-oxoglutarate + O2 = cis- or trans-dihydroquercetin + succinate + CO2 + 2 H2O.
50590	desacetoxyvindoline 4-hydroxylase activity	F	Catalysis of the reaction: desacetoxyvindoline + 2-oxoglutarate + O2 = desacetylvindoline + succinate + CO2.
50591	quinine 3-monooxygenase activity	F	Catalysis of the reaction: H(+) + NADPH + O(2) + quinine = 3-hydroxyquinine + H(2)O + NADP(+).
50592	4-hydroxyphenylacetaldehyde oxime monooxygenase activity	F	Catalysis of the reaction: (Z)-(4-hydroxyphenyl)acetaldehyde oxime + H(+) + NADPH + O(2) = (S)-4-hydroxymandelonitrile + 2 H(2)O + NADP(+).
50593	N-methylcoclaurine 3'-monooxygenase activity	F	Catalysis of the reaction: (S)-N-methylcoclaurine + H(+) + NADPH + O(2) = (S)-3'-hydroxy-N-methylcoclaurine + H(2)O + NADP(+).
50594	tabersonine 16-hydroxylase activity	F	Catalysis of the reaction: H(+) + NADPH + O(2) + tabersonine = 16-hydroxytabersonine + H(2)O + NADP(+).
50595	7-deoxyloganin 7-hydroxylase activity	F	Catalysis of the reaction: 7-deoxyloganin + NADPH + H+ + O2 = loganin + NADP+ + H2O.
50596	vinorine hydroxylase activity	F	Catalysis of the reaction: H(+) + NADPH + O(2) + vinorine = H(2)O + NADP(+) + vomilenine.
50597	taxane 10-beta-hydroxylase activity	F	Catalysis of the reaction: H(+) + NADPH + O(2) + taxa-4(20),11-dien-5alpha-yl acetate = 10beta-hydroxytaxa-4(20),11-dien-5alpha-yl acetate + H(2)O + NADP(+).
50598	taxane 13-alpha-hydroxylase activity	F	Catalysis of the reaction: H(+) + NADPH + O(2) + taxa-4(20),11-dien-5alpha-ol = H(2)O + NADP(+) + taxa-4(20),11-dien-5alpha,13alpha-diol.
50599	deacetoxycephalosporin-C synthase activity	F	Catalysis of the reaction: 2-oxoglutarate + O(2) + penicillin N = CO(2) + deacetoxycephalosporin C + H(2)O + succinate.
50600	myristoyl-CoA 11-(E) desaturase activity	F	Catalysis of the reaction: myristoyl-CoA + NAD(P)H + H+ + O2 = (E)-11-tetradecenoyl-CoA + NAD(P)+ + 2 H2O.
50601	myristoyl-CoA 11-(Z) desaturase activity	F	Catalysis of the reaction: myristoyl-CoA + NAD(P)H + H+ + O2 = (Z)-11-tetradecenoyl-CoA + NAD(P)+ + 2 H2O.
50602	monoprenyl isoflavone epoxidase activity	F	Catalysis of the reaction: O2 + NADPH + H+ + 7-O-methylluteone = H2O + NADP+ + dihydrofurano derivatives.
50603	thiophene-2-carbonyl-CoA monooxygenase activity	F	Catalysis of the reaction: AH(2) + O(2) + thiophene-2-carbonyl-CoA = 5-hydroxythiophene-2-carbonyl-CoA + A + H(2)O + H(+).
50604	taxadiene 5-alpha-hydroxylase activity	F	Catalysis of the reaction: AH(2) + O(2) + taxa-4,11-diene = A + H(2)O + taxa-4(20),11-dien-5alpha-ol.
50605	superoxide reductase activity	F	Catalysis of the reaction: superoxide + reduced rubredoxin + 2 H+ = H2O2 + rubredoxin.
50606	4-carboxy-2-hydroxymuconate semialdehyde hemiacetal dehydrogenase activity	F	Catalysis of the reaction: 4-carboxy-2-hydroxymuconate semialdehyde hemiacetal + NADP(+) = 2-oxo-2H-pyran-4,6-dicarboxylate + H(+) + NADPH.
50607	mycothiol-dependent formaldehyde dehydrogenase activity	F	Catalysis of the reaction: formaldehyde + mycothiol + NAD+ = S-formylmycothiol + NADH + H+.
50608	vanillin dehydrogenase activity	F	Catalysis of the reaction: H(2)O + NAD(+) + vanillin = 2 H(+) + NADH + vanillate.
50609	phosphonate dehydrogenase activity	F	Catalysis of the reaction: H(2)O + NAD(+) + phosphonate = 2 H(+) + NADH + phosphate.
50610	methylarsonate reductase activity	F	Catalysis of the reaction: 2 glutathione + H(+) + methylarsonate = glutathione disulfide + H(2)O + methylarsonous acid.
50611	arsenate reductase (azurin) activity	F	Catalysis of the reaction: H(2)O + arsenite + 2 oxidized azurin = 2 H(+) + 2 reduced azurin + arsenate.
50612	arsenate reductase (donor) activity	F	Catalysis of the reaction: A + arsenite + H(2)O = AH(2) + arsenate + 2 H(+).
50613	delta14-sterol reductase activity	F	Catalysis of the reaction: NADP+ + 4,4-dimethyl-5-alpha-cholesta-8,24-dien-3-beta-ol = NADPH + H+ + 4,4-dimethyl-5-alpha-cholesta-8,14,24-trien-3-beta-ol.
50614	delta24-sterol reductase activity	F	Catalysis of the reaction: NADP+ + 5-alpha-cholest-7-en-3-beta-ol = NADPH + H+ + 5-alpha-cholesta-7,24-dien-3-beta-ol.
50615	1,2-dihydrovomilenine reductase activity	F	Catalysis of the reaction: 17-O-acetylnorajmaline + NADP(+) = 1,2-dihydrovomilenine + H(+) + NADPH.
50616	secologanin synthase activity	F	Catalysis of the reaction: loganin + NADPH + H+ + O2 = secologanin + NADP+ + 2 H2O.
50617	15,16-dihydrobiliverdin:ferredoxin oxidoreductase activity	F	Catalysis of the reaction: 15,16-dihydrobiliverdin + oxidized ferredoxin = biliverdin IXa + reduced ferredoxin.
50618	phycoerythrobilin:ferredoxin oxidoreductase activity	F	Catalysis of the reaction: (3Z)-phycoerythrobilin + oxidized ferredoxin = 15,16-dihydrobiliverdin + reduced ferredoxin.
50619	phytochromobilin:ferredoxin oxidoreductase activity	F	Catalysis of the reaction: (3Z)-phytochromobilin + oxidized ferredoxin = biliverdin IXa + reduced ferredoxin.
50620	phycocyanobilin:ferredoxin oxidoreductase activity	F	Catalysis of the reaction: (3Z)-phycocyanobilin + oxidized ferredoxin = biliverdin IXa + reduced ferredoxin.
50621	tryptophan alpha,beta-oxidase activity	F	Catalysis of the reaction: L-tryptophan + O(2) = alpha,beta-didehydrotryptophan + H(2)O(2) + H(+).
50622	glycine dehydrogenase (cyanide-forming) activity	F	Catalysis of the reaction: glycine + 2 A = HCN + CO2 + 2 AH2.
50623	berberine reductase activity	F	Catalysis of the reaction: (R)-canadine + 2 NADP(+) = berberine + H(+) + 2 NADPH.
50624	vomilenine reductase activity	F	Catalysis of the reaction: 1,2-dihydrovomilenine + NADP(+) = H(+) + NADPH + vomilenine.
50625	2-hydroxy-1,4-benzoquinone reductase activity	F	Catalysis of the reaction: 2-hydroxy-1,4-benzoquinone + 2 H(+) + NADH = benzene-1,2,4-triol + NAD(+).
50626	trimethylamine-N-oxide reductase (cytochrome c) activity	F	Catalysis of the reaction: trimethylamine + 2 (ferricytochrome c)-subunit + H2O = trimethylamine-N-oxide + 2 (ferrocytochrome c)-subunit + 2 H+.
50627	mycothione reductase activity	F	Catalysis of the reaction: NAD(P)+ + mycothiol = NAD(P)H + H+ + mycothione.
50628	2-oxopropyl-CoM reductase (carboxylating) activity	F	Catalysis of the reaction: acetoacetate + coenzyme M + NADP(+) = 2-oxopropyl-coenzyme M + CO(2) + NADPH.
50629	tetrachloroethene reductive dehalogenase activity	F	Catalysis of the reaction: trichloroethene + chloride + acceptor = tetrachloroethene + reduced acceptor.
50630	(iso)eugenol O-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + isoeugenol = S-adenosyl-L-homocysteine + isomethyleugenol.
50631	corydaline synthase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + 2 NADPH + palmatine = S-adenosyl-L-homocysteine + corydaline + 2 NADP(+).
50632	propionyl-CoA C2-trimethyltridecanoyltransferase activity	F	Catalysis of the reaction: 4,8,12-trimethyltridecanoyl-CoA + propanoyl-CoA = 3-oxopristanoyl-CoA + CoA.
50633	acetyl-CoA C-myristoyltransferase activity	F	Catalysis of the reaction: myristoyl-CoA + acetyl-CoA = 3-oxopalmitoyl-CoA + CoA.
50634	phloroisovalerophenone synthase activity	F	Catalysis of the reaction: isovaleryl-CoA + 3 malonyl-CoA = 4 CoASH + 3 CO2 + 3-methyl-1-(2,4,6-trihydroxyphenyl)butan-1-one.
50635	acridone synthase activity	F	Catalysis of the reaction: N-methylanthranilyl-CoA + 3 H(+) + 3 malonyl-CoA = 1,3-dihydroxy-N-methylacridone + 3 CO(2) + 4 CoA + H(2)O.
50636	vinorine synthase activity	F	Catalysis of the reaction: 16-epivellosimine + acetyl-CoA = CoA + vinorine.
50637	lovastatin nonaketide synthase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine(1+) + acetyl-CoA + 18 H(+) + 8 malonyl-CoA + 11 NADPH = S-adenosyl-L-homocysteine + 8 CO(2) + 9 CoA + dihydromonacolin L + 6 H(2)O + 11 NADP(+).
50638	taxadien-5-alpha-ol O-acetyltransferase activity	F	Catalysis of the reaction: acetyl-CoA + taxa-4(20),11-dien-5alpha-ol = CoA + taxa-4(20),11-dien-5alpha-yl acetate.
50639	10-hydroxytaxane O-acetyltransferase activity	F	Catalysis of the reaction: 10-desacetyltaxuyunnanin C + acetyl-CoA = CoA + taxuyunnanin C.
50640	isopenicillin-N N-acyltransferase activity	F	Catalysis of the reaction: phenylacetyl-CoA + isopenicillin N + H2O = CoA + penicillin G + L-2-aminohexanedioate.
50641	6-methylsalicylic acid synthase activity	F	Catalysis of the reaction: acetyl-CoA + 3 H(+) + 3 malonyl-CoA + NADPH = 6-methylsalicylate + 3 CO(2) + 4 CoA + H(2)O + NADP(+).
50642	2-alpha-hydroxytaxane 2-O-benzoyltransferase activity	F	Catalysis of the reaction: 10-deacetyl-2-debenzoylbaccatin III + benzoyl-CoA = 10-deacetylbaccatin III + CoA.
50643	10-deacetylbaccatin III 10-O-acetyltransferase activity	F	Catalysis of the reaction: 10-deacetylbaccatin III + acetyl-CoA = baccatin III + CoA.
50644	cis-p-coumarate glucosyltransferase activity	F	Catalysis of the reaction: cis-4-coumarate + UDP-D-glucose = 4'-O-beta-D-glucosyl-cis-4-coumarate + H(+) + UDP.
50645	limonoid glucosyltransferase activity	F	Catalysis of the reaction: UDP-glucose + limonin = glucosyl-limonin + UDP.
50646	5-oxo-6E,8Z,11Z,14Z-icosatetraenoic acid binding	F	Interacting selectively and non-covalently with 5-oxo-6E,8Z,11Z,14Z-icosatetraenoic acid, a straight-chain fatty acid with twenty carbon atoms and four double bonds.
50647	5-hydroxy-6E,8Z,11Z,14Z-icosatetraenoic acid binding	F	Interacting selectively and non-covalently with 5-hydroxy-6E,8Z,11Z,14Z-icosatetraenoic acid, a straight-chain fatty acid with twenty carbon atoms and four double bonds.
50648	5(S)-hydroxyperoxy-6E,8Z,11Z,14Z-icosatetraenoic acid binding	F	Interacting selectively and non-covalently with 5(S)-hydroxyperoxy-6E,8Z,11Z,14Z-icosatetraenoic acid, a straight-chain fatty acid with twenty carbon atoms and four double bonds.
50649	testosterone 6-beta-hydroxylase activity	F	Catalysis of the reaction: testosterone + donor-H2 + O2 = 6-beta-hydroxytestosterone + H2O.
50650	chondroitin sulfate proteoglycan biosynthetic process	P	The chemical reactions and pathways resulting in the formation of chondroitin sulfate proteoglycan, any glycoprotein whose glycosaminoglycan units are chondroitin sulfate. Chondroitin sulfates are a group of 10-60 kDa glycosaminoglycans, widely distributed in cartilage and other mammalian connective tissues; the repeat units consist of beta-(1,4)-linked D-glucuronyl beta-(1,3)-N-acetyl-D-galactosamine sulfate.
50651	dermatan sulfate proteoglycan biosynthetic process	P	The chemical reactions and pathways resulting in the formation of dermatan sulfate proteoglycan, any glycoprotein whose glycosaminoglycan units are dermatan sulfate (chondroitin sulfate B). Dermatan sulfate is a glycosaminoglycan with repeats consisting of beta-(1,4)-linked L-iduronyl-beta-(1,3)-N-acetyl-D-galactosamine 4-sulfate units.
50652	dermatan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process	P	The elongation of dermatan sulfate proteoglycan chains by alternate addition of N-acetylhexosamine and GlcUA residues to the GAG-protein linkage region tetrasaccharide of dermatan sulfate.
50653	chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process	P	The elongation of chondroitin sulfate proteoglycan chains by alternate addition of N-acetylhexosamine and GlcUA residues to the GAG-protein linkage region tetrasaccharide of chondroitin sulfate.
50654	chondroitin sulfate proteoglycan metabolic process	P	The chemical reactions and pathways involving chondroitin sulfate proteoglycan, any glycoprotein whose glycosaminoglycan units are chondroitin sulfate. Chondroitin sulfates are a group of 10-60 kDa glycosaminoglycans, widely distributed in cartilage and other mammalian connective tissues; the repeat units consist of beta-(1,4)-linked D-glucuronyl beta-(1,3)-N-acetyl-D-galactosamine sulfate.
50655	dermatan sulfate proteoglycan metabolic process	P	The chemical reactions and pathways involving dermatan sulfate proteoglycan, any glycoprotein whose glycosaminoglycan units are dermatan sulfate (chondroitin sulfate B). Dermatan sulfate is a glycosaminoglycan with repeats consisting of beta-(1,4)-linked L-iduronyl-beta-(1,3)-N-acetyl-D-galactosamine 4-sulfate units.
50656	3'-phosphoadenosine 5'-phosphosulfate binding	F	Interacting selectively and non-covalently with 3'-phosphoadenosine 5'-phosphosulfate (PAPS), a naturally occurring mixed anhydride. It is an intermediate in the formation of a variety of sulfo compounds in biological systems.
50657	nucleic acid transport	P	The directed movement of nucleic acids, single or double-stranded polynucleotides involved in the storage, transmission and transfer of genetic information, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
50658	RNA transport	P	The directed movement of RNA, ribonucleic acids, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
50659	N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity	F	Catalysis of the reactions: 3'-phosphoadenylyl sulfate + dermatan = adenosine 3',5'-bisphosphate + dermatan 6'-sulfate and 3'-phosphoadenylyl sulfate + chondroitin = adenosine 3',5'-bisphosphate + chondroitin 6'-sulfate.
50660	flavin adenine dinucleotide binding	F	Interacting selectively and non-covalently with FAD, flavin-adenine dinucleotide, the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes, in either the oxidized form, FAD, or the reduced form, FADH2.
50661	NADP binding	F	Interacting selectively and non-covalently with nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions; binding may be to either the oxidized form, NADP+, or the reduced form, NADPH.
50662	coenzyme binding	F	Interacting selectively and non-covalently with a coenzyme, any of various nonprotein organic cofactors that are required, in addition to an enzyme and a substrate, for an enzymatic reaction to proceed.
50663	cytokine secretion	P	The regulated release of cytokines from a cell. Cytokines are any of a group of proteins that function to control the survival, growth and differentiation of tissues and cells, and which have autocrine and paracrine activity.
50664	oxidoreductase activity, acting on NAD(P)H, oxygen as acceptor	F	Catalysis of an oxidation-reduction (redox) reaction in which NADH or NADPH acts as a hydrogen or electron donor and reduces an oxygen molecule.
50665	hydrogen peroxide biosynthetic process	P	The chemical reactions and pathways resulting in the formation of hydrogen peroxide (H2O2), a potentially harmful byproduct of aerobic cellular respiration which can cause damage to DNA.
50666	regulation of homocysteine metabolic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving homocysteine, the amino acid alpha-amino-gamma-mercaptobutanoic acid.
50667	homocysteine metabolic process	P	The chemical reactions and pathways involving homocysteine, the amino acid alpha-amino-gamma-mercaptobutanoic acid. Homocysteine is an important intermediate in the metabolic reactions of its S-methyl derivative, methionine.
50668	positive regulation of homocysteine metabolic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving homocysteine.
50669	negative regulation of homocysteine metabolic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving homocysteine.
50670	regulation of lymphocyte proliferation	P	Any process that modulates the frequency, rate or extent of lymphocyte proliferation.
50671	positive regulation of lymphocyte proliferation	P	Any process that activates or increases the rate or extent of lymphocyte proliferation.
50672	negative regulation of lymphocyte proliferation	P	Any process that stops, prevents or reduces the rate or extent of lymphocyte proliferation.
50673	epithelial cell proliferation	P	The multiplication or reproduction of epithelial cells, resulting in the expansion of a cell population. Epithelial cells make up the epithelium, the covering of internal and external surfaces of the body, including the lining of vessels and other small cavities. It consists of cells joined by small amounts of cementing substances.
50674	urothelial cell proliferation	P	The multiplication or reproduction of urothelial cells, resulting in the expansion of a cell population. Urothelial cells make up a layer of transitional epithelium in the wall of the bladder, ureter, and renal pelvis, external to the lamina propria.
50675	regulation of urothelial cell proliferation	P	Any process that modulates the frequency, rate or extent of urothelial cell proliferation.
50676	negative regulation of urothelial cell proliferation	P	Any process that stops, prevents or reduces the rate or extent of urothelial cell proliferation.
50677	positive regulation of urothelial cell proliferation	P	Any process that activates or increases the rate or extent of urothelial cell proliferation.
50678	regulation of epithelial cell proliferation	P	Any process that modulates the frequency, rate or extent of epithelial cell proliferation.
50679	positive regulation of epithelial cell proliferation	P	Any process that activates or increases the rate or extent of epithelial cell proliferation.
50680	negative regulation of epithelial cell proliferation	P	Any process that stops, prevents or reduces the rate or extent of epithelial cell proliferation.
50681	androgen receptor binding	F	Interacting selectively and non-covalently with an androgen receptor.
50682	AF-2 domain binding	F	Interacting selectively and non-covalently with the AF-2 domain of a protein, a highly conserved ligand-dependent transactivation domain which is essential for receptor-mediated transcriptional activation.
50683	AF-1 domain binding	F	Interacting selectively and non-covalently with the AF-1 domain of a protein, a ligand-independent transactivation domain which is required for the full transcriptional activity of the receptor.
50684	regulation of mRNA processing	P	Any process that modulates the frequency, rate or extent of mRNA processing, those processes involved in the conversion of a primary mRNA transcript into a mature mRNA prior to its translation into polypeptide.
50685	positive regulation of mRNA processing	P	Any process that activates or increases the frequency, rate or extent of mRNA processing.
50686	negative regulation of mRNA processing	P	Any process that stops, prevents, or reduces the frequency, rate or extent of mRNA processing.
50687	negative regulation of defense response to virus	P	Any process that stops, prevents or reduces the rate or extent of antiviral mechanisms, thereby facilitating viral replication.
50688	regulation of defense response to virus	P	Any process that modulates the frequency, rate or extent of the antiviral response of a cell or organism.
50689	negative regulation of defense response to virus by host	P	Any host process that results in the inhibition of antiviral immune response mechanisms, thereby facilitating viral replication. The host is defined as the larger of the organisms involved in a symbiotic interaction.
50690	regulation of defense response to virus by virus	P	Any viral process that modulates the frequency, rate, or extent of the antiviral response of the host cell or organism.
50691	regulation of defense response to virus by host	P	Any host process that modulates the frequency, rate, or extent of the antiviral response of a host cell or organism.
50692	DBD domain binding	F	Interacting selectively and non-covalently with the DBD, DNA binding domain, of a protein. The DNA binding domain of the vitamin D receptor, one of a family of receptors with the DBD, is split into three regions, the P, D and T boxes. Residues that are critical for target sequence selectivity form the P-box. The D-box contains residues that are important for homodimerization of class I nuclear receptors. The T-box is essential for both DNA-binding and transactivation of the VDR; this region may also be important for dimerization with RXR for class II nuclear receptors.
50693	LBD domain binding	F	Interacting selectively and non-covalently with the LBD, the ligand binding domain found in nuclear receptors. In general, the LBDs consist of three layers comprised of twelve alpha-helices and several beta-strands that are organized around a lipophilic ligand-binding pocket.
50694	galactose 3-O-sulfotransferase activity	F	Catalysis of the reaction: N-acetyllactosamine + 3'-phosphoadenosine 5'-phosphosulfate = 3-sulfo-N-acetyllactosamine + adenosine 3',5'-bisphosphate. N-acetyllactosamine residues are found in a number of different carbohydrate types. N-acetyllactosamine can also be written as Gal-beta-(1,4)-GlcNAc.
50695	benzoylformate decarboxylase activity	F	Catalysis of the reaction: benzoylformate = benzaldehyde + CO2.
50696	trichloroethylene catabolic process	P	The chemical reactions and pathways resulting in the breakdown of trichloroethylene, a toxic, colorless, photoreactive, chlorinated hydrocarbon liquid, commonly used as a metal degreaser and solvent.
50697	1,1,2-trichloroethene reductive dehalogenase activity	F	Catalysis of the reaction: trichloroethene + 2 H+ + 2 e- = HCl + 1,2-dichloroethene.
50698	proteoglycan sulfotransferase activity	F	Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + proteoglycan = adenosine 3',5'-bisphosphate + proteoglycan sulfate. A proteoglycan is a glycoprotein whose carbohydrate units are glycosaminoglycans.
50699	WW domain binding	F	Interacting selectively and non-covalently with a WW domain of a protein, a small module composed of 40 amino acids and plays a role in mediating protein-protein interactions via proline-rich regions.
50700	CARD domain binding	F	Interacting selectively and non-covalently with a CARD (N-terminal caspase recruitment) domain, a protein-protein interaction domain that belongs to the death domain-fold superfamily. These protein molecule families are similar in structure with each consisting of six or seven anti-parallel alpha-helices that form highly specific homophilic interactions between signaling partners. CARD exists in the N-terminal prodomains of several caspases and in apoptosis-regulatory proteins and mediates the assembly of CARD-containing proteins that participate in activation or suppression of CARD carrying members of the caspase family.
50701	interleukin-1 secretion	P	The regulated release of interleukin-1 from a cell. Interleukin 1 is produced mainly by activated macrophages; it stimulates thymocyte proliferation by inducing interleukin 2 release and it is involved in the inflammatory response.
50702	interleukin-1 beta secretion	P	The regulated release of interleukin 1 beta from a cell.
50703	interleukin-1 alpha secretion	P	The regulated release of interleukin-1 alpha from a cell.
50704	regulation of interleukin-1 secretion	P	Any process that modulates the frequency, rate or extent of the regulated release of interleukin-1 from a cell.
50705	regulation of interleukin-1 alpha secretion	P	Any process that modulates the frequency, rate or extent of the regulated release of interleukin-1 alpha from a cell.
50706	regulation of interleukin-1 beta secretion	P	Any process that modulates the frequency, rate or extent of the regulated release of interleukin-1 beta from a cell.
50707	regulation of cytokine secretion	P	Any process that modulates the frequency, rate or extent of the regulated release of cytokines from a cell.
50708	regulation of protein secretion	P	Any process that modulates the frequency, rate or extent of the controlled release of a protein from a cell.
50709	negative regulation of protein secretion	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of a protein from a cell.
50710	negative regulation of cytokine secretion	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of cytokines from a cell.
50711	negative regulation of interleukin-1 secretion	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of interleukin-1 from a cell.
50712	negative regulation of interleukin-1 alpha secretion	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of interleukin-1 alpha from a cell.
50713	negative regulation of interleukin-1 beta secretion	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of interleukin-1 beta from a cell.
50714	positive regulation of protein secretion	P	Any process that activates or increases the frequency, rate or extent of the controlled release of a protein from a cell.
50715	positive regulation of cytokine secretion	P	Any process that activates or increases the frequency, rate or extent of the regulated release of cytokines from a cell.
50716	positive regulation of interleukin-1 secretion	P	Any process that activates or increases the frequency, rate or extent of the regulated release of interleukin-1 from a cell.
50717	positive regulation of interleukin-1 alpha secretion	P	Any process that activates or increases the frequency, rate or extent of the regulated release of interleukin-1 alpha from a cell.
50718	positive regulation of interleukin-1 beta secretion	P	Any process that activates or increases the frequency, rate or extent of the regulated release of interleukin-1 beta from a cell.
50719	interleukin-1 alpha biosynthetic process	P	The chemical reactions and pathways resulting in the formation of interleukin-1 alpha.
50720	interleukin-1 beta biosynthetic process	P	The chemical reactions and pathways resulting in the formation of interleukin-1 beta.
50721	regulation of interleukin-1 alpha biosynthetic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-1 alpha.
50722	regulation of interleukin-1 beta biosynthetic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-1 beta.
50723	negative regulation of interleukin-1 alpha biosynthetic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-1 alpha.
50724	negative regulation of interleukin-1 beta biosynthetic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-1 beta.
50725	positive regulation of interleukin-1 beta biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-1 beta.
50726	positive regulation of interleukin-1 alpha biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-1 alpha.
50727	regulation of inflammatory response	P	Any process that modulates the frequency, rate or extent of the inflammatory response, the immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents.
50728	negative regulation of inflammatory response	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the inflammatory response.
50729	positive regulation of inflammatory response	P	Any process that activates or increases the frequency, rate or extent of the inflammatory response.
50730	regulation of peptidyl-tyrosine phosphorylation	P	Any process that modulates the frequency, rate or extent of the phosphorylation of peptidyl-tyrosine.
50731	positive regulation of peptidyl-tyrosine phosphorylation	P	Any process that activates or increases the frequency, rate or extent of the phosphorylation of peptidyl-tyrosine.
50732	negative regulation of peptidyl-tyrosine phosphorylation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the phosphorylation of peptidyl-tyrosine.
50733	RS domain binding	F	Interacting selectively and non-covalently with an RS domain of a protein; RS domains are usually highly phosphorylated and characterized by the presence of arginine (R)/serine (S) dipeptides. The RS domain promotes protein-protein interactions and directs subcellular localization and, in certain situations, nucleocytoplasmic shuttling of individual SR proteins. They also play a role in splicing.
50734	hydroxycinnamoyltransferase activity	F	Catalysis of the transfer of a hydroxycinnamoyl group to an acceptor molecule.
50735	N-malonyltransferase activity	F	Catalysis of the transfer of a malonyl group to a nitrogen atom on the acceptor molecule.
50736	O-malonyltransferase activity	F	Catalysis of the transfer of a malonyl group to an oxygen atom on the acceptor molecule.
50737	O-hydroxycinnamoyltransferase activity	F	Catalysis of the transfer of a hydroxycinnamoyl group to an oxygen atom on the acceptor molecule.
50738	fructosyltransferase activity	F	Catalysis of the transfer of a fructosyl group to an acceptor molecule, typically another carbohydrate or a lipid.
50739	peptide cross-linking via S-[5'-(L-tryptoph-6'-yl)-L-tyrosin-3'-yl]-L-methionin-S-ium	P	The cross-linking of a tyrosine residue to a tryptophan residue and a methionine residue to form S-[5'-(L-tryptoph-6'-yl)-L-tyrosin-3'-yl]-L-methionin-S-ium.
50740	protein-FMN linkage via O3-riboflavin phosphoryl-L-threonine	P	The formation of a protein-FMN linkage via O3-riboflavin phosphoryl-L-threonine.
50741	protein-FMN linkage via O3-riboflavin phosphoryl-L-serine	P	The formation of a protein-FMN linkage via O3-riboflavin phosphoryl-L-serine.
50742	protein-FMN linkage via S-(4a-FMN)-L-cysteine	P	The formation of a protein-FMN linkage via S-(4a-FMN)-L-cysteine.
50743	protein-FMN linkage via 1'-(8alpha-FMN)-L-histidine	P	The formation of a protein-FMN linkage via 1'-(8alpha-FMN)-L-histidine.
50744	protein-FMN linkage via 3'-(8alpha-FMN)-L-histidine	P	The formation of a protein-FMN linkage via 3'-(8alpha-FMN)-L-histidine.
50745	peptide cross-linking via L-cysteinyl-5-imidazolinone glycine	P	The formation of a protein active site cross-link from the alpha-carboxyl carbon of residue N, a cysteine, to the alpha-amino nitrogen of residue N+2, a glycine, coupled with the formation of a double bond to the alpha-amino nitrogen of residue N+1 which loses one hydrogen, and the loss of a molecule of water.
50746	regulation of lipoprotein metabolic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving lipoproteins, any conjugated, water-soluble protein in which the nonprotein group consists of a lipid or lipids.
50747	positive regulation of lipoprotein metabolic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving lipoproteins, any conjugated, water-soluble protein in which the nonprotein group consists of a lipid or lipids.
50748	negative regulation of lipoprotein metabolic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving lipoproteins, any conjugated, water-soluble protein in which the nonprotein group consists of a lipid or lipids.
50750	low-density lipoprotein particle receptor binding	F	Interacting selectively and non-covalently with a low-density lipoprotein receptor.
50751	fractalkine biosynthetic process	P	The chemical reactions and pathways resulting in the formation of fractalkine, a chemokine involved in the control of the key regulatory mechanisms of cell trafficking at sites of inflammation. It exists as a secreted protein and in a membrane-bound form, and exhibits a novel C-X-X-X-C cysteine signature motif. The counterpart of human fractalkine is murine neurotactin; fractalkine is also referred to as CX3C membrane-anchored chemokine or ABCD-3 and has been renamed CX3CL1.
50752	regulation of fractalkine biosynthetic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of fractalkine, a chemokine involved in the control of the key regulatory mechanisms of cell trafficking at sites of inflammation.
50753	negative regulation of fractalkine biosynthetic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of fractalkine, a chemokine involved in the control of the key regulatory mechanisms of cell trafficking at sites of inflammation.
50754	positive regulation of fractalkine biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of fractalkine, a chemokine involved in the control of the key regulatory mechanisms of cell trafficking at sites of inflammation.
50755	chemokine metabolic process	P	The chemical reactions and pathways involving chemokines, any member of a family of small chemotactic cytokines; their name is derived from their ability to induce directed chemotaxis in nearby responsive cells. All chemokines possess a number of conserved cysteine residues involved in intramolecular disulfide bond formation. Some chemokines are considered pro-inflammatory and can be induced during an immune response to recruit cells of the immune system to a site of infection, while others are considered homeostatic and are involved in controlling the migration of cells during normal processes of tissue maintenance or development. Chemokines are found in all vertebrates, some viruses and some bacteria.
50756	fractalkine metabolic process	P	The chemical reactions and pathways involving fractalkine, a chemokine involved in the control of the key regulatory mechanisms of cell trafficking at sites of inflammation. It exists as a secreted protein and in a membrane-bound form, and exhibits a novel C-X-X-X-C cysteine signature motif. The counterpart of human fractalkine is murine neurotactin; fractalkine is also referred to as CX3C membrane-anchored chemokine or ABCD-3 and has been renamed CX3CL1.
50757	thymidylate synthase biosynthetic process	P	The chemical reactions and pathways resulting in the formation of the enzyme thymidylate synthase, which catalyzes the reaction: 5,10-methylenetetrahydrofolate + dUMP = dihydrofolate + dTMP.
50758	regulation of thymidylate synthase biosynthetic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of the enzyme thymidylate synthase.
50759	positive regulation of thymidylate synthase biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of the enzyme thymidylate synthase.
50760	negative regulation of thymidylate synthase biosynthetic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of the enzyme thymidylate synthase.
50761	depsipeptide metabolic process	P	The chemical reactions and pathways involving depsipeptides, a linear or cyclic compound composed of both amino acids and hydroxy acids in peptide and ester bonds respectively.
50762	depsipeptide catabolic process	P	The chemical reactions and pathways resulting in the breakdown of depsipeptides, a linear or cyclic compound composed of both amino acids and hydroxy acids in peptide and ester bonds respectively.
50763	depsipeptide biosynthetic process	P	The chemical reactions and pathways resulting in the formation of depsipeptides, a linear or cyclic compound composed of both amino acids and hydroxy acids in peptide and ester bonds respectively.
50764	regulation of phagocytosis	P	Any process that modulates the frequency, rate or extent of phagocytosis, the process in which phagocytes engulf external particulate material.
50765	negative regulation of phagocytosis	P	Any process that stops, prevents, or reduces the frequency, rate or extent of phagocytosis.
50766	positive regulation of phagocytosis	P	Any process that activates or increases the frequency, rate or extent of phagocytosis.
50767	regulation of neurogenesis	P	Any process that modulates the frequency, rate or extent of neurogenesis, the origin and formation of neurons.
50768	negative regulation of neurogenesis	P	Any process that stops, prevents, or reduces the frequency, rate or extent of neurogenesis, the origin and formation of neurons.
50769	positive regulation of neurogenesis	P	Any process that activates or increases the frequency, rate or extent of neurogenesis, the origin and formation of neurons.
50770	regulation of axonogenesis	P	Any process that modulates the frequency, rate or extent of axonogenesis, the generation of an axon, the long process of a neuron.
50771	negative regulation of axonogenesis	P	Any process that stops, prevents, or reduces the frequency, rate or extent of axonogenesis.
50772	positive regulation of axonogenesis	P	Any process that activates or increases the frequency, rate or extent of axonogenesis.
50773	regulation of dendrite development	P	Any process that modulates the frequency, rate or extent of dendrite development.
50774	negative regulation of dendrite morphogenesis	P	Any process that stops, prevents, or reduces the frequency, rate or extent of dendrite morphogenesis.
50775	positive regulation of dendrite morphogenesis	P	Any process that activates or increases the frequency, rate or extent of dendrite morphogenesis.
50776	regulation of immune response	P	Any process that modulates the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus.
50777	negative regulation of immune response	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus.
50778	positive regulation of immune response	P	Any process that activates or increases the frequency, rate or extent of the immune response, the immunological reaction of an organism to an immunogenic stimulus.
50779	RNA destabilization	P	Any process that decreases the stability of an RNA molecule, making it more vulnerable to degradative processes.
50780	dopamine receptor binding	F	Interacting selectively and non-covalently with a dopamine receptor.
50781	ortho-trichlorophenol reductive dehalogenase activity	F	Catalysis of the reaction: 2,4,6-trichlorophenol + 2 H+ + 2 e- = 2,4-dichlorophenol + HCl.
50782	galactose uniporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: galactose (out) = galactose(in).
50783	cocaine metabolic process	P	The chemical reactions and pathways involving cocaine, an alkaloid obtained from the dried leaves of the shrub Erythroxylon coca. It is a cerebral stimulant and narcotic.
50784	cocaine catabolic process	P	The chemical reactions and pathways resulting in the breakdown of cocaine, an alkaloid obtained from the dried leaves of the shrub Erythroxylon coca. It is a cerebral stimulant and narcotic.
50785	advanced glycation end-product receptor activity	F	Combining with advanced glycation end-products and transmitting the signal to initiate a change in cell activity. Advanced glycation end-products (AGEs) form from a series of chemical reactions after an initial glycation event (a non-enzymatic reaction between reducing sugars and free amino groups of proteins).
50786	RAGE receptor binding	F	Interacting selectively and non-covalently with the RAGE receptor, the receptor for advanced glycation end-products.
50787	detoxification of mercury ion	P	Any process that reduce or remove the toxicity of mercuric ion. These include transport of mercury away from sensitive areas and to compartments or complexes whose purpose is sequestration of mercury ion and/or reduction of mercury ion (Hg[II]) to metallic mercury (Hg[0]).
50788	sequestering of mercury	P	The process of binding or confining toxic mercury ions or atoms such that they are separated from sensitive components of a biological system.
50789	regulation of biological process	P	Any process that modulates the frequency, rate or extent of a biological process. Biological processes are regulated by many means; examples include the control of gene expression, protein modification or interaction with a protein or substrate molecule.
50790	regulation of catalytic activity	P	Any process that modulates the activity of an enzyme.
50792	regulation of viral process	P	Any process that modulates the rate or extent of the viral life cycle, the set of processes by which a virus reproduces and spreads among hosts.
50793	regulation of developmental process	P	Any process that modulates the frequency, rate or extent of development, the biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).
50794	regulation of cellular process	P	Any process that modulates the frequency, rate or extent of a cellular process, any of those that are carried out at the cellular level, but are not necessarily restricted to a single cell. For example, cell communication occurs among more than one cell, but occurs at the cellular level.
50795	regulation of behavior	P	Any process that modulates the frequency, rate or extent of behavior, the internally coordinated responses (actions or inactions) of whole living organisms (individuals or groups) to internal or external stimuli.
50796	regulation of insulin secretion	P	Any process that modulates the frequency, rate or extent of the regulated release of insulin.
50797	thymidylate synthase (FAD) activity	F	Catalysis of the reaction: 5,10-methylenetetrahydrofolate + dUMP + NADPH + H+ = dTMP + tetrahydrofolate + NADP+.
50798	activated T cell proliferation	P	The expansion of a T cell population following activation by an antigenic stimulus.
50799	cocaine biosynthetic process	P	The chemical reactions and pathways resulting in the formation of cocaine, an alkaloid obtained from the dried leaves of the shrub Erythroxylon coca. It is a cerebral stimulant and narcotic.
50801	ion homeostasis	P	Any process involved in the maintenance of an internal steady state of ions within an organism or cell.
50802	circadian sleep/wake cycle, sleep	P	The part of the circadian sleep/wake cycle where the organism is asleep.
50803	regulation of synapse structure or activity	P	Any process that modulates the physical form or the activity of a synapse, the junction between a neuron and a target (neuron, muscle, or secretory cell).
50804	modulation of synaptic transmission	P	Any process that modulates the frequency or amplitude of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse. Amplitude, in this case, refers to the change in postsynaptic membrane potential due to a single instance of synaptic transmission.
50805	negative regulation of synaptic transmission	P	Any process that stops, prevents, or reduces the frequency, rate or extent of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse.
50806	positive regulation of synaptic transmission	P	Any process that activates or increases the frequency, rate or extent of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse.
50807	regulation of synapse organization	P	Any process that modulates the physical form of a synapse, the junction between a neuron and a target (neuron, muscle, or secretory cell).
50808	synapse organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a synapse, the junction between a neuron and a target (neuron, muscle, or secretory cell).
50809	diazepam binding	F	Interacting selectively and non-covalently with diazepam, one of the most widely used benzodiazepine drugs. It is used as an anti-anxiety-hypnotic agent and has the proprietary name Valium.
50810	regulation of steroid biosynthetic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus.
50811	GABA receptor binding	F	Interacting selectively and non-covalently with the gamma-aminobutyric acid (GABA, 4-aminobutyrate) receptor.
50812	regulation of acyl-CoA biosynthetic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of acyl-CoA.
50813	epothilone metabolic process	P	The chemical reactions and pathways involving epothilone, a drug obtained from the myxobacteria Sporangium cellulosum that interferes with cell division. Some epothilones are being studied as treatments for cancer.
50814	epothilone biosynthetic process	P	The chemical reactions and pathways resulting in the formation of epothilone, a drug obtained from the myxobacteria Sporangium cellulosum that interferes with cell division. Some epothilones are being studied as treatments for cancer.
50815	phosphoserine binding	F	Interacting selectively and non-covalently with a phosphorylated serine residue within a protein.
50816	phosphothreonine binding	F	Interacting selectively and non-covalently with a phosphorylated threonine residue within a protein.
50817	coagulation	P	The process in which a fluid solution, or part of it, changes into a solid or semisolid mass.
50818	regulation of coagulation	P	Any process that modulates the frequency, rate or extent of coagulation, the process in which a fluid solution, or part of it, changes into a solid or semisolid mass.
50819	negative regulation of coagulation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of coagulation.
50820	positive regulation of coagulation	P	Any process that activates or increases the frequency, rate or extent of coagulation.
50821	protein stabilization	P	Any process involved in maintaining the structure and integrity of a protein and preventing it from degradation or aggregation.
50822	peptide stabilization	P	Any process involved in maintaining the structure and integrity of a peptide and preventing it from being degraded.
50823	peptide antigen stabilization	P	Any process involved in maintaining the structure and integrity of a peptide antigen and preventing it from being degraded.
50824	water binding	F	Interacting selectively and non-covalently with water (H2O).
50825	ice binding	F	Interacting selectively and non-covalently with ice, water reduced to the solid state by cold temperature. It is a white or transparent colorless substance, crystalline, brittle, and viscoidal.
50826	response to freezing	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a freezing stimulus, temperatures below 0 degrees Celsius.
50828	regulation of liquid surface tension	P	Any process that modulates the surface tension of a liquid. Surface tension is the property that makes a liquid behave as if it had an elastic skin on its surface at the interface with a gas or an immiscible liquid.
50829	defense response to Gram-negative bacterium	P	Reactions triggered in response to the presence of a Gram-negative bacterium that act to protect the cell or organism.
50830	defense response to Gram-positive bacterium	P	Reactions triggered in response to the presence of a Gram-positive bacterium that act to protect the cell or organism.
50831	male-specific defense response to bacterium	P	A set of reactions, specific to males, that are triggered in response to the presence of a bacterium that act to protect the cell or organism.
50832	defense response to fungus	P	Reactions triggered in response to the presence of a fungus that act to protect the cell or organism.
50833	pyruvate transmembrane transporter activity	F	Enables the transfer of pyruvate, 2-oxopropanoate, from one side of the membrane to the other.
50834	molybdenum incorporation via L-cysteinyl copper sulfido molybdopterin cytosine dinucleotide	P	The incorporation of molybdenum into a protein by L-cysteinyl copper sulfido molybdopterin cytosine dinucleotide.
50835	iron incorporation into iron-sulfur cluster via tris-L-cysteinyl S-adenosylmethion-N,O-diyl tetrairon tetrasulfide	P	The incorporation of iron into a 4Fe-4S iron-sulfur cluster via tris-L-cysteinyl S-adenosylmethion-N,O-diyl tetrairon tetrasulfide.
50836	iron incorporation into iron-sulfur cluster via tris-L-cysteinyl L-arginyl diiron disulfide	P	The incorporation of iron into a 4Fe-4S iron-sulfur cluster via tris-L-cysteinyl L-arginyl diiron disulfide.
50837	peptide cross-linking via L-cysteinyl-L-selenocysteine	P	The formation of a selenide-sulfide bond to form the cystine-like L-cysteinyl-L-selenocysteine, as in vertebrate selenopeptide P.
50838	peptidyl-5-hydroxy-L-lysine trimethylation	P	The methylation of 5-hydroxy-L-lysine to form peptidyl-N6,N6,N6-trimethyl-5-hydroxy-L-lysine.
50839	cell adhesion molecule binding	F	Interacting selectively and non-covalently with a cell adhesion molecule.
50840	extracellular matrix binding	F	Interacting selectively and non-covalently with a component of the extracellular matrix.
50841	peptidyl-N6,N6,N6-trimethyl-lysine hydroxylation to peptidyl-N6,N6,N6-trimethyl-5-hydroxy-L-lysine	P	The hydroxylation of peptidyl-N6,N6,N6-trimethyl-L-lysine to form peptidyl-N6,N6,N6-trimethyl-5-hydroxy-L-lysine.
50842	copper incorporation via L-cysteinyl copper sulfido molybdopterin cytosine dinucleotide	P	The incorporation of copper into a protein by L-cysteinyl copper sulfido molybdopterin cytosine dinucleotide.
50843	S-adenosylmethionine catabolic process	P	The chemical reactions and pathways resulting in the breakdown of S-adenosylmethionine, S-(5'-adenosyl)-L-methionine, an important intermediate in one-carbon metabolism.
50844	peptidyl-selenocysteine modification	P	The modification of peptidyl-selenocysteine.
50845	teichuronic acid biosynthetic process	P	The chemical reactions and pathways resulting in the formation of teichuronic acid, a polymer containing chains of uronic acids and N-acetylglucosamine found in the cell wall, membrane or capsule of Gram-positive bacteria.
50846	teichuronic acid metabolic process	P	The chemical reactions and pathways involving teichuronic acid, a polymer containing chains of uronic acids and N-acetylglucosamine found in the cell wall, membrane or capsule of Gram-positive bacteria.
50847	progesterone receptor signaling pathway	P	Any series of molecular signals generated as a consequence of a progesterone binding to its receptor.
50848	regulation of calcium-mediated signaling	P	Any process that modulates the frequency, rate or extent of calcium-mediated signaling, the process in which a cell uses calcium ions to convert an extracellular signal into a response.
50849	negative regulation of calcium-mediated signaling	P	Any process that stops, prevents, or reduces the frequency, rate or extent of calcium-mediated signaling.
50850	positive regulation of calcium-mediated signaling	P	Any process that activates or increases the frequency, rate or extent of calcium-mediated signaling.
50851	antigen receptor-mediated signaling pathway	P	A series of molecular signals initiated by the cross-linking of an antigen receptor on a B or T cell.
50852	T cell receptor signaling pathway	P	A series of molecular signals initiated by the cross-linking of an antigen receptor on a T cell.
50853	B cell receptor signaling pathway	P	A series of molecular signals initiated by the cross-linking of an antigen receptor on a B cell.
50854	regulation of antigen receptor-mediated signaling pathway	P	Any process that modulates the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a B- or T cell.
50855	regulation of B cell receptor signaling pathway	P	Any process that modulates the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a B cell.
50856	regulation of T cell receptor signaling pathway	P	Any process that modulates the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a T cell.
50857	positive regulation of antigen receptor-mediated signaling pathway	P	Any process that activates or increases the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a B- or T cell.
50858	negative regulation of antigen receptor-mediated signaling pathway	P	Any process that stops, prevents, or reduces the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a B- or T cell.
50859	negative regulation of B cell receptor signaling pathway	P	Any process that stops, prevents, or reduces the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a B cell.
50860	negative regulation of T cell receptor signaling pathway	P	Any process that stops, prevents, or reduces the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a T cell.
50861	positive regulation of B cell receptor signaling pathway	P	Any process that activates or increases the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a B cell.
50862	positive regulation of T cell receptor signaling pathway	P	Any process that activates or increases the frequency, rate or extent of signaling pathways initiated by the cross-linking of an antigen receptor on a T cell.
50863	regulation of T cell activation	P	Any process that modulates the frequency, rate or extent of T cell activation.
50864	regulation of B cell activation	P	Any process that modulates the frequency, rate or extent of B cell activation.
50865	regulation of cell activation	P	Any process that modulates the frequency, rate or extent of cell activation, the change in the morphology or behavior of a cell resulting from exposure to an activating factor such as a cellular or soluble ligand.
50866	negative regulation of cell activation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of cell activation.
50867	positive regulation of cell activation	P	Any process that activates or increases the frequency, rate or extent of activation.
50868	negative regulation of T cell activation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of T cell activation.
50869	negative regulation of B cell activation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of B cell activation.
50870	positive regulation of T cell activation	P	Any process that activates or increases the frequency, rate or extent of T cell activation.
50871	positive regulation of B cell activation	P	Any process that activates or increases the frequency, rate or extent of B cell activation.
50872	white fat cell differentiation	P	The process in which a relatively unspecialized cell acquires specialized features of a white adipocyte, an animal connective tissue cell involved in energy storage. White adipocytes have cytoplasmic lipids arranged in a unique vacuole.
50873	brown fat cell differentiation	P	The process in which a relatively unspecialized cell acquires specialized features of a brown adipocyte, an animal connective tissue cell involved in adaptive thermogenesis. Brown adipocytes contain multiple small droplets of triglycerides and a high number of mitochondria.
50877	neurological system process	P	A organ system process carried out by any of the organs or tissues of neurological system.
50878	regulation of body fluid levels	P	Any process that modulates the levels of body fluids.
50879	multicellular organismal movement	P	Any physiological process involved in changing the position of a multicellular organism or an anatomical part of a multicellular organism.
50880	regulation of blood vessel size	P	Any process that modulates the size of blood vessels.
50881	musculoskeletal movement	P	The movement of an organism or part of an organism using mechanoreceptors, the nervous system, striated muscle and/or the skeletal system.
50882	voluntary musculoskeletal movement	P	The movement of an organism or part of an organism using mechanoreceptors, the nervous system, striated muscle and/or the skeletal system that can be controlled at will.
50883	musculoskeletal movement, spinal reflex action	P	Involuntary movement caused by the application of a stimulus to an organism and a subsequent movement. The signal processing of this movement takes place in the spinal cord.
50884	neuromuscular process controlling posture	P	Any process in which an organism voluntarily modulates its posture, the alignment of its anatomical parts.
50885	neuromuscular process controlling balance	P	Any process that an organism uses to control its balance, the orientation of the organism (or the head of the organism) in relation to the source of gravity. In humans and animals, balance is perceived through visual cues, the labyrinth system of the inner ears and information from skin pressure receptors and muscle and joint receptors.
50886	endocrine process	P	The process that involves the secretion of or response to endocrine hormones. An endocrine hormone is a hormone released into the circulatory system.
50887	determination of sensory modality	P	The determination of the type or quality of a sensation. Sensory modalities include touch, thermal sensation, visual sensation, auditory sensation and pain.
50888	determination of stimulus location	P	The determination of where on the body surface, within the body or in the environment a stimulus originates.
50889	determination of stimulus intensity	P	The determination of the perceived strength of a sensory stimulus.
50890	cognition	P	The operation of the mind by which an organism becomes aware of objects of thought or perception; it includes the mental activities associated with thinking, learning, and memory.
50891	multicellular organismal water homeostasis	P	Any process involved in the maintenance of an internal steady state of water within a tissue, organ, or a multicellular organism.
50892	intestinal absorption	P	Any process in which nutrients are taken up from the contents of the intestine.
50893	sensory processing	P	Any neural process required for an organism to sense and interpret the dimensions of a sensory experience: modality, location, intensity and affect.
50894	determination of affect	P	Any process in which an emotional response is associated with a particular sensory stimulation.
50896	response to stimulus	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus and ends with a change in state or activity or the cell or organism.
50897	cobalt ion binding	F	Interacting selectively and non-covalently with a cobalt (Co) ion.
50898	nitrile metabolic process	P	The chemical reactions and pathways involving nitriles, an organic compound containing trivalent nitrogen attached to one carbon atom. The nitriles are named with reference to the acids produced by their decomposition; for example, hydrocyanic acid is formic nitrile, and methyl cyanide is acetic nitrile.
50899	nitrile catabolic process	P	The chemical reactions and pathways resulting in the breakdown of a nitrile, an organic compound containing trivalent nitrogen attached to one carbon atom.
50900	leukocyte migration	P	The movement of a leukocyte within or between different tissues and organs of the body.
50901	leukocyte tethering or rolling	P	Transient adhesive interactions between leukocytes and endothelial cells lining blood vessels. Carbohydrates on circulating leukocytes bind selectins on the vessel wall causing the leukocytes to slow down and roll along the inner surface of the vessel wall. During this rolling motion, transitory bonds are formed and broken between selectins and their ligands. Typically the first step in cellular extravasation (the movement of leukocytes out of the circulatory system, towards the site of tissue damage or infection).
50902	leukocyte adhesive activation	P	The activation of loosely bound or rolling leukocytes by signals displayed on blood vessel endothelial cells, which is typically the second step in cellular extravasation.
50903	leukocyte activation-dependent arrest	P	The formation of an integrin-dependent strong adhesive bond between leukocytes and blood vessel endothelial cells which is dependent on prior activation of the leukocyte and leads to the firm attachment of the leukocyte to the endothelial surface, typically the third step in cellular extravasation.
50904	diapedesis	P	The passage of a leukocyte between the tight junctions of endothelial cells lining blood vessels, typically the fourth and final step of cellular extravasation.
50905	neuromuscular process	P	Any process pertaining to the functions of the nervous and muscular systems of an organism.
50906	detection of stimulus involved in sensory perception	P	The series of events involved in sensory perception in which a sensory stimulus is received and converted into a molecular signal.
50907	detection of chemical stimulus involved in sensory perception	P	The series of events in which a chemical stimulus is received and converted into a molecular signal as part of sensory perception.
50908	detection of light stimulus involved in visual perception	P	The series of events involved in visual perception in which a light stimulus is received and converted into a molecular signal.
50909	sensory perception of taste	P	The series of events required for an organism to receive a gustatory stimulus, convert it to a molecular signal, and recognize and characterize the signal. Gustation involves the direct detection of chemical composition, usually through contact with chemoreceptor cells. This is a neurological process.
50910	detection of mechanical stimulus involved in sensory perception of sound	P	The series of events involved in the perception of sound vibration in which the vibration is received and converted into a molecular signal.
50911	detection of chemical stimulus involved in sensory perception of smell	P	The series of events involved in the perception of smell in which an olfactory chemical stimulus is received and converted into a molecular signal.
50912	detection of chemical stimulus involved in sensory perception of taste	P	The series of events involved in the perception of taste in which a gustatory chemical stimulus is received and converted into a molecular signal.
50913	sensory perception of bitter taste	P	The series of events required to receive a bitter taste stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process.
50914	sensory perception of salty taste	P	The series of events required to receive a salty taste stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process.
50915	sensory perception of sour taste	P	The series of events required to receive a sour taste stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process.
50916	sensory perception of sweet taste	P	The series of events required to receive a sweet taste stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process.
50917	sensory perception of umami taste	P	The series of events required to receive an umami taste stimulus, convert it to a molecular signal, and recognize and characterize the signal. Umami taste is the savory taste of meats and other foods that are rich in glutamates. This is a neurological process.
50918	positive chemotaxis	P	The directed movement of a motile cell or organism towards a higher concentration of a chemical.
50919	negative chemotaxis	P	The directed movement of a motile cell or organism towards a lower concentration of a chemical.
50920	regulation of chemotaxis	P	Any process that modulates the frequency, rate or extent of the directed movement of a motile cell or organism in response to a specific chemical concentration gradient.
50921	positive regulation of chemotaxis	P	Any process that activates or increases the frequency, rate or extent of the directed movement of a motile cell or organism in response to a specific chemical concentration gradient.
50922	negative regulation of chemotaxis	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a motile cell or organism in response to a specific chemical concentration gradient.
50923	regulation of negative chemotaxis	P	Any process that modulates the frequency, rate or extent of the directed movement of a motile cell or organism towards a lower concentration in a concentration gradient of a specific chemical.
50924	positive regulation of negative chemotaxis	P	Any process that activates or increases the frequency, rate or extent of the directed movement of a motile cell or organism towards a lower concentration in a concentration gradient of a specific chemical.
50925	negative regulation of negative chemotaxis	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a motile cell or organism towards a lower concentration in a concentration gradient of a specific chemical.
50926	regulation of positive chemotaxis	P	Any process that modulates the frequency, rate or extent of the directed movement of a motile cell or organism towards a higher concentration in a concentration gradient of a specific chemical.
50927	positive regulation of positive chemotaxis	P	Any process that activates or increases the frequency, rate or extent of the directed movement of a motile cell or organism towards a higher concentration in a concentration gradient of a specific chemical.
50928	negative regulation of positive chemotaxis	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a motile cell or organism towards a higher concentration in a concentration gradient of a specific chemical.
50929	induction of negative chemotaxis	P	Any process that initiates the directed movement of a motile cell or organism towards a lower concentration in a concentration gradient of a specific chemical.
50930	induction of positive chemotaxis	P	Any process that initiates the directed movement of a motile cell or organism towards a higher concentration in a concentration gradient of a specific chemical.
50931	pigment cell differentiation	P	The process in which a relatively unspecialized cell acquires the specialized features of a pigmented cell, such as a melanocyte.
50932	regulation of pigment cell differentiation	P	Any process that modulates the frequency, rate or extent of pigmented cell differentiation.
50933	early stripe melanocyte differentiation	P	The process in which a relatively unspecialized cell acquires the specialized features of an early stripe melanocyte (ESM). In zebrafish, ESMs develop during the first phase (2-3 weeks of development) of the larva to adult transition (2-4 weeks of development).
50934	late stripe melanocyte differentiation	P	The process in which a relatively unspecialized cell acquires the specialized features of a late stripe melanocyte (LSM). In zebrafish, LSMs develop during the second phase (3-4 weeks of development) of the larva-to-adult transition (2-4 weeks of development).
50935	iridophore differentiation	P	The process in which a relatively unspecialized cell acquires the specialized features of an iridophore. Iridophores are pigment cells derived from the neural crest. They contain guanidine or other purine crystals deposited in stacks called reflecting platets or iridisomes. This gives them a silver, gold, or iridescent appearance.
50936	xanthophore differentiation	P	The process in which a relatively unspecialized cell acquires the specialized features of a xanthophore cell. Xanthophores are pigment cells derived from the neural crest. They contain pteridine and/or carotenoid pigments in structures called pterinosomes or xanthosomes. This makes them yellow to orange in appearance.
50937	regulation of iridophore differentiation	P	Any process that modulates the frequency, rate or extent of iridophore differentiation.
50938	regulation of xanthophore differentiation	P	Any process that modulates the frequency, rate or extent of xanthophore differentiation.
50939	regulation of early stripe melanocyte differentiation	P	Any process that modulates the frequency, rate or extent of early stripe melanocyte differentiation.
50940	regulation of late stripe melanocyte differentiation	P	Any process that modulates the frequency, rate or extent of late stripe melanocyte differentiation.
50941	negative regulation of pigment cell differentiation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of pigment cell differentiation.
50942	positive regulation of pigment cell differentiation	P	Any process that activates or increases the frequency, rate or extent of pigment cell differentiation.
50943	negative regulation of iridophore differentiation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of iridophore differentiation.
50944	negative regulation of xanthophore differentiation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of xanthophore differentiation.
50945	positive regulation of iridophore differentiation	P	Any process that activates or increases the frequency, rate or extent of iridophore differentiation.
50946	positive regulation of xanthophore differentiation	P	Any process that activates or increases the frequency, rate or extent of xanthophore differentiation.
50947	negative regulation of early stripe melanocyte differentiation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of early stripe melanocyte differentiation.
50948	positive regulation of early stripe melanocyte differentiation	P	Any process that activates or increases the frequency, rate or extent of early stripe melanocyte differentiation.
50949	negative regulation of late stripe melanocyte differentiation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of late stripe melanocyte differentiation.
50950	positive regulation of late stripe melanocyte differentiation	P	Any process that activates or increases the frequency, rate or extent of late stripe melanocyte differentiation.
50951	sensory perception of temperature stimulus	P	The series of events required for an organism to receive a sensory temperature stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process.
50952	sensory perception of electrical stimulus	P	The series of events required for an organism to receive a sensory electrical stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process.
50953	sensory perception of light stimulus	P	The series of events required for an organism to receive a sensory light stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process.
50954	sensory perception of mechanical stimulus	P	The series of events required for an organism to receive a sensory mechanical stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process.
50955	thermoception	P	The series of events required for an organism to receive a temperature stimulus, convert it to a molecular signal, and recognize and characterize the signal. Thermoception in larger animals is mainly done in the skin; mammals have at least two types of sensor, for detecting heat (temperatures above body temperature) and cold (temperatures below body temperature).
50956	electroception	P	The series of events required for an organism to receive an electrical stimulus, convert it to a molecular signal, and recognize and characterize the signal. Many fish possess an electroception sense; for example, the electric eel uses low voltage pulses of electricity for navigation and prey location.
50957	equilibrioception	P	The series of events required for an organism to receive an orientational stimulus, convert it to a molecular signal, and recognize and characterize the signal. Equilibrioception refers to a combination of processes by which an organism can perceive its orientation with respect to gravity. In animals, stimuli come from labyrinth system of the inner ears, monitoring the direction of motion; visual stimuli, with information on orientation and motion; pressure receptors, which tell the organism which body surfaces are in contact with the ground; and proprioceptive cues, which report which parts of the body are in motion.
50958	magnetoreception	P	The series of events required for an organism to receive a stimulus relating to a magnetic field, convert it to a molecular signal, and recognize and characterize the signal. Stimuli may be chemical, mechanical or electrical and interpreting these stimuli allows an organism to determine the orientation of a magnetic field. Magnetoreception also involves the perception of light; birds cannot orient without the presence of short wavelength (blue/green) light.
50959	echolocation	P	Echolocation is the method used by some animals (e.g. bats, dolphins and some whales) to determine the location of something by measuring the time it takes for an echo to return from it. These animals emit sound waves and listen for the echo, calculating the distance to the object from the time lapse between sound emission and the echo returning.
50960	detection of temperature stimulus involved in thermoception	P	The series of events in which a temperature stimulus is received and converted into a molecular signal as part of thermoception.
50961	detection of temperature stimulus involved in sensory perception	P	The series of events in which a temperature stimulus is received and converted into a molecular signal as part of sensory perception.
50962	detection of light stimulus involved in sensory perception	P	The series of events in which a light stimulus is received by a cell and converted into a molecular signal as part of the sensory perception of light.
50963	detection of electrical stimulus involved in sensory perception	P	The series of events in which an electrical stimulus is received by a cell and converted into a molecular signal as part of sensory perception.
50964	detection of electrical stimulus involved in electroception	P	The series of events that contribute to electroception in which an electrical stimulus is received and converted into a molecular signal.
50965	detection of temperature stimulus involved in sensory perception of pain	P	The series of events involved in the perception of pain in which a temperature stimulus is received and converted into a molecular signal.
50966	detection of mechanical stimulus involved in sensory perception of pain	P	The series of events involved in the perception of pain in which a mechanical stimulus is received and converted into a molecular signal.
50967	detection of electrical stimulus involved in sensory perception of pain	P	The series of events that contribute to the perception of pain in which an electrical stimulus is received and converted into a molecular signal.
50968	detection of chemical stimulus involved in sensory perception of pain	P	The series of events involved in the perception of pain in which a chemical stimulus is received and converted into a molecular signal.
50969	detection of chemical stimulus involved in magnetoreception	P	The series of events involved in magnetoception in which a chemical stimulus is received and converted into a molecular signal. It is believed that organisms such as birds and salamanders interpret product ratios in chemical reactions which involve transitions between different spin states.
50970	detection of electrical stimulus involved in magnetoreception	P	The series of events that contribute to magnetoception in which an electrical stimulus is received and converted into a molecular signal. The stimulus is in the form of an induced electric field resulting from movement in a magnetic field.
50971	detection of mechanical stimulus involved in magnetoreception	P	The series of events involved in magnetoception in which a mechanical stimulus is received and converted into a molecular signal. The stimulus is in the form of torque on particles such as magnetite which respond to a magnetic field.
50972	detection of mechanical stimulus involved in echolocation	P	The series of events involved in echolocation in which a mechanical stimulus is received and converted into a molecular signal. The stimulus is in the form of a reflected sound wave (an echo), which the organism uses to determine the distance to the object that reflected the sound wave.
50973	detection of mechanical stimulus involved in equilibrioception	P	The series of events involved in equilibrioception in which a mechanical stimulus is received and converted into a molecular signal. During equilibrioception, mechanical stimuli may be in the form of input from pressure receptors or from the labyrinth system of the inner ears.
50974	detection of mechanical stimulus involved in sensory perception	P	The series of events in which a mechanical stimulus is received and converted into a molecular signal as part of sensory perception.
50975	sensory perception of touch	P	The series of events required for an organism to receive a touch stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process. The perception of touch in animals is mediated by mechanoreceptors in the skin and mucous membranes and is the sense by which contact with objects gives evidence as to certain of their qualities. Different types of touch can be perceived (for example, light, coarse, pressure and tickling) and the stimulus may be external or internal (e.g. the feeling of a full stomach).
50976	detection of mechanical stimulus involved in sensory perception of touch	P	The series of events involved in the perception of touch in which a mechanical stimulus is received and converted into a molecular signal.
50977	magnetoreception by sensory perception of chemical stimulus	P	The series of events required for an organism to receive a chemical stimulus relating to a magnetic field, convert it to a molecular signal, and recognize and characterize the signal. It is believed that organisms such as birds and salamanders use a 'chemical compass': chemical reactions that involve transitions between different spin states can be influenced by magnetic fields and by detecting the different product ratios, these organisms can perceive the direction of the magnetic field. The mechanism by which this is detected is not certain but it may also involve light stimuli.
50978	magnetoreception by sensory perception of electrical stimulus	P	The series of events required for an organism to receive an electrical stimulus relating to a magnetic field, convert it to a molecular signal, and recognize and characterize the signal. Movement in a magnetic field results in an induced electric field, which can be perceived by organisms such as elasmobranch fish.
50979	magnetoreception by sensory perception of mechanical stimulus	P	The series of events required for an organism to receive a mechanical stimulus relating to a magnetic field, convert it to a molecular signal, and recognize and characterize the signal. A magnetic field exerts a torque on a ferromagnetic material (e.g. magnetite) or on a material with diamagnetic anisotropy; organisms that can detect this torque can use it to determine the orientation of the magnetic field.
50980	detection of light stimulus involved in magnetoreception	P	The series of events involved in magnetoception in which a light stimulus is received and converted into a molecular signal. Downstream processing of the light information in addition to other sensory data allows organisms to perceive the orientation of a magnetic field.
50981	detection of electrical stimulus	P	The series of events by which an electrical stimulus is received and converted into a molecular signal.
50982	detection of mechanical stimulus	P	The series of events by which a mechanical stimulus is received and converted into a molecular signal.
50984	peptidyl-serine sulfation	P	The sulfation of peptidyl-serine to form peptidyl-O-sulfo-L-serine.
50985	peptidyl-threonine sulfation	P	The sulfation of peptidyl-threonine to form peptidyl-O-sulfo-L-threonine.
50986	isopeptide cross-linking via N-(L-isoglutamyl)-glycine	P	The formation of an isopeptide cross-link between peptidyl-glutamate and peptidyl-glycine to produce N-(L-isoglutamyl)-glycine, as found in the antibiotic microcin J25.
50987	enzyme active site formation via O-sulfo-L-serine	P	The transient sulfation of peptidyl-serine to form O-sulfo-L-serine.
50988	N-terminal peptidyl-methionine carboxylation	P	The carboxylation of the N-terminal methionine of proteins to form the derivative N-carboxy-L-methionine.
50989	N-terminal protein amino acid carboxylation	P	The carboxylation of the N-terminal amino acid of proteins.
50990	N-terminal protein amino acid carbamoylation	P	The carbamoylation of the N-terminal amino acid of proteins.
50991	enzyme active site formation via O-sulfo-L-threonine	P	The transient sulfation of peptidyl-threonine to form O-sulfo-L-threonine.
50992	dimethylallyl diphosphate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of dimethylallyl diphosphate.
50993	dimethylallyl diphosphate metabolic process	P	The chemical reactions and pathways involving dimethylallyl diphosphate.
50994	regulation of lipid catabolic process	P	Any process that modulates the frequency, rate, or extent of the chemical reactions and pathways resulting in the breakdown of lipids.
50995	negative regulation of lipid catabolic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of lipids.
50996	positive regulation of lipid catabolic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the breakdown of lipids.
50997	quaternary ammonium group binding	F	Interacting selectively and non-covalently with a quaternary ammonium group, including glycine betaine, choline, carnitine and proline. A quaternary ammonium group is any compound that can be regarded as derived from ammonium hydroxide or an ammonium salt by replacement of all four hydrogen atoms of the NH4+ ion by organic groups.
50998	nitric-oxide synthase binding	F	Interacting selectively and non-covalently with the enzyme nitric-oxide synthase.
50999	regulation of nitric-oxide synthase activity	P	Any process that modulates the activity of the enzyme nitric-oxide synthase.
51000	positive regulation of nitric-oxide synthase activity	P	Any process that activates or increases the activity of the enzyme nitric-oxide synthase.
51001	negative regulation of nitric-oxide synthase activity	P	Any process that stops or reduces the activity of the enzyme nitric-oxide synthase.
51002	ligase activity, forming nitrogen-metal bonds	F	Catalysis of the joining of a metal ion to a molecule via a nitrogen-metal bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate.
51003	ligase activity, forming nitrogen-metal bonds, forming coordination complexes	F	Catalysis of the ligation of two substances via a nitrogen-metal bond, forming a coordination complex.
51004	regulation of lipoprotein lipase activity	P	Any process that modulates the activity of the enzyme lipoprotein lipase.
51005	negative regulation of lipoprotein lipase activity	P	Any process that stops or reduces the activity of the enzyme lipoprotein lipase.
51006	positive regulation of lipoprotein lipase activity	P	Any process that activates or increases the activity of the enzyme lipoprotein lipase.
51007	squalene-hopene cyclase activity	F	Catalysis of the reaction: squalene = hop-22(29)-ene.
51008	Hsp27 protein binding	F	Interacting selectively and non-covalently with Hsp27 proteins, a lightweight heat shock protein.
51009	O-acetylhomoserine sulfhydrylase activity	F	Catalysis of the reaction: O-acetyl-L-homoserine + hydrogen sulfide = homocysteine + acetate.
51010	microtubule plus-end binding	F	Interacting selectively and non-covalently with the plus end of a microtubule.
51011	microtubule minus-end binding	F	Interacting selectively and non-covalently with the minus end of a microtubule.
51012	microtubule sliding	P	The movement of one microtubule along another microtubule.
51013	microtubule severing	P	The process in which a microtubule is broken down into smaller segments.
51014	actin filament severing	P	The process in which an actin filament is broken down into smaller filaments.
51015	actin filament binding	F	Interacting selectively and non-covalently with an actin filament, also known as F-actin, a helical filamentous polymer of globular G-actin subunits.
51016	barbed-end actin filament capping	P	The binding of a protein or protein complex to the barbed (or plus) end of an actin filament, thus preventing the addition, exchange or removal of further actin subunits.
51017	actin filament bundle assembly	P	The assembly of actin filament bundles; actin filaments are on the same axis but may be oriented with the same or opposite polarities and may be packed with different levels of tightness.
51018	protein kinase A binding	F	Interacting selectively and non-covalently with any subunit of protein kinase A.
51019	mitogen-activated protein kinase binding	F	Interacting selectively and non-covalently with a mitogen-activated protein kinase.
51020	GTPase binding	F	Interacting selectively and non-covalently with a GTPase, any enzyme that catalyzes the hydrolysis of GTP.
51021	GDP-dissociation inhibitor binding	F	Interacting selectively and non-covalently with a GDP-dissociation inhibitor protein.
51022	Rho GDP-dissociation inhibitor binding	F	Interacting selectively and non-covalently with a Rho GDP-dissociation inhibitor protein.
51023	regulation of immunoglobulin secretion	P	Any process that modulates the frequency, rate or extent of the regulated release of immunoglobulins from a cell.
51024	positive regulation of immunoglobulin secretion	P	Any process that activates or increases the frequency, rate or extent of the regulated release of immunoglobulins from a cell.
51025	negative regulation of immunoglobulin secretion	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of immunoglobulins from a cell.
51026	chiasma assembly	P	The cell cycle process in which a connection between chromatids assembles, indicating where an exchange of homologous segments has taken place by the crossing-over of non-sister chromatids.
51027	DNA transport	P	The directed movement of RNA, deoxyribonucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
51028	mRNA transport	P	The directed movement of mRNA, messenger ribonucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
51029	rRNA transport	P	The directed movement of rRNA, ribosomal ribonucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
51030	snRNA transport	P	The directed movement of snRNA, small nuclear ribonucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
51031	tRNA transport	P	The directed movement of tRNA, transfer ribonucleic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
51032	nucleic acid transmembrane transporter activity	F	Enables the transfer of nucleic acids from one side of a membrane to the other. Nucleic acids are single or double-stranded polynucleotides involved in the storage, transmission and transfer of genetic information.
51033	RNA transmembrane transporter activity	F	Enables the transfer of RNA, ribonucleic acid, from one side of a membrane to the other.
51034	tRNA transmembrane transporter activity	F	Enables the transfer of tRNA, transfer ribonucleic acid, from one side of a membrane to the other.
51035	DNA transmembrane transporter activity	F	Enables the transfer of DNA, deoxyribonucleic acid, from one side of a membrane to the other.
51036	regulation of endosome size	P	Any process that modulates the volume of an endosome, a membrane-bounded organelle that carries materials newly ingested by endocytosis.
51037	regulation of transcription involved in meiotic cell cycle	P	Any process that modulates the frequency, rate or extent of transcription as part of a meiotic cell cycle.
51038	negative regulation of transcription involved in meiotic cell cycle	P	Any process that stops, prevents, or reduces the frequency, rate or extent of transcription involved in the meiotic cell cycle.
51039	positive regulation of transcription involved in meiotic cell cycle	P	Any process that activates or increases the frequency, rate or extent of transcription as part of a meiotic cell cycle.
51040	regulation of calcium-independent cell-cell adhesion	P	Any process that modulates the frequency, rate or extent of the attachment of one cell to another cell via adhesion molecules that do not require the presence of calcium for the interaction.
51041	positive regulation of calcium-independent cell-cell adhesion	P	Any process that activates or increases the frequency, rate or extent of calcium-independent cell-cell adhesion.
51042	negative regulation of calcium-independent cell-cell adhesion	P	Any process that stops, prevents, or reduces the frequency, rate or extent of calcium-independent cell-cell adhesion.
51043	regulation of membrane protein ectodomain proteolysis	P	Any process that modulates the frequency, rate or extent of the proteolytic cleavage of transmembrane proteins and release of their ectodomain (extracellular domain).
51044	positive regulation of membrane protein ectodomain proteolysis	P	Any process that activates or increases the frequency, rate or extent of membrane protein ectodomain peptidolysis.
51045	negative regulation of membrane protein ectodomain proteolysis	P	Any process that stops, prevents, or reduces the frequency, rate or extent of membrane protein ectodomain proteolysis.
51046	regulation of secretion	P	Any process that modulates the frequency, rate or extent of the controlled release of a substance from a cell or a tissue.
51047	positive regulation of secretion	P	Any process that activates or increases the frequency, rate or extent of the controlled release of a substance from a cell or a tissue.
51048	negative regulation of secretion	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of a substance from a cell or a tissue.
51049	regulation of transport	P	Any process that modulates the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
51050	positive regulation of transport	P	Any process that activates or increases the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
51051	negative regulation of transport	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of substances (such as macromolecules, small molecules, ions) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
51052	regulation of DNA metabolic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving DNA.
51053	negative regulation of DNA metabolic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving DNA.
51054	positive regulation of DNA metabolic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving DNA.
51055	negative regulation of lipid biosynthetic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of lipids.
51056	regulation of small GTPase mediated signal transduction	P	Any process that modulates the frequency, rate or extent of small GTPase mediated signal transduction.
51057	positive regulation of small GTPase mediated signal transduction	P	Any process that activates or increases the frequency, rate or extent of small GTPase mediated signal transduction.
51058	negative regulation of small GTPase mediated signal transduction	P	Any process that stops, prevents, or reduces the frequency, rate or extent of small GTPase mediated signal transduction.
51059	NF-kappaB binding	F	Interacting selectively and non-covalently with NF-kappaB, a transcription factor for eukaryotic RNA polymerase II promoters.
51060	pullulanase activity	F	Catalysis of the hydrolysis of (1,6)-alpha-D-glucosidic linkages in pullulan (a linear polymer of alpha-(1,6)-linked maltotriose units) and in amylopectin and glycogen, and the a- and b-limit dextrins of amylopectin and glycogen.
51061	ADP reductase activity	F	Catalysis of the reaction: dADP + thioredoxin disulfide + H2O = ADP + thioredoxin.
51062	UDP reductase activity	F	Catalysis of the reaction: dUDP + thioredoxin disulfide + H2O = UDP + thioredoxin.
51063	CDP reductase activity	F	Catalysis of the reaction: dCDP + thioredoxin disulfide + H2O = CDP + thioredoxin.
51064	TTP reductase activity	F	Catalysis of the reaction: dTTP + thioredoxin disulfide + H2O = TTP + thioredoxin. Thioredoxin disulfide is the oxidized form of thioredoxin.
51065	CTP reductase activity	F	Catalysis of the reaction: dCTP + thioredoxin disulfide + H2O = CTP + thioredoxin. Thioredoxin disulfide is the oxidized form of thioredoxin.
51066	dihydrobiopterin metabolic process	P	The chemical reactions and pathways involving a dihydrobiopterin, a reduced pteridine derivative related to folic acid; it acts as an electron carrier in tyrosine biosynthesis and its quinoid form is produced by oxidation of tetrahydrobiopterin in several biological hydroxylation reactions.
51067	dihydropteridine metabolic process	P	The chemical reactions and pathways involving 6,7-dihydropteridine, a bicyclic compound with the formula C6H6N4.
51068	dihydrolipoamide metabolic process	P	The chemical reactions and pathways involving dihydrolipoamide, the reduced form of lipoamide, produced as an intermediate in the reactions in which lipoamide acts as a cofactor.
51069	galactomannan metabolic process	P	The chemical reactions and pathways involving galactomannan, a polysaccharide composed of D-galactose and D-mannose. The mannose units form the backbone structure (a linear main chain) with the D-galactose as single side units.
51070	galactomannan biosynthetic process	P	The chemical reactions and pathways resulting in the formation of galactomannan, a polysaccharide composed of D-galactosyl and D-mannosyl. The mannosyl units form the backbone structure (a linear main chain) with the D-galactosyl as single side units.
51071	4,6-pyruvylated galactose residue metabolic process	P	The chemical reactions and pathways involving the pyruvylated galactose residue 4-6-O-[(R)(1-carboxyethylidine)]-Gal-beta-1,3-. The galactose residue is part of a larger polysaccharide chain.
51072	4,6-pyruvylated galactose residue biosynthetic process	P	The chemical reactions and pathways resulting in the formation of the pyruvylated galactose residue 4-6-O-[(R)(1-carboxyethylidine)]-Gal-beta-1,3-. The galactose residue is part of a larger polysaccharide chain.
51073	adenosylcobinamide-GDP ribazoletransferase activity	F	Catalysis of the reaction: adenosylcobinamide-GDP + alpha-ribazole = GMP + adenosylcobalamin.
51075	S-adenosylmethionine:tRNA ribosyltransferase-isomerase activity	F	Catalysis of the reaction: S-adenosylmethionine + 7-(aminomethyl)-7-deazaguanosine-tRNA = adenine + methionine + epoxyqueuosine-tRNA. 7-(aminomethyl)-7-deazaguanosine-tRNA is also known as preQ1-tRNA, and epoxyqueuosine-tRNA as oQ-tRNA.
51077	secondary cell septum	C	Cell wall structures composed of linear polysaccharides which are deposited at both sides of the primary septum at 90 degrees to the primary septum.
51078	meiotic nuclear envelope disassembly	P	The cell cycle process in which the controlled breakdown of the nuclear envelope during meiotic cell division occurs.
51079	meiosis I nuclear envelope disassembly	P	The controlled breakdown of the nuclear envelope during the first division of meiosis.
51080	meiosis II nuclear envelope disassembly	P	The controlled breakdown of the nuclear envelope during the second division of meiosis.
51081	nuclear envelope disassembly	P	The controlled breakdown of the nuclear envelope in the context of a normal process.
51082	unfolded protein binding	F	Interacting selectively and non-covalently with an unfolded protein.
51083	'de novo' cotranslational protein folding	P	The process of assisting in the correct noncovalent assembly of the ribosome-bound nascent chains of a multidomain protein whilst other parts of the protein are still being translated.
51084	'de novo' posttranslational protein folding	P	The process of assisting in the correct noncovalent folding of newly formed polypeptides or folding intermediates of polypeptides that have exited the ribosome and/or have been stabilized and transferred by other chaperone proteins. This process could involve several cycles of ATP hydrolysis.
51085	chaperone mediated protein folding requiring cofactor	P	The process of assisting in the correct posttranslational noncovalent assembly of proteins, which is dependent on additional protein cofactors. This process occurs over one or several cycles of nucleotide hydrolysis-dependent binding and release.
51086	chaperone mediated protein folding independent of cofactor	P	The process of assisting in the correct noncovalent assembly of posttranslational proteins and does not depend on additional protein cofactors. This function occurs over one or more cycles of nucleotide-dependent binding and release.
51087	chaperone binding	F	Interacting selectively and non-covalently with a chaperone protein, a class of proteins that bind to nascent or unfolded polypeptides and ensure correct folding or transport.
51088	PMA-inducible membrane protein ectodomain proteolysis	P	The proteolytic cleavage of transmembrane proteins and release of their ectodomain that occurs after induction by phorbol-12-myristate-13-acetate (PMA), a protein kinase C agonist.
51089	constitutive protein ectodomain proteolysis	P	The proteolytic cleavage of transmembrane proteins and release of their ectodomain that occurs constantly, regardless of environmental conditions or demands.
51090	regulation of sequence-specific DNA binding transcription factor activity	P	Any process that modulates the frequency, rate or extent of the activity of a transcription factor, any factor involved in the initiation or regulation of transcription.
51091	positive regulation of sequence-specific DNA binding transcription factor activity	P	Any process that activates or increases the frequency, rate or extent of activity of a transcription factor, any factor involved in the initiation or regulation of transcription.
51092	positive regulation of NF-kappaB transcription factor activity	P	Any process that activates or increases the frequency, rate or extent of activity of the transcription factor NF-kappaB.
51093	negative regulation of developmental process	P	Any process that stops, prevents or reduces the rate or extent of development, the biological process whose specific outcome is the progression of an organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).
51094	positive regulation of developmental process	P	Any process that activates or increases the rate or extent of development, the biological process whose specific outcome is the progression of an organism over time from an initial condition (e.g. a zygote, or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).
51095	regulation of helicase activity	P	Any process that modulates the frequency, rate or extent of helicase activity.
51096	positive regulation of helicase activity	P	Any process that activates or increases the activity of a helicase.
51097	negative regulation of helicase activity	P	Any process that stops or reduces the activity of a helicase.
51098	regulation of binding	P	Any process that modulates the frequency, rate or extent of binding, the selective interaction of a molecule with one or more specific sites on another molecule.
51099	positive regulation of binding	P	Any process that activates or increases the rate or extent of binding, the selective interaction of a molecule with one or more specific sites on another molecule.
51100	negative regulation of binding	P	Any process that stops or reduces the rate or extent of binding, the selective interaction of a molecule with one or more specific sites on another molecule.
51101	regulation of DNA binding	P	Any process that modulates the frequency, rate or extent of DNA binding. DNA binding is any process in which a gene product interacts selectively with DNA (deoxyribonucleic acid).
51102	DNA ligation involved in DNA recombination	P	The re-formation of a broken phosphodiester bond in the DNA backbone, carried out by DNA ligase, that contributes to DNA recombination.
51103	DNA ligation involved in DNA repair	P	The re-formation of a broken phosphodiester bond in the DNA backbone, carried out by DNA ligase, that contributes to DNA repair.
51104	DNA-dependent DNA replication DNA ligation	P	The re-formation of a broken phosphodiester bond in the DNA backbone, carried out by DNA ligase, that contributes to DNA-dependent DNA replication.
51105	regulation of DNA ligation	P	Any process that modulates the frequency, rate or extent of DNA ligation, the re-formation of a broken phosphodiester bond in the DNA backbone, carried out by DNA ligase.
51106	positive regulation of DNA ligation	P	Any process that activates or increases the frequency, rate or extent of DNA ligation, the re-formation of a broken phosphodiester bond in the DNA backbone, carried out by DNA ligase.
51107	negative regulation of DNA ligation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of DNA ligation, the re-formation of a broken phosphodiester bond in the DNA backbone, carried out by DNA ligase.
51108	carnitine-CoA ligase activity	F	Catalysis of the reaction: D-carnitine + CoA + ATP = AMP + diphosphate + D-carnitinyl-CoA.
51109	crotonobetaine-CoA ligase activity	F	Catalysis of the reaction: CoA + crotono-betaine + ATP = AMP + diphosphate + crotonobetainyl-CoA.
51110	peptidyl-histidine uridylylation, to form peptidyl-1'-(phospho-5'-uridine)-L-histidine	P	The uridylylation of peptidyl-histidine to form peptidyl-1'-(phospho-5'-uridine)-L-histidine (otherwise known as tau-UMP-histidine, tele-UMP-histidine).
51111	peptidyl-histidine adenylylation	P	The adenylylation of peptidyl-histidine to form peptidyl-1'-(phospho-5'-adenosine)-L-histidine (otherwise known as tau-AMP-histidine, tele-AMP-histidine) or peptidyl-3'-(phospho-5'-adenosine)-L-histidine (otherwise known as pi-AMP-histidine, pros-AMP-histidine).
51112	peptidyl-histidine adenylylation, to form peptidyl-1'-(phospho-5'-adenosine)-L-histidine	P	The adenylylation of peptidyl-histidine to form peptidyl-1'-(phospho-5'-adenosine)-L-histidine (otherwise known as tau-AMP-histidine, tele-AMP-histidine).
51113	enzyme active site formation via 1'-(phospho-5'-adenosine)-L-histidine	P	The transient adenylylation of peptidyl-histidine to form 1'-(phospho-5'-adenosine)-L-histidine (otherwise known as tau-AMP-histidine, tele-AMP-histidine).
51114	peptidyl-histidine uridylylation	P	The uridylylation of peptidyl-histidine to form peptidyl-1'-(phospho-5'-uridine)-L-histidine (otherwise known as tau-UMP-histidine, tele-UMP-histidine) or peptidyl-3'-(phospho-5'-uridine)-L-histidine (otherwise known as pi-UMP-histidine, pros-UMP-histidine).
51115	enzyme active site formation via 1'-(phospho-5'-uridine)-L-histidine	P	The transient uridylylation of peptidyl-histidine to form 1'-(phospho-5'-uridine)-L-histidine (otherwise known as tau-UMP-histidine, tele-UMP-histidine).
51116	cobaltochelatase activity	F	Catalysis of the reaction: ATP + Co(2+) + H(2)O + hydrogenobyrinate a,c-diamide = ADP + cob(II)yrinate a,c diamide + 4 H(+) + phosphate.
51117	ATPase binding	F	Interacting selectively and non-covalently with an ATPase, any enzyme that catalyzes the hydrolysis of ATP.
51118	glucan endo-1,3-alpha-glucosidase activity	F	Catalysis of the endohydrolysis of (1->3)-alpha-D-glucosidic linkages in isolichenin, pseudonigeran and nigeran.
51119	sugar transmembrane transporter activity	F	Catalysis of the transfer of a sugar from one side of the membrane to the other. A sugar is any member of a class of sweet, water-soluble, crystallizable carbohydrates, which are the monosaccharides and smaller oligosaccharides.
51120	hepoxilin A3 synthase activity	F	Catalysis of the reaction: 12S-5Z,8Z,10E,14Z-12-hydro(pero)xy-eicosa-5,8,10,14-tetraenoic acid = (5Z,9E,14Z)-(8,11R,12S)-11,12-epoxy-8-hydroxyicosa-5,9,14-trienoate. 12S-5Z,8Z,10E,14Z-12-hydro(pero)xy-eicosa-5,8,10,14-tetraenoic acid is also known as 12S-HpETE, and (5Z,9E,14Z)-(8,11R,12S)-11,12-epoxy-8-hydroxyicosa-5,9,14-trienoate as hepoxilin A3.
51121	hepoxilin metabolic process	P	The chemical reactions and pathways involving hepoxilins, a class of bioactive icosanoids with roles in the regulation of cell physiology.
51122	hepoxilin biosynthetic process	P	The chemical reactions and pathways resulting in the formation of hepoxilins, a class of bioactive icosanoids with roles in the regulation of cell physiology.
51123	RNA polymerase II transcriptional preinitiation complex assembly	P	The aggregation, arrangement and bonding together of proteins on an RNA polymerase II promoter DNA to form the transcriptional preinitiation complex (PIC), the formation of which is a prerequisite for transcription by RNA polymerase.
51124	synaptic growth at neuromuscular junction	P	The growth of a synapse at a neuromuscular junction, the site of apposition of a motor end plate and the subneural cleft of the skeletal muscle fiber that it innervates.
51125	regulation of actin nucleation	P	Any process that modulates the frequency, rate or extent of actin nucleation, the initial step in the formation of an actin filament in which actin monomers combine to form a new filament.
51126	negative regulation of actin nucleation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of actin nucleation, the initial step in the formation of an actin filament in which actin monomers combine to form a new filament.
51127	positive regulation of actin nucleation	P	Any process that activates or increases the frequency, rate or extent of actin nucleation, the initial step in the formation of an actin filament in which actin monomers combine to form a new filament.
51128	regulation of cellular component organization	P	Any process that modulates the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.
51129	negative regulation of cellular component organization	P	Any process that stops, prevents, or reduces the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.
51130	positive regulation of cellular component organization	P	Any process that activates or increases the frequency, rate or extent of a process involved in the formation, arrangement of constituent parts, or disassembly of cell structures, including the plasma membrane and any external encapsulating structures such as the cell wall and cell envelope.
51131	chaperone-mediated protein complex assembly	P	The aggregation, arrangement and bonding together of a set of components to form a protein complex, mediated by chaperone molecules that do not form part of the finished complex.
51132	NK T cell activation	P	The change in morphology and behavior of a mature or immature natural killer T cell resulting from exposure to a mitogen, cytokine, chemokine, cellular ligand, or an antigen for which it is specific.
51133	regulation of NK T cell activation	P	Any process that modulates the frequency, rate or extent of natural killer T cell activation.
51134	negative regulation of NK T cell activation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer T cell activation.
51135	positive regulation of NK T cell activation	P	Any process that activates or increases the frequency, rate or extent of natural killer T cell activation.
51136	regulation of NK T cell differentiation	P	Any process that modulates the frequency, rate or extent of natural killer T cell differentiation.
51137	negative regulation of NK T cell differentiation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer T cell differentiation.
51138	positive regulation of NK T cell differentiation	P	Any process that activates or increases the frequency, rate or extent of natural killer T cell differentiation.
51139	metal ion:proton antiporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: metal ion(in) + H+(out) = metal ion(out) + H+(in).
51140	regulation of NK T cell proliferation	P	Any process that modulates the frequency, rate or extent of natural killer T cell proliferation.
51141	negative regulation of NK T cell proliferation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer T cell proliferation.
51142	positive regulation of NK T cell proliferation	P	Any process that activates or increases the frequency, rate or extent of natural killer T cell proliferation.
51143	propanediol metabolic process	P	The chemical reactions and pathways involving propanediol, CH3-CHOH-CH2OH, a sweet, colorless, viscous, hygroscopic liquid used as an antifreeze, in brake fluid and as a humectant in cosmetics and personal care items.
51144	propanediol catabolic process	P	The chemical reactions and pathways resulting in the breakdown of propanediol, a sweet, colorless, viscous, hygroscopic liquid with the formula CH3-CHOH-CH2OH.
51145	smooth muscle cell differentiation	P	The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell; smooth muscle lacks transverse striations in its constituent fibers and are almost always involuntary.
51146	striated muscle cell differentiation	P	The process in which a relatively unspecialized cell acquires specialized features of a striated muscle cell; striated muscle fibers are divided by transverse bands into striations, and cardiac and voluntary muscle are types of striated muscle.
51147	regulation of muscle cell differentiation	P	Any process that modulates the frequency, rate or extent of muscle cell differentiation.
51148	negative regulation of muscle cell differentiation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of muscle cell differentiation.
51149	positive regulation of muscle cell differentiation	P	Any process that activates or increases the frequency, rate or extent of muscle cell differentiation.
51150	regulation of smooth muscle cell differentiation	P	Any process that modulates the frequency, rate or extent of smooth muscle cell differentiation.
51151	negative regulation of smooth muscle cell differentiation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of smooth muscle cell differentiation.
51152	positive regulation of smooth muscle cell differentiation	P	Any process that activates or increases the frequency, rate or extent of smooth muscle cell differentiation.
51153	regulation of striated muscle cell differentiation	P	Any process that modulates the frequency, rate or extent of striated muscle cell differentiation.
51154	negative regulation of striated muscle cell differentiation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of striated muscle cell differentiation.
51155	positive regulation of striated muscle cell differentiation	P	Any process that activates or increases the frequency, rate or extent of striated muscle cell differentiation.
51156	glucose 6-phosphate metabolic process	P	The chemical reactions and pathways involving glucose 6-phosphate, a monophosphorylated derivative of glucose with the phosphate group attached to C-6.
51157	arabitol catabolic process	P	The chemical reactions and pathways resulting in the breakdown of arabitol, the pentitol derived from arabinose or lyxose by reduction of the aldehyde group.
51158	L-arabitol catabolic process	P	The chemical reactions and pathways resulting in the breakdown of L-arabitol, the pentitol derived from arabinose or lyxose by reduction of the aldehyde group.
51159	D-arabitol catabolic process	P	The chemical reactions and pathways resulting in the breakdown of D-arabitol, the pentitol derived from arabinose or lyxose by reduction of the aldehyde group. The D enantiomer is present in lichens and mushrooms.
51160	L-xylitol catabolic process	P	The chemical reactions and pathways resulting in the breakdown of L-xylitol, a five-carbon sugar alcohol derived from xylose by reduction of the carbonyl group.
51161	arabitol metabolic process	P	The chemical reactions and pathways involving arabitol, the pentitol derived from arabinose or lyxose by reduction of the aldehyde group.
51162	L-arabitol metabolic process	P	The chemical reactions and pathways involving L-arabitol, the pentitol derived from arabinose or lyxose by reduction of the aldehyde group.
51163	D-arabitol metabolic process	P	The chemical reactions and pathways involving D-arabitol, the pentitol derived from arabinose or lyxose by reduction of the aldehyde group. The D enantiomer is present in lichens and mushrooms.
51164	L-xylitol metabolic process	P	The chemical reactions and pathways involving L-xylitol, a five-carbon sugar alcohol derived from xylose by reduction of the carbonyl group. It is as sweet as sucrose and is used as a noncariogenic sweetner and as a sugar substitute in diabetic diets.
51165	2,5-dihydroxypyridine metabolic process	P	The chemical reactions and pathways involving 2,5-dihydroxypyridine.
51166	2,5-dihydroxypyridine catabolic process	P	The chemical reactions and pathways resulting in the breakdown of 2,5-dihydroxypyridine.
51167	xylulose 5-phosphate metabolic process	P	The chemical reactions and pathways involving xylulose 5-phosphate, a derivative of the ketopentose xylulose phosphorylated at the 5 carbon; it is an intermediate in the pentose phosphate pathway.
51168	nuclear export	P	The directed movement of substances out of the nucleus.
51169	nuclear transport	P	The directed movement of substances into, out of, or within the nucleus.
51170	nuclear import	P	The directed movement of substances into the nucleus.
51171	regulation of nitrogen compound metabolic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nitrogen or nitrogenous compounds.
51172	negative regulation of nitrogen compound metabolic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving nitrogen or nitrogenous compounds.
51173	positive regulation of nitrogen compound metabolic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving nitrogen or nitrogenous compounds.
51174	regulation of phosphorus metabolic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving phosphorus or compounds containing phosphorus.
51175	negative regulation of sulfur metabolic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving sulfur or compounds containing sulfur.
51176	positive regulation of sulfur metabolic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving sulfur or compounds containing sulfur.
51177	meiotic sister chromatid cohesion	P	The cell cycle process in which sister chromatids of a replicated chromosome are joined along the entire length of the chromosome during meiosis.
51178	meiotic chromosome decondensation	P	The cell cycle process in which chromosome structure is altered from the condensed form held during meiosis to the relaxed dispersed form held in resting cells.
51179	localization	P	Any process in which a cell, a substance, or a cellular entity, such as a protein complex or organelle, is transported, tethered to or otherwise maintained in a specific location. In the case of substances, localization may also be achieved via selective degradation.
51180	vitamin transport	P	The directed movement of vitamins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A vitamin is one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body.
51181	cofactor transport	P	The directed movement of a cofactor into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A cofactor is a substance that is required for the activity of an enzyme or other protein.
51182	coenzyme transport	P	The directed movement of a coenzyme into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A coenzyme is any of various nonprotein organic cofactors that are required, in addition to an enzyme and a substrate, for an enzymatic reaction to proceed.
51183	vitamin transporter activity	F	Enables the directed movement of vitamins into, out of or within a cell, or between cells. A vitamin is one of a number of unrelated organic substances that occur in many foods in small amounts and that are necessary in trace amounts for the normal metabolic functioning of the body.
51184	cofactor transporter activity	F	Enables the directed movement of a cofactor into, out of or within a cell, or between cells. A cofactor is a substance that is required for the activity of an enzyme or other protein.
51185	coenzyme transporter activity	F	Enables the directed movement of a coenzyme into, out of or within a cell, or between cells. A coenzyme is any of various nonprotein organic cofactors that are required, in addition to an enzyme and a substrate, for an enzymatic reaction to proceed.
51186	cofactor metabolic process	P	The chemical reactions and pathways involving a cofactor, a substance that is required for the activity of an enzyme or other protein. Cofactors may be inorganic, such as the metal atoms zinc, iron, and copper in certain forms, or organic, in which case they are referred to as coenzymes. Cofactors may either be bound tightly to active sites or bind loosely with the substrate.
51187	cofactor catabolic process	P	The chemical reactions and pathways resulting in the breakdown of a cofactor, a substance that is required for the activity of an enzyme or other protein.
51188	cofactor biosynthetic process	P	The chemical reactions and pathways resulting in the formation of a cofactor, a substance that is required for the activity of an enzyme or other protein.
51189	prosthetic group metabolic process	P	The chemical reactions and pathways involving a prosthetic group, the non-amino acid portion of certain protein molecules. Prosthetic groups may be inorganic or organic and are usually required for the biological activity of the protein.
51190	prosthetic group catabolic process	P	The chemical reactions and pathways resulting in the breakdown of a prosthetic group, the non-amino acid portion of certain protein molecules. Prosthetic groups may be inorganic or organic and are usually required for the biological activity of the protein.
51191	prosthetic group biosynthetic process	P	The chemical reactions and pathways resulting in the formation of a prosthetic group, the non-amino acid portion of certain protein molecules. Prosthetic groups may be inorganic or organic and are usually required for the biological activity of the protein.
51192	prosthetic group binding	F	Interacting selectively and non-covalently with a prosthetic group, the non-amino acid portion of certain protein molecules. Prosthetic groups may be inorganic or organic and are usually required for the biological activity of the protein.
51193	regulation of cofactor metabolic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a cofactor.
51194	positive regulation of cofactor metabolic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving a cofactor.
51195	negative regulation of cofactor metabolic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving a cofactor.
51196	regulation of coenzyme metabolic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a coenzyme.
51197	positive regulation of coenzyme metabolic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving a coenzyme.
51198	negative regulation of coenzyme metabolic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving a coenzyme.
51199	regulation of prosthetic group metabolic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a prosthetic group.
51200	positive regulation of prosthetic group metabolic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving a prosthetic group.
51201	negative regulation of prosthetic group metabolic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving a prosthetic group.
51202	phytochromobilin metabolic process	P	The chemical reactions and pathways involving phytochromobilin, the linear tetrapyrrole chromophore required for plant phytochrome photoactivity.
51203	peptidyl-aspartic acid reduction to form L-aspartyl aldehyde	P	The reduction of peptidyl-aspartic acid to form peptidyl-L-aspartyl aldehyde, as found photosystem II P680 chlorophyll A apoprotein.
51204	protein insertion into mitochondrial membrane	P	The process that results in the incorporation of a protein into a mitochondrial membrane.
51205	protein insertion into membrane	P	The process that results in the incorporation of a protein into a biological membrane. Incorporation in this context means having some part or covalently attached group that is inserted into the the hydrophobic region of one or both bilayers.
51206	silicate metabolic process	P	The chemical reactions and pathways involving silicates, the salts of silicic acids. Silicates are usually composed of silicon and oxygen (Si[x]O[y]), one or more metals, and possibly hydrogen. Types of silicate include unisilicates, metasilicates and hydrous silicates.
51208	sequestering of calcium ion	P	The process of binding or confining calcium ions such that they are separated from other components of a biological system.
51209	release of sequestered calcium ion into cytosol	P	The process in which calcium ions sequestered in the endoplasmic reticulum, Golgi apparatus or mitochondria are released into the cytosolic compartment.
51210	isotropic cell growth	P	The process in which a cell irreversibly increases in size uniformly in all directions. In general, a rounded cell morphology reflects isotropic cell growth.
51211	anisotropic cell growth	P	The process in which a cell irreversibly increases in size in one or more axes, where the growth rate varies according to the direction of growth. Growth may be limited to a particular axis, axes, or to particular locations on the surface of the cell.
51212	vanadium ion binding	F	Interacting selectively and non-covalently with vanadium (V) ions.
51213	dioxygenase activity	F	Catalysis of an oxidation-reduction (redox) reaction in which both atoms of oxygen from one molecule of O2 are incorporated into the (reduced) product(s) of the reaction. The two atoms of oxygen may be distributed between two different products.
51214	RNA virus induced gene silencing	P	Gene silencing induced by RNA viruses leading to a sequence-specific degradation of target mRNAs or post-transcriptional gene silencing.
51215	DNA virus induced gene silencing	P	Gene silencing induced by DNA viruses leading to a sequence-specific degradation of target mRNAs or post-transcriptional gene silencing.
51216	cartilage development	P	The process whose specific outcome is the progression of a cartilage element over time, from its formation to the mature structure. Cartilage elements are skeletal elements that consist of connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate.
51217	molybdenum incorporation via L-aspartyl molybdenum bis(molybdopterin guanine dinucleotide)	P	The incorporation of molybdenum into a protein via L-aspartyl molybdenum bis(molybdopterin guanine dinucleotide).
51218	tungsten incorporation via L-selenocysteinyl tungsten bis(molybdopterin guanine dinucleotide)	P	The incorporation of tungsten into a protein via L-selenocysteinyl tungsten bis(molybdopterin guanine dinucleotide).
51219	phosphoprotein binding	F	Interacting selectively and non-covalently with a phosphorylated protein.
51220	cytoplasmic sequestering of protein	P	The selective interaction of a protein with specific molecules in the cytoplasm, thereby inhibiting its transport into other areas of the cell.
51221	tungsten incorporation into metallo-sulfur cluster	P	The incorporation of tungsten into a metallo-sulfur cluster.
51222	positive regulation of protein transport	P	Any process that activates or increases the frequency, rate or extent of the directed movement of a protein into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
51223	regulation of protein transport	P	Any process that modulates the frequency, rate or extent of the directed movement of a protein into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
51224	negative regulation of protein transport	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a protein into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
51225	spindle assembly	P	The aggregation, arrangement and bonding together of a set of components to form the spindle, the array of microtubules and associated molecules that serves to move duplicated chromosomes apart.
51228	mitotic spindle disassembly	P	The controlled breakdown of the spindle during a mitotic cell cycle.
51229	meiotic spindle disassembly	P	The controlled breakdown of the spindle during a meiotic cell cycle.
51230	spindle disassembly	P	The controlled breakdown of the spindle, the array of microtubules and associated molecules that serves to move duplicated chromosomes apart.
51231	spindle elongation	P	The cell cycle process in which the distance is lengthened between poles of the spindle.
51232	meiotic spindle elongation	P	The lengthening of the distance between poles of the spindle during a meiotic cell cycle.
51233	spindle midzone	C	The area in the center of the spindle where the spindle microtubules from opposite poles overlap.
51234	establishment of localization	P	Any process that localizes a substance or cellular component. This may occur via movement, tethering or selective degradation.
51235	maintenance of location	P	Any process in which a cell, substance or cellular entity, such as a protein complex or organelle, is maintained in a location and prevented from moving elsewhere.
51236	establishment of RNA localization	P	The directed movement of RNA to a specific location.
51237	maintenance of RNA location	P	Any process in which RNA is maintained in a location and prevented from moving elsewhere.
51238	sequestering of metal ion	P	The process of binding or confining metal ions such that they are separated from other components of a biological system.
51239	regulation of multicellular organismal process	P	Any process that modulates the frequency, rate or extent of a multicellular organismal process, the processes pertinent to the function of a multicellular organism above the cellular level; includes the integrated processes of tissues and organs.
51240	positive regulation of multicellular organismal process	P	Any process that activates or increases the frequency, rate or extent of an organismal process, any of the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs.
51241	negative regulation of multicellular organismal process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of an organismal process, the processes pertinent to the function of an organism above the cellular level; includes the integrated processes of tissues and organs.
51245	negative regulation of cellular defense response	P	Any process that stops, prevents, or reduces the rate of the cellular defense response.
51246	regulation of protein metabolic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a protein.
51247	positive regulation of protein metabolic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving a protein.
51248	negative regulation of protein metabolic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of chemical reactions and pathways involving a protein.
51249	regulation of lymphocyte activation	P	Any process that modulates the frequency, rate or extent of lymphocyte activation.
51250	negative regulation of lymphocyte activation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of lymphocyte activation.
51251	positive regulation of lymphocyte activation	P	Any process that activates or increases the frequency, rate or extent of lymphocyte activation.
51252	regulation of RNA metabolic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving RNA.
51253	negative regulation of RNA metabolic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving RNA.
51254	positive regulation of RNA metabolic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving RNA.
51255	spindle midzone assembly	P	The cell cycle process in which aggregation, arrangement and bonding together of a set of components to form the spindle midzone. The spindle midzone is the area in the center of the spindle where the spindle microtubules from opposite poles overlap.
51256	mitotic spindle midzone assembly	P	The cell cycle process in which the aggregation, arrangement and bonding together of a set of components forms the spindle midzone.
51257	meiotic spindle midzone assembly	P	The formation of the spindle midzone, the area in the center of the spindle where the spindle microtubules from opposite poles overlap, as a part of the process of meiosis.
51258	protein polymerization	P	The process of creating protein polymers, compounds composed of a large number of component monomers; polymeric proteins may be made up of different or identical monomers. Polymerization occurs by the addition of extra monomers to an existing poly- or oligomeric protein.
51259	protein oligomerization	P	The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of component monomers; protein oligomers may be composed of different or identical monomers. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer.
51260	protein homooligomerization	P	The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of identical component monomers. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer.
51261	protein depolymerization	P	The process in which protein polymers, compounds composed of a large number of component monomers, are broken down. Depolymerization occurs by the successive removal of monomers from an existing poly- or oligomeric protein.
51262	protein tetramerization	P	The formation of a protein tetramer, a macromolecular structure consisting of four noncovalently associated identical or nonidentical subunits.
51263	microcin E492 biosynthetic process by siderophore ester modification of peptidyl-serine	P	The modification of serine to N-[5-(6-O-seryl-beta-glucosyl)-2,3-dihydroxybenzoyl]-O-[N-(2,3-dihydroxybenzoyl)-O-[N-(2,3-dihydroxybenzoyl)seryl]seryl]serine as found in microcin E492 produced from the mceA gene in plasmid pJAM229 of the E. coli VCS257 strain and the K. pneumoniae RYC492 strain.
51264	mono-olein transacylation activity	F	Catalysis of the reaction: mono-olein + mono-olein = diolein + glycerol. Mono-olein, also known as mono-oleoylglycerol, is the monoglyceride formed from oleic acid, 9-octodecenoic acid; diolein is also known as dioleoylglycerol.
51265	diolein transacylation activity	F	Catalysis of the reaction: diolein + mono-olein = triolein + glycerol. Mono-olein, also known as mono-oleoylglycerol, is the monoglyceride formed from oleic acid, 9-octodecenoic acid; diolein is also known as dioleoylglycerol, and triolein as trioleoylglycerol and olein.
51266	sirohydrochlorin ferrochelatase activity	F	Catalysis of the reaction: siroheme + 2 H+ = Fe(2+) + sirohydrochlorin.
51267	CP2 mannose-ethanolamine phosphotransferase activity	F	Catalysis of the reaction: ethanolamine phosphate + Man-alpha-(1,2)-Man-alpha-(1,2)-Man-alpha-(1,6)-R = Man-alpha-(1,2)-Man-alpha-6-P-EtN-(1,2)-Man-alpha-(1,6)-R; R is Man-alpha(1,4)-GlcNH2-inositol-PO4-lipid. This reaction is the transfer of ethanolamine phosphate to C6 of second mannose in the GPI lipid precursor CP2.
51268	alpha-keto amide reductase activity	F	Catalysis of the reaction: alpha-keto amide + 2 H+ (from donor) = (R)-hydroxy amide. Alpha-keto amides are of the form R-CO-CONH2, where R may be aromatic or aliphatic.
51269	alpha-keto ester reductase activity	F	Catalysis of the reaction: alpha-keto ester + 2 H+ (from donor) = (R)-hydroxy ester. Alpha-keto esters are of the form R(1)-CO-CO-O-R(2), where the R groups may be aromatic or aliphatic.
51270	regulation of cellular component movement	P	Any process that modulates the frequency, rate or extent of the movement of a cellular component.
51271	negative regulation of cellular component movement	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the movement of a cellular component.
51272	positive regulation of cellular component movement	P	Any process that activates or increases the frequency, rate or extent of the movement of a cellular component.
51273	beta-glucan metabolic process	P	The chemical reactions and pathways involving beta-glucans, compounds composed of glucose residues linked by beta-D-glucosidic bonds.
51274	beta-glucan biosynthetic process	P	The chemical reactions and pathways resulting in the formation of beta-glucans.
51275	beta-glucan catabolic process	P	The chemical reactions and pathways resulting in the breakdown of beta-glucans.
51276	chromosome organization	P	A process that is carried out at the cellular level that results in the assembly, arrangement of constituent parts, or disassembly of chromosomes, structures composed of a very long molecule of DNA and associated proteins that carries hereditary information. This term covers covalent modifications at the molecular level as well as spatial relationships among the major components of a chromosome.
51278	fungal-type cell wall polysaccharide biosynthetic process	P	The chemical reactions and pathways resulting in the formation of the polysaccharides which make up the fungal-type cell wall.
51279	regulation of release of sequestered calcium ion into cytosol	P	Any process that modulates the frequency, rate or extent of the release into the cytosolic compartment of calcium ions sequestered in the endoplasmic reticulum or mitochondria.
51280	negative regulation of release of sequestered calcium ion into cytosol	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the release into the cytosolic compartment of calcium ions sequestered in the endoplasmic reticulum or mitochondria.
51281	positive regulation of release of sequestered calcium ion into cytosol	P	Any process that activates or increases the frequency, rate or extent of the release into the cytosolic compartment of calcium ions sequestered in the endoplasmic reticulum or mitochondria.
51282	regulation of sequestering of calcium ion	P	Any process that modulates the frequency, rate or extent of the binding or confining calcium ions such that they are separated from other components of a biological system.
51283	negative regulation of sequestering of calcium ion	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the binding or confining calcium ions such that they are separated from other components of a biological system.
51284	positive regulation of sequestering of calcium ion	P	Any process that activates or increases the frequency, rate or extent of the binding or confining calcium ions such that they are separated from other components of a biological system.
51285	cell cortex of cell tip	C	The region directly beneath the plasma membrane at the cell tip. The cell tip is the region at either end of the longest axis of a cylindrical or elongated cell.
51286	cell tip	C	The region at the end of the longest axis of a cylindrical or elongated cell.
51287	NAD binding	F	Interacting selectively and non-covalently with nicotinamide adenine dinucleotide, a coenzyme involved in many redox and biosynthetic reactions; binding may be to either the oxidized form, NAD+, or the reduced form, NADH.
51289	protein homotetramerization	P	The formation of a protein homotetramer, a macromolecular structure consisting of four noncovalently associated identical subunits.
51290	protein heterotetramerization	P	The formation of a protein heterotetramer, a macromolecular structure consisting of four noncovalently associated subunits, of which not all are identical.
51291	protein heterooligomerization	P	The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of component monomers that are not all identical. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer.
51292	nuclear pore complex assembly	P	The aggregation, arrangement and bonding together of a set of components to form a nuclear pore complex.
51293	establishment of spindle localization	P	The directed movement of the spindle to a specific location in the cell.
51294	establishment of spindle orientation	P	Any process that set the alignment of spindle relative to other cellular structures.
51295	establishment of meiotic spindle localization	P	The cell cycle process in which the directed movement of the meiotic spindle to a specific location in the cell occurs.
51296	establishment of meiotic spindle orientation	P	Any process that set the alignment of meiotic spindle relative to other cellular structures.
51297	centrosome organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a centrosome, a structure comprised of a pair of centrioles and peri-centriolar material from which a microtubule spindle apparatus is organized.
51298	centrosome duplication	P	The replication of a centrosome, a structure comprised of a pair of centrioles and peri-centriolar material from which a microtubule spindle apparatus is organized.
51299	centrosome separation	P	The process in which duplicated centrosome components move away from each other. The centriole pair within each centrosome becomes part of a separate microtubule organizing center that nucleates a radial array of microtubules called an aster. The two asters move to opposite sides of the nucleus to form the two poles of the mitotic spindle.
51300	spindle pole body organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the spindle pole body (SPB). The SPB is the microtubule organizing center in fungi, and is functionally homologous to the animal cell centrosome.
51301	cell division	P	The process resulting in division and partitioning of components of a cell to form more cells; may or may not be accompanied by the physical separation of a cell into distinct, individually membrane-bounded daughter cells.
51302	regulation of cell division	P	Any process that modulates the frequency, rate or extent of the physical partitioning and separation of a cell into daughter cells.
51303	establishment of chromosome localization	P	The directed movement of a chromosome to a specific location.
51304	chromosome separation	P	The cell cycle process in which paired chromosomes are detached from each other. Chromosome separation begins with the release of cohesin complexes from chromosomes; in budding yeast, this includes the cleavage of cohesin complexes along the chromosome arms, followed by the separation of the centromeric regions. Chromosome separation also includes formation of chromatid axes mediated by condensins, and ends with the disentangling of inter-sister catenation catalyzed by topoisomerase II (topo II).
51305	chromosome movement towards spindle pole	P	The directed movement of chromosomes in the center of the spindle towards the spindle poles, mediated by the shortening of microtubules attached to the chromosomes.
51306	mitotic sister chromatid separation	P	The process in which sister chromatids are physically detached from each other during mitosis.
51307	meiotic chromosome separation	P	The process in which chromosomes are physically detached from each other during meiosis.
51308	male meiosis chromosome separation	P	The process in which paired chromosomes are physically detached from each other during male meiosis.
51309	female meiosis chromosome separation	P	The process in which paired chromosomes are physically detached from each other during female meiosis.
51310	metaphase plate congression	P	The alignment of chromosomes at the metaphase plate (spindle equator), a plane halfway between the poles of the spindle.
51311	meiotic metaphase plate congression	P	The cell cycle process in which chromosomes are aligned at the metaphase plate, a plane halfway between the poles of the meiotic spindle, during meiosis.
51312	chromosome decondensation	P	The alteration of chromosome structure from the condensed form to a relaxed disperse form.
51315	attachment of mitotic spindle microtubules to kinetochore	P	The cell cycle process in which spindle microtubules become physically associated with the proteins making up the kinetochore complex as part of mitotic metaphase plate congression.
51316	attachment of spindle microtubules to kinetochore involved in meiotic chromosome segregation	P	The cell cycle process in which spindle microtubules become physically associated with the proteins making up the kinetochore complex contributing to meiotic chromosome segregation.
51318	G1 phase	P	The cell cycle 'gap' phase which is the interval between the completion of DNA segregation (usually by mitosis or meiosis) and the beginning of DNA synthesis.
51319	G2 phase	P	The cell cycle 'gap' phase which is the interval between the completion of DNA synthesis and the beginning of DNA segregation (usually by mitosis or meiosis).
51320	S phase	P	The cell cycle phase, following G1, during which DNA synthesis takes place.
51321	meiotic cell cycle	P	Progression through the phases of the meiotic cell cycle, in which canonically a cell replicates to produce four offspring with half the chromosomal content of the progenitor cell via two nuclear divisions.
51322	anaphase	P	The cell cycle phase, following metaphase, during which the chromosomes separate and migrate towards the poles of the spindle.
51323	metaphase	P	The cell cycle phase, following prophase or prometaphase in higher eukaryotes, during which chromosomes become aligned on the equatorial plate of the cell.
51324	prophase	P	The cell cycle phase which is the first stage of M phase of meiosis and mitosis and during which chromosomes condense and the two daughter centrioles and their asters migrate toward the poles of the cell.
51325	interphase	P	The cell cycle phase following cytokinesis which begins with G1 phase, proceeds through S phase and G2 phase and ends when prophase of meiosis or mitosis begins. During interphase the cell readies itself for meiosis or mitosis and the replication of its DNA occurs.
51326	telophase	P	The cell cycle phase which follows anaphase during M phase of mitosis and meiosis and during which the chromosomes arrive at the poles of the cell and the division of the cytoplasm starts.
51327	meiotic M phase	P	A cell cycle phase during which nuclear division occurs, and which is comprises the phases: prophase, metaphase, anaphase and telophase and occurs as part of a meiotic cell cycle.
51328	meiotic interphase	P	The cell cycle phase which begins after cytokinesis and ends when meiotic prophase begins. Meiotic cells have an interphase after each meiotic division, but only interphase I involves replication of the cell's DNA.
51329	mitotic interphase	P	The cell cycle phase following cytokinesis which begins with G1 phase, proceeds through S phase and G2 phase and ends when mitotic prophase begins. During interphase the cell readies itself for mitosis and the replication of its DNA occurs.
51330	meiotic G1 phase	P	The cell cycle 'gap' phase which is the interval between the completion of DNA segregation by meiosis and the beginning of DNA synthesis.
51331	meiotic G2 phase	P	The cell cycle 'gap' phase which is the interval between the completion of DNA synthesis and the beginning of DNA segregation by meiosis.
51332	meiotic S phase	P	The cell cycle phase, following G1, during which DNA synthesis takes place as part of a meiotic cell cycle.
51333	meiotic nuclear envelope reassembly	P	The cell cycle process in which the reformation of the nuclear envelope during meiosis occurs.
51334	meiosis I nuclear envelope reassembly	P	The reformation of the nuclear envelope during meiosis I.
51335	meiosis II nuclear envelope reassembly	P	The reformation of the nuclear envelope during meiosis II.
51336	regulation of hydrolase activity	P	Any process that modulates the frequency, rate or extent of hydrolase activity, the catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc. Hydrolase is the systematic name for any enzyme of EC class 3.
51337	amitosis	P	Nuclear division that occurs by simple constriction of the nucleus without chromosome condensation or spindle formation.
51338	regulation of transferase activity	P	Any process that modulates the frequency, rate or extent of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor). Transferase is the systematic name for any enzyme of EC class 2.
51339	regulation of lyase activity	P	Any process that modulates the frequency, rate or extent of lyase activity, the catalysis of the cleavage of C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond. They differ from other enzymes in that two substrates are involved in one reaction direction, but only one in the other direction. When acting on the single substrate, a molecule is eliminated and this generates either a new double bond or a new ring.
51340	regulation of ligase activity	P	Any process that modulates the frequency, rate or extent of ligase activity, the catalysis of the ligation of two substances with concomitant breaking of a diphosphate linkage, usually in a nucleoside triphosphate. Ligase is the systematic name for any enzyme of EC class 6.
51341	regulation of oxidoreductase activity	P	Any process that modulates the frequency, rate or extent of oxidoreductase activity, the catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.
51342	regulation of cyclic-nucleotide phosphodiesterase activity	P	Any process that modulates the frequency, rate or extent of cyclic nucleotide phosphodiesterase activity, the catalysis of the reaction: nucleotide 3',5'-cyclic phosphate + H2O = nucleotide 5'-phosphate.
51343	positive regulation of cyclic-nucleotide phosphodiesterase activity	P	Any process that activates or increases the frequency, rate or extent of cyclic nucleotide phosphodiesterase activity, the catalysis of the reaction: nucleotide 3',5'-cyclic phosphate + H2O = nucleotide 5'-phosphate.
51344	negative regulation of cyclic-nucleotide phosphodiesterase activity	P	Any process that stops or reduces the rate of cyclic nucleotide phosphodiesterase activity, the catalysis of the reaction: nucleotide 3',5'-cyclic phosphate + H2O = nucleotide 5'-phosphate.
51345	positive regulation of hydrolase activity	P	Any process that activates or increases the frequency, rate or extent of hydrolase activity, the catalysis of the hydrolysis of various bonds.
51346	negative regulation of hydrolase activity	P	Any process that stops or reduces the rate of hydrolase activity, the catalysis of the hydrolysis of various bonds.
51347	positive regulation of transferase activity	P	Any process that activates or increases the frequency, rate or extent of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from a donor compound to an acceptor.
51348	negative regulation of transferase activity	P	Any process that stops or reduces the rate of transferase activity, the catalysis of the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from a donor compound to an acceptor.
51349	positive regulation of lyase activity	P	Any process that activates or increases the frequency, rate or extent of lyase activity, the catalysis of the cleavage of C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond.
51350	negative regulation of lyase activity	P	Any process that stops or reduces the rate of lyase activity, the catalysis of the cleavage of C-C, C-O, C-N and other bonds by other means than by hydrolysis or oxidation, or conversely adding a group to a double bond.
51351	positive regulation of ligase activity	P	Any process that activates or increases the frequency, rate or extent of ligase activity, the catalysis of the ligation of two substances with concomitant breaking of a diphosphate linkage, usually in a nucleoside triphosphate.
51352	negative regulation of ligase activity	P	Any process that stops or reduces the rate of ligase activity, the catalysis of the ligation of two substances with concomitant breaking of a diphosphate linkage, usually in a nucleoside triphosphate.
51353	positive regulation of oxidoreductase activity	P	Any process that activates or increases the frequency, rate or extent of oxidoreductase activity, the catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered.
51354	negative regulation of oxidoreductase activity	P	Any process that stops or reduces the rate of oxidoreductase activity, the catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered.
51355	proprioception involved in equilibrioception	P	The series of events contributing to equilibrioception by which an organism senses the position, location, orientation, and movement of the body and its parts. Proprioception plays an important role in the ability of an organism to perceive its orientation with respect to gravity.
51356	visual perception involved in equilibrioception	P	The series of events during equilibrioception required for an organism to receive a visual stimulus, convert it to a molecular signal, and recognize and characterize the signal. Visual input plays an important role in the ability of an organism to perceive its orientation with respect to gravity.
51357	peptide cross-linking via 3-(2-methylthio)ethyl-6-(4-hydroxybenzylidene)-5-iminopiperazin-2-one	P	The formation of a 2-keto-5-iminopiperazine protein chromophore cross-link from the alpha-amino nitrogen of residue n, a methionine, to the alpha-carboxyl carbon of residue n+1, a tyrosine, and a dehydration to form a double bond to the alpha-amino nitrogen of residue n+2. This cross-linking is coupled with a dehydrogenation of residue n+1 to form a double bond between the alpha and beta carbons.
51358	peptide cross-linking via 2-imino-glutamic acid 5-imidazolinone glycine	P	The formation of the non-fluorescent protein chromophore cross-link from the alpha-carboxyl carbon of residue n, a glutamic acid, to the alpha-amino nitrogen of residue n+2, a glycine, and a dehydration to form a double bond to the alpha-amino nitrogen of residue n+1. This cross-linking is coupled with a dehydrogenation of residue n+1 to form a double bond between the alpha and beta carbons. This modification is found in the GFP-like non-fluorescent red chromoprotein from the sea anemone Radianthus macrodactylus.
51359	peptide cross-linking via 2-imino-methionine 5-imidazolinone glycine	P	The formation of the fluorescent protein FP611 chromophore cross-link from the alpha-carboxyl carbon of residue n, a methionine, to the alpha-amino nitrogen of residue n+2, a glycine, and a dehydration to form a double bond to the alpha-amino nitrogen of residue n+1. This cross-linking is coupled with a dehydrogenation of residue n+1 to form a double bond between the alpha and beta carbons. This modification is found in the GFP-like fluorescent chromoprotein from the sea anemone Entacmaea quadricolor.
51360	peptide cross-linking via L-asparagine 5-imidazolinone glycine	P	The formation of the fluorescent protein FP506 chromophore cross-link from the alpha-carboxyl carbon of residue n, an asparagine, to the alpha-amino nitrogen of residue n+2, a glycine, and a dehydration to form a double bond to the alpha-amino nitrogen of residue n+1. This cross-linking is coupled with a dehydrogenation of residue n+1 to form a double bond between the alpha and beta carbons.
51361	peptide cross-linking via L-lysine 5-imidazolinone glycine	P	The formation of a fluorescent protein chromophore cross-link from the alpha-carboxyl carbon of residue n, a lysine, to the alpha-amino nitrogen of residue n+2, a glycine, and a dehydration to form a double bond to the alpha-amino nitrogen of residue n+1. This cross-linking is coupled with a dehydrogenation of residue n+1 to form a double bond between the alpha and beta carbons.
51362	peptide cross-linking via 2-tetrahydropyridinyl-5-imidazolinone glycine	P	The formation of a 2-tetrahydropyridinyl-5-imidazolinone protein chromophore cross-link from the alpha-carboxyl carbon of residue n, a lysine, to the alpha-amino nitrogen of residue n+2, a glycine, and a dehydration to form a double bond to the alpha-amino nitrogen of residue n+1. This cross-linking is coupled with a dehydrogenation of residue n+1 to form a double bond between the alpha and beta carbons. In addition, the residue N lysine undergoes cyclization. The alpha-amino nitrogen is replaced by the epsilon-amino nitrogen, the peptide chain is broken, residue N-1 is released as an amide, and a double bond is formed between the alpha-carbon and the nitrogen so that a tetrahydropyridine ring results. This modification is found in the GFP-like fluorescent chromoprotein FP538 from the sea anemone Zoanthus species.
51363	peptidoglycan-protein cross-linking via L-alanyl-pentaglycyl-murein	P	The process of linking a protein to peptidoglycan via a carboxy terminal alanine carboxyl group through a pentaglycyl peptide to the lysine or diaminopimelic acid of the peptidoglycan.
51364	N-terminal peptidyl-proline N-formylation	P	The formylation of the N-terminal proline of proteins to form the derivative N-formylproline.
51365	cellular response to potassium ion starvation	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of potassium ions.
51366	protein decanoylation	P	The modification of a protein amino acid by formation of an ester or amide with decanoic acid.
51367	peptidyl-serine decanoylation	P	The decanoylation of peptidyl-serine to form peptidyl-O3-decanoyl-L-serine, typical of the protein ghrelin.
51368	peptidyl-threonine octanoylation	P	The octanoylation of peptidyl-threonine to form peptidyl-O3-octanoyl-L-threonine, typical of the protein ghrelin.
51369	peptidyl-threonine decanoylation	P	The decanoylation of peptidyl-threonine to form peptidyl-O3-decanoyl-L-threonine, typical of the protein ghrelin.
51371	muscle alpha-actinin binding	F	Interacting selectively and non-covalently with muscle isoforms of actinin. Muscle alpha-actinin isoforms are found in skeletal and cardiac muscle and are localized to the Z-disc.
51373	FATZ binding	F	Interacting selectively and non-covalently with a member of the FATZ family of proteins, filamin-, actinin-, and telethonin-binding proteins of the Z-disc of striated muscle. FATZ proteins are located in the Z-disc of the sarcomere and are involved in a complex network of interactions with other Z-band components.
51377	mannose-ethanolamine phosphotransferase activity	F	Catalysis of the transfer of ethanolamine phosphate to a mannose residue in the GPI lipid precursor.
51378	serotonin binding	F	Interacting selectively and non-covalently with serotonin (5-hydroxytryptamine), a monoamine neurotransmitter occurring in the peripheral and central nervous systems, also having hormonal properties.
51379	epinephrine binding	F	Interacting selectively and non-covalently with epinephrine, a hormone produced by the medulla of the adrenal glands that increases heart activity, improves the power and prolongs the action of muscles, and increases the rate and depth of breathing. It is synthesized by the methylation of norepinephrine.
51380	norepinephrine binding	F	Interacting selectively and non-covalently with norepinephrine, (3,4-dihydroxyphenyl-2-aminoethanol), a hormone secreted by the adrenal medulla and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts of the CNS. It is also the biosynthetic precursor of epinephrine.
51381	histamine binding	F	Interacting selectively and non-covalently with histamine, a physiologically active amine, found in plant and animal tissue and released from mast cells as part of an allergic reaction in humans.
51382	kinetochore assembly	P	The aggregation, arrangement and bonding together of a set of components to form the kinetochore, a multisubunit complex that is located at the centromeric region of DNA and provides an attachment point for the spindle microtubules.
51383	kinetochore organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the kinetochore, a multisubunit complex that is located at the centromeric region of DNA and provides an attachment point for the spindle microtubules.
51384	response to glucocorticoid	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucocorticoid stimulus. Glucocorticoids are hormonal C21 corticosteroids synthesized from cholesterol with the ability to bind with the cortisol receptor and trigger similar effects. Glucocorticoids act primarily on carbohydrate and protein metabolism, and have anti-inflammatory effects.
51385	response to mineralocorticoid	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mineralocorticoid stimulus. Mineralocorticoids are hormonal C21 corticosteroids synthesized from cholesterol and characterized by their similarity to aldosterone. Mineralocorticoids act primarily on water and electrolyte balance.
51386	regulation of neurotrophin TRK receptor signaling pathway	P	Any process that modulates the frequency, rate or extent of the neurotrophin TRK receptor signaling pathway.
51387	negative regulation of neurotrophin TRK receptor signaling pathway	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the neurotrophin TRK receptor signaling pathway.
51388	positive regulation of neurotrophin TRK receptor signaling pathway	P	Any process that activates or increases the frequency, rate or extent of the neurotrophin TRK receptor signaling pathway.
51389	inactivation of MAPKK activity	P	Any process that terminates the activity of the active enzyme MAP kinase kinase (MAPKK).
51390	inactivation of MAPKKK activity	P	Any process that terminates the activity of the active enzyme MAP kinase kinase kinase (MAPKKK).
51391	tRNA acetylation	P	The modification of tRNA structure by addition of an acetyl group to tRNA. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid.
51392	tRNA N-acetyltransferase activity	F	Catalysis of the reaction: acetyl-CoA + cytidine = CoA + N4-acetylcytidine. The cytidine is within the polynucleotide chain of a tRNA.
51393	alpha-actinin binding	F	Interacting selectively and non-covalently with alpha-actinin, one of a family of proteins that cross-link F-actin as antiparallel homodimers. Alpha-actinin has a molecular mass of 93-103 KDa; at the N-terminus there are two calponin homology domains, at the C-terminus there are two EF-hands. These two domains are connected by the rod domain. This domain is formed by triple-helical spectrin repeats.
51394	regulation of nerve growth factor receptor activity	P	Any process that modulates the frequency, rate or extent of the activity of the nerve growth factor (NGF) receptor.
51395	negative regulation of nerve growth factor receptor activity	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of the nerve growth factor (NGF) receptor.
51396	positive regulation of nerve growth factor receptor activity	P	Any process that activates or increases the frequency, rate or extent of the activity of the nerve growth factor (NGF) receptor.
51400	BH domain binding	F	Interacting selectively and non-covalently with the Bcl-2 homology (BH) domain of a protein. Bcl-2-related proteins share homology in one to four conserved regions designated the Bcl-2 homology (BH) domains BH1, BH2, BH3 and BH4. These domains contribute at multiple levels to the function of these proteins in cell death and survival. Anti-apoptotic members of the Bcl-2 family have four BH domains (BH1-BH4). Pro-apoptotic members have fewer BH domains.
51401	CH domain binding	F	Interacting selectively and non-covalently with the calponin homology domain of a protein, a domain of 100 residues that occurs in signaling and cytoskeletal proteins.
51402	neuron apoptotic process	P	Any apoptotic process in a neuron, the basic cellular unit of nervous tissue. Each neuron consists of a body, an axon, and dendrites. Their purpose is to receive, conduct, and transmit impulses in the nervous system.
51403	stress-activated MAPK cascade	P	A series of molecular signals in which a stress-activated MAP kinase cascade relays one or more of the signals; MAP kinase cascades involve at least three protein kinase activities and culminate in the phosphorylation and activation of a MAP kinase.
51407	glycerone phosphate:inorganic phosphate antiporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glycerone phosphate(out) + phosphate(in) = glycerone phosphate(in) + phosphate(out).
51408	glyceraldehyde 3-phosphate:inorganic phosphate antiporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glyceraldehyde 3-phosphate(out) + phosphate(in) = glyceraldehyde 3-phosphate(in) + phosphate(out).
51409	response to nitrosative stress	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrosative stress stimulus. Nitrosative stress is a state often resulting from exposure to high levels of nitric oxide (NO) or the highly reactive oxidant peroxynitrite, which is produced following interaction of NO with superoxide anions.
51410	detoxification of nitrogen compound	P	Any process that reduces or removes the toxicity of nitrogenous compounds which are dangerous or toxic. This includes the aerobic conversion of toxic compounds to harmless substances.
51412	response to corticosterone	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a corticosterone stimulus. Corticosterone is a 21 carbon steroid hormone of the corticosteroid type, produced in the cortex of the adrenal glands. In many species, corticosterone is the principal glucocorticoid, involved in regulation of fuel metabolism, immune reactions, and stress responses.
51413	response to cortisone	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cortisone stimulus. Cortisone is a natural glucocorticoid steroid hormone that is metabolically convertible to cortisol. Cortisone is synthesized from cholesterol in the cortex of the adrenal gland under the stimulation of adrenocorticotropin hormone (ACTH). The main physiological effect of cortisone is on carbohydrate metabolism; it can stimulate increased glucose release from the liver, increased liver glycogen synthesis, and decreased utilization of glucose by the tissues.
51414	response to cortisol	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cortisol stimulus. Cortisol is the major natural glucocorticoid synthesized in the zona fasciculata of the adrenal cortex; it affects the metabolism of glucose, protein, and fats and has appreciable mineralocorticoid activity. It also regulates the immune system and affects many other functions.
51415	interphase microtubule nucleation by interphase microtubule organizing center	P	The 'de novo' formation of a microtubule by the interphase microtubule organizing center during interphase, the stage of cell cycle between successive rounds of chromosome segregation.
51417	microtubule nucleation by spindle pole body	P	The 'de novo' formation of a microtubule, mediated by the spindle pole body.
51418	microtubule nucleation by microtubule organizing center	P	The 'de novo' formation of a microtubule, mediated by the microtubule organizing center.
51421	regulation of endo-1,4-beta-xylanase activity	P	Any process that modulates the frequency, rate or extent of endo-(1->4)-beta-xylanase activity, the catalysis of the endohydrolysis of (1->4)-beta-D-xylosidic linkages in xylans.
51422	negative regulation of endo-1,4-beta-xylanase activity	P	Any process that stops or reduces the rate of endo-(1->4)-beta-xylanase activity, the catalysis of the endohydrolysis of (1->4)-beta-D-xylosidic linkages in xylans.
51423	positive regulation of endo-1,4-beta-xylanase activity	P	Any process that activates or increases the frequency, rate or extent of endo-(1->4)-beta-xylanase activity, the catalysis of the endohydrolysis of (1->4)-beta-D-xylosidic linkages in xylans.
51424	corticotropin-releasing hormone binding	F	Interacting selectively and non-covalently with corticotropin-releasing hormone, a polypeptide hormone involved in the stress response. It is released by the hypothalamus and stimulates the release of corticotropin by the anterior pituitary gland.
51425	PTB domain binding	F	Interacting selectively and non-covalently with a phosphotyrosine-binding (PTB) domain of a protein.
51427	hormone receptor binding	F	Interacting selectively and non-covalently with a receptor for hormones.
51428	peptide hormone receptor binding	F	Interacting selectively and non-covalently with a receptor for peptide hormones.
51429	corticotropin-releasing hormone receptor binding	F	Interacting selectively and non-covalently with a receptor for corticotropin-releasing hormone (CRH), a polypeptide hormone involved in the stress response. It is released by the hypothalamus and stimulates the release of corticotropin by the anterior pituitary gland.
51430	corticotropin-releasing hormone receptor 1 binding	F	Interacting selectively and non-covalently with the corticotropin-releasing hormone receptor 1 (CRHR1). CRHR1 is the major subtype in the pituitary corticotroph, and mediates the stimulatory actions of corticotropin-releasing hormone on corticotropin hormone secretion. CRHR1 are also located in cortical areas of the brain, cerebellum and limbic system.
51431	corticotropin-releasing hormone receptor 2 binding	F	Interacting selectively and non-covalently with the corticotropin-releasing hormone receptor type 2 (CRHR2). The CRHR2 has several splice variants that are located in sub-cortical areas of the brain and in the periphery.
51432	BH1 domain binding	F	Interacting selectively and non-covalently with the BH1 domain of a protein of the Bcl-2 family. Proteins that act as inhibitors of apoptosis harbour at least three BH domains: BH1, BH2 and BH3; the BH1 and BH2 domains are found in all death antagonists of the Bcl-2 family but only in one class of death agonists.
51433	BH2 domain binding	F	Interacting selectively and non-covalently with the BH2 domain of a protein of the Bcl-2 family. Proteins that act as inhibitors of apoptosis harbour at least three BH domains: BH1, BH2 and BH3; the BH1 and BH2 domains are found in all death antagonists of the Bcl-2 family but only in one class of death agonists.
51434	BH3 domain binding	F	Interacting selectively and non-covalently with the BH3 domain of a protein of the Bcl-2 family. The BH3 domain is a potent death domain and has an important role in protein-protein interactions and in cell death.
51435	BH4 domain binding	F	Interacting selectively and non-covalently with the BH4 domain of a protein of the Bcl-2 family. All anti-apoptotic proteins contain BH1 and BH2 domains; some also contain an additional N-terminal BH4 domain, which is almost never seen in pro-apoptotic proteins. Loss of the BH4 domain can diminish or abrogate anti-apoptotic function or even impart outright death-promoting properties to the protein.
51436	negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	P	Any process that stops, prevents, or reduces the frequency, rate or extent of ubiquitin ligase activity that contributes to the mitotic cell cycle.
51437	positive regulation of ubiquitin-protein ligase activity involved in regulation of mitotic cell cycle transition	P	Any process that activates, maintains or increases the rate of ubiquitin ligase activity that contributes to the regulation of the mitotic cell cycle phase transition.
51438	regulation of ubiquitin-protein transferase activity	P	Any process that modulates the frequency, rate or extent of ubiquitin transferase activity.
51439	regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle	P	A cell cycle process that modulates the frequency, rate or extent of ubiquitin ligase activity that contributes to the mitotic cell cycle.
51440	regulation of ubiquitin-protein ligase activity involved in meiotic cell cycle	P	A cell cycle process that modulates the frequency, rate or extent of ubiquitin ligase activity during the meiotic cell cycle.
51441	positive regulation of ubiquitin-protein ligase activity involved in meiotic cell cycle	P	Any process that activates, maintains or increases the rate of ubiquitin ligase activity during the meiotic cell cycle.
51442	negative regulation of ubiquitin-protein ligase activity involved in meiotic cell cycle	P	Any process that stops, prevents, or reduces the frequency, rate or extent of ubiquitin ligase activity during the meiotic cell cycle.
51443	positive regulation of ubiquitin-protein transferase activity	P	Any process that activates, maintains or increases the rate of ubiquitin transferase activity.
51444	negative regulation of ubiquitin-protein transferase activity	P	Any process that stops, prevents, or reduces the frequency, rate or extent of ubiquitin transferase activity.
51445	regulation of meiotic cell cycle	P	Any process that modulates the rate or extent of progression through the meiotic cell cycle.
51446	positive regulation of meiotic cell cycle	P	Any process that activates or increases the frequency, rate or extent of progression through the meiotic cell cycle.
51447	negative regulation of meiotic cell cycle	P	Any process that stops, prevents or reduces the rate or extent of progression through the meiotic cell cycle.
51448	gonadotropin-releasing hormone binding	F	Interacting selectively and non-covalently with gonadotropin-releasing hormone (GnRH), a peptide hormone responsible for the release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) from the anterior pituitary. GnRH is synthesized and released by the hypothalamus.
51449	thyrotropin-releasing hormone binding	F	Interacting selectively and non-covalently with thyrotropin-releasing hormone, a tripeptide hormone that stimulates the release of thyroid-stimulating hormone (TSH) and prolactin by the anterior pituitary and it is produced by the hypothalamus and travels across the median eminence to the pituitary via the pituitary portal system.
51450	myoblast proliferation	P	The multiplication or reproduction of myoblasts, resulting in the expansion of a myoblast cell population. A myoblast is a mononucleate cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.
51451	myoblast migration	P	The orderly movement of a myoblast from one site to another, often during the development of a multicellular organism. A myoblast is a cell type that, by fusion with other myoblasts, gives rise to the myotubes that eventually develop into skeletal muscle fibers.
51452	intracellular pH reduction	P	Any process that reduces the internal pH of a cell, measured by the concentration of the hydrogen ion.
51453	regulation of intracellular pH	P	Any process that modulates the internal pH of a cell, measured by the concentration of the hydrogen ion.
51454	intracellular pH elevation	P	Any process that increases the internal pH of a cell, measured by the concentration of the hydrogen ion.
51455	attachment of spindle microtubules to kinetochore involved in homologous chromosome segregation	P	The process in which spindle microtubules become physically associated with the proteins making up the kinetochore complex during meiosis I. During meiosis I sister kinetochores are lying next to each other facing the same spindle pole and monopolar attachment of the chromatid to the spindle occurs.
51456	attachment of spindle microtubules to kinetochore involved in meiotic sister chromatid segregation	P	The process in which spindle microtubules become physically associated with the proteins making up the kinetochore complex during meiosis II. During meiosis II sister kinetochores are situated facing opposite spindle poles and bipolar attachment of the sister chromosomes to the spindle occurs.
51457	maintenance of protein location in nucleus	P	Any process in which a protein is maintained in the nucleus and prevented from moving elsewhere. These include sequestration within the nucleus, protein stabilization to prevent transport elsewhere and the active retrieval of proteins that escape the nucleus.
51458	corticotropin secretion	P	The regulated release of corticotropin by a cell. Corticotropin hormone is a polypeptide hormone synthesized and secreted from corticotropes in the anterior lobe of the pituitary gland in response to corticotropin-releasing hormone (CRH) released by the hypothalamus.
51459	regulation of corticotropin secretion	P	Any process that modulates the frequency, rate or extent of the regulated release of corticotropic hormone from a cell.
51460	negative regulation of corticotropin secretion	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of corticotropic hormone from a cell.
51461	positive regulation of corticotropin secretion	P	Any process that activates or increases the frequency, rate or extent of the regulated release of corticotropin hormone from a cell.
51462	regulation of cortisol secretion	P	Any process that modulates the frequency, rate or extent of the regulated release of cortisol from a cell.
51463	negative regulation of cortisol secretion	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of cortisol from a cell.
51464	positive regulation of cortisol secretion	P	Any process that activates or increases the frequency, rate or extent of the regulated release of cortisol from a cell.
51465	negative regulation of corticotropin-releasing hormone secretion	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of corticotropin-releasing hormone from a cell.
51466	positive regulation of corticotropin-releasing hormone secretion	P	Any process that activates or increases the frequency, rate or extent of the regulated release of corticotropin-releasing hormone from a cell.
51467	detection of steroid hormone stimulus	P	The series of events by which a steroid hormone stimulus is received by a cell and converted into a molecular signal.
51468	detection of glucocorticoid hormone stimulus	P	The series of events by which a glucocorticoid hormone stimulus is received by a cell and converted into a molecular signal. Glucocorticoids are hormonal C21 corticosteroids synthesized from cholesterol with the ability to bind with the cortisol receptor and trigger similar effects. Glucocorticoids act primarily on carbohydrate and protein metabolism, and have anti-inflammatory effects.
51469	vesicle fusion with vacuole	P	The joining of the lipid bilayer membrane around a vesicle with the lipid bilayer membrane around the vacuole.
51470	ectoine transport	P	The directed movement of ectoine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidinecarboxylic acid) is a tetrahydropyrimidine commonly synthesized by halophilic bacteria.
51471	ectoine transmembrane transporter activity	F	Enables the transfer of ectoine from one side of the membrane to the other. Ectoine (1,4,5,6-tetrahydro-2-methyl-4-pyrimidinecarboxylic acid) is a tetrahydropyrimidine commonly synthesized by halophilic bacteria.
51472	glucosylglycerol metabolic process	P	The chemical reactions and pathways involving glucosylglycerol, alpha-D-glucopyranosyl-alpha-(1,2)-glycerol.
51473	glucosylglycerol biosynthetic process	P	The chemical reactions and pathways resulting in the formation of glucosylglycerol, alpha-D-glucopyranosyl-alpha-(1,2)-glycerol.
51474	glucosylglycerol transmembrane transporter activity	F	Enables the transfer of a glucosylglycerol from one side of the membrane to the other. A glucosylglycerol is an alpha-D-glucopyranosyl-alpha-(1,2)-glycerol.
51475	glucosylglycerol transport	P	The directed movement of glucosylglycerol, alpha-D-glucopyranosyl-alpha-(1,2)-glycerol, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
51476	mannosylglycerate transport	P	The directed movement of mannosylglycerate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
51477	mannosylglycerate transmembrane transporter activity	F	Enables the transfer of a mannosylglycerate from one side of the membrane to the other.
51478	mannosylglycerate metabolic process	P	The chemical reactions and pathways involving mannosylglycerate, a very common compatible solute in thermophilic and hyperthermophilic organisms.
51479	mannosylglycerate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of mannosylglycerate, a very common compatible solute in thermophilic and hyperthermophilic organisms.
51480	regulation of cytosolic calcium ion concentration	P	Any process involved in the maintenance of an internal steady state of calcium ions within the cytosol of a cell or between the cytosol and its surroundings.
51481	negative regulation of cytosolic calcium ion concentration	P	Any process that decreases the concentration of calcium ions in the cytosol.
51482	positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway	P	Any process that increases the concentration of calcium ions in the cytosol that occurs as part of a PLC-activating G-protein coupled receptor signaling pathway. G-protein-activated PLC hydrolyses phosphatidylinositol-bisphosphate (PIP2) to release diacylglycerol (DAG) and inositol trisphosphate (IP3). IP3 then binds to calcium release channels in the endoplasmic reticulum (ER) to trigger calcium ion release into the cytosol.
51483	terpenoid biosynthetic process, mevalonate-independent	P	The chemical reactions and pathways resulting in the formation of terpenoids, independent of mevalonate. Isopentenyl diphosphate (IPP) is the fundamental unit in terpenoid biosynthesis, and in mevalonate-independent biosynthesis, it is produced from pyruvate and glyceraldehyde 3-phosphate via intermediates including 1-deoxy-D-xylulose 5-phosphate.
51484	isopentenyl diphosphate biosynthetic process, methylerythritol 4-phosphate pathway involved in terpenoid biosynthetic process	P	The chemical reactions and pathways resulting in the formation of isopentenyl diphosphate by the mevalonate-independent pathway that contributes to terpenoid biosynthesis. Isopentenyl diphosphate (IPP) is the fundamental unit in isoprenoid biosynthesis and is biosynthesized from pyruvate and glyceraldehyde 3-phosphate via intermediates, including 1-deoxy-D-xylulose 5-phosphate.
51485	terpenoid biosynthetic process, mevalonate-dependent	P	The chemical reactions and pathways resulting in the formation of terpenoids via isopentenyl diphosphate, synthesized by the mevalonate pathway. Isopentenyl diphosphate (IPP) is the fundamental unit in terpenoid biosynthesis, and in mevalonate-dependent terpenoid biosynthesis, acetate, in the form of acetyl-CoA, is converted to isopentenyl diphosphate (IPP) through a series of mevalonate intermediates.
51486	isopentenyl diphosphate biosynthetic process, mevalonate pathway involved in terpenoid biosynthetic process	P	The chemical reactions and pathways resulting in the formation of isopentenyl diphosphate by the mevalonate pathway that contributes to terpenoid biosynthesis. This pathway converts acetate, in the form of acetyl-CoA, to isopentenyl diphosphate (IPP) through a series of mevalonate intermediates.
51489	regulation of filopodium assembly	P	Any process that modulates the frequency, rate or extent of the assembly of a filopodium, a thin, stiff protrusion extended by the leading edge of a motile cell such as a crawling fibroblast or amoeba, or an axonal growth cone.
51490	negative regulation of filopodium assembly	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the assembly of a filopodium, a thin, stiff protrusion extended by the leading edge of a motile cell such as a crawling fibroblast or amoeba, or an axonal growth cone.
51491	positive regulation of filopodium assembly	P	Any process that activates or increases the frequency, rate or extent of the assembly of a filopodium, a thin, stiff protrusion extended by the leading edge of a motile cell such as a crawling fibroblast or amoeba, or an axonal growth cone.
51492	regulation of stress fiber assembly	P	Any process that modulates the frequency, rate or extent of the assembly of a stress fiber, a bundle of microfilaments and other proteins found in fibroblasts.
51493	regulation of cytoskeleton organization	P	Any process that modulates the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures.
51494	negative regulation of cytoskeleton organization	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures.
51495	positive regulation of cytoskeleton organization	P	Any process that activates or increases the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures.
51496	positive regulation of stress fiber assembly	P	Any process that activates or increases the frequency, rate or extent of the assembly of a stress fiber, a bundle of microfilaments and other proteins found in fibroblasts.
51497	negative regulation of stress fiber assembly	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the assembly a stress fiber, a bundle of microfilaments and other proteins found in fibroblasts.
51498	syn-copalyl diphosphate synthase activity	F	Catalysis of the reaction: geranylgeranyl diphosphate = 9alpha-copalyl diphosphate.
51499	D-aminoacyl-tRNA deacylase activity	F	Catalysis of the reaction: D-aminoacyl-tRNA = D-amino acid + tRNA. Hydrolysis of the removal of D-amino acids from residues in charged tRNA.
51500	D-tyrosyl-tRNA(Tyr) deacylase activity	F	Catalysis of the reaction: D-tyrosyl-tRNA(Tyr) = D-tyrosine + tRNA(Tyr). Hydrolysis of the removal of D-tyrosine from tyrosine residues in charged tRNA.
51501	diterpene phytoalexin metabolic process	P	The chemical reactions and pathways involving diterpene phytoalexins, a class of diterpene formed in plants in response to fungal infection, physical damage, chemical injury, or a pathogenic process; they are sometimes referred to as plant antibiotics. Diterpenes are unsaturated hydrocarbons containing 20 carbon atoms and 4 branched methyl groups and are made up of isoprenoid units.
51502	diterpene phytoalexin biosynthetic process	P	The chemical reactions and pathways resulting in the formation of diterpene phytoalexins, terpenoids with 20 carbons produced by plants in response to environmental stresses.
51503	adenine nucleotide transport	P	The directed movement of adenine nucleotides, ATP, ADP, and/or AMP, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
51504	diterpene phytoalexin precursor biosynthetic process pathway	P	A branched pathway that produces the precursors to four structurally distinct types of polycyclic diterpenes. The pathway starts with the cyclization of geranylgeranyl diphosphate into ent-copalyl diphosphate and syn-copalyl diphosphate. The catalytic conversion by diterpene cyclases of these two compounds produces the four diterpene hydrocarbons which are precursors to the four structurally distinct classes of diterpene phytoalexins.
51505	cholesterol UDP-glucosyltransferase activity	F	Catalysis of the reaction: UDP-glucose + a sterol = UDP + O-glucosyl-cholesterol.
51506	ergosterol UDP-glucosyltransferase activity	F	Catalysis of the reaction: UDP-glucose + a sterol = UDP + O-glucosyl-ergosterol.
51507	beta-sitosterol UDP-glucosyltransferase activity	F	Catalysis of the reaction: UDP-glucose + a sterol = UDP + O-glucosyl-beta-sitosterol.
51508	stigmasterol UDP-glucosyltransferase activity	F	Catalysis of the reaction: UDP-glucose + a sterol = UDP + O-glucosyl-stigmasterol.
51509	tomatidine UDP-glucosyltransferase activity	F	Catalysis of the reaction: UDP-glucose + a sterol = UDP + O-glucosyl-tomatidine.
51510	regulation of unidimensional cell growth	P	Any process that modulates the frequency, rate or extent of unidimensional cell growth, the process in which a cell irreversibly increases in size in one [spatial] dimension or along one axis.
51511	negative regulation of unidimensional cell growth	P	Any process that stops, prevents, or reduces the frequency, rate or extent of unidimensional cell growth, the process in which a cell irreversibly increases in size in one [spatial] dimension or along one axis.
51512	positive regulation of unidimensional cell growth	P	Any process that activates or increases the frequency, rate or extent of unidimensional cell growth, the process in which a cell irreversibly increases in size in one [spatial] dimension or along one axis.
51513	regulation of monopolar cell growth	P	Any process that modulates the frequency, rate or extent of monopolar cell growth, polarized growth from one end of a cell.
51514	negative regulation of monopolar cell growth	P	Any process that stops, prevents, or reduces the frequency, rate or extent of monopolar cell growth, polarized growth from one end of a cell.
51515	positive regulation of monopolar cell growth	P	Any process that activates or increases the frequency, rate or extent of monopolar cell growth, polarized growth from one end of a cell.
51516	regulation of bipolar cell growth	P	Any process that modulates the frequency, rate or extent of bipolar cell growth, polarized growth from both ends of a cell.
51517	negative regulation of bipolar cell growth	P	Any process that stops, prevents, or reduces the frequency, rate or extent of bipolar cell growth, polarized growth from both ends of a cell.
51518	positive regulation of bipolar cell growth	P	Any process that activates or increases the frequency, rate or extent of bipolar cell growth, polarized growth from both ends of a cell.
51519	activation of bipolar cell growth	P	Any process that initiates the inactive process of bipolar cell growth, polarized growth from both ends of a cell.
51520	termination of bipolar cell growth	P	Any process that stops the active process of bipolar cell growth, polarized growth from both ends of a cell.
51521	termination of monopolar cell growth	P	Any process that stops the active process of bipolar cell growth, polarized growth from one end of a cell.
51522	activation of monopolar cell growth	P	Any process that initiates the inactive process of monopolar cell growth, polarized growth from one end of a cell.
51523	cell growth mode switching, monopolar to bipolar	P	The process in which a cell switches from monopolar cell growth to bipolar cell growth.
51524	cell growth mode switching, bipolar to monopolar	P	The process in which a cell switches from bipolar cell growth to monopolar cell growth.
51525	NFAT protein binding	F	Interacting selectively and non-covalently with NFAT (nuclear factor of activated T cells) proteins, a family of transcription factors. NFAT proteins have crucial roles in the development and function of the immune system.
51531	NFAT protein import into nucleus	P	The directed movement of NFAT (nuclear factor of activated T cells) proteins, a family of transcription factors, from the cytoplasm into the nucleus. NFAT proteins are dephosphorylated in the cytoplasm by activated calcineurin, which leads to their translocation across the nuclear membrane.
51532	regulation of NFAT protein import into nucleus	P	Any process that modulates the frequency, rate or extent of the movement of an NFAT protein from the cytoplasm to the nucleus.
51533	positive regulation of NFAT protein import into nucleus	P	Any process that activates or increases the frequency, rate or extent of the movement of an NFAT protein from the cytoplasm to the nucleus.
51534	negative regulation of NFAT protein import into nucleus	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the movement of an NFAT protein from the cytoplasm to the nucleus.
51536	iron-sulfur cluster binding	F	Interacting selectively and non-covalently with an iron-sulfur cluster, a combination of iron and sulfur atoms.
51537	2 iron, 2 sulfur cluster binding	F	Interacting selectively and non-covalently with a 2 iron, 2 sulfur (2Fe-2S) cluster; this cluster consists of two iron atoms, with two inorganic sulfur atoms found between the irons and acting as bridging ligands.
51538	3 iron, 4 sulfur cluster binding	F	Interacting selectively and non-covalently with a 3 iron, 4 sulfur (3Fe-4S) cluster; this cluster consists of three iron atoms, with the inorganic sulfur atoms found between the irons and acting as bridging ligands. It is essentially a 4Fe-4S cluster with one iron missing.
51539	4 iron, 4 sulfur cluster binding	F	Interacting selectively and non-covalently with a 4 iron, 4 sulfur (4Fe-4S) cluster; this cluster consists of four iron atoms, with the inorganic sulfur atoms found between the irons and acting as bridging ligands.
51540	metal cluster binding	F	Interacting selectively and non-covalently with a cluster of atoms including both metal ions and nonmetal atoms, usually sulfur and oxygen. Examples include iron-sulfur clusters and nickel-iron-sulfur clusters.
51541	elastin metabolic process	P	The chemical reactions and pathways involving elastin, a glycoprotein which is randomly coiled and crosslinked to form elastic fibers that are found in connective tissue.
51542	elastin biosynthetic process	P	The chemical reactions and pathways resulting in the formation of elastin, a fibrous glycoprotein found in elastic tissues such as the walls of arteries.
51543	regulation of elastin biosynthetic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of elastin.
51544	positive regulation of elastin biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of elastin.
51545	negative regulation of elastin biosynthetic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of elastin.
51546	keratinocyte migration	P	The directed movement of a keratinocyte, epidermal cells which synthesize keratin, from one site to another.
51547	regulation of keratinocyte migration	P	Any process that modulates the frequency, rate or extent of keratinocyte migration.
51548	negative regulation of keratinocyte migration	P	Any process that stops, prevents, or reduces the frequency, rate or extent of keratinocyte migration.
51549	positive regulation of keratinocyte migration	P	Any process that activates or increases the frequency, rate or extent of keratinocyte migration.
51550	aurone metabolic process	P	The chemical reactions and pathways involving aurones, a series of plant flavonoids that provide a yellow colour to flowers. They have the basic skeletal structure of two benzene rings joined by a linear C3 chain (C6-C3-C6). Aurones exist mostly as 6-O-glucosides.
51551	aurone biosynthetic process	P	The chemical reactions and pathways resulting in the formation of aurones, a series of yellow plant pigments.
51552	flavone metabolic process	P	The chemical reactions and pathways involving flavones, a class of pigmented plant compounds based on 2-phenyl-4H-1-benzopyran-4-one (2-phenylchromone).
51553	flavone biosynthetic process	P	The chemical reactions and pathways resulting in the formation of flavones, a class of pigmented plant compounds based on 2-phenyl-4H-1-benzopyran-4-one (2-phenylchromone).
51554	flavonol metabolic process	P	The chemical reactions and pathways involving flavonols, a member of a class of vascular pigments formed by consecutive oxidative processes from the flavonoid intermediates flavanones and dihydroflavonols. Flavonols are the most widespread of the flavonoids and have a wide array of physiological activities.
51555	flavonol biosynthetic process	P	The chemical reactions and pathways resulting in the formation of flavonols, a member of a class of vascular pigments formed by consecutive oxidative processes from the flavonoid intermediates flavanones and dihydroflavonols. Flavonols are the most widespread of the flavonoids and have a wide array of physiological activities.
51556	leucoanthocyanidin metabolic process	P	The chemical reactions and pathways involving leucoanthocyanidins, a class of colorless intermediates in the biosynthetic pathway of the pigmented flavonoids.
51557	leucoanthocyanidin biosynthetic process	P	The chemical reactions and pathways resulting in the formation of leucoanthocyanidins, a class of colorless intermediates in the biosynthetic pathway of the pigmented flavonoids.
51558	phlobaphene metabolic process	P	The chemical reactions and pathways involving phlobaphenes, red pigments with oligomeric or polymeric structure derived from the flavonoid intermediate flavan-4-ols.
51559	phlobaphene biosynthetic process	P	The chemical reactions and pathways resulting in the formation of phlobaphenes, red pigments with oligomeric or polymeric structure derived from the flavonoid intermediate flavan-4-ols.
51560	mitochondrial calcium ion homeostasis	P	Any process involved in the maintenance of an internal steady state of calcium ions within the cytoplasm of a cell or between mitochondria and their surroundings.
51561	positive regulation of mitochondrial calcium ion concentration	P	Any process that increases the concentration of calcium ions in mitochondria.
51562	negative regulation of mitochondrial calcium ion concentration	P	Any process that decreases the concentration of calcium ions in mitochondria.
51563	smooth endoplasmic reticulum calcium ion homeostasis	P	Any process involved in the maintenance of an internal steady state of calcium ions within the smooth endoplasmic reticulum of a cell or between the smooth endoplasmic reticulum and its surroundings.
51564	positive regulation of smooth endoplasmic reticulum calcium ion concentration	P	Any process that increases the concentration of calcium ions in the smooth endoplasmic reticulum.
51565	negative regulation of smooth endoplasmic reticulum calcium ion concentration	P	Any process that decreases the concentration of calcium ions in the smooth endoplasmic reticulum.
51566	anthocyanidin-3-glucoside rhamnosyltransferase activity	F	Catalysis of the reaction: anthocyanidin 3-glucoside + UDP-rhamnose = anthocyanidin 3-rutinoside + UDP.
51567	histone H3-K9 methylation	P	The modification of histone H3 by addition of one or more methyl groups to lysine at position 9 of the histone.
51568	histone H3-K4 methylation	P	The modification of histone H3 by addition of one or more methyl groups to lysine at position 4 of the histone.
51569	regulation of histone H3-K4 methylation	P	Any process that modulates the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 4 of histone H3.
51570	regulation of histone H3-K9 methylation	P	Any process that modulates the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 9 of histone H3.
51571	positive regulation of histone H3-K4 methylation	P	Any process that activates or increases the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 4 of histone H3.
51572	negative regulation of histone H3-K4 methylation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 4 of histone H3.
51573	negative regulation of histone H3-K9 methylation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 9 of histone H3.
51574	positive regulation of histone H3-K9 methylation	P	Any process that activates or increases the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 9 of histone H3.
51575	5'-deoxyribose-5-phosphate lyase activity	F	Catalysis of the beta-elimination of the 5' deoxyribose-5-phosphate at an abasic site in DNA where a DNA-(apurinic or apyrimidinic site) lyase has already cleaved the C-O-P bond 3' to the apurinic or apyrimidinic site.
51580	regulation of neurotransmitter uptake	P	Any process that modulates the frequency, rate or extent of the directed movement of a neurotransmitter into a neuron or glial cell.
51581	negative regulation of neurotransmitter uptake	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a neurotransmitter into a neuron or glial cell.
51582	positive regulation of neurotransmitter uptake	P	Any process that activates or increases the frequency, rate or extent of the directed movement of a neurotransmitter into a neuron or glial cell.
51583	dopamine uptake involved in synaptic transmission	P	The directed movement of dopamine into a presynaptic neuron or glial cell. In this context, dopamine is a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline.
51584	regulation of dopamine uptake involved in synaptic transmission	P	Any process that modulates the frequency, rate or extent of the directed movement of the catecholamine neurotransmitter dopamine into a cell.
51585	negative regulation of dopamine uptake involved in synaptic transmission	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of dopamine into a presynaptic neuron or glial cell.
51586	positive regulation of dopamine uptake involved in synaptic transmission	P	Any process that activates or increases the frequency, rate or extent of the directed movement of dopamine into a cell.
51587	inhibition of dopamine uptake involved in synaptic transmission	P	Any process that prevents the activation of the directed movement of dopamine into a cell.
51588	regulation of neurotransmitter transport	P	Any process that modulates the frequency, rate or extent of the directed movement of a neurotransmitter into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
51589	negative regulation of neurotransmitter transport	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of a neurotransmitter into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
51590	positive regulation of neurotransmitter transport	P	Any process that activates or increases the frequency, rate or extent of the directed movement of a neurotransmitter into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
51591	response to cAMP	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate) stimulus.
51592	response to calcium ion	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a calcium ion stimulus.
51593	response to folic acid	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a folic acid stimulus.
51594	detection of glucose	P	The series of events in which a glucose stimulus is received by a cell and converted into a molecular signal.
51595	response to methylglyoxal	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methylglyoxal stimulus. Methylglyoxal is a 2-oxoaldehyde derived from propanal.
51596	methylglyoxal catabolic process	P	The chemical reactions and pathways resulting in the breakdown of methylglyoxal, CH3-CO-CHO, the aldehyde of pyruvic acid.
51597	response to methylmercury	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methylmercury stimulus.
51598	meiotic recombination checkpoint	P	A checkpoint that acts during late prophase I (pachytene) and prevents segregation of homologous chromosomes until recombination is completed, ensuring proper distribution of the genetic material to the gametes.
51599	response to hydrostatic pressure	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrostatic pressure stimulus. Hydrostatic pressure is the force acting on an object in a system where the fluid is at rest (as opposed to moving). The weight of the fluid above the object creates pressure on it.
51600	regulation of endocytosis by exocyst localization	P	Any process in which an exocyst is transported to, or maintained in, a specific location that results in the modulation of endocytosis. An exocyst is a protein complex peripherally associated with the plasma membrane that determines where vesicles dock and fuse.
51601	exocyst localization	P	Any process in which an exocyst is transported to, or maintained in, a specific location. An exocyst is a protein complex peripherally associated with the plasma membrane that determines where vesicles dock and fuse.
51602	response to electrical stimulus	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electrical stimulus.
51603	proteolysis involved in cellular protein catabolic process	P	The hydrolysis of a peptide bond or bonds within a protein as part of the chemical reactions and pathways resulting in the breakdown of a protein by individual cells.
51604	protein maturation	P	Any process leading to the attainment of the full functional capacity of a protein.
51606	detection of stimulus	P	The series of events in which a stimulus is received by a cell or organism and converted into a molecular signal.
51607	defense response to virus	P	Reactions triggered in response to the presence of a virus that act to protect the cell or organism.
51608	histamine transport	P	The directed movement of histamine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Histamine is a physiologically active amine, found in plant and animal tissue and released from mast cells as part of an allergic reaction in humans.
51609	inhibition of neurotransmitter uptake	P	Any process that prevents the activation of the directed movement of a neurotransmitter into a cell.
51610	serotonin uptake	P	The directed movement of serotonin into a cell, typically presynaptic neurons or glial cells. Serotonin (5-hydroxytryptamine) is a monoamine neurotransmitter occurring in the peripheral and central nervous systems.
51611	regulation of serotonin uptake	P	Any process that modulates the frequency, rate or extent of the directed movement of the monoamine neurotransmitter serotonin into a cell.
51612	negative regulation of serotonin uptake	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of serotonin into a cell.
51613	positive regulation of serotonin uptake	P	Any process that activates or increases the frequency, rate or extent of the directed movement of serotonin into a cell.
51614	inhibition of serotonin uptake	P	Any process that prevents the activation of the directed movement of serotonin into a cell.
51615	histamine uptake	P	The directed movement of histamine into a cell, typically presynaptic neurons or glial cells. Histamine is a physiologically active amine, found in plant and animal tissue and released from mast cells as part of an allergic reaction in humans.
51616	regulation of histamine uptake	P	Any process that modulates the frequency, rate or extent of the directed movement of the neurotransmitter histamine into a cell.
51617	negative regulation of histamine uptake	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of histamine into a cell.
51618	positive regulation of histamine uptake	P	Any process that activates or increases the frequency, rate or extent of the directed movement of histamine into a cell.
51619	inhibition of histamine uptake	P	Any process that prevents the activation of the directed movement of histamine into a cell.
51620	norepinephrine uptake	P	The directed movement of norepinephrine into a cell, typically presynaptic neurons or glial cells. Norepinephrine (3,4-dihydroxyphenyl-2-aminoethanol) is a hormone secreted by the adrenal medulla and a neurotransmitter in the sympathetic peripheral nervous system and in some tracts of the CNS. It is also the biosynthetic precursor of epinephrine.
51621	regulation of norepinephrine uptake	P	Any process that modulates the frequency, rate or extent of the directed movement of the neurotransmitter norepinephrine into a cell.
51622	negative regulation of norepinephrine uptake	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of norepinephrine into a cell.
51623	positive regulation of norepinephrine uptake	P	Any process that activates or increases the frequency, rate or extent of the directed movement of norepinephrine into a cell.
51624	inhibition of norepinephrine uptake	P	Any process that prevents the activation of the directed movement of norepinephrine into a cell.
51625	epinephrine uptake	P	The directed movement of epinephrine into a cell, typically presynaptic neurons or glial cells. Epinephrine is a hormone produced by the medulla of the adrenal glands that increases heart activity, improves the power and prolongs the action of muscles, and increases the rate and depth of breathing. It is synthesized by the methylation of norepinephrine.
51626	regulation of epinephrine uptake	P	Any process that modulates the frequency, rate or extent of the directed movement of the neurotransmitter epinephrine into a cell.
51627	negative regulation of epinephrine uptake	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of epinephrine into a cell.
51628	positive regulation of epinephrine uptake	P	Any process that activates or increases the frequency, rate or extent of the directed movement of epinephrine into a cell.
51629	inhibition of epinephrine uptake	P	Any process that prevents the activation of the directed movement of epinephrine into a cell.
51630	acetylcholine uptake	P	The directed movement of acetylcholine into a cell, typically presynaptic neurons or glial cells. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues.
51631	regulation of acetylcholine uptake	P	Any process that modulates the frequency, rate or extent of the directed movement of the neurotransmitter acetylcholine into a cell.
51632	negative regulation of acetylcholine uptake	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of acetylcholine into a cell.
51633	positive regulation of acetylcholine uptake	P	Any process that activates or increases the frequency, rate or extent of the directed movement of acetylcholine into a cell.
51634	inhibition of acetylcholine uptake	P	Any process that prevents the activation of the directed movement of acetylcholine into a cell.
51638	barbed-end actin filament uncapping	P	The removal of capping protein from the barbed (or plus) end of actin filaments to free the ends for addition, exchange or removal of further actin subunits.
51639	actin filament network formation	P	The assembly of a network of actin filaments; actin filaments on different axes and with differing orientations are crosslinked together to form a mesh of filaments.
51640	organelle localization	P	Any process in which an organelle is transported to, and/or maintained in, a specific location.
51641	cellular localization	P	A cellular localization process whereby a substance or cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in, a specific location within a cell including the localization of substances or cellular entities to the cell membrane.
51642	centrosome localization	P	Any process in which a centrosome is transported to, and/or maintained in, a specific location within the cell.
51643	endoplasmic reticulum localization	P	Any process in which endoplasmic reticulum is transported to, and/or maintained in, a specific location within the cell.
51644	plastid localization	P	Any process in which a plastid is transported to, and/or maintained in, a specific location within the cell.
51645	Golgi localization	P	Any process in which the Golgi is transported to, and/or maintained in, a specific location within the cell.
51646	mitochondrion localization	P	Any process in which a mitochondrion or mitochondria are transported to, and/or maintained in, a specific location within the cell.
51647	nucleus localization	P	Any process in which the nucleus is transported to, and/or maintained in, a specific location within the cell.
51648	vesicle localization	P	Any process in which a vesicle or vesicles are transported to, and/or maintained in, a specific location.
51649	establishment of localization in cell	P	Any process, occuring in a cell, that localizes a substance or cellular component. This may occur via movement, tethering or selective degradation.
51650	establishment of vesicle localization	P	The directed movement of a vesicle to a specific location.
51651	maintenance of location in cell	P	Any process in which a substance or cellular entity, such as a protein complex or organelle, is maintained in a specific location within, or in the membrane of, a cell, and is prevented from moving elsewhere.
51652	maintenance of chromosome location	P	Any process in which a chromosome is maintained in a specific location within a cell and prevented from moving elsewhere.
51653	spindle localization	P	Any process in which is the spindle is transported to, and/or maintained in, a specific location.
51654	establishment of mitochondrion localization	P	The directed movement of the mitochondrion to a specific location.
51655	maintenance of vesicle location	P	Any process in which a vesicle is maintained in a specific location within a cell and prevented from moving elsewhere.
51656	establishment of organelle localization	P	The directed movement of an organelle to a specific location.
51657	maintenance of organelle location	P	Any process in which an organelle is maintained in a specific location within a cell and prevented from moving elsewhere.
51658	maintenance of nucleus location	P	Any process in which the nucleus is maintained in a specific location within a cell and prevented from moving elsewhere.
51659	maintenance of mitochondrion location	P	Any process in which a mitochondrion is maintained in a specific location within a cell and prevented from moving elsewhere.
51660	establishment of centrosome localization	P	The directed movement of the centrosome to a specific location.
51661	maintenance of centrosome location	P	Any process in which a centrosome is maintained in a specific location within a cell and prevented from moving elsewhere.
51663	oocyte nucleus localization involved in oocyte dorsal/ventral axis specification	P	The directed movement of the nucleus to a specific location within a cell during the establishment and maintenance of the dorsal/ventral axis of the oocyte.
51664	nuclear pore localization	P	Any process in which nuclear pores are transported to, or maintained in, a specific location.
51665	membrane raft localization	P	Any process in which membrane rafts are transported to, or maintained in, a specific location. Membrane rafts are small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes.
51666	actin cortical patch localization	P	Any process in which actin cortical patches are transported to, or maintained in, a specific location. An actin cortical patch is a discrete actin-containing structure found just beneath the plasma membrane in fungal cells.
51667	establishment of plastid localization	P	The directed movement of a plastid to a specific location in the cell.
51668	localization within membrane	P	Any process in which a substance or cellular entity, such as a protein complex or organelle, is transported to, and/or maintained in, a specific location within a membrane.
51669	fructan beta-fructosidase activity	F	Catalysis of the hydrolysis of terminal, non-reducing 2,1- and 2,6-linked beta-D-fructofuranose residues in fructans.
51670	inulinase activity	F	Catalysis of the endohydrolysis of 2,1-beta-D-fructosidic linkages in inulin.
51671	induction of autolysin activity in other organism	P	Any process in which an organism initiates the activity of the inactive enzyme autolysin in another organism. The autolysin enzyme belongs to, and is active in, the other organism.
51672	catabolism by organism of cell wall peptidoglycan in other organism	P	The chemical reactions and pathways resulting in the breakdown of the cell wall peptidoglycans of another organism.
51673	membrane disruption in other organism	P	The disruption of the membranes of another organism, leading to damage to its cells and possibly death of that organism.
51674	localization of cell	P	Any process in which a cell is transported to, and/or maintained in, a specific location.
51675	isopullulanase activity	F	Catalysis of the hydrolysis of pullulan to isopanose (6-alpha-maltosylglucose).
51676	pullulan metabolic process	P	The chemical reactions and pathways involving pullulan, a neutral linear polysaccharide composed of repeating units of maltotriose joined by alpha-(1,6)-linkages.
51677	pullulan biosynthetic process	P	The chemical reactions and pathways resulting in the formation of pullulan, a neutral linear polysaccharide composed of repeating units of maltotriose joined by alpha-(1,6)-linkages.
51678	pullulan catabolic process	P	The chemical reactions and pathways resulting in the breakdown of pullulan, a neutral linear polysaccharide composed of repeating units of maltotriose joined by alpha-(1,6)-linkages.
51679	6-alpha-maltosylglucose metabolic process	P	The chemical reactions and pathways involving 6-alpha-maltosylglucose, also known as isopanose.
51680	6-alpha-maltosylglucose biosynthetic process	P	The chemical reactions and pathways resulting in the formation of 6-alpha-maltosylglucose, also known as isopanose.
51681	6-alpha-maltosylglucose catabolic process	P	The chemical reactions and pathways resulting in the breakdown of 6-alpha-maltosylglucose, also known as isopanose.
51682	galactomannan catabolic process	P	The chemical reactions and pathways resulting in the breakdown of galactomannan, a polysaccharide composed of D-galactosyl and D-mannosyl. The mannosyl units form the backbone structure (a linear main chain) with the D-galactosyl as single side units.
51683	establishment of Golgi localization	P	The directed movement of the Golgi to a specific location.
51684	maintenance of Golgi location	P	Any process in which the Golgi is maintained in a specific location within a cell and prevented from moving elsewhere.
51685	maintenance of ER location	P	Any process in which the endoplasmic reticulum is maintained in a specific location within a cell and prevented from moving elsewhere.
51686	establishment of ER localization	P	The directed movement of the endoplasmic reticulum to a specific location.
51687	maintenance of spindle location	P	Any process in which the spindle is maintained in a specific location within a cell and prevented from moving elsewhere.
51688	maintenance of plastid location	P	Any process in which a plastid is maintained in a specific location within a cell and prevented from moving elsewhere.
51689	multicellular organismal oligosaccharide catabolic process	P	The chemical reactions and pathways resulting in the breakdown of oligosaccharides, molecules with between two and (about) 20 monosaccharide residues connected by glycosidic linkages, in multicellular organisms, occurring at the tissue, organ, or organismal level.
51690	multicellular organismal oligosaccharide metabolic process	P	The chemical reactions and pathways involving oligosaccharides, molecules with between two and (about) 20 monosaccharide residues connected by glycosidic linkages, in multicellular organisms, occurring at the tissue, organ, or organismal level.
51691	cellular oligosaccharide metabolic process	P	The chemical reactions and pathways involving oligosaccharides, molecules with between two and (about) 20 monosaccharide residues connected by glycosidic linkages, as carried out by individual cells.
51692	cellular oligosaccharide catabolic process	P	The chemical reactions and pathways resulting in the breakdown of oligosaccharides, molecules with between two and (about) 20 monosaccharide residues connected by glycosidic linkages, as carried out by individual cells.
51693	actin filament capping	P	The binding of a protein or protein complex to the end of an actin filament, thus preventing the addition, exchange or removal of further actin subunits.
51694	pointed-end actin filament capping	P	The binding of a protein or protein complex to the pointed (or minus) end of an actin filament, thus preventing the addition, exchange or removal of further actin subunits.
51695	actin filament uncapping	P	The removal of capping protein from the end of actin filaments to free the ends for addition, exchange or removal of further actin subunits.
51696	pointed-end actin filament uncapping	P	The removal of capping protein from the pointed (or minus) end of actin filaments to free the ends for addition, exchange or removal of further actin subunits.
51697	protein delipidation	P	The breakage of covalent bonds to detach lipid groups from a protein.
51698	saccharopine oxidase activity	F	Catalysis of the reaction: L-saccharopine + O2 = L-2-aminoadipic 6-semialdehyde + L-glutamate + H2O2.
51699	proline oxidase activity	F	Catalysis of the reaction: L-proline + O2 + H2O = L-delta1-pyrroline-5-carboxylate + H2O2.
51700	fructosyl-amino acid oxidase activity	F	Catalysis of the reaction: fructosyl-amino acid + O2 = corresponding amino acid + glucosone + H2O2.
51701	interaction with host	P	An interaction between two organisms living together in more or less intimate association. The term host is used for the larger (macro) of the two members of a symbiosis; the various forms of symbiosis include parasitism, commensalism and mutualism.
51702	interaction with symbiont	P	An interaction between two organisms living together in more or less intimate association. The term symbiont is used for the smaller (macro) of the two members of a symbiosis; the various forms of symbiosis include parasitism, commensalism and mutualism.
51703	intraspecies interaction between organisms	P	Any process in which an organism has an effect on an organism of the same species.
51704	multi-organism process	P	A biological process which involves another organism of the same or different species.
51705	multi-organism behavior	P	Any process in which an organism has a behavioral effect on another organism of the same or different species.
51707	response to other organism	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from another living organism.
51708	intracellular protein transport in other organism involved in symbiotic interaction	P	The directed movement of an organism's proteins within a cell of a second organism, where the two organisms are in a symbiotic interaction.
51709	regulation of killing of cells of other organism	P	Any process that modulates the frequency, rate or extent of the killing by an organism of cells in another organism.
51710	regulation of cytolysis in other organism	P	Any process that modulates the frequency, rate or extent of the cytolysis by an organism of cells in another organism.
51711	negative regulation of killing of cells of other organism	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the killing by an organism of cells in another organism.
51712	positive regulation of killing of cells of other organism	P	Any process that activates or increases the frequency, rate or extent of the killing by an organism of cells in another organism.
51713	negative regulation of cytolysis in other organism	P	Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of the cytolysis of cells in another organism.
51714	positive regulation of cytolysis in other organism	P	Any process that activates or increases the frequency, rate or extent of the cytolysis by an organism of cells in another organism.
51715	cytolysis in other organism	P	The killing by an organism of a cell in another organism by means of the rupture of cell membranes and the loss of cytoplasm.
51716	cellular response to stimulus	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus. The process begins with detection of the stimulus by a cell and ends with a change in state or activity or the cell.
51717	inositol-1,3,4,5-tetrakisphosphate 3-phosphatase activity	F	Catalysis of the reaction: inositol-1,3,4,5-tetrakisphosphate + H2O = inositol-1,4,5-trisphosphate + phosphate.
51718	DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates	F	Catalysis of the reaction: S-adenosyl-L-methionine + CpG (in DNA) = S-adenosyl-L-homocysteine + 5-MeCpG (in DNA).
51719	DNA (cytosine-5-)-methyltransferase activity, acting on CpN substrates	F	Catalysis of the reaction: S-adenosyl-L-methionine + DNA containing CpN = S-adenosyl-L-homocysteine + DNA containing 5-MeCpN.
51720	DNA (cytosine-5-)-methyltransferase activity, acting on CpNpG substrates	F	Catalysis of the reaction: S-adenosyl-L-methionine + DNA containing CpNpG = S-adenosyl-L-homocysteine + DNA containing 5-MeCpNpG.
51721	protein phosphatase 2A binding	F	Interacting selectively and non-covalently with the enzyme protein phosphatase 2A.
51722	protein C-terminal methylesterase activity	F	Catalysis of the reaction: C-terminal protein amino acid methyl ester + H2O = protein amino acid + methanol.
51723	protein methylesterase activity	F	Catalysis of the reaction: protein amino acid methyl ester + H2O = protein amino acid + methanol.
51724	NAD transporter activity	F	Enables the directed movement of nicotinamide adenine dinucleotide into, out of or within a cell, or between cells; transport may be of either the oxidized form, NAD, or the reduced form, NADH.
51725	protein de-ADP-ribosylation	P	The process of removing one or more ADP-ribose residues from a protein.
51726	regulation of cell cycle	P	Any process that modulates the rate or extent of progression through the cell cycle.
51728	cell cycle switching, mitotic to meiotic cell cycle	P	The process in which a cell switches cell cycle mode from mitotic to meiotic division.
51729	germline cell cycle switching, mitotic to meiotic cell cycle	P	The process in which a germline cell switches cell cycle mode from mitotic to meiotic division.
51730	GTP-dependent polyribonucleotide 5'-hydroxyl-kinase activity	F	Catalysis of the reaction: GTP + 5'-dephospho-RNA = GDP + 5'-phospho-RNA.
51731	polynucleotide 5'-hydroxyl-kinase activity	F	Catalysis of the reaction: NTP + 5'-dephosphopolynucleotide = NDP + 5'-phosphopolynucleotide. The polynucleotide may be DNA or RNA.
51732	polyribonucleotide kinase activity	F	Catalysis of the reaction: NTP + 5'-dephospho-RNA = NDP + 5'-phospho-RNA.
51733	polydeoxyribonucleotide kinase activity	F	Catalysis of the reaction: NTP + 5'-dephospho-DNA = NDP + 5'-phospho-DNA.
51734	ATP-dependent polynucleotide kinase activity	F	Catalysis of the reaction: ATP + 5'-dephosphopolynucleotide = ADP + 5'-phosphopolynucleotide. The polynucleotide may be DNA or RNA.
51735	GTP-dependent polynucleotide kinase activity	F	Catalysis of the reaction: GTP + 5'-dephosphopolynucleotide = GDP + 5'-phosphopolynucleotide. The polynucleotide may be DNA or RNA.
51736	ATP-dependent polyribonucleotide 5'-hydroxyl-kinase activity	F	Catalysis of the reaction: ATP + 5'-dephospho-RNA = ADP + 5'-phospho-RNA.
51737	GTP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity	F	Catalysis of the reaction: GTP + 5'-dephospho-DNA = GDP + 5'-phospho-DNA.
51738	xanthophyll binding	F	Interacting selectively and non-covalently with xanthophylls, any of several neutral yellow to orange carotenoid pigments containing oxygen.
51740	ethylene binding	F	Interacting selectively and non-covalently with ethylene (C2-H4, ethene), a simple hydrocarbon gas that can function in plants as a growth regulator.
51741	2-methyl-6-phytyl-1,4-benzoquinone methyltransferase activity	F	Catalysis of the reaction: 2-methyl-6-phytyl-1,4-benzoquinone + S-adenosyl-methionine = 2,3-dimethyl-6-phytyl-1,4-benzoquinone + S-adenosyl-homocysteine.
51742	2-methyl-6-solanyl-1,4-benzoquinone methyltransferase activity	F	Catalysis of the reaction: 2-methyl-6-solanyl-1,4-benzoquinone + S-adenosyl-methionine = 2,3-dimethyl-6-solanyl-1,4-benzoquinone + S-adenosyl-homocysteine.
51743	red chlorophyll catabolite reductase activity	F	Catalysis of the reaction: red chlorophyll catabolite + reduced ferredoxin + 2 H+ = primary fluorescent catabolite + oxidized ferredoxin. This reaction is the reduction of the C20/C1 double bond in the pyrrole system of red chlorophyll catabolite (RCC) to a colorless tetrapyrrole (pFCC) with a strong blue fluorescence.
51744	3,8-divinyl protochlorophyllide a 8-vinyl reductase activity	F	Catalysis of the reaction: divinyl protochlorophyllide a + NADPH + H+ = monovinyl protochlorophyllide a + NADP+.
51745	4-hydroxy-3-methylbut-2-en-1-yl diphosphate reductase activity	F	Catalysis of the reaction: (E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate + NAD(P)H + H+ = isopentenyl diphosphate + NAD(P)+ + H2O. Note that (E)-4-hydroxy-3-methylbut-2-en-1-yl diphosphate is an alternative name for 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate.
51746	thalianol synthase activity	F	Catalysis of the cyclization of 3(S)-oxidosqualene to (3S,13S,14R)-malabarica-8,17,21-trien-3-ol (thalianol).
51747	cytosine C-5 DNA demethylase activity	F	Catalysis of the reaction: methyl-dCpdG DNA + H2O = dCpdG DNA + methanol. This reaction is the hydrolytic removal of the methyl group on the 5 position of cytosine in DNA.
51748	UTP-monosaccharide-1-phosphate uridylyltransferase activity	F	Catalysis of the reaction: UTP + a monosaccharide 1-phosphate = diphosphate + UDP-monosaccharide.
51749	indole acetic acid carboxyl methyltransferase activity	F	Catalysis of the reaction: indole acetic acid + S-adenosyl-methionine = methyl indole acetic acid ester + S-adenosyl-homocysteine.
51750	delta3,5-delta2,4-dienoyl-CoA isomerase activity	F	Catalysis of the isomerization of 3,5-dienoyl-CoA to 2,4-dienoyl-CoA.
51751	alpha-1,4-mannosyltransferase activity	F	Catalysis of the transfer of a mannose residue to an oligosaccharide, forming an alpha-(1->4) linkage.
51752	phosphoglucan, water dikinase activity	F	Catalysis of the reaction: ATP + [phospho-alpha-glucan] + H2O = AMP + O-phospho-[phospho-alpha-glucan] + phosphate.
51753	mannan synthase activity	F	Catalysis of the reaction: mannan(n) + GDP-mannose = mannan(n+1) + GDP. This reaction is the formation of the beta-(1->4)-linked mannan backbone in substrates such as galactomannan.
51754	meiotic sister chromatid cohesion, centromeric	P	The cell cycle process in which centromeres of sister chromatids are joined during meiosis.
51755	meiotic sister chromatid arm separation	P	The cell cycle process in which sister chromatid arms are physically detached from each other during meiosis.
51756	meiotic sister chromatid centromere separation	P	The cell cycle process in which the centromeres of sister chromatids are physically detached from each other during meiosis.
51757	meiotic sister chromatid separation	P	The process in which sister chromatids are physically detached from each other during meiosis.
51758	homologous chromosome movement towards spindle pole involved in homologous chromosome segregation	P	The directed movement of homologous chromosomes from the center of the spindle towards the spindle poles, mediated by the shortening of microtubules attached to the chromosomes, that contributes to meiosis I.
51759	sister chromosome movement towards spindle pole involved in meiotic sister chromatid segregation	P	The directed movement of sister chromosomes from the center of the spindle towards the spindle poles, mediated by the shortening of microtubules attached to the chromosomes, during meiosis II.
51760	meiotic sister chromatid cohesion, arms	P	The cell cycle process in which the sister chromatids of a replicated chromosome are joined along the length of the chromosome arms during meiosis.
51761	sesquiterpene metabolic process	P	The chemical reactions and pathways involving sesquiterpenes, any of a class of terpenes of the formula C15H24 or a derivative of such a terpene.
51762	sesquiterpene biosynthetic process	P	The chemical reactions and pathways resulting in the formation of sesquiterpenes, any of a class of terpenes of the formula C15H24 or a derivative of such a terpene.
51763	sesquiterpene catabolic process	P	The chemical reactions and pathways resulting in the breakdown of sesquiterpenes, any of a class of terpenes of the formula C15H24 or a derivative of such a terpene.
51764	actin crosslink formation	P	The process in which two or more actin filaments are connected together by proteins that act as crosslinks between the filaments. The crosslinked filaments may be on the same or differing axes.
51765	inositol tetrakisphosphate kinase activity	F	Catalysis of the reaction: inositol tetrakisphosphate + ATP = inositol pentakisphosphate + ADP.
51766	inositol trisphosphate kinase activity	F	Catalysis of the reaction: inositol trisphosphate + ATP = inositol tetrakisphosphate + ADP.
51767	nitric-oxide synthase biosynthetic process	P	The chemical reactions and pathways resulting in the formation of a nitric-oxide synthase, an enzyme which catalyzes the reaction L-arginine + n NADPH + n H+ + m O2 = citrulline + nitric oxide + n NADP+.
51769	regulation of nitric-oxide synthase biosynthetic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of a nitric-oxide synthase enzyme.
51770	positive regulation of nitric-oxide synthase biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of a nitric oxide synthase enzyme.
51771	negative regulation of nitric-oxide synthase biosynthetic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of a nitric-oxide synthase enzyme.
51775	response to redox state	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating redox state. Redox state refers to the balance of oxidized versus reduced forms of electron donors and acceptors in an organelle, cell or organ; plastoquinone, glutathione (GSH/GSSG), and nicotinamide nucleotides (NAD+/NADH and NADP+/NADPH) are among the most important.
51776	detection of redox state	P	The series of events in which a chemical stimulus indicating redox state is received and converted into a molecular signal. Redox state refers to the balance of oxidized versus reduced forms of electron donors and acceptors in an organelle, cell or organ; plastoquinone, glutathione (GSH/GSSG), and nicotinamide nucleotides (NAD+/NADH and NADP+/NADPH) are among the most important.
51777	ent-kaurenoate oxidase activity	F	Catalysis of the reaction: ent-kaurenoate + NADPH + O2 = ent-7-alpha-hydroxykaurenoate + NADP+ + H2O. This is the first of three successive reactions resulting in the oxidation of ent-kaurenoate (ent-kaurenoic acid) to gibberellin 12 (GA12).
51778	ent-7-alpha-hydroxykaurenoate oxidase activity	F	Catalysis of the reaction: ent-7-alpha-hydroxykaurenoate + NADPH + H+ + O2 = gibberellin 12-aldehyde + NADP+ + 2 H2O. This is the second of three successive reactions resulting in the oxidation of ent-kaurenoate (ent-kaurenoic acid) to gibberellin 12 (GA12).
51779	gibberellin 12-aldehyde oxidase activity	F	Catalysis of the reaction: gibberellin 12-aldehyde + NADPH + H+ + O2 = gibberellin 12 + NADP+ + H2O. This is the third of three successive reactions resulting in the oxidation of ent-kaurenoate (ent-kaurenoic acid) to gibberellin 12 (GA12).
51780	behavioral response to nutrient	P	Any process that results in a change in the behavior of an organism as a result of a nutrient stimulus.
51781	positive regulation of cell division	P	Any process that activates or increases the frequency, rate or extent of cell division.
51782	negative regulation of cell division	P	Any process that stops, prevents, or reduces the frequency, rate or extent of cell division.
51783	regulation of nuclear division	P	Any process that modulates the frequency, rate or extent of nuclear division, the partitioning of the nucleus and its genetic information.
51784	negative regulation of nuclear division	P	Any process that stops, prevents, or reduces the frequency, rate or extent of nuclear division, the partitioning of the nucleus and its genetic information.
51785	positive regulation of nuclear division	P	Any process that activates or increases the frequency, rate or extent of nuclear division, the partitioning of the nucleus and its genetic information.
51786	all-trans-retinol 13,14-reductase activity	F	Catalysis of the reaction: all-trans-13,14-dihydroretinol + A = all-trans-retinol + AH(2). Note that this reaction has only been observed to occur in the opposite direction.
51787	misfolded protein binding	F	Interacting selectively and non-covalently with a misfolded protein.
51788	response to misfolded protein	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a misfolded protein stimulus.
51790	short-chain fatty acid biosynthetic process	P	The chemical reactions and pathways resulting in the formation of fatty acids with a chain length of less than C6.
51791	medium-chain fatty acid metabolic process	P	The chemical reactions and pathways involving medium-chain fatty acids, any fatty acid with a chain length of between C6 and C12.
51792	medium-chain fatty acid biosynthetic process	P	The chemical reactions and pathways resulting in the formation of any fatty acid with a chain length of between C6 and C12.
51793	medium-chain fatty acid catabolic process	P	The chemical reactions and pathways resulting in the breakdown of any fatty acid with a chain length of between C6 and C12.
51794	regulation of catagen	P	Any process that modulates the frequency, rate or extent of catagen, the regression phase of the hair cycle.
51795	positive regulation of catagen	P	Any process that activates or increases the frequency, rate or extent of catagen, the regression phase of the hair cycle.
51796	negative regulation of catagen	P	Any process that stops, prevents, or reduces the frequency, rate or extent of catagen, the regression phase of the hair cycle.
51797	regulation of hair follicle development	P	Any process that modulates the frequency, rate or extent of hair follicle development.
51798	positive regulation of hair follicle development	P	Any process that activates or increases the frequency, rate or extent of hair follicle development.
51799	negative regulation of hair follicle development	P	Any process that stops, prevents, or reduces the frequency, rate or extent of hair follicle development.
51800	phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity	F	Catalysis of the reaction: phosphatidylinositol-3,4-bisphosphate + H2O = phosphatidylinositol-4-phosphate + phosphate.
51801	cytolysis in other organism involved in symbiotic interaction	P	The killing by an organism of a cell in a second organism by means of the rupture of cell membranes and the loss of cytoplasm, where the two organisms are in a symbiotic interaction.
51802	regulation of cytolysis in other organism involved in symbiotic interaction	P	Any process in which an organism modulates the frequency, rate or extent of the cytolysis by that organism of cells in a second organism, where the two organisms are in a symbiotic interaction.
51803	negative regulation of cytolysis in other organism involved in symbiotic interaction	P	Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of cytolysis by that organism of cells in a second organism, where the two organisms are in a symbiotic interaction.
51804	positive regulation of cytolysis in other organism involved in symbiotic interaction	P	Any process in which an organism activates or increases the frequency, rate or extent of cytolysis by that organism of cells in a second organism, where the two organisms are in a symbiotic interaction.
51805	evasion or tolerance of immune response of other organism involved in symbiotic interaction	P	Any process in which an organism avoids the immune response of a second organism, where the two organisms are in a symbiotic interaction.
51806	entry into cell of other organism involved in symbiotic interaction	P	The invasion by an organism of a cell of a second organism, where the two organisms are in a symbiotic interaction.
51807	evasion or tolerance of defense response of other organism involved in symbiotic interaction	P	Any process, either active or passive, by which an organism avoids or tolerates the effects of a second organism's defense response; the defense response is mounted by the second organism in response to the presence of the first organism, where the two organisms are in a symbiotic interaction.
51808	translocation of peptides or proteins into other organism involved in symbiotic interaction	P	The directed movement of peptides or proteins produced by an organism to a location inside a second organism, where the two organisms are in a symbiotic interaction.
51809	passive evasion of immune response of other organism involved in symbiotic interaction	P	Any process in which an organism avoids the immune response of a second organism without directly interfering with the second organism's immune system, where the two organisms are in a symbiotic interaction.
51810	active evasion of immune response of other organism involved in symbiotic interaction	P	Any process in which an organism avoids the immune response of a second organism which directly affects the second organism's immune system, where the two organisms are in a symbiotic interaction.
51811	active evasion of immune response of other organism via regulation of complement system of other organism involved in symbiotic interaction	P	Any process in which an organism avoids the immune response of a second organism by regulating the second organism's complement system, where the two organisms are in a symbiotic interaction.
51812	active evasion of immune response of other organism via regulation of cytokine network of other organism involved in symbiotic interaction	P	Any process in which an organism avoids the immune response of a second organism by regulating the second organism's cytokine networks, where the two organisms are in a symbiotic interaction.
51813	active evasion of immune response of other organism via regulation of antigen processing and presentation in other organism involved in symbiotic interaction	P	Any process in which an organism avoids the immune response of a second organism by regulating the second organism's antigen processing or presentation pathways, where the two organisms are in a symbiotic interaction.
51814	movement in other organism involved in symbiotic interaction	P	The process in which an organism or its progeny spreads from one location to another within a second organism, where the two organisms are in a symbiotic interaction.
51815	migration in other organism involved in symbiotic interaction	P	The directional movement of an organism from one place to another within a second organism, where the two organisms are in a symbiotic interaction.
51816	acquisition of nutrients from other organism during symbiotic interaction	P	The production of structures and/or molecules in an organism that are required for the acquisition and/or utilization of nutrients obtained from a second organism, where the two organisms are in a symbiotic interaction.
51817	modification of morphology or physiology of other organism involved in symbiotic interaction	P	The process in which an organism effects a change in the structure or processes of a second organism, where the two organisms are in a symbiotic interaction.
51818	disruption of cells of other organism involved in symbiotic interaction	P	A process in which an organism has a negative effect on the functioning of the second organism's cells, where the two organisms are in a symbiotic interaction.
51819	induction of tumor, nodule, or growth in other organism involved in symbiotic interaction	P	The process in which an organism causes the formation of a mass of cells in a second organism, where the two organisms are in a symbiotic interaction.
51820	induction of tumor, nodule, or growth containing transformed cells in other organism involved in symbiotic interaction	P	The process in which an organism causes the formation in a second organism of a growth whose cells have been transformed and continue to exist in the absence of the first organism, where the two organisms are in a symbiotic interaction.
51821	dissemination or transmission of organism from other organism involved in symbiotic interaction	P	The movement of an organism from a second organism to another place in the environment, where the two organisms are in a symbiotic interaction. The first organism may also move to a different organism.
51822	dissemination or transmission of organism from other organism by vector involved in symbiotic interaction	P	The movement of an organism from a second organism to another place in the environment by means of a vector, where the two organisms are in a symbiotic interaction. The first organism may also move to a different organism, and the vector organism is often an insect or an animal.
51823	regulation of synapse structural plasticity	P	Any process that modulates the frequency, rate or extent of synapse structural plasticity. Synapse structural plasticity is a type of cytoskeletal remodeling; this remodeling is induced by stimuli that can lead to long term potentiation and it can be activity-dependent or -independent. Examples of cytoskeletal changes include the formation of new spines and increase in spine size; this can be accompanied by the insertion of greater numbers of glutamate (or other neurotransmitter) receptors into the post-synaptic membrane.
51824	recognition of other organism involved in symbiotic interaction	P	The set of specific processes that allow an organism to detect the presence of a second organism via physical or chemical signals, where the two organisms are in a symbiotic interaction.
51826	negative regulation of synapse structural plasticity	P	Any process that stops, prevents, or reduces the frequency, rate or extent of synapse structural plasticity.
51828	entry into other organism involved in symbiotic interaction	P	Penetration by an organism into the body, tissues, or cells of a second organism, where the two organisms are in a symbiotic interaction.
51829	entry into other organism through natural portals involved in symbiotic interaction	P	Penetration by an organism into a second organism via naturally occurring openings in the second organism, where the two organisms are in a symbiotic interaction.
51830	entry into other organism through barriers of other organism involved in symbiotic interaction	P	Penetration by an organism into a second organism via active breaching of physical barriers, where the two organisms are in a symbiotic interaction.
51832	avoidance of defenses of other organism involved in symbiotic interaction	P	Any process, either constitutive or induced, by which an organism evades, minimizes, or suppresses the effects of a second organism's defense(s), where the two organisms are in a symbiotic interaction.
51833	suppression of defenses of other organism involved in symbiotic interaction	P	Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of the defense(s) of a second organism, where the two organisms are in a symbiotic interaction. Suppression occurs by active mechanisms that normally result in the shutting down of pathways in the second organism.
51834	evasion or tolerance of defenses of other organism involved in symbiotic interaction	P	Any process, either active or passive, by which an organism avoids or tolerates the effects of a second organism's defense(s), where the two organisms are in a symbiotic interaction. Defenses may be induced by the presence of the organism or may be preformed (e.g. physical barriers).
51835	positive regulation of synapse structural plasticity	P	Any process that activates, maintains or increases the frequency, rate or extent of synaptic structural plasticity.
51836	translocation of molecules into other organism involved in symbiotic interaction	P	The directed movement of a molecule(s) produced by an organism to a location inside a second organism, where the two organisms are in a symbiotic interaction.
51837	translocation of DNA into other organism involved in symbiotic interaction	P	The directed movement of DNA from an organism to a location inside a second organism, where the two organisms are in a symbiotic interaction.
51838	cytolysis by host of symbiont cells	P	The killing by an organism of a cell in its symbiont organism by means of the rupture of cell membranes and the loss of cytoplasm. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.
51839	regulation by host of cytolysis of symbiont cells	P	Any process in which an organism modulates the frequency, rate or extent of the cytolysis by that organism of cells in its symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.
51840	negative regulation by host of cytolysis of symbiont cells	P	Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of cytolysis by that organism of cells in its symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.
51841	positive regulation by host of cytolysis of symbiont cells	P	Any process in which an organism activates or increases the frequency, rate or extent of cytolysis by that organism of cells in its symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.
51844	translocation of peptides or proteins into symbiont	P	The directed movement of peptides or proteins produced by an organism to a location inside the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.
51850	acquisition of nutrients from symbiont	P	The production of structures and/or molecules in an organism that are required for the acquisition and/or utilization of nutrients obtained from its symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.
51851	modification by host of symbiont morphology or physiology	P	The process in which an organism effects a change in the structure or processes of a symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.
51852	disruption by host of symbiont cells	P	Any process in which an organism has a negative effect on the functioning of the symbiont's cells. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.
51855	recognition of symbiont	P	The set of specific processes that allow an organism to detect the presence of its symbiont via physical or chemical signals. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.
51858	avoidance of symbiont defenses	P	Any process, either constitutive or induced, by which an organism evades, minimizes, or suppresses the effects of its symbiont organism's defense(s). The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.
51859	suppression of symbiont defenses	P	Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of symbiont defense(s) by active mechanisms that normally result in the shutting down of a symbiont pathway. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.
51860	evasion or tolerance of symbiont defenses	P	The process, either active or passive, by which an organism evades or tolerates the effects of the defense(s) or defense molecules of a symbiont organism. Symbiont defenses may be induced by the presence of the organism or may be preformed (e.g. physical barriers). The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.
51861	glycolipid binding	F	Interacting selectively and non-covalently with a glycolipid, any compound containing one or more monosaccharide residues bound by a glycosidic linkage to a hydrophobic group such as an acylglycerol, a sphingoid, a ceramide (N-acylsphingoid) or a prenyl phosphate.
51862	translocation of molecules into symbiont	P	The directed movement of molecule(s) produced by an organism to a location inside the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.
51864	histone demethylase activity (H3-K36 specific)	F	Catalysis of the reaction: histone H3 N6-methyl-L-lysine (position 36) + alpha-ketoglutarate + O2 = succinate + CO2 + formaldehyde + lysine. This reaction is the removal of a methyl group from lysine at position 36 of the histone H3 protein.
51865	protein autoubiquitination	P	The ubiquitination by a protein of one or more of its own amino acid residues, or residues on an identical protein. Ubiquitination occurs on the lysine residue by formation of an isopeptide crosslink.
51866	general adaptation syndrome	P	General adaptation syndrome is the set of changes in various organ systems of the body, especially the pituitary-endocrine system, in response to a wide range of strong external stimuli, both physiological and psychological. It is described as having three stages: alarm reaction, where the body detects the external stimulus; adaptation, where the body engages defensive countermeasures against the stressor; and exhaustion, where the body begins to run out of defenses.
51867	general adaptation syndrome, behavioral process	P	The set of behavioral processes that occur as part of the general adaptation syndrome, the response of the body to a strong, stressful stimulus.
51870	methotrexate binding	F	Interacting selectively and non-covalently with methotrexate, an antineoplastic antimetabolite with immunosuppressant properties. It is an inhibitor of tetrahydrofolate reductase and prevents the formation of tetrahydrofolate, necessary for synthesis of thymidylate, an essential component of DNA.
51871	dihydrofolic acid binding	F	Interacting selectively and non-covalently with dihydrofolic acid, a folic acid in which the bicyclic pteridine structure is in the dihydro, partially reduced form; they are intermediates in folate metabolism and are reduced to their tetrahydro, reduced forms.
51872	sphingosine catabolic process	P	The chemical reactions and pathways resulting in the breakdown of sphingosine (sphing-4-enine), trans-D-erytho-2-amino-octadec-4-ene-1,3-diol, a long chain amino diol sphingoid base that occurs in most sphingolipids in animal tissues.
51873	killing by host of symbiont cells	P	Any process mediated by an organism that results in the death of cells in the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.
51874	sphinganine-1-phosphate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of sphinganine-1-phosphate, the phosphorylated derivative of D-erythro-2-amino-1,3-octadecanediol.
51875	pigment granule localization	P	Any process in which a pigment granule is transported to, and/or maintained in, a specific location within the cell.
51876	pigment granule dispersal	P	The directed movement of pigment granules within a cell towards the cell periphery.
51877	pigment granule aggregation in cell center	P	The directed movement of dispersed pigment granules towards the center of the cell.
51878	lateral element assembly	P	The cell cycle process in which lateral elements are formed. Axial elements form a proteinaceous core between the two sister chromatids of each chromosome; the two axial elements then connect along their entire lengths by fine fibers known as transverse filaments, forming the lateral elements.
51879	Hsp90 protein binding	F	Interacting selectively and non-covalently with Hsp90 proteins, any of a group of heat shock proteins around 90kDa in size.
51880	G-quadruplex DNA binding	F	Interacting selectively and non-covalently with G-quadruplex DNA structures, in which groups of four guanines adopt a flat, cyclic Hoogsteen hydrogen-bonding arrangement known as a guanine tetrad. The stacking of guanine tetrads results in G-quadruplex DNA structures. G-quadruplex DNA can form under physiological conditions from some G-rich sequences, such as those found in telomeres, immunoglobulin switch regions, gene promoters, fragile X repeats, and the dimerization domain in the human immunodeficiency virus (HIV) genome.
51881	regulation of mitochondrial membrane potential	P	Any process that modulates the establishment or extent of the mitochondrial membrane potential, the electric potential existing across the mitochondrial membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane.
51882	mitochondrial depolarization	P	The process in which the potential difference across the mitochondrial membrane is reduced from its steady state level.
51883	killing of cells in other organism involved in symbiotic interaction	P	Any process mediated by an organism that results in the death of cells in a second organism, where the two organisms are in a symbiotic interaction.
51884	regulation of anagen	P	Any process that modulates the frequency, rate or extent of anagen, the growth phase of the hair cycle.
51885	positive regulation of anagen	P	Any process that activates or increases the frequency, rate or extent of anagen, the growth phase of the hair cycle.
51886	negative regulation of anagen	P	Any process that stops, prevents, or reduces the frequency, rate or extent of anagen, the growth phase of the hair cycle.
51887	regulation of exogen	P	Any process that modulates the frequency, rate or extent of exogen, the shedding phase of the hair cycle.
51888	positive regulation of exogen	P	Any process that activates or increases the frequency, rate or extent of exogen, the shedding phase of the hair cycle.
51889	negative regulation of exogen	P	Any process that stops, prevents, or reduces the frequency, rate or extent of exogen, the shedding phase of the hair cycle.
51890	regulation of cardioblast differentiation	P	Any process that modulates the frequency, rate or extent of cardioblast differentiation, the process in which a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.
51891	positive regulation of cardioblast differentiation	P	Any process that activates or increases the frequency, rate or extent of cardioblast differentiation, the process in which a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.
51892	negative regulation of cardioblast differentiation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of cardioblast differentiation, the process in which a relatively unspecialized mesodermal cell acquires the specialized structural and/or functional features of a cardioblast. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.
51893	regulation of focal adhesion assembly	P	Any process that modulates the frequency, rate or extent of focal adhesion formation, the establishment and maturation of focal adhesions.
51894	positive regulation of focal adhesion assembly	P	Any process that activates or increases the frequency, rate or extent of focal adhesion assembly, the establishment and maturation of focal adhesions.
51895	negative regulation of focal adhesion assembly	P	Any process that stops, prevents, or reduces the frequency, rate or extent of focal adhesion assembly, the establishment and maturation of focal adhesions.
51896	regulation of protein kinase B signaling	P	Any process that modulates the frequency, rate or extent of protein kinase B signaling, a series of reactions mediated by the intracellular serine/threonine kinase protein kinase B.
51897	positive regulation of protein kinase B signaling	P	Any process that activates or increases the frequency, rate or extent of protein kinase B signaling, a series of reactions mediated by the intracellular serine/threonine kinase protein kinase B.
51898	negative regulation of protein kinase B signaling	P	Any process that stops, prevents, or reduces the frequency, rate or extent of protein kinase B signaling, a series of reactions mediated by the intracellular serine/threonine kinase protein kinase B.
51899	membrane depolarization	P	The process in which membrane potential decreases with respect to its steady-state potential, usually from negative potential to a more positive potential. For example, the initial depolarization during the rising phase of an action potential is in the direction from the negative steady-state resting potential towards the positive membrane potential that will be the peak of the action potential.
51900	regulation of mitochondrial depolarization	P	Any process that modulates the frequency, rate or extent of the change in the membrane potential of the mitochondria from negative to positive.
51901	positive regulation of mitochondrial depolarization	P	Any process that activates, maintains or increases the frequency, rate or extent of the change in the membrane potential of the mitochondria from negative to positive.
51902	negative regulation of mitochondrial depolarization	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the change in the membrane potential of the mitochondria from negative to positive.
51903	S-(hydroxymethyl)glutathione dehydrogenase activity	F	Catalysis of the reaction: S-(hydroxymethyl)glutathione + NAD(P)+ = S-formylglutathione + NAD(P)H + H+.
51904	pigment granule transport	P	The directed movement of pigment granules into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
51905	establishment of pigment granule localization	P	The directed movement of a pigment granule to a specific location.
51906	maintenance of pigment granule location	P	Any process in which a pigment granule is maintained in a location and prevented from moving elsewhere.
51907	S-(hydroxymethyl)glutathione synthase activity	F	Catalysis of the reaction: S-(hydroxymethyl)glutathione = formaldehyde + glutathione.
51908	double-stranded DNA 5'-3' exodeoxyribonuclease activity	F	Catalysis of the sequential cleavage of mononucleotides from a free 5' terminus of a double-stranded DNA molecule.
51909	acetylenecarboxylate hydratase activity, producing 3-hydroxypropenoate	F	Catalysis of the reaction: 3-hydroxypropenoate = propynoate + H2O.
51911	Methanosarcina-phenazine hydrogenase activity	F	Catalysis of the reaction: H2 + 2-(2,3-dihydropentaprenyloxy)phenazine = 2-dihydropentaprenyloxyphenazine.
51912	CoB--CoM heterodisulfide reductase activity	F	Catalysis of the reaction: coenzyme B + coenzyme M + methanophenazine = N-{7-[(2-sulfoethyl)dithio]heptanoyl}-3-O-phospho-L-threonine + dihydromethanophenazine.
51913	regulation of synaptic plasticity by chemical substance	P	The process in which a chemical substance modulates synaptic plasticity, the ability of synapses to change as circumstances require.
51914	positive regulation of synaptic plasticity by chemical substance	P	The process in which a chemical substance increases synaptic plasticity, the ability of synapses to change as circumstances require.
51915	induction of synaptic plasticity by chemical substance	P	The process in which a chemical substance activates synaptic plasticity, the ability of synapses to change as circumstances require.
51916	granulocyte colony-stimulating factor binding	F	Interacting selectively and non-covalently with granulocyte colony-stimulating factor, G-CSF.
51917	regulation of fibrinolysis	P	Any process that modulates the frequency, rate or extent of fibrinolysis, an ongoing process that solubilizes fibrin, resulting in the removal of small blood clots.
51918	negative regulation of fibrinolysis	P	Any process that stops, prevents, or reduces the frequency, rate or extent of fibrinolysis, an ongoing process that solubilizes fibrin, resulting in the removal of small blood clots.
51919	positive regulation of fibrinolysis	P	Any process that activates, maintains or increases the frequency, rate or extent of fibrinolysis, an ongoing process that solubilizes fibrin, resulting in the removal of small blood clots.
51920	peroxiredoxin activity	F	Catalysis of the reaction: 2 R'-SH + ROOH = R'-S-S-R' + H2O + ROH.
51921	adenosylcobyric acid synthase (glutamine-hydrolyzing) activity	F	Catalysis of the reaction: 4 L-glutamine + adenosylcob(III)yrinate a,c-diamide + 4 ATP + 4 H(2)O = 4 L-glutamate + adenosylcobyrate + 4 ADP + 8 H(+) + 4 phosphate.
51922	cholesterol sulfotransferase activity	F	Catalysis of the reaction: 3'-phosphoadenosine 5'-phosphosulfate + cholesterol = adenosine 3',5'-bisphosphate + cholesterol sulfate.
51923	sulfation	P	The addition of a sulfate group to a molecule.
51924	regulation of calcium ion transport	P	Any process that modulates the frequency, rate or extent of the directed movement of calcium ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
51926	negative regulation of calcium ion transport	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of calcium ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
51928	positive regulation of calcium ion transport	P	Any process that activates or increases the frequency, rate or extent of the directed movement of calcium ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
51930	regulation of sensory perception of pain	P	Any process that modulates the frequency, rate or extent of the sensory perception of pain, the series of events required for an organism to receive a painful stimulus, convert it to a molecular signal, and recognize and characterize the signal.
51931	regulation of sensory perception	P	Any process that modulates the frequency, rate or extent of sensory perception, the series of events required for an organism to receive a sensory stimulus, convert it to a molecular signal, and recognize and characterize the signal.
51932	synaptic transmission, GABAergic	P	The process of communication from a neuron to another neuron across a synapse using the neurotransmitter gamma-aminobutyric acid (GABA).
51933	amino acid neurotransmitter reuptake	P	The uptake of amino acid neurotransmitters by neurons or glial cells. This process leads to inactivation and recycling of neurotransmitters.
51934	catecholamine uptake involved in synaptic transmission	P	The uptake of catecholamine neurotransmitters by neurons or glial cells. This process leads to inactivation and recycling of neurotransmitters.
51935	glutamate reuptake	P	The uptake of L-glutamate by neurons or glial cells. This process leads to inactivation and recycling of neurotransmitters.
51936	gamma-aminobutyric acid reuptake	P	The uptake of gamma-aminobutyric acid (GABA, 4-aminobutyrate) by neurons or glial cells. This process leads to inactivation and recycling of neurotransmitters.
51937	catecholamine transport	P	The directed movement of catecholamines, a group of physiologically important biogenic amines that possess a catechol (3,4-dihydroxyphenyl) nucleus and are derivatives of 3,4-dihydroxyphenylethylamine.
51938	L-glutamate import	P	The directed movement of L-glutamate, the L-enantiomer of the anion of 2-aminopentanedioic acid, into a cell or organelle.
51939	gamma-aminobutyric acid import	P	The directed movement of gamma-aminobutyric acid (GABA, 4-aminobutyrate) into a cell or organelle.
51940	regulation of catecholamine uptake involved in synaptic transmission	P	Any process that modulates the frequency, rate or extent of the directed movement of catecholamine neurotransmitters into a neuron or glial cell.
51941	regulation of amino acid uptake involved in synaptic transmission	P	Any process that modulates the frequency, rate or extent of the directed movement of amino acid neurotransmitters into a neuron or glial cell.
51942	negative regulation of amino acid uptake involved in synaptic transmission	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of amino acid neurotransmitters into a neuron or glial cell.
51943	positive regulation of amino acid uptake involved in synaptic transmission	P	Any process that activates, maintains or increases the frequency, rate or extent of the directed movement of amino acid neurotransmitters into a neuron or glial cell.
51944	positive regulation of catecholamine uptake involved in synaptic transmission	P	Any process that activates, maintains or increases the frequency, rate or extent of the directed movement of catecholamine neurotransmitters into a neuron or glial cell.
51945	negative regulation of catecholamine uptake involved in synaptic transmission	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of catecholamine neurotransmitters into a neuron or glial cell.
51946	regulation of glutamate uptake involved in transmission of nerve impulse	P	Any process that modulates the frequency, rate or extent of the directed movement of L-glutamate into a neuron or glial cell.
51947	regulation of gamma-aminobutyric acid uptake involved in transmission of nerve impulse	P	Any process that modulates the frequency, rate or extent of the directed movement of gamma-aminobutyric acid (GABA, 4-aminobutyrate) into a neuron or glial cell.
51948	negative regulation of glutamate uptake involved in transmission of nerve impulse	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of L-glutamate into a neuron or glial cell.
51949	negative regulation of gamma-aminobutyric acid uptake involved in transmission of nerve impulse	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of gamma-aminobutyric acid (GABA, 4-aminobutyrate) into a neuron or glial cell.
51950	positive regulation of gamma-aminobutyric acid uptake involved in transmission of nerve impulse	P	Any process that activates, maintains or increases the frequency, rate or extent of the directed movement of gamma-aminobutyric acid (GABA, 4-aminobutyrate) into a neuron or glial cell.
51951	positive regulation of glutamate uptake involved in transmission of nerve impulse	P	Any process that activates, maintains or increases the frequency, rate or extent of the directed movement of L-glutamate into a neuron or glial cell.
51952	regulation of amine transport	P	Any process that modulates the frequency, rate or extent of the directed movement of amines into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
51953	negative regulation of amine transport	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of amines into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
51954	positive regulation of amine transport	P	Any process that activates, maintains or increases the frequency, rate or extent of the directed movement of amines into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
51955	regulation of amino acid transport	P	Any process that modulates the frequency, rate or extent of the directed movement of amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
51956	negative regulation of amino acid transport	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
51957	positive regulation of amino acid transport	P	Any process that activates, maintains or increases the frequency, rate or extent of the directed movement of amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
51958	methotrexate transport	P	The directed movement of methotrexate, 4-amino-10-methylformic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Methotrexate is a folic acid analogue and a potent competitive inhibitor of dihydrofolate reductase.
51959	dynein light intermediate chain binding	F	Interacting selectively and non-covalently with a light intermediate chain of the dynein complex.
51960	regulation of nervous system development	P	Any process that modulates the frequency, rate or extent of nervous system development, the origin and formation of nervous tissue.
51961	negative regulation of nervous system development	P	Any process that stops, prevents, or reduces the frequency, rate or extent of nervous system development, the origin and formation of nervous tissue.
51962	positive regulation of nervous system development	P	Any process that activates, maintains or increases the frequency, rate or extent of nervous system development, the origin and formation of nervous tissue.
51963	regulation of synapse assembly	P	Any process that modulates the frequency, rate or extent of synapse assembly, the aggregation, arrangement and bonding together of a set of components to form a synapse.
51964	negative regulation of synapse assembly	P	Any process that stops, prevents, or reduces the frequency, rate or extent of synapse assembly, the aggregation, arrangement and bonding together of a set of components to form a synapse.
51965	positive regulation of synapse assembly	P	Any process that activates, maintains or increases the frequency, rate or extent of synapse assembly, the aggregation, arrangement and bonding together of a set of components to form a synapse.
51966	regulation of synaptic transmission, glutamatergic	P	Any process that modulates the frequency, rate or extent of glutamatergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glutamate.
51967	negative regulation of synaptic transmission, glutamatergic	P	Any process that stops, prevents, or reduces the frequency, rate or extent of glutamatergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glutamate.
51968	positive regulation of synaptic transmission, glutamatergic	P	Any process that activates, maintains or increases the frequency, rate or extent of glutamatergic synaptic transmission, the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glutamate.
51969	regulation of transmission of nerve impulse	P	Any process that modulates the frequency, rate or extent of transmission of a nerve impulse, the sequential electrochemical polarization and depolarization that travels across the membrane of a neuron in response to stimulation.
51970	negative regulation of transmission of nerve impulse	P	Any process that stops, prevents, or reduces the frequency, rate or extent of transmission of a nerve impulse, the sequential electrochemical polarization and depolarization that travels across the membrane of a neuron in response to stimulation.
51971	positive regulation of transmission of nerve impulse	P	Any process that activates, maintains or increases the frequency, rate or extent of transmission of a nerve impulse, the sequential electrochemical polarization and depolarization that travels across the membrane of a neuron in response to stimulation.
51972	regulation of telomerase activity	P	Any process that modulates the frequency, rate or extent of telomerase activity, the catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). Telomerases catalyze extension of the 3'- end of a DNA strand by one deoxynucleotide at a time using an internal RNA template that encodes the telomeric repeat sequence.
51973	positive regulation of telomerase activity	P	Any process that activates or increases the frequency, rate or extent of telomerase activity, the catalysis of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).
51974	negative regulation of telomerase activity	P	Any process that stops or reduces the activity of the enzyme telomerase, which catalyzes of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).
51975	lysine biosynthetic process via alpha-aminoadipate and saccharopine	P	The chemical reactions and pathways resulting in the formation of lysine via the intermediates alpha-aminoadipic acid and saccharopine. This pathway is used by yeast and fungi to synthesize the essential amino acid L-lysine, and pathway intermediates are often incorporated into secondary metabolic processes. The pathway proceeds as follows: alpha-ketoglutarate is converted to homocitrate, which is metabolized to 3-carboxyhex-2-enedioate and then homoisocitrate. This is then decarboxylated to form alpha-ketoadipate, which is then converted to alpha-aminoadipate. This is then reduced to form alpha-aminoadipate 6-semialdehyde, which is metabolized to saccharopine and finally L-lysine.
51976	lysine biosynthetic process via alpha-aminoadipate and N2-acetyl-alpha-aminoadipate	P	The chemical reactions and pathways resulting in the formation of lysine via the intermediates alpha-aminoadipic acid and N2-acetyl-alpha-aminoadipate. This pathway of prokaryotic lysine biosynthesis via alpha-aminoadipate was discovered in the hyper-thermophilic Gram-negative eubacterium Thermus thermophilus. The pathway proceeds as follows: alpha-ketoglutarate is converted to homocitrate, which is metabolized to 3-carboxyhex-2-enedioate and then homoisocitrate. This is then decarboxylated to form alpha-ketoadipate, which is then converted to alpha-aminoadipate. This undergoes acetylation, to form N2-acetyl-alpha-aminoadipate, and is then phosphorylated to give N2-acetyl-alpha-aminoadipyl-delta-phosphate. This is converted to N2-acetyl-alpha-aminoadipate semialdehyde, which is then converted to N2-acetyl-L-lysine. A final deacetylation reaction produces L-lysine.
51977	lysophospholipid transport	P	The directed movement of phospholipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A lysophospholipid is a phospholipid that lacks one of its fatty acyl chains; it is an intermediate formed during digestion of dietary and biliary phospholipids.
51978	lysophospholipid transporter activity	F	Enables the directed movement of lysophospholipids into, out of or within a cell, or between cells. A lysophospholipid is a phospholipid that lacks one of its fatty acyl chains; it is an intermediate formed during digestion of dietary and biliary phospholipids.
51979	alginic acid acetylation	P	The addition of O-acetyl ester groups to alginic acid, a linear polymer of D-mannuronate and L-guluronate.
51980	iron-nicotianamine transmembrane transporter activity	F	Catalysis of the transfer of the iron chelate iron-nicotianamine (Fe-NA) from one side of a membrane to the other.
51981	copper chelate transmembrane transporter activity	F	Catalysis of the transfer of a copper chelate from one side of a membrane to the other. A copper chelate is a heterocyclic compound having a metal ion attached by coordinate bonds to at least two nonmetal ions.
51982	copper-nicotianamine transmembrane transporter activity	F	Catalysis of the transfer of the copper chelate copper-nicotianamine (Cu-NA) from one side of a membrane to the other.
51983	regulation of chromosome segregation	P	Any process that modulates the frequency, rate or extent of chromosome segregation, the process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets.
51984	positive regulation of chromosome segregation	P	Any process that activates or increases the frequency, rate or extent of chromosome segregation, the process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets.
51985	negative regulation of chromosome segregation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of chromosome segregation, the process in which genetic material, in the form of chromosomes, is organized and then physically separated and apportioned to two or more sets.
51986	negative regulation of attachment of spindle microtubules to kinetochore	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the attachment of spindle microtubules to the kinetochore.
51987	positive regulation of attachment of spindle microtubules to kinetochore	P	Any process that activates or increases the frequency, rate or extent of the attachment of spindle microtubules to the kinetochore.
51988	regulation of attachment of spindle microtubules to kinetochore	P	Any process that modulates the frequency, rate or extent of the attachment of spindle microtubules to the kinetochore.
51989	coproporphyrinogen dehydrogenase activity	F	Catalysis of the reaction: coproporphyrinogen III + 2 S-adenosyl-L-methionine = protoporphyrinogen IX + 2 CO2 + 2 L-methionine + 2 5'-deoxyadenosine.
51990	(R)-2-hydroxyglutarate dehydrogenase activity	F	Catalysis of the reaction: (R)-2-hydroxyglutarate + acceptor = 2-oxoglutarate + reduced acceptor.
51991	UDP-N-acetyl-D-glucosamine:N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine-diphosphoundecaprenol 4-beta-N-acetylglucosaminlytransferase activity	F	Catalysis of the reaction: N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine-diphosphoundecaprenol + UDP-N-acetyl-D-glucosamine = N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine-diphosphoundecaprenyl-N-acetylglucosamine + UDP.
51992	UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine:undecaprenyl-phosphate transferase activity	F	Catalysis of the reaction: UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine + di-trans,poly-cis-undecaprenyl phosphate = UMP + N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine-diphosphoundecaprenol.
51993	abscisic acid glucose ester beta-glucosidase activity	F	Catalysis of the reaction: abscisic acid glucose ester + H2O = abscisic acid + beta-D-glucose.
51994	P-methyltransferase activity	F	Catalysis of the transfer of a methyl group to the phosphorus atom of an acceptor molecule.
51995	Se-methyltransferase activity	F	Catalysis of the transfer of a methyl group to the selenium atom of an acceptor molecule.
51996	squalene synthase activity	F	Catalysis of the reaction: presqualene diphosphate + NADPH = squalene + NADP+ + diphosphate.
51997	2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase activity	F	Catalysis of the reaction: 5-hydroxy-2-oxo-4-ureido-2,5-dihydro-1H imidazole-5-carboxylate + H+ = S-allantoin + CO2.
51998	protein carboxyl O-methyltransferase activity	F	Catalysis of the transfer of a methyl group to a carboxyl group on a protein.
51999	mannosyl-inositol phosphorylceramide biosynthetic process	P	The chemical reactions and pathways resulting in the formation of mannosyl-inositol phosphorylceramide, any lipid with a phosphodiester bridge between an inositol residue and the ceramide group which contains a phosphoryl (-P(O)=) groups and a mannose derivative.
52000	Type IV pili-dependent aggregation	P	The formation of bacterial aggregates in liquid culture dependent on the presence of Type IV pili.
52001	Type IV pili-dependent localized adherence to host	P	Attachment of bacterial clusters to the surface of the host in a type IV pili dependent manner. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52002	metabolism by symbiont of substance in host	P	The chemical reactions and pathways performed by an organism in its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52003	negative regulation by symbiont of defense-related host salicylic acid-mediated signal transduction pathway	P	Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of host salicylic acid-mediated signal transduction pathways during the host defense response. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52004	negative regulation by symbiont of host salicylic acid-mediated defense response	P	Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of the salicylic acid-mediated defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52005	negative regulation by symbiont of host ethylene-mediated defense response	P	Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of the ethylene-mediated defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52006	catabolism by symbiont of substance in host	P	The chemical reactions and pathways performed by an organism in its host resulting in the breakdown of substances. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52007	biosynthesis by symbiont of substance in host	P	The chemical reactions and pathways performed by an organism in its host resulting in the formation of substances. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52008	disruption by symbiont of host cellular component	P	The chemical reactions and pathways performed by an organism resulting in the breakdown of cellular components of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52009	disruption by symbiont of host cell wall	P	A process carried out by a symbiont that breaks down the cell wall of its host. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52010	catabolism by symbiont of host cell wall cellulose	P	The chemical reactions and pathways performed by an organism resulting in the breakdown of cellulose in the host cell wall. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52011	catabolism by symbiont of host cell wall pectin	P	The chemical reactions and pathways performed by an organism resulting in the breakdown of pectin in the host cell wall. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52012	catabolism by symbiont of host cell wall chitin	P	The chemical reactions and pathways performed by an organism resulting in the breakdown of chitin in the host cell wall. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52013	catabolism by symbiont of host macromolecule	P	The chemical reactions and pathways performed by an organism resulting in the breakdown of macromolecules within the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52014	catabolism by symbiont of host protein	P	The chemical reactions and pathways performed by an organism resulting in the breakdown of protein macromolecules within the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52015	catabolism by symbiont of host carbohydrate	P	The chemical reactions and pathways performed by an organism resulting in the breakdown of carbohydrate molecules within the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52016	catabolism by symbiont of host glucan	P	The chemical reactions and pathways performed by an organism resulting in the breakdown of glucan molecules within the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52017	catabolism by symbiont of host xylan	P	The chemical reactions and pathways performed by an organism resulting in the breakdown of xylan within the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52018	modulation by symbiont of RNA levels in host	P	The alteration by an organism of the levels of RNA in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52019	modulation by symbiont of host hormone or growth regulator levels	P	The alteration by an organism of the levels of hormones or growth regulators in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52020	modification by symbiont of host cell wall	P	The process in which an organism effects a change in the structure or function of the host cell wall. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52021	modulation by symbiont of ethylene levels in host	P	The alteration by an organism of the levels of ethylene in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52022	modulation by symbiont of jasmonic acid levels in host	P	The alteration by an organism of the levels of jasmonic acid in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52023	modulation by symbiont of salicylic acid levels in host	P	The alteration by an organism of the levels of salicylic acid in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52024	positive regulation by symbiont of hormone or growth regulator levels in host	P	The increase by an organism of the levels of hormones or growth regulators in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52025	modification by symbiont of host cell membrane	P	The process in which an organism effects a change in the structure or function of a host cellular membrane. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52026	modulation by symbiont of host transcription	P	Any process in which an organism modulates the frequency, rate or extent of its host's transcription. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52027	modulation by symbiont of host signal transduction pathway	P	Any process in which an organism modulates the frequency, rate or extent of the host signal transduction pathways, the cascade of processes by which a signal interacts with a receptor. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52028	positive regulation by symbiont of host signal transduction pathway	P	Any process in which an organism activates, maintains or increases the frequency, rate or extent of the host signal transduction pathways, the cascade of processes by which a signal interacts with a receptor. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52029	negative regulation by symbiont of host signal transduction pathway	P	Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of the host signal transduction pathways, the cascade of processes by which a signal interacts with a receptor. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52031	modulation by symbiont of host defense response	P	Any process in which an organism modulates the frequency, rate or extent of the defense response of its host, the response mounted by the host in response to the presence of the organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52032	modulation by symbiont of host inflammatory response	P	Any process in which an organism modulates the frequency, rate or extent of the inflammatory response of the host organism; the inflammatory response is the immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52033	pathogen-associated molecular pattern dependent induction by symbiont of host innate immune response	P	Any process that involves recognition of a pathogen-associated molecular pattern, and by which an organism activates, maintains or increases the frequency, rate or extent of the innate immune response of the host organism; the innate immune response is the host's first line of defense against infection. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52034	negative regulation by symbiont of microbe-associated molecular pattern-induced host innate immune response	P	Any process that involves recognition of a microbe-associated molecular pattern, and by which an organism tops, prevents, or reduces the frequency, rate or extent of the innate immune response of the host organism; the innate immune response is the host's first line of defense against infection. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52035	positive regulation by symbiont of host inflammatory response	P	Any process in which an organism activates, maintains or increases the frequency, rate or extent of the inflammatory response of the host organism; the inflammatory response is the immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52036	negative regulation by symbiont of host inflammatory response	P	Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of the inflammatory response of the host organism; the inflammatory response is the immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52037	negative regulation by symbiont of host defense response	P	Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of the defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52038	modulation by symbiont of host intracellular transport	P	Any process in which an organism modulates the frequency, rate or extent of the directed movement of substances within the cell or cells of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52039	modification by symbiont of host cytoskeleton	P	The process in which an organism effects a change in the structure or function of the host cytoskeleton. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52040	modulation by symbiont of host programmed cell death	P	Any process in which an organism modulates the frequency, rate or extent of programmed cell death in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52041	negative regulation by symbiont of host programmed cell death	P	Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of programmed cell death in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52042	positive regulation by symbiont of host programmed cell death	P	Any process in which an organism activates, maintains or increases the frequency, rate or extent of programmed cell death in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52043	modification by symbiont of host cellular component	P	The process in which an organism effects a change in the structure or function of a host cellular component. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52046	modification by symbiont of host morphology or physiology via secreted substance	P	The process in which an organism effects a change in the structure or function of its host organism, mediated by a substance secreted by one of the organisms. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52047	interaction with other organism via secreted substance involved in symbiotic interaction	P	An interaction with a second organism mediated by a substance secreted by the first organism, where the two organisms are in a symbiotic interaction.
52048	interaction with host via secreted substance involved in symbiotic interaction	P	An interaction with the host organism mediated by a substance secreted by the other (symbiont) organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52049	interaction with host via protein secreted by type III secretion system	P	An interaction with the host organism mediated by a substance secreted by the symbiont organism by a type III secretion system. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52050	interaction with host via substance secreted by type IV secretion system	P	An interaction with the host organism mediated by a substance secreted by the other organism by a type IV secretion system. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52051	interaction with host via protein secreted by type II secretion system	P	An interaction with the host organism mediated by a substance secreted by the other organism by a type II secretion system. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52052	modification by symbiont of host morphology or physiology via protein secreted by type II secretion system	P	The process in which an organism effects a change in the structure or function of its host organism, mediated by a substance secreted by a type II secretion system in the organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52053	negative regulation by symbiont of host catalytic activity	P	Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of host enzyme activity. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52054	negative regulation by symbiont of host peptidase activity	P	Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of host protease activity, the catalysis of the hydrolysis of peptide bonds in a protein. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52055	modulation by symbiont of host molecular function	P	The process in which an organism effects a change in the function of a host protein via a direct interaction. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52056	negative regulation by symbiont of host molecular function	P	Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of the functional activity of host proteins. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52057	modification by symbiont of host morphology or physiology via protein secreted by type III secretion system	P	The process in which an organism effects a change in the structure or function of its host organism, mediated by a substance secreted by a type III secretion system in the organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52058	modification by symbiont of host morphology or physiology via substance secreted by type IV secretion system	P	The process in which an organism effects a change in the structure or function of its host organism, mediated by a substance secreted by a type IV secretion system in the organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52059	evasion or tolerance by symbiont of host-produced reactive oxygen species	P	The process in which an organism avoids the effects of reactive oxygen species produced as a defense response by the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52060	evasion or tolerance by symbiont of host-produced nitric oxide	P	The process in which an organism avoids the effects of nitric oxide produced as a defense response by the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52061	evasion or tolerance by symbiont of host-produced phytoalexins	P	The process in which an organism avoids the effects of phytoalexins produced as a defense response by the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52062	induction by symbiont of host phytoalexin production	P	The activation by an organism of the production of phytoalexins as part of the defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52063	induction by symbiont of defense-related host nitric oxide production	P	The activation by an organism of the production of nitric oxide as part of the defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52064	induction by symbiont of defense-related host reactive oxygen species production	P	The activation by an organism of the production of reactive oxygen species as part of the defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52065	positive regulation by organism of defense-related calcium ion flux in other organism involved in symbiotic interaction	P	Any process in which an organism activates, maintains or increases the frequency, rate or extent of fluxes of calcium ions that occur as part of the defense response of a second organism, where the two organisms are in a symbiotic interaction.
52066	entry of symbiont into host cell by promotion of host phagocytosis	P	The invasion by an organism of a cell of its host organism by utilizing the host phagocytosis mechanism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52067	negative regulation by symbiont of entry into host cell via phagocytosis	P	Any process in which an organism stops or prevents itself undergoing phagocytosis into a cell in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52068	negative regulation by symbiont of host jasmonic acid-mediated defense response	P	Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of the jasmonic acid-mediated defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52069	negative regulation by symbiont of defense-related host jasmonic acid-mediated signal transduction pathway	P	Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of host jasmonic acid-mediated signal transduction pathways during the host defense response. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52070	negative regulation by symbiont of defense-related host ethylene-mediated signal transduction pathway	P	Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of host ethylene-mediated signal transduction pathways during the host defense response. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52071	positive regulation by symbiont of defense-related host ethylene-mediated signal transduction pathway	P	Any process in which an organism activates, maintains or increases the frequency, rate or extent of host ethylene-mediated signal transduction pathways during the host defense response. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52072	positive regulation by symbiont of defense-related host salicylic acid-mediated signal transduction pathway	P	Any process in which an organism activates, maintains or increases the frequency, rate or extent of host salicylic acid-mediated signal transduction pathways during the host defense response. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52073	positive regulation by symbiont of defense-related host jasmonic acid-mediated signal transduction pathway	P	Any process in which an organism activates, maintains or increases the frequency, rate or extent of host jasmonic acid-mediated signal transduction pathways during the host defense response. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52074	positive regulation by symbiont of host salicylic acid-mediated defense response	P	Any process in which an organism activates, maintains or increases the frequency, rate or extent of the salicylic acid-mediated defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52075	positive regulation by symbiont of host jasmonic acid-mediated defense response	P	Any process in which an organism activates, maintains or increases the frequency, rate or extent of the jasmonic acid-mediated defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52076	positive regulation by symbiont of host ethylene-mediated defense response	P	Any process in which an organism activates, maintains or increases the frequency, rate or extent of the ethylene-mediated defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52077	modulation by symbiont of defense-related host ethylene-mediated signal transduction pathway	P	Any process in which an organism modulates the frequency, rate or extent of host ethylene-mediated signal transduction pathways during the host defense response. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52078	negative regulation by symbiont of defense-related host MAP kinase-mediated signal transduction pathway	P	Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of host MAP kinase-mediated signal transduction pathways during the host defense response. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52079	positive regulation by symbiont of defense-related host MAP kinase-mediated signal transduction pathway	P	Any process in which an organism activates, maintains or increases the frequency, rate or extent of host MAP kinase-mediated signal transduction pathways during the host defense response. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52080	modulation by symbiont of defense-related host MAP kinase-mediated signal transduction pathway	P	Any process in which an organism modulates the frequency, rate or extent of host MAP kinase-mediated signal transduction pathways during the host defense response. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52081	modulation by symbiont of defense-related host salicylic acid-mediated signal transduction pathway	P	Any process in which an organism modulates the frequency, rate or extent of host salicylic acid-mediated signal transduction pathways during the host defense response. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52082	modulation by symbiont of defense-related host jasmonic acid-mediated signal transduction pathway	P	Any process in which an organism modulates the frequency, rate or extent of host jasmonic acid-mediated signal transduction pathways during the host defense response. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52083	negative regulation by symbiont of host cell-mediated immune response	P	Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of the cell mediated immune response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52084	modulation by symbiont of host ethylene-mediated defense response	P	Any process in which an organism modulates the frequency, rate or extent of the ethylene-mediated defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52085	negative regulation by symbiont of host T-cell mediated immune response	P	Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of the T-cell mediated immune response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52086	negative regulation by symbiont of host B-cell mediated immune response	P	Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of the B-cell mediated immune response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52087	negative regulation by symbiont of defense-related host callose deposition	P	Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of callose deposition performed by the host as part of its defense response. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52088	modulation by symbiont of host jasmonic acid-mediated defense response	P	Any process in which an organism modulates the frequency, rate or extent of the jasmonic acid-mediated defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52089	modulation by symbiont of host salicylic acid-mediated defense response	P	Any process in which an organism modulates the frequency, rate or extent of the salicylic acid-mediated defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52090	modulation by symbiont of defense-related host callose deposition	P	Any process in which an organism modulates the frequency, rate or extent of callose deposition by the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52091	modulation by symbiont of nutrient release from host	P	Any process in which an organism modulates the frequency, rate or extent of the release of nutrients from its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52092	positive regulation by symbiont of nutrient release from host	P	Any process in which an organism activates, maintains or increases the frequency, rate or extent of the release of nutrients from its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52093	formation of specialized structure for nutrient acquisition from host	P	The assembly by an organism of a cellular component or anatomical structure for the purpose of obtaining nutrients from its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52094	formation by symbiont of haustorium for nutrient acquisition from host	P	The assembly by an organism of a haustorium, a projection from a cell or tissue that penetrates the host's tissues for the purpose of obtaining nutrients from its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52095	formation of specialized structure for nutrient acquisition from other organism involved in symbiotic interaction	P	The assembly by an organism of a cellular component or anatomical structure for the purpose of obtaining nutrients from a second organism, where the two organisms are in a symbiotic interaction.
52096	formation by symbiont of syncytium involving giant cell for nutrient acquisition from host	P	The assembly by an organism of a syncytium, a nematode-induced multi-nucleate and physiologically active aggregation of fused root cells which exclusively provides the nematode with nourishment during its sedentary life, for the purpose of obtaining nutrients from its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52097	interspecies quorum sensing	P	The process in which a community of single-celled organisms of different species monitors population density by detecting the concentration of small diffusible signal molecules.
52098	formation by host of specialized structure for nutrient acquisition from symbiont	P	The assembly by an organism of a cellular component or anatomical structure for the purpose of obtaining nutrients from a symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.
52099	acquisition by symbiont of nutrients from host via siderophores	P	The process that begins with the production and formation of siderophores in an organism that are required for the acquisition and utilization of nutrients from its host organism, and the ends with the acquirement of the nutrients. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52100	intraspecies quorum sensing	P	The process in which single-celled organisms of the same species monitor population density by detecting the concentration of small, diffusible signal molecules.
52101	induction by symbiont of host resistance gene-dependent defense response	P	The activation by an organism of the resistance gene-dependent defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52102	positive regulation by symbiont of defense-related host calcium-dependent protein kinase pathway	P	Any process in which an organism activates, maintains or increases the frequency, rate or extent of the host calcium-dependent protein kinase pathway during the host defense response. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52103	induction by symbiont of host induced systemic resistance	P	Any process in which an organism activates induced systemic resistance in the host; induced systemic resistance is a response that confers broad spectrum systemic resistance to disease and that does not depend upon salicylic acid signaling. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52104	induction by symbiont of host systemic acquired resistance	P	Any process in which an organism activates systemic acquired resistance in the host organism; systemic acquired resistance is a salicylic acid-mediated response that confers broad spectrum systemic resistance. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52105	induction by symbiont of defense-related host cell wall thickening	P	The activation by an organism of host processes resulting in the thickening of its cell walls, occurring as part of the defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52106	quorum sensing involved in interaction with host	P	The process in which a community of single-celled organisms living in intimate contact with a host organism monitors population density by detecting the concentration of small diffusible signal molecules. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52107	positive regulation by symbiont of defense-related host callose deposition	P	Any process in which an organism activates, maintains or increases the frequency, rate or extent of callose deposition by the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52109	positive regulation by symbiont of defense-related host cell wall callose deposition	P	Any process in which an organism activates, maintains or increases the frequency, rate or extent of the deposition of callose by the host in its cell walls, occurring as part of the defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52110	occlusion by symbiont of host vascular system	P	The process in which an organism reduces the flow of fluid within its host's vascular system, the vessels and tissue that carry or circulate fluids, such as blood, lymph or sap, through the body of an animal or plant. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52111	modification by symbiont of host structure	P	The process in which an organism effects a change in an anatomical part or cellular component of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52112	occlusion by symbiont of host xylem	P	The process in which an organism reduces the flow of fluid within the host xylem, the tissue in plants that carries water and nutrients up from the roots to the shoot and leaves. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52115	energy taxis in host environment	P	The directed movement of a motile cell or organism in the environment of its host organism in response to physical parameters involved in energy generation, such as light, oxygen, and oxidizable substrates. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52116	chemotaxis in host environment	P	The directed movement of a motile cell or organism in response to a specific chemical concentration gradient on, within or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52117	aerotaxis in host environment	P	The movement of a motile cell or organism in response to environmental oxygen on, within or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52118	positive energy taxis in host environment	P	The directed movement of a motile cell or organism on, within or near its host organism towards a higher level of a physical stimulus involved in energy generation, such as light, oxygen, and oxidizable substrates. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52119	negative energy taxis in host environment	P	The directed movement of a motile cell or organism on, within or near its host organism towards a lower level of a physical stimulus involved in energy generation, such as light, oxygen, and oxidizable substrates. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52120	positive aerotaxis in host environment	P	The directed movement of a motile cell or organism towards a higher concentration of environmental oxygen on, within or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52121	positive chemotaxis in host environment	P	The directed movement of a motile cell or organism towards a higher concentration of a chemical on, within or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52122	negative aerotaxis in host environment	P	The directed movement of a motile cell or organism towards a lower concentration of environmental oxygen on, within or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52123	negative chemotaxis in host environment	P	The directed movement of a motile cell or organism towards a lower concentration of a specific chemical on, within or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52124	energy taxis within host	P	The directed movement of a motile cell or organism within its host organism in response to physical parameters involved in energy generation, such as light, oxygen, and oxidizable substrates. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52125	energy taxis on or near host	P	The directed movement of a motile cell or organism on or near its host organism in response to physical parameters involved in energy generation, such as light, oxygen, and oxidizable substrates. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52126	movement in host environment	P	The directed movement of an organism or motile cell on, within or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52127	movement on or near host	P	The directed movement of an organism or motile cell on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52128	positive energy taxis	P	The directed movement of a motile cell or organism towards a higher level of a physical stimulus involved in energy generation, such as light, oxygen, and oxidizable substrates.
52129	negative energy taxis	P	The directed movement of a motile cell or organism towards a lower level of a physical stimulus involved in energy generation, such as light, oxygen, and oxidizable substrates.
52130	negative aerotaxis	P	The directed movement of a motile cell or organism towards a lower concentration of environmental oxygen.
52131	positive aerotaxis	P	The directed movement of a motile cell or organism towards a higher concentration of environmental oxygen.
52132	positive aerotaxis on or near host	P	The directed movement of a motile cell or organism towards a higher concentration of environmental oxygen on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52133	positive aerotaxis in host	P	The directed movement of a motile cell or organism towards a higher concentration of environmental oxygen within its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52134	negative aerotaxis on or near host	P	The directed movement of a motile cell or organism towards a lower concentration of environmental oxygen on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52135	negative aerotaxis in host	P	The directed movement of a motile cell or organism towards a lower concentration of environmental oxygen within its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52136	negative chemotaxis on or near host	P	The directed movement of a motile cell or organism towards a lower concentration of a specific chemical on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52137	aerotaxis in host	P	The movement of a motile cell or organism in response to environmental oxygen within its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52138	aerotaxis on or near host	P	The movement of a motile cell or organism in response to environmental oxygen on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52139	negative chemotaxis in host	P	The directed movement of a motile cell or organism towards a lower concentration of a specific chemical within its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52140	positive chemotaxis in host	P	The directed movement of a motile cell or organism towards a higher concentration of a specific chemical within its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52141	positive chemotaxis on or near host	P	The directed movement of a motile cell or organism towards a higher concentration of a specific chemical on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52142	chemotaxis within host	P	The directed movement of a motile cell or organism in response to a specific chemical concentration gradient within its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52143	chemotaxis on or near host involved in symbiotic interaction	P	The directed movement of a motile cell or organism in response to a specific chemical concentration gradient on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52144	negative energy taxis in host	P	The directed movement of a motile cell or organism within its host organism towards a lower level of a physical stimulus involved in energy generation, such as light, oxygen, and oxidizable substrates. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52145	negative energy taxis on or near host	P	The directed movement of a motile cell or organism on or near its host organism towards a lower level of a physical stimulus involved in energy generation, such as light, oxygen, and oxidizable substrates. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52146	positive energy taxis on or near host	P	The directed movement of a motile cell or organism on or near its host organism towards a higher level of a physical stimulus involved in energy generation, such as light, oxygen, and oxidizable substrates. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52147	positive energy taxis in host	P	The directed movement of a motile cell or organism within its host organism towards a higher level of a physical stimulus involved in energy generation, such as light, oxygen, and oxidizable substrates. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52148	modulation by symbiont of host catalytic activity	P	The process in which an organism effects a change in host enzyme activity. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52149	modulation by symbiont of host peptidase activity	P	The process in which an organism effects a change in host peptidase activity, the catalysis of the hydrolysis of peptide bonds in a protein. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52150	modulation by symbiont of host apoptotic process	P	Any process in which an organism modulates the frequency, rate or extent of programmed cell death in the host, where programmed cell death proceeds by apoptosis. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52151	positive regulation by symbiont of host apoptotic process	P	Any process in which an organism activates, maintains or increases the frequency, rate or extent of programmed cell death in the host, where programmed cell death proceeds by apoptosis. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52154	modulation by symbiont of host B-cell mediated immune response	P	Any process in which an organism modulates the frequency, rate or extent of the B-cell mediated immune response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52155	modulation by symbiont of host cell-mediated immune response	P	Any process in which an organism modulates the frequency, rate or extent of any form of cell-based immune response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52156	modulation by symbiont of host T-cell mediated immune response	P	Any process in which an organism modulates the frequency, rate or extent of the T-cell mediated immune response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52157	modulation by symbiont of microbe-associated molecular pattern-induced host innate immune response	P	Any process that involves recognition of a microbe-associated molecular pattern, and by which an organism modulates the frequency, rate or extent of the innate immune response of the host organism; the innate immune response is the host's first line of defense against infection. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52158	modulation by symbiont of host resistance gene-dependent defense response	P	Any process in which an organism modulates the frequency, rate or extent of the resistance gene-dependent defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52159	modulation by symbiont of host induced systemic resistance	P	Any process in which an organism modulates the frequency, rate or extent of induced systemic resistance in the host organism; induced systemic resistance is a response that confers broad spectrum systemic resistance to disease and that does not depend upon salicylic acid signaling. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52160	modulation by symbiont of host systemic acquired resistance	P	Any process in which an organism modulates the frequency, rate or extent of systemic acquired resistance in the host organism; systemic acquired resistance is a salicylic acid-mediated response that confers broad spectrum systemic resistance. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52161	modulation by symbiont of defense-related host cell wall thickening	P	Any process in which an organism modulates the frequency, rate or extent of host processes resulting in the thickening of its cell walls, occurring as part of the defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52162	modulation by symbiont of defense-related host calcium ion flux	P	Any process in which an organism modulates the frequency, rate or extent of calcium ion fluxes as part of the defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52163	modulation by symbiont of defense-related host nitric oxide production	P	Any process in which an organism modulates the frequency, rate or extent of the production of nitric oxide as part of the defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52164	modulation by symbiont of defense-related host reactive oxygen species production	P	Any process in which an organism modulates the frequency, rate or extent of the production of reactive oxygen species as part of the defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52165	modulation by symbiont of host phytoalexin production	P	Any process in which an organism modulates the frequency, rate or extent of production of phytoalexins as part of the defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52166	positive regulation by symbiont of host innate immune response	P	Any process in which an organism activates, maintains or increases the frequency, rate or extent of the innate immune response of the host organism; the innate immune response is the host's first line of defense against infection. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52167	modulation by symbiont of host innate immune response	P	Any process in which an organism modulates the frequency, rate or extent of the innate immune response of the host organism; the innate immune response is the host's first line of defense against infection. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52168	modulation by symbiont of defense-related host calcium-dependent protein kinase pathway	P	Any process in which an organism modulates the frequency, rate or extent of the host calcium-dependent protein kinase signal transduction pathways during the host defense response. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52169	pathogen-associated molecular pattern dependent modulation by symbiont of host innate immune response	P	Any process that involves recognition of a pathogen-associated molecular pattern, and by which an organism modulates the frequency, rate or extent of the innate immune response of the host organism; the innate immune response is the host's first line of defense against infection. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52170	negative regulation by symbiont of host innate immune response	P	Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of the innate immune response of the host organism, the host's first line of defense against infection. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52172	metabolism by symbiont of host cell wall cellulose	P	The chemical reactions and pathways performed by an organism involving cellulose in the cell wall of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52173	response to defenses of other organism involved in symbiotic interaction	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detecting the defenses of a second organism, where the two organisms are in a symbiotic interaction.
52174	metabolism by symbiont of host macromolecule	P	The chemical reactions and pathways performed by an organism involving macromolecules within the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52175	metabolism by symbiont of host carbohydrate	P	The chemical reactions and pathways performed by an organism involving carbohydrates within the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52176	metabolism by symbiont of host glucan	P	The chemical reactions and pathways performed by an organism involving glucans within the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52177	metabolism by symbiont of host xylan	P	The chemical reactions and pathways performed by an organism involving xylan within the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52178	metabolism by symbiont of host cell wall chitin	P	The chemical reactions and pathways performed by an organism involving chitin in the cell wall of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52179	metabolism by symbiont of host cell wall pectin	P	The chemical reactions and pathways performed by an organism involving pectin in the cell wall of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52180	negative regulation of peptidase activity in other organism involved in symbiotic interaction	P	Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of protease activity, the catalysis of the hydrolysis of peptide bonds in a protein, in a second organism, where the two organisms are in a symbiotic interaction.
52181	modulation by host of symbiont defense response	P	Any process in which an organism activates, maintains or increases the frequency, rate or extent of the resistance gene-dependent defense response of the symbiont. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.
52182	modification by host of symbiont morphology or physiology via secreted substance	P	The process in which an organism effects a change in the structure or function of a symbiont organism, mediated by a substance secreted by one of the organisms. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.
52183	modification by host of symbiont structure	P	The process in which an organism effects a change in an anatomical part or cellular component of the host organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.
52185	modification of structure of other organism involved in symbiotic interaction	P	The process in which an organism effects a change in an anatomical part or cellular component of a second organism, where the two organisms are in a symbiotic interaction.
52186	modulation by organism of hormone or growth regulator levels in other organism involved in symbiotic interaction	P	The alteration by an organism of the levels of hormones or growth regulators in a second organism, where the two organisms are in a symbiotic interaction.
52187	modification by host of symbiont cellular component	P	The process in which an organism effects a change in the structure or function of a symbiont cellular component. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.
52188	modification of cellular component in other organism involved in symbiotic interaction	P	The process in which an organism effects a change in the structure or function of a cellular component in a second organism, where the two organisms are in a symbiotic interaction.
52189	modulation by symbiont of defense-related host cell wall callose deposition	P	Any process in which an organism modulates the frequency, rate or extent of the deposition of callose by the host in its cell walls, occurring as part of the defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52190	modulation by symbiont of host phagocytosis	P	Any process in which an organism modulates the frequency, rate or extent of phagocytosis, the engulfing by phagocytes of external particulate material, in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52191	positive regulation by symbiont of host phagocytosis	P	Any process in which an organism activates, maintains or increases the frequency, rate or extent of phagocytosis, the engulfing by phagocytes of external particulate material, in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52192	movement in environment of other organism involved in symbiotic interaction	P	The directed movement of an organism or motile cell on, within or near a second organism, where the two organisms are in a symbiotic interaction.
52195	movement on or near other organism involved in symbiotic interaction	P	The directed movement of an organism or motile cell on or near a second organism, where the two organisms are in a symbiotic interaction.
52196	negative regulation by host of symbiont defense response	P	Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of the defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.
52197	positive regulation by host of symbiont defense response	P	Any process in which an organism activates, maintains or increases the frequency, rate or extent of the defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.
52198	modulation of peptidase activity in other organism involved in symbiotic interaction	P	The process in which an organism effects a change in peptidase activity, the catalysis of the hydrolysis of peptide bonds in a protein, in a second organism, where the two organisms are in a symbiotic interaction.
52199	negative regulation of catalytic activity in other organism involved in symbiotic interaction	P	Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of enzyme activity in a second organism, where the two organisms are in a symbiotic interaction.
52200	response to host defenses	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detecting the defenses of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52201	response to symbiont defenses	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detecting the defenses of a symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.
52202	negative regulation by symbiont of defense-related host cell wall callose deposition	P	Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of the deposition of callose by the host in its cell walls, occurring as part of the defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52203	modulation of catalytic activity in other organism involved in symbiotic interaction	P	The process in which an organism effects a change in enzyme activity in a second organism, where the two organisms are in a symbiotic interaction.
52204	negative regulation of molecular function in other organism involved in symbiotic interaction	P	Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of the functional activity of proteins in a second organism, where the two organisms are in a symbiotic interaction.
52205	modulation of molecular function in other organism involved in symbiotic interaction	P	The process in which an organism effects a change in the function of proteins in a second organism, where the two organisms are in a symbiotic interaction.
52206	modification of morphology or physiology of other organism via protein secreted by type II secretion system involved in symbiotic interaction	P	The process in which an organism effects a change in the structure or function of a second organism, mediated by a substance secreted by a type II secretion system in the first organism, where the two organisms are in a symbiotic interaction.
52207	modification of morphology or physiology of other organism via protein secreted by type III secretion system involved in symbiotic interaction	P	The process in which an organism effects a change in the structure or function of a second organism, mediated by a substance secreted by a type III secretion system in the first organism, where the two organisms are in a symbiotic interaction.
52208	modification of morphology or physiology of other organism via substance secreted by type IV secretion system involved in symbiotic interaction	P	The process in which an organism effects a change in the structure or function of a second organism, mediated by a substance secreted by a type IV secretion system in the first organism, where the two organisms are in a symbiotic interaction.
52209	interaction with other organism via substance secreted by type IV secretion system involved in symbiotic interaction	P	An interaction with a second organism mediated by a substance secreted by the first organism by a type IV secretion system, where the two organisms are in a symbiotic interaction.
52210	interaction with other organism via protein secreted by type III secretion system involved in symbiotic interaction	P	An interaction with a second organism mediated by a substance secreted by the first organism by a type III secretion system, where the two organisms are in a symbiotic interaction.
52211	interaction with other organism via protein secreted by type II secretion system involved in symbiotic interaction	P	An interaction with a second organism mediated by a substance secreted by the first organism by a type II secretion system, where the two organisms are in a symbiotic interaction.
52212	modification of morphology or physiology of other organism via secreted substance involved in symbiotic interaction	P	The process in which an organism effects a change in the structure or function of a second organism, mediated by a substance secreted by one of the organisms, where the two organisms are in a symbiotic interaction.
52213	interaction with symbiont via secreted substance involved in symbiotic interaction	P	An interaction with the symbiont organism mediated by a substance secreted by the other (host) organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.
52214	metabolism of substance in other organism involved in symbiotic interaction	P	The chemical reactions and pathways performed by an organism in a second organism, where the two organisms are in a symbiotic interaction.
52215	energy taxis in environment of other organism involved in symbiotic interaction	P	The directed movement of a motile cell or organism in the environment of a second organism in response to physical parameters involved in energy generation, such as light, oxygen, and oxidizable substrates, where the two organisms are in a symbiotic interaction.
52216	chemotaxis in environment of other organism involved in symbiotic interaction	P	The directed movement of a motile cell or organism in response to a specific chemical concentration gradient on, within or near a second organism, where the two organisms are in a symbiotic interaction.
52217	aerotaxis in environment of other organism involved in symbiotic interaction	P	The movement of a motile cell or organism in response to environmental oxygen on, within or near a second organism, where the two organisms are in a symbiotic interaction.
52218	positive energy taxis in environment of other organism involved in symbiotic interaction	P	The directed movement of a motile cell or organism on, within or near a second organism towards a higher level of a physical stimulus involved in energy generation, such as light, oxygen, and oxidizable substrates, where the two organisms are in a symbiotic interaction.
52219	negative energy taxis in environment of other organism involved in symbiotic interaction	P	The directed movement of a motile cell or organism on, within or near a second organism towards a lower level of a physical stimulus involved in energy generation, such as light, oxygen, and oxidizable substrates, where the two organisms are in a symbiotic interaction.
52220	positive aerotaxis in environment of other organism involved in symbiotic interaction	P	The directed movement of a motile cell or organism towards a higher concentration of environmental oxygen on, within or near a second organism, where the two organisms are in a symbiotic interaction.
52221	positive chemotaxis in environment of other organism involved in symbiotic interaction	P	The directed movement of a motile cell or organism towards a higher concentration of a chemical on, within or near a second organism, where the two organisms are in a symbiotic interaction.
52222	negative aerotaxis in environment of other organism involved in symbiotic interaction	P	The directed movement of a motile cell or organism towards a lower concentration of environmental oxygen on, within or near a second organism, where the two organisms are in a symbiotic interaction.
52223	negative chemotaxis in environment of other organism involved in symbiotic interaction	P	The directed movement of a motile cell or organism towards a lower concentration of a specific chemical on, within or near a second organism, where the two organisms are in a symbiotic interaction.
52224	energy taxis in other organism involved in symbiotic interaction	P	The directed movement of a motile cell or organism within a second organism in response to physical parameters involved in energy generation, such as light, oxygen, and oxidizable substrates, where the two organisms are in a symbiotic interaction.
52225	energy taxis on or near other organism involved in symbiotic interaction	P	The directed movement of a motile cell or organism on or near a second organism in response to physical parameters involved in energy generation, such as light, oxygen, and oxidizable substrates, where the two organisms are in a symbiotic interaction.
52226	biosynthesis of substance in other organism involved in symbiotic interaction	P	The chemical reactions and pathways performed by an organism in a second organism resulting in the formation of substances, where the two organisms are in a symbiotic interaction.
52227	catabolism of substance in other organism involved in symbiotic interaction	P	The chemical reactions and pathways performed by an organism in a second organism resulting in the breakdown of substances, where the two organisms are in a symbiotic interaction.
52228	metabolism by symbiont of host protein	P	The chemical reactions and pathways performed by an organism involving protein macromolecules within the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52229	metabolism of macromolecule in other organism involved in symbiotic interaction	P	The chemical reactions and pathways performed by an organism involving macromolecules within a second organism, where the two organisms are in a symbiotic interaction.
52230	modulation of intracellular transport in other organism involved in symbiotic interaction	P	Any process in which an organism modulates the frequency, rate or extent of the directed movement of substances within the cell or cells of a second organism, where the two organisms are in a symbiotic interaction.
52231	modulation of phagocytosis in other organism involved in symbiotic interaction	P	Any process in which an organism modulates the frequency, rate or extent of phagocytosis, the engulfing by phagocytes of external particulate material, in a second organism, where the two organisms are in a symbiotic interaction.
52232	positive aerotaxis on or near other organism involved in symbiotic interaction	P	The directed movement of a motile cell or organism towards a higher concentration of environmental oxygen on or near a second organism, where the two organisms are in a symbiotic interaction.
52233	positive aerotaxis in other organism involved in symbiotic interaction	P	The directed movement of a motile cell or organism towards a higher concentration of environmental oxygen within a second organism, where the two organisms are in a symbiotic interaction.
52234	negative aerotaxis on or near other organism involved in symbiotic interaction	P	The directed movement of a motile cell or organism towards a lower concentration of environmental oxygen on or near a second organism, where the two organisms are in a symbiotic interaction.
52235	negative aerotaxis in other organism involved in symbiotic interaction	P	The directed movement of a motile cell or organism towards a lower concentration of environmental oxygen within a second organism, where the two organisms are in a symbiotic interaction.
52236	negative chemotaxis on or near other organism involved in symbiotic interaction	P	The directed movement of a motile cell or organism towards a lower concentration of a specific chemical on or near a second organism, where the two organisms are in a symbiotic interaction.
52237	aerotaxis in other organism involved in symbiotic interaction	P	The movement of a motile cell or organism in response to environmental oxygen within a second organism, where the two organisms are in a symbiotic interaction.
52238	aerotaxis on or near other organism involved in symbiotic interaction	P	The movement of a motile cell or organism in response to environmental oxygen on or near a second organism, where the two organisms are in a symbiotic interaction.
52239	negative chemotaxis in other organism involved in symbiotic interaction	P	The directed movement of a motile cell or organism towards a lower concentration of a specific chemical within a second organism, where the two organisms are in a symbiotic interaction.
52240	positive chemotaxis in other organism involved in symbiotic interaction	P	The directed movement of a motile cell or organism towards a higher concentration of a specific chemical within a second organism, where the two organisms are in a symbiotic interaction.
52241	positive chemotaxis on or near other organism involved in symbiotic interaction	P	The directed movement of a motile cell or organism towards a higher concentration of a specific chemical on or near a second organism, where the two organisms are in a symbiotic interaction.
52242	chemotaxis in other organism involved in symbiotic interaction	P	The directed movement of a motile cell or organism in response to a specific chemical concentration gradient within a second organism, where the two organisms are in a symbiotic interaction.
52243	chemotaxis on or near other organism involved in symbiotic interaction	P	The directed movement of a motile cell or organism in response to a specific chemical concentration gradient on or near a second organism, where the two organisms are in a symbiotic interaction.
52244	negative energy taxis in other organism involved in symbiotic interaction	P	The directed movement of a motile cell or organism within a second organism towards a lower level of a physical stimulus involved in energy generation, such as light, oxygen, and oxidizable substrates, where the two organisms are in a symbiotic interaction.
52245	negative energy taxis on or near other organism involved in symbiotic interaction	P	The directed movement of a motile cell or organism on or near a second organism towards a lower level of a physical stimulus involved in energy generation, such as light, oxygen, and oxidizable substrates, where the two organisms are in a symbiotic interaction.
52246	positive energy taxis on or near other organism involved in symbiotic interaction	P	The directed movement of a motile cell or organism on or near a second organism towards a higher level of a physical stimulus involved in energy generation, such as light, oxygen, and oxidizable substrates, where the two organisms are in a symbiotic interaction.
52247	positive energy taxis in other organism involved in symbiotic interaction	P	The directed movement of a motile cell or organism within a second organism towards a higher level of a physical stimulus involved in energy generation, such as light, oxygen, and oxidizable substrates, where the two organisms are in a symbiotic interaction.
52248	modulation of programmed cell death in other organism involved in symbiotic interaction	P	Any process in which an organism modulates the frequency, rate or extent of programmed cell death in a second organism, where the two organisms are in a symbiotic interaction.
52249	modulation of RNA levels in other organism involved in symbiotic interaction	P	The alteration by an organism of the levels of RNA in a second organism, where the two organisms are in a symbiotic interaction.
52250	modulation of signal transduction in other organism involved in symbiotic interaction	P	Any process in which an organism modulates the frequency, rate or extent of the signal transduction pathways, the cascade of processes by which a signal interacts with a receptor, occurring in a second organism, where the two organisms are in a symbiotic interaction.
52251	induction by organism of defense response of other organism involved in symbiotic interaction	P	The activation by an organism of the defense response of a second organism, where the two organisms are in a symbiotic interaction.
52252	negative regulation by organism of defense-related salicylic acid-mediated signal transduction pathway of other organism involved in symbiotic interaction	P	Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of salicylic acid-mediated signal transduction pathways that occur as part of the defense response of a second organism, where the two organisms are in a symbiotic interaction.
52253	negative regulation by organism of salicylic acid-mediated defense response of other organism involved in symbiotic interaction	P	Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of the salicylic acid-mediated defense response of a second organism, where the two organisms are in a symbiotic interaction.
52254	negative regulation by organism of ethylene-mediated defense response of other organism involved in symbiotic interaction	P	Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of the ethylene-mediated defense response of a second organism, where the two organisms are in a symbiotic interaction.
52255	modulation by organism of defense response of other organism involved in symbiotic interaction	P	Any process in which an organism modulates the frequency, rate or extent of the defense response of a second organism, the response mounted by that organism in response to the presence of the first organism, where the two organisms are in a symbiotic interaction.
52256	modulation by organism of inflammatory response of other organism involved in symbiotic interaction	P	Any process in which an organism modulates the frequency, rate or extent of the inflammatory response, the immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents, of a second organism, where the two organisms are in a symbiotic interaction.
52257	pathogen-associated molecular pattern dependent induction by organism of innate immune response of other organism involved in symbiotic interaction	P	Any process that involves recognition of a pathogen-associated molecular pattern, and by which an organism activates, maintains or increases the frequency, rate or extent of the innate immune response of a second organism, where the two organisms are in a symbiotic interaction.
52258	negative regulation by organism of pathogen-associated molecular pattern-induced innate immune response of other organism involved in symbiotic interaction	P	Any process that involves recognition of a microbe-associated molecular pattern, and by which an organism stops, prevents, or reduces the frequency, rate or extent of the innate immune response, the first line of defense against infection, of a second organism, where the two organisms are in a symbiotic interaction.
52259	positive regulation by organism of inflammatory response of other organism involved in symbiotic interaction	P	Any process in which an organism activates, maintains or increases the frequency, rate or extent of the inflammatory response, the immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents, of a second organism, where the two organisms are in a symbiotic interaction.
52260	negative regulation by organism of inflammatory response of other organism involved in symbiotic interaction	P	Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of the inflammatory response; the inflammatory response is the immediate defensive reaction (by vertebrate tissue) to infection or injury caused by chemical or physical agents, of a second organism, where the two organisms are in a symbiotic interaction.
52261	suppression of defense response of other organism involved in symbiotic interaction	P	Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of the defense response of a second organism, where the two organisms are in a symbiotic interaction.
52262	induction by organism of phytoalexin production in other organism involved in symbiotic interaction	P	The activation by an organism of the production of phytoalexins that occurs as part of the defense response of a second organism, where the two organisms are in a symbiotic interaction.
52263	induction by organism of defense-related nitric oxide production in other organism involved in symbiotic interaction	P	The activation by an organism of the production of nitric oxide that occurs as part of the defense response of a second organism, where the two organisms are in a symbiotic interaction.
52264	induction by organism of defense-related reactive oxygen species production in other organism involved in symbiotic interaction	P	The activation by an organism of the production of reactive oxygen species that occurs as part of the defense response of a second organism, where the two organisms are in a symbiotic interaction.
52265	induction by organism of defense-related calcium ion flux in other organism involved in symbiotic interaction	P	The activation by an organism of a flux of calcium ions that occurs as part of the defense response of a second organism, where the two organisms are in a symbiotic interaction.
52266	negative regulation by organism of jasmonic acid-mediated defense response of other organism involved in symbiotic interaction	P	Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of the jasmonic acid-mediated defense response of a second organism, where the two organisms are in a symbiotic interaction.
52267	negative regulation by organism of defense-related jasmonic acid-mediated signal transduction pathway in other organism involved in symbiotic interaction	P	Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of jasmonic acid-mediated signal transduction pathways that occur as part of the defense response of a second organism, where the two organisms are in a symbiotic interaction.
52268	negative regulation by organism of defense-related ethylene-mediated signal transduction pathway in other organism involved in symbiotic interaction	P	Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of ethylene-mediated signal transduction pathways that occur as part of the defense response of a second organism, where the two organisms are in a symbiotic interaction.
52269	positive regulation by organism of defense-related ethylene-mediated signal transduction pathway in other organism involved in symbiotic interaction	P	Any process in which an organism activates, maintains or increases the frequency, rate or extent of ethylene-mediated signal transduction pathways that occur as part of the defense response of a second organism, where the two organisms are in a symbiotic interaction.
52270	positive regulation by organism of defense-related salicylic acid-mediated signal transduction pathway in other organism involved in symbiotic interaction	P	Any process in which an organism activates, maintains or increases the frequency, rate or extent of salicylic acid-mediated signal transduction pathways that occur as part of the defense response of a second organism, where the two organisms are in a symbiotic interaction.
52271	positive regulation by organism of defense-related jasmonic acid-mediated signal transduction pathway in other organism involved in symbiotic interaction	P	Any process in which an organism activates, maintains or increases the frequency, rate or extent of jasmonic acid-mediated signal transduction pathways that occur as part of the defense response of a second organism, where the two organisms are in a symbiotic interaction.
52272	positive regulation by organism of salicylic acid-mediated defense response of other organism involved in symbiotic interaction	P	Any process in which an organism activates, maintains or increases the frequency, rate or extent of the salicylic acid-mediated defense response of a second organism, where the two organisms are in a symbiotic interaction.
52273	positive regulation by organism of jasmonic acid-mediated defense response of other organism involved in symbiotic interaction	P	Any process in which an organism activates, maintains or increases the frequency, rate or extent of the jasmonic acid-mediated defense response of a second organism, where the two organisms are in a symbiotic interaction.
52274	positive regulation by organism of ethylene-mediated defense response of other organism involved in symbiotic interaction	P	Any process in which an organism activates, maintains or increases the frequency, rate or extent of the ethylene-mediated defense response of a second organism, where the two organisms are in a symbiotic interaction.
52275	negative regulation by organism of defense-related MAP kinase-mediated signal transduction pathway in other organism involved in symbiotic interaction	P	Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of MAP kinase-mediated signal transduction pathways that occur as part of the defense response of a second organism, where the two organisms are in a symbiotic interaction.
52276	positive regulation by organism of defense-related MAP kinase-mediated signal transduction pathway in other organism involved in symbiotic interaction	P	Any process in which an organism activates, maintains or increases the frequency, rate or extent of MAP kinase-mediated signal transduction pathways that occur as part of the defense response of a second organism, where the two organisms are in a symbiotic interaction.
52277	modulation by organism of defense-related MAP kinase-mediated signal transduction pathway in other organism involved in symbiotic interaction	P	Any process in which an organism modulates the frequency, rate or extent of MAP kinase-mediated signal transduction pathways that occur as part of the defense response of a second organism, where the two organisms are in a symbiotic interaction.
52278	negative regulation by organism of cell-mediated immune response of other organism involved in symbiotic interaction	P	Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of the cell-based immune response of a second organism, where the two organisms are in a symbiotic interaction.
52279	modulation by organism of ethylene-mediated defense response of other organism involved in symbiotic interaction	P	Any process in which an organism modulates the frequency, rate or extent of the ethylene-mediated defense response of a second organism, where the two organisms are in a symbiotic interaction.
52280	negative regulation by organism of T-cell mediated immune response of other organism involved in symbiotic interaction	P	Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of the T-cell mediated immune response of a second organism, where the two organisms are in a symbiotic interaction.
52281	negative regulation by organism of B-cell mediated immune response of other organism involved in symbiotic interaction	P	Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of the B-cell mediated immune response of a second organism, where the two organisms are in a symbiotic interaction.
52282	negative regulation by organism of defense-related callose deposition in other organism involved in symbiotic interaction	P	Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of the accumulation of callose that occurs as part of the defense response of a second organism, where the two organisms are in a symbiotic interaction.
52283	modulation by organism of jasmonic acid-mediated defense response of other organism involved in symbiotic interaction	P	Any process in which an organism modulates the frequency, rate or extent of the jasmonic acid-mediated defense response of a second organism, where the two organisms are in a symbiotic interaction.
52284	modulation by organism of salicylic acid-mediated defense response of other organism involved in symbiotic interaction	P	Any process in which an organism modulates the frequency, rate or extent of the salicylic acid-mediated defense response of a second organism, where the two organisms are in a symbiotic interaction.
52285	modulation by organism of defense-related callose deposition of other organism involved in symbiotic interaction	P	Any process in which an organism modulates the frequency, rate or extent of the accumulation of callose that occurs as part of the defense response of a second organism, where the two organisms are in a symbiotic interaction.
52286	induction by organism of resistance gene-dependent defense response of other organism involved in symbiotic interaction	P	The activation by an organism of the resistance gene-dependent defense response of a second organism, where the two organisms are in a symbiotic interaction.
52287	positive regulation by organism of defense-related calcium-dependent protein kinase pathway in other organism involved in symbiotic interaction	P	Any process in which an organism activates, maintains or increases the frequency, rate or extent of calcium-dependent protein kinase pathways that occur as part of the defense response of a second organism, where the two organisms are in a symbiotic interaction.
52288	induction by organism of induced systemic resistance in other organism involved in symbiotic interaction	P	Any process in which an organism activates induced systemic resistance, a response that confers broad spectrum systemic resistance to disease and that does not depend upon salicylic acid signaling, in a second organism, where the two organisms are in a symbiotic interaction.
52289	induction by organism of systemic acquired resistance in other organism involved in symbiotic interaction	P	Any process in which an organism activates systemic acquired resistance, a salicylic acid-mediated response that confers broad spectrum systemic resistance, in a second organism, where the two organisms are in a symbiotic interaction.
52290	induction by organism of defense-related cell wall thickening in other organism involved in symbiotic interaction	P	The activation by an organism of the thickening of cell walls that occurs as part of the defense response of a second organism, where the two organisms are in a symbiotic interaction.
52291	positive regulation by organism of defense-related callose deposition in other organism involved in symbiotic interaction	P	Any process in which an organism activates, maintains or increases the frequency, rate or extent of the accumulation of callose that occurs as part of the defense response of a second organism, where the two organisms are in a symbiotic interaction.
52292	positive regulation by organism of defense-related cell wall callose deposition in other organism involved in symbiotic interaction	P	Any process in which an organism activates, maintains or increases the frequency, rate or extent of the deposition by a second organism of callose in its cell walls, occurring as part of the defense response, where the two organisms are in a symbiotic interaction.
52293	modulation by organism of B-cell mediated immune response of other organism involved in symbiotic interaction	P	Any process in which an organism modulates the frequency, rate or extent of the B-cell mediated immune response of a second organism, where the two organisms are in a symbiotic interaction.
52294	modulation by organism of cell-mediated immune response of other organism involved in symbiotic interaction	P	Any process in which an organism modulates the frequency, rate or extent of any form of cell-based immune response of a second organism, where the two organisms are in a symbiotic interaction.
52295	modulation by organism of T-cell mediated immune response of other organism involved in symbiotic interaction	P	Any process in which an organism modulates the frequency, rate or extent of the T-cell mediated immune response of a second organism, where the two organisms are in a symbiotic interaction.
52296	modulation by organism of microbe-associated molecular pattern-induced innate immune response in other organism involved in symbiotic interaction	P	Any process that involves recognition of a microbe-associated molecular pattern, and by which an organism modulates the frequency, rate or extent of the innate immune response, the first line of defense against infection, of a second organism, where the two organisms are in a symbiotic interaction.
52297	modulation by organism of resistance gene-dependent defense response of other organism involved in symbiotic interaction	P	Any process in which an organism modulates the frequency, rate or extent of the resistance gene-dependent defense response of a second organism, where the two organisms are in a symbiotic interaction.
52298	modulation by organism of induced systemic resistance in other organism involved in symbiotic interaction	P	Any process in which an organism modulates the frequency, rate or extent of induced systemic resistance, a response that confers broad spectrum systemic resistance to disease and that does not depend upon salicylic acid signaling, in a second organism, where the two organisms are in a symbiotic interaction.
52299	modulation by organism of systemic acquired resistance in other organism involved in symbiotic interaction	P	Any process in which an organism modulates the frequency, rate or extent of systemic acquired resistance, a salicylic acid-mediated response that confers broad spectrum systemic resistance, in a second organism, where the two organisms are in a symbiotic interaction.
52300	modulation by organism of defense-related cell wall thickening in other organism involved in symbiotic interaction	P	Any process in which an organism modulates the frequency, rate or extent of the thickening of cell walls that occurs as part of the defense response of a second organism, where the two organisms are in a symbiotic interaction.
52301	modulation by organism of defense-related calcium ion flux in other organism involved in symbiotic interaction	P	Any process in which an organism modulates the frequency, rate or extent of fluxes of calcium ions that occur as part of the defense response of a second organism, where the two organisms are in a symbiotic interaction.
52302	modulation by organism of defense-related nitric oxide production in other organism involved in symbiotic interaction	P	Any process in which an organism modulates the frequency, rate or extent of the production of nitric oxide that occurs as part of the defense response of a second organism, where the two organisms are in a symbiotic interaction.
52303	modulation by organism of defense-related reactive oxygen species production in other organism involved in symbiotic interaction	P	Any process in which an organism modulates the frequency, rate or extent of the production of reactive oxygen species that occurs as part of the defense response of a second organism, where the two organisms are in a symbiotic interaction.
52304	modulation by organism of phytoalexin production in other organism involved in symbiotic interaction	P	Any process in which an organism modulates the frequency, rate or extent of production of phytoalexins that occurs as part of the defense response of a second organism, where the two organisms are in a symbiotic interaction.
52305	positive regulation by organism of innate immune response in other organism involved in symbiotic interaction	P	Any process in which an organism activates, maintains or increases the frequency, rate or extent of the innate immune response of a second organism, where the two organisms are in a symbiotic interaction.
52306	modulation by organism of innate immune response in other organism involved in symbiotic interaction	P	Any process in which an organism modulates the frequency, rate or extent of the innate immune response, the first line of defense against infection, of a second organism, where the two organisms are in a symbiotic interaction.
52307	modulation by organism of defense-related calcium-dependent protein kinase pathway in other organism involved in symbiotic interaction	P	Any process in which an organism modulates the frequency, rate or extent of calcium-dependent protein kinase signal transduction pathways that occur as part of the defense response of a second organism, where the two organisms are in a symbiotic interaction.
52308	pathogen-associated molecular pattern dependent modulation by organism of innate immune response in other organism involved in symbiotic interaction	P	Any process that involves recognition of a pathogen-associated molecular pattern, and by which an organism modulates the frequency, rate or extent of the innate immune response, the first line of defense against infection, of a second organism, where the two organisms are in a symbiotic interaction.
52309	negative regulation by organism of innate immune response in other organism involved in symbiotic interaction	P	Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of the innate immune response of a second organism, where the two organisms are in a symbiotic interaction.
52310	modulation by organism of defense-related cell wall callose deposition in other organism involved in symbiotic interaction	P	Any process in which an organism modulates the frequency, rate or extent of the accumulation of callose in cell walls that occurs as part of the defense response of a second organism, where the two organisms are in a symbiotic interaction.
52311	negative regulation by organism of defense-related cell wall callose deposition in other organism involved in symbiotic interaction	P	Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of the accumulation of callose in cell walls that occurs as part of the defense response of a second organism, where the two organisms are in a symbiotic interaction.
52312	modulation of transcription in other organism involved in symbiotic interaction	P	Any process in which an organism modulates the frequency, rate or extent of transcription in a second organism, where the two organisms are in a symbiotic interaction.
52313	modulation of nutrient release from other organism involved in symbiotic interaction	P	Any process in which an organism modulates the frequency, rate or extent of the release of nutrients from a second organism, where the two organisms are in a symbiotic interaction.
52314	phytoalexin metabolic process	P	The chemical reactions and pathways involving phytoalexins, any of a range of substances produced by plants as part of their defense response.
52315	phytoalexin biosynthetic process	P	The chemical reactions and pathways resulting in the formation of phytoalexins, any of a range of substances produced by plants as part of their defense response.
52316	phytoalexin catabolic process	P	The chemical reactions and pathways resulting in the breakdown of phytoalexins, any of a range of substances produced by plants as part of their defense response.
52317	camalexin metabolic process	P	The chemical reactions and pathways involving camalexin, an indole phytoalexin.
52318	regulation of phytoalexin metabolic process	P	Any process that modulates the frequency, rate or extent of phytoalexin metabolism, the chemical reactions and pathways involving phytoalexins, any of a range of substances produced by plants as part of their defense response.
52319	regulation of phytoalexin biosynthetic process	P	Any process that modulates the frequency, rate or extent of phytoalexin biosynthesis, the chemical reactions and pathways resulting in the formation of phytoalexins.
52320	positive regulation of phytoalexin metabolic process	P	Any process that activates, maintains or increases the frequency, rate or extent of phytoalexin metabolism, the chemical reactions and pathways involving phytoalexins.
52321	negative regulation of phytoalexin metabolic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of phytoalexin metabolism, the chemical reactions and pathways involving phytoalexins.
52322	positive regulation of phytoalexin biosynthetic process	P	Any process that activates, maintains or increases the frequency, rate or extent of phytoalexin biosynthesis, the chemical reactions and pathways resulting in the formation of phytoalexins.
52323	negative regulation of phytoalexin biosynthetic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of phytoalexin biosynthesis, the chemical reactions and pathways resulting in the formation of phytoalexins.
52324	plant-type cell wall cellulose biosynthetic process	P	The chemical reactions and pathways resulting in the formation of cellulose, a linear beta1-4 glucan of molecular mass 50-400 kDa with the pyranose units in the -4C1 conformation, as part of the organization and biogenesis of the cell wall.
52325	cell wall pectin biosynthetic process	P	The chemical reactions and pathways resulting in the formation of pectin, a polymer containing a backbone of alpha-1,4-linked D-galacturonic acid residues, as part of the organization and biogenesis of the cell wall.
52329	positive regulation by organism of phytoalexin production in other organism involved in symbiotic interaction	P	Any process in which an organism activates, maintains or increases the frequency, rate or extent of the production of phytoalexins that occurs as part of the defense response of a second organism, where the two organisms are in a symbiotic interaction.
52330	positive regulation by organism of programmed cell death in other organism involved in symbiotic interaction	P	Any process in which an organism activates, maintains or increases the frequency, rate or extent of programmed cell death in a second organism, where the two organisms are in a symbiotic interaction.
52331	hemolysis in other organism involved in symbiotic interaction	P	The cytolytic destruction of red blood cells, with the release of intracellular hemoglobin, in one organism by another, where two organisms are in a symbiotic interaction.
52332	modification by organism of membrane in other organism involved in symbiotic interaction	P	The process in which an organism effects a change in the structure or function of a cellular membrane of a second organism, where the two organisms are in a symbiotic interaction.
52333	modification by organism of cell wall of other organism involved in symbiotic interaction	P	The process in which an organism effects a change in the structure or function of the cell wall of a second organism, where the two organisms are in a symbiotic interaction.
52334	modification by organism of cytoskeleton of other organism involved in symbiotic interaction	P	The process in which an organism effects a change in the structure or function of the cytoskeleton of a second organism, where the two organisms are in a symbiotic interaction.
52335	modification by host of symbiont cytoskeleton	P	The process in which an organism effects a change in the structure or function of the symbiont cytoskeleton. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.
52336	modification by host of symbiont cell wall	P	The process in which an organism effects a change in the structure or function of the symbiont cell wall. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.
52337	modification by host of symbiont membrane	P	The process in which an organism effects a change in the structure or function of a symbiont cellular membrane. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.
52338	disruption by host of symbiont cell wall	P	The chemical reactions and pathways performed by an organism resulting in the breakdown of the symbiont cell wall. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.
52339	disruption by organism of cell wall of other organism involved in symbiotic interaction	P	The chemical reactions and pathways performed by an organism resulting in the breakdown of the cell wall of a second organism, where the two organisms are in a symbiotic interaction.
52340	catabolism by organism of cell wall cellulose in other organism involved in symbiotic interaction	P	The chemical reactions and pathways performed by an organism resulting in the breakdown of cellulose in the cell wall of a second organism, where the two organisms are in a symbiotic interaction.
52341	catabolism by organism of cell wall pectin in other organism involved in symbiotic interaction	P	The chemical reactions and pathways performed by an organism resulting in the breakdown of pectin in the cell wall of a second organism, where the two organisms are in a symbiotic interaction.
52342	catabolism by organism of cell wall chitin in other organism involved in symbiotic interaction	P	The chemical reactions and pathways performed by an organism resulting in the breakdown of chitin in the cell wall of a second organism, where the two organisms are in a symbiotic interaction.
52344	positive regulation by symbiont of host phytoalexin production	P	Any process in which an organism activates, maintains or increases the frequency, rate or extent of the production of phytoalexins as part of the defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52345	positive regulation by organism of defense-related nitric oxide production in other organism involved in symbiotic interaction	P	Any process in which an organism activates, maintains or increases the frequency, rate or extent of the production of nitric oxide that occurs as part of the defense response of a second organism, where the two organisms are in a symbiotic interaction.
52347	positive regulation by symbiont of defense-related host nitric oxide production	P	Any process in which an organism activates, maintains or increases the frequency, rate or extent of the production of nitric oxide as part of the defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52348	positive regulation by organism of defense-related reactive oxygen species production in other organism involved in symbiotic interaction	P	Any process in which an organism activates, maintains or increases the frequency, rate or extent of the production of reactive oxygen species that occurs as part of the defense response of a second organism, where the two organisms are in a symbiotic interaction.
52352	biosynthesis by host of substance in symbiont	P	The chemical reactions and pathways performed by an organism in its symbiont resulting in the formation of substances. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.
52353	catabolism by host of symbiont carbohydrate	P	The chemical reactions and pathways performed by an organism resulting in the breakdown of carbohydrate molecules within the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.
52354	catabolism by organism of carbohydrate in other organism involved in symbiotic interaction	P	The chemical reactions and pathways performed by an organism resulting in the breakdown of carbohydrate molecules within a second organism, where the two organisms are in a symbiotic interaction.
52355	catabolism by host of symbiont cell wall cellulose	P	The chemical reactions and pathways performed by an organism resulting in the breakdown of cellulose in the symbiont cell wall. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.
52356	catabolism by host of symbiont cell wall chitin	P	The chemical reactions and pathways performed by an organism resulting in the breakdown of chitin in the symbiont cell wall. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.
52357	catabolism by host of symbiont cell wall pectin	P	The chemical reactions and pathways performed by an organism resulting in the breakdown of pectin in the symbiont cell wall. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.
52358	catabolism by host of symbiont glucan	P	The chemical reactions and pathways performed by an organism resulting in the breakdown of glucan molecules within the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.
52359	catabolism by organism of glucan in other organism involved in symbiotic interaction	P	The chemical reactions and pathways performed by an organism resulting in the breakdown of glucan molecules within a second organism, where the two organisms are in a symbiotic interaction.
52360	catabolism by host of symbiont macromolecule	P	The chemical reactions and pathways performed by an organism resulting in the breakdown of macromolecules within the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.
52361	catabolism by organism of macromolecule in other organism involved in symbiotic interaction	P	The chemical reactions and pathways performed by an organism resulting in the breakdown of macromolecules within a second organism, where the two organisms are in a symbiotic interaction.
52362	catabolism by host of symbiont protein	P	The chemical reactions and pathways performed by an organism resulting in the breakdown of protein macromolecules within the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.
52363	catabolism by organism of protein in other organism involved in symbiotic interaction	P	The chemical reactions and pathways performed by an organism resulting in the breakdown of protein macromolecules within the second organism, where the two organisms are in a symbiotic interaction.
52364	catabolism by host of substance in symbiont	P	The chemical reactions and pathways performed by an organism in its symbiont resulting in the breakdown of substances. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.
52365	catabolism by host of symbiont xylan	P	The chemical reactions and pathways performed by an organism resulting in the breakdown of xylan within the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.
52366	catabolism by organism of xylan in other organism involved in symbiotic interaction	P	The chemical reactions and pathways performed by an organism resulting in the breakdown of xylan within a second organism, where the two organisms are in a symbiotic interaction.
52367	disruption by host of symbiont cellular component	P	The chemical reactions and pathways performed by an organism resulting in the breakdown of cellular components of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.
52368	disruption by organism of cellular component in other organism involved in symbiotic interaction	P	The chemical reactions and pathways performed by an organism resulting in the breakdown of cellular components of a second organism, where the two organisms are in a symbiotic interaction.
52369	positive regulation by symbiont of defense-related host reactive oxygen species production	P	Any process in which an organism activates, maintains or increases the frequency, rate or extent of the production of reactive oxygen species as part of the defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52370	entry of organism into cell of other organism by promotion of phagocytosis in other organism involved in symbiotic interaction	P	The invasion by an organism of a cell of a second organism by utilizing the second organism's phagocytosis mechanism, where the two organisms are in a symbiotic interaction.
52371	regulation by organism of entry into other organism involved in symbiotic interaction	P	Any process in which an organism modulates the frequency, rate or extent to which it enters into a second organism, where the two organisms are in a symbiotic interaction.
52372	modulation by symbiont of entry into host	P	Any process in which an organism modulates the frequency, rate or extent to which it enters into the host organism, where the two organisms are in a symbiotic interaction.
52373	negative regulation by organism of entry into other organism involved in symbiotic interaction	P	Any process in which an organism stops, prevents, or reduces the frequency, rate or extent to which it enters into a second organism, where the two organisms are in a symbiotic interaction.
52374	negative regulation by symbiont of entry into host	P	Any process in which an organism stops, prevents, or reduces the frequency, rate or extent to which it enters into the host organism, where the two organisms are in a symbiotic interaction.
52376	evasion or tolerance by organism of nitric oxide produced by other organism involved in symbiotic interaction	P	The process in which an organism avoids the effects of nitric oxide produced as a defense response by a second organism, where the two organisms are in a symbiotic interaction.
52378	evasion or tolerance by organism of phytoalexins produced by other organism involved in symbiotic interaction	P	The process in which an organism avoids the effects of phytoalexins produced as a defense response by the second organism, where the two organisms are in a symbiotic interaction.
52379	modulation by organism of entry into other organism via phagocytosis involved in symbiotic interaction	P	Any process in which an organism modulates the frequency, rate or extent to which it enters into a second organism via the phagocytotic processes of the other organism, where the two organisms are in a symbiotic interaction.
52380	modulation by symbiont of entry into host via phagocytosis	P	Any process in which an organism modulates the frequency, rate or extent to which it enters into the host, via the phagocytotic processes of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52381	tRNA dimethylallyltransferase activity	F	Catalysis of the reaction: dimethylallyl diphosphate + tRNA = diphosphate + tRNA containing 6-dimethylallyladenosine.
52382	induction by organism of innate immune response in other organism involved in symbiotic interaction	P	The activation by an organism of the innate immune response of a second organism, where the two organisms are in a symbiotic interaction.
52385	evasion or tolerance by organism of reactive oxygen species produced by other organism involved in symbiotic interaction	P	The process in which an organism avoids the effects of reactive oxygen species produced as a defense response by a second organism, where the two organisms are in a symbiotic interaction.
52386	cell wall thickening	P	A type of cell wall modification in which the cell wall is reinforced and made thicker.
52389	positive regulation by symbiont of defense-related host calcium ion flux	P	Any process in which an organism activates, maintains or increases the frequency, rate or extent of fluxes of calcium ions that occur as part of the defense response of a symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.
52390	induction by symbiont of host innate immune response	P	The activation by an organism of the innate immune response of the host organism; the innate immune response is the host's first line of defense against infection. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52391	induction by symbiont of defense-related host calcium ion flux	P	The activation by an organism of a flux of calcium ions that occurs as part of the defense response of a host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52393	induction by host of symbiont defense response	P	The activation by an organism of the defense response of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.
52403	negative regulation by host of symbiont catalytic activity	P	Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of symbiont enzyme activity. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.
52404	negative regulation by host of symbiont peptidase activity	P	Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of symbiont protease activity, the catalysis of the hydrolysis of peptide bonds in a protein. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.
52405	negative regulation by host of symbiont molecular function	P	Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of the functional activity of symbiont proteins. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.
52406	metabolism by host of symbiont carbohydrate	P	The chemical reactions and pathways performed by an organism involving carbohydrates within the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.
52407	metabolism by organism of carbohydrate in other organism involved in symbiotic interaction	P	The chemical reactions and pathways performed by an organism involving carbohydrates within a second organism, where the two organisms are in a symbiotic interaction.
52408	metabolism by host of symbiont cell wall cellulose	P	The chemical reactions and pathways performed by an organism involving cellulose in the cell wall of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.
52409	metabolism by organism of cell wall cellulose in other organism involved in symbiotic interaction	P	The chemical reactions and pathways performed by an organism involving cellulose in the cell wall of a second organism, where the two organisms are in a symbiotic interaction.
52410	metabolism by host of symbiont cell wall chitin	P	The chemical reactions and pathways performed by an organism involving chitin in the cell wall of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.
52411	metabolism by organism of cell wall chitin in other organism involved in symbiotic interaction	P	The chemical reactions and pathways performed by an organism involving chitin in the cell wall of a second organism, where the two organisms are in a symbiotic interaction.
52412	metabolism by host of symbiont cell wall pectin	P	The chemical reactions and pathways performed by an organism involving pectin in the cell wall of the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.
52413	metabolism by organism of cell wall pectin in other organism involved in symbiotic interaction	P	The chemical reactions and pathways performed by an organism involving pectin in the cell wall of a second organism, where the two organisms are in a symbiotic interaction.
52414	metabolism by host of symbiont glucan	P	The chemical reactions and pathways performed by an organism involving glucans within the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.
52415	metabolism by organism of glucan in other organism involved in symbiotic interaction	P	The chemical reactions and pathways performed by an organism involving glucans within a second organism, where the two organisms are in a symbiotic interaction.
52416	metabolism by host of symbiont macromolecule	P	The chemical reactions and pathways performed by an organism involving macromolecules within the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.
52417	metabolism by host of symbiont protein	P	The chemical reactions and pathways performed by an organism involving protein macromolecules within the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.
52418	metabolism by organism of protein in other organism involved in symbiotic interaction	P	The chemical reactions and pathways performed by an organism involving protein macromolecules within a second organism, where the two organisms are in a symbiotic interaction.
52419	metabolism by host of substance in symbiont	P	The chemical reactions and pathways performed by an organism in its symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.
52420	metabolism by host of symbiont xylan	P	The chemical reactions and pathways performed by an organism involving xylan within the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.
52421	metabolism by organism of xylan in other organism involved in symbiotic interaction	P	The chemical reactions and pathways performed by an organism involving xylan within a second organism, where the two organisms are in a symbiotic interaction.
52422	modulation by host of symbiont catalytic activity	P	The process in which a host organism effects a change in the enzyme activity of its symbiont organism.
52423	positive regulation by organism of resistance gene-dependent defense response of other organism involved in symbiotic interaction	P	Any process in which an organism activates, maintains or increases the frequency, rate or extent of the resistance gene-dependent defense response of a second organism, where the two organisms are in a symbiotic interaction.
52427	modulation by host of symbiont peptidase activity	P	The process in which an organism effects a change in symbiont peptidase activity, the catalysis of the hydrolysis of peptide bonds in a protein. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.
52428	modification by host of symbiont molecular function	P	The process in which an organism effects a change in the function of proteins in the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.
52430	modulation by host of symbiont RNA levels	P	The alteration by an organism of the levels of RNA in a symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.
52433	modulation by organism of apoptotic process in other organism involved in symbiotic interaction	P	Any process in which an organism modulates the frequency, rate or extent of programmed cell death by apoptosis in a second organism, where the two organisms are in a symbiotic interaction.
52435	modulation by host of defense-related symbiont MAP kinase-mediated signal transduction pathway	P	Any process in which an organism modulates the frequency, rate or extent of symbiont MAP kinase-mediated signal transduction pathways during the symbiont defense response. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.
52441	modulation by organism of defense-related ethylene-mediated signal transduction pathway in other organism involved in symbiotic interaction	P	Any process in which an organism modulates the frequency, rate or extent of ethylene-mediated signal transduction pathways that occur as part of the defense response of a second organism, where the two organisms are in a symbiotic interaction.
52443	modulation by organism of defense-related jasmonic acid-mediated signal transduction pathway in other organism involved in symbiotic interaction	P	Any process in which an organism modulates the frequency, rate or extent of jasmonic acid-mediated signal transduction pathways that occur as part of the defense response of a second organism, where the two organisms are in a symbiotic interaction.
52445	modulation by organism of defense-related salicylic acid-mediated signal transduction pathway in other organism involved in symbiotic interaction	P	Any process in which an organism modulates the frequency, rate or extent of salicylic acid-mediated signal transduction pathways that occur as part of the defense response of a second organism, where the two organisms are in a symbiotic interaction.
52449	modulation by organism of ethylene levels in other organism involved in symbiotic interaction	P	The alteration by an organism of the levels of ethylene in a second organism, where the two organisms are in a symbiotic interaction.
52456	modulation by organism of jasmonic acid levels in other organism involved in symbiotic interaction	P	The alteration by an organism of the levels of jasmonic acid in a second organism, where the two organisms are in a symbiotic interaction.
52460	modulation by host of nutrient release from symbiont	P	Any process in which an organism modulates the frequency, rate or extent of the release of nutrients from a symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.
52462	modulation by host of symbiont phagocytosis	P	Any process in which an organism modulates the frequency, rate or extent of phagocytosis, the engulfing by phagocytes of external particulate material, in the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.
52469	modulation by organism of salicylic acid levels in other organism involved in symbiotic interaction	P	The alteration by an organism of the levels of salicylic acid in a second organism, where the two organisms are in a symbiotic interaction.
52470	modulation by host of symbiont signal transduction pathway	P	Any process in which an organism modulates the frequency, rate or extent of the symbiont signal transduction pathways, the cascade of processes by which a signal interacts with a receptor. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.
52472	modulation by host of symbiont transcription	P	Any process in which an organism modulates the frequency, rate or extent of its symbiont's transcription.
52482	defense response by cell wall thickening	P	A type of cell wall modification, in which the cell wall is reinforced and made thicker, that occurs as part of the defense response of an organism.
52483	negative regulation by organism of entry into cell of other organism via phagocytosis involved in symbiotic interaction	P	Any process in which an organism stops or prevents itself undergoing phagocytosis into a cell in a second organism, where the two organisms are in a symbiotic interaction.
52489	negative regulation by host of symbiont programmed cell death	P	Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of programmed cell death in a symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.
52490	negative regulation by organism of programmed cell death in other organism involved in symbiotic interaction	P	Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of programmed cell death in a second organism, where the two organisms are in a symbiotic interaction.
52492	negative regulation by host of symbiont signal transduction pathway	P	Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of the symbiont signal transduction pathways, the cascade of processes by which a signal interacts with a receptor. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.
52493	negative regulation by organism of signal transduction in other organism involved in symbiotic interaction	P	Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of the second organism signal transduction pathways, the cascade of processes by which a signal interacts with a receptor, where the two organisms are in a symbiotic interaction.
52494	occlusion by host of symbiont vascular system	P	The process in which an organism reduces the flow of fluid within its symbiont's vascular system, the vessels and tissue that carry or circulate fluids, such as blood, lymph or sap, through the body of an animal or plant. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.
52495	occlusion by organism of vascular system in other organism involved in symbiotic interaction	P	The process in which an organism reduces the flow of fluid within its second organism's vascular system, the vessels and tissue that carry or circulate fluids, such as blood, lymph or sap, through the body of an animal or plant, where the two organisms are in a symbiotic interaction.
52496	occlusion by host of symbiont xylem	P	The process in which an organism reduces the flow of fluid within the symbiont xylem, the tissue in plants that carries water and nutrients up from the roots to the shoot and leaves. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.
52497	occlusion by organism of xylem in other organism involved in symbiotic interaction	P	The process in which an organism reduces the flow of fluid within the xylem, the tissue in plants that carries water and nutrients up from the roots to the shoot and leaves, of a second organism, where the two organisms are in a symbiotic interaction.
52501	positive regulation by organism of apoptotic process in other organism involved in symbiotic interaction	P	Any process in which an organism activates, maintains or increases the frequency, rate or extent of programmed cell death by apoptosis in a second organism, where the two organisms are in a symbiotic interaction.
52502	positive regulation by host of defense-related symbiont MAP kinase-mediated signal transduction pathway	P	Any process in which an organism activates, maintains or increases the frequency, rate or extent of symbiont MAP kinase-mediated signal transduction pathways during the symbiont defense response. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.
52509	positive regulation by symbiont of host defense response	P	Any process in which an organism activates, maintains or increases the frequency, rate or extent of the defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52510	positive regulation by organism of defense response of other organism involved in symbiotic interaction	P	Any process in which an organism activates, maintains or increases the frequency, rate or extent of the defense response of a second organism, where the two organisms are in a symbiotic interaction.
52513	positive regulation by organism of hormone or growth regulator levels in other organism involved in symbiotic interaction	P	The increase by an organism of the levels of hormones or growth regulators in a second organism, where the two organisms are in a symbiotic interaction.
52519	positive regulation by host of nutrient release from symbiont	P	Any process in which an organism activates, maintains or increases the frequency, rate or extent of the release of nutrients from a symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.
52520	positive regulation by organism of nutrient release from other organism involved in symbiotic interaction	P	Any process in which an organism activates, maintains or increases the frequency, rate or extent of the release of nutrients from a second organism, where the two organisms are in a symbiotic interaction.
52521	positive regulation by host of symbiont phagocytosis	P	Any process in which an organism activates, maintains or increases the frequency, rate or extent of phagocytosis, the engulfing by phagocytes of external particulate material, in the symbiont organism. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.
52522	positive regulation by organism of phagocytosis in other organism involved in symbiotic interaction	P	Any process in which an organism activates, maintains or increases the frequency, rate or extent of phagocytosis, the engulfing by phagocytes of external particulate material, in the second organism, where the two organisms are in a symbiotic interaction.
52525	positive regulation by host of symbiont signal transduction pathway	P	Any process in which an organism activates, maintains or increases the frequency, rate or extent of the symbiont signal transduction pathways, the cascade of processes by which a signal interacts with a receptor. The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.
52526	positive regulation by organism of signal transduction in other organism involved in symbiotic interaction	P	Any process in which an organism activates, maintains or increases the frequency, rate or extent of the second organism signal transduction pathways, the cascade of processes by which a signal interacts with a receptor, where the two organisms are in a symbiotic interaction.
52527	positive regulation by symbiont of host resistance gene-dependent defense response	P	Any process in which an organism activates, maintains or increases the frequency, rate or extent of the resistance gene-dependent defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52532	positive regulation by organism of induced systemic resistance in other organism involved in symbiotic interaction	P	Any process in which an organism activates, maintains or increases the frequency, rate or extent of induced systemic resistance, a response that confers broad spectrum systemic resistance to disease and that does not depend upon salicylic acid signaling, in a second organism, where the two organisms are in a symbiotic interaction.
52533	positive regulation by symbiont of host induced systemic resistance	P	Any process in which an organism activates, maintains or increases the frequency, rate or extent of induced systemic resistance in the host organism; induced systemic resistance is a response that confers broad spectrum systemic resistance to disease and that does not depend upon salicylic acid signaling. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52535	positive regulation by organism of systemic acquired resistance in other organism involved in symbiotic interaction	P	Any process in which an organism activates, maintains or increases the frequency, rate or extent of systemic acquired resistance organism; systemic acquired resistance is a salicylic acid-mediated response that confers broad spectrum systemic resistance, in a second organism, where the two organisms are in a symbiotic interaction.
52537	positive regulation by symbiont of host systemic acquired resistance	P	Any process in which an organism activates, maintains or increases the frequency, rate or extent of systemic acquired resistance in the host organism; systemic acquired resistance is a salicylic acid-mediated response that confers broad spectrum systemic resistance. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52538	positive regulation by organism of defense-related cell wall thickening in other organism involved in symbiotic interaction	P	Any process in which an organism activates, maintains or increases the frequency, rate or extent of the thickening of cell walls that occurs as part of the defense response of a second organism, where the two organisms are in a symbiotic interaction.
52539	positive regulation by symbiont of defense-related host cell wall thickening	P	Any process in which an organism activates, maintains or increases the frequency, rate or extent of a host process resulting in the thickening of its cell walls, occurring as part of the defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52541	plant-type cell wall cellulose metabolic process	P	The chemical reactions and pathways involving cellulose, a linear beta1-4 glucan of molecular mass 50-400 kDa with the pyranose units in the -4C1 conformation, as part of the organization and biogenesis of the cell wall.
52542	defense response by callose deposition	P	Any process in which callose is transported to, and/or maintained in, a specific location during the defense response. Callose is a linear 1,3-beta-d-glucan formed from UDP-glucose and is found in certain plant cell walls.
52543	callose deposition in cell wall	P	Any process in which callose is transported to, and/or maintained in, the cell wall. Callose is a linear 1,3-beta-d-glucan formed from UDP-glucose and is found in certain plant cell walls.
52544	defense response by callose deposition in cell wall	P	Any process in which callose is transported to, and/or maintained in, the cell wall during the defense response. Callose is a linear 1,3-beta-d-glucan formed from UDP-glucose and is found in certain plant cell walls.
52545	callose localization	P	Any process in which callose is transported to, and/or maintained in, a specific location. Callose is a linear 1,3-beta-d-glucan formed from UDP-glucose and is found in certain plant cell walls.
52546	cell wall pectin metabolic process	P	The chemical reactions and pathways involving pectin, a polymer containing a backbone of alpha-1,4-linked D-galacturonic acid residues, as part of the organization and biogenesis of the cell wall.
52547	regulation of peptidase activity	P	Any process that modulates the frequency, rate or extent of peptidase activity, the hydrolysis of peptide bonds within proteins.
52548	regulation of endopeptidase activity	P	Any process that modulates the frequency, rate or extent of endopeptidase activity, the endohydrolysis of peptide bonds within proteins.
52549	response to phytoalexin production by other organism involved in symbiotic interaction	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of phytoalexins produced as a defense response by a second organism, where the two organisms are in a symbiotic interaction.
52550	response to defense-related reactive oxygen species production by other organism involved in symbiotic interaction	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of reactive oxygen species produced as a defense response by a second organism, where the two organisms are in a symbiotic interaction.
52551	response to defense-related nitric oxide production by other organism involved in symbiotic interaction	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of nitric oxide produced as a defense response by a second organism, where the two organisms are in a symbiotic interaction.
52552	modulation by organism of immune response of other organism involved in symbiotic interaction	P	Any process in which an organism modulates the frequency, rate or extent of the immune response of a second organism, where the two organisms are in a symbiotic interaction. The immune response is any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat.
52553	modulation by symbiont of host immune response	P	Any process in which an organism modulates the frequency, rate or extent of the immune response of the host organism; the immune response is any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52555	positive regulation by organism of immune response of other organism involved in symbiotic interaction	P	Any process in which an organism activates, maintains or increases the frequency, rate or extent of the immune response of a second organism, where the two organisms are in a symbiotic interaction. The immune response is any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat.
52556	positive regulation by symbiont of host immune response	P	Any process in which an organism activates, maintains or increases the frequency, rate or extent of the immune response of the host organism; the immune response is any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52558	induction by organism of immune response of other organism involved in symbiotic interaction	P	Any process in which an organism activates the immune response of a second organism, where the two organisms are in a symbiotic interaction. The immune response is any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat.
52559	induction by symbiont of host immune response	P	Any process in which an organism activates the immune response of the host organism; the immune response is any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52561	negative regulation by organism of immune response of other organism involved in symbiotic interaction	P	Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of the immune response of a second organism, where the two organisms are in a symbiotic interaction. The immune response is any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat.
52562	negative regulation by symbiont of host immune response	P	Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of the immune response of the host organism; the immune response is any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52564	response to immune response of other organism involved in symbiotic interaction	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detecting the immune response of a second organism, where the two organisms are in a symbiotic interaction.
52565	response to defense-related host nitric oxide production	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of nitric oxide produced as part of the defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52566	response to host phytoalexin production	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of phytoalexins produced as part of the defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52567	response to defense-related host reactive oxygen species production	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of reactive oxygen species produced as part of the defense response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52572	response to host immune response	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detecting the immune response of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
52573	UDP-D-galactose metabolic process	P	The chemical reactions and pathways involving UDP-D-galactose, a substance composed of D-galactose in glycosidic linkage with guanosine diphosphate.
52574	UDP-D-galactose biosynthetic process	P	The chemical reactions and pathways resulting in the formation of UDP-D-galactose, a substance composed of D-galactose in glycosidic linkage with guanosine diphosphate.
52575	carbohydrate localization	P	Any process in which a carbohydrate is transported to, or maintained in, a specific location. Carbohydrates are any of a group of organic compounds based of the general formula Cx(H2O)y.
52576	carbohydrate storage	P	The accumulation and maintenance in cells or tissues of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y.
52577	germacrene-D synthase activity	F	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = (-)-germacrene D + diphosphate.
52578	alpha-farnesene synthase activity	F	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = (E,E)-alpha-farnesene + diphosphate.
52579	(+)-pulegone reductase, (+)-isomenthone as substrate, activity	F	Catalysis of the reaction: (+)-isomenthone + NADP+ = (+)-pulegone + NADPH + H+.
52580	(+)-pulegone reductase, (-)-menthone as substrate, activity	F	Catalysis of the reaction: (-)-menthone + NADP+ = (+)-pulegone + NADPH + H+.
52581	(-)-isopiperitenone reductase activity	F	Catalysis of the reaction: (6R)-isoperitenone + H(+) + NADPH = (2R,5R)-isopulegone + NADP(+).
52582	(+)-menthofuran synthase activity	F	Catalysis of the reaction: (R)-pulegone + H(+) + NADPH + O(2) = (R)-menthofuran + 2 H(2)O + NADP(+).
52583	oxidoreductase activity, acting on halogen in donors	F	Catalysis of an oxidation-reduction in which a halogen in the donor substance acts as a hydrogen or electron donor and reduces a hydrogen or electron acceptor.
52584	oxidoreductase activity, acting on halogen in donors, with NAD or NADP as acceptor	F	Catalysis of an oxidation-reduction in which a halogen in the donor substance acts as a hydrogen or electron donor and reduces NAD or NADP.
52585	oxidoreductase activity, acting on the CH-NH2 group of donors, with a quinone or similar compound as acceptor	F	Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH2 group acts as a hydrogen or electron donor and reduces a quinone or similar compound.
52586	oxidoreductase activity, acting on other nitrogenous compounds as donors, with a quinone or similar compound as acceptor	F	Catalysis of an oxidation-reduction (redox) reaction in which a nitrogenous group, excluding NH and NH2 groups, acts as a hydrogen or electron donor and reduces a quinone or similar compound.
52587	diacetyl reductase ((R)-acetoin forming) activity	F	Catalysis of the reaction: (R)-acetoin + NAD(+) = diacetyl + H(+) + NADH.
52588	diacetyl reductase ((S)-acetoin forming) activity	F	Catalysis of the reaction: (S)-acetoin + NAD(+) = diacetyl + H(+) + NADH.
52589	malate dehydrogenase (menaquinone) activity	F	Catalysis of the reaction: (S)-malate + a menaquinone = oxaloacetate + a menaquinol.
52590	sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity	F	Catalysis of the reaction: sn-glycerol 3-phosphate + a ubiquinone = glycerone phosphate + a ubiquinol.
52591	sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity	F	Catalysis of the reaction: sn-glycerol 3-phosphate + ubiquinone-8 = glycerone phosphate + ubiquinol-8.
52592	oxidoreductase activity, acting on CH or CH2 groups, with an iron-sulfur protein as acceptor	F	Catalysis of an oxidation-reduction (redox) reaction in which a CH2 group acts as a hydrogen or electron donor and reduces an iron-sulfur protein.
52593	tryptamine:oxygen oxidoreductase (deaminating) activity	F	Catalysis of the reaction: tryptamine + H2O + O2 = NH3 + indole acetaldehyde + hydrogen peroxide + H+.
52594	aminoacetone:oxygen oxidoreductase(deaminating) activity	F	Catalysis of the reaction: aminoacetone + H2O + O2 = methylglyoxal + NH3 + hydrogen peroxide + H+.
52595	aliphatic-amine oxidase activity	F	Catalysis of the reaction: an aliphatic amine + H2O + O2 = an aldehyde + NH3 + hydrogen peroxide + H+.
52596	phenethylamine:oxygen oxidoreductase (deaminating) activity	F	Catalysis of the reaction: phenylethylamine + O2 + H2O = phenylacetaldehyde + NH3 + hydrogen peroxide + H+.
52597	diamine oxidase activity	F	Catalysis of the reaction: a diamine + H2O + O2 = a monoamine + NH3 + hydrogen peroxide.
52598	histamine oxidase activity	F	Catalysis of the reaction: histamine + H2O + O2 = imidazole-4-acetaldehyde + NH3 + hydrogen peroxide + H+.
52599	methylputrescine oxidase activity	F	Catalysis of the reaction: N-methylputrescine + H2O + O2 = N-methylaminobutanal + NH3 + hydrogen peroxide + H+.
52600	propane-1,3-diamine oxidase activity	F	Catalysis of the reaction: propane-1,3-diamine + H2O + O2 = 3-aminopropanal + NH3 + hydrogen peroxide + H+.
52601	(S)-limonene 1,2-monooxygenase activity	F	Catalysis of the reaction: (4S)-limonene + NAD(P)H + H+ + O2 = NAD(P)+ + H2O + (4S)-limonene-1,2-epoxide.
52602	4-chloronitrobenzene nitroreductase activity	F	Catalysis of the reaction: 4-chloronitrobenzene + NADPH + H+ = 1-chloro-4-nitrosobenzene + NADP+ + H2O.
52603	1-chloro-4-nitrosobenzene nitroreductase activity	F	Catalysis of the reaction: 1-chloro-4-nitrosobenzene + NADPH + H+ = 1-chloro-4-hydroxylaminobenzene + NADP+ + H2O.
52604	delta-tocopherol cyclase activity	F	Catalysis of the reaction: 2-methyl-6-phytyl-1,4-benzoquinone = delta-tocopherol.
52605	gamma-tocopherol cyclase activity	F	Catalysis of the reaction: 2,3-dimethyl-6-phytyl-1,4-benzoquinone = gamma-tocopherol.
52606	chlorophyllide a oxygenase activity	F	Catalysis of the reaction: chlorophyllide a + NADPH + O2 + 2 H+ = 7-hydroxychlorophyllide a + NADP+ + H2O.
52607	7-hydroxy-chlorophyllide a oxygenase activity	F	Catalysis of the reaction: 7-hydroxychlorophyllide a + NADPH + O2 + H+ = chlorophyllide b + NADP+ + 2 H2O.
52608	echinenone 3-hydroxylase activity	F	Catalysis of the reaction: echinenone + a reduced electron acceptor + oxygen = 3-hydroxyechinenone + an oxidized electron acceptor + H2O.
52609	4-ketotorulene 3-hydroxylase activity	F	Catalysis of the reaction: 4-ketotorulene + a reduced electron acceptor + oxygen = 3-hydroxy-4-ketotorulene + an oxidized electron acceptor + H2O.
52610	beta-cryptoxanthin hydroxylase activity	F	Catalysis of the reaction: beta-cryptoxanthin + a reduced electron acceptor + oxygen = zeaxanthin + an oxidized electron acceptor + H2O.
52611	beta-carotene 3-hydroxylase activity	F	Catalysis of the reaction: beta-carotene + a reduced electron acceptor + oxygen = beta-cryptoxanthin + an oxidized electron acceptor + H2O.
52612	adonirubin 3-hydroxylase activity	F	Catalysis of the reaction: adonirubin + a reduced electron acceptor + oxygen = 3S,3'S-astaxanthin + an oxidized electron acceptor + H2O.
52613	canthaxanthin 3-hydroxylase activity	F	Catalysis of the reaction: canthaxanthin + a reduced electron acceptor + oxygen = adonirubin + an oxidized electron acceptor + H2O.
52614	uracil oxygenase activity	F	Catalysis of the reaction: uracil + NADH + O2 + H+ = ureidoacrylate peracid + NAD+. Ureidoacrylate peracid is spontaneously reduced by NADH to form ureidoacrylate.
52615	ent-kaurene oxidase activity	F	Catalysis of the reaction: H+ + NADPH + ent-kaur-16-ene + oxygen = H2O + NADP+ + ent-kaur-16-en-19-ol.
52616	ent-kaur-16-en-19-ol oxidase activity	F	Catalysis of the reaction: H+ + NADPH + ent-kaur-16-en-19-ol + oxygen = 2 H2O + NADP+ + ent-kaur-16-en-19-al.
52617	ent-kaur-16-en-19-al oxidase activity	F	Catalysis of the reaction: NADPH + ent-kaur-16-en-19-al + oxygen = H2O + NADP+ + ent-kaurenoate.
52618	coenzyme F420-0:L-glutamate ligase activity	F	Catalysis of the reaction: GTP + L-glutamate + factor F420-0 = GDP + H+ + factor gamma-F420-1 + phosphate.
52619	coenzyme F420-1:gamma-L-glutamate ligase activity	F	Catalysis of the reaction: GTP + L-glutamate + factor gamma-F420-1 = GDP + H+ + factor gamma-F420-2 + phosphate.
52620	thymine dehydrogenase activity	F	Catalysis of the reaction: H2O + thymine + acceptor = 5-methyl-barbiturate + donor-H2.
52621	diguanylate cyclase activity	F	Catalysis of the reaction: 2 GTP = cyclic di-3',5'-guanylate + 2 diphosphate + 2 H(+).
52622	ATP dimethylallyltransferase activity	F	Catalysis of the reaction: delta(2)-isopentenyl diphosphate + ATP = diphosphate + N6-(delta(2)-isopentenyl)adenosine 5'-triphosphate.
52623	ADP dimethylallyltransferase activity	F	Catalysis of the reaction: delta2-isopentenyl diphosphate + ADP = diphosphate + N6-(delta(2)-isopentenyl)adenosine 5'-diphosphate.
52624	2-phytyl-1,4-naphthoquinone methyltransferase activity	F	Catalysis of the reaction: demethylphylloquinone + S-adenosyl-L-methionine = phylloquinone + S-adenosyl-L-homocysteine + H+.
52625	4-aminobenzoate amino acid synthetase activity	F	Catalysis of the reaction: 4-aminobenzoate + ATP + amino acid = 4-aminobenzoyl amino acid conjugate + AMP + diphosphate.
52626	benzoate amino acid synthetase activity	F	Catalysis of the reaction: benzoate + ATP + amino acid = benzoyl amino acid conjugate + AMP + diphosphate.
52627	vanillate amino acid synthetase activity	F	Catalysis of the reaction: vanillate + ATP + amino acid = vanillate amino acid conjugate + AMP + diphosphate.
52628	4-hydroxybenzoate amino acid synthetase activity	F	Catalysis of the reaction: 4-hydroxybenzoate + ATP + amino acid = 4-hydroxybenzoyl amino acid conjugate + AMP + diphosphate.
52629	phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity	F	Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate + H2O = a 1-phosphatidyl-1D-myo-inositol 5-phosphate + phosphate + 2 H+.
52630	UDP-N-acetylgalactosamine diphosphorylase activity	F	Catalysis of the reaction: UTP + N-acetyl-alpha-D-galactosamine 1-phosphate = diphosphate + UDP-N-acetyl-D-galactosamine.
52631	sphingolipid delta-8 desaturase activity	F	Catalysis of the formation of a double bond between C8 and C9 of the long chain base of a sphingolipid. For example, sphinganine (d18:0) = 8-sphingenine (d18:1delta8); phytosphinganine (t18:0) = 8-phytosphingenine (t18:1delta8); and 4-sphingenine (18:1delta4) = 4,8-sphingadienine (d18:2delta4,8).
52633	isocitrate hydro-lyase (cis-aconitate-forming) activity	F	Catalysis of the reaction: cis-aconitate + H2O = isocitrate.
52634	C-19 gibberellin 2-beta-dioxygenase activity	F	Catalysis of the reaction: a C-19 gibberellin + 2-oxoglutarate + O2 = a C-19 2-beta-hydroxygibberellin + succinate + CO2. C-19 gibberellin refers to a gibberellin with nineteen carbons.
52635	C-20 gibberellin 2-beta-dioxygenase activity	F	Catalysis of the reaction: a C-20 gibberellin + 2-oxoglutarate + O2 = a C-20 2-beta-hydroxygibberellin + succinate + CO2. C-20 gibberellin refers to a gibberellin with twenty carbons.
52636	arabinosyltransferase activity	F	Catalysis of the transfer of an arabinosyl group from one compound (donor) to another (acceptor).
52637	delta 3-trans-hexadecenoic acid phosphatidylglycerol desaturase activity	F	Catalysis of the reaction: 1-18:3-3-16:0-phosphatidylglycerol = 1-18:3-3-trans-16:1-phosphatidylglycerol + 2 H+. This reaction is the formation of a trans double bond between carbon 3 and carbon 4 (counting from the carboxyl end) of palmitic acid, which is specifically esterified to the sn-2 glyceryl carbon of phosphatidylglycerol.
52638	indole-3-butyrate beta-glucosyltransferase activity	F	Catalysis of the reaction: indole-3-butyrate + UDP-D-glucose = indole-3-butyryl-beta-1-D-glucose + UDP.
52639	salicylic acid glucosyltransferase (ester-forming) activity	F	Catalysis of the reaction: salicylic acid + UDP-glucose = salicylic acid glucose ester + UDP.
52640	salicylic acid glucosyltransferase (glucoside-forming) activity	F	Catalysis of the reaction: salicylic acid + UDP-glucose = salicylic acid 2-O-glucoside + UDP.
52641	benzoic acid glucosyltransferase activity	F	Catalysis of the reaction: benzoic acid + UDP-glucose = benzoic acid glucose ester + UDP.
52642	lysophosphatidic acid phosphatase activity	F	Catalysis of the reaction: lysophosphatidic acid + H2O = phosphate + monoacylglycerol.
52643	chlorophyllide metabolic process	P	The chemical reactions and pathways involving chlorophyllides, any chlorophyll lacking the terpenoid side chain such as phytyl or farnesyl.
52644	chlorophyllide a metabolic process	P	The chemical reactions and pathways involving chlorophyllide a, a chlorophyll lacking the terpenoid side chain, which is the functional parent of chlorophyll a.
52645	F420-0 metabolic process	P	The chemical reactions and pathways involving F420-0 (5-O-{[(1S)-1-carboxyethoxy](hydroxy)phosphoryl}-1-deoxy-1-(8-hydroxy-2,4-dioxo-2H-pyrimido[4,5-b]quinolin-10(4H)-yl)-D-ribitol), the fragment of coenzyme F420 remaining after formal hydrolytic removal of all of the glutamate residues.
52646	alditol phosphate metabolic process	P	The chemical reactions and pathways involving alditol phosphates, any phosphorylated polyhydric alcohol derived from the acyclic form of a monosaccharide by reduction of its aldehyde or keto group to an alcoholic group.
52647	pentitol phosphate metabolic process	P	The chemical reactions and pathways involving pentitol phosphates, any phosphorylated alditol with a chain of five carbon atoms in the molecule.
52648	ribitol phosphate metabolic process	P	The chemical reactions and pathways involving ribitol phosphates, any phosphorylated form of ribitol, the pentitol derived formally by reduction of the -CHO group of either D- or L-ribose.
52649	coenzyme gamma-F420-2 metabolic process	P	The chemical reactions and pathways involving coenzyme gamma-F420-2 (F420-2; coenzyme F420; N-{N-[O-(7,8-didemethyl-8-hydroxy-5-deazariboflavin phospho)-(S)-lactyl]-gamma-L-glutamyl}-L-glutamate), the amide obtained by formal condensation of the carboxylic acid group of F420-0 with the amino group of L-gamma-glutamyl-L-glutamic acid.
52650	NADP-retinol dehydrogenase activity	F	Catalysis of the reaction: all-trans-retinol + NADP+ = all-trans-retinal + NADPH + H+.
52651	monoacylglycerol catabolic process	P	The chemical reactions and pathways resulting in the breakdown of monoacylglycerol, any ester of glycerol in which any one of its hydroxyl groups has been acylated with a fatty acid, the other being non-esterified.
52652	cyclic purine nucleotide metabolic process	P	The chemical reactions and pathways involving a cyclic nucleotide, a nucleotide in which the phosphate group is in diester linkage to two positions on the sugar residue and the base is a purine.
52653	3',5'-cyclic diguanylic acid metabolic process	P	The chemical reactions and pathways involving 3',5'-cyclic diguanylic acid, a cyclic purine dinucleotide in which the base groups are guanine.
52654	L-leucine transaminase activity	F	Catalysis of the reaction: 2-oxoglutarate + L-leucine = 4-methyl-2-oxopentanoate + L-glutamatic acid.
52655	L-valine transaminase activity	F	Catalysis of the reaction: 2-oxoglutarate + L-valine = 3-methyl-2-oxobutanoic acid + L-glutamatic acid.
52656	L-isoleucine transaminase activity	F	Catalysis of the reaction: 2-oxoglutarate + L-isoleucine = (S)-3-methyl-2-oxopentanoic acid + L-glutamic acid.
52657	guanine phosphoribosyltransferase activity	F	Catalysis of the reaction: GMP + diphosphate = guanine + 5-phospho-alpha-D-ribose 1-diphosphate.
52658	inositol-1,4,5-trisphosphate 5-phosphatase activity	F	Catalysis of the reaction: 1D-myo-inositol 1,4,5-trisphosphate + H2O = 1D-myo-inositol 1,4-bisphosphate + phosphate.
52659	inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity	F	Catalysis of the reaction: 1D-myo-inositol 1,3,4,5-tetrakisphosphate + H2O = 1D-myo-inositol 1,3,4-trisphosphate + phosphate.
52660	R-lactaldehyde reductase activity	F	Catalysis of the reaction: (R)-propane-1,2-diol + NAD+ = (R)-lactaldehyde + NADH + H+.
52661	S-lactaldehyde reductase activity	F	Catalysis of the reaction: (S)-propane-1,2-diol + NAD+ = (S)-lactaldehyde + NADH + H+.
52662	zeaxanthin epoxidase activity	F	Catalysis of the reaction: zeaxanthin + NAD(P)H + H+ + O2 = antheraxanthin + NAD(P)+ + H2O.
52663	antheraxanthin epoxidase activity	F	Catalysis of the reaction: antheraxanthin + NAD(P)H + H+ + O2 = all-trans-violaxanthin + NAD(P)+ + H2O.
52664	nitroalkane oxidase activity	F	Catalysis of the reaction: nitroalkane + H2O + O2 = an aldehyde or ketone + nitrite + H2O2.
52665	tRNA (uracil-2'-O-)-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing 2'-O-methyluracil.
52666	tRNA (cytosine-2'-O-)-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing 2'-O-methylcytosine.
52667	phosphomethylethanolamine N-methyltransferase activity	F	Catalysis of the reaction: N-methylethanolamine phosphate + S-adenosyl-L-methionine = N,N-dimethylethanolamine phosphate + S-adenosyl-L-homocysteine + H(+).
52668	farnesol kinase activity	F	Catalysis of the reaction: farnesol + nucleoside triphosphate = farnesyl monophosphate + nucleoside diphosphate.
52669	CTP:2-trans,-6-trans-farnesol kinase activity	F	Catalysis of the reaction: 2-trans,-6-trans-farnesol + CTP = 2-trans,-6-trans-farnesyl monophosphate + CDP + H+.
52670	geraniol kinase activity	F	Catalysis of the reaction: geraniol + nucleoside triphosphate = geranyl monophosphate + nucleoside diphosphate.
52671	geranylgeraniol kinase activity	F	Catalysis of the reaction: geranylgeraniol + nucleoside triphosphate = all-trans-geranyl-geranyl monophosphate + nucleoside diphosphate.
52672	CTP:geranylgeraniol kinase activity	F	Catalysis of the reaction: geranylgeraniol + CTP = all-trans-geranyl-geranyl monophosphate + CDP.
52673	prenol kinase activity	F	Catalysis of the reaction: prenol + nucleoside triphosphate = prenyl phosphate + nucleoside diphosphate activity.
52674	ent-pimara-9(11),15-diene synthase activity	F	Catalysis of the reaction: ent-copalyl diphosphate = ent-pimara-9(11),15-diene + diphosphate.
52675	3-methylbutanol:NADP oxidoreductase activity	F	Catalysis of the reaction: 3-methylbutanol + NADP+ = 3-methylbutanal + NADPH + H+. 3-methylbutanal is also known as isovaleraldehyde.
52676	3-methylbutanol:NAD oxidoreductase activity	F	Catalysis of the reaction: 3-methylbutanol + NAD+ = 3-methylbutanal + NADH + H+. 3-methylbutanal is also known as isovaleraldehyde.
52677	D-arabinitol dehydrogenase, D-xylulose forming (NADP+) activity	F	Catalysis of the reaction: D-arabinitol + NADP+ = D-xylulose + NADPH + H+.
52678	levopimaradiene synthase activity	F	Catalysis of the reaction: (+)-copalyl diphosphate = abieta-8(14),12-diene + diphosphate.
52679	terpentetriene synthase activity	F	Catalysis of the reaction: terpentedienyl diphosphate = diphosphate + terpentetriene.
52680	epi-isozizaene synthase activity	F	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = (+)-epi-isozizaene + diphosphate.
52681	alpha-bisabolene synthase activity	F	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = (E,R)-alpha-bisabolene + diphosphate.
52682	epi-cedrol synthase activity	F	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate + H2O = epi-cedrol + diphosphate.
52683	(Z)-gamma-bisabolene synthase activity	F	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = (Z)-gamma-bisabolene + diphosphate.
52684	L-serine hydro-lyase (adding indole, L-tryptophan-forming) activity	F	Catalysis of the reaction: indole + L-serine = L-tryptophan + H2O.
52685	perillic acid:CoA ligase (ADP-forming) activity	F	Catalysis of the reaction: perillic acid + CoA-SH + ATP = H2O + ADP + phosphate + perillyl-CoA.
52686	perillic acid:CoA ligase (AMP-forming) activity	F	Catalysis of the reaction: perillic acid + CoA-SH + ATP = H2O + AMP + diphosphate + perillyl-CoA.
52687	(3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (ADP-forming) activity	F	Catalysis of the reaction: (3R)-3-isopropenyl-6-oxoheptanoate + CoA-SH + ATP = H2O + ADP + phosphate + (3R)-3-isopropenyl-6-oxoheptanoyl-CoA.
52688	(3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (AMP-forming) activity	F	Catalysis of the reaction: (3R)-3-isopropenyl-6-oxoheptanoate + CoA-SH + ATP = H2O + AMP + diphosphate + (3R)-3-isopropenyl-6-oxoheptanoyl-CoA.
52689	carboxylic ester hydrolase activity	F	Catalysis of the hydrolysis of a carboxylic ester bond.
52690	trichloro-p-hydroquinone reductive dehalogenase activity	F	Catalysis of the reaction: 2,3,6-trichlorohydroquinone + 2 glutathione = 2,6-dichlorohydroquinone + glutathione disulfide + HCl.
52691	UDP-arabinopyranose mutase activity	F	Catalysis of the reaction: UDP-beta-L-arabinofuranose = UDP-beta-L-arabinopyranose.
52692	raffinose alpha-galactosidase activity	F	Catalysis of the reaction: raffinose + H2O = alpha-D-galactose + sucrose.
52693	epoxyqueuosine reductase activity	F	Catalysis of the reaction: epoxyqueuosine in tRNA + reductant = queuosine in tRNA + oxidised reductant.
52694	jasmonoyl-isoleucine-12-hydroxylase activity	F	Catalysis of the reaction: jasmonoyl-isoleucine + NADPH + H+ + O2 = 12-hydroxy-jasmonoyl-isoleucine + NADP+ + H2O.
52695	cellular glucuronidation	P	The modification of an organic chemical by the conjugation of glucuronic acid. The substances resulting from glucuronidation are known as glucuronosides (or glucuronides) and are often much more water-soluble than the non-glucuronic acid-containing precursor.
52696	flavonoid glucuronidation	P	The modification of a flavonoid by the conjugation of glucuronic acid. The resultant flavonoid glucuronosides are often much more water-soluble than the precursor.
52697	xenobiotic glucuronidation	P	The modification of a xenobiotic substance by the conjugation of glucuronic acid. The resultant glucuronosides are often much more water-soluble than the xenobiotic precursor, enabling efficient excretion.
52698	ergothioneine metabolic process	P	The chemical reactions and pathways involving ergothioneine, a naturally occurring metabolite of histidine with antioxidant properties.
52699	ergothioneine biosynthetic process	P	The chemical reactions and pathways resulting in the formation of ergothioneine, a naturally occurring metabolite of histidine with antioxidant properties.
52700	ergothioneine catabolic process	P	The chemical reactions and pathways resulting in the breakdown of ergothioneine, a naturally occurring metabolite of histidine with antioxidant properties.
52701	cellular modified histidine metabolic process	P	The chemical reactions and pathways involving compounds derived from histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid.
52702	cellular modified histidine catabolic process	P	The chemical reactions and pathways resulting in the breakdown of compounds derived from histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid.
52703	cellular modified histidine biosynthetic process	P	The chemical reactions and pathways resulting in the formation of compounds derived from histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid.
52704	ergothioneine biosynthesis from histidine via N-alpha,N-alpha,N-alpha-trimethyl-L-histidine	P	The pathway resulting in the formation of ergothioneine from histidine. Histidine undergoes three methylations by a histidine-alpha-N-methyltransferase (EC:2.1.1.44) to form N-alpha,N-alpha,N-alpha-trimethyl-L-histidine (also known as hercynine or histidine betaine). N-alpha,N-alpha,N-alpha-trimethyl-L-histidine is modified by the ligation of gamma-glutamyl-cysteine and oxygen; this intermediate undergoes further modification by the removal of glutamate to produce hercynylcysteine sulfoxide. Finally, a beta-lyase acts on this compound, removing pyruvate, ammonia and oxygen to produce ergothioneine.
52705	methylhistidine N-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + N-alpha-methyl-L-histidine = S-adenosyl-L-homocysteine + N-alpha,N-alpha-dimethyl-L-histidine.
52706	histidine N-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + L-histidine = S-adenosyl-L-homocysteine + N-alpha,N-alpha,N-alpha-trimethyl-L-histidine.
52707	N-alpha,N-alpha,N-alpha-trimethyl-L-histidine biosynthesis from histidine	P	The pathway resulting in the formation of N-alpha,N-alpha,N-alpha-trimethyl-L-histidine from histidine. Histidine undergoes three methylations by a histidine-alpha-N-methyltransferase (EC:2.1.1.44) to form N-alpha,N-alpha,N-alpha-trimethyl-L-histidine (also known as hercynine or histidine betaine).
52708	N-alpha,N-alpha,N-alpha-trimethyl-L-histidine metabolic process	P	The chemical reactions and pathways involving N-alpha,N-alpha,N-alpha-trimethyl-L-histidine, also known as histidine betaine or hercynine, a trimethylated derivative of histidine.
52709	N-alpha,N-alpha,N-alpha-trimethyl-L-histidine biosynthetic process	P	The chemical reactions and pathways resulting in the formation of N-alpha,N-alpha,N-alpha-trimethyl-L-histidine, also known as histidine betaine or hercynine, a trimethylated derivative of histidine.
52710	N-alpha,N-alpha,N-alpha-trimethyl-L-histidine catabolic process	P	The chemical reactions and pathways resulting in the breakdown of N-alpha,N-alpha,N-alpha-trimethyl-L-histidine, also known as histidine betaine or hercynine, a trimethylated derivative of histidine.
52711	ergothioneine biosynthesis from N-alpha,N-alpha,N-alpha-trimethyl-L-histidine	P	The pathway resulting in the formation of ergothioneine from N-alpha,N-alpha,N-alpha-trimethyl-L-histidine (also known as hercynine or histidine betaine).
52712	inositol phosphosphingolipid phospholipase activity	F	Catalysis of the reaction: inositol phosphosphingolipid + H2O = sphingolipid + phosphorylinositol.
52713	inositol phosphorylceramide phospholipase activity	F	Catalysis of the reaction: inositol phosphorylceramide + H2O = C26-phytoceramide + phosphorylinositol.
52714	mannosyl-inositol phosphorylceramide phospholipase activity	F	Catalysis of the reaction: mannosyl-inositol phosphorylceramide + H2O = C26-phytoceramide + mannosylphosphorylinositol.
52715	mannosyl-diinositol phosphorylceramide phospholipase activity	F	Catalysis of the reaction: mannosyl-diinositol phosphorylceramide + H2O = C26-phytoceramide + mannosyldiphosphorylinositol.
52716	hydroquinone:oxygen oxidoreductase activity	F	Catalysis of the reaction: 4 hydroquinone + O2 = 4 benzosemiquinone + 4 H2O.
52717	tRNA-specific adenosine-34 deaminase activity	F	Catalysis of the reaction: adenosine-34 + H2O = inosine-34 + NH3, in a tRNA-Ala molecule.
52718	tRNA-specific adenosine-34 deaminase complex	C	A protein complex that possesses tRNA-specific adenosine-34 deaminase activity. In eukaryotes the complex is a heterodimer; the subunits are known as Tad2p and Tad3p in yeasts and Adat2 and Adat3 in human.
52719	apurinic/apyrimidinic endoribonuclease activity	F	Catalysis of the hydrolysis of ester linkages immediately 5' to an apurinic/apyrimidinic (AP; also called abasic) site within a ribonucleic acid molecule by creating internal breaks, generating a single-strand break with 5'-ribose phosphate and 3'-hydroxyl ends.
52720	apurinic/apyrimidinic endodeoxyribonuclease activity	F	Catalysis of the hydrolysis of ester linkages immediately 5' to an apurinic/apyrimidinic (AP; also called abasic) site within a deoxyribonucleic acid molecule by creating internal breaks, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.
52721	regulation of apurinic/apyrimidinic endodeoxyribonuclease activity	P	Any process that modulates the frequency, rate or extent of apurinic/apyrimidinic (AP) endodeoxyribonuclease activity, the hydrolysis of ester linkages immediately 5' to an AP (also called abasic) site within a deoxyribonucleic acid molecule by creating internal breaks, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends.
52722	fatty acid in-chain hydroxylase activity	F	Catalysis of the reaction: fatty acid + O2 + 2 NADPH + H+ = fatty acid with in-chain hydroxy group + 2 NADP+ + H2O.
52723	inositol hexakisphosphate 1-kinase activity	F	Catalysis of the reaction: ATP + 1D-myo-inositol hexakisphosphate = ADP + 1-diphospho-1D-myo-inositol (2,3,4,5,6)pentakisphosphate.
52724	inositol hexakisphosphate 3-kinase activity	F	Catalysis of the reaction: ATP + 1D-myo-inositol hexakisphosphate = ADP + 3-diphospho-1D-myo-inositol (1,2,4,5,6)pentakisphosphate.
52725	inositol-1,3,4-trisphosphate 6-kinase activity	F	Catalysis of the reaction: 1D-myo-inositol 1,3,4-trisphosphate + ATP = 1D-myo-inositol 1,3,4,6-tetrakisphosphate + ADP + 2 H(+).
52726	inositol-1,3,4-trisphosphate 5-kinase activity	F	Catalysis of the reaction: 1D-myo-inositol 1,3,4-trisphosphate + ATP = 1D-myo-inositol 1,3,4,5-tetrakisphosphate + ADP + 2 H(+).
52727	capsanthin synthase activity	F	Catalysis of the reaction: antheraxanthin = capsanthin.
52728	capsorubin synthase activity	F	Catalysis of the reaction: violaxanthin = capsorubin.
52729	dimethylglycine N-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + N,N-dimethylglycine = S-adenosyl-L-homocysteine + betaine.
52730	sarcosine N-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + sarcosine = S-adenosyl-L-homocysteine + N,N-dimethylglycine.
52731	phosphocholine phosphatase activity	F	Catalysis of the reaction: choline phosphate + H2O = choline + phosphate.
52732	phosphoethanolamine phosphatase activity	F	Catalysis of the reaction: O-phosphoethanolamine + H2O = ethanolamine + phosphate.
52733	quinate 3-dehydrogenase (NADP+) activity	F	Catalysis of the reaction: quinate + NADP+ = 3-dehydroquinate + NADPH + H+.
52734	shikimate 3-dehydrogenase (NAD+) activity	F	Catalysis of the reaction: shikimate + NAD+ = 3-dehydroshikimate + NADH + H+.
52735	tRNA (cytosine-3-)-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing 3-methylcytosine.
52736	beta-glucanase activity	F	Catalysis of the hydrolysis of linkages in beta-D-glucans; beta-glucans are polysaccharides of D-glucose monomers linked by beta-glycosidic bonds.
52737	pyruvate dehydrogenase (quinone) activity	F	Catalysis of the reaction: a ubiquinone + H2O + pyruvate = a ubiquinol + acetate + CO2.
52738	oxidoreductase activity, acting on the aldehyde or oxo group of donors, with a quinone or similar compound as acceptor	F	Catalysis of an oxidation-reduction (redox) reaction in which an aldehyde or ketone (oxo) group acts as a hydrogen or electron donor and reduces a quinone or similar compound.
52739	phosphatidylserine 1-acylhydrolase activity	F	Catalysis of the reaction: phosphatidylserine + H2O = 2-acyl-sn-glycero-3-phosphoserine + fatty acid.
52740	1-acyl-2-lysophosphatidylserine acylhydrolase activity	F	Catalysis of the reaction: 1-acyl-2-lysophosphatidylserine + H2O = sn-glycerol-phosphoserine + a carboxylate.
52741	(R)-limonene 6-monooxygenase activity	F	Catalysis of the reaction: (4R)-limonene + H+ + NADPH + O2 = (1R,5S)-carveol + H2O + NADP+.
52742	phosphatidylinositol kinase activity	F	Catalysis of the reaction: ATP + a phosphatidylinositol = ADP + a phosphatidylinositol phosphate.
52743	inositol tetrakisphosphate phosphatase activity	F	Catalysis of the reaction: myo-inositol tetrakisphosphate + H2O = myo-inositol trisphosphate + phosphate.
52744	phosphatidylinositol monophosphate phosphatase activity	F	Catalysis of the reaction: phosphatidylinositol monophosphate + H2O = phosphatidylinositol + phosphate.
52745	inositol phosphate phosphatase activity	F	Catalysis of the reaction: inositol phosphate(n) + H2O = inositol phosphate(n-1) + phosphate. This reaction is the removal of a phosphate group from an inositol phosphate.
52746	inositol phosphorylation	P	The process of introducing one or more phosphate groups into inositol. Inositol is the cyclic alcohol 1,2,3,4,5,6-cyclohexanehexol, which is widely distributed in nature and acts as a growth factor in animals and microorganisms.
52747	sinapyl alcohol dehydrogenase activity	F	Catalysis of the reaction: sinapaldehyde + NADPH + H+ = sinapyl-alcohol + NADP+.
52748	baicalin beta-D-glucuronidase activity	F	Catalysis of the reaction: baicalin + H2O = baicalein + D-glucuronate.
52749	glucose-6-phosphate dehydrogenase (coenzyme F420) activity	F	Catalysis of the reaction: beta-D-glucose 6-phosphate + coenzyme F420 + H+ = 6-O-phosphono-D-glucono-1,5-lactone + reduced coenzyme F420.
52750	reactive-black-5:hydrogen-peroxide oxidoreductase activity	F	Catalysis of the reaction: reactive black 5 + hydrogen peroxide = oxidized reactive black 5 + 2 H2O.
52751	GDP-mannose hydrolase activity	F	Catalysis of the reaction: GDP-mannose + H2O = GMP + mannose-1-phosphate.
52752	reduced coenzyme F420:heterodisulfide oxidoreductase activity	F	Catalysis of the reaction: reduced coenzyme F420 + CoB-S-S-CoM = coenzyme F420 + CoM-SH + CoB-SH.
52753	propan-2-ol:coenzyme F420 oxidoreductase activity	F	Catalysis of the reaction: propan-2-ol + coenzyme F420 = acetone + reduced coenzyme F420.
52754	GTP:coenzyme F420 guanyltransferase activity	F	Catalysis of the reaction: GTP + factor gamma-F420-2 + H+ = coenzyme F390-G + diphosphate.
52755	reduced coenzyme F420:quinone oxidoreductase activity	F	Catalysis of the reaction: reduced coenzyme F420 + 2,3-dimethyl-1,4-naphthoquinone = coenzyme F420 + reduced 2,3-dimethyl-1,4-naphthoquinone. Reduced 2,3-dimethyl-1,4-naphthoquinone is also known as 2,3-dimethyl-1,4-hydronaphthoquinone.
52756	chitobiose phosphorylase activity	F	Catalysis of the reaction: chitobiose + phosphate = N-acetyl-D-glucosamine + N-acetyl-alpha-D-glucosamine 1-phosphate. This reaction is the phosphorolysis of chitobiose, (GlcNAc)2, a dimer of beta-(1->4) linked glucosamine units.
52757	chondroitin hydrolase activity	F	Catalysis of the hydrolysis of hexosaminic linkages in chondroitin, a linear polymer structure composed of the repeating disaccharide unit [->4)-D-glucuronic acid-(1->3)-N-acetyl-D-galactosamine-(1-], also written as [->4GlcUA1->3GalNAc1-].
52758	coenzyme F420-dependent 2,4,6-trinitrophenol reductase activity	F	Catalysis of the reaction: 2,4,6-trinitrophenol + H- = 2,4,6-trinitrophenol hydride Meisenheimer complex. Coenzyme F420 supplies the hydride (H-) in the reaction.
52759	coenzyme F420-dependent 2,4,6-trinitrophenol hydride reductase activity	F	Catalysis of the reaction: trinitrophenol hydride Meisenheimer complex + H- = trinitrophenol dihydride Meisenheimer complex (aci form). Coenzyme F420 supplies the hydride (H-) in the reaction.
52760	coenzyme F420-dependent 2,4-dinitrophenol reductase activity	F	Catalysis of the reaction: 2,4-dinitrophenol + H- = 2,4-dinitrophenol hydride Meisenheimer complex. Coenzyme F420 supplies the hydride (H-) in the reaction.
52761	exo-1,4-beta-D-glucosaminidase activity	F	Catalysis of the reaction: [beta-(1->4)-D-glucosamine]n-[N-acetyl-D-glucosamine]m = D-glucosamine + [beta-(1->4)-D-glucosamine](n-1)-[N-acetyl-D-glucosamine]m. This reaction is the hydrolysis of chitosan or chitosan oligosaccharides to remove a D-glucosamine residue from the non-reducing termini; chitosan is a linear polysaccharide composed of randomly distributed beta-(1->4)-linked D-glucosamine and N-acetyl-D-glucosamine units.
52762	gellan lyase activity	F	Catalysis of the reaction: gellan = n beta-D-4-deoxy-delta4,5-GlcAp-(1->4)-beta-D-Glcp-(1->4)-alpha-L-Rhap-(1->3)-beta-D-Glcp. This reaction is the eliminative cleavage of beta-D-glucopyranosyl-(1->4)-beta-D-glucopyranosyluronate bonds of gellan backbone, releasing tetrasaccharides containing a 4-deoxy-4,5-unsaturated D-glucopyranosyluronic acid at the non-reducing end; in the product, the abbreviations are D-glucose (Glc), D-glucuronic acid (GlcA), and L-rhamnose (Rha).
52763	ulvan lyase activity	F	Catalysis of the cleavage of a carbon-oxygen bond in ulvan, a carbohydrate composed of a repeating structure of [->4)-beta-D-GlcA-(1,4)-alpha-L-Rha 3S-(1->4)-alpha-L-IdoA-(1->4)-alpha-L-Rha 3S-(1-]n. Continued digest of ulvan with an enzyme that can catalyze this reaction results in ulvanobiouronic acid A 3-sulfate [->4)-beta-D-GlcpA-(1->4)-alpha-L-Rhap 3-sulfate-(1-]n with 4-deoxy-L-threo-hex-4-enopyranosiduronic acid at the non-reducing end.
52764	exo-oligoalginate lyase activity	F	Catalysis of the cleavage of glycosidic bonds through a beta-elimination reaction on alginate, a linear polysaccharide consisting of guluronate (G) and mannuronate (M) as the monomer constituents. An oligoalginate is a linear polymer of two, three or four units of (1->4)-alpha-L-guluronic acid and beta-D-mannuronic acid, releasing monosaccharides with 4-deoxy-alpha-L-erythro-hex-4-enopyranuronosyl groups at their ends.
52765	reduced coenzyme F420 oxidase activity	F	Catalysis of the reaction: 2 reduced coenzyme F420 + O2 = 2 coenzyme F420 + 2 H2O.
52766	mannoside alpha-1,4-mannosidase activity	F	Catalysis of the hydrolysis of the alpha-(1->4) linkage of the terminal, non-reducing alpha-D-mannose residues in alpha-D-mannosides.
52767	mannosyl-oligosaccharide 1,6-alpha-mannosidase activity	F	Catalysis of the hydrolysis of the alpha-(1->6) bonds of alpha-D-mannose residues in mannosyl-oligosaccharide.
52768	mannosyl-oligosaccharide 1,3-alpha-mannosidase activity	F	Catalysis of the hydrolysis of the alpha-(1->3) bonds of alpha-D-mannose residues in mannosyl-oligosaccharide.
52769	beta-6-sulfate-N-acetylglucosaminidase activity	F	Catalysis of the glycosidic cleavage of the terminal 2-acetamido-2-deoxy-beta-D-glucopyranoside 6-sulfate (6-SO3-GlcNAc) residue from sulfomucin, a sulfated mucin derivative.
52770	coenzyme F390-A hydrolase activity	F	Catalysis of the reaction: coenzyme F390-A = AMP + coenzyme F420.
52771	coenzyme F390-G hydrolase activity	F	Catalysis of the reaction: coenzyme F390-G = GMP + coenzyme F420.
52772	brefeldin A esterase activity	F	Catalysis of the hydrolysis of brefeldin A to produce brefeldin A acid. Brefeldin A is also known as gamma,4-dihydroxy-2-(6-hydroxy-1-heptenyl)-4-cyclopentanecrotonic acid lambda-lactone.
52773	diacetylchitobiose deacetylase activity	F	Catalysis of the reaction: N,N'-diacetylchitobiose (GlcNac2) + H2O = acetate + 2-acetamido-4-O-(2-amino-2-deoxy-beta-D-glucopyranosyl)-2-deoxy-D-glucose (GlcN-GlcNAc).
52774	glucosyl-N-acetylglucosamine glucosaminidase activity	F	Catalysis of the reaction: glucosyl-N-acetylglucosamine + H2O = glucosamine + N-acetylglucosamine.
52775	endo-1,3-alpha-L-rhamnosidase activity	F	Catalysis of the reaction: R1-L-rhamnose-(1->3)-alpha-L-rhamnose-R2 + H2O = R1-L-rhamnose + L-rhamnose-R2. This reaction is the hydrolysis of an alpha-(1->3) linkage between two rhamnose residues in a polysaccharide chain.
52776	diacetylchitobiose catabolic process to glucosamine and acetate	P	The pathway resulting in the breakdown of diacetylchitobiose into simpler products, including glucosamine and glucosamine. The catabolism proceeds by the deacetylation of diacetylchitobiose, producing acetate and GlcN-GlcNAc; the latter is cleaved to produce glucosamine (GlcN) and N-acetylglucosamine (GlcNAc). The N-acetylglucosamine (GlcNAc) is then deacetylated to produce glucosamine (GlcN) and acetate.
52777	diacetylchitobiose catabolic process	P	The chemical reactions and pathways resulting in the breakdown of diacetylchitobiose into simpler products.
52778	diacetylchitobiose metabolic process	P	The chemical reactions and pathways involving diacetylchitobiose, the N,N'-diacetylated derivative of chitobiose.
52779	amino disaccharide metabolic process	P	The chemical reactions and pathways involving any amino disaccharide, a disaccharide having one or more substituted or unsubstituted amino groups in place of hydroxy groups at unspecified positions.
52780	chitobiose metabolic process	P	The chemical reactions and pathways involving chitobioses, a family of compounds derived from chitin and based on the structure of D-glucosaminyl-(1->4)-D-glucosamine.
52781	chitobiose catabolic process	P	The chemical reactions and pathways resulting in the breakdown of any chitobiose, a family of compounds derived from chitin and based on the structure of D-glucosaminyl-(1->4)-D-glucosamine.
52782	amino disaccharide catabolic process	P	The chemical reactions and pathways resulting in the breakdown of any amino disaccharide, a disaccharide having one or more substituted or unsubstituted amino groups in place of hydroxy groups at unspecified positions.
52783	reuteran metabolic process	P	The chemical reactions and pathways involving reuteran, a soluble glucan polymer with mainly alpha-(1->4) glycosidic linkages and significant amounts of alpha-(1->6) and alpha-(1->4,6) glucosidic linkages.
52784	reuteran biosynthetic process	P	The chemical reactions and pathways resulting in the formation of reuteran, a soluble glucan polymer with mainly alpha-(1->4) glycosidic linkages and significant amounts of alpha-(1->6) and alpha-(1->4,6) glucosidic linkages.
52785	cellulose catabolism by endo-processive cellulases	P	The breakdown into simpler components of cellulose. Catabolism is initiated by endohydrolytic attacks on the cellulose chain, and the resulting pieces are further degraded by cellulase enzymes to produce smaller and smaller fragments.
52786	alpha-linked polysaccharide catabolism to maltotriose	P	The breakdown of large alpha-linked polysaccharides by hydrolysis of (1->4)-alpha-D-glucosidic linkages to yield maltotriose.
52787	alpha-linked polysaccharide catabolism to maltopentaose	P	The breakdown of large alpha-linked polysaccharides by hydrolysis of (1->4)-alpha-D-glucosidic linkages to yield maltopentaose.
52788	d-4,5 unsaturated beta-glucuronyl hydrolase activity	F	Catalysis of the hydrolysis of the glycosidic bond in an unsaturated saccharide between the unsaturated glucuronyl residue at the nonreducing terminus and the saccharide linked to the residue.
52789	mannan 1,3-beta-mannosidase activity	F	Catalysis of the hydrolysis of (1->3)-beta-D-mannosidic linkages in mannans, releasing mannose.
52790	chitooligosaccharide deacetylase activity	F	Catalysis of the reaction: chitooligosaccharide with N-acetylglucosamine at nonreducing terminal + H2O = chitooligosaccharide with glucosamine at nonreducing terminal + acetate. This reaction is the deacetylation of a chitooligosaccharide at the nonreducing N-acetylglucosamine residue; chitooligosaccharide are composed of (1->4)-linked D-glucosamine (GlcN) and N-acetyl-D-glucosamine (GlcNAc) in varying proportions.
52791	3-deoxy-D-glycero-D-galacto-2-nonulosonic acid hydrolase activity	F	Catalysis of the reaction: (2-keto-3-deoxynononic acid)n + H2O = (2-keto-3-deoxynononic acid)n-1 + 2-keto-3-deoxynononic acid. This reaction is the hydrolysis of a 2-keto-3-deoxynononic acid residue from a poly-2-keto-3-deoxynononic acid chain.
52792	endo-xylogalacturonan hydrolase activity	F	Catalysis of the endohydrolysis of xylogalacturonate by cleavage of the alpha-(1,4)-linkage. Xylogalacturonate (XGA) is composed of a chain of alpha-(1,4)-linked D-galacturonic acid residues with beta-D-xylose substituted at the O3 position.
52793	pectin acetylesterase activity	F	Catalysis of the reaction: pectin + H2O = pectate + acetate. This reaction is the hydrolysis of acetyl esters of pectin, producing pectate, partially esterified pectin.
52794	exo-alpha-(2->3)-sialidase activity	F	Catalysis of the hydrolysis of alpha-(2->3)-glycosidic linkages of terminal sialic residues in substrates.
52795	exo-alpha-(2->6)-sialidase activity	F	Catalysis of the hydrolysis of alpha-(2->6)-glycosidic linkages of terminal sialic residues in substrates.
52796	exo-alpha-(2->8)-sialidase activity	F	Catalysis of the hydrolysis of alpha-(2->8)-glycosidic linkages of terminal sialic residues in substrates.
52797	4-O-methyl-glucuronoyl methylesterase activity	F	Catalysis of the reaction: [X]-4-O-methyl-D-glucuronic acid + H2O = [X]-OH + methyl-D-glucuronic acid. This reaction is the hydrolysis of the ester linkage between 4-O-methyl-D-glucuronic acid (MeGlcA) and an alcohol (-OH) group attached to a molecule, denoted here as [X].
52798	beta-galactoside alpha-2,3-sialyltransferase activity	F	Catalysis of the transfer of sialyl residues alpha-2,3-linked to a beta galactosyl residue on the donor to form an alpha-2,3 linkage to a terminal beta galactosyl residue on the acceptor.
52799	coenzyme F420-dependent bicyclic nitroimidazole catabolic process	P	The breakdown of a bicyclic nitroimidazole into simpler components in a process that requires coenzyme F420 and produces reactive nitrogen species. Hydride, from reduced coenzyme F420, is added to the bicyclic nitroimidazole, resulting in unstable substances that break down to form three stable products. The elimination of nitrous acid produces the corresponding des-nitroimidazole; hydrolysis produces a related compound; and further reduction creates an aromatic hydroxylamine metabolite that degrades further. These reactions release hyponitrous acid and nitrous acid, which is unstable and disproportionates into nitric oxide (NO) and other reactive nitrogen intermediates.
52800	bicyclic nitroimidazole catabolic process	P	The chemical reactions and pathways resulting in the breakdown of a bicyclic nitroimidazole.
52801	bicyclic nitroimidazole metabolic process	P	The chemical reactions and pathways involving bicyclic nitroimidazoles, imidazole derivatives with two rings and a nitro group attached to one ring.
52802	nitroimidazole metabolic process	P	The chemical reactions and pathways involving nitroimidazoles, imidazole derivatives with a nitro group attached to one ring.
52803	imidazole-containing compound metabolic process	P	The chemical reactions and pathways involving imidazoles, five-membered organic heterocycle containing two nitrogen atoms at positions 1 and 3, or any of its derivatives; compounds containing an imidazole skeleton.
52804	nitroimidazole catabolic process	P	The chemical reactions and pathways resulting in the breakdown of nitroimidazoles, imidazole derivatives with a nitro group attached to one ring.
52805	imidazole-containing compound catabolic process	P	The chemical reactions and pathways resulting in the breakdown of imidazoles, five-membered organic heterocycle containing two nitrogen atoms at positions 1 and 3, or any of its derivatives; compounds containing an imidazole skeleton.
52806	sulfite reductase (coenzyme F420) activity	F	Catalysis of the reaction: sulfite + 3 1,5-dihydrocoenzyme F420 = hydrogen sulfide + 3 H2O + 3 coenzyme F420. 1,5-dihydrocoenzyme F420 is also known as reduced coenzyme F420.
52807	aflatoxin reductase (coenzyme F420) activity	F	Catalysis of the reaction: aflatoxin + 1,5-dihydrocoenzyme F420 = aflatoxin with reduced furanocoumarin moiety + coenzyme F420. 1,5-dihydrocoenzyme F420 is also known as reduced coenzyme F420.
52808	reduced coenzyme F420:NADP+ oxidoreductase activity	F	Catalysis of the reaction: NADP+ + 1,5-dihydrocoenzyme F420 = NADPH + H+ + coenzyme F420. 1,5-dihydrocoenzyme F420 is also known as reduced coenzyme F420.
52809	acharan sulfate lyase activity	F	Catalysis of the cleavage of a carbon-oxygen bond in acharan sulfate, a glycosaminoglycan with a uniformly repeating disaccharide structure of alpha-D-N-acetylglucosaminyl-2-O-sulfo-alpha-L-iduronic acid.
52810	1-phosphatidylinositol-5-kinase activity	F	Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol + ATP = a 1-phosphatidyl-1D-myo-inositol 5-phosphate + ADP + 2 H(+).
52811	1-phosphatidylinositol-3-phosphate 4-kinase activity	F	Catalysis of the reaction: a 1-phosphatidyl-1D-myo-inositol 4-phosphate + ATP = a 1-phosphatidyl-1D-myo-inositol 3,4-bisphosphate + ADP + 2 H(+).
52812	phosphatidylinositol-3,4-bisphosphate 5-kinase activity	F	Catalysis of the reaction: 1-phosphatidyl-1D-myo-inositol 3,4-bisphosphate + ATP = a 1-phosphatidyl-1D-myo-inositol 3,4,5-trisphosphate + ADP + 2 H(+).
52813	phosphatidylinositol bisphosphate kinase activity	F	Catalysis of the reaction: ATP + a phosphatidylinositol bisphosphate = ADP + a phosphatidylinositol trisphosphate.
52814	medium-chain-aldehyde dehydrogenase activity	F	Catalysis of the reaction: a medium-chain aldehyde + NAD+ = a medium-chain carboxylate + NADH + H+. Medium-chain aldehydes have a chain length of between 8 and 12 carbons.
52815	medium-chain acyl-CoA hydrolase activity	F	Catalysis of the reaction: H2O + a medium-chain acyl-CoA = a medium-chain carboxylate + CoA. A medium chain is a chain of between eight and twelve carbons in length.
52816	long-chain acyl-CoA hydrolase activity	F	Catalysis of the reaction: H2O + a long-chain acyl-CoA = a long-chain carboxylate + CoA. A long chain is a chain of greater than 12 carbons in length.
52817	very long chain acyl-CoA hydrolase activity	F	Catalysis of the reaction: H2O + a very long chain acyl-CoA = a very long chain carboxylate + CoA. A very long chain has chain length greater than C18.
52818	heteroglycan 3-alpha-mannosyltransferase activity	F	Catalysis of the reaction: heteroglycan + GDP-mannose = (1->3)-alpha-D-mannosylheteroglycan + GDP.
52819	heteroglycan 2-alpha-mannosyltransferase activity	F	Catalysis of the reaction: heteroglycan + GDP-mannose = (1->2)-alpha-D-mannosylheteroglycan + GDP.
52820	DNA-1,N6-ethenoadenine N-glycosylase activity	F	Catalysis of the reaction: DNA with 1-N6-ethenoadenine + H2O = DNA with abasic site + 1-N6-ethenoadenine. This reaction is the removal of 1,N6-ethenoadenine by cleaving the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar.
52821	DNA-7-methyladenine glycosylase activity	F	Catalysis of the reaction: DNA containing 7-methyladenine + H2O = DNA with abasic site + 7-methyladenine. This reaction is the hydrolysis of DNA by cleavage of the N-C1' glycosidic bond between the damaged DNA 7-methyladenine and the deoxyribose sugar to remove the 7-methyladenine, leaving an abasic site.
52822	DNA-3-methylguanine glycosylase activity	F	Catalysis of the reaction: DNA containing 3-methylguanine + H2O = DNA with abasic site + 3-methylguanine. This reaction is the hydrolysis of DNA by cleavage of the N-C1' glycosidic bond between the damaged DNA 3-methylguanine and the deoxyribose sugar to remove the 3-methylguanine, leaving an abasic site.
52823	2-hydroxy-6-oxonona-2,4,7-trienedioate hydrolase activity	F	Catalysis of the reaction: (2E,4Z,7E)-2-hydroxy-6-oxonona-2,4,7-trienedioate + H2O = (2E)-2-hydroxypenta-2,4-dienoate + fumarate + H+.
52824	dolichyl-pyrophosphate Man7GlcNAc2 alpha-1,6-mannosyltransferase activity	F	Catalysis of the addition of mannose to dolichyl-pyrophosphate Man7GlcNAc2 (also written as Man7GlcNAc2-PP-Dol) in alpha-(1->6) linkage, producing Man8GlcNAc2-PP-Dol.
52825	inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity	F	Catalysis of the reaction: inositol-1,3,4,5,6-pentakisphosphate + H2O = inositol-3,4,5,6-tetrakisphosphate + phosphate.
52826	inositol hexakisphosphate 2-phosphatase activity	F	Catalysis of the reaction: myo-inositol hexakisphosphate + H2O = myo-inositol 1,3,4,5,6-pentakisphosphate + phosphate.
52827	inositol pentakisphosphate phosphatase activity	F	Catalysis of the reaction: myo-inositol pentakisphosphate + H2O = myo-inositol tetrakisphosphate + phosphate.
52828	inositol-3,4-bisphosphate 4-phosphatase activity	F	Catalysis of the reaction: 1D-myo-inositol 3,4-bisphosphate + H2O = 1D-myo-inositol 3-phosphate + phosphate.
52829	inositol-1,3,4-trisphosphate 1-phosphatase activity	F	Catalysis of the reaction: D-myo-inositol 1,3,4-trisphosphate + H2O = myo-inositol 3,4-bisphosphate + phosphate.
52830	inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity	F	Catalysis of the reaction: inositol-1,3,4,6-tetrakisphosphate + H2O = inositol-1,3,4-trisphosphate + phosphate.
52831	inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity	F	Catalysis of the reaction: inositol-1,3,4,6-tetrakisphosphate + H2O = inositol-3,4,6-trisphosphate + phosphate.
52832	inositol monophosphate 3-phosphatase activity	F	Catalysis of the reaction: myo-inositol 3-phosphate + H2O = myo-inositol + phosphate.
52833	inositol monophosphate 4-phosphatase activity	F	Catalysis of the reaction: myo-inositol 4-phosphate + H2O = myo-inositol + phosphate.
52834	inositol monophosphate phosphatase activity	F	Catalysis of the reaction: myo-inositol phosphate + H2O = myo-inositol + phosphate.
52835	inositol-3,4,6-trisphosphate 1-kinase activity	F	Catalysis of the reaction: 1D-myo-inositol 3,4,6-trisphosphate + ATP = 1D-myo-inositol 1,3,4,6-tetrakisphosphate + ADP + 2 H(+).
52836	inositol 5-diphosphate pentakisphosphate 5-kinase activity	F	Catalysis of the reaction: ATP + inositol 5-diphosphate pentakisphosphate = ADP + inositol 5-triphosphate pentakisphosphate.
52837	thiazole biosynthetic process	P	The chemical reactions and pathways resulting in the formation of a thiazole, a five-membered heterocyclic ring structure containing a sulfur in the 1-position and a nitrogen in the 3-position.
52838	thiazole metabolic process	P	The chemical reactions and pathways involving thiazole, a five-membered heterocyclic ring structure containing a sulfur in the 1-position and a nitrogen in the 3-position.
52839	inositol diphosphate tetrakisphosphate kinase activity	F	Catalysis of the reaction: Catalysis of the reaction: ATP + inositol diphosphate tetrakisphosphate = ADP + inositol bisdiphosphate trisphosphate.
52840	inositol diphosphate tetrakisphosphate diphosphatase activity	F	Catalysis of the reaction: inositol diphosphate tetrakisphosphate + H2O = inositol 1,3,4,5,6-pentakisphosphate + phosphate.
52841	inositol bisdiphosphate tetrakisphosphate diphosphatase activity	F	Catalysis of the reaction: inositol bisdiphosphate tetrakisphosphate + H2O = inositol diphosphate pentakisphosphate + phosphate.
52842	inositol diphosphate pentakisphosphate diphosphatase activity	F	Catalysis of the reaction: inositol diphosphate pentakisphosphate + H2O = inositol hexakisphosphate + phosphate.
52843	inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity	F	Catalysis of the reaction: inositol 1-diphosphate 2,3,4,5,6-pentakisphosphate + H2O = inositol 1,2,3,4,5,6-hexakisphosphate + phosphate + 2 H+.
52844	inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity	F	Catalysis of the reaction: inositol 3-diphosphate 1,2,4,5,6-pentakisphosphate + H2O = inositol 1,2,3,4,5,6-hexakisphosphate + phosphate + 2 H+.
52845	inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity	F	Catalysis of the reaction: inositol 5-diphosphate 1,2,3,4,6-pentakisphosphate + H2O = inositol 1,2,3,4,5,6-hexakisphosphate + phosphate + 2 H+.
52846	inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity	F	Catalysis of the reaction: 1,5-bisdiphosphoinositol-1D-myo-inositol 2,3,4,6-tetrakisphosphate + H2O = 1-diphospho-1D-myo-inositol 1,2,3,4,6-pentakisphosphate + phosphate + H+.
52847	inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity	F	Catalysis of the reaction: 1,5-bisdiphosphoinositol-1D-myo-inositol 2,3,4,6-tetrakisphosphate + H2O = 1-diphospho-1D-myo-inositol 2,3,4,5,6-pentakisphosphate + phosphate + H+.
52848	inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity	F	Catalysis of the reaction: 3,5-bisdiphosphoinositol-1D-myo-inositol 2,3,4,6-tetrakisphosphate + H2O = 3-diphospho-1D-myo-inositol 1,2,4,5,6-pentakisphosphate + phosphate + H+.
52849	NADPH-dependent curcumin reductase activity	F	Catalysis of the reaction: curcumin + NADPH + H+ = dihydrocurcumin + NADP+.
52850	NADPH-dependent dihydrocurcumin reductase activity	F	Catalysis of the reaction: dihydrocurcumin + NADPH+ + H+ = tetrahydrocurcumin + NADP+.
52851	ferric-chelate reductase (NADPH) activity	F	Catalysis of the reaction: 2 Fe3+ + NADPH = 2 Fe2+ + H+ + NADP+.
52852	very-long-chain-(S)-2-hydroxy-acid oxidase activity	F	Catalysis of the reaction: very-long-chain (S)-2-hydroxy-acid + O2 = very-long-chain 2-oxo acid + hydrogen peroxide. Very long chain refers to a chain length of greater than 18 carbons.
52853	long-chain-(S)-2-hydroxy-long-chain-acid oxidase activity	F	Catalysis of the reaction: long-chain-(S)-2-hydroxy-acid + O2 = long-chain-2-oxo acid + hydrogen peroxide. Long chain refers to a chain length of 14 to 18 carbons.
52854	medium-chain-(S)-2-hydroxy-acid oxidase activity	F	Catalysis of the reaction: medium-chain-(S)-2-hydroxy-acid + O2 = medium-chain-2-oxo acid + hydrogen peroxide. Medium chain refers to a chain length of between 8 and 12 carbons.
52855	ADP-dependent NAD(P)H-hydrate dehydratase activity	F	Catalysis of the reaction: (6S)-6beta-hydroxy-1,4,5,6-tetrahydronicotinamide adenine dinucleotide + ADP = AMP + 3 H(+) + NADH + phosphate.
52856	NADHX epimerase activity	F	Catalysis of the reaction: (R)-NADHX = (S)-NADHX.
52857	NADPHX epimerase activity	F	Catalysis of the reaction: (R)-NADPHX = (S)-NADPHX.
52858	peptidyl-lysine acetyltransferase activity	F	Catalysis of the reaction: acetyl phosphate + peptidyl-L-lysine = phosphate + peptidyl-N6-acetyl-L-lysine.
52859	glucan endo-1,4-beta-glucosidase activity	F	Catalysis of the random hydrolysis of (1->4) linkages in (1->4)-beta-D-glucans.
52860	2'-deoxymugineic-acid 3-dioxygenase activity	F	Catalysis of the reaction: 2'-deoxymugineic acid + 2-oxoglutarate + O2 = 3-epihydroxy-2'-deoxymugineic acid + succinate + CO2.
52861	glucan endo-1,3-beta-glucanase activity, C-3 substituted reducing group	F	Catalysis of the endohydrolysis of (1->3)-linkages in beta-D-glucans when the glucose residue whose reducing group is involved in the linkage to be hydrolysed is itself substituted at C-3.
52862	glucan endo-1,4-beta-glucanase activity, C-3 substituted reducing group	F	Catalysis of the endohydrolysis of (1->4)-linkages in beta-D-glucans when the glucose residue whose reducing group is involved in the linkage to be hydrolysed is itself substituted at C-3.
52863	1-deoxy-D-xylulose 5-phosphate metabolic process	P	The chemical reactions and pathways involving 1-deoxy-D-xylulose 5-phosphate, the 5-phospho derivative of 1-deoxy-D-xylulose. 1-deoxy-D-xylulose 5-phosphate is an intermediate in the non-mevalonate pathway and a common precursor for isoprenoid, thiamin, and pyridoxol biosynthesis.
52864	1-deoxy-D-xylulose 5-phosphate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of 1-deoxy-D-xylulose 5-phosphate, the 5-phospho derivative of 1-deoxy-D-xylulose. 1-deoxy-D-xylulose 5-phosphate is an intermediate in the non-mevalonate pathway and a common precursor for isoprenoid, thiamin, and pyridoxol biosynthesis.
52865	1-deoxy-D-xylulose 5-phosphate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of 1-deoxy-D-xylulose 5-phosphate, the 5-phospho derivative of 1-deoxy-D-xylulose. 1-deoxy-D-xylulose 5-phosphate is an intermediate in the non-mevalonate pathway and a common precursor for isoprenoid, thiamin, and pyridoxol biosynthesis.
52866	phosphatidylinositol phosphate phosphatase activity	F	Catalysis of the reaction: phosphatidylinositol phosphate(n) + H2O = phosphatidylinositol phosphate(n-1) + phosphate. This reaction is the removal of a phosphate group from a phosphatidylinositol phosphate.
52867	phosphatidylinositol-1,4,5-trisphosphate 5-phosphatase activity	F	Catalysis of the reaction: phosphatidyl-1D-myo-inositol 1,4,5-trisphosphate + H(2)O = 1-phosphatidyl-1D-myo-inositol 1,4-bisphosphate + phosphate.
52868	protein-lysine lysyltransferase activity	F	Catalysis of the reaction: protein-lysine + protein-lysine = protein N6-(lysyl)-L-lysine + protein. This reaction is the addition of lysine group from one protein to a lysine residue in a second protein, producing N6-(lysyl)-L-lysine.
52869	arachidonic acid omega-hydroxylase activity	F	Catalysis of the reaction: arachidonic acid + O2 + NADPH + H+ = 20-HETE + NADP+ + H2O. Arachidonic acid is also known as (5Z,8Z,11Z,14Z)-icosatetraenoic acid, and 20-HETE is also known as (5Z,8Z,11Z,14Z)-20-hydroxyicosa-5,8,11,14-tetraenoic acid.
52870	tocopherol omega-hydroxylase activity	F	Catalysis of the reaction: tocopherol + O2 + NADPH + H+ = 13'-hydroxy-tocopherol + NADP+ + H2O.
52871	alpha-tocopherol omega-hydroxylase activity	F	Catalysis of the reaction: alpha-tocopherol + O2 + NADPH + H+ = 13'-hydroxy-alpha-tocopherol + NADP+ + H2O.
52872	tocotrienol omega-hydroxylase activity	F	Catalysis of the reaction: tocotrienol + O2 + NADPH + H+ = 13'-hydroxy-tocotrienol + NADP+ + H2O.
52873	FMN reductase (NADPH) activity	F	Catalysis of the reaction: FMNH2 + NADP+ = FMN + NADPH + 2 H+.
52874	FMN reductase (NADH) activity	F	Catalysis of the reaction: FMNH2 + NAD+ = FMN + NADH + 2 H+.
52875	riboflavin reductase (NADH) activity	F	Catalysis of the reaction: reduced riboflavin + NAD+ = riboflavin + NADH + 2 H+.
52876	methylamine dehydrogenase (amicyanin) activity	F	Catalysis of the reaction: methylamine + H2O + amicyanin = formaldehyde + ammonia + reduced amicyanin.
52877	oxidoreductase activity, acting on the CH-NH2 group of donors, with a copper protein as acceptor	F	Catalysis of an oxidation-reduction (redox) reaction in which a CH-NH2 group acts as a hydrogen or electron donor and a copper protein is the acceptor.
52878	linoleate 8R-lipoxygenase activity	F	Catalysis of the reaction: O(2) + linoleate = (8R,9Z,12Z)-8-hydroperoxyoctadeca-9,12-dienoate.
52879	9,12-octadecadienoate 8-hydroperoxide 8S-isomerase activity	F	Catalysis of the reaction: (8R,9Z,12Z)-8-hydroperoxyoctadeca-9,12-dienoate = (7S,8S,9Z,12Z)-7,8-dihydroxyoctadeca-9,12-dienoate.
52880	oxidoreductase activity, acting on diphenols and related substances as donors, with copper protein as acceptor	F	Catalysis of an oxidation-reduction (redox) reaction in which a diphenol, or related compound, acts as a hydrogen or electron donor and reduces a copper protein.
52881	4-hydroxyphenylacetate 3-monooxygenase activity	F	Catalysis of the reaction: (4-hydroxyphenyl)acetate + FADH(2) + O(2) = 3,4-dihydroxyphenylacetate + FAD + H(+) + H(2)O.
52882	oxidoreductase activity, acting on phosphorus or arsenic in donors, with a copper protein as acceptor	F	Catalysis of an oxidation-reduction (redox) reaction in which a phosphorus- or arsenic-containing group acts as a hydrogen or electron donor and reduces a copper protein.
52883	tyrosine ammonia-lyase activity	F	Catalysis of the reaction: L-tyrosine = NH(4)(+) + trans-4-coumarate.
52884	all-trans-retinyl-palmitate hydrolase, 11-cis retinol forming activity	F	Catalysis of the reaction: H(2)O + all-trans-retinyl palmitate = 11-cis-retinol + H(+) + palmitate.
52885	all-trans-retinyl-ester hydrolase, 11-cis retinol forming activity	F	Catalysis of the reaction: H(2)O + all-trans-retinyl ester = 11-cis-retinol + fatty acid.
52886	9,9'-dicis-carotene:quinone oxidoreductase activity	F	Catalysis of the reaction: 9,9'-di-cis-zeta-carotene + a quinone = 7,9,9'-tri-cis-neurosporene + a quinol.
52887	7,9,9'-tricis-neurosporene:quinone oxidoreductase activity	F	Catalysis of the reaction: 7,9,9'-tri-cis-neurosporene + a quinone = 7,9,7',9'-tetra-cis-lycopene + a quinol.
52889	9,9'-di-cis-zeta-carotene desaturation to 7,9,7',9'-tetra-cis-lycopene	P	The series of reactions in which 9,9'-di-cis-zeta-carotene is desaturated to 7,9,9'-tri-cis-neurosporene, and then 7,9,7',9'-tetra-cis-lycopene. The overall reaction for this process is: 9,9'-di-cis-zeta-carotene + 2 quinone = 2 quinol + 7,9,7',9'-tetra-cis-lycopene.
52890	oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor	F	Catalysis of an oxidation-reduction (redox) reaction in which a CH-CH group acts as a hydrogen or electron donor and reduces a flavin.
52891	aliphatic (S)-hydroxynitrile lyase activity	F	Catalysis of the reaction: an aliphatic (S)-hydroxynitrile = an aliphatic aldehyde or ketone + cyanide.
52892	aromatic (S)-hydroxynitrile lyase activity	F	Catalysis of the reaction: an aromatic (S)-hydroxynitrile = an aromatic aldehyde + cyanide.
52893	N1-acetylspermine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity	F	Catalysis of the reaction: N1-acetylspermine + oxygen + H2O = N-(3-acetamidopropyl)-4-aminobutanal + propane-1,3-diamine + hydrogen peroxide.
52894	norspermine:oxygen oxidoreductase activity	F	Catalysis of the reaction: norspermine + oxygen + H2O = norspermidine + 3-aminopropanal + hydrogen peroxide.
52895	N1-acetylspermine:oxygen oxidoreductase (N1-acetylspermidine-forming) activity	F	Catalysis of the reaction: N1-acetylspermine + oxygen + H2O = N1-acetylspermidine + 3-aminopropanal + hydrogen peroxide.
52896	spermidine oxidase (propane-1,3-diamine-forming) activity	F	Catalysis of the reaction: H(2)O + O(2) + spermidine = 1,3-diaminopropane + 4-aminobutanal + H(2)O(2).
52897	N8-acetylspermidine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity	F	Catalysis of the reaction: H(2)O + N(8)-acetylspermidine + O(2) = 1,3-diaminopropane + 4-acetamidobutanal + H(2)O(2).
52898	N1-acetylspermidine:oxygen oxidoreductase (propane-1,3-diamine-forming) activity	F	Catalysis of the reaction: H(2)O + N(1)-acetylspermidine + O(2) = 1,3-diaminopropane + 4-acetamidobutanal + H(2)O(2).
52899	N(1),N(12)-diacetylspermine:oxygen oxidoreductase (3-acetamidopropanal-forming) activity	F	Catalysis of the reaction: H(2)O + N(1),N(12)-diacetylspermine + O(2) = 3-acetamidopropanal + H(2)O(2) + N(1)-acetylspermidine.
52900	spermine oxidase (propane-1,3-diamine-forming) activity	F	Catalysis of the reaction: H(2)O + O(2) + spermine = 1,3-diaminopropane + H(2)O(2) + N-(3-aminopropyl)-4-aminobutanal.
52901	spermine:oxygen oxidoreductase (spermidine-forming) activity	F	Catalysis of the reaction: H(2)O + O(2) + spermine = 3-aminopropanal + H(2)O(2) + spermidine.
52902	spermidine:oxygen oxidoreductase (3-aminopropanal-forming) activity	F	Catalysis of the reaction: H(2)O + O(2) + spermidine = 3-aminopropanal + H(2)O(2) + putrescine.
52903	N1-acetylspermine:oxygen oxidoreductase (3-acetamidopropanal-forming) activity	F	Catalysis of the reaction: H(2)O + N(1)-acetylspermine + O(2) = 3-acetamidopropanal + H(2)O(2) + spermidine.
52904	N1-acetylspermidine:oxygen oxidoreductase (3-acetamidopropanal-forming) activity	F	Catalysis of the reaction: H(2)O + N(1)-acetylspermidine + O(2) = 3-acetamidopropanal + H(2)O(2) + putrescine.
52905	tRNA (guanine(9)-N(1))-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + guanine(9) in tRNA = N(1)-methylguanine(9) in tRNA + S-adenosyl-L-homocysteine.
52906	tRNA (guanine(37)-N(1))-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + guanine(37) in tRNA = N(1)-methylguanine(37) in tRNA + S-adenosyl-L-homocysteine.
52907	23S rRNA (adenine(1618)-N(6))-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + adenine(1618) in 23S rRNA = S-adenosyl-L-homocysteine + rRNA containing N(6)-methyladenine(1618) in 23S rRNA.
52908	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity	F	Catalysis of the reaction: 4 S-adenosyl-L-methionine + adenine(1518)/adenine(1519) in 16S rRNA = 4 S-adenosyl-L-homocysteine + N(6)-dimethyladenine(1518)/N(6)-dimethyladenine(1519) in 16S rRNA.
52909	18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase activity	F	Catalysis of the reaction: 4 S-adenosyl-L-methionine + adenine(1779)/adenine(1780) in 18S rRNA = 4 S-adenosyl-L-homocysteine + N(6)-dimethyladenine(1779)/N(6)-dimethyladenine(1780) in 18S rRNA.
52910	23S rRNA (adenine(2085)-N(6))-dimethyltransferase activity	F	Catalysis of the reaction: 2 S-adenosyl-L-methionine + adenine(2085) in 23S rRNA = 2 S-adenosyl-L-homocysteine + N(6)-dimethyladenine(2085) in 23S rRNA.
52911	23S rRNA (guanine(745)-N(1))-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + guanine(745) in 23S rRNA = N(1)-methylguanine(745) in 23S rRNA + S-adenosyl-L-homocysteine.
52912	23S rRNA (guanine(748)-N(1))-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + guanine(748) in 23S rRNA = N(1)-methylguanine(748) in 23S rRNA + S-adenosyl-L-homocysteine.
52913	16S rRNA (guanine(966)-N(2))-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + guanosine(966) in 16S rRNA = N(2)-methylguanosine(966) in 16S rRNA + S-adenosyl-L-homocysteine.
52914	16S rRNA (guanine(1207)-N(2))-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + guanosine(1207) in 16S rRNA = N(2)-methylguanosine(1207) in 16S rRNA + S-adenosyl-L-homocysteine.
52915	23S rRNA (guanine(2445)-N(2))-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + guanosine(2445) in 23S rRNA = N(2)-methylguanosine(2445) in 23S rRNA + S-adenosyl-L-homocysteine.
52916	23S rRNA (guanine(1835)-N(2))-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + guanosine(1835) in 23S rRNA = N(2)-methylguanosine(1835) in 23S rRNA + S-adenosyl-L-homocysteine.
52917	dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase activity	F	Catalysis of the reaction: alpha-D-man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-(alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-alpha-D-Man-(1->6))-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc-diphosphodolichol + dolichyl D-mannosyl phosphate = H(+) + alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-(alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-(alpha-D-Man-(1->6))-alpha-D-Man-(1->6))-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc-diphosphodolichol + dolichyl phosphate.
52918	dol-P-Man:Man(8)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase activity	F	Catalysis of the reaction: alpha-D-man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-(alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-(alpha-D-Man-(1->6))-alpha-D-Man-(1->6))-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc-diphosphodolichol + dolichyl D-mannosyl phosphate = H(+) + alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-[alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-(alpha-D-Man-(1->2)-alpha-D-Man-(1->6))-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc-diphosphodolichol + dolichyl phosphate.
52919	aliphatic (R)-hydroxynitrile lyase activity	F	Catalysis of the reaction: an aliphatic (R)-hydroxynitrile = an aliphatic aldehyde or ketone + hydrogen cyanide.
52920	(2R)-2-hydroxy-2-methylbutanenitrile lyase activity	F	Catalysis of the reaction: (2R)-2-hydroxy-2-methylbutanenitrile = butan-2-one + hydrogen cyanide.
52921	acetone-cyanohydrin acetone-lyase (cyanide-forming) activity	F	Catalysis of the reaction: acetone cyanohydrin = hydrogen cyanide + acetone.
52922	hexaprenyl diphosphate synthase (geranylgeranyl-diphosphate specific) activity	F	Catalysis of the reaction: geranylgeranyl diphosphate + 2 isopentenyl diphosphate = 2 diphosphate + all-trans-hexaprenyl diphosphate.
52923	all-trans-nonaprenyl-diphosphate synthase (geranyl-diphosphate specific) activity	F	Catalysis of the reaction: geranyl diphosphate + 7 isopentenyl diphosphate = 7 diphosphate + all-trans-nonaprenyl diphosphate.
52924	all-trans-nonaprenyl-diphosphate synthase (geranylgeranyl-diphosphate specific) activity	F	Catalysis of the reaction: geranylgeranyl diphosphate + 5 isopentenyl diphosphate = 5 diphosphate + all-trans-nonaprenyl diphosphate.
52925	dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase activity	F	Catalysis of the reaction: an alpha-D-man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-(alpha-D-Man-(1->6))-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc-diphosphodolichol + dolichyl D-mannosyl phosphate = H(+) + alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-(alpha-D-Man-(1->3)-alpha-D-Man-(1->6))-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc-diphosphodolichol + dolichyl phosphate.
52926	dol-P-Man:Man(6)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase activity	F	Catalysis of the reaction: alpha-D-man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-(alpha-D-Man-(1->3)-alpha-D-Man-(1->6))-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc-diphosphodolichol + dolichyl D-mannosyl phosphate = H(+) + alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-(alpha-D-Man-(1->2)-alpha-D-Man-(1->3)-alpha-D-Man-(1->6))-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-D-GlcNAc-diphosphodolichol + dolichyl phosphate.
52927	CTP:tRNA cytidylyltransferase activity	F	Catalysis of the reaction: a tRNA precursor + CTP = a tRNA with a 3' cytidine end + diphosphate.
52928	CTP:3'-cytidine-tRNA cytidylyltransferase activity	F	Catalysis of the reaction: a tRNA with a 3' cytidine + CTP = a tRNA with a 3' CC end + diphosphate.
52929	ATP:3'-cytidine-cytidine-tRNA adenylyltransferase activity	F	Catalysis of the reaction: a tRNA with a 3' CC end + ATP = a tRNA with a 3' CCA end + diphosphate.
52930	methanol ferricytochrome-c oxidoreductase activity	F	Catalysis of the reaction: methanol + 2 ferricytochrome c = formaldehyde + 2 ferrocytochrome c + 2 H+.
52931	ethanol cytochrome-c oxidoreductase activity	F	Catalysis of the reaction: ethanol + 2 cytochrome c(L) = acetaldehyde + 2 reduced cytochrome c(L) + 2 H+.
52932	2-chloroethanol cytochrome-c oxidoreductase activity	F	Catalysis of the reaction: 2-chloroethanol + 2 cytochrome c(L) = chloroacetaldehyde + 2 reduced cytochrome c(L).
52933	alcohol dehydrogenase (cytochrome c(L)) activity	F	Catalysis of the reaction: primary alcohol + 2 cytochrome c(L) = 2 reduced cytochrome c(L) + an aldehyde + 2 H+.
52934	alcohol dehydrogenase (cytochrome c) activity	F	Catalysis of the reaction: primary alcohol + 2 cytochrome c = 2 reduced cytochrome c + an aldehyde + 2 H+.
52935	ethanol:cytochrome c oxidoreductase activity	F	Catalysis of the reaction: ethanol + 2 cytochrome c = 2 reduced cytochrome c + acetaldehyde.
52936	2-chloroethanol:cytochrome c oxidoreductase activity	F	Catalysis of the reaction: 2-chloroethanol + 2 cytochrome c = chloroacetaldehyde + 2 reduced cytochrome c.
55001	muscle cell development	P	The process whose specific outcome is the progression of a muscle cell over time, from its formation to the mature structure. Muscle cell development does not include the steps involved in committing an unspecified cell to the muscle cell fate.
55002	striated muscle cell development	P	The process whose specific outcome is the progression of a striated muscle cell over time, from its formation to the mature structure. Striated muscle cells contain fibers that are divided by transverse bands into striations, and cardiac and skeletal muscle are types of striated muscle.
55003	cardiac myofibril assembly	P	The process whose specific outcome is the progression of the cardiac myofibril over time, from its formation to the mature structure. A cardiac myofibril is a myofibril specific to cardiac muscle cells.
55004	atrial cardiac myofibril assembly	P	The process whose specific outcome is the progression of the atrial cardiac myofibril over time, from its formation to the mature structure. A cardiac myofibril is a myofibril specific to cardiac muscle cells.
55005	ventricular cardiac myofibril assembly	P	The process whose specific outcome is the progression of the ventricular cardiac myofibril over time, from its formation to the mature structure. A cardiac myofibril is a myofibril specific to cardiac muscle cells.
55006	cardiac cell development	P	The process whose specific outcome is the progression of a cardiac cell over time, from its formation to the mature state. A cardiac cell is a cell that will form part of the cardiac organ of an individual.
55007	cardiac muscle cell differentiation	P	The process in which a cardiac muscle precursor cell acquires specialized features of a cardiac muscle cell. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction.
55008	cardiac muscle tissue morphogenesis	P	The process in which the anatomical structures of cardiac muscle tissue are generated and organized.
55009	atrial cardiac muscle tissue morphogenesis	P	The process in which the anatomical structure of cardiac atrium muscle is generated and organized.
55010	ventricular cardiac muscle tissue morphogenesis	P	The process in which the anatomical structures of cardiac ventricle muscle is generated and organized.
55011	atrial cardiac muscle cell differentiation	P	The process in which a relatively unspecialized cell acquires specialized features of a cardiac muscle cell in the atrium. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction. The atrium is the part of the heart that receives blood into the organ.
55012	ventricular cardiac muscle cell differentiation	P	The process in which a relatively unspecialized cell acquires specialized features of a ventricular cardiac muscle cell. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction. The ventricle is the part of the heart that pumps blood out of the organ.
55013	cardiac muscle cell development	P	The process whose specific outcome is the progression of a cardiac muscle cell over time, from its formation to the mature state.
55014	atrial cardiac muscle cell development	P	The process whose specific outcome is the progression of an atrial cardiac muscle cell over time, from its formation to the mature state. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction. The atrium is the part of the heart that receives blood into the organ.
55015	ventricular cardiac muscle cell development	P	The process whose specific outcome is the progression of a ventricular cardiac muscle cell over time, from its formation to the mature state. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction. The ventricle is the part of the heart that pumps blood out of the organ.
55016	hypochord development	P	The process whose specific outcome is the progression of the hypochord over time, from its formation to the mature structure. The hypochord is a transient rod-like structure in the embryos of fish, lampreys and amphibians that is located immediately ventral to the notochord. The hypochord may play a role in positioning the dorsal aorta.
55017	cardiac muscle tissue growth	P	The increase in size or mass of a cardiac muscle, where the increase in size or mass has the specific outcome of the progression of the organism over time from one condition to another.
55018	regulation of cardiac muscle fiber development	P	Any process that modulates the frequency, rate or extent of cardiac muscle fiber development.
55019	negative regulation of cardiac muscle fiber development	P	Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle fiber development.
55020	positive regulation of cardiac muscle fiber development	P	Any process that activates, maintains or increases the frequency, rate or extent of cardiac muscle fiber development.
55021	regulation of cardiac muscle tissue growth	P	Any process that modulates the frequency, rate or extent of cardiac muscle growth.
55022	negative regulation of cardiac muscle tissue growth	P	Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle growth.
55023	positive regulation of cardiac muscle tissue growth	P	Any process that activates, maintains or increases the frequency, rate or extent of cardiac muscle growth.
55024	regulation of cardiac muscle tissue development	P	Any process that modulates the frequency, rate or extent of cardiac muscle tissue development.
55025	positive regulation of cardiac muscle tissue development	P	Any process that activates, maintains or increases the frequency, rate or extent of cardiac muscle tissue development.
55026	negative regulation of cardiac muscle tissue development	P	Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle tissue development.
55028	cortical microtubule	C	Arrays of microtubules underlying and connected to the plasma membrane in the cortical cytosol.
55029	nuclear DNA-directed RNA polymerase complex	C	A protein complex, located in the nucleus, that possesses DNA-directed RNA polymerase activity.
55031	gamma-tubulin large complex, equatorial microtubule organizing center	C	A complex of gamma tubulin and associated proteins thought to be formed by multimerization of gamma-tubulin small complexes located at equatorial microtubule organizing centers.
55032	gamma-tubulin large complex, spindle pole body	C	A complex of gamma tubulin and associated proteins thought to be formed by multimerization of gamma-tubulin small complexes located in the spindle pole body.
55033	gamma-tubulin large complex, interphase microtubule organizing center	C	A complex of gamma tubulin and associated proteins thought to be formed by multimerization of gamma-tubulin small complexes located at interphase microtubule organizing centers.
55034	Bolwig's organ development	P	The process whose specific outcome is the progression of the Bolwig's organ over time, from its formation to the mature structure. The larval eye in Drosophila is a relatively simple sensory system composed of Bolwig's organs: two clusters, each composed of 12 photoreceptor cells from which axons extend in a single fascicle to the brain.
55035	plastid thylakoid membrane	C	The lipid bilayer membrane of any thylakoid within a plastid.
55036	virion membrane	C	The lipid bilayer surrounding a virion.
55037	recycling endosome	C	An organelle consisting of a network of tubules that functions in targeting molecules, such as receptors transporters and lipids, to the plasma membrane.
55038	recycling endosome membrane	C	The lipid bilayer surrounding a recycling endosome.
55039	trichocyst	C	A crystalline exocytotic organelle composed of small, acidic proteins existing primarily as disulphide-linked dimers. The trichocyst is an organelle that releases long filamentous proteins that capture predators in "nets" to slow them down when the cell is disturbed. The protein is nontoxic and shaped like a long, striated, fibrous shaft.
55040	periplasmic flagellum	C	Flagellar filaments located in the periplasmic space; characterized in spirochetes, in which they are essential for shape and motility. Composed of a core surrounded by two sheath layers, the flagella rotate to allow migration of the cell through viscous media, which would not be possible using external flagella.
55041	cyclopentanol dehydrogenase activity	F	Catalysis of the reaction: cyclopentanol + NAD(+) = cyclopentanone + H(+) + NADH.
55042	5-valerolactone hydrolase activity	F	Catalysis of the reaction: 5-valerolactone + H2O = 5-hydroxyvalerate.
55043	5-oxovalerate dehydrogenase activity	F	Catalysis of the reaction: 5-oxovalerate + NADP+ + H2O = glutarate + NADPH + H+.
55044	symplast	C	The interconnected cell membranes and intracellular regions of a plant. The interconnections occur via the plasmodesmata.
55045	antipodal cell degeneration	P	The process in which the antipodal cells undergo programmed cell death.
55046	microgametogenesis	P	The process whose specific outcome is the progression of the pollen grain over time, from its formation as the microspore to the mature structure.
55047	generative cell mitosis	P	The process in which the generative cell divides by mitosis to form two haploid cells. These will subsequently differentiate into sperm cells.
55048	anastral spindle assembly	P	The aggregation, arrangement and bonding together of a set of components to form the spindle, the array of microtubules and associated molecules that serves to move duplicated chromosomes apart, in the absence of centrosomes. Formation is initiated by the nucleation of microtubules (MTs) in the vicinity of condensed chromatin. MTs then attach to and congress around the chromatin due to activity of microtubule motors. A bipolar spindle is formed by focusing of the terminal ends of the MT array into spindle poles by molecular motors and cross-linking proteins.
55049	astral spindle assembly	P	The aggregation, arrangement and bonding together of a set of components to form the spindle, the array of microtubules and associated molecules that serves to move duplicated chromosomes apart, in the presence of centrosomes.
55050	astral spindle assembly involved in male meiosis	P	The aggregation, arrangement and bonding together of a set of components to form the astral spindle in male meiotic cells.
55051	ATP-binding cassette (ABC) transporter complex, integrated substrate binding	C	A complex for the transport of metabolites out of the cell, consisting of 4 domains: two ATP-binding domains and two membrane spanning domains. In some cases, all 4 domains are contained on 1 polypeptide, while in others one ATP-binding domain and one membrane spanning domain are together on one polypeptide in what is called a "half transporter". Two "half-transporters" come together to form a functional transporter. Transport of the substrate across the membrane is driven by the hydrolysis of ATP.
55052	ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing	C	A complex for the transport of metabolites into the cell, consisting of 5 subunits: two ATP-binding subunits, two membrane spanning subunits, and one substrate-binding subunit. In organisms with two membranes, the substrate-binding protein moves freely in the periplasmic space and joins the other subunits only when bound with substrate. In organisms with only one membrane the substrate-binding protein is tethered to the cytoplasmic membrane and associated with the other subunits. Transport of the substrate across the membrane is driven by the hydrolysis of ATP.
55053	mannose:proton symporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: mannose + H+ = mannose + H+.
55054	fructose:proton symporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: fructose + H+ = fructose + H+.
55055	D-glucose:proton symporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: D-glucose + H+ = D-glucose + H+. Symporter activity enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported together in the same direction in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy. D-glucose is the dextrorotatory D-enantiomer of glucose.
55056	D-glucose transmembrane transporter activity	F	Enables the transfer of the D-enantiomer of the hexose monosaccharide glucose from one side of the membrane to the other.
55057	neuroblast division	P	The process resulting in the physical partitioning and separation of a neuroblast into daughter cells. A neuroblast is any cell that will divide and give rise to a neuron.
55058	symmetric neuroblast division	P	The process resulting in the physical partitioning and separation of a neuroblast into two equi-potent daughter cells.
55059	asymmetric neuroblast division	P	The process resulting in the physical partitioning and separation of a neuroblast into two daughter cells with different developmental potentials.
55060	asymmetric neuroblast division resulting in ganglion mother cell formation	P	Any process resulting in the physical partitioning and separation of a neuroblast into a neuroblast and a ganglion mother cell.
55062	phosphate ion homeostasis	P	Any process involved in the maintenance of an internal steady state of phosphate ions within an organism or cell.
55063	sulfate ion homeostasis	P	Any process involved in the maintenance of an internal steady state of sulfate ions within an organism or cell.
55064	chloride ion homeostasis	P	Any process involved in the maintenance of an internal steady state of chloride ions within an organism or cell.
55065	metal ion homeostasis	P	Any process involved in the maintenance of an internal steady state of metal ions within an organism or cell.
55067	monovalent inorganic cation homeostasis	P	Any process involved in the maintenance of an internal steady state of monovalent inorganic cations within an organism or cell.
55068	cobalt ion homeostasis	P	Any process involved in the maintenance of an internal steady state of cobalt ions within an organism or cell.
55069	zinc ion homeostasis	P	Any process involved in the maintenance of an internal steady state of zinc ions within an organism or cell.
55070	copper ion homeostasis	P	Any process involved in the maintenance of an internal steady state of copper ions within an organism or cell.
55071	manganese ion homeostasis	P	Any process involved in the maintenance of an internal steady state of manganese ions within an organism or cell.
55072	iron ion homeostasis	P	Any process involved in the maintenance of an internal steady state of iron ions within an organism or cell.
55073	cadmium ion homeostasis	P	Any process involved in the maintenance of an internal steady state of cadmium ions within an organism or cell.
55074	calcium ion homeostasis	P	Any process involved in the maintenance of an internal steady state of calcium ions within an organism or cell.
55075	potassium ion homeostasis	P	Any process involved in the maintenance of an internal steady state of potassium ions within an organism or cell.
55076	transition metal ion homeostasis	P	Any process involved in the maintenance of an internal steady state of transition metal ions within an organism or cell. A transition metal is an element whose atom has an incomplete d-subshell of extranuclear electrons, or which gives rise to a cation or cations with an incomplete d-subshell. Transition metals often have more than one valency state. Biologically relevant transition metals include vanadium, manganese, iron, copper, cobalt, nickel, molybdenum and silver.
55077	gap junction hemi-channel activity	F	A wide pore channel activity that enables the transport of a solute across a membrane via a gap junction hemi-channel. Two gap junction hemi-channels coupled together form a complete gap junction.
55078	sodium ion homeostasis	P	Any process involved in the maintenance of an internal steady state of sodium ions within an organism or cell.
55079	aluminum ion homeostasis	P	Any process involved in the maintenance of an internal steady state of aluminum ions within an organism or cell.
55080	cation homeostasis	P	Any process involved in the maintenance of an internal steady state of cations within an organism or cell.
55081	anion homeostasis	P	Any process involved in the maintenance of an internal steady state of anions within an organism or cell.
55082	cellular chemical homeostasis	P	Any biological process involved in the maintenance of an internal steady state of a chemical at the level of the cell.
55083	monovalent inorganic anion homeostasis	P	Any process involved in the maintenance of an internal steady state of monovalent inorganic anions within an organism or cell.
55085	transmembrane transport	P	The process in which a solute is transported across a lipid bilayer, from one side of a membrane to the other
55086	nucleobase-containing small molecule metabolic process	P	The cellular chemical reactions and pathways involving a nucleobase-containing small molecule: a nucleobase, a nucleoside, or a nucleotide.
55087	Ski complex	C	A protein complex that regulates RNA degradation by the exosome complex. In Saccharomyces the complex has a heterotetrameric stoichiometry consisting of one copy each of Ski2p and Ski3 and two copies of Ski8p.
55088	lipid homeostasis	P	Any process involved in the maintenance of an internal steady state of lipid within an organism or cell.
55089	fatty acid homeostasis	P	Any process involved in the maintenance of an internal steady state of fatty acid within an organism or cell.
55090	acylglycerol homeostasis	P	Any process involved in the maintenance of an internal steady state of acylglycerol within an organism or cell.
55091	phospholipid homeostasis	P	Any process involved in the maintenance of an internal steady state of phospholipid within an organism or cell.
55092	sterol homeostasis	P	Any process involved in the maintenance of an internal steady state of sterol within an organism or cell.
55093	response to hyperoxia	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating increased oxygen tension.
55094	response to lipoprotein particle	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipoprotein particle stimulus.
55095	lipoprotein particle mediated signaling	P	A series of molecular signals mediated by the detection of a lipoprotein particle.
55096	low-density lipoprotein particle mediated signaling	P	A series of molecular signals mediated by the detection of low-density lipoprotein particle.
55097	high density lipoprotein particle mediated signaling	P	A series of molecular signals mediated by the detection of high density lipoprotein particle.
55098	response to low-density lipoprotein particle	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a low-density lipoprotein particle stimulus.
55099	response to high density lipoprotein particle	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a high density lipoprotein particle stimulus.
55100	adiponectin binding	F	Interacting selectively and non-covalently with adiponectin, a protein hormone produced by adipose tissue that modulates a number of metabolic processes, including glucose regulation and fatty acid catabolism.
55102	lipase inhibitor activity	F	Stops, prevents or reduces the activity of a lipase, an enzyme that catalyzes of the hydrolysis of a lipid.
55103	ligase regulator activity	F	Modulates the activity of a ligase.
55104	ligase inhibitor activity	F	Stops, prevents or reduces the activity of a ligase.
55105	ubiquitin-protein transferase inhibitor activity	F	Stops, prevents or reduces the activity of a ubiquitin-protein transferase.
55106	ubiquitin-protein transferase regulator activity	F	Modulates the activity of a ubiquitin-protein transferase, an enzyme that catalyzes the covalent attachment of ubiquitin to lysine in a substrate protein.
55107	Golgi to secretory granule transport	P	The directed movement of proteins from the Golgi to a secretory granule. The secretory granule is a membrane-bounded particle, usually protein, formed in the granular endoplasmic reticulum and the Golgi complex.
55108	Golgi to transport vesicle transport	P	The directed movement of proteins from the Golgi to a transport vesicle. Continuously secreted proteins are sorted into transport vesicles that fuse with the plasma membrane, releasing their contents by exocytosis.
55109	invagination involved in gastrulation with mouth forming second	P	The infolding of the epithelial sheet into the embryo involved in deuterostomic gastrulation.
55110	involution involved in gastrulation with mouth forming second	P	The inturning of an epithelial sheet over the basal surface of an outer layer involved in deuterostomic gastrulation.
55111	ingression involved in gastrulation with mouth forming second	P	The migration of individual cells into the embryo involved in deuterostomic gastrulation.
55112	delamination involved in gastrulation with mouth forming second	P	The splitting or migration of one epithelial sheet into two involved in the process of deuterostomic gastrulation.
55113	epiboly involved in gastrulation with mouth forming second	P	The expansion of one cell sheet over other cells involved in deuterostomic gastrulation.
55114	oxidation-reduction process	P	A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons.
55115	entry into diapause	P	The dormancy process that results in entry into diapause. Diapause is a neurohormonally mediated, dynamic state of low metabolic activity. Associated characteristics of this form of dormancy include reduced morphogenesis, increased resistance to environmental extremes, and altered or reduced behavioral activity. Full expression develops in a species-specific manner, usually in response to a number of environmental stimuli that precede unfavorable conditions. Once diapause has begun, metabolic activity is suppressed even if conditions favorable for development prevail. Once initiated, only certain stimuli are capable of releasing the organism from this state, and this characteristic is essential in distinguishing diapause from hibernation.
55116	entry into reproductive diapause	P	The dormancy process that results in entry into reproductive diapause. Reproductive diapause is a form of diapause where the organism itself will remain fully active, including feeding and other routine activities, but the reproductive organs experience a tissue-specific reduction in metabolism, with characteristic triggering and releasing stimuli.
55117	regulation of cardiac muscle contraction	P	Any process that modulates the frequency, rate or extent of cardiac muscle contraction.
55118	negative regulation of cardiac muscle contraction	P	Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle contraction.
55119	relaxation of cardiac muscle	P	The process in which the extent of cardiac muscle contraction is reduced.
55120	striated muscle dense body	C	A vinculin-containing myofibril attachment structure of striated muscle that connects sarcomeres to the extracellular matrix. In nematode body wall muscle, the dense body performs the dual role of Z-disk and costamere.
55121	response to high fluence blue light stimulus by blue high-fluence system	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the detection of a high fluence blue light stimulus by the blue high-fluence system. Blue light is electromagnetic radiation with a wavelength of between 440 and 500nm. The blue high-fluence system responds to blue light at levels between 100 and 1000 micromols/m2.
55122	response to very low light intensity stimulus	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a very low light intensity stimulus. A very low light intensity stimulus is defined as a level of electromagnetic radiation below 0.001 mmol/m2/sec.
55123	digestive system development	P	The process whose specific outcome is the progression of the digestive system over time, from its formation to the mature structure. The digestive system is the entire structure in which digestion takes place. Digestion is all of the physical, chemical, and biochemical processes carried out by multicellular organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism.
55127	vibrational conductance of sound to the inner ear	P	The transmission of vibrations via ossicles to the inner ear.
55129	L-proline biosynthetic process	P	The chemical reactions and pathways resulting in the formation of L-proline, an L-enantiomer of a chiral, cyclic, nonessential alpha-amino acid found in peptide linkage in proteins.
55130	D-alanine catabolic process	P	The chemical reactions and pathways resulting in the breakdown of D-alanine, the D-enantiomer of the amino acid alanine.
55131	C3HC4-type RING finger domain binding	F	Interacting selectively and non-covalently with a C3HC4-type zinc finger domain of a protein. The C3HC4-type zinc finger is a variant of RING finger, is a cysteine-rich domain of 40 to 60 residues that coordinates two zinc ions, and has the consensus sequence: C-X2-C-X(9-39)-C-X(1-3)-H-X(2-3)-C-X2-C-X(4-48)-C-X2-C, where X is any amino acid. Many proteins containing a C3HC4-type RING finger play a key role in the ubiquitination pathway.
60001	minus-end directed microfilament motor activity	F	Catalysis of movement along a microfilament towards the minus end, coupled to the hydrolysis of a nucleoside triphosphate (usually ATP). The minus end of an actin filament is the end that does not preferentially add actin monomers.
60002	plus-end directed microfilament motor activity	F	Catalysis of movement along a microfilament towards the plus end, coupled to the hydrolysis of a nucleoside triphosphate (usually ATP). The plus end of an actin filament is the end that preferentially adds actin monomers.
60003	copper ion export	P	The directed movement of copper ions out of a cell or organelle.
60004	reflex	P	An automatic response to a stimulus beginning with a nerve impulse from a receptor and ending with the action of an effector such as a gland or a muscle. Signaling never reaches a level of consciousness.
60005	vestibular reflex	P	A reflex process in which a response to an angular or linear acceleration stimulus begins with an afferent nerve impulse from a receptor in the inner ear and ends with the compensatory action of eye muscles. Signaling never reaches a level of consciousness.
60006	angular vestibuloocular reflex	P	A vestibular reflex by which a response to an angular acceleration stimulus begins with an afferent nerve impulse from a receptor in the semi-circular canal and ends with the compensatory action of eye muscles. Signaling never reaches a level of consciousness.
60007	linear vestibuloocular reflex	P	A vestibular reflex by which a response to a linear acceleration stimulus begins with an afferent nerve impulse from a receptor in the otolith and ends with the compensatory action of eye muscles. Signaling never reaches a level of consciousness.
60008	Sertoli cell differentiation	P	The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a Sertoli cell. A Sertoli cell is a supporting cell projecting inward from the basement membrane of seminiferous tubules.
60009	Sertoli cell development	P	The process whose specific outcome is the progression of a Sertoli cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a Sertoli cell fate.
60010	Sertoli cell fate commitment	P	The process in which the cellular identity of Sertoli cells is acquired and determined.
60011	Sertoli cell proliferation	P	The multiplication or reproduction of Sertoli cells, resulting in the expansion of the Sertoli cell population. A Sertoli cell is a supporting cell projecting inward from the basement membrane of seminiferous tubules.
60012	synaptic transmission, glycinergic	P	The process of communication from a neuron to another neuron across a synapse using the neurotransmitter glycine.
60013	righting reflex	P	A reflex process in which an animal immediately tries to turn over after being placed in a supine position.
60014	granulosa cell differentiation	P	The process in which a relatively unspecialized cell acquires the specialized features of a granulosa cell, a supporting cell for the developing female gamete in the ovary of mammals.
60015	granulosa cell fate commitment	P	The cell fate commitment of precursor cells that will become granulosa cells.
60016	granulosa cell development	P	The process whose specific outcome is the progression of a granulosa cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a granulosa cell fate.
60017	parathyroid gland development	P	The process whose specific outcome is the progression of the parathyroid gland over time, from its formation to the mature structure. The parathyroid gland is an organ specialised for secretion of parathyroid hormone.
60018	astrocyte fate commitment	P	The commitment of a cells to a specific astrocyte fate and its restriction to develop only into an astrocyte.
60019	radial glial cell differentiation	P	The process in which neuroepithelial cells of the neural tube give rise to radial glial cells, specialized bipotential progenitors cells of the brain. Differentiation includes the processes involved in commitment of a cell to a specific fate.
60020	Bergmann glial cell differentiation	P	The process in which neuroepithelial cells of the neural tube give rise to Brgmann glial cells, specialized bipotential progenitors cells of the cerebellum. Differentiation includes the processes involved in commitment of a cell to a specific fate.
60021	palate development	P	The biological process whose specific outcome is the progression of the palate from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure. The palate is the partition that separates the nasal and oral cavities.
60022	hard palate development	P	The biological process whose specific outcome is the progression of the hard palate from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. The hard palate is the anterior portion of the palate consisting of bone and mucous membranes.
60023	soft palate development	P	The biological process whose specific outcome is the progression of the soft palate from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure, whatever form that may be including its natural destruction. The soft palate is the posterior portion of the palate extending from the posterior edge of the hard palate.
60024	rhythmic synaptic transmission	P	Any process involved in the generation of rhythmic, synchronous synaptic inputs in a neural circuit.
60025	regulation of synaptic activity	P	Any process that modulates the frequency, rate or extent of synaptic activity, the controlled release of neurotransmitters into the synaptic cleft and their subsequent detection by a postsynaptic cell.
60026	convergent extension	P	The morphogenetic process in which an epithelium narrows along one axis and lengthens in a perpendicular axis.
60027	convergent extension involved in gastrulation	P	The morphogenetic process in which an epithelium narrows along one axis and lengthens in a perpendicular axis usually resulting in the formation of the three primary germ layers, ectoderm, mesoderm and endoderm.
60028	convergent extension involved in axis elongation	P	The morphogenetic process in which an epithelium narrows along one axis and lengthens in a perpendicular axis contributing to the lengthening of the axis of an organism.
60029	convergent extension involved in organogenesis	P	The morphogenetic process in which an epithelium narrows along one axis and lengthens in a perpendicular axis contribution to the shaping of an organ.
60030	dorsal convergence	P	The directed migration of individual cells and small groups of cells toward the dorsal midline during gastrulation. This process does not require cell rearrangement.
60031	mediolateral intercalation	P	The interdigitation of cells along the mediolateral axis during gastrulation.
60032	notochord regression	P	The developmental process in which the stucture of the notochord is destroyed in an embryo.
60033	anatomical structure regression	P	The developmental process in which an anatomical stucture is destroyed as a part of its normal progression.
60034	notochord cell differentiation	P	The process in which relatively unspecialized cells acquire specialized structural and/or functional features cells that make up the notochord. Differentiation includes the processes involved in commitment of a cell to a notochord cell fate.
60035	notochord cell development	P	The process whose specific outcome is the progression of a notochord cell over time, from its formation to its mature structure. Cell development does not include the steps involved in committing a cell to a specific fate.
60036	notochord cell vacuolation	P	The assembly and arrangement of a vacuole within a cell of the notochord.
60037	pharyngeal system development	P	The process whose specific outcome is the progression of the pharyngeal system over time, from its formation to the mature structure. The pharyngeal system is a transient embryonic complex that is specific to vertebrates. It comprises the pharyngeal arches, bulges of tissues of mesoderm and neural crest derivation through which pass nerves and pharyngeal arch arteries. The arches are separated internally by pharyngeal pouches, evaginations of foregut endoderm, and externally by pharyngeal clefts, invaginations of surface ectoderm. The development of the system ends when the stucture it contributes to are forming: the thymus, thyroid, parathyroids, maxilla, mandible, aortic arch, cardiac outflow tract, external and middle ear.
60038	cardiac muscle cell proliferation	P	The expansion of a cardiac muscle cell population by cell division.
60039	pericardium development	P	The process whose specific outcome is the progression of the pericardium over time, from its formation to the mature structure. The pericardium is a double-walled sac that contains the heart and the roots of the aorta, vena cava and the pulmonary artery.
60040	retinal bipolar neuron differentiation	P	The process in which a relatively unspecialized cell acquires specialized features of a bipolar cell, the last neuron to be generated in the retina.
60041	retina development in camera-type eye	P	The process whose specific outcome is the progression of the retina over time, from its formation to the mature structure. The retina is the innermost layer or coating at the back of the eyeball, which is sensitive to light and in which the optic nerve terminates.
60042	retina morphogenesis in camera-type eye	P	The process in which the anatomical structure of the retina is generated and organized.
60043	regulation of cardiac muscle cell proliferation	P	Any process that modulates the frequency, rate or extent of cardiac muscle cell proliferation.
60044	negative regulation of cardiac muscle cell proliferation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac muscle cell proliferation.
60045	positive regulation of cardiac muscle cell proliferation	P	Any process that activates or increases the frequency, rate or extent of cardiac muscle cell proliferation.
60046	regulation of acrosome reaction	P	Any process that modulates the frequency, rate or extent of the acrosome reaction.
60047	heart contraction	P	The multicellular organismal process in which the heart decreases in volume in a characteristic way to propel blood through the body.
60048	cardiac muscle contraction	P	Muscle contraction of cardiac muscle tissue.
60049	regulation of protein glycosylation	P	Any process that modulates the frequency, rate or extent of protein glycosylation. Protein glycosylation is the addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid, e.g. the addition of glycan chains to proteins.
60050	positive regulation of protein glycosylation	P	Any process that activates or increases the frequency, rate or extent of the glycosylation of one or more amino acid residues within a protein. Protein glycosylation is the addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid, e.g. the addition of glycan chains to proteins.
60051	negative regulation of protein glycosylation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the glycosylation of one or more amino acid residues within a protein. Protein glycosylation is the addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid, e.g. the addition of glycan chains to proteins.
60052	neurofilament cytoskeleton organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising neurofilaments and their associated proteins.
60053	neurofilament cytoskeleton	C	Intermediate filament cytoskeletal structure that is made up of neurofilaments. Neurofilaments are specialized intermediate filaments found in neurons.
60054	positive regulation of epithelial cell proliferation involved in wound healing	P	Any process that activates or increases the rate or extent of epithelial cell proliferation, contributing to the restoration of integrity to a damaged tissue following an injury.
60055	angiogenesis involved in wound healing	P	Blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels and contribute to the series of events that restore integrity to a damaged tissue, following an injury.
60056	mammary gland involution	P	The tissue remodeling that removes differentiated mammary epithelia during weaning.
60057	apoptotic process involved in mammary gland involution	P	Any apoptotic process that triggers the activity of proteolytic caspases whose actions dismantle the mammary epithelial cells resulting in their programmed cell death.
60058	positive regulation of apoptotic process involved in mammary gland involution	P	Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process of mammary epithelial cells during mammary gland involution.
60059	embryonic retina morphogenesis in camera-type eye	P	The process in which the anatomical structure of the retina is generated and organized in a camera-type eye during the embryonic life stage.
60060	post-embryonic retina morphogenesis in camera-type eye	P	The process in which the anatomical structure of the retina is generated and organized in a camera-type eye during the post-embryonic life stage.
60061	Spemann organizer formation	P	Formation of the specialized region on the dorsalmost side of the embryo that acts as the main signaling center establishing the vertebrate body plan.
60062	Spemann organizer formation at the dorsal lip of the blastopore	P	Formation of the specialized region at the dorsal lip of the blatopore of the embryo that acts as the main signaling center establishing the vertebrate body plan.
60063	Spemann organizer formation at the embryonic shield	P	Formation of the specialized region of the embryonic shield of the embryo that acts as the main signaling center establishing the teleost body plan.
60064	Spemann organizer formation at the anterior end of the primitive streak	P	Formation of the specialized region at the anterior end of the primitive streak of the embryo that acts as the main signaling center establishing the body plan.
60065	uterus development	P	The reproductive developmental process whose specific outcome is the progression of the uterus over time, from its formation to the mature structure.
60066	oviduct development	P	The reproductive developmental process whose specific outcome is the progression of an oviduct over time, from its formation to the mature structure. An oviduct is a tube through which an ova passes from the ovary to the uterus, or from the ovary to the outside of the organism.
60067	cervix development	P	The reproductive developmental process whose specific outcome is the progression of the cervix over time, from its formation to the mature structure.
60068	vagina development	P	The reproductive developmental process whose specific outcome is the progression of the vagina over time, from its formation to the mature structure.
60069	Wnt signaling pathway, regulating spindle positioning	P	The series of molecular signals initiated by binding of Wnt protein to a frizzled family receptor on the surface of the target cell and ending with the positioning of the mitotic spindle.
60070	canonical Wnt signaling pathway	P	The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes. In this pathway, the activated receptor signals via downstream effectors that result in the inhibition of beta-catenin phosphorylation, thereby preventing degradation of beta-catenin. Stabilized beta-catenin can then accumulate and travel to the nucleus to trigger changes in transcription of target genes.
60071	Wnt signaling pathway, planar cell polarity pathway	P	The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors including C-Jun N-terminal kinase (JNK) to modulate cytoskeletal elements and control cell polarity.
60072	large conductance calcium-activated potassium channel activity	F	Enables the transmembrane transfer of potassium by a channel with a unit conductance of 100 to 220 picoSiemens that opens in response to stimulus by concerted actions of internal calcium ions and membrane potential. Large conductance calcium-activated potassium channels are less sensitive to calcium than are small or intermediate conductance calcium-activated potassium channels. Transport by a channel involves catalysis of facilitated diffusion of a solute (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel, without evidence for a carrier-mediated mechanism.
60073	micturition	P	The regulation of body fluids process in which parasympathetic nerves stimulate the bladder wall muscle to contract and expel urine from the body.
60074	synapse maturation	P	The process that organizes a synapse so that it attains its fully functional state. Synaptic maturation plays a critical role in the establishment of effective synaptic connections in early development.
60075	regulation of resting membrane potential	P	Any process that modulates the establishment or extent of a resting potential, the electrical charge across the plasma membrane, with the interior of the cell negative with respect to the exterior. The resting potential is the membrane potential of a cell that is not stimulated to be depolarized or hyperpolarized.
60076	excitatory synapse	C	A synapse in which an action potential in the presynaptic cell increases the probability of an action potential occurring in the postsynaptic cell.
60077	inhibitory synapse	C	A synapse in which an action potential in the presynaptic cell reduces the probability of an action potential occurring in the postsynaptic cell.
60078	regulation of postsynaptic membrane potential	P	Any process that modulates the potential difference across a post-synaptic membrane.
60079	excitatory postsynaptic potential	P	A process that leads to a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell. The flow of ions that causes an EPSP is an excitatory postsynaptic current (EPSC) and makes it easier for the neuron to fire an action potential.
60080	inhibitory postsynaptic potential	P	A process that causes a temporary decrease in postsynaptic membrane potential due to the flow of negatively charged ions into the postsynaptic cell. The flow of ions that causes an IPSP is an inhibitory postsynaptic current (IPSC) and makes it more difficult for the neuron to fire an action potential.
60081	membrane hyperpolarization	P	The process in which membrane potential increases with respect to its steady-state potential, usually from negative potential to a more negative potential. For example, during the repolarization phase of an action potential the membrane potential often becomes more negative or hyperpolarized before returning to the steady-state resting potential.
60082	eye blink reflex	P	The reflex process in which a mechanical stimulus applied to the eye elicits a response of the eyelid closing.
60083	smooth muscle contraction involved in micturition	P	The process leading to shortening and/or development of tension in the urinary bladder smooth muscle tissue involved in the expulsion urine from the body.
60084	synaptic transmission involved in micturition	P	The process of communication from a neuron to a smooth muscle in the bladder that contributes to the expulsion of urine from the body.
60085	smooth muscle relaxation of the bladder outlet	P	A process in which the extent of smooth muscle contraction is reduced in the bladder outlet that contributes to the expulsion of urine from the body.
60086	circadian temperature homeostasis	P	Any homeostatic process in which an organism modulates its internal body temperature at different values with a regularity of approximately 24 hours.
60087	relaxation of vascular smooth muscle	P	A process in which the extent of vascular smooth muscle contraction is reduced. Vascular smooth muscle relaxation is mediated via a decrease in the phosphorylation state of myosin light chain. This can be achieved by removal of calcium from the cytoplasm to the sarcoplasmic reticulum lumen through the action of Ca2+ ATPases leading to a decrease myosin light chain kinase activity, and through calcium-independent pathways leading to a increase in myosin light chain phosphatase activity.
60088	auditory receptor cell stereocilium organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a stereocilium. A stereocilium is an actin-based protrusion from the apical surface of auditory hair cells.
60089	molecular transducer activity	F	The molecular function that accepts an input of one form and creates an output of a different form.
60090	binding, bridging	F	The binding activity of a molecule that brings together two or more molecules through a selective, non-covalent, often stoichiometric interaction, permitting those molecules to function in a coordinated way.
60091	kinocilium	C	A nonmotile primary cilium that is found at the apical surface of auditory receptor cells. The kinocilium is surrounded by actin-based stereocilia.
60092	regulation of synaptic transmission, glycinergic	P	Any process that modulates the frequency, rate or extent of glycinergic synaptic transmission. Glycinergic synaptic transmission is the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glycine.
60093	negative regulation of synaptic transmission, glycinergic	P	Any process that stops or decreases the frequency, rate or extent of glycinergic synaptic transmission. Glycinergic synaptic transmission is the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glycine.
60094	positive regulation of synaptic transmission, glycinergic	P	Any process that activates or increases the frequency, rate or extent of glycinergic synaptic transmission. Glycinergic synaptic transmission is the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glycine.
60095	zinc potentiation of synaptic transmission, glycinergic	P	Any process that activates or increases the frequency, rate or extent of glycinergic synaptic transmission in the presence of zinc. Glycinergic synaptic transmission is the process of communication from a neuron to another neuron across a synapse using the neurotransmitter glycine.
60096	serotonin secretion, neurotransmission	P	The regulated release of serotonin by a cell, in which released serotonin acts as a neurotransmitter.
60097	cytoskeletal rearrangement involved in phagocytosis, engulfment	P	The assembly, arrangement, or disassembly of cytoskeletal structures that is involved in the internalization of bacteria, immune complexes and other particulate matter or of an apoptotic cell by phagocytosis.
60098	membrane reorganization involved in phagocytosis, engulfment	P	The assembly and arrangement of the plasma membrane that is involved in the internalization of bacteria, immune complexes and other particulate matter or of an apoptotic cell by phagocytosis.
60099	regulation of phagocytosis, engulfment	P	Any process that modulates the frequency, rate or extent of the internalization of bacteria, immune complexes and other particulate matter or of an apoptotic cell by phagocytosis.
60100	positive regulation of phagocytosis, engulfment	P	Any process that activates or increases the frequency, rate or extent of the internalization of bacteria, immune complexes and other particulate matter or of an apoptotic cell by phagocytosis.
60101	negative regulation of phagocytosis, engulfment	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the internalization of bacteria, immune complexes and other particulate matter or of an apoptotic cell by phagocytosis.
60102	collagen and cuticulin-based cuticle extracellular matrix	C	A collagen and cuticulin-based noncellular, multilayered structure that is synthesized by an underlying ectodermal (hypodermal) cell layer. The cuticle serves essential functions in body morphology, locomotion, and environmental protection. An example of this component is found in Caenorhabditis elegans.
60103	collagen and cuticulin-based cuticle extracellular matrix part	C	Any constituent part of the collagen and cuticulin-based cuticle extracellular matrix, a collagen and cuticulin-based noncellular, multilayered structure that is synthesized by an underlying ectodermal (hypodermal) cell layer.
60104	surface coat of collagen and cuticulin-based cuticle extracellular matrix	C	An electron dense, amorphous envelope that comprises the outermost layer of the cuticle. The surface coat is loosely apposed to the epicuticle, has distinct biochemical properties, is synthesized by cells other than the underlying hypodermis, and is labile. In addition to serving as a lubricant to protect against abrasion and dehydration, the surface coat may also play important roles in infection and immune evasion. An example of this component is found in Caenorhabditis elegans.
60105	epicuticle of collagen and cuticulin-based cuticle extracellular matrix	C	A lipid-containing layer of cuticle that lies between the cortical layer and the surface coat. An example of this component is found in Caenorhabditis elegans.
60106	cortical layer of collagen and cuticulin-based cuticle extracellular matrix	C	The cuticle layer that lies directly beneath the lipid-containing epicuticle. The cortical layer contains collagens and insoluble, non-collagenous cuticulins and is characterized by a distinct annular pattern consisting of regularly spaced annular ridges delineated by annular furrows. An example of this component is found in Caenorhabditis elegans.
60107	annuli extracellular matrix	C	The extracellular matrix that is a regularly spaced circumferential ridge present in the cortical region of the cuticle. Annuli are delineated by annular furrows and are present throughout the cuticle with the exception of lateral regions where longitudinal alae are present.
60108	annular furrow extracellular matrix	C	The extracellular matrix part that is a regularly spaced indentation in the outer cortical layer of the cuticle. The pattern of annular furrows corresponds to sites of invaginations in hypodermal cell membranes that, in turn, correspond to submembranous regions where actin microfilament bundles assemble early in lethargus, the first phase of the molting cycle in which activity and feeding decline.
60109	medial layer of collagen and cuticulin-based cuticle extracellular matrix	C	The fluid-filled cuticle layer that lies between the cortical and basal layers and is characterized by the presence of regularly spaced columnar struts that lie on either side of the annular furrows and link the two surrounding layers. In C. elegans, a defined medial layer is found only in adult animals.
60110	basal layer of collagen and cuticulin-based cuticle extracellular matrix	C	The layer of cuticle most closely apposed to the hypodermal cells. The morphology of the basal layer varies with life stage. In adult C. elegans animals, the basal layers is comprised of three sublayers: two fibrous layers whose fibers run in clockwise and counter-clockwise directions meeting one another at a 60 degree angle, and an amorphous basal layer that lies underneath the fibrous layers and directly contacts the hypodermis. In C. elegans dauer and L1 larval stage animals, the basal layer is characterized by a striated pattern that appears to derive from interwoven laminae. An example of this component is found in Caenorhabditis elegans.
60111	alae of collagen and cuticulin-based cuticle extracellular matrix	C	Raised, thickened cuticular ridges that run longitudinally, and in parallel, along the left and right sides of the animal. The alae lie above the hypodermal cells known as the lateral seam cells. In C. elegans, alae are produced in L1 larvae, dauer larvae and adult stage animals, where they consist of three, five, and three ridges of distinct morphology, respectively.
60112	generation of ovulation cycle rhythm	P	The process which controls the timing of the type of sexual cycle seen in female mammals.
60113	inner ear receptor cell differentiation	P	The process in which relatively unspecialized cells, acquire specialized structural and/or functional features of inner ear receptor cells. Inner ear receptor cells are mechanorecptors found in the inner ear responsible for transducing signals involved in balance and sensory perception of sound.
60114	vestibular receptor cell differentiation	P	The process in which a relatively unspecialized cell acquires specialized features of a vestibular hair cell.
60115	vestibular receptor cell fate commitment	P	The process in which a cell becomes committed to become a vestibular receptor cell.
60116	vestibular receptor cell morphogenesis	P	Any process that alters the size or shape of a vestibular receptor cell.
60117	auditory receptor cell development	P	The process whose specific outcome is the progression of an auditory receptor cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate.
60118	vestibular receptor cell development	P	The process whose specific outcome is the progression of a vestibular receptor cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate.
60119	inner ear receptor cell development	P	The process whose specific outcome is the progression of an inner ear receptor cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate.
60120	inner ear receptor cell fate commitment	P	The process in which a cell becomes committed to become an inner ear receptor cell.
60121	vestibular receptor cell stereocilium organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a stereocilium. A stereocilium is an actin-based protrusion from the apical surface of vestibular hair cells.
60122	inner ear receptor stereocilium organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a stereocilium. A stereocilium is an actin-based protrusion from the apical surface of inner ear receptor cells.
60123	regulation of growth hormone secretion	P	Any process that modulates the frequency, rate or extent of the regulated release of growth hormone from a cell.
60124	positive regulation of growth hormone secretion	P	Any process that increases the frequency, rate or extent of the regulated release of growth hormone from a cell.
60125	negative regulation of growth hormone secretion	P	Any process that decreases or stops the frequency, rate or extent of the regulated release of growth hormone from a cell.
60126	somatotropin secreting cell differentiation	P	The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a somatotropin secreting cell. A somatotropin secreting cell is an acidophilic cell of the anterior pituitary that produces growth hormone, somatotropin.
60127	prolactin secreting cell differentiation	P	The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a prolactin secreting cell. A prolactin secreting cell is an acidophilic cell of the anterior pituitary that produces prolactin.
60128	corticotropin hormone secreting cell differentiation	P	The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a corticotropic hormone secreting cell. An corticotropic hormone secreting cell is a basophil cell of the anterior pituitary that produces corticotropin.
60129	thyroid-stimulating hormone-secreting cell differentiation	P	The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a thyroid-stimulating hormone-secreting cell. A thyroid-stimulating hormone-secreting cell is a basophil cell of the anterior pituitary that produces thyroid-stimulating hormone, thyrotrophin.
60130	thyroid-stimulating hormone-secreting cell development	P	The process whose specific outcome is the progression of a thyroid-stimulating hormone-secreting cell over time, from its formation to the mature structure. A thyroid-stimulating hormone-secreting cell is a basophil cell of the anterior pituitary that produces thyroid stimulating hormone, thyrotrophin.
60131	corticotropin hormone secreting cell development	P	The process whose specific outcome is the progression of a corticotropic hormone secreting cell over time, from its formation to the mature structure. An corticotropic hormone secreting cell is a basophil cell of the anterior pituitary that produces corticotropin.
60132	prolactin secreting cell development	P	The process whose specific outcome is the progression of a prolactin secreting cell over time, from its formation to the mature structure. A prolactin secreting cell is an acidophilic cell of the anterior pituitary that produces prolactin.
60133	somatotropin secreting cell development	P	The process whose specific outcome is the progression of a somatotropin secreting cell over time, from its formation to the mature structure. A somatotropin secreting cell is an acidophilic cell of the anterior pituitary that produces growth hormone, somatotropin.
60134	prepulse inhibition	P	The process in which a startle magnitude is reduced when the startling stimulus is preceded by a low-intensity prepulse.
60135	maternal process involved in female pregnancy	P	A reproductive process occurring in the mother that allows an embryo or fetus to develop within it.
60136	embryonic process involved in female pregnancy	P	A reproductive process occurring in the embryo or fetus that allows the embryo or fetus to develop within the mother.
60137	maternal process involved in parturition	P	A reproductive process occurring in the mother that results in birth.
60138	fetal process involved in parturition	P	A reproductive process occurring in the embryo that results in birth.
60139	positive regulation of apoptotic process by virus	P	Any viral process that activates or increases the frequency, rate or extent of cell death by apoptotic process.
60140	modulation by virus of syncytium formation via plasma membrane fusion	P	The formation in a cell that has been targeted by a virus of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells.
60141	positive regulation of syncytium formation by virus	P	The process in which a virus increases the frequency, rate or extent of the formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells.
60142	regulation of syncytium formation by plasma membrane fusion	P	Any process that modulates the frequency, rate or extent of the formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells.
60143	positive regulation of syncytium formation by plasma membrane fusion	P	Any process that increases the frequency, rate or extent of the formation of a syncytium, a mass of cytoplasm containing several nuclei enclosed within a single plasma membrane, by the fusion of the plasma membranes of two or more individual cells.
60144	host cellular process involved in virus induced gene silencing	P	A cellular process occurring in the host cell that contributes to the process of posttranscriptional gene inactivation ('silencing') both of viral gene(s), and host gene(s) homologous to the viral genes.
60145	viral gene silencing in virus induced gene silencing	P	The posttranscriptional gene silencing of viral genes after viral infection.
60146	host gene silencing in virus induced gene silencing	P	The posttranscriptional gene silencing of host genes that are homologous to viral genes after viral infection.
60147	regulation of posttranscriptional gene silencing	P	Any process that modulates the frequency, rate or extent of the inactivation of gene expression by a posttranscriptional mechanism.
60148	positive regulation of posttranscriptional gene silencing	P	Any process that increases the frequency, rate or extent of the inactivation of gene expression by a posttranscriptional mechanism.
60149	negative regulation of posttranscriptional gene silencing	P	Any process that decreases the frequency, rate or extent of the inactivation of gene expression by a posttranscriptional mechanism.
60150	viral triggering of virus induced gene silencing	P	Any process that increases the frequency, rate or extent of the inactivation of gene expression of both viral genes and host homologues to those genes by a posttranscriptional mechanism in a virally infected cell.
60151	peroxisome localization	P	Any process in which a peroxisome is transported to, and/or maintained in, a specific location. A peroxisome is a small membrane-bounded organelle that uses dioxygen (O2) to oxidize organic molecules.
60152	microtubule-based peroxisome localization	P	The microtubule-based process in which a peroxisome is transported to, and/or maintained in, a specific location. A peroxisome is a small membrane-bounded organelle that uses dioxygen (O2) to oxidize organic molecules.
60153	modulation by virus of host cell cycle	P	Any viral process that modulates the rate or extent of progression through the cell cycle.
60154	cellular process regulating host cell cycle in response to virus	P	Any cellular process that modulates the rate or extent of progression through the cell cycle in response to a virus.
60155	platelet dense granule organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a platelet dense granule. A platelet dense granule is an electron-dense granule occurring in blood platelets that stores and secretes adenosine nucleotides and serotonin. They contain a highly condensed core consisting of serotonin, histamine, calcium, magnesium, ATP, ADP, pyrophosphate and membrane lysosomal proteins.
60156	milk ejection reflex	P	A reflex that occurs in response to suckling, beginning with a nerve impulse from a receptor in the mammary gland and ending with the ejection of milk from the gland. Signaling never reaches a level of consciousness.
60157	urinary bladder development	P	The process whose specific outcome is the progression of the urinary bladder over time, from its formation to the mature structure. The urinary bladder is an elastic, muscular sac situated in the anterior part of the pelvic cavity in which urine collects before excretion.
60158	phospholipase C-activating dopamine receptor signaling pathway	P	The series of molecular signals generated as a consequence of a dopamine receptor binding to its physiological ligand, where the pathway proceeds with activation of phospholipase C (PLC) and a subsequent release of inositol trisphosphate (IP3) and diacylglycerol (DAG).
60159	regulation of dopamine receptor signaling pathway	P	Any process that modulates the frequency, rate or extent of a dopamine receptor signaling pathway activity. A dopamine receptor signaling pathway is the series of molecular signals generated as a consequence of a dopamine receptor binding to one of its physiological ligands.
60160	negative regulation of dopamine receptor signaling pathway	P	Any process that stops, prevents, or reduces the frequency, rate or extent of dopamine receptor protein signaling pathway activity. A dopamine receptor signaling pathway is the series of molecular signals generated as a consequence of a dopamine receptor binding to one of its physiological ligands.
60161	positive regulation of dopamine receptor signaling pathway	P	Any process that activates or increases the frequency, rate or extent of the dopamine receptor protein signaling pathway. A dopamine receptor signaling pathway is the series of molecular signals generated as a consequence of a dopamine receptor binding to one of its physiological ligands.
60162	negative regulation of phospholipase C-activating dopamine receptor signaling pathway	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the dopamine receptor, phospholipase C activating pathway.
60163	subpallium neuron fate commitment	P	The process in which in the subpallium, the developmental fate of a cell becomes restricted such that it will develop into a neuron. The subpallium is the base region of the telencephalon.
60164	regulation of timing of neuron differentiation	P	The process controlling the activation and/or rate at which a relatively unspecialized cell acquires features of a neuron.
60165	regulation of timing of subpallium neuron differentiation	P	The process controlling the timing and/or rate at which a relatively unspecialized cell in the subpallium acquires features of a neuron. The subpallium is the base region of the telencephalon.
60166	olfactory pit development	P	The biological process whose specific outcome is the progression of the olfactory pit from an initial condition to its mature state. This process begins with the formation of the olfactory pit, which is an indentation of the olfactory placode, and ends when the pits hollows out to form the nasopharynx.
60167	regulation of adenosine receptor signaling pathway	P	Any process that modulates the frequency, rate or extent of the adenosine receptor signaling pathway. The adenosine receptor pathway is the series of molecular signals generated as a consequence of an adenosine receptor binding to one of its physiological ligands.
60168	positive regulation of adenosine receptor signaling pathway	P	Any process that activates or increases the frequency, rate or extent of the adenosine receptor signaling pathway. The adenosine receptor pathway is the series of molecular signals generated as a consequence of an adenosine receptor binding to one of its physiological ligands.
60169	negative regulation of adenosine receptor signaling pathway	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the adenosine receptor signaling pathway. The adenosine receptor pathway is the series of molecular signals generated as a consequence of an adenosine receptor binding to one of its physiological ligands.
60170	ciliary membrane	C	The portion of the plasma membrane surrounding a cilium.
60171	stereocilium membrane	C	The portion of the plasma membrane surrounding a stereocilium.
60172	astral microtubule depolymerization	P	The removal of tubulin heterodimers from one or both ends of an astral microtubule. An astral microtubule is any of the spindle microtubules that radiate in all directions from the spindle poles and are thought to contribute to the forces that separate the poles and position them in relation to the rest of the cell.
60173	limb development	P	The process whose specific outcome is the progression of a limb over time, from its formation to the mature structure. A limb is an appendage of an animal used for locomotion or grasping. Examples include legs, arms or some types of fin.
60174	limb bud formation	P	The process pertaining to the initial formation of a limb bud from unspecified parts. This process begins with the formation of a local condensation of mesenchyme cells within the prospective limb field, and ends when a limb bud is recognizable.
60175	brain-derived neurotrophic factor-activated receptor activity	F	Combining with a brain-derived neurotrophic factor and transmitting the signal across the plasma membrane to initiate a change in cell activity.
60176	regulation of aggregation involved in sorocarp development	P	Any process that modulates the frequency, rate or extent of aggregation during sorocarp development. Aggregation involved in sorocarp development is the process whose specific outcome is the progression of the aggregate over time, from its formation to the point when a slug is formed. Aggregate development begins in response to starvation and continues by the chemoattractant-mediated movement of cells toward each other. The aggregate is a multicellular structure that gives rise to the slug.
60177	regulation of angiotensin metabolic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving angiotensin.
60178	regulation of exocyst localization	P	Any process that modulates the localization of exocysts. An exocyst is a protein complex peripherally associated with the plasma membrane that determines where vesicles dock and fuse.
60179	male mating behavior	P	The specific behavior of a male organism that is associated with reproduction.
60180	female mating behavior	P	The specific behavior of a female organism that is associated with reproduction.
60182	apelin receptor activity	F	Combining with the peptide apelin to initiate a change in cell activity.
60183	apelin receptor signaling pathway	P	The series of molecular signals generated as a consequence of an apelin receptor binding to one of its physiological ligands.
60184	cell cycle switching	P	The process in which a cell switches cell cycle mode.
60185	outer ear unfolding	P	The opening and spreading out of the outer ear.
60186	outer ear emergence	P	The growth of the outer ear.
60187	cell pole	C	Either of two different areas at opposite ends of an axis of a cell.
60188	regulation of protein desumoylation	P	Any process that modulates the frequency, rate or extent of protein desumoylation. Protein desumoylation is the process in which a SUMO protein (small ubiquitin-related modifier) is cleaved from its target protein.
60189	positive regulation of protein desumoylation	P	Any process that increases the frequency, rate or extent of protein desumoylation. Protein desumoylation is the process in which a SUMO protein (small ubiquitin-related modifier) is cleaved from its target protein.
60190	negative regulation of protein desumoylation	P	Any process that decreases the frequency, rate or extent of protein desumoylation. Protein desumoylation is the process in which a SUMO protein (small ubiquitin-related modifier) is cleaved from its target protein.
60191	regulation of lipase activity	P	Any process that modulates the frequency, rate or extent of lipase activity, the hydrolysis of a lipid or phospholipid.
60192	negative regulation of lipase activity	P	Any process that decreases the frequency, rate or extent of lipase activity, the hydrolysis of a lipid or phospholipid.
60193	positive regulation of lipase activity	P	Any process that increases the frequency, rate or extent of lipase activity, the hydrolysis of a lipid or phospholipid.
60194	regulation of antisense RNA transcription	P	Any process that modulates the frequency, rate or extent of the synthesis of antisense RNA, an RNA molecule complementary in sequence to another RNA or DNA molecule, which, by binding the latter, acts to inhibit its function and/or completion of synthesis, on a template of DNA.
60195	negative regulation of antisense RNA transcription	P	Any process that decreases the frequency, rate or extent of the synthesis of antisense RNA, an RNA molecule complementary in sequence to another RNA or DNA molecule, which, by binding the latter, acts to inhibit its function and/or completion of synthesis, on a template of DNA.
60196	positive regulation of antisense RNA transcription	P	Any process that increases the frequency, rate or extent of the synthesis of antisense RNA, an RNA molecule complementary in sequence to another RNA or DNA molecule, which, by binding the latter, acts to inhibit its function and/or completion of synthesis, on a template of DNA.
60197	cloacal septation	P	The separation of the single opening of the digestive, urinary, and reproductive tracts, the cloaca, into multiple isolated openings during development.
60198	clathrin-sculpted vesicle	C	A clathrin-sculpted lipid bilayer membrane-enclosed vesicle after clathrin release.
60199	clathrin-sculpted glutamate transport vesicle	C	A clathrin-sculpted lipid bilayer membrane-enclosed vesicle after clathrin release and containing glutamate.
60200	clathrin-sculpted acetylcholine transport vesicle	C	A clathrin-sculpted lipid bilayer membrane-enclosed vesicle after clathrin release and containing acetylcholine.
60201	clathrin-sculpted acetylcholine transport vesicle membrane	C	The lipid bilayer surrounding a clathrin-sculpted acetylcholine transport vesicle.
60202	clathrin-sculpted acetylcholine transport vesicle lumen	C	The volume enclosed by the membrane of the clathrin-sculpted acetylcholine transport vesicle.
60203	clathrin-sculpted glutamate transport vesicle membrane	C	The lipid bilayer surrounding a clathrin-sculpted glutamate transport vesicle.
60204	clathrin-sculpted glutamate transport vesicle lumen	C	The volume enclosed by the membrane of the clathrin-sculpted glutamate transport vesicle.
60205	cytoplasmic vesicle lumen	C	The volume enclosed by a cytoplasmic vesicle.
60206	estrous cycle phase	P	The progression of physiological phases, occurring in the endometrium during the estrous cycle that recur at regular intervals during the reproductive years. The estrous cycle is an ovulation cycle where the endometrium is resorbed if pregnancy does not occur.
60207	diestrus	P	The estrous cycle phase which is a period of sexual quiescence and represents the phase of the mature corpus luteum.
60208	proestrus	P	The estrous cycle phase in which there is heightened follicular activity.
60209	estrus	P	The estrous cycle phase in which a female is sexually receptive.
60210	metestrus	P	The estrous cycle phase in which there is subsiding follicular function.
60211	regulation of nuclear-transcribed mRNA poly(A) tail shortening	P	Any process that modulates the frequency, rate or extent of poly(A) tail shortening of a nuclear-transcribed mRNA. Poly(A) tail shortening is the decrease in length of the poly(A) tail of an mRNA from full length to an oligo(A) length.
60212	negative regulation of nuclear-transcribed mRNA poly(A) tail shortening	P	Any process that decreases the frequency, rate or extent of poly(A) tail shortening of a nuclear-transcribed mRNA. Poly(A) tail shortening is the decrease in length of the poly(A) tail of an mRNA from full length to an oligo(A) length.
60213	positive regulation of nuclear-transcribed mRNA poly(A) tail shortening	P	Any process that increases the frequency, rate or extent of poly(A) tail shortening of a nuclear-transcribed mRNA. Poly(A) tail shortening is the decrease in length of the poly(A) tail of an mRNA from full length to an oligo(A) length.
60214	endocardium formation	P	Formation of the endocardium of the heart. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers.
60215	primitive hemopoiesis	P	A first transient wave of blood cell production that, in vertebrates, gives rise to erythrocytes (red blood cells) and myeloid cells.
60216	definitive hemopoiesis	P	A second wave of blood cell production that, in vertebrates, generates long-term hemopoietic stem cells that continously provide erythroid, myeloid and lymphoid lineages throughout adulthood.
60217	hemangioblast cell differentiation	P	The process in which a relatively unspecialized cell acquires the characteristics of a mature hemangioblast. Hemangioblasts are the proposed common precursor of blood and endothelial lineages.
60218	hematopoietic stem cell differentiation	P	The process in which a relatively unspecialized cell acquires specialized features of a hematopoietic stem cell. A stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells.
60219	camera-type eye photoreceptor cell differentiation	P	The process in which a relatively unspecialized cell acquires the specialized features of a photoreceptor cell in a camera-type eye.
60220	camera-type eye photoreceptor cell fate commitment	P	The process in which the developmental fate of a cell becomes restricted such that it will develop into a photoreceptor cell in a camera-type eye.
60221	retinal rod cell differentiation	P	The process in which a relatively unspecialized cell acquires the specialized features of a retinal rod cell.
60222	regulation of retinal cone cell fate commitment	P	Any process that modulates the process in which a cell becomes committed to a retinal cone cell fate. Retinal cone cell fate commitment is the process in which the developmental fate of a cell becomes restricted such that it will develop into a retinal cone cell.
60223	retinal rod cell fate commitment	P	The process in which the developmental fate of a cell becomes restricted such that it will develop into a retinal rod cell. A retinal rod cell is one of the two photoreceptor subtypes in a camera-type eye.
60224	regulation of retinal rod cell fate commitment	P	Any process that modulates the process in which the developmental fate of a cell becomes restricted such that it will develop into a retinal rod cell. A retinal rod cell is one of the two photoreceptor subtypes in a camera-type eye.
60225	positive regulation of retinal rod cell fate commitment	P	Any process that increases the process in which the developmental fate of a cell becomes restricted such that it will develop into a retinal rod cell. A retinal rod cell is one of the two photoreceptor subtypes in a camera-type eye.
60226	negative regulation of retinal cone cell fate commitment	P	Any process that increases the process in which a cell becomes committed to a retinal cone cell fate. Retinal cone cell fate commitment is the process in which the developmental fate of a cell becomes restricted such that it will develop into a retinal cone cell.
60227	Notch signaling pathway involved in camera-type eye photoreceptor fate commitment	P	The series of molecular signals initiated by binding of an extracellular ligand to a Notch receptor on the surface of the target cell that contributes to the commitment of a precursor cell to a eye photoreceptor fate.
60228	phosphatidylcholine-sterol O-acyltransferase activator activity	F	Increases the activity of phosphatidylcholine-sterol O-acyltransferase, an enzyme that converts cholesterol and phosphatidylcholine (lecithins) to cholesteryl esters and lyso-phosphatidylcholines.
60229	lipase activator activity	F	Binds to and increases the activity of a lipase, an enzyme that catalyzes of the hydrolysis of a lipid.
60230	lipoprotein lipase activator activity	F	Binds to and increases the activity of a lipoprotein lipase, an enzyme that catalyzes of the hydrolysis of a lipid within a lipoprotein.
60231	mesenchymal to epithelial transition	P	A transition where a mesenchymal cell establishes apical/basolateral polarity, forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell.
60232	delamination	P	The process of negative regulation of cell adhesion that results in a cell or sheet of cells splitting off from an existing epithelial sheet.
60233	oenocyte delamination	P	The negative regulation of cell adhesion process in which an oenocyte splits off of an existing epithelial sheet.
60234	neuroblast delamination	P	The negative regulation of cell adhesion process in which a neuroblast splits off of a neurectodermal sheet.
60235	lens induction in camera-type eye	P	Signaling at short range between the head ectoderm and the optic vesicle that results in the head ectoderm forming a lens.
60236	regulation of mitotic spindle organization	P	Any process that modulates the rate, frequency or extent of the assembly, arrangement of constituent parts, or disassembly of the microtubule spindle during a mitotic cell cycle.
60237	regulation of fungal-type cell wall organization	P	Any process that modulates the rate, frequency or extent of the formation, arrangement of constituent parts, or disassembly of the fungal-type cell wall.
60238	regulation of signal transduction involved in conjugation with cellular fusion	P	Any process that modulates the rate, frequency or extent of pheromone-dependent signal transduction during conjugation with cellular fusion, the series of molecular signals that bring about the relay, amplification or dampening of a signal generated in response to a cue, such as starvation or pheromone exposure, in organisms that undergo conjugation with cellular fusion.
60239	positive regulation of signal transduction involved in conjugation with cellular fusion	P	Any process that increases the rate, frequency or extent of the series of molecular signals that bring about the relay, amplification or dampening of a signal generated in response to a cue, such as starvation or pheromone exposure, in organisms that undergo conjugation with cellular fusion.
60240	negative regulation of signal transduction involved in conjugation with cellular fusion	P	Any process that decreases the rate, frequency or extent of the series of molecular signals that bring about the relay, amplification or dampening of a signal generated in response to a cue, such as starvation or pheromone exposure, in organisms that undergo conjugation with cellular fusion.
60241	lysozyme inhibitor activity	F	Stops, prevents or reduces the activity of a lysozyme, an enzyme that hydrolyses the beta- (1,4) glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine in peptidoglycan.
60242	contact inhibition	P	The cellular process in which cells stop growing or dividing in response to increased cell density.
60243	negative regulation of cell growth involved in contact inhibition	P	The negative regulation of cell growth in response to increased cell density.
60244	negative regulation of cell proliferation involved in contact inhibition	P	Any process that stops, prevents or reduces the rate or extent of cell proliferation in response to cell density.
60245	detection of cell density	P	The series of events in which information about the density of cells in a population is received and converted into a molecular signal.
60246	detection of cell density by contact stimulus	P	The series of events in which information about the density of cells in a population is received by direct cell-cell contact and is converted into a molecular signal.
60247	detection of cell density by secreted molecule	P	The series of events in which information about the density of cells in a population is received by the detection of a secreted molecule and is converted into a molecular signal.
60248	detection of cell density by contact stimulus involved in contact inhibition	P	The series of events in which information about the density of cells in a population is received by direct cell-cell contact and is converted into a molecular signal, resulting in the cessation of cell growth or proliferation.
60249	anatomical structure homeostasis	P	A homeostatic process involved in the maintenance of an internal steady state within a defined anatomical structure of an organism, including control of cellular proliferation and death and control of metabolic function. An anatomical structure is any biological entity that occupies space and is distinguished from its surroundings. Anatomical structures can be macroscopic such as a carpel, or microscopic such as an acrosome.
60250	germ-line stem-cell niche homeostasis	P	A homeostatic process involved in the maintenance of an internal steady state within the germ-line stem-cell niche. This includes control of cellular proliferation and death and control of metabolic function that allows the niche to continue to function. A gem-line stem-cell niche is an anatomical structure that regulates how germ-line stem-cells are used and saves them from depletion.
60251	regulation of glial cell proliferation	P	Any process that modulates the frequency, rate or extent of glial cell proliferation.
60252	positive regulation of glial cell proliferation	P	Any process that activates or increases the rate or extent of glial cell proliferation.
60253	negative regulation of glial cell proliferation	P	Any process that stops or decreases the rate or extent of glial cell proliferation.
60254	regulation of N-terminal protein palmitoylation	P	Any process that modulates the rate frequency or extent of the covalent attachment of a palmitoyl group to the N-terminal amino acid residue of a protein.
60255	regulation of macromolecule metabolic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving macromolecules, any molecule of high relative molecular mass, the structure of which essentially comprises the multiple repetition of units derived, actually or conceptually, from molecules of low relative molecular mass.
60256	regulation of flocculation	P	Any process that modulates the rate, frequency or extent of the non-sexual aggregation of single-celled organisms.
60257	negative regulation of flocculation	P	Any process that decreases the rate, frequency or extent of the non-sexual aggregation of single-celled organisms.
60258	negative regulation of filamentous growth	P	Any process that decreases the frequency, rate or extent of the process in which a multicellular organism or a group of unicellular organisms grow in a threadlike, filamentous shape.
60259	regulation of feeding behavior	P	Any process that modulates the rate, frequency or extent of the behavior associated with the intake of food.
60260	regulation of transcription initiation from RNA polymerase II promoter	P	Any process that modulates the rate, frequency or extent of a process involved in starting transcription from an RNA polymerase II promoter.
60261	positive regulation of transcription initiation from RNA polymerase II promoter	P	Any process that increases the rate, frequency or extent of a process involved in starting transcription from an RNA polymerase II promoter.
60262	negative regulation of N-terminal protein palmitoylation	P	Any process that decreases the rate frequency or extent of the covalent attachment of a palmitoyl group to the N-terminal amino acid residue of a protein.
60263	regulation of respiratory burst	P	Any process that modulates the rate frequency or extent of a phase of elevated metabolic activity, during which oxygen consumption increases; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals.
60264	regulation of respiratory burst involved in inflammatory response	P	Any process that modulates the rate, frequency or extent of a phase of elevated metabolic activity, during which oxygen consumption increases made as a defense response; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals.
60265	positive regulation of respiratory burst involved in inflammatory response	P	Any process that increases the rate, frequency or extent of a phase of elevated metabolic activity, during which oxygen consumption increases made as a defense response; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals.
60266	negative regulation of respiratory burst involved in inflammatory response	P	Any process that decreases the rate, frequency or extent of a phase of elevated metabolic activity, during which oxygen consumption increases made as a defense response; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals.
60267	positive regulation of respiratory burst	P	Any process that increases the rate frequency or extent of a phase of elevated metabolic activity, during which oxygen consumption increases; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals.
60268	negative regulation of respiratory burst	P	Any process that decreases the rate frequency or extent of a phase of elevated metabolic activity, during which oxygen consumption increases; this leads to the production, by an NADH dependent system, of hydrogen peroxide (H2O2), superoxide anions and hydroxyl radicals.
60269	centripetally migrating follicle cell migration	P	The cell migration process in which a follicle cell migrates as part of an epithelial sheet between the nurse cells and the oocyte. At the end of migration, they cover the anterior of the oocyte.
60270	main body follicle cell migration	P	The ovarian follicle cell migration process in which follicle cells migrate posteriorly to form a columnar epithelium over the oocyte.
60271	cilium assembly	P	The assembly of a cilium, a specialized eukaryotic organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole.
60272	embryonic skeletal joint morphogenesis	P	The process in which the anatomical structures of skeletal joints are generated and organized during the embryonic phase. A skeletal joint is the connecting structure between the bones of the skeleton.
60273	crying behavior	P	The behavior in which an organism sheds tears, often accompanied by non-verbal vocalizations and in response to external or internal stimuli.
60274	maintenance of stationary phase	P	The homeostatic process in which a population of cells changes its metabolic activity resulting in the rate of death in the population equaling the rate of reproduction. Stationary phase can be in response to limited nutrients or a build-up of toxic substances in the environment.
60275	maintenance of stationary phase in response to starvation	P	The homeostatic process in which a population of cells changes its metabolic activity resulting in the rate of death in the population equaling the rate of reproduction in response to limited nutrients in the environment.
60276	maintenance of stationary phase in response to toxin	P	The homeostatic process in which a population of cells changes its metabolic activity resulting in the rate of death in the population equaling the rate of reproduction in response to a build-up of toxins in the environment.
60278	regulation of ovulation	P	Any process that modulates the frequency, rate or extent of ovulation, the release of a mature ovum/oocyte from an ovary.
60279	positive regulation of ovulation	P	Any process that activates or increases the frequency, rate or extent of ovulation, the release of a mature ovum/oocyte from an ovary.
60280	negative regulation of ovulation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of ovulation, the release of a mature ovum/oocyte from an ovary.
60281	regulation of oocyte development	P	Any process that modulates the rate or extent of the process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell.
60282	positive regulation of oocyte development	P	Any process that increases the rate or extent of the process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell.
60283	negative regulation of oocyte development	P	Any process that decreases the rate or extent of the process whose specific outcome is the progression of an oocyte over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell.
60284	regulation of cell development	P	Any process that modulates the rate, frequency or extent of the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate.
60285	cilium-dependent cell motility	P	Cell motility due to the motion of one or more eukaryotic cilia. A eukaryotic cilium is a specialized organelle that consists of a filiform extrusion of the cell surface. Each cilium is bounded by an extrusion of the cytoplasmic (plasma) membrane, and contains a regular longitudinal array of microtubules, anchored basally in a centriole.
60287	epithelial cilium movement involved in determination of left/right asymmetry	P	The movement of cilia of epithelial cells resulting in the transport of signals which determine asymmetry in an organism's body plan with respect to the left and right halves.
60288	formation of a compartment boundary	P	Formation of a lineage restriction boundary within a developing tissue which does not correspond to some morphological barrier.
60289	compartment boundary maintenance	P	A homeostatic process involved in the maintenance of a compartment boundary. A compartment boundary is a lineage restriction boundary within a developing tissue which does not correspond to some morphological barrier.
60290	transdifferentiation	P	The conversion of a differentiated cell of one fate into a differentiated cell of another fate without first undergoing cell division or reversion to a more primitive or stem cell-like fate.
60291	long-term synaptic potentiation	P	A process that modulates synaptic plasticity such that synapses are changed resulting in the increase in the rate, or frequency of synaptic transmission at the synapse.
60292	long term synaptic depression	P	A process that modulates synaptic plasticity such that synapses are changed resulting in the decrease in the rate, or frequency of synaptic transmission at the synapse.
60293	germ plasm	C	Differentiated cytoplasm associated with a pole of an oocyte, egg or early embryo that will be inherited by the cells that will give rise to the germ line.
60294	cilium movement involved in cell motility	P	Movement of cilia mediated by motor proteins that contributes to the movement of a cell.
60295	regulation of cilium movement involved in cell motility	P	Any process that modulates the rate frequency or extent of cilium movement involved in ciliary motility.
60296	regulation of cilium beat frequency involved in ciliary motility	P	Any process that modulates the frequency of cilium beating involved in ciliary motility.
60297	regulation of sarcomere organization	P	Any process that modulates the rate, frequency or extent myofibril assembly by organization of muscle actomyosin into sarcomeres. The sarcomere is the repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs.
60298	positive regulation of sarcomere organization	P	Any process that increases the rate, frequency or extent myofibril assembly by organization of muscle actomyosin into sarcomeres. The sarcomere is the repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs.
60299	negative regulation of sarcomere organization	P	Any process that decreases the rate, frequency or extent myofibril assembly by organization of muscle actomyosin into sarcomeres. The sarcomere is the repeating unit of a myofibril in a muscle cell, composed of an array of overlapping thick and thin filaments between two adjacent Z discs.
60300	regulation of cytokine activity	P	Any process that modulates the rate, frequency or extent of the activity of a molecule that controls the survival, growth, differentiation and effector function of tissues and cells.
60301	positive regulation of cytokine activity	P	Any process that increases the rate, frequency or extent of the activity of a molecule that controls the survival, growth, differentiation and effector function of tissues and cells.
60302	negative regulation of cytokine activity	P	Any process that decreases the rate, frequency or extent of the activity of a molecule that controls the survival, growth, differentiation and effector function of tissues and cells.
60303	regulation of nucleosome density	P	Any process that modulates the number of nucleosomes in a given region of a chromosome.
60304	regulation of phosphatidylinositol dephosphorylation	P	Any process that modulates the frequency, rate or extent of the chemical reaction involving the removal of one or more phosphate groups from a phosphatidylinositol.
60305	regulation of cell diameter	P	Any process that modulates the diameter of a cell, the length of a line segment that crosses through the center of a circular section through a cell.
60306	regulation of membrane repolarization	P	Any process that modulates the establishment or extent of a membrane potential in the polarizing direction towards the resting potential, usually from positive to negative.
60307	regulation of ventricular cardiac muscle cell membrane repolarization	P	Any process that modulates the establishment or extent of a membrane potential in the polarizing direction towards the resting potential in a ventricular cardiomyocyte.
60308	GTP cyclohydrolase I regulator activity	F	Modulates the activity of GTP cyclohydrolase I. GTP cyclohydrolase I activity catalyzes the reaction: GTP + 2 H2O = formate + 2-amino-4-hydroxy-6-(erythro-1,2,3-trihydroxypropyl)-dihydropteridine triphosphate.
60309	elastin catabolic process	P	The chemical reactions and pathways resulting in the breakdown of elastin. Elastin is a glycoprotein which is randomly coiled and crosslinked to form elastic fibers that are found in connective tissue.
60310	regulation of elastin catabolic process	P	Any process that modulates the rate, frequency or extent of elastin catabolism, the chemical reactions and pathways resulting in the breakdown of elastin.
60311	negative regulation of elastin catabolic process	P	Any process that decreases the rate, frequency or extent of elastin catabolism, the chemical reactions and pathways resulting in the breakdown of elastin.
60312	regulation of blood vessel remodeling	P	Any process that modulates the rate, frequency or extent of blood vessel remodeling, the reorganization or renovation of existing blood vessels.
60313	negative regulation of blood vessel remodeling	P	Any process that decreases the rate, frequency or extent of blood vessel remodeling, the reorganization or renovation of existing blood vessels.
60314	regulation of ryanodine-sensitive calcium-release channel activity	P	Any process that modulates the activity of a ryanodine-sensitive calcium-release channel. The ryanodine-sensitive calcium-release channel catalyzes the transmembrane transfer of a calcium ion by a channel that opens when a ryanodine class ligand has been bound by the channel complex or one of its constituent parts.
60315	negative regulation of ryanodine-sensitive calcium-release channel activity	P	Any process that decreases the activity of a ryanodine-sensitive calcium-release channel. The ryanodine-sensitive calcium-release channel catalyzes the transmembrane transfer of a calcium ion by a channel that opens when a ryanodine class ligand has been bound by the channel complex or one of its constituent parts.
60316	positive regulation of ryanodine-sensitive calcium-release channel activity	P	Any process that increases the activity of a ryanodine-sensitive calcium-release channel. The ryanodine-sensitive calcium-release channel catalyzes the transmembrane transfer of a calcium ion by a channel that opens when a ryanodine class ligand has been bound by the channel complex or one of its constituent parts.
60317	cardiac epithelial to mesenchymal transition	P	A transition where a cardiac epithelial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell.
60318	definitive erythrocyte differentiation	P	Erythrocyte differentiation which occurs as part of the process of definitive hemopoiesis.
60319	primitive erythrocyte differentiation	P	Erythrocyte differentiation which occurs as part of the process of primitive hemopoiesis.
60320	rejection of self pollen	P	The process, involving the sharing and interaction of the single locus incompatibility haplotypes, involved in the rejection of the self pollen by cells in the stigma.
60321	acceptance of pollen	P	The process, involving the sharing and interaction of the single locus incompatibility haplotypes, involved in the acceptance of pollen by cells in the stigma.
60322	head development	P	The biological process whose specific outcome is the progression of a head from an initial condition to its mature state. The head is the anterior-most division of the body.
60323	head morphogenesis	P	The process in which the anatomical structures of the head are generated and organized. The head is the anterior-most division of the body.
60324	face development	P	The biological process whose specific outcome is the progression of a face from an initial condition to its mature state. The face is the ventral division of the head.
60325	face morphogenesis	P	The process in which the anatomical structures of the face are generated and organized. The face is the ventral division of the head.
60326	cell chemotaxis	P	The directed movement of a motile cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis).
60327	cytoplasmic actin-based contraction involved in cell motility	P	The actin filament-based movement by which cytoplasmic actin filaments slide past one another resulting in a contraction that propels the cell from one place to another.
60328	cytoplasmic actin-based contraction involved in forward cell motility	P	The actin filament-based movement by which cytoplasmic actin filaments slide past one another resulting in a contraction that propels the cell in the direction that has been defined as the front of the cell.
60329	cytoplasmic actin-based contraction involved in rearward cell motility	P	The actin filament-based movement by which cytoplasmic actin filaments slide past one another resulting in a contraction that propels the cell in the direction that has been defined as the rear of the cell.
60330	regulation of response to interferon-gamma	P	Any process that modulates the rate, frequency or extent of a response to interferon-gamma. Response to interferon gamma is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-gamma stimulus.
60331	negative regulation of response to interferon-gamma	P	Any process that decreases the rate, frequency or extent of a response to interferon-gamma. Response to interferon gamma is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-gamma stimulus.
60332	positive regulation of response to interferon-gamma	P	Any process that increases the rate, frequency or extent of a response to interferon-gamma. Response to interferon gamma is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-gamma stimulus.
60333	interferon-gamma-mediated signaling pathway	P	A series of molecular signals initiated by the binding of interferon-gamma to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. Interferon gamma is the only member of the type II interferon found so far.
60334	regulation of interferon-gamma-mediated signaling pathway	P	Any process that modulates the rate, frequency or extent of the series of molecular events generated as a consequence of interferon-gamma binding to a cell surface receptor.
60335	positive regulation of interferon-gamma-mediated signaling pathway	P	Any process that increases the rate, frequency or extent of the series of molecular events generated as a consequence of interferon-gamma binding to a cell surface receptor.
60336	negative regulation of interferon-gamma-mediated signaling pathway	P	Any process that decreases the rate, frequency or extent of the series of molecular events generated as a consequence of interferon-gamma binding to a cell surface receptor.
60337	type I interferon signaling pathway	P	A series of molecular signals initiated by the binding of a type I interferon to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families.
60338	regulation of type I interferon-mediated signaling pathway	P	Any process that modulates the rate, frequency or extent of a type I interferon-mediated signaling pathway. A type I interferon-mediated signaling pathway is the series of molecular events generated as a consequence of a type I interferon binding to a cell surface receptor.
60339	negative regulation of type I interferon-mediated signaling pathway	P	Any process that decreases the rate, frequency or extent of a type I interferon-mediated signaling pathway. A type I interferon-mediated signaling pathway is the series of molecular events generated as a consequence of a type I interferon binding to a cell surface receptor.
60340	positive regulation of type I interferon-mediated signaling pathway	P	Any process that increases the rate, frequency or extent of a type I interferon-mediated signaling pathway. A type I interferon-mediated signaling pathway is the series of molecular events generated as a consequence of a type I interferon binding to a cell surface receptor.
60341	regulation of cellular localization	P	Any process that modulates the frequency, rate or extent of a process in which a cell, a substance, or a cellular entity is transported to, or maintained in a specific location within or in the membrane of a cell.
60342	photoreceptor inner segment membrane	C	The membrane surrounding the inner segment of a vertebrate photoreceptor. The photoreceptor inner segment contains mitochondria, ribosomes and membranes where opsin molecules are assembled and passed to be part of the outer segment discs.
60343	trabecula formation	P	The process of creating a trabecula in an organ. A trabecula is a small, often microscopic, tissue element in the form of a small beam, strut or rod, which generally has a mechanical function. Trabecula are usually but not necessarily, composed of dense collagenous tissue.
60344	liver trabecula formation	P	The process of creating a trabecula in the liver. A trabecula is a tissue element in the form of a small beam, strut or rod.
60345	spleen trabecula formation	P	The process of creating a trabecula in the spleen. A trabecula is a tissue element in the form of a small beam, strut or rod.
60346	bone trabecula formation	P	The process of creating a trabecula in the bone. A trabecula is a tissue element in the form of a small beam, strut or rod.
60347	heart trabecula formation	P	The process of creating a trabecula in the heart. A trabecula is a tissue element in the form of a small beam, strut or rod.
60348	bone development	P	The process whose specific outcome is the progression of bone over time, from its formation to the mature structure. Bone is the hard skeletal connective tissue consisting of both mineral and cellular components.
60349	bone morphogenesis	P	The process in which bones are generated and organized.
60350	endochondral bone morphogenesis	P	The process in which bones are generated and organized as a result of the conversion of initial cartilaginous anlage into bone.
60351	cartilage development involved in endochondral bone morphogenesis	P	The process whose specific outcome is the progression of the cartilage that will provide a scaffold for mineralization of endochondral bones.
60352	cell adhesion molecule production	P	The appearance of a cell adhesion molecule due to biosynthesis or secretion.
60353	regulation of cell adhesion molecule production	P	Any process that modulates the rate, frequency or extent of cell adhesion molecule production. Cell adhesion molecule production is the appearance of a cell adhesion molecule as a result of its biosynthesis or a decrease in its catabolism.
60354	negative regulation of cell adhesion molecule production	P	Any process that decreases the rate, frequency or extent of cell adhesion molecule production. Cell adhesion molecule production is the appearance of a cell adhesion molecule as a result of its biosynthesis or a decrease in its catabolism.
60355	positive regulation of cell adhesion molecule production	P	Any process that increases the rate, frequency or extent of cell adhesion molecule production. Cell adhesion molecule production is the appearance of a cell adhesion molecule as a result of its biosynthesis or a decrease in its catabolism.
60356	leucine import	P	The directed movement of leucine into a cell or organelle.
60357	regulation of leucine import	P	Any process that modulates the rate, frequency or extent of leucine import. Leucine import is the directed movement of leucine into a cell or organelle.
60358	negative regulation of leucine import	P	Any process that decreases the rate, frequency or extent of leucine import. Leucine import is the directed movement of leucine into a cell or organelle.
60359	response to ammonium ion	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ammonium ion stimulus.
60360	negative regulation of leucine import in response to ammonium ion	P	Any process that decreases the rate, frequency or extent of leucine import as a result of an ammonium ion stimulus. Leucine import is the directed movement of leucine into a cell or organelle.
60361	flight	P	Self-propelled movement of an organism from one location to another through the air, usually by means of active wing movement.
60362	flight involved in flight behavior	P	Self-propelled movement of an organism from one location to another through the air that is part of the organism's response to external or internal stimuli resulting in flight.
60363	cranial suture morphogenesis	P	The process in which any suture between cranial bones is generated and organized.
60364	frontal suture morphogenesis	P	The process in which the frontal suture is generated and organized.
60365	coronal suture morphogenesis	P	The process in which the coronal suture is generated and organized.
60366	lambdoid suture morphogenesis	P	The process in which the lambdoid suture is generated and organized.
60367	sagittal suture morphogenesis	P	The process in which the sagittal suture is generated and organized.
60368	regulation of Fc receptor mediated stimulatory signaling pathway	P	Any process that modulates the rate, frequency or extent of the Fc receptor mediated stimulatory signaling pathway. The Fc receptor mediated stimulatory signaling pathway is a series of molecular signals generated as a consequence of a the binding of the Fc portion of an immunoglobulin by an Fc receptor capable of activating or perpetuating an immune response. The Fc portion of an immunoglobulin is its C-terminal constant region.
60369	positive regulation of Fc receptor mediated stimulatory signaling pathway	P	Any process that increases the rate, frequency or extent of the Fc receptor mediated stimulatory signaling pathway. The Fc receptor mediated stimulatory signaling pathway is a series of molecular signals generated as a consequence of a the binding of the Fc portion of an immunoglobulin by an Fc receptor capable of activating or perpetuating an immune response. The Fc portion of an immunoglobulin is its C-terminal constant region.
60370	susceptibility to T cell mediated cytotoxicity	P	The process of causing a cell to become susceptible to T cell mediated cytotoxicity.
60371	regulation of atrial cardiac muscle cell membrane depolarization	P	Any process that modulates the establishment or extent of a membrane potential in the depolarizing direction away from the resting potential in an atrial cardiomyocyte.
60372	regulation of atrial cardiac muscle cell membrane repolarization	P	Any process that modulates the establishment or extent of a membrane potential in the polarizing direction towards the resting potential in an atrial cardiomyocyte.
60373	regulation of ventricular cardiac muscle cell membrane depolarization	P	Any process that modulates the establishment or extent of a membrane potential in the depolarizing direction away from the resting potential in a ventricular cardiomyocyte.
60374	mast cell differentiation	P	The process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of a mast cell. A mast cell is a cell that is found in almost all tissues containing numerous basophilic granules and capable of releasing large amounts of histamine and heparin upon activation.
60375	regulation of mast cell differentiation	P	Any process that modulates the rate, frequency or extent of mast cell differentiation, the process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of a mast cell. A mast cell is a cell that is found in almost all tissues containing numerous basophilic granules and capable of releasing large amounts of histamine and heparin upon activation.
60376	positive regulation of mast cell differentiation	P	Any process that increases the rate, frequency or extent of mast cell differentiation, the process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of a mast cell. A mast cell is a cell that is found in almost all tissues containing numerous basophilic granules and capable of releasing large amounts of histamine and heparin upon activation.
60377	negative regulation of mast cell differentiation	P	Any process that decreases the rate, frequency or extent of mast cell differentiation, the process in which a relatively unspecialized myeloid precursor cell acquires the specialized features of a mast cell. A mast cell is a cell that is found in almost all tissues containing numerous basophilic granules and capable of releasing large amounts of histamine and heparin upon activation.
60378	regulation of brood size	P	Any process that modulates brood size. Brood size is the number of progeny that survive embryogenesis and are cared for at one time.
60379	cardiac muscle cell myoblast differentiation	P	The process in which a relatively unspecialized cell acquires specialized features of a cardiac myoblast. A cardiac myoblast is a precursor cell that has been committed to a cardiac muscle cell fate but retains the ability to divide and proliferate throughout life.
60380	regulation of single-stranded telomeric DNA binding	P	Any process that modulates the frequency, rate or extent of binding to single-stranded telomeric DNA.
60381	positive regulation of single-stranded telomeric DNA binding	P	Any process that increases the frequency, rate or extent of single-stranded telomeric DNA binding.
60382	regulation of DNA strand elongation	P	Any process that modulates the rate, frequency or extent of DNA strand elongation. DNA strand elongation is the DNA metabolic process in which a DNA strand is synthesized by adding nucleotides to the 3' end of an existing DNA stand.
60383	positive regulation of DNA strand elongation	P	Any process that increases the rate, frequency or extent of DNA strand elongation. DNA strand elongation is the DNA metabolic process in which a DNA strand is synthesized by adding nucleotides to the 3' end of an existing DNA stand.
60384	innervation	P	The process in which a nerve invades a tissue and makes functional synaptic connection within the tissue.
60385	axonogenesis involved in innervation	P	The neurite development process that generates a long process of a neuron, as it invades a target tissue.
60386	synapse assembly involved in innervation	P	The assembly of a synapse within a target tissue in which a nerve is invading.
60387	fertilization envelope	C	A structure that lies outside the plasma membrane and surrounds the egg. The fertilization envelope forms from the vitelline membrane after fertilization as a result of cortical granule release.
60388	vitelline envelope	C	A glycoprotein-based structure that lies outside the plasma membrane and surrounds the egg before fertilization.
60389	pathway-restricted SMAD protein phosphorylation	P	The process of introducing a phosphate group on to a pathway restricted SMAD protein. A pathway restricted SMAD protein is an effector protein that acts directly downstream of the transforming growth factor family receptor.
60390	regulation of SMAD protein import into nucleus	P	Any process that modulates the rate, frequency or extent of SMAD protein import into the nucleus, i.e. the directed movement of a SMAD proteins from the cytoplasm into the nucleus. Pathway-restricted SMAD proteins and common-partner SMAD proteins are involved in the transforming growth factor beta receptor signaling pathways.
60391	positive regulation of SMAD protein import into nucleus	P	Any process that increases the rate, frequency or extent of SMAD protein import into the nucleus, i.e. the directed movement of a SMAD proteins from the cytoplasm into the nucleus. Pathway-restricted SMAD proteins and common-partner SMAD proteins are involved in the transforming growth factor beta receptor signaling pathways.
60392	negative regulation of SMAD protein import into nucleus	P	Any process that decreases the rate, frequency or extent of SMAD protein import into the nucleus, i.e. the directed movement of a SMAD proteins from the cytoplasm into the nucleus. Pathway-restricted SMAD proteins and common-partner SMAD proteins are involved in the transforming growth factor beta receptor signaling pathways.
60393	regulation of pathway-restricted SMAD protein phosphorylation	P	Any process that modulates the rate, frequency or extent of pathway-restricted SMAD protein phosphorylation. Pathway-restricted SMAD proteins and common-partner SMAD proteins are involved in the transforming growth factor beta receptor signaling pathways.
60394	negative regulation of pathway-restricted SMAD protein phosphorylation	P	Any process that decreases the rate, frequency or extent of pathway-restricted SMAD protein phosphorylation. Pathway-restricted SMAD proteins and common-partner SMAD proteins are involved in the transforming growth factor beta receptor signaling pathways.
60395	SMAD protein signal transduction	P	The cascade of processes by which a signal interacts with a receptor, causing a change in the activity of a SMAD protein, and ultimately effecting a change in the functioning of the cell.
60396	growth hormone receptor signaling pathway	P	The series of molecular signals generated as a consequence of growth hormone receptor binding to its physiological ligand.
60397	JAK-STAT cascade involved in growth hormone signaling pathway	P	The process in which STAT proteins (Signal Transducers and Activators of Transcription) are activated by members of the JAK (janus activated kinase) family of tyrosine kinases, following the binding of physiological ligands to the growth hormone receptor. Once activated, STATs dimerize and translocate to the nucleus and modulate the expression of target genes.
60398	regulation of growth hormone receptor signaling pathway	P	Any process that modulates the rate, frequency or extent of the growth hormone receptor signaling pathway. The growth hormone receptor signaling pathway is the series of molecular signals generated as a consequence of growth hormone receptor binding to its physiological ligand.
60399	positive regulation of growth hormone receptor signaling pathway	P	Any process that increases the rate, frequency or extent of the growth hormone receptor signaling pathway. The growth hormone receptor signaling pathway is the series of molecular signals generated as a consequence of growth hormone receptor binding to its physiological ligand.
60400	negative regulation of growth hormone receptor signaling pathway	P	Any process that decreases the rate, frequency or extent of the growth hormone receptor signaling pathway. The growth hormone receptor signaling pathway is the series of molecular signals generated as a consequence of growth hormone receptor binding to its physiological ligand.
60401	cytosolic calcium ion transport	P	The directed movement of calcium ions (Ca2+) into, out of or within the cytosol.
60402	calcium ion transport into cytosol	P	The directed movement of calcium ions (Ca2+) into the cytosol.
60403	post-mating oviposition	P	The deposition of eggs, either fertilized or not, upon a surface or into a medium, following mating.
60404	axonemal microtubule depolymerization	P	The removal of tubulin heterodimers from one or both ends of an axonemal microtubule. An axonemal microtubule is a microtubule in the axoneme of a cilium or flagellum; an axoneme contains nine modified doublet microtubules surrounding a pair of single microtubules.
60405	regulation of penile erection	P	Any process that modulates the rate, frequency or extent of penile erection. Penile erection is the hardening, enlarging and rising of the penis which often occurs in the sexually aroused male and enables sexual intercourse. Achieved by increased inflow of blood into the vessels of erectile tissue, and decreased outflow.
60406	positive regulation of penile erection	P	Any process that increases the rate, frequency or extent of penile erection. Penile erection is the hardening, enlarging and rising of the penis which often occurs in the sexually aroused male and enables sexual intercourse. Achieved by increased inflow of blood into the vessels of erectile tissue, and decreased outflow.
60407	negative regulation of penile erection	P	Any process that stops, prevents, or reduces the rate, frequency or extent of penile erection. Penile erection is the hardening, enlarging and rising of the penis which often occurs in the sexually aroused male and enables sexual intercourse. Achieved by increased inflow of blood into the vessels of erectile tissue, and decreased outflow.
60408	regulation of acetylcholine metabolic process	P	Any process that modulates the rate, frequency or extent of the chemical reactions and pathways involving acetylcholine, the acetic acid ester of the organic base choline. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues.
60409	positive regulation of acetylcholine metabolic process	P	Any process that increases the rate, frequency or extent of the chemical reactions and pathways involving acetylcholine, the acetic acid ester of the organic base choline. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues.
60410	negative regulation of acetylcholine metabolic process	P	Any process that decreases the rate, frequency or extent of the chemical reactions and pathways involving acetylcholine, the acetic acid ester of the organic base choline. Acetylcholine is a major neurotransmitter and neuromodulator both in the central and peripheral nervous systems. It also acts as a paracrine signal in various non-neural tissues.
60411	cardiac septum morphogenesis	P	The process in which the anatomical structure of a cardiac septum is generated and organized. A cardiac septum is a partition that separates parts of the heart.
60412	ventricular septum morphogenesis	P	The developmental process in which a ventricular septum is generated and organized. A ventricular septum is an anatomical structure that separates the lower chambers (ventricles) of the heart from one another.
60413	atrial septum morphogenesis	P	The developmental process in which atrial septum is generated and organized. The atrial septum separates the upper chambers (the atria) of the heart from one another.
60414	aorta smooth muscle tissue morphogenesis	P	The process in which the structure of the smooth muscle tissue surrounding the aorta is generated and organized. An aorta is an artery that carries blood from the heart to other parts of the body.
60415	muscle tissue morphogenesis	P	The process in which the anatomical structures of muscle tissue are generated and organized. Muscle tissue consists of a set of cells that are part of an organ and carry out a contractive function.
60416	response to growth hormone	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a growth hormone stimulus. Growth hormone is a peptide hormone that binds to the growth hormone receptor and stimulates growth.
60417	yolk	C	The cytoplasmic part that serves as a nutrient reserve or energy source for the developing embryo.
60418	yolk plasma	C	Discrete structures that partition the water-soluble portion of the yolk of oocytes and ova, which may or may not be membrane enclosed.
60419	heart growth	P	The increase in size or mass of the heart.
60420	regulation of heart growth	P	Any process that modulates the rate or extent of heart growth. Heart growth is the increase in size or mass of the heart.
60421	positive regulation of heart growth	P	Any process that increases the rate or extent of heart growth. Heart growth is the increase in size or mass of the heart.
60422	peptidyl-dipeptidase inhibitor activity	F	Stops, prevents or reduces the activity of a peptidyl-dipeptidase. Peptidyl-dipeptidase activity catalyzes the release of C-terminal dipeptides from a polypeptide chain.
60423	foregut regionalization	P	The pattern specification process that results in the spatial subdivision of an axis or axes along the foregut to define an area or volume in which specific patterns of cell differentiation will take place.
60424	lung field specification	P	The process that results in the delineation of a specific region of the foregut into the area in which the lung will develop.
60425	lung morphogenesis	P	The process in which the anatomical structures of the lung are generated and organized.
60426	lung vasculature development	P	The biological process whose specific outcome is the progression of a lung vasculature from an initial condition to its mature state. This process begins with the formation of the lung vasculature and ends with the mature structure. The lung vasculature is composed of the tubule structures that carry blood or lymph in the lungs.
60427	lung connective tissue development	P	The biological process whose specific outcome is the progression of lung connective tissue from an initial condition to its mature state. This process begins with the formation of lung connective tissue and ends with the mature structure. The lung connective tissue is a material made up of fibers forming a framework and support structure for the lungs.
60428	lung epithelium development	P	The biological process whose specific outcome is the progression of the lung epithelium from an initial condition to its mature state. This process begins with the formation of lung epithelium and ends with the mature structure. The lung epithelium is the specialized epithelium that lines the inside of the lung.
60429	epithelium development	P	The process whose specific outcome is the progression of an epithelium over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure.
60430	lung saccule development	P	The biological process whose specific outcome is the progression of a lung saccule from an initial condition to its mature state. The lung saccule is the primitive gas exchange portion of the lung composed of type I and type II cells.
60431	primary lung bud formation	P	The morphogenetic process in which the foregut region specified to become the lung forms the initial left and right buds.
60432	lung pattern specification process	P	Any developmental process that results in the creation of defined areas or spaces within the lung, to which cells respond and eventually are instructed to differentiate.
60433	bronchus development	P	The biological process whose specific outcome is the progression of a bronchus from an initial condition to its mature state. This process begins with the formation of the bronchus and ends with the mature structure. The bronchus is the portion of the airway that connects to the lungs.
60434	bronchus morphogenesis	P	The process in which the bronchus is generated and organized. The bronchus is the portion of the airway that connects to the lungs.
60435	bronchiole development	P	The biological process whose specific outcome is the progression of a bronchiole from an initial condition to its mature state. This process begins with the formation of the bronchiole and ends with the mature structure. A bronchiole is the first airway branch that no longer contains cartilage; it is a branch of the bronchi.
60436	bronchiole morphogenesis	P	The process in which a bronchiole is generated and organized. A bronchiole is the first airway branch that no longer contains cartilage; it is a branch of the bronchi.
60437	lung growth	P	The increase in size or mass of a lung. In all air-breathing vertebrates the lungs are developed from the ventral wall of the oesophagus as a pouch which divides into two sacs. In amphibians and many reptiles the lungs retain very nearly this primitive sac-like character, but in the higher forms the connection with the esophagus becomes elongated into the windpipe and the inner walls of the sacs become more and more divided, until, in the mammals, the air spaces become minutely divided into tubes ending in small air cells, in the walls of which the blood circulates in a fine network of capillaries. In mammals the lungs are more or less divided into lobes, and each lung occupies a separate cavity in the thorax.
60438	trachea development	P	The process whose specific outcome is the progression of a trachea over time, from its formation to the mature structure. The trachea is the portion of the airway that attaches to the bronchi as it branches.
60439	trachea morphogenesis	P	The process in which a trachea is generated and organized. The trachea is the portion of the airway that attaches to the bronchi as it branches.
60440	trachea formation	P	The process pertaining to the initial formation of a trachea from unspecified parts. The process begins with the specific processes that contribute to the appearance of the discrete structure and ends when the trachea is recognizable. The trachea is the portion of the airway that attaches to the bronchi as it branches.
60441	epithelial tube branching involved in lung morphogenesis	P	The process in which a highly ordered sequence of patterning events generates the branched epithelial tubes of the lung, consisting of reiterated combinations of bud outgrowth, elongation, and dichotomous subdivision of terminal units.
60442	branching involved in prostate gland morphogenesis	P	The process in which the branching structure of the prostate gland is generated and organized. A branch is a division or offshoot from a main stem.
60443	mammary gland morphogenesis	P	The process in which anatomical structures of the mammary gland are generated and organized. Morphogenesis refers to the creation of shape. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk.
60444	branching involved in mammary gland duct morphogenesis	P	The process in which the branching structure of the mammary gland duct is generated and organized. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk.
60445	branching involved in salivary gland morphogenesis	P	The process in which the branching structure of the salivary gland is generated and organized.
60446	branching involved in open tracheal system development	P	The process in which the anatomical structures of branches in the open tracheal system are generated and organized.
60447	bud outgrowth involved in lung branching	P	The process in which a region of the lung epithelium initiates an outgrowth.
60448	dichotomous subdivision of terminal units involved in lung branching	P	The process in which a lung bud bifurcates.
60449	bud elongation involved in lung branching	P	The process in which a bud in the lung grows out from the point where it is formed.
60450	positive regulation of hindgut contraction	P	Any process that increases the frequency, rate or extent of muscle contraction of the hindgut, the posterior part of the alimentary canal, including the rectum, and the large intestine.
60451	negative regulation of hindgut contraction	P	Any process that decreases the frequency, rate or extent of muscle contraction of the hindgut, the posterior part of the alimentary canal, including the rectum, and the large intestine.
60452	positive regulation of cardiac muscle contraction	P	Any process that increases the frequency, rate or extent of cardiac muscle contraction.
60453	regulation of gastric acid secretion	P	Any process that modulates the rate frequency or extent of gastric secretion. Gastric secretion is the regulated release of gastric acid (hydrochloric acid) by parietal or oxyntic cells during digestion.
60454	positive regulation of gastric acid secretion	P	Any process that increases the rate frequency or extent of gastric secretion. Gastric secretion is the regulated release of gastric acid (hydrochloric acid) by parietal or oxyntic cells during digestion.
60455	negative regulation of gastric acid secretion	P	Any process that decreases the rate frequency or extent of gastric secretion. Gastric secretion is the regulated release of gastric acid (hydrochloric acid) by parietal or oxyntic cells during digestion.
60456	positive regulation of digestive system process	P	Any process that increases the frequency, rate or extent of a digestive system process, a physical, chemical, or biochemical process carried out by living organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism.
60457	negative regulation of digestive system process	P	Any process that decreases the frequency, rate or extent of a digestive system process, a physical, chemical, or biochemical process carried out by living organisms to break down ingested nutrients into components that may be easily absorbed and directed into metabolism.
60458	right lung development	P	The biological process whose specific outcome is the progression of a right lung from an initial condition to its mature state. This process begins with the formation of the right lung and ends with the mature structure. The right lung is the lung which is on the right side of the anterior posterior axis looking from a dorsal to ventral aspect.
60459	left lung development	P	The biological process whose specific outcome is the progression of a left lung from an initial condition to its mature state. This process begins with the formation of the left lung and ends with the mature structure. The left lung is the lung which is on the left side of the anterior posterior axis looking from a dorsal to ventral aspect.
60460	left lung morphogenesis	P	The process in which anatomical structures of the left lung are generated and organized.
60461	right lung morphogenesis	P	The process in which anatomical structures of the right lung are generated and organized.
60462	lung lobe development	P	The biological process whose specific outcome is the progression of a lung lobe from an initial condition to its mature state. This process begins with the formation of a lung lobe by branching morphogenesis and ends with the mature structure. A lung lobe is one of the rounded projections that compose the lung.
60463	lung lobe morphogenesis	P	The process in which the anatomical structures of a lung lobe are generated and organized. A lung lobe is a projection that extends from the lung.
60464	lung lobe formation	P	The developmental process pertaining to the initial formation of a lung lobe from unspecified parts. This process begins with the specific processes that contribute to the appearance of the lobe and ends when the structural rudiment is recognizable. A lung lobe is a projection that extends from the lung.
60465	pharynx development	P	The biological process whose specific outcome is the progression of a pharynx from an initial condition to its mature state. The pharynx is the part of the digestive system immediately posterior to the mouth.
60466	activation of meiosis involved in egg activation	P	Any process that starts the inactive process of meiosis in an egg after the egg has been fertilized or physiologically activated. Eggs generally arrest in meiosis and complete the process after activation.
60467	negative regulation of fertilization	P	Any process that decreases the rate, frequency or extent of fertilization. Fertilization is the union of gametes of opposite sexes during the process of sexual reproduction to form a zygote. It involves the fusion of the gametic nuclei (karyogamy) and cytoplasm (plasmogamy).
60468	prevention of polyspermy	P	The negative regulation of fertilization process that takes place as part of egg activation, ensuring that only a single sperm fertilizes the egg.
60469	positive regulation of transcription involved in egg activation	P	Any process that increases the rate, frequency or extent of transcription as a part of the process of egg activation.
60470	positive regulation of cytosolic calcium ion concentration involved in egg activation	P	The process that increases the concentration of calcium ions in the cytosol after fertilization or the physiological activation of an egg.
60471	cortical granule exocytosis	P	The process of secretion by a cell that results in the release of intracellular molecules contained within a cortical granule by fusion of the vesicle with the plasma membrane of a cell. A cortical granule is a specialized secretory vesicle that is released during egg activation that changes the surface of the egg to prevent polyspermy.
60472	positive regulation of cortical granule exocytosis by positive regulation of cytosolic calcium ion concentration	P	Any process that activates or increases the frequency, rate or extent of cortical granule exocytosis by directing movement of calcium ions (Ca2+) into the cytosol.
60473	cortical granule	C	A secretory vesicle that is stored under the cell membrane of an egg. These vesicles fuse with the egg plasma membrane as part of egg activation and are part of the block to polyspermy.
60474	positive regulation of flagellated sperm motility involved in capacitation	P	The process in which the controlled movement of a flagellated sperm cell is initiated as part of the process required for flagellated sperm to reach fertilization competence.
60475	positive regulation of actin filament polymerization involved in acrosome reaction	P	Any process that activates or increases the frequency, rate or extent of actin polymerization as part of the acrosome reaction.
60476	protein localization involved in acrosome reaction	P	The actin-based process in which a protein is transported to, or maintained in, a specific location in the sperm as part of the acrosome reaction.
60477	peptidyl-serine phosphorylation involved in acrosome reaction	P	The phosphorylation of peptidyl-serine to form peptidyl-O-phospho-L-serine that is part of the acrosome reaction.
60478	acrosomal vesicle exocytosis	P	The release of intracellular molecules contained within the acrosomal granule by fusion of the vesicle with the plasma membrane of the oocyte, requiring calcium ions.
60479	lung cell differentiation	P	The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features of a mature cell found in the lung. Differentiation includes the processes involved in commitment of a cell to a specific fate.
60480	lung goblet cell differentiation	P	The process in which a relatively unspecialized cell acquires specialized features of a lung goblet cell. A goblet cell is a cell of the epithelial lining that produces and secretes mucins.
60481	lobar bronchus epithelium development	P	The biological process whose specific outcome is the progression of a lobar bronchus epithelium from an initial condition to its mature state. This process begins with the formation of the lobar bronchus epithelium and ends with the mature structure. The lobar bronchus epithelium is the tissue made up of epithelial cells that lines the inside of the lobar bronchus.
60482	lobar bronchus development	P	The biological process whose specific outcome is the progression of a lobar bronchus from an initial condition to its mature state. This process begins with the formation of the lobar bronchus and ends with the mature structure. The lobar bronchus is the major airway within the respiratory tree that starts by division of the principal bronchi on both sides and ends at the point of its own subdivision into tertiary or segmental bronchi.
60483	lobar bronchus mesenchyme development	P	The biological process whose specific outcome is the progression of a lobar bronchus mesenchyme from an initial condition to its mature state. This process begins with the formation of the lobar bronchus mesenchyme and ends with the mature structure. The lobar bronchus mesenchyme is the mass of tissue composed of mesenchymal cells in the lobar bronchus.
60484	lung-associated mesenchyme development	P	The biological process whose specific outcome is the progression of a lung-associated mesenchyme from an initial condition to its mature state. This process begins with the formation of lung-associated mesenchyme and ends with the mature structure. Lung-associated mesenchyme is the tissue made up of loosely connected mesenchymal cells in the lung.
60485	mesenchyme development	P	The process whose specific outcome is the progression of a mesenchymal tissue over time, from its formation to the mature structure. A mesenchymal tissue is made up of loosely packed stellate cells.
60486	Clara cell differentiation	P	The process in which a relatively unspecialized cell acquires specialized features of a Clara cell. A Clara cell is an unciliated epithelial cell found in the respiratory and terminal bronchioles.
60487	lung epithelial cell differentiation	P	The process in which a relatively unspecialized cell acquires specialized features of an epithelial cell that contributes to the epithelium of the lung.
60488	orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis	P	The process in which a lung bud bifurcates perpendicular to the plane of the previous bud.
60489	planar dichotomous subdivision of terminal units involved in lung branching morphogenesis	P	The process in which a lung bud bifurcates parallel to the plane of the previous bud.
60490	lateral sprouting involved in lung morphogenesis	P	The process in which a branch forms along the side of the lung epithelial tube.
60491	regulation of cell projection assembly	P	Any process that modulates the rate, frequency, or extent of cell projection assembly.
60492	lung induction	P	The close range interaction of two or more cells or tissues that causes the cells of the foregut to change their fates and specify the development of the lung.
60493	mesenchymal-endodermal cell signaling involved in lung induction	P	Any process that mediates the transfer of information from a mesenchymal cell to an endodermal cell in the foregut and contributes to the formation of the lung bud.
60494	inductive mesenchymal-endodermal cell signaling	P	Any process that mediates the transfer of information from a mesenchymal cell to an endodermal cell changing the fate of the endodermal cell.
60495	cell-cell signaling involved in lung development	P	Any process that mediates the transfer of information from one cell to another and contributes to the progression of the lung, from its initial state to the mature structure.
60496	mesenchymal-epithelial cell signaling involved in lung development	P	Any process that mediates the transfer of information from a mesenchymal cell to an epithelial cell and contributes to the development of the lung.
60497	mesenchymal-endodermal cell signaling	P	Any process that mediates the transfer of information between a mesenchymal cell and an endodermal cell.
60498	retinoic acid receptor signaling pathway involved in lung bud formation	P	The series of molecular signals generated as a consequence of a retinoic acid receptor binding to one of its physiological ligands contributing to the formation of the primary lung bud.
60499	fibroblast growth factor receptor signaling pathway involved in lung induction	P	The series of molecular signals generated as a consequence of a fibroblast growth factor-type receptor binding to one of its physiological ligands resulting in the formation of the lung bud along the lateral-esophageal sulcus.
60500	regulation of transcription from RNA polymerase II promoter involved in lung bud formation	P	Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that contributes to the branching morphogenesis by which the initial primordium of the lung is formed.
60501	positive regulation of epithelial cell proliferation involved in lung morphogenesis	P	Any process that increases the rate or frequency of epithelial cell proliferation that results in the lung attaining its shape.
60502	epithelial cell proliferation involved in lung morphogenesis	P	The multiplication or reproduction of epithelial cells, resulting in the expansion of a cell population that contributes to the shaping of the lung.
60503	bud dilation involved in lung branching	P	The process in which a bud in the lung increases radially.
60504	positive regulation of epithelial cell proliferation involved in lung bud dilation	P	Any process that increases the rate or frequency of epithelial cell proliferation that results in the lung bud increasing in size radially.
60505	epithelial cell proliferation involved in lung bud dilation	P	The multiplication or reproduction of epithelial cells that contribute to the radial growth of a lung bud.
60506	smoothened signaling pathway involved in lung development	P	The series of molecular signals generated as a consequence of activation of the transmembrane Smoothened-type protein. This process contributes to lung development.
60507	epidermal growth factor receptor signaling pathway involved in lung development	P	The series of molecular signals generated as a consequence of an epidermal growth factor-type receptor binding to one of its physiological ligands. This process contributes to lung development.
60508	lung basal cell differentiation	P	The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features of a mature basal cell found in the lung. Differentiation includes the processes involved in commitment of a cell to a specific fate. A basal cell is an epithelial stem cell.
60509	Type I pneumocyte differentiation	P	The process in which a relatively unspecialized cell acquires specialized features of a Type I pneumocyte. A type I pneumocyte is a flattened cell with greatly attenuated cytoplasm and a paucity of organelles.
60510	Type II pneumocyte differentiation	P	The process in which a relatively unspecialized cell acquires specialized features of a Type II pneumocyte. A Type II pneumocyte is a surfactant secreting cell that contains abundant cytoplasm containing numerous lipid-rich multilamellar bodies.
60511	creation of an inductive signal by a mesenchymal cell involved in lung induction	P	The process in which splanchnic mesenchymal cells send a signal over a short range to endodermal cells inducing them to form the primary lung bud.
60512	prostate gland morphogenesis	P	The process in which the anatomical structures of a prostate gland are generated and organized.
60513	prostatic bud formation	P	The morphogenetic process in which a region of the fetal urogenital sinus epithelium is specified to become the prostate, resulting in prostate bud outgrowth.
60514	prostate induction	P	The close range interaction of the urogenital sinus mesenchyme and the urogenital sinus epithelium that causes the cells of the urogenital sinus epithelium to change their fates and specify the development of the prostate gland.
60515	prostate field specification	P	The process that results in the delineation of a specific region of the urogenital sinus epithelium into the area in which the prostate gland will develop.
60516	primary prostatic bud elongation	P	The increase in size of the prostatic bud as it forms.
60517	epithelial cell proliferation involved in prostatic bud elongation	P	The multiplication of epithelial cells, contributing to the expansion of the primary prostatic bud.
60518	cell migration involved in prostatic bud elongation	P	The orderly movement of epithelial cells from one site to another contributing to the elongation of the primary prostatic bud.
60519	cell adhesion involved in prostatic bud elongation	P	The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules that contributes to the elongation of the primary prostatic bud.
60520	activation of prostate induction by androgen receptor signaling pathway	P	Any series of molecular signals generated as a consequence of an androgen binding to its receptor in the urogenital sinus mesenchyme that initiates prostate induction. Prostate induction is the close range interaction of the urogenital sinus mesenchyme and the urogenital sinus epithelium that causes the cells of the urogenital sinus epithelium to change their fates and specify the development of the prostate gland.
60521	mesenchymal-epithelial cell signaling involved in prostate induction	P	Signaling at short range from urogenital sinus mesenchymal cells to cells of the urogenital epithelium resulting in the epithelial cells adopting a prostatic fate.
60522	inductive mesenchymal to epithelial cell signaling	P	Signaling at short range from mesenchymal cells to cells of an epithelium that results in a developmental change in the epithelial cells.
60523	prostate epithelial cord elongation	P	The developmental growth process in which solid chords of prostate epithelium increase in length.
60524	dichotomous subdivision of prostate epithelial cord terminal unit	P	The process in which a prostate epithelial cord bifurcates at its end.
60525	prostate glandular acinus development	P	The progression of a glandular acinus of the prostate gland over time, from its initial formation to the mature structure. The glandular acini are the saclike structures of the gland.
60526	prostate glandular acinus morphogenesis	P	The process in which the prostate glandular acini are generated and organized. The glandular acini are the saclike structures of the gland.
60527	prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis	P	The branching morphogenesis process in which the prostate epithelial cords branch freely to create the structure of the prostate acini.
60528	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development	P	The process in which a relatively unspecialized epithelial cell acquires specialized features of a secretory columnal luminar epithelial cell of the prostate.
60529	squamous basal epithelial stem cell differentiation involved in prostate gland acinus development	P	The process in which a relatively unspecialized epithelial cell acquires specialized features of a squamous basal epithelial stem cell of the prostate.
60530	smooth muscle cell differentiation involved in prostate glandular acinus development	P	The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell of the prostate glandular acinus.
60531	neuroendocrine cell differentiation involved in prostate gland acinus development	P	The process in which relatively unspecialized cells acquires specialized structural and functions of a neuroendocrine cell of the prostate gland acinus.
60532	bronchus cartilage development	P	The process whose specific outcome is the progression of lung cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate.
60533	bronchus cartilage morphogenesis	P	The process in which the bronchus cartilage is generated and organized. The bronchus cartilage is the connective tissue of the portion of the airway that connects to the lungs.
60534	trachea cartilage development	P	The process whose specific outcome is the progression of the tracheal cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate.
60535	trachea cartilage morphogenesis	P	The process in which the anatomical structures of cartilage in the trachea are generated and organized.
60536	cartilage morphogenesis	P	The process in which the anatomical structures of cartilage are generated and organized.
60537	muscle tissue development	P	The progression of muscle tissue over time, from its initial formation to its mature state. Muscle tissue is a contractile tissue made up of actin and myosin fibers.
60538	skeletal muscle organ development	P	The progression of a skeletal muscle organ over time from its initial formation to its mature state. A skeletal muscle organ includes the skeletal muscle tissue and its associated connective tissue.
60539	diaphragm development	P	The progression of the diaphragm over time from its initial formation to the mature structure. The diaphragm is a skeletal muscle that is responsible for contraction and expansion of the lungs.
60540	diaphragm morphogenesis	P	The process in which the anatomical structures of the diaphragm are generated and organized.
60541	respiratory system development	P	The progression of the respiratory system over time from its formation to its mature structure. The respiratory system carries out respiratory gaseous exchange.
60542	regulation of strand invasion	P	Any process that modulates the rate, frequency or extent of strand invasion. Strand invasion is the process in which the nucleoprotein complex (composed of the broken single-strand DNA and the recombinase) searches and identifies a region of homology in intact duplex DNA. The broken single-strand DNA displaces the like strand and forms Watson-Crick base pairs with its complement, forming a duplex in which each strand is from one of the two recombining DNA molecules.
60543	negative regulation of strand invasion	P	Any process that decreases the rate, frequency or extent of strand invasion. Strand invasion is the process in which the nucleoprotein complex (composed of the broken single-strand DNA and the recombinase) searches and identifies a region of homology in intact duplex DNA. The broken single-strand DNA displaces the like strand and forms Watson-Crick base pairs with its complement, forming a duplex in which each strand is from one of the two recombining DNA molecules.
60544	regulation of necroptotic process	P	Any process that modulates the rate, frequency or extent of a necroptotic process, a necrotic cell death process that results from the activation of endogenous cellular processes, such as signaling involving death domain receptors or Toll-like receptors.
60545	positive regulation of necroptotic process	P	Any process that increases the rate, frequency or extent of a necroptotic process, a necrotic cell death process that results from the activation of endogenous cellular processes, such as signaling involving death domain receptors or Toll-like receptors.
60546	negative regulation of necroptotic process	P	Any process that decreases the rate, frequency or extent of a necroptotic process, a necrotic cell death process that results from the activation of endogenous cellular processes, such as signaling involving death domain receptors or Toll-like receptors.
60547	negative regulation of necrotic cell death	P	Any process that decreases the rate, frequency or extent of necrotic cell death. Necrotic cell death is a cell death process that is morphologically characterized by a gain in cell volume (oncosis), swelling of organelles, plasma membrane rupture and subsequent loss of intracellular contents.
60548	negative regulation of cell death	P	Any process that decreases the rate or frequency of cell death. Cell death is the specific activation or halting of processes within a cell so that its vital functions markedly cease, rather than simply deteriorating gradually over time, which culminates in cell death.
60549	regulation of fructose 1,6-bisphosphate 1-phosphatase activity	P	Any process that modulates the rate, frequency or extent of fructose 1,6-bisphosphate 1-phosphatase activity. Fructose 1,6-bisphosphate 1-phosphatase activity is the catalysis of the reaction: D-fructose 1,6-bisphosphate + H2O = D-fructose 6-phosphate + phosphate.
60550	positive regulation of fructose 1,6-bisphosphate 1-phosphatase activity	P	Any process that increases the rate, frequency or extent of fructose 1,6-bisphosphate 1-phosphatase activity. Fructose 1,6-bisphosphate 1-phosphatase activity is the catalysis of the reaction: D-fructose 1,6-bisphosphate + H2O = D-fructose 6-phosphate + phosphate.
60551	regulation of fructose 1,6-bisphosphate metabolic process	P	Any process that modulates the rate, frequency or extent of fructose 1,6-bisphosphate metabolism. Fructose 1,6-bisphosphate metabolism is the chemical reactions and pathways involving fructose 1,6-bisphosphate, also known as FBP. The D enantiomer is a metabolic intermediate in glycolysis and gluconeogenesis.
60552	positive regulation of fructose 1,6-bisphosphate metabolic process	P	Any process that increases the rate, frequency or extent of fructose 1,6-bisphosphate metabolism. Fructose 1,6-bisphosphate metabolism is the chemical reactions and pathways involving fructose 1,6-bisphosphate, also known as FBP. The D enantiomer is a metabolic intermediate in glycolysis and gluconeogenesis.
60556	regulation of vitamin D biosynthetic process	P	Any process that modulates the rate frequency or extent of a vitamin D biosynthetic process. Vitamin D biosynthesis is the chemical reactions and pathways resulting in the formation of vitamin D, any of a group of related, fat-soluble compounds that are derived from delta-5,7 steroids and play a central role in calcium metabolism. Specific forms of vitamin D include calciferol (ergocalciferol; vitamin D2) and cholecalciferol (calciol; vitamin D3).
60557	positive regulation of vitamin D biosynthetic process	P	Any process that increases the rate, frequency or extent of a vitamin D biosynthetic process. Vitamin D biosynthesis is the chemical reactions and pathways resulting in the formation of vitamin D, any of a group of related, fat-soluble compounds that are derived from delta-5,7 steroids and play a central role in calcium metabolism. Specific forms of vitamin D include calciferol (ergocalciferol; vitamin D2) and cholecalciferol (calciol; vitamin D3).
60558	regulation of calcidiol 1-monooxygenase activity	P	Any process that modulates the rate, frequency or extent of calcidiol 1-monooxygenase activity. Calcidiol 1-monooxygenase activity is catalysis of the reaction: calcidiol + NADPH + H+ + O2 = calcitriol + NADP+ + H2O.
60559	positive regulation of calcidiol 1-monooxygenase activity	P	Any process that increases the rate, frequency or extent of calcidiol 1-monooxygenase activity. Calcidiol 1-monooxygenase activity is the catalysis of the reaction: calcidiol + NADPH + H+ + O2 = calcitriol + NADP+ + H2O.
60560	developmental growth involved in morphogenesis	P	The increase in size or mass of an anatomical structure that contributes to the structure attaining its shape.
60561	apoptotic process involved in morphogenesis	P	Any apoptotic process that contributes to the shaping of an anatomical structure.
60562	epithelial tube morphogenesis	P	The process in which the anatomical structures of a tube are generated and organized from an epithelium. Epithelial tubes transport gases, liquids and cells from one site to another and form the basic structure of many organs and tissues, with tube shape and organization varying from the single-celled excretory organ in Caenorhabditis elegans to the branching trees of the mammalian kidney and insect tracheal system.
60563	neuroepithelial cell differentiation	P	The process in which epiblast cells acquire specialized features of neuroepithelial cells.
60566	positive regulation of DNA-templated transcription, termination	P	Any process that increases the rate, frequency or extent of DNA-templated transcription termination, the process in which transcription is completed; the formation of phosphodiester bonds ceases, the RNA-DNA hybrid dissociates, and RNA polymerase releases the DNA.
60567	negative regulation of DNA-templated transcription, termination	P	Any process that decreases the rate, frequency or extent of DNA-dependent transcription termination, the process in which transcription is completed; the formation of phosphodiester bonds ceases, the RNA-DNA hybrid dissociates, and RNA polymerase releases the DNA.
60568	regulation of peptide hormone processing	P	Any process that modulates the rate, frequency or extent of peptide hormone processing. Peptide hormone processing is the generation of a mature peptide hormone by posttranslational processing of a prohormone.
60569	positive regulation of peptide hormone processing	P	Any process that increases the rate, frequency or extent of peptide hormone processing. Peptide hormone processing is the generation of a mature peptide hormone by posttranslational processing of a prohormone.
60570	negative regulation of peptide hormone processing	P	Any process that decreases the rate, frequency or extent of peptide hormone processing. Peptide hormone processing is the generation of a mature peptide hormone by posttranslational processing of a prohormone.
60571	morphogenesis of an epithelial fold	P	The morphogenetic process in which an epithelial sheet bends along a linear axis.
60572	morphogenesis of an epithelial bud	P	The morphogenetic process in which a bud forms from an epithelial sheet. A bud is a protrusion that forms form the sheet by localized folding.
60573	cell fate specification involved in pattern specification	P	The process involved in the specification of the identity of a cell in a field of cells that is being instructed as to how to differentiate. Once specification has taken place, that cell will be committed to differentiate down a specific pathway if left in its normal environment.
60574	intestinal epithelial cell maturation	P	The developmental process, independent of morphogenetic (shape) change, that is required for a columna/cuboidal epithelial cell of the intestine to attain its fully functional state. A columnar/cuboidal epithelial cell of the intestine mature as they migrate from the intestinal crypt to the villus.
60575	intestinal epithelial cell differentiation	P	The process in which a relatively unspecialized cell acquires specialized features of a columnar/cuboidal epithelial cell of the intestine.
60576	intestinal epithelial cell development	P	The process whose specific outcome is the progression of a columnar/cuboidal epithelial cell of the intestine over time, from its formation to the mature structure.
60577	pulmonary vein morphogenesis	P	The process in which the anatomical structure of the pulmonary venous blood vessels are generated and organized. Pulmonary veins are blood vessels that transport blood from the lungs to the heart.
60578	superior vena cava morphogenesis	P	The process in which the anatomical structure of superior vena cava generated and organized. The superior vena cava is a blood vessel that transports blood from the upper body to the heart.
60579	ventral spinal cord interneuron fate commitment	P	The process in which the developmental fate of a cell becomes restricted such that it will develop into a ventral spinal cord interneuron. Ventral spinal cord interneurons are cells located in the ventral portion of the spinal cord that transmit signals between sensory and motor neurons and are required for reflexive responses.
60580	ventral spinal cord interneuron fate determination	P	The process in which a cell becomes capable of differentiating autonomously into a ventral spinal cord interneuron regardless of its environment; upon determination, the cell fate cannot be reversed. Ventral spinal cord interneurons are cells located in the ventral portion of the spinal cord that transmit signals between sensory and motor neurons and are required for reflexive responses.
60581	cell fate commitment involved in pattern specification	P	The commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells within a field of cells that will exhibit a certain pattern of differentiation. Positional information is established through protein signals that emanate from a localized source within a developmental field resulting in specification of a cell type. Those signals are then interpreted in a cell-autonomous manner resulting in the determination of the cell type.
60582	cell fate determination involved in pattern specification	P	A process involved in commitment of a cell to a fate in a developmental field. Once determination has taken place, a cell becomes committed to differentiate down a particular pathway regardless of its environment.
60583	regulation of actin cortical patch localization	P	Any process that modulates the localization of an actin cortical patch. An actin cortical patch is a discrete actin-containing structure found just beneath the plasma membrane in fungal cells.
60584	regulation of prostaglandin-endoperoxide synthase activity	P	Any process that modulates the rate, frequency or prostaglandin-endoperoxide synthase activity. Prostaglandin-endoperoxide synthase activity is the catalysis of the reaction: arachidonate + donor-H2 + 2 O2 = prostaglandin H2 + acceptor + H2O.
60585	positive regulation of prostaglandin-endoperoxide synthase activity	P	Any process that increases the rate, frequency or extent of prostaglandin-endoperoxide synthase activity. Prostaglandin-endoperoxide synthase activity is the catalysis of the reaction: arachidonate + donor-H2 + 2 O2 = prostaglandin H2 + acceptor + H2O.
60586	multicellular organismal iron ion homeostasis	P	Any process involved in the maintenance of the distribution of iron stores within tissues and organs of a multicellular organism.
60587	regulation of lipoprotein lipid oxidation	P	Any process that modulates the rate, frequency or extent of lipoprotein lipid oxidation. Lipoprotein lipid oxidation is the modification of a lipoprotein by oxidation of the lipid group.
60588	negative regulation of lipoprotein lipid oxidation	P	Any process that decreases the rate, frequency or extent of lipoprotein lipid oxidation. Lipoprotein lipid oxidation is the modification of a lipoprotein by oxidation of the lipid group.
60589	nucleoside-triphosphatase regulator activity	F	Modulates the rate of NTP hydrolysis by a NTPase.
60590	ATPase regulator activity	F	Modulates the rate of ATP hydrolysis by an ATPase.
60591	chondroblast differentiation	P	The process in which a mesenchymal cell, acquires specialized structural and/or functional features of a chondroblast. Differentiation includes the processes involved in commitment of a cell to a chondroblast fate. A chondroblast is a precursor cell to chondrocytes.
60592	mammary gland formation	P	The process pertaining to the initial formation of the mammary gland from unspecified parts. The process begins with formation of the mammary line and ends when the solid mammary bud invades the primary mammary mesenchyme.
60593	Wnt signaling pathway involved in mammary gland specification	P	The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of a cell in the epidermis resulting in the formation of the mammary line. The mammary line is a ridge of epidermal cells that will form the mammary placodes.
60594	mammary gland specification	P	The regionalization process in which the mammary line is specified. The mammary line is a ridge of epidermal cells that will form the mammary placodes.
60595	fibroblast growth factor receptor signaling pathway involved in mammary gland specification	P	The series of molecular signals initiated by binding of a fibroblast growth factor to its receptor on the surface of al cell in the epidermis resulting in the formation of the mammary line. The mammary line is a ridge of epidermal cells that will form the mammary placodes.
60596	mammary placode formation	P	The developmental process in which the mammary placode forms. The mammary placode is a transient lens shaped structure that will give rise to the mammary bud proper.
60597	regulation of transcription from RNA polymerase II promoter involved in mammary gland formation	P	Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that contributes to the formation of the mammary line, placode or bud.
60598	dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis	P	The process in which the terminal end of a mammary duct bifurcates.
60599	lateral sprouting involved in mammary gland duct morphogenesis	P	The process in which a branch forms along the side of a mammary duct.
60600	dichotomous subdivision of an epithelial terminal unit	P	The process in which an epithelial cord, rod or tube bifurcates at its end.
60601	lateral sprouting from an epithelium	P	The process in which a branch forms along the side of an epithelium.
60602	branch elongation of an epithelium	P	The growth process in which a branch increases in length from its base to its tip.
60603	mammary gland duct morphogenesis	P	The process in which anatomical structures of the mammary ducts are generated and organized. Mammary ducts are epithelial tubes that transport milk.
60604	mammary gland duct cavitation	P	Creation of the central hole of the mammary gland duct by the hollowing out of a solid rod.
60605	tube lumen cavitation	P	The formation of a lumen by hollowing out a solid rod or cord.
60606	tube closure	P	Creation of the central hole of a tube in an anatomical structure by sealing the edges of an epithelial fold.
60607	cell-cell adhesion involved in sealing an epithelial fold	P	The attachment of one cell to another cell along the edges of two epithelial folds, giving rise to the lumen of an epithelial tube.
60608	cell-cell adhesion involved in neural tube closure	P	The attachment of one cell to another cell along the edges of two epithelial folds, giving rise to the lumen of the neural tube.
60609	apoptotic process involved in tube lumen cavitation	P	Any apoptotic process that contributes to the hollowing out of an epithelial rod or cord to form the central hole in a tube.
60610	mesenchymal cell differentiation involved in mammary gland development	P	The process in which a relatively unspecialized cell acquires specialized features of a mammary gland mesenchymal cell. Mammary gland mesenchymal cells form a loosely connected network of cells that surround the mammary ducts.
60611	mammary gland fat development	P	The progression of the mammary gland fat over time, from its formation to the mature structure. The mammary fat is an adipose structure in the gland that is invaded by the mammary ducts.
60612	adipose tissue development	P	The process whose specific outcome is the progression of adipose tissue over time, from its formation to the mature structure. Adipose tissue is specialized tissue that is used to store fat.
60613	fat pad development	P	The progression of a fat pad from its initial formation to its mature structure. A fat pad is an accumulation of adipose tissue.
60614	negative regulation of mammary gland development in males by androgen receptor signaling pathway	P	Any process that decreases the rate or extent of mammary gland development in the male by an androgen binding to its receptor, causing a change in state or activity of a cell.
60615	mammary gland bud formation	P	The morphogenetic process in which a bud forms from the mammary placode. A mammary bud is bulb of epithelial cells that is distinct from the surrounding epidermis.
60616	mammary gland cord formation	P	The process in which the mammary gland cord forms by elongation of the mammary bud. The cord is formed once the elongating bud breaks through the mesenchyme and reaches the fat pad.
60617	positive regulation of mammary placode formation by mesenchymal-epithelial signaling	P	Any process that initiates the formation of a mammary placode through a mechanism that mediates the transfer of information from a mesenchymal cell to an epithelial cell resulting in the epithelial cell adopting the identity of a cell of the mammary placode.
60618	nipple development	P	The progression of the nipple over time, from its formation to the mature structure. The nipple is a part of the mammary gland that protrudes from the surface ectoderm.
60619	cell migration involved in mammary placode formation	P	The orderly movement of epithelial cells within the mammary line that contributes to the formation of the mammary placode.
60620	regulation of cholesterol import	P	Any process that modulates the rate, frequency or extent of cholesterol import. Cholesterol import is the directed movement of cholesterol into a cell or organelle.
60621	negative regulation of cholesterol import	P	Any process that decreases the rate, frequency or extent of cholesterol import. Cholesterol import is the directed movement of cholesterol into a cell or organelle.
60622	regulation of ascospore wall beta-glucan biosynthetic process	P	Any process that modulates the rate, frequency or extent of ascospore wall beta-glucan biosynthetic process, the chemical reactions and pathways resulting in the formation of beta-glucans, compounds composed of glucose residues linked by beta-D-glucosidic bonds, found in the walls of ascospores.
60623	regulation of chromosome condensation	P	Any process that modulates the rate, frequency, or extent of chromosome condensation, the progressive compaction of dispersed interphase chromatin into threadlike chromosomes prior to mitotic or meiotic nuclear division, or during apoptosis, in eukaryotic cells.
60624	regulation of ascospore wall (1->3)-beta-D-glucan biosynthetic process	P	Any process that modulates the rate, frequency, or extent of ascospore wall (1->3)-beta-D-glucan biosynthetic process, the chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D--glucosidic bonds, found in the walls of ascospores.
60625	regulation of protein deneddylation	P	Any process that modulates the rate, frequency, or extent of protein deneddylation, the removal of a ubiquitin-like protein of the NEDD8 type from a protein.
60626	regulation of cullin deneddylation	P	Any process that modulates the rate, frequency or extent of cullin deneddylation, the modification of cullins by removal of ubiquitin-like protein NEDD8 (RUB1).
60627	regulation of vesicle-mediated transport	P	Any process that modulates the rate, frequency, or extent of vesicle-mediated transport, the directed movement of substances, either within a vesicle or in the vesicle membrane, into, out of or within a cell.
60628	regulation of ER to Golgi vesicle-mediated transport	P	Any process that modulates the rate, frequency, or extent of ER to Golgi vesicle-mediated transport, the directed movement of substances from the endoplasmic reticulum (ER) to the Golgi, mediated by COP II vesicles. Small COP II coated vesicles form from the ER and then fuse directly with the cis-Golgi. Larger structures are transported along microtubules to the cis-Golgi.
60629	regulation of homologous chromosome segregation	P	Any process that modulates the rate, frequency, or extent of homologous chromosome segregation, the cell cycle process in which replicated homologous chromosomes are organized and then physically separated and apportioned to two sets during the first division of the meiotic cell cycle. Each replicated chromosome, composed of two sister chromatids, aligns at the cell equator, paired with its homologous partner; this pairing off, referred to as synapsis, permits genetic recombination. One homolog (both sister chromatids) of each morphologic type goes into each of the resulting chromosome sets.
60631	regulation of meiosis I	P	Any process that modulates the rate, frequency, or extent of meiosis I, a cell cycle process comprising the steps by which a cell progresses through the first phase of meiosis, in which cells divide and homologous chromosomes are paired and segregated from each other, producing two daughter cells.
60632	regulation of microtubule-based movement	P	Any process that modulates the rate, frequency, or extent of microtubule-based movement, the movement of organelles, other microtubules and other particles along microtubules, mediated by motor proteins.
60633	negative regulation of transcription initiation from RNA polymerase II promoter	P	Any process that decreases the rate, frequency or extent of a process involved in starting transcription from an RNA polymerase II promoter.
60634	regulation of 4,6-pyruvylated galactose residue biosynthetic process	P	Any process that modulates the rate, frequency, or extent of 4,6-pyruvylated galactose residue biosynthetic process, the chemical reactions and pathways resulting in the formation of the pyruvylated galactose residue 4-6-O-[(R)(1-carboxyethylidine)]-Gal-beta-(1->3)-. The galactose residue is part of a larger polysaccharide chain.
60635	positive regulation of (1->3)-beta-D-glucan biosynthetic process	P	Any process that increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans.
60636	negative regulation of (1->3)-beta-D-glucan biosynthetic process	P	Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans.
60637	positive regulation of lactation by mesenchymal-epithelial cell signaling	P	The process that increases the rate, frequency, or extent of lactation as a result of the secretion of a signal from the mammary fat and its reception by a mammary epithelial cell.
60638	mesenchymal-epithelial cell signaling	P	Any process that mediates the transfer of information from a mesenchymal cell to an epithelial cell where it is received and interpreted.
60639	positive regulation of salivary gland formation by mesenchymal-epithelial signaling	P	Any process that induces the formation of the salivary gland field by means of the secretion of a signal by a mesenchymal cell and its reception and interpretation by an epithelial cell resulting in it adopting the identity of a salivary gland bud cell.
60640	positive regulation of dentin-containing tooth bud formation by mesenchymal-epithelial signaling	P	Any process that initiates the formation of a tooth bud by the secretion of a signal from a mesenchymal cell and its reception and subsequent change in the identity of an epithelial cell of the tooth bud.
60641	mammary gland duct regression in males	P	The process in which the epithelium of the mammary duct is destroyed in males.
60642	white fat cell differentiation involved in mammary gland fat development	P	The process in which a preadipocyte acquires specialized features of a white adipocyte of the mammary gland. White adipocytes have cytoplasmic lipids arranged in a unique vacuole.
60643	epithelial cell differentiation involved in mammary gland bud morphogenesis	P	The process in which a cell of the mammary placode becomes a cell of the mammary gland bud.
60644	mammary gland epithelial cell differentiation	P	The process in which a relatively unspecialized epithelial cell becomes a more specialized epithelial cell of the mammary gland.
60645	peripheral mammary gland bud epithelial cell differentiation	P	The process in which a relatively unspecialized epithelial cell of the mammary placode becomes an epithelial cell at the periphery of the mammary gland bud. Cells at the periphery of the bud are larger that those of the surrounding epithelium and are arranged concentrically.
60646	internal mammary gland bud epithelial cell differentiation	P	The process in which a relatively unspecialized epithelial cell of the mammary placode becomes an internal epithelial cell of the mammary gland bud. Internal cells are small and of irregular shape.
60647	mesenchymal cell condensation involved in mammary fat development	P	The cell adhesion process in which mammary mesenchyme cells adhere to one another in the initial stages of the formation of mammary fat development.
60648	mammary gland bud morphogenesis	P	The process in which anatomical structures of the mammary gland buds are generated and organized. Mammary gland buds form by an outpocketing of the mammary placodes and grow to invade the mammary fat, when they form the mammary cord.
60649	mammary gland bud elongation	P	The process in which the mammary gland bud grows along its axis.
60650	epithelial cell proliferation involved in mammary gland bud elongation	P	The multiplication or reproduction of mammary gland bud epithelial cells, resulting in the elongation of the bud.
60651	regulation of epithelial cell proliferation involved in mammary gland bud elongation	P	Any process that modulates the frequency, rate or extent of mammary gland bud epithelial cell proliferation that results in the elongation of the bud.
60652	mammary gland cord morphogenesis	P	The process in which anatomical structures of the mammary gland cord are generated and organized. Mammary gland cords form when the mammary gland bud invades the mammary fat.
60653	epithelial cell differentiation involved in mammary gland cord morphogenesis	P	The process in which a relatively unspecialized epithelial cell becomes a more specialized epithelial cell of the mammary gland cord. Epithelial cells of the mammary cord give it its funnel-like shape and some are cornified.
60654	mammary gland cord elongation	P	The process in which the mammary gland sprout grows along its axis.
60655	branching involved in mammary gland cord morphogenesis	P	The process in which the branching structure of the mammary gland cord is generated and organized. The mammary gland cord is a solid epithelial structure that will hollow out, forming the mammary duct.
60656	regulation of branching involved in mammary cord morphogenesis by fat precursor cell-epithelial cell signaling	P	Any process that modulates the rate, frequency, or extent of branching of the mammary gland cord as a result of a signal being created by a mammary fat precursor cell and its subsequent reception and interpretation by a mammary cord epithelial cell.
60657	regulation of mammary gland cord elongation by mammary fat precursor cell-epithelial cell signaling	P	Any process that modulates the rate, frequency, or extent of mammary gland cord elongation as a result of a signal being created by a mesenchymal cell that is a precursor to the mammary fat and its subsequent reception and interpretation by an mammary cord epithelial cell.
60658	nipple morphogenesis	P	The process in which the nipple is generated and organized.
60659	nipple sheath formation	P	The developmental process pertaining to the initial formation of the nipple sheath from the unspecified epidermis. This process begins with a circular ingrowth of the epidermis around the region of the mammary sprout. It ends before the region begins to elevate.
60660	epidermis morphogenesis involved in nipple formation	P	The process in which the epidermis of the nipple sheath is uplifted to form an umbrella-like projection.
60661	submandibular salivary gland formation	P	The developmental process pertaining to the initial formation of a submandibular salivary gland. This process begins with a thickening of the epithelium next to the tongue and ends when a bud linked to the oral surface is formed.
60662	salivary gland cavitation	P	The process in which the solid core of salivary epithelium gives rise to the hollow tube of the gland.
60663	apoptotic process involved in salivary gland cavitation	P	Any apoptotic process in which the solid core of the gland is hollowed out to form the duct.
60664	epithelial cell proliferation involved in salivary gland morphogenesis	P	The multiplication or reproduction of epithelial cells of the submandibular salivary gland, resulting in the expansion of a cell population and the shaping of the gland.
60665	regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling	P	Any process that modulates the rate, frequency, or extent of branching involved in salivary gland morphogenesis as a result of signals being generated by the mesenchyme and received and interpreted by the salivary gland epithelium.
60666	dichotomous subdivision of terminal units involved in salivary gland branching	P	The process in which a salivary epithelial cord bifurcates at its end.
60667	branch elongation involved in salivary gland morphogenesis	P	The differential growth of the salivary branches along their axis, resulting in the growth of a branch.
60668	regulation of branching involved in salivary gland morphogenesis by extracellular matrix-epithelial cell signaling	P	Any process that modulates the rate, frequency, or extent of salivary gland branching as a result of the transfer of information from the extracellular matrix to the epithelium of the salivary gland.
60669	embryonic placenta morphogenesis	P	The process in which the embryonic placenta is generated and organized.
60670	branching involved in labyrinthine layer morphogenesis	P	The process in which the branches of the fetal placental villi are generated and organized. The villous part of the placenta is called the labyrinth layer.
60671	epithelial cell differentiation involved in embryonic placenta development	P	The process in which a trophoblast cell acquires specialized features of an epithelial cell of the placental labyrinthine layer.
60672	epithelial cell morphogenesis involved in placental branching	P	The change in form (cell shape and size) that occurs when a trophoblast cell elongates to contribute to the branching of the placenta.
60673	cell-cell signaling involved in placenta development	P	Any process that mediates the transfer of information from one cell to another.
60674	placenta blood vessel development	P	The process whose specific outcome is the progression of a blood vessel of the placenta over time, from its formation to the mature structure.
60675	ureteric bud morphogenesis	P	The process in which the ureteric bud is generated and organized.
60676	ureteric bud formation	P	The developmental process pertaining to the initial formation of the ureteric bud from the Wolffian duct. This process begins when the bud protrudes from the duct and ends when it is a recognizable bud.
60677	ureteric bud elongation	P	The developmental growth in which the ureteric bud grows along its axis beginning with the growth of the primary ureteric bud and ending when the branches of the bud have elongated.
60678	dichotomous subdivision of terminal units involved in ureteric bud branching	P	The process in which a ureteric bud bifurcates at its end.
60679	trifid subdivision of terminal units involved in ureteric bud branching	P	The process in which a ureteric bud splits into three units at its end.
60680	lateral sprouting involved in ureteric bud morphogenesis	P	The process in which a branch forms along the side of a ureteric bud.
60681	branch elongation involved in ureteric bud branching	P	The growth of a branch of the ureteric bud along its axis.
60682	primary ureteric bud growth	P	The process in which the primary ureteric bud grows along its axis dorsally toward the metanephric blastema.
60683	regulation of branching involved in salivary gland morphogenesis by epithelial-mesenchymal signaling	P	Any process that modulates the rate, frequency, or extent of salivary gland branching as a result of the transfer of information from the epithelial cells to the mesenchymal cells of the salivary gland.
60684	epithelial-mesenchymal cell signaling	P	Any process that results in the transfer of information from an epithelial cell to a mesenchymal cell where it is interpreted.
60685	regulation of prostatic bud formation	P	Any process that modulates the rate, frequency, or extent of prostatic bud formation, the morphogenetic process in which a region of the fetal urogenital sinus epithelium is specified to become the prostate, resulting in prostate bud outgrowth.
60686	negative regulation of prostatic bud formation	P	Any process that decreases the rate, frequency, or extent of prostatic bud formation, the morphogenetic process in which a region of the fetal urogenital sinus epithelium is specified to become the prostate, resulting in prostate bud outgrowth.
60687	regulation of branching involved in prostate gland morphogenesis	P	Any process that modulates the rate, frequency, or extent of prostate gland branching, the process in which the branching structure of the prostate gland is generated and organized. A branch is a division or offshoot from a main stem.
60688	regulation of morphogenesis of a branching structure	P	Any process that modulates the rate, frequency, or extent of branching morphogenesis, the process in which the anatomical structures of branches are generated and organized.
60689	cell differentiation involved in salivary gland development	P	The process in which a relatively unspecialized cell acquires specialized structural and/or functional features that characterize the cells of the salivary gland.
60690	epithelial cell differentiation involved in salivary gland development	P	The process in which a relatively unspecialized cell acquire specialized structural and/or functional features of an epithelial cell of the salivary gland.
60691	epithelial cell maturation involved in salivary gland development	P	The developmental process, independent of morphogenetic (shape) change, that is required for an epithelial cell of the salivary gland to attain its fully functional state.
60692	mesenchymal cell differentiation involved in salivary gland development	P	The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal cell of the salivary gland. A mesenchymal cell is a loosely associated cell that is part of the connective tissue in an organism. Mesenchymal cells give rise to more mature connective tissue cell types.
60693	regulation of branching involved in salivary gland morphogenesis	P	Any process that modulates the rate, frequency, or extent of branching morphogenesis in the salivary gland epithelium.
60694	regulation of cholesterol transporter activity	P	Any process that modulates the rate, frequency, or extent of cholesterol transporter activity.
60695	negative regulation of cholesterol transporter activity	P	Any process that decreases the rate, frequency, or extent of cholesterol transporter activity.
60696	regulation of phospholipid catabolic process	P	Any process that modulates the rate, frequency, or extent of phospholipid catabolism, the chemical reactions and pathways resulting in the breakdown of phospholipids, any lipid containing phosphoric acid as a mono- or diester.
60697	positive regulation of phospholipid catabolic process	P	Any process that increases the rate, frequency, or extent of phospholipid catabolism, the chemical reactions and pathways resulting in the breakdown of phospholipids, any lipid containing phosphoric acid as a mono- or diester.
60698	endoribonuclease inhibitor activity	F	Stops, prevents or reduces the activity of an endoribonuclease, any enzyme that catalyzes the hydrolysis of ester linkages within ribonucleic acid by creating internal breaks.
60699	regulation of endoribonuclease activity	P	Any process that modulates the rate, frequency or extent of the catalysis of the hydrolysis of ester linkages within ribonucleic acid by creating internal breaks.
60700	regulation of ribonuclease activity	P	Any process that modulates the rate, frequency, or extent of ribonuclease activity, catalysis of the hydrolysis of phosphodiester bonds in chains of RNA.
60701	negative regulation of ribonuclease activity	P	Any process that decreases the rate, frequency, or extent of ribonuclease activity, catalysis of the hydrolysis of phosphodiester bonds in chains of RNA.
60702	negative regulation of endoribonuclease activity	P	Any process that decreases the rate, frequency or extent of the catalysis of the hydrolysis of ester linkages within ribonucleic acid by creating internal breaks.
60703	deoxyribonuclease inhibitor activity	F	Stops, prevents or reduces the activity of deoxyribonuclease.
60704	acinar cell differentiation involved in salivary gland development	P	The process in which a relatively unspecialized cell acquires specialized structural and/or functional features that characterize an acinar cell of the salivary gland. Acinar cells are protein-secreting cells in the gland.
60705	neuron differentiation involved in salivary gland development	P	The process in which a relatively unspecialized cell acquires specialized structural and/or functional features that characterize the neurons of the salivary gland.
60706	cell differentiation involved in embryonic placenta development	P	The process in which a relatively unspecialized cell acquires specialized features of the embryonic placenta.
60707	trophoblast giant cell differentiation	P	The process in which a relatively unspecialized cell acquires specialized features of a trophoblast giant cell of the placenta. Trophoblast giant cells are the cell of the placenta that line the maternal decidua.
60708	spongiotrophoblast differentiation	P	The process in which a relatively unspecialized cell of the ectoplacental cone acquires specialized features of a spongiotrophoblast of the placenta. A spongiotrophoblast cell is a basophilic cell.
60709	glycogen cell differentiation involved in embryonic placenta development	P	The process in which a relatively unspecialized cell acquires specialized features of a glycogen cell of the placenta. A glycogen cell is a vacuolated glycogen-rich cell that appears in compact cell islets of the spongiotrophoblast layer.
60710	chorio-allantoic fusion	P	The cell-cell adhesion process in which the cells of the chorion fuse to the cells of the allantois.
60711	labyrinthine layer development	P	The process in which the labyrinthine layer of the placenta progresses, from its formation to its mature state.
60712	spongiotrophoblast layer development	P	The process in which the spongiotrophoblast layer of the placenta progresses from its formation to its mature state.
60713	labyrinthine layer morphogenesis	P	The process in which the labyrinthine layer of the placenta is generated and organized.
60714	labyrinthine layer formation	P	The developmental process pertaining to the initial formation of the labyrinthine layer of the placenta.
60715	syncytiotrophoblast cell differentiation involved in labyrinthine layer development	P	The process in which a chorionic trophoblast cell acquires specialized features of a syncytiotrophoblast of the labyrinthine layer of the placenta.
60716	labyrinthine layer blood vessel development	P	The process whose specific outcome is the progression of a blood vessel of the labyrinthine layer of the placenta over time, from its formation to the mature structure. The embryonic vessels grow through the layer to come in close contact with the maternal blood supply.
60717	chorion development	P	The biological process whose specific outcome is the progression of a chorion from an initial condition to its mature state. This process begins with the formation of the structure and ends with the mature structure. The chorion is an extraembryonic membrane.
60718	chorionic trophoblast cell differentiation	P	The process in which relatively unspecialized cells of the ectoplacental cone acquire specialized structural and/or functional features that characterize chorionic trophoblasts. These cells will migrate towards the spongiotrophoblast layer and give rise to syncytiotrophoblasts of the labyrinthine layer.
60719	chorionic trophoblast cell development	P	The process whose specific outcome is the progression of the chorionic trophoblast over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate.
60720	spongiotrophoblast cell proliferation	P	The multiplication or reproduction of spongiotrophoblast cells, resulting in the expansion of the population in the spongiotrophoblast layer.
60721	regulation of spongiotrophoblast cell proliferation	P	Any process that modulates the rate, frequency or extent of spongiotrophoblast cell proliferation.
60722	cell proliferation involved in embryonic placenta development	P	The multiplication or reproduction of cells, resulting in the expansion of the population in the embryonic placenta.
60723	regulation of cell proliferation involved in embryonic placenta development	P	Any process that modulates the rate, frequency, or extent of cell proliferation involved in embryonic placenta development.
60724	coreceptor activity involved in epidermal growth factor receptor signaling pathway	F	Combining with an extracellular messenger, and in cooperation with a primary EGF receptor, initiating a change in cell activity through the EGF receptor signaling pathway.
60725	regulation of coreceptor activity	P	Any process that modulates the rate or frequency of coreceptor activity, combining with an extracellular or intracellular messenger, and in cooperation with a nearby primary receptor, initiating a change in cell activity.
60726	regulation of coreceptor activity involved in epidermal growth factor receptor signaling pathway	P	Any process that modulates the rate or frequency of coreceptor activity involved in epidermal growth factor receptor signaling pathway.
60727	positive regulation of coreceptor activity involved in epidermal growth factor receptor signaling pathway	P	Any process that increases the rate or frequency of coreceptor activity involved in epidermal growth factor receptor signaling pathway.
60728	negative regulation of coreceptor activity involved in epidermal growth factor receptor signaling pathway	P	Any process that decreases the rate or frequency of coreceptor activity involved in epidermal growth factor receptor signaling pathway.
60729	intestinal epithelial structure maintenance	P	A tissue homeostatic process required for the maintenance of the structure of the intestinal epithelium.
60730	regulation of intestinal epithelial structure maintenance	P	Any process that modulates the rate, frequency, or extent of intestinal epithelial structure maintenance, a tissue homeostatic process required for the maintenance of the structure of the intestinal epithelium.
60731	positive regulation of intestinal epithelial structure maintenance	P	Any process the increases the rate, frequency or extent of intestinal epithelial structure maintenance, a tissue homeostatic process required for the maintenance of the structure of the intestinal epithelium.
60732	positive regulation of inositol phosphate biosynthetic process	P	Any process that increases the rate, frequency or extent of inositol phosphate biosynthesis. Inositol phosphate biosynthetic processes are the chemical reactions and pathways resulting in the formation of an inositol phosphate, 1,2,3,4,5,6-cyclohexanehexol, with one or more phosphate groups attached.
60733	regulation of eIF2 alpha phosphorylation by amino acid starvation	P	Any process that modulates the rate, frequency, or extent of eIF2 alpha phosphorylation as a cellular response to amino acid starvation.
60734	regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation	P	Any process that modulates the rate, frequency, or extent of eIF2 alpha phosphorylation as a cellular response to endoplasmic reticulum stress.
60735	regulation of eIF2 alpha phosphorylation by dsRNA	P	Any process that modulates the rate, frequency, or extent of eIF2 alpha phosphorylation as a cellular response to double-stranded RNA.
60736	prostate gland growth	P	The increase in size or mass of the prostate gland where the increase in size or mass has the specific outcome of the progression of the gland, from its formation to its mature state.
60737	prostate gland morphogenetic growth	P	The differential increase in size or mass of the prostate gland that contributes to the gland attaining its form.
60738	epithelial-mesenchymal signaling involved in prostate gland development	P	Any process that results in the transfer of information from an epithelial cell to a mesenchymal cell where it is interpreted and contributes to the progression of the prostate gland over time.
60739	mesenchymal-epithelial cell signaling involved in prostate gland development	P	Any process that mediates the transfer of information from a mesenchymal cell to an epithelial cell where it is received and interpreted contributing to the progression of the prostate gland over time.
60740	prostate gland epithelium morphogenesis	P	The process in which the anatomical structures of epithelia of the prostate gland are generated and organized. An epithelium consists of closely packed cells arranged in one or more layers, that covers the outer surfaces of the body or lines any internal cavity or tube.
60741	prostate gland stromal morphogenesis	P	The process in which the prostate gland stroma is generated and organized. The prostate gland stroma is made up of the mesenchymal or fibroblast cells of the prostate gland.
60742	epithelial cell differentiation involved in prostate gland development	P	The process in which a relatively unspecialized cell acquires specialized features of an epithelial cell of the prostate gland.
60743	epithelial cell maturation involved in prostate gland development	P	The developmental process, independent of morphogenetic (shape) change, that is required for an epithelial cell of the prostate gland to attain its fully functional state. An epithelial cell is a cell usually found in a two-dimensional sheet with a free surface.
60744	mammary gland branching involved in thelarche	P	The process in which the branching structure of the mammary gland duct is generated and organized during the period of sexual maturity in mammals. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk.
60745	mammary gland branching involved in pregnancy	P	The process in which the branching structure of the mammary gland duct is generated and organized as a part of pregnancy.
60746	parental behavior	P	A reproductive behavior in which a parent cares for and rears offspring.
60747	oral incubation	P	A parental behavior in which fertilized eggs are taken into the mouth and held until hatching.
60748	tertiary branching involved in mammary gland duct morphogenesis	P	The branching process in which the mammary gland ducts form tertiary branches off of the secondary branches as part of diestrus and pregnancy.
60749	mammary gland alveolus development	P	The progression of the mammary gland alveolus over time, from its formation to its mature state. The mammary gland alveolus is a sac-like structure that is found in the mature gland.
60750	epithelial cell proliferation involved in mammary gland duct elongation	P	The multiplication or reproduction of mammary gland branch epithelial cells, resulting in the elongation of the branch. The mammary gland branch differs from the bud in that it is not the initial curved portion of the outgrowth.
60751	branch elongation involved in mammary gland duct branching	P	The developmental growth process in which a branch of a mammary gland duct elongates.
60752	intestinal phytosterol absorption	P	Any process in which phytosterols are taken up from the contents of the intestine.
60753	regulation of mast cell chemotaxis	P	Any process that modulates the rate, frequency or extent of mast cell chemotaxis. Mast cell chemotaxis is the movement of a mast cell in response to an external stimulus.
60754	positive regulation of mast cell chemotaxis	P	Any process that increases the rate, frequency or extent of mast cell chemotaxis. Mast cell chemotaxis is the movement of a mast cell in response to an external stimulus.
60755	negative regulation of mast cell chemotaxis	P	Any process that decreases the rate, frequency or extent of mast cell chemotaxis. Mast cell chemotaxis is the movement of a mast cell in response to an external stimulus.
60756	foraging behavior	P	Behavior by which an organism locates food.
60757	adult foraging behavior	P	Behavior by which an adult locates food.
60758	foraging behavior by probing substrate	P	Foraging behavior in which an anatomical part of the organism is inserted into the substrate to locate food.
60759	regulation of response to cytokine stimulus	P	Any process that modulates the rate, frequency, or extent of a response to cytokine stimulus.
60760	positive regulation of response to cytokine stimulus	P	Any process that increases the rate, frequency, or extent of a response to cytokine stimulus.
60761	negative regulation of response to cytokine stimulus	P	Any process that decreases the rate, frequency, or extent of a response to cytokine stimulus.
60762	regulation of branching involved in mammary gland duct morphogenesis	P	Any process that modulates the rate, frequency, or extent of branching involved in mammary gland duct morphogenesis.
60763	mammary duct terminal end bud growth	P	The morphogenetic growth of the large, club-shaped terminal end of a mammary gland duct during prepubertal growth and during puberty.
60764	cell-cell signaling involved in mammary gland development	P	Any process that mediates the transfer of information from one cell to another and contributes to the progression of the mammary gland, from its initial state to the mature structure.
60765	regulation of androgen receptor signaling pathway	P	Any process that modulates the rate, frequency, or extent of the androgen receptor signaling pathway.
60766	negative regulation of androgen receptor signaling pathway	P	Any process that decreases the rate, frequency, or extent of the androgen receptor signaling pathway.
60767	epithelial cell proliferation involved in prostate gland development	P	The multiplication or reproduction of epithelial cells, resulting in the expansion of a cell population that contributes to the progression of the prostate gland over time.
60768	regulation of epithelial cell proliferation involved in prostate gland development	P	Any process that modulates the rate, frequency or extent of epithelial cell proliferation that contributes to the progression of the prostate gland over time.
60769	positive regulation of epithelial cell proliferation involved in prostate gland development	P	Any process that increases the rate, frequency or extent of epithelial cell proliferation that contributes to the progression of the prostate gland over time.
60770	negative regulation of epithelial cell proliferation involved in prostate gland development	P	Any process that decreases the rate, frequency or extent of epithelial cell proliferation that contributes to the progression of the prostate gland over time.
60771	phyllotactic patterning	P	The radial pattern formation process that results in the formation of plant organs (leaves or leaf-like structures) or flower primordia around a central axis.
60772	leaf phyllotactic patterning	P	The radial pattern formation process that results in the formation of leaf primordia around the center of a shoot apical meristem.
60773	flower phyllotactic patterning	P	The radial pattern formation process that results in the formation of floral organ primordia around a central axis in a flower primordium.
60774	auxin mediated signaling pathway involved in phyllotactic patterning	P	The series of molecular signals generated in response to detection of auxin that contributes to the radial pattern formation process resulting in the formation of leaf or flower primordia around the center of a shoot apical meristem.
60775	planar cell polarity pathway involved in gastrula mediolateral intercalation	P	The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors including C-Jun N-terminal kinase (JNK) contributing to the interdigitation of cells along the mediolateral axis during gastrulation.
60776	simple leaf morphogenesis	P	The leaf morphogenesis process which results in the shaping of a simple leaf. A simple leaf is a leaf in which the lamina is undivided.
60777	compound leaf morphogenesis	P	The leaf morphogenesis process that results in the shaping of a compound leaf. A compound leaf is a leaf having two or more distinct leaflets that are evident as such from early in development.
60778	primary leaflet morphogenesis	P	The process in which the primary leaflet attains its shape. A primary leaflet is a leaflet that develops directly from the rachis.
60779	secondary leaflet morphogenesis	P	The process in which the secondary leaflet attains its shape. A secondary leaflet develops by branching or division of a primary leaflet.
60780	intercalary leaflet morphogenesis	P	The process in which the intercalary leaflet attains its shape. An intercalary leaflet is a leaflet that develops between primary leaflets.
60781	mesenchymal cell proliferation involved in prostate gland development	P	The multiplication or reproduction of mesenchymal cells, resulting in the expansion of a cell population that contributes to the progression of the prostate gland over time.
60782	regulation of mesenchymal cell proliferation involved in prostate gland development	P	Any process that modulates the frequency, rate or extent of mesenchymal cell proliferation that contributes to the progression of the prostate gland over time. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets.
60783	mesenchymal smoothened signaling pathway involved in prostate gland development	P	The series of molecular signals generated as a consequence of activation of the transmembrane Smoothened-type protein in the mesenchymal cells of the prostate that contribute to the progression of the prostate over time. This process contributes to lung development.
60784	regulation of cell proliferation involved in tissue homeostasis	P	Any process that modulates the frequency, rate or extent of cell proliferation resulting in the maintenance of a steady-state number of cells within a tissue.
60785	regulation of apoptosis involved in tissue homeostasis	P	Any process that modulates the occurrence or rate of cell death by apoptosis that results in the maintenance of the steady-state number of cells within a tissue.
60786	regulation of cell differentiation involved in tissue homeostasis	P	Any process that modulates the frequency, rate or extent of cell differentiation that contributes to the maintenance of a steady state of a cell type within a tissue.
60787	positive regulation of posterior neural plate formation by fibroblast growth factor receptor signaling pathway	P	Any process that increases the rate or extent of the formation of the posterior neural plate, the posterior end of the flat, thickened layer of ectodermal cells known as the neural plate.
60788	ectodermal placode formation	P	The developmental process in which an ectodermal placode forms. An ectodermal placode is a thickening of the ectoderm that is the primordium of many structures derived from the ectoderm.
60789	hair follicle placode formation	P	The developmental process in which a hair placode forms. An hair follicle placode is a thickening of the ectoderm that will give rise to the hair follicle bud.
60790	tooth placode formation	P	The developmental process in which the tooth placode forms. A tooth placode is a thickening of the ectoderm that will give rise to the tooth bud.
60791	sebaceous gland placode formation	P	The developmental process in which a sebaceous gland placode forms. A sebaceous gland placode is a thickening of the ectoderm that will give rise to the sebaceous gland bud.
60792	sweat gland development	P	The progression of the sweat gland over time, from its formation to the mature structure. Sweat glands secrete an aqueous solution that is used in thermoregulation.
60793	sweat gland placode formation	P	The developmental process in which the sweat gland placode forms. An sweat gland placode is a thickening of the ectoderm that will give rise to the sweat gland bud.
60794	leaflet morphogenesis	P	The process in which the anatomical structures of the leaflet are generated and organized.
60795	cell fate commitment involved in formation of primary germ layer	P	The commitment of cells to specific cell fates of the endoderm, ectoderm, or mesoderm as a part of gastrulation.
60796	regulation of transcription involved in primary germ layer cell fate commitment	P	Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that results in cells adopting an endoderm, ectoderm or mesoderm cell fate.
60797	transforming growth factor beta receptor signaling pathway involved in primary germ layer cell fate commitment	P	A series of molecular signals initiated by the binding of an extracellular ligand to a transforming growth factor beta receptor on the surface of a target cell, which contributes to an unspecified cell adopting a mesoderm fate.
60798	transforming growth factor beta receptor signaling pathway involved in mesodermal cell fate specification	P	The series of molecular signals generated as a consequence of a transforming growth factor beta receptor binding to one of its physiological ligands and ultimately resulting in the specification of a mesodermal fate.
60799	transforming growth factor beta receptor signaling pathway involved in endodermal cell fate specification	P	The series of molecular signals generated as a consequence of a transforming growth factor beta receptor binding to one of its physiological ligands and ultimately resulting in the commitment of an unspecified fate to adopt an endoderm fate.
60800	regulation of cell differentiation involved in embryonic placenta development	P	Any process that modulates the rate, frequency or extent of cell differentiation that contributes to the progression of the placenta over time, from its initial condition to its mature state.
60801	negative regulation of trophoblast cell differentiation by transforming growth factor beta signaling pathway	P	The transforming growth factor signaling process that decreases the rate, frequency, or extent of trophoblast stem cells differentiating into the more mature cells of the trophoblast.
60802	epiblast cell-extraembryonic ectoderm cell signaling involved in anterior/posterior axis specification	P	Any process that mediates the transfer of information from an epiblast cell to an extraembryonic ectoderm cell that contributes to the specification of the anterior/posterior axis.
60803	BMP signaling pathway involved in mesodermal cell fate specification	P	A series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, which contributes to a cell becoming specified to adopt a mesodermal fate.
60804	positive regulation of Wnt signaling pathway by BMP signaling pathway	P	A series of molecular signals generated as a consequence of any member of the BMP (bone morphogenetic protein) family binding to a cell surface receptor that results in an increase in the rate, frequency or extent of a Wnt signaling pathway.
60805	negative regulation of trophoblast cell differentiation by transcription regulation from RNA polymerase II promoter	P	Any process that modulates the rate, frequency or extent of transcription from an RNA polymerase II promoter ultimately resulting in a decrease in trophoblast stem cells differentiating into the more mature cells of the trophoblast.
60806	negative regulation of cell differentiation involved in embryonic placenta development	P	Any process that decreases the rate, frequency or extent of cell differentiation that contributes to the progression of the placenta over time, from its initial condition to its mature state.
60807	regulation of transcription from RNA polymerase II promoter involved in definitive endodermal cell fate specification	P	Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that ultimately results in a cell being specified to adopt a definitive endodermal cell fate.
60808	positive regulation of mesodermal to mesenchymal transition involved in gastrulation	P	Any process that increases the rate, frequency, or extent of epithelial to mesenchymal transition. Epithelial to mesenchymal transition where a mesodermal cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell as part of the process of gastrulation.
60809	mesodermal to mesenchymal transition involved in gastrulation	P	The epithelial to mesenchymal transition process in which a mesodermal cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell as part of the process of gastrulation.
60810	intracellular mRNA localization involved in pattern specification process	P	Any process in which mRNA is transported to, or maintained in, a specific location within an oocyte that results in a pattern being established in the embryo.
60811	intracellular mRNA localization involved in anterior/posterior axis specification	P	Any process in which mRNA is transported to, or maintained in, a specific location within the oocyte and/or syncytial embryo that contributes to the specification of the anterior/posterior axis.
60812	orthodenticle mRNA localization	P	Any process in which orthodenticle mRNA is transported to and maintained in the oocyte and/or syncytial embryo as part of the process that will specify the anterior/posterior axis.
60813	anterior mRNA localization involved in anterior/posterior axis specification	P	Any process in which a mRNA is transported to, and maintained in the anterior portion of the oocyte and/or syncytial embryo contributing to the specification of the anterior/posterior axis.
60814	posterior mRNA localization involved in anterior/posterior axis specification	P	Any process in which a mRNA is transported to and maintained in the oocyte and/or syncytial embryo contributing to the specification of the anterior/posterior axis.
60815	regulation of translation involved in anterior/posterior axis specification	P	Any process that modulates the frequency, rate or extent of translation of mRNAs that contribute to the specification of the anterior/posterior axis.
60816	random inactivation of X chromosome	P	Compensating for the two-fold variation in X-chromosome:autosome ratios between sexes by a global inactivation of all, or most of, the genes on either the paternal or maternal X-chromosome in the XX sex.
60817	inactivation of paternal X chromosome	P	Compensating for the two-fold variation in X-chromosome:autosome ratios between sexes by a global inactivation of all, or most of, the genes specifically on the paternal X-chromosome in the XX sex.
60818	inactivation of paternal X chromosome by genetic imprinting	P	Compensating for the two-fold variation in X-chromosome:autosome ratios between sexes by a global inactivation of all, or most of, the genes on the paternal X-chromosome in the XX sex by genetic imprinting.
60819	inactivation of X chromosome by genetic imprinting	P	Compensating for the two-fold variation in X-chromosome:autosome ratios between sexes by a global inactivation of all, or most of, the genes on one of the X-chromosomes in the XX sex by genetic imprinting.
60820	inactivation of X chromosome by heterochromatin assembly	P	Compensating for the two-fold variation in X-chromosome:autosome ratios between sexes by a global inactivation of all, or most of, the genes on one of the X-chromosomes in the XX sex by the mechanism of heterochromatin formation.
60821	inactivation of X chromosome by DNA methylation	P	Compensating for the two-fold variation in X-chromosome:autosome ratios between sexes by a global inactivation of all, or most of, the genes on one of the X-chromosomes in the XX sex by a mechanism of DNA methylation.
60822	transforming growth factor beta receptor signaling pathway involved in axial mesodermal cell fate specification	P	The series of molecular signals generated as a consequence of a transforming growth factor beta receptor binding to one of its physiological ligands and ultimately resulting in the specification of an axial mesodermal fate.
60823	canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation	P	The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes that contributes to the formation of the neural plate anterior/posterior pattern.
60824	retinoic acid receptor signaling pathway involved in neural plate anterior/posterior pattern formation	P	The series of molecular signals generated as a consequence of a retinoic acid receptor binding to one of its physiological ligands that contributes to the formation of the anterior/posterior pattern of the neural plate.
60825	fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation	P	The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands contributing to the anterior/posterior pattern of the neural plate.
60826	transforming growth factor beta receptor signaling pathway involved in neural plate anterior/posterior pattern formation	P	A series of molecular signals initiated by the binding of an extracellular ligand to a transforming growth factor beta receptor on the surface of a target cell, which contributes to the formation of the neural plate anterior/posterior pattern.
60827	regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation	P	Any process that modulates the rate, frequency, or extent of Wnt signaling through beta-catenin that results in the formation of the neural plate anterior/posterior pattern.
60828	regulation of canonical Wnt signaling pathway	P	Any process that modulates the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin, the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes.
60829	negative regulation of canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation	P	Any process that decreases the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin in the anterior end of the neural plate. This regulation sets up a Wnt signaling gradient along the anterior/posterior axis.
60830	ciliary receptor clustering involved in smoothened signaling pathway	P	Grouping of smoothened or patched receptors in a cilium, contributing to the smoothened signaling pathway.
60831	smoothened signaling pathway involved in dorsal/ventral neural tube patterning	P	The series of molecular signals generated as a consequence of activation of the transmembrane protein Smoothened contributing to the dorsal/ventral pattern of the neural tube.
60832	oocyte animal/vegetal axis specification	P	The establishment, maintenance and elaboration of the animal/vegetal axis in the oocyte. The animal/vegetal axis of an oocyte is defined by the placement of the nucleus in the oocyte and can sometimes be identified by the asymmetric placement of other substances such as yolk in the oocyte. The pole of the egg that is closest to the nucleus defines the animal end, with the axis passing through the nucleus.
60833	Wnt signaling pathway involved in animal/vegetal axis specification	P	The series of molecular signals initiated by binding of Wnt protein to a frizzled family receptor on the surface of the target cell contributing to the specification of the animal/vegetal axis of an oocyte.
60834	oral/aboral axis specification	P	The establishment, maintenance and elaboration of a line that delineates the mouth and the anus of an embryo.
60835	transforming growth factor receptor beta signaling pathway involved in oral/aboral axis specification	P	A series of molecular signals initiated by the binding of an extracellular ligand to a transforming growth factor beta receptor on the surface of a target cell, which contributes to the specification of the oral/aboral axis.
60836	lymphatic endothelial cell differentiation	P	The process in which a venous blood vessel endothelial cell acquires specialized features of a lymphatic vessel endothelial cell, a thin flattened cell that lines the inside surfaces of lymph vessels.
60837	blood vessel endothelial cell differentiation	P	The process in which a relatively unspecialized cell acquires specialized features of a blood vessel endothelial cell, a thin flattened cell that lines the inside surfaces of blood vessels.
60838	lymphatic endothelial cell fate commitment	P	The commitment of a venous blood vessel endothelial cell to a lymphatic endothelial cell fate and its capacity to differentiate into a lymphatic endothelial cell.
60839	endothelial cell fate commitment	P	The commitment of a cell to an endothelial cell fate and its capacity to differentiate into an endothelial cell.
60840	artery development	P	The progression of the artery over time, from its initial formation to the mature structure. An artery is a blood vessel that carries blood away from the heart to a capillary bed.
60841	venous blood vessel development	P	The progression of the venous blood vessel over time from its initial formation to the mature structure. Venous blood vessels carry blood back to the heart after the capillary bed.
60842	arterial endothelial cell differentiation	P	The process in which a relatively unspecialized endothelial cell acquires specialized features of an arterial endothelial cell, a thin flattened cell that lines the inside surfaces of arteries.
60843	venous endothelial cell differentiation	P	The process in which a relatively unspecialized endothelial cell acquires specialized features of a venous endothelial cell, a thin flattened cell that lines the inside surfaces of veins.
60844	arterial endothelial cell fate commitment	P	The commitment of a cell to an arterial endothelial cell fate and its capacity to differentiate into an arterial endothelial cell.
60845	venous endothelial cell fate commitment	P	The commitment of a cell to a venous endothelial cell fate and its capacity to differentiate into an venous endothelial cell.
60846	blood vessel endothelial cell fate commitment	P	The commitment of a cell to a blood vessel endothelial cell fate and its capacity to differentiate into a blood vessel endothelial cell.
60847	endothelial cell fate specification	P	The process involved in the specification of identity of an endothelial cell. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment.
60848	endothelial cell fate determination	P	A process involved in cell fate commitment of an endothelial cell. Once determination has taken place, a cell becomes committed to differentiate down a particular pathway regardless of its environment.
60849	regulation of transcription involved in lymphatic endothelial cell fate commitment	P	Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that contributes to the commitment of a venous endothelial cell to a lymphatic endothelial cell.
60850	regulation of transcription involved in cell fate commitment	P	Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that contributes to the commitment of a cell to a specific fate.
60851	vascular endothelial growth factor receptor signaling pathway involved in lymphatic endothelial cell fate commitment	P	The series of molecular signals generated as a consequence of vascular endothelial growth factor receptor binding to one of its physiological ligands that contributes to the commitment of a venous endothelial cell to a lymphatic endothelial cell fate.
60852	regulation of transcription involved in venous endothelial cell fate commitment	P	Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that contributes to the commitment of a cell to a specific fate and contributes to a cell adopting a venous endothelial cell fate.
60853	Notch signaling pathway involved in arterial endothelial cell fate commitment	P	The series of molecular signals initiated by binding of an extracellular ligand to a Notch receptor on the surface of the target cell and contributing to the commitment of a cell to an arterial endothelial cell fate.
60854	branching involved in lymph vessel morphogenesis	P	The process of the coordinated growth and sprouting of lymph vessels giving rise to the organized lymphatic system.
60855	venous endothelial cell migration involved in lymph vessel development	P	The orderly movement of venous endothelial cells out of the veins giving rise to the precursors of lymphatic endothelial cells.
60856	establishment of blood-brain barrier	P	Establishment of the barrier between the blood and the brain. The cells in the brain are packed tightly together preventing the passage of most molecules from the blood into the brain. Only lipid soluble molecules or those that are actively transported can pass through the blood-brain barrier.
60857	establishment of glial blood-brain barrier	P	Establishment of the glial barrier between the blood and the brain. The glial cells in the brain are packed tightly together preventing the passage of most molecules from the blood into the brain. Only lipid soluble molecules or those that are actively transported can pass through the blood-brain barrier.
60858	vesicle-mediated transport involved in floral organ abscission	P	The directed movement of substances within a cell by a cellular process that begins with the formation of membrane-bounded vesicles in which the transported substances are enclosed or located in the vesicle membrane which are then targeted to, and fuse with, an acceptor membrane contributing to the shedding of a floral organ.
60859	regulation of vesicle-mediated transport involved in floral organ abscission	P	Any process that modulates the rate, frequency, or extent of the directed movement of substances within a cell by a cellular process that begins with the formation of membrane-bounded vesicles in which the transported substances are enclosed or located in the vesicle membrane which are then targeted to, and fuse with, an acceptor membrane contributing to the shedding of a floral organ.
60860	regulation of floral organ abscission	P	Any process that modulates the rate, frequency, or extent of floral organ abscission, the controlled shedding of floral organs.
60861	positive regulation of floral organ abscission	P	Any process that increases the rate, frequency, or extent of floral organ shedding, the controlled shedding of floral organs.
60862	negative regulation of floral organ abscission	P	Any process that decreases the rate, frequency, or extent of floral organ abscission, the controlled shedding of floral organs.
60863	regulation of floral organ abscission by signal transduction	P	The cascade of processes by which a signal interacts with a receptor, causing a change in the level or activity of a second messenger or other downstream target, and ultimately modulating the rate, or extent of floral organ abscission.
60864	positive regulation of floral organ abscission by small GTPase mediated signal transduction	P	Any series of molecular signals in which a small monomeric GTPase relays one or more of the signals that increases the rate or extent of floral organ abscission.
60865	negative regulation of floral organ abscission by transmembrane receptor protein serine/threonine kinase signaling pathway	P	The series of molecular signals generated as a consequence of a transmembrane receptor serine/threonine kinase binding to its physiological ligand and contributing to the decrease in the rate or frequency of floral organ abscission.
60866	leaf abscission	P	The controlled shedding of a leaf.
60867	fruit abscission	P	The controlled shedding of a fruit.
60868	regulation of vesicle-mediated transport involved in floral organ abscission by small GTPase mediated signal transduction	P	Any series of molecular signals in which a small monomeric GTPase relays one or more of the signals that modulates the rate or extent of floral organ abscission.
60869	transmembrane receptor protein serine/threonine kinase signaling pathway involved in floral organ abscission	P	A series of molecular signals initiated by the binding of an extracellular ligand to a receptor on the surface of the target cell where the receptor possesses serine/threonine kinase activity, which contributes to the process of floral organ abscission.
60870	cell wall disassembly involved in floral organ abscission	P	A cellular process that results in the breakdown of the cell wall that contributes to the process of floral organ abscission.
60872	semicircular canal development	P	The progression of the semicircular canal from its initial formation to the mature structure.
60873	anterior semicircular canal development	P	The progession of the anterior semicircular canal from its initial formation to the mature structure.
60874	posterior semicircular canal development	P	The progession of the posterior semicircular canal from its initial formation to the mature structure.
60875	lateral semicircular canal development	P	The progession of the lateral semicircular canal from its initial formation to the mature structure.
60876	semicircular canal formation	P	The developmental process pertaining to the initial formation of the semicircular canal from the otic vesicle. This process begins with the regionalization of the vesicle that specifies the area where the vesicles will form and continues through the process of fusion which forms the initial tubes.
60877	regionalization involved in semicircular canal formation	P	The pattern specification process that results in the subdivision of the otic epithelium in space to define an area or volume in which cells will differentiate to give rise to the semicircular canals.
60878	pouch outgrowth involved in semicircular canal formation	P	The morphogenetic process in which an epithelial sheet bends along a linear axis and gives rise to a pouch that will form a semicircular canal.
60879	semicircular canal fusion	P	Creation of the central hole of the semicircular canal by sealing the edges of the pouch that forms ruing the process of semicircular canal formation.
60880	cell morphogenesis involved in semicircular canal fusion	P	The change in form (cell shape and size) that occurs when a semicircular canal epithelial cell acquires the structural features that allow it to contribute to the process of semicircular canal fusion.
60881	basal lamina disassembly	P	A process that results in the breakdown of the basal lamina.
60882	basal lamina disassembly involved in semicircular canal fusion	P	A process that results in the breakdown of the basal lamina that contributes to the process of semicircular canal fusion.
60883	regulation of basal lamina disassembly involved in semicircular canal fusion by cell communication	P	Any process that mediates interactions between a cell and its surroundings that modulates of the rate, frequency or extent of basal lamina disassembly involved in semicircular canal fusion.
60884	clearance of cells from fusion plate	P	The morphogenetic process in which cells are removed from the inner loop of a semicircular canal.
60885	clearance of cells from fusion plate by apoptotic process	P	Any apoptotic process that contributes to the shaping of the semicircular canal by removing cells in the fusion plate, forming the loops of the canals.
60886	clearance of cells from fusion plate by epithelial to mesenchymal transition	P	The process of epithelial to mesenchymal transition that contributes to the shaping of the semicircular canal by effectively removing epithelial cells from the fusion plate, forming the loops of the canals.
60887	limb epidermis development	P	The process whose specific outcome is the progression of the epidermis of the limb over time, from its formation to the mature structure. The limb epidermis is the outer epithelial layer of the limb, it is a complex stratified squamous epithelium.
60888	limb epidermis stratification	P	The pattern specification process that results in the subdivision of the epidermis of the limb in space to define a volume in which specific patterns of basal cell, spinous cell and granular cells will differentiate giving rise to the layers of the limb epidermis.
60889	limb basal epidermal cell differentiation	P	The process in which a relatively unspecialized cell acquires specialized features of a limb epidermal basal cell. A epidermal basal cell cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into more specialized cell of the limb epidermis.
60890	limb spinous cell differentiation	P	The process in which a relatively unspecialized cell acquires specialized features of a limb epidermal spinous cell.
60891	limb granular cell differentiation	P	The process in which a relatively unspecialized cell acquires specialized features of a limb epidermal granular cell.
60892	limb basal epidermal cell fate specification	P	The process in which a cell becomes capable of differentiating autonomously into an limb basal epidermal cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.
60893	limb granular cell fate specification	P	The process in which a cell becomes capable of differentiating autonomously into an limb granular cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.
60894	limb spinous cell fate specification	P	The process in which a cell becomes capable of differentiating autonomously into a limb spinous cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.
60895	retinoic acid receptor signaling pathway involved in spinal cord dorsal/ventral patterning	P	The series of molecular signals generated as a consequence of a retinoic acid receptor binding to one of its physiological ligands that contributes to the dorsal ventral patterning of the spinal cord.
60896	neural plate pattern specification	P	The developmental process that results in the creation of defined areas or spaces within the neural plate to which cells respond and eventually are instructed to differentiate.
60897	neural plate regionalization	P	The pattern specification process that results in the subdivision of an axis or axes of the neural plate in space to define an area or volume in which specific patterns of cell differentiation will take place or in which cells interpret a specific environment.
60898	eye field cell fate commitment involved in camera-type eye formation	P	The commitment of neurectodermal cells to cells of the eye field and their capacity to differentiate into eye field cells. Eye field cells are neurectodermal cells that will form the optic placode.
60899	regulation of transcription involved in eye field cell fate commitment of camera-type eye	P	Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that contributes to the commitment of a neurectodermal cell to a specialized neurectodermal cell that will give rise to the optic vesicle.
60900	embryonic camera-type eye formation	P	The developmental process pertaining to the initial formation of a camera-type eye from unspecified neurectoderm. This process begins with the differentiation of cells that form the optic field and ends when the optic cup has attained its shape.
60901	regulation of hair cycle by canonical Wnt signaling pathway	P	The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes that modulates the rate, frequency or extent of the hair cycle.
60902	regulation of hair cycle by BMP signaling pathway	P	A series of molecular signals generated as a consequence of any member of the BMP (bone morphogenetic protein) family binding to a cell surface receptor that modulates the rate, frequency or extent of the hair cycle.
60903	positive regulation of meiosis I	P	Any process that increases the rate, frequency, or extent of meiosis I, a cell cycle process comprising the steps by which a cell progresses through the first phase of meiosis, in which cells divide and homologous chromosomes are paired and segregated from each other, producing two daughter cells.
60904	regulation of protein folding in endoplasmic reticulum	P	Any process that modulates the rate, frequency or extent of the protein folding process that takes place in the endoplasmic reticulum (ER). Secreted, plasma membrane and organelle proteins are folded in the ER, assisted by chaperones and foldases (protein disulphide isomerases), and additional factors required for optimal folding (ATP, Ca2+ and an oxidizing environment to allow disulfide bond formation).
60905	regulation of induction of conjugation upon nitrogen starvation	P	Any process that modulates the frequency of induction of conjugation upon nitrogen starvation, the process in which a cell initiates conjugation with cellular fusion upon nitrogen starvation.
60906	negative regulation of chromatin silencing by small RNA	P	Any process that decreases the frequency, rate or extent of chromatin silencing by small RNA. Chromatin silencing by small RNA is the repression of transcription by conversion of large regions of DNA into heterochromatin, directed by small RNAs sharing sequence identity to the repressed region.
60907	positive regulation of macrophage cytokine production	P	Any process that increases the rate, frequency or extent of macrophage cytokine production. Macrophage cytokine production is the appearance of a chemokine due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
60908	plasmid copy number maintenance	P	The maintenance of the number of copies of extrachromosomal plasmid DNA.
60909	regulation of DNA replication initiation involved in plasmid copy number maintenance	P	Any process that modulates the frequency, rate or extent of initiation of plasmid DNA replication that contributes to copy number maintenance.
60910	negative regulation of DNA replication initiation involved in plasmid copy number maintenance	P	Any process that decreases the frequency, rate or extent of initiation of plasmid DNA replication that contributes to copy number maintenance.
60911	cardiac cell fate commitment	P	The commitment of cells to specific cardiac cell fates and their capacity to differentiate into cardiac cells. Cardiac cells are cells that comprise the organ which pumps blood through the circulatory system.
60912	cardiac cell fate specification	P	The process involved in the specification of cardiac cell identity. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment.
60913	cardiac cell fate determination	P	The process involved in cardiac cell fate commitment. Once determination has taken place, a cell becomes committed to differentiate down a particular pathway regardless of its environment.
60914	heart formation	P	The developmental process pertaining to the initial formation of the heart from unspecified parts. This process begins with the specific processes that contribute to the appearance of the heart field and the arrival of cardiac neural crest to the heart region. The process ends when the structural rudiment is recognizable.
60915	mesenchymal cell differentiation involved in lung development	P	The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal cell of the lung. A mesenchymal cell is a loosely associated cell that is part of the connective tissue in an organism. Mesenchymal cells give rise to more mature connective tissue cell types.
60916	mesenchymal cell proliferation involved in lung development	P	The multiplication or reproduction of cells, resulting in the expansion of a mesenchymal cell population that contributes to the progression of the lung over time. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets.
60917	regulation of (1->6)-beta-D-glucan biosynthetic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of (1->6)-beta-D-glucans.
60918	auxin transport	P	The directed movement of auxin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
60919	auxin influx	P	The process involved in the transport of auxin into the cell.
60920	cardiac pacemaker cell differentiation	P	The process in which a relatively unspecialized cell acquires specialized features of a pacemaker cell. Pacemaker cells are specialized cardiomyocytes that are responsible for regulating the timing of heart contractions.
60921	sinoatrial node cell differentiation	P	The process in which a relatively unspecialized cell acquires specialized features of a sinoatrial (SA) node cell. SA node cells are pacemaker cells that are found in the sinoatrial node.
60922	atrioventricular node cell differentiation	P	The process in which a relatively unspecialized cell acquires specialized features of an atrioventricular (AV) node cell. AV node cells are pacemaker cells that are found in the atrioventricular node.
60923	cardiac muscle cell fate commitment	P	The commitment of cells to specific cardiac muscle cell fates and their capacity to differentiate into cardiac muscle cells. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction.
60924	atrial cardiac muscle cell fate commitment	P	The commitment of cells to atrial cardiac muscle cell fates and their capacity to differentiate into cardiac muscle cells of the atrium. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction.
60925	ventricular cardiac muscle cell fate commitment	P	The commitment of cells to ventricular cardiac muscle cell fates and their capacity to differentiate into cardiac muscle cells of the ventricle. Cardiac muscle cells are striated muscle cells that are responsible for heart contraction.
60926	cardiac pacemaker cell development	P	The process whose specific outcome is the progression of a pacemaker cell over time, from its formation to the mature state. Pacemaker cells are specialized cardiomyocytes that are responsible for regulating the timing of heart contractions.
60927	cardiac pacemaker cell fate commitment	P	The commitment of cells to pacemaker cell fates and their capacity to differentiate into pacemaker cells. Pacemaker cells are specialized cardiomyocytes that are responsible for regulating the timing of heart contractions.
60928	atrioventricular node cell development	P	The process whose specific outcome is the progression of an atrioventricular (AV) node cell over time, from its formation to the mature state.
60929	atrioventricular node cell fate commitment	P	The commitment of cells to atrioventricular (AV) node cell fates and their capacity to differentiate into AV node cells.
60930	sinoatrial node cell fate commitment	P	The commitment of cells to sinoatrial (SA) node cell fates and their capacity to differentiate into SA node cells. SA node cells are pacemaker cells that are found in the sinoatrial node.
60931	sinoatrial node cell development	P	The process whose specific outcome is the progression of a sinoatrial (SA) node cell over time, from its formation to the mature state. SA node cells are pacemaker cells that are found in the sinoatrial node.
60932	His-Purkinje system cell differentiation	P	The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cell of the His-Purkinje system. These cells form the fibers regulate cardiac muscle contraction in the ventricles.
60933	His-Purkinje system cell development	P	The process whose specific outcome is the progression of a His-Purkinje cell over time, from its formation to the mature state. These cells form the fibers that regulate cardiac muscle contraction in the ventricles.
60934	His-Purkinje system cell fate commitment	P	The commitment of cells to His-Purkinje cell fates and their capacity to differentiate into His-Purkinje cells. These cells form the fibers that regulate cardiac muscle contraction in the ventricles.
60935	cardiac fibroblast cell differentiation	P	The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a cardiac fibroblast. A cardiac fibroblast is a connective tissue cell in the heart which secretes an extracellular matrix rich in collagen and other macromolecules.
60936	cardiac fibroblast cell development	P	The process whose specific outcome is the progression of a cardiac fibroblast over time, from its formation to the mature state. A cardiac fibroblast is a connective tissue cell of the heart which secretes an extracellular matrix rich in collagen and other macromolecules.
60937	cardiac fibroblast cell fate commitment	P	The commitment of cells to a cardiac fibroblast fate and their capacity to differentiate into cardiac fibroblast cells. A cardiac fibroblast is a connective tissue cell in the heart which secretes an extracellular matrix rich in collagen and other macromolecules.
60938	epicardium-derived cardiac fibroblast cell differentiation	P	The process in which an epicardial cell acquires the specialized structural and/or functional features of a cardiac fibroblast. A cardiac fibroblast is a connective tissue cell in the heart which secretes an extracellular matrix rich in collagen and other macromolecules.
60939	epicardium-derived cardiac fibroblast cell development	P	The process whose specific outcome is the progression of an epicardial-derived cardiac fibroblast over time, from its formation to the mature state. A epicardial-derived cardiac fibroblast is a connective tissue cell of the heart that arises from the epicardium and secretes an extracellular matrix rich in collagen and other macromolecules.
60940	epithelial to mesenchymal transition involved in cardiac fibroblast development	P	A transition where an epicardial cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell that will mature into a cardiac fibroblast.
60941	epicardium-derived cardiac fibroblast cell fate commitment	P	The commitment of an epicardial cell to a cardiac fibroblast cell fate and its capacity to differentiate into a cardiac fibroblast. A cardiac fibroblast is a connective tissue cell in the heart which secretes an extracellular matrix rich in collagen and other macromolecules.
60942	neural crest-derived cardiac fibroblast cell differentiation	P	The process in which a neural crest cell acquires the specialized structural and/or functional features of a cardiac fibroblast. A cardiac fibroblast is a connective tissue cell in the heart which secretes an extracellular matrix rich in collagen and other macromolecules.
60943	neural crest-derived cardiac fibroblast cell development	P	The process whose specific outcome is the progression of a cardiac fibroblast over time, from its formation from a neural crest cell to the mature state. A cardiac fibroblast is a connective tissue cell of the heart which secretes an extracellular matrix rich in collagen and other macromolecules.
60944	neural crest-derived cardiac fibroblast cell fate commitment	P	The commitment of neural crest cells to a cardiac fibroblast fate and their capacity to differentiate into cardiac fibroblast cells. A cardiac fibroblast is a connective tissue cell in the heart which secretes an extracellular matrix rich in collagen and other macromolecules.
60945	cardiac neuron differentiation	P	The process in which a relatively unspecialized cell acquires specialized features of a neuron of the heart.
60946	cardiac blood vessel endothelial cell differentiation	P	The process in which a relatively unspecialized cell acquires specialized features of a blood vessel endothelial cell of the heart. Blood vessel endothelial cells are thin flattened cells that line the inside surfaces of blood vessels.
60947	cardiac vascular smooth muscle cell differentiation	P	The process in which a relatively unspecialized cell acquires specialized features of a cardiac vascular smooth muscle cell. A cardiac vascular smooth muscle cell covers the heart vasculature and lacks transverse striations in its constituent fibers.
60948	cardiac vascular smooth muscle cell development	P	The process whose specific outcome is the progression of a cardiac vascular smooth muscle cell over time, from its formation to the mature state.
60949	cardiac vascular smooth muscle cell fate commitment	P	The commitment of cells to a cardiac vascular smooth muscle cell fate and its capacity to differentiate into a cardiac vascular smooth muscle cell.
60950	cardiac glial cell differentiation	P	The process in which a relatively unspecialized cell acquires the specialized features of a glial cell of the heart.
60951	neural crest-derived cardiac glial cell differentiation	P	The process in which a neural crest cell acquires the specialized features of a glial cell of the heart.
60952	cardiac glial cell development	P	The process aimed at the progression of a cardiac glial cell over time, from its formation to the fully functional mature cell.
60953	cardiac glial cell fate commitment	P	The commitment of cells to cardiac glial cell fates and their capacity to differentiate into cardiac glial cells.
60954	neural crest-derived cardiac glial cell development	P	The process aimed at the progression of a neural crest-derived cardiac glial cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.
60955	neural crest-derived cardiac glial cell fate commitment	P	The commitment of neural crest cells to cardiac glial cell fates and their capacity to differentiate into cardiac glial cells.
60956	endocardial cell differentiation	P	The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of an endocardial cell. An endocardial cell is a specialized endothelial cell that makes up the endocardium portion of the heart. The endocardium is the innermost layer of tissue of the heart, and lines the heart chambers.
60957	endocardial cell fate commitment	P	The commitment of a cell to an endocardial cell fate and its capacity to differentiate into an endocardial cell. An endocardial cell is a specialized endothelial cell that makes up the endocardium portion of the heart.
60958	endocardial cell development	P	The progression of an endocardial cell over time, from its formation to the mature cell. An endocardial cell is a specialized endothelial cell that makes up the endocardium portion of the heart.
60959	cardiac neuron development	P	The process whose specific outcome is the progression of a cardiac neuron over time, from its formation to the mature state.
60960	cardiac neuron fate commitment	P	The process in which the developmental fate of a cell becomes restricted such that it will develop into a neuron of the heart.
60961	phospholipase D inhibitor activity	F	Stops, prevents or reduces the activity of a phospholipase D, an enzyme that catalyzes the reaction: a phosphatidylcholine + H2O = choline + a phosphatidate.
60962	regulation of ribosomal protein gene transcription from RNA polymerase II promoter	P	Any process that modulates the frequency, rate or extent of the synthesis of RNA from ribosomal protein genes by RNA polymerase II, originating at an RNA polymerase II promoter.
60963	positive regulation of ribosomal protein gene transcription from RNA polymerase II promoter	P	Any process that increases the frequency, rate or extent of the synthesis of RNA from ribosomal protein genes by RNA polymerase II, originating at an RNA polymerase II promoter.
60964	regulation of gene silencing by miRNA	P	Any process that modulates the rate, frequency, or extent of the downregulation of gene expression through the action of microRNAs (miRNAs), endogenous 21-24 nucleotide small RNAs processed from stem-loop RNA precursors (pre-miRNAs). Once incorporated into a RNA-induced silencing complex (RISC), miRNAs can downregulate gene expression by either of two posttranscriptional mechanisms: mRNA cleavage or translational repression.
60965	negative regulation of gene silencing by miRNA	P	Any process that decreases the rate, frequency, or extent of the downregulation of gene expression through the action of microRNAs (miRNAs), endogenous 21-24 nucleotide small RNAs processed from stem-loop RNA precursors (pre-miRNAs). Once incorporated into a RNA-induced silencing complex (RISC), miRNAs can downregulate gene expression by either of two posttranscriptional mechanisms: mRNA cleavage or translational repression.
60966	regulation of gene silencing by RNA	P	Any process that regulates the rate, frequency, or extent of gene silencing by RNA. Gene silencing by RNA is the process in which RNA molecules inactivate expression of target genes.
60967	negative regulation of gene silencing by RNA	P	Any process that decreases the rate, frequency, or extent of gene silencing by RNA. Gene silencing by RNA is the process in which RNA molecules inactivate expression of target genes.
60968	regulation of gene silencing	P	Any process that modulates the rate, frequency, or extent of gene silencing, the transcriptional or post-transcriptional process carried out at the cellular level that results in long-term gene inactivation.
60969	negative regulation of gene silencing	P	Any process that decreases the rate, frequency, or extent of gene silencing, the transcriptional or post-transcriptional process carried out at the cellular level that results in long-term gene inactivation.
60970	embryonic heart tube dorsal/ventral pattern formation	P	The regionalization process in which the areas along the dorsal/ventral axis of the embryonic heart tube are established. This process will determine the patterns of cell differentiation along the axis.
60971	embryonic heart tube left/right pattern formation	P	The pattern specification process that results in the subdivision of the left/right axis of the embryonic heart tube in space to define an area or volume in which specific patterns of cell differentiation will take place.
60972	left/right pattern formation	P	The pattern specification process that results in the subdivision of the left/right axis in space to define an area or volume in which specific patterns of cell differentiation will take place or in which cells interpret a specific environment.
60973	cell migration involved in heart development	P	The orderly movement of a cell from one site to another that will contribute to the progression of the heart over time, from its initial formation, to the mature organ.
60974	cell migration involved in heart formation	P	The orderly movement of a cell from one site to another that contribute to the formation of the heart. The initial heart structure is made up of mesoderm-derived heart progenitor cells and neural crest-derived cells.
60975	cardioblast migration to the midline involved in heart field formation	P	The orderly movement of a cardioblast toward the midline to form the heart field. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating.
60976	coronary vasculature development	P	The process whose specific outcome is the progression of the blood vessels of the heart over time, from its formation to the mature structure.
60977	coronary vasculature morphogenesis	P	The process in which the anatomical structures of blood vessels of the heart are generated and organized. The blood vessel is the vasculature carrying blood.
60978	angiogenesis involved in coronary vascular morphogenesis	P	Blood vessel formation in the heart when new vessels emerge from the proliferation of pre-existing blood vessels.
60979	vasculogenesis involved in coronary vascular morphogenesis	P	The differentiation of endothelial cells from progenitor cells that contributes to blood vessel development in the heart, and the de novo formation of blood vessels and tubes.
60980	cell migration involved in coronary vasculogenesis	P	The orderly movement of a cell from one site to another that will contribute to the differentiation of an endothelial cell that will form the blood vessels of the heart.
60981	cell migration involved in coronary angiogenesis	P	The orderly movement of a cell from one site to another that will contribute to the formation of new blood vessels in the heart from pre-existing blood vessels.
60982	coronary artery morphogenesis	P	The process in which the anatomical structures of coronary arteries are generated and organized. Coronary arteries are blood vessels that transport blood to the heart muscle.
60983	epicardium-derived cardiac vascular smooth muscle cell differentiation	P	The process in which a relatively unspecialized cell derived from the epicardium acquires specialized features of a cardiac vascular smooth muscle cell. A cardiac vascular smooth muscle cell covers the heart vasculature and lacks transverse striations in its constituent fibers.
60984	epicardium-derived cardiac vascular smooth muscle cell development	P	The process whose specific outcome is the progression of a cardiac vascular smooth muscle cell that was derived from the epicardium over time, from its formation to the mature state.
60985	epicardium-derived cardiac vascular smooth muscle cell fate commitment	P	The commitment of an epicardial cell to a cardiac vascular smooth muscle cell fate and its capacity to differentiate into a cardiac vascular smooth muscle cell.
60986	endocrine hormone secretion	P	The regulated release of a hormone into the circulatory system.
60987	lipid tube	C	A macromolecular complex that contains a tube of lipid surrounded by a protein coat.
60988	lipid tube assembly	P	The aggregation, arrangement and bonding together of a set of macromolecules to form a macromolecular complex that contains a tube of lipid surrounded by a protein coat involved in membrane shaping of vesicle membranes as they fuse or undergo fission.
60989	lipid tube assembly involved in organelle fusion	P	The aggregation, arrangement and bonding together of a set of macromolecules to form a macromolecular complex that contains a tube of lipid surrounded by a protein coat involved in membrane shaping of vesicle membranes as organelles fuse.
60990	lipid tube assembly involved in organelle fission	P	The aggregation, arrangement and bonding together of a set of macromolecules to form a macromolecular complex that contains a tube of lipid surrounded by a protein coat involved in membrane shaping of vesicle membranes as organelles undergo fission.
60992	response to fungicide	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fungicide stimulus. Fungicides are chemicals used to kill fungi.
60993	kidney morphogenesis	P	Morphogenesis of a kidney. A kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine.
60994	regulation of transcription from RNA polymerase II promoter involved in kidney development	P	Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that contributes to the branching morphogenesis by which the kidney progresses from its initial formation to the mature state.
60995	cell-cell signaling involved in kidney development	P	Any process that mediates the transfer of information from one cell to another and contributes to the progression of the kidney over time, from its formation to the mature organ.
60996	dendritic spine development	P	The process whose specific outcome is the progression of the dendritic spine over time, from its formation to the mature structure. A dendritic spine is a protrusion from a dendrite and a specialized subcellular compartment involved in synaptic transmission.
60997	dendritic spine morphogenesis	P	The process in which the anatomical structures of a dendritic spine are generated and organized. A dendritic spine is a protrusion from a dendrite and a specialized subcellular compartment involved in synaptic transmission.
60998	regulation of dendritic spine development	P	Any process that modulates the rate, frequency, or extent of dendritic spine development, the process whose specific outcome is the progression of the dendritic spine over time, from its formation to the mature structure.
60999	positive regulation of dendritic spine development	P	Any process that increases the rate, frequency, or extent of dendritic spine development, the process whose specific outcome is the progression of the dendritic spine over time, from its formation to the mature structure.
61000	negative regulation of dendritic spine development	P	Any process that decreases the rate, frequency, or extent of dendritic spine development, the process whose specific outcome is the progression of the dendritic spine over time, from its formation to the mature structure.
61001	regulation of dendritic spine morphogenesis	P	Any process that modulates the rate, frequency, or extent of dendritic spine morphogenesis, the process in which the anatomical structures of a dendritic spine are generated and organized. A dendritic spine is a protrusion from a dendrite and a specialized subcellular compartment involved in synaptic transmission.
61002	negative regulation of dendritic spine morphogenesis	P	Any process that decreases the rate, frequency, or extent of dendritic spine morphogenesis, the process in which the anatomical structures of a dendritic spine are generated and organized. A dendritic spine is a protrusion from a dendrite and a specialized subcellular compartment involved in synaptic transmission.
61003	positive regulation of dendritic spine morphogenesis	P	Any process that increases the rate, frequency, or extent of dendritic spine morphogenesis, the process in which the anatomical structures of a dendritic spine are generated and organized. A dendritic spine is a protrusion from a dendrite and a specialized subcellular compartment involved in synaptic transmission.
61004	pattern specification involved in kidney development	P	Any developmental process that results in the creation of defined areas or spaces within the kidney to which cells respond and eventually are instructed to differentiate.
61005	cell differentiation involved in kidney development	P	The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the kidney as it progresses from its formation to the mature state.
61006	regulation of cell proliferation involved in kidney morphogenesis	P	Any process that modulates the frequency, rate or extent of cell proliferation that contributes to the shaping of the kidney.
61007	hepaticobiliary system process	P	An system process carried out by any of the organs or tissues of the hepaticobiliary system. The hepaticobiliary system is responsible for metabolic and catabolic processing of small molecules absorbed from the blood or gut, hormones and serum proteins, detoxification, storage of glycogen, triglycerides, metals and lipid soluble vitamins and excretion of bile. Included are the synthesis of albumin, blood coagulation factors, complement, and specific binding proteins.
61008	hepaticobiliary system development	P	The progression of the hepaticobiliary system over time, from its formation to the mature structure. The hepaticobiliary system is responsible for metabolic and catabolic processing of small molecules absorbed from the blood or gut, hormones and serum proteins, detoxification, storage of glycogen, triglycerides, metals and lipid soluble vitamins and excretion of bile. Included are the synthesis of albumin, blood coagulation factors, complement, and specific binding proteins.
61009	common bile duct development	P	The progression of the common bile duct over time, from its formation to the mature structure. The common bile duct is formed from the joining of the common hepatic duct running from the liver, and the cystic duct running from the gall bladder. The common bile duct transports bile from the liver and gall bladder to the intestine.
61010	gall bladder development	P	The progression of the gall bladder over time, from its initial formation to the mature structure. The gall bladder is a cavitated organ that stores bile.
61011	hepatic duct development	P	The progression of the hepatic duct over time, from its formation to the mature structure. The hepatic duct is the duct that leads from the liver to the common bile duct.
61013	regulation of mRNA catabolic process	P	Any process that modulates the rate, frequency, or extent of a mRNA catabolic process, the chemical reactions and pathways resulting in the breakdown of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage.
61014	positive regulation of mRNA catabolic process	P	Any process that increases the rate, frequency, or extent of a mRNA catabolic process, the chemical reactions and pathways resulting in the breakdown of RNA, ribonucleic acid, one of the two main type of nucleic acid, consisting of a long, unbranched macromolecule formed from ribonucleotides joined in 3',5'-phosphodiester linkage.
61015	snRNA import into nucleus	P	The directed movement of snRNA, small nuclear ribonucleic acid into the nucleus.
61016	snRNA import into Cajal body	P	The directed movement of snRNA, small nuclear ribonucleic acid, into a Cajal body.
61017	hepatoblast differentiation	P	The process in which a relatively unspecialized cell acquires specialized features of a hepatoblast. A hepatoblast is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into hepatocytes and cholangiocytes.
61024	membrane organization	P	A process which results in the assembly, arrangement of constituent parts, or disassembly of a membrane. A membrane is a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.
61025	membrane fusion	P	The membrane organization process that joins two lipid bilayers to form a single membrane.
61026	cardiac muscle tissue regeneration	P	The regrowth of cardiac muscle tissue to repair injured or damaged muscle fibers in the postnatal stage.
61027	umbilical cord development	P	The process whose specific outcome is the development of the umbilical cord, from its formation to the mature structure. The umbilical cord is an organ or embryonic origin consisting of the 2 umbilical arteries and the one umbilical vein. The umbilical cord connects the cardiovascular system of the fetus to the mother via the placenta.
61028	establishment of endothelial barrier	P	The establishment of a barrier between endothelial cell layers, such as those in the brain, lung or intestine, to exert specific and selective control over the passage of water and solutes, thus allowing formation and maintenance of compartments that differ in fluid and solute composition.
61029	eyelid development in camera-type eye	P	The progression of the eyelid in a camera-type eye from its formation to the mature state. The eyelid is a membranous cover that helps protect and lubricate the eye.
61030	epithelial cell differentiation involved in mammary gland alveolus development	P	The process in which a relatively unspecialized epithelial cell becomes a more specialized epithelial cell of the mammary gland alveolus.
61031	endodermal digestive tract morphogenesis	P	The process in which the anatomical structures of the endodermal digestive tract are generated and organized. The endodermal digestive tract includes those portions of the digestive tract that are derived from endoderm.
61032	visceral serous pericardium development	P	The progression of the visceral serous pericardium from its formation to the mature structure. The visceral serous pericardium is the inner layer of the pericardium.
61033	secretion by lung epithelial cell involved in lung growth	P	The controlled release of liquid by a lung epithelial cell that contributes to an increase in size of the lung as part of its development.
61034	olfactory bulb mitral cell layer development	P	The progression of the olfactory bulb mitral cell layer over time from its initial formation until its mature state. The mitral cell layer is composed of pyramidal neurons whose cell bodies are located between the granule cell layer and the plexiform layer.
61035	regulation of cartilage development	P	Any process that modulates the rate, frequency, or extent of cartilage development, the process whose specific outcome is the progression of the cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate.
61036	positive regulation of cartilage development	P	Any process that increases the rate, frequency, or extent of cartilage development, the process whose specific outcome is the progression of the cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate.
61037	negative regulation of cartilage development	P	Any process that decreases the rate, frequency, or extent of cartilage development, the process whose specific outcome is the progression of the cartilage over time, from its formation to the mature structure. Cartilage is a connective tissue dominated by extracellular matrix containing collagen type II and large amounts of proteoglycan, particularly chondroitin sulfate.
61038	uterus morphogenesis	P	The process in which anatomical structures of the uterus are generated and organized.
61040	female gonad morphogenesis	P	The process in which a female gonad is generated and organized.
61041	regulation of wound healing	P	Any process that modulates the rate, frequency, or extent of the series of events that restore integrity to a damaged tissue, following an injury.
61042	vascular wound healing	P	Blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels and contribute to the series of events that restore integrity to damaged vasculature.
61043	regulation of vascular wound healing	P	Any process that modulates the rate, frequency, or extent of blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels and contribute to the series of events that restore integrity to damaged vasculature.
61044	negative regulation of vascular wound healing	P	Any process that decreases the rate, frequency, or extent of blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels and contribute to the series of events that restore integrity to damaged vasculature.
61045	negative regulation of wound healing	P	Any process that decreases the rate, frequency, or extent of the series of events that restore integrity to a damaged tissue, following an injury.
61046	regulation of branching involved in lung morphogenesis	P	Any process that modulates the rate, frequency, or extent of the process in which a highly ordered sequence of patterning events generates the branched structures of the lung, consisting of reiterated combinations of bud outgrowth, elongation, and dichotomous subdivision of terminal units.
61047	positive regulation of branching involved in lung morphogenesis	P	Any process that increases the rate, frequency, or extent of the process in which a highly ordered sequence of patterning events generates the branched structures of the lung, consisting of reiterated combinations of bud outgrowth, elongation, and dichotomous subdivision of terminal units.
61048	negative regulation of branching involved in lung morphogenesis	P	Any process that decreases the rate, frequency, or extent of the process in which a highly ordered sequence of patterning events generates the branched structures of the lung, consisting of reiterated combinations of bud outgrowth, elongation, and dichotomous subdivision of terminal units.
61049	cell growth involved in cardiac muscle cell development	P	The growth of a cardiac muscle cell, where growth contributes to the progression of the cell over time from its initial formation to its mature state.
61050	regulation of cell growth involved in cardiac muscle cell development	P	Any process that modulates the rate, frequency, or extent of the growth of a cardiac muscle cell, where growth contributes to the progression of the cell over time from its initial formation to its mature state.
61051	positive regulation of cell growth involved in cardiac muscle cell development	P	Any process that increases the rate, frequency, or extent of the growth of a cardiac muscle cell, where growth contributes to the progression of the cell over time from its initial formation to its mature state.
61052	negative regulation of cell growth involved in cardiac muscle cell development	P	Any process that decreases the rate, frequency, or extent of the growth of a cardiac muscle cell, where growth contributes to the progression of the cell over time from its initial formation to its mature state.
61053	somite development	P	The progression of a somite from its initial formation to the mature structure. Somites are mesodermal clusters that are arranged segmentally along the anterior posterior axis of an embryo.
61054	dermatome development	P	The progression of the dermatome over time, from its initial formation to the mature structure. The dermatome is the portion of a somite that will form skin.
61055	myotome development	P	The progression of the myotome over time, from its formation to the mature structure. The myotome is the portion of the somite that will give rise to muscle.
61056	sclerotome development	P	The progression of the sclerotome over time, from its initial formation to the mature structure. The sclerotome is the portion of the somite that will give rise to a vertebra.
61057	peptidoglycan recognition protein signaling pathway	P	A series of molecular signals initiated by binding of peptidoglycan to a receptor on the surface of the target cell and ending with regulation of a downstream cellular process. The main outcome of the Imd signaling is the production of antimicrobial peptides.
61058	regulation of peptidoglycan recognition protein signaling pathway	P	Any process that modulates the rate, frequency, or extent of the peptidoglycan recognition protein signaling pathway.
61059	positive regulation of peptidoglycan recognition protein signaling pathway	P	Any process that increases the rate, frequency, or extent of the peptidoglycan recognition protein signaling pathway.
61060	negative regulation of peptidoglycan recognition protein signaling pathway	P	Any process that decreases the rate, frequency, or extent of the peptidoglycan recognition protein signaling pathway.
61061	muscle structure development	P	The progression of a muscle structure over time, from its formation to its mature state. Muscle structures are contractile cells, tissues or organs that are found in multicellular organisms.
61062	regulation of nematode larval development	P	Any process that modulates the rate, frequency, or extent of nematode larval development, the process whose specific outcome is the progression of the nematode larva over time, from its formation to the mature structure. Nematode larval development begins with the newly hatched first-stage larva (L1) and ends with the end of the last larval stage (for example the fourth larval stage (L4) in C. elegans). Each stage of nematode larval development is characterized by proliferation of specific cell lineages and an increase in body size without alteration of the basic body plan. Nematode larval stages are separated by molts in which each stage-specific exoskeleton, or cuticle, is shed and replaced anew.
61063	positive regulation of nematode larval development	P	Any process that increases the rate, frequency, or extent of nematode larval development, the process whose specific outcome is the progression of the nematode larva over time, from its formation to the mature structure. Nematode larval development begins with the newly hatched first-stage larva (L1) and ends with the end of the last larval stage (for example the fourth larval stage (L4) in C. elegans). Each stage of nematode larval development is characterized by proliferation of specific cell lineages and an increase in body size without alteration of the basic body plan. Nematode larval stages are separated by molts in which each stage-specific exoskeleton, or cuticle, is shed and replaced anew.
61064	negative regulation of nematode larval development	P	Any process that decreases the rate, frequency, or extent of nematode larval development, the process whose specific outcome is the progression of the nematode larva over time, from its formation to the mature structure. Nematode larval development begins with the newly hatched first-stage larva (L1) and ends with the end of the last larval stage (for example the fourth larval stage (L4) in C. elegans). Each stage of nematode larval development is characterized by proliferation of specific cell lineages and an increase in body size without alteration of the basic body plan. Nematode larval stages are separated by molts in which each stage-specific exoskeleton, or cuticle, is shed and replaced anew.
61065	regulation of dauer larval development	P	Any process that modulates the rate, frequency, or extent of dauer larval development, the process whose specific outcome is the progression of the dauer larva over time, through the facultative diapause of the dauer (enduring) larval stage, with specialized traits adapted for dispersal and long-term survival, with elevated stress resistance and without feeding.
61066	positive regulation of dauer larval development	P	Any process that increases the rate, frequency, or extent of dauer larval development, the process whose specific outcome is the progression of the dauer larva over time, through the facultative diapause of the dauer (enduring) larval stage, with specialized traits adapted for dispersal and long-term survival, with elevated stress resistance and without feeding.
61067	negative regulation of dauer larval development	P	Any process that decreases the rate, frequency, or extent of dauer larval development, the process whose specific outcome is the progression of the dauer larva over time, through the facultative diapause of the dauer (enduring) larval stage, with specialized traits adapted for dispersal and long-term survival, with elevated stress resistance and without feeding.
61068	urethra development	P	The progression of the urethra over time from its initial formation to the mature structure. The urethra is a renal system organ that carries urine from the bladder to outside the body.
61069	male urethra development	P	The progression of the male urethra over time from its initial formation to the mature structure. The male urethra is a renal system organ that carries urine from the bladder through the penis to outside the body.
61070	female urethra development	P	The progression of the female urethra over time from its initial formation to the mature structure. The female urethra is a renal system organ that carries urine from the bladder to outside the body, exiting above the vaginal opening.
61071	urethra epithelium development	P	The progression of the urethra epithelium over time from its initial formation to the mature structure. The urethra is a renal system organ that carries urine from the bladder to outside the body. The epithelium is the tubular, planar layer of cells through which the urine passes.
61072	iris morphogenesis	P	The process in which the iris is generated and organized. The iris is an anatomical structure in the eye whose opening forms the pupil. The iris is responsible for controlling the diameter and size of the pupil and the amount of light reaching the retina.
61073	ciliary body morphogenesis	P	The process in which the ciliary body generated and organized. The ciliary body is the circumferential tissue inside the eye composed of the ciliary muscle and ciliary processes.
61074	regulation of neural retina development	P	Any process that modulates the rate, frequency, or extent of neural retina development, the progression of the neural retina over time from its initial formation to the mature structure. The neural retina is the part of the retina that contains neurons and photoreceptor cells.
61075	positive regulation of neural retina development	P	Any process that increases the rate, frequency, or extent of neural retina development, the progression of the neural retina over time from its initial formation to the mature structure. The neural retina is the part of the retina that contains neurons and photoreceptor cells.
61076	negative regulation of neural retina development	P	Any process that decreases the rate, frequency, or extent of neural retina development, the progression of the neural retina over time from its initial formation to the mature structure. The neural retina is the part of the retina that contains neurons and photoreceptor cells.
61077	chaperone-mediated protein folding	P	The process of inhibiting aggregation and assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure that is dependent on interaction with a chaperone.
61078	positive regulation of prostaglandin secretion involved in immune response	P	Any process that activates or increases the frequency, rate or extent of the regulated release of a prostaglandin from a cell and contributes to the immune response.
61079	left horn of sinus venosus development	P	The progression of the left horn of the sinus venosus from its initial formation to the mature structure.
61080	right horn of sinus venosus development	P	The progression of the right horn of the sinus venosus from its formation to the mature structure.
61081	positive regulation of myeloid leukocyte cytokine production involved in immune response	P	Any process that modulates the rate, frequency, or extent of the production of a cytokine that contributes to the immune response.
61082	myeloid leukocyte cytokine production	P	Any process that contributes to cytokine production by a myeloid cell.
61083	regulation of protein refolding	P	Any process that regulates the rate, frequency, or extent of protein refolding. Protein refolding is the process carried out by a cell that restores the biological activity of an unfolded or misfolded protein, using helper proteins such as chaperones.
61084	negative regulation of protein refolding	P	Any process that decreases the rate, frequency, or extent of protein refolding. Protein refolding is the process carried out by a cell that restores the biological activity of an unfolded or misfolded protein, using helper proteins such as chaperones.
61085	regulation of histone H3-K27 methylation	P	Any process that modulates the rate, frequency, or extent of histone H3-K27 methylation. Histone H3-K27 methylation is the modification of histone H3 by addition of a methyl group to lysine at position 27 of the histone.
61086	negative regulation of histone H3-K27 methylation	P	Any process that decreases the rate, frequency, or extent of histone H3-K27 methylation. Histone H3-K27 methylation is the modification of histone H3 by addition of a methyl group to lysine at position 27 of the histone.
61087	positive regulation of histone H3-K27 methylation	P	Any process that increases the rate, frequency, or extent of histone H3-K27 methylation. Histone H3-K27 methylation is the modification of histone H3 by addition of a methyl group to lysine at position 27 of the histone.
61088	regulation of sequestering of zinc ion	P	Any process that modulates the rate, frequency, or extent of sequestering of zinc ion. Sequestering of zinc ion is the process of binding or confining zinc ions such that they are separated from other components of a biological system.
61089	negative regulation of sequestering of zinc ion	P	Any process that decreases the rate, frequency, or extent of sequestering of zinc ion. Sequestering of zinc ion is the process of binding or confining zinc ions such that they are separated from other components of a biological system.
61090	positive regulation of sequestering of zinc ion	P	Any process that increases the rate, frequency, or extent of sequestering of zinc ion. Sequestering of zinc ion is the process of binding or confining zinc ions such that they are separated from other components of a biological system.
61091	regulation of phospholipid translocation	P	Any process that modulates the frequency, rate or extent of the translocation, or flipping, of phospholipid molecules from one monolayer of a membrane bilayer to the opposite monolayer.
61092	positive regulation of phospholipid translocation	P	Any process that increases the frequency, rate or extent of the translocation, or flipping, of phospholipid molecules from one monolayer of a membrane bilayer to the opposite monolayer.
61093	negative regulation of phospholipid translocation	P	Any process that decreases the frequency, rate or extent of the translocation, or flipping, of phospholipid molecules from one monolayer of a membrane bilayer to the opposite monolayer.
61094	regulation of turning behavior involved in mating	P	Any process that modulates the rate, frequency or extent of turning behavior involved in mating. Turning behavior is the sharp ventral turn performed by the male as he approaches either the hermaphrodite head or tail, whilst trying to locate his partner's vulva. Turning occurs via a sharp ventral coil of the male's tail.
61095	positive regulation of turning behavior involved in mating	P	Any process that increases the rate, frequency or extent of turning behavior involved in mating. Turning behavior is the sharp ventral turn performed by the male as he approaches either the hermaphrodite head or tail, whilst trying to locate his partner's vulva. Turning occurs via a sharp ventral coil of the male's tail.
61096	negative regulation of turning behavior involved in mating	P	Any process that decreases the rate, frequency or extent of turning behavior involved in mating. Turning behavior is the sharp ventral turn performed by the male as he approaches either the hermaphrodite head or tail, whilst trying to locate his partner's vulva. Turning occurs via a sharp ventral coil of the male's tail.
61097	regulation of protein tyrosine kinase activity	P	Any process that modulates the rate, frequency, or extent of protein tyrosine kinase activity.
61098	positive regulation of protein tyrosine kinase activity	P	Any process that increases the rate, frequency, or extent of protein tyrosine kinase activity.
61099	negative regulation of protein tyrosine kinase activity	P	Any process that decreases the rate, frequency, or extent of protein tyrosine kinase activity.
61100	lung neuroendocrine cell differentiation	P	The process in which a relatively unspecialized cell acquires specialized features of a neuroendocrine cell of the lung epithelium.
61101	neuroendocrine cell differentiation	P	The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a neuroendocrine cell. A neuroendocrine cell is a cell that receives input form a neuron which controls the secretion of an endocrine substance.
61102	stomach neuroendocrine cell differentiation	P	The process in which a relatively unspecialized cell acquires specialized features of a neuroendocrine cell of the stomach epithelium.
61103	carotid body glomus cell differentiation	P	The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a glomus cell of the carotid body. The carotid body is a specialized chemosensory organ that helps respond to hypoxia.
61104	adrenal chromaffin cell differentiation	P	The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of an adrenal chromaffin cell. An adrenal chromaffin cell is a neuroendocrine cell that stores epinephrine secretory vesicles.
61105	regulation of stomach neuroendocrine cell differentiation	P	Any process that modulates the rate, frequency or extent of the differentiation of a neuroendocrine cell in the stomach.
61106	negative regulation of stomach neuroendocrine cell differentiation	P	Any process that decreases the rate, frequency or extent of the differentiation of a neuroendocrine cell in the stomach.
61107	seminal vesicle development	P	The progression of the seminal vesicle over time, from its formation to the mature structure. The seminal vesicle is a gland that contributes to the production of semen.
61108	seminal vesicle epithelium development	P	The progression of the seminal vesicle epithelium over time, from its formation to the mature structure.
61109	dense core granule organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a dense core granule. A dense core granule is a secretory organelle found in endocrine cells.
61110	dense core granule biogenesis	P	A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a dense core granule. Includes biosynthesis of constituent macromolecules, and those macromolecular modifications that are involved in synthesis or assembly of the dense core granule.
61111	epithelial-mesenchymal cell signaling involved in lung development	P	Any process that results in the transfer of information from an epithelial cell to a mesenchymal cell and contributes to the progression of the lung over time from its initial formation to the mature organ.
61112	negative regulation of bud outgrowth involved in lung branching	P	Any process that decreases the rate, frequency, or extent of bud outgrowth involved in lung branching.
61113	pancreas morphogenesis	P	Morphogenesis of the pancreas. Morphogenesis is the process in which anatomical structures are generated and organized.
61114	branching involved in pancreas morphogenesis	P	The process in which the branches of the pancreas are generated and organized.
61115	lung proximal/distal axis specification	P	The establishment, maintenance and elaboration of the proximal/distal axis of the lung. The proximal/distal axis of the lung is defined by a line that runs from the trachea to the alveoli.
61116	ductus venosus closure	P	The morphogenesis process in which the ductus venosus changes to no longer permit blood flow after birth.
61117	negative regulation of heart growth	P	Any process that decreases the rate or extent of heart growth. Heart growth is the increase in size or mass of the heart.
61118	regulation of positive chemotaxis to cAMP	P	Any process that modulates the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP.
61119	regulation of positive chemotaxis to cAMP by chlorinated alkylphenone	P	Any process that modulates the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of a chlorinated alkylphenone. An alkylphenone is an aromatic polyketide with methyl and chlorine substitutions.
61120	regulation of positive chemotaxis to cAMP by DIF-1	P	Any process that modulates the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of DIF-1. DIF-1 is a chlorinated alkylphenone.
61121	regulation of positive chemotaxis to cAMP by DIF-2	P	Any process that modulates the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of DIF-2. DIF-2 is a chlorinated alkylphenone.
61122	positive regulation of positive chemotaxis to cAMP	P	Any process that increases the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP.
61123	negative regulation of positive chemotaxis to cAMP	P	Any process that decreases the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP.
61124	positive regulation of positive chemotaxis to cAMP by chlorinated alkylphenone	P	Any process that increases the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of a chlorinated alkylphenone. An alkylphenone is an aromatic polyketide with methyl and chlorine substitutions.
61125	negative regulation of positive chemotaxis to cAMP by chlorinated alkylphenone	P	Any process that decreases the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of a chlorinated alkylphenone. An alkylphenone is an aromatic polyketide with methyl and chlorine substitutions.
61126	positive regulation of positive chemotaxis to cAMP by DIF-1	P	Any process that increases the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of DIF-1. DIF-1 is a chlorinated alkylphenone.
61127	negative regulation of positive chemotaxis to cAMP by DIF-1	P	Any process that decreases the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of DIF-1. DIF-1 is a chlorinated alkylphenone.
61128	positive regulation of chemotaxis to cAMP by DIF-2	P	Any process that increases the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of DIF-2. DIF-2 is a chlorinated alkylphenone.
61129	negative regulation of positive chemotaxis to cAMP by DIF-2	P	Any process that decreases the rate, frequency, or extent of directed movement of a motile cell or organism up a concentration gradient of 3',5'-cAMP by the action of DIF-2. DIF-2 is a chlorinated alkylphenone.
61130	pancreatic bud formation	P	The morphogenetic process in which the foregut region specified to become the pancreas forms a bud.
61131	pancreas field specification	P	The process in which a specific region of the gut is delineated into the area in which the pancreas will develop.
61132	pancreas induction	P	The close range interaction of two or more cells or tissues that causes the cells of the gut to change their fates and specify the development of the pancreas.
61133	endopeptidase activator activity	F	Increases the activity of an endopeptidase, any enzyme that hydrolyzes nonterminal peptide bonds in polypeptides.
61134	peptidase regulator activity	F	Modulates the activity of a peptidase, any enzyme that catalyzes the hydrolysis peptide bonds.
61135	endopeptidase regulator activity	F	Modulates the activity of a peptidase, any enzyme that hydrolyzes nonterminal peptide bonds in polypeptides.
61136	regulation of proteasomal protein catabolic process	P	Any process that modulates the rate, frequency, or extent of the chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds that is mediated by the proteasome.
61137	bud dilation	P	The process in which a branch bud increases radially. A branch bud is the initial area of outgrowth in the formation of a new branch.
61138	morphogenesis of a branching epithelium	P	The process in which the anatomical structures of a branched epithelium are generated and organized.
61139	bud field specification	P	The regionalization process in which the identity of a bud primordium is specified. Identity is considered to be the aggregate of characteristics by which a structure is recognized.
61140	lung secretory cell differentiation	P	The process in which a relatively unspecialized cell acquires specialized features of a lung secretory cell. A lung secretory cell is a specialized epithelial cell of the lung that contains large secretory granules in its apical part.
61141	lung ciliated cell differentiation	P	The process in which a relatively unspecialized cell acquires specialized features of a lung ciliated cell. A lung ciliated cell is a specialized lung epithelial cell that contains cilia for moving substances released from lung secretory cells.
61142	mesothelial-mesenchymal cell signaling involved in early lung development	P	Any process that mediates the transfer of information from a mesothelial cell to an epithelial cell and contributes to the development of the lung.
61143	alveolar primary septum development	P	The progression of a primary alveolar septum over time, from its formation to the mature structure. A primary alveolar septum is a specialized epithelium that surrounds the saccule as it forms.
61144	alveolar secondary septum development	P	The progression of a secondary alveolar septum over time, from its formation to the mature structure. A secondary alveolar septum is a specialized epithelium that subdivides the initial saccule.
61145	lung smooth muscle development	P	The process whose specific outcome is the progression of smooth muscle in the lung over time, from its formation to the mature structure.
61146	Peyer's patch morphogenesis	P	The process in which a Peyer's patch is generated and organized. Peyer's patches are typically found as nodules associated with gut epithelium with distinct internal structures including B- and T-zones for the activation of lymphocytes.
61147	endocardial endothelium development	P	The progression of the endocardial endothelium over time, from its initial formation to the mature structure. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers.
61148	extracellular matrix organization involved in endocardium development	P	A process which results in the assembly, arrangement of constituent parts, or disassembly of an extracellular matrix of the endocardium. The endocardium is an anatomical structure comprised of an endothelium and an extracellular matrix that forms the innermost layer of tissue of the heart, and lines the heart chambers.
61149	BMP signaling pathway involved in ureter morphogenesis	P	A series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, which contributes to the shaping of the ureter. The ureter is a tube that extends from the kidney to the bladder.
61150	renal system segmentation	P	The regionalization process that divides an the renal system into a series of segments along its proximal/distal axis.
61151	BMP signaling pathway involved in renal system segmentation	P	A series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, which contributes to the segmentation of the renal system.
61152	trachea submucosa development	P	The progression of the trachea submucosa over time from its formation to the mature structure. The trachea submucosa is made up of the glands and elastic tissue that lie under the mucosa in the trachea.
61153	trachea gland development	P	The progression of a trachea gland over time, from its formation to the mature structure. Trachea glands are found under the mucus of the trachea and secrete mucus, and agents that help protect the lung from injury and infection.
61154	endothelial tube morphogenesis	P	The process in which the anatomical structures of a tube are generated and organized from an endothelium. Endothelium refers to the layer of cells lining blood vessels, lymphatics, the heart, and serous cavities, and is derived from bone marrow or mesoderm. Corneal endothelium is a special case, derived from neural crest cells.
61155	pulmonary artery endothelial tube morphogenesis	P	The process in which the anatomical structures of a tube are generated and organized from the pulmonary artery endothelium. An pulmonary artery endothelium is an epithelium that lines the pulmonary artery.
61156	pulmonary artery morphogenesis	P	The process in which the anatomical structures of the pulmonary artery are generated and organized. The pulmonary artery is the artery that carries blood from the heart to the lungs.
61157	mRNA destabilization	P	Any process that decreases the stability of an mRNA molecule, making it more vulnerable to degradative processes. Messenger RNA is the intermediate molecule between DNA and protein. It includes UTR and coding sequences. It does not contain introns.
61158	3'-UTR-mediated mRNA destabilization	P	An mRNA destabilization process in which one or more RNA-binding proteins associate with the 3'-untranslated region (UTR) of an mRNA.
61159	establishment of bipolar cell polarity involved in cell morphogenesis	P	The specification and formation of bipolar intracellular organization or cell growth patterns that contribute to cell morphogenesis. Bipolar organization is the organization that is a mirror image along an axis from a plane.
61160	regulation of establishment of bipolar cell polarity regulating cell shape	P	Any process that modulates the rate, frequency or extent of the establishment of bipolar cell polarity that contributes to the shape of a cell.
61161	positive regulation of establishment of bipolar cell polarity regulating cell shape	P	Any process that increases the rate, frequency or extent of the establishment of bipolar cell polarity that regulates the shape of a cell.
61162	establishment of monopolar cell polarity	P	The specification and formation of monopolar intracellular organization or cell growth patterns. Monopolar cell organization is directional organization along an axis.
61163	endoplasmic reticulum polarization	P	The endoplasmic reticulum organization process that results in the structure of the endoplasmic reticulum being oriented in the cell.
61164	transitional endoplasmic reticulum polarization at cell division site	P	The endoplasmic reticulum polarization process that results in the structure being polarized at the site of future cell division.
61165	endoplasmic reticulum localization involved in endoplasmic reticulum polarization at cell division site	P	The process in which endoplasmic reticulum is transiently localized to the site where a cell will divide.
61166	establishment of endoplasmic reticulum localization involved in endoplasmic reticulum polarization at cell division site	P	The directed movement of the endoplasmic reticulum to the site where a cell will divide.
61167	maintenance of endoplasmic reticulum location involved in endoplasmic reticulum polarization at cell division site	P	The process in which the endoplasmic reticulum is maintained at the site of cell division and is prevented from moving elsewhere.
61168	regulation of hair follicle placode formation	P	Any process that modulates the rate, frequency, or extent of hair follicle placode formation, the developmental process in which a hair placode forms. An hair follicle placode is a thickening of the ectoderm that will give rise to the hair follicle bud.
61169	positive regulation of hair placode formation	P	Any process that increases the rate, frequency, or extent of hair follicle placode formation, the developmental process in which a hair placode forms. An hair follicle placode is a thickening of the ectoderm that will give rise to the hair follicle bud.
61170	negative regulation of hair follicle placode formation	P	Any process that decreases the rate, frequency, or extent of hair follicle placode formation, the developmental process in which a hair placode forms. An hair follicle placode is a thickening of the ectoderm that will give rise to the hair follicle bud.
61171	establishment of bipolar cell polarity	P	The specification and formation of bipolar intracellular organization or cell growth patterns. Bipolar organization is the organization that is a mirror image along an axis from a plane.
61172	regulation of establishment of bipolar cell polarity	P	Any process that modulates the rate, frequency or extent of the establishment of bipolar cell polarity. Bipolar organization is the organization that is a mirror image along an axis from a plane.
61173	positive regulation of establishment of bipolar cell polarity	P	Any process that increases the rate, frequency or extent of the establishment of bipolar cell polarity.
61174	type I terminal bouton	C	Terminal inflated portion of the axon of a glutamatergic neuron, containing the specialized apparatus necessary to release neurotransmitters that will induce the contraction of muscle. The axon terminus is considered to be the whole region of thickening and the terminal bouton is a specialized region of it.
61175	type II terminal bouton	C	Terminal inflated portion of the axon of a non-glutamatergic neuron, containing the specialized apparatus necessary to release neurotransmitters at a regulatory synapse. The axon terminus is considered to be the whole region of thickening and the terminal bouton is a specialized region of it.
61176	type Ib terminal bouton	C	Terminal inflated portion of the axon of a glutamatergic neuron, containing the specialized apparatus necessary for the tonic release neurotransmitters that will induce the contraction of muscle. Type Ib terminal boutons are larger than type Is terminal boutons.
61177	type Is terminal bouton	C	Terminal inflated portion of the axon of a glutamatergic neuron, containing the specialized apparatus necessary for the phasic release neurotransmitters that will induce the contraction of muscle. Type Is terminal boutons are smaller than type Ib terminal boutons.
61178	regulation of insulin secretion involved in cellular response to glucose stimulus	P	Any process that modulates the frequency, rate or extent of the regulated release of insulin that contributes to the response of a cell to glucose.
61179	negative regulation of insulin secretion involved in cellular response to glucose stimulus	P	Any process that decreases the frequency, rate or extent of the regulated release of insulin that contributes to the response of a cell to glucose.
61180	mammary gland epithelium development	P	The process whose specific outcome is the progression of the mammary gland epithelium over time, from its formation to the mature structure. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk.
61181	regulation of chondrocyte development	P	Any process that modulates the rate, frequency, or extent of the process whose specific outcome is the progression of a chondrocyte over time, from its commitment to its mature state. Chondrocyte development does not include the steps involved in committing a chondroblast to a chondrocyte fate.
61182	negative regulation of chondrocyte development	P	Any process that decreases the rate, frequency, or extent of the process whose specific outcome is the progression of a chondrocyte over time, from its commitment to its mature state. Chondrocyte development does not include the steps involved in committing a chondroblast to a chondrocyte fate.
61183	regulation of dermatome development	P	Any process that modulates the rate, frequency, or extent of the progression of the dermatome over time, from its initial formation to the mature structure. The dermatome is the portion of a somite that will form skin.
61184	positive regulation of dermatome development	P	Any process that increases the rate, frequency, or extent of the progression of the dermatome over time, from its initial formation to the mature structure. The dermatome is the portion of a somite that will form skin.
61185	negative regulation of dermatome development	P	Any process that decreases the rate, frequency, or extent of the progression of the dermatome over time, from its initial formation to the mature structure. The dermatome is the portion of a somite that will form skin.
61186	negative regulation of chromatin silencing at silent mating-type cassette	P	Any process that decreases the frequency, rate, or extent of chromatin silencing at silent mating-type cassette. Chromatin silencing at silent mating-type cassette is the repression of transcription at silent mating-type loci by altering the structure of chromatin.
61187	regulation of chromatin silencing at rDNA	P	Any process that modulates the rate, frequency, or extent of the repression of transcription of ribosomal DNA by altering the structure of chromatin.
61188	negative regulation of chromatin silencing at rDNA	P	Any process that decreases the rate, frequency, or extent of the repression of transcription of ribosomal DNA by altering the structure of chromatin.
61189	positive regulation of sclerotome development	P	Any process that increases the rate, frequency, or extent of the progression of the sclerotome over time, from its initial formation to the mature structure. The sclerotome is the portion of the somite that will give rise to a vertebra.
61190	regulation of sclerotome development	P	Any process that modulates the rate, frequency, or extent of the progression of the sclerotome over time, from its initial formation to the mature structure. The sclerotome is the portion of the somite that will give rise to a vertebra.
61191	positive regulation of vacuole fusion, non-autophagic	P	Any process that increases the frequency, rate or extent of the fusion of two vacuole membranes to form a single vacuole.
61192	negative regulation of vacuole fusion, non-autophagic	P	Any process that decreases the frequency, rate or extent of the fusion of two vacuole membranes to form a single vacuole.
61193	taste bud development	P	The progression of the taste bud over time, from its formation to the mature state. The taste bud is a specialized area of the tongue that contains taste receptors.
61194	taste bud morphogenesis	P	The process in which the anatomical structures of the taste bud are generated and organized. The taste bud is a specialized area of the tongue that contains taste receptors.
61195	taste bud formation	P	The developmental process pertaining to the initial formation of the taste bud from unspecified parts. The taste bud is a specialized area of the tongue that contains taste receptors.
61196	fungiform papilla development	P	The progression of the fungiform papilla over time, from its formation to the mature structure. The fungiform papilla is a mushroom-shaped papilla of the tongue.
61197	fungiform papilla morphogenesis	P	The process in which the anatomical structures of the fungiform papilla are generated and organized. The fungiform papilla is a mushroom-shaped papilla of the tongue.
61198	fungiform papilla formation	P	The developmental process pertaining to the initial formation of a spongiform papilla from unspecified parts. The fungiform papilla is a mushroom-shaped papilla of the tongue.
61199	striated muscle contraction involved in embryonic body morphogenesis	P	The process in which force is generated within striated embryonic muscle tissue, resulting in a contraction of the muscle that contributes to the formation of an embryo's characteristic body morphology.
61200	clathrin-sculpted gamma-aminobutyric acid transport vesicle	C	A clathrin-sculpted lipid bilayer membrane-enclosed vesicle after clathrin release and containing gamma-aminobutyric acid transport vesicle.
61201	clathrin-sculpted gamma-aminobutyric acid transport vesicle lumen	C	The volume enclosed by the membrane of the clathrin-sculpted gamma-aminobutyric acid transport vesicle.
61202	clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane	C	The lipid bilayer surrounding a clathrin-sculpted gamma-aminobutyric acid transport vesicle.
61203	striated muscle paramyosin thick filament assembly	P	The aggregation, arrangement and bonding together of proteins to form the paramyosin-based thick filaments of myofibrils in striated muscle.
61204	paramyosin filament assembly or disassembly	P	The formation or disassembly of a filament composed of paramyosin molecules.
61205	paramesonephric duct development	P	The process whose specific outcome is the progression of the paramesonephric duct over time, from its formation to the mature structure. Mullerian ducts (or paramesonephric ducts) are paired ducts of the embryo that run down the lateral sides of the urogenital ridge and terminate at the mullerian eminence in the primitive urogenital sinus. In the female, they will develop to form the fallopian tubes, uterus, cervix, and the upper portion of the vagina; in the male, they are lost. These ducts are made of tissue of mesodermal origin.
61206	mesonephros morphogenesis	P	The process in which the anatomical structures of the mesonephros are generated and organized.
61207	mesonephric juxtaglomerulus cell differentiation	P	The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the juxtaglomerulus cells of the mesonephros as it progresses from its formation to the mature state.
61208	cell differentiation involved in mesonephros development	P	The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the mesonephros as it progresses from its formation to the mature state.
61209	cell proliferation involved in mesonephros development	P	The multiplication or reproduction of cells, resulting in the expansion of the population in the mesonephros.
61210	cell-cell signaling involved in mesonephros development	P	Any process that mediates the transfer of information from one cell to another and contributes to the progression of the mesonephros over time, from its formation to the mature organ.
61211	mesonephric collecting duct development	P	The process whose specific outcome is the progression of a collecting duct in the mesonephros over time, from its formation to the mature structure. The collecting duct regulates water, electrolyte and acid-base balance. The collecting duct is the final common path through which urine flows before entering the ureter and then emptying into the bladder.
61212	mesonephric juxtaglomerular apparatus development	P	The process whose specific outcome is the progression of the juxtaglomerular apparatus in the mesonephros over time, from its formation to the mature structure. The juxtaglomerular apparatus is an anatomical structure which consists of juxtaglomerular cells, extraglomerular mesangial cells and the macula densa. The juxtaglomerular apparatus lies adjacent to the glomerulus and regulates kidney function by maintaining the blood flow to the kidney and the filtration rate.
61213	positive regulation of mesonephros development	P	Any process that increases the rate, frequency or extent of mesonephros development. Mesonephros development is the process whose specific outcome is the progression of the mesonephros over time, from its formation to the mature structure. The mesonephros is an organ that filters the blood and excretes the end products of body metabolism in the form of urine.
61214	mesonephric smooth muscle tissue development	P	The process whose specific outcome is the progression of smooth muscle in the mesonephros over time, from its formation to the mature structure.
61215	mesonephric nephron development	P	The process whose specific outcome is the progression of a nephron in the mesonephros over time, from its formation to the mature structure. A nephron is the functional unit of the kidney.
61216	regulation of transcription from RNA polymerase II promoter involved in mesonephros development	P	Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that contributes to the mesonephros progressing from its initial formation to the mature state.
61217	regulation of mesonephros development	P	Any process that modulates the rate, frequency or extent of mesonephros development. Mesonephros development is the process whose specific outcome is the progression of the mesonephros over time, from its formation to the mature structure. The mesonephros is an endocrine and metabolic organ that filters the blood and excretes the end products of body metabolism in the form of urine.
61218	negative regulation of mesonephros development	P	Any process that decreases the rate, frequency or extent of mesonephros development. Mesonephros development is the process whose specific outcome is the progression of the mesonephros over time, from its formation to the mature structure. The mesonephros is an organ that filters the blood and excretes the end products of body metabolism in the form of urine.
61219	mesonephric mesenchyme development	P	The biological process whose specific outcome is the progression of a mesonephric mesenchyme from an initial condition to its mature state. This process begins with the formation of mesonephric mesenchyme and ends with the mature structure. Mesonephric mesenchyme is the tissue made up of loosely connected mesenchymal cells in the mesonephros.
61220	mesonephric macula densa development	P	The process whose specific outcome is the progression of the mesonephric macula densa over time, from its formation to the mature structure. The mesonephric macula densa is an area of specialized cells in the distal tubule of the mesonephros that makes contact with the vascular pole of the glomerulus.
61221	mesonephric mesenchyme morphogenesis	P	The process in which the anatomical structures of a mesonephric mesenchymal tissue are generated and organized. Mesonephric mesenchyme is the tissue made up of loosely connected mesenchymal cells in the mesonephros.
61222	mesonephric mesenchymal cell proliferation involved in mesonephros development	P	The multiplication or reproduction of cells, resulting in the expansion of a mesonephric mesenchymal cell population.
61223	mesonephric mesenchymal cell differentiation	P	The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesenchymal cells of the mesonephros as it progresses from its formation to the mature state.
61224	mesonephric glomerulus development	P	The progression of the mesonephric glomerulus over time from its initial formation until its mature state. The mesonephric glomerulus is a capillary tuft which forms a close network with the visceral epithelium (podocytes) and the mesangium to form the filtration barrier and is surrounded by Bowman's capsule in nephrons of the mature vertebrate kidney, or mesonephros.
61225	mesonephric extraglomerular mesangial cell proliferation involved in mesonephros development	P	The multiplication or reproduction of extraglomerular glomerular mesangium cells in the mesonephros by cell division, resulting in the expansion of their population. Extraglomerular mesangial cells (also known as lacis cells, Goormaghtigh cells) are light-staining cells in the kidney found outside the glomerulus, near the vascular pole and macula densa.
61226	proximal/distal pattern formation involved in mesonephric nephron development	P	The regionalization process in which specific areas of cell differentiation are determined along a proximal/distal axis of a nephron in the mesonephros. The proximal/distal axis is defined by a line that runs from the glomerulus (proximal end) outward toward the mesonephric duct (distal end).
61227	pattern specification involved in mesonephros development	P	Any developmental process that results in the creation of defined areas or spaces within the mesonephros to which cells respond and eventually are instructed to differentiate.
61228	mesonephric nephron morphogenesis	P	The process in which the anatomical structures of the mesonephric nephron are generated and organized. A mesonephric nephron is the functional unit of the mesonephros.
61229	mesonephric juxtaglomerulus cell development	P	The process whose specific outcome is the progression of a mesonephric juxtaglomerulus cell over time, from its formation to the mature structure.
61230	mesonephric juxtaglomerulus cell fate commitment	P	The process in which the developmental fate of a cell becomes restricted such that it will develop into a mesonephric juxtaglomerulus cell.
61231	mesonephric glomerulus vasculature development	P	The biological process whose specific outcome is the progression of a mesonephric glomerulus vasculature from an initial condition to its mature state. This process begins with the formation of the mesonephric glomerulus vasculature and ends with the mature structure. The mesonephric glomerulus vasculature is composed of the tubule structures that carry blood or lymph in the mesonephric glomerulus.
61232	mesonephric glomerular epithelium development	P	The process whose specific outcome is the progression of the mesonephric glomerular epithelium over time, from its formation to the mature structure. The mesonephric glomerular epithelium is an epithelial tissue that covers the outer surfaces of the glomerulus in the mesonephros. The mesonephric glomerular epithelium consists of both parietal and visceral epithelium. Mesonephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport. A mesonephric glomerular visceral epithelial cell is a specialized epithelial cell that contains "feet" that interdigitate with the "feet" of other glomerular epithelial cells in the mesonephros.
61233	mesonephric glomerular basement membrane development	P	The process whose specific outcome is the progression of the mesonephric glomerular basement membrane over time, from its formation to the mature structure. The mesonephric glomerular basement membrane is the basal laminal portion of the mesonephric glomerulus which performs the actual filtration.
61234	mesonephric glomerulus morphogenesis	P	The process in which the anatomical structures of the mesonephric glomerulus are generated and organized. The mesonephric glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate mesonephros.
61235	mesenchymal stem cell maintenance involved in mesonephric nephron morphogenesis	P	The process in which an organism retains a population of mesenchymal stem cells that contributes to the shaping of a nephron in the mesonephros. A mesenchymal stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells.
61236	mesonephric comma-shaped body morphogenesis	P	The process in which the mesonephric comma-shaped body is generated and organized. The mesonephric comma-shaped body is the precursor structure to the mesonephric S-shaped body that contributes to the morphogenesis of a nephron in the mesonephros.
61237	convergent extension involved in mesonephric nephron morphogenesis	P	The morphogenetic process in which the renal epithelium narrows along one axis and lengthens in a perpendicular axis that contributes to the shaping of a nephron in the mesonephros.
61238	establishment of planar polarity involved in mesonephric nephron morphogenesis	P	Coordinated organization of groups of cells in the plane of an epithelium that contributes to the shaping of a nephron in the mesonephros.
61239	mesenchymal stem cell differentiation involved in mesonephric nephron morphogenesis	P	The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal stem cell that contributes to the shaping of a nephronin the mesonephros. A mesenchymal stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells.
61240	mesonephric nephron tubule morphogenesis	P	The process in which the anatomical structures of a mesonephric nephron tubule are generated and organized. A mesonephric nephron tubule is an epithelial tube that is part of the mesonephric nephron, the functional part of the mesonephros.
61241	mesonephric nephron epithelium development	P	The process whose specific outcome is the progression of the mesonephric nephron epithelium over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. The mesonephric nephron epithelium is a tissue that covers the surface of a nephron in the mesonephros.
61242	mesonephric nephron tubule development	P	The progression of a mesonephric nephron tubule over time, from its initial formation to the mature structure. A mesonephric nephron tubule is an epithelial tube that is part of the mesonephric nephron, the functional part of the mesonephros.
61243	mesonephric renal vesicle morphogenesis	P	The process in which the anatomical structures of the mesonephric renal vesicle are generated and organized. The renal vesicle is the primordial structure of the mesonephric nephron epithelium, and is formed by the condensation of mesenchymal cells.
61244	mesonephric S-shaped body morphogenesis	P	The process in which the mesonephric S-shaped body is generated and organized. The mesonephric S-shaped body is the successor of the mesonephric comma-shaped body that contributes to the morphogenesis of a nephron in the mesonephros.
61245	establishment or maintenance of bipolar cell polarity	P	Any cellular process that results in the specification, formation or maintenance of a bipolar intracellular organization or cell growth patterns.
61246	establishment or maintenance of bipolar cell polarity regulating cell shape	P	Any cellular process that results in the specification, formation or maintenance of a bipolar intracellular organization or cell growth patterns that regulates the shaping of a cell.
61247	mesonephric glomerular mesangium development	P	The process whose specific outcome is the progression of the mesonephric glomerular mesangium over time, from its formation to the mature structure. The mesonephric glomerular mesangium is the thin membrane connective tissue composed of mesangial cells in the mesonephros, which helps to support the capillary loops in a renal glomerulus.
61248	mesonephric glomerulus vasculature morphogenesis	P	The process in which the anatomical structures of the mesonephric glomerulus vasculature are generated and organized. The mesonephric glomerulus vasculature is composed of the tubule structures that carry blood or lymph in the mesonephric glomerulus.
61249	mesonephric glomerular capillary formation	P	The process that gives rise to a mesonephric glomerular capillary. This process pertains to the initial formation of a structure from unspecified parts.
61250	mesonephric glomerular epithelial cell differentiation	P	The process in which a relatively unspecialized cell acquires specialized features of a mesonephric glomerular epithelial cell. Mesonephric glomerular epithelial cells are specialized epithelial cells that form part of the mesonephric glomerulus; there are two types, mesonephric glomerular parietal epithelial cells and mesonephric glomerular visceral epithelial cells.
61251	mesonephric glomerular epithelial cell development	P	The process whose specific outcome is the progression of a mesonephric glomerular epithelial cell over time, from its formation to the mature structure. Mesonephric glomerular epithelial cells are specialized epithelial cells that form part of the mesonephric glomerulus; there are two types, mesonephric glomerular parietal epithelial cells and mesonephric glomerular visceral epithelial cells.
61252	mesonephric glomerular epithelial cell fate commitment	P	The process in which the developmental fate of a cell becomes restricted such that it will develop into a mesonephric glomerular epithelial cell. Mesonephric glomerular epithelial cells are specialized epithelial cells that form part of the mesonephric glomerulus; there are two types, mesonephric glomerular parietal epithelial cells and mesonephric glomerular visceral epithelial cells.
61253	mesonephric glomerular parietal epithelial cell differentiation	P	The process in which a relatively unspecialized cell acquires specialized features of a mesonephric glomerular parietal epithelial cell. Mesonephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport.
61254	mesonephric glomerular parietal epithelial cell development	P	The process whose specific outcome is the progression of a mesonephric glomerular parietal epithelial cell over time, from its formation to the mature structure. Mesonephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport.
61255	mesonephric glomerular parietal epithelial cell fate commitment	P	The process in which the developmental fate of a cell becomes restricted such that it will develop into a mesonephric glomerular parietal epithelial cell. Mesonephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport. These cells may also give rise to podocytes.
61256	mesonephric glomerular visceral epithelial cell differentiation	P	The process in which a relatively unspecialized cell acquires specialized features of a mesonephric glomerular visceral epithelial cell. A mesonephric glomerular visceral epithelial cell is a specialized epithelial cell that contains "feet" that interdigitate with the "feet" of other glomerular epithelial cells in the mesonephros.
61257	mesonephric glomerular visceral epithelial cell development	P	The process whose specific outcome is the progression of a mesonephric glomerular visceral epithelial cell over time, from its formation to the mature structure. A mesonephric glomerular visceral epithelial cell is a specialized epithelial cell that contains "feet" that interdigitate with the "feet" of other glomerular epithelial cells in the mesonephros.
61258	mesonephric glomerular visceral epithelial cell fate commitment	P	The process in which the developmental fate of a cell becomes restricted such that it will develop into a mesonephric glomerular visceral epithelial cell. A mesonephric glomerular visceral epithelial cell is a specialized epithelial cell that contains "feet" that interdigitate with the "feet" of other glomerular epithelial cells in the mesonephros.
61259	mesonephric glomerular mesangial cell differentiation	P	The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the glomerular mesangial cells of the mesonephros as it progresses from its formation to the mature state.
61260	mesonephric mesangial cell differentiation	P	The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesangial cells of the mesonephros as it progresses from its formation to the mature state.
61261	mesenchymal to epithelial transition involved in mesonephros morphogenesis	P	A transition where a mesenchymal cell establishes apical/basolateral polarity, forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the mesonephros.
61262	mesonephric renal vesicle formation	P	The developmental process pertaining to the initial formation of the mesonephros.
61263	mesonephric glomerular mesangial cell development	P	The process whose specific outcome is the progression of a glomerular mesangial cell in the mesonephros over time, from its formation to the mature structure.
61264	mesonephric glomerular mesangial cell fate commitment	P	The process in which the developmental fate of a cell becomes restricted such that it will develop into a mesonephric glomerular mesangial cell.
61265	mesonephric nephron tubule epithelial cell differentiation	P	The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the mesonephric nephron tubule as it progresses from its formation to the mature state.
61266	mesonephric interstitial fibroblast differentiation	P	The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the interstitial fibroblasts of the mesonephros as it progresses from its formation to the mature state.
61267	mesonephric interstitial fibroblast development	P	The process whose specific outcome is the progression of a mesonephric interstitial fibroblast over time, from its formation to the mature structure.
61268	mesonephric interstitial fibroblast fate commitment	P	The process in which the developmental fate of a cell becomes restricted such that it will develop into a mesonephric interstitial fibroblast.
61269	mesonephric glomerular mesangial cell proliferation involved in mesonephros development	P	The multiplication or reproduction of glomerular mesangial cells in the mesonephros, resulting in the expansion of the population.
61270	mesonephric intraglomerular mesangial cell proliferation	P	The multiplication or reproduction of intraglomerular glomerular mesangium cells in the mesonephros by cell division, resulting in the expansion of their population. Intraglomerular mesangial cells are specialized pericytes located among the glomerular capillaries within a renal corpuscle of a kidney. They are required for filtration, structural support and phagocytosis.
61271	mesenchymal to epithelial transition involved in mesonephric renal vesicle formation	P	A transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the mesonephric renal vesicle.
61272	mesonephric connecting tubule development	P	The process whose specific outcome is the progression of the mesonephric connecting tubule over time, from its formation to the mature structure. The mesonephric connecting tubule is a tubular segment of the mesonephric nephron; it connects the distal tubule to the collecting duct in the mesonephros.
61273	mesonephric distal tubule morphogenesis	P	The process in which the anatomical structures of a mesonephric distal tubule are generated and organized. The mesonephric distal tubule is a mesonephric nephron tubule that begins at the macula densa and extends to the mesonephric connecting tubule.
61274	mesonephric distal tubule development	P	The process whose specific outcome is the progression of the mesonephric distal tubule over time, from its formation to the mature structure. The mesonephric distal tubule is a mesonephric nephron tubule that begins at the terminal segment of the proximal tubule and ends at the mesonephric connecting tubule.
61275	mesonephric proximal tubule development	P	The progression of the mesonephric proximal tubule over time, from its formation to the mature structure. The mesonephric proximal tubule extends from the capsule to the distal tubule.
61276	mesonephric proximal tubule morphogenesis	P	The process in which the anatomical structures of a mesonephric proximal tubule are generated and organized. The mesonephric proximal tubule extends from the capsule to the distal tubule.
61277	mesonephric nephron tubule formation	P	The developmental process pertaining to the initial formation of a mesonephric nephron tubule from unspecified parts. A mesonephric nephron tubule is an epithelial tube that is part of a nephron in the mesonephros.
61278	epithelial cell migration involved in mesonephric nephron tubule morphogenesis	P	The orderly movement of epithelial cells within a renal tubule that contributes to mesonephric nephron tubule morphogenesis.
61279	epithelial cell migration involved in mesonephric distal tubule morphogenesis	P	The orderly movement of epithelial cells within a renal tubule that contributes to mesonephric distal tubule morphogenesis.
61280	epithelial cell migration involved in mesonephric proximal tubule morphogenesis	P	The orderly movement of epithelial cells within a renal tubule that contributes to mesonephric proximal tubule morphogenesis.
61281	specification of mesonephric connecting tubule identity	P	The process in which the connecting tubule of the mesonephric nephron acquires its identity.
61282	specification of mesonephric nephron tubule identity	P	The process in which the tubules arranged along the proximal/distal axis of the mesonephric nephron acquire their identity.
61283	specification of mesonephric distal tubule identity	P	The process in which the distal tubule of the mesonephric nephron acquires its identity.
61284	specification of mesonephric proximal tubule identity	P	The process in which the proximal tubule of the mesonephric nephron acquires its identity.
61285	mesonephric capsule development	P	The progression of the mesonephric capsule over time, from its formation to the mature structure. The mesonephric capsule is the tough fibrous layer surrounding the mesonephros, covered in a thick layer of perinephric adipose tissue.
61286	mesonephric capsule morphogenesis	P	The process in which the anatomical structures of the mesonephric capsule are generated and organized. The mesonephric capsule is the tough fibrous layer surrounding the mesonephros, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage.
61287	mesonephric capsule formation	P	The developmental process pertaining to the initial formation of a mesonephric capsule from unspecified parts. The mesonephric capsule is the tough fibrous layer surrounding the mesonephros, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage.
61288	mesonephric capsule specification	P	The regionalization process in which the identity of the mesonephric capsule is specified. Identity is considered to be the aggregate of characteristics by which a structure is recognized.
61289	Wnt signaling pathway involved in kidney development	P	The series of molecular signals initiated by binding of Wnt protein to a receptor on the surface of the target cell, resulting a change in cell state that contributes to the progression of the kidney over time.
61290	canonical Wnt signaling pathway involved in metanephric kidney development	P	The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes that contribute to the progression of the metanephric kidney over time. In this pathway, the activated receptor signals via downstream effectors that result in the inhibition of beta-catenin phosphorylation, thereby preventing degradation of beta-catenin. Stabilized beta-catenin can then accumulate and travel to the nucleus to trigger changes in transcription of target genes.
61291	canonical Wnt signaling pathway involved in ureteric bud branching	P	The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes that contributes to the branching of the ureteric bud. In this pathway, the activated receptor signals via downstream effectors that result in the inhibition of beta-catenin phosphorylation, thereby preventing degradation of beta-catenin. Stabilized beta-catenin can then accumulate and travel to the nucleus to trigger changes in transcription of target genes.
61292	canonical Wnt signaling pathway involved in mesonephros development	P	The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes that contributes to the progression of the mesonephros over time. In this pathway, the activated receptor signals via downstream effectors that result in the inhibition of beta-catenin phosphorylation, thereby preventing degradation of beta-catenin. Stabilized beta-catenin can then accumulate and travel to the nucleus to trigger changes in transcription of target genes.
61293	canonical Wnt signaling pathway involved in mesonephric nephron development	P	The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes that contribute to the progression of the mesonephric nephron over time. In this pathway, the activated receptor signals via downstream effectors that result in the inhibition of beta-catenin phosphorylation, thereby preventing degradation of beta-catenin. Stabilized beta-catenin can then accumulate and travel to the nucleus to trigger changes in transcription of target genes.
61294	mesonephric renal vesicle induction	P	Signaling at short range between cells of the ureteric bud terminus and the kidney mesenchyme that positively regulates the formation of the mesonephric renal vesicle.
61295	regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis	P	Any process that modulates the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron in the mesonephros.
61296	negative regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis	P	Any process that reduces the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron in the mesonephros.
61297	positive regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis	P	Any process that increases the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron in the mesonephros.
61298	retina vasculature development in camera-type eye	P	The process whose specific outcome is the progression of the vasculature of the retina over time, from its formation to the mature structure.
61299	retina vasculature morphogenesis in camera-type eye	P	The process in which the vasculature of the retina is generated and organized.
61300	cerebellum vasculature development	P	The process whose specific outcome is the progression of the vasculature of the cerebellum over time, from its formation to the mature structure.
61301	cerebellum vasculature morphogenesis	P	The process in which the vasculature of the cerebellum is generated and organized.
61302	smooth muscle cell-matrix adhesion	P	The binding of a smooth muscle cell to the extracellular matrix via adhesion molecules.
61303	cornea development in camera-type eye	P	The progression of the cornea over time, from its formation to the mature structure. The cornea is the transparent structure that covers the anterior of the eye.
61304	retinal blood vessel morphogenesis	P	The process whose specific outcome is the progression of a blood vessel of the retina over time, from its formation to the mature structure.
61305	maintenance of bipolar cell polarity regulating cell shape	P	The maintenance of established bipolar anisotropic intracellular organization or cell growth patterns that results in the shaping of a cell.
61306	DNA strand renaturation involved in double-strand break repair	P	The identification and annealing of complementary base pairs in single-strand DNA that contributes to double-strand break repair.
61307	cardiac neural crest cell differentiation involved in heart development	P	The process in which a relatively unspecialized cell acquires specialized features of a cardiac neural crest cell that will migrate to the heart and contribute to its development. Cardiac neural crest cells are specialized cells that migrate toward the heart from the third, fourth and sixth pharyngeal arches.
61308	cardiac neural crest cell development involved in heart development	P	The process aimed at the progression of a cardiac neural crest cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell that contributes to the development of the heart.
61309	cardiac neural crest cell development involved in outflow tract morphogenesis	P	The process aimed at the progression of a cardiac neural crest cell over time, from initial commitment of the cell to its specific fate, to the fully functional differentiated cell that contributes to the shaping of the outflow tract.
61310	canonical Wnt signaling pathway involved in cardiac neural crest cell differentiation involved in heart development	P	The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes involved in cardiac neural crest cell differentiation.
61311	cell surface receptor signaling pathway involved in heart development	P	Any series of molecular signals initiated by the binding of a receptor on the surface of a cell to a physiological ligand, which contributes to the progression of the heart over time.
61312	BMP signaling pathway involved in heart development	P	A series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, which contributes to the progression of the heart over time.
61313	fibroblast growth factor receptor signaling pathway involved in heart development	P	The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands and contributing to the progression of the heart over time.
61314	Notch signaling involved in heart development	P	The series of molecular signals initiated by binding of an extracellular ligand to a Notch receptor on the surface of the target cell and contributing to the progression of the heart over time.
61315	canonical Wnt signaling pathway involved in positive regulation of cardiac muscle cell proliferation	P	The canonical Wnt signaling pathway that contributes to an expansion of the population of cardiac muscle cells.
61316	canonical Wnt signaling pathway involved in heart development	P	The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes that contributes to the progression of the heart over time. In this pathway, the activated receptor signals via downstream effectors that result in the inhibition of beta-catenin phosphorylation, thereby preventing degradation of beta-catenin. Stabilized beta-catenin can then accumulate and travel to the nucleus to trigger changes in transcription of target genes.
61317	canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment	P	The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes. In this pathway, the activated receptor signals via downstream effectors that result in the inhibition of beta-catenin phosphorylation, thereby preventing degradation of beta-catenin and contributing to cardiac muscle cell fate commitment. Stabilized beta-catenin can then accumulate and travel to the nucleus to trigger changes in transcription of target genes.
61318	renal filtration cell differentiation	P	The process in which a relatively unspecialized cell acquires specialized structural and/or functional features of a renal filtration cell. Renal filtration cells are specialized cells of the renal system that filter fluids by charge, size or both. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state.
61319	nephrocyte differentiation	P	The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a nephrocyte. A nephrocyte is an insect renal cell that filters hemolymph. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state.
61320	pericardial nephrocyte differentiation	P	The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a pericardial nephrocyte. A pericardial nephrocyte is an insect renal cell that filters hemolymph and is found with other pericardial nephrocytes in two rows flanking the dorsal vessel. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state.
61321	garland nephrocyte differentiation	P	The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a garland nephrocyte. A garland nephrocyte is an insect renal cell that filters hemolymph and forms a ring with other garland nephrocytes around the esophagus. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state.
61322	disseminated nephrocyte differentiation	P	The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a disseminated nephrocyte. A disseminated nephrocyte is an insect renal cell that filters hemolymph and is found at scattered locations in the fat body or other tissues. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state.
61323	cell proliferation involved in heart morphogenesis	P	The multiplication or reproduction of cells, resulting in the expansion of a cell population that contributes to the shaping of the heart.
61324	canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation	P	The canonical Wnt signaling pathway that contributes to the modulation of the expansion of a population of cardiac outflow tract cells.
61325	cell proliferation involved in outflow tract morphogenesis	P	The multiplication or reproduction of cells, resulting in the expansion of a cell population that contributes to the shaping of the outflow tract.
61326	renal tubule development	P	The progression of the renal tubule over time from its formation to the mature form. A renal tubule is a tube that filters, re-absorbs and secretes substances to rid an organism of waste and to play a role in fluid homeostasis.
61327	anterior Malpighian tubule development	P	The process whose specific outcome is the progression of the anterior Malpighian tubule over time, from its formation to the mature structure. The pair of anterior tubules arise from a dorsal region of the embryonic hindgut and projects forwards through the body cavity. A Malpighian tubule is a fine, thin-walled excretory tubule in insects which connects with the posterior part of the gut.
61328	posterior Malpighian tubule development	P	The process whose specific outcome is the progression of the posterior Malpighian tubule over time, from its formation to the mature structure. The pair of posterior tubules arise from a ventrolateral region of the embryonic hindgut and project backwards through the body cavity. A Malpighian tubule is a fine, thin-walled excretory tubule in insects which connects with the posterior part of the gut.
61329	Malpighian tubule principal cell differentiation	P	The process in which a relatively unspecialized cell acquires specialized features of a Malpighian tubule principal cell. A Malpighian tubule principal cell is an epithelial secretory cell that transports cations into the lumen of the tubule.
61330	Malpighian tubule stellate cell differentiation	P	The process in which a relatively unspecialized cell acquires specialized features of a Malpighian tubule stellate cell. A Malpighian tubule stellate cell is a specialized epithelial secretory cell that moves chloride ions and water across the tubule epithelium.
61331	epithelial cell proliferation involved in Malpighian tubule morphogenesis	P	The multiplication or reproduction of epithelial cells, resulting in the expansion of a cell population and contributing to the shaping of a Malpighian tubule.
61332	Malpighian tubule bud morphogenesis	P	The morphogenetic process in which a bud forms from the embryonic hindgut tube to form the Malpighian tubule. A bud is a protrusion that forms from the tube by localized changes in cell shape and position.
61333	renal tubule morphogenesis	P	The process in which the renal tubule is generated by specification of cell fate, through the maintenance of cell polarity, regulated cell proliferation and morphogenetic cell rearrangements, shape changes and growth. A renal tubule is a tube that filters, re-absorbs and secretes substances to rid an organism of waste and to play a role in fluid homeostasis.
61334	cell rearrangement involved in Malpighian tubule morphogenesis	P	The movement of an epithelial cell with respect to other epithelial cells that contributes to the shaping of the Malpighian tubule.
61335	cell growth involved in Malpighian tubule morphogenesis	P	The growth of an epithelial cell dependent on cycles of endoreplication, where growth contributes to the shaping of the Malpighian tubule.
61336	cell morphogenesis involved in Malpighian tubule morphogenesis	P	The shape change of an epithelial cell from a columnar to squamous cell morphology that contributes to the shaping of the Malpighian tubule.
61337	cardiac conduction	P	Transfer of an organized electrical impulse across the heart to coordinate the contraction of cardiac muscles. The process begins with generation of an action potential (in the sinoatrial node (SA) in humans) and ends with a change in the rate, frequency, or extent of the contraction of the heart muscles.
61339	establishment or maintenance of monopolar cell polarity	P	Any cellular process that results in the specification, formation or maintenance of monopolar intracellular organization or cell growth patterns. Monopolar cell organization is directional organization along an axis.
61340	establishment or maintenance of monopolar cell polarity regulating cell shape	P	Any cellular process that results in the specification, formation or maintenance of a monopolar intracellular organization or cell growth patterns that regulate the shape of a cell.
61341	non-canonical Wnt signaling pathway involved in heart development	P	The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via effectors other than beta-catenin and contributing to the progression of the heart over time.
61342	regulation of cell adhesion involved in heart morphogenesis by non-canonical Wnt signaling pathway	P	Any process that decreased the extent of cell adhesion that contributes to the shaping of the heart.
61343	cell adhesion involved in heart morphogenesis	P	The attachment of a cell, either to another cell or to an underlying substrate such as the extracellular matrix, via cell adhesion molecules that contributes to the shaping of the heart.
61344	regulation of cell adhesion involved in heart morphogenesis	P	Any process that modulates the extent of cell adhesion contributing to the shaping of the heart.
61345	planar cell polarity pathway involved in cardiac muscle cell fate commitment	P	The series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via effectors other than beta-catenin and contributing to a cardioblast being committed to a cardiac muscle cell fate.
61346	planar cell polarity pathway involved in heart morphogenesis	P	The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors including C-Jun N-terminal kinase (JNK) to modulate cytoskeletal elements and control cell polarity that contributes to the shaping of the heart.
61347	planar cell polarity pathway involved in outflow tract morphogenesis	P	The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors including C-Jun N-terminal kinase (JNK) to modulate cytoskeletal elements and control cell polarity that contributes to the shaping of the outflow tract.
61348	planar cell polarity pathway involved in ventricular septum morphogenesis	P	The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors including C-Jun N-terminal kinase (JNK) to modulate cytoskeletal elements and control cell polarity that contributes to the shaping of the ventricular septum.
61349	planar cell polarity pathway involved in cardiac right atrium morphogenesis	P	The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors including C-Jun N-terminal kinase (JNK) to modulate cytoskeletal elements and control cell polarity that contributes to the shaping of the cardiac right atrium.
61350	planar cell polarity pathway involved in cardiac muscle tissue morphogenesis	P	The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors including C-Jun N-terminal kinase (JNK) to modulate cytoskeletal elements and control cell polarity that contributes to the shaping of the cardiac muscle tissue.
61351	neural precursor cell proliferation	P	The multiplication or reproduction of neural precursor cells, resulting in the expansion of a cell population. A neural precursor cell is either a nervous system stem cell or a nervous system progenitor cell.
61352	cell chemotaxis involved in Malpighian tubule morphogenesis	P	The directed movement of the outgrowing Malpighian tubule guided by specific chemical cues/signals. Movement may be towards a guidance cue (positive chemotaxis) or away from it (negative chemotaxis). Guidance contributes to the final positioning of the tubule.
61353	BMP signaling pathway involved in Malpighian tubule cell chemotaxis	P	A series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, which contributes to the directed movement of a Malpighian tubule cell toward a stimulus, thereby contributing to the shaping of the tubule.
61354	planar cell polarity pathway involved in pericardium morphogenesis	P	The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors including C-Jun N-terminal kinase (JNK) to modulate cytoskeletal elements and control cell polarity that contributes to the shaping of the pericardium.
61355	Wnt protein secretion	P	The controlled release of a Wnt protein from a cell.
61356	regulation of Wnt protein secretion	P	Any process that modulates the frequency, rate or extent of the controlled release of a Wnt protein from a cell.
61357	positive regulation of Wnt protein secretion	P	Any process that activates or increases the frequency, rate or extent of the controlled release of a Wnt protein from a cell.
61358	negative regulation of Wnt protein secretion	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the controlled release of a Wnt protein from a cell.
61359	regulation of Wnt signaling pathway by Wnt protein secretion	P	Any process that modulates the frequency, rate or extent of the activity of the Wnt signaling pathway by the controlled release of a Wnt protein from a cell.
61360	optic chiasma development	P	The developmental process pertaining to the progression of the optic chiasm from its initial formation to the mature structure. The process begins when the pathfinding of the axons of the developing optic nerve cause some axons to cross at the midline of the brain and ends when the axons are mature.
61361	positive regulation of maintenance of bipolar cell polarity regulating cell shape	P	Any process that increases the frequency, rate or extent of maintenance of bipolar cell polarity regulating cell shape.
61362	negative regulation of maintenance of bipolar cell polarity regulating cell shape	P	Any process that decreases the frequency, rate or extent of maintenance of bipolar cell polarity regulating cell shape.
61363	negative regulation of progesterone biosynthesis involved in luteolysis	P	Any process that decreases the rate, frequency or extent of the biosynthesis of progesterone biosynthesis that contributes to luteolysis.
61364	apoptotic process involved in luteolysis	P	The apoptotic process that contributes to luteolysis.
61365	positive regulation of triglyceride lipase activity	P	Any process that increases the activity of triglyceride lipase.
61366	behavioral response to chemical pain	P	Any process that results in a change in the behaviour of an organism as a result of a chemical pain stimulus.
61367	behavioral response to acetic acid induced pain	P	Any process that results in a change in the behaviour of an organism as a result of an acetic acid pain stimulus.
61368	behavioral response to formalin induced pain	P	Any process that results in a change in the behaviour of an organism as a result of a formalin pain stimulus.
61369	negative regulation of testicular blood vessel morphogenesis	P	Any process that stops, prevents, or reduces the frequency, rate or extent of blood vessel morphogenesis in the testicle.
61370	testosterone biosynthetic process	P	The chemical reactions and pathways resulting in the formation of testosterone, an androgen having 17beta-hydroxy and 3-oxo groups, together with unsaturation at C-4 C-5.
61371	determination of heart left/right asymmetry	P	Determination of the asymmetric location of the heart with respect to the left and right halves of the organism.
61372	activin receptor signaling pathway involved in heart jogging	P	A series of molecular signals initiated by the binding of a member of the activin family to a receptor on the surface of a target cell, and contributing to the process of heart jogging.
61373	mammillary axonal complex development	P	The progression of the mammillary axonal complex over time, from its formation to the mature structure. The mammillary axonal complex is formed by the axons from the lateral, medial mammillary and the dorsal premammillary nuclei which share a branching pattern. Every neuron gives off one axonal stem that bifurcates into 2 branches. One of the branches is directed dorsally to the thalamus and another caudally to the midbrain.
61374	mammillothalamic axonal tract development	P	The progression of the mammillothalamic axonal tract, from its formation to the mature structure. The mammillothalamic tract is the collection of axons that connects the two major subdivisions of the diencephalon (hypothalamus and thalamus) and closes the diencephalic circuit.
61375	mammillotectal axonal tract development	P	The progression of the mammillotectal tract over time, from its formation to the mature structure. The mammillotectal tract is the collection of axons that connects the ventral diencephalon to the superior colliculus.
61376	mammillotegmental axonal tract development	P	The process in which the mammillotegmental tract progresses over time, from its formation to the mature structure. The mammillotegmental tract is the collection of axons that connects the ventral diencephalon to the tegmentum and pons.
61377	mammary gland lobule development	P	The progression of the mammary gland lobule over time, from its formation to the mature structure. A mammary gland lobule is a small rounded projection of the mammary gland.
61378	corpora quadrigemina development	P	The progression of the corpora quadrigemina over time, from its formation to the mature structure. The corpora quadrigemina is a part of the midbrain that is made up of the superior and inferior colliculi.
61379	inferior colliculus development	P	The process whose specific outcome is the progression of the inferior colliculus over time, from its formation to the mature structure. The inferior colliculus (IC) (Latin, lower hill) is the principal midbrain nucleus of the auditory pathway and receives input from several more peripheral brainstem nuclei in the auditory pathway, as well as inputs from the auditory cortex. The inferior colliculus has three subdivisions: the central nucleus (CIC), a dorsal cortex (DCIC) by which it is surrounded, and an external cortex (ICX) which is located laterally.
61380	superior colliculus development	P	The process whose specific outcome is the progression of the superior colliculus over time, from its formation to the mature structure. The superior colliculus is also known as the optic tectum or simply tectum and is a paired structure that forms a major component of the vertebrate midbrain.
61381	cell migration in diencephalon	P	The orderly movement of a cell that will reside in the diencephalon.
61382	Malpighian tubule tip cell differentiation	P	The process in which a relatively unspecialized cell acquires specialized features of a Malpighian tubule tip cell. A Malpighian tubule tip cell is a mitogenic signaling cell that controls the proliferation of its neighboring cells.
61383	trabecula morphogenesis	P	The process of shaping a trabecula in an organ. A trabecula is a small, often microscopic, tissue element in the form of a small beam, strut or rod, which generally has a mechanical function. Trabecula are usually but not necessarily, composed of dense collagenous tissue.
61384	heart trabecula morphogenesis	P	The process of shaping a trabecula in the heart. A trabecula is a small, often microscopic, tissue element in the form of a small beam, strut or rod, which generally has a mechanical function. Trabecula are usually but not necessarily, composed of dense collagenous tissue.
61385	fibroblast proliferation involved in heart morphogenesis	P	The multiplication or reproduction of fibroblasts, resulting in the expansion of a fibroblast population that contributes to the shaping of the heart.
61386	closure of optic fissure	P	The closure of the temporary ventral gap in the optic cup that contributes to its shaping.
61387	regulation of extent of cell growth	P	Any process that modulates the extent of cell growth.
61388	regulation of rate of cell growth	P	Any process that modulates the rate of cell growth.
61389	regulation of direction of cell growth	P	Any process that modulates the direction of cell growth.
61390	positive regulation of direction of cell growth	P	Any process that increases the direction of cell growth.
61391	negative regulation of direction of cell growth	P	Any process that decreases the direction of cell growth.
61392	regulation of transcription from RNA polymerase II promoter in response to osmotic stress	P	Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell.
61393	positive regulation of transcription from RNA polymerase II promoter in response to osmotic stress	P	Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell.
61394	regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance	P	Modulation of the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of an arsenic stimulus from compounds containing arsenic, including arsenates, arsenites, and arsenides.
61395	positive regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance	P	Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of an arsenic stimulus from compounds containing arsenic, including arsenates, arsenites, and arsenides.
61396	regulation of transcription from RNA polymerase II promoter in response to copper ion	P	Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter in response to an copper ion stimulus.
61397	positive regulation of transcription from RNA polymerase II promoter in response to copper ion	P	Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter in response to an copper ion stimulus.
61398	negative regulation of transcription from RNA polymerase II promoter in response to copper ion	P	Any process that decreases the frequency, rate or extent of transcription from an RNA polymerase II promoter in response to an copper ion stimulus.
61399	positive regulation of transcription from RNA polymerase II promoter in response to cobalt ion	P	Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter in response to a cobalt ion stimulus.
61400	positive regulation of transcription from RNA polymerase II promoter in response to calcium ion	P	Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter in response to a calcium ion stimulus.
61401	positive regulation of transcription from RNA polymerase II promoter in response to a hypotonic environment	P	Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of detection of, or exposure to, a decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment.
61402	positive regulation of transcription from RNA polymerase II promoter in response to acidic pH	P	Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a pH stimulus with pH < 7.
61403	positive regulation of transcription from RNA polymerase II promoter in response to nitrosative stress	P	Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a nitrosative stress stimulus. Nitrosative stress is a state often resulting from exposure to high levels of nitric oxide (NO) or the highly reactive oxidant peroxynitrite, which is produced following interaction of NO with superoxide anions.
61404	positive regulation of transcription from RNA polymerase II promoter in response to increased salt	P	Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of detection of, or exposure to, an increase in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment.
61405	positive regulation of transcription from RNA polymerase II promoter in response to hydrostatic pressure	P	Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a hydrostatic pressure stimulus. Hydrostatic pressure is the force acting on an object in a system where the fluid is at rest (as opposed to moving). The weight of the fluid above the object creates pressure on it.
61406	positive regulation of transcription from RNA polymerase II promoter in response to glucose starvation	P	Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of deprivation of glucose.
61407	positive regulation of transcription from RNA polymerase II promoter in response to hydrogen peroxide	P	Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a hydrogen peroxide (H2O2) stimulus.
61408	positive regulation of transcription from RNA polymerase II promoter in response to heat stress	P	Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.
61409	positive regulation of transcription from RNA polymerase II promoter in response to freezing	P	Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a freezing stimulus, temperatures below 0 degrees Celsius.
61410	positive regulation of transcription from RNA polymerase II promoter in response to ethanol	P	Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of an ethanol stimulus.
61411	positive regulation of transcription from RNA polymerase II promoter in response to cold	P	Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a cold stimulus, a temperature stimulus below the optimal temperature for that organism.
61412	positive regulation of transcription from RNA polymerase II promoter in response to amino acid starvation	P	Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of deprivation of amino acids.
61413	regulation of transcription from RNA polymerase II promoter by a nonfermentable carbon source	P	A transcription regulation process in which the presence of a nonfermentable carbon source leads to the modulation of the frequency, rate, or extent of transcription, from an RNA polymerase II promoter, of specific genes involved in the metabolism of other carbon sources.
61414	positive regulation of transcription from RNA polymerase II promoter by a nonfermentable carbon source	P	A transcription regulation process in which the presence of a nonfermentable carbon source leads to an increase of the frequency, rate, or extent of transcription, from an RNA polymerase II promoter, of specific genes involved in the metabolism of other carbon sources.
61415	negative regulation of transcription from RNA polymerase II promoter by a nonfermentable carbon source	P	A transcription regulation process in which the presence of a nonfermentable carbon source leads to a decrease of the frequency, rate, or extent of transcription, from an RNA polymerase II promoter, of specific genes involved in the metabolism of other carbon sources.
61416	regulation of transcription from RNA polymerase II promoter in response to salt stress	P	Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating the organism is under salt stress. The stress is usually an increase or decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment.
61417	negative regulation of transcription from RNA polymerase II promoter in response to oxidative stress	P	Any process that decreases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating the organism is under oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
61418	regulation of transcription from RNA polymerase II promoter in response to hypoxia	P	Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a hypoxia stimulus.
61419	positive regulation of transcription from RNA polymerase II promoter in response to hypoxia	P	Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a hypoxia stimulus.
61420	regulation of transcription from RNA polymerase II promoter in response to biotin starvation	P	Modulation of the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of deprivation of biotin.
61421	positive regulation of transcription by oleic acid	P	Any process involving oleic acid that activates or increases the rate of transcription.
61422	positive regulation of transcription from RNA polymerase II promoter in response to alkaline pH	P	Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a pH >7.0.
61423	positive regulation of sodium ion transport by positive regulation of transcription from RNA polymerase II promoter	P	Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter resulting in the increased frequency, rate or extent of the directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
61424	positive regulation of peroxisome organization by positive regulation of transcription from RNA polymerase II promoter	P	Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter and activates or increases the frequency, rate or extent of peroxisome organization.
61425	positive regulation of ethanol catabolic process by positive regulation of transcription from RNA polymerase II promoter	P	Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter and activates or increases the frequency, rate or extent of an ethanol catabolic process.
61426	positive regulation of sulfite transport by positive regulation of transcription from RNA polymerase II promoter	P	Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter and activates or increases the frequency, rate or extent of sulfite transport.
61427	negative regulation of ceramide biosynthetic process by negative regulation of transcription from RNA Polymerase II promoter	P	Any process that stops, prevents, or reduces the frequency, rate or extent of transcription from an RNA polymerase II promoter and stops, prevents or reduces the frequency, rate or extent of a ceramide biosynthetic process.
61428	negative regulation of transcription from RNA polymerase II promoter in response to hypoxia	P	Any process that decreases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a hypoxia stimulus.
61429	positive regulation of transcription from RNA polymerase II promoter by oleic acid	P	Any process involving oleic acid that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
61430	bone trabecula morphogenesis	P	The process of shaping a trabecula in bone. A trabecula is a tissue element in the form of a small beam, strut or rod.
61431	cellular response to methionine	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methionine stimulus.
61432	regulation of transcription from RNA polymerase II promoter in response to methionine	P	Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a methionine stimulus.
61433	cellular response to caloric restriction	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a of caloric restriction, insufficient food energy intake.
61434	regulation of replicative cell aging by regulation of transcription from RNA polymerase II promoter in response to caloric restriction	P	Any process that modulates the frequency, rate or extent of replicative cell aging through a mechanism that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a caloric restriction stimulus.
61435	positive regulation of transcription from a mobile element promoter	P	Any process that activates or increases the frequency, rate or extent of transcription from a mobile element promoter.
61436	establishment of skin barrier	P	Establishment of the epithelial barrier, the functional barrier in the skin that limits its permeability.
61437	renal system vasculature development	P	The process whose specific outcome is the progression of vasculature of the renal system over time, from its formation to the mature structure.
61438	renal system vasculature morphogenesis	P	The process in which the renal system vasculature is generated and organized. Morphogenesis pertains to the creation of form.
61439	kidney vasculature morphogenesis	P	The process in which the kidney vasculature is generated and organized. Morphogenesis pertains to the creation of form.
61440	kidney vasculature development	P	The process whose specific outcome is the progression of the vasculature of the kidney over time, from its formation to the mature structure.
61441	renal artery morphogenesis	P	The process in which the anatomical structure of a renal artery is generated and organized. Renal arteries supply the kidneys with blood.
61442	cardiac muscle cell fate determination	P	The process involved in cardiac muscle cell fate commitment. Once determination has taken place, a cell becomes committed to differentiate down a particular pathway regardless of its environment.
61443	endocardial cushion cell differentiation	P	The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of an endocardial cushion cell.
61444	endocardial cushion cell development	P	The process whose specific outcome is the progression of an endocardial cushion cell over time, from its formation to the mature state.
61445	endocardial cushion cell fate commitment	P	The commitment of a cell to an endocardial cushion cell fate and its capacity to differentiate into an endocardial cushion cell.
61446	endocardial cushion cell fate determination	P	The process involved in endocardial cushion cell fate commitment. Once determination has taken place, a cell becomes committed to differentiate down a particular pathway regardless of its environment.
61447	endocardial cushion cell fate specification	P	The process involved in the specification of endocardial cushion cell identity. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment.
61448	connective tissue development	P	The progression of a connective tissue over time, from its formation to the mature structure.
61449	olfactory bulb tufted cell development	P	The process whose specific outcome is the progression of an olfactory bulb tufted cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.
61450	trophoblast cell migration	P	Trophoblast cell migration that is accomplished by extension and retraction of a pseudopodium. Trophoblast cells line the outside of the blastocyst.
61451	retrotrapezoid nucleus development	P	The progression of the retrotrapezoid nucleus (RTN) over time from it's initial formation to its mature state. The retrotrapezoid nucleus is a group of neurons in the rostral medulla, which are responsible regulating respiration.
61452	retrotrapezoid nucleus neuron differentiation	P	The process in which a relatively unspecialized cell acquires specialized features of a neuron whose cell body resides in the retrotrapezoid nucleus.
61453	interstitial cell of Cajal differentiation	P	The process in which a relatively unspecialized cell acquires specialized features of an interstitial cell of Cajal. An interstitial cell of Cajal is an intestinal neuroepithelial cell that serves as a pacemaker to trigger gut contraction.
61454	Golgi calcium ion export	P	The directed movement of calcium ions (Ca2+) out of the Golgi apparatus into the cytosol.
61455	integral component of muscle cell projection membrane	C	The component of the muscle cell projection membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
61456	mesenchymal stem cell migration involved in uteric bud morphogenesis	P	The orderly movement of a mesenchymal stem cell from one site to another contributing to the shaping of the ureteric bud. A mesenchymal stem cell, or MSC, is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells.
61457	mesonephric cell migration involved in male gonad development	P	The orderly movement of a cell from the mesonephros to the male gonad, contributing to its development.
61458	reproductive system development	P	The progression of the reproductive system over time from its formation to the mature structure. The reproductive system consists of the organs that function in reproduction.
61459	L-arginine transmembrane transporter activity	F	Enables the stereospecific transfer of L-arginine, 2-amino-5-guanidinopentanoic acid, across a biological membrane.
61460	L-histidine import	P	The directed movement of L-histidine into a cell or organelle.
61461	L-lysine import	P	The directed movement of L-lysine into a cell or organelle.
61462	protein localization to lysosome	P	A process in which a protein is transported to, or maintained in, a location within a lysosome.
61463	O-acetyl-ADP-ribose deacetylase activity	F	Catalysis of the reaction O-acetyl-ADP-ribose + H2O = ADP-ribose + acetate.
61464	plasma membrane part of cell-substrate junction.	C	The part of the plasma membrane that contributes to the structure of a cell-substrate junction.
61465	plasma membrane part of hemidesmosome	C	The part of the plasma membrane that contributes to the structure of a hemidesmosome.
61466	plasma membrane part of cell junction	C	The part of the plasma membrane that contributes to the structure of a cell junction.
61467	basolateral protein localization	P	Any process in which a protein is transported to, or maintained in, basolateral regions of the cell.
61468	karyomere	C	A membrane-bound intermediate cleavage-stage structure of individual or groups of chromosomes that coalesces and fuses with other karyomeres to form a nucleus during interphase. Karyomere formation occurs in blastomeres undergoing rapid cell division.
61469	regulation of type B pancreatic cell proliferation	P	Any process that modulates the frequency, rate or extent of type B pancreatic cell proliferation.
61470	T follicular helper cell differentiation	P	The process in which a relatively unspecialized T cell acquires specialized features of a mature T follicular helper cell.
61471	karyomere assembly	P	The process where the nuclear membrane engulfs condensed chromosomes to form karyomeres during M phase of the mitotic cell cycle.
61472	karyomere membrane fusion	P	Process whereby karyomere membranes fuse during interphase to form a single lobed nucleus.
61473	murein tripeptide carboxypeptidase activity	F	Catalysis of the reaction L-Ala-gamma;-D-Glu-meso-Dap (murein tripeptide) + H2O = L-Ala-&gamma;-D-Glu + meso-diaminopimelate.
61474	phagolysosome membrane	C	The lipid bilayer surrounding a phagolysosome.
61475	cytosolic valyl-tRNA aminoacylation	P	The process of coupling valine to valyl-tRNA in the cytosol, catalyzed by valyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.
61476	response to anticoagulant	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an anticoagulant stimulus.
61477	response to aromatase inhibitor	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an aromatase inhibitor stimulus.
61478	response to platelet aggregation inhibitor	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a platelet aggregation inhibitor stimulus.
61479	response to reverse transcriptase inhibitor	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a reverse transcriptase inhibitor stimulus.
61480	response to asparaginase	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an asparaginase stimulus.
61481	response to TNF agonist	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a TNF agonist stimulus.
61482	response to irinotecan	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an irinotecan stimulus.
61483	sulfinylpropanyl adenylate synthase	F	Catalysis of the reaction: cysteine sulfanate + GTP + IMP = sulfinylpropanyl adenylate + GDP + 3 H(+) + phosphate.
61484	hematopoietic stem cell homeostasis	P	Any biological process involved in the maintenance of the steady-state number of hematopoietic stem cells within a population of cells.
61485	memory T cell proliferation	P	The expansion of a memory T cell population by cell division.
61486	high-affinity fructose transmembrane transporter activity	F	Catalysis of the transfer of fructose from one side of a membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.
61487	DNA replication initiation from late origin	P	The process in which DNA-dependent DNA replication is started at a late origin of replication. A late origin of replication refers to an origin that is activated late in S phase.
61488	adenine import into cell	P	The directed movement of adenine from outside of a cell into the cytoplasmic compartment. This may occur via transport across the plasma membrane or via endocytosis.
61489	guanine import into cell	P	The directed movement of guanine from outside of a cell into the cytoplasmic compartment. This may occur via transport across the plasma membrane or via endocytosis.
61490	glucose import into cell	P	The directed movement of glucose from outside of a cell into the cytoplasmic compartment. This may occur via transport across the plasma membrane or via endocytosis.
61491	serine import into cell	P	The directed movement of serine from outside of a cell into the cytoplasmic compartment. This may occur via transport across the plasma membrane or via endocytosis.
61492	asymmetric protein localization to old or new spindle pole body	P	Any process in which a protein is transported to, or maintained to either the old or new spindle pole body resulting in its being distributed asymmetrically.
61493	central plaque of mitotic spindle pole body	C	One of three laminate structures that form the mitotic spindle pole body; the central plaque is embedded in the nuclear envelope.
61494	gamma-tubulin large complex, mitotic spindle pole body	C	A complex of gamma tubulin and associated proteins thought to be formed by multimerization of gamma-tubulin small complexes located in the mitotic spindle pole body.
61495	gamma-tubulin small complex, mitotic spindle pole body	C	A complex composed of two gamma-tubulin molecules and conserved non-tubulin proteins located in the mitotic spindle pole body and isolated by fractionation from cells. The complex, approximately 6S-9S, is analogous to the small complex in animal cells but contains fewer subunits, and is not thought to multimerize into larger functional units, like complexes in those organisms. An example of this structure is found in Saccharomyces cerevisiae.
61496	half bridge of mitotic spindle pole body	C	Structure adjacent to the plaques of the mitotic spindle pole body.
61497	inner plaque of mitotic spindle pole body	C	One of three laminate structures that form the mitotic spindle pole body; the inner plaque is in the nucleus.
61498	intermediate layer of mitotic spindle pole body	C	Structure between the central and outer plaques of the mitotic spindle pole body.
61499	outer plaque of mitotic spindle pole body	C	One of three laminate structures that form the mitotic spindle pole body; the outer plaque is in the cytoplasm.
61500	gene conversion at mating-type locus, termination of copy-synthesis	P	A DNA replication termination process that is part of gene conversion at a mating-type locus and takes place at a specific termination site.
61501	cyclic-GMP-AMP synthase activity	F	Catalysis of the reaction: ATP + GTP = 2 diphosphate + cyclic GMP-AMP.
61502	early endosome to recycling endosome transport	P	The directed movement of substances, in membrane-bounded vesicles, from the early sorting endosomes to the recycling endosomes.
61503	tRNA threonylcarbamoyladenosine dehydratase	F	Catalysis of the ATP-dependent dehydration of t6A to form cyclic t6A.
61504	cyclic threonylcarbamoyladenosine biosynthetic process	P	The chemical reactions and pathways resulting in the formation of cyclic threonylcarbamoyladenosine, a modified nucleoside found in some tRNA molecules.
61505	DNA topoisomerase II activity	F	Catalysis of a DNA topological transformation by transiently cleaving a pair of complementary DNA strands to form a gate through which a second double-stranded DNA segment is passed, after which the severed strands in the first DNA segment are rejoined; changes the linking number in multiples of 2.
61506	DNA topoisomerase type II (ATP-independent) activity	F	Catalysis of a DNA topological transformation by transiently cleaving a pair of complementary DNA strands to form a gate through which a second double-stranded DNA segment is passed, after which the severed strands in the first DNA segment are rejoined; product release is not coupled to ATP binding and hydrolysis; changes the linking number in multiples of 2.
61507	cyclic-GMP-AMP binding	F	Interacting selectively and non-covalently with cyclic-GMP-AMP (cGAMP) cyclic nucleotide.
61508	CDP phosphorylation	P	The process of introducing a phosphate group into CDP to produce a CTP.
61509	asymmetric protein localization to old mitotic spindle pole body	P	Any process in which a protein is transported to, or maintained to the old mitotic spindle pole body resulting in its being distributed asymmetrically.
61510	asymmetric protein localization to new mitotic spindle pole body	P	Any process in which a protein is transported to, or maintained to the new mitotic spindle pole body resulting in its being distributed asymmetrically.
61511	centriole elongation	P	The centrosome organization process by which a centriole increases in length as part of the process of replication.
61512	protein localization to cilium	P	A process in which a protein is transported to, or maintained in, a location within a cilium.
61513	glucose 6-phosphate:inorganic phosphate antiporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucose 6-phosphate(out) + inorganic phosphate(in) = glucose 6-phosphate(in) + inorganic phosphate(out).
61514	interleukin-34-mediated signaling pathway	P	A series of molecular signals initiated by the binding of interleukin-34 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.
61515	myeloid cell development	P	The process whose specific outcome is the progression of a myeloid cell over time, from its formation to the mature structure.
61516	monocyte proliferation	P	The expansion of a monocyte population by cell division.
61517	macrophage proliferation	P	The expansion of a macrophage population by cell division.
61518	microglial cell proliferation	P	The expansion of a microglial cell population by cell division.
61519	macrophage homeostasis	P	The process of regulating the proliferation and elimination of macrophage cells such that the total number of myeloid cells within a whole or part of an organism is stable over time in the absence of an outside stimulus.
61520	Langerhans cell differentiation	P	The process in which a precursor cell type acquires the specialized features of a Langerhans cell.
61521	hepatic stellate cell differentiation	P	The process in which a relatively unspecialized cell acquires the specialized structural and/or functional features of a hepatic stellate cell.
61522	1,4-dihydroxy-2-naphthoyl-CoA thioesterase activity	F	Catalysis of the reaction 1,4-dihydroxy-2-naphthoyl-CoA + H2O = 1,4-dihydroxy-2-naphthoate + CoA.
61523	cilium disassembly	P	A cellular process that results in the breakdown of a cilium.
61524	central canal development	P	The process whose specific outcome is the formation of the central canal of the spinal cord from its formation to the mature structure. The central canal is a spinal cord structure that is part of the ventricular system and is filled with cerebral-spinal fluid and runs the length of the spinal cord.
61525	hindgut development	P	The process whose specific outcome is the progression of the hindgut over time, from its formation to the mature structure. The hindgut is part of the alimentary canal that lies posterior to the midgut.
61526	acetylcholine secretion	P	The regulated release of acetylcholine by a cell.
61527	dopamine secretion, neurotransmission	P	The regulated release of dopamine by a cell in which the dopamine acts as a neurotransmitter.
61528	aspartate secretion	P	The regulated release of aspartate by a cell.
61529	epinephrine secretion, neurotransmission	P	The regulated release of epinephrine by a cell in which the epinephrine acts as a neurotransmitter.
61530	aspartate secretion, neurotransmission	P	The regulated release of aspartate by a cell in which the aspartate acts as a neurotransmitter.
61531	primary amine secretion	P	The regulated release of a primary amine by a cell.
61532	primary amine secretion, neurotransmission	P	The regulated release of a primary amine by a cell, in which the primary amine acts as a neurotransmitter.
61533	norepinephrine secretion, neurotransmission	P	The regulated release of norepinephrine by a cell, in which the norepinephrine acts as a neurotransmitter.
61534	gamma-aminobutyric acid secretion, neurotransmission	P	The regulated release of gamma-aminobutyric acid by a cell, in which the gamma-aminobutyric acid acts as a neurotransmitter.
61535	glutamate secretion, neurotransmission	P	The controlled release of glutamate by a cell, in which the glutamate acts as a neurotransmitter.
61536	glycine secretion	P	The controlled release of glycine by a cell.
61537	glycine secretion, neurotransmission	P	The controlled release of glycine by a cell, in which glycine acts as a neurotransmitter.
61538	histamine secretion, neurotransmission	P	The controlled release of histamine by a cell, in which the histamine acts as a neurotransmitter.
61539	octopamine secretion	P	The controlled release of octopamine by a cell.
61540	octopamine secretion, neurotransmission	P	The controlled release of octopamine by a cell, in which the octopamine acts as a neurotransmitter.
61541	rhabdomere morphogenesis	P	The process in which the anatomical structures of a rhabdomere are generated and organized. The rhabdomere is the organelle on the apical surface of a photoreceptor cell that contains the visual pigments.
61542	3-demethylubiquinone-n 3-O-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + 3-demethylubiquinone-n = S-adenosyl-L-homocysteine + ubiquinone-n.
61543	3-demethylubiquinone-6 3-O-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + 3-demethylubiquinone-6 = S-adenosyl-L-homocysteine + ubiquinone-6.
61544	peptide secretion, neurotransmission	P	The controlled release of a peptide from a cell in which the peptide acts as a neurotransmitter.
61545	tyramine secretion	P	The regulated release of a tyramine by a cell.
61546	tyramine secretion, neurotransmission	P	The regulated release of a tyramine by a cell in which the tyramine acts as a neurotransmitter.
61547	glycogen synthase activity, transferring glucose-1-phosphate	F	Catalysis of the reaction: UDP-glucose + (1,4)-alpha-D-glucosyl(n) = UMP + (1,4)-alpha-D-glucosyl(n)-glucose-1-phosphate.
61548	ganglion development	P	The process whose specific outcome is the progression of a ganglion over time, from its formation to the mature structure.
61549	sympathetic ganglion development	P	The process whose specific outcome is the progression of a sympathetic ganglion over time, from its formation to the mature structure.
61550	cranial ganglion development	P	The process whose specific outcome is the progression of a cranial ganglion over time, from its formation to the mature structure.
61551	trigeminal ganglion development	P	The process whose specific outcome is the progression of a trigeminal ganglion over time, from its formation to the mature structure.
61552	ganglion morphogenesis	P	The process in which the anatomical structures of ganglion are generated and organized.
61553	ganglion maturation	P	A developmental process, independent of morphogenetic (shape) change, that is required for ganglion to attain its fully functional state.
61554	ganglion formation	P	The process that gives rise to ganglion. This process pertains to the initial formation of a structure from unspecified parts.
61555	ganglion structural organization	P	The process that contributes to creating the structural organization of a ganglion. This process pertains to the physical shaping of a rudimentary structure.
61556	trigeminal ganglion morphogenesis	P	The process in which the anatomical structure of a trigeminal ganglion is generated and organized.
61557	trigeminal ganglion maturation	P	A developmental process, independent of morphogenetic (shape) change, that is required for a trigeminal ganglion to attain its fully functional state.
61558	cranial ganglion maturation	P	A developmental process, independent of morphogenetic (shape) change, that is required for a cranial ganglion to attain its fully functional state.
61559	cranial ganglion morphogenesis	P	The process in which the anatomical structure of a cranial ganglion is generated and organized.
61560	cranial ganglion formation	P	The process that gives rise to a cranial ganglion. This process pertains to the initial formation of a structure from unspecified parts.
61561	trigeminal ganglion formation	P	The process that gives rise to the trigeminal ganglion. This process pertains to the initial formation of a structure from unspecified parts.
61562	cranial ganglion structural organization	P	The process that contributes to creating the structural organization of a cranial ganglion. This process pertains to the physical shaping of a rudimentary structure.
61563	trigeminal ganglion structural organization	P	The process that contributes to creating the structural organization of the trigeminal ganglion This process pertains to the physical shaping of a rudimentary structure.
61564	axon development	P	The progression of an axon over time. Covers axonogenesis (de novo generation of an axon) and axon regeneration (regrowth), as well as processes pertaining to the progression of the axon over time (fasciculation and defasciculation).
61565	dAMP phosphorylation	P	The process of introducing a phosphate group into dAMP, deoxyadenosine monophosphate, to produce dADP. Addition of two phosphate groups produces dATP.
61566	CMP phosphorylation	P	The process of introducing a phosphate group into CMP, cytidine monophosphate, to produce CDP. Addition of two phosphate groups produces CTP.
61567	dCMP phosphorylation	P	The process of introducing a phosphate group into dCMP, deoxycytidine monophosphate, to produce dCDP. Addition of two phosphate groups produces dCTP.
61568	GDP phosphorylation	P	The process of introducing a phosphate group into GDP, guanosine diphosphate, to produce GTP.
61569	UDP phosphorylation	P	The process of introducing a phosphate group into UDP, uridine diphosphate, to produce UTP.
61570	dCDP phosphorylation	P	The process of introducing a phosphate group into dCDP to produce a dCTP.
61571	TDP phosphorylation	P	The process of introducing a phosphate group into TDP to produce a TTP.
61572	actin filament bundle organization	P	A process that results in the assembly, arrangement of constituent parts, or disassembly of an actin filament bundle.
61573	actin filament bundle retrograde transport	P	A process of actin filament bundle distribution that results in the arrangement of actin filament bundles from the periphery toward the interior of the cell.
61574	ASAP complex	C	A protein complex involved in regulation of mRNA processing and apoptosis. It binds to RNA in a sequence-independent manner and is recruited to the EJC prior to or during the splicing process. In humans the core proteins are RNPS1, SAP18 and ACIN1.
61575	cyclin-dependent protein serine/threonine kinase activator activity	F	Binds to and increases the activity of a cyclin-dependent protein serine/threonine kinase.
61576	acyl-CoA ceramide synthase complex	C	A protein complex that catalyzes the reaction acyl-CoA + sphingosine = CoA + N-acylsphingosine. In S. cerevisiae it contains three subunits: lag1, lac1 and lip1.
61577	calcium ion transmembrane transport via high voltage-gated calcium channel	P	A process in which a calcium ion is transported from one side of a membrane to the other by means of a high voltage-gated calcium channel.
61578	Lys63-specific deubiquitinase activity	F	Hydrolysis of Lys63-Linked ubiquitin unit(s) from a ubiquitinated protein.
61579	N-acyl homoserine lactone synthase activity	F	Catalyzing the reaction: acyl-[acyl-carrier-protein] + S-adenosyl-L-methionine -> [acyl-carrier- protein] + S-methyl-5'-thioadenosine + N-acyl-L-homoserine lactone.
61580	colon epithelial cell migration	P	The orderly movement of a colonic epithelial cell from one site to another, often during the development of a multicellular organism.
61581	corneal epithelial cell migration	P	The orderly movement of a corneal epithelial cell from one site to another, often during the development of a multicellular organism.
61582	intestinal epithelial cell migration	P	The orderly movement of an intestinal epithelial cell from one site to another, often during the development of a multicellular organism.
61583	colon epithelial cell chemotaxis	P	The directed movement of a colon epithelial cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis).
61584	hypocretin secretion	P	The controlled release of hypocretin from a cell or a tissue.
61585	hypocretin secretion, neurotransmission	P	The controlled release of a peptide from a cell or a tissue in which the peptide acts as a neurotransmitter.
61586	positive regulation of transcription by transcription factor localization	P	Any process that activates or increases the frequency, rate or extent of DNA-dependent transcription using a mechanism that involves the localization of a transcription factor.
61587	transfer RNA gene-mediated silencing	P	The chromatin silencing that results in the inhibition of RNA polymerase II-transcribed genes located in the vicinity of tRNA genes.
61588	calcium activated phospholipid scrambling	P	The movement of a population of phospholipid molecules from one leaflet of the plasma membrane bilayer to the opposite leaflet as a result of a calcium stimulus.
61589	calcium activated phosphatidylserine scrambling	P	The movement of a population of phosphatidylserine molecules from one leaflet of the plasma membrane bilayer to the opposite leaflet as a result of a calcium stimulus.
61590	calcium activated phosphatidylcholine scrambling	P	The movement of a population of phosphatidylcholine molecules from one leaflet of the plasma membrane bilayer to the opposite leaflet as a result of a calcium stimulus.
61591	calcium activated galactosylceramide scrambling	P	The movement of a population of galactosylceramide molecules from one leaflet of the plasma membrane bilayer to the opposite leaflet as a result of a calcium stimulus.
61592	phosphatidylserine exposure on osteoblast involved in bone mineralization	P	A phospholipid scrambling process that results in the appearance of phosphatidylserine on the surface of osteoblasts, and contributes to bone mineralization.
61593	sulfoquinovose isomerase activity	F	Catalysis of the reaction sulfoquinovose = 6-deoxy-6-sulfofructose.
61594	6-deoxy-6-sulfofructose kinase activity	F	Catalysis of the reaction 6-deoxy-6-sulfofructose + ATP = 6-deoxy-6-sulfofructose-1-phosphate + ADP.
61595	6-deoxy-6-sulfofructose-1-phosphate aldolase activity	F	Catalysis of the reaction 6-deoxy-6-sulfofructose-1-phosphate = 3-sulfolactaldehyde + dihydroxyacetone phosphate.
61596	3-sulfolactaldehyde reductase activity	F	Catalysis of the reaction 2,3-dihydroxypropane-1-sulfonate + NAD+ = 3-sulfolactaldehyde + NADH + H+.
61598	molybdopterin adenylyltransferase activity	F	Catalysis of the reaction ATP + molybdopterin = diphosphate + adenylyl-molybdopterin.
61599	molybdopterin molybdotransferase activity	F	Catalysis of the reaction adenylyl-molybdopterin + molybdate = molybdenum cofactor + AMP.
61602	molybdenum cofactor cytidylyltransferase activity	F	Catalysis of the reaction CTP + molybdenum cofactor = diphosphate + cytidylyl molybdenum cofactor.
61603	molybdenum cofactor guanylyltransferase activity	F	Catalysis of the reaction GTP + molybdenum cofactor = diphosphate + guanylyl molybdenum cofactor.
61604	molybdopterin-synthase sulfurtransferase activity	F	Catalysis of the reaction: [Molybdopterin-synthase sulfur-carrier protein]-Gly-Gly-AMP + [cysteine desulfurase]-S-sulfanyl-L-cysteine <=> AMP [molybdopterin-synthase sulfur-carrier protein]-Gly-NH-CH(2)-C(O)SH + cysteine desulfurase.
61605	molybdopterin-synthase adenylyltransferase activity	F	Catalysis of the reaction: ATP [molybdopterin-synthase sulfur-carrier protein]-Gly-Gly = diphosphate [molybdopterin-synthase sulfur-carrier protein]-Gly-Gly-AMP.
61606	N-terminal protein amino acid propionylation	P	The propionylation of the N-terminal amino acid of proteins.
61607	peptide alpha-N-propionyltransferase activity	F	Catalysis of the reaction: propionyl-CoA + peptide = CoA + N-alpha-propionylpeptide. This reaction is the propionylation of the N-terminal amino acid residue of a peptide or protein.
61608	nuclear import signal receptor activity	F	Combining with a nuclear import signal (NIS) to mediate transport of the NIS-containing protein through the nuclear pore to the nucleus.
61609	fructose-1-phosphate aldolase activity	F	Catalysis of the reaction: D-fructose-1-phosphate = dihydroxyacetone phosphate + D-glyceraldehyde.
61610	glycerol to glycerone phosphate metabolic process	P	The chemical reactions and pathways in which glycerol, 1,2,3-propanetriol, is converted to glycerone phosphate.
61611	mannose to fructose-6-phosphate metabolic process	P	The chemical reactions and pathways in which mannose, the aldohexose manno-hexose, is converted to fructose-6-phosphate.
61612	galactose to glucose-1-phosphate metabolic process	P	The chemical reactions and pathways in which galactose, the aldohexose galacto-hexose, is converted to glucose-1-phosphate.
61613	glycolytic process from glycerol	P	The glycolytic process in which glycerol is catabolized to pyruvate generating ATP and NADH.
61614	pri-miRNA transcription from RNA polymerase II promoter	P	The cellular synthesis of primary microRNA (pri-miRNA) transcripts from a DNA template by RNA polymerase II, originating at an RNA polymerase II promoter. pri-miRNA transcripts are subsequently processed to produce the ~22nt miRNAs that function in gene regulation.
61615	glycolytic process through fructose-6-phosphate	P	The chemical reactions and pathways resulting in the breakdown of a monosaccharide into pyruvate, occurring through a fructose-6-phosphate intermediate, with the concomitant production of ATP and NADH.
61616	glycolytic process from fructose through fructose-6-phosphate	P	The glycolytic process through fructose-6-phosphate in which fructose is catabolized into pyruvate.
61617	MICOS complex	C	Mitochondrial inner membrane complex involved in maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. In Saccharomyces cerevisiae the complex has six subunits: MIC10, MIC12, MIC19, MIC26, MIC27, and MIC60.
61618	sublamina densa	C	The part of the basement membrane that lies beneath the lamina densa, containing anchoring fibrils, anchoring plaques, collagen fibers, and elastic fibers.
61619	glycolytic process from mannose through fructose-6-phosphate	P	The chemical reactions and pathways resulting in the breakdown of mannose into pyruvate, occurring through a fructose-6-phosphate intermediate, with the concomitant production of ATP and NADH.
61620	glycolytic process through glucose-6-phosphate	P	The chemical reactions and pathways resulting in the breakdown of a carbohydrate into pyruvate, occurring through a glucose-6-phosphate intermediate, with the concomitant production of a small amount of ATP.
61621	canonical glycolysis	P	The glycolytic process that begins with the conversion of glucose to glucose-6-phosphate by glucokinase activity. Glycolytic processes are the chemical reactions and pathways resulting in the breakdown of a carbohydrate into pyruvate, with the concomitant production of a small amount of ATP.
61622	glycolytic process through glucose-1-phosphate	P	The chemical reactions and pathways through a glucose-1-phosphate intermediate that result in the catabolism of a carbohydrate into pyruvate, with the concomitant production of a small amount of ATP.
61623	glycolytic process from galactose	P	The chemical reactions and pathways resulting in the breakdown of galactose into pyruvate, with the concomitant production of a small amount of ATP.
61624	fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate	P	The chemical reactions and pathways resulting in the breakdown of fructose that results in the formation of dihydroxyacetone phosphate and glyceraldehyde-3-phosphate.
61625	glycolytic process through fructose-1-phosphate	P	The chemical reactions and pathways resulting in the breakdown of fructose into pyruvate through a fructose-1-phosphate intermediate, with the concomitant production of ATP and NADH.
61626	pharyngeal arch artery morphogenesis	P	The process in which the anatomical structures of a pharyngeal arch artery is generated and organized. The pharyngeal arch arteries are a series of six paired embryological vascular structures, the development of which give rise to several major arteries, such as the stapedial artery, the middle meningeal artery, the internal carotid artery and the pulmonary artery.
61627	S-methylmethionine-homocysteine S-methyltransferase activity	F	Catalysis of the reaction: S-methyl-L-methionine + L-homocysteine = 2 L-methionine + H+.
61628	H3K27me3 modified histone binding	F	Interacting selectively and non-covalently with a histone H3 in which the lysine residue at position 27 has been modified by trimethylation.
61629	RNA polymerase II sequence-specific DNA binding transcription factor binding	F	Interacting selectively and non-covalently with a sequence-specific DNA binding RNA polymerase II transcription factor, any of the factors that interact selectively and non-covalently with a specific DNA sequence in order to modulate transcription.
61630	ubiquitin protein ligase activity	F	Catalysis of the transfer of ubiquitin to a substrate protein via the reaction X-ubiquitin + S -> X + S-ubiquitin, where X is either an E2 or E3 enzyme, the X-ubiquitin linkage is a thioester bond, and the S-ubiquitin linkage is an amide bond: an isopeptide bond between the C-terminal glycine of ubiquitin and the epsilon-amino group of lysine residues in the substrate or, in the linear extension of ubiquitin chains, a peptide bond the between the C-terminal glycine and N-terminal methionine of ubiquitin residues.
61631	ubiquitin conjugating enzyme activity	F	Isoenergetic transfer of ubiquitin from one protein to another via the reaction X-ubiquitin + Y -> Y-ubiquitin + X, where both the X-ubiquitin and Y-ubiquitin linkages are thioester bonds between the C-terminal glycine of ubiquitin and a sulfhydryl side group of a cysteine residue.
61632	RNA lariat debranching enzyme activator activity	F	Increases the activity of an enzyme that catalyzes the hydrolysis of branched RNA structures that contain vicinal 2'-5'- and 3'-5'-phosphodiester bonds at a branch point nucleotide.
61633	transport-coupled glycolytic process through glucose-6-phosphate	P	The chemical reactions and pathways resulting in the breakdown of glucose into pyruvate, in which the glucose is converted to glucose-6-phosphate intermediate coupled to transmembrane transport.
61634	alpha-D-xyloside xylohydrolase	F	Catalysis of the hydrolysis of terminal, non-reducing alpha-D-xylose residues with release of alpha-D-xylose.
61635	regulation of protein complex stability	P	Any process that affects the structure and integrity of a protein complex by altering the likelihood of its assembly or disassembly.
61638	CENP-A containing chromatin	C	The specialized chromatin located the centromeric core region or the entire centromeric region in organisms with point centromeres, which is enriched for CENP-A-containing nucleosomes. This chromatin forms a 3-dimensional structure which provides a platform for kinetochore assembly and microtubule attachment.
61639	Cdv-dependent cytokinesis	P	A cytokinesis that involves a set of conserved proteins including the Cdv proteins, and results in the formation of two similarly sized and shaped cells.
61640	cytoskeleton-dependent cytokinesis	P	A cytokinesis that involves the function of a set of proteins that are part of the microfilament or microtubule cytoskeleton.
61641	CENP-A containing chromatin organization	P	Any process that results in the specification, formation or maintenance of the physical structure of CENP-A containing chromatin.
61642	chemoattraction of axon	P	The process in which a neuron growth cone is directed to a specific target site in response to an attractive chemical signal.
61643	chemorepulsion of axon	P	The process in which a neuron growth cone is directed to a specific target site in response to a repulsive chemical cue.
61644	protein localization to CENP-A containing chromatin	P	Any process in which a protein is transported to, or maintained at, CENP-A containing chromatin.
61645	endocytic patch	C	The part of the cell cortex consisting of an aggregation of proteins that will give rise to an endocytic vesicle.
61646	positive regulation of glutamate neurotransmitter secretion in response to membrane depolarization	P	Any process that activates or increases the frequency, rate or extent of glutamate secretion in response to membrane depolarization, where glutamate acts as a neurotransmitter.
61647	histone H3-K9 modification	P	The modification of histone H3 at a lysine in position 9 of the histone.
61648	tooth replacement	P	The process whose specific outcome is the replacement of an existing tooth with another tooth.
61649	ubiquitinated histone binding	F	Interacting selectively and non-covalently with a histone protein in which a residue has been modified by ubiquitination. Histones are any of a group of water-soluble proteins found in association with the DNA of plant and animal chromosomes.
61650	ubiquitin-like protein conjugating enzyme activity	F	Isoenergetic transfer of a ubiquitin-like protein (ULP) from one protein to another via the reaction X-SCP + Y -> Y-SCP + X, where both the X-SCP and Y-SCP linkages are thioester bonds between the C-terminal amino acid of SCP and a sulfhydryl side group of a cysteine residue.
61651	Atg12 conjugating enzyme activity	F	Isoenergetic transfer of Atg12 from one protein to another via the reaction X-Atg12 + Y -> Y-Atg12 + X, where both the X-Atg12 and Y-Atg12 linkages are thioester bonds between the C-terminal amino acid of Atg12 and a sulfhydryl side group of a cysteine residue.
61652	FAT10 conjugating enzyme activity	F	Isoenergetic transfer of FAT10 from one protein to another via the reaction X-FAT10 + Y -> Y-FAT10 + X, where both the X-FAT10 and Y-FAT10 linkages are thioester bonds between the C-terminal amino acid of FAT10 and a sulfhydryl side group of a cysteine residue.
61653	ISG15 conjugating enzyme activity	F	Isoenergetic transfer of ISG15 from one protein to another via the reaction X-ISG15 + Y -> Y-ISG15 + X, where both the X-ISG15 and Y-ISG15 linkages are thioester bonds between the C-terminal amino acid of ISG15 and a sulfhydryl side group of a cysteine residue.
61654	NEDD8 conjugating enzyme activity	F	Isoenergetic transfer of NEDD8 from one protein to another via the reaction X-NEDD8 + Y -> Y-NEDD8 + X, where both the X-NEDD8 and Y-NEDD8 linkages are thioester bonds between the C-terminal amino acid of NEDD8 and a sulfhydryl side group of a cysteine residue.
61655	Pup conjugating enzyme activity	F	Isoenergetic transfer of Pup from one protein to another via the reaction X-Pup + Y -> Y-Pup + X, where both the X-Pup and Y-Pup linkages are thioester bonds between the C-terminal amino acid of Pup and a sulfhydryl side group of a cysteine residue.
61656	SUMO conjugating enzyme activity	F	Isoenergetic transfer of SUMO from one protein to another via the reaction X-SUMO + Y -> Y-SUMO + X, where both the X-SUMO and Y-SUMO linkages are thioester bonds between the C-terminal amino acid of SUMO and a sulfhydryl side group of a cysteine residue.
61657	UFM1 conjugating enzyme activity	F	Isoenergetic transfer of UFM1 from one protein to another via the reaction X-UFM1 + Y -> Y-UFM1 + X, where both the X-UFM1 and Y-UFM1 linkages are thioester bonds between the C-terminal amino acid of UFM1 and a sulfhydryl side group of a cysteine residue.
61658	URM1 conjugating enzyme activity	F	Isoenergetic transfer of URM1 from one protein to another via the reaction X-URM1 + Y -> Y-URM1 + X, where both the X-URM1 and Y-URM1 linkages are thioester bonds between the C-terminal amino acid of URM1 and a sulfhydryl side group of a cysteine residue.
61659	ubiquitin-like protein ligase activity	F	Catalysis of the transfer of a ubiquitin-like protein (ULP) to a substrate protein via the reaction X-ULP + S --> X + S-ULP, where X is either an E2 or E3 enzyme, the X-ULP linkage is a thioester bond, and the S-ULP linkage is an isopeptide bond between the C-terminal glycine of ULP and the epsilon-amino group of lysine residues in the substrate.
61660	Atg12 ligase activity	F	Catalysis of the transfer of Atg12 to a substrate protein via the reaction X-Atg12 + S --> X + S-Atg12, where X is either an E2 or E3 enzyme, the X-Atg12 linkage is a thioester bond, and the S-Atg12 linkage is an isopeptide bond between the C-terminal amino acid of Atg12 and the epsilon-amino group of lysine residues in the substrate.
61661	FAT10 ligase activity	F	Catalysis of the transfer of FAT10 to a substrate protein via the reaction X-FAT10 + S --> X + S-FAT10, where X is either an E2 or E3 enzyme, the X-FAT10 linkage is a thioester bond, and the S-FAT10 linkage is an isopeptide bond between the C-terminal glycine of FAT10 and the epsilon-amino group of lysine residues in the substrate.
61662	ISG15 ligase activity	F	Catalysis of the transfer of a ISG15 to a substrate protein via the reaction X-ISG15 + S --> X + S-ISG15, where X is either an E2 or E3 enzyme, the X-ISG15 linkage is a thioester bond, and the S-ISG15 linkage is an isopeptide bond between the C-terminal amino acid of ISG15 and the epsilon-amino group of lysine residues in the substrate.
61663	NEDD8 ligase activity	F	Catalysis of the transfer of NEDD8 to a substrate protein via the reaction X-NEDD8 + S --> X + S-NEDD8, where X is either an E2 or E3 enzyme, the X-NEDD8 linkage is a thioester bond, and the S-NEDD8 linkage is an isopeptide bond between the C-terminal amino acid of NEDD8 and the epsilon-amino group of lysine residues in the substrate.
61664	Pup ligase activity	F	Catalysis of the transfer of Pup to a substrate protein via the reaction X-Pup + S --> X + S-Pup, where X is either an E2 or E3 enzyme, the X-Pup linkage is a thioester bond, and the S-Pup linkage is an isopeptide bond between the C-terminal amino acid of Pup and the epsilon-amino group of lysine residues in the substrate.
61665	SUMO ligase activity	F	Catalysis of the transfer of SUMO to a substrate protein via the reaction X-SUMO + S --> X + S-SUMO, where X is either an E2 or E3 enzyme, the X-SUMO linkage is a thioester bond, and the S-SUMO linkage is an isopeptide bond between the C-terminal amino acid of SUMO and the epsilon-amino group of lysine residues in the substrate.
61666	UFM1 ligase activity	F	Catalysis of the transfer of UFM1 to a substrate protein via the reaction X-UFM1 + S --> X + S-UFM1, where X is either an E2 or E3 enzyme, the X-UFM1 linkage is a thioester bond, and the S-UFM1 linkage is an isopeptide bond between the C-terminal amino acid of UFM1 and the epsilon-amino group of lysine residues in the substrate.
61667	URM1 ligase activity	F	Catalysis of the transfer of URM1 to a substrate protein via the reaction X-URM1 + S --> X + S-URM1, where X is either an E2 or E3 enzyme, the X-URM1 linkage is a thioester bond, and the S-URM1 linkage is an isopeptide bond between the C-terminal amino acid of URM1 and the epsilon-amino group of lysine residues in the substrate.
61668	mitochondrial ribosome assembly	P	The aggregation, arrangement and bonding together of the mitochondrial ribosome and of its subunits.
61669	spontaneous neurotransmitter secretion	P	Neurotransmitter secretion that occurs in the absence of the action of a secretagogue or a presynaptic action potential.
61670	evoked neurotransmitter secretion	P	Neurotransmitter secretion that occurs in the presence of the action of a secretagogue or a presynaptic action potential.
61671	Cbp3p-Cbp6 complex	C	A protein complex located at the mitochondrial ribosome tunnel exit that is involved in efficient translation and protein complex assembly.
61672	glutathione hydrolase complex	C	Enzyme complex that in S. cerevisiae has components Dug2/Dug3 and is able to catalyze the cleavage of glutathione into glutamate and Cys-Gly.
61673	mitotic spindle astral microtubule	C	Any of the mitotic spindle microtubules that radiate in all directions from the spindle poles and are thought to contribute to the forces that separate the poles and position them in relation to the rest of the cell.
61674	gap filling involved in double-strand break repair via nonhomologous end joining	P	Repair of the gaps in the DNA helix using a discontinuous template during double-strand break repair via nonhomologous end joining.
61675	RBL family protein binding	F	Interacting selectively and non-covalently with any member of the rhamnose-binding lectin (RBL) family, a family of animal lectins that show specific binding activities to L-rhamnose or D-galactose.
61676	importin-alpha family protein binding	F	Interacting selectively and non-covalently with any member of the importin-alpha family.
61677	2-dehydro-3-deoxy-D-gluconate aldolase activity	F	Catalysis of the reaction: 2-dehydro-3-deoxy-D-gluconate <=> pyruvate + D-glyceraldehyde.
61678	Entner-Doudoroff pathway	P	A cellular carbohydrate catabolic process that converts a carbohydrate to pyruvate and either glyceraldehyde or glyceraldehyde-3 phosphate by dehydration and aldol cleavage via a gluconate or 6-phosphogluconate intermediate.
61679	Entner-Doudoroff pathway through gluconate	P	The Entner-Doudoroff pathway that proceeds through a D-gluconate intermediate.
61680	Entner-Doudoroff pathway through gluconate to D-glyceraldehyde	P	The Entner-Doudoroff pathway that proceeds through a D-gluconate intermediate and yields pyruvate and D-glyceraldehyde.
61681	Entner-Doudoroff pathway through gluconate to D-glyceraldehyde-3-phosphate	P	The Entner-Doudoroff pathway that proceeds through a D-gluconate intermediate and yields pyruvate and D-glyceraldehyde-3-phosphate.
61682	seminal vesicle morphogenesis	P	The process in which the anatomical structures of a seminal vesicle are generated and organized.
61683	branching involved in seminal vesicle morphogenesis	P	The process in which the branching structure of the seminal vesicle is generated and organized. A branch is a division or offshoot from a main stem.
61684	chaperone-mediated autophagy	P	The autophagy process which begins when chaperones and co-chaperones recognize a KFERQ-related motif and unfold the substrate protein. The process ends with the catabolism of the protein in the lysosome.
61685	diphthine methylesterase activity	F	Catalysis of the reaction: diphthine methyl ester + H2O <=> diphthine + H+ + methanol.
61686	hercynylcysteine sulfoxide synthase	F	Catalysis of the reaction: L-cysteine + N-alpha,N-alpha,N-alpha-trimethyl-L-histidine + O2 <=> hercynylcysteine sulfoxide + H2O.
61687	detoxification of inorganic compound	P	Any process that reduces or removes the toxicity of inorganic compounds. These include transport of such compounds away from sensitive areas and to compartments or complexes whose purpose is sequestration of inorganic compounds.
61688	glycolytic process via Entner-Doudoroff Pathway	P	A glycolytic process in which the glucose is catabolized to pyruvate by first entering the Entner-Doudoroff pathway to yield pyruvate and glyceraldehyde-3-phosphate. The glyceraldehyde-3-phosphate is subsequently converted to pyruvate by the core glycolytic enzymes.
61689	tricellular tight junction	C	An specialized occluding junction where three epithelial cells meet. It is composed of a branching network of sealing strands that run perpendicularly to the bicellular tight junction at the point of contact between three epithelial cells in an epithelial sheet.
61690	lipoamidase activity	F	Catalysis of the cleavage of the amide bond to release lipoic acid from a lipoylated protein.
61691	detoxification of hydrogen peroxide	P	Any process that reduces or removes the toxicity of hydrogen peroxide. These include transport of hydrogen peroxide away from sensitive areas and to compartments or complexes whose purpose is sequestration.
61692	cellular detoxification of hydrogen peroxide	P	Any process that reduces or removes the toxicity of hydrogen peroxide in a cell. These include transport of hydrogen peroxide away from sensitive areas and to compartments or complexes whose purpose is sequestration.
61693	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity	F	Catalysis of the reaction: ATP + methylphosphonate = alpha-D-ribose 1-methylphosphonate 5-triphosphate + adenine.
61694	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase complex	C	A catalytic protein complex that is capable of alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity.
61695	transferase complex, transferring phosphorus-containing groups	C	A transferase complex capable of catalysis of the transfer of a phosphorus-containing group from one compound (donor) to another (acceptor).
61696	pituitary gonadotropin complex	C	A protein complex that is a protein hormone secreted by gonadotrope cells of the anterior pituitary of vertebrates. capable of regulating normal growth, sexual development, and reproductive function.
61697	protein-glutaryllysine deglutarylase activity	F	Catalysis of the reaction: protein-glutaryllysine + H2O => protein-lysine + glutarate. This reaction is the removal of a glutaryl group from a glutarylated lysine residue of a protein or peptide.
61698	protein deglutarylation	P	The removal of a glutaryl group (CO-CH2-CH2-CH2-CO) from a residue in a peptide or protein.
61699	peptidyl-lysine deglutarylation	P	The removal of a glutaryl group (CO-CH2-CH2--CH2-CO) from a glutarylated lysine residue in a peptide or protein.
61700	GATOR2 complex	C	A multiprotein subcomplex of GATOR that regulates mTOR signaling by interacting with the Rag GTPases. In humans this complex consists of Mios, WDR24, WDR59, Seh1L, Sec13.
61701	bacterial outer membrane vesicle	C	A spherical, bilayered proteolipid vesicle released from gram-negative bacterial outer membranes.
61702	inflammasome complex	C	A cytosolic protein complex that is capable of activating caspase-1.
61703	pyroptosome complex	C	A protein complex that consists of an assemble of ASC dimers that is capable of inducing pyroptosis.
61704	glycolytic process from sucrose	P	The chemical reactions and pathways resulting in the breakdown of a sucrose into pyruvate, with the concomitant production of a small amount of ATP and the reduction of NAD(P) to NAD(P)H. Glycolysis begins with the metabolism of a carbohydrate to generate products that can enter the pathway and ends with the production of pyruvate. Pyruvate may be converted to acetyl-coenzyme A, ethanol, lactate, or other small molecules.
61705	sucrose catabolic process to fructose-6-phosphate through glucose and fructose	P	The chemical reactions and pathways resulting in the breakdown of sucrose, to yield fructose-6-phosphate through both glucose and fructose intermediates.
61706	glycolytic process from sucrose through glucose and fructose	P	The chemical reactions and pathways resulting in the breakdown of sucrose into pyruvate through both glucose and fructose intermediates, with the concomitant production of a small amount of ATP and the reduction of NAD(P) to NAD(P)H. Glycolysis begins with the metabolism of a carbohydrate to generate products that can enter the pathway and ends with the production of pyruvate. Pyruvate may be converted to acetyl-coenzyme A, ethanol, lactate, or other small molecules.
61707	extracellular exosome macropinocytosis	P	The single-organism macropinocytosis process that results in the uptake of an extracellular exosome.
61708	tRNA-5-taurinomethyluridine 2-sulfurtransferase	F	Catalysis of 5-taurinomethyluridine in tRNA + a [protein]-S-sulfanylcysteine + ATP + a reduced electron acceptor = a 5-taurinomethyl-2-thiouridine in tRNA + a [protein]-L-cysteine + AMP + an oxidized electron acceptor + diphosphate + H+.
61709	reticulophagy	P	The autophagic process in which parts of the endoplasmic reticulum are loaded into autophagosomes, delivered to the vacuole, and degraded in response to changing cellular conditions.
61710	L-threonylcarbamoyladenylate synthase	F	Catalysis of the reaction: L-threonine + ATP + bicarbonate = L-threonylcarbamoyladenylate + diphosphate + H(2)O.
61711	N(6)-L-threonylcarbamoyladenine synthase	F	Catalysis of the reaction: L-threonylcarbamoyladenylate + adenine(37) in tRNA = AMP + N(6)-L-threonylcarbamoyladenine(37) in tRNA.
61712	tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase	F	Catalysis of the reaction: N(6)-L-threonylcarbamoyladenine(37) in tRNA + sulfur-(sulfur carrier) + 2 S-adenosyl-L-methionine = 2-methylthio-N(6)-L-threonylcarbamoyladenine(37) in tRNA + S-adenosyl-L-homocysteine + (sulfur carrier) + L-methionine + 5'-deoxyadenosine.
61713	anterior neural tube closure	P	The step in the formation of the neural tube, where the paired anterior neural folds are brought together and fuse at the dorsal midline.
61714	folic acid receptor activity	F	Combining selectively with extracellular folic acid and delivering it into the cell via endocytosis.
61715	miRNA 2'-O-methylation	P	The posttranscriptional addition of a methyl group to the 2' oxygen atom of a nucleotide residue in an miRNA molecule.
61716	miRNA export from nucleus	P	The directed movement of a processed miRNA from the nucleus to the cytoplasm.
61717	miRNA transporter activity	F	Enables the directed movement of cleaved miRNAs between the nucleus and the cytoplasm of a cell.
61718	glucose catabolic process to pyruvate	P	The chemical reactions and pathways resulting in the breakdown of glucose, with the production of pyruvate.
61719	glucose catabolic process to pyruvate utilizing ADP	P	The chemical reactions and pathways resulting in the breakdown of glucose into pyruvate, with the concomitant production of a small amount of ATP and the utilization of ADP in the initial kinase reactions.
61720	6-sulfoquinovose(1-) catabolic process to glycerone phosphate and 3-sulfolactaldehyde	P	The chemical reactions and pathways resulting in the breakdown of 6-sulfoquinovose(1-) resulting in the formation of glycerone phosphate (DHAP) and 3-sulfolactaldehyde (SLA).
61721	6-sulfoquinovose(1-) catabolic process to 3-sulfopropanediol(1-)	P	The chemical reactions and pathways resulting in the breakdown of 6-sulfoquinovose(1-) resulting in the formation of glycerone phosphate (DHAP) and 3-sulfopropanediol(1-).
61722	sulphoglycolysis	P	The chemical reactions and pathways resulting in the breakdown of 6-sulfoquinovose(1-) resulting in the formation of glycerone phosphate (DHAP) and pyruvate.
61723	glycophagy	P	The autophagic process in which cellular glycogen is delivered to the vacuole and degraded in response to changing cellular conditions.
61724	lipophagy	P	The autophagic process in which lipid droplets are delivered to the vacuole and degraded in response to changing cellular conditions.
61725	cytosolic lipolysis	P	The chemical reactions and pathways resulting in the breakdown of lipid droplets and hydrolysis of stored triglycerides occurring through the orchestrated activation of cytosolic lipases.
61726	mitochondrion disassembly	P	The disaggregation of a mitochondrion into its constituent components.
61727	methylglyoxal catabolic process to lactate	P	The chemical reactions and pathways resulting in the breakdown of methylglyoxal, CH3-CO-CHO, into lactate.
61728	GDP-mannose biosynthetic process from mannose	P	The chemical reactions and pathways resulting in the formation of GDP-mannose from mannose.
61729	GDP-mannose biosynthetic process from fructose-6-phosphate	P	The chemical reactions and pathways resulting in the formation of GDP-mannose from fructose-6-phosphate.
61730	C-rich strand telomeric DNA binding	F	Interacting selectively and non-covalently with C-rich, single-stranded, telomere-associated DNA.
61731	ribonucleoside-diphosphate reductase activity	F	Catalysis of the formation of 2'-deoxyribonucleoside diphosphate from ribonucleoside diphosphate, using either thioredoxin disulfide or glutaredoxin disulfide as an acceptor.
61732	mitochondrial acetyl-CoA biosynthetic process from pyruvate	P	The chemical reactions and pathways resulting in the formation of acetyl-CoA from pyruvate in the mitochondrion. The process begins with the transport of pyruvate from the cytosol to the mitochondrion where it is subsequently decarboxylated to form acetyl-CoA.
61733	peptide-lysine-N-acetyltransferase activity	F	Catalysis of the reaction: acetyl-CoA + lysine in peptide = CoA + N-acetyl-lysine-peptide.
61734	parkin-mediated mitophagy in response to mitochondrial depolarization	P	The macromitophagy pathway that is triggered by mitochondrial depolarization and requires the function of a parkin-family molecule.
61735	dynamin-like protein-mediated mitophagy in response to mitochondrial depolarization	P	The macromitophagy pathway that is triggered by mitochondrial depolarization and requires the function of a dynamin-like molecule.
61736	engulfment of target by autophagosome	P	The membrane invagination process by which an autophagosomal membrane surrounds an object that will be degraded by macroautophagy.
61737	leukotriene signaling pathway	P	A series of molecular signals that proceeds with an activated receptor promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. The GTP-bound activated alpha-G-protein then dissociates from the beta- and gamma-subunits to further transmit the signal within the cell. The pathway begins with receptor-leukotriene interaction and ends with regulation of a downstream cellular process, e.g. transcription.
61738	late endosomal microautophagy	P	The autophagy process by which cytosolic proteins targeted for degradation are tagged with a chaperone and are directly transferred into and degraded in a late endosomal compartment.
61739	protein lipidation involved in autophagosome assembly	P	The protein lipidation process by which phosphatidylethanolamine is conjugated to a protein of the ATG8 family, leading to membrane insertion of the protein as a step in autophagosome assembly.
61740	protein targeting to lysosome involved in chaperone-mediated autophagy	P	The targeting of a protein to the lysosome process in which an input protein binds to a chaperone and subsequently to a lysosomal receptor.
61741	chaperone-mediated protein transport involved in chaperone-mediated autophagy	P	The chaperone-mediated protein transport process in which a protein that is bound to a chaperone and a lysosomal receptor is unfolded and transported into the lysosome as part of chaperone-mediated autophagy.
61742	chaperone-mediated autophagy translocation complex	C	A lysosomal membrane protein complex that enables the translocation of a target protein across the lysosomal membrane as part of chaperone-mediated autophagy.
61743	motor learning	P	Any process in which an organism acquires a novel neuromuscular action or movement as the result of experience.
61744	motor behavior	P	The specific neuromuscular movement of a single organism in response to external or internal stimuli.
61745	GTPase activity, coupled	F	Catalysis of the reaction: GTP + H2O = GDP + phosphate; this reaction directly drives some other reaction.
61746	single-stranded DNA-dependent GTPase activity	F	Catalysis of the reaction: GTP + H2O = GDP + phosphate; this reaction requires the presence of single-stranded DNA, and it drives another reaction.
61747	CTPase activity, coupled	F	Catalysis of the reaction: CTP + H2O = CDP + phosphate; this reaction directly drives some other reaction.
61748	single-stranded DNA-dependent CTPase activity	F	Catalysis of the reaction: CTP + H2O = CDP + phosphate; this reaction requires the presence of single-stranded DNA, and it drives another reaction.
61749	forked DNA-dependent helicase activity	F	Catalysis of the reaction: NTP + H2O = NDP + phosphate, to drive the unwinding of a DNA helix containing forked DNA.
61750	acid sphingomyelin phosphodiesterase activity	F	Catalysis of the reaction: H(2)O + sphingomyelin = ceramide + choline phosphate + H(+) in an acidic environment.
61751	neutral sphingomyelin phosphodiesterase activity	F	Catalysis of the reaction: H(2)O + sphingomyelin = ceramide + choline phosphate + H(+) in a neutral environment.
61752	telomeric repeat-containing RNA binding	F	Interacting selectively and non-covalently with long non-coding RNA molecules transcribed from subtelomeric regions in most eukaryotes. Telomeric repeat-containing RNA (TERRA) molecules consist of subtelomeric-derived sequences and G-rich telomeric repeats.
61753	substrate localization to autophagosome	P	The localization process by which an autophagic substrate is delivered to a forming autophagosome.
61754	negative regulation of circulating fibrinogen levels	P	Any process that reduces the quantity of fibrinogen circulating in the bloodstream.
61755	positive regulation of circulating fibrinogen levels	P	Any process that increases the quantity of fibrinogen circulating in the bloodstream.
61756	leukocyte adhesion to vascular endothelial cell	P	The attachment of a leukocyte to vascular endothelial cell via adhesion molecules.
61757	leukocyte adhesion to arterial endothelial cell	P	The attachment of a leukocyte to an arterial endothelial cell via adhesion molecules.
61758	2-hydroxyglutarate dehydrogenase activity, forward reaction	F	Catalysis of the reaction: (S)-2-hydroxyglutarate + acceptor -> 2-oxoglutarate + reduced acceptor.
61759	alpha-ketoglutarate reductase activity	F	Catalysis of the reaction: 2-oxoglutarate + reduced acceptor -> (S)-2-hydroxyglutarate + acceptor.
61760	antifungal innate immune response	P	An defense response against a fungus mediated through an innate immune response. An innate immune response is mediated by germline encoded components that directly recognize components of potential pathogens.
61761	alpha-latrotoxin receptor binding	F	Interacting selectively and non-covalently with an alpha-latrotoxin receptor.
61762	CAMKK-AMPK signaling cascade	P	A series of molecular signals in which calmodulin-dependent protein kinase activity enabled by a CAMKK directly activates an AMPK. The cascade begins with calmodulin binding calcium which in turn binds CAMKK enabling its calmodulin-dependent protein kinase activity. The cascade ends with AMP-activated protein kinase activity.
61763	multivesicular body-lysosome fusion	P	The organelle membrane fusion process in which the membrane of a multivesicular body fuses with a lysosome to create a hybrid organelle.
61764	late endosome to lysosome transport via multivesicular body sorting pathway	P	The directed movement of substances from late endosomes to lysosomes by a pathway in which molecules are sorted into multivesicular bodies, which then fuse with the lysosome.
61765	modulation by virus of host NIK/NF-kappaB signaling	P	Any process in which a virus effect a change in the frequency, rate or extent of NIK/NF-kappaB signaling in the host.
61766	positive regulation of lung blood pressure	P	The process that increases the force with which blood travels through the lungs.
61767	negative regulation of lung blood pressure	P	The process that decreases the force with which blood travels through the lungs.
61768	magnesium:sodium antiporter activity	F	Catalysis of the reaction: Na+(in) + Mg2+(out) = Na+(out) + Mg2+(in).
61769	ribosylnicotinate kinase activity	F	Catalysis of the reaction: N-ribosylnicotinate + ATP = ADP + 2 H(+) + nicotinate mononucleotide.
61770	translation elongation factor binding	F	Interacting selectively and non-covalently with a translation elongation factor, any polypeptide factor involved in the peptide elongation in ribosome-mediated translation.
61771	response to caloric restriction	P	A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a caloric restriction, insufficient food energy intake.
61772	drug transport across blood-nerve barrier	P	The directed movement of drugs passing through the blood-nerve barrier.
61773	eNoSc complex	C	A chromatin silencing complex that recruits histone-modifying enzymes and upregulates silencing of rDNA in response to glucose starvation.
61774	cohesin unloading	P	Negative regulation of sister chromatid cohesion by the topological unlinking of a cohesin ring to DNA.
61775	cohesin ATPase activity	F	Catalysis of the reaction: ATP + H2O = ADP + phosphate; this reaction drives the topological linking or unlinking of chromatin from a cohesin ring complex.
61776	topological DNA entrapment activity	F	The DNA binding activity by which a protein complex interacts selectively and non-covalently with more than one DNA duplex to encircle the DNA molecules with a loose fitting ring.
61777	DNA clamp activity	F	A DNA binding activity in which a protein complex interacts selectively and non-covalently with single DNA duplex to tightly encircle the DNA.
61778	intracellular chloride channel activity	F	Enables the transmembrane transfer of chloride across the membrane of an intracellular compartment. Transport by a channel involves catalysis of facilitated diffusion of a solute (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel, without evidence for a carrier-mediated mechanism.
61779	Tapasin-ERp57 complex	C	Subunit of the MHC class I peptide loading complex (GO:0042824) (=PLC) involved in the assembly of the heavy-chain-beta2-microglobulin dimers of the MHC class I molecules that fold with eight to ten residue peptides in the endoplasmic reticulum. Required for the inhibition of the reduction of the disulfide bonds of the heavy chains and the assembly and stabilization of the PLC, suggesting it may play a structural rather than a catalytic role.
61780	mitotic cohesin loading	P	The protein localization to chromatin by which a cohesin ring complex is topologically linked to DNA as part of the mitotic cell cycle.
61781	mitotic cohesin unloading	P	Negative regulation of sister chromatid cohesion by the topological unlinking of a cohesin ring to DNA as part of the mitotic cell cycle.
61782	vesicle fusion with vesicle	P	Fusion of the membrane of a transport vesicle with a target membrane on another vesicle.
61783	peptidoglycan muralytic activity	F	A catalytic activity that contributes to the degradation of peptidoglycan.
61784	peptidoglycan N-acetylglucosaminidase activity	F	Catalysis of the hydrolysis of (1->4)-beta linkages of N-acetyl-D-glucosamine (GlcNAc) from peptidoglycan.
61785	peptidoglycan endopeptidase activity	F	An endopeptidase activity that uses peptidoglycan as a substrate.
61786	peptidoglycan stem peptide endopeptidase activity	F	A peptidoglycan endopeptidase activity that acts on a stem peptide of peptidoglycan.
61787	peptidoglycan cross-bridge peptide endopeptidase activity	F	A peptidoglycan endopeptidase activity that acts on a peptidoglycan cross-bridge.
61788	EGF repeat binding	F	Interacting selectively and non-covalently with Epidermal Growth Factor (EGF) repeats.
61789	dense core granule priming	P	A process that converts unprimed dense core granules (DCVs) to a pool of primed vesicles that are capable of fusing with the plasma membrane (fusion-competent) and thereby releasing their contents. Priming typically occurs after docking.
61790	dense core granule docking	P	The initial attachment of a dense core granule membrane to the plasma membrane.
61791	GTPase motor activity	F	Catalysis of the generation of force resulting either in movement along a microfilament or microtubule, or in torque resulting in membrane scission, coupled to the hydrolysis of GTP.
61792	secretory granule maturation	P	Steps required to transform an immature secretory vesicle into a mature secretory vesicle. Typically proceeds through homotypic membrane fusion and membrane remodelling.
61793	chromatin lock complex	C	A chromatin silencing complex that binds and bridges separate nucleosomal histones resulting in heterochromatin assembly and chromatin looping.
61794	conidium development	P	The process whose specific outcome is the progression of conidium over time, from its formation to the mature structure. Conidia are non-motile spores produced via mitotic asexual reproduction in higher fungi; they are haploid cells genetically identical to their haploid parent. They are produced by conversion of hyphal elements, or are borne on sporogenous cells on or within specialized structures termed conidiophores, and participate in dispersal of the fungus.
61795	Golgi lumen acidification	P	Any process that reduces the pH of the Golgi lumen, measured by the concentration of the hydrogen ion.
61796	membrane addition at site of mitotic cytokinesis	P	A mitotic cell cycle process involved in the net addition of membrane at the site of cytokinesis; includes vesicle recruitment and fusion, local lipid synthesis and insertion.
61797	pH-gated chloride channel activity	F	A gated channel activity that enables the transmembrane transfer of a chloride ion by a channel that opens in response to a change in pH.
61798	GTP 3',8'-cyclase activity	F	Catalysis of the reaction: GTP=(8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.
61799	cyclic pyranopterin monophosphate synthase activity	F	Catalysis of the reaction: (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate = cyclic pyranopterin phosphate + diphosphate.
61800	fibronectin fibril	C	A supramolecular fiber formed from fibronectin molecules. The fibrils are 5 to 25nm in diameter and can form branched meshworks.
61801	laminin-5B complex	C	A laminin complex composed of alpha3B, beta3 and gamma2 polypeptide chains.
61802	anterior cell cortex	C	The region that lies just beneath the plasma membrane in the part of a cell that is closest to the anterior as defined by the developing, or existing, anterior/posterior axis.
61803	posterior cell cortex	C	The region that lies just beneath the plasma membrane in the part of a cell that is closest to the posterior as defined by the developing, or existing, anterior/posterior axis.
61804	mitotic spindle elongation during mitotic prophase	P	The cell cycle process in which the distance is lengthened between poles of the mitotic spindle during mitotic prophase.
61805	mitotic spindle elongation during mitotic anaphase	P	The cell cycle process in which the distance is lengthened between poles of the mitotic spindle during mitotic anaphase B.
61806	regulation of DNA recombination at centromere	P	Any process that modulates the frequency, rate or extent of DNA recombination within centromeric DNA.
61807	positive regulation of DNA recombination at centromere	P	Any process that activates or increases the frequency, rate or extent of DNA recombination at the centromere.
61808	negative regulation of DNA recombination at centromere	P	Any process that stops, prevents, or reduces the frequency, rate or extent of genetic recombination at the centromere.
61809	NAD+ nucleotidase, cyclic ADP-ribose generating	F	Catalysis of the reaction: NAD+ + H2O = nicotinamide + ADP-ribose that proceeds in a stepwise fashion by ADP-ribosyl cyclase activity followed by cyclic ADP-ribose hydrolase activity.
61810	NAD glycohydrolase activity	F	Catalysis of the reaction: NAD+ + H2O = nicotinamide + ADP-ribose without proceeding through a cyclic ADP-ribose intermediate.
61811	ADP-ribosyl cyclase activity	F	Catalysis of the reaction: NAD = cyclic ADP-ribose + nicotinamide.
61812	cyclic ADP-ribose hydrolase	F	Catalysis of the reaction: cyclic ADP-ribose + H20 = ADP-ribose (ADPR).
61814	condensin I complex	C	A condensin complex that associates with chromosomes after nuclear envelope breakdown.
61815	ubiquitinyl hydrolase activity, acting on linear ubiquitin	F	Catalysis of the hydrolysis of ubiquitin units from linear ubiquitin chains.
61816	proteaphagy	P	The macroautophagy process that clears 26S proteasomes; homeostatic mechanism within the ubiquitin system that modulates proteolytic capacity and eliminates damaged particles.
61817	endoplasmic reticulum-plasma membrane tethering	P	The attachment of a the endoplasmic reticulum to the plasma membrane.
61818	tRNA folding	P	The process of assisting in the folding of tRNAs into the correct tertiary structure.
61819	telomeric DNA-containing double minutes formation	P	A telomere maintenance process that results in the formation of small fragments of circular extrachromosomal DNA elements which contain telomeric DNA. It is speculated that telomeric DNA-containing double minutes are formed through a recombination event between the telomere and chromosome-internal TTAGGG-like sequences. Telomeric DNA-containing double minutes appear as two closely positioned dots in metaphase.
61820	telomeric D-loop disassembly	P	A telomere loop disassembly process that results in the disassembly of telomeric D-loops. A telomeric D-loop is a three-stranded DNA displacement loop that forms at the site where the telomeric 3' single-stranded DNA overhang (formed of the repeat sequence TTAGGG in mammals) is tucked back inside the double-stranded component of telomeric DNA molecule, thus forming a t-loop or telomeric-loop and protecting the chromosome terminus.
61821	telomeric D-loop binding	F	Interacting selectively and non-covalently with a telomeric D-loop. A telomeric D-loop is a three-stranded DNA displacement loop that forms at the site where the telomeric 3' single-stranded DNA overhang (formed of the repeat sequence TTAGGG in mammals) is tucked back inside the double-stranded component of telomeric DNA molecule, thus forming a t-loop or telomeric-loop and protecting the chromosome terminus.
65001	specification of axis polarity	P	The pattern specification process in which the polarity of a body or organ axis is established and maintained.
65002	intracellular protein transmembrane transport	P	The directed movement of proteins in a cell, from one side of a membrane to another by means of some agent such as a transporter or pore.
65003	macromolecular complex assembly	P	The aggregation, arrangement and bonding together of a set of macromolecules to form a complex.
65004	protein-DNA complex assembly	P	The aggregation, arrangement and bonding together of proteins and DNA molecules to form a protein-DNA complex.
65005	protein-lipid complex assembly	P	The aggregation, arrangement and bonding together of proteins and lipids to form a protein-lipid complex.
65006	protein-carbohydrate complex assembly	P	The aggregation, arrangement and bonding together of proteins and carbohydrates to form a protein-carbohydrate complex.
65007	biological regulation	P	Any process that modulates a measurable attribute of any biological process, quality or function.
65008	regulation of biological quality	P	Any process that modulates a qualitative or quantitative trait of a biological quality. A biological quality is a measurable attribute of an organism or part of an organism, such as size, mass, shape, color, etc.
65009	regulation of molecular function	P	Any process that modulates the frequency, rate or extent of a molecular function, an elemental biological activity occurring at the molecular level, such as catalysis or binding.
65010	extracellular membrane-bounded organelle	C	Organized structure of distinctive morphology and function, bounded by a lipid bilayer membrane and occurring outside the cell.
70001	aspartic-type peptidase activity	F	Catalysis of the hydrolysis of peptide bonds in a polypeptide chain by a mechanism in which a water molecule bound by the side chains of aspartic residues at the active center acts as a nucleophile.
70002	glutamic-type peptidase activity	F	Catalysis of the hydrolysis of peptide bonds in a polypeptide chain by a mechanism involving a glutamate/glutamine catalytic dyad.
70003	threonine-type peptidase activity	F	Catalysis of the hydrolysis of peptide bonds in a polypeptide chain by a mechanism in which the hydroxyl group of a threonine residue at the active center acts as a nucleophile.
70004	cysteine-type exopeptidase activity	F	Catalysis of the hydrolysis of C- or N-terminal peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile.
70005	cysteine-type aminopeptidase activity	F	Catalysis of the hydrolysis of N-terminal peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile.
70006	metalloaminopeptidase activity	F	Catalysis of the hydrolysis of N-terminal amino acid residues from a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions.
70007	glutamic-type endopeptidase activity	F	Catalysis of the hydrolysis of internal peptide bonds in a polypeptide chain by a mechanism involving a glutamate/glutamine catalytic dyad.
70008	serine-type exopeptidase activity	F	Catalysis of the hydrolysis of a peptide bond not more than three residues from the N- or C-terminus of a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine).
70009	serine-type aminopeptidase activity	F	Catalysis of the hydrolysis of a peptide bond not more than three residues from the N-terminus of a polypeptide chain by a catalytic mechanism that involves a catalytic triad consisting of a serine nucleophile that is activated by a proton relay involving an acidic residue (e.g. aspartate or glutamate) and a basic residue (usually histidine).
70010	peptidase activity, acting on D-amino acid peptides	F	Catalysis of the hydrolysis of peptide bonds formed between D-amino acids.
70011	peptidase activity, acting on L-amino acid peptides	F	Catalysis of the hydrolysis of peptide bonds formed between L-amino acids.
70012	oligopeptidase activity	F	Catalysis of the hydrolysis of a peptide bond in an oligopeptide, i.e. a molecule containing a small number (2 to 20) of amino acid residues connected by peptide bonds.
70013	intracellular organelle lumen	C	An organelle lumen that is part of an intracellular organelle.
70014	sucrase-isomaltase complex	C	A protein complex that possesses oligo-1,6-glucosidase activity; the complex is a heterodimer located in the cell membrane, and is formed by proteolytic cleavage of a single precursor polypeptide. The two subunits have different substrate specificities.
70016	armadillo repeat domain binding	F	Interacting selectively and non-covalently with the armadillo repeat domain of a protein, an approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity protein armadillo. Arm-repeat proteins are involved in various processes, including intracellular signalling and cytoskeletal regulation.
70017	alphav-beta3 integrin-thrombospondin complex	C	A protein complex that consists of an alphav-beta3 integrin complex bound to thrombospondin.
70018	transforming growth factor beta type I receptor homodimeric complex	C	A receptor complex that consists of two transforming growth factor beta (TGF-beta) type I receptor monomers. TGF-beta type I receptor dimers form in the presence or absence of ligand, and can associate with ligand-bound TGF-beta type II receptor dimers.
70019	transforming growth factor beta type II receptor homodimeric complex	C	A receptor complex that consists of two transforming growth factor beta (TGF-beta) type II receptor monomers. TGF-beta type II receptor dimers form in the presence or absence of ligand, and upon ligand binding can associate with TGF-beta type I receptor dimers.
70020	transforming growth factor beta1-type II receptor complex	C	A protein complex that consists of a dimeric transforming growth factor beta (TGF-beta) type II receptor bound to a TGF-beta1 dimer.
70021	transforming growth factor beta1-type II receptor-type I receptor complex	C	A protein complex that is formed by the association of a ligand-bound TGF-beta type II receptor dimer with a TGF-beta type I receptor dimer.
70022	transforming growth factor beta receptor complex	C	A homodimeric receptor complex that consists of two TGF-beta receptor monomers.
70023	interleukin-12-interleukin-12 receptor complex	C	A protein complex that is formed by the association of a heterodimeric interleukin-12 receptor complex with an interleukin-12 heterodimer.
70024	CD19-Vav-PIK3R1 complex	C	A protein complex that contains the cell surface signaling molecule CD19, the Ras guanine nucleotide exchange factor Vav, and the regulatory subunit alpha of phosphatidylinositol 3-kinase (PI3K).
70025	carbon monoxide binding	F	Interacting selectively and non-covalently with carbon monoxide (CO).
70026	nitric oxide binding	F	Interacting selectively and non-covalently with nitric oxide (NO).
70027	carbon monoxide sensor activity	F	Interacting selectively and non-covalently with and responding, e.g. by conformational change, to changes in the cellular level of carbon monoxide (CO).
70028	regulation of transcription by carbon monoxide	P	Any process involving carbon monoxide that modulates the frequency, rate or extent of transcription.
70029	alphav-beta3 integrin-osteopontin complex	C	A protein complex that consists of an alphav-beta3 integrin complex bound to osteopontin.
70030	alphav-beta1 integrin-osteopontin complex	C	A protein complex that consists of an alphav-beta1 integrin complex bound to osteopontin.
70031	alphav-beta5 integrin-osteopontin complex	C	A protein complex that consists of an alphav-beta5 integrin complex bound to osteopontin.
70032	synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex	C	A SNARE complex that contains synaptobrevin 2 (VAMP2), SNAP-25, syntaxin 1a, and complexin I (or orthologs thereof).
70033	synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex	C	A SNARE complex that contains synaptobrevin 2 (VAMP2), SNAP-25, syntaxin 1a, and complexin II (or orthologs thereof).
70034	telomerase RNA binding	F	Interacting selectively and non-covalently with the telomerase RNA template.
70035	purine NTP-dependent helicase activity	F	Catalysis of the reaction: purine NTP + H2O = purine NDP + phosphate, to drive the unwinding of a DNA or RNA helix.
70036	GTP-dependent helicase activity	F	Catalysis of the reaction: GTP + H2O = GDP + phosphate, to drive the unwinding of a DNA or RNA helix.
70037	rRNA (pseudouridine) methyltransferase activity	F	Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a pseudouridine residue in an rRNA molecule.
70038	rRNA (pseudouridine-N3-)-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing N3-methylpseudouridine.
70039	rRNA (guanosine-2'-O-)-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing 2'-O-methylguanosine.
70040	rRNA (adenine-C2-)-methyltransferase activity	F	Catalysis of the reaction: 2 S-adenosyl-L-methionine + adenine(2503) in 23S rRNA = S-adenosyl-L-homocysteine + 5'-deoxyadenosine + L-methionine + rRNA containing C2-methyladenine(2503) in 23S rRNA.
70041	rRNA (uridine-C5-)-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing C5-methyluridine.
70042	rRNA (uridine-N3-)-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing N3-methyluridine.
70043	rRNA (guanine-N7-)-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing N7-methylguanine.
70044	synaptobrevin 2-SNAP-25-syntaxin-1a complex	C	A SNARE complex that contains synaptobrevin 2 (VAMP2), SNAP-25, and syntaxin 1a (or orthologs thereof).
70045	synaptobrevin 2-SNAP-25-syntaxin-2 complex	C	A SNARE complex that contains synaptobrevin 2 (VAMP2), SNAP-25, and syntaxin 2 (or orthologs thereof).
70046	synaptobrevin 2-SNAP-25-syntaxin-3 complex	C	A SNARE complex that contains synaptobrevin 2 (VAMP2), SNAP-25, and syntaxin 3 (or orthologs thereof).
70047	synaptobrevin 2-SNAP-25-syntaxin-4 complex	C	A SNARE complex that contains synaptobrevin 2 (VAMP2), SNAP-25, and syntaxin 4 (or orthologs thereof).
70048	endobrevin-SNAP-25-syntaxin-1a complex	C	A SNARE complex that contains endobrevin (VAMP8), SNAP-25, and syntaxin 1a (or orthologs thereof).
70049	endobrevin-SNAP-25-syntaxin-2 complex	C	A SNARE complex that contains endobrevin (VAMP8), SNAP-25, and syntaxin 2 (or orthologs thereof).
70050	neuron cellular homeostasis	P	The cellular homeostatic process that preserves a neuron in a stable, differentiated functional and structural state.
70051	fibrinogen binding	F	Interacting selectively and non-covalently with fibrinogen, a highly soluble hexameric glycoprotein complex that is found in blood plasma and is converted to fibrin by thrombin in the coagulation cascade.
70052	collagen V binding	F	Interacting selectively and non-covalently with a type V collagen trimer.
70053	thrombospondin receptor activity	F	Combining with thrombospondin and transmitting the signal to initiate a change in cell activity.
70054	mRNA splicing, via endonucleolytic cleavage and ligation	P	Splicing of mRNA substrates via recognition of the folded RNA structure that brings the 5' and 3' splice sites into proximity and cleavage of the RNA at both the 3' and 5' splice sites by an endonucleolytic mechanism, followed by ligation of the exons.
70055	mRNA endonucleolytic cleavage involved in unfolded protein response	P	The endonucleolytic cleavage of a mRNA containing an HAC1-type intron at the 5' and 3' splice sites. The cleavage step is part of unconventional mRNA splicing, and contributes to the endoplasmic reticulum unfolded protein response.
70056	prospore membrane leading edge	C	The region of the prospore membrane that extends to surround the spore nucleus; coated with specific proteins that are thought to play a role in prospore membrane organization.
70057	prospore membrane spindle pole body attachment site	C	The region of the prospore membrane to which the spindle pole body (SPB) is anchored; the prospore membrane extends from the SPB attachment site to surround the spore nucleus.
70058	tRNA gene clustering	P	The process in which tRNA genes, which are not linearly connected on the chromosome, are transported in three dimensions to, and maintained together in, the nucleolus. This clustered positioning leads to transcriptional silencing of nearby RNA polymerase II promoters (termed tRNA gene mediated (tgm) silencing) in S. cerevisiae.
70059	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress	P	A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced in response to a stimulus indicating endoplasmic reticulum (ER) stress, and ends when the execution phase of apoptosis is triggered. ER stress usually results from the accumulation of unfolded or misfolded proteins in the ER lumen.
70060	'de novo' actin filament nucleation	P	The actin nucleation process in which actin monomers combine in the absence of any existing actin filaments; elongation of the actin oligomer formed by nucleation leads to the formation of an unbranched filament.
70061	fructose binding	F	Interacting selectively and non-covalently with the D- or L-enantiomer of fructose, the ketohexose arabino-hex-2-ulose.
70062	extracellular exosome	C	A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
70063	RNA polymerase binding	F	Interacting selectively and non-covalently with an RNA polymerase molecule or complex.
70064	proline-rich region binding	F	Interacting selectively and non-covalently with a proline-rich region, i.e. a region that contains a high proportion of proline residues, in a protein.
70065	cellubrevin-VAMP4-syntaxin-16 complex	C	A SNARE complex that contains cellubrevin (VAMP3), VAMP4, and syntaxin 16 (or orthologs thereof).
70066	cellubrevin-VAMP4-endobrevin-syntaxin-6 complex	C	A SNARE complex that contains cellubrevin (VAMP3), VAMP4, endobrevin (VAMP8), and syntaxin 6 (or orthologs thereof).
70067	syntaxin-6-syntaxin-16-Vti1a complex	C	A SNARE complex that contains syntaxin 6, syntaxin 16, and Vti1a (or orthologs thereof).
70068	VAMP4-syntaxin-6-syntaxin-16-Vti1a complex	C	A SNARE complex that contains VAMP4, syntaxin 6, syntaxin 16, and Vti1a (or orthologs thereof).
70069	cytochrome complex	C	A protein complex in which at least one of the proteins is a cytochrome, i.e. a heme-containing protein involved in catalysis of redox reactions.
70070	proton-transporting V-type ATPase complex assembly	P	The aggregation, arrangement and bonding together of a proton-transporting V-type ATPase complex, proton-transporting two-sector ATPase complex that couples ATP hydrolysis to the transport of protons across a concentration gradient.
70071	proton-transporting two-sector ATPase complex assembly	P	The aggregation, arrangement and bonding together of a proton-transporting two-sector ATPase complex, a large protein complex that catalyzes the synthesis or hydrolysis of ATP by a rotational mechanism, coupled to the transport of protons across a membrane.
70072	vacuolar proton-transporting V-type ATPase complex assembly	P	The aggregation, arrangement and bonding together of a vacuolar proton-transporting V-type ATPase complex, proton-transporting two-sector ATPase complex that couples ATP hydrolysis to the transport of protons across the vacuolar membrane.
70073	clustering of voltage-gated calcium channels	P	The process in which voltage-gated calcium channels become localized together in high densities.
70074	mononeme	C	A secretory organelle that forms part of the apical complex; a small, threadlike structure located is close proximity to the subpellicular microtubules. Its contents include a rhomboid protease (PfROM1 in Plasmodium falciparum) that moves from the lateral asymmetric localization to the merozoite apical pole and the posterior pole upon release of merozoites from schizonts.
70075	tear secretion	P	The regulated release of the aqueous layer of the tear film from the lacrimal glands. Tears are the liquid product of a process of lacrimation to clean and lubricate the eyes. Tear fluid contains water, mucin, lipids, lysozyme, lactoferrin, lipocalin, lacritin, immunoglobulins, glucose, urea, sodium, and potassium.
70076	histone lysine demethylation	P	The modification of a histone by the removal of a methyl group from a lysine residue.
70077	histone arginine demethylation	P	The modification of a histone by the removal of a methyl group from an arginine residue.
70078	histone H3-R2 demethylation	P	The modification of histone H3 by the removal of a methyl group from arginine at position 2 of the histone.
70079	histone H4-R3 demethylation	P	The modification of histone H4 by the removal of a methyl group from arginine at position 3 of the histone.
70080	titin Z domain binding	F	Interacting selectively and non-covalently with the titin Z domain, which recognizes and binds to the C-terminal calmodulin-like domain of alpha-actinin-2 (Act-EF34), adopts a helical structure, and binds in a groove formed by the two planes between the helix pairs of Act-EF34.
70081	clathrin-sculpted monoamine transport vesicle	C	A clathrin-sculpted lipid bilayer membrane-enclosed vesicle after clathrin release and containing monoamines.
70082	clathrin-sculpted monoamine transport vesicle lumen	C	The volume enclosed by the membrane of the clathrin-sculpted monoamine transport vesicle.
70083	clathrin-sculpted monoamine transport vesicle membrane	C	The lipid bilayer surrounding a clathrin-sculpted monoamine transport vesicle.
70084	protein initiator methionine removal	P	The protein modification process in which the translation-initiating methionine or formylmethionine residue is removed from a protein.
70085	glycosylation	P	The covalent attachment and further modification of carbohydrate residues to a substrate molecule.
70086	ubiquitin-dependent endocytosis	P	Endocytosis of a protein that requires the substrate to be modified by ubiquitination. Several plasma membrane proteins, including cell surface permeases and some receptors, are targeted for internalization by endocytosis, and are thereafter delivered to the vacuole or lysosome, where they are degraded.
70087	chromo shadow domain binding	F	Interacting selectively and non-covalently with a chromo shadow domain, a protein domain that is distantly related, and found in association with, the chromo domain.
70088	PHA granule	C	An inclusion body located in the cytoplasm that consists of polyhydroxyalkanoate (PHA) molecules and associated proteins, surrounded by a phospholipid monolayer; the proteins include PHA synthase, PHA depolymerase and 3HB-oligomer hydroxylase, phasins (PhaPs), which are thought to be the major structural proteins of the membrane surrounding the inclusion, and the regulator of phasin expression PhaR.
70089	chloride-activated potassium channel activity	F	Enables the chloride concentration-regulatable energy-independent passage of potassium ions across a lipid bilayer down a concentration gradient.
70090	metaphase plate	C	The intracellular plane, located halfway between the poles of the spindle, where chromosomes align during metaphase of mitotic or meiotic nuclear division.
70091	glucagon secretion	P	The regulated release of glucagon from secretory granules in the A (alpha) cells of the pancreas (islets of Langerhans).
70092	regulation of glucagon secretion	P	Any process that modulates the frequency, rate or extent of the regulated release of glucagon.
70093	negative regulation of glucagon secretion	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of glucagon.
70094	positive regulation of glucagon secretion	P	Any process that activates or increases the frequency, rate or extent of the regulated release of glucagon.
70095	fructose-6-phosphate binding	F	Interacting selectively and non-covalently with fructose 6-phosphate.
70096	mitochondrial outer membrane translocase complex assembly	P	The aggregation, arrangement and bonding together of a set of components to form a mitochondrial outer membrane translocase complex.
70097	delta-catenin binding	F	Interacting selectively and non-covalently with the delta subunit of the catenin complex.
70098	chemokine-mediated signaling pathway	P	A series of molecular signals initiated by the binding of a chemokine to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.
70099	regulation of chemokine-mediated signaling pathway	P	Any process that modulates the rate, frequency or extent of the series of molecular events generated as a consequence of a chemokine binding to a cell surface receptor.
70100	negative regulation of chemokine-mediated signaling pathway	P	Any process that decreases the rate, frequency or extent of the series of molecular events generated as a consequence of a chemokine binding to a cell surface receptor.
70101	positive regulation of chemokine-mediated signaling pathway	P	Any process that increases the rate, frequency or extent of the series of molecular events generated as a consequence of a chemokine binding to a cell surface receptor.
70102	interleukin-6-mediated signaling pathway	P	A series of molecular signals initiated by the binding of interleukin-6 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.
70103	regulation of interleukin-6-mediated signaling pathway	P	Any process that modulates the rate, frequency or extent of the series of molecular events generated as a consequence of interleukin-6-mediated binding to a cell surface receptor.
70104	negative regulation of interleukin-6-mediated signaling pathway	P	Any process that decreases the rate, frequency or extent of the series of molecular events generated as a consequence of interleukin-6 binding to a cell surface receptor.
70105	positive regulation of interleukin-6-mediated signaling pathway	P	Any process that increases the rate, frequency or extent of the series of molecular events generated as a consequence of interleukin-6 binding to a cell surface receptor.
70106	interleukin-27-mediated signaling pathway	P	A series of molecular signals initiated by the binding of interleukin-27 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.
70107	regulation of interleukin-27-mediated signaling pathway	P	Any process that modulates the rate, frequency or extent of the series of molecular events generated as a consequence of interleukin-27-mediated binding to a cell surface receptor.
70108	negative regulation of interleukin-27-mediated signaling pathway	P	Any process that decreases the rate, frequency or extent of the series of molecular events generated as a consequence of interleukin-27 binding to a cell surface receptor.
70109	positive regulation of interleukin-27-mediated signaling pathway	P	Any process that increases the rate, frequency or extent of the series of molecular events generated as a consequence of interleukin-27 binding to a cell surface receptor.
70110	ciliary neurotrophic factor receptor complex	C	A protein complex that acts as a receptor for the cytokine ciliary neurotrophic factor (CNTF). In humans the receptor complex is a hexamer composed of two molecules each of CNTF and CNTFR and one molecule each of gp130 and LIFR.
70111	organellar chromatophore	C	A bacteroid-containing symbiosome in which the bacterial component is a genetically highly reduced cyanobacterium that is photosynthetically active and incapable of an independent existence outside its host. The chromatophore functions as a photosynthetic organelle, and has been found and characterized in the amoeba Paulinella chromatophora.
70112	organellar chromatophore membrane	C	Either of the lipid bilayers that surround an organellar chromatophore.
70113	organellar chromatophore inner membrane	C	The inner, i.e. lumen-facing, of the two lipid bilayers surrounding an organellar chromatophore.
70114	organellar chromatophore outer membrane	C	The outer, i.e. cytoplasm-facing, of the two lipid bilayers surrounding an organellar chromatophore.
70115	organellar chromatophore intermembrane space	C	The region between the inner and outer lipid bilayers that surround an organellar chromatophore.
70116	organellar chromatophore thylakoid	C	A thylakoid located in an organellar chromatophore.
70117	organellar chromatophore thylakoid lumen	C	The volume enclosed by an organellar chromatophore thylakoid membrane.
70118	organellar chromatophore thylakoid membrane	C	The lipid bilayer membrane of any thylakoid within an organellar chromatophore.
70119	ciliary neurotrophic factor binding	F	Interacting selectively and non-covalently with the cytokine ciliary neurotrophic factor.
70120	ciliary neurotrophic factor-mediated signaling pathway	P	A series of molecular signals initiated by the binding of a ciliary neurotrophic factor (CNTF) to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.
70121	Kupffer's vesicle development	P	The progression of the Kupffer's vesicle over time from its initial formation until its mature state. The Kupffer's vesicle is a small but distinctive epithelial sac containing fluid, located midventrally posterior to the yolk cell or its extension, and transiently present during most of the segmentation period.
70122	isopeptidase activity	F	Catalysis of the hydrolysis of an isopeptide bond. An isopeptide bond is an amide linkage between a carboxyl group of one amino acid and an amino group of another amino acid in which at least one of these groups is not on the a-carbon of one of the amino acids (for example, the link between an epsilon-amino group of a lysine molecule to a carboxyl group on a second amino acid is an isopeptide bond).
70123	transforming growth factor beta receptor activity, type III	F	Combining with transforming growth factor beta to initiate a change in cell activity; facilitates ligand binding to type I and type II TGF-beta receptors.
70124	mitochondrial translational initiation	P	The process preceding formation of the peptide bond between the first two amino acids of a protein in a mitochondrion. This includes the formation of a complex of the ribosome, mRNA, and an initiation complex that contains the first aminoacyl-tRNA.
70125	mitochondrial translational elongation	P	The successive addition of amino acid residues to a nascent polypeptide chain during protein biosynthesis in a mitochondrion.
70126	mitochondrial translational termination	P	The process resulting in the release of a polypeptide chain from the ribosome in a mitochondrion, usually in response to a termination codon (note that mitochondria use variants of the universal genetic code that differ between different taxa).
70127	tRNA aminoacylation for mitochondrial protein translation	P	The synthesis of aminoacyl tRNA by the formation of an ester bond between the 3'-hydroxyl group of the most 3' adenosine of the tRNA, to be used in ribosome-mediated polypeptide synthesis in a mitochondrion.
70129	regulation of mitochondrial translation	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA in a mitochondrion.
70130	negative regulation of mitochondrial translation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA in a mitochondrion.
70131	positive regulation of mitochondrial translation	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA in a mitochondrion.
70132	regulation of mitochondrial translational initiation	P	Any process that modulates the frequency, rate or extent of the process preceding formation of the peptide bond between the first two amino acids of a protein in a mitochondrion.
70133	negative regulation of mitochondrial translational initiation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the process preceding formation of the peptide bond between the first two amino acids of a protein in a mitochondrion.
70134	positive regulation of mitochondrial translational initiation	P	Any process that activates or increases the frequency, rate or extent of the process preceding formation of the peptide bond between the first two amino acids of a protein in a mitochondrion.
70135	beta-1,2-oligomannoside metabolic process	P	The chemical reactions and pathways involving beta-1,2-linked oligomannosides, which are found in fungal cell wall phosphopeptidomannan and phospholipomannan.
70136	beta-1,2-oligomannoside biosynthetic process	P	The chemical reactions and pathways resulting in the formation of beta-1,2-linked oligomannosides, which are found in fungal cell wall phosphopeptidomannan and phospholipomannan.
70137	ubiquitin-like protein-specific endopeptidase activity	F	Catalysis of the hydrolysis of peptide bonds between an alpha-carboxyl group and an alpha-amino group within a small protein such as ubiquitin or a ubiquitin-like protein (e.g. APG8, ISG15, NEDD8, SUMO).
70138	ubiquitin-like protein-specific isopeptidase activity	F	Catalysis of the hydrolysis of an isopeptide bond between a small protein such as ubiquitin or a ubiquitin-like protein (e.g. APG8, ISG15, NEDD8, SUMO) and a protein to which the small protein has been conjugated.
70139	SUMO-specific endopeptidase activity	F	Catalysis of the hydrolysis of peptide bonds between an alpha-carboxyl group and an alpha-amino group within the small conjugating protein SUMO.
70140	SUMO-specific isopeptidase activity	F	Catalysis of the hydrolysis of an isopeptide bond between the small conjugating protein SUMO and a protein to which SUMO has been conjugated.
70141	response to UV-A	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a UV-A radiation stimulus. UV-A radiation (UV-A light) spans the wavelengths 315 to 400 nm.
70142	synaptic vesicle budding	P	Evagination of a membrane to form a synaptic vesicle.
70143	mitochondrial alanyl-tRNA aminoacylation	P	The process of coupling alanine to alanyl-tRNA in a mitochondrion, catalyzed by alanyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.
70144	mitochondrial arginyl-tRNA aminoacylation	P	The process of coupling arginine to arginyl-tRNA in a mitochondrion, catalyzed by arginyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.
70145	mitochondrial asparaginyl-tRNA aminoacylation	P	The process of coupling asparagine to asparaginyl-tRNA in a mitochondrion, catalyzed by asparaginyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.
70146	mitochondrial aspartyl-tRNA aminoacylation	P	The process of coupling aspartate to aspartyl-tRNA in a mitochondrion, catalyzed by aspartyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.
70147	mitochondrial cysteinyl-tRNA aminoacylation	P	The process of coupling cysteine to cysteinyl-tRNA in a mitochondrion, catalyzed by cysteinyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.
70148	mitochondrial glutaminyl-tRNA aminoacylation	P	The process of coupling glutamine to glutaminyl-tRNA in a mitochondrion, catalyzed by glutaminyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.
70149	mitochondrial glutamyl-tRNA aminoacylation	P	The process of coupling glutamate to glutamyl-tRNA in a mitochondrion, catalyzed by glutamyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.
70150	mitochondrial glycyl-tRNA aminoacylation	P	The process of coupling glycine to glycyl-tRNA in a mitochondrion, catalyzed by glycyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.
70151	mitochondrial histidyl-tRNA aminoacylation	P	The process of coupling histidine to histidyl-tRNA in a mitochondrion, catalyzed by histidyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.
70152	mitochondrial isoleucyl-tRNA aminoacylation	P	The process of coupling isoleucine to isoleucyl-tRNA in a mitochondrion, catalyzed by isoleucyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.
70153	mitochondrial leucyl-tRNA aminoacylation	P	The process of coupling leucine to leucyl-tRNA in a mitochondrion, catalyzed by leucyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.
70154	mitochondrial lysyl-tRNA aminoacylation	P	The process of coupling lysine to lysyl-tRNA in a mitochondrion, catalyzed by lysyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.
70155	mitochondrial methionyl-tRNA aminoacylation	P	The process of coupling methionine to methionyl-tRNA in a mitochondrion, catalyzed by methionyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.
70156	mitochondrial phenylalanyl-tRNA aminoacylation	P	The process of coupling phenylalanine to phenylalanyl-tRNA in a mitochondrion, catalyzed by phenylalanyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.
70157	mitochondrial prolyl-tRNA aminoacylation	P	The process of coupling proline to prolyl-tRNA in a mitochondrion, catalyzed by prolyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.
70158	mitochondrial seryl-tRNA aminoacylation	P	The process of coupling serine to seryl-tRNA in a mitochondrion, catalyzed by seryl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.
70159	mitochondrial threonyl-tRNA aminoacylation	P	The process of coupling threonine to threonyl-tRNA in a mitochondrion, catalyzed by threonyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.
70160	occluding junction	C	A cell-cell junction that seals cells together in an epithelium in a way that prevents even small molecules from leaking from one side of the sheet to the other.
70161	anchoring junction	C	A cell junction that mechanically attaches a cell (and its cytoskeleton) to neighboring cells or to the extracellular matrix.
70162	adiponectin secretion	P	The regulated release of adiponectin, a protein hormone, by adipose tissue.
70163	regulation of adiponectin secretion	P	Any process that modulates the frequency, rate or extent of the regulated release of adiponectin from a cell.
70164	negative regulation of adiponectin secretion	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of adiponectin from a cell.
70165	positive regulation of adiponectin secretion	P	Any process that activates or increases the frequency, rate or extent of the regulated release of adiponectin from a cell.
70166	enamel mineralization	P	The process in which calcium salts, mainly carbonated hydroxyapatite, are deposited in tooth enamel.
70167	regulation of biomineral tissue development	P	Any process that modulates the frequency, rate or extent of biomineral tissue development, the formation of hard tissues that consist mainly of inorganic compounds.
70168	negative regulation of biomineral tissue development	P	Any process that stops, prevents, or reduces the frequency, rate or extent of biomineral tissue development, the formation of hard tissues that consist mainly of inorganic compounds.
70169	positive regulation of biomineral tissue development	P	Any process that activates or increases the frequency, rate or extent of biomineral tissue development, the formation of hard tissues that consist mainly of inorganic compounds.
70170	regulation of tooth mineralization	P	Any process that modulates the frequency, rate or extent of tooth mineralization, the deposition of calcium salts in tooth structures.
70171	negative regulation of tooth mineralization	P	Any process that stops, prevents, or reduces the frequency, rate or extent of tooth mineralization, the deposition of calcium salts in tooth structures.
70172	positive regulation of tooth mineralization	P	Any process that activates or increases the frequency, rate or extent of tooth mineralization, the deposition of calcium salts in tooth structures.
70173	regulation of enamel mineralization	P	Any process that modulates the frequency, rate or extent of enamel mineralization, the deposition of calcium salts in tooth enamel.
70174	negative regulation of enamel mineralization	P	Any process that stops, prevents, or reduces the frequency, rate or extent of enamel mineralization, the deposition of calcium salts in tooth enamel.
70175	positive regulation of enamel mineralization	P	Any process that activates or increases the frequency, rate or extent of enamel mineralization, the deposition of calcium salts in tooth enamel.
70176	DRM complex	C	A transcriptional repressor complex that contains the lin-9, lin-35, lin-37, lin-52, lin-53, lin-5is involved in 4-, dpl-1 and efl-1 proteins, and is involved in cell fate specification.
70177	contractile vacuole discharge	P	The regulated release of water from a contractile vacuole to the outside of a cell by fusion of the contractile vacuole membrane with the plasma membrane.
70178	D-serine metabolic process	P	The chemical reactions and pathways involving D-serine, the D-enantiomer of serine, i.e. (2R)-2-amino-3-hydroxypropanoic acid.
70179	D-serine biosynthetic process	P	The chemical reactions and pathways resulting in the formation of D-serine, the D-enantiomer of serine, i.e. (2R)-2-amino-3-hydroxypropanoic acid. D-serine is often formed by racemization of L-serine.
70180	large ribosomal subunit rRNA binding	F	Interacting selectively and non-covalently with the large ribosomal subunit RNA (LSU rRNA), a constituent of the large ribosomal subunit. In S. cerevisiae, this is the 25S rRNA.
70181	small ribosomal subunit rRNA binding	F	Interacting selectively and non-covalently with the small ribosomal subunit RNA (SSU rRNA), a constituent of the small ribosomal subunit. In S. cerevisiae, this is the 18S rRNA.
70182	DNA polymerase binding	F	Interacting selectively and non-covalently with a DNA polymerase.
70183	mitochondrial tryptophanyl-tRNA aminoacylation	P	The process of coupling tryptophan to tryptophanyl-tRNA in a mitochondrion, catalyzed by tryptophanyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.
70184	mitochondrial tyrosyl-tRNA aminoacylation	P	The process of coupling tyrosine to tyrosyl-tRNA in a mitochondrion, catalyzed by tyrosyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.
70185	mitochondrial valyl-tRNA aminoacylation	P	The process of coupling valine to valyl-tRNA in a mitochondrion, catalyzed by valyl-tRNA synthetase. In tRNA aminoacylation, the amino acid is first activated by linkage to AMP and then transferred to either the 2'- or the 3'-hydroxyl group of the 3'-adenosine residue of the tRNA.
70186	growth hormone activity	F	The action characteristic of growth hormone, a peptide hormone that is secreted by the anterior pituitary or the placenta into the circulation, and binds to membrane receptors in target tissues to stimulate body growth.
70187	telosome	C	A nuclear telomere cap complex that is formed by the association of telomeric ssDNA- and dsDNA-binding proteins with telomeric DNA, and is involved in telomere protection and recruitment of telomerase. The complex is known to contain TERF1, TERF2, POT1, RAP1, TINF2 and ACD in mammalian cells, and Pot1, Tpz1, Rap1, Rif1, Rif2 and Taz1 in Schizosaccharomyces. Taz1 and Rap1 (or their mammalian equivalents) form a dsDNA-binding subcomplex, Pot1 and Tpz1 form an ssDNA-binding subcomplex, and the two subcomplexes are bridged by Poz1, which acts as an effector molecule along with Ccq1.
70189	kynurenine metabolic process	P	The chemical reactions and pathways involving kynurenine, the amino acid 3-(2-aminobenzoyl)-alanine.
70191	methionine-R-sulfoxide reductase activity	F	Catalysis of the reaction: L-methionine R-oxide + thioredoxin = L-methionine + thioredoxin disulfide; can act on free oxidized methionine with specificity for the R enantiomer; does not act on oxidized methionine in peptide linkage. Thioredoxin disulfide is the oxidized form of thioredoxin.
70192	chromosome organization involved in meiotic cell cycle	P	A process of chromosome organization that is involved in a meiotic cell cycle.
70193	synaptonemal complex organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a synaptonemal complex. A synaptonemal complex is a proteinaceous scaffold formed between homologous chromosomes during meiosis.
70194	synaptonemal complex disassembly	P	The controlled breakdown of a synaptonemal complex.
70195	growth hormone receptor complex	C	A receptor complex that consists of two identical subunits and binds growth hormone.
70196	eukaryotic translation initiation factor 3 complex assembly	P	The aggregation, arrangement and bonding together of a set of components to form the eukaryotic translation initiation factor 3 complex.
70197	meiotic attachment of telomere to nuclear envelope	P	The meiotic cell cycle process in which physical connections are formed between telomeric heterochromatin and the nuclear envelope, facilitating bouquet formation.
70198	protein localization to chromosome, telomeric region	P	Any process in which a protein is transported to, or maintained at, the telomeric region of a chromosome.
70199	establishment of protein localization to chromosome	P	The directed movement of a protein to a specific location on a chromosome.
70200	establishment of protein localization to telomere	P	The directed movement of a protein to a specific location in the telomeric region of a chromosome.
70201	regulation of establishment of protein localization	P	Any process that modulates the frequency, rate or extent of the directed movement of a protein to a specific location.
70202	regulation of establishment of protein localization to chromosome	P	Any process that modulates the frequency, rate or extent of the directed movement of a protein to a specific location on a chromosome.
70203	regulation of establishment of protein localization to telomere	P	Any process that modulates the frequency, rate or extent of the directed movement of a protein to a specific location in the telomeric region of a chromosome.
70204	2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase activity	F	Catalysis of the reaction: 2-oxoglutarate + H(+) + isochorismate = 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1-carboxylate + CO(2).
70205	2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase activity	F	Catalysis of the reaction: 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1-carboxylate = (1R,6R)-2-succinyl-6-hydroxycyclohexa-2,4-diene-1-carboxylate + pyruvate.
70206	protein trimerization	P	The formation of a protein trimer, a macromolecular structure consisting of three noncovalently associated identical or nonidentical subunits.
70207	protein homotrimerization	P	The formation of a protein homotrimer, a macromolecular structure consisting of three noncovalently associated identical subunits.
70208	protein heterotrimerization	P	The formation of a protein heterotrimer, a macromolecular structure consisting of three noncovalently associated subunits, of which not all are identical.
70209	ASTRA complex	C	A protein complex that is part of the chromatin remodeling machinery; the acronym stands for ASsembly of Tel, Rvb and Atm-like kinase. In Saccharomyces cerevisiae this complex includes Rvb1p, Rvb2p, Tra1p, Tel2p, Asa1p, Ttilp and Tti2p.
70210	Rpd3L-Expanded complex	C	A protein complex that contains a histone deacetylase and is part of the chromatin remodeling machinery. In Saccharomyces cerevisiae this complex contains the Rpd3p, Sin3p, Ume1p, Pho23p, Sap30p, Sds3p, Cti6p, Rxt2p, Rxt3p, Dep1p, Ume6p, Ash1p, Dot6p, Snt1, Sif2p, Set3p, Hos2p, Tos4p and Tod6p proteins.
70211	Snt2C complex	C	A histone deacetylase complex that is part of the chromatin remodeling machinery. In Saccharomyces cerevisiae this complex contains Snt2p, Ecm5p and Rpd3p.
70212	protein poly-ADP-ribosylation	P	The transfer of multiple ADP-ribose residues from NAD to a protein amino acid, forming a poly(ADP-ribose) chain.
70213	protein auto-ADP-ribosylation	P	The ADP-ribosylation by a protein of one or more of its own amino acid residues, or residues on an identical protein.
70214	CSK-GAP-A.p62 complex	C	A protein complex that contains the protein-tyrosine kinase CSK and the GTPase-activating protein (GAP)-associated p62 (GAP-A.p62); may mediate translocation of proteins, including GAP and CSK, to membrane or cytoskeletal regions upon c-Src activation.
70217	transcription factor TFIIIB complex assembly	P	The aggregation, arrangement and bonding together of a set of components to form a transcription factor TFIIIB complex.
70218	sulfide ion homeostasis	P	Any process involved in the maintenance of an internal steady state of sulfide ions within an organism or cell.
70219	cellular sulfide ion homeostasis	P	Any process involved in the maintenance of an internal steady state of sulfide ions at the level of a cell.
70220	aerobic sulfur oxidation	P	A sulfur oxidation process that proceeds via the reaction catalyzed by sulfur dioxygenase, and requires the presence of oxygen.
70221	sulfide oxidation, using sulfide:quinone oxidoreductase	P	A sulfide oxidation process that proceeds via the reaction catalyzed by sulfide:quinone oxidoreductase.
70222	sulfide oxidation, using sulfide dehydrogenase	P	A sulfide oxidation process that proceeds via the reaction catalyzed by sulfide dehydrogenase.
70223	sulfide oxidation, using sulfur dioxygenase	P	A sulfide oxidation process that proceeds via the reaction catalyzed by sulfur dioxygenase.
70224	sulfide:quinone oxidoreductase activity	F	Catalysis of the reaction: hydrogen sulfide + a quinone = S0 + a hydroquinone.
70225	sulfide dehydrogenase activity	F	Catalysis of the reaction: hydrogen sulfide + oxidized cytochrome c = S0 + reduced cytochrome c.
70226	sulfur:ferric ion oxidoreductase activity	F	Catalysis of the reaction: a perthiol + 4 Fe3+ + 3 H2O = sulfite + a thiol + 4 Fe2+ + 8 H+.
70227	lymphocyte apoptotic process	P	Any apoptotic process in a lymphocyte, a leukocyte commonly found in the blood and lymph that has the characteristics of a large nucleus, a neutral staining cytoplasm, and prominent heterochromatin.
70228	regulation of lymphocyte apoptotic process	P	Any process that modulates the occurrence or rate of lymphocyte death by apoptotic process.
70229	negative regulation of lymphocyte apoptotic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of lymphocyte death by apoptotic process.
70230	positive regulation of lymphocyte apoptotic process	P	Any process that activates or increases the frequency, rate or extent of lymphocyte death by apoptotic process.
70231	T cell apoptotic process	P	Any apoptotic process in a T cell, a type of lymphocyte whose defining characteristic is the expression of a T cell receptor complex.
70232	regulation of T cell apoptotic process	P	Any process that modulates the occurrence or rate of T cell death by apoptotic process.
70233	negative regulation of T cell apoptotic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of T cell death by apoptotic process.
70234	positive regulation of T cell apoptotic process	P	Any process that activates or increases the frequency, rate or extent of T cell death by apoptotic process.
70235	regulation of activation-induced cell death of T cells	P	Any process that modulates the occurrence or rate of activation-induced cell death of T cells.
70236	negative regulation of activation-induced cell death of T cells	P	Any process that stops, prevents, or reduces the frequency, rate or extent of activation-induced cell death of T cells.
70237	positive regulation of activation-induced cell death of T cells	P	Any process that activates or increases the frequency, rate or extent of activation-induced cell death of T cells.
70238	activated T cell autonomous cell death	P	A T cell apoptotic process that occurs towards the end of the expansion phase following the initial activation of mature T cells by antigen via the accumulation of pro-apoptotic gene products and decrease in anti-apoptotic gene products.
70239	regulation of activated T cell autonomous cell death	P	Any process that modulates the occurrence or rate of activated T cell autonomous cell death.
70240	negative regulation of activated T cell autonomous cell death	P	Any process that stops, prevents, or reduces the frequency, rate or extent of activated T cell autonomous cell death.
70241	positive regulation of activated T cell autonomous cell death	P	Any process that activates or increases the frequency, rate or extent of activated T cell autonomous cell death.
70242	thymocyte apoptotic process	P	Any apoptotic process in a thymocyte, an immature T cell located in the thymus.
70243	regulation of thymocyte apoptotic process	P	Any process that modulates the occurrence or rate of thymocyte death by apoptotic process.
70244	negative regulation of thymocyte apoptotic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of thymocyte death by apoptotic process.
70245	positive regulation of thymocyte apoptotic process	P	Any process that activates or increases the frequency, rate or extent of thymocyte death by apoptotic process.
70246	natural killer cell apoptotic process	P	Any apoptotic process in a natural killer cell, a lymphocyte that can spontaneously kill a variety of target cells without prior antigenic activation.
70247	regulation of natural killer cell apoptotic process	P	Any process that modulates the occurrence or rate of natural killer cell death by apoptotic process.
70248	negative regulation of natural killer cell apoptotic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of natural killer cell death by apoptotic process.
70249	positive regulation of natural killer cell apoptotic process	P	Any process that activates or increases the frequency, rate or extent of natural killer cell death by apoptotic process.
70250	mating projection membrane	C	The portion of the plasma membrane surrounding a mating projection, the projection formed by unicellular fungi in response to mating pheromone.
70251	pristanate-CoA ligase activity	F	Catalysis of the reaction: ATP + pristanate + CoA = AMP + diphosphate + pristanoyl-CoA.
70252	actin-mediated cell contraction	P	The actin filament-based process in which cytoplasmic actin filaments slide past one another resulting in contraction of all or part of the cell body.
70253	somatostatin secretion	P	The regulated release of somatostatin from secretory granules in the D cells of the pancreas.
70254	mucus secretion	P	The regulated release of mucus by the mucosa. Mucus is a viscous slimy secretion consisting of mucins and various inorganic salts dissolved in water, with suspended epithelial cells and leukocytes. The mucosa, or mucous membrane, is the membrane covered with epithelium that lines the tubular organs of the body. Mucins are carbohydrate-rich glycoproteins that have a lubricating and protective function.
70255	regulation of mucus secretion	P	Any process that modulates the frequency, rate or extent of the regulated release of mucus from a cell or a tissue.
70256	negative regulation of mucus secretion	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of mucus from a cell or a tissue.
70257	positive regulation of mucus secretion	P	Any process that activates or increases the frequency, rate or extent of the regulated release of mucus from a cell or a tissue.
70258	inner membrane complex	C	A membrane structure formed of two closely aligned lipid bilayers that lie beneath the plasma membrane and form part of the pellicle surrounding an apicomplexan parasite cell.
70259	tyrosyl-DNA phosphodiesterase activity	F	Catalysis of the hydrolysis of phosphotyrosyl groups formed as covalent intermediates (in DNA backbone breakage) between a DNA topoisomerase and DNA.
70260	5'-tyrosyl-DNA phosphodiesterase activity	F	Catalysis of the hydrolysis of 5'-phosphotyrosyl groups formed as covalent intermediates (in DNA backbone breakage) between DNA topoisomerase II and DNA.
70262	peptidyl-serine dephosphorylation	P	The removal of phosphoric residues from peptidyl-O-phospho-L-serine to form peptidyl-serine.
70263	external side of fungal-type cell wall	C	The side of the fungal-type cell wall that is opposite to the side that faces the cell and its contents.
70264	transcription factor TFIIIE complex	C	A transcription factor complex that is involved in regulating transcription from RNA polymerase III (Pol III) promoters. TFIIIE contains a specific subset of ribosomal proteins.
70265	necrotic cell death	P	A type of cell death that is morphologically characterized by an increasingly translucent cytoplasm, swelling of organelles, minor ultrastructural modifications of the nucleus (specifically, dilatation of the nuclear membrane and condensation of chromatin into small, irregular, circumscribed patches) and increased cell volume (oncosis), culminating in the disruption of the plasma membrane and subsequent loss of intracellular contents. Necrotic cells do not fragment into discrete corpses as their apoptotic counterparts do. Moreover, their nuclei remain intact and can aggregate and accumulate in necrotic tissues.
70266	necroptotic process	P	A programmed necrotic cell death process which begins when a cell receives a signal (e.g. a ligand binding to a death receptor or to a Toll-like receptor), and proceeds through a series of biochemical events (signaling pathways), characterized by activation of receptor-interacting serine/threonine-protein kinase 1 and/or 3 (RIPK1/3, also called RIP1/3) and by critical dependence on mixed lineage kinase domain-like (MLKL), and which typically lead to common morphological features of necrotic cell death. The process ends when the cell has died. The process is divided into a signaling phase, and an execution phase, which is triggered by the former.
70267	oncosis	P	A cellular process that results in swelling of the cell body, and that is morphologically characteristic of necrotic cell death.
70268	cornification	P	A type of programmed cell death that occurs in the epidermis, morphologically and biochemically distinct from apoptosis. It leads to the formation of corneocytes, i.e. dead keratinocytes containing an amalgam of specific proteins (e.g., keratin, loricrin, SPR and involucrin) and lipids (e.g., fatty acids and ceramides), which are necessary for the function of the cornified skin layer (mechanical resistance, elasticity, water repellence and structural stability).
70269	pyroptosis	P	A caspase-1-dependent cell death subroutine that is associated with the generation of pyrogenic mediators such as IL-1beta and IL-18.
70271	protein complex biogenesis	P	A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a protein complex. Includes the synthesis of non-protein components, and those protein modifications that are involved in synthesis or assembly of the complex.
70272	proton-transporting ATP synthase complex biogenesis	P	The biogenesis of a proton-transporting ATP synthase (also known as F-type ATPase), a two-sector ATPase found in the inner membrane of mitochondria and chloroplasts, and in bacterial plasma membranes. Includes the synthesis of constituent proteins and their aggregation, arrangement and bonding together.
70273	phosphatidylinositol-4-phosphate binding	F	Interacting selectively and non-covalently with phosphatidylinositol-4-phosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 4' position.
70274	RES complex	C	A protein complex that is required for efficient splicing, and prevents leakage of unspliced pre-mRNAs from the nucleus (named for pre-mRNA REtention and Splicing). In Saccharomyces, the complex consists of Ist3p, Bud13p, and Pml1p.
70275	aerobic ammonia oxidation to nitrite via pyruvic oxime	P	The metabolic process in which ammonia (NH3) is oxidized to nitrite (NO2) in the presence of oxygen. Hydroxylamine is produced enzymatically, and, in the presence of pyruvate, forms pyruvic oxime in a spontaneous, non-enzymatic reaction; pyruvic oxime is then converted to nitrite.
70276	halogen metabolic process	P	The chemical reactions and pathways involving any halogen, elements of Group VII; includes metabolism of halogen-containing compounds.
70277	iodide oxidation	P	The chemical reactions and pathways by which iodide is converted to diiodine, with the concomitant loss of electrons.
70278	extracellular matrix constituent secretion	P	The controlled release of molecules that form the extracellular matrix, including carbohydrates and glycoproteins by a cell.
70279	vitamin B6 binding	F	Interacting selectively and non-covalently with any of the vitamin B6 compounds: pyridoxal, pyridoxamine and pyridoxine and the active form, pyridoxal phosphate.
70280	pyridoxal binding	F	Interacting selectively and non-covalently with pyridoxal, 3-hydroxy-5-(hydroxymethyl)-2-methylpyridine-4-carbaldehyde, a form of vitamin B6.
70281	pyridoxamine binding	F	Interacting selectively and non-covalently with pyridoxamine, 4-(aminomethyl)-5-(hydroxymethyl)-2-methylpyridin-3-ol, a form of vitamin B6.
70282	pyridoxine binding	F	Interacting selectively and non-covalently with pyridoxine, 4,5-bis(hydroxymethyl)-2-methylpyridin-3-ol, a form of vitamin B6.
70283	radical SAM enzyme activity	F	Catalysis of a reaction in which S-adenosyl-L-methionine (SAM) undergoes reductive cleavage to serve as a source of the 5'-deoxyadenosyl radical.
70284	4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase activity	F	Catalysis of the reaction: 5-aminoimidazole ribonucleotide + S-adenosylmethionine = 4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate + 5'deoxyadenosine.
70285	pigment cell development	P	The process whose specific outcome is the progression of a pigment cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a pigment cell fate.
70286	axonemal dynein complex assembly	P	The aggregation, arrangement and bonding together of a set of components to form an axonemal dynein complex, a dynein complex found in eukaryotic cilia and flagella, in which the motor domain heads interact with adjacent microtubules to generate a sliding force which is converted to a bending motion.
70287	ferritin receptor activity	F	Combining with ferritin, and delivering ferritin into the cell via endocytosis.
70288	ferritin complex	C	A protein complex that binds iron and acts as a major iron storage system. Intracellular and extracellular ferritin complexes have different ratios of two types of ferritin monomer, the L (light) chain and H (heavy) chain.
70289	extracellular ferritin complex	C	A ferritin complex located in the extracellular region. Extracellular ferritin complexes contain L (light) chains but few or no H (heavy) chains.
70290	N-acylphosphatidylethanolamine-specific phospholipase D activity	F	Catalysis of the release of N-acylethanolamine from N-acyl-phosphatidylethanolamine (NAPE) to generate N-acylethanolamine (NAE).
70291	N-acylethanolamine metabolic process	P	The chemical reactions and pathways involving N-acylethanolamines. An N-acylethanolamine is an ethanolamine substituted at nitrogen by an acyl group.
70292	N-acylphosphatidylethanolamine metabolic process	P	The chemical reactions and pathways involving N-acylphosphatidylethanolamines. An N-acylphosphatidylethanolamine is a phosphatidylethanolamine substituted at nitrogen by an acyl group.
70293	renal absorption	P	A renal system process in which water, ions, glucose and proteins are taken up from the collecting ducts, glomerulus and proximal and distal loops of the nephron. In non-mammalian species, absorption may occur in related structures (e.g. protein absorption is observed in nephrocytes in Drosophila, see PMID:23264686).
70294	renal sodium ion absorption	P	A renal system process in which sodium ions are taken up from the collecting ducts and proximal and distal loops of the nephron. In non-mammalian species, absorption may occur in related structures.
70295	renal water absorption	P	A renal system process in which water is taken up from the collecting ducts and proximal and distal loops of the nephron. In non-mammalian species, absorption may occur in related structures.
70296	sarcoplasmic reticulum calcium ion transport	P	The directed movement of calcium ions (Ca2+) into, out of or within the sarcoplasmic reticulum.
70297	regulation of phosphorelay signal transduction system	P	Any process that modulates the frequency, rate or extent of signal transduction via a phosphorelay signal transduction system.
70298	negative regulation of phosphorelay signal transduction system	P	Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction via a phosphorelay signal transduction system.
70299	positive regulation of phosphorelay signal transduction system	P	Any process that activates or increases the frequency, rate or extent of signal transduction via a phosphorelay signal transduction system.
70300	phosphatidic acid binding	F	Interacting selectively and non-covalently with phosphatidic acid, any of a class of glycerol phosphate in which both the remaining hydroxyl groups of the glycerol moiety are esterified with fatty acids.
70301	cellular response to hydrogen peroxide	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrogen peroxide (H2O2) stimulus.
70302	regulation of stress-activated protein kinase signaling cascade	P	Any process that modulates the frequency, rate or extent of signaling via a stress-activated protein kinase signaling cascade.
70303	negative regulation of stress-activated protein kinase signaling cascade	P	Any process that stops, prevents, or reduces the frequency, rate or extent of signaling via the stress-activated protein kinase signaling cascade.
70304	positive regulation of stress-activated protein kinase signaling cascade	P	Any process that activates or increases the frequency, rate or extent of signaling via the stress-activated protein kinase signaling cascade.
70305	response to cGMP	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cGMP (cyclic GMP, guanosine 3',5'-cyclophosphate) stimulus.
70306	lens fiber cell differentiation	P	The process in which a relatively unspecialized cell acquires specialized features of a lens fiber cell, any of the elongated, tightly packed cells that make up the bulk of the mature lens in the camera-type eye. The cytoplasm of a lens fiber cell is devoid of most intracellular organelles including the cell nucleus, and contains primarily crystallins, a group of water-soluble proteins expressed in vary large quantities.
70307	lens fiber cell development	P	The process whose specific outcome is the progression of a lens fiber cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a lens fiber cell fate. A lens fiber cell is any of the elongated, tightly packed cells that make up the bulk of the mature lens in a camera-type eye.
70308	lens fiber cell fate commitment	P	The process in which the developmental fate of a cell becomes restricted such that it will develop into a lens fiber cell. A lens fiber cell is any of the elongated, tightly packed cells that make up the bulk of the mature lens in a camera-type eye.
70309	lens fiber cell morphogenesis	P	The process in which the structures of a lens fiber cell are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a lens fiber cell. A lens fiber cell is any of the elongated, tightly packed cells that make up the bulk of the mature lens in a camera-type eye.
70310	ATR-ATRIP complex	C	A protein complex that contains the protein kinase ATR and ATR-interacting protein (ATRIP) and binds single-stranded DNA; ssDNA binding affinity is increased in the presence of replication protein A.
70311	nucleosomal methylation activator complex	C	A protein complex that contains eight subunits in common with the SWI/SNF complex, plus the ATPase BRG1 (SMARCA4) and the histone methyltransferase CARM1; the complex is involved in regulating nuclear receptor-dependent transcription.
70312	RAD52-ERCC4-ERCC1 complex	C	A nucleotide-excision repair complex formed by the association of the heterodimeric endonuclease XPF/ERCC4-ERCC1 (Rad1p and Rad10p in S. cerevisiae) with the RAD52 protein.
70313	RGS6-DNMT1-DMAP1 complex	C	A protein complex formed by the association of RGS6, a negative regulator of heterotrimeric G protein signaling, with the DMAP1-Dnmt1 transcriptional repressor complex; in the complex, RGS6 inhibits the transcriptional repressor activity of DMAP1.
70314	G1 to G0 transition	P	A cell cycle arrest process that results in arrest during G1 phase, whereupon the cell enters a specialized resting state known as G0 or quiescence.
70315	G1 to G0 transition involved in cell differentiation	P	A cell cycle arrest process that results in arrest during G1 phase, whereupon the cell enters G0 phase, in the context of cell differentiation.
70316	regulation of G0 to G1 transition	P	A cell cycle process that modulates the rate or extent of the transition from the G0 quiescent state to the G1 phase.
70317	negative regulation of G0 to G1 transition	P	A cell cycle process that stops, prevents, or reduces the rate or extent of the transition from the G0 quiescent state to the G1 phase.
70318	positive regulation of G0 to G1 transition	P	A cell cycle process that activates or increases the rate or extent of the transition from the G0 quiescent state to the G1 phase.
70319	Golgi to plasma membrane transport vesicle	C	A transport vesicle that mediates transport from the Golgi to the plasma membrane, and fuses with the plasma membrane to release various cargo molecules, such as proteins or hormones, by exocytosis.
70320	inward rectifier potassium channel inhibitor activity	F	Stops, prevents, or reduces the activity of an inwardly rectifying potassium channel.
70321	regulation of translation in response to nitrogen starvation	P	Any process that modulates the frequency, rate or extent of the frequency, rate or extent of translation as a result of a stimulus indicating deprivation of nitrogen.
70322	negative regulation of translation in response to nitrogen starvation	P	Any process that stops, prevents or reduces the rate of translation as a result of a stimulus indicating deprivation of nitrogen.
70323	positive regulation of translation in response to nitrogen starvation	P	Any process that activates or increases the frequency, rate or extent of translation as a result of a stimulus indicating deprivation of nitrogen.
70324	thyroid hormone binding	F	Interacting selectively and non-covalently with thyroxine (T4) or triiodothyronine (T3), tyrosine-based hormones produced by the thyroid gland.
70325	lipoprotein particle receptor binding	F	Interacting selectively and non-covalently with a lipoprotein particle receptor.
70326	very-low-density lipoprotein particle receptor binding	F	Interacting selectively and non-covalently with a very-low-density lipoprotein receptor.
70327	thyroid hormone transport	P	The directed movement of thyroid hormone into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
70328	triglyceride homeostasis	P	Any process involved in the maintenance of an internal steady state of triglyceride within an organism or cell.
70329	tRNA seleno-modification	P	The substitution of a selenium atom for a sulfur atom in a ribonucleotide in a tRNA molecule.
70330	aromatase activity	F	Catalysis of the reduction of an aliphatic ring to yield an aromatic ring.
70331	CD20-Lck-Fyn complex	C	A protein complex that contains the cell-surface protein CD20 and the Src family tyrosine kinases Lck and Fyn.
70332	CD20-Lck-Lyn-Fyn complex	C	A protein complex that contains the cell-surface protein CD20 and the Src family tyrosine kinases Lck, Lyn and Fyn.
70333	alpha6-beta4 integrin-Shc-Grb2 complex	C	A protein complex that consists of an alpha6-beta4 integrin complex bound to the adaptor proteins Shc and Grb2.
70334	alpha6-beta4 integrin-laminin 5 complex	C	A protein complex that consists of an alpha6-beta4 integrin complex bound to laminin 5.
70335	aspartate binding	F	Interacting selectively and non-covalently with aspartate, the alpha-amino-acid anion of 2-aminobutanedioic acid that has formula C4H5NO4.
70336	flap-structured DNA binding	F	Interacting selectively and non-covalently with a flap structure in DNA. A DNA flap structure is one in which a single-stranded length of DNA or RNA protrudes from a double-stranded DNA molecule.
70337	3'-flap-structured DNA binding	F	Interacting selectively and non-covalently with a 3'-flap structure in DNA. A DNA flap structure is one in which a single-stranded 3'-end of DNA or RNA protrudes from a double-stranded DNA molecule.
70338	5'-flap-structured DNA binding	F	Interacting selectively and non-covalently with a 5'-flap structure in DNA. A DNA flap structure is one in which a single-stranded 5'-end of DNA or RNA protrudes from a double-stranded DNA molecule. 5'-flap structures can be formed during DNA repair or lagging strand synthesis; in the latter case RNA flaps form from lagging strand RNA primers.
70339	response to bacterial lipopeptide	P	Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bacterial lipopeptide stimulus.
70340	detection of bacterial lipopeptide	P	The series of events in which a bacterial lipopeptide stimulus is received by a cell and converted into a molecular signal.
70341	fat cell proliferation	P	The multiplication or reproduction of fat cells by cell division, resulting in the expansion of their population. A fat cell is an animal connective tissue cell specialized for the synthesis and storage of fat.
70342	brown fat cell proliferation	P	The multiplication or reproduction of brown fat cells by cell division, resulting in the expansion of their population. A brown fat cell is a fat cell found the thermogenic form of adipose tissue found in newborns of many species.
70343	white fat cell proliferation	P	The multiplication or reproduction of white fat cells by cell division, resulting in the expansion of their population.
70344	regulation of fat cell proliferation	P	Any process that modulates the frequency, rate or extent of fat cell proliferation.
70345	negative regulation of fat cell proliferation	P	Any process that stops or decreases the rate or extent of fat cell proliferation.
70346	positive regulation of fat cell proliferation	P	Any process that activates or increases the rate or extent of fat cell proliferation.
70347	regulation of brown fat cell proliferation	P	Any process that modulates the frequency, rate or extent of brown fat cell proliferation.
70348	negative regulation of brown fat cell proliferation	P	Any process that stops or decreases the rate or extent of brown fat cell proliferation.
70349	positive regulation of brown fat cell proliferation	P	Any process that activates or increases the rate or extent of brown fat cell proliferation.
70350	regulation of white fat cell proliferation	P	Any process that modulates the frequency, rate or extent of white fat cell proliferation.
70351	negative regulation of white fat cell proliferation	P	Any process that stops or decreases the rate or extent of white fat cell proliferation.
70352	positive regulation of white fat cell proliferation	P	Any process that activates or increases the rate or extent of white fat cell proliferation.
70353	GATA1-TAL1-TCF3-Lmo2 complex	C	A protein complex that contains the zinc finger transcription factor GATA1, the LIM domain protein Lmo2 (RBTN2), the basic helix-loop-helix protein TAL1 and its binding partner TCF3. The complex is involved transcriptional regulation in hematopoiesis.
70354	GATA2-TAL1-TCF3-Lmo2 complex	C	A protein complex that contains the zinc finger transcription factor GATA2, the LIM domain protein Lmo2 (RBTN2), the basic helix-loop-helix protein TAL1 and its binding partner TCF3. The complex is involved transcriptional regulation in hematopoiesis.
70355	synaptotagmin-synaptobrevin 2-SNAP-25-syntaxin-1a-syntaxin-1b-Rab3a-complexin II complex	C	A SNARE complex that contains synaptotagmin, synaptobrevin 2 (VAMP2), SNAP-25, syntaxin 1a, syntaxin1b, Rab3a, and complexin II (or orthologs thereof).
70356	synaptotagmin-synaptobrevin 2-SNAP-25-syntaxin-1a-syntaxin-1b-Rab3a complex	C	A SNARE complex that contains synaptotagmin, synaptobrevin 2 (VAMP2), SNAP-25, syntaxin 1a, syntaxin1b, and Rab3a (or orthologs thereof).
70357	alphav-beta3 integrin-CD47 complex	C	A protein complex that consists of an alphav-beta3 integrin complex bound to CD47 (also known as IAP).
70358	actin polymerization-dependent cell motility	P	A process involved in the controlled movement of a bacterial cell powered by the continuous polymerization of actin at one pole of the cell.
70359	actin polymerization-dependent cell motility involved in migration of symbiont in host	P	A process involved in the controlled movement of a bacterial cell within a host cell, powered by the continuous polymerization of host actin at one pole of the cell.
70360	migration of symbiont within host by polymerization of host actin	P	The directional movement of an organism, usually a bacterial cell, from one place to another within its host organism, by a process involving continuous polymerization of host actin at one pole of the symbiont cell. The host is defined as the larger of the organisms involved in a symbiotic interaction.
70361	mitochondrial light strand promoter anti-sense binding	F	Interacting selectively and non-covalently with the anti-sense strand of the light strand promoter, a promoter located on the light, or cytosine-rich, strand of mitochondrial DNA.
70362	mitochondrial heavy strand promoter anti-sense binding	F	Interacting selectively and non-covalently with the anti-sense strand of the heavy strand promoter, a promoter located on the heavy, or guanine-rich, strand of mitochondrial DNA.
70363	mitochondrial light strand promoter sense binding	F	Interacting selectively and non-covalently with the sense strand of the light strand promoter, a promoter located on the light, or cytosine-rich, strand of mitochondrial DNA.
70364	mitochondrial heavy strand promoter sense binding	F	Interacting selectively and non-covalently with the sense strand of the heavy strand promoter, a promoter located on the heavy, or guanine-rich, strand of mitochondrial DNA.
70365	hepatocyte differentiation	P	The process in which a relatively unspecialized cell acquires the specialized features of a hepatocyte. A hepatocyte is specialized epithelial cell that is organized into interconnected plates called lobules, and is the main structural component of the liver.
70366	regulation of hepatocyte differentiation	P	Any process that modulates the frequency, rate or extent of hepatocyte differentiation.
70367	negative regulation of hepatocyte differentiation	P	Any process that stops or decreases the rate or extent of hepatocyte differentiation.
70368	positive regulation of hepatocyte differentiation	P	Any process that activates or increases the rate or extent of hepatocyte differentiation.
70369	beta-catenin-TCF7L2 complex	C	A protein complex that contains beta-catenin and TCF7L2 (TCF4), binds to the TCF DNA motif within a promoter element, and is involved in the regulation of WNT target gene transcription.
70370	cellular heat acclimation	P	Any process that increases heat tolerance of a cell in response to high temperatures.
70371	ERK1 and ERK2 cascade	P	An intracellular protein kinase cascade containing at least ERK1 or ERK2 (MAPKs), a MEK (a MAPKK) and a MAP3K. The cascade can also contain two additional tiers: the upstream MAP4K and the downstream MAP Kinase-activated kinase (MAPKAPK). The kinases in each tier phosphorylate and activate the kinases in the downstream tier to transmit a signal within a cell.
70372	regulation of ERK1 and ERK2 cascade	P	Any process that modulates the frequency, rate or extent of signal transduction mediated by the ERK1 and ERK2 cascade.
70373	negative regulation of ERK1 and ERK2 cascade	P	Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the ERK1 and ERK2 cascade.
70374	positive regulation of ERK1 and ERK2 cascade	P	Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the ERK1 and ERK2 cascade.
70375	ERK5 cascade	P	An intracellular protein kinase cascade containing at least ERK5 (also called BMK1; a MAPK), a MEK (a MAPKK) and a MAP3K. The cascade can also contain two additional tiers: the upstream MAP4K and the downstream MAP Kinase-activated kinase (MAPKAPK). The kinases in each tier phosphorylate and activate the kinases in the downstream tier to transmit a signal within a cell.
70376	regulation of ERK5 cascade	P	Any process that modulates the frequency, rate or extent of signal transduction mediated by the ERK5 cascade.
70377	negative regulation of ERK5 cascade	P	Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the ERK5 cascade.
70378	positive regulation of ERK5 cascade	P	Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the ERK5 cascade.
70379	high mobility group box 1 binding	F	Interacting selectively and non-covalently with high mobility group box 1 (HMBGB1).
70380	high mobility group box 1 receptor activity	F	Combining with high mobility group box 1 (HMBGB1) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
70381	endosome to plasma membrane transport vesicle	C	A transport vesicle that mediates transport from the endosome to the plasma membrane, and fuses with the plasma membrane to deliver lipids and membrane proteins to the plasma membrane and to release various cargo molecules, such as proteins or hormones, by exocytosis.
70382	exocytic vesicle	C	A transport vesicle that mediates transport from an intracellular compartment to the plasma membrane, and fuses with the plasma membrane to release various cargo molecules, such as proteins or hormones, by exocytosis.
70383	DNA cytosine deamination	P	The removal of an amino group from a cytosine residue in DNA, forming a uracil residue.
70384	Harderian gland development	P	The process whose specific outcome is the progression of the Harderian gland over time, from its formation to the mature structure. The Harderian gland is an anterior orbital structure usually associated with the nictitating membrane, and produces and secretes a variety of substances to the eye, depending upon the species.
70385	egasyn-beta-glucuronidase complex	C	A protein complex that contains beta-glucuronidase and the carboxyl esterase egasyn; formation of the complex causes beta-glucuronidase to be retained in the endoplasmic reticulum.
70386	procollagen-proline 4-dioxygenase complex, alpha(I) type	C	A procollagen-proline 4-dioxygenase complex that contains alpha subunits of the type I isoform; its activity is readily inhibited by poly(L-proline).
70387	procollagen-proline 4-dioxygenase complex, alpha(II) type	C	A procollagen-proline 4-dioxygenase complex that contains alpha subunits of the type II isoform; its activity is inhibited by poly(L-proline) only at high concentrations.
70388	procollagen-proline 4-dioxygenase complex, alpha(III) type	C	A procollagen-proline 4-dioxygenase complex that contains alpha subunits of the type III isoform.
70389	chaperone cofactor-dependent protein refolding	P	The process of assisting in the restoration of the biological activity of an unfolded or misfolded protein, which is dependent on additional protein cofactors. This process occurs over one or several cycles of nucleotide hydrolysis-dependent binding and release.
70390	transcription export complex 2	C	A protein complex that couples SAGA-dependent gene expression to mRNA export at the inner side of the nuclear pore complex (NPC). The TREX-2 complex is tethered to the inner side of the NPC via the nucleoporins Nup1 and Nup60; in S. cerevisiae it contains Sac3p, Thp1p, Sus1p and Cdc31p.
70391	response to lipoteichoic acid	P	Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipoteichoic acid stimulus; lipoteichoic acid is a major component of the cell wall of gram-positive bacteria and typically consists of a chain of glycerol-phosphate repeating units linked to a glycolipid anchor.
70392	detection of lipoteichoic acid	P	The series of events in which a lipoteichoic acid stimulus is received by a cell and converted into a molecular signal; lipoteichoic acid is a major component of the cell wall of gram-positive bacteria and typically consists of a chain of glycerol-phosphate repeating units linked to a glycolipid anchor.
70393	teichoic acid catabolic process	P	The chemical reactions and pathways resulting in the breakdown of teichoic acid, which is a major component of the cell wall of Gram-positive bacteria and typically consists of a polymer of glycerol-phosphate or ribitol-phosphate to which are attached glycosyl and D-alanyl ester residues.
70394	lipoteichoic acid metabolic process	P	The chemical reactions and pathways involving lipoteichoic acid, which is a major component of the cell wall of gram-positive bacteria and typically consists of a chain of glycerol-phosphate repeating units linked to a glycolipid anchor.
70395	lipoteichoic acid biosynthetic process	P	The chemical reactions and pathways resulting in the formation of lipoteichoic acid, which is a major component of the cell wall of gram-positive bacteria and typically consists of a chain of glycerol-phosphate repeating units linked to a glycolipid anchor.
70396	lipoteichoic acid catabolic process	P	The chemical reactions and pathways resulting in the breakdown of lipoteichoic acid, which is a major component of the cell wall of gram-positive bacteria and typically consists of a chain of glycerol-phosphate repeating units linked to a glycolipid anchor.
70397	wall teichoic acid metabolic process	P	The chemical reactions and pathways involving wall teichoic acid, which is a major component of the cell wall of Gram-positive bacteria and typically consists of a polymer of glycerol-phosphate or ribitol-phosphate to which are attached glycosyl and D-alanyl ester residues and which is covalently linked to peptidoglycan.
70398	wall teichoic acid biosynthetic process	P	The chemical reactions and pathways resulting in the formation of wall teichoic acid, which is a major component of the cell wall of Gram-positive bacteria and typically consists of a polymer of glycerol-phosphate or ribitol-phosphate to which are attached glycosyl and D-alanyl ester residues and which is covalently linked to peptidoglycan.
70399	wall teichoic acid catabolic process	P	The chemical reactions and pathways resulting in the breakdown of wall teichoic acid, which is a major component of the cell wall of Gram-positive bacteria and typically consists of a polymer of glycerol-phosphate or ribitol-phosphate to which are attached glycosyl and D-alanyl ester residues and which is covalently linked to peptidoglycan.
70400	teichoic acid D-alanylation	P	The formation of a D-alanyl ester of teichoic acid. Alanylation of teichoic acids modulates the properties of the bacterial cell wall and modulates the inflammatory properties of the teichoic acid.
70401	NADP+ binding	F	Interacting selectively and non-covalently with the oxidized form, NADP+, of nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions.
70402	NADPH binding	F	Interacting selectively and non-covalently with the reduced form, NADPH, of nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions.
70403	NAD+ binding	F	Interacting selectively and non-covalently with the oxidized form, NAD, of nicotinamide adenine dinucleotide, a coenzyme involved in many redox and biosynthetic reactions.
70404	NADH binding	F	Interacting selectively and non-covalently with the reduced form, NADH, of nicotinamide adenine dinucleotide, a coenzyme involved in many redox and biosynthetic reactions.
70405	ammonium ion binding	F	Interacting selectively and non-covalently with ammonium ions (NH4+).
70406	glutamine binding	F	Interacting selectively and non-covalently with glutamine, 2,5-diamino-5-oxopentanoic acid.
70407	oxidation-dependent protein catabolic process	P	The chemical reactions and pathways resulting in the breakdown of a protein or peptide by hydrolysis of its peptide bonds, initiated by the oxidation of one or more amino acid residues in the protein.
70408	carbamoyl phosphate metabolic process	P	The chemical reactions and pathways involving carbamoyl phosphate, an intermediate in the urea cycle and other nitrogen compound metabolic pathways.
70409	carbamoyl phosphate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of carbamoyl phosphate, an intermediate in the urea cycle and other nitrogen compound metabolic pathways.
70410	co-SMAD binding	F	Interacting selectively and non-covalently with a common mediator SMAD signaling protein.
70411	I-SMAD binding	F	Interacting selectively and non-covalently with an inhibitory SMAD signaling protein.
70412	R-SMAD binding	F	Interacting selectively and non-covalently with a receptor-regulated SMAD signaling protein.
70413	trehalose metabolism in response to stress	P	The chemical reactions and pathways involving trehalose that occur as a result of a stimulus indicating the organism is under stress.
70414	trehalose metabolism in response to heat stress	P	The chemical reactions and pathways involving trehalose that occur as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.
70415	trehalose metabolism in response to cold stress	P	The chemical reactions and pathways involving trehalose that occur as a result of a cold stimulus, a temperature stimulus below the optimal temperature for that organism.
70416	trehalose metabolism in response to water deprivation	P	The chemical reactions and pathways involving trehalose that occur as a result of deprivation of water.
70417	cellular response to cold	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cold stimulus, a temperature stimulus below the optimal temperature for that organism.
70418	DNA-dependent protein kinase complex	C	A protein complex that is involved in the repair of DNA double-strand breaks and, in mammals, V(D)J recombination events. It consists of the DNA-dependent protein kinase catalytic subunit (DNA-PKcs) and the DNA end-binding heterodimer Ku.
70419	nonhomologous end joining complex	C	A protein complex that plays a role in DNA double-strand break repair via nonhomologous end joining. Such complexes typically contain a specialized DNA ligase (e.g. Lig4 in eukaryotes) and one or more proteins that bind to DNA ends.
70420	Ku-DNA ligase complex	C	A nonhomologous end joining complex that contains one or more Ku monomers and one or more DNA ligase molecules from the LigC or LigD family, and mediates nonhomologous end joining in bacteria.
70421	DNA ligase III-XRCC1 complex	C	A protein complex that contains DNA ligase III and XRCC1, and is involved in base excision repair.
70422	G-protein beta/gamma-Raf-1 complex	C	A protein complex formed by the association of the serine-threonine protein kinase Raf-1 with the beta and gamma subunits of a heterotrimeric G protein.
70423	nucleotide-binding oligomerization domain containing signaling pathway	P	Any series of molecular signals generated as a consequence of binding to a nucleotide-binding oligomerization domain containing (NOD) protein.
70424	regulation of nucleotide-binding oligomerization domain containing signaling pathway	P	Any process that modulates the frequency, rate, or extent of a nucleotide-binding oligomerization domain containing (NOD) pathway.
70425	negative regulation of nucleotide-binding oligomerization domain containing signaling pathway	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of the nucleotide-binding oligomerization domain containing (NOD) pathway.
70426	positive regulation of nucleotide-binding oligomerization domain containing signaling pathway	P	Any process that activates or increases the frequency, rate, or extent of the nucleotide-binding oligomerization domain containing (NOD) pathway.
70427	nucleotide-binding oligomerization domain containing 1 signaling pathway	P	Any series of molecular signals generated as a consequence of binding to nucleotide-binding oligomerization domain containing 1 (NOD1).
70428	regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway	P	Any process that modulates the frequency, rate, or extent of the nucleotide-binding oligomerization domain containing 1 (NOD1) pathway.
70429	negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of the nucleotide-binding oligomerization domain containing 1 (NOD1) pathway.
70430	positive regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway	P	Any process that activates or increases the frequency, rate, or extent of the nucleotide-binding oligomerization domain containing 1 (NOD1) pathway.
70431	nucleotide-binding oligomerization domain containing 2 signaling pathway	P	Any series of molecular signals generated as a consequence of binding to nucleotide-binding oligomerization domain containing 2 (NOD2).
70432	regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway	P	Any process that modulates the frequency, rate, or extent of the nucleotide-binding oligomerization domain containing 2 (NOD2) pathway.
70433	negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of the nucleotide-binding oligomerization domain containing 2 (NOD2) pathway.
70434	positive regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway	P	Any process that activates or increases the frequency, rate, or extent of the nucleotide-binding oligomerization domain containing 2 (NOD2) pathway.
70435	Shc-EGFR complex	C	A protein complex that contains the epidermal growth factor receptor (EGFR) and the adaptor protein Shc, and is involved in linking EGFR activation to the p21-Ras pathway.
70436	Grb2-EGFR complex	C	A protein complex that contains the epidermal growth factor receptor (EGFR) and Grb2, and is involved in linking EGFR activation to the p21-Ras pathway.
70437	Grb2-Shc complex	C	A protein complex that contains Grb2 and the adaptor protein Shc, and is involved in linking epidermal growth factor receptor (EGFR) activation to the p21-Ras pathway.
70439	Mad-Max-mSin3A complex	C	A transcriptional repressor complex that contains a heterodimer of the bHLH-ZIP proteins Mad and Max, plus mSin3A, a homolog of the yeast Sin3p.
70440	Mad-Max-mSin3B complex	C	A transcriptional repressor complex that contains a heterodimer of the bHLH-ZIP proteins Mad and Max, plus mSin3B, a homolog of the yeast Sin3p.
70441	G-protein beta/gamma-Btk complex	C	A protein complex formed by the association of the Bruton tyrosine protein kinase Btk, which is implicated in mammalian X-linked immunodeficiencies, with the beta and gamma subunits of a heterotrimeric G protein.
70442	integrin alphaIIb-beta3 complex	C	An integrin complex that comprises one alphaIIb subunit and one beta3 subunit.
70443	Mad-Max complex	C	A transcriptional repressor complex that consists of a heterodimer of the bHLH-ZIP proteins Mad and Max.
70444	oligodendrocyte progenitor proliferation	P	The multiplication or reproduction of oligodendrocyte progenitor cells by cell division, resulting in the expansion of their population. Oligodendrocyte progenitors give rise to oligodendrocytes, which form the insulating myelin sheath of axons in the central nervous system.
70445	regulation of oligodendrocyte progenitor proliferation	P	Any process that modulates the frequency, rate or extent of oligodendrocyte progenitor proliferation.
70446	negative regulation of oligodendrocyte progenitor proliferation	P	Any process that stops or decreases the rate or extent of oligodendrocyte progenitor proliferation.
70447	positive regulation of oligodendrocyte progenitor proliferation	P	Any process that activates or increases the rate or extent of oligodendrocyte progenitor proliferation.
70448	laricitrin 5'-O-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + laricitrin = S-adenosyl-L-homocysteine + syringetin.
70449	elongin complex	C	A transcription elongation factor complex that suppresses RNA polymerase II pausing, and may act by promoting proper alignment of the 3'-end of nascent transcripts with the polymerase catalytic site. Consists of a transcriptionally active Elongin A subunit (abut 100 kDa)and two smaller Elongin B (about 18 kDa) and Elongin C (about 15 kDa)subunits.
70450	interleukin4-interleukin-4 receptor complex	C	A protein complex that is formed by the association of a heterodimeric interleukin-4 receptor complex with an interleukin-4 molecule.
70451	cell hair	C	A long, thin cell projection that contains F-actin and tubulin, with microtubules centrally located and F-actin peripherally located.
70452	positive regulation of ergosterol biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of ergosterol.
70453	regulation of heme biosynthetic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of heme.
70454	negative regulation of heme biosynthetic process	P	Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of heme.
70455	positive regulation of heme biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of heme.
70456	galactose-1-phosphate phosphatase activity	F	Catalysis of the reaction: galactose-1-phosphate + H2O = galactose + phosphate.
70457	D-galactose-1-phosphate phosphatase activity	F	Catalysis of the reaction: D-galactose-1-phosphate + H2O = D-galactose + phosphate.
70458	cellular detoxification of nitrogen compound	P	Any cellular process that reduces or removes the toxicity of nitrogenous compounds which are dangerous or toxic. This includes the aerobic conversion of toxic compounds to harmless substances.
70459	prolactin secretion	P	The regulated release of prolactin, a peptide hormone that stimulates lactation, from secretory granules in the anterior pituitary.
70460	thyroid-stimulating hormone secretion	P	The regulated release of thyroid-stimulating hormone, a peptide hormone that stimulates the activity of the thyroid gland, from secretory granules in the anterior pituitary.
70461	SAGA-type complex	C	A histone acetyltransferase complex that acetylates nucleosomal H3 and H2B and is required for the expression of a subset of Pol II-transcribed genes. The budding yeast complex includes the acetyltransferase Gcn5p, several proteins of the Spt and Ada families, and several TBP-associate proteins (TAFs); analogous complexes in other species have analogous compositions, and usually contain homologs of the yeast proteins.
70462	plus-end specific microtubule depolymerization	P	The removal of tubulin heterodimers from the plus end of a microtubule.
70463	tubulin-dependent ATPase activity	F	Catalysis of the reaction: ATP + H2O = ADP + phosphate. This reaction requires the presence of a tubulin dimer to accelerate release of ADP and phosphate.
70464	alphav-beta3 integrin-collagen alpha3(VI) complex	C	A protein complex that consists of an alphav-beta3 integrin complex bound to the alpha3 chain of type VI collagen; the integrin binds most strongly to unfolded collagen.
70465	alpha1-beta1 integrin-alpha3(VI) complex	C	A protein complex that consists of an alpha1-beta1 integrin complex bound to a type VI collagen triple helix containing an alpha3(VI) chain.
70466	alpha2-beta1 integrin-alpha3(VI) complex	C	A protein complex that consists of an alpha2-beta1 integrin complex bound to a type VI collagen triple helix containing an alpha3(VI) chain.
70467	RC-1 DNA recombination complex	C	A protein complex that contains DNA ligase III, DNA polymerase epsilon, a 5'-3' exonuclease, and the SMC1 and SMC2 proteins, and is involved in recombinational repair of deletions and gaps in DNA.
70468	dentin secretion	P	The regulated release by odontoblasts of the extracellular matrix constituents, including collagen, that form the basis of dentin.
70469	respiratory chain	C	The protein complexes that form the electron transport system (the respiratory chain), associated with a cell membrane, usually the plasma membrane (in prokaryotes) or the inner mitochondrial membrane (on eukaryotes). The respiratory chain complexes transfer electrons from an electron donor to an electron acceptor and are associated with a proton pump to create a transmembrane electrochemical gradient.
70470	plasma membrane respiratory chain	C	A respiratory chain located in the plasma membrane of a cell; made up of the protein complexes that form the electron transport system (the respiratory chain), associated with the plasma membrane. The respiratory chain complexes transfer electrons from an electron donor to an electron acceptor and are associated with a proton pump to create a transmembrane electrochemical gradient.
70471	uterine smooth muscle contraction	P	A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry. This process occurs in the uterus. Force generation involves a chemo-mechanical energy conversion step that is carried out by the actin/myosin complex activity, which generates force through ATP hydrolysis. The uterus is a muscular organ of the female mammal for containing and usually for nourishing the young during development prior to birth.
70472	regulation of uterine smooth muscle contraction	P	Any process that modulates the frequency, rate or extent of uterine smooth muscle contraction.
70473	negative regulation of uterine smooth muscle contraction	P	Any process that decreases the frequency, rate or extent of uterine smooth muscle contraction.
70474	positive regulation of uterine smooth muscle contraction	P	Any process that increases the frequency, rate or extent of uterine smooth muscle contraction.
70475	rRNA base methylation	P	The addition of a methyl group to an atom in the nucleoside base portion of a nucleotide residue in an rRNA molecule.
70476	rRNA (guanine-N7)-methylation	P	The addition of a methyl group to the N7 atom in the base portion of a guanine nucleotide residue in an rRNA molecule.
70477	endospore core	C	An intracellular part that represents the innermost portion of an endospore; the endospore core is dehydrated, enriched in dipicolinic acid and divalent cations, and metabolically inactive.
70478	nuclear-transcribed mRNA catabolic process, 3'-5' exonucleolytic nonsense-mediated decay	P	The chemical reactions and pathways resulting in the breakdown of the nuclear-transcribed mRNA transcript body of an mRNA in which an amino-acid codon has changed to a nonsense codon; occurs when the 3' end is not protected by a 3'-poly(A) tail; degradation proceeds in the 3' to 5' direction.
70479	nuclear-transcribed mRNA catabolic process, 5'-3' exonucleolytic nonsense-mediated decay	P	The chemical reactions and pathways resulting in the breakdown of the nuclear-transcribed mRNA transcript body of an mRNA in which an amino-acid codon has changed to a nonsense codon; occurs when the 5' end is not protected by a 5'-cap; degradation proceeds in the 5' to 3' direction.
70480	exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-independent decay	P	The chemical reactions and pathways resulting in the breakdown of the transcript body of a nuclear-transcribed mRNA that occurs independent of deadenylation, but requires decapping followed by transcript decay.
70481	nuclear-transcribed mRNA catabolic process, non-stop decay	P	The chemical reactions and pathways resulting in the breakdown of the transcript body of a nuclear-transcribed mRNA that is lacking a stop codon.
70482	response to oxygen levels	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of oxygen.
70483	detection of hypoxia	P	The series of events in which a stimulus indicating lowered oxygen tension is received by a cell and converted into a molecular signal. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level.
70484	dehydro-D-arabinono-1,4-lactone metabolic process	P	The chemical reactions and pathways involving dehydro-D-arabinono-1,4-lactone, the gamma-lactone (5R)-3,4-dihydroxy-5-(hydroxymethyl)furan-2(5H)-one.
70485	dehydro-D-arabinono-1,4-lactone biosynthetic process	P	The chemical reactions and pathways resulting in the formation of dehydro-D-arabinono-1,4-lactone, the gamma-lactone (5R)-3,4-dihydroxy-5-(hydroxymethyl)furan-2(5H)-one.
70486	leukocyte aggregation	P	The adhesion of one leukocyte to one or more other leukocytes via adhesion molecules.
70487	monocyte aggregation	P	The adhesion of one monocyte to one or more other monocytes via adhesion molecules.
70488	neutrophil aggregation	P	The adhesion of one neutrophil to one or more other neutrophils via adhesion molecules.
70489	T cell aggregation	P	The adhesion of one T cell to one or more other T cells via adhesion molecules.
70490	protein pupylation	P	The process in which a Pup protein is conjugated to a target protein via an isopeptide bond between the carboxyl terminus of Pup and the epsilon-amino group of a lysine residue of the target protein.
70491	repressing transcription factor binding	F	Interacting selectively and non-covalently with a transcription repressor, any protein whose activity is required to prevent or downregulate transcription.
70492	oligosaccharide binding	F	Interacting selectively and non-covalently with any oligosaccharide, a molecule with between two and (about) 20 monosaccharide residues connected by glycosidic linkages.
70493	thrombin-activated receptor signaling pathway	P	The series of molecular signals generated as a consequence of a thrombin-activated receptor binding to one of its physiological ligands.
70494	regulation of thrombin-activated receptor signaling pathway	P	Any process that modulates the frequency, rate or extent of a thrombin-activated receptor signaling pathway activity. A thrombin receptor signaling pathway is the series of molecular signals generated as a consequence of a thrombin-activated receptor binding to one of its physiological ligands.
70495	negative regulation of thrombin-activated receptor signaling pathway	P	Any process that stops, prevents, or reduces the frequency, rate or extent of thrombin-activated receptor protein signaling pathway activity. A thrombin receptor signaling pathway is the series of molecular signals generated as a consequence of a thrombin-activated receptor binding to one of its physiological ligands.
70496	positive regulation of thrombin-activated receptor signaling pathway	P	Any process that activates or increases the frequency, rate or extent of thrombin-activated receptor protein signaling pathway activity. A thrombin receptor signaling pathway is the series of molecular signals generated as a consequence of a thrombin-activated receptor binding to one of its physiological ligands.
70497	6-carboxy-5,6,7,8-tetrahydropterin synthase activity	F	Catalysis of the reaction: 7,8-dihydroneopterin triphosphate + H2O = 6-carboxy-5,6,7,8-tetrahydropterin + triphosphate + acetaldehyde + 2 H+.
70498	interleukin-1-mediated signaling pathway	P	A series of molecular signals initiated by the binding of interleukin-1 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.
70499	exosporium assembly	P	A process that is carried out at the cellular level which results in the formation of an exosporium, the outermost layer of a bacterial endospore.
70500	poly-gamma-glutamate metabolic process	P	The chemical reactions and pathways involving poly-gamma-glutamate, a polymer of D- and/or L-glutamic acid residues linked by gamma-peptidyl bonds.
70501	poly-gamma-glutamate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of poly-gamma-glutamate, a polymer of D- and/or L-glutamic acid residues linked by gamma-peptidyl bonds.
70502	capsule poly-gamma-glutamate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of poly-gamma-glutamate, a polymer of D- and/or L-glutamic acid residues linked by gamma-peptidyl bonds, that forms all or part of a bacterial capsule.
70503	selenium-containing prosthetic group metabolic process	P	The chemical reactions and pathways involving a prosthetic group that contains selenium, as in the selenium-dependent molybdenum hydroxylases. The selenium atom in the prosthetic group is required for enzymatic function but is labile to a variety of treatments.
70504	selenium-containing prosthetic group biosynthetic process	P	The chemical reactions and pathways resulting in the formation of a prosthetic group that contains selenium, as in the selenium-dependent molybdenum hydroxylases. The selenium atom in the prosthetic group is required for enzymatic function but is labile to a variety of treatments.
70505	pollen coat	C	A layer of extracellular matrix deposited onto the surface of the pollen wall upon disintegration of the tapetal layer of the anther wall in the late stages of pollen development. The composition of this material is highly heterogeneous and includes waxes, lipid droplets, small aromatic molecules, and proteins. The pollen coat is proposed to have many functions, such as holding pollen in the anther until dispersal, facilitation of pollen dispersal, protection of pollen from water loss and UV radiation, and facilitation of adhesion of pollen to the stigma.
70506	high-density lipoprotein particle receptor activity	F	Combining with a high-density lipoprotein particle and delivering the high-density lipoprotein into the cell via endocytosis.
70507	regulation of microtubule cytoskeleton organization	P	Any process that modulates the frequency, rate or extent of the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins.
70508	cholesterol import	P	The directed movement of cholesterol into a cell or organelle.
70509	calcium ion import	P	The directed movement of calcium ions into a cell or organelle.
70510	regulation of histone H4-K20 methylation	P	Any process that modulates the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 20 of histone H4.
70511	negative regulation of histone H4-K20 methylation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 20 of histone H4.
70512	positive regulation of histone H4-K20 methylation	P	Any process that activates or increases the frequency, rate or extent of the covalent addition of a methyl group to the lysine at position 20 of histone H4.
70513	death domain binding	F	Interacting selectively and non-covalently with a death domain of a protein. The death domain (DD) is a homotypic protein interaction module composed of a bundle of six alpha-helices. DD bind each other forming oligomers. Some DD-containing proteins are involved in the regulation of apoptosis and inflammation through their activation of caspases and NF-kappaB.
70514	SRF-myogenin-E12 complex	C	A transcription factor complex that contains the serum response factor (SRF) and the basic helix-loop-helix proteins myogenin and E12, and is involved in activating transcription of muscle-specific genes.
70515	alphaIIb-beta3 integrin-talin complex	C	A protein complex that consists of an alphaIIb-beta3 integrin complex bound to talin.
70516	CAK-ERCC2 complex	C	A protein complex formed by the association of the cyclin-dependent protein kinase activating kinase (CAK) holoenzyme complex with ERCC2.
70517	DNA replication factor C core complex	C	A protein complex containing three of the five subunits of eukaryotic replication factor C, those corresponding to human p40, p38, and p37.
70518	alpha4-beta1 integrin-CD53 complex	C	A protein complex that consists of an alpha4-beta1 integrin complex bound to membrane protein CD53, a member of the tetraspan family.
70519	alpha4-beta1 integrin-CD63 complex	C	A protein complex that consists of an alpha4-beta1 integrin complex bound to membrane protein CD63, a member of the tetraspan family.
70520	alpha4-beta1 integrin-CD81 complex	C	A protein complex that consists of an alpha4-beta1 integrin complex bound to membrane protein CD81, a member of the tetraspan family.
70521	alpha4-beta1 integrin-CD82 complex	C	A protein complex that consists of an alpha4-beta1 integrin complex bound to membrane protein CD82, a member of the tetraspan family.
70522	ERCC4-ERCC1 complex	C	A heterodimeric nucleotide-excision repair complex that has endonuclease activity specific for bubble structures characteristic of certain DNA lesions. The subunits are known as XPF/ERCC4 and ERCC1 in mammals, and Rad1p and Rad10p in S. cerevisiae.
70523	11-beta-hydroxysteroid dehydrogenase (NAD+) activity	F	Catalysis of the reaction: an 11-beta-hydroxysteroid + NAD+ = an 11-oxosteroid + NADH + H+.
70524	11-beta-hydroxysteroid dehydrogenase (NADP+) activity	F	Catalysis of the reaction: an 11-beta-hydroxysteroid + NADP+ = an 11-oxosteroid + NADPH + H+.
70525	tRNA threonylcarbamoyladenosine metabolic process	P	The chemical reactions and pathways involving tRNA threonylcarbamoyladenosine, a modified nucleoside found in some tRNA molecules.
70527	platelet aggregation	P	The adhesion of one platelet to one or more other platelets via adhesion molecules.
70528	protein kinase C signaling	P	A series of reactions, mediated by the intracellular serine/threonine kinase protein kinase C, which occurs as a result of a single trigger reaction or compound.
70529	L-tryptophan aminotransferase activity	F	Catalysis of the transfer of an amino group from L-tryptophan to an acceptor, usually a 2-oxo acid.
70530	K63-linked polyubiquitin binding	F	Interacting selectively and non-covalently and non-covalently with a polymer of ubiquitin formed by linkages between lysine residues at position 63 of the ubiquitin monomers.
70531	BRCA1-A complex	C	A protein complex that contains the BRCA1-BARD1 heterodimer, RAP80/UIMC1, BRCC3/BRCC36, BRE/BRCC45, FAM175A/CCDC98/Abraxas and MERIT40/NBA1, and specifically recognizes and binds K63-linked polyubiquitin chains present on histone H2A and H2AX at DNA damage sites.
70532	BRCA1-B complex	C	A protein complex that contains the BRCA1-BARD1 heterodimer, BACH1 and TopBP1, and binds to DNA during S phase at DNA damage sites.
70533	BRCA1-C complex	C	A protein complex that contains the BRCA1-BARD1 heterodimer, CtIP and Mre11/Rad50/NBS1 (M/R/N) complex, and binds to DNA at DNA damage sites. BRCA1-C binding ta damaged DNA is required for DNA damage-induced Chk1 phosphorylation and the G2/M transition checkpoint.
70534	protein K63-linked ubiquitination	P	A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 63 of the ubiquitin monomers, is added to a protein. K63-linked ubiquitination does not target the substrate protein for degradation, but is involved in several pathways, notably as a signal to promote error-free DNA postreplication repair.
70535	histone H2A K63-linked ubiquitination	P	A histone ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 63 of the ubiquitin monomers, is added to a lysine residue in histone H2A or the variant H2AX.
70536	protein K63-linked deubiquitination	P	A protein deubiquitination process in which a K63-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 63 of the ubiquitin monomers, is removed from a protein.
70537	histone H2A K63-linked deubiquitination	P	A protein deubiquitination process in which a K63-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 63 of the ubiquitin monomers, is removed from a lysine residue in histone H2A or the variant H2AX.
70538	oleic acid binding	F	Interacting selectively and non-covalently with oleic acid, the 18-carbon monounsaturated fatty acid (9Z)-octadec-9-enoic acid.
70539	linoleic acid binding	F	Interacting selectively and non-covalently with linoleic acid, the 18-carbon unsaturated fatty acid (9Z,12Z)-octadeca-9,12-dienoic acid.
70540	stearic acid binding	F	Interacting selectively and non-covalently with stearic acid, the 18-carbon saturated fatty acid octadecanoic acid.
70541	response to platinum ion	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a platinum stimulus.
70542	response to fatty acid	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fatty acid stimulus.
70543	response to linoleic acid	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a linoleic acid stimulus.
70544	histone H3-K36 demethylation	P	The modification of histone H3 by the removal of a methyl group from lysine at position 36 of the histone.
70545	PeBoW complex	C	A protein complex that is involved in coordinating ribosome biogenesis with cell cycle progression. In human, it is composed of Pes1, Bop1, and WDR12; in Saccharomyces the proteins are known as Nop7p, Erb1 and Ytm1 respectively.
70546	L-phenylalanine aminotransferase activity	F	Catalysis of the transfer of an amino group from L-phenylalanine to an acceptor, usually a 2-oxo acid.
70547	L-tyrosine aminotransferase activity	F	Catalysis of the transfer of an amino group from L-tyrosine to an acceptor, usually a 2-oxo acid.
70548	L-glutamine aminotransferase activity	F	Catalysis of the transfer of an amino group from L-glutamine to an acceptor, usually a 2-oxo acid.
70549	negative regulation of translation involved in RNA interference	P	A process of negative regulation of translation that is mediated by the association of small interfering RNAs (siRNAs) with a cognate target mRNA.
70550	rDNA condensation	P	The process in which the chromatin structure of the rDNA repeats is compacted. In S. cerevisiae, condensation and resolution of the rDNA occurs during anaphase.
70551	endoribonuclease activity, cleaving siRNA-paired mRNA	F	Catalysis of the endonucleolytic cleavage of the mRNA in a double-stranded RNA molecule formed by the base pairing of an mRNA with an siRNA, yielding 5'-phosphomonoesters.
70552	BRISC complex	C	A protein complex that contains the FAM175B/ABRO1, BRCC3/BRCC36, BRE/BRCC45 and MERIT40/NBA1 proteins, and specifically cleaves K63-linked polyubiquitin chains.
70553	nicotinic acid receptor activity	F	Combining with nicotinic acid to initiate a change in cell activity.
70554	synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex	C	A SNARE complex that contains synaptobrevin 2 (VAMP2), SNAP-25, syntaxin 3, and a complexin (or orthologs thereof).
70555	response to interleukin-1	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-1 stimulus.
70556	TAF4B-containing transcription factor TFIID complex	C	A transcription factor TFIID complex that contains the TBP-associated factor TAF4B (also known as TAFII105 in human), a cell-type-specific variant of TAF4.
70557	PCNA-p21 complex	C	A protein complex that contains the cyclin-dependent protein kinase inhibitor p21WAF1/CIP1 bound to PCNA; formation of the complex inhibits DNA replication.
70558	alphaM-beta2 integrin-CD63 complex	C	A protein complex that consists of an alphaM-beta2 integrin complex bound to membrane protein CD63, a member of the tetraspan family.
70559	lysosomal multienzyme complex	C	A protein complex found in the lysosome that contains beta-galactosidase, cathepsin A, alpha-neuraminidase and N-acetylgalactosamine-6-sulfate sulfatase, and is involved in glycosaminoglycan catabolism.
70560	protein secretion by platelet	P	The regulated release of proteins by a platelet or group of platelets.
70561	vitamin D receptor signaling pathway	P	The series of molecular signals generated as a consequence of a vitamin D receptor binding to one of its physiological ligands.
70562	regulation of vitamin D receptor signaling pathway	P	Any process that modulates the frequency, rate or extent of vitamin D receptor signaling pathway activity.
70563	negative regulation of vitamin D receptor signaling pathway	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the vitamin D receptor signaling pathway activity.
70564	positive regulation of vitamin D receptor signaling pathway	P	Any process that activates or increases the frequency, rate or extent of vitamin D receptor signaling pathway activity.
70565	telomere-telomerase complex	C	A complex of DNA and protein located at the end of a linear chromosome that enables replication of the telomeric repeat sequences at the end of a linear chromosome.
70566	adenylyltransferase activity	F	Catalysis of the transfer of an adenylyl group to an acceptor.
70567	cytidylyltransferase activity	F	Catalysis of the transfer of a cytidylyl group to an acceptor.
70568	guanylyltransferase activity	F	Catalysis of the transfer of a guanylyl group to an acceptor.
70569	uridylyltransferase activity	F	Catalysis of the transfer of an uridylyl group to an acceptor.
70570	regulation of neuron projection regeneration	P	Any process that modulates the rate, frequency or extent of neuron projection regeneration, the regrowth of neuronal processes such as axons or dendrites following their loss or damage.
70571	negative regulation of neuron projection regeneration	P	Any process that stops, prevents, or reduces the frequency, rate or extent of neuron projection regeneration, the regrowth of neuronal processes such as axons or dendrites following their loss or damage.
70572	positive regulation of neuron projection regeneration	P	Any process that activates or increases the frequency, rate or extent of neuron projection regeneration, the regrowth of neuronal processes such as axons or dendrites following their loss or damage.
70573	metallodipeptidase activity	F	Catalysis of the hydrolysis of a dipeptide by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions.
70574	cadmium ion transmembrane transport	P	A process in which a cadmium ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.
70575	peptide mating pheromone maturation involved in pheromone-induced unidirectional conjugation	P	The formation of a mature peptide mating pheromone by proteolysis and/or modification of a peptide precursor, occurring in the context of pheromone-induced unidirectional conjugation.
70576	vitamin D 24-hydroxylase activity	F	Catalysis of the hydroxylation of C-24 of any form of vitamin D.
70577	lysine-acetylated histone binding	F	Interacting selectively and non-covalently with a histone in which a lysine residue has been modified by acetylation.
70578	RISC-loading complex	C	A trimeric ribonucleoprotein complex that and is required for the formation of a mature RNA induced silencing complex (RISC). In humans the complex is composed of the endonuclease Dicer (DICER1) and TRBP (TARBP2) in association with the Argonaute protein Ago2 (EIF2C2/AGO2). Within the complex, Dicer and TRBP are required to process precursor miRNAs (pre-miRNAs) to mature miRNAs and then load them onto Ago2. Ago2 bound to the mature miRNA constitutes the minimal RISC and may subsequently dissociate from Dicer and TRBP. This complex has endoribonuclease activity.
70579	methylcytosine dioxygenase activity	F	Catalysis of the reaction: methylcytosine + 2-oxoglutarate + O2 = 5-hydroxymethylcytosine + succinate + CO2.
70580	base J metabolic process	P	The chemical reactions and pathways involving base J (beta-D-glucosyl-hydroxymethyluracil), a hypermodified thymidine residue found in the genome of kinetoplastid parasites. This modified base is localized primarily to repetitive DNA, namely the telomeres, and is implicated in the regulation of antigenic variation. The base is synthesized in a two-step pathway. Initially, a thymidine residue in DNA is hydroxylated by a thymidine hydroxylase (TH) to form the intermediate hydroxymethyluracil, which is then glucosylated to form base J.
70581	rolling circle DNA replication	P	A DNA-dependent DNA replication process in which a single-stranded DNA molecule is synthesized from a circular duplex template. Replication typically does not cease when one circumference has been replicated, but continues around the circumference several more times, producing a long single strand comprising multimers of the replicon.
70582	theta DNA replication	P	A DNA-dependent DNA replication process in which a double-stranded DNA molecule is synthesized from a circular duplex template.
70583	spore membrane bending pathway	P	The process in which a bending force is generated in the prospore membrane to form the characteristic curved shape of the prospore.
70584	mitochondrion morphogenesis	P	The process in which the anatomical structures of a mitochondrion are generated and organized.
70585	protein localization to mitochondrion	P	A process in which a protein is transported to, or maintained in, a location within the mitochondrion.
70586	cell-cell adhesion involved in gastrulation	P	The attachment of one cell to another cell affecting gastrulation.
70587	regulation of cell-cell adhesion involved in gastrulation	P	Any process that modulates the frequency, rate, or extent of attachment of a cell to another cell affecting gastrulation.
70588	calcium ion transmembrane transport	P	A process in which a calcium ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.
70589	cellular component macromolecule biosynthetic process	P	The chemical reactions and pathways resulting in the formation of a macromolecule that is destined to form part of a specific cellular component.
70590	spore wall biogenesis	P	A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a spore wall. A spore wall is the specialized cell wall lying outside the cell membrane of a spore.
70591	ascospore wall biogenesis	P	A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of an ascospore wall.
70592	cell wall polysaccharide biosynthetic process	P	The chemical reactions and pathways resulting in the formation of a polysaccharide destined to form part of a cell wall.
70593	dendrite self-avoidance	P	The process in which dendrites recognize and avoid contact with sister dendrites from the same cell.
70594	juvenile hormone response element binding	F	Interacting selectively and non-covalently with the juvenile hormone response element (JHRE), a conserved sequence found in the promoters of genes whose expression is regulated in response to juvenile hormone.
70595	(1->3)-alpha-glucan metabolic process	P	The chemical reactions and pathways involving (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds.
70596	(1->3)-alpha-glucan biosynthetic process	P	The chemical reactions and pathways resulting in the formation of (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds.
70597	cell wall (1->3)-alpha-glucan metabolic process	P	The chemical reactions and pathways involving (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds, found in the walls of cells.
70598	cell wall (1->3)-alpha-glucan biosynthetic process	P	The chemical reactions and pathways resulting in the formation of (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-glucosidic bonds, found in the walls of cells.
70599	fungal-type cell wall (1->3)-alpha-glucan metabolic process	P	The chemical reactions and pathways involving (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds, found in the walls of ascospores.
70600	fungal-type cell wall (1->3)-alpha-glucan biosynthetic process	P	The chemical reactions and pathways resulting in the formation of (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds, found in fungal-type cell walls, including those of ascospores.
70601	centromeric sister chromatid cohesion	P	The cell cycle process in which the sister chromatids of a replicated chromosome are joined along the length of the centromeric region of the chromosome.
70602	regulation of centromeric sister chromatid cohesion	P	Any process that modulates the frequency, rate or extent of sister chromatid cohesion in the centromeric region of a chromosome.
70603	SWI/SNF superfamily-type complex	C	A protein complex that contains an ortholog of the Saccharomyces ATPase Swi2/Snf2 as one of the core components and mediates assembly of nucleosomes, changes to the spacing or structure of nucleosomes, or some combination of those activities in a manner that requires ATP.
70604	PBAF complex	C	A SWI/SNF-type complex that contains the ATPase product of the mammalian BAF180 gene.
70605	regulation of (1->3)-alpha-glucan metabolic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds.
70606	regulation of (1->3)-alpha-glucan biosynthetic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds.
70607	regulation of cell wall (1->3)-alpha-glucan metabolic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds, found in the walls of cells.
70608	regulation of cell wall (1->3)-alpha-glucan biosynthetic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds, found in the walls of cells.
70609	regulation of fungal-type cell wall (1->3)-alpha-glucan metabolic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving (1->3)-alpha-D-glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds, found in the walls of ascospores.
70610	regulation of fungal-type cell wall (1->3)-alpha-glucan biosynthetic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of (1->3)-alpha glucans, compounds composed of glucose residues linked by (1->3)-alpha-D-glucosidic bonds, found in fungal-type cell walls, including those of ascospores.
70611	histone methyltransferase activity (H3-R2 specific)	F	Catalysis of the reaction: S-adenosyl-L-methionine + (histone H3)-arginine (position 2) = S-adenosyl-L-homocysteine + (histone H3)-N-methyl-arginine (position 2). This reaction is the addition of a methyl group to arginine at position 2 of histone H3.
70612	histone methyltransferase activity (H2A-R3 specific)	F	Catalysis of the reaction: S-adenosyl-L-methionine + (histone H2A)-arginine (position 3) = S-adenosyl-L-homocysteine + (histone H2A)-N-methyl-arginine (position 3). This reaction is the addition of a methyl group to arginine at position 3 of histone H2A.
70613	regulation of protein processing	P	Any process that modulates the frequency, rate or extent of protein processing, any protein maturation process achieved by the cleavage of a peptide bond or bonds within a protein.
70614	tungstate ion transport	P	The directed movement of tungstate (WO4 2-) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Tungstate is a bivalent oxoanion of tungsten.
70615	nucleosome-dependent ATPase activity	F	Catalysis of the reaction: ATP + H2O = ADP + phosphate. This reaction requires the presence of one or more nucleosomes.
70616	regulation of thiamine diphosphate biosynthetic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of thiamine diphosphate.
70617	negative regulation of thiamine diphosphate biosynthetic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of thiamine diphosphate.
70618	Grb2-Sos complex	C	A protein complex that contains Grb2 and the guanine nucleotide exchange factor Sos (or an ortholog thereof, such as mSos1), and is involved in linking EGFR activation to the p21-Ras pathway.
70619	Shc-Grb2-Sos complex	C	A protein complex that contains Grb2, the adaptor protein Shc and the guanine nucleotide exchange factor Sos (or an ortholog thereof, such as mSos1), and is involved in linking EGFR activation to the p21-Ras pathway.
70620	EGFR-Grb2-Sos complex	C	A protein complex that contains the epidermal growth factor receptor (EGFR), Grb2 and the guanine nucleotide exchange factor Sos (or an ortholog thereof, such as mSos1), and is involved in linking EGFR activation to the p21-Ras pathway.
70621	EGFR-Shc-Grb2-Sos complex	C	A protein complex that contains the epidermal growth factor receptor (EGFR), Grb2, the adaptor protein SHC and the guanine nucleotide exchange factor Sos (or an ortholog thereof, such as mSos1), and is involved in linking EGFR activation to the p21-Ras pathway.
70622	UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase complex	C	A protein complex that possesses UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity; the bovine complex contains disulfide-linked homodimers of 166- and 51-kDa subunits and two identical, noncovalently associated 56-kDa subunits.
70623	regulation of thiamine biosynthetic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of thiamine.
70624	negative regulation of thiamine biosynthetic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of thiamine.
70625	zymogen granule exocytosis	P	The release of intracellular molecules contained within the zymogen granule by fusion of the granule with the plasma membrane of the oocyte, requiring calcium ions.
70626	(S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate AMP-lyase (fumarate-forming) activity	F	Catalysis of the reaction: (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate = fumarate + 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide.
70627	ferrous iron import	P	The directed movement of ferrous iron (Fe(II) or Fe2+) ions across a membrane into a cell or organelle.
70628	proteasome binding	F	Interacting selectively and non-covalently with a proteasome, a large multisubunit protein complex that catalyzes protein degradation.
70629	(1->4)-alpha-glucan metabolic process	P	The chemical reactions and pathways involving (1->4)-alpha-glucans, compounds composed of glucose residues linked by (1->4)-alpha-D-glucosidic bonds.
70630	(1->4)-alpha-glucan biosynthetic process	P	The chemical reactions and pathways resulting in the formation of (1->4)-alpha-glucans, compounds composed of glucose residues linked by (1->4)-alpha-D-glucosidic bonds.
70631	spindle pole body localization	P	Any process in which a spindle pole body is transported to, or maintained in, a specific location. A spindle pole body is a type of microtubule organizing center found in fungal cells.
70632	establishment of spindle pole body localization	P	Any process in which a spindle pole body is transported to a specific location. A spindle pole body is a type of microtubule organizing center found in fungal cells.
70633	transepithelial transport	P	The directed movement of a substance from one side of an epithelium to the other.
70634	transepithelial ammonium transport	P	The directed movement of ammonium ions from one side of an epithelium to the other.
70635	nicotinamide riboside hydrolase activity	F	Catalysis of the reaction: nicotinamide riboside + H2O = nicotinamide + D-ribose.
70636	nicotinic acid riboside hydrolase activity	F	Catalysis of the reaction: nicotinic acid riboside + H2O = nicotinic acid + D-ribose.
70637	pyridine nucleoside metabolic process	P	The chemical reactions and pathways involving any pyridine nucleoside, a nucleoside in which a pyridine base covalently bonded to a sugar, usually ribose.
70638	pyridine nucleoside catabolic process	P	The chemical reactions and pathways resulting in the breakdown of any pyridine nucleoside, a nucleoside in which a pyridine base covalently bonded to a sugar, usually ribose.
70639	vitamin D2 metabolic process	P	The chemical reactions and pathways involving vitamin D2, (3S,5Z,7E,22E)-9,10-secoergosta-5,7,10(19),22-tetraen-3-ol.
70640	vitamin D3 metabolic process	P	The chemical reactions and pathways involving vitamin D3, (3S,5Z,7E)-9,10-secocholesta-5,7,10(19)-trien-3-ol.
70641	vitamin D4 metabolic process	P	The chemical reactions and pathways involving vitamin D4, (3S,5Z,7E)-9,10-secoergosta-5,7,10(19)-trien-3-ol.
70642	vitamin D5 metabolic process	P	The chemical reactions and pathways involving vitamin D5, (1S,3Z)-3-[(2E)-2-[(1R,3aS,7aR)-1-[(1R,4S)-4-ethyl-1,5-dimethylhexyl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylene-1-cyclohexanol.
70643	vitamin D 25-hydroxylase activity	F	Catalysis of the hydroxylation of C-25 of any form of vitamin D.
70644	vitamin D response element binding	F	Interacting selectively and non-covalently with the vitamin D response element (VDRE), a short sequence with dyad symmetry found in the promoters of some of the cellular immediate-early genes, regulated by serum.
70645	Ubisch body	C	A small, granular structure that is found in the extracellular matrix of cell of the secretory tapetal layer that surrounds developing pollen grains. Ubisch bodies have a sporopollenin coat, are attached to the peritapetal wall, and may play a role in pollen development.
70646	protein modification by small protein removal	P	A protein modification process in which one or more covalently attached groups of a small protein, such as ubiquitin or a ubiquitin-like protein, are removed from a target protein.
70647	protein modification by small protein conjugation or removal	P	A protein modification process in which one or more groups of a small protein, such as ubiquitin or a ubiquitin-like protein, are covalently attached to or removed from a target protein.
70648	formin-nucleated actin cable	C	An actin filament bundle that consists of short filaments organized into bundles of uniform polarity, and is nucleated by formins. In fungal cells, myosin motors transport cargo along actin cables toward sites of polarized cell growth; actin cables may play a similar role in pollen tube growth.
70649	formin-nucleated actin cable assembly	P	The aggregation, arrangement and bonding together of a set of components to form a formin-nucleated actin cable. A formin-nucleated actin cable is an actin filament bundle that consists of short filaments organized into bundles of uniform polarity, and is nucleated by formins.
70650	actin filament bundle distribution	P	Any cellular process that establishes the spatial arrangement of actin filament bundles within the cell.
70651	nonfunctional rRNA decay	P	An rRNA catabolic process that results in the targeted detection and degradation of aberrant rRNAs contained within translationally defective ribosomes, thereby acting as a quality-control system.
70652	HAUS complex	C	A protein complex that localizes to interphase centrosomes and to mitotic spindle tubules and regulates mitotic spindle assembly and centrosome integrity; in human, the complex consists of eight subunits, some of which are homologous to subunits of the Drosophila Augmin complex.
70653	high-density lipoprotein particle receptor binding	F	Interacting selectively and non-covalently with a high-density lipoprotein receptor.
70654	sensory epithelium regeneration	P	The regrowth of a sensory epithelium following its loss or destruction.
70655	mechanosensory epithelium regeneration	P	The regrowth of lost or destroyed mechanosensory epithelia.
70656	mechanoreceptor differentiation involved in mechanosensory epithelium regeneration	P	Differentiation of new mechanoreceptors to replace those lost or destroyed by injury.
70657	neuromast regeneration	P	The regrowth of a neuromast following its loss or destruction.
70658	neuromast hair cell differentiation involved in neuromast regeneration	P	Differentiation of new neuromast sensory hair cells to replace those lost or destroyed by injury.
70659	inner ear sensory epithelium regeneration	P	The regrowth of lost or destroyed inner ear sensory epithelia.
70660	inner ear receptor cell differentiation involved in inner ear sensory epithelium regeneration	P	Differentiation of new inner ear sensory hair cells to replace those lost or destroyed by injury.
70661	leukocyte proliferation	P	The expansion of a leukocyte population by cell division.
70662	mast cell proliferation	P	The expansion of a mast cell population by cell division.
70663	regulation of leukocyte proliferation	P	Any process that modulates the frequency, rate or extent of leukocyte proliferation.
70664	negative regulation of leukocyte proliferation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of leukocyte proliferation.
70665	positive regulation of leukocyte proliferation	P	Any process that activates or increases the frequency, rate or extent of leukocyte proliferation.
70666	regulation of mast cell proliferation	P	Any process that modulates the frequency, rate or extent of mast cell proliferation.
70667	negative regulation of mast cell proliferation	P	Any process that stops, prevents or reduces the rate or extent of mast cell proliferation.
70668	positive regulation of mast cell proliferation	P	Any process that activates or increases the rate or extent of mast cell proliferation.
70669	response to interleukin-2	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-2 stimulus.
70670	response to interleukin-4	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-4 stimulus.
70671	response to interleukin-12	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-12 stimulus.
70672	response to interleukin-15	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-15 stimulus.
70673	response to interleukin-18	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-18 stimulus.
70674	hypoxanthine dehydrogenase activity	F	Catalysis of the reaction: hypoxanthine + NAD+ + H2O = xanthine + NADH + H+.
70675	hypoxanthine oxidase activity	F	Catalysis of the reaction: hypoxanthine + H2O + O2 = xanthine + H2O2.
70676	intralumenal vesicle formation	P	The invagination of the endosome membrane and resulting formation of a vesicle within the lumen of the endosome.
70677	rRNA (cytosine-2'-O-)-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing 2'-O-methylcytosine.
70678	preprotein binding	F	Interacting selectively and non-covalently with a preprotein, the unprocessed form of a protein destined to undergo co- or post-translational processing.
70679	inositol 1,4,5 trisphosphate binding	F	Interacting selectively and non-covalently with inositol 1,4,5 trisphosphate.
70680	asparaginyl-tRNAAsn biosynthesis via transamidation	P	A tRNA aminoacylation process in which asparaginyl-tRNAAsn is formed by a tRNA-dependent two-step pathway. In the first step a non-discriminating aspartyl-tRNA synthetase generates the misacylated L-aspartyl-tRNAAsn species, and in the second step it is amidated to the correctly charged L-asparaginyl-tRNAAsn by the heterotrimeric aspartyl-tRNAAsn amidotransferase.
70681	glutaminyl-tRNAGln biosynthesis via transamidation	P	A tRNA aminoacylation process in which glutaminyl-tRNAGln is formed by a tRNA-dependent two-step pathway. In the first step a non-discriminating glutamyl-tRNAGlx synthetase generates the misacylated L-glutamyl-tRNAGln species, and in the second step it is amidated to the correctly charged L-glutaminyl-tRNAGln by a glutamyl-tRNAGln amidotransferase.
70682	proteasome regulatory particle assembly	P	The aggregation, arrangement and bonding together of a mature, active proteasome regulatory particle complex.
70684	seminal clot liquefaction	P	The reproductive process in which coagulated semen becomes liquid following ejaculation, allowing the progressive release of motile spermatozoa.
70685	macropinocytic cup	C	A cell projection that forms at the site of macropinocytosis, a form of endocytosis that results in the uptake of relatively large amounts of extracellular fluid. The macropinocytic cup membrane selectively excludes certain proteins, such as H36 or PM4C4 in Dictyostelium, and the underlying cytoskeleton is enriched in F-actin and coronin.
70686	macropinocytic cup membrane	C	The portion of the plasma membrane surrounding a macropinocytic cup.
70687	macropinocytic cup cytoskeleton	C	The part of the cortical actin cytoskeleton that forms part of a macropinocytic cup.
70688	MLL5-L complex	C	A protein complex that can methylate lysine-4 of histone H3 and plays an essential role in retinoic-acid-induced granulopoiesis. MLL5 is the catalytic methyltransferase subunit, and the complex also contains serine/threonine kinase 38 (STK38), protein phosphatase 1 catalytic subunits, the host cell factor-1 N-terminal subunit, beta-actin, and O-GlcNAc transferase; the human genes encoding the subunits are MLL5, STK38, PPP1CA, PPP1CB, PPP1CC, HCFC1, ACTB and OGT, respectively.
70689	L-threonine catabolic process to propionate	P	The chemical reactions and pathways resulting in the breakdown of L-threonine (the L-enantiomer of 2-amino-3-hydroxybutyric acid) to form the compound propionate.
70690	L-threonine catabolic process to acetyl-CoA	P	The chemical reactions and pathways resulting in the breakdown of L-threonine (the L-enantiomer of 2-amino-3-hydroxybutyric acid) into glycine and acetaldehyde, with acetaldehyde being subsequently converted to acetyl-CoA.
70691	P-TEFb complex	C	A dimeric positive transcription elongation factor complex b that comprises a cyclin-dependent kinase containing the catalytic subunit, Cdk9, and a regulatory subunit, cyclin T.
70692	CTDK-1 complex	C	A positive transcription elongation factor complex that comprises the CDK kinase CTK1 (in budding yeast), Lsk1 (in fission yeast) (corresponding to the Panther PTHR24056:SF39 family), a cyclin and an additional gamma subunit (corresponding to the InterPRO entry IPR024638).
70693	P-TEFb-cap methyltransferase complex	C	A protein complex that is formed by the association of positive transcription elongation factor complex b (P-TEFb) with the mRNA capping methyltransferase.
70694	deoxyribonucleoside 5'-monophosphate N-glycosidase activity	F	Catalysis of the reaction: a deoxyribonucleoside 5'-monophosphate + H2O = deoxyribose 5-monophosphate + a purine or pyrimidine base.
70695	FHF complex	C	A protein complex that is composed of AKTIP/FTS, FAM160A2/p107FHIP, and one or more members of the Hook family of proteins, HOOK1, HOOK2, and HOOK3. The complex is thought to promote vesicle trafficking and/or fusion, and associates with the homotypic vesicular sorting complex (the HOPS complex).
70696	transmembrane receptor protein serine/threonine kinase binding	F	Interacting selectively and non-covalently with a receptor that spans a cell membrane and possesses protein serine/threonine kinase activity.
70697	activin receptor binding	F	Interacting selectively and non-covalently with an activin receptor.
70698	type I activin receptor binding	F	Interacting selectively and non-covalently with a type I activin receptor.
70699	type II activin receptor binding	F	Interacting selectively and non-covalently with a type II activin receptor.
70700	BMP receptor binding	F	Interacting selectively and non-covalently with a BMP receptor.
70701	mucus layer	C	An extracellular region part that consists of a protective layer of mucus secreted by epithelial cells lining tubular organs of the body such as the colon or secreted into fluids such as saliva. Mucus is a viscous slimy secretion consisting of mucins (i.e. highly glycosylated mucin proteins) and various inorganic salts dissolved in water, with suspended epithelial cells and leukocytes.
70702	inner mucus layer	C	The inner of two mucus layers secreted by epithelial cells in the colon; the inner mucus layer is firmly attached to the epithelium, is densely packed with a compact stratified appearance and is devoid of bacteria.
70703	outer mucus layer	C	The outer of two mucus layers secreted by epithelial cells in the colon; the outer mucus layer is loosely packed and can be colonized by bacteria.
70704	sterol desaturase activity	F	Catalysis of the introduction of a double bond into a sterol molecule.
70705	RNA nucleotide insertion	P	The modification of an RNA molecule by insertion of one or more nucleotides.
70706	RNA nucleotide deletion	P	The modification of an RNA molecule by removal of a single nucleotide.
70707	RNA dinucleotide insertion	P	The modification of an RNA molecule by insertion of a dinucleotide.
70708	RNA cytidine insertion	P	The modification of an RNA molecule by insertion of a cytidine nucleotide.
70709	RNA guanosine insertion	P	The modification of an RNA molecule by insertion of a guanosine nucleotide.
70710	RNA uridine deletion	P	The modification of an RNA molecule by removal of a uridine nucleotide.
70711	RNA adenosine-uridine insertion	P	The modification of an RNA molecule by insertion of an adenosine-uridine dinucleotide.
70712	RNA cytidine-uridine insertion	P	The modification of an RNA molecule by insertion of an cytidine-uridine dinucleotide.
70713	RNA guanosine-cytidine insertion	P	The modification of an RNA molecule by insertion of an guanosine-cytidine dinucleotide.
70714	RNA guanosine-uridine insertion	P	The modification of an RNA molecule by insertion of an guanosine-uridine insertion dinucleotide.
70715	sodium-dependent organic cation transport	P	The directed, sodium-dependent, movement of organic cations into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
70716	mismatch repair involved in maintenance of fidelity involved in DNA-dependent DNA replication	P	A mismatch repair process that corrects errors introduced that ensures the accuracy of DNA replication.
70717	poly-purine tract binding	F	Interacting selectively and non-covalently with any stretch of purines (adenine or guanine) in an RNA molecule.
70718	alphaPDGFR-SHP-2 complex	C	A protein complex that contains the platelet-derived growth factor alpha receptor (alphaPDGFR; PDGFRA) and the adaptor protein SHP-2, and is involved signaling via the PDGFR signaling pathway.
70719	alphaPDGFR-PLC-gamma-1-PI3K-SHP-2 complex	C	A protein complex that contains the platelet-derived growth factor alpha receptor (alphaPDGFR; PDGFRA), phospholipase C-gamma-1 (PLC-gamma-1), phosphatidylinositol 3-kinase (PI3K) and the adaptor protein SHP-2, and is involved signaling via the PDGFR signaling pathway.
70720	Grb2-SHP-2 complex	C	A protein complex that contains the receptor adaptor proteins Grb2 and SHP-2, and is involved signaling via the PDGFR signaling pathway.
70721	ISGF3 complex	C	A transcription factor complex that consists of a Stat1-Stat2 heterodimer and the IRF9 protein.
70722	Tle3-Aes complex	C	A transcriptional repressor complex that consists of a heterodimer of the proteins Tle3 (also known as Grg3b) and Aes (Grg5), which are homologs of the Drosophila groucho gene product.
70723	response to cholesterol	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cholesterol stimulus.
70724	BMP receptor complex	C	A protein complex that acts as a receptor for bone morphogenetic proteins (BMPs); a homo- or heterodimer of type I and/or type II BMP receptor subunits.
70725	Yb body	C	A cytoplasmic part that appears as an electron-dense sphere of around 1.5 micron diameter containing Yb protein found in somatic cells of ovary and testis. There are one to two Yb bodies per cell.
70726	cell wall assembly	P	The aggregation, arrangement and bonding together of a cell wall. A cell wall is a rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal, and most prokaryotic cells.
70727	cellular macromolecule localization	P	Any process in which a macromolecule is transported to, and/or maintained in, a specific location at the level of a cell. Localization at the cellular level encompasses movement within the cell, from within the cell to the cell surface, or from one location to another at the surface of a cell.
70728	leucine binding	F	Interacting selectively and non-covalently with 2-amino-4-methylpentanoic acid.
70729	cyclic nucleotide transport	P	The directed movement of a cyclic nucleotide, any nucleotide in which phosphate group is in diester linkage to two positions on the sugar residue, into, out of or within a cell.
70730	cAMP transport	P	The directed movement of cyclic AMP (cAMP), into, out of or within a cell.
70731	cGMP transport	P	The directed movement of cyclic GMP (cGMP), into, out of or within a cell.
70732	spindle envelope	C	An organelle envelope that surrounds the chromosomes and the central part of the spindle apparatus during mitosis and meiosis; observed in many invertebrates. The spindle envelope consists of membrane layers, called parafusorial membranes, derived from endoplasmic reticulum membrane; in male meiosis it forms during prometaphase and persists until early in the ensuing interphase.
70733	protein adenylyltransferase activity	F	Catalysis of the reaction: ATP + protein = diphosphate + adenylyl-protein; mediates the addition of an adenylyl (adenosine 5'-monophosphate; AMP group) to specific residues of target proteins.
70734	histone H3-K27 methylation	P	The modification of histone H3 by addition of one or more methyl groups to lysine at position 27 of the histone.
70735	protein-glycine ligase activity	F	Catalysis of the posttranslational transfer of one or more glycine residues to a specific glutamate residue on a target protein.
70736	protein-glycine ligase activity, initiating	F	Catalysis of the posttranslational transfer of a glycine residue to the gamma-carboxyl group(s) of one or more specific glutamate residues on a target protein.
70737	protein-glycine ligase activity, elongating	F	Catalysis of the posttranslational transfer of one or more glycine residues to a glycine residue covalently attached to the gamma-carboxyl group of a glutamate residue on a target protein, resulting in the elongation of a polyglycine side chain.
70738	tubulin-glycine ligase activity	F	Catalysis of the posttranslational transfer of one or more glycine residues to a specific glutamate residue on a target tubulin molecule; acts on alpha or beta tubulin.
70739	protein-glutamic acid ligase activity	F	Catalysis of the posttranslational transfer of one or more glutamate residues to a specific residue on a target protein.
70740	tubulin-glutamic acid ligase activity	F	Catalysis of the posttranslational transfer of one or more glutamate residues to the gamma-carboxyl group(s) of one or more specific glutamate residues on a tubulin molecule.
70741	response to interleukin-6	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-6 stimulus.
70742	C2H2 zinc finger domain binding	F	Interacting selectively and non-covalently with a C2H2-type zinc finger domain of a protein. The C2H2 zinc finger is the classical zinc finger domain, in which two conserved cysteines and histidines co-ordinate a zinc ion.
70743	interleukin-23 complex	C	A protein complex that is composed of an interleukin-23 alpha (p19, product of the IL23A gene) and an interleukin-12 beta (p40, product of the IL12B gene) subunit and is secreted into the extracellular space.
70744	interleukin-27 complex	C	A protein complex that is composed of an interleukin-27p28 subunit (product of the IL27 gene) and an EBI3 subunit and is secreted into the extracellular space.
70745	interleukin-35 complex	C	A protein complex that is composed of an interleukin-12 alpha subunit (p35, product of the IL12A gene) and an EBI3 subunit and is secreted into the extracellular space.
70746	interleukin-35 binding	F	Interacting selectively and non-covalently with interleukin-35.
70747	interleukin-35 receptor activity	F	Combining with interleukin-35 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity.
70748	interleukin-35 receptor binding	F	Interacting selectively and non-covalently with the interleukin-35 receptor.
70749	interleukin-35 biosynthetic process	P	The chemical reactions and pathways resulting in the formation of interleukin-35.
70750	regulation of interleukin-35 biosynthetic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-35.
70751	negative regulation of interleukin-35 biosynthetic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-35.
70752	positive regulation of interleukin-35 biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of interleukin-35.
70753	interleukin-35 production	P	The appearance of interleukin-35 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
70754	regulation of interleukin-35 production	P	Any process that modulates the frequency, rate, or extent of interleukin-35 production.
70755	negative regulation of interleukin-35 production	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of interleukin-35 production.
70756	positive regulation of interleukin-35 production	P	Any process that activates or increases the frequency, rate, or extent of interleukin-35 production.
70757	interleukin-35-mediated signaling pathway	P	A series of molecular signals initiated by the binding of interleukin-35 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.
70758	regulation of interleukin-35-mediated signaling pathway	P	Any process that modulates the rate, frequency or extent of the series of molecular events generated as a consequence of interleukin-35-mediated binding to a cell surface receptor.
70759	negative regulation of interleukin-35-mediated signaling pathway	P	Any process that decreases the rate, frequency or extent of the series of molecular events generated as a consequence of interleukin-35 binding to a cell surface receptor.
70760	positive regulation of interleukin-35-mediated signaling pathway	P	Any process that increases the rate, frequency or extent of the series of molecular events generated as a consequence of interleukin-35 binding to a cell surface receptor.
70761	pre-snoRNP complex	C	A ribonucleoprotein complex that contains a precursor small nucleolar RNA (pre-snoRNA) and associated proteins, and forms during small nucleolar ribonucleoprotein complex (snoRNP) assembly. Pre-snoRNP complexes may contain proteins not found in the corresponding mature snoRNP complexes.
70762	nuclear pore transmembrane ring	C	A subcomplex of the nuclear pore complex (NPC) that spans the nuclear membrane and anchors the NPC to the nuclear envelope. In S. cerevisiae, the transmembrane ring is composed of Pom152p, Pom34p, and Ndc1p. In vertebrates, it is composed of Gp210, Ndc1, and Pom121. Components are arranged in 8-fold symmetrical 'spokes' around the central transport channel. A single 'spoke', can be isolated and is sometime referred to as the Ndc1 complex.
70763	Delta1 complex	C	A protein complex that consists of homodimer of the Notch ligand Delta1.
70764	gamma-secretase-Delta1 complex	C	A protein complex that is formed by the association of the Notch ligand Delta1 with the gamma-secretase complex.
70765	gamma-secretase complex	C	A protein complex that has aspartic-type endopeptidase activity, and contains a catalytic subunit, presenilin (PS), that is a prototypical member of the GxGD-type aspartyl peptidases. The complex also contains additional subunits, including nicastrin, APH-1, PEN-2, and a regulatory subunit, CD147. Gamma-secretase cleaves several transmembrane proteins including the cell surface receptor Notch and the beta-amyloid precursor protein.
70766	endobrevin-synaptobrevin 2-alpha-SNAP-NSF-syntaxin-4 complex	C	A SNARE complex that contains endobrevin (VAMP8), synaptobrevin 2 (VAMP2), alpha-SNAP, NSF, and syntaxin 4 (or orthologs thereof).
70767	BRCA1-Rad51 complex	C	A protein complex that contains BRCA1 and Rad 51, and is involved in the control of recombination and of genome integrity.
70768	synaptotagmin-synaptobrevin 2-SNAP-25-syntaxin-1a-syntaxin-1b-Unc13 complex	C	A SNARE complex that contains synaptotagmin, synaptobrevin 2 (VAMP2), SNAP-25, syntaxin 1a, syntaxin1b, and Unc13b (or orthologs thereof).
70769	alphaIIb-beta3 integrin-CIB complex	C	A protein complex that consists of an alphaIIb-beta3 integrin complex bound to CIB, a protein that binds calcium as well as the alphaIIb-beta3 integrin.
70770	alphaIIb-beta3 integrin-CD47-FAK complex	C	A protein complex that consists of an alphaIIb-beta3 integrin complex bound to the cell surface antigen CD47 and the kinase FAK.
70771	alphaIIb-beta3 integrin-CD47-Src complex	C	A protein complex that consists of an alphaIIb-beta3 integrin complex bound to the cell surface antigen CD47 and the kinase c-Src.
70772	PAS complex	C	A class III phosphatidylinositol 3-kinase complex that contains a phosphatidylinositol-3-phosphate 5-kinase subunit (Fab1p in yeast; PIKfyve in mammals), a kinase activator, and a phosphatase, and may also contain additional proteins; it is involved in regulating the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate. In mammals the complex is composed of PIKFYVE, FIG4 and VAC14. In yeast it is composed of Atg18p, Fig4p, Fab1p, Vac14p and Vac7p.
70773	protein-N-terminal glutamine amidohydrolase activity	F	Catalysis of the reaction: protein-N-terminal-L-glutamine + H2O = protein-N-terminal-L-glutamate + NH3. This reaction is the deamidation of an N-terminal glutamine residue of a protein.
70774	phytoceramidase activity	F	Catalysis of the reaction: a phytoceramide + H2O = a fatty acid + phytosphingosine.
70775	H3 histone acetyltransferase complex	C	A multisubunit complex that catalyzes the acetylation of histone H3.
70776	MOZ/MORF histone acetyltransferase complex	C	A histone acetyltransferase complex that has histone H3 acetyltransferase and coactivator activities. Subunits of the human complex include MYST3/MOZ, MYST4/MORF, ING5, EAF6 and one of BRPF1, BRD1/BRPF2 and BRPF3.
70777	D-aspartate transport	P	The directed movement of D-aspartate, the D-enantiomer of the anion of (2R)-2-aminobutanedioic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
70778	L-aspartate transport	P	The directed movement of L-aspartate, the L-enantiomer of the anion of (2R)-2-aminobutanedioic acid, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
70779	D-aspartate import	P	The directed movement of D-aspartate, the L-enantiomer of the anion of 2-aminopentanedioic acid, into a cell or organelle.
70780	dihydrosphingosine-1-phosphate phosphatase activity	F	Catalysis of the reaction: dihydrosphingosine 1-phosphate + H2O = dihydrosphingosine + phosphate.
70781	response to biotin	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a biotin stimulus.
70782	phosphatidylserine exposure on apoptotic cell surface	P	A phospholipid scrambling process that results in the appearance of phosphatidylserine on the outer leaflet of the plasma membrane of an apoptotic cell, which acts as an 'eat-me' signal for engulfing cells. Phosphatidylserine is exposed on the apoptotic cell surface by a phospholipid scramblase activity.
70783	growth of unicellular organism as a thread of attached cells	P	A filamentous growth process in which cells remain attached after division and form thread-like filaments that may penetrate into a solid growth medium such as an agar plate, exhibited by unicellular fungi under certain growth conditions.
70784	regulation of growth of unicellular organism as a thread of attached cells	P	Any process that modulates the frequency, rate or extent of the process in which cells remain attached after division and form thread-like filaments that may penetrate into a solid growth medium.
70785	negative regulation of growth of unicellular organism as a thread of attached cells	P	Any process that decreases the frequency, rate or extent of the process in which cells remain attached after division and form thread-like filaments that may penetrate into a solid growth medium.
70786	positive regulation of growth of unicellular organism as a thread of attached cells	P	Any process that activates or increases the frequency, rate or extent of the process in which cells remain attached after division and form thread-like filaments that may penetrate into a solid growth medium.
70787	conidiophore development	P	The process whose specific outcome is the progression of the conidiophore over time, from its formation to the mature structure. The conidiophore is a specialized hypha that extends aerially from the growth substrate and bears conidia, or asexual spores.
70788	conidiophore stalk development	P	The process whose specific outcome is the progression of the conidiophore stalk over time, from its formation to the mature structure. The conidiophore stalk is part of a specialized hypha that extends aerially from the growth substrate and supports structures from which conidia, or asexual spores, develop.
70789	metula development	P	The process whose specific outcome is the progression of metulae over time, from its formation to the mature structure. Metulae are elongated mononucleate cells that bud from the surface of the conidiophore tip.
70790	phialide development	P	The process whose specific outcome is the progression of phialides over time, from its formation to the mature structure. Phialides are specialized cells that bud from the ends of metulae on the conidiophore tip. Chains of conidia, or asexual spores, develop from the phialide tips.
70791	cleistothecium development	P	The process whose specific outcome is the progression of the cleistothecium over time, from its formation to the mature structure. The cleistothecium is a closed sexual fruiting body that contains ascospores in linear asci, characteristic of some filamentous Ascomycete fungi such as members of the genera Aspergillus and Emericella.
70792	Hulle cell development	P	The process whose specific outcome is the progression of Hulle cells over time, from their formation to the mature structures. Hulle cells are specialized multinucleate cells that originate from a nest-like aggregation of hyphae during sexual development and serve as nurse cells to the developing cleistothecium, or fruiting body.
70793	regulation of conidiophore development	P	Any process that modulates the frequency, rate or extent of conidiophore development, a process that leads to the formation of a conidiophore. The conidiophore is a specialized hypha that extends aerially from the growth substrate and bears conidia, or asexual spores.
70794	negative regulation of conidiophore development	P	Any process that stops, prevents, or reduces the frequency, rate or extent of conidiophore development, a process that leads to the formation of a conidiophore. The conidiophore is a specialized hypha that extends aerially from the growth substrate and bears conidia, or asexual spores.
70795	positive regulation of conidiophore development	P	Any process that activates or increases the frequency, rate or extent of conidiophore development, a process that leads to the formation of a conidiophore. The conidiophore is a specialized hypha that extends aerially from the growth substrate and bears conidia, or asexual spores.
70796	regulation of cleistothecium development	P	Any process that modulates the frequency, rate or extent of cleistothecium development, a process that leads to the formation of a cleistothecium. The cleistothecium is a closed sexual fruiting body that contains ascospores in linear asci, characteristic of some filamentous Ascomycete fungi such as members of the genera Aspergillus and Emericella.
70797	negative regulation of cleistothecium development	P	Any process that stops, prevents, or reduces the frequency, rate or extent of cleistothecium development, a process that leads to the formation of a cleistothecium. The cleistothecium is a closed sexual fruiting body that contains ascospores in linear asci, characteristic of some filamentous Ascomycete fungi such as members of the genera Aspergillus and Emericella.
70798	positive regulation of cleistothecium development	P	Any process that activates or increases the frequency, rate or extent of cleistothecium development, a process that leads to the formation of a cleistothecium. The cleistothecium is a closed sexual fruiting body that contains ascospores in linear asci, characteristic of some filamentous Ascomycete fungi such as members of the genera Aspergillus and Emericella.
70799	regulation of conidiophore stalk development	P	Any process that modulates the frequency, rate or extent of conidiophore stalk development, a process that leads to the formation of a conidiophore stalk. The conidiophore stalk is part of a specialized hypha that extends aerially from the growth substrate and supports structures from which conidia, or asexual spores, develop.
70800	negative regulation of conidiophore stalk development	P	Any process that stops, prevents, or reduces the frequency, rate or extent of conidiophore stalk development, a process that leads to the formation of a conidiophore stalk. The conidiophore stalk is part of a specialized hypha that extends aerially from the growth substrate and supports structures from which conidia, or asexual spores, develop.
70801	positive regulation of conidiophore stalk development	P	Any process that activates or increases the frequency, rate or extent of conidiophore stalk development, a process that leads to the formation of a conidiophore stalk. The conidiophore stalk is part of a specialized hypha that extends aerially from the growth substrate and supports structures from which conidia, or asexual spores, develop.
70802	regulation of metula development	P	Any process that modulates the frequency, rate or extent of metula development, a process that leads to the formation of metulae. Metulae are elongated mononucleate cells that bud from the surface of the conidiophore tip.
70803	negative regulation of metula development	P	Any process that stops, prevents, or reduces the frequency, rate or extent of metula development, a process that leads to the formation of metulae. Metulae are elongated mononucleate cells that bud from the surface of the conidiophore tip.
70804	positive regulation of metula development	P	Any process that activates or increases the frequency, rate or extent of metula development, a process that leads to the formation of metulae. Metulae are elongated mononucleate cells that bud from the surface of the conidiophore tip.
70805	regulation of phialide development	P	Any process that modulates the frequency, rate or extent of phialide development, a process that leads to the formation of phialides. Phialides are specialized cells that bud from the ends of metulae on the conidiophore tip.
70806	negative regulation of phialide development	P	Any process that stops, prevents, or reduces the frequency, rate or extent of phialide development, a process that leads to the formation of phialides. Phialides are specialized cells that bud from the ends of metulae on the conidiophore tip.
70807	positive regulation of phialide development	P	Any process that activates or increases the frequency, rate or extent of phialide development, a process that leads to the formation of phialides. Phialides are specialized cells that bud from the ends of metulae on the conidiophore tip.
70808	regulation of Hulle cell development	P	Any process that modulates the frequency, rate or extent of Hulle cell development, a process that leads to the formation of Hulle cells. Hulle cells are specialized multinucleate cells that originate from a nest-like aggregation of hyphae during sexual development and serve as nurse cells to the developing cleistothecium, or fruiting body.
70809	negative regulation of Hulle cell development	P	Any process that stops, prevents, or reduces the frequency, rate or extent of Hulle cell development, a process that leads to the formation of Hulle cells. Hulle cells are specialized multinucleate cells that originate from a nest-like aggregation of hyphae during sexual development and serve as nurse cells to the developing cleistothecium, or fruiting body.
70810	positive regulation of Hulle cell development	P	Any process that activates or increases the frequency, rate or extent of Hulle cell development, a process that leads to the formation of Hulle cells. Hulle cells are specialized multinucleate cells that originate from a nest-like aggregation of hyphae during sexual development and serve as nurse cells to the developing cleistothecium, or fruiting body.
70811	glycerol-2-phosphate transport	P	The directed movement of glycerol-2-phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Glycerol-2-phosphate is a phosphoric monoester of glycerol.
70812	glycerol-2-phosphate-transporting ATPase activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + glycerol-2-phosphate(out) = ADP + phosphate + glycerol-2-phosphate(in).
70813	hydrogen sulfide metabolic process	P	The chemical reactions and pathways involving hydrogen sulfide, H2S.
70814	hydrogen sulfide biosynthetic process	P	The chemical reactions and pathways resulting in the formation of hydrogen sulfide, H2S.
70815	peptidyl-lysine 5-dioxygenase activity	F	Catalysis of the reaction: protein L-lysine + 2-oxoglutarate + O2 = protein 5-hydroxy-L-lysine + succinate + CO2.
70816	phosphorylation of RNA polymerase II C-terminal domain	P	The process of introducing a phosphate group on to an amino acid residue in the C-terminal domain of RNA polymerase II. Typically, this occurs during the transcription cycle and results in production of an RNA polymerase II enzyme where the carboxy-terminal domain (CTD) of the largest subunit is extensively phosphorylated, often referred to as hyperphosphorylated or the II(0) form. Specific types of phosphorylation within the CTD are usually associated with specific regions of genes, though there are exceptions. The phosphorylation state regulates the association of specific complexes such as the capping enzyme or 3'-RNA processing machinery to the elongating RNA polymerase complex.
70817	P-TEFb-cap methyltransferase complex localization	P	Any process in which the P-TEFb-cap methyltransferase complex is transported to, or maintained in, a specific location.
70818	protoporphyrinogen oxidase activity	F	Catalysis of the reaction: protoporphyrinogen IX + acceptor = protoporphyrin IX + reduced acceptor.
70819	menaquinone-dependent protoporphyrinogen oxidase activity	F	Catalysis of the reaction: protoporphyrinogen IX + menaquinone = protoporphyrin IX + reduced menaquinone.
70820	tertiary granule	C	A secretory granule that contains cathepsin and gelatinase and is readily exocytosed upon cell activation; found primarily in mature neutrophil cells.
70821	tertiary granule membrane	C	The lipid bilayer surrounding a tertiary granule.
70822	Sin3-type complex	C	Any of a number of evolutionarily conserved histone deacetylase complexes (HDACs) containing a core consisting of a paired amphipathic helix motif protein (e.g. Sin3p in S. cerevisiae, Pst1 in S. pombe or Sin3A in mammals) at least one class I histone deacetylase (e.g. Rpd3p in S. cerevisiae, Clr6 in S. pombe, or HDAC1 and HDAC2 in mammals), and at least one WD40 repeat protein (e.g. Ume1p in S. cerevisiae, Prw1 in S. pombe, or RbAp46 and RbAp48 in mammals). These complexes also contain a variable number of other proteins that direct histone binding, DNA binding, or add other functionality to the complex.
70823	HDA1 complex	C	A tetrameric histone deacetylase complex that contains a Class II deacetylase catalytic subunit. In S. cerevisiae it is composed of two Hda1p subunits along with Hda2p and Hda3p.
70824	SHREC complex	C	A histone deacetylase complex that contains a core of four proteins -- Clr1, Clr2, Clr3, and Mit1 in fission yeast -- and localizes to all heterochromatic regions in the genome as well as some euchromatic sites. The complex is involved in regulating nucleosome positioning to assemble higher-order chromatin structures.
70825	micropyle	C	An external encapsulating structure part of the chorion. A single cone-shaped specialization that forms an opening in the chorion that allows sperm entry into the egg prior to fertilization.
70826	paraferritin complex	C	A cytoplasmic protein complex that contains integrin, mobilferrin and a flavin monooxygenase, is capable of reducing Fe(III) to Fe(II) utilizing NADPH, and is involved in iron transport. Fe(II) is required in the cell as the substrate for ferrochelatase in the synthesis of heme.
70827	chromatin maintenance	P	The chromatin organization process that preserves chromatin in a stable functional or structural state.
70828	heterochromatin organization	P	Any process that results in the specification, formation or maintenance of the physical structure of eukaryotic heterochromatin, a compact and highly condensed form of chromatin.
70829	heterochromatin maintenance	P	The chromatin organization process that preserves heterochromatin in a stable functional or structural state.
70830	bicellular tight junction assembly	P	The aggregation, arrangement and bonding together of a set of components to form a tight junction, an occluding cell-cell junction that is composed of a branching network of sealing strands that completely encircles the apical end of each cell in an epithelial sheet.
70831	basement membrane assembly	P	The aggregation, arrangement and bonding together of a set of components to form a basement membrane, a part of the extracellular region that consists of a thin layer of dense material found in various animal tissues interposed between the cells and the adjacent connective tissue.
70832	phosphatidylcholine biosynthesis from phosphoryl-ethanolamine via N-dimethylethanolamine phosphate and CDP-choline	P	The phosphatidylcholine biosynthetic process that begins with three consecutive N-methylation steps that are carried out on phospho-bases, phosphoethanolamine, phospho-N-methylethanolamine, and phospho-N-dimethylethanolamine; the process ends with the conversion of a phosphatidyl-N-dimethylethanolamine to a phosphatidylcholine.
70833	phosphatidylcholine biosynthesis from phosphoryl-ethanolamine via CDP-N-methylethanolamine	P	The phosphatidylcholine biosynthetic process that begins with an initial N-methylation with phospho-base phosphoethanolamine, followed by two downstream N-methylations on phosphatidyl-bases, phosphatidyl-N-methylethanolamine and phosphatidyl-N-dimethylethanolamine. The process ends with the conversion of a phosphatidyl-N-dimethylethanolamine to a phosphatidylcholine.
70834	phosphatidylcholine biosynthesis from phosphoryl-ethanolamine via N-dimethylethanolamine phosphate and CDP-N-dimethylethanolamine	P	The phosphatidylcholine biosynthetic process that begins with two N-methylations with phospho-base phosphoethanolamine and phospho-N-methylethanolamine, followed by a downstream N-methylation on phosphatidyl-base phosphatidyl-N-dimethylethanolamine; the process ends with the conversion of a phosphatidyl-N-dimethylethanolamine to a phosphatidylcholine.
70835	chromium ion transmembrane transporter activity	F	Enables the transfer of chromium (Cr) ions from one side of a membrane to the other.
70836	caveola assembly	P	The aggregation, arrangement and bonding together of a set of components to form a caveola. A caveola is a plasma membrane raft that forms a small pit, depression, or invagination that communicates with the outside of a cell and extends inward, indenting the cytoplasm and the cell membrane.
70837	dehydroascorbic acid transport	P	The directed movement of dehydroascorbate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Dehydroascorbate, 5-(1,2-dihydroxyethyl)furan-2,3,4(5H)-trione, is an oxidized form of vitamin C.
70838	divalent metal ion transport	P	The directed movement of divalent metal cations, any metal ion with a +2 electric charge, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
70839	divalent metal ion export	P	The directed movement of divalent metal cations, any metal ion with a +2 electric charge, out of a cell or organelle.
70840	dynein complex binding	F	Interacting selectively and non-covalently with a dynein complex, a protein complex that contains two or three dynein heavy chains and several light chains, and has microtubule motor activity.
70841	inclusion body assembly	P	The aggregation, arrangement and bonding together of a set of components to form an inclusion body.
70842	aggresome assembly	P	The aggregation, arrangement and bonding together of a set of components to form an aggresome; requires the microtubule cytoskeleton and dynein.
70843	misfolded protein transport	P	The directed movement of misfolded proteins in a cell, including the movement of proteins between specific compartments or structures within a cell.
70844	polyubiquitinated protein transport	P	The directed movement of polyubiquitinated proteins in a cell, including the movement of proteins between specific compartments or structures within a cell.
70845	polyubiquitinated misfolded protein transport	P	The directed movement of misfolded polyubiquitinated proteins in a cell, including the movement of proteins between specific compartments or structures within a cell.
70846	Hsp90 deacetylation	P	The modification of an Hsp90 protein by removal of acetyl groups.
70847	core mediator complex	C	A protein complex that interacts with the carboxy-terminal domain of the largest subunit of RNA polymerase II and plays an active role in transducing the signal from a transcription factor to the transcriptional machinery. The core mediator complex has a stimulatory effect on basal transcription, and contains most of the same subdomains as the larger form of mediator complex -- a head domain comprising proteins known in Saccharomyces as Srb2, -4, and -5, Med6, -8, and -11, and Rox3 proteins; a middle domain comprising Med1, -4, and -7, Nut1 and -2, Cse2, Rgr1, Soh1, and Srb7 proteins; and a tail consisting of Gal11p, Med2p, Pgd1p, and Sin4p -- but lacks the regulatory subcomplex comprising Ssn2, -3, and -8, and Srb8 proteins. Metazoan core mediator complexes have similar modular structures and include homologs of yeast Srb and Med proteins.
70848	response to growth factor	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a growth factor stimulus.
70849	response to epidermal growth factor	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an epidermal growth factor stimulus.
70850	TACC/TOG complex	C	A protein complex that contains the transforming acidic coiled coil (TACC) protein and the TOG protein (Mia1p/Alp7p and Alp14, respectively, in fission yeast), and is involved in microtubule array remodeling as cells progress through the cell cycle. The TACC/TOG complex is conserved in eukaryotes, associates with microtubules, and shuttles between the nucleus and the cytoplasm during interphase.
70851	growth factor receptor binding	F	Interacting selectively and non-covalently with a growth factor receptor.
70852	cell body fiber	C	A neuron projection that is found in unipolar neurons and corresponds to the region between the cell body and the point at which the single projection branches.
70853	myosin VI binding	F	Interacting selectively and non-covalently with a class VI myosin. The myosin VI heavy chain has a single IQ motif in the neck and a tail region with a coiled coil domain followed by a unique globular domain, a unique insertion that enables myosin VI to move towards the pointed or minus end of actin filaments.
70854	myosin VI heavy chain binding	F	Interacting selectively and non-covalently with a heavy chain of a myosin VI complex.
70855	myosin VI head/neck binding	F	Interacting selectively and non-covalently with the head/neck region of a myosin VI heavy chain.
70856	myosin VI light chain binding	F	Interacting selectively and non-covalently with a light chain of a myosin VI complex.
70857	regulation of bile acid biosynthetic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of bile acids.
70858	negative regulation of bile acid biosynthetic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of bile acids.
70859	positive regulation of bile acid biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of bile acids.
70860	RNA polymerase I core factor complex	C	A RNA polymerase I-specific transcription factor complex that is required for the transcription of rDNA by RNA polymerase I. In yeast the complex consists of Rrn6p, Rrn7p, and Rrn11p.
70861	regulation of protein exit from endoplasmic reticulum	P	Any process that modulates the frequency, rate or extent of the directed movement of proteins from the endoplasmic reticulum.
70862	negative regulation of protein exit from endoplasmic reticulum	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of proteins from the endoplasmic reticulum.
70863	positive regulation of protein exit from endoplasmic reticulum	P	Any process that activates or increases the frequency, rate or extent of directed movement of proteins from the endoplasmic reticulum.
70864	sperm individualization complex	C	A macromolecular complex that includes cytoskeletal components and part of the cell membrane. Forms at the nuclear end of a male germline syncytium, or cyst, and translocates the over the length of the syncytium in the course of sperm individualization. Each complex contains an array of 64 investment cones, one per nucleus, that move synchronously along the spermatogenic cyst.
70865	investment cone	C	A cytoskeletal part that consists of a microfilament-rich cone that forms round each nucleus in a spermatogenic cyst and translocates the length of the cyst during sperm individualization.
70866	sterol-dependent protein binding	F	Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules) in the presence of sterols.
70867	mating projection tip membrane	C	The portion of the plasma membrane surrounding a mating projection tip.
70868	heterochromatin organization involved in chromatin silencing	P	Any process that results in the specification, formation or maintenance of the physical structure of eukaryotic heterochromatin and contributes to chromatin silencing.
70869	heterochromatin assembly involved in chromatin silencing	P	Any process that results in the assembly of chromatin into heterochromatin and contributes to chromatin silencing.
70870	heterochromatin maintenance involved in chromatin silencing	P	A chromatin organization process that preserves heterochromatin in a stable functional or structural state, and that contributes to chromatin silencing.
70871	cell wall organization involved in conjugation with cellular fusion	P	A process of cell wall organization that contributes to conjugation with cellular fusion.
70872	plasma membrane organization involved in conjugation with cellular fusion	P	A process of plasma membrane organization that contributes to conjugation with cellular fusion.
70873	regulation of glycogen metabolic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving glycogen.
70874	negative regulation of glycogen metabolic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving glycogen.
70875	positive regulation of glycogen metabolic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways involving glycogen.
70876	SOSS complex	C	A protein complex that functions downstream of the MRN complex to promote DNA repair and the G2/M checkpoint. The SOSS complex associates with single-stranded DNA at DNA lesions and is composed of SOSS-B (SOSS-B1/OBFC2B or SOSS-B2/OBFC2A), SOSS-A/INTS3 and SOSS-C/C9orf80.
70877	microprocessor complex	C	A protein complex that binds to heme and to pri-miRNAs, and is required for the formation of a pre-microRNA (pre-miRNA), the initial step of microRNA (miRNA) biogenesis. The complex is composed of the double-stranded-RNA-specific RNase Drosha (also called RNASEN) and the RNA-binding protein DGCR8 (heme-free or heme-bound forms). Within the complex, DGCR8 function as a molecular anchor necessary for the recognition of pri-miRNA at dsRNA-ssRNA junction and directs RNASEN/Drosha to cleave the 3' and 5' strands of a stem-loop to release hairpin-shaped pre-miRNAs.
70878	primary miRNA binding	F	Interacting selectively and non-covalently with a primary microRNA (pri-miRNA) transcript, an RNA molecule that is processed into a short hairpin-shaped structure called a pre-miRNA and finally into a functional miRNA. Both double-stranded and single-stranded regions of a pri-miRNA are required for binding.
70879	fungal-type cell wall beta-glucan metabolic process	P	The chemical reactions and pathways involving beta-glucans, compounds composed of glucose residues linked by beta-D-glucosidic bonds, found in the walls of fungal cells.
70880	fungal-type cell wall beta-glucan biosynthetic process	P	The chemical reactions and pathways resulting in the formation of beta-glucans, compounds composed of glucose residues linked by beta-D-glucosidic bonds, found in the walls of fungal cells.
70881	regulation of proline transport	P	Any process that modulates the frequency, rate or extent of proline transport.
70883	pre-miRNA binding	F	Interacting selectively and non-covalently with a precursor microRNA (pre-miRNA) transcript, a stem-loop-containing precursor of microRNA.
70884	regulation of calcineurin-NFAT signaling cascade	P	Any process that modulates the frequency, rate or extent of the calcineurin-NFAT signaling cascade.
70885	negative regulation of calcineurin-NFAT signaling cascade	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the calcineurin-NFAT signaling cascade.
70886	positive regulation of calcineurin-NFAT signaling cascade	P	Any process that activates or increases the frequency, rate or extent of signaling via the calcineurin-NFAT signaling cascade.
70887	cellular response to chemical stimulus	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemical stimulus.
70888	E-box binding	F	Interacting selectively and non-covalently with an E-box, a DNA motif with the consensus sequence CANNTG that is found in the promoters of a wide array of genes expressed in neurons, muscle and other tissues.
70889	platelet alpha granule organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a platelet alpha granule. A platelet alpha granule is a secretory organelle found in blood platelets.
70890	sodium-dependent L-ascorbate transmembrane transporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: L-ascorbate(out) + Na+(out) = L-ascorbate(in) + Na+(in).
70891	lipoteichoic acid binding	F	Interacting selectively and non-covalently with lipoteichoic acid.
70892	lipoteichoic acid receptor activity	F	Combining with lipoteichoic acid and transmitting the signal to initiate a change in cell activity.
70893	transposon integration	P	Any process in which a transposable element is incorporated into another DNA molecule such as a chromosome.
70894	regulation of transposon integration	P	Any process that modulates the frequency, rate or extent of regulation of transposon integration, a process in which a transposable element is incorporated into another DNA molecule.
70895	negative regulation of transposon integration	P	Any process that stops, prevents, or reduces the frequency, rate or extent of transposon integration, a process in which a transposable element is incorporated into another DNA molecule.
70896	positive regulation of transposon integration	P	Any process that activates or increases the frequency, rate or extent of transposon integration, a process in which a transposable element is incorporated into another DNA molecule.
70897	DNA-templated transcriptional preinitiation complex assembly	P	The aggregation, arrangement and bonding together of proteins on promoter DNA to form the transcriptional preinitiation complex (PIC), the formation of which is a prerequisite for transcription.
70898	RNA polymerase III transcriptional preinitiation complex assembly	P	The aggregation, arrangement and bonding together of proteins on promoter DNA to form the transcriptional preinitiation complex (PIC), the formation of which is a prerequisite for transcription from an RNA polymerase III promoter.
70899	mitochondrial tRNA wobble uridine modification	P	The process in which a uridine in position 34 of a mitochondrial tRNA is post-transcriptionally modified.
70900	mitochondrial tRNA modification	P	The covalent alteration of one or more nucleotides within a mitochondrial tRNA molecule to produce a mitochondrial tRNA molecule with a sequence that differs from that coded genetically.
70901	mitochondrial tRNA methylation	P	The posttranscriptional addition of methyl groups to specific residues in a mitochondrial tRNA molecule.
70902	mitochondrial tRNA pseudouridine synthesis	P	The intramolecular conversion of uridine to pseudouridine in a mitochondrial tRNA molecule.
70903	mitochondrial tRNA thio-modification	P	The addition a sulfur atom to a nucleotide in a mitochondrial tRNA molecule.
70904	transepithelial L-ascorbic acid transport	P	The directed movement of L-ascorbic acid from one side of an epithelium to the other.
70905	serine binding	F	Interacting selectively and non-covalently with 2-amino-3-hydroxypropanoic acid.
70906	aspartate:alanine antiporter activity	F	Catalysis of the reaction: aspartate(out) + alanine(in) = aspartate(in) + alanine(out).
70907	histidine:histamine antiporter activity	F	Catalysis of the reaction: histidine(out) + histamine(in) = histidine(in) + histamine(out).
70908	tyrosine:tyramine antiporter activity	F	Catalysis of the reaction: tyrosine(out) + tyramine(in) = tyrosine(in) + tyramine(out).
70909	glutamate:gamma-aminobutyric acid antiporter activity	F	Catalysis of the reaction: glutamate(out) + gamma-aminobutyric acid(in) = glutamate(in) + gamma-aminobutyric acid(out).
70910	cell wall macromolecule catabolic process involved in cell wall disassembly	P	The chemical reactions and pathways that result in the breakdown of macromolecules that form part of a cell wall, and contributes to the breakdown of the cell wall.
70911	global genome nucleotide-excision repair	P	The nucleotide-excision repair process in which DNA lesions are removed from nontranscribed strands and from transcriptionally silent regions over the entire genome.
70912	Ddb1-Ckn1 complex	C	A heterodimeric nucleotide-excision repair complex that is involved in transcription-coupled repair. The subunits are known as Ddb1 and Ckn1 in S. pombe; Ddb1 contains a motif called the DDB-box that interacts with adaptor proteins for DDB1/cullin 4 ubiquitin ligases.
70913	Ddb1-Wdr21 complex	C	A heterodimeric nucleotide-excision repair complex that is involved in transcription-coupled repair. The subunits are known as Ddb1 and Wdr21 in S. pombe; Ddb1 contains a motif called the DDB-box that interacts with adaptor proteins for DDB1/cullin 4 ubiquitin ligases.
70914	UV-damage excision repair	P	A DNA repair process that is initiated by an endonuclease that introduces a single-strand incision immediately 5' of a UV-induced damage site. UV-damage excision repair acts on both cyclobutane pyrimidine dimers (CPDs) and pyrimidine-pyrimidone 6-4 photoproducts (6-4PPs).
70915	lysophosphatidic acid receptor activity	F	Combining with the phospholipid derivative lysophosphatidic acid, and transmitting the signal across the membrane by activating an associated G-protein.
70916	inositol phosphoceramide synthase complex	C	A protein complex that possesses inositol phosphoceramide synthase activity and contains a catalytic subunit and a regulatory subunit (Aur1p and Kei1p, respectively, in Saccharomyces).
70917	inositol phosphoceramide synthase regulator activity	F	Modulates the activity of inositol phosphoceramide synthase.
70918	production of small RNA involved in gene silencing by RNA	P	The process in which a double-stranded RNA precursor is processed into short (20-30 nt) fragments. RNA cleavage is catalyzed by a Dicer endonuclease.
70919	production of siRNA involved in chromatin silencing by small RNA	P	Cleavage of double-stranded RNA to form small interfering RNA molecules (siRNAs) of 21-23 nucleotides, in the context of chromatin silencing by small RNA.
70920	regulation of production of small RNA involved in gene silencing by RNA	P	Any process that modulates the frequency, rate or extent of the production of small RNA involved in gene silencing by RNA.
70921	regulation of production of siRNA involved in chromatin silencing by small RNA	P	Any process that modulates the frequency, rate or extent of the production of siRNA, the cleavage of double-stranded RNA to form small interfering RNA molecules (siRNAs) of 21-23 nucleotides, in the context of chromatin silencing by small RNA.
70922	small RNA loading onto RISC	P	The process in which a single-stranded small RNA associates with the RNA-initiated silencing complex (RISC); occurs as part of a process of gene silencing by small RNA.
70923	siRNA loading onto RISC involved in chromatin silencing by small RNA	P	The process in which a single-stranded small RNA associates with the RNA-initiated silencing complex (RISC); occurs as part of a process of chromatin silencing by small RNA.
70924	heterochromatin assembly involved in chromatin silencing by small RNA	P	The process in which an siRNA-associated RNA-induced silencing complex (siRISC) associates with nascent transcripts and RNA polymerase to induce the formation of heterochromatin.
70925	organelle assembly	P	The aggregation, arrangement and bonding together of a set of components to form an organelle. An organelle is an organized structure of distinctive morphology and function. Includes the nucleus, mitochondria, plastids, vacuoles, vesicles, ribosomes and the cytoskeleton. Excludes the plasma membrane.
70926	regulation of ATP:ADP antiporter activity	P	Any process that modulates the activity of an ATP:ADP antiporter.
70927	negative regulation of ATP:ADP antiporter activity	P	Any process that stops or reduces the activity of an ATP:ADP antiporter.
70928	regulation of mRNA stability, ncRNA-mediated	P	Any process, mediated by small non-coding RNAs, that modulates the propensity of mRNA molecules to degradation. Includes processes that both stabilize and destabilize mRNAs.
70929	trans-translation	P	A translational elongation process in which transfer of a translating ribosome from one mRNA to another RNA template takes place. Trans-translation occurs during tmRNA release of stalled ribosomes.
70930	trans-translation-dependent protein tagging	P	A protein modification process in which a polypeptide is added to a nascent polypeptide cotranslationally by trans-translation.
70931	Golgi-associated vesicle lumen	C	The volume enclosed by the membrane of a Golgi-associated vesicle.
70932	histone H3 deacetylation	P	The modification of histone H3 by the removal of one or more acetyl groups.
70933	histone H4 deacetylation	P	The modification of histone H4 by the removal of one or more acetyl groups.
70934	CRD-mediated mRNA stabilization	P	An mRNA stabilization process in which one or more RNA-binding proteins associate with a sequence in the open reading frame called the coding region instability determinant (CRD).
70935	3'-UTR-mediated mRNA stabilization	P	An mRNA stabilization process in which one or more RNA-binding proteins associate with the 3'-untranslated region (UTR) of an mRNA.
70936	protein K48-linked ubiquitination	P	A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 48 of the ubiquitin monomers, is added to a protein. K48-linked ubiquitination targets the substrate protein for degradation.
70937	CRD-mediated mRNA stability complex	C	A protein complex that binds to, and promotes stabilization of, mRNA molecules containing the coding region instability determinant (CRD). In human, IGF2BP1 and at least four additional proteins: HNRNPU, SYNCRIP, YBX1, and DHX9.
70938	contractile ring	C	A cytoskeletal structure composed of filamentous protein that forms beneath the membrane of many cells or organelles, in the plane of cell or organelle division. Ring contraction is associated with centripetal growth of the membrane that divides the cytoplasm of the two daughter cells or organelles.
70939	Dsl1/NZR complex	C	A multisubunit tethering complex, i.e. a protein complex involved in mediating the initial interaction between vesicles and the membranes with which they fuse, that is involved in trafficking from the Golgi apparatus to the ER. In Saccharomyces cerevisiae the Dsl1p complex contains Dsl1p, Tip20p, and Sec39p.
70940	dephosphorylation of RNA polymerase II C-terminal domain	P	The process of removing a phosphate group from an amino acid residue in the C-terminal domain of RNA polymerase II. Some dephosphorylation occurs during transcription while some may occur after the enzyme is released from the template in order to prepare it for the beginning of the transcription cycle again. RNA polymerase II with little or no phosphorylation is referred to as the hypophosphorylated or II(A) form.
70941	eisosome assembly	P	The aggregation, arrangement and bonding together of a set of components to form an eisosome, a cell part that is composed of the eisosome membrane or MCC domain, a furrow-like plasma membrane sub-domain and associated integral transmembrane proteins, and the proteins (eisosome filaments) that form a scaffolding lattice on the cytoplasmic face.
70942	neutrophil mediated cytotoxicity	P	The directed killing of a target cell by a neutrophil.
70943	neutrophil mediated killing of symbiont cell	P	The directed killing of a symbiont target cell by a neutrophil.
70944	neutrophil mediated killing of bacterium	P	The directed killing of a bacterium by a neutrophil.
70945	neutrophil mediated killing of gram-negative bacterium	P	The directed killing of a gram-negative bacterium by a neutrophil.
70946	neutrophil mediated killing of gram-positive bacterium	P	The directed killing of a gram-positive bacterium by a neutrophil.
70947	neutrophil mediated killing of fungus	P	The directed killing of a fungal cell by a neutrophil.
70948	regulation of neutrophil mediated cytotoxicity	P	Any process that modulates the rate, frequency or extent of neutrophil mediated killing of a target cell, the directed killing of a target cell by a neutrophil.
70949	regulation of neutrophil mediated killing of symbiont cell	P	Any process that modulates the rate, frequency or extent of neutrophil mediated killing of a symbiont cell, the directed killing of a symbiont target cell by a neutrophil.
70950	regulation of neutrophil mediated killing of bacterium	P	Any process that modulates the rate, frequency or extent of neutrophil mediated killing of a bacterium, the directed killing of a bacterium by a neutrophil.
70951	regulation of neutrophil mediated killing of gram-negative bacterium	P	Any process that modulates the rate, frequency or extent of neutrophil mediated killing of a gram-negative bacterium, the directed killing of a gram-negative bacterium by a neutrophil.
70952	regulation of neutrophil mediated killing of gram-positive bacterium	P	Any process that modulates the rate, frequency or extent of neutrophil mediated killing of a gram-positive bacterium, the directed killing of a gram-positive bacterium by a neutrophil.
70953	regulation of neutrophil mediated killing of fungus	P	Any process that modulates the rate, frequency or extent of neutrophil mediated killing of a fungal cell, the directed killing of a fungal cell by a neutrophil.
70954	negative regulation of neutrophil mediated cytotoxicity	P	Any process that decreases the frequency, rate or extent of the directed killing of a target cell by a neutrophil.
70955	negative regulation of neutrophil mediated killing of symbiont cell	P	Any process that decreases the frequency, rate or extent of the directed killing of a symbiont target cell by a neutrophil.
70956	negative regulation of neutrophil mediated killing of bacterium	P	Any process that decreases the frequency, rate or extent of the directed killing of a bacterium by a neutrophil.
70957	negative regulation of neutrophil mediated killing of gram-negative bacterium	P	Any process that decreases the frequency, rate or extent of the directed killing of a gram-negative bacterium by a neutrophil.
70958	negative regulation of neutrophil mediated killing of gram-positive bacterium	P	Any process that decreases the frequency, rate or extent of the directed killing of a gram-positive bacterium by a neutrophil.
70959	negative regulation of neutrophil mediated killing of fungus	P	Any process that decreases the frequency, rate or extent of the directed killing of a fungal cell by a neutrophil.
70960	positive regulation of neutrophil mediated cytotoxicity	P	Any process that increases the frequency, rate or extent of the directed killing of a target cell by a neutrophil.
70961	positive regulation of neutrophil mediated killing of symbiont cell	P	Any process that increases the frequency, rate or extent of the directed killing of a symbiont target cell by a neutrophil.
70962	positive regulation of neutrophil mediated killing of bacterium	P	Any process that increases the frequency, rate or extent of the directed killing of a bacterium by a neutrophil.
70963	positive regulation of neutrophil mediated killing of gram-negative bacterium	P	Any process that increases the frequency, rate or extent of the directed killing of a gram-negative bacterium by a neutrophil.
70964	positive regulation of neutrophil mediated killing of gram-positive bacterium	P	Any process that increases the frequency, rate or extent of the directed killing of a gram-positive bacterium by a neutrophil.
70965	positive regulation of neutrophil mediated killing of fungus	P	Any process that increases the frequency, rate or extent of the directed killing of a fungal cell by a neutrophil.
70966	nuclear-transcribed mRNA catabolic process, no-go decay	P	The chemical reactions and pathways resulting in the breakdown of the transcript body of a nuclear-transcribed mRNA with stalls in translation elongation.
70967	coenzyme F420 binding	F	Interacting selectively and non-covalently with F420, the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes.
70968	pyrroloquinoline quinone binding	F	Interacting selectively and non-covalently with pyrroloquinoline quinone, PQQ, the coenzyme or the prosthetic group of certain alcohol dehydrogenases and glucose dehydrogenases.
70970	interleukin-2 secretion	P	The regulated release of interleukin-2 from a cell.
70971	endoplasmic reticulum exit site	C	An endoplasmic reticulum part at which COPII-coated vesicles are produced.
70972	protein localization to endoplasmic reticulum	P	A process in which a protein is transported to, or maintained in, a location within the endoplasmic reticulum.
70973	protein localization to endoplasmic reticulum exit site	P	A process in which a protein is transported to, or maintained in, a location at an endoplasmic reticulum exit site.
70974	POU domain binding	F	Interacting selectively and non-covalently with a POU domain of a protein. The POU domain is a bipartite DNA binding domain composed of two subunits separated by a non-conserved region of 15-55 amino acids; it is found in several eukaryotic transcription factors.
70975	FHA domain binding	F	Interacting selectively and non-covalently with a FHA domain of a protein. The FHA domain is a phosphopeptide recognition domain found in many regulatory proteins, and consists of approximately 80-100 amino acid residues folded into an 11-stranded beta sandwich.
70976	TIR domain binding	F	Interacting selectively and non-covalently with a Toll-Interleukin receptor (TIR) domain of a protein. The TIR domain is an intracellular 200 residue domain that is found in the Toll protein, the interleukin-1 receptor (IL-1R), and MyD88; it contains three highly-conserved regions, and mediates protein-protein interactions between the Toll-like receptors (TLRs) and signal-transduction components.
70977	bone maturation	P	A developmental process, independent of morphogenetic (shape) change, that is required for bone to attain its fully functional state.
70978	voltage-gated calcium channel complex assembly	P	Cellular protein complex assembly that results in the formation of a voltage-gated calcium channel complex.
70979	protein K11-linked ubiquitination	P	A protein ubiquitination process in which ubiquitin monomers are attached to a protein, and then ubiquitin polymers are formed by linkages between lysine residues at position 11 of the ubiquitin monomers. K11-linked polyubiquitination targets the substrate protein for degradation. The anaphase-promoting complex promotes the degradation of mitotic regulators by assembling K11-linked polyubiquitin chains.
70980	biphenyl catabolic process	P	The chemical reactions and pathways resulting in the breakdown of biphenyl, a toxic aromatic hydrocarbon used as a heat transfer agent, as a fungistat in packaging citrus fruits and in plant disease control. Biphenyl can be chlorinated with 1-10 chlorine molecules to form polychlorinated biphenyls (PCBs).
70981	L-asparagine biosynthetic process	P	The chemical reactions and pathways resulting in the formation of asparagine, (2S)-2-amino-3-carbamoylpropanoic acid.
70982	L-asparagine metabolic process	P	The chemical reactions and pathways involving L-asparagine, (2S)-2-amino-3-carbamoylpropanoic acid.
70983	dendrite guidance	P	The process in which the migration of a dendrite is directed to a specific target site in response to a combination of attractive and repulsive cues.
70984	SET domain binding	F	Interacting selectively and non-covalently with a SET domain of a protein. SET domains are named after three Drosophila proteins that contain this domain: Su(var), E(z) and trithorax. SET domains are associated with histone lysine methylation.
70985	TFIIK complex	C	A transcription factor complex that forms part of the holo TFIIH complex. In Saccharomyces/human, TFIIK contains Ccl1p/Cyclin H, Tfb3p/MAT1 and Kin2p/CDK7.
70986	left/right axis specification	P	The establishment, maintenance and elaboration of the left/right axis. The left/right axis is defined by a line that runs orthogonal to both the anterior/posterior and dorsal/ventral axes. Each side is defined from the viewpoint of the organism rather of the observer (as per anatomical axes).
70987	error-free translesion synthesis	P	The conversion of DNA-damage induced single-stranded gaps into large molecular weight DNA after replication by using a specialized DNA polymerase or replication complex to insert a defined nucleotide across the lesion. This process does not remove the replication-blocking lesions but does not causes an increase in the endogenous mutation level. For S. cerevisiae, RAD30 encodes DNA polymerase eta, which incorporates two adenines. When incorporated across a thymine-thymine dimer, it does not increase the endogenous mutation level.
70988	demethylation	P	The process of removing one or more methyl groups from a molecule.
70989	oxidative demethylation	P	The process of removing one or more methyl groups from a molecule, involving the oxidation (i.e. electron loss) of one or more atoms in the substrate.
70990	snRNP binding	F	Interacting selectively and non-covalently with any part of a small nuclear ribonucleoprotein particle.
70991	medium-chain-acyl-CoA dehydrogenase activity	F	Catalysis of the reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor, where the acyl group is a medium-chain fatty acid residue. A medium chain fatty acid is any fatty acid with a chain length of between C6 and C12.
70992	translation initiation complex	C	A ribonucleoprotein complex that contains a ribosome, mRNA, and initiator tRNA; the functional ribosome is at the AUG, with the methionyl/formyl-methionyl-tRNA positioned at the P site.
70993	translation preinitiation complex	C	A ribonucleoprotein complex that contains the small ribosomal subunit, a translation initiation ternary complex (i.e. an initiator tRNA, GTP, and an IF2 or eIF2 complex), and an mRNA.
70994	detection of oxidative stress	P	The series of events in which a stimulus indicating oxidative stress is received and converted into a molecular signal.
70995	NADPH oxidation	P	A metabolic process that results in the oxidation of reduced nicotinamide adenine dinucleotide, NADPH, to the oxidized form, NADP.
70996	type 1 melanocortin receptor binding	F	Interacting selectively and non-covalently with a type 1 melanocortin receptor.
70997	neuron death	P	The process of cell death in a neuron.
70998	sensory perception of gravity	P	The series of events required for an organism to receive a gravitational stimulus, convert it to a molecular signal, and recognize and characterize the signal. This is a neurological process.
70999	detection of mechanical stimulus involved in sensory perception of gravity	P	The series of events involved in the perception of gravity in which a sensory mechanical stimulus is received and converted into a molecular signal.
71000	response to magnetism	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a magnetic stimulus.
71001	U4/U6 snRNP	C	A ribonucleoprotein complex that contains base-paired U4 and U6 small nuclear RNAs.
71002	U4atac/U6atac snRNP	C	A ribonucleoprotein complex that contains base-paired U4atac and U6atac small nuclear RNAs.
71003	penta-snRNP complex	C	A ribonucleoprotein complex formed by the association of the U1, U2, U4/U6 and U5 small nuclear ribonucleoproteins.
71004	U2-type prespliceosome	C	A spliceosomal complex that is formed by association of the 5' splice site with the U1 snRNP, while the branch point sequence is recognized by the U2 snRNP. The prespliceosome includes many proteins in addition to those found in the U1 and U2 snRNPs. Commitment to a given pair of 5' and 3' splice sites occurs at the time of prespliceosome formation.
71005	U2-type precatalytic spliceosome	C	A spliceosomal complex that is formed by the recruitment of the preassembled U4/U6.U5 tri-snRNP to the prespliceosome. Although all 5 snRNPs are present, the precatalytic spliceosome is catalytically inactive. The precatalytic spliceosome includes many proteins in addition to those found in the U1, U2 and U4/U6.U5 snRNPs.
71006	U2-type catalytic step 1 spliceosome	C	A spliceosomal complex that is formed by the displacement of the U1 and U4 snRNPs from the precatalytic spliceosome; the U2, U5 and U6 snRNPs remain associated with the mRNA. This complex, sometimes called the activated spliceosome, is the catalytically active form of the spliceosome, and includes many proteins in addition to those found in the U2, and U5 and U6 snRNPs.
71007	U2-type catalytic step 2 spliceosome	C	A spliceosomal complex that contains the U2, U5 and U6 snRNPs bound to a splicing intermediate in which the first catalytic cleavage of the 5' splice site has occurred. The precise subunit composition differs significantly from that of the catalytic step 1, or activated, spliceosome, and includes many proteins in addition to those found in the U2, U5 and U6 snRNPs.
71008	U2-type post-mRNA release spliceosomal complex	C	A spliceosomal complex that is formed following the release of the spliced product from the post-spliceosomal complex and contains the excised intron and the U2, U5 and U6 snRNPs.
71009	U4atac/U6atac x U5 tri-snRNP complex	C	A ribonucleoprotein complex formed by the association of the U4atac/U6atac and U5 small nuclear ribonucleoproteins.
71010	prespliceosome	C	A spliceosomal complex that is formed by association of the 5' splice site and the branch point sequence with specific snRNPs. The prespliceosome includes many proteins in addition to those found in the bound snRNPs. Commitment to a given pair of 5' and 3' splice sites occurs at the time of prespliceosome formation. Prespliceosome complexes are not active for splicing, but are instead an early step in the assembly of a spliceosomal complex.
71011	precatalytic spliceosome	C	A spliceosomal complex that is formed by the recruitment of a preassembled U5-containing tri-snRNP to the prespliceosome. Although all 5 snRNPs are present, the precatalytic spliceosome is catalytically inactive. The precatalytic spliceosome includes many proteins in addition to those found in the associated snRNPs.
71012	catalytic step 1 spliceosome	C	A spliceosomal complex that is formed by the displacement of the two snRNPs from the precatalytic spliceosome; three snRNPs including U5 remain associated with the mRNA. This complex, sometimes called the activated spliceosome, is the catalytically active form of the spliceosome, and includes many proteins in addition to those found in the associated snRNPs.
71013	catalytic step 2 spliceosome	C	A spliceosomal complex that contains three snRNPs, including U5, bound to a splicing intermediate in which the first catalytic cleavage of the 5' splice site has occurred. The precise subunit composition differs significantly from that of the catalytic step 1, or activated, spliceosome, and includes many proteins in addition to those found in the associated snRNPs.
71014	post-mRNA release spliceosomal complex	C	A spliceosomal complex that is formed following the release of the spliced product from the post-spliceosomal complex and contains the excised intron and three snRNPs, including U5.
71015	U12-type prespliceosome	C	A spliceosomal complex that is formed by the cooperative binding of the heterodimeric U11/U12 snRNP to the 5' splice site and the branch point sequence. The U12-type prespliceosome includes many proteins in addition to those found in the U11/U12 heterodimeric snRNPs. Commitment to a given pair of 5' and 3' splice sites occurs at the time of prespliceosome formation.
71016	U12-type precatalytic spliceosome	C	A spliceosomal complex that is formed by the recruitment of the preassembled U4atac/U6atac.U5 tri-snRNP to the U12-type prespliceosome. Although all 5 snRNPs are present, the precatalytic spliceosome is catalytically inactive. The precatalytic spliceosome includes many proteins in addition to those found in the U11, U12 and U4atac/U6atac.U5 snRNPs.
71017	U12-type catalytic step 1 spliceosome	C	A spliceosomal complex that is formed by the displacement of the U11 and U4atac snRNPs from the precatalytic spliceosome; the U12, U5 and U6atac snRNPs remain associated with the mRNA. This complex, sometimes called the activated spliceosome, is the catalytically active form of the spliceosome, and includes many proteins in addition to those found in the U12, and U5 and U6atac snRNPs.
71018	U12-type catalytic step 2 spliceosome	C	A spliceosomal complex that contains the U12, U5 and U6atac snRNPs bound to a splicing intermediate in which the first catalytic cleavage of the 5' splice site has occurred. The precise subunit composition differs significantly from that of the catalytic step 1, or activated, spliceosome, and includes many proteins in addition to those found in the U12, U5 and U6atac snRNPs.
71019	U12-type post-mRNA release spliceosomal complex	C	A spliceosomal complex that is formed following the release of the spliced product from the post-spliceosomal complex and contains the excised intron and the U12, U5 and U6atac snRNPs.
71020	post-spliceosomal complex	C	A spliceosomal complex that is formed following the second splicing event and contains the spliced product, the excised intron, and three snRNPs, including U5.
71021	U2-type post-spliceosomal complex	C	A spliceosomal complex that is formed following the second splicing event and contains the spliced product, the excised intron, and three snRNPs, U5, U2 and U6.
71022	U12-type post-spliceosomal complex	C	A spliceosomal complex that is formed following the second splicing event and contains the spliced product, the excised intron, and three snRNPs, U5, U12 and U6atac.
71023	trans spliceosomal complex	C	A spliceosomal complex that forms during the addition of a specific spliced leader (SL) sequence to the 5'-end of a messenger RNA primary transcript, a process which occurs in a number of eukaryotic organisms, including trypanosomatid protozoans, euglenoids, nematodes, trematodes, and chordates.
71024	SL snRNP	C	A ribonucleoprotein complex that contains spliced leader (SL) RNA.
71025	RNA surveillance	P	The set of processes involved in identifying and degrading defective or aberrant RNAs.
71026	cytoplasmic RNA surveillance	P	The set of processes involved in identifying and degrading defective or aberrant RNAs within the cytoplasm.
71027	nuclear RNA surveillance	P	The set of processes involved in identifying and degrading defective or aberrant RNAs within the nucleus.
71028	nuclear mRNA surveillance	P	The set of processes involved in identifying and degrading defective or aberrant mRNAs within the nucleus.
71029	nuclear ncRNA surveillance	P	The set of processes involved in identifying and degrading defective or aberrant ncRNAs within the nucleus.
71030	nuclear mRNA surveillance of spliceosomal pre-mRNA splicing	P	The set of processes involved in identifying and degrading incorrectly spliced pre-mRNAs within the nucleus.
71031	nuclear mRNA surveillance of mRNA 3'-end processing	P	The set of processes involved in identifying and degrading mRNAs with incorrectly formed 3'-ends within the nucleus.
71032	nuclear mRNA surveillance of mRNP export	P	The set of processes involved in identifying and degrading incorrectly formed or aberrant nuclear mRNPs docked at the nuclear pore complex prior to export to the cytoplasm.
71033	nuclear retention of pre-mRNA at the site of transcription	P	The process involved in retention of aberrant or improperly formed mRNAs, e.g. those that are incorrectly or incompletely spliced or that have incorrectly formed 3'-ends, within the nucleus at the site of transcription.
71034	CUT catabolic process	P	The chemical reactions and pathways resulting in the breakdown of cryptic unstable transcripts (CUTs).
71035	nuclear polyadenylation-dependent rRNA catabolic process	P	The chemical reactions and pathways occurring in the nucleus and resulting in the breakdown of a ribosomal RNA (rRNA) molecule, including RNA fragments released as part of processing the primary transcript into multiple mature rRNA species, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target rRNA.
71036	nuclear polyadenylation-dependent snoRNA catabolic process	P	The chemical reactions and pathways occurring in the nucleus and resulting in the breakdown of a small nucleolar RNA (snoRNA) molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target snoRNA.
71037	nuclear polyadenylation-dependent snRNA catabolic process	P	The chemical reactions and pathways occurring in the nucleus and resulting in the breakdown of a small nuclear RNA (snRNA) molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target snRNA.
71038	nuclear polyadenylation-dependent tRNA catabolic process	P	The chemical reactions and pathways occurring in the nucleus and resulting in the breakdown of an aberrant or incorrectly modified transfer RNA (tRNA) molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target tRNA.
71039	nuclear polyadenylation-dependent CUT catabolic process	P	The chemical reactions and pathways occurring in the nucleus and resulting in the breakdown of a cryptic unstable transcript (CUT), initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target CUT.
71040	nuclear polyadenylation-dependent antisense transcript catabolic process	P	The chemical reactions and pathways occurring in the nucleus and resulting in the breakdown of an antisense transcript, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target antisense transcript.
71041	antisense RNA transcript catabolic process	P	The chemical reactions and pathways resulting in the breakdown of antisense transcripts, i.e. transcripts that were produced from the antisense strand of a gene that produces a gene product and which often have a regulatory effect on the transcription of that gene product.
71042	nuclear polyadenylation-dependent mRNA catabolic process	P	The chemical reactions and pathways occurring in the nucleus and resulting in the breakdown of a messenger RNA (mRNA) molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target mRNA.
71043	CUT metabolic process	P	The chemical reactions and pathways involving cryptic unstable transcripts (CUTs), which are transcribed from intergenic regions. Many intergenic regions are heavily transcribed, but the transcripts are rarely detected due to rapid degradation by the nuclear exosome.
71044	histone mRNA catabolic process	P	The chemical reactions and pathways resulting in the breakdown of histone messenger RNA (mRNA).
71045	nuclear histone mRNA catabolic process	P	The chemical reactions and pathways resulting in the breakdown of histone messenger RNA (mRNA) within the nucleus.
71046	nuclear polyadenylation-dependent ncRNA catabolic process	P	The chemical reactions and pathways occurring in the nucleus and resulting in the breakdown of a noncoding RNA (ncRNA) molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target ncRNA.
71047	polyadenylation-dependent mRNA catabolic process	P	The chemical reactions and pathways resulting in the breakdown of a messenger RNA (mRNA) molecule, initiated by the enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end the target mRNA.
71048	nuclear retention of unspliced pre-mRNA at the site of transcription	P	The process involved in retention of incorrectly or incompletely spliced pre-mRNA within the nucleus at the site of transcription.
71049	nuclear retention of pre-mRNA with aberrant 3'-ends at the site of transcription	P	The process involved in retention of mRNAs that have incorrectly formed 3'-ends within the nucleus at the site of transcription.
71050	snoRNA polyadenylation	P	The enzymatic addition of a sequence of adenylyl residues at the 3' end of snoRNA molecule. In eukaryotes, this occurs in conjunction with termination of transcription of precursor snoRNA molecules and may occur post-transcriptionally on incorrectly processed molecules targeted for degradation.
71051	polyadenylation-dependent snoRNA 3'-end processing	P	Any process involved in forming the mature 3' end of a snoRNA molecule linked to prior polyadenylation of the 3'-end of the precursor snoRNA.
71052	alpha9-beta1 integrin-ADAM1 complex	C	A protein complex that consists of an alpha9-beta1 integrin complex bound to the transmembrane metallopeptidase ADAM1.
71053	alpha9-beta1 integrin-ADAM2 complex	C	A protein complex that consists of an alpha9-beta1 integrin complex bound to the transmembrane metallopeptidase ADAM2.
71054	alpha9-beta1 integrin-ADAM3 complex	C	A protein complex that consists of an alpha9-beta1 integrin complex bound to the transmembrane metallopeptidase ADAM3.
71055	alpha9-beta1 integrin-ADAM9 complex	C	A protein complex that consists of an alpha9-beta1 integrin complex bound to the transmembrane metallopeptidase ADAM9.
71056	alpha9-beta1 integrin-ADAM15 complex	C	A protein complex that consists of an alpha9-beta1 integrin complex bound to the transmembrane metallopeptidase ADAM15.
71057	alphav-beta3 integrin-ADAM15 complex	C	A protein complex that consists of an alphav-beta3 integrin complex bound to the transmembrane metallopeptidase ADAM15.
71058	alpha3-beta1 integrin-CD151 complex	C	A protein complex that consists of an alpha3-beta1 integrin complex bound to the tetraspanin CD151.
71059	alpha6-beta1 integrin-CD151 complex	C	A protein complex that consists of an alpha6-beta1 integrin complex bound to the tetraspanin CD151.
71060	alpha7-beta1 integrin-CD151 complex	C	A protein complex that consists of an alpha7-beta1 integrin complex bound to the tetraspanin CD151.
71061	alpha6-beta4 integrin-CD151 complex	C	A protein complex that consists of an alpha6-beta4 integrin complex bound to the tetraspanin CD151.
71062	alphav-beta3 integrin-vitronectin complex	C	A protein complex that consists of an alphav-beta3 integrin complex bound to vitronectin.
71063	sensory perception of wind	P	The series of events required for an organism to receive sensory mechanical stimulus resulting from air flow, convert it to a molecular signal, and recognize and characterize the signal.
71064	alphaE-beta7 integrin-E-cadherin complex	C	A protein complex that consists of an alphaE-beta7 integrin complex bound to E-cadherin.
71065	alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex	C	A protein complex that consists of an alpha9-beta1 integrin complex bound to vascular cell adhesion molecule-1.
71066	detection of mechanical stimulus involved in sensory perception of wind	P	The series of events involved in the perception of wind in which a mechanical stimulus is received and converted into a molecular signal.
71067	alphav-beta3 integrin-ADAM23 complex	C	A protein complex that consists of an alphav-beta3 integrin complex bound to the transmembrane metallopeptidase ADAM23.
71068	alpha9-beta1 integrin-ADAM12 complex	C	A protein complex that consists of an alpha9-beta1 integrin complex bound to the transmembrane metallopeptidase ADAM12.
71069	alpha4-beta1 integrin-thrombospondin-1 complex	C	A protein complex that consists of an alpha4-beta1 integrin complex bound to thrombospondin-1.
71070	alpha4-beta1 integrin-thrombospondin-2 complex	C	A protein complex that consists of an alpha4-beta1 integrin complex bound to thrombospondin-2.
71071	regulation of phospholipid biosynthetic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of phospholipids.
71072	negative regulation of phospholipid biosynthetic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of phospholipids.
71073	positive regulation of phospholipid biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of phospholipids.
71074	eukaryotic initiation factor eIF2 binding	F	Interacting selectively and non-covalently with eukaryotic initiation factor eIF2, a protein complex involved in the initiation of ribosome-mediated translation.
71075	CUGBP1-eIF2 complex	C	A protein complex that contains the eukaryotic translation initiation factor 2 complex (EIF2), CUG binding protein 1, and several endoplasmic reticulum proteins; the complex is involved in the regulation of translation.
71076	RNA 3' uridylation	P	The enzymatic addition of a sequence of uridylyl residues at the 3' end of an RNA molecule.
71077	adenosine 3',5'-bisphosphate transmembrane transporter activity	F	Enables the transfer of adenosine 3',5'-bisphosphate from one side of a membrane to the other.
71078	fibronectin-tissue transglutaminase complex	C	A protein complex that consists of fibronectin bound to tissue transglutaminase, and is involved in cell adhesion.
71079	alpha2-beta1 integrin-chondroadherin complex	C	A protein complex that consists of an alpha2-beta1 integrin complex bound to the cartilage matrix protein chondroadherin.
71080	alpha3-beta1 integrin-basigin complex	C	A protein complex that consists of an alpha3-beta1 integrin complex bound to the cell surface protein basigin.
71081	alpha3-beta1 integrin-CD63 complex	C	A protein complex that consists of an alpha3-beta1 integrin complex bound to the tetraspanin CD63.
71082	alpha9-beta1 integrin-tenascin complex	C	A protein complex that consists of an alpha9-beta1 integrin complex bound to the extracellular matrix protein tenascin.
71083	alphaV-beta3 integrin-CD47-FCER2 complex	C	A protein complex that consists of an alphaV-beta3 integrin complex bound to the cell surface protein CD47 and the low-affinity immunoglobulin epsilon Fc receptor (FCER2).
71084	alpha2-beta1 integrin-CD47 complex	C	A protein complex that consists of an alpha2-beta1 integrin complex bound to the cell surface protein CD47.
71085	alphaIIb-beta3 integrin-CD9 complex	C	A protein complex that consists of an alphaIIb-beta3 integrin complex bound to the cell surface protein CD9.
71086	alphaIIb-beta3 integrin-CD9-CD47-platelet glycoprotein Ib complex	C	A protein complex that consists of an alphaIIb-beta3 integrin complex bound to the cell surface proteins CD9 and CD47, and the heterodimeric platelet glycoprotein Ib.
71087	alpha11-beta1 integrin-collagen type I complex	C	A protein complex that consists of an alpha11-beta1 integrin complex bound to a type I collagen.
71088	alpha5-beta1 integrin-tissue transglutaminase complex	C	A protein complex that consists of an alpha5-beta1 integrin complex bound to tissue transglutaminase.
71089	alphaV-beta3 integrin-tissue transglutaminase complex	C	A protein complex that consists of an alphaV-beta3 integrin complex bound to tissue transglutaminase.
71090	alphaIIb-beta3 integrin-fibronectin-tissue transglutaminase complex	C	A protein complex that consists of an alphaIIb-beta3 integrin complex bound to fibronectin and tissue transglutaminase.
71091	alpha1-beta1 integrin-tissue transglutaminase complex	C	A protein complex that consists of an alpha1-beta1 integrin complex bound to tissue transglutaminase.
71092	alpha3-beta1 integrin-tissue transglutaminase complex	C	A protein complex that consists of an alpha3-beta1 integrin complex bound to tissue transglutaminase.
71093	alpha5-beta1 integrin-fibronectin-tissue transglutaminase complex	C	A protein complex that consists of an alpha5-beta1 integrin complex bound to fibronectin and tissue transglutaminase.
71094	alpha6-beta4 integrin-CD9 complex	C	A protein complex that consists of an alpha6-beta4 integrin complex bound to the cell surface protein CD9.
71095	alpha3-beta1 integrin-thrombospondin complex	C	A protein complex that consists of an alpha3-beta1 integrin complex bound to thrombospondin.
71096	alphaV-beta3 integrin-gelsolin complex	C	A protein complex that consists of an alphaV-beta3 integrin complex bound to gelsolin.
71097	alphaV-beta3 integrin-paxillin-Pyk2 complex	C	A protein complex that consists of an alphaV-beta3 integrin complex bound to paxillin and the FAK-related kinase Pyk2.
71098	alpha6-beta4 integrin-Fyn complex	C	A protein complex that consists of an alpha6-beta4 integrin complex bound to the Src family tyrosine kinase Fyn.
71099	alphaV-beta6 integrin-TGFbeta-3 complex	C	A protein complex that consists of an alphaV-beta6 integrin complex bound to transforming growth factor beta-3 (TGFbeta-3).
71100	alphaV-beta8 integrin-MMP14-TGFbeta-1 complex	C	A protein complex that consists of an alphaV-beta8 integrin complex bound to matrix metalloproteinase 14 and transforming growth factor beta-1 (TGFbeta-1).
71101	alpha4-beta1 integrin-JAM2 complex	C	A protein complex that consists of an alpha4-beta1 integrin complex bound to the cell adhesion molecule JAM2.
71102	alpha4-beta1 integrin-paxillin complex	C	A protein complex that consists of an alpha4-beta1 integrin complex bound to paxillin.
71103	DNA conformation change	P	A cellular process that results in a change in the spatial configuration of a DNA molecule. A conformation change can bend DNA, or alter the, twist, writhe, or linking number of a DNA molecule.
71104	response to interleukin-9	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-9 stimulus.
71105	response to interleukin-11	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-11 stimulus.
71106	adenosine 3',5'-bisphosphate transmembrane transport	P	The directed movement of adenosine 3',5'-bisphosphate across a membrane into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
71107	response to parathyroid hormone	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a parathyroid hormone stimulus.
71108	protein K48-linked deubiquitination	P	A protein deubiquitination process in which a K48-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 48 of the ubiquitin monomers, is removed from a protein.
71109	superior temporal gyrus development	P	The process whose specific outcome is the progression of the superior temporal gyrus over time, from its formation to the mature structure. The superior temporal gyrus is a portion of the cerebral cortex that extends from the lateral sulcus to the superior temporal sulcus.
71110	histone biotinylation	P	The modification of a histone by the addition of a biotinyl group.
71111	cyclic-guanylate-specific phosphodiesterase activity	F	Catalysis of the reaction: cyclic di-3',5'-guanylate + H(2)O = 5'-phosphoguanylyl(3'->5')guanosine + H(+).
71112	alpha4-beta4 integrin-EMILIN-1 complex	C	A protein complex that consists of an alpha4-beta4 integrin complex bound to EMILIN-1 (ElastinMicrofibril Interface Located ProteIN).
71113	alphaIIb-beta3 integrin-ICAM-4 complex	C	A protein complex that consists of an alphaIIb-beta3 integrin complex bound to the cell adhesion molecule ICAM-4.
71114	alphaV-beta3 integrin-tumstatin complex	C	A protein complex that consists of an alphaV-beta3 integrin complex bound to tumstatin, the NC1 domain of the alpha3 chain of type IV collagen.
71115	alpha5-beta1 integrin-endostatin complex	C	A protein complex that consists of an alpha5-beta1 integrin complex bound to endostatin, the NC1 domain of the alpha1 chain of type XVIII collagen.
71116	alpha6-beta1 integrin-CYR61 complex	C	A protein complex that consists of an alpha6-beta1 integrin complex bound to CYR61, a cysteine-rich protein involved in angiogenesis.
71117	alpha5-beta1 integrin-fibronectin-NOV complex	C	A protein complex that consists of an alpha5-beta1 integrin complex bound to fibronectin and the extracellular matrix protein NOV.
71118	alphaV-beta3 integrin-NOV complex	C	A protein complex that consists of an alphaV-beta3 integrin complex bound to the extracellular matrix protein NOV.
71119	alpha7-beta1 integrin-nicotinamide riboside kinase complex	C	A protein complex that consists of an alpha7-beta1 integrin complex bound to nicotinamide riboside kinase 2 (also known as muscle integrin binding protein, MIBP).
71120	alpha4-beta1 integrin-CD47 complex	C	A protein complex that consists of an alpha4-beta1 integrin complex bound to the cell surface antigen CD47.
71121	alpha9-beta1 integrin-VEGF-D complex	C	A protein complex that consists of an alpha9-beta1 integrin complex bound to vascular endothelial growth factor D.
71122	alpha9-beta1 integrin-VEGF-A complex	C	A protein complex that consists of an alpha9-beta1 integrin complex bound to vascular endothelial growth factor A.
71123	alpha9-beta1 integrin-VEGF-C complex	C	A protein complex that consists of an alpha9-beta1 integrin complex bound to vascular endothelial growth factor C.
71124	alpha1-beta1 integrin-tyrosine-protein phosphatase non-receptor type 2 complex	C	A protein complex that consists of an alpha1-beta1 integrin complex bound to tyrosine-protein phosphatase non-receptor type 2.
71125	alphaV-beta3 integrin-EGFR complex	C	A protein complex that consists of an alphaV-beta3 integrin complex bound to epidermal growth factor receptor.
71126	alphaV-beta6 integrin-osteopontin complex	C	A protein complex that consists of an alphaV-beta6 integrin complex bound to osteopontin.
71127	alpha9-beta1 integrin-osteopontin complex	C	A protein complex that consists of an alpha9-beta1 integrin complex bound to osteopontin.
71128	alpha5-beta1 integrin-osteopontin complex	C	A protein complex that consists of an alpha5-beta1 integrin complex bound to osteopontin.
71129	alphaV-beta3 integrin-LPP3 complex	C	A protein complex that consists of an alphaV-beta3 integrin complex bound to lipid phosphate phosphohydrolase-3.
71130	alpha5-beta1 integrin-LPP3 complex	C	A protein complex that consists of an alpha5-beta1 integrin complex bound to lipid phosphate phosphohydrolase-3.
71131	alphaV-beta3 integrin-laminin alpha-4 complex	C	A protein complex that consists of an alphaV-beta3 integrin complex bound to laminin alpha-4.
71132	alphaX-beta2 integrin-ICAM-4 complex	C	A protein complex that consists of an alphaX-beta2 integrin complex bound to intercellular adhesion molecule 4.
71133	alpha9-beta1 integrin-ADAM8 complex	C	A protein complex that consists of an alpha9-beta1 integrin complex bound to the transmembrane metallopeptidase ADAM8.
71134	alpha9-beta1 integrin-thrombospondin-1 complex	C	A protein complex that consists of an alpha9-beta1 integrin complex bound to thrombospondin-1.
71135	alpha7-beta1 integrin-focal adhesion kinase complex	C	A protein complex that consists of an alpha7-beta1 integrin complex bound to focal adhesion kinase.
71136	alpha7-beta1 integrin-laminin alpha-2 complex	C	A protein complex that consists of an alpha7-beta1 integrin complex bound to laminin alpha-2.
71137	alphaV-beta3 integrin-CD98 complex	C	A protein complex that consists of an alphaV-beta3 integrin complex bound to the cell surface antigen CD98.
71138	alpha5-beta5-fibronectin-SFRP2 complex	C	A protein complex that consists of an alpha5-beta5 integrin complex bound to fibronectin and secreted frizzled-related protein 2.
71139	resolution of recombination intermediates	P	The cleavage and rejoining of intermediates, such as Holliday junctions, formed during DNA recombination to produce two intact molecules in which genetic material has been exchanged.
71140	resolution of mitotic recombination intermediates	P	The cleavage and rejoining of intermediates, mitotic recombination to produce two intact molecules in which genetic material has been exchanged.
71141	SMAD protein complex	C	A protein complex that consists of SMAD proteins; may be homomeric or heteromeric.
71142	SMAD2 protein complex	C	A protein complex that consists of a SMAD2 homotrimer.
71143	SMAD3 protein complex	C	A protein complex that consists of a SMAD3 homotrimer.
71144	SMAD2-SMAD3 protein complex	C	A heteromeric SMAD protein complex that contains SMAD2 and SMAD3.
71145	SMAD2-SMAD4 protein complex	C	A heteromeric SMAD protein complex that contains SMAD2 and SMAD4.
71146	SMAD3-SMAD4 protein complex	C	A heteromeric SMAD protein complex that contains SMAD3 and SMAD4.
71147	TEAD-2 multiprotein complex	C	A protein complex that consists of the DNA binding protein TEAD-2 bound to 12 other polypeptides including the transcriptional coactivator YAP, the multi-PDZ domain protein MPDZ (also called MUPP1), a 14-3-3 domain protein, and others.
71148	TEAD-1-YAP complex	C	A transcription factor complex that is composed of the DNA binding protein TEAD-1 and the transcriptional coactivator YAP.
71149	TEAD-2-YAP complex	C	A transcription factor complex that is composed of the DNA binding protein TEAD-2 and the transcriptional coactivator YAP.
71150	TEAD-3-YAP complex	C	A transcription factor complex that is composed of the DNA binding protein TEAD-3 and the transcriptional coactivator YAP.
71151	TEAD-4-YAP complex	C	A transcription factor complex that is composed of the DNA binding protein TEAD-4 and the transcriptional coactivator YAP.
71152	G-protein alpha(q)-synembrin complex	C	A protein complex formed by the association of the guanine nucleotide exchange factor synembrin with the alpha(q) subunit of a heterotrimeric G protein.
71153	G-protein alpha(o)-synembrin complex	C	A protein complex formed by the association of the guanine nucleotide exchange factor synembrin with the alpha(o) subunit of a heterotrimeric G protein.
71154	G-protein alpha(i)1-synembrin complex	C	A protein complex formed by the association of the guanine nucleotide exchange factor synembrin with the alpha(i)1 subunit of a heterotrimeric G protein.
71155	G-protein alpha(13)-synembrin complex	C	A protein complex formed by the association of the guanine nucleotide exchange factor synembrin with the alpha(13) subunit of a heterotrimeric G protein.
71156	regulation of cell cycle arrest	P	Any process that modulates the rate, frequency, or extent of cell cycle arrest, the process in which the cell cycle is halted during one of the normal phases.
71157	negative regulation of cell cycle arrest	P	Any process that decreases the rate, frequency, or extent of cell cycle arrest, the process in which the cell cycle is halted during one of the normal phases.
71158	positive regulation of cell cycle arrest	P	Any process that increases the rate, frequency, or extent of cell cycle arrest, the process in which the cell cycle is halted during one of the normal phases.
71159	NF-kappaB complex	C	A protein complex that consists of a homo- or heterodimer of members of a family of structurally related proteins that contain a conserved N-terminal region called the Rel homology domain (RHD). In the nucleus, NF-kappaB complexes act as transcription factors. In unstimulated cells, NF-kappaB dimers are sequestered in the cytoplasm by IkappaB monomers; signals that induce NF-kappaB activity cause degradation of IkappaB, allowing NF-kappaB dimers to translocate to the nucleus and induce gene expression.
71160	cyanophycin synthetase activity (L-aspartate-adding)	F	Catalysis of the reaction: ATP + [L-Asp(4-L-Arg)]n + L-Asp = ADP + phosphate + [L-Asp(4-L-Arg)]n-L-Asp.
71161	cyanophycin synthetase activity (L-arginine-adding)	F	Catalysis of the reaction: ATP + [L-Asp(4-L-Arg)]n-L-Asp + L-arginine = ADP + phosphate + [L-Asp(4-L-Arg)]n+1.
71162	CMG complex	C	A protein complex that contains the GINS complex, Cdc45p, and the heterohexameric MCM complex, and that is involved in unwinding DNA during replication.
71163	DNA replication preinitiation complex assembly	P	The aggregation, arrangement and bonding together of a set of components to form the DNA replication preinitiation complex, a protein-DNA complex that is assembled at eukaryotic DNA replication origins immediately prior to the initiation of DNA replication, by the assembly of additional proteins onto an existing prereplicative complex.
71164	RNA trimethylguanosine synthase activity	F	Catalysis of two successive methyl transfer reactions from AdoMet to the N-2 atom of guanosine, thereby converting 7-methylguanosine in an RNA cap to 2,2,7 trimethylguanosine.
71165	GINS complex assembly	P	The aggregation, arrangement and bonding together of a set of components to form a GINS complex, a heterotetrameric protein complex that associates with DNA replication origins and replication forks.
71166	ribonucleoprotein complex localization	P	Any process in which a ribonucleoprotein complex is transported to, or maintained in, a specific location within a cell.
71167	ribonucleoprotein complex import into nucleus	P	The directed movement of a ribonucleoprotein complex from the cytoplasm to the nucleus.
71168	protein localization to chromatin	P	Any process in which a protein is transported to, or maintained at, a part of a chromosome that is organized into chromatin.
71169	establishment of protein localization to chromatin	P	The directed movement of a protein to a part of a chromosome that is organized into chromatin.
71170	site-specific DNA replication termination	P	A DNA replication termination process that takes place at a specific termination site.
71171	site-specific DNA replication termination at RTS1 barrier	P	A DNA replication termination process that takes place at the RTS1 termination site in the mating type locus, in a specific direction required for subsequent imprinting and mating-type switching.
71172	dihydromonapterin reductase activity	F	Catalysis of the reaction: 7,8-dihydromonapterin + NADPH = tetrahydromonapterin + NADP+.
71173	spindle assembly checkpoint	P	A cell cycle checkpoint that delays the metaphase/anaphase transition until the spindle is correctly assembled and chromosomes are attached to the spindle.
71174	mitotic spindle checkpoint	P	A mitotic cell cycle checkpoint that originates from the spindle and delays the metaphase/anaphase transition of a mitotic nuclear division until the spindle is correctly assembled and oriented, the completion of anaphase until chromosomes are attached to the spindle, or mitotic exit and cytokinesis when the spindle does not form.
71175	MAML2-RBP-Jkappa-ICN1 complex	C	A protein complex that consists of the intracellular domain of Notch1 (ICN1), the DNA-binding transcription factor RBP-Jkappa, and the transcriptional coactivator Mastermind-like-2 (MAML2); the complex is involved in transcriptional activation in response to Notch-mediated signaling.
71176	MAML2-RBP-Jkappa-ICN2 complex	C	A protein complex that consists of the intracellular domain of Notch2 (ICN2), the DNA-binding transcription factor RBP-Jkappa, and the transcriptional coactivator Mastermind-like-2 (MAML2); the complex is involved in transcriptional activation in response to Notch-mediated signaling.
71177	MAML2-RBP-Jkappa-ICN3 complex	C	A protein complex that consists of the intracellular domain of Notch3 (ICN3), the DNA-binding transcription factor RBP-Jkappa, and the transcriptional coactivator Mastermind-like-2 (MAML2); the complex is involved in transcriptional activation in response to Notch-mediated signaling.
71178	MAML2-RBP-Jkappa-ICN4 complex	C	A protein complex that consists of the intracellular domain of Notch4 (ICN4), the DNA-binding transcription factor RBP-Jkappa, and the transcriptional coactivator Mastermind-like-2 (MAML2); the complex is involved in transcriptional activation in response to Notch-mediated signaling.
71179	MAML3-RBP-Jkappa-ICN1 complex	C	A protein complex that consists of the intracellular domain of Notch1 (ICN1), the DNA-binding transcription factor RBP-Jkappa, and the transcriptional coactivator Mastermind-like-3 (MAML3); the complex is involved in transcriptional activation in response to Notch-mediated signaling.
71180	MAML3-RBP-Jkappa-ICN2 complex	C	A protein complex that consists of the intracellular domain of Notch2 (ICN2), the DNA-binding transcription factor RBP-Jkappa, and the transcriptional coactivator Mastermind-like-3 (MAML3); the complex is involved in transcriptional activation in response to Notch-mediated signaling.
71181	MAML3-RBP-Jkappa-ICN3 complex	C	A protein complex that consists of the intracellular domain of Notch3 (ICN3), the DNA-binding transcription factor RBP-Jkappa, and the transcriptional coactivator Mastermind-like-3 (MAML3); the complex is involved in transcriptional activation in response to Notch-mediated signaling.
71182	MAML3-RBP-Jkappa-ICN4 complex	C	A protein complex that consists of the intracellular domain of Notch4 (ICN4), the DNA-binding transcription factor RBP-Jkappa, and the transcriptional coactivator Mastermind-like-3 (MAML3); the complex is involved in transcriptional activation in response to Notch-mediated signaling.
71183	protocadherin-alpha-protocadherin-gamma complex	C	A protein complex that contains two cell adhesion molecules, a protocadherin-alpha and a protocadherin-gamma, and is involved in the regulation of protein localization to the plasma membrane.
71184	protocadherin-alpha-v4-protocadherin-gamma-a1 complex	C	A protein complex that contains the cell adhesion molecules protocadherin-alpha-v4 and protocadherin-gamma-a1, and is involved in the regulation of protein localization to the plasma membrane.
71185	protocadherin-alpha-v4-protocadherin-gamma-a3 complex	C	A protein complex that contains the cell adhesion molecules protocadherin-alpha-v4 and protocadherin-gamma-a3, and is involved in the regulation of protein localization to the plasma membrane.
71186	protocadherin-alpha-v4-protocadherin-gamma-b2 complex	C	A protein complex that contains the cell adhesion molecules protocadherin-alpha-v4 and protocadherin-gamma-b2, and is involved in the regulation of protein localization to the plasma membrane.
71187	protocadherin-alpha-v4-protocadherin-gamma-b4 complex	C	A protein complex that contains the cell adhesion molecules protocadherin-alpha-v4 and protocadherin-gamma-b4, and is involved in the regulation of protein localization to the plasma membrane.
71188	protocadherin-alpha-v7-protocadherin-gamma-a1 complex	C	A protein complex that contains the cell adhesion molecules protocadherin-alpha-v7 and protocadherin-gamma-a1, and is involved in the regulation of protein localization to the plasma membrane.
71189	protocadherin-alpha-v7-protocadherin-gamma-a3 complex	C	A protein complex that contains the cell adhesion molecules protocadherin-alpha-v7 and protocadherin-gamma-a3, and is involved in the regulation of protein localization to the plasma membrane.
71190	protocadherin-alpha-v7-protocadherin-gamma-b2 complex	C	A protein complex that contains the cell adhesion molecules protocadherin-alpha-v7 and protocadherin-gamma-b2, and is involved in the regulation of protein localization to the plasma membrane.
71191	protocadherin-alpha-v7-protocadherin-gamma-b4 complex	C	A protein complex that contains the cell adhesion molecules protocadherin-alpha-v7 and protocadherin-gamma-b4, and is involved in the regulation of protein localization to the plasma membrane.
71192	Kv4.2-KChIP1 channel complex	C	A voltage-gated potassium channel complex that contains the Kv channel interacting protein KChIP1 associated with the channel via interaction with the Kv alpha subunit 4.2.
71193	Kv4.2-KChIP2 channel complex	C	A voltage-gated potassium channel complex that contains the Kv channel interacting protein KChIP2 associated with the channel via interaction with the Kv alpha subunit 4.2.
71194	Kv4.2-KChIP3 channel complex	C	A voltage-gated potassium channel complex that contains the Kv channel interacting protein KChIP3 associated with the channel via interaction with the Kv alpha subunit 4.2.
71195	Kv4.2-KChIP4 channel complex	C	A voltage-gated potassium channel complex that contains the Kv channel interacting protein KChIP4 associated with the channel via interaction with the Kv alpha subunit 4.2.
71196	Kv4.3-KChIP1 channel complex	C	A voltage-gated potassium channel complex that contains the Kv channel interacting protein KChIP1 associated with the channel via interaction with the Kv alpha subunit 4.3.
71197	Kv4.2-Kv4.3 channel complex	C	A voltage-gated potassium channel complex that contains the Kv alpha subunits 4.2 and 4.3.
71198	Kv4.1-DPP6 channel complex	C	A voltage-gated potassium channel complex that contains the peptidase-related protein DPP6 associated with the channel via interaction with the Kv alpha subunit 4.1.
71199	Kv4.1-DPP10 channel complex	C	A voltage-gated potassium channel complex that contains the peptidase-related protein DPP10 associated with the channel via interaction with the Kv alpha subunit 4.1.
71200	Kv4.2-DPP6 channel complex	C	A voltage-gated potassium channel complex that contains the peptidase-related protein DPP6 associated with the channel via interaction with the Kv alpha subunit 4.2.
71201	Kv4.3-DPP6 channel complex	C	A voltage-gated potassium channel complex that contains the peptidase-related protein DPP6 associated with the channel via interaction with the Kv alpha subunit 4.3.
71202	Kv4.3-DPP10 channel complex	C	A voltage-gated potassium channel complex that contains the peptidase-related protein DPP10 associated with the channel via interaction with the Kv alpha subunit 4.3.
71203	WASH complex	C	A protein complex that localizes at the surface of endosomes, where it recruits and activates the Arp2/3 complex to induce actin polymerization. In human, the WASH complex is composed of F-actin-capping protein subunits alpha and beta, WASH1, FAM21, KIAA1033, KIAA0196 and CCDC53.
71204	histone pre-mRNA 3'end processing complex	C	A ribonucleoprotein that binds to specific sites in, and is required for cleavage of, the 3'-end of histone pre-mRNAs. The complex contains the U7 snRNP and additional proteins, including the stem-loop binding protein (SLBP) and the exonuclease 3'hExo/Eri-1.
71205	protein localization to juxtaparanode region of axon	P	Any process in which a protein is transported to, or maintained at, the juxtaparanode region of an axon.
71206	establishment of protein localization to juxtaparanode region of axon	P	The directed movement of a protein to the juxtaparanode region of an axon.
71207	histone pre-mRNA stem-loop binding	F	Interacting selectively and non-covalently with a conserved stem-loop structure found in histone pre-mRNAs.
71208	histone pre-mRNA DCP binding	F	Interacting selectively and non-covalently with the downstream cleavage product (DCP) generated by histone pre-mRNA 3'-end processing.
71209	U7 snRNA binding	F	Interacting selectively and non-covalently with the U7 small nuclear RNA (U7 snRNA).
71210	protein insertion into membrane raft	P	The process in which a protein is incorporated into a membrane raft. Membrane rafts are small (10-200 nm), heterogeneous, highly dynamic, sterol- and sphingolipid-enriched membrane domains that compartmentalize cellular processes.
71211	protein targeting to vacuole involved in autophagy	P	The process of directing proteins towards the vacuole using signals contained within the protein, occurring as part of autophagy, the process in which cells digest parts of their own cytoplasm.
71212	subsynaptic reticulum	C	An elaborate tubulolamellar membrane system that underlies the postsynaptic cell membrane.
71213	cellular response to 1-aminocyclopropane-1-carboxylic acid	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 1-aminocyclopropane-1-carboxylic acid stimulus.
71214	cellular response to abiotic stimulus	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abiotic (non-living) stimulus.
71215	cellular response to abscisic acid stimulus	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abscisic acid stimulus.
71216	cellular response to biotic stimulus	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a biotic stimulus, a stimulus caused or produced by a living organism.
71217	cellular response to external biotic stimulus	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an external biotic stimulus, an external stimulus caused by, or produced by living things.
71218	cellular response to misfolded protein	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a misfolded protein stimulus.
71219	cellular response to molecule of bacterial origin	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by molecules of bacterial origin such as peptides derived from bacterial flagellin.
71220	cellular response to bacterial lipoprotein	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bacterial lipoprotein stimulus.
71221	cellular response to bacterial lipopeptide	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bacterial lipopeptide stimulus.
71222	cellular response to lipopolysaccharide	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipopolysaccharide stimulus; lipopolysaccharide is a major component of the cell wall of gram-negative bacteria.
71223	cellular response to lipoteichoic acid	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipoteichoic acid stimulus; lipoteichoic acid is a major component of the cell wall of gram-positive bacteria and typically consists of a chain of glycerol-phosphate repeating units linked to a glycolipid anchor.
71224	cellular response to peptidoglycan	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptidoglycan stimulus. Peptidoglycan is a bacterial cell wall macromolecule.
71225	cellular response to muramyl dipeptide	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a muramyl dipeptide stimulus. Muramyl dipeptide is derived from peptidoglycan.
71226	cellular response to molecule of fungal origin	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by molecules of fungal origin such as chito-octamer oligosaccharide.
71227	cellular response to molecule of oomycetes origin	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by molecules of oomycetes origin.
71228	cellular response to tumor cell	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a tumor cell.
71229	cellular response to acid chemical	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus by the chemical structure of the anion portion of the dissociated acid (rather than the acid acting as a proton donor). The acid chemical may be in gaseous, liquid or solid form.
71230	cellular response to amino acid stimulus	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amino acid stimulus. An amino acid is a carboxylic acids containing one or more amino groups.
71231	cellular response to folic acid	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a folic acid stimulus.
71232	cellular response to histidine	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a histidine stimulus.
71233	cellular response to leucine	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a leucine stimulus.
71234	cellular response to phenylalanine	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a phenylalanine stimulus.
71235	cellular response to proline	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a proline stimulus.
71236	cellular response to antibiotic	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antibiotic stimulus. An antibiotic is a chemical substance produced by a microorganism which has the capacity to inhibit the growth of or to kill other microorganisms.
71237	cellular response to bacteriocin	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bacteriocin stimulus. A bacteriocin is a protein substance released by certain bacteria that kills but does not lyse closely related strains of bacteria. Specific bacteriocins attach to specific receptors on cell walls and induce specific metabolic block, e.g. cessation of nucleic acid or protein synthesis of oxidative phosphorylation.
71238	cellular response to brefeldin A	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a brefeldin A stimulus.
71239	cellular response to streptomycin	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a streptomycin stimulus. Streptomycin is a commonly used antibiotic in cell culture media which acts only on prokaryotes and blocks transition from initiation complex to chain elongating ribosome.
71240	cellular response to food	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a food stimulus; food is anything which, when taken into the body, serves to nourish or build up the tissues or to supply body heat.
71241	cellular response to inorganic substance	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an inorganic substance stimulus.
71242	cellular response to ammonium ion	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ammonium ion stimulus.
71243	cellular response to arsenic-containing substance	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an arsenic stimulus from compounds containing arsenic, including arsenates, arsenites, and arsenides.
71244	cellular response to carbon dioxide	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbon dioxide (CO2) stimulus.
71245	cellular response to carbon monoxide	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbon monoxide (CO) stimulus.
71246	cellular response to chlorate	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chlorate stimulus.
71247	cellular response to chromate	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chromate stimulus.
71248	cellular response to metal ion	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a metal ion stimulus.
71249	cellular response to nitrate	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrate stimulus.
71250	cellular response to nitrite	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrite stimulus.
71251	cellular response to silicon dioxide	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a silicon dioxide stimulus.
71252	cellular response to sulfur dioxide	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sulfur dioxide (SO2) stimulus.
71253	connexin binding	F	Interacting selectively and non-covalently with a connexin, any of a group of related proteins that assemble to form gap junctions.
71254	cytoplasmic U snRNP body	C	A ribonucleoprotein complex that can be visualized as a focus in the cytoplasm, and contains uridine-rich small nuclear ribonucleoproteins (U snRNPs) and essential snRNP assembly factors. These U bodies are invariably found in association with P bodies.
71255	CVT vesicle assembly	P	A vesicle organization process that takes place as part of the CVT pathway, and results in the formation of a double membrane-bounded cytosolic structure that sequesters precursor aminopeptidase I (prAPI).
71256	translocon complex	C	A protein complex that constitutes a specific site of protein translocation across the endoplasmic reticulum, which involves the signal recognition particle receptor. The complex contains a core heterotrimer of alpha, beta and gamma subunits, and may contain additional proteins.
71257	cellular response to electrical stimulus	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electrical stimulus.
71258	cellular response to gravity	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gravitational stimulus.
71259	cellular response to magnetism	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a magnetic stimulus.
71260	cellular response to mechanical stimulus	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mechanical stimulus.
71261	Ssh1 translocon complex	C	A translocon complex that contains a core heterotrimer of alpha, beta and gamma subunits, and may contain additional proteins (translocon-associated proteins or TRAPs); in budding yeast the core proteins are Ssh1p, Sbh2p, and Sss1p. The Ssh1 translocon complex is involved in the cotranslational pathway of protein transport across the ER membrane, and recognizes proteins bearing strongly hydrophobic signal sequences.
71262	regulation of translational initiation in response to starvation	P	Any process that modulates the frequency, rate or extent of translation initiation, as a result of deprivation of nourishment.
71263	negative regulation of translational initiation in response to starvation	P	Any process that stops, prevents or reduces the rate of translation initiation, as a result of deprivation of nourishment.
71264	positive regulation of translational initiation in response to starvation	P	Any process that activates or increases the frequency, rate or extent of translation initiation, as a result of deprivation of nourishment.
71265	L-methionine biosynthetic process	P	The chemical reactions and pathways resulting in the formation of L-methionine, the L-enantiomer of (2S)-2-amino-4-(methylsulfanyl)butanoic acid.
71266	'de novo' L-methionine biosynthetic process	P	The chemical reactions and pathways resulting in the formation of L-methionine, the L-enantiomer of (2S)-2-amino-4-(methylsulfanyl)butanoic acid, from simpler components.
71267	L-methionine salvage	P	Any process that generates L-methionine from derivatives of it, without de novo synthesis.
71268	homocysteine biosynthetic process	P	The chemical reactions and pathways resulting in the formation of homocysteine, 2-amino-4-sulfanylbutanoic acid.
71269	L-homocysteine biosynthetic process	P	The chemical reactions and pathways resulting in the formation of L-homocysteine, the L-enantiomer of 2-amino-4-sulfanylbutanoic acid.
71270	1-butanol metabolic process	P	The chemical reactions and pathways involving 1-butanol, an alkyl primary alcohol with the formula C4H10O.
71271	1-butanol biosynthetic process	P	The chemical reactions and pathways resulting in the formation of 1-butanol, an alkyl primary alcohol with the formula C4H10O.
71272	morphine metabolic process	P	The chemical reactions and pathways involving morphine, 17-methyl-7,8-didehydro-4,5alpha-epoxymorphinan-3,6alpha-diol. Morphine is a highly potent opiate analgesic psychoactive drug obtained form the opium poppy, Papaver somniferum.
71273	morphine catabolic process	P	The chemical reactions and pathways resulting in the breakdown of morphine, 17-methyl-7,8-didehydro-4,5alpha-epoxymorphinan-3,6alpha-diol. Morphine is a highly potent opiate analgesic psychoactive drug obtained form the opium poppy, Papaver somniferum.
71274	isoquinoline alkaloid catabolic process	P	The chemical reactions and pathways resulting in the breakdown of isoquinoline alkaloids, alkaloid compounds that contain bicyclic N-containing aromatic rings and are derived from a 3,4-dihydroxytyramine (dopamine) precursor that undergoes a Schiff base addition with aldehydes of different origin.
71275	cellular response to aluminum ion	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an aluminum ion stimulus.
71276	cellular response to cadmium ion	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cadmium (Cd) ion stimulus.
71277	cellular response to calcium ion	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a calcium ion stimulus.
71278	cellular response to cesium ion	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cesium stimulus.
71279	cellular response to cobalt ion	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cobalt ion stimulus.
71280	cellular response to copper ion	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a copper ion stimulus.
71281	cellular response to iron ion	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iron ion stimulus.
71282	cellular response to iron(II) ion	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iron(II) ion stimulus.
71283	cellular response to iron(III) ion	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iron(III) ion stimulus.
71284	cellular response to lead ion	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lead ion stimulus.
71285	cellular response to lithium ion	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lithium (Li+) ion stimulus.
71286	cellular response to magnesium ion	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a magnesium ion stimulus.
71287	cellular response to manganese ion	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a manganese ion stimulus.
71288	cellular response to mercury ion	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mercury ion stimulus.
71289	cellular response to nickel ion	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nickel ion stimulus.
71290	cellular response to platinum ion	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a platinum stimulus.
71291	cellular response to selenium ion	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from selenium ion.
71292	cellular response to silver ion	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a silver ion stimulus.
71293	cellular response to tellurium ion	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tellurium ion stimulus.
71294	cellular response to zinc ion	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a zinc ion stimulus.
71295	cellular response to vitamin	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin stimulus.
71296	cellular response to biotin	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a biotin stimulus.
71297	cellular response to cobalamin	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cobalamin (vitamin B12) stimulus.
71298	cellular response to L-ascorbic acid	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an L-ascorbic acid (vitamin C) stimulus.
71299	cellular response to vitamin A	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin A stimulus.
71300	cellular response to retinoic acid	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a retinoic acid stimulus.
71301	cellular response to vitamin B1	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin B1 stimulus.
71302	cellular response to vitamin B2	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin B2 stimulus.
71303	cellular response to vitamin B3	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin B3 stimulus.
71304	cellular response to vitamin B6	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin B6 stimulus. Vitamin B6 encompasses pyridoxal, pyridoxamine and pyridoxine and the active form, pyridoxal phosphate.
71305	cellular response to vitamin D	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin D stimulus.
71306	cellular response to vitamin E	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin E stimulus.
71307	cellular response to vitamin K	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vitamin K stimulus.
71308	cellular response to menaquinone	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a menaquinone (vitamin K2) stimulus.
71309	cellular response to phylloquinone	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a phylloquinone (vitamin K1) stimulus.
71310	cellular response to organic substance	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic substance stimulus.
71311	cellular response to acetate	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acetate stimulus.
71312	cellular response to alkaloid	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alkaloid stimulus. Alkaloids are a large group of nitrogenous substances found in naturally in plants, many of which have extracts that are pharmacologically active.
71313	cellular response to caffeine	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a caffeine stimulus. Caffeine is an alkaloid found in numerous plant species, where it acts as a natural pesticide that paralyzes and kills certain insects feeding upon them.
71314	cellular response to cocaine	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cocaine stimulus. Cocaine is a crystalline alkaloid obtained from the leaves of the coca plant.
71315	cellular response to morphine	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a morphine stimulus. Morphine is an opioid alkaloid, isolated from opium, with a complex ring structure.
71316	cellular response to nicotine	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nicotine stimulus.
71317	cellular response to isoquinoline alkaloid	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an isoquinoline alkaloid stimulus. An isoquinoline alkaloid is any member of a group of compounds with the heterocyclic ring structure of benzo(c)pyridine which is a structure characteristic of the group of opium alkaloids.
71318	cellular response to ATP	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ATP (adenosine 5'-triphosphate) stimulus.
71319	cellular response to benzoic acid	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a benzoic acid stimulus.
71320	cellular response to cAMP	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cAMP (cyclic AMP, adenosine 3',5'-cyclophosphate) stimulus.
71321	cellular response to cGMP	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cGMP (cyclic GMP, guanosine 3',5'-cyclophosphate) stimulus.
71322	cellular response to carbohydrate stimulus	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbohydrate stimulus.
71323	cellular response to chitin	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chitin stimulus.
71324	cellular response to disaccharide stimulus	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disaccharide stimulus.
71325	cellular response to mannitol stimulus	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mannitol stimulus.
71326	cellular response to monosaccharide stimulus	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a monosaccharide stimulus.
71327	cellular response to trehalose stimulus	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a trehalose stimulus.
71328	cellular response to maltose stimulus	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a maltose stimulus.
71329	cellular response to sucrose stimulus	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sucrose stimulus.
71330	cellular response to trehalose-6-phosphate stimulus	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a trehalose-6-phosphate stimulus.
71331	cellular response to hexose stimulus	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hexose stimulus.
71332	cellular response to fructose stimulus	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fructose stimulus.
71333	cellular response to glucose stimulus	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucose stimulus.
71334	cellular response to rhamnose stimulus	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a rhamnose stimulus.
71335	hair follicle cell proliferation	P	The multiplication or reproduction of hair follicle cells, resulting in the expansion of a cell population.
71336	regulation of hair follicle cell proliferation	P	Any process that modulates the frequency, rate or extent of hair follicle cell proliferation.
71337	negative regulation of hair follicle cell proliferation	P	Any process that stops, prevents or reduces the rate or extent of hair follicle cell proliferation.
71338	positive regulation of hair follicle cell proliferation	P	Any process that activates or increases the rate or extent of hair follicle cell proliferation.
71339	MLL1 complex	C	A protein complex that can methylate lysine-4 of histone H3. MLL1/MLL is the catalytic methyltransferase subunit, and the complex also contains the core components ASH2L, HCFC1/HCF1 WDR5 and RBBP5.
71340	skeletal muscle acetylcholine-gated channel clustering	P	The accumulation of acetylcholine-gated cation channels in a narrow, central region of muscle fibers, in apposition to nerve terminals.
71341	medial cortical node	C	A component of the cell division site that contains the mid1, cdr2, wee1, klp8, and blt1 proteins, and is involved in contractile ring localization. Medial cortical node complexes appear as cortical dots in the middle of the cell during interphase, and function to recruit other ring components in early mitosis.
71342	regulation of establishment of actomyosin contractile ring localization	P	Any process that modulates the frequency, rate or extent of the process in which a contractile ring is assembled in a specific location that contributes to cytokinesis during cell cycle.
71344	diphosphate metabolic process	P	The chemical reactions and pathways involving diphosphate, the anion or salt of diphosphoric acid.
71345	cellular response to cytokine stimulus	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytokine stimulus.
71346	cellular response to interferon-gamma	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interferon-gamma stimulus. Interferon gamma is the only member of the type II interferon found so far.
71347	cellular response to interleukin-1	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-1 stimulus.
71348	cellular response to interleukin-11	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-11 stimulus.
71349	cellular response to interleukin-12	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-12 stimulus.
71350	cellular response to interleukin-15	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-15 stimulus.
71351	cellular response to interleukin-18	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-18 stimulus.
71352	cellular response to interleukin-2	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-2 stimulus.
71353	cellular response to interleukin-4	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-4 stimulus.
71354	cellular response to interleukin-6	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-6 stimulus.
71355	cellular response to interleukin-9	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-9 stimulus.
71356	cellular response to tumor necrosis factor	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tumor necrosis factor stimulus.
71357	cellular response to type I interferon	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a type I interferon stimulus. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families.
71358	cellular response to type III interferon	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a type III interferon stimulus. Interferon lambda is the only member of the type III interferon found so far.
71359	cellular response to dsRNA	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a double-stranded RNA stimulus.
71360	cellular response to exogenous dsRNA	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an exogenous double-stranded RNA stimulus.
71361	cellular response to ethanol	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ethanol stimulus.
71362	cellular response to ether	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ether stimulus.
71363	cellular response to growth factor stimulus	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a growth factor stimulus.
71364	cellular response to epidermal growth factor stimulus	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an epidermal growth factor stimulus.
71365	cellular response to auxin stimulus	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an auxin stimulus.
71366	cellular response to indolebutyric acid stimulus	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an indolebutyric acid stimulus.
71367	cellular response to brassinosteroid stimulus	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a brassinosteroid stimulus.
71368	cellular response to cytokinin stimulus	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytokinin stimulus.
71369	cellular response to ethylene stimulus	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ethylene (ethene) stimulus.
71370	cellular response to gibberellin stimulus	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gibberellin stimulus.
71371	cellular response to gonadotropin stimulus	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gonadotropin stimulus.
71372	cellular response to follicle-stimulating hormone stimulus	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a follicle-stimulating hormone stimulus.
71373	cellular response to luteinizing hormone stimulus	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a luteinizing hormone stimulus.
71374	cellular response to parathyroid hormone stimulus	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a parathyroid hormone stimulus.
71375	cellular response to peptide hormone stimulus	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptide hormone stimulus. A peptide hormone is any of a class of peptides that are secreted into the blood stream and have endocrine functions in living animals.
71376	cellular response to corticotropin-releasing hormone stimulus	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a corticotropin-releasing hormone stimulus. Corticotropin-releasing hormone is a peptide hormone involved in the stress response.
71377	cellular response to glucagon stimulus	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucagon stimulus.
71378	cellular response to growth hormone stimulus	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a growth hormone stimulus. Growth hormone is a peptide hormone that binds to the growth hormone receptor and stimulates growth.
71379	cellular response to prostaglandin stimulus	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin stimulus.
71380	cellular response to prostaglandin E stimulus	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin E stimulus.
71381	cellular response to prostaglandin F stimulus	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin F stimulus.
71382	cellular response to prostaglandin I stimulus	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin I stimulus.
71383	cellular response to steroid hormone stimulus	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a steroid hormone stimulus.
71384	cellular response to corticosteroid stimulus	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a corticosteroid hormone stimulus. A corticosteroid is a steroid hormone that is produced in the adrenal cortex. Corticosteroids are involved in a wide range of physiologic systems such as stress response, immune response and regulation of inflammation, carbohydrate metabolism, protein catabolism, blood electrolyte levels, and behavior. They include glucocorticoids and mineralocorticoids.
71385	cellular response to glucocorticoid stimulus	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucocorticoid stimulus. Glucocorticoids are hormonal C21 corticosteroids synthesized from cholesterol with the ability to bind with the cortisol receptor and trigger similar effects. Glucocorticoids act primarily on carbohydrate and protein metabolism, and have anti-inflammatory effects.
71386	cellular response to corticosterone stimulus	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a corticosterone stimulus. Corticosterone is a 21 carbon steroid hormone of the corticosteroid type, produced in the cortex of the adrenal glands. In many species, corticosterone is the principal glucocorticoid, involved in regulation of fuel metabolism, immune reactions, and stress responses.
71387	cellular response to cortisol stimulus	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cortisol stimulus. Cortisol is the major natural glucocorticoid synthesized in the zona fasciculata of the adrenal cortex; it affects the metabolism of glucose, protein, and fats and has appreciable mineralocorticoid activity. It also regulates the immune system and affects many other functions.
71388	cellular response to cortisone stimulus	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cortisone stimulus. Cortisone is a natural glucocorticoid steroid hormone that is metabolically convertible to cortisol. Cortisone is synthesized from cholesterol in the cortex of the adrenal gland under the stimulation of adrenocorticotropin hormone (ACTH). The main physiological effect of cortisone is on carbohydrate metabolism; it can stimulate increased glucose release from the liver, increased liver glycogen synthesis, and decreased utilization of glucose by the tissues.
71389	cellular response to mineralocorticoid stimulus	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mineralocorticoid stimulus. Mineralocorticoids are hormonal C21 corticosteroids synthesized from cholesterol and characterized by their similarity to aldosterone. Mineralocorticoids act primarily on water and electrolyte balance.
71390	cellular response to ecdysone	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ecdysone stimulus.
71391	cellular response to estrogen stimulus	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stimulus by an estrogen, C18 steroid hormones that can stimulate the development of female sexual characteristics.
71392	cellular response to estradiol stimulus	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stimulus by estradiol, a C18 steroid hormone hydroxylated at C3 and C17 that acts as a potent estrogen.
71393	cellular response to progesterone stimulus	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a progesterone stimulus.
71394	cellular response to testosterone stimulus	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a testosterone stimulus.
71395	cellular response to jasmonic acid stimulus	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a jasmonic acid stimulus.
71396	cellular response to lipid	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipid stimulus.
71397	cellular response to cholesterol	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cholesterol stimulus.
71398	cellular response to fatty acid	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fatty acid stimulus.
71399	cellular response to linoleic acid	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a linoleic acid stimulus.
71400	cellular response to oleic acid	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oleic acid stimulus.
71401	cellular response to triglyceride	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a triglyceride stimulus.
71402	cellular response to lipoprotein particle stimulus	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipoprotein particle stimulus.
71403	cellular response to high density lipoprotein particle stimulus	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a high density lipoprotein particle stimulus.
71404	cellular response to low-density lipoprotein particle stimulus	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a low-density lipoprotein particle stimulus.
71405	cellular response to methanol	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methanol stimulus.
71406	cellular response to methylmercury	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methylmercury stimulus.
71407	cellular response to organic cyclic compound	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic cyclic compound stimulus.
71408	cellular response to cycloalkane	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cycloalkane stimulus. A cycloalkane is a cyclic saturated hydrocarbon having the general formula CnH2n.
71409	cellular response to cycloheximide	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cycloheximide stimulus. Cycloheximide (actidione) is an antibiotic produced by some Streptomyces species which interferes with protein synthesis in eukaryotes.
71410	cellular response to cyclopentenone	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cyclopentenone stimulus. Cyclopentenones are oxylipins derived from polyunsaturated fatty acids. They are structurally similar to jasmonic acid, but contain a reactive unsaturated carbonyl structure in the cyclo-ring. Cyclopentenones include phytoprostanes and 12-oxo-phytodienoic acid.
71411	cellular response to fluoxetine	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fluoxetine stimulus. Fluoxetine increases the extracellular level of the neurotransmitter serotonin by inhibiting its reuptake into the presynaptic cell, increasing the level of serotonin available to bind to the postsynaptic receptor.
71412	cellular response to genistein	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a genistein stimulus.
71413	cellular response to hydroxyisoflavone	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydroxyisoflavone stimulus.
71414	cellular response to methotrexate	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methotrexate stimulus. Methotrexate is 4-amino-10-methylformic acid, a folic acid analogue that is a potent competitive inhibitor of dihydrofolate reductase.
71415	cellular response to purine-containing compound	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a purine-containing compound stimulus.
71416	cellular response to tropane	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tropane stimulus. Tropane is a nitrogenous bicyclic organic compound mainly known for a group of alkaloids derived from it (called tropane alkaloids), which include, among others, atropine and cocaine.
71417	cellular response to organonitrogen compound	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organonitrogen stimulus. An organonitrogen compound is formally a compound containing at least one carbon-nitrogen bond.
71418	cellular response to amine stimulus	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amine stimulus. An amine is a compound formally derived from ammonia by replacing one, two or three hydrogen atoms by hydrocarbyl groups.
71419	cellular response to amphetamine	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amphetamine stimulus. Amphetamines consist of a group of compounds related to alpha-methylphenethylamine.
71420	cellular response to histamine	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a histamine stimulus. Histamine, the biogenic amine 2-(1H-imidazol-4-yl)ethanamine, is involved in local immune responses as well as regulating physiological function in the gut and acting as a neurotransmitter.
71421	manganese ion transmembrane transport	P	A process in which a manganese ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.
71422	succinate transmembrane transport	P	A process in which a succinate ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.
71423	malate transmembrane transport	P	A process in which a malate ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.
71424	rRNA (cytosine-N4-)-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + rRNA = S-adenosyl-L-homocysteine + rRNA containing N4-methylcytosine.
71425	hematopoietic stem cell proliferation	P	The expansion of a hematopoietic stem cell population by cell division. A hematopoietic stem cell is a stem cell from which all cells of the lymphoid and myeloid lineages develop.
71426	ribonucleoprotein complex export from nucleus	P	The directed movement of a ribonucleoprotein complex from the nucleus to the cytoplasm.
71427	mRNA-containing ribonucleoprotein complex export from nucleus	P	The directed movement of a ribonucleoprotein complex that contains messenger RNA from the nucleus to the cytoplasm.
71428	rRNA-containing ribonucleoprotein complex export from nucleus	P	The directed movement of a ribonucleoprotein complex that contains ribosomal RNA from the nucleus to the cytoplasm.
71429	snRNA-containing ribonucleoprotein complex export from nucleus	P	The directed movement of a ribonucleoprotein complex that contains small nuclear RNA from the nucleus to the cytoplasm.
71430	pre-miRNA-containing ribonucleoprotein complex export from nucleus	P	The directed movement of a ribonucleoprotein complex that contains pre-microRNA from the nucleus to the cytoplasm.
71431	tRNA-containing ribonucleoprotein complex export from nucleus	P	The directed movement of a ribonucleoprotein complex that contains transfer RNA from the nucleus to the cytoplasm.
71432	peptide mating pheromone maturation involved in conjugation with cellular fusion	P	The formation of a mature peptide mating pheromone by proteolysis and/or modification of a peptide precursor, occurring in the context of conjugation with cellular fusion.
71433	cell wall repair	P	A process of cell wall organization that results in the restoration of the cell wall following damage.
71434	cell chemotaxis to angiotensin	P	The directed movement of a motile cell in response to the presence of angiotensin.
71435	potassium ion export	P	The directed movement of potassium ions out of a cell or organelle.
71436	sodium ion export	P	The directed movement of sodium ions out of a cell or organelle.
71437	invadopodium	C	A cell projection that emerges from the ECM-facing surface of a cell, is enriched in actin and associated cytoskeletal proteins, and displays localized proteolytic activity toward the substrate.
71438	invadopodium membrane	C	The portion of the plasma membrane surrounding an invadopodium.
71439	clathrin complex	C	A protein complex that consists of three clathrin heavy chains and three clathrin light chains, organized into a symmetrical three-legged structure called a triskelion. In clathrin-coated vesicles clathrin is the main component of the coat and forms a polymeric mechanical scaffold on the vesicle surface.
71440	regulation of histone H3-K14 acetylation	P	Any process that modulates the frequency, rate or extent of the addition of an acetyl group to histone H3 at position 14 of the histone.
71441	negative regulation of histone H3-K14 acetylation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the addition of an acetyl group to histone H3 at position 14 of the histone.
71442	positive regulation of histone H3-K14 acetylation	P	Any process that activates or increases the frequency, rate or extent of the addition of an acetyl group to histone H3 at position 14 of the histone.
71443	tDNA binding	F	Interacting selectively and non-covalently with DNA sequences encoding transfer RNA.
71444	cellular response to pheromone	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pheromone stimulus.
71446	cellular response to salicylic acid stimulus	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a salicylic acid stimulus.
71447	cellular response to hydroperoxide	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydroperoxide stimulus. Hydroperoxides are monosubstitution products of hydrogen peroxide, HOOH.
71448	cellular response to alkyl hydroperoxide	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alkyl hydroperoxide stimulus. Alkyl hydroperoxides are monosubstitution products of hydrogen peroxide, HOOH, where the substituent is an alkyl group.
71449	cellular response to lipid hydroperoxide	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipid hydroperoxide stimulus. Lipid hydroperoxide is the highly reactive primary oxygenated products of polyunsaturated fatty acids.
71450	cellular response to oxygen radical	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oxygen radical stimulus. An oxygen radical is any oxygen species that carries a free electron; examples include hydroxyl radicals and the superoxide anion.
71451	cellular response to superoxide	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a superoxide stimulus. Superoxide is the anion, oxygen-, formed by addition of one electron to dioxygen (O2) or any compound containing the superoxide anion.
71452	cellular response to singlet oxygen	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a singlet oxygen stimulus. Singlet oxygen is a dioxygen (O2) molecule in which two 2p electrons have similar spin. Singlet oxygen is more highly reactive than the form in which these electrons are of opposite spin, and it is produced in mutant chloroplasts lacking carotenoids and by leukocytes during metabolic burst.
71453	cellular response to oxygen levels	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of oxygen.
71454	cellular response to anoxia	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating a decline in oxygen levels to trace amounts, <0.1%.
71455	cellular response to hyperoxia	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating increased oxygen tension.
71456	cellular response to hypoxia	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level.
71457	cellular response to ozone	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ozone stimulus.
71458	integral component of cytoplasmic side of endoplasmic reticulum membrane	C	The component of the endoplasmic reticulum membrane consisting of the gene products that penetrate only the cytoplasmic side of the membrane.
71459	protein localization to chromosome, centromeric region	P	Any process in which a protein is transported to, or maintained at, the centromeric region of a chromosome.
71460	cellular response to cell-matrix adhesion	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of cell-matrix adhesion.
71461	cellular response to redox state	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating redox state. Redox state refers to the balance of oxidized versus reduced forms of electron donors and acceptors in an organelle, cell or organ; plastoquinone, glutathione (GSH/GSSG), and nicotinamide nucleotides (NAD+/NADH and NADP+/NADPH) are among the most important.
71462	cellular response to water stimulus	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of water.
71463	cellular response to humidity	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a humidity stimulus, moisture in the atmosphere.
71464	cellular response to hydrostatic pressure	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrostatic pressure stimulus. Hydrostatic pressure is the force acting on an object in a system where the fluid is at rest (as opposed to moving). The weight of the fluid above the object creates pressure on it.
71465	cellular response to desiccation	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a desiccation stimulus, extreme dryness resulting from the prolonged deprivation of water.
71466	cellular response to xenobiotic stimulus	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a xenobiotic compound stimulus. Xenobiotic compounds are compounds foreign to living organisms.
71467	cellular response to pH	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus. pH is a measure of the acidity or basicity of an aqueous solution.
71468	cellular response to acidic pH	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus with pH < 7. pH is a measure of the acidity or basicity of an aqueous solution.
71469	cellular response to alkaline pH	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus with pH > 7. pH is a measure of the acidity or basicity of an aqueous solution.
71470	cellular response to osmotic stress	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell.
71471	cellular response to non-ionic osmotic stress	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of non-ionic solutes (e.g. mannitol, sorbitol) in the environment.
71472	cellular response to salt stress	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment.
71473	cellular response to cation stress	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of cation stress, an increase or decrease in the concentration of positively charged ions in the environment.
71474	cellular hyperosmotic response	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a hyperosmotic environment, i.e. an environment with a higher concentration of solutes than the organism or cell.
71475	cellular hyperosmotic salinity response	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, an increase in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment.
71476	cellular hypotonic response	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a hypotonic environment, i.e. an environment with a lower concentration of solutes than the organism or cell.
71477	cellular hypotonic salinity response	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment.
71478	cellular response to radiation	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electromagnetic radiation stimulus. Electromagnetic radiation is a propagating wave in space with electric and magnetic components. These components oscillate at right angles to each other and to the direction of propagation.
71479	cellular response to ionizing radiation	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ionizing radiation stimulus. Ionizing radiation is radiation with sufficient energy to remove electrons from atoms and may arise from spontaneous decay of unstable isotopes, resulting in alpha and beta particles and gamma rays. Ionizing radiation also includes X-rays.
71480	cellular response to gamma radiation	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gamma radiation stimulus. Gamma radiation is a form of electromagnetic radiation (EMR) or light emission of a specific frequency produced from sub-atomic particle interaction, such as electron-positron annihilation and radioactive decay. Gamma rays are generally characterized as EMR having the highest frequency and energy, and also the shortest wavelength, within the electromagnetic radiation spectrum.
71481	cellular response to X-ray	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of X-ray radiation. An X-ray is a form of electromagnetic radiation with a wavelength in the range of 10 nanometers to 100 picometers (corresponding to frequencies in the range 30 PHz to 3 EHz).
71482	cellular response to light stimulus	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a light stimulus, electromagnetic radiation of wavelengths classified as infrared, visible or ultraviolet light.
71483	cellular response to blue light	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a blue light stimulus. Blue light is electromagnetic radiation with a wavelength of between 440 and 500nm.
71484	cellular response to light intensity	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a light intensity stimulus.
71485	cellular response to absence of light	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an absence of light stimuli.
71486	cellular response to high light intensity	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a high light intensity stimulus.
71487	cellular response to low light intensity stimulus	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a low light intensity stimulus. Low light intensity is defined as a level of electromagnetic radiation at or below 0.1 micromols/m2.
71488	cellular response to very low light intensity stimulus	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a very low light intensity stimulus. A very low light intensity stimulus is defined as a level of electromagnetic radiation below 0.001 mmol/m2/sec.
71489	cellular response to red or far red light	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a red or far red light stimulus. Red light is electromagnetic radiation of wavelength of 580-700nm. Far red light is electromagnetic radiation of wavelength 700-800nm. An example of this response is seen at the beginning of many plant species developmental stages. These include germination, and the point when cotyledon expansion is triggered. In certain species these processes take place in response to absorption of red light by the pigment molecule phytochrome, but the signal can be reversed by exposure to far red light. During the initial phase the phytochrome molecule is only present in the red light absorbing form, but on absorption of red light it changes to a far red light absorbing form, triggering progress through development. An immediate short period of exposure to far red light entirely returns the pigment to its initial state and prevents triggering of the developmental process. A thirty minute break between red and subsequent far red light exposure renders the red light effect irreversible, and development then occurs regardless of whether far red light exposure subsequently occurs.
71490	cellular response to far red light	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of far red light stimulus. Far red light is electromagnetic radiation of wavelength 700-800nm. An example of this response is seen at the beginning of many plant species developmental stages. These include germination, and the point when cotyledon expansion is triggered. In certain species these processes take place in response to absorption of red light by the pigment molecule phytochrome, but the signal can be reversed by exposure to far red light. During the initial phase the phytochrome molecule is only present in the red light absorbing form, but on absorption of red light it changes to a far red light absorbing form, triggering progress through development. An immediate short period of exposure to far red light entirely returns the pigment to its initial state and prevents triggering of the developmental process. A thirty minute break between red and subsequent far red light exposure renders the red light effect irreversible, and development then occurs regardless of whether far red light exposure subsequently occurs.
71491	cellular response to red light	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a red light stimulus. Red light is electromagnetic radiation of wavelength of 580-700nm. An example of this response is seen at the beginning of many plant species developmental stages. These include germination, and the point when cotyledon expansion is triggered. In certain species these processes take place in response to absorption of red light by the pigment molecule phytochrome, but the signal can be reversed by exposure to far red light. During the initial phase the phytochrome molecule is only present in the red light absorbing form, but on absorption of red light it changes to a far red light absorbing form, triggering progress through development. An immediate short period of exposure to far red light entirely returns the pigment to its initial state and prevents triggering of the developmental process. A thirty minute break between red and subsequent far red light exposure renders the red light effect irreversible, and development then occurs regardless of whether far red light exposure subsequently occurs.
71492	cellular response to UV-A	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a UV-A radiation stimulus. UV-A radiation (UV-A light) spans the wavelengths 315 to 400 nm.
71493	cellular response to UV-B	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a UV-B radiation stimulus. UV-B radiation (UV-B light) spans the wavelengths 280 to 315 nm.
71494	cellular response to UV-C	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a UV-C radiation stimulus. UV-C radiation (UV-C light) spans the wavelengths 100 to 280 nm.
71495	cellular response to endogenous stimulus	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus arising within the organism.
71496	cellular response to external stimulus	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an external stimulus.
71497	cellular response to freezing	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a freezing stimulus, temperatures below 0 degrees Celsius.
71498	cellular response to fluid shear stress	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fluid shear stress stimulus. Fluid shear stress is the force acting on an object in a system where the fluid is moving across a solid surface.
71499	cellular response to laminar fluid shear stress	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a laminar fluid shear stress stimulus. Laminar fluid flow is the force acting on an object in a system where the fluid is moving across a solid surface in parallel layers.
71500	cellular response to nitrosative stress	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrosative stress stimulus. Nitrosative stress is a state often resulting from exposure to high levels of nitric oxide (NO) or the highly reactive oxidant peroxynitrite, which is produced following interaction of NO with superoxide anions.
71501	cellular response to sterol depletion	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating deprivation of sterols. Sterols are a group of steroids characterized by the presence of one or more hydroxyl groups and a hydrocarbon side-chain in the molecule.
71502	cellular response to temperature stimulus	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a temperature stimulus.
71503	response to heparin	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heparin stimulus.
71504	cellular response to heparin	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heparin stimulus.
71505	response to mycophenolic acid	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mycophenolic acid stimulus.
71506	cellular response to mycophenolic acid	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mycophenolic acid stimulus.
71507	MAPK cascade involved in conjugation with cellular fusion	P	A MAPK cascade that contributes to conjugation with cellular fusion.
71508	activation of MAPK activity involved in conjugation with cellular fusion	P	Any process that initiates the activity of the inactive enzyme MAP kinase in the context of conjugation with cellular fusion.
71509	activation of MAPKK activity involved in conjugation with cellular fusion	P	Any process that initiates the activity of the inactive enzyme MAP kinase kinase in the context of conjugation with cellular fusion.
71510	activation of MAPKKK activity involved in conjugation with cellular fusion	P	Any process that initiates the activity of the inactive enzyme MAP kinase kinase kinase in the context of conjugation with cellular fusion.
71511	inactivation of MAPK activity involved in conjugation with cellular fusion	P	Any process that terminates the activity of the active enzyme MAP kinase in the context of conjugation with cellular fusion.
71512	MAPK import into nucleus involved in conjugation with cellular fusion	P	The directed movement of a MAP kinase to the nucleus that occurs in the context of conjugation with cellular fusion.
71513	phosphopantothenoylcysteine decarboxylase complex	C	A protein complex that catalyzes decarboxylation of 4'-phosphopantothenoylcysteine to yield 4'-phosphopantetheine; this is the third step in the biosynthesis of Coenzyme A. The complex is homotrimeric in many eukaryotes, but is a heterotrimer in Saccharomyces.
71514	genetic imprinting	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving macromolecules by a mechanism that is mediated by DNA, is mitotically or meiotically heritable, or is stably self-propagated in the cytoplasm of a resting cell, and does not entail a change in DNA sequence.
71515	genetic imprinting at mating-type locus	P	A genetic imprinting process in which a stable single-strand DNA lesion triggers programmed gene conversion at the mating-type locus, thereby restricting mating-type interconversion to one of the two sister chromatids during DNA replication.
71516	establishment of imprinting at mating-type locus	P	The initial formation of a stable single-strand DNA lesion that triggers programmed gene conversion at the mating-type locus, thereby restricting mating-type interconversion to one of the two sister chromatids during DNA replication.
71517	maintenance of imprinting at mating-type locus	P	Any process involved in preserving the structure of a stable single-strand DNA lesion that triggers programmed gene conversion at the mating-type locus, thereby restricting mating-type interconversion to one of the two sister chromatids during DNA replication.
71518	autoinducer-2 kinase activity	F	Catalysis of the reaction: 4,5-dihydroxy-pentane-2,3-dione + ATP = 5-phospho-4-hydroxy-pentane-2,3-dione (P-DPD) + ADP.
71519	actomyosin contractile ring actin filament bundle assembly	P	A process of actin filament bundle formation that occurs in the context of assembling an actomyosin contractile ring during cytokinesis.
71520	actomyosin contractile ring assembly actin filament bundle convergence	P	A process of actin filament bundle distribution that occurs in the context of assembling an actomyosin contractile ring during cytokinesis, and that results in the compaction of actin filaments into a tight ring.
71521	Cdc42 GTPase complex	C	A protein complex formed by the association of the small GTPase Cdc42 with additional proteins. In Schizosaccharomyces the complex contains the Cdc42, Ras1, Scd1, Scd2, andShk1 proteins, and functions in the Ras1-Scd GTPase signalling pathway.
71522	ureidoglycine aminohydrolase activity	F	Catalysis of the reaction: ureidoglycine + H2O = S-ureidoglycolate + NH3.
71523	TIR domain-mediated complex assembly	P	A process of protein complex assembly in which the arrangement and bonding together of the set of components that form the protein complex is mediated by a TIR domain interaction.
71524	pyrrolysine biosynthetic process	P	The chemical reactions and pathways resulting in the formation of pyrrolysine, N6-{[(2R,3R)-3-methyl-3,4-dihydro-2H-pyrrol-2-yl]carbonyl}-L-lysine.
71525	pyrrolysine metabolic process	P	The chemical reactions and pathways involving pyrrolysine, N6-{[(2R,3R)-3-methyl-3,4-dihydro-2H-pyrrol-2-yl]carbonyl}-L-lysine.
71526	semaphorin-plexin signaling pathway	P	A series of molecular signals generated as a consequence of a semaphorin receptor (composed of a plexin and a neurophilin) binding to a semaphorin ligand.
71527	semaphorin-plexin signaling pathway involved in outflow tract morphogenesis	P	A series of molecular signals generated as a consequence of a semaphorin receptor (composed of a plexin and a neurophilin) binding to a semaphorin ligand that contributes to outflow tract morphogenesis.
71528	tRNA re-export from nucleus	P	The directed movement from the nucleus to the cytoplasm of a tRNA that was previously exported to the cytoplasm and then imported back into the nucleus. The processes of primary tRNA export and secondary export (re-export) can be distinguished because in organisms in which tRNA splicing occurs in the cytoplasm, the export of a mature tRNA must occur by re-export.
71529	cementum mineralization	P	The process in which calcium salts, mainly carbonated hydroxyapatite, are deposited into the initial acellular cementum.
71530	FHA domain-mediated complex assembly	P	A process of protein complex assembly in which the arrangement and bonding together of the set of components that form the protein complex is mediated by an FHA (forkhead-associated) domain interaction.
71531	Rel homology domain-mediated complex assembly	P	A process of protein complex assembly in which the arrangement and bonding together of the set of components that form the protein complex is mediated by a Rel homology domain (RHD) interaction.
71532	ankyrin repeat binding	F	Interacting selectively and non-covalently with an ankyrin repeat of a protein. Ankyrin repeats are tandemly repeated modules of about 33 amino acids; each repeat folds into a helix-loop-helix structure with a beta-hairpin/loop region projecting out from the helices at a 90-degree angle, and repeats stack to form an L-shaped structure.
71533	ankyrin repeat-mediated complex assembly	P	A process of protein complex assembly in which the arrangement and bonding together of the set of components that form the protein complex is mediated by an ankyrin repeat interaction.
71534	zf-TRAF domain-mediated complex assembly	P	A process of protein complex assembly in which the arrangement and bonding together of the set of components that form the protein complex is mediated by a TRAF-type zinc finger (zf-TRAF) domain interaction.
71535	RING-like zinc finger domain binding	F	Interacting selectively and non-covalently with a RING-like zinc finger domain domain of a protein. The RING-like domain is a zinc finger domain that is related to the C3HC4 RING finger domain.
71536	RING-like zinc finger domain-mediated complex assembly	P	A process of protein complex assembly in which the arrangement and bonding together of the set of components that form the protein complex is mediated by a RING-like zinc finger domain interaction.
71537	C3HC4-type RING finger domain-mediated complex assembly	P	A process of protein complex assembly in which the arrangement and bonding together of the set of components that form the protein complex is mediated by a C3HC4-type RING finger domain interaction.
71538	SH2 domain-mediated complex assembly	P	A process of protein complex assembly in which the arrangement and bonding together of the set of components that form the protein complex is mediated by an SH2 domain interaction.
71539	protein localization to centrosome	P	A process in which a protein is transported to, or maintained at, the centrosome.
71540	eukaryotic translation initiation factor 3 complex, eIF3e	C	An eukaryotic translation initiation factor 3 complex that contains the PCI-domain protein eIF3e.
71541	eukaryotic translation initiation factor 3 complex, eIF3m	C	An eukaryotic translation initiation factor 3 complex that contains the PCI-domain protein eIF3m.
71542	dopaminergic neuron differentiation	P	The process in which a neuroblast acquires the specialized structural and functional features of a dopaminergic neuron, a neuron that secretes dopamine.
71543	diphosphoinositol polyphosphate metabolic process	P	The chemical reactions and pathways involving a diphosphoinositol polyphosphate, 1,2,3,4,5,6-cyclohexanehexol with one or more diphosphate groups and multiple monophosphate groups attached.
71544	diphosphoinositol polyphosphate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of a diphosphoinositol polyphosphate, 1,2,3,4,5,6-cyclohexanehexol with one or more diphosphate groups and multiple monophosphate groups attached.
71545	inositol phosphate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of an inositol phosphate, 1,2,3,4,5,6-cyclohexanehexol, with one or more phosphate groups attached.
71546	pi-body	C	A P granule that contains the PIWIL2-TDRD1 module, a set of proteins that act in the primary piRNA pathway. The pi-body corresponds to the cementing material between mitochondria found in gonocytes.
71547	piP-body	C	A P granule that contains the PIWIL4-TDRD9 module, a set of proteins that act in the secondary piRNA pathway.
71548	response to dexamethasone	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dexamethasone stimulus.
71549	cellular response to dexamethasone stimulus	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dexamethasone stimulus.
71550	death-inducing signaling complex assembly	P	A process of protein complex assembly in which the arrangement and bonding together of the set of components that form the protein complex is mediated by a death domain (DD) interaction, as part of the extrinsic apoptotic signaling pathway.
71551	RIP homotypic interaction motif binding	F	Interacting selectively and non-covalently with a RIP homotypic interaction motif (RHIM) of a protein. The RHIM is a 16-amino-acid motif found in some members, including RIP3, of a family of related kinases.
71552	RIP homotypic interaction motif-mediated complex assembly	P	A process of protein complex assembly in which the arrangement and bonding together of the set of components that form the protein complex is mediated by a RIP homotypic interaction motif (RHIM) interaction.
71553	G-protein coupled pyrimidinergic nucleotide receptor activity	F	Combining with a pyrimidine nucleotide and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.
71554	cell wall organization or biogenesis	P	A process that results in the biosynthesis of constituent macromolecules, assembly, arrangement of constituent parts, or disassembly of a cell wall.
71555	cell wall organization	P	A process that results in the assembly, arrangement of constituent parts, or disassembly of the cell wall, the rigid or semi-rigid envelope lying outside the cell membrane of plant, fungal and most prokaryotic cells, maintaining their shape and protecting them from osmotic lysis.
71556	integral component of lumenal side of endoplasmic reticulum membrane	C	The component of the endoplasmic reticulum membrane consisting of the gene products that penetrate only the lumenal side of the membrane.
71557	histone H3-K27 demethylation	P	The modification of histone H3 by the removal of a methyl group from lysine at position 27 of the histone.
71558	histone demethylase activity (H3-K27 specific)	F	Catalysis of the removal of a methyl group from lysine at position 27 of the histone H3 protein.
71559	response to transforming growth factor beta	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a transforming growth factor beta stimulus.
71560	cellular response to transforming growth factor beta stimulus	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a transforming growth factor beta stimulus.
71561	nucleus-vacuole junction	C	An organelle membrane contact site formed between the vacuole membrane and the outer nuclear membrane. In S. cerevisiae these contacts are mediated through direct physical interaction between Vac8p and Nvj1p.
71562	nucleus-vacuole junction assembly	P	The aggregation, arrangement and bonding together of a set of components to form a nucleus-vacuole junction, which are membrane contact sites formed between the vacuole membrane and the outer nuclear membrane. In S. cerevisiae these contacts are mediated through direct physical interaction between Vac8p and Nvj1p.
71563	Myo2p-Vac17p-Vac8p transport complex	C	A protein complex that is involved in transport of vacuoles to a newly formed daughter cell. In yeast, this complex is composed of Myo2p, Vac17p, and Vac8p.
71564	npBAF complex	C	A SWI/SNF-type complex that is found in neural stem or progenitor cells, and in human contains actin and proteins encoded by the ARID1A/BAF250A or ARID1B/BAF250B, SMARCD1/BAF60A, SMARCD3/BAF60C, SMARCA2/BRM/BAF190B, SMARCA4/BRG1/BAF190A, SMARCB1/BAF47, SMARCC1/BAF155, SMARCE1/BAF57, SMARCC2/BAF170, PHF10/BAF45A, ACTL6A/BAF53A genes. The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells.
71565	nBAF complex	C	A SWI/SNF-type complex that is found in post-mitotic neurons, and in human contains actin and proteins encoded by the ARID1A/BAF250A or ARID1B/BAF250B, SMARCD1/BAF60A, SMARCD3/BAF60C, SMARCA2/BRM/BAF190B, SMARCA4/BRG1/BAF190A, SMARCB1/BAF47, SMARCC1/BAF155, SMARCE1/BAF57, SMARCC2/BAF170, DPF1/BAF45B, DPF3/BAF45C, ACTL6B/BAF53B genes. The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth.
71566	UFM1 activating enzyme activity	F	Catalysis of the activation of the small ubiquitin-related modifier UFM1, through the formation of an ATP-dependent high-energy thiolester bond.
71567	UFM1 hydrolase activity	F	Catalysis of the hydrolysis of UFM1, a small ubiquitin-related modifier, from previously modified substrates.
71568	UFM1 transferase activity	F	Catalysis of the transfer of UFM1 from one protein to another via the reaction X-UFM1 + Y --> Y-UFM1 + X, where both X-UFM1 and Y-UFM1 are covalent linkages.
71569	protein ufmylation	P	Covalent attachment of the ubiquitin-like protein UFM1 to another protein.
71570	cement gland development	P	The process whose specific outcome is the progression of the cement gland over time, from its formation to the mature structure. The cement gland is a simple mucus-secreting organ positioned at the anterior of amphibious embryos. The cement gland attaches the newly hatched embryo to a support before the hatchling can swim well or feed.
71571	LRR domain-mediated complex assembly	P	A process of protein complex assembly in which the arrangement and bonding together of the set of components that form the protein complex is mediated by an LRR (leucine-rich repeat) domain interaction.
71572	histone H3-K56 deacetylation	P	The modification of histone H3 by the removal of an acetyl group from lysine at position 56 of the histone.
71573	telosome assembly	P	The aggregation, arrangement and bonding together of a set of components to form a telosome. A telosome is a nuclear telomere cap complex that is formed by the association of telomeric ssDNA- and dsDNA-binding proteins with telomeric DNA, and is involved in telomere protection and recruitment of telomerase.
71574	protein localization to medial cortex	P	A process in which a protein is transported to, or maintained in, the medial cortex.
71575	integral component of external side of plasma membrane	C	The component of the plasma membrane consisting of the gene products that penetrate only the external side of the membrane.
71576	tetrahydrodictyopterin binding	F	Interacting selectively and non-covalently with tetrahydrodictyopterin, the pterin 2-amino-6-[(1R,2R)-1,2-dihydroxypropyl]-5,6,7,8-tetrahydropteridin-4(3H)-one.
71577	zinc II ion transmembrane transport	P	A process in which a zinc II ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.
71578	zinc II ion transmembrane import	P	The directed movement of zinc II ions across a membrane into a cell or organelle.
71579	regulation of zinc ion transport	P	Any process that modulates the frequency, rate or extent of the directed movement of zinc ions (Zn2+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
71580	regulation of zinc ion transmembrane transport	P	Any process that modulates the frequency, rate or extent of the directed movement of zinc ions (Zn2+) from one side of a membrane to the other.
71581	regulation of zinc ion transmembrane import	P	Any process that modulates the frequency, rate or extent of zinc ion import.
71582	negative regulation of zinc ion transport	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of zinc ions (Zn2+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
71583	negative regulation of zinc ion transmembrane transport	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of zinc ions (Zn2+) from one side of a membrane to the other.
71584	negative regulation of zinc ion transmembrane import	P	Any process that stops, prevents, or reduces the frequency, rate or extent of zinc ion import.
71585	detoxification of cadmium ion	P	Any process that reduces or removes the toxicity of cadmium ion. These may include transport of cadmium away from sensitive areas and to compartments or complexes whose purpose is sequestration of cadmium ion.
71586	CAAX-box protein processing	P	The second process in a series of specific posttranslational modifications to the CAAX box region of CAAX box proteins, in which the last three amino acids of the protein (AAX) are removed by proteolysis.
71587	CAAX-box protein modification	P	The covalent alteration of one or more amino acid residues within the CAAX box region of CAAX box proteins.
71588	hydrogen peroxide mediated signaling pathway	P	A series of molecular signals mediated by the detection of hydrogen peroxide (H2O2).
71589	pyridine nucleoside biosynthetic process	P	The chemical reactions and pathways resulting in the formation of any pyridine nucleoside, one of a family of organic molecules consisting of a pyridine base covalently bonded to a sugar, usually ribose.
71590	nicotinamide riboside biosynthetic process	P	The chemical reactions and pathways resulting in the formation of nicotinamide riboside, the product of the formation of a glycosidic bond between ribose and nicotinamide.
71591	nicotinic acid riboside metabolic process	P	The chemical reactions and pathways involving nicotinic acid riboside, the product of the formation of a glycosidic bond between ribose and nicotinic acid.
71592	nicotinic acid riboside biosynthetic process	P	The chemical reactions and pathways resulting in the formation of nicotinic acid riboside, the product of the formation of a glycosidic bond between ribose and nicotinic acid.
71593	lymphocyte aggregation	P	The adhesion of one lymphocyte to one or more other lymphocytes via adhesion molecules.
71594	thymocyte aggregation	P	The adhesion of one thymocyte (an immature T cell) to one or more other thymocytes via adhesion molecules.
71595	Nem1-Spo7 phosphatase complex	C	A protein serine/threonine phosphatase complex that is involved in nuclear envelope organization, and contains proteins known in budding yeast as Nem1p and Spo7p.
71596	ubiquitin-dependent protein catabolic process via the N-end rule pathway	P	The chemical reactions and pathways resulting in the breakdown of a protein or peptide covalently tagged with ubiquitin, via the N-end rule pathway. In the N-end rule pathway, destabilizing N-terminal residues (N-degrons) in substrates are recognized by E3 ligases (N-recognins), whereupon the substrates are linked to ubiquitin and then delivered to the proteasome for degradation.
71597	cellular birth scar	C	Crater-like ring of chitinous scar tissue located on the surface of the daughter cell, in budding fungi, at the site of separation from the mother cell. It is formed after the newly emerged daughter cell separates, thereby marking the site of cytokinesis and septation.
71598	neuronal ribonucleoprotein granule	C	A ribonucleoprotein complex that is found in the cytoplasm of axons and dendrites, and transports translationally silenced mRNAs to dendritic synapses, where they are released and translated in response to specific exogenous stimuli.
71599	otic vesicle development	P	The process whose specific outcome is the progression of the otic vesicle over time, from its formation to the mature structure. The otic vesicle is a transient embryonic structure formed during development of the vertebrate inner ear.
71600	otic vesicle morphogenesis	P	The process in which the anatomical structures of the otic vesicle are generated and organized. The otic vesicle is a transient embryonic structure formed during development of the vertebrate inner ear.
71601	sphere organelle	C	A nuclear body that is found in the germinal vesicles of amphibian oocytes, and consist of three major parts: a remarkably spherical body about 5-10 pm in diameter, smaller spherical or nearly spherical granules on the surface, and inclusions of various sizes that strongly resemble the surface granules. The parts of the sphere organelle have distinct compositions, including splicing snRNAs and proteins.
71602	phytosphingosine biosynthetic process	P	The chemical reactions and pathways resulting in the formation of phytosphingosine, (2S,3S,4R)-2-aminooctadecane-1,3,4-triol.
71603	endothelial cell-cell adhesion	P	The attachment of an endothelial cell to another endothelial cell via adhesion molecules.
71604	transforming growth factor beta production	P	The appearance of any member of the transforming growth factor-beta family of cytokines due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels. Transforming growth factor-beta family members include TGF-B1, TGF-B2, and TGF-B3.
71605	monocyte chemotactic protein-1 production	P	The appearance of monocyte chemotactic protein-1 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
71606	chemokine (C-C motif) ligand 4 production	P	The appearance of chemokine (C-C motif) ligand 4 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
71607	macrophage inflammatory protein-1 gamma production	P	The appearance of macrophage inflammatory protein-1 gamma due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
71608	macrophage inflammatory protein-1 alpha production	P	The appearance of macrophage inflammatory protein 1 alpha due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
71609	chemokine (C-C motif) ligand 5 production	P	The appearance of chemokine (C-C motif) ligand 5 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
71610	chemokine (C-C motif) ligand 1 production	P	The appearance of chemokine (C-C motif) ligand 1 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
71611	granulocyte colony-stimulating factor production	P	The appearance of granulocyte colony-stimulating factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
71612	IP-10 production	P	The appearance of IP-10 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
71613	granzyme B production	P	The appearance of granzyme B due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
71614	linoleic acid epoxygenase activity	F	Catalysis of an NADPH- and oxygen-dependent reaction that converts linoleic acid to a cis-epoxyoctadecenoic acid.
71615	oxidative deethylation	P	The process of removing one or more ethyl groups from a molecule, involving the oxidation (i.e. electron loss) of one or more atoms in the substrate.
71616	acyl-CoA biosynthetic process	P	The chemical reactions and pathways resulting in the formation of acyl-CoA, any derivative of coenzyme A in which the sulfhydryl group is in thiolester linkage with an acyl group.
71617	lysophospholipid acyltransferase activity	F	Catalysis of the transfer of acyl groups from an acyl-CoA to a lysophospholipid.
71618	lysophosphatidylethanolamine acyltransferase activity	F	Catalysis of the transfer of acyl groups from an acyl-CoA to lysophosphatidylethanolamine.
71619	phosphorylation of RNA polymerase II C-terminal domain serine 2 residues	P	The process of introducing a phosphate group onto a serine residue at position 2 within the heptapeptide repeat (YSPTSPS) of the C-terminal domain of RNA polymerase II. Typically, phosphorylation of serine 2 (Ser2) occurs subsequent to phosphorylation of serine 5 and is thus seen in the middle and 3' ends of genes. In vivo, Ser2 phosphorylation is primarily performed by CTDK-I in S. cerevisiae or CDK9 in metazoans.
71620	phosphorylation of RNA polymerase II C-terminal domain serine 5 residues	P	The process of introducing a phosphate group onto a serine residue at position 5 within the heptapeptide repeat (YSPTSPS) of the C-terminal domain of RNA polymerase II. Typically, phosphorylation of serine 5 (Ser5) occurs near the 5' ends of genes. It is generally still observed in the middle of genes, overlapping with phosphorylation of serine 2, but is generally not present at the 3' ends of genes. In vivo, Ser5 phosphorylation occurs primarily through the action of TFIIH (KIN28 in S. cerevisiae, CKD7 in metazoans).
71621	granulocyte chemotaxis	P	The movement of a granulocyte in response to an external stimulus.
71622	regulation of granulocyte chemotaxis	P	Any process that modulates the rate, frequency or extent of granulocyte chemotaxis. Granulocyte chemotaxis is the movement of a granulocyte in response to an external stimulus.
71623	negative regulation of granulocyte chemotaxis	P	Any process that decreases the rate, frequency or extent of granulocyte chemotaxis. Granulocyte chemotaxis is the movement of a granulocyte in response to an external stimulus.
71624	positive regulation of granulocyte chemotaxis	P	Any process that increases the rate, frequency or extent of granulocyte chemotaxis. Granulocyte chemotaxis is the movement of a granulocyte in response to an external stimulus.
71625	vocalization behavior	P	The behavior in which an organism produces sounds by a mechanism involving its respiratory system.
71626	mastication	P	The process of biting and mashing food with the teeth prior to swallowing.
71627	integral component of fungal-type vacuolar membrane	C	The component of the fungal-type vacuole membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
71628	intrinsic component of fungal-type vacuolar membrane	C	The component of a fungal-type vacuole membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.
71629	ubiquitin-dependent catabolism of misfolded proteins by cytoplasm-associated proteasome	P	The chemical reactions and pathways resulting in the breakdown of misfolded proteins in the cytoplasm, which are targeted to cytoplasmic proteasomes for degradation.
71630	ubiquitin-dependent catabolism of misfolded proteins by nucleus-associated proteasome	P	The chemical reactions and pathways resulting in the breakdown of misfolded proteins via a mechanism in which the proteins are transported to the nucleus for ubiquitination, and then targeted to proteasomes for degradation.
71631	mating pheromone secretion involved in conjugation with cellular fusion	P	The regulated release of a mating pheromone, a peptide hormone that induces a behavioral or physiological response(s) from a responding organism or cell, that contributes to a conjugation process that results in the union of cellular and genetic information from compatible mating types.
71632	optomotor response	P	Eye, head or whole body movements that help to compensate movements of the environment in order to stabilize its image on the retina. In the case of whole body movements, these motor actions may also stabilize a locomotor course in response to some disturbance. Examples include: the optokinetic reflex, which allows human eyes to follow objects in motion while the head remains stationary reflex; the optomotor responses of flying insects and swimming fish.
71633	dihydroceramidase activity	F	Catalysis of the reaction: a dihydroceramide + H2O = a fatty acid + dihydrosphingosine.
71634	regulation of transforming growth factor beta production	P	Any process that modulates the frequency, rate, or extent of production of transforming growth factor-beta.
71635	negative regulation of transforming growth factor beta production	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of production of transforming growth factor-beta.
71636	positive regulation of transforming growth factor beta production	P	Any process that activates or increases the frequency, rate, or extent of production of transforming growth factor-beta.
71637	regulation of monocyte chemotactic protein-1 production	P	Any process that modulates the frequency, rate, or extent of production of monocyte chemotactic protein-1.
71638	negative regulation of monocyte chemotactic protein-1 production	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of production of monocyte chemotactic protein-1.
71639	positive regulation of monocyte chemotactic protein-1 production	P	Any process that activates or increases the frequency, rate, or extent of production of monocyte chemotactic protein-1.
71640	regulation of macrophage inflammatory protein 1 alpha production	P	Any process that modulates the frequency, rate, or extent of production of macrophage inflammatory protein 1 alpha.
71641	negative regulation of macrophage inflammatory protein 1 alpha production	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of production of macrophage inflammatory protein 1 alpha.
71642	positive regulation of macrophage inflammatory protein 1 alpha production	P	Any process that activates or increases the frequency, rate, or extent of production of macrophage inflammatory protein 1 alpha.
71643	regulation of chemokine (C-C motif) ligand 4 production	P	Any process that modulates the frequency, rate, or extent of production of chemokine (C-C motif) ligand 4.
71644	negative regulation of chemokine (C-C motif) ligand 4 production	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of production of chemokine (C-C motif) ligand 4.
71645	positive regulation of chemokine (C-C motif) ligand 4 production	P	Any process that activates or increases the frequency, rate, or extent of production of chemokine (C-C motif) ligand 4.
71646	regulation of macrophage inflammatory protein-1 gamma production	P	Any process that modulates the frequency, rate, or extent of production of macrophage inflammatory protein-1 gamma.
71647	negative regulation of macrophage inflammatory protein-1 gamma production	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of production of macrophage inflammatory protein-1 gamma.
71648	positive regulation of macrophage inflammatory protein-1 gamma production	P	Any process that activates or increases the frequency, rate, or extent of production of macrophage inflammatory protein-1 gamma.
71649	regulation of chemokine (C-C motif) ligand 5 production	P	Any process that modulates the frequency, rate, or extent of production of chemokine (C-C motif) ligand 5.
71650	negative regulation of chemokine (C-C motif) ligand 5 production	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of production of chemokine (C-C motif) ligand 5.
71651	positive regulation of chemokine (C-C motif) ligand 5 production	P	Any process that activates or increases the frequency, rate, or extent of production of chemokine (C-C motif) ligand 5.
71652	regulation of chemokine (C-C motif) ligand 1 production	P	Any process that modulates the frequency, rate, or extent of production of chemokine (C-C motif) ligand 1.
71653	negative regulation of chemokine (C-C motif) ligand 1 production	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of production of chemokine (C-C motif) ligand 1.
71654	positive regulation of chemokine (C-C motif) ligand 1 production	P	Any process that activates or increases the frequency, rate, or extent of production of chemokine (C-C motif) ligand 1.
71655	regulation of granulocyte colony-stimulating factor production	P	Any process that modulates the frequency, rate, or extent of production of granulocyte colony-stimulating factor.
71656	negative regulation of granulocyte colony-stimulating factor production	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of production of granulocyte colony stimulating factor.
71657	positive regulation of granulocyte colony-stimulating factor production	P	Any process that activates or increases the frequency, rate, or extent of production of granulocyte colony-stimulating factor.
71658	regulation of IP-10 production	P	Any process that modulates the frequency, rate, or extent of production of IP-10.
71659	negative regulation of IP-10 production	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of production of IP-10.
71660	positive regulation of IP-10 production	P	Any process that activates or increases the frequency, rate, or extent of production of IP-10.
71661	regulation of granzyme B production	P	Any process that modulates the frequency, rate, or extent of production of granzyme B.
71662	negative regulation of granzyme B production	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of production of granzyme B.
71663	positive regulation of granzyme B production	P	Any process that activates or increases the frequency, rate, or extent of production of granzyme B.
71664	catenin-TCF7L2 complex	C	A protein complex that contains a catenin and TCF7L2 (TCF4), binds to the TCF DNA motif within a promoter element, and is involved in the regulation of WNT target gene transcription.
71665	gamma-catenin-TCF7L2 complex	C	A protein complex that contains gamma-catenin and TCF7L2 (TCF4), binds to the TCF DNA motif within a promoter element, and is involved in the regulation of WNT target gene transcription.
71666	Slit-Robo signaling complex	C	A protein-carbohydrate complex that consists of a transmembrane roundabout (Robo) receptor, an extracellular Slit ligand and heparin/heparan sulfate.
71667	DNA/RNA hybrid binding	F	Interacting selectively and non-covalently with a RNA/DNA hybrid.
71668	plant-type cell wall assembly	P	The aggregation, arrangement and bonding together of a set of components to form a cellulose- and pectin-containing cell wall.
71669	plant-type cell wall organization or biogenesis	P	A process that results in the biosynthesis of constituent macromolecules, assembly, arrangement of constituent parts, or disassembly of a cellulose- and pectin-containing cell wall.
71670	smooth muscle cell chemotaxis	P	The directed movement of a smooth muscle cell in response to an external stimulus.
71671	regulation of smooth muscle cell chemotaxis	P	Any process that modulates the frequency, rate, or extent of smooth muscle cell chemotaxis.
71672	negative regulation of smooth muscle cell chemotaxis	P	Any process that stops, prevents, or reduces the frequency, rate, or extent of smooth muscle cell chemotaxis.
71673	positive regulation of smooth muscle cell chemotaxis	P	Any process that activates or increases the frequency, rate, or extent of smooth muscle cell chemotaxis.
71674	mononuclear cell migration	P	The movement of a mononuclear cell within or between different tissues and organs of the body.
71675	regulation of mononuclear cell migration	P	Any process that modulates the rate, frequency or extent of mononuclear cell migration. Mononuclear cell migration is the movement of a mononuclear cell within or between different tissues and organs of the body.
71676	negative regulation of mononuclear cell migration	P	Any process that decreases the rate, frequency or extent of mononuclear cell migration. Mononuclear cell migration is the movement of a mononuclear cell within or between different tissues and organs of the body.
71677	positive regulation of mononuclear cell migration	P	Any process that increases the rate, frequency or extent of mononuclear cell migration. Mononuclear cell migration is the movement of a mononuclear cell within or between different tissues and organs of the body.
71678	olfactory bulb axon guidance	P	The process in which the migration of an axon growth cone of a neuron in the olfactory bulb is directed to its target in the brain in response to a combination of attractive and repulsive cues.
71679	commissural neuron axon guidance	P	The process in which the migration of an axon growth cone of a commissural neuron is directed to its target in the brain in response to a combination of attractive and repulsive cues.
71680	response to indole-3-methanol	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an indole-3-methanol stimulus.
71681	cellular response to indole-3-methanol	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an indole-3-methanol stimulus.
71682	endocytic vesicle lumen	C	The volume enclosed by the membrane of an endocytic vesicle.
71683	sensory dendrite	C	A dendrite that is found on a sensory neuron, and directly transduces a sensory signal from the sensory neuron to another neuron.
71684	organism emergence from protective structure	P	The developmental process in which an organism emerges from a surrounding protective structure such as an egg or pupa case.
71685	NADH dehydrogenase complex (plastoquinone)	C	An NADH dehydrogenase complex that catalyzes the transfer of electrons to plastoquinone. The complex is involved in the non-photochemical reduction of plastoquinones and the cyclic electron transport around photosystem I, and is found in plastid thylakoids.
71686	horsetail nucleus	C	The elongated nucleus which forms during the rapid oscillatory movement at meiotic prophase; characterized in Schizosaccharomyces pombe.
71687	horsetail nucleus leading edge	C	The part of the horsetail nucleus where telomeres cluster under the SPB and that leads horsetail movement. The horsetail nucleus is the elongated nucleus which forms during the rapid oscillatory movement at meiotic prophase; characterized in Schizosaccharomyces pombe.
71688	striated muscle myosin thick filament assembly	P	The aggregation, arrangement and bonding together of proteins to form the myosin-based thick filaments of myofibrils in striated muscle.
71689	muscle thin filament assembly	P	The aggregation, arrangement and bonding together of proteins to form the actin-based thin filaments of myofibrils in striated muscle.
71690	cardiac muscle myosin thick filament assembly	P	The aggregation, arrangement and bonding together of proteins to form the myosin-based thick filaments of myofibrils in cardiac muscle.
71691	cardiac muscle thin filament assembly	P	The aggregation, arrangement and bonding together of proteins to form the actin-based thin filaments of myofibrils in cardiac muscle.
71692	protein localization to extracellular region	P	Any process in which a protein is transported from one specific location in the extracellular region to another, or maintained in a specific extracellular location.
71693	protein transport within extracellular region	P	The directed movement of proteins in the extracellular region, by means of some agent such as a transporter or pore.
71694	maintenance of protein location in extracellular region	P	Any process in which a protein is maintained in a specific location within the extracellular region and is prevented from moving elsewhere.
71695	anatomical structure maturation	P	A developmental process, independent of morphogenetic (shape) change, that is required for an anatomical structure to attain its fully functional state.
71696	ectodermal placode development	P	The progression of an ectodermal placode over time from its initial formation until its mature state. An ectodermal placode is a thickening of the ectoderm that is the primordium of many structures derived from the ectoderm.
71697	ectodermal placode morphogenesis	P	The process in which the anatomical structures of an ectodermal placode are generated and organized. An ectodermal placode is a thickening of the ectoderm that is the primordium of many structures derived from the ectoderm.
71698	olfactory placode development	P	The progression of the olfactory placode over time from its initial formation until its mature state. The olfactory placode is a thickening of the neural ectoderm in the head region of the vertebrate embryo which develops into the olfactory region of the nasal cavity.
71699	olfactory placode morphogenesis	P	The process in which the anatomical structures of the olfactory placode are generated and organized. The olfactory placode is a thickening of the neural ectoderm in the head region of the vertebrate embryo which develops into the olfactory region of the nasal cavity.
71700	olfactory placode maturation	P	A developmental process, independent of morphogenetic (shape) change, that is required for the olfactory placode to attain its fully functional state. The olfactory placode is a thickening of the neural ectoderm in the head region of the vertebrate embryo which develops into the olfactory region of the nasal cavity.
71701	regulation of MAPK export from nucleus	P	Any process that modulates the frequency, rate or extent of the directed movement of a MAP kinase from the nucleus to the cytoplasm.
71702	organic substance transport	P	The directed movement of organic substances into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter or pore. An organic substance is a molecular entity that contains carbon.
71703	detection of organic substance	P	The series of events in which an organic substance stimulus is received by a cell and converted into a molecular signal.
71704	organic substance metabolic process	P	The chemical reactions and pathways involving an organic substance, any molecular entity containing carbon.
71705	nitrogen compound transport	P	The directed movement of nitrogen-containing compounds into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
71706	tumor necrosis factor superfamily cytokine production	P	The appearance of any member of the TNF superfamily due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
71707	immunoglobulin heavy chain V-D-J recombination	P	The process in which immunoglobulin heavy chain V, D, and J gene segments are recombined within a single locus utilizing the conserved heptamer and nonomer recombination signal sequences (RSS).
71708	immunoglobulin light chain V-J recombination	P	The process in which immunoglobulin light chain V and J gene segments are recombined within a single locus utilizing the conserved heptamer and nonomer recombination signal sequences (RSS).
71709	membrane assembly	P	The aggregation, arrangement and bonding together of a set of components to form a membrane.
71710	membrane macromolecule biosynthetic process	P	The chemical reactions and pathways resulting in the formation of a macromolecule destined to form part of a membrane in a cell.
71711	basement membrane organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the basement membrane.
71712	ER-associated misfolded protein catabolic process	P	The chemical reactions and pathways resulting in the breakdown of misfolded proteins transported from the endoplasmic reticulum and targeted to cytoplasmic proteasomes for degradation.
71713	para-aminobenzoyl-glutamate hydrolase activity	F	Catalysis of the reaction: para-aminobenzoyl-glutamate + H2O = para-aminobenzoate + L-glutamate.
71714	icosanoid transmembrane transporter activity	F	Enables the transfer of icosanoids from one side of the membrane to the other.
71715	icosanoid transport	P	The directed movement of icosanoids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Icosanoids are unsaturated C20 fatty acids and skeletally related compounds.
71716	leukotriene transport	P	The directed movement of leukotrienes into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Leukotrienes are linear C20 endogenous metabolites of arachidonic acid (icosa-5,8,11,14-tetraenoic acid) containing a terminal carboxy function and four or more double bonds (three or more of which are conjugated) as well as other functional groups.
71717	thromboxane transport	P	The directed movement of thromboxanes into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A thromboxane is any of a class of oxygenated oxane derivatives, originally derived from prostaglandin precursors in platelets, that stimulate aggregation of platelets and constriction of blood vessels.
71718	sodium-independent icosanoid transport	P	The directed, sodium-independent, movement of icosanoids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Icosanoids are unsaturated C20 fatty acids and skeletally related compounds.
71719	sodium-independent leukotriene transport	P	The directed, sodium-independent, movement of leukotrienes into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Leukotrienes are linear C20 endogenous metabolites of arachidonic acid (icosa-5,8,11,14-tetraenoic acid) containing a terminal carboxy function and four or more double bonds (three or more of which are conjugated) as well as other functional groups.
71720	sodium-independent prostaglandin transport	P	The directed, sodium-independent, movement of prostaglandins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
71721	sodium-independent thromboxane transport	P	The directed, sodium-independent, movement of thromboxanes into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. A thromboxane is any of a class of oxygenated oxane derivatives, originally derived from prostaglandin precursors in platelets, that stimulate aggregation of platelets and constriction of blood vessels.
71722	detoxification of arsenic-containing substance	P	Any process that reduces or removes the toxicity of compounds containing arsenic, including arsenates, arsenites, and arsenides. These include transport of such compounds away from sensitive areas and to compartments or complexes whose purpose is sequestration of arsenic or arsenic-containing compounds.
71723	lipopeptide binding	F	Interacting selectively and non-covalently with a lipopeptide, any of a group of organic compounds comprising two or more amino acids linked by peptide bonds and containing a nonprotein group consisting of a lipid or lipids.
71724	response to diacyl bacterial lipopeptide	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diacylated bacterial lipopeptide stimulus.
71725	response to triacyl bacterial lipopeptide	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a triacylated bacterial lipopeptide stimulus.
71726	cellular response to diacyl bacterial lipopeptide	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diacylated bacterial lipopeptide stimulus.
71727	cellular response to triacyl bacterial lipopeptide	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a triacylated bacterial lipopeptide stimulus.
71728	beak development	P	The progression of the beak over time from its initial formation until its mature state. The avian beak is an external anatomical structure, in the head region, that is adapted for feeding self and young, catching prey, probing, etc. It encompasses, but is not restricted to, the maxilla, mandible, maxillary rhamphotheca, mandibular rhamphotheca, nostril, nasal fossa, nasal bones, egg tooth and rictus.
71729	beak morphogenesis	P	The process in which the anatomical structures of the beak are generated and organized. The avian beak is an external anatomical structure, in the head region, that is adapted for feeding self and young, catching prey, probing, etc. It encompasses, but is not restricted to, the maxilla, mandible, maxillary rhamphotheca, mandibular rhamphotheca, nostril, nasal fossa, nasal bones, egg tooth and rictus.
71730	beak formation	P	The process that gives rise to the beak. This process pertains to the initial formation of a structure from unspecified parts. The avian beak is an external anatomical structure, in the head region, that is adapted for feeding self and young, catching prey, probing, etc. It encompasses, but is not restricted to, the maxilla, mandible, maxillary rhamphotheca, mandibular rhamphotheca, nostril, nasal fossa, nasal bones, egg tooth and rictus.
71731	response to nitric oxide	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitric oxide stimulus.
71732	cellular response to nitric oxide	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitric oxide stimulus.
71733	transcriptional activation by promoter-enhancer looping	P	The formation and maintenance of DNA loops that juxtapose the promoter and enhancer regions of RNA polymerase II-transcribed genes and activate transcription from an RNA polymerase II promoter.
71734	biotin-[pyruvate-carboxylase] ligase activity	F	Catalysis of the reaction: ATP + biotin + apo-(pyruvate-carboxylase) = AMP + diphosphate + biotin-(pyruvate-carboxylase).
71735	IgG immunoglobulin complex	C	A protein complex composed of two identical immunoglobulin heavy chains of an IgG isotype and two identical immunoglobulin light chains, held together by disulfide bonds. An IgG immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.
71736	IgG immunoglobulin complex, circulating	C	A protein complex composed of two identical immunoglobulin heavy chains of an IgG isotype and two identical immunoglobulin light chains, held together by disulfide bonds, and present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.
71737	IgG B cell receptor complex	C	An IgG immunoglobulin complex that is present in the plasma membrane of B cells and is composed of two identical immunoglobulin heavy chains of an IgG isotype and two identical immunoglobulin light chains and a signaling subunit, a heterodimer of the Ig-alpha and Ig-beta proteins.
71738	IgD immunoglobulin complex	C	A protein complex composed of two identical immunoglobulin heavy chains of the IgD isotype and two identical immunoglobulin light chains, held together by disulfide bonds. An IgD immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.
71739	IgD immunoglobulin complex, circulating	C	A protein complex composed of two identical immunoglobulin heavy chains of the IgD isotype and two identical immunoglobulin light chains, held together by disulfide bonds, and present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.
71740	IgD B cell receptor complex	C	An IgD immunoglobulin complex that is present in the plasma membrane of B cells and is composed of two identical immunoglobulin heavy chains of the IgD isotype and two identical immunoglobulin light chains and a signaling subunit, a heterodimer of the Ig-alpha and Ig-beta proteins.
71741	IgD immunoglobulin complex, GPI-anchored	C	A protein complex composed of two identical immunoglobulin heavy chains of the IgD isotype and two identical immunoglobulin light chains, held together by disulfide bonds, and bound via a GPI-anchor to the plasma membrane of B cells.
71742	IgE immunoglobulin complex	C	A protein complex composed of two identical immunoglobulin heavy chains of the IgE isotype and two identical immunoglobulin light chains, held together by disulfide bonds. An IgE immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.
71743	IgE immunoglobulin complex, circulating	C	A protein complex composed of two identical immunoglobulin heavy chains of the IgE isotype and two identical immunoglobulin light chains, held together by disulfide bonds, and present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.
71744	IgE B cell receptor complex	C	An IgE immunoglobulin complex that is present in the plasma membrane of B cells and is composed of two identical immunoglobulin heavy chains of the IgE isotype and two identical immunoglobulin light chains and a signaling subunit, a heterodimer of the Ig-alpha and Ig-beta proteins.
71745	IgA immunoglobulin complex	C	A protein complex composed of two identical immunoglobulin heavy chains of the IgA isotype and two identical immunoglobulin light chains, held together by disulfide bonds, and sometimes complexed with J chain or J chain and secretory component. An IgA immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.
71746	IgA immunoglobulin complex, circulating	C	A protein complex composed of two identical immunoglobulin heavy chains of an IgA isotype and two identical immunoglobulin light chains, held together by disulfide bonds, sometimes complexed with J chain or J chain and secretory component, and present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.
71747	IgA B cell receptor complex	C	An IgA immunoglobulin complex that is present in the plasma membrane of B cells and is composed of two identical immunoglobulin heavy chains of an IgA isotype and two identical immunoglobulin light chains and a signaling subunit, a heterodimer of the Ig-alpha and Ig-beta proteins.
71748	monomeric IgA immunoglobulin complex	C	A protein complex composed of two identical immunoglobulin heavy chains of an IgA isotype and two identical immunoglobulin light chains, held together by disulfide bonds, and present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.
71749	polymeric IgA immunoglobulin complex	C	A protein complex composed of two, three, or four monomeric IgA immunoglobulin complexes linked through both direct disulfide bonds and through disulfide binded monomers of J chain acting as a bridge. Each IgA monomer consists of two identical immunoglobulin heavy chains of an IgA isotype and two identical immunoglobulin light chains, held together by disulfide bonds. Dimeric IgA is sometimes complexed additionally with secretory component, and present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.
71750	dimeric IgA immunoglobulin complex	C	A protein complex composed of two monomeric IgA immunoglobulin complexes linked through both direct disulfide bonds and through a disulfide binded monomer of J chain acting as a bridge. Each IgA monomer consists of two identical immunoglobulin heavy chains of an IgA isotype and two identical immunoglobulin light chains, held together by disulfide bonds. Dimeric IgA is sometimes complexed additionally with secretory component, and present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.
71751	secretory IgA immunoglobulin complex	C	A polymeric IgA immunoglobulin complex that is complexed with one chain of secretory component (SC). Polymeric IgA is present in mucosal areas, having been transported via a transcytosis mechanism in mucosal epithelial cells relying on the polymeric Ig receptor, a portion of which then remains bound to the polymeric IgA as secretory component.
71752	secretory dimeric IgA immunoglobulin complex	C	A dimeric form of secretory IgA immunoglobulin complex.
71753	IgM immunoglobulin complex	C	A protein complex composed of two identical immunoglobulin heavy chains of the IgM isotype and two identical immunoglobulin light chains, held together by disulfide bonds, and in its circulating form complexed with J chain in polymeric forms. An IgM immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.
71754	IgM immunoglobulin complex, circulating	C	A polymer of five or six IgM core units each composed of two identical immunoglobulin heavy chains of the IgM isotype and two identical immunoglobulin light chains, held together by disulfide bonds; the individual IgM core units are held together via disulfide bonds with a single J chain polypeptide acting as a bridge between two of the polymeric units. Circulating IgM is present in the extracellular space, in mucosal areas or other tissues, or in the blood or lymph.
71755	IgM B cell receptor complex	C	An IgM immunoglobulin complex that is present in the plasma membrane of B cells and is composed of two identical immunoglobulin heavy chains of the IgM isotype and two identical immunoglobulin light chains and a signaling subunit, a heterodimer of the Ig-alpha and Ig-beta proteins.
71756	pentameric IgM immunoglobulin complex	C	A circulating form of IgM consisting of a pentamer of IgM core units with a single J chain polypeptide.
71757	hexameric IgM immunoglobulin complex	C	A circulating form of IgM consisting of a hexamer of IgM core units with a single J chain polypeptide.
71758	IgW immunoglobulin complex	C	A protein complex composed of two identical immunoglobulin heavy chains of the IgW isotype and two identical immunoglobulin light chains, held together by disulfide bonds. An IgW immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.
71759	IgX immunoglobulin complex	C	A protein complex composed of two identical immunoglobulin heavy chains of the IgX isotype and two identical immunoglobulin light chains, held together by disulfide bonds. An IgX immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.
71760	IgY immunoglobulin complex	C	A protein complex composed of two identical immunoglobulin heavy chains of the IgY isotype and two identical immunoglobulin light chains, held together by disulfide bonds. An IgY immunoglobulin complex may be embedded in the plasma membrane or present in the extracellular space, in mucosal areas or other tissues, or circulating in the blood or lymph.
71761	IgZ immunoglobulin complex	C	A protein complex composed of two identical immunoglobulin heavy chains of the IgZ isotype and two identical immunoglobulin light chains, held together by disulfide bonds. The IgZ isotype is also known as the IgT isotype in certain species of fish.
71762	heavy chain immunoglobulin complex	C	A protein complex composed of two identical immunoglobulin heavy chains of the IgNAR isotype held together by disulfide bonds and lacking immunoglobulin light chains.
71763	nuclear membrane organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear inner or outer membrane.
71764	nuclear outer membrane organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear outer membrane.
71765	nuclear inner membrane organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear inner membrane.
71766	Actinobacterium-type cell wall biogenesis	P	A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a cell wall of the type found in Actinobacteria. The cell wall is the rigid or semi-rigid envelope lying outside the cell membrane. Actinobacterial cell walls contain characteristic mycolic acids, of which some are covalently linked to the cell wall peptidoglycan and others accumulate at the cell surface.
71767	mycolic acid metabolic process	P	The chemical reactions and pathways involving mycolic acids, beta-hydroxy fatty acids with a long alpha-alkyl side chain.
71768	mycolic acid biosynthetic process	P	The chemical reactions and pathways resulting in the formation of mycolic acids, beta-hydroxy fatty acids with a long alpha-alkyl side chain.
71769	mycolate cell wall layer assembly	P	The aggregation, arrangement and bonding together of a set of components, including arabinogalactan mycolate and trehalose dimycolate, to form the mycolate layer of the Actinobacterium-type cell wall. The mycolate layer is physically attached to the peptidoglycan layer.
71770	DIM/DIP cell wall layer assembly	P	The aggregation, arrangement and bonding together of a set of components, including (phenyl)phthiocerol, phthiodiolone, phthiotriol dimycocerosate and diphthioceranate, to form the DIM/DIP layer of the Actinobacterium-type cell wall.
71771	aldehyde decarbonylase activity	F	Catalysis of the reaction: a C(n) aldehyde = C(n-1) alkane + CO.
71772	response to BMP	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bone morphogenetic protein (BMP) stimulus.
71773	cellular response to BMP stimulus	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bone morphogenetic protein (BMP) stimulus.
71774	response to fibroblast growth factor	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fibroblast growth factor stimulus.
71781	endoplasmic reticulum cisternal network	C	A subcompartment of the endoplasmic reticulum consisting of flattened, disc-shaped domains known as cisternae. These are typically found close to the nucleus and are generally more prominent in secretory cells.
71782	endoplasmic reticulum tubular network	C	A subcompartment of the endoplasmic reticulum consisting of tubules having membranes with high curvature in cross-section.
71783	endoplasmic reticulum cisternal network organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the endoplasmic reticulum (ER) cisternal network. The ER cisternal network is the ER part that comprises the membranes with low curvature in cross-section.
71784	endoplasmic reticulum cisternal network assembly	P	The aggregation, arrangement and bonding together of a set of components to form the endoplasmic reticulum (ER) cisternal network. The ER cisternal network is the ER part that comprises the membranes with low curvature in cross-section.
71785	endoplasmic reticulum cisternal network maintenance	P	The organization process that preserves the endoplasmic reticulum (ER) cisternal network in a stable functional or structural state. The ER cisternal network is the ER part that comprises the membranes with low curvature in cross-section.
71786	endoplasmic reticulum tubular network organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the endoplasmic reticulum (ER) tubular network. The ER tubular network is the ER part that that has membranes with high curvature in cross-section.
71787	endoplasmic reticulum tubular network assembly	P	The aggregation, arrangement and bonding together of a set of components to form the endoplasmic reticulum (ER) tubular network. The ER tubular network is the ER part that comprises the membranes with high curvature in cross-section.
71788	endoplasmic reticulum tubular network maintenance	P	The organization process that preserves the endoplasmic reticulum (ER) tubular network in a stable functional or structural state. The ER tubular network is the ER part that comprises the membranes with high curvature in cross-section.
71789	spindle pole body localization to nuclear envelope	P	A process in which a spindle pole body is transported to, or maintained in, a specific location in the nuclear envelope. A spindle pole body is a type of microtubule organizing center found in fungal cells.
71790	establishment of spindle pole body localization to nuclear envelope	P	A process in which a spindle pole body is transported to a specific location in the nuclear envelope. A spindle pole body is a type of microtubule organizing center found in fungal cells.
71791	chemokine (C-C motif) ligand 5 binding	F	Interacting selectively and non-covalently with chemokine (C-C motif) ligand 5.
71792	bacillithiol metabolic process	P	The chemical reactions and pathways involving bacillithiol, the alpha-anomeric glycoside of L-cysteinyl-D-glucosamine with L-malic acid. Bacillithiol, produced widely in the Firmicutes and sporadically in other bacterial lineages, is a low-molecular-weight thiol analogous to mycothiol in the Actinomycetes and glutathione in many species.
71793	bacillithiol biosynthetic process	P	The chemical reactions and pathways resulting in the formation of bacillithiol, the alpha-anomeric glycoside of L-cysteinyl-D-glucosamine with L-malic acid. Bacillithiol, produced widely in the Firmicutes and sporadically in other bacterial lineages, is a low-molecular-weight thiol analogous to mycothiol in the Actinomycetes and glutathione in many species.
71794	CAP-Gly domain binding	F	Interacting selectively and non-covalently with a CAP-Gly domain of a protein. The CAP_Gly domain is a conserved, glycine-rich domain of about 42 residues found in some cytoskeleton-associated proteins, and features a novel protein fold containing three beta-sheets.
71795	K11-linked polyubiquitin binding	F	Interacting selectively and non-covalently and non-covalently with a polymer of ubiquitin formed by linkages between lysine residues at position 11 of the ubiquitin monomers.
71796	K6-linked polyubiquitin binding	F	Interacting selectively and non-covalently and non-covalently with a polymer of ubiquitin formed by linkages between lysine residues at position 6 of the ubiquitin monomers.
71797	LUBAC complex	C	A ubiquitin ligase complex that catalyzes linear head-to-tail polyubiquitin conjugation on its targets. In human the complex consists of RBCK1, RNF31 and SHARPIN, and has an MW of approximately 600 kDa, suggesting a heteromultimeric assembly of its subunits. LUBAC stands for Linear Ubiquitin Chain Assembly Complex.
71798	response to prostaglandin D	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin D stimulus.
71799	cellular response to prostaglandin D stimulus	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prostagladin D stimulus.
71800	podosome assembly	P	The aggregation, arrangement and bonding together of a set of components to form a podosome, an actin-rich adhesion structure characterized by formation upon cell substrate contact and localization at the substrate-attached part of the cell.
71801	regulation of podosome assembly	P	Any process that modulates the frequency, rate or extent of podosome assembly.
71802	negative regulation of podosome assembly	P	Any process that stops, prevents or reduces the rate or extent of podosome assembly.
71803	positive regulation of podosome assembly	P	Any process that activates or increases the rate or extent of podosome assembly.
71804	cellular potassium ion transport	P	The directed movement of potassium (K) ions into, out of, or within a cell.
71805	potassium ion transmembrane transport	P	A process in which a potassium ion is transported from one side of a membrane to the other.
71806	protein transmembrane transport	P	The directed movement of a protein across a membrane by means of some agent such as a transporter or pore.
71807	replication fork arrest involved in DNA replication termination	P	A replication fork arrest process that contributes to the termination of DNA replication.
71808	satellite fibril	C	An axoneme part that is found in the flagella of mammalian sperm and is located in the middle piece between the outer dense fibers (on the concave side of outer dense fibers as seen in cross-section).
71809	regulation of fever generation by regulation of prostaglandin biosynthesis	P	Any process that modulates the rate or extent of fever generation via regulation of the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of prostaglandin.
71810	regulation of fever generation by regulation of prostaglandin secretion	P	Any process that modulates the rate or extent of fever generation via regulation of the frequency, rate or extent of the regulated release of a prostaglandin from a cell.
71811	positive regulation of fever generation by positive regulation of prostaglandin biosynthesis	P	Any process that increases the rate or extent of fever generation via positive regulation of the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of prostaglandin.
71812	positive regulation of fever generation by positive regulation of prostaglandin secretion	P	Any process that increases the rate or extent of fever generation via positive regulation of the frequency, rate or extent of the regulated release of a prostaglandin from a cell.
71813	lipoprotein particle binding	F	Interacting selectively and non-covalently with a lipoprotein particle. A lipoprotein particle, also known as a lipoprotein, is a clathrate complex consisting of a lipid enwrapped in a protein host without covalent binding in such a way that the complex has a hydrophilic outer surface consisting of all the protein and the polar ends of any phospholipids.
71814	protein-lipid complex binding	F	Interacting selectively and non-covalently with a protein-lipid complex, any macromolecular complex that contains both protein and lipid molecules.
71815	intermediate-density lipoprotein particle binding	F	Interacting selectively and non-covalently with a intermediate-density lipoprotein particle, a triglyceride-rich lipoprotein particle that typically contains APOB100, APOE and APOCs and has a density of 1.006-1.019 g/ml and a diameter of between 25-30 nm.
71816	tail-anchored membrane protein insertion into ER membrane	P	A process of protein insertion into the endoplasmic reticulum (ER) membrane in which a tail-anchored (TA) transmembrane protein is incorporated into an endoplasmic reticulum (ER) membrane. TA transmembrane protein, also named type II transmembrane proteins, contain a single C- terminal transmembrane region.
71817	MMXD complex	C	A protein complex that contains the proteins MMS19, MIP18 and XPD, localizes to mitotic spindle during mitosis, and is required for proper chromosome segregation.
71818	BAT3 complex	C	A protein complex consisting of BAT3 (BAG6) and its cofactors. In mammals these cofactors are TRC35 (GET4) and UBL4A. It facilitates tail-anchored protein capture by ASNA1/TRC4 and also chaperones polypeptides from the endoplasmic reticulum retrotranslocation machinery to the proteasome, maintaining the solubility of substrates to improve ER-associated protein degradation (ERAD).
71819	DUBm complex	C	A protein complex that forms part of SAGA-type complexes SAGA and SLIK, and mediates deubiquitination of histone H2B. In S. cerevisiae, the DUBm consists of the proteins Ubp8p, Sgf11p, Sus1p, and Sgf73p.
71820	N-box binding	F	Interacting selectively and non-covalently with an N-box, a DNA motif with the consensus sequence CACNAG that is found in the promoters of genes expressed preferentially at synapses.
71821	FANCM-MHF complex	C	A protein complex contains the proteins FANCM and MHF, or their orthologs, plays an essential role in DNA remodeling, protects replication forks, and is conserved in eukaryotes.
71822	protein complex subunit organization	P	Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a protein complex.
71823	protein-carbohydrate complex subunit organization	P	Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a protein-carbohydrate complex.
71824	protein-DNA complex subunit organization	P	Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a protein-DNA complex.
71825	protein-lipid complex subunit organization	P	Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a protein-lipid complex.
71826	ribonucleoprotein complex subunit organization	P	Any process in which macromolecules aggregate, disaggregate, or are modified, resulting in the formation, disassembly, or alteration of a ribonucleoprotein complex.
71827	plasma lipoprotein particle organization	P	A protein-lipid complex subunit organization process that results in the formation, disassembly, or alteration of a plasma lipoprotein particle. A plasma lipoprotein particle is a spherical particle with a hydrophobic core of triglycerides and/or cholesterol esters, surrounded by an amphipathic monolayer of phospholipids, cholesterol and apolipoproteins.
71828	apolipoprotein E recycling	P	The process in which chylomicron remnant-associated apolipoprotein E is internalized by endocytosis, localized to recycling endosomes and then secreted in association with a high-density lipoprotein particle.
71829	plasma lipoprotein particle disassembly	P	The disaggregation of a plasma lipoprotein particle into its constituent components.
71830	triglyceride-rich lipoprotein particle clearance	P	The process in which a triglyceride-rich lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.
71831	intermediate-density lipoprotein particle clearance	P	The process in which a intermediate-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.
71832	peptide pheromone export involved in conjugation	P	The directed movement of a peptide pheromone out of a cell by a secretion or export pathway used solely for the export of peptide pheromones that contributes to the union or introduction of genetic information from compatible mating types that results in a genetically different individual. Conjugation requires direct cellular contact between the organisms.
71833	peptide pheromone export involved in conjugation with cellular fusion	P	The directed movement of a peptide pheromone out of a cell by a secretion or export pathway used solely for the export of peptide pheromones that contributes to a conjugation process that results in the union of cellular and genetic information from compatible mating types.
71834	mating pheromone secretion	P	The regulated release of a mating pheromone, a peptide hormone that induces a behavioral or physiological response(s) from a responding organism or cell, that contributes to a process of sexual reproduction.
71835	mating pheromone secretion involved in conjugation	P	The regulated release of a mating pheromone, a peptide hormone that induces a behavioral or physiological response(s) from a responding organism or cell, that contributes to the union or introduction of genetic information from compatible mating types that results in a genetically different individual. Conjugation requires direct cellular contact between the organisms.
71836	nectar secretion	P	The controlled release of a nectar by a cell or a tissue. Nectar is a fluid secreted by many angiosperms to promote pollination by providing a reward to pollinators. Nectar may also deter certain organisms from visiting or play other biological roles. Nectar is a complex solution that may include the following types of compounds: sugars, amino acids, organic acids, alkaloids, flavonoids, glycosides, vitamins, phenolics, metal ions, oils, free fatty acids, and proteins.
71837	HMG box domain binding	F	Interacting selectively and non-covalently with an HMG box domain, a protein domain that consists of three helices in an irregular array. HMG-box domains are found in one or more copies in HMG-box proteins, which form a large, diverse family involved in the regulation of DNA-dependent processes such as transcription, replication, and strand repair, all of which require the bending and unwinding of chromatin.
71838	cell proliferation in bone marrow	P	The multiplication or reproduction of cells, resulting in the expansion of a cell population in the bone marrow.
71839	apoptotic process in bone marrow	P	The apoptotic process in cells in the bone marrow.
71840	cellular component organization or biogenesis	P	A process that results in the biosynthesis of constituent macromolecules, assembly, arrangement of constituent parts, or disassembly of a cellular component.
71846	actin filament debranching	P	An actin filament severing process that results in the removal of actin filament branches specifically at the branch points.
71847	TNFSF11-mediated signaling pathway	P	A series of molecular signals initiated by the binding of tumor necrosis factor ligand superfamily member 11 (TNFSF11) to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.
71848	positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling	P	Any TNFSF11-mediated signaling process that increases the rate, frequency, or extent of the ERK1 and ERK2 cascade.
71849	G1 cell cycle arrest in response to nitrogen starvation	P	The process in which the cell cycle is halted during G1 phase, as a result of deprivation of nitrogen.
71850	mitotic cell cycle arrest	P	The process in which the mitotic cell cycle is halted during one of the normal phases (G1, S, G2, M).
71851	mitotic G1 cell cycle arrest in response to nitrogen starvation	P	The process in which the mitotic cell cycle is halted during G1 phase, as a result of deprivation of nitrogen.
71852	fungal-type cell wall organization or biogenesis	P	A process that results in the biosynthesis of constituent macromolecules, assembly, arrangement of constituent parts, or disassembly of a fungal-type cell wall.
71853	fungal-type cell wall disassembly	P	A cellular process that results in the breakdown of a fungal-type cell wall.
71854	cell wall macromolecule catabolic process involved in fungal-type cell wall disassembly	P	The chemical reactions and pathways that result in the breakdown of macromolecules that form part of a cell wall, and contributes to the breakdown of the fungal-type cell wall.
71855	neuropeptide receptor binding	F	Interacting selectively and non-covalently with a neuropeptide receptor.
71857	beta-endorphin receptor binding	F	Interacting selectively and non-covalently with a beta-endorphin receptor.
71858	corazonin receptor binding	F	Interacting selectively and non-covalently with a corazonin receptor.
71859	neuropeptide F receptor binding	F	Interacting selectively and non-covalently with a neuropeptide F receptor.
71860	proctolin receptor binding	F	Interacting selectively and non-covalently with a proctolin receptor.
71861	tachykinin receptor binding	F	Interacting selectively and non-covalently with a tachykinin receptor.
71863	regulation of cell proliferation in bone marrow	P	A process that modulates the frequency, rate or extent of cell proliferation in the bone marrow.
71864	positive regulation of cell proliferation in bone marrow	P	A process that activates or increases the frequency, rate or extent of cell proliferation in the bone marrow.
71865	regulation of apoptotic process in bone marrow	P	Any process that modulates the occurrence or rate of cell death by apoptotic process in the bone marrow.
71866	negative regulation of apoptotic process in bone marrow	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the occurrence or rate of cell death by apoptotic process in the bone marrow.
71867	response to monoamine	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a monoamine stimulus. A monoamine is any of a group of molecular messengers that contain one amino group that is connected to an aromatic ring by ethylene group (-CH2-CH2-). Monoamines are derived from the aromatic amino acids phenylalanine, tyrosine, histidine and tryptophan.
71868	cellular response to monoamine stimulus	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a monoamine stimulus. A monoamine is any of a group of molecular messengers that contain one amino group that is connected to an aromatic ring by ethylene group (-CH2-CH2-). Monoamines are derived from the aromatic amino acids phenylalanine, tyrosine, histidine and tryptophan.
71869	response to catecholamine	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a catecholamine stimulus. A catecholamine is any of a group of biogenic amines that includes 4-(2-aminoethyl)pyrocatechol [4-(2-aminoethyl)benzene-1,2-diol] and derivatives formed by substitution.
71870	cellular response to catecholamine stimulus	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a catecholamine stimulus. A catecholamine is any of a group of biogenic amines that includes 4-(2-aminoethyl)pyrocatechol [4-(2-aminoethyl)benzene-1,2-diol] and derivatives formed by substitution.
71871	response to epinephrine	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an epinephrine stimulus. Epinephrine is a catecholamine that has the formula C9H13NO3; it is secreted by the adrenal medulla to act as a hormone, and released by certain neurons to act as a neurotransmitter active in the central nervous system.
71872	cellular response to epinephrine stimulus	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an epinephrine stimulus. Epinephrine is a catecholamine that has the formula C9H13NO3; it is secreted by the adrenal medulla to act as a hormone, and released by certain neurons to act as a neurotransmitter active in the central nervous system.
71873	response to norepinephrine	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a norepinephrine stimulus. Norepinephrine is a catecholamine that has the formula C8H11NO3; it acts as a hormone, and as a neurotransmitter in most of the sympathetic nervous system.
71874	cellular response to norepinephrine stimulus	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a norepinephrine stimulus. Norepinephrine is a catecholamine that has the formula C8H11NO3; it acts as a hormone, and as a neurotransmitter in most of the sympathetic nervous system.
71875	adrenergic receptor signaling pathway	P	A series of molecular signals generated as a consequence of an adrenergic receptor binding to one of its physiological ligands.
71877	regulation of adrenergic receptor signaling pathway	P	Any process that modulates the frequency, rate or extent of an adrenergic receptor signaling pathway activity. An adrenergic receptor signaling pathway is the series of molecular signals generated as a consequence of an adrenergic receptor binding to one of its physiological ligands.
71878	negative regulation of adrenergic receptor signaling pathway	P	Any process that stops, prevents, or reduces the frequency, rate or extent of adrenergic receptor protein signaling pathway activity. An adrenergic receptor signaling pathway is the series of molecular signals generated as a consequence of an adrenergic receptor binding to one of its physiological ligands.
71879	positive regulation of adrenergic receptor signaling pathway	P	Any process that activates or increases the frequency, rate or extent of the adrenergic receptor protein signaling pathway. An adrenergic receptor signaling pathway is the series of molecular signals generated as a consequence of an adrenergic receptor binding to one of its physiological ligands.
71880	adenylate cyclase-activating adrenergic receptor signaling pathway	P	The series of molecular signals generated as a consequence of an adrenergic receptor binding to its physiological ligand, where the pathway proceeds with activation of adenylyl cyclase and a subsequent increase in the concentration of cyclic AMP (cAMP).
71881	adenylate cyclase-inhibiting adrenergic receptor signaling pathway	P	The series of molecular signals generated as a consequence of an adrenergic receptor binding to its physiological ligand, where the pathway proceeds with inhibition of adenylyl cyclase and a subsequent decrease in the concentration of cyclic AMP (cAMP).
71882	phospholipase C-activating adrenergic receptor signaling pathway	P	The series of molecular signals generated as a consequence of an adrenergic receptor binding to its physiological ligand, where the pathway proceeds with activation of phospholipase C (PLC) and a subsequent release of inositol trisphosphate (IP3) and diacylglycerol (DAG).
71883	activation of MAPK activity by adrenergic receptor signaling pathway	P	The series of molecular signals generated as a consequence of an adrenergic receptor binding to its physiological ligand, followed by the activation of a MAP kinase.
71884	vitamin D receptor activator activity	F	Interacting (directly or indirectly) with vitamin D receptors such that the proportion of receptors in the active form is increased.
71885	N-terminal protein N-methyltransferase activity	F	Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine (AdoMet) to the alpha-amino group of the N-terminal amino or imino acid residue of a protein substrate. For example, yeast Tae1p and mammalian family member METTL11A preferentially modify the N-terminal residue of substrates with the N-terminal sequence X-Pro-Lys, where X can be Pro, Ala, or Ser.
71886	1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine binding	F	Interacting selectively and non-covalently with the amine 1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine, a serotonin receptor agonist that can act as a psychedelic drug.
71887	leukocyte apoptotic process	P	Any apoptotic process in a leukocyte, an achromatic cell of the myeloid or lymphoid lineages capable of ameboid movement, found in blood or other tissue.
71888	macrophage apoptotic process	P	Any apoptotic process in a macrophage, a mononuclear phagocyte present in a variety of tissues.
71889	14-3-3 protein binding	F	Interacting selectively and non-covalently with a 14-3-3 protein. A 14-3-3 protein is any of a large family of approximately 30kDa acidic proteins which exist primarily as homo- and heterodimers within all eukaryotic cells, and have been implicated in the modulation of distinct biological processes by binding to specific phosphorylated sites on diverse target proteins, thereby forcing conformational changes or influencing interactions between their targets and other molecules. Each 14-3-3 protein sequence can be roughly divided into three sections: a divergent amino terminus, the conserved core region and a divergent carboxyl terminus. The conserved middle core region of the 14-3-3s encodes an amphipathic groove that forms the main functional domain, a cradle for interacting with client proteins.
71890	bicarbonate binding	F	Interacting selectively and non-covalently with bicarbonate (CHO3-) ions.
71891	N-terminal peptidyl-proline dimethylation involved in translation	P	An N-terminal peptidyl-proline dimethylation process that contributes to translation.
71892	thrombocyte activation	P	A cell activation process that occurs in thrombocytes and consists of a series of progressive, overlapping events including shape change, adhesiveness, and aggregation, which, when carried through to completion, lead to the formation of a stable hemostatic plug. Thrombocytes are nucleated cells found in non-mammalian vertebrates and are involved in hemostasis. They are the functional equivalent of the non-nucleated platelets found in mammals.
71893	BMP signaling pathway involved in nephric duct formation	P	A series of molecular signals initiated by the binding of a member of the BMP (bone morphogenetic protein) family to a receptor on the surface of a target cell, which contributes to nephric duct formation.
71894	histone H2B conserved C-terminal lysine ubiquitination	P	A histone ubiquitination process in which a ubiquitin monomer is added to a conserved lysine residue in the C-terminus of histone H2B. The conserved lysine residue is K119 in fission yeast, K123 in budding yeast, or K120 in mammals.
71895	odontoblast differentiation	P	The process in which a relatively unspecialized cell of neural crest origin acquires the specialized features of an odontoblast, a cell on the outer surface of the dental pulp whose biological function is the creation of dentin.
71896	protein localization to adherens junction	P	Any process in which a protein is transported to, and/or maintained at the adherens junction.
71897	DNA biosynthetic process	P	The cellular DNA metabolic process resulting in the formation of DNA, deoxyribonucleic acid, one of the two main types of nucleic acid, consisting of a long unbranched macromolecule formed from one or two strands of linked deoxyribonucleotides, the 3'-phosphate group of each constituent deoxyribonucleotide being joined in 3',5'-phosphodiester linkage to the 5'-hydroxyl group of the deoxyribose moiety of the next one.
71898	regulation of estrogen receptor binding	P	Any process that modulates the frequency, rate or extent of estrogen receptor binding, interacting selectively with a an estrogen receptor.
71899	negative regulation of estrogen receptor binding	P	Any process that stops, prevents, or reduces the frequency, rate or extent of estrogen receptor binding, interacting selectively with an estrogen receptor.
71900	regulation of protein serine/threonine kinase activity	P	Any process that modulates the rate, frequency, or extent of protein serine/threonine kinase activity.
71901	negative regulation of protein serine/threonine kinase activity	P	Any process that decreases the rate, frequency, or extent of protein serine/threonine kinase activity.
71902	positive regulation of protein serine/threonine kinase activity	P	Any process that increases the rate, frequency, or extent of protein serine/threonine kinase activity.
71903	protein N-linked N-acetylglucosaminylation via asparagine	P	A process of protein N-linked glycosylation via asparagine in which N-acetylglucosamine is added to the N4 of asparagine, forming an (S)-2-amino-4-(2-acetamido-2-deoxy-beta-D-glucopyranosyl)amino-4-oxobutanoic acid residue.
71904	protein N-linked N-acetylgalactosaminylation via asparagine	P	A process of protein N-linked glycosylation via asparagine in which N-acetylgalactosamine is added to the N4 of asparagine, forming an (S)-2-amino-4-(2-acetamido-2-deoxy-beta-D-galactopyranosyl)amino-4-oxobutanoic acid residue.
71905	protein N-linked glucosylation via asparagine	P	A process of protein N-linked glycosylation via asparagine in which glucose is added to the N4 of asparagine, forming an (S)-2-amino-4-(D-glucopyranosyl)amino-4-oxobutanoic acid residue.
71906	CRD domain binding	F	Interacting selectively and non-covalently with a CRD (context dependent regulatory) domain, a domain of about 130 residues that is the most divergent region among the LEF/TCF proteins.
71907	determination of digestive tract left/right asymmetry	P	Determination of the asymmetric location of various parts of the digestive tract with respect to the left and right halves of the organism. The digestive tract is the anatomical structure through which food passes and is processed.
71908	determination of intestine left/right asymmetry	P	Determination of the asymmetric location of the intestine loops with respect to the left and right halves of the organism.
71909	determination of stomach left/right asymmetry	P	Determination of the asymmetric location of the stomach with respect to the left and right halves of the organism.
71910	determination of liver left/right asymmetry	P	Determination of the asymmetric location of the liver with respect to the left and right halves of the organism.
71911	synchronous neurotransmitter secretion	P	Release of neurotransmitter at the synapse that lasts for just a few milliseconds after action potential invasion.
71912	asynchronous neurotransmitter secretion	P	Release of neurotransmitter at the synapse that persists for tens to hundreds of milliseconds after action potential invasion.
71913	citrate secondary active transmembrane transporter activity	F	Catalysis of the transfer of citrate from one side of a membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Chemiosmotic sources of energy include uniport, symport or antiport.
71914	prominosome	C	An extracellular membrane-bounded vesicle that contains prominin proteins (in mouse Prom1/CD33 or Prom2) and are found in body fluids including ventricular fluid, saliva, urine and seminal fluid. In the ventricular fluid of the developing mouse brain two major classes of these particles have been observed (P2 particles of 500-1000 nm and P4 particles of 50-80 nm) which likely originate from microvilli, primary cilia and/or the midbody of neuroepithelial cells. The physiological role is not known.
71915	protein-lysine lysylation	P	The addition of lysine group to a lysine residue in a protein, producing N6-(lysyl)-L-lysine. This modification is observed in, and is probably unique to, translation elongation factor P (EF-P).
71916	dipeptide transmembrane transporter activity	F	Enables the directed movement of a dipeptide across a membrane into, out of or within a cell, or between cells. A dipeptide is a combination of two amino acids linked together by a peptide (-CO-NH-) bond.
71917	triose-phosphate transmembrane transporter activity	F	Catalysis of the transfer of a triose phosphate from one side of a membrane to the other.
71918	urea transmembrane transport	P	The process in which urea, the water-soluble compound H2N-CO-NH2, is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.
71919	G-quadruplex DNA formation	P	A DNA metabolic process that results in the formation of G-quadruplex DNA structures, in which groups of four guanines adopt a flat, cyclic Hoogsteen hydrogen-bonding arrangement known as a guanine tetrad or G-quartet. The stacking of several layers of G-quartets forms G-quadruplexes, in which one or more DNA single strands are assembled in parallel and/or antiparallel, with interactions that can be either intra- or intermolecular in nature.
71920	cleavage body	C	A nuclear body that contains proteins involved in pre-mRNA 3'-end cleavage and polyadenylation, such as DDX1, CSTF2 and CPSFs, as well as the transcription factors TFIIE and TFIIF. Cleavage bodies are localized adjacent to Cajal bodies and are involved in mRNA3'-end processing.
71921	cohesin loading	P	The protein localization to chromatin by which a cohesin ring complex is topologically linked to DNA.
71922	regulation of cohesin loading	P	Any process that modulates the frequency, rate or extent of a process in which a cohesin complex is transported to, or maintained at, a part of a chromosome that is organized into chromatin.
71923	negative regulation of cohesin loading	P	Any process that stops, prevents, or reduces the frequency, rate or extent of a process in which a cohesin complex is transported to, or maintained at, a part of a chromosome that is organized into chromatin.
71924	chemokine (C-C motif) ligand 22 production	P	The appearance of chemokine (C-C motif) ligand 22 (CCL22) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
71925	thymic stromal lymphopoietin production	P	The appearance of thymic stromal lymphopoietin (TSLP) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
71926	endocannabinoid signaling pathway	P	The series of molecular signals generated as a consequence of an endocannabinoid binding to a cell surface receptor. The pathway proceeds with the receptor transmitting the signal to a heterotrimeric G-protein complex and ends with regulation of a downstream cellular process, e.g. transcription. Endocannabinoids are small molecules derived from arachidonic acid, anandamide (arachidonoylethanolamide) and 2-arachidonoylglycerol.
71927	octopamine signaling pathway	P	The series of molecular signals generated as a consequence of octopamine binding to a cell surface receptor.
71928	tyramine signaling pathway	P	The series of molecular signals generated as a consequence of tyramine binding to a cell surface receptor.
71929	alpha-tubulin acetylation	P	The addition of an acetyl group to the lysine 40 residue of alpha-tubulin.
71930	negative regulation of transcription involved in G1/S transition of mitotic cell cycle	P	Any process that stop, prevents or decreases transcription as part of the G1/S transition of the mitotic cell cycle.
71931	positive regulation of transcription involved in G1/S transition of mitotic cell cycle	P	Any process that activates or increases transcription as part of the G1/S transition of the mitotic cell cycle.
71932	replication fork reversal	P	Replication fork processing that involves the unwinding of blocked forks to form four-stranded structures resembling Holliday junctions, which are subsequently resolved.
71933	Arp2/3 complex binding	F	Interacting selectively and non-covalently with an Arp2/3 complex, a protein complex that contains two actin-related proteins, Arp2 and Arp3, and five novel proteins (ARPC1-5).
71934	thiamine transmembrane transport	P	The directed movement of thiamine across a membrane into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Thiamine is vitamin B1, a water soluble vitamin present in fresh vegetables and meats, especially liver.
71935	octopamine signaling pathway involved in response to food	P	The series of molecular signals initiated by binding of octopamine to a receptor on the surface of the target cell that contributes to a response to a food stimulus.
71936	coreceptor activity involved in Wnt signaling pathway	F	In cooperation with a primary Wnt receptor, initiating a change in cell activity through the Wnt signaling pathway.
71938	vitamin A transport	P	The directed movement any form of vitamin A into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Vitamin A is any of several retinoid derivatives of beta-carotene, primarily retinol, retinal, or retinoic acid.
71939	vitamin A import	P	The directed movement of vitamin A into a cell or organelle. Vitamin A is any of several retinoid derivatives of beta-carotene, primarily retinol, retinal, or retinoic acid.
71940	fungal-type cell wall assembly	P	The aggregation, arrangement and bonding together of a set of components to form a fungal-type cell wall.
71941	nitrogen cycle metabolic process	P	A nitrogen compound metabolic process that contributes to the nitrogen cycle. The nitrogen cycle is a series of metabolic pathways by which nitrogen is converted between various forms and redox states; it encompasses pathways in which nitrogen is acted upon directly, such as nitrification, denitrification, nitrogen fixation, and mineralization.
71942	XPC complex	C	A nucleotide-excision repair complex that is involved in damage sensing during global genome nucleotide excision repair (GG-NER). It is part of the pre-incision (or initial recognition) complex bound to sites of DNA damage. In human, it is composed of XPC, RAD23B and CETN2.
71943	Myc-Max complex	C	A transcription factor complex that consists of a heterodimer of the bHLH-ZIP proteins Myc and Max.
71944	cell periphery	C	The part of a cell encompassing the cell cortex, the plasma membrane, and any external encapsulating structures.
71945	regulation of bacterial-type flagellum-dependent cell motility by regulation of motor speed	P	A process that modulates flagellum-dependent motility in bacteria by modulating the speed or direction of rotation of a rotary flagellar motor, mediated by interactions between the braking protein.
71946	cis-acting DNA replication termination	P	A DNA replication termination process that is initiated by protein binding to a binding site on the same chromosome, but remote from the termination site, via DNA looping or chromosome kissing.
71947	protein deubiquitination involved in ubiquitin-dependent protein catabolic process	P	The removal of one or more ubiquitin groups from a protein as part of a process of ubiquitin-dependent protein catabolism.
71948	activation-induced B cell apoptotic process	P	B cell apoptotic process that occurs upon engagement of either the B cell receptor or CD40. Engagement of either receptor, but not both, leads to expression of fas or related receptors that make the B cell susceptible to fas-ligand mediated death.
71949	FAD binding	F	Interacting selectively and non-covalently with the oxidized form, FAD, of flavin-adenine dinucleotide, the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes.
71950	FADH2 binding	F	Interacting selectively and non-covalently with the reduced form, FADH2, of flavin-adenine dinucleotide, the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes.
71951	conversion of methionyl-tRNA to N-formyl-methionyl-tRNA	P	The modification process that results in the conversion of methionine charged on a tRNA(fMet) to N-formyl-methionine-tRNA(fMet).
71952	conversion of O-phosphoseryl-tRNA to cysteinyl-tRNA	P	The modification process that results in the conversion of O-phosphoserine charged on a tRNA(Cys) to cysteinyl-tRNA.
71953	elastic fiber	C	An extracellular matrix part that consists of an insoluble core of polymerized tropoelastin monomers and a surrounding mantle of microfibrils. Elastic fibers provide elasticity and recoiling to tissues and organs, and maintain structural integrity against mechanical strain.
71954	chemokine (C-C motif) ligand 11 production	P	The appearance of chemokine (C-C motif) ligand 11 (CCL11, also known as eotaxin-1) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
71955	recycling endosome to Golgi transport	P	The directed movement of substances from recycling endosomes to the Golgi.
71957	old mitotic spindle pole body	C	The spindle pole body that exists in a cell prior to spindle pole body duplication. An old spindle pole body segregates to the daughter cell upon mitosis, and lacks active proteins involved in signaling exit from mitosis.
71958	new mitotic spindle pole body	C	The spindle pole body that is formed by spindle pole body duplication, and to which proteins involved in mitotic exit signaling (for example, the septation initiation network in fission yeast) localize.
71959	maintenance of mitotic sister chromatid cohesion, arms	P	The process in which the association between sister chromatids of a replicated chromosome along the length of the chromosome arms, is maintained as chromosomes condense, attach to the spindle in a bipolar orientation, and congress to the metaphase plate during a mitotic cell cycle.
71960	maintenance of mitotic sister chromatid cohesion, centromeric	P	The process in which the association between sister chromatids of a replicated chromosome along the length of the centromeric region is maintained as chromosomes condense, attach to the spindle in a bipolar orientation, and congress to the metaphase plate during a mitotic cell cycle.
71961	mitotic sister chromatid cohesion, arms	P	The cell cycle process in which the sister chromatids of a replicated chromosome are joined along the length of the chromosome arms during mitosis.
71962	mitotic sister chromatid cohesion, centromeric	P	The cell cycle process in which centromeres of sister chromatids are joined during mitosis.
71963	establishment or maintenance of cell polarity regulating cell shape	P	Any cellular process that results in the specification, formation or maintenance of a polarized intracellular organization or cell growth patterns that regulate the shape of a cell.
71964	establishment of cell polarity regulating cell shape	P	Any cellular process that results in the specification or formation of a polarized intracellular organization or cell growth pattern that regulates the shape of a cell.
71965	multicellular organismal locomotion	P	Locomotion in a multicellular organism, i.e. self-propelled movement of a multicellular organism from one location to another.
71966	fungal-type cell wall polysaccharide metabolic process	P	The chemical reactions and pathways involving the polysaccharides which make up the fungal-type cell wall.
71967	lipopolysaccharide core heptosyltransferase activity	F	Catalysis of the reaction: glucosyl-heptosyl2-KDO2-lipid A-phosphate + ADP-L-glycero-beta-D-manno-heptose = glucosyl-heptosyl3-KDO2-lipid A-phosphate + ADP + H+.
71968	lipid A-core heptosyltransferase activity	F	Catalysis of the reaction: galactosyl-glucosyl3-heptosyl3-KDO2-lipid A-bisphosphate + ADP-L-glycero-beta-D-manno-heptose = lipid A-core + ADP + H+.
71969	fungal-type cell wall (1->3)-beta-D-glucan metabolic process	P	The chemical reactions and pathways involving (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D-glucosidic bonds, found in the walls of fungi.
71970	fungal-type cell wall (1->3)-beta-D-glucan biosynthetic process	P	The chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D-glucosidic bonds, found in fungal cell walls.
71971	extracellular exosome assembly	P	The aggregation, arrangement and bonding together of a set of components to form an extracellular vesicular exosome, a membrane-bounded vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane.
71972	peptidoglycan L,D-transpeptidase activity	F	Catalysis of the reaction: 2 a peptidoglycan dimer (tetrapeptide) + 3 H2O = a peptidoglycan tetramer with L,D cross-links (L-Lys-D-Asn-L-Lys) + di-trans,poly-cis-undecaprenyl diphosphate + 4 D-alanine.
71973	bacterial-type flagellum-dependent cell motility	P	Cell motility due to the motion of one or more bacterial-type flagella. A bacterial-type flagellum is a motor complex composed of an extracellular helical protein filament coupled to a rotary motor embedded in the cell envelope.
71975	cell swimming	P	Cell motility that results in the smooth movement of a cell through a liquid medium.
71976	cell gliding	P	Cell motility that results in the smooth movement of a cell along a solid surface.
71977	bacterial-type flagellum-dependent swimming motility	P	Bacterial-type flagellum-dependent cell motility that results in the smooth movement of a cell through a liquid medium.
71978	bacterial-type flagellum-dependent swarming motility	P	Bacterial-type flagellum-dependent cell motility in which the action of numerous flagella results in the smooth movement of a group of cells along a solid surface. Swarming motility is observed in groups of bacteria.
71979	cytoskeleton-mediated cell swimming	P	Cell motility in which contractile cytoskeletal elements alter cell shape, resulting in the smooth movement of a cell through a liquid medium.
71980	cell surface adhesin-mediated gliding motility	P	Cell gliding that results from the actions of cell surface adhesin proteins that are propelled by membrane motor proteins.
71981	exit from diapause	P	The dormancy process that results in exit from diapause. Diapause is a neurohormonally mediated, dynamic state of low metabolic activity. Associated characteristics of this form of dormancy include reduced morphogenesis, increased resistance to environmental extremes, and altered or reduced behavioral activity. Full expression develops in a species-specific manner, usually in response to a number of environmental stimuli that precede unfavorable conditions. Once diapause has begun, metabolic activity is suppressed even if conditions favorable for development prevail. Once initiated, only certain stimuli are capable of releasing the organism from this state, and this characteristic is essential in distinguishing diapause from hibernation.
71982	maintenance of diapause	P	The dormancy process that results an organism remaining in diapause. Diapause is a neurohormonally mediated, dynamic state of low metabolic activity. Associated characteristics of this form of dormancy include reduced morphogenesis, increased resistance to environmental extremes, and altered or reduced behavioral activity. Full expression develops in a species-specific manner, usually in response to a number of environmental stimuli that precede unfavorable conditions. Once diapause has begun, metabolic activity is suppressed even if conditions favorable for development prevail. Once initiated, only certain stimuli are capable of releasing the organism from this state, and this characteristic is essential in distinguishing diapause from hibernation.
71983	exit from reproductive diapause	P	The dormancy process that results in exit from reproductive diapause. Reproductive diapause is a form of diapause where the organism itself will remain fully active, including feeding and other routine activities, but the reproductive organs experience a tissue-specific reduction in metabolism, with characteristic triggering and releasing stimuli.
71984	maintenance of reproductive diapause	P	The dormancy process that results an organism remaining in reproductive diapause. Reproductive diapause is a form of diapause where the organism itself will remain fully active, including feeding and other routine activities, but the reproductive organs experience a tissue-specific reduction in metabolism, with characteristic triggering and releasing stimuli.
71985	multivesicular body sorting pathway	P	A vesicle-mediated transport process in which transmembrane proteins are ubiquitylated to facilitate their entry into luminal vesicles of multivesicular bodies (MVBs); upon subsequent fusion of MVBs with lysosomes or vacuoles, the cargo proteins are degraded.
71986	Ragulator complex	C	A protein complex that contains MAPKSP1 (MP1, Map2k1ip1), ROBLD3 (p14, Mapbpip), C11orf59 (p18), LAMTOR4 and LAMTOR5. The complex is anchored to lipid rafts in late endosome membranes via C11orf59, recruits mTORC1 to lysosomal membranes in amino acid signaling to mTORC1, constitutes a guanine nucleotide exchange factor (GEF) for the Rag GTPases, and is also involved in ERK/MAPK signaling.
71987	WD40-repeat domain binding	F	Interacting selectively and non-covalently with a WD40 repeat domain of a protein. The WD40 repeat is a short structural motif of approximately 40 amino acids, often terminating in a tryptophan-aspartic acid (W-D) dipeptide. Several of these repeats are combined to form a type of protein domain called the WD domain.
71988	protein localization to spindle pole body	P	A process in which a protein is transported to, or maintained at, the spindle pole body.
71989	establishment of protein localization to spindle pole body	P	The directed movement of a protein to a specific location at the spindle pole body.
71990	maintenance of protein location to spindle pole body	P	Any process in which a protein is maintained in a specific location at the spindle pole body, and is prevented from moving elsewhere.
71991	phytochelatin transporter activity	F	Enables the directed movement of a phytochelatin into, out of or within a cell, or between cells. Phytochelatins are a group of peptides that bind metals (Cd, Zn, Cu, Pb, Hg) in thiolate coordination complexes.
71992	phytochelatin transmembrane transporter activity	F	Enables the directed movement of a phytochelatin across a membrane into, out of or within a cell, or between cells. Phytochelatins are a group of peptides that bind metals (Cd, Zn, Cu, Pb, Hg) in thiolate coordination complexes.
71993	phytochelatin transport	P	The directed movement of a phytochelatin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Phytochelatins are a group of peptides that bind metals (Cd, Zn, Cu, Pb, Hg) in thiolate coordination complexes.
71994	phytochelatin transmembrane transport	P	The directed movement of a phytochelatin across a membrane into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Phytochelatins are a group of peptides that bind metals (Cd, Zn, Cu, Pb, Hg) in thiolate coordination complexes.
71995	phytochelatin import into vacuole	P	The directed movement of phytochelatins into the vacuole. Phytochelatins are a group of peptides that bind metals (Cd, Zn, Cu, Pb, Hg) in thiolate coordination complexes.
71996	glutathione transmembrane import into vacuole	P	The directed movement of glutathione into the vacuole across the vacuolar membrane.
71997	glutathione S-conjugate-transporting ATPase activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O = ADP + phosphate, to directly drive the transport of glutathione S-conjugate across a membrane.
71998	ascospore release from ascus	P	A developmental process that results in the discharge of ascospores from the ascus. Ascospore release may be active or passive.
71999	extracellular polysaccharide catabolic process	P	The chemical reactions and pathways resulting in the breakdown of polysaccharides used in extracellular structures.
72000	extracellular polysaccharide catabolic process involved in ascospore release from ascus	P	The chemical reactions and pathways resulting in the breakdown of polysaccharides in the ascus wall that contributes to the release of ascospores from the ascus.
72001	renal system development	P	The process whose specific outcome is the progression of the renal system over time, from its formation to the mature structure. The renal system maintains fluid balance and contributes to electrolyte balance, acid/base balance, and disposal of nitrogenous waste products. In humans, the renal system comprises a pair of kidneys, a pair of ureters, urinary bladder, urethra, sphincter muscle and associated blood vessels.
72002	Malpighian tubule development	P	The process whose specific outcome is the progression of the Malpighian tubule over time, from its formation to the mature structure. A Malpighian tubule is a fine, thin-walled excretory tubule in insects which leads into the posterior part of the gut.
72003	kidney rudiment formation	P	The developmental process pertaining to the initial formation of a kidney rudiment from unspecified parts. A kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine.
72004	kidney field specification	P	The process that results in the delineation of regions of the embryo into the area in which the kidney rudiment will develop.
72005	maintenance of kidney identity	P	The process in which the identity of a kidney is maintained. Identity is considered to be the aggregate of characteristics by which a structure is recognized.
72006	nephron development	P	The process whose specific outcome is the progression of the nephron over time, from its formation to the mature structure. A nephron is the functional unit of the kidney.
72007	mesangial cell differentiation	P	The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesangial cells of the kidney as it progresses from its formation to the mature state.
72008	glomerular mesangial cell differentiation	P	The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the glomerular mesangial cells of the kidney as it progresses from its formation to the mature state.
72009	nephron epithelium development	P	The process whose specific outcome is the progression of the nephron epithelium over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. The nephron epithelium is a tissue that covers the surface of a nephron.
72010	glomerular epithelium development	P	The process whose specific outcome is the progression of the glomerular epithelium over time, from its formation to the mature structure. The glomerular epithelium is an epithelial tissue that covers the outer surfaces of the glomerulus. The glomerular epithelium consists of both parietal and visceral epithelium. Metanephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport. A metanephric glomerular visceral epithelial cell is a specialized epithelial cell that contains "feet" that interdigitate with the "feet" of other glomerular epithelial cells in the metanephros.
72011	glomerular endothelium development	P	The process whose specific outcome is the progression of the glomerular endothelium over time, from its formation to the mature structure. The glomerular endothelium is an epithelial tissue that covers the internal surfaces of the glomerulus.
72012	glomerulus vasculature development	P	The biological process whose specific outcome is the progression of a glomerulus vasculature from an initial condition to its mature state. This process begins with the formation of the glomerulus vasculature and ends with the mature structure. The glomerulus vasculature is composed of the tubule structures that carry blood or lymph in the glomerulus.
72013	glomus development	P	The progression of the glomus over time from its initial formation until its mature state. The glomus forms from the splanchnic intermediate mesoderm and is the vascularized filtration unit, filtering the blood before it enters the tubules. The glomus is external to the nephron and extends over more than one body segment.
72014	proximal tubule development	P	The process whose specific outcome is the progression of the proximal tubule over time, from its formation to the mature structure. In mammals, the proximal tubule is a nephron tubule that connects Bowman's capsule to the descending thin limb of the loop of Henle. It has a brush border epithelial morphology.
72015	glomerular visceral epithelial cell development	P	The process whose specific outcome is the progression of a glomerular visceral epithelial cell over time, from its formation to the mature structure. A glomerular visceral epithelial cell is a specialized epithelial cell that contains "feet" that interdigitate with the "feet" of other glomerular epithelial cells.
72016	glomerular parietal epithelial cell development	P	The process whose specific outcome is the progression of a glomerular parietal epithelial cell over time, from its formation to the mature structure. Glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport.
72017	distal tubule development	P	The process whose specific outcome is the progression of the distal tubule over time, from its formation to the mature structure. In mammals, the distal tubule is a nephron tubule that begins at the macula densa and extends to the connecting tubule.
72019	proximal convoluted tubule development	P	The process whose specific outcome is the progression of the proximal convoluted tubule over time, from its formation to the mature structure. The proximal convoluted tubule is the most proximal portion of the proximal tubule and extends from the glomerular capsule to the proximal straight tubule.
72020	proximal straight tubule development	P	The process whose specific outcome is the progression of the proximal straight tubule over time, from its formation to the mature structure. The proximal straight tubule is the part of the descending limb that extends from the proximal convoluted tubule to the descending thin tubule.
72021	ascending thin limb development	P	The process whose specific outcome is the progression of an ascending thin limb over time, from its formation to the mature structure. The ascending thin limb is a segment of a nephron tubule lying in the inner medulla that is permeable to ions but not to water and has a simple epithelium; active transepithelial solute transport is absent.
72022	descending thin limb development	P	The process whose specific outcome is the progression of the descending thin limb over time, from its formation to the mature structure. The descending thin limb is a part of the loop of Henle situated just after the proximal straight tubule (S3). It extends to the tip of the loop of Henle.
72023	thick ascending limb development	P	The process whose specific outcome is the progression of the thick ascending limb over time, from its formation to the mature structure. The thick ascending limb is the last part of the loop of Henle. Its thick, mitochondria-rich epithelium characterizes the outer medulla, and is responsible for very avid active salt transport. At the macula densa, the thick ascending limb connects to the distal convoluted tubule.
72024	macula densa development	P	The process whose specific outcome is the progression of the macula densa over time, from its formation to the mature structure. The macula densa is an area of specialized cells in the distal tubule that makes contact with the vascular pole of the glomerulus.
72025	distal convoluted tubule development	P	The process whose specific outcome is the progression of the distal convoluted tubule over time, from its formation to the mature structure. The distal convoluted tubule is the first segment of the nephron lying just downstream from the loop of Henle, immediately after the macula densa. Among other functions, in humans it is responsible for the reabsorption of about 5% of filtered sodium via the thiazide-sensitive Na-Cl symporter.
72027	connecting tubule development	P	The process whose specific outcome is the progression of the connecting tubule over time, from its formation to the mature structure. The connecting tubule is a tubular segment of the nephron; it connects the distal convoluted tubule to the collecting duct.
72028	nephron morphogenesis	P	The process in which the anatomical structures of the nephron are generated and organized. A nephron is the functional unit of the kidney.
72029	long nephron development	P	The process whose specific outcome is the progression of a long nephron over time, from its formation to the mature structure. Long nephrons are associated with juxtamedullary glomeruli and extend into the inner medulla.
72030	short nephron development	P	The process whose specific outcome is the progression of a short nephron over time, from its formation to the mature structure. Short nephrons are associated with mid-cortical and superficial glomeruli, are situated entirely in the outer medulla, and have no thin ascending limb.
72031	proximal convoluted tubule segment 1 development	P	The process whose specific outcome is the progression of the S1 portion of the proximal convoluted tubule over time, from its formation to the mature structure. The S1 portion is the initial portion of the proximal convoluted tubule and is responsible for avid reabsorption of water and solutes.
72032	proximal convoluted tubule segment 2 development	P	The process whose specific outcome is the progression of the S2 portion of the proximal convoluted tubule over time, from its formation to the mature structure. The S2 portion of the tubule is involved in reabsorption of water and sodium chloride.
72033	renal vesicle formation	P	The developmental process pertaining to the initial formation of the renal vesicle from condensed mesenchymal cells. The renal vesicle is the primordial structure of the nephron epithelium, and is formed by the condensation of mesenchymal cells.
72034	renal vesicle induction	P	Signaling at short range between cells of the ureteric bud terminus and the kidney mesenchyme that positively regulates the formation of the renal vesicle.
72035	pre-tubular aggregate formation	P	The cell adhesion process in which mesenchyme cells adhere to one another in the initial stages of the formation of the pre-tubular aggregate, the earliest recognizable structure of the kidney.
72036	mesenchymal to epithelial transition involved in renal vesicle formation	P	A transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the renal vesicle.
72037	mesenchymal stem cell differentiation involved in nephron morphogenesis	P	The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal stem cell that contributes to the shaping of a nephron. A mesenchymal stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells.
72038	mesenchymal stem cell maintenance involved in nephron morphogenesis	P	The process in which an organism retains a population of mesenchymal stem cells that contributes to the shaping of a nephron. A mesenchymal stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells.
72039	regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis	P	Any process that modulates the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron.
72040	negative regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis	P	Any process that reduces the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron.
72041	positive regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis	P	Any process that increases the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron.
72042	regulation of mesenchymal stem cell proliferation involved in nephron morphogenesis	P	Any process that modulates the frequency, rate or extent of mesenchymal stem cell proliferation and contributes to the shaping of a nephron.
72043	regulation of pre-tubular aggregate formation by cell-cell signaling	P	Any process that mediates the transfer of information from one cell to another that modulates the rate, frequency, or extent of pre-tubular aggregate formation. Pre-tubular aggregate formation is the cell adhesion process in which mesenchymal cells adhere to one another in the initial stages of the formation of the pre-tubular aggregate, the earliest recognizable structure of the kidney.
72044	collecting duct development	P	The process whose specific outcome is the progression of a collecting duct over time, from its formation to the mature structure. The collecting duct responds to vasopressin and aldosterone to regulate water, electrolyte and acid-base balance. It is the final common path through which urine flows before entering the ureter and then emptying into the bladder.
72045	convergent extension involved in nephron morphogenesis	P	The morphogenetic process in which the renal epithelium narrows along one axis and lengthens in a perpendicular axis that contributes to the shaping of a nephron.
72046	establishment of planar polarity involved in nephron morphogenesis	P	Coordinated organization of groups of cells in the plane of an epithelium that contributes to the shaping of a nephron.
72047	proximal/distal pattern formation involved in nephron development	P	The regionalization process in which specific areas of cell differentiation are determined along a proximal/distal axis of a nephron. The proximal/distal axis is defined by a line that runs from the center of the kidney (proximal end) outward (distal end).
72048	renal system pattern specification	P	Any developmental process that results in the creation of defined areas or spaces within an organism to which cells respond and eventually are instructed to differentiate into the anatomical structures of the renal system.
72049	comma-shaped body morphogenesis	P	The process in which the comma-shaped body is generated and organized. The comma-shaped body is the precursor structure to the S-shaped body that contributes to the morphogenesis of the nephron.
72050	S-shaped body morphogenesis	P	The process in which the S-shaped body is generated and organized. The S-shaped body is the successor of the comma-shaped body that contributes to the morphogenesis of the nephron.
72051	juxtaglomerular apparatus development	P	The process whose specific outcome is the progression of the juxtaglomerular apparatus over time, from its formation to the mature structure. The juxtaglomerular apparatus is an anatomical structure that lies adjacent to the glomerulus and regulates kidney function.
72052	juxtaglomerulus cell differentiation	P	The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the juxtaglomerulus cells of the kidney as it progresses from its formation to the mature state.
72053	renal inner medulla development	P	The process whose specific outcome is the progression of the renal inner medulla over time, from its formation to the mature structure. The renal inner medulla is unique to mammalian kidneys and is the innermost region of the mammalian kidney.
72054	renal outer medulla development	P	The process whose specific outcome is the progression of the renal outer medulla over time, from its formation to the mature structure. The renal outer medulla is the region of the kidney that lies between the renal cortex and the renal inner medulla.
72055	renal cortex development	P	The process whose specific outcome is the progression of the renal cortex over time, from its formation to the mature structure. The renal cortex is the outer region of the kidney.
72056	pyramid development	P	The process whose specific outcome is the progression of the kidney pyramids over time, from its formation to the mature structure. Kidney pyramids are the conical masses that constitute the renal medulla in a multi-lobed mammalian kidney; they contain the loops of Henle and the medullary collecting ducts.
72057	inner stripe development	P	The process whose specific outcome is the progression of the inner stripe over time, from its formation to the mature structure. The inner stripe is a deep, centrally located portion of the renal outer medulla and is traversed by thin descending and thick ascending portions of the loops of Henle.
72058	outer stripe development	P	The process whose specific outcome is the progression of the outer stripe over time, from its formation to the mature structure. The outer stripe is the region of the kidney outer medulla that lies just below the cortex. The proximal straight tubules (S3) characterize this region.
72059	cortical collecting duct development	P	The process whose specific outcome is the progression of the cortical collecting duct over time, from its formation to the mature structure. The cortical collecting duct is the portion of the collecting duct that resides in the renal cortex.
72060	outer medullary collecting duct development	P	The process whose specific outcome is the progression of the outer medullary collecting duct over time, from its formation to the mature structure. The outer medullary collecting duct is the portion of the collecting duct that lies in the renal outer medulla.
72061	inner medullary collecting duct development	P	The process whose specific outcome is the progression of the inner medullary collecting duct over time, from its formation to the mature structure. The inner medullary collecting duct is the portion of the collecting duct that lies in the renal inner medulla.
72062	proximal convoluted tubule segment 1 cell differentiation	P	The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the S1 cells of the kidney as it progresses from its formation to the mature state.
72063	short descending thin limb development	P	The process whose specific outcome is the progression of the short descending thin limb over time, from its formation to the mature structure. The short descending thin limb is the descending thin limb of a short nephron that has a squamous epithelial morphology.
72064	long descending thin limb development	P	The process whose specific outcome is the progression of the long descending thin limb over time, from its formation to the mature structure. The long descending thin limb is the descending thin limb of a long nephron that has a squamous epithelial morphology. The long descending limb starts in the inner stripe of the outer medulla and extends into the inner medulla.
72065	long descending thin limb bend development	P	The process whose specific outcome is the progression of the long descending thin limb bend over time, from its formation to the mature structure. The long descending thin limb bend is a part of the descending thin limb of a long nephron that lies beyond the prebend segment.
72066	prebend segment development	P	The process whose specific outcome is the progression of the prebend segment over time, from its formation to the mature structure. The prebend segment is a part of the descending thin limb that lies before the bend and exhibits permeabilities characteristic of the ascending limb, especially negligible water permeability.
72067	early distal convoluted tubule development	P	The process whose specific outcome is the progression of the early distal convoluted tubule over time, from its formation to the mature structure. The early distal convoluted tubule contains DCT cells and is vasopressin-insensitive.
72068	late distal convoluted tubule development	P	The process whose specific outcome is the progression of the late distal convoluted tubule over time, from its formation to the mature structure. The late distal convoluted tubule contains DCT cells and intercalated (IC) alpha and beta cells and is vasopressin-sensitive.
72069	DCT cell differentiation	P	The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the distal convoluted tubule cells of the kidney as it progresses from its formation to the mature state.
72070	loop of Henle development	P	The process whose specific outcome is the progression of the loop of Henle over time, from its formation to the mature structure. The loop of Henle is a nephron tubule that connects the proximal convoluted tubule to the distal convoluted tubule.
72071	kidney interstitial fibroblast differentiation	P	The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the interstitial fibroblast of the kidney as it progresses from its formation to the mature state.
72072	kidney stroma development	P	The process whose specific outcome is the progression of the kidney stroma over time, from its formation to the mature structure. The kidney stroma is the mesenchyme of the mature kidney.
72073	kidney epithelium development	P	The process whose specific outcome is the progression of an epithelium in the kidney over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure.
72074	kidney mesenchyme development	P	The biological process whose specific outcome is the progression of a kidney mesenchyme from an initial condition to its mature state. This process begins with the formation of kidney mesenchyme and ends with the mature structure. Kidney mesenchyme is the tissue made up of loosely connected mesenchymal cells in the kidney.
72075	metanephric mesenchyme development	P	The biological process whose specific outcome is the progression of a metanephric mesenchyme from an initial condition to its mature state. This process begins with the formation of metanephric mesenchyme and ends with the mature structure. Metanephric mesenchyme is the tissue made up of loosely connected mesenchymal cells in the metanephros.
72076	nephrogenic mesenchyme development	P	The biological process whose specific outcome is the progression of a nephrogenic mesenchyme from an initial condition to its mature state. This process begins with the formation of nephrogenic mesenchyme and ends with the mature structure. Nephrogenic mesenchyme is the tissue made up of loosely connected mesenchymal cells in the nephron.
72077	renal vesicle morphogenesis	P	The process in which the anatomical structures of the renal vesicle are generated and organized. The renal vesicle is the primordial structure of the nephron epithelium, and is formed by the condensation of mesenchymal cells.
72078	nephron tubule morphogenesis	P	The process in which the anatomical structures of a nephron tubule are generated and organized. A nephron tubule is an epithelial tube that is part of the nephron, the functional part of the kidney.
72079	nephron tubule formation	P	The developmental process pertaining to the initial formation of a nephron tubule from unspecified parts. A nephron tubule is an epithelial tube that is part of the nephron, the functional part of the kidney.
72080	nephron tubule development	P	The progression of a nephron tubule over time, from its initial formation to the mature structure. A nephron tubule is an epithelial tube that is part of the nephron, the functional part of the kidney.
72081	specification of nephron tubule identity	P	The process in which the tubules arranged along the proximal/distal axis of the nephron acquire their identity.
72082	specification of proximal tubule identity	P	The process in which the proximal tubule of the kidney nephron acquires its identity.
72084	specification of distal tubule identity	P	The process in which the distal tubule of the kidney nephron acquires its identity.
72085	specification of connecting tubule identity	P	The process in which the connecting tubule of the kidney nephron acquires its identity.
72086	specification of loop of Henle identity	P	The process in which the loop of Henle of the kidney nephron acquires its identity.
72087	renal vesicle development	P	The process whose specific outcome is the progression of the renal vesicle over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. The renal vesicle is the primordial structure of the nephron epithelium, and is formed by the condensation of mesenchymal cells.
72088	nephron epithelium morphogenesis	P	The process in which the anatomical structures of the nephron epithelium are generated and organized. The nephron epithelium is a tissue that covers the surface of a nephron.
72089	stem cell proliferation	P	The multiplication or reproduction of stem cells, resulting in the expansion of a stem cell population. A stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells.
72090	mesenchymal stem cell proliferation involved in nephron morphogenesis	P	The multiplication or reproduction of mesenchymal stem cells, resulting in the expansion of a stem cell population, that contributes to the shaping of a nephron.
72091	regulation of stem cell proliferation	P	Any process that modulates the frequency, rate or extent of stem cell proliferation. A stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells.
72092	ureteric bud invasion	P	The process in which the ureteric bud grows along its axis and contributes to the formation of the metanephros.
72093	metanephric renal vesicle formation	P	The developmental process pertaining to the initial formation of the metanephros.
72094	metanephric renal vesicle induction	P	Signaling at short range between cells of the ureteric bud terminus and the kidney mesenchyme that positively regulates the formation of the metanephric renal vesicle.
72095	regulation of branch elongation involved in ureteric bud branching	P	Any process that modulates the frequency, rate or extent of branch elongation involved in ureteric bud branching, the growth of a branch of the ureteric bud along its axis.
72096	negative regulation of branch elongation involved in ureteric bud branching	P	Any process that reduces the frequency, rate or extent of branch elongation involved in ureteric bud branching, the growth of a branch of the ureteric bud along its axis.
72097	negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway	P	A series of molecular signals generated as a consequence of any member of the BMP (bone morphogenetic protein) family binding to a cell surface receptor resulting in the reduction of the frequency, rate or extent of branch elongation involved in ureteric bud branching, the growth of a branch of the ureteric bud along its axis.
72098	anterior/posterior pattern specification involved in kidney development	P	The developmental process that results in the creation of defined areas or spaces within the kidney along the anterior/posterior axis to which cells respond and eventually are instructed to differentiate.
72099	anterior/posterior pattern specification involved in ureteric bud development	P	The developmental process that results in the creation of defined areas or spaces within the ureteric bud along the anterior/posterior axis to which cells respond and eventually are instructed to differentiate.
72100	specification of ureteric bud anterior/posterior symmetry	P	The establishment of the ureteric bud such that there is a similar arrangement in form and relationship of parts along its anterior/posterior axis.
72101	specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway	P	A series of molecular signals generated as a consequence of any member of the BMP (bone morphogenetic protein) family binding to a cell surface receptor that results in the establishment of the ureteric bud such that there is a similar arrangement in form and relationship of parts along its anterior/posterior axis.
72102	glomerulus morphogenesis	P	The process in which the anatomical structures of the glomerulus are generated and organized. The glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney.
72103	glomerulus vasculature morphogenesis	P	The process in which the anatomical structures of the glomerulus vasculature are generated and organized. The glomerulus vasculature is composed of the tubule structures that carry blood or lymph in the glomerulus.
72104	glomerular capillary formation	P	The process that gives rise to a glomerular capillary. This process pertains to the initial formation of a structure from unspecified parts.
72105	ureteric peristalsis	P	A wavelike sequence of involuntary muscular contraction and relaxation that passes along the ureter, impelling the contents onwards. The ureter is one of a pair of thick-walled tubes that transports urine from the kidney pelvis to the urinary bladder.
72106	regulation of ureteric bud formation	P	Any process that modulates the developmental process pertaining to the initial formation of the ureteric bud from the Wolffian duct.
72107	positive regulation of ureteric bud formation	P	Any process that increases the rate or extent of the developmental process pertaining to the initial formation of the ureteric bud from the Wolffian duct.
72108	positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis	P	Any process that increases the rate, frequency or extent of the transition where a mesenchymal cell establishes apical/basolateral polarity, forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the metanephros.
72109	glomerular mesangium development	P	The process whose specific outcome is the progression of the glomerular mesangium over time, from its formation to the mature structure. The glomerular mesangium is the thin membrane connective tissue composed of mesangial cells, which helps to support the capillary loops in a renal glomerulus.
72110	glomerular mesangial cell proliferation	P	The multiplication or reproduction of glomerular mesangial cells, resulting in the expansion of the population.
72111	cell proliferation involved in kidney development	P	The multiplication or reproduction of cells, resulting in the expansion of the population in the kidney.
72112	glomerular visceral epithelial cell differentiation	P	The process in which a relatively unspecialized cell acquires specialized features of a glomerular visceral epithelial cell. A glomerular visceral epithelial cell is a specialized epithelial cell that contains "feet" that interdigitate with the "feet" of other glomerular epithelial cells.
72113	head kidney development	P	The process whose specific outcome is the progression of the head kidney over time, from its formation to the mature structure. The head kidney is a pronephros that consists of fused bilateral lobes located in the anterior part of the kidney. It is analogous to the mammalian bone marrow and the primary site of definitive hematopoiesis.
72114	pronephros morphogenesis	P	The process in which the anatomical structures of the pronephros are generated and organized. In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensable for larval life.
72115	head kidney morphogenesis	P	The process in which the anatomical structures of the head kidney are generated and organized. The head kidney is a pronephros that consists of fused bilateral lobes located in the anterior part of the kidney.
72116	pronephros formation	P	The developmental process pertaining to the initial formation of the pronephros. In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensable for larval life.
72117	head kidney formation	P	The developmental process pertaining to the initial formation of the head kidney. The head kidney is a pronephros that consists of fused bilateral lobes located in the anterior part of the kidney.
72118	pronephros structural organization	P	The process that contributes to the act of creating the structural organization of the pronephros. This process pertains to the physical shaping of a rudimentary structure. In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensable for larval life.
72119	head kidney structural organization	P	The process that contributes to the act of creating the structural organization of the head kidney. This process pertains to the physical shaping of a rudimentary structure. The head kidney is a pronephros that consists of fused bilateral lobes located in the anterior part of the kidney.
72120	pronephros maturation	P	A developmental process, independent of morphogenetic (shape) change, that is required for the pronephros to attain its fully functional state. In mammals, the pronephros is the first of the three embryonic kidneys to be established and exists only transiently. In lower vertebrates such as fish and amphibia, the pronephros is the fully functional embryonic kidney and is indispensable for larval life.
72121	head kidney maturation	P	A developmental process, independent of morphogenetic (shape) change, that is required for the head kidney to attain its fully functional state. The head kidney is a pronephros that consists of fused bilateral lobes located in the anterior part of the kidney.
72122	extraglomerular mesangial cell proliferation	P	The multiplication or reproduction of extraglomerular glomerular mesangium cells by cell division, resulting in the expansion of their population. Extraglomerular mesangial cells (also known as lacis cells, Goormaghtigh cells) are light-staining cells in the kidney found outside the glomerulus, near the vascular pole and macula densa.
72123	intraglomerular mesangial cell proliferation	P	The multiplication or reproduction of intraglomerular glomerular mesangium cells by cell division, resulting in the expansion of their population. Intraglomerular mesangial cells are specialized pericytes located among the glomerular capillaries within a renal corpuscle of a kidney. They are required for filtration, structural support and phagocytosis.
72124	regulation of glomerular mesangial cell proliferation	P	Any process that modulates the frequency, rate or extent of glomerular mesangial cell proliferation.
72125	negative regulation of glomerular mesangial cell proliferation	P	Any process that decreases the frequency, rate or extent of glomerular mesangial cell proliferation.
72126	positive regulation of glomerular mesangial cell proliferation	P	Any process that increases the frequency, rate or extent of glomerular mesangial cell proliferation.
72127	renal capsule development	P	The process whose specific outcome is the progression of the renal capsule over time, from its formation to the mature structure. The renal capsule is the tough fibrous layer surrounding the kidney, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage. During development, it comprises a single layer of flattened cells that lie just above the cortical stroma and the condensed mesenchyme of the nephrogenic zone. It is in this region that the early stages of nephron induction and formation of new generations ureteric bud branches occur, as the kidney expands.
72128	renal capsule morphogenesis	P	The process in which the anatomical structures of the renal capsule are generated and organized. The renal capsule is the tough fibrous layer surrounding the kidney, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage. During development, it comprises a single layer of flattened cells that lie just above the cortical stroma and the condensed mesenchyme of the nephrogenic zone. It is in this region that the early stages of nephron induction and formation of new generations ureteric bud branches occur, as the kidney expands.
72129	renal capsule formation	P	The developmental process pertaining to the initial formation of a renal capsule from unspecified parts. The renal capsule is the tough fibrous layer surrounding the kidney, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage. During development, it comprises a single layer of flattened cells that lie just above the cortical stroma and the condensed mesenchyme of the nephrogenic zone. It is in this region that the early stages of nephron induction and formation of new generations ureteric bud branches occur, as the kidney expands.
72130	renal capsule specification	P	The regionalization process in which the identity of the renal capsule is specified. Identity is considered to be the aggregate of characteristics by which a structure is recognized.
72131	kidney mesenchyme morphogenesis	P	The process in which the anatomical structures of a kidney mesenchymal tissue are generated and organized. Kidney mesenchyme is the tissue made up of loosely connected mesenchymal cells in the kidney.
72132	mesenchyme morphogenesis	P	The process in which the anatomical structures of a mesenchymal tissue are generated and organized. A mesenchymal tissue is made up of loosely packed stellate cells.
72133	metanephric mesenchyme morphogenesis	P	The process in which the anatomical structures of a metanephric mesenchymal tissue are generated and organized. Metanephric mesenchyme is the tissue made up of loosely connected mesenchymal cells in the metanephros.
72134	nephrogenic mesenchyme morphogenesis	P	The process in which the anatomical structures of a nephrogenic mesenchymal tissue are generated and organized. Nephrogenic mesenchyme is the tissue made up of loosely connected mesenchymal cells in the nephron.
72135	kidney mesenchymal cell proliferation	P	The multiplication or reproduction of cells, resulting in the expansion of a mesenchymal cell population in the kidney.
72136	metanephric mesenchymal cell proliferation involved in metanephros development	P	The multiplication or reproduction of cells, resulting in the expansion of a metanephric mesenchymal cell population.
72137	condensed mesenchymal cell proliferation	P	The multiplication or reproduction of cells, resulting in the expansion of a condensed mesenchymal cell population. A condensed mesenchymal cell population is a population of adherent mesenchymal cells.
72138	mesenchymal cell proliferation involved in ureteric bud development	P	The multiplication or reproduction of cells, resulting in the expansion of a mesenchymal cell population of the ureteric bud, that contributes to ureteric bud development.
72139	glomerular parietal epithelial cell differentiation	P	The process in which a relatively unspecialized cell acquires specialized features of a glomerular parietal epithelial cell. Glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport.
72140	DCT cell development	P	The process whose specific outcome is the progression of a distal convoluted tubule cell over time, from its formation to the mature structure.
72141	renal interstitial fibroblast development	P	The process whose specific outcome is the progression of a renal interstitial fibroblast over time, from its formation to the mature structure.
72142	juxtaglomerulus cell development	P	The process whose specific outcome is the progression of a juxtaglomerulus cell over time, from its formation to the mature structure.
72143	mesangial cell development	P	The process whose specific outcome is the progression of a mesangial cell in the kidney over time, from its formation to the mature structure.
72144	glomerular mesangial cell development	P	The process whose specific outcome is the progression of a glomerular mesangial cell in the kidney over time, from its formation to the mature structure.
72145	proximal convoluted tubule segment 1 cell development	P	The process whose specific outcome is the progression of an S1 cell in the kidney over time, from its formation to the mature structure.
72146	DCT cell fate commitment	P	The process in which the developmental fate of a cell becomes restricted such that it will develop into a distal convoluted tubule cell.
72147	glomerular parietal epithelial cell fate commitment	P	The process in which the developmental fate of a cell becomes restricted such that it will develop into a glomerular parietal epithelial cell. Glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport. These cells may also give rise to podocytes.
72148	epithelial cell fate commitment	P	The process in which the developmental fate of a cell becomes restricted such that it will develop into an epithelial cell.
72149	glomerular visceral epithelial cell fate commitment	P	The process in which the developmental fate of a cell becomes restricted such that it will develop into a glomerular visceral epithelial cell. A glomerular visceral epithelial cell is a specialized epithelial cell that contains "feet" that interdigitate with the "feet" of other glomerular epithelial cells.
72150	juxtaglomerulus cell fate commitment	P	The process in which the developmental fate of a cell becomes restricted such that it will develop into a juxtaglomerulus cell.
72151	mesangial cell fate commitment	P	The process in which the developmental fate of a cell becomes restricted such that it will develop into a mesangial cell.
72152	glomerular mesangial cell fate commitment	P	The process in which the developmental fate of a cell becomes restricted such that it will develop into a glomerular mesangial cell.
72153	renal interstitial fibroblast fate commitment	P	The process in which the developmental fate of a cell becomes restricted such that it will develop into a renal fibroblast.
72154	proximal convoluted tubule segment 1 cell fate commitment	P	The process in which the developmental fate of a cell becomes restricted such that it will develop into an S1 cell in the kidney.
72155	epithelial cell migration involved in nephron tubule morphogenesis	P	The orderly movement of epithelial cells within a renal tubule that contributes to nephron tubule morphogenesis.
72156	distal tubule morphogenesis	P	The process in which the anatomical structures of a distal tubule are generated and organized. The distal tubule is a nephron tubule that begins at the macula densa and extends to the connecting tubule.
72157	epithelial cell migration involved in distal tubule morphogenesis	P	The orderly movement of epithelial cells within a renal tubule that contributes to distal tubule morphogenesis.
72158	proximal tubule morphogenesis	P	The process in which the anatomical structures of a proximal tubule are generated and organized. The proximal tubule is a nephron tubule that connects Bowman's capsule to the descending thin limb of the loop of Henle. It has a brush border epithelial morphology.
72159	epithelial cell migration involved in proximal tubule morphogenesis	P	The orderly movement of epithelial cells within a renal tubule that contributes to proximal tubule morphogenesis.
72160	nephron tubule epithelial cell differentiation	P	The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the nephron tubule as it progresses from its formation to the mature state.
72161	mesenchymal cell differentiation involved in kidney development	P	The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesenchymal cells of the kidney as it progresses from its formation to the mature state.
72162	metanephric mesenchymal cell differentiation	P	The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesenchymal cells of the metanephros as it progresses from its formation to the mature state.
72163	mesonephric epithelium development	P	The process whose specific outcome is the progression of an epithelium in the mesonephros over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure.
72164	mesonephric tubule development	P	The progression of a mesonephric tubule over time, from its initial formation to the mature structure. A mesonephric tubule is an epithelial tube that is part of the mesonephros.
72165	anterior mesonephric tubule development	P	The progression of the anterior mesonephric tubule over time, from its initial formation to the mature structure. The anterior mesonephric tubule is an epithelial tube that is part of the mesonephros.
72166	posterior mesonephric tubule development	P	The progression of the posterior mesonephric tubule over time, from its initial formation to the mature structure. The posterior mesonephric tubule is an epithelial tube that is part of the mesonephros.
72167	specification of mesonephric tubule identity	P	The process in which the tubules of the mesonephros acquire their identity.
72168	specification of anterior mesonephric tubule identity	P	The process in which the tubules of the anterior mesonephros acquire their identity.
72169	specification of posterior mesonephric tubule identity	P	The process in which the tubules of the posterior mesonephros acquire their identity.
72170	metanephric tubule development	P	The progression of a metanephric tubule over time, from its initial formation to the mature structure. A metanephric tubule is an epithelial tube that is part of the metanephros.
72171	mesonephric tubule morphogenesis	P	The process in which the anatomical structures of a mesonephric tubule are generated and organized. A mesonephric tubule is an epithelial tube that is part of the mesonephros.
72172	mesonephric tubule formation	P	The developmental process pertaining to the initial formation of a mesonephric tubule from unspecified parts. A mesonephric tubule is an epithelial tube that is part of the mesonephros.
72173	metanephric tubule morphogenesis	P	The process in which the anatomical structures of a metanephric tubule are generated and organized from an epithelium. A metanephric tubule is an epithelial tube that is part of the metanephros.
72174	metanephric tubule formation	P	The developmental process pertaining to the initial formation of a metanephric tubule.
72175	epithelial tube formation	P	The developmental process pertaining to the initial formation of an epithelial tube.
72176	nephric duct development	P	The process whose specific outcome is the progression of a nephric duct over time, from its initial formation to a mature structure. A nephric duct is a tube that drains a primitive kidney.
72177	mesonephric duct development	P	The process whose specific outcome is the progression of a mesonephric duct over time, from its initial formation to a mature structure. A mesonephric duct is a tube drains the mesonephros.
72178	nephric duct morphogenesis	P	The process in which the anatomical structures of the nephric duct are generated and organized. A nephric duct is a tube that drains a primitive kidney.
72179	nephric duct formation	P	The developmental process pertaining to the initial formation of a nephric duct. A nephric duct is a tube that drains a primitive kidney.
72180	mesonephric duct morphogenesis	P	The process in which the anatomical structures of the mesonephric duct are generated and organized. A mesonephric duct is a tube drains the mesonephros.
72181	mesonephric duct formation	P	The developmental process pertaining to the initial formation of a mesonephric duct. A mesonephric duct is a tube that drains the mesonephros.
72182	regulation of nephron tubule epithelial cell differentiation	P	Any process that modulates the frequency, rate or extent of nephron tubule epithelial cell differentiation.
72183	negative regulation of nephron tubule epithelial cell differentiation	P	Any process that decreases the frequency, rate or extent of nephron tubule epithelial cell differentiation.
72184	renal vesicle progenitor cell differentiation	P	The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the renal vesicle progenitor cells of the kidney as it progresses from its formation to the mature state. A renal vesicle progenitor cell is a cell that will give rise to terminally differentiated cells of the renal vesicle without self-renewing.
72185	metanephric cap development	P	The biological process whose specific outcome is the progression of the metanephric cap from an initial condition to its mature state. The metanephric cap is formed by the condensation of metanephric mesenchymal cells surrounding the ureteric bud tip.
72186	metanephric cap morphogenesis	P	The process in which the anatomical structures of the metanephric cap are generated and organized. The metanephric cap is formed by the condensation of metanephric mesenchymal cells surrounding the ureteric bud tip.
72187	metanephric cap formation	P	The developmental process pertaining to the initial formation of a metanephric cap from unspecified parts. The metanephric cap is formed by the condensation of metanephric mesenchymal cells surrounding the ureteric bud tip.
72188	metanephric cap specification	P	The process in which the metanephric cap acquires its identity.
72189	ureter development	P	The process whose specific outcome is the progression of the ureter over time, from its formation to the mature structure. The ureter is a muscular tube that transports urine from the kidney to the urinary bladder or from the Malpighian tubule to the hindgut.
72190	ureter urothelium development	P	The process whose specific outcome is the progression of the urothelium of the ureter over time, from its formation to the mature structure. The urothelium is an epithelium that makes up the epithelial tube of the ureter.
72191	ureter smooth muscle development	P	The process whose specific outcome is the progression of smooth muscle in the ureter over time, from its formation to the mature structure.
72192	ureter epithelial cell differentiation	P	The process in which a relatively unspecialized cell acquires specialized features of an epithelial cell in the urothelium. The urothelium is the epithelial tube of the ureter.
72193	ureter smooth muscle cell differentiation	P	The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell in the ureter.
72194	kidney smooth muscle tissue development	P	The process whose specific outcome is the progression of smooth muscle in the kidney over time, from its formation to the mature structure.
72195	kidney smooth muscle cell differentiation	P	The process in which a relatively unspecialized cell acquires specialized features of a smooth muscle cell in the kidney.
72196	proximal/distal pattern formation involved in pronephric nephron development	P	The regionalization process in which specific areas of cell differentiation are determined along a proximal/distal axis of the pronephros.
72197	ureter morphogenesis	P	The process in which the anatomical structures of the ureter are generated and organized. The ureter is a muscular tube that transports urine from the kidney to the urinary bladder.
72198	mesenchymal cell proliferation involved in ureter development	P	The multiplication or reproduction of cells, resulting in the expansion of a mesenchymal cell population of the ureter, that contributes to ureter development.
72199	regulation of mesenchymal cell proliferation involved in ureter development	P	Any process that modulates the frequency, rate or extent of mesenchymal cell proliferation that contributes to the progression of the ureter gland over time. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets.
72200	negative regulation of mesenchymal cell proliferation involved in ureter development	P	Any process that decreases the frequency, rate or extent of mesenchymal cell proliferation that contributes to the progression of the ureter gland over time. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets.
72201	negative regulation of mesenchymal cell proliferation	P	Any process that decreases the frequency, rate or extent of mesenchymal cell proliferation. A mesenchymal cell is a cell that normally gives rise to other cells that are organized as three-dimensional masses, rather than sheets.
72202	cell differentiation involved in metanephros development	P	The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the metanephros as it progresses from its formation to the mature state.
72203	cell proliferation involved in metanephros development	P	The multiplication or reproduction of cells, resulting in the expansion of the population in the metanephros.
72204	cell-cell signaling involved in metanephros development	P	Any process that mediates the transfer of information from one cell to another and contributes to the progression of the metanephros over time, from its formation to the mature organ.
72205	metanephric collecting duct development	P	The process whose specific outcome is the progression of a collecting duct in the metanephros over time, from its formation to the mature structure. The collecting duct responds to vasopressin and aldosterone to regulate water, electrolyte and acid-base balance. The collecting duct is the final common path through which urine flows before entering the ureter and then emptying into the bladder.
72206	metanephric juxtaglomerular apparatus development	P	The process whose specific outcome is the progression of the juxtaglomerular apparatus in the metanephros over time, from its formation to the mature structure. The juxtaglomerular apparatus is an anatomical structure which consists of juxtaglomerular cells, extraglomerular mesangial cells and the macula densa. The juxtaglomerular apparatus lies adjacent to the glomerulus and regulates kidney function by maintaining the blood flow to the kidney and the filtration rate.
72207	metanephric epithelium development	P	The process whose specific outcome is the progression of an epithelium in the metanephros over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure.
72208	metanephric smooth muscle tissue development	P	The process whose specific outcome is the progression of smooth muscle in the metanephros over time, from its formation to the mature structure.
72209	metanephric mesangial cell differentiation	P	The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesangial cells of the metanephros as it progresses from its formation to the mature state.
72210	metanephric nephron development	P	The process whose specific outcome is the progression of a nephron in the metanephros over time, from its formation to the mature structure. A nephron is the functional unit of the kidney.
72211	metanephric pyramids development	P	The process whose specific outcome is the progression of the metanephric pyramids over time, from their formation to the mature structures. Metanephric pyramids are the conical masses that constitute the renal medulla in a metanephros; they contain the loops of Henle and the medullary collecting ducts.
72212	regulation of transcription from RNA polymerase II promoter involved in metanephros development	P	Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that contributes to the branching morphogenesis by which the metanephros progresses from its initial formation to the mature state.
72213	metanephric capsule development	P	The process whose specific outcome is the progression of the metanephric capsule over time, from its formation to the mature structure. The metanephric capsule is the tough fibrous layer surrounding the metanephros, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage.
72214	metanephric cortex development	P	The process whose specific outcome is the progression of the metanephric cortex over time, from its formation to the mature structure. The metanephric cortex is the outer region of the metanephros.
72215	regulation of metanephros development	P	Any process that modulates the rate, frequency or extent of metanephros development. Metanephros development is the process whose specific outcome is the progression of the metanephros over time, from its formation to the mature structure. The metanephros is an endocrine and metabolic organ that filters the blood and excretes the end products of body metabolism in the form of urine.
72216	positive regulation of metanephros development	P	Any process that increases the rate, frequency or extent of metanephros development. Metanephros development is the process whose specific outcome is the progression of the metanephros over time, from its formation to the mature structure. The metanephros is an organ that filters the blood and excretes the end products of body metabolism in the form of urine.
72217	negative regulation of metanephros development	P	Any process that decreases the rate, frequency or extent of metanephros development. Metanephros development is the process whose specific outcome is the progression of the metanephros over time, from its formation to the mature structure. The metanephros is an organ that filters the blood and excretes the end products of body metabolism in the form of urine.
72218	metanephric ascending thin limb development	P	The process whose specific outcome is the progression of a metanephric ascending thin limb over time, from its formation to the mature structure. The metanephric ascending thin limb is a segment of a nephron tubule in the metanephros lying in the inner medulla that is permeable to ions but not to water and has a simple epithelium; active transepithelial solute transport is absent.
72219	metanephric cortical collecting duct development	P	The process whose specific outcome is the progression of the metanephric cortical collecting duct over time, from its formation to the mature structure. The metanephric cortical collecting duct is the portion of the metanephric collecting duct that resides in the renal cortex.
72220	metanephric descending thin limb development	P	The process whose specific outcome is the progression of the metanephric descending thin limb over time, from its formation to the mature structure. The metanephric descending thin limb is a part of the metanephric loop of Henle situated just after the proximal straight tubule (S3). It extends to the tip of the metanephric loop of Henle.
72221	metanephric distal convoluted tubule development	P	The process whose specific outcome is the progression of the metanephric distal convoluted tubule over time, from its formation to the mature structure. The metanephric distal convoluted tubule is the first segment of the metanephric nephron lying just downstream from the loop of Henle, immediately after the macula densa. Among other functions, in humans it is responsible for the reabsorption of about 5% of filtered sodium via the thiazide-sensitive Na-Cl symporter.
72222	metanephric early distal convoluted tubule development	P	The process whose specific outcome is the progression of the metanephric early distal convoluted tubule over time, from its formation to the mature structure. The metanephric early distal convoluted tubule contains metanephric DCT cells and is vasopressin-insensitive.
72223	metanephric glomerular mesangium development	P	The process whose specific outcome is the progression of the metanephric glomerular mesangium over time, from its formation to the mature structure. The metanephric glomerular mesangium is the thin membrane connective tissue composed of mesangial cells in the metanephros, which helps to support the capillary loops in a renal glomerulus.
72224	metanephric glomerulus development	P	The progression of the metanephric glomerulus over time from its initial formation until its mature state. The metanephric glomerulus is a capillary tuft which forms a close network with the visceral epithelium (podocytes) and the mesangium to form the filtration barrier and is surrounded by Bowman's capsule in nephrons of the mature vertebrate kidney, or metanephros.
72225	metanephric late distal convoluted tubule development	P	The process whose specific outcome is the progression of the metanephric late distal convoluted tubule over time, from its formation to the mature structure. The metanephric late distal convoluted tubule contains metanephric DCT cells and intercalated (IC) alpha and beta cells and is vasopressin-sensitive.
72226	metanephric long descending thin limb bend development	P	The process whose specific outcome is the progression of the metanephric long descending thin limb bend over time, from its formation to the mature structure. The metanephric long descending thin limb bend is a part of the descending thin limb of a long nephron that lies beyond the prebend segment in the metanephros.
72227	metanephric macula densa development	P	The process whose specific outcome is the progression of the metanephric macula densa over time, from its formation to the mature structure. The metanephric macula densa is an area of specialized cells in the distal tubule of the metanephros that makes contact with the vascular pole of the glomerulus.
72228	metanephric prebend segment development	P	The process whose specific outcome is the progression of the metanephric prebend segment over time, from its formation to the mature structure. The metanephric prebend segment is a part of the metanephric descending thin limb that lies before the bend and exhibits permeabilities characteristic of the ascending limb, especially negligible water permeability.
72229	metanephric proximal convoluted tubule development	P	The process whose specific outcome is the progression of the metanephric proximal convoluted tubule over time, from its formation to the mature structure. The metanephric proximal convoluted tubule is the most proximal portion of the metanephric proximal tubule and extends from the metanephric glomerular capsule to the metanephric proximal straight tubule.
72230	metanephric proximal straight tubule development	P	The process whose specific outcome is the progression of the metanephric proximal straight tubule over time, from its formation to the mature structure. The metanephric proximal straight tubule is the part of the metanephric descending limb that extends from the metanephric proximal convoluted tubule to the metanephric descending thin tubule.
72231	metanephric proximal convoluted tubule segment 1 development	P	The process whose specific outcome is the progression of the S1 portion of the metanephric proximal convoluted tubule over time, from its formation to the mature structure. The S1 portion is the initial portion of the metanephric proximal convoluted tubule and is responsible for avid reabsorption of water and solutes.
72232	metanephric proximal convoluted tubule segment 2 development	P	The process whose specific outcome is the progression of the S2 portion of the metanephric proximal convoluted tubule over time, from its formation to the mature structure. The S2 portion of the metanephric proximal tubule is involved in reabsorption of water and sodium chloride.
72233	metanephric thick ascending limb development	P	The process whose specific outcome is the progression of the metanephric thick ascending limb over time, from its formation to the mature structure. The metanephric thick ascending limb is the last part of the metanephric loop of Henle. Its thick, mitochondria-rich epithelium characterizes the outer medulla, and is responsible for very avid active salt transport. At the macula densa, the thick ascending limb connects to the distal convoluted tubule.
72234	metanephric nephron tubule development	P	The progression of a metanephric nephron tubule over time, from its initial formation to the mature structure. A metanephric nephron tubule is an epithelial tube that is part of the metanephric nephron, the functional part of the metanephros.
72235	metanephric distal tubule development	P	The process whose specific outcome is the progression of the metanephric distal tubule over time, from its formation to the mature structure. The metanephric distal tubule is a metanephric nephron tubule that begins at the metanephric macula densa and extends to the metanephric connecting tubule.
72236	metanephric loop of Henle development	P	The process whose specific outcome is the progression of the metanephric loop of Henle over time, from its formation to the mature structure. The metanephric loop of Henle is a metanephric nephron tubule that connects the proximal convoluted tubule to the distal convoluted tubule in the metanephros.
72237	metanephric proximal tubule development	P	The process whose specific outcome is the progression of the metanephric proximal tubule over time, from its formation to the mature structure. The metanephric proximal tubule is a metanephric nephron tubule that connects Bowman's capsule to the descending thin limb of the loop of Henle in the metanephros. It has a brush border epithelial morphology.
72238	metanephric long nephron development	P	The process whose specific outcome is the progression of a metanephric long nephron over time, from its formation to the mature structure. Long nephrons are associated with juxtamedullary glomeruli and extend into the inner medulla in the metanephros.
72239	metanephric glomerulus vasculature development	P	The biological process whose specific outcome is the progression of a metanephric glomerulus vasculature from an initial condition to its mature state. This process begins with the formation of the metanephric glomerulus vasculature and ends with the mature structure. The metanephric glomerulus vasculature is composed of the tubule structures that carry blood or lymph in the metanephric glomerulus.
72240	metanephric DCT cell differentiation	P	The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the distal convoluted tubule cells of the metanephros as it progresses from its formation to the mature state.
72241	metanephric DCT cell development	P	The process whose specific outcome is the progression of a metanephric distal convoluted tubule cell over time, from its formation to the mature structure.
72242	metanephric DCT cell fate commitment	P	The process in which the developmental fate of a cell becomes restricted such that it will develop into a metanephric distal convoluted tubule cell.
72243	metanephric nephron epithelium development	P	The process whose specific outcome is the progression of the metanephric nephron epithelium over time, from its formation to the mature structure. An epithelium is a tissue that covers the internal or external surfaces of an anatomical structure. The metanephric nephron epithelium is a tissue that covers the surface of a nephron in the metanephros.
72244	metanephric glomerular epithelium development	P	The process whose specific outcome is the progression of the metanephric glomerular epithelium over time, from its formation to the mature structure. The metanephric glomerular epithelium is an epithelial tissue that covers the outer surfaces of the glomerulus in the metanephros. The metanephric glomerular epithelium consists of both parietal and visceral epithelium. Metanephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport. A metanephric glomerular visceral epithelial cell is a specialized epithelial cell that contains "feet" that interdigitate with the "feet" of other glomerular epithelial cells in the metanephros.
72245	metanephric glomerular parietal epithelial cell differentiation	P	The process in which a relatively unspecialized cell acquires specialized features of a metanephric glomerular parietal epithelial cell. Metanephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport.
72246	metanephric glomerular parietal epithelial cell development	P	The process whose specific outcome is the progression of a metanephric glomerular parietal epithelial cell over time, from its formation to the mature structure. Metanephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport.
72247	metanephric glomerular parietal epithelial cell fate commitment	P	The process in which the developmental fate of a cell becomes restricted such that it will develop into a metanephric glomerular parietal epithelial cell. Metanephric glomerular parietal epithelial cells are specialized epithelial cells that form tight junctions as a barrier to protein transport. These cells may also give rise to podocytes.
72248	metanephric glomerular visceral epithelial cell differentiation	P	The process in which a relatively unspecialized cell acquires specialized features of a metanephric glomerular visceral epithelial cell. A metanephric glomerular visceral epithelial cell is a specialized epithelial cell that contains "feet" that interdigitate with the "feet" of other glomerular epithelial cells in the metanephros.
72249	metanephric glomerular visceral epithelial cell development	P	The process whose specific outcome is the progression of a metanephric glomerular visceral epithelial cell over time, from its formation to the mature structure. A metanephric glomerular visceral epithelial cell is a specialized epithelial cell that contains "feet" that interdigitate with the "feet" of other glomerular epithelial cells in the metanephros.
72250	metanephric glomerular visceral epithelial cell fate commitment	P	The process in which the developmental fate of a cell becomes restricted such that it will develop into a metanephric glomerular visceral epithelial cell. A metanephric glomerular visceral epithelial cell is a specialized epithelial cell that contains "feet" that interdigitate with the "feet" of other glomerular epithelial cells in the metanephros.
72251	metanephric juxtaglomerulus cell differentiation	P	The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the juxtaglomerulus cells of the metanephros as it progresses from its formation to the mature state.
72252	metanephric juxtaglomerulus cell development	P	The process whose specific outcome is the progression of a metanephric juxtaglomerulus cell over time, from its formation to the mature structure.
72253	metanephric juxtaglomerulus cell fate commitment	P	The process in which the developmental fate of a cell becomes restricted such that it will develop into a metanephric juxtaglomerulus cell.
72254	metanephric glomerular mesangial cell differentiation	P	The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the glomerular mesangial cells of the metanephros as it progresses from its formation to the mature state.
72255	metanephric glomerular mesangial cell development	P	The process whose specific outcome is the progression of a glomerular mesangial cell in the metanephros over time, from its formation to the mature structure.
72256	metanephric glomerular mesangial cell fate commitment	P	The process in which the developmental fate of a cell becomes restricted such that it will develop into a metanephric glomerular mesangial cell.
72257	metanephric nephron tubule epithelial cell differentiation	P	The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the cells of the metanephric nephron tubule as it progresses from its formation to the mature state.
72258	metanephric interstitial fibroblast differentiation	P	The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the interstitial fibroblasts of the metanephros as it progresses from its formation to the mature state.
72259	metanephric interstitial fibroblast development	P	The process whose specific outcome is the progression of a metanephric interstitial fibroblast over time, from its formation to the mature structure.
72260	metanephric interstitial fibroblast fate commitment	P	The process in which the developmental fate of a cell becomes restricted such that it will develop into a metanephric interstitial fibroblast.
72261	metanephric extraglomerular mesangial cell proliferation involved in metanephros development	P	The multiplication or reproduction of extraglomerular glomerular mesangium cells in the metanephros by cell division, resulting in the expansion of their population. Extraglomerular mesangial cells (also known as lacis cells, Goormaghtigh cells) are light-staining cells in the kidney found outside the glomerulus, near the vascular pole and macula densa.
72262	metanephric glomerular mesangial cell proliferation involved in metanephros development	P	The multiplication or reproduction of glomerular mesangial cells in the metanephros, resulting in the expansion of the population.
72263	metanephric intraglomerular mesangial cell proliferation	P	The multiplication or reproduction of intraglomerular glomerular mesangium cells in the metanephros by cell division, resulting in the expansion of their population. Intraglomerular mesangial cells are specialized pericytes located among the glomerular capillaries within a renal corpuscle of a kidney. They are required for filtration, structural support and phagocytosis.
72264	metanephric glomerular endothelium development	P	The process whose specific outcome is the progression of the metanephric glomerular endothelium over time, from its formation to the mature structure. The metanephric glomerular endothelium is an epithelial tissue that covers the internal surfaces of the glomerulus of the metanephros.
72265	metanephric capsule morphogenesis	P	The process in which the anatomical structures of the metanephric capsule are generated and organized. The metanephric capsule is the tough fibrous layer surrounding the metanephros, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage.
72266	metanephric capsule formation	P	The developmental process pertaining to the initial formation of a metanephric capsule from unspecified parts. The metanephric capsule is the tough fibrous layer surrounding the metanephros, covered in a thick layer of perinephric adipose tissue. It provides some protection from trauma and damage.
72267	metanephric capsule specification	P	The regionalization process in which the identity of the metanephric capsule is specified. Identity is considered to be the aggregate of characteristics by which a structure is recognized.
72268	pattern specification involved in metanephros development	P	Any developmental process that results in the creation of defined areas or spaces within the metanephros to which cells respond and eventually are instructed to differentiate.
72269	metanephric long descending thin limb development	P	The process whose specific outcome is the progression of the metanephric long descending thin limb over time, from its formation to the mature structure. The metanephric long descending thin limb is the descending thin limb of a long nephron in the metanephros that has a squamous epithelial morphology. The long descending limb starts in the inner stripe of the outer medulla and extends into the inner medulla.
72270	metanephric short nephron development	P	The process whose specific outcome is the progression of a short nephron in the metanephros over time, from its formation to the mature structure. Short nephrons are associated with mid-cortical and superficial glomeruli, are situated entirely in the outer medulla, and have no thin ascending limb.
72271	metanephric short descending thin limb development	P	The process whose specific outcome is the progression of the metanephric short descending thin limb over time, from its formation to the mature structure. The metanephric short descending thin limb is the descending thin limb of a short nephron in the metanephros that has a squamous epithelial morphology.
72272	proximal/distal pattern formation involved in metanephric nephron development	P	The regionalization process in which specific areas of cell differentiation are determined along a proximal/distal axis of a nephron in the metanephros. The proximal/distal axis is defined by a line that runs from the center of the kidney (proximal end) outward (distal end).
72273	metanephric nephron morphogenesis	P	The process in which the anatomical structures of the metanephric nephron are generated and organized. A metanephric nephron is the functional unit of the metanephros.
72274	metanephric glomerular basement membrane development	P	The process whose specific outcome is the progression of the metanephric glomerular basement membrane over time, from its formation to the mature structure. The metanephric glomerular basement membrane is the basal laminal portion of the metanephric glomerulus which performs the actual filtration.
72275	metanephric glomerulus morphogenesis	P	The process in which the anatomical structures of the metanephric glomerulus are generated and organized. The metanephric glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney, or metanephros.
72276	metanephric glomerulus vasculature morphogenesis	P	The process in which the anatomical structures of the metanephric glomerulus vasculature are generated and organized. The metanephric glomerulus vasculature is composed of the tubule structures that carry blood or lymph in the metanephric glomerulus.
72277	metanephric glomerular capillary formation	P	The process that gives rise to a metanephric glomerular capillary. This process pertains to the initial formation of a structure from unspecified parts.
72278	metanephric comma-shaped body morphogenesis	P	The process in which the metanephric comma-shaped body is generated and organized. The metanephric comma-shaped body is the precursor structure to the metanephric S-shaped body that contributes to the morphogenesis of a nephron in the metanephros.
72279	convergent extension involved in metanephric nephron morphogenesis	P	The morphogenetic process in which the renal epithelium narrows along one axis and lengthens in a perpendicular axis that contributes to the shaping of a nephron in the metanephros.
72280	establishment of planar polarity involved in metanephric nephron morphogenesis	P	Coordinated organization of groups of cells in the plane of an epithelium that contributes to the shaping of a nephron in the metanephros.
72281	mesenchymal stem cell differentiation involved in metanephric nephron morphogenesis	P	The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal stem cell that contributes to the shaping of a nephronin the metanephros. A mesenchymal stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells.
72282	metanephric nephron tubule morphogenesis	P	The process in which the anatomical structures of a metanephric nephron tubule are generated and organized. A metanephric nephron tubule is an epithelial tube that is part of the metanephric nephron, the functional part of the metanephros.
72283	metanephric renal vesicle morphogenesis	P	The process in which the anatomical structures of the metanephric renal vesicle are generated and organized. The renal vesicle is the primordial structure of the metanephric nephron epithelium, and is formed by the condensation of mesenchymal cells.
72284	metanephric S-shaped body morphogenesis	P	The process in which the metanephric S-shaped body is generated and organized. The metanephric S-shaped body is the successor of the metanephric comma-shaped body that contributes to the morphogenesis of a nephron in the metanephros.
72285	mesenchymal to epithelial transition involved in metanephric renal vesicle formation	P	A transition where a mesenchymal cell establishes apical/basolateral polarity,forms intercellular adhesive junctions, synthesizes basement membrane components and becomes an epithelial cell that will contribute to the shaping of the metanephric renal vesicle.
72286	metanephric connecting tubule development	P	The process whose specific outcome is the progression of the metanephric connecting tubule over time, from its formation to the mature structure. The metanephric connecting tubule is a tubular segment of the metanephric nephron; it connects the distal convoluted tubule to the collecting duct in the metanephros.
72287	metanephric distal tubule morphogenesis	P	The process in which the anatomical structures of a metanephric distal tubule are generated and organized. The metanephric distal tubule is a metanephric nephron tubule that begins at the macula densa and extends to the metanephric connecting tubule.
72288	metanephric proximal tubule morphogenesis	P	The process in which the anatomical structures of a metanephric proximal tubule are generated and organized. The metanephric proximal tubule is a metanephric nephron tubule that connects Bowman's capsule to the descending thin limb of the loop of Henle in the metanephros. It has a brush border epithelial morphology.
72289	metanephric nephron tubule formation	P	The developmental process pertaining to the initial formation of a metanephric nephron tubule from unspecified parts. A metanephric nephron tubule is an epithelial tube that is part of a nephron in the metanephros.
72290	epithelial cell migration involved in metanephric nephron tubule morphogenesis	P	The orderly movement of epithelial cells within a renal tubule that contributes to metanephric nephron tubule morphogenesis.
72291	epithelial cell migration involved in metanephric distal tubule morphogenesis	P	The orderly movement of epithelial cells within a renal tubule that contributes to metanephric distal tubule morphogenesis.
72292	epithelial cell migration involved in metanephric proximal tubule morphogenesis	P	The orderly movement of epithelial cells within a renal tubule that contributes to metanephric proximal tubule morphogenesis.
72293	specification of metanephric nephron tubule identity	P	The process in which the tubules arranged along the proximal/distal axis of the metanephric nephron acquire their identity.
72294	specification of metanephric connecting tubule identity	P	The process in which the connecting tubule of the metanephric nephron acquires its identity.
72295	specification of metanephric distal tubule identity	P	The process in which the distal tubule of the metanephric nephron acquires its identity.
72296	specification of metanephric loop of Henle identity	P	The process in which the loop of Henle of the metanephric nephron acquires its identity.
72297	specification of metanephric proximal tubule identity	P	The process in which the proximal tubule of the metanephric nephron acquires its identity.
72298	regulation of metanephric glomerulus development	P	Any process that modulates the rate, frequency or extent of metanephric glomerulus development, the progression of the metanephric glomerulus over time from its initial formation until its mature state. The metanephric glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney, or metanephros.
72299	negative regulation of metanephric glomerulus development	P	Any process that decreases the rate, frequency or extent of metanephric glomerulus development, the progression of the metanephric glomerulus over time from its initial formation until its mature state. The metanephric glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney, or metanephros.
72300	positive regulation of metanephric glomerulus development	P	Any process that increases the rate, frequency or extent of metanephric glomerulus development, the progression of the metanephric glomerulus over time from its initial formation until its mature state. The metanephric glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney, or metanephros.
72301	regulation of metanephric glomerular mesangial cell proliferation	P	Any process that modulates the frequency, rate or extent of metanephric glomerular mesangial cell proliferation.
72302	negative regulation of metanephric glomerular mesangial cell proliferation	P	Any process that decreases the frequency, rate or extent of metanephric glomerular mesangial cell proliferation.
72303	positive regulation of glomerular metanephric mesangial cell proliferation	P	Any process that increases the frequency, rate or extent of metanephric glomerular mesangial cell proliferation.
72304	regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis	P	Any process that modulates the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron in the metanephros.
72305	negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis	P	Any process that reduces the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron in the metanephros.
72306	positive regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis	P	Any process that increases the occurrence or rate of mesenchymal stem cell death by apoptotic process that contributes to the shaping of the nephron in the metanephros.
72307	regulation of metanephric nephron tubule epithelial cell differentiation	P	Any process that modulates the frequency, rate or extent of metanephric nephron tubule epithelial cell differentiation.
72308	negative regulation of metanephric nephron tubule epithelial cell differentiation	P	Any process that decreases the frequency, rate or extent of metanephric nephron tubule epithelial cell differentiation.
72309	mesenchymal stem cell maintenance involved in metanephric nephron morphogenesis	P	The process in which an organism retains a population of mesenchymal stem cells that contributes to the shaping of a nephron in the metanephros. A mesenchymal stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells.
72310	glomerular epithelial cell development	P	The process whose specific outcome is the progression of a glomerular epithelial cell over time, from its formation to the mature structure. Glomerular epithelial cells are specialized epithelial cells that form part of the glomerulus; there are two types, glomerular parietal epithelial cells and glomerular visceral epithelial cells.
72311	glomerular epithelial cell differentiation	P	The process in which a relatively unspecialized cell acquires specialized features of a glomerular epithelial cell. Glomerular epithelial cells are specialized epithelial cells that form part of the glomerulus; there are two types, glomerular parietal epithelial cells and glomerular visceral epithelial cells.
72312	metanephric glomerular epithelial cell differentiation	P	The process in which a relatively unspecialized cell acquires specialized features of a metanephric glomerular epithelial cell. Metanephric glomerular epithelial cells are specialized epithelial cells that form part of the metanephric glomerulus; there are two types, metanephric glomerular parietal epithelial cells and metanephric glomerular visceral epithelial cells.
72313	metanephric glomerular epithelial cell development	P	The process whose specific outcome is the progression of a metanephric glomerular epithelial cell over time, from its formation to the mature structure. Metanephric glomerular epithelial cells are specialized epithelial cells that form part of the metanephric glomerulus; there are two types, metanephric glomerular parietal epithelial cells and metanephric glomerular visceral epithelial cells.
72314	glomerular epithelial cell fate commitment	P	The process in which the developmental fate of a cell becomes restricted such that it will develop into a glomerular epithelial cell. Glomerular epithelial cells are specialized epithelial cells that form part of the glomerulus; there are two types, glomerular parietal epithelial cells and glomerular visceral epithelial cells.
72315	metanephric glomerular epithelial cell fate commitment	P	The process in which the developmental fate of a cell becomes restricted such that it will develop into a metanephric glomerular epithelial cell. Metanephric glomerular epithelial cells are specialized epithelial cells that form part of the metanephric glomerulus; there are two types, metanephric glomerular parietal epithelial cells and metanephric glomerular visceral epithelial cells.
72316	alpha-glucan catabolic process involved in ascospore release from ascus	P	The chemical reactions and pathways resulting in the breakdown of alpha-glucans in the ascus wall that contributes to the release of ascospores from the ascus.
72317	glucan endo-1,3-beta-D-glucosidase activity involved in ascospore release from ascus	F	Catalysis of the hydrolysis of 1,3-beta-D-glucosidic linkages in 1,3-beta-D-glucans that contributes to the release of ascospores from the ascus.
72318	clathrin coat disassembly	P	The disaggregation of a clathrin coat into its constituent components; results in stripping or removing the clathrin coat from clathrin-coated vesicles (CCV) before fusing with their targets. CVVs transport cargo from plasma membrane and trans-Golgi to the endosomal system.
72319	vesicle uncoating	P	A protein depolymerization process that results in the disassembly of vesicle coat proteins.
72320	volume-sensitive chloride channel activity	F	Enables the transmembrane transfer of a chloride ion by a volume-sensitive channel. A volume-sensitive channel is a channel that responds to changes in the volume of a cell.
72321	chaperone-mediated protein transport	P	The directed movement of proteins into, out of or within a cell, or between cells, mediated by chaperone molecules that bind to the transported proteins.
72322	protein transport across periplasmic space	P	The directed movement of proteins from the plasma membrane across the periplasmic space to the outer membrane or cell wall.
72323	chaperone-mediated protein transport across periplasmic space	P	The directed movement of proteins from the plasma membrane across the periplasmic space to the outer membrane, mediated by chaperone molecules that bind to the transported proteins. This process has been observed in Gram-negative bacteria.
72324	ascus epiplasm	C	Ascus cytoplasm that is not packaged into ascospores.
72325	vulval cell fate commitment	P	The process in which the cellular identity of nematode vulval cells is acquired and determined. In nematodes, the vulva is formed from ventral epidermal cells during larval stages to give rise to a fully formed adult vulva, which is the egg-laying organ of female and hermaphrodite nematodes.
72326	vulval cell fate determination	P	The process in which a cell becomes capable of differentiating autonomously into a nematode vulval cell regardless of its environment; upon determination, the cell fate cannot be reversed. In nematodes, the vulva is formed from ventral epidermal cells during larval stages to give rise to a fully formed adult vulva, which is the egg-laying organ of female and hermaphrodite nematodes.
72327	vulval cell fate specification	P	The process in which a cell becomes capable of differentiating autonomously into a nematode vulval cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed. In nematodes, the vulva is formed from ventral epidermal cells during larval stages to give rise to a fully formed adult vulva, which is the egg-laying organ of female and hermaphrodite nematodes.
72328	alkene binding	F	Interacting selectively and non-covalently with an alkene, any acyclic branched or unbranched hydrocarbon having one carbon-carbon double bond and the general formula CnH2n.
72329	monocarboxylic acid catabolic process	P	The chemical reactions and pathways resulting in the breakdown of monocarboxylic acids, any organic acid containing one carboxyl (-COOH) group.
72330	monocarboxylic acid biosynthetic process	P	The chemical reactions and pathways resulting in the formation of monocarboxylic acids, any organic acid containing one carboxyl (-COOH) group.
72331	signal transduction by p53 class mediator	P	An intracellular signaling process that is induced by the cell cycle regulator phosphoprotein p53 or an equivalent protein.
72332	intrinsic apoptotic signaling pathway by p53 class mediator	P	A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, and ends when the execution phase of apoptosis is triggered.
72334	UDP-galactose transmembrane transport	P	The directed movement of UDP-galactose across a membrane into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
72335	regulation of canonical Wnt signaling pathway involved in neural crest cell differentiation	P	Any process that modulates the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin involved in neural crest cell differentiation. The Wnt signaling pathway is the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes.
72336	negative regulation of canonical Wnt signaling pathway involved in neural crest cell differentiation	P	Any process that decreases the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin involved in neural crest cell differentiation. The Wnt signaling pathway is the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes.
72337	modified amino acid transport	P	The directed movement of modified amino acids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
72338	cellular lactam metabolic process	P	The chemical reactions and pathways involving lactams, any cyclic amides of amino carboxylic acids, having a 1-azacycloalkan-2-one structure, or analogues having unsaturation or heteroatoms replacing one or more carbon atoms of the ring.
72339	cellular lactam biosynthetic process	P	The chemical reactions and pathways resulting in the formation of lactams, any cyclic amides of amino carboxylic acids, having a 1-azacycloalkan-2-one structure, or analogues having unsaturation or heteroatoms replacing one or more carbon atoms of the ring.
72340	cellular lactam catabolic process	P	The chemical reactions and pathways resulting in the breakdown of lactams, any cyclic amides of amino carboxylic acids, having a 1-azacycloalkan-2-one structure, or analogues having unsaturation or heteroatoms replacing one or more carbon atoms of the ring.
72341	modified amino acid binding	F	Interacting selectively and non-covalently with a modified amino acid.
72342	response to anion stress	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of anion stress, an increase or decrease in the concentration of negatively charged ions in the environment.
72343	pancreatic stellate cell proliferation	P	The multiplication or reproduction of pancreatic stellate cells, resulting in the expansion of a pancreatic stellate cell population. Pancreatic stellate cells are found in the periacinar space of the exocrine pancreas and in perivascular and periductal regions of the pancreas, and have long cytoplasmic processes that encircle the base of the acinus.
72344	rescue of stalled ribosome	P	A process of translational elongation that takes place when a ribosome has stalled during translation, and results in freeing the ribosome from the stalled translation complex.
72345	NAADP-sensitive calcium-release channel activity	F	Enables the transmembrane transfer of a calcium ion by a channel that opens when nicotinic acid adenine dinucleotide phosphate (NAADP) has been bound by the channel complex or one of its constituent parts.
72346	cADPR-sensitive calcium-release channel activity	F	Enables the transmembrane transfer of a calcium ion by a channel that opens when cyclic adenosine diphosphate ribose (cADPR) has been bound by the channel complex or one of its constituent parts.
72347	response to anesthetic	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an anesthetic stimulus. An anesthetic is a substance that causes loss of feeling, awareness, or sensation.
72348	sulfur compound transport	P	The directed movement of compounds that contain sulfur, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
72349	modified amino acid transmembrane transporter activity	F	Enables the transfer of modified amino acids from one side of a membrane to the other.
72350	tricarboxylic acid metabolic process	P	The chemical reactions and pathways involving dicarboxylic acids, any organic acid containing three carboxyl (COOH) groups or anions (COO-).
72351	tricarboxylic acid biosynthetic process	P	The chemical reactions and pathways resulting in the formation of dicarboxylic acids, any organic acid containing three carboxyl (-COOH) groups.
72352	tricarboxylic acid catabolic process	P	The chemical reactions and pathways resulting in the breakdown of dicarboxylic acids, any organic acid containing three carboxyl (-COOH) groups.
72353	cellular age-dependent response to reactive oxygen species	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of reactive oxygen species, where the change varies according to the age of the cell or organism.
72354	histone kinase activity (H3-T3 specific)	F	Catalysis of the transfer of a phosphate group to the threonine-3 residue of the N-terminal tail of histone H3.
72355	histone H3-T3 phosphorylation	P	The modification of histone H3 by the addition of an phosphate group to a threonine residue at position 3 of the histone.
72356	chromosome passenger complex localization to kinetochore	P	A cellular protein complex localization that acts on a chromosome passenger complex; as a result, the complex is transported to, or maintained in, a specific location at the kinetochore. A chromosome passenger complex is a protein complex that contains the BIR-domain-containing protein Survivin, Aurora B kinase, INCENP and Borealin, and coordinates various events based on its location to different structures during the course of mitosis.
72357	PTW/PP1 phosphatase complex	C	A protein serine/threonine phosphatase complex that contains a catalytic subunit (PPP1CA, PPP1CB or PPP1CC) and the regulatory subunits PPP1R10 (PNUTS), TOX4 and WDR82, and plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase.
72358	cardiovascular system development	P	The process whose specific outcome is the progression of the cardiovascular system over time, from its formation to the mature structure. The cardiovascular system is the anatomical system that has as its parts the heart and blood vessels.
72359	circulatory system development	P	The process whose specific outcome is the progression of the circulatory system over time, from its formation to the mature structure. The circulatory system is the organ system that passes nutrients (such as amino acids and electrolytes), gases, hormones, blood cells, etc. to and from cells in the body to help fight diseases and help stabilize body temperature and pH to maintain homeostasis.
72360	vascular cord development	P	The progression of the vascular cord over time from its initial formation until its mature state. The vascular cord is the primordial vasculature that will develop into blood vessels by the process of tubulogenesis.
72361	regulation of glycolytic process by regulation of transcription from RNA polymerase II promoter	P	Any process that modulates the frequency, rate or extent of glycolysis by modulating the frequency, rate or extent of transcription from an RNA polymerase II promoter.
72362	regulation of glycolytic process by negative regulation of transcription from RNA polymerase II promoter	P	Any process that modulates the frequency, rate or extent of glycolysis by stopping, preventing, or reducing the frequency, rate or extent of transcription from an RNA polymerase II promoter.
72363	regulation of glycolytic process by positive regulation of transcription from RNA polymerase II promoter	P	Any process that modulates the frequency, rate or extent of glycolysis by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter.
72364	regulation of cellular ketone metabolic process by regulation of transcription from RNA polymerase II promoter	P	Any process that modulates the frequency, rate or extent of a cellular ketone metabolic process by modulating the frequency, rate or extent of transcription from an RNA polymerase II promoter.
72365	regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter	P	Any process that modulates the frequency, rate or extent of a cellular ketone metabolic process by stopping, preventing, or reducing the frequency, rate or extent of transcription from an RNA polymerase II promoter.
72366	regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter	P	Any process that modulates the frequency, rate or extent of a cellular ketone metabolic process by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter.
72367	regulation of lipid transport by regulation of transcription from RNA polymerase II promoter	P	Any process that modulates the frequency, rate or extent of lipid transport by modulating the frequency, rate or extent of transcription from an RNA polymerase II promoter.
72368	regulation of lipid transport by negative regulation of transcription from RNA polymerase II promoter	P	Any process that modulates the frequency, rate or extent of lipid transport by stopping, preventing, or reducing the frequency, rate or extent of transcription from an RNA polymerase II promoter.
72369	regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter	P	Any process that modulates the frequency, rate or extent of lipid transport by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter.
72370	histone H2A-S121 phosphorylation	P	The modification of histone H2A by the addition of an phosphate group to a serine residue at position 121 of the histone.
72371	histone kinase activity (H2A-S121 specific)	F	Catalysis of the transfer of a phosphate group to the serine-121 residue of the N-terminal tail of histone H2A.
72373	alpha-carotene epsilon hydroxylase activity	F	Catalysis of the reaction: alpha-carotene + NADPH + O2 + H+ = alpha-cryptoxanthin + NADP+ + H2O.
72374	carotene epsilon hydroxylase activity	F	Catalysis of the reaction: a carotene + NADPH + O2 + H+ = a beta-ring hydroxylcarotene + NADP+ + H2O. Adds a hydroxyl group to the epsilon ring of the alpha-carotene.
72375	medium-term memory	P	The memory process that deals with the storage, retrieval and modification of information received at a time ago that is intermediate between that of short and long term memory (30min - 7hrs in Drosophila melanogaster).
72376	protein activation cascade	P	A response to a stimulus that consists of a sequential series of modifications to a set of proteins where the product of one reaction acts catalytically in the following reaction. The magnitude of the response is typically amplified at each successive step in the cascade. Modifications typically include proteolysis or covalent modification, and may also include binding events.
72377	blood coagulation, common pathway	P	A protein activation cascade that contributes to blood coagulation and consists of events leading from the formation of activated factor X to the formation of active thrombin, the cleavage of fibrinogen by thrombin, and the formation of cleaved fibrin into a stable multimeric, cross-linked complex.
72378	blood coagulation, fibrin clot formation	P	A protein activation cascade that contributes to blood coagulation and consists of the cascade of enzymatic reactions initiated by physical damage to the wall of a blood vessel, leading to the formation of a formation of a fibrin clot at the site of the injury. The process also includes numerous positive and negative regulatory events.
72379	ER membrane insertion complex	C	A protein complex that is involved in the post-translational delivery of tail-anchored (TA) membrane proteins to the endoplasmic reticulum. TA membrane proteins, also called type II transmembrane proteins, contain a single C-terminal transmembrane region. Some ER membrane insertion complex subunits are conserved between different species such as mammals and budding yeast.
72380	TRC complex	C	An ER membrane insertion complex that contains subunits that recognize two types of transmembrane domain signals. In budding yeast the complex contains Get4p, Get5p, Sgt2p, and at least two heat shock proteins (HSPs).
72381	positive regulation of canonical Wnt signaling pathway involved in neural crest cell differentiation	P	Any process that increases the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin involved in neural crest cell differentiation. The Wnt signaling pathway is the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes.
72382	minus-end-directed vesicle transport along microtubule	P	The directed movement of a vesicle towards the minus end of a microtubule, mediated by motor proteins. This process begins with the attachment of a vesicle to a microtubule, and ends when the vesicle reaches its final destination.
72383	plus-end-directed vesicle transport along microtubule	P	The directed movement of a vesicle towards the plus end of a microtubule, mediated by motor proteins. This process begins with the attachment of a vesicle to a microtubule, and ends when the vesicle reaches its final destination.
72384	organelle transport along microtubule	P	The directed movement of an organelle along a microtubule, mediated by motor proteins. This process begins with the attachment of an organelle to a microtubule, and ends when the organelle reaches its final destination.
72385	minus-end-directed organelle transport along microtubule	P	The directed movement of an organelle towards the minus end of a microtubule, mediated by motor proteins. This process begins with the attachment of an organelle to a microtubule, and ends when the organelle reaches its final destination.
72386	plus-end-directed organelle transport along microtubule	P	The directed movement of an organelle towards the plus end of a microtubule, mediated by motor proteins. This process begins with the attachment of an organelle to a microtubule, and ends when the organelle reaches its final destination.
72387	flavin adenine dinucleotide metabolic process	P	The chemical reactions and pathways involving flavin adenine dinucleotide, which acts as a coenzyme or prosthetic group of various flavoprotein oxidoreductase enzymes.
72388	flavin adenine dinucleotide biosynthetic process	P	The chemical reactions and pathways resulting in the formation of flavin adenine dinucleotide, which acts as a coenzyme or prosthetic group of various flavoprotein oxidoreductase enzymes.
72389	flavin adenine dinucleotide catabolic process	P	The chemical reactions and pathways resulting in the breakdown of flavin adenine dinucleotide, which acts as a coenzyme or prosthetic group of various flavoprotein oxidoreductase enzymes.
72390	phenol metabolic process	P	The chemical reactions and pathways involving phenol, a compound that consists of a benzene ring with one attached hydroxyl group.
72391	phenol biosynthetic process	P	The chemical reactions and pathways resulting in the formation of phenol, a compound that consists of a benzene ring with one attached hydroxyl group.
72392	phenol catabolic process	P	The chemical reactions and pathways resulting in the breakdown of phenol, a compound that consists of a benzene ring with one attached hydroxyl group.
72393	microtubule anchoring at microtubule organizing center	P	Any process in which a microtubule is maintained in a specific location in a cell by attachment to a microtubule organizing center.
72394	detection of stimulus involved in cell cycle checkpoint	P	The series of events in which information about a biological process or quality is received and converted into a molecular signal, contributing to a cell cycle checkpoint.
72395	signal transduction involved in cell cycle checkpoint	P	A signal transduction process that contributes to a cell cycle checkpoint.
72396	response to cell cycle checkpoint signaling	P	A process that occurs in response to signals generated as a result of cell cycle checkpoint signaling.
72397	detection of stimulus involved in cytokinesis checkpoint	P	The series of events in which information about the formation and integrity of cytokinetic structures, such as the contractile ring, is received and converted into a molecular signal, contributing to a cytokinesis checkpoint.
72398	signal transduction involved in cytokinesis checkpoint	P	A signal transduction process that contributes to a cytokinesis checkpoint.
72399	response to cytokinesis checkpoint signaling	P	A process that occurs in response to signals generated as a result of cytokinesis checkpoint signaling.
72400	detection of stimulus involved in mitotic DNA integrity checkpoint	P	The series of events in which information about DNA integrity is received and converted into a molecular signal, contributing to a mitotic DNA integrity checkpoint.
72401	signal transduction involved in DNA integrity checkpoint	P	A signal transduction process that contributes to a DNA integrity checkpoint.
72402	response to DNA integrity checkpoint signaling	P	A process that occurs in response to signals generated as a result of DNA integrity checkpoint signaling.
72409	detection of stimulus involved in meiotic cell cycle checkpoint	P	The series of events in which information about a biological process or quality is received and converted into a molecular signal, contributing to a meiotic cell cycle checkpoint.
72410	response to meiotic cell cycle checkpoint signaling	P	A process that acts directly to delay or stop progression through the cell cycle in response to signals generated as a result of meiotic cell cycle checkpoint signaling; contributes to a meiotic cell cycle checkpoint.
72411	signal transduction involved in meiotic cell cycle checkpoint	P	A signal transduction process that contributes to a meiotic cell cycle checkpoint.
72412	detection of stimulus involved in mitotic cell cycle checkpoint	P	The series of events in which information about a biological process or quality is received and converted into a molecular signal, contributing to a mitotic cell cycle checkpoint.
72413	signal transduction involved in mitotic cell cycle checkpoint	P	A signal transduction process that contributes to a mitotic cell cycle checkpoint.
72414	response to mitotic cell cycle checkpoint signaling	P	A process that occurs in response to signals generated as a result of mitotic cell cycle checkpoint signaling.
72415	detection of stimulus involved in spindle checkpoint	P	The series of events in which information about the assembly, orientation or integrity of the spindle is received and converted into a molecular signal, contributing to a spindle checkpoint.
72416	signal transduction involved in spindle checkpoint	P	A signal transduction process that contributes to a spindle checkpoint.
72417	response to spindle checkpoint signaling	P	A process that occurs in response to signals generated as a result of spindle checkpoint signaling.
72421	detection of DNA damage stimulus involved in DNA damage checkpoint	P	The series of events in which information about damage to DNA is received and converted into a molecular signal, contributing to a DNA damage checkpoint.
72422	signal transduction involved in DNA damage checkpoint	P	A signal transduction process that contributes to a DNA damage checkpoint.
72423	response to DNA damage checkpoint signaling	P	A process that occurs in response to signals generated as a result of DNA damage checkpoint signaling.
72424	detection of DNA damage stimulus involved in G2 DNA damage checkpoint	P	The series of events in which information about damage to DNA is received and converted into a molecular signal, contributing to a G2/M transition DNA damage checkpoint.
72425	signal transduction involved in G2 DNA damage checkpoint	P	A signal transduction process that contributes to a G2/M transition DNA damage checkpoint.
72426	response to G2 DNA damage checkpoint signaling	P	A process that occurs in response to signals generated as a result of G2/M transition DNA damage checkpoint signaling.
72427	detection of DNA damage stimulus involved in intra-S DNA damage checkpoint	P	The series of events in which information about damage to DNA is received and converted into a molecular signal, contributing to an intra-S DNA damage checkpoint.
72428	signal transduction involved in intra-S DNA damage checkpoint	P	A signal transduction process that contributes to an intra-S DNA damage checkpoint.
72429	response to intra-S DNA damage checkpoint signaling	P	A process that occurs in response to signals generated as a result of intra-S DNA damage checkpoint signaling.
72430	detection of DNA damage stimulus involved in mitotic G1 DNA damage checkpoint	P	The series of events in which information about damage to DNA is received and converted into a molecular signal, contributing to a mitotic cell cycle G1/S transition DNA damage checkpoint.
72431	signal transduction involved in mitotic G1 DNA damage checkpoint	P	A signal transduction process that contributes to a mitotic cell cycle G1/S transition DNA damage checkpoint.
72432	response to G1 DNA damage checkpoint signaling	P	A process that occurs in response to signals generated as a result of G1/S transition DNA damage checkpoint signaling.
72433	detection of DNA damage stimulus involved in mitotic G2 DNA damage checkpoint	P	The series of events in which information about damage to DNA is received and converted into a molecular signal, contributing to a mitotic G2/M transition DNA damage checkpoint.
72434	signal transduction involved in mitotic G2 DNA damage checkpoint	P	A signal transduction process that contributes to a mitotic G2/M transition DNA damage checkpoint.
72435	response to mitotic G2 DNA damage checkpoint signaling	P	A process that occurs in response to signals generated as a result of mitotic G2/M transition DNA damage checkpoint signaling.
72436	detection of stimulus involved in DNA replication checkpoint	P	The series of events in which information about whether DNA replication is complete is received and converted into a molecular signal, contributing to a DNA replication checkpoint.
72437	signal transduction involved in DNA replication checkpoint	P	A signal transduction process that contributes to a DNA replication checkpoint.
72438	response to DNA replication checkpoint signaling	P	A process that occurs in response to signals generated as a result of DNA replication checkpoint signaling.
72439	detection of stimulus involved in meiotic DNA replication checkpoint	P	The series of events in which information about whether DNA replication is complete is received and converted into a molecular signal, contributing to a meiotic DNA replication checkpoint.
72440	signal transduction involved in meiotic DNA replication checkpoint	P	A signal transduction process that contributes to a meiotic DNA replication checkpoint.
72441	response to meiotic DNA replication checkpoint signaling	P	A process that occurs in response to signals generated as a result of meiotic DNA replication checkpoint signaling.
72442	detection of stimulus involved in mitotic DNA replication checkpoint	P	The series of events in which information about whether DNA replication is complete is received and converted into a molecular signal, contributing to a mitotic DNA replication checkpoint.
72443	signal transduction involved in mitotic DNA replication checkpoint	P	A signal transduction process that contributes to a mitotic DNA replication checkpoint.
72444	response to mitotic DNA replication checkpoint signaling	P	A process that occurs in response to signals generated as a result of mitotic DNA replication checkpoint signaling.
72448	detection of stimulus involved in G1 cell size control checkpoint	P	The series of events in which information about cell size is received and converted into a molecular signal, contributing to a mitotic cell cycle G1/S transition size control checkpoint.
72449	response to G1 cell size control checkpoint signaling	P	A process that occurs in response to signals generated as a result of mitotic cell cycle G1/S transition size control checkpoint signaling.
72450	signal transduction involved in G1 cell size control checkpoint	P	A signal transduction process that contributes to a mitotic cell cycle G1/S transition size control checkpoint.
72451	detection of stimulus involved in G2 cell size control checkpoint	P	The series of events in which information about cell size is received and converted into a molecular signal, contributing to a G2/M transition size control checkpoint.
72452	response to G2 transition size control checkpoint signaling	P	A process that occurs in response to signals generated as a result of G2/M transition size control checkpoint signaling.
72453	signal transduction involved in G2 cell size control checkpoint	P	A signal transduction process that contributes to a G2/M transition size control checkpoint.
72460	detection of stimulus involved in meiotic recombination checkpoint	P	The series of events in which information about whether recombination is complete is received and converted into a molecular signal, contributing to a meiotic recombination checkpoint.
72461	response to meiotic recombination checkpoint signaling	P	A process that occurs in response to signals generated as a result of meiotic recombination checkpoint signaling.
72462	signal transduction involved in meiotic recombination checkpoint	P	A signal transduction process that contributes to a meiotic recombination checkpoint.
72463	detection of stimulus involved in meiotic spindle assembly checkpoint	P	The series of events in which information about whether spindle is correctly assembled and chromosomes are attached to the spindle is received and converted into a molecular signal, contributing to a meiotic spindle assembly checkpoint.
72464	response to meiotic spindle assembly checkpoint signaling	P	A process that occurs in response to signals generated as a result of meiotic spindle assembly checkpoint signaling.
72465	signal transduction involved in meiotic spindle assembly checkpoint	P	A signal transduction process that contributes to a meiotic spindle assembly checkpoint.
72469	detection of stimulus involved in cell size control checkpoint	P	The series of events in which information about cell size is received and converted into a molecular signal, contributing to a cell size control checkpoint.
72470	response to cell size control checkpoint signaling	P	A process that occurs in response to signals generated as a result of cell size control checkpoint signaling.
72471	signal transduction involved in cell size control checkpoint	P	A signal transduction process that contributes to a cell size control checkpoint.
72475	detection of stimulus involved in mitotic spindle checkpoint	P	The series of events in which information about whether the spindle is correctly assembled and oriented, and chromosomes are attached to the spindle, is received and converted into a molecular signal, contributing to a mitotic cell cycle spindle checkpoint.
72476	response to mitotic spindle checkpoint signaling	P	A process that occurs in response to signals generated as a result of mitotic cell cycle spindle checkpoint signaling.
72477	signal transduction involved in mitotic spindle checkpoint	P	A signal transduction process that contributes to a mitotic cell cycle spindle checkpoint.
72478	detection of stimulus involved in mitotic spindle assembly checkpoint	P	The series of events in which information about whether the spindle is correctly assembled, and chromosomes are attached to the spindle, is received and converted into a molecular signal, contributing to a mitotic cell cycle spindle assembly checkpoint.
72479	response to mitotic cell cycle spindle assembly checkpoint signaling	P	A process that occurs in response to signals generated as a result of mitotic cell cycle spindle assembly checkpoint signaling.
72480	signal transduction involved in mitotic spindle assembly checkpoint	P	A signal transduction process that contributes to a mitotic cell cycle spindle assembly checkpoint.
72481	detection of stimulus involved in mitotic spindle orientation checkpoint	P	The series of events in which information about whether the spindle is correctly oriented is received and converted into a molecular signal, contributing to a mitotic cell cycle spindle orientation checkpoint.
72482	response to mitotic cell cycle spindle orientation checkpoint signaling	P	A process that occurs in response to signals generated as a result of mitotic cell cycle spindle orientation checkpoint signaling.
72483	signal transduction involved in mitotic cell cycle spindle orientation checkpoint	P	A signal transduction process that contributes to a mitotic cell cycle spindle orientation checkpoint.
72484	detection of stimulus involved in spindle assembly checkpoint	P	The series of events in which information about spindle assembly is received and converted into a molecular signal, contributing to a spindle assembly checkpoint.
72485	response to spindle assembly checkpoint signaling	P	A process that occurs in response to signals generated as a result of spindle assembly checkpoint signaling.
72486	signal transduction involved in spindle assembly checkpoint	P	A signal transduction process that contributes to a spindle assembly checkpoint.
72487	MSL complex	C	A histone acetyltransferase complex that catalyzes the acetylation of a histone H4 lysine residue at position 16. In human, it contains the catalytic subunit MOF, and MSL1, MSL2 and MSL3.
72488	ammonium transmembrane transport	P	The directed movement of ammonium across a membrane by means of some agent such as a transporter or pore. Ammonium is the cation NH4+.
72489	methylammonium transmembrane transport	P	The directed movement of methylammonium across a membrane by means of some agent such as a transporter or pore.
72490	toluene-containing compound metabolic process	P	The chemical reactions and pathways involving toluene, methylbenzene (formula C7H8), or any of its derivatives.
72491	toluene-containing compound catabolic process	P	The chemical reactions and pathways resulting in the breakdown of toluene, methylbenzene (formula C7H8), or any of its derivatives.
72492	host cell mitochondrial intermembrane space	C	The region between the inner and outer lipid bilayers of the host cell mitochondrial envelope.
72493	host cell endosome lumen	C	The volume enclosed by the membranes of the host cell endosome.
72494	host multivesicular body	C	A late endosome in which regions of the limiting host cell endosomal membrane invaginate to form internal vesicles; host membrane proteins that enter the internal vesicles are sequestered from the host cytoplasm.
72495	host cell Cajal body	C	A class of nuclear body in the eukaryotic host cell, first seen after silver staining by Ramon y Cajal in 1903, enriched in small nuclear ribonucleoproteins, and certain general RNA polymerase II transcription factors; ultrastructurally, they appear as a tangle of coiled, electron-dense threads roughly 0.5 micrometers in diameter; involved in aspects of snRNP biogenesis; the protein coilin serves as a marker for Cajal bodies. Some argue that Cajal bodies are the sites for preassembly of transcriptosomes, unitary particles involved in transcription and processing of RNA. The host is the larger of the organisms involved in a symbiotic interaction.
72496	Pup transferase activity	F	Catalysis of the transfer of Pup from one protein to another via the reaction X-Pup + Y --> Y-Pup + X, where both X-Pup and Y-Pup are covalent linkages.
72497	mesenchymal stem cell differentiation	P	The process in which a relatively unspecialized cell acquires specialized features of a mesenchymal stem cell. A mesenchymal stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells.
72498	embryonic skeletal joint development	P	The process, occurring during the embryonic phase, whose specific outcome is the progression of the skeletal joints over time, from formation to mature structure.
72499	photoreceptor cell axon guidance	P	The chemotaxis process that directs the migration of a photoreceptor cell axon growth cone to its target in the optic lobe in response to a combination of attractive and repulsive cues.
72501	cellular divalent inorganic anion homeostasis	P	Any process involved in the maintenance of an internal steady state of divalent inorganic anions at the level of a cell.
72502	cellular trivalent inorganic anion homeostasis	P	Any process involved in the maintenance of an internal steady state of trivalent inorganic anions at the level of a cell.
72503	cellular divalent inorganic cation homeostasis	P	Any process involved in the maintenance of an internal steady state of divalent cations at the level of a cell.
72504	cellular trivalent inorganic cation homeostasis	P	Any process involved in the maintenance of an internal steady state of trivalent cations at the level of a cell.
72505	divalent inorganic anion homeostasis	P	Any process involved in the maintenance of an internal steady state of divalent inorganic anions within an organism or cell.
72506	trivalent inorganic anion homeostasis	P	Any process involved in the maintenance of an internal steady state of trivalent inorganic anions within an organism or cell.
72507	divalent inorganic cation homeostasis	P	Any process involved in the maintenance of an internal steady state of divalent cations within an organism or cell.
72508	trivalent inorganic cation homeostasis	P	Any process involved in the maintenance of an internal steady state of trivalent cations within an organism or cell.
72509	divalent inorganic cation transmembrane transporter activity	F	Enables the transfer of inorganic cations with a valency of two from one side of the membrane to the other. Inorganic cations are atoms or small molecules with a positive charge that do not contain carbon in covalent linkage.
72510	trivalent inorganic cation transmembrane transporter activity	F	Enables the transfer of inorganic cations with a valency of three from one side of the membrane to the other. Inorganic cations are atoms or small molecules with a positive charge that do not contain carbon in covalent linkage.
72511	divalent inorganic cation transport	P	The directed movement of inorganic cations with a valency of two into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Inorganic cations are atoms or small molecules with a positive charge which do not contain carbon in covalent linkage.
72512	trivalent inorganic cation transport	P	The directed movement of inorganic cations with a valency of three into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Inorganic cations are atoms or small molecules with a positive charge which do not contain carbon in covalent linkage.
72513	positive regulation of secondary heart field cardioblast proliferation	P	Any process that activates or increases the frequency, rate or extent of cardioblast proliferation in the second heart field. A cardioblast is a cardiac precursor cell. It is a cell that has been committed to a cardiac fate, but will undergo more cell division rather than terminally differentiating. The secondary heart field is the region of the heart that will form the majority of the mesodermal component of the right ventricle, the arterial pole (outflow tract) and the venous pole (inflow tract).
72514	trehalose transport in response to water deprivation	P	The directed movement of trehalose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore, that occurs as a result of deprivation of water.
72515	trehalose transport in response to desiccation	P	The directed movement of trehalose into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore, that occurs as a result of a desiccation stimulus. A desiccation stimulus signals extreme dryness resulting from the prolonged deprivation of water.
72516	viral assembly compartment	C	A membrane-bounded compartment that forms in the cytoplasm of virus-infected cells, in which virus assembly takes place.
72517	host cell viral assembly compartment	C	A membrane-bounded compartment that forms in the cytoplasm of the host cell, in which virus assembly takes place.
72518	Rho-dependent protein serine/threonine kinase activity	F	Catalysis of the reaction: ATP + a protein = ADP + a phosphoprotein. This reaction requires binding of the GTPase Rho.
72519	parasitism	P	An interaction between two organisms living together in more or less intimate association in a relationship in which association is disadvantageous or destructive to one of the organisms.
72520	seminiferous tubule development	P	The reproductive developmental process whose specific outcome is the progression of the seminiferous tubule over time, from its formation to the mature structure. Seminiferous tubules are ducts located in the testicles, and are the specific location of meiosis, and the subsequent creation of gametes, namely spermatozoa.
72521	purine-containing compound metabolic process	P	The chemical reactions and pathways involving a purine-containing compound, i.e. any compound that contains purine or a formal derivative thereof.
72522	purine-containing compound biosynthetic process	P	The chemical reactions and pathways resulting in the formation of a purine-containing compound, i.e. any compound that contains purine or a formal derivative thereof.
72523	purine-containing compound catabolic process	P	The chemical reactions and pathways resulting in the breakdown of a purine-containing compound, i.e. any compound that contains purine or a formal derivative thereof.
72524	pyridine-containing compound metabolic process	P	The chemical reactions and pathways involving a pyridine-containing compound, i.e. any compound that contains pyridine or a formal derivative thereof.
72525	pyridine-containing compound biosynthetic process	P	The chemical reactions and pathways resulting in the formation of a pyridine-containing compound, i.e. any compound that contains pyridine or a formal derivative thereof.
72526	pyridine-containing compound catabolic process	P	The chemical reactions and pathways resulting in the breakdown of a pyridine-containing compound, i.e. any compound that contains pyridine or a formal derivative thereof.
72527	pyrimidine-containing compound metabolic process	P	The chemical reactions and pathways involving a pyrimidine-containing compound, i.e. any compound that contains pyrimidine or a formal derivative thereof.
72528	pyrimidine-containing compound biosynthetic process	P	The chemical reactions and pathways resulting in the formation of a pyrimidine-containing compound, i.e. any compound that contains pyrimidine or a formal derivative thereof.
72529	pyrimidine-containing compound catabolic process	P	The chemical reactions and pathways resulting in the breakdown of a pyrimidine-containing compound, i.e. any compound that contains pyrimidine or a formal derivative thereof.
72530	purine-containing compound transmembrane transport	P	The directed movement of a purine-containing compound across a membrane. A purine-containing compound is any compound that contains purine or a formal derivative thereof.
72531	pyrimidine-containing compound transmembrane transport	P	The directed movement of a pyrimidine-containing compound across a membrane. A pyrimidine-containing compound is any compound that contains pyrimidine or a formal derivative thereof.
72532	tri-(feruloyl or hydroxyferuloyl) spermidine meta-hydroxylase activity	F	Catalysis of the meta-hydroxylation of any of the three phenolic rings on triferuloyl spermidine or any of its mono- or di-(hydroxyferuloyl)-spermidine derivatives.
72533	tri-(coumaroyl or caffeoyl) spermidine meta-hydroxylase activity	F	Catalysis of the meta-hydroxylation of any of the three phenolic rings on tricoumaroyl spermidine or any of its mono- or dicaffeoyl spermidine derivatives.
72534	perineuronal net	C	A dense extracellular matrix (ECM) structure that forms around many neuronal cell bodies and dendrites late in development and is responsible for synaptic stabilization in the adult brain.
72535	tumor necrosis factor (ligand) superfamily member 11 production	P	The appearance of tumor necrosis factor superfamily member 11 (TNFSF11; RANKL) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
72536	interleukin-23 receptor complex	C	A protein complex that binds interleukin-23 and that consists of, at a minimum, a dimeric interleukin and its two receptor subunits as well as optional additional kinase subunits.
72537	fibroblast activation	P	A change in the morphology or behavior of a fibroblast resulting from exposure to an activating factor such as a cellular or soluble ligand.
72538	T-helper 17 type immune response	P	An immune response which is associated with resistance to intracellular bacteria with a key role in inflammation and tissue injury. This immune response is associated with pathological autoimmune conditions such as multiple sclerosis, arthritis and psoriasis which is typically orchestrated by the production of particular cytokines by T-helper 17 cells, most notably interleukin-17, IL-21 and IL-22.
72539	T-helper 17 cell differentiation	P	The process in which a relatively unspecialized T cell acquires the specialized features of a T-helper 17 (Th17) cell. A Th17 cell is a CD4-positive, alpha-beta T cell with the phenotype RORgamma-t-positive that produces IL-17.
72540	T-helper 17 cell lineage commitment	P	The process in which a CD4-positive, alpha-beta T cell becomes committed to becoming a T-helper 17 cell, a CD4-positive, alpha-beta T cell with the phenotype RORgamma-t-positive that produces IL-17.
72541	peroxynitrite reductase activity	F	Catalysis of the reaction: 2 R-SH + ONOO- = R-SS-R + NO2- + H2O.
72542	protein phosphatase activator activity	F	Increases the activity of a protein phosphatase, an enzyme which catalyzes of the removal of a phosphate group from a protein substrate molecule.
72544	L-DOPA binding	F	Interacting selectively and non-covalently with L-DOPA, the modified amino acid (2S)-2-amino-3-(3,4-dihydroxyphenyl)propanoic acid.
72545	tyrosine binding	F	Interacting selectively and non-covalently with2-amino-3-(4-hydroxyphenyl)propanoic acid.
72546	ER membrane protein complex	C	A transmembrane protein complex that is involved in protein folding in the endoplasmic reticulum. In S. cerevisiae, it has six members: EMC1, EMC2, AIM27, EMC4, KRE27, and EMC6.
72547	tricoumaroylspermidine meta-hydroxylase activity	F	Catalysis of the reaction: tricoumaroyl spermidine + NADPH + O2 = dicoumaroyl monocaffeoyl spermidine + NADP+ + H2O.
72548	dicoumaroyl monocaffeoyl spermidine meta-hydroxylase activity	F	Catalysis of the reaction: dicoumaroyl monocaffeoyl spermidine + NADPH + O2 = monocoumaroyl dicaffeoyl spermidine + NADP+ + H2O.
72549	monocoumaroyl dicaffeoyl spermidine meta-hydroxylase activity	F	Catalysis of the reaction: monocoumaroyl dicaffeoyl spermidine + NADPH + O2 = tricaffeoyl spermidine + NADP+ + H2O.
72550	triferuloylspermidine meta-hydroxylase activity	F	Catalysis of the reaction: triferuloyl spermidine + NADPH + O2 = diferuloyl mono-(hydroxyferuloyl) spermidine + NADP+ + H2O.
72551	diferuloyl mono-(hydroxyferuloyl) spermidine meta-hydroxylase activity	F	Catalysis of the reaction: diferuloyl mono-(hydroxyferuloyl) spermidine + NADPH + O2 = monoferuloyl di-(hydroxyferuloyl) spermidine + NADP+ + H2O.
72552	monoferuloyl di-(hydroxyferuloyl) spermidine meta-hydroxylase activity	F	Catalysis of the reaction: monoferuloyl di-(hydroxyferuloyl) spermidine + NADPH + O2 = tri-(hydroxyferuloyl) spermidine + NADP+ + H2O.
72553	terminal button organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a terminal button. A terminal button is the terminal inflated portion of the axon, containing the specialized apparatus necessary to release neurotransmitters.
72554	blood vessel lumenization	P	The process in which a developing blood vessel forms an endothelial lumen through which blood will flow.
72555	17-beta-ketosteroid reductase activity	F	Catalysis of the reaction: a 17-beta-ketosteroid + NADPH + H+ = a 17-beta-hydroxysteroid + NADP+.
72556	other organism presynaptic membrane	C	A presynaptic membrane that is part of another organism, i.e. a secondary organism with which the first organism is interacting. A presynaptic membrane is specialized area of membrane of the axon terminal that faces the plasma membrane of the neuron or muscle fiber with which the axon terminal establishes a synaptic junction; many synaptic junctions exhibit structural presynaptic characteristics, such as conical, electron-dense internal protrusions, that distinguish it from the remainder of the axon plasma membrane.
72557	IPAF inflammasome complex	C	A protein complex that consists of three components, IPAF, NAIP and caspase-1, and includes among its functions the sensing of flagellin derived from Legionella pneumophila, Salmonella typhimurium, Pseudomonas aeruginosa and Shigella flexneri.
72558	NLRP1 inflammasome complex	C	A protein complex that consists of two components, NLRP1 (NALP1) and caspase-1 or caspase-5. The exact mechanisms of NLRP1 activation remain obscure, but potassium ion efflux appears to be essential.
72559	NLRP3 inflammasome complex	C	A protein complex that consists of three components, NLRP3 (NALP3), PYCARD and caspase-1. It is activated upon exposure to whole pathogens, as well as a number of structurally diverse pathogen- and danger-associated molecular patterns (PAMPs and DAMPs) and environmental irritants. Whole pathogens demonstrated to activate the NLRP3 inflammasome complex include the fungi Candida albicans and Saccharomyces cerevisiae, bacteria that produce pore-forming toxins, including Listeria monocytogenes and Staphylococcus aureus, and viruses such as Sendai virus, adenovirus, and influenza virus.
72560	type B pancreatic cell maturation	P	A developmental process, independent of morphogenetic (shape) change, that is required for a type B pancreatic cell to attain its fully functional state. A type B pancreatic cell is a cell located towards center of the islets of Langerhans that secretes insulin.
72562	blood microparticle	C	A phospholipid microvesicle that is derived from any of several cell types, such as platelets, blood cells, endothelial cells, or others, and contains membrane receptors as well as other proteins characteristic of the parental cell. Microparticles are heterogeneous in size, and are characterized as microvesicles free of nucleic acids.
72563	endothelial microparticle	C	A blood microparticle that is derived from, and contains membrane receptors as well as other proteins characteristic of, an endothelial cell.
72564	blood microparticle formation	P	The cellular component organization process in which microparticles bud off from a parent cell. A microparticle is a phospholipid microvesicle that is derived from any of several cell types, such as platelets, blood cells, endothelial cells, or others, and contains membrane receptors as well as other proteins characteristic of the parental cell.
72565	endothelial microparticle formation	P	The cellular component organization process in which microparticles bud off from an endothelial cell.
72566	chemokine (C-X-C motif) ligand 1 production	P	The appearance of chemokine (C-X-C motif) ligand 1 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
72567	chemokine (C-X-C motif) ligand 2 production	P	The appearance of chemokine (C-X-C motif) ligand 2 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
72570	ADP-D-ribose binding	F	Interacting selectively and non-covalently with ADP-D-ribose, an ADP-aldose having ribose as the aldose fragment.
72571	mono-ADP-D-ribose binding	F	Interacting selectively and non-covalently with monomeric ADP-D-ribose, an ADP-aldose having ribose as the aldose fragment.
72572	poly-ADP-D-ribose binding	F	Interacting selectively and non-covalently with polymeric ADP-D-ribose, a polymer that is composed of poly-ADP-D-ribose units linked through 1,2-glycosidic bonds at the ribose ring.
72573	tolerance induction to lipopolysaccharide	P	Tolerance induction directed at lipopolysaccharide antigens.
72574	hepatocyte proliferation	P	The multiplication or reproduction of hepatocytes, resulting in the expansion of a cell population. Hepatocytes form the main structural component of the liver. They are specialized epithelial cells that are organized into interconnected plates called lobules.
72575	epithelial cell proliferation involved in liver morphogenesis	P	The multiplication or reproduction of epithelial cells, resulting in the expansion of a cell population that contributes to the shaping of the liver.
72576	liver morphogenesis	P	The process in which the anatomical structures of the liver are generated and organized.
72577	endothelial cell apoptotic process	P	Any apoptotic process in an endothelial cell. An endothelial cell comprises the outermost layer or lining of anatomical structures and can be squamous or cuboidal.
72578	neurotransmitter-gated ion channel clustering	P	The receptor clustering process in which neurotransmitter-gated ion channels are localized to distinct domains in the cell membrane.
72579	glycine receptor clustering	P	The receptor clustering process in which glycine receptors are localized to distinct domains in the cell membrane.
72580	bacterial-type EF-P lysine modification	P	The modification of a lysine residue in a protein to produce (2S)-2-amino-6-([(3S)-3,6-diaminohexanoyl]amino)hexanoic acid, and the subsequent hydroxylation of the modified lysine residue. This modification is observed in, and is probably unique to, the prokaryotic translation elongation factor P (EF-P).
72581	protein-N6-(L-lysyl)-L-lysine modification to protein-N6-(beta-lysyl)-L-lysine	P	The modification of an N6-(lysyl)-L-lysine residue in a protein, producing protein-N6-(beta-lysyl)-L-lysine ((2S)-2-amino-6-([(2S)-2,6-diaminohexanoyl]amino)hexanoic acid). This modification is observed in, and is probably unique to, translation elongation factor P (EF-P).
72582	17-beta-hydroxysteroid dehydrogenase (NADP+) activity	F	Catalysis of the reaction: a 17-beta-hydroxysteroid + NADP+ = a 17-oxosteroid + NADPH + H+.
72583	clathrin-dependent endocytosis	P	An endocytosis process that begins when material is taken up into clathrin-coated pits, which then pinch off to form clathrin-coated endocytic vesicles.
72584	caveolin-mediated endocytosis	P	An endocytosis process that begins when material is taken up into plasma membrane caveolae, which then pinch off to form endocytic caveolar carriers.
72585	xanthosine nucleotidase activity	F	Catalysis of the reaction: xanthosine + H2O = D-ribose + xanthine.
72586	DNA topoisomerase (ATP-hydrolyzing) regulator activity	F	Modulates the activity of ATP-hydrolyzing DNA topoisomerase. DNA topoisomerase (ATP-hydrolyzing) regulator activity catalyzes a DNA topological transformation by transiently cleaving a pair of complementary DNA strands to form a gate through which a second double-stranded DNA segment is passed, after which the severed strands in the first DNA segment are rejoined; product release is coupled to ATP binding and hydrolysis; changes the linking number in multiples of 2.
72587	DNA topoisomerase (ATP-hydrolyzing) activator activity	F	Binds to and increases the activity of ATP-hydrolyzing DNA topoisomerase. DNA topoisomerase (ATP-hydrolyzing) regulator activity catalyzes a DNA topological transformation by transiently cleaving a pair of complementary DNA strands to form a gate through which a second double-stranded DNA segment is passed, after which the severed strands in the first DNA segment are rejoined; product release is coupled to ATP binding and hydrolysis; changes the linking number in multiples of 2.
72588	box H/ACA RNP complex	C	A ribonucleoprotein complex that contains an RNA of the box H/ACA type and the four core proteins dyskerin, NOP10, NHP2, and GAR1 (human protein nomenclature). RNA pseudouridylation (isomerization of uridine to pseudouridine) is the major, and most likely the ancestral, function of H/ACA RNPs. Pseudouridylation targets include both large and small ribosomal RNAs (rRNAs), and small nuclear RNA (U2 snRNA). In addition to these catalytic H/ACA RNPs, a less abundant but more diverse class of structural H/ACA RNPs exists, which does not have pseudouridylation activity. These include the vertebrate telomerase RNP complex.
72589	box H/ACA scaRNP complex	C	A box H/ACA RNP complex that is located in the Cajal body of the nucleoplasm. In higher eukaryotes, box H/ACA RNP located in Cajal bodies mediate pseudouridylation of spliceosomal snRNAs.
72590	N-acetyl-L-aspartate-L-glutamate ligase activity	F	Catalysis of the reaction: ATP + N-acetyl-L-aspartate + L-glutamate = ADP + phosphate + N-acetylaspartyl-glutamate.
72591	citrate-L-glutamate ligase activity	F	Catalysis of the reaction: ATP + citrate + L-glutamate = ADP + phosphate + beta-citryl-L-glutamate.
72592	oxygen metabolic process	P	The chemical reactions and pathways involving diatomic oxygen (O2).
72593	reactive oxygen species metabolic process	P	The chemical reactions and pathways involving a reactive oxygen species, any molecules or ions formed by the incomplete one-electron reduction of oxygen. They contribute to the microbicidal activity of phagocytes, regulation of signal transduction and gene expression, and the oxidative damage to biopolymers.
72594	establishment of protein localization to organelle	P	The directed movement of a protein to a specific location on or in an organelle. Encompasses establishment of localization in the membrane or lumen of a membrane-bounded organelle.
72595	maintenance of protein localization in organelle	P	Any process in which a protein is maintained in a specific location a specific location on or in an organelle, and is prevented from moving elsewhere. Encompasses establishment of localization in the membrane or lumen of a membrane-bounded organelle.
72596	establishment of protein localization to chloroplast	P	The directed movement of a protein to a specific location in a chloroplast.
72597	maintenance of protein location in chloroplast	P	Any process in which a protein is maintained in a specific location in a chloroplast, and is prevented from moving elsewhere.
72598	protein localization to chloroplast	P	A process in which a protein is transported to, or maintained at, a location in a chloroplast.
72599	establishment of protein localization to endoplasmic reticulum	P	The directed movement of a protein to a specific location in the endoplasmic reticulum.
72600	establishment of protein localization to Golgi	P	The directed movement of a protein to a specific location in the Golgi apparatus.
72601	interleukin-3 secretion	P	The regulated release of interleukin-3 from a cell.
72602	interleukin-4 secretion	P	The regulated release of interleukin-4 from a cell.
72603	interleukin-5 secretion	P	The regulated release of interleukin-5 from a cell.
72604	interleukin-6 secretion	P	The regulated release of interleukin-6 from a cell.
72605	interleukin-7 secretion	P	The regulated release of interleukin-7 from a cell.
72606	interleukin-8 secretion	P	The regulated release of interleukin-8 from a cell.
72607	interleukin-9 secretion	P	The regulated release of interleukin-9 from a cell.
72608	interleukin-10 secretion	P	The regulated release of interleukin-10 from a cell.
72609	interleukin-11 secretion	P	The regulated release of interleukin-11 from a cell.
72610	interleukin-12 secretion	P	The regulated release of interleukin-12 from a cell.
72611	interleukin-13 secretion	P	The regulated release of interleukin-13 from a cell.
72612	interleukin-14 secretion	P	The regulated release of interleukin-14 from a cell.
72613	interleukin-15 secretion	P	The regulated release of interleukin-15 from a cell.
72614	interleukin-16 secretion	P	The regulated release of interleukin-16 from a cell.
72615	interleukin-17 secretion	P	The regulated release of any member of the interleukin-17 family of cytokines from a cell.
72616	interleukin-18 secretion	P	The regulated release of interleukin-18 from a cell.
72617	interleukin-19 secretion	P	The regulated release of interleukin-19 from a cell.
72618	interleukin-20 secretion	P	The regulated release of interleukin-20 from a cell.
72619	interleukin-21 secretion	P	The regulated release of interleukin-21 from a cell.
72620	interleukin-22 secretion	P	The regulated release of interleukin-22 from a cell.
72621	interleukin-23 secretion	P	The regulated release of interleukin-23 from a cell.
72622	interleukin-24 secretion	P	The regulated release of interleukin-24 from a cell.
72623	interleukin-25 secretion	P	The regulated release of interleukin-25 from a cell.
72624	interleukin-26 secretion	P	The regulated release of interleukin-26 from a cell.
72625	interleukin-27 secretion	P	The regulated release of interleukin-27 from a cell.
72626	interleukin-35 secretion	P	The regulated release of interleukin-35 from a cell.
72627	interleukin-28A production	P	The appearance of interleukin-28A due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
72628	interleukin-28A secretion	P	The regulated release of interleukin-28A from a cell.
72629	interleukin-28B production	P	The appearance of interleukin-28B due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
72630	interleukin-28B secretion	P	The regulated release of interleukin-28B from a cell.
72631	interleukin-29 production	P	The appearance of interleukin-29 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
72632	interleukin-29 secretion	P	The regulated release of interleukin-29 from a cell.
72633	interleukin-30 production	P	The appearance of interleukin-30 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
72634	interleukin-30 secretion	P	The regulated release of interleukin-30 from a cell.
72635	interleukin-31 production	P	The appearance of interleukin-31 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
72636	interleukin-31 secretion	P	The regulated release of interleukin-31 from a cell.
72637	interleukin-32 production	P	The appearance of interleukin-32 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
72638	interleukin-32 secretion	P	The regulated release of interleukin-32 from a cell.
72639	interleukin-33 production	P	The appearance of interleukin-33 due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
72640	interleukin-33 secretion	P	The regulated release of interleukin-33 from a cell.
72641	type I interferon secretion	P	The regulated release of type I interferon from a cell.
72642	interferon-alpha secretion	P	The regulated release of interferon-alpha from a cell.
72643	interferon-gamma secretion	P	The regulated release of interferon-gamma from a cell.
72644	type III interferon secretion	P	The regulated release of type III interferon from a cell. Interferon lambda is the only member of the type III interferon found so far.
72645	interferon-delta production	P	The appearance of interferon-delta due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
72646	interferon-delta secretion	P	The regulated release of interferon-delta from a cell.
72647	interferon-epsilon production	P	The appearance of interferon-epsilon due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
72648	interferon-epsilon secretion	P	The regulated release of interferon-epsilon from a cell.
72649	interferon-kappa production	P	The appearance of interferon-kappa due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
72650	interferon-kappa secretion	P	The regulated release of interferon-kappa from a cell.
72651	interferon-tau production	P	The appearance of interferon-tau due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
72652	interferon-tau secretion	P	The regulated release of interferon-tau from a cell.
72653	interferon-omega production	P	The appearance of interferon-omega due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
72654	interferon-omega secretion	P	The regulated release of interferon-omega from a cell.
72655	establishment of protein localization to mitochondrion	P	The directed movement of a protein to the mitochondrion or a part of the mitochondrion.
72656	maintenance of protein location in mitochondrion	P	Any process in which a protein is maintained in a specific location in a mitochondrion, and is prevented from moving elsewhere.
72657	protein localization to membrane	P	A process in which a protein is transported to, or maintained in, a specific location in a membrane.
72658	maintenance of protein location in membrane	P	Any process in which a protein is maintained in a specific location in a membrane, and is prevented from moving elsewhere.
72659	protein localization to plasma membrane	P	A process in which a protein is transported to, or maintained in, a specific location in the plasma membrane.
72660	maintenance of protein location in plasma membrane	P	Any process in which a protein is maintained in a specific location in the plasma membrane, and is prevented from moving elsewhere.
72661	protein targeting to plasma membrane	P	The process of directing proteins towards the plasma membrane; usually uses signals contained within the protein.
72662	protein localization to peroxisome	P	A process in which a protein is transported to, or maintained at, a location in a peroxisome.
72663	establishment of protein localization to peroxisome	P	The directed movement of a protein to a specific location in a peroxisome.
72664	maintenance of protein location in peroxisome	P	Any process in which a protein is maintained in a specific location in a peroxisome, and is prevented from moving elsewhere.
72665	protein localization to vacuole	P	A process in which a protein is transported to, or maintained at, a location in a vacuole.
72666	establishment of protein localization to vacuole	P	The directed movement of a protein to a specific location in a vacuole.
72667	maintenance of protein location in vacuole	P	Any process in which a protein is maintained in a specific location in a vacuole, and is prevented from moving elsewhere.
72669	tRNA-splicing ligase complex	C	A protein complex that catalyzes the ligation of cleaved pre-tRNAs by directly joining spliced tRNA halves to mature-sized tRNAs by incorporating the precursor-derived splice junction phosphate into the mature tRNA as a canonical 3',5'-phosphodiester.
72670	mitochondrial tRNA threonylcarbamoyladenosine modification	P	The attachment of a carbonyl group and a threonine to the amino group of the adenine residue immediately 3' of the anticodon, in mitochondrial tRNAs that decode ANN codons (where N is any base).
72671	mitochondria-associated ubiquitin-dependent protein catabolic process	P	The chemical reactions and pathways resulting in the breakdown of proteins transported from mitochondria and targeted to cytoplasmic proteasomes for degradation as a response to oxidative stress conditions.
72672	neutrophil extravasation	P	The migration of a neutrophil from the blood vessels into the surrounding tissue.
72673	lamellipodium morphogenesis	P	A process that is carried out at the cellular level and in which the structure of a lamellipodium is organized.
72674	multinuclear osteoclast differentiation	P	The process in which a relatively unspecialized monocyte acquires the specialized features of a multinuclear osteoclast. An osteoclast is a specialized phagocytic cell associated with the absorption and removal of the mineralized matrix of bone tissue.
72675	osteoclast fusion	P	The plasma membrane fusion process that results in fusion of mononuclear osteoclasts to form a multinuclear osteoclast.
72676	lymphocyte migration	P	The movement of a lymphocyte within or between different tissues and organs of the body.
72677	eosinophil migration	P	The movement of an eosinophil within or between different tissues and organs of the body.
72678	T cell migration	P	The movement of a T cell within or between different tissues and organs of the body.
72679	thymocyte migration	P	The movement of a thymocyte through distinct intrathymic niches (e.g. medulla, cortex), where it receives a unique set of developmental cues required for T-cell development.
72680	extracellular matrix-dependent thymocyte migration	P	The movement of a thymocyte through distinct intrathymic niches (e.g. medulla, cortex), where it receives a unique set of developmental cues required for T-cell development, dependent on extracellular matrix components including fibronectin, collagen and laminin.
72681	fibronectin-dependent thymocyte migration	P	The movement of a thymocyte through distinct intrathymic niches (e.g. medulla, cortex), where it receives a unique set of developmental cues required for T-cell development, dependent on fibronectin in the extracellular matrix.
72682	eosinophil extravasation	P	The migration of an eosinophil from the blood vessels into the surrounding tissue.
72683	T cell extravasation	P	The migration of a T cell from the blood vessels into the surrounding tissue.
72684	mitochondrial tRNA 3'-trailer cleavage, endonucleolytic	P	Endonucleolytic cleavage of the 3'-end of the pre-tRNA as part of the process of generating the mature 3'-end of the tRNA in the mitochondrion.
72685	Mre11 complex assembly	P	The aggregation, arrangement and bonding together of a set of components to form an Mre11 complex, a trimeric protein complex that possesses endonuclease activity and is involved in meiotic recombination, DNA repair and checkpoint signaling.
72686	mitotic spindle	C	A spindle that forms as part of mitosis. Mitotic and meiotic spindles contain distinctive complements of proteins associated with microtubules.
72687	meiotic spindle	C	A spindle that forms as part of meiosis. Several proteins, such as budding yeast Spo21p, fission yeast Spo2 and Spo13, and C. elegans mei-1, localize specifically to the meiotic spindle and are absent from the mitotic spindle.
72688	SHREC complex localization	P	Any process in which a SHREC complex is transported to, or maintained in, a specific location.
72689	MCM complex assembly	P	The aggregation, arrangement and bonding together of a set of components to form an MCM complex, a hexameric protein complex required for the initiation and regulation of DNA replication.
72690	single-celled organism vegetative growth phase	P	A phase of population growth during which single celled organisms reproduce by budding, fission, or other asexual methods.
72691	initiation of premeiotic DNA replication	P	A process of DNA-dependent DNA replication initiation that occurs as part of premeiotic DNA replication.
72693	protein targeting to prospore membrane	P	The process of directing proteins towards the prospore membrane; usually uses signals contained within the protein.
72695	regulation of DNA recombination at telomere	P	Any process that modulates the frequency, rate or extent of DNA recombination within the telomere.
72696	positive regulation of DNA recombination at telomere	P	Any process that activates or increases the frequency, rate or extent of DNA recombination within the telomere.
72697	protein localization to cell cortex	P	A process in which a protein is transported to, or maintained in, the cell cortex.
72698	protein localization to microtubule cytoskeleton	P	A cellular protein localization process in which a protein is transported to, or maintained at, a location within the microtubule cytoskeleton.
72699	protein localization to cortical microtubule cytoskeleton	P	A process in which a protein is transported to, or maintained at, a location within the cortical microtubule cytoskeleton.
72700	response to bismuth	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bismuth (Bi) stimulus.
72701	cellular response to bismuth	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bismuth (Bi) stimulus.
72702	response to methyl methanesulfonate	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methyl methanesulfonate (MMS) stimulus.
72703	cellular response to methyl methanesulfonate	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methyl methanesulfonate (MMS) stimulus.
72704	response to mercaptoethanol	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mercaptoethanol stimulus.
72705	cellular response to mercaptoethanol	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mercaptoethanol stimulus.
72706	response to sodium dodecyl sulfate	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sodium dodecyl sulfate (SDS) stimulus.
72707	cellular response to sodium dodecyl sulfate	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sodium dodecyl sulfate (SDS) stimulus.
72708	response to sorbitol	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sorbitol stimulus.
72709	cellular response to sorbitol	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sorbitol stimulus.
72710	response to hydroxyurea	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydroxyurea stimulus.
72711	cellular response to hydroxyurea	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydroxyurea stimulus.
72712	response to thiabendazole	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a thiabendazole stimulus.
72713	cellular response to thiabendazole	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a thiabendazole stimulus.
72714	response to selenite ion	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a selenite ion stimulus.
72715	cellular response to selenite ion	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a selenite ion stimulus.
72716	response to actinomycin D	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an actinomycin D stimulus.
72717	cellular response to actinomycin D	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an actinomycin D stimulus.
72718	response to cisplatin	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cisplatin stimulus.
72719	cellular response to cisplatin	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cisplatin stimulus.
72720	response to dithiothreitol	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dithiothreitol stimulus.
72721	cellular response to dithiothreitol	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dithiothreitol stimulus.
72722	response to amitrole	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amitrole stimulus.
72723	cellular response to amitrole	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amitrole stimulus.
72724	response to 4-nitroquinoline N-oxide	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 4-nitroquinoline N-oxide stimulus.
72725	cellular response to 4-nitroquinoline N-oxide	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 4-nitroquinoline N-oxide stimulus.
72726	response to CCCP	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a CCCP stimulus.
72727	cellular response to CCCP	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a CCCP stimulus.
72728	response to Gentian violet	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a Gentian violet stimulus.
72729	cellular response to Gentian violet	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a Gentian violet stimulus.
72730	response to papulacandin B	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a papulacandin B stimulus.
72731	cellular response to papulacandin B	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a papulacandin B stimulus.
72732	cellular response to calcium ion starvation	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of calcium ions.
72733	response to staurosporine	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a staurosporine stimulus.
72734	cellular response to staurosporine	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a staurosporine stimulus.
72735	response to t-BOOH	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tert-butyl hydroperoxide (t-BOOH) stimulus.
72736	cellular response to t-BOOH	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tert-butyl hydroperoxide (t-BOOH) stimulus.
72737	response to diamide	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diamide (N,N,N',N'-tetramethyldiazene-1,2-dicarboxamide) stimulus.
72738	cellular response to diamide	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diamide (N,N,N',N'-tetramethyldiazene-1,2-dicarboxamide) stimulus.
72739	response to anisomycin	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an anisomycin stimulus.
72740	cellular response to anisomycin	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an anisomycin stimulus.
72741	protein localization to cell division site	P	A cellular protein localization process in which a protein is transported to, or maintained at, the site of cell division.
72742	SAGA complex localization to transcription regulatory region	P	Any process in which a SAGA complex is transported to, or maintained in, a specific location in the transcription regulatory region of a gene.
72743	cellular response to erythromycin	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an erythromycin stimulus.
72744	cellular response to trichodermin	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a trichodermin stimulus.
72745	cellular response to antimycin A	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antimycin A stimulus.
72746	cellular response to tetracycline	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tetracycline stimulus.
72747	cellular response to chloramphenicol	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chloramphenicol stimulus.
72748	cellular response to tacrolimus	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tacrolimus stimulus.
72749	cellular response to cytochalasin B	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytochalasin B stimulus.
72750	cellular response to leptomycin B	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a leptomycin B stimulus.
72751	cellular response to L-thialysine	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-thialysine stimulus.
72752	cellular response to rapamycin	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a rapamycin stimulus.
72753	cellular response to glutathione	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glutathione stimulus.
72754	cellular response to purvalanol A	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a purvalanol A stimulus.
72755	cellular response to benomyl	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a benomyl stimulus.
72756	cellular response to paraquat	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a paraquat stimulus.
72757	cellular response to camptothecin	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a camptothecin stimulus.
72758	response to topoisomerase inhibitor	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a topoisomerase inhibitor stimulus.
72759	cellular response to topoisomerase inhibitor	P	Any process that results in a change in state or activity of a (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a topoisomerase inhibitor stimulus.
72760	cellular response to GW 7647	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a GW 7647 stimulus.
72761	cellular response to capsazepine	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a capsazepine stimulus.
72762	cellular response to carbendazim	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbendazim stimulus.
72763	cellular response to hesperadin	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hesperadin stimulus.
72764	cellular response to reversine	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a reversine stimulus.
72765	centromere localization	P	A cellular localization process in which a centromere/kinetochore is transported to, or maintained in, a specific location.
72766	centromere clustering at the mitotic nuclear envelope	P	A cellular localization process in which kinetochores/centromeres are coupled together at the nuclear periphery. This process is responsible for the Rabl-like configuration of chromosomes in the interphase nuclei. In fission yeast this occurs at a location near the old mitotic spindle pole body.
75000	response to host osmotic environment	P	Any process that results in a change in state or activity of the symbiont or its cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the osmotic conditions in or around its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75001	adhesion of symbiont infection structure to host	P	The attachment of an infection structure of the symbiont to its host via adhesion molecules, general stickiness etc., either directly or indirectly. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75002	adhesion of symbiont germination tube to host	P	The attachment of a germination tube of the symbiont to its host via adhesion molecules. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75003	adhesion of symbiont appressorium to host	P	The attachment of an appressorium of the symbiont to its host via adhesion molecules. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75004	adhesion of symbiont spore to host	P	The attachment of a spore of the symbiont to its host via adhesion molecules, general stickiness etc. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75005	spore germination on or near host	P	The physiological, developmental and morphological changes that occur in a symbiont spore following release from dormancy up to the earliest signs of growth occurring on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75006	modulation of spore germination on or near host	P	Any process that modulates the frequency, rate or extent of spore germination on or near host, which is the physiological, developmental and morphological changes that occur in a symbiont spore following release from dormancy up to the earliest signs of growth occurring on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75007	positive regulation of spore germination on or near host	P	Any process that activates, maintains or increases the frequency, rate or extent of spore germination on or near host, which is the physiological, developmental and morphological changes that occur in a symbiont spore following release from dormancy up to the earliest signs of growth occurring on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75008	negative regulation of spore germination on or near host	P	Any process that stops, prevents, or reduces the frequency, rate or extent of spore germination on or near host, which is the physiological, developmental and morphological changes that occur in a symbiont spore following release from dormancy up to the earliest signs of growth occurring on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75009	germ tube formation on or near host	P	Development of slender tubular outgrowth first produced by most symbiont spores immediately following germination on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75010	modulation of germ tube formation on or near host	P	Any process that modulates the frequency, rate or extent of germ tube formation on or near host. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75011	positive regulation of germ tube formation on or near host	P	Any process that activates, maintains or increases the frequency, rate or extent of germ tube formation on or near host. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75012	negative regulation of germ tube formation on or near host	P	Any process that stops, prevents, or reduces the frequency, rate or extent of germ tube formation on or near host. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75015	formation of infection structure on or near host	P	The process in which a symbiont structure that serves to infect the host is formed on or near its host organism. It includes physiological, developmental, and morphological changes of the symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75016	appressorium formation on or near host	P	The process in which a swollen, flattened portion of a symbiont filament is formed on or near its host organism, to adhere to and for the purpose of penetrating the host surface. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75017	regulation of appressorium formation on or near host	P	Any process that modulates the frequency, rate or extent of symbiont appressorium formation on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75018	positive regulation of appressorium formation on or near host	P	Any process that activates or increases the frequency, rate or extent of symbiont appressorium formation on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75019	negative regulation of appressorium formation on or near host	P	Any process that stops, prevents, or reduces the frequency, rate or extent of symbiont appressorium formation on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75020	calcium or calmodulin-mediated activation of appressorium formation	P	Any process that modulates the frequency, rate or extent of symbiont calcium or calmodulin-mediated signal transduction during appressorium formation on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75021	cAMP-mediated activation of appressorium formation	P	Any process that modulates the frequency, rate or extent of symbiont cAMP mediated signal transduction during appressorium formation on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75022	ethylene-mediated activation of appressorium formation	P	Any process that modulates the frequency, rate or extent of symbiont ethylene-mediated signal transduction during appressorium formation on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75023	MAPK-mediated regulation of appressorium formation	P	Any process that modulates the frequency, rate or extent of symbiont MAP kinase-mediated signal transduction during appressorium formation on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75024	phospholipase C-mediated activation of appressorium formation	P	Any process that modulates the frequency, rate or extent of symbiont phospholipase C-mediated signal transduction during appressorium formation on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75025	initiation of appressorium on or near host	P	The process in which a relatively unspecialized cell starts to acquire specialized features of the symbiont appressorium to aid in infection of the host. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75026	regulation of appressorium initiation on or near host	P	Any process that modulates the frequency, rate or extent of symbiont appressorium initiation on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75027	positive regulation of appressorium initiation on or near host	P	Any process that activates or increases the frequency, rate or extent of symbiont appressorium initiation on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75028	negative regulation of appressorium initiation on or near host	P	Any process that stops, prevents, or reduces the frequency, rate or extent symbiont appressorium initiation near or on host. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75029	formation of symbiont germ tube hook structure on or near host	P	The development of a swollen tip at the growing end of a symbiont spore which usually flattens against the host cell surface prior to appressorium formation. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75030	modulation of symbiont germ tube hook structure formation on or near host	P	Any process that modulates the frequency, rate or extent of symbiont germ tube hook structure formation on or near host. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75031	positive regulation of symbiont germ tube hook structure formation on or near host	P	Any process that activates, maintains or increases the frequency, rate or extent of symbiont germ tube hook structure formation on or near host. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75032	negative regulation of symbiont germ tube hook structure formation on or near host	P	Any process that stops, prevents, or reduces the frequency, rate or extent of symbiont germ tube hook structure formation on or near host. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75033	septum formation involved in appressorium formation on or near host	P	The process in which a symbiont partition is formed to separate the appressorium from the germination tube, occurring on or near the exterior of its host organism during appressorium formation. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75034	nuclear division involved in appressorium formation on or near host	P	The process in which nuclear division occurs within a symbiont spore that contributes to appressorium formation on or near the exterior of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75035	maturation of appressorium on or near host	P	The process in which specialized features of the symbiont appressorium are acquired post initiation, to aid in infection of the host. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75036	regulation of appressorium maturation on or near host	P	Any process that modulates the frequency, rate or extent of symbiont appressorium maturation on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75037	positive regulation of appressorium maturation on or near host	P	Any process that activates or increases the frequency, rate or extent of symbiont appressorium maturation on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75038	negative regulation of appressorium maturation on or near host	P	Any process that stops, prevents, or reduces the frequency, rate or extent symbiont appressorium maturation in, near or on host. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75039	establishment of turgor in appressorium	P	The process in which hydrostatic pressure is increased within the symbiont appressorium to breach the cuticle of the host. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75040	regulation of establishment of turgor in appressorium	P	Any process modulates the frequency, rate or extent of turgor formation in the symbiont appressorium on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75041	positive regulation of establishment of turgor in appressorium	P	Any process that activates or increases the frequency, rate or extent of turgor formation in the symbiont appressorium on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75042	negative regulation of establishment of turgor in appressorium	P	Any process that stops, prevents, or reduces the frequency, rate or extent of turgor formation in the symbiont appressorium on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75043	maintenance of turgor in appressorium by melanization	P	The process in which melanin is produced in the appressorium of the symbiont on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75044	autophagy of host cells involved in interaction with symbiont	P	The process in which the host cells digest parts of their own cytoplasm during interaction with its symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75045	regulation of formation by symbiont of haustorium for nutrient acquisition from host	P	Any process that modulates the frequency, rate or extent of symbiont haustorium formation for nutrient acquisition from host. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75046	positive regulation of formation by symbiont of haustorium for nutrient acquisition from host	P	Any process that activates or increases the frequency, rate or extent of symbiont haustorium formation for nutrient acquisition from host. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75047	negative regulation of formation by symbiont of haustorium for nutrient acquisition from host	P	Any process that stops, prevents, or reduces the frequency, rate or extent of symbiont haustorium formation for nutrient acquisition from host. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75048	cell wall strengthening in symbiont involved in entry into host	P	A process in which the cell wall of the symbiont is strengthened or thickened during penetration into the body, tissues, or cells of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75049	modulation of symbiont cell wall strengthening involved in entry into host	P	Any process that modulates the frequency, rate or extent of symbiont cell wall strengthening during entry into host. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75050	positive regulation of symbiont cell wall strengthening involved in entry into host	P	Any process that activates, maintains or increases the frequency, rate or extent of symbiont cell wall strengthening during entry into host. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75051	negative regulation of symbiont cell wall strengthening involved in entry into host	P	Any process that stops, prevents, or reduces the frequency, rate or extent of symbiont cell wall strengthening during entry into host. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75052	entry into host via a specialized structure	P	Penetration via a specialized structure of symbiont into the body, tissues, or cells of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75053	formation of symbiont penetration peg for entry into host	P	The assembly by the symbiont of a peg-like structure for the purpose of penetration into its host organism, which penetrates through the host cuticle and epidermal cell wall. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75054	modulation of symbiont penetration peg formation for entry into host	P	Any process that modulates the frequency, rate or extent of symbiont penetration peg formation for entry into host. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75055	positive regulation of symbiont penetration peg formation for entry into host	P	Any process that activates, maintains or increases the frequency, rate or extent of symbiont penetration peg formation for entry into host. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75056	negative regulation of symbiont penetration peg formation for entry into host	P	Any process that stops, prevents, or reduces the frequency, rate or extent of symbiont penetration peg formation for entry into host. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75057	initiation of symbiont penetration peg	P	The process in which a relatively unspecialized cell of the symbiont starts to acquire the characteristics of a mature penetration peg to penetrate into its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75058	modulation of symbiont penetration peg initiation	P	Any process that modulates the frequency, rate or extent of penetration peg initiation, the process in which a relatively unspecialized cell start to acquire the characteristics of a mature penetration peg when the symbiont penetrates its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75059	positive regulation of symbiont penetration peg initiation	P	Any process that activates, maintains or increases the frequency, rate or extent of symbiont penetration peg initiation, the process in which a relatively unspecialized cell starts to acquire the characteristics of a mature penetration peg during the symbiont penetrating into its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75060	negative regulation of symbiont penetration peg initiation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of symbiont penetration peg initiation, the process in which a relatively unspecialized cell starts to acquire the characteristics of a mature penetration peg during the symbiont penetrating into its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75061	formation of symbiont invasive hypha in host	P	The assembly by the symbiont of a threadlike, tubular structure, which may contain multiple nuclei and may or may not be divided internally by septa or cross-walls, for the purpose of invasive growth within its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75062	regulation of symbiont invasive hypha formation in host	P	Any process that modulates the frequency, rate or extent of symbiont invasive hypha formation within host. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75063	positive regulation of symbiont invasive hypha formation in host	P	Any process that activates, maintains or increases the frequency, rate or extent of symbiont invasive hypha formation within host. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75064	negative regulation of symbiont invasive hypha formation in host	P	Any process that stops, prevents, or reduces the frequency, rate or extent of symbiont invasive hypha formation within host. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75069	adhesion of symbiont infection cushion to host	P	The attachment of an infection cushion of the symbiont to its host via adhesion molecules. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75070	adhesion of symbiont hyphopodium to host	P	The attachment of a hyphopodium of the symbiont to its host via adhesion molecules. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75071	autophagy involved in symbiotic interaction	P	The process in which cells digest parts of their own cytoplasm during a symbiotic interaction; allows for both recycling of macromolecular constituents under conditions of cellular stress and remodeling the intracellular structure for cell differentiation. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75072	autophagy of symbiont cells involved in interaction with host	P	The process in which symbiont cells digest parts of their own cytoplasm during interaction with its host. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75073	autophagy of symbiont cells on or near host surface	P	The process in which symbiont cells digest parts of their own cytoplasm, occurring when the symbiont is on or near its host surface. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75074	spore autophagy involved in appressorium formation on or near host	P	The process in which a symbiont spore digests parts of its own cytoplasm, occurring when the appressorium forms on or near the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75075	modulation by host of symbiont adenylate cyclase activity	P	Any process in which the host organism modulates the frequency, rate or extent of the symbiont adenylate cyclase activity, which catalyze the reaction: ATP = 3',5'-cyclic AMP + diphosphate. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75076	positive regulation by host of symbiont adenylate cyclase activity	P	Any process in which the host organism activates, maintains or increases the frequency, rate or extent of the symbiont adenylate cyclase activity, which catalyze the reaction: ATP = 3',5'-cyclic AMP + diphosphate. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75077	negative regulation by host of symbiont adenylate cyclase activity	P	Any process in which the host organism stops, prevents, or reduces the frequency, rate or extent of the symbiont adenylate cyclase activity, which catalyze the reaction: ATP = 3',5'-cyclic AMP + diphosphate. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75078	modulation by host of symbiont receptor-mediated signal transduction	P	Any process in which the host organism modulates the frequency, rate or extent of receptor-mediated signal transduction in the symbiont. The receptor is defined as a protein on the cell membrane or within the cytoplasm or cell nucleus that binds to a specific molecule (a ligand) such as a neurotransmitter or a hormone or other substance, and initiates the cellular response to the ligand. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75079	positive regulation by host of symbiont receptor-mediated signal transduction	P	Any process in which the host organism activates, maintains or increases the frequency, rate or extent of receptor-mediated signal transduction in the symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75080	negative regulation by host of symbiont receptor-mediated signal transduction	P	Any process in which the host organism stops, prevents, or reduces the frequency, rate or extent of receptor-mediated signal transduction in the symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75081	modulation by host of symbiont transmembrane receptor-mediated signal transduction	P	Any process in which the host organism modulates the frequency, rate or extent of transmembrane receptor-mediated signal transduction in the symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75082	positive regulation by host of symbiont transmembrane receptor-mediated signal transduction	P	Any process in which the host organism activates, maintains or increases the frequency, rate or extent of transmembrane receptor-mediated signal transduction in the symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75083	negative regulation by host of symbiont transmembrane receptor-mediated signal transduction	P	Any process in which the host organism stops, prevents, or reduces the frequency, rate or extent of transmembrane receptor-mediated signal transduction in the symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75084	modulation by host of symbiont transmembrane receptor-mediated cAMP signal transduction	P	Any process in which the host organism modulates the frequency, rate or extent of transmembrane receptor-mediated cAMP signal transduction in the symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75085	positive regulation by host of symbiont transmembrane receptor-mediated cAMP signal transduction	P	Any process in which the host organism activates, maintains or increases the frequency, rate or extent of transmembrane receptor-mediated cAMP signal transduction in the symbiont organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75086	negative regulation by host of symbiont transmembrane receptor-mediated cAMP signal transduction	P	Any process in which the host organism stops, prevents, or reduces the frequency, rate or extent of transmembrane receptor-mediated cAMP signal transduction in the symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75087	modulation by host of symbiont G-protein coupled receptor protein signal transduction	P	Any process in which the host organism modulates the frequency, rate or extent of the symbiont G-protein coupled receptor protein signal transduction. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75088	positive regulation by host of symbiont G-protein coupled receptor protein signal transduction	P	Any process in which the host organism activates, maintains or increases the frequency, rate or extent of the symbiont G-protein coupled receptor protein signal transduction. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75089	negative regulation by host of symbiont G-protein coupled receptor protein signal transduction	P	Any process in which the host organism stops, prevents, or reduces the frequency, rate or extent of the symbiont G-protein coupled receptor protein signal transduction. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75090	modulation by host of symbiont signal transduction mediated by G-protein alpha subunit	P	Any process in which the host organism modulates the frequency, rate or extent of the symbiont signal transduction mediated by G-protein alpha subunit. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75091	positive regulation by host of symbiont signal transduction mediated by G-protein alpha subunit	P	Any process in which the host organism activates, maintains or increases the frequency, rate or extent of the symbiont signal transduction mediated by G-protein alpha subunit. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75092	negative regulation by host of symbiont signal transduction mediated by G-protein alpha subunit	P	Any process in which the host organism stops, prevents, or reduces the frequency, rate or extent of the symbiont signal transduction mediated by G-protein alpha subunit. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75093	modulation by host of symbiont signal transduction mediated by G-protein beta subunit	P	Any process in which the host organism modulates the frequency, rate or extent of the symbiont signal transduction mediated by G-protein beta subunit. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75094	positive regulation by host of symbiont signal transduction mediated by G-protein beta subunit	P	Any process in which the host organism activates, maintains or increases the frequency, rate or extent of the symbiont signal transduction mediated by G-protein beta subunit. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75095	negative regulation by host of symbiont signal transduction mediated by G-protein beta subunit	P	Any process in which the host organism stops, prevents, or reduces the frequency, rate or extent of the symbiont signal transduction mediated by G-protein beta subunit. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75096	modulation by host of symbiont signal transduction mediated by G-protein gamma subunit	P	Any process in which the host organism modulates the frequency, rate or extent of the symbiont signal transduction mediated by G-protein gamma subunit. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75097	positive regulation by host of symbiont signal transduction mediated by G-protein gamma subunit	P	Any process in which the host organism activates, maintains or increases the frequency, rate or extent of the symbiont signal transduction mediated by G-protein gamma subunit. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75098	negative regulation by host of symbiont signal transduction mediated by G-protein gamma subunit	P	Any process in which the host organism stops, prevents, or reduces the frequency, rate or extent of the symbiont signal transduction mediated by G-protein gamma subunit. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75099	modulation by host of symbiont protein kinase-mediated signal transduction	P	Any process in which the host organism modulates the frequency, rate or extent of protein kinase-mediated signal transduction in the symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75100	positive regulation by host of symbiont protein kinase-mediated signal transduction	P	Any process in which the host organism activates, maintains or increases the frequency, rate or extent of protein kinase-mediated signal transduction in the symbiont organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75101	negative regulation by host of symbiont protein kinase-mediated signal transduction	P	Any process in which the host organism stops, prevents, or reduces the frequency, rate or extent of protein kinase-mediated signal transduction in the symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75102	negative regulation by host of symbiont MAP kinase-mediated signal transduction	P	Any process in which the host organism stops, prevents, or reduces the frequency, rate or extent of the symbiont MAP kinase-mediated signal transduction. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75103	modulation by host of symbiont calcium or calmodulin-mediated signal transduction	P	Any process in which the host organism modulates the frequency, rate or extent of calcium or calmodulin-mediated signal transduction in the symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75104	positive regulation by host of symbiont calcium or calmodulin-mediated signal transduction	P	Any process in which the host organism activates, maintains or increases the frequency, rate or extent of calcium or calmodulin-mediated signal transduction in the symbiont organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75105	negative regulation by host of symbiont calcium or calmodulin-mediated signal transduction	P	Any process in which the host organism stops, prevents, or reduces the frequency, rate or extent of calcium or calmodulin-mediated signal transduction in the symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75106	modulation by symbiont of host adenylate cyclase activity	P	Any process in which the symbiont modulates the frequency, rate or extent of the host adenylate cyclase activity, which involves catalysis of the reaction: ATP = 3',5'-cyclic AMP + diphosphate. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75107	positive regulation by symbiont of host adenylate cyclase activity	P	Any process in which the symbiont activates, maintains or increases the frequency, rate or extent of the host adenylate cyclase activity, which involves catalysis of the reaction: ATP = 3',5'-cyclic AMP + diphosphate. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75108	negative regulation by symbiont of host adenylate cyclase activity	P	Any process in which the symbiont stops, prevents, or reduces the frequency, rate or extent of the host adenylate cyclase activity, which catalyze the reaction: ATP = 3',5'-cyclic AMP + diphosphate. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75109	modulation by symbiont of host receptor-mediated signal transduction	P	Any process in which the symbiont modulates the frequency, rate or extent of receptor-mediated signal transduction in the host organism. The receptor is defined as a protein on the cell membrane or within the cytoplasm or cell nucleus that binds to a specific molecule (a ligand) such as a neurotransmitter or a hormone or other substance, and initiates the cellular response to the ligand. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75110	positive regulation by symbiont of host receptor-mediated signal transduction	P	Any process in which the symbiont activates, maintains or increases the frequency, rate or extent of receptor-mediated signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75111	negative regulation by symbiont of host receptor-mediated signal transduction	P	Any process in which the symbiont stops, prevents, or reduces the frequency, rate or extent of receptor-mediated signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75112	modulation by symbiont of host transmembrane receptor-mediated signal transduction	P	Any process in which the symbiont modulates the frequency, rate or extent of transmembrane receptor-mediated signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75113	positive regulation by symbiont of host transmembrane receptor-mediated signal transduction	P	Any process in which the symbiont activates, maintains or increases the frequency, rate or extent of transmembrane receptor-mediated signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75114	negative regulation by symbiont of host transmembrane receptor-mediated signal transduction	P	Any process in which the symbiont stops, prevents, or reduces the frequency, rate or extent of transmembrane receptor-mediated signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75115	modulation by symbiont of host transmembrane receptor-mediated cAMP signal transduction	P	Any process in which the symbiont modulates the frequency, rate or extent of host transmembrane receptor-mediated cAMP signal transduction. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75116	positive regulation by symbiont of host transmembrane receptor-mediated cAMP signal transduction	P	Any process in which the symbiont activates, maintains or increases the frequency, rate or extent of host transmembrane receptor-mediated cAMP signal transduction. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75117	negative regulation by symbiont of host transmembrane receptor-mediated cAMP signal transduction	P	Any process in which the symbiont stops, prevents, or reduces the frequency, rate or extent of host transmembrane receptor-mediated cAMP signal transduction. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75118	modulation by symbiont of host G-protein coupled receptor protein signal transduction	P	Any process in which the symbiont modulates the frequency, rate or extent of the host G-protein coupled receptor protein signal transduction. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75119	positive regulation by symbiont of host G-protein coupled receptor protein signal transduction	P	Any process in which the symbiont activates, maintains or increases the frequency, rate or extent of the host G-protein coupled receptor protein signal transduction. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75120	negative regulation by symbiont of host G-protein coupled receptor protein signal transduction	P	Any process in which the symbiont stops, prevents, or reduces the frequency, rate or extent of the host G-protein coupled receptor protein signal transduction. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75121	modulation by symbiont of host signal transduction mediated by G-protein alpha subunit	P	Any process in which the symbiont modulates the frequency, rate or extent of the host signal transduction mediated by G-protein alpha subunit. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75122	positive regulation by symbiont of host signal transduction mediated by G-protein alpha subunit	P	Any process in which the symbiont activates, maintains or increases the frequency, rate or extent of the host signal transduction mediated by G-protein alpha subunit. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75123	negative regulation by symbiont of host signal transduction mediated by G-protein alpha subunit	P	Any process in which the symbiont stops, prevents, or reduces the frequency, rate or extent of the host signal transduction mediated by G-protein alpha subunit. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75124	modulation by symbiont of host signal transduction mediated by G-protein beta subunit	P	Any process in which the symbiont modulates the frequency, rate or extent of the host signal transduction mediated by G-protein beta subunit. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75125	positive regulation by symbiont of host signal transduction mediated by G-protein beta subunit	P	Any process in which the symbiont activates, maintains or increases the frequency, rate or extent of the host signal transduction mediated by G-protein beta subunit. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75126	negative regulation by symbiont of host signal transduction mediated by G-protein beta subunit	P	Any process in which the symbiont stops, prevents, or reduces the frequency, rate or extent of the host signal transduction mediated by G-protein beta subunit. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75127	modulation by symbiont of host signal transduction mediated by G-protein gamma subunit	P	Any process in which the symbiont modulates the frequency, rate or extent of the host signal transduction mediated by G-protein gamma subunit. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75128	positive regulation by symbiont of host signal transduction mediated by G-protein gamma subunit	P	Any process in which the symbiont activates, maintains or increases the frequency, rate or extent of the host signal transduction mediated by G-protein gamma subunit. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75129	negative regulation by symbiont of host signal transduction mediated by G-protein gamma subunit	P	Any process in which the symbiont stops, prevents, or reduces the frequency, rate or extent of the host signal transduction mediated by G-protein gamma subunit. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75130	modulation by symbiont of host protein kinase-mediated signal transduction	P	Any process in which the symbiont modulates the frequency, rate or extent of protein kinase-mediated signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75131	positive regulation by symbiont of host protein kinase-mediated signal transduction	P	Any process in which the symbiont activates, maintains or increases the frequency, rate or extent of protein kinase-mediated signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75132	negative regulation by symbiont of host protein kinase-mediated signal transduction	P	Any process in which the symbiont organism stops, prevents, or reduces the frequency, rate or extent of protein kinase-mediated signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75133	modulation by symbiont of host calcium or calmodulin-mediated signal transduction	P	Any process in which the symbiont modulates the frequency, rate or extent of calcium or calmodulin-mediated signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75134	positive regulation by symbiont of host calcium or calmodulin-mediated signal transduction	P	Any process in which the symbiont activates, maintains or increases the frequency, rate or extent of calcium or calmodulin-mediated signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75135	negative regulation by symbiont of host calcium or calmodulin-mediated signal transduction	P	Any process in which the symbiont organism stops, prevents, or reduces the frequency, rate or extent of calcium or calmodulin-mediated signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75136	response to host	P	Any process that results in a change in state or activity of the symbiont or its cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75137	response to host redox environment	P	Any process that results in a change in state or activity of the symbiont organism or its cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detecting the redox environment in host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75138	response to host oxygen tension environment	P	Any process that results in a change in state or activity of the symbiont or its cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detecting oxygen tension in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75139	response to host iron concentration	P	Any process that results in a change in state or activity of the symbiont or its cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detecting iron concentration in its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75140	response to host defense molecules	P	Any process that results in a change in state or activity of the symbiont or its cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detecting host defense molecules. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75141	maintenance of symbiont tolerance to host environment	P	Any process that contributes to the maintenance of a physiologic state in which the symbiont immune system does not react destructively against the components of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75142	maintenance of symbiont tolerance to host oxygen tension environment	P	Any process that contributes to the maintenance of a physiologic state in which the symbiont immune system does not react destructively against oxygen tension environment of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75143	maintenance of symbiont tolerance to host redox environment	P	Any process that contributes to the maintenance of a physiologic state in which the symbiont immune system does not react destructively against redox environment of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75144	maintenance of symbiont tolerance to host iron concentration	P	Any process that contributes to the maintenance of a physiologic state in which the symbiont immune system does not react destructively against iron concentration environment of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75145	maintenance of symbiont tolerance to host defense molecules	P	Any process that contributes to the maintenance of a physiologic state in which the symbiont immune system does not react destructively against defense molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75146	maintenance of symbiont tolerance to host osmotic environment	P	Any process that contributes to the maintenance of a physiologic state in which the symbiont immune system does not react destructively against osmotic environment of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75147	regulation of signal transduction in response to host	P	Any process in which the symbiont organism modulates the frequency, rate or extent of its signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75148	positive regulation of signal transduction in response to host	P	Any process in which the symbiont organism activates, maintains or increases the frequency, rate or extent of its signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75149	negative regulation of signal transduction in response to host	P	Any process in which the symbiont organism stops, prevents, or reduces the frequency, rate or extent of its signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75150	regulation of receptor-mediated signal transduction in response to host	P	Any process in which the symbiont organism modulates the frequency, rate or extent of its receptor-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75151	positive regulation of receptor-mediated signal transduction in response to host	P	Any process in which the symbiont organism activates, maintains or increases the frequency, rate or extent of its receptor-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75152	negative regulation of receptor-mediated signal transduction in response to host	P	Any process in which the symbiont organism stops, prevents, or reduces the frequency, rate or extent of its symbiont receptor-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75153	regulation of transmembrane receptor-mediated signal transduction in response to host	P	Any process in which the symbiont organism modulates the frequency, rate or extent of its transmembrane receptor-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75154	positive regulation of transmembrane receptor-mediated signal transduction in response to host	P	Any process in which the symbiont organism activates, maintains or increases the frequency, rate or extent of its transmembrane receptor-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75155	negative regulation of transmembrane receptor-mediated signal transduction in response to host	P	Any process in which the symbiont organism stops, prevents, or reduces the frequency, rate or extent of its symbiont transmembrane receptor-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75156	regulation of G-protein coupled receptor protein signaling pathway in response to host	P	Any process in which the symbiont organism modulates the frequency, rate or extent of its G-protein coupled receptor protein-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75157	positive regulation of G-protein coupled receptor protein signaling pathway in response to host	P	Any process in which the symbiont organism activates, maintains or increases the frequency, rate or extent of its G-protein coupled receptor protein-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75158	negative regulation of G-protein coupled receptor protein signaling pathway in response to host	P	Any process in which the symbiont organism stops, prevents, or reduces the frequency, rate or extent of its symbiont G-protein coupled receptor protein-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75159	regulation of G-protein alpha subunit-mediated signal transduction in response to host	P	Any process in which the symbiont organism modulates the frequency, rate or extent of its G-protein alpha subunit-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75160	positive regulation of G-protein alpha subunit-mediated signal transduction in response to host	P	Any process in which the symbiont organism activates, maintains or increases the frequency, rate or extent of its G-protein alpha subunit-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75161	negative regulation of G-protein alpha subunit-mediated signal transduction in response to host	P	Any process in which the symbiont organism stops, prevents, or reduces the frequency, rate or extent of its symbiont G-protein alpha subunit-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75162	regulation of G-protein beta subunit-mediated signal transduction in response to host	P	Any process in which the symbiont organism modulates the frequency, rate or extent of its G-protein beta subunit-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75163	positive regulation of G-protein beta subunit-mediated signal transduction in response to host	P	Any process in which the symbiont organism activates, maintains or increases the frequency, rate or extent of its G-protein beta subunit-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75164	negative regulation of G-protein beta subunit-mediated signal transduction in response to host	P	Any process in which the symbiont organism stops, prevents, or reduces the frequency, rate or extent of its symbiont G-protein beta subunit-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75165	regulation of G-protein gamma subunit-mediated signal transduction in response to host	P	Any process in which the symbiont organism modulates the frequency, rate or extent of its G-protein gamma subunit-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75166	positive regulation of G-protein gamma subunit-mediated signal transduction in response to host	P	Any process in which the symbiont organism activates, maintains or increases the frequency, rate or extent of its G-protein gamma subunit-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75167	negative regulation of G-protein gamma subunit-mediated signal transduction in response to host	P	Any process in which the symbiont organism stops, prevents, or reduces the frequency, rate or extent of its symbiont G-protein gamma subunit-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75168	regulation of protein kinase-mediated signal transduction in response to host	P	Any process in which the symbiont organism modulates the frequency, rate or extent of its protein kinase-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75169	positive regulation of symbiont protein kinase-mediated signal transduction in response to host	P	Any process in which the symbiont organism activates, maintains or increases the frequency, rate or extent of its protein kinase-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75170	negative regulation of protein kinase-mediated signal transduction in response to host	P	Any process in which the symbiont organism stops, prevents, or reduces the frequency, rate or extent of its symbiont protein kinase-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75171	regulation of MAP kinase-mediated signal transduction in response to host	P	Any process in which the symbiont organism modulates the frequency, rate or extent of its MAP kinase-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75172	positive regulation of MAP kinase-mediated signal transduction in response to host	P	Any process in which the symbiont organism activates, maintains or increases the frequency, rate or extent of its MAP kinase-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75173	negative regulation of MAP kinase-mediated signal transduction in response to host	P	Any process in which the symbiont organism stops, prevents, or reduces the frequency, rate or extent of its symbiont MAP kinase-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75174	regulation of cAMP-mediated signaling in response to host	P	Any process in which the symbiont organism modulates the frequency, rate or extent of its cAMP-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75175	positive regulation of cAMP-mediated signaling in response to host	P	Any process in which the symbiont organism activates, maintains or increases the frequency, rate or extent of its cAMP-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75176	negative regulation of cAMP-mediated signaling in response to host	P	Any process in which the symbiont organism stops, prevents, or reduces the frequency, rate or extent of its cAMP-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75177	regulation of calcium or calmodulin-mediated signal transduction in response to host	P	Any process in which the symbiont organism modulates the frequency, rate or extent of its calcium or calmodulin-mediated signal transduction as a result of detecting host molecules in, on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75178	positive regulation of calcium or calmodulin-mediated signal transduction in response to host	P	Any process in which the symbiont organism activates, maintains or increases the frequency, rate or extent of its calcium or calmodulin-mediated signal transduction as a result of detecting host molecules in, on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75179	negative regulation of calcium or calmodulin-mediated signal transduction in response to host	P	Any process in which the symbiont organism stops, prevents, or reduces the frequency, rate or extent of its symbiont calcium or calmodulin-mediated signal transduction as a result of detecting host molecules in, on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75180	regulation of transcription in response to host	P	Any process in which the symbiont organism modulates the frequency, rate or extent of its transcription as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75181	positive regulation of symbiont transcription in response to host	P	Any process in which an organism activates, maintains or increases the frequency, rate or extent of its transcription as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75182	negative regulation of symbiont transcription in response to host	P	Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of its transcription as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75183	infection cushion formation on or near host	P	The process in which an organized mass of hyphae is formed on or near the host organism, and numerous infective hyphae develop from the hyphae mass. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75184	regulation of infection cushion formation on or near host	P	Any process that modulates the frequency, rate or extent of symbiont infection cushion formation on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75185	positive regulation of infection cushion formation on or near host	P	Any process that activates or increases the frequency, rate or extent of symbiont infection cushion formation on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75186	negative regulation of infection cushion formation on or near host	P	Any process that stops, prevents, or reduces the frequency, rate or extent of symbiont infection cushion formation on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75187	hyphopodium formation on or near host	P	The process in which a specialized structure, consisted of stalked, thick-walled, lobed cells of vegetative epiphytic hyphae, is formed, to attach and penetrate the host surface. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75188	regulation of hyphopodium formation on or near host	P	Any process that modulates the frequency, rate or extent of symbiont hyphopodium formation on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75189	positive regulation of hyphopodium formation on or near host	P	Any process that activates or increases the frequency, rate or extent of symbiont hyphopodium formation on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75190	negative regulation of hyphopodium formation on or near host	P	Any process that stops, prevents, or reduces the frequency, rate or extent of symbiont hyphopodium formation on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75191	autophagy of host cells on or near symbiont surface	P	The process in which the host cells digest parts of their own cytoplasm, occurring when the host is on or near its symbiont surface. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75192	haustorium mother cell formation on or near host	P	The process in which a symbiont cell is formed on or near its host organism, via separated from the tip of an infection hypha by a septum. The haustorium mother cell usually contains 2-4 fungal nuclei, and its function is to attach and penetrate the host. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75193	regulation of haustorium mother cell formation on or near host	P	Any process that modulates the frequency, rate or extent of symbiont haustorium mother cell formation on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75194	positive regulation of haustorium mother cell formation on or near host	P	Any process that activates or increases the frequency, rate or extent of symbiont haustorium mother cell formation on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75195	negative regulation of haustorium mother cell formation on or near host	P	Any process that stops, prevents, or reduces the frequency, rate or extent of symbiont haustorium mother cell formation on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75196	adhesion of symbiont haustorium mother cell to host	P	The attachment of a haustorium mother cell of the symbiont to its host via adhesion molecules. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75197	formation of symbiont haustorium neck for entry into host	P	The assembly by the symbiont of a neck-like structure for the purpose of penetration into its host organism. The neck-like structure connects haustorium mother cell and haustorium. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75198	modulation of symbiont haustorium neck formation for entry into host	P	Any process that modulates the frequency, rate or extent of symbiont haustorium neck formation for entry into host. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75199	positive regulation of symbiont haustorium neck formation for entry into host	P	Any process that activates, maintains or increases the frequency, rate or extent of symbiont haustorium neck formation for entry into host. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75200	negative regulation of symbiont haustorium neck formation for entry into host	P	Any process that stops, prevents, or reduces the frequency, rate or extent of symbiont haustorium neck formation for entry into host. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75201	formation of symbiont penetration hypha for entry into host	P	The assembly by the symbiont of a threadlike, tubular structure, which may contain multiple nuclei and may or may not be divided internally by septa or cross-walls, for the purpose of penetration into its host organism. In the case of an appressorium existing, this term is defined in further details as the process in which the symbiont penetration peg expands to form a hypha which traverses the epidermal cell and emerges into the intercellular space of the mesophyll tissue. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75202	modulation of symbiont penetration hypha formation for entry into host	P	Any process that modulates the frequency, rate or extent of symbiont penetration hypha formation for entry into host. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75203	positive regulation of symbiont penetration hypha formation for entry into host	P	Any process that activates, maintains or increases the frequency, rate or extent of symbiont penetration hypha formation for entry into host. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75204	negative regulation of symbiont penetration hypha formation for entry into host	P	Any process that stops, prevents, or reduces the frequency, rate or extent of symbiont penetration hypha formation for entry into host. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75205	modulation by host of symbiont cAMP-mediated signal transduction	P	Any process in which the host organism modulates the frequency, rate or extent of cAMP-mediated signal transduction in the symbiont. The cAMP-mediated signal transduction is defined as a series of molecular signals in which a cell uses cyclic AMP to convert an extracellular signal into a response. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75206	positive regulation by host of symbiont cAMP-mediated signal transduction	P	Any process in which the host organism activates, maintains or increases the frequency, rate or extent of cAMP-mediated signal transduction in the symbiont organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75207	negative regulation by host of symbiont cAMP-mediated signal transduction	P	Any process in which the host organism stops, prevents, or reduces the frequency, rate or extent of cAMP-mediated signal transduction in the symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75208	modulation by symbiont of host cAMP-mediated signal transduction	P	Any process in which the symbiont modulates the frequency, rate or extent of cAMP-mediated signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75209	positive regulation by symbiont of host cAMP-mediated signal transduction	P	Any process in which the symbiont activates, maintains or increases the frequency, rate or extent of cAMP-mediated signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75210	negative regulation by symbiont of host cAMP-mediated signal transduction	P	Any process in which the symbiont organism stops, prevents, or reduces the frequency, rate or extent of cAMP-mediated signal transduction in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75211	regulation of transmembrane receptor-mediated cAMP signaling in response to host	P	Any process in which the symbiont organism modulates the frequency, rate or extent of its transmembrane receptor-mediated cAMP signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75212	positive regulation of transmembrane receptor-mediated cAMP signal transduction in response to host	P	Any process in which the symbiont organism activates, maintains or increases the frequency, rate or extent of its transmembrane receptor-mediated cAMP signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75213	negative regulation of transmembrane receptor-mediated cAMP signal transduction in response to host	P	Any process in which the symbiont organism stops, prevents, or reduces the frequency, rate or extent of its symbiont transmembrane receptor-mediated cAMP signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75214	spore encystment on host	P	The physiological, developmental and morphological changes that occur in a symbiont spore during the process of its encystment. Encystment means to enter a state of essentially suspended animation in which the spore is protected by an outer coating and remains immobile and inactive until favorable conditions for growth occur again. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75215	modulation of spore encystment on host	P	Any process that modulates the frequency, rate or extent of spore encystment on host. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75216	positive regulation of spore encystment on host	P	Any process that activates, maintains or increases the frequency, rate or extent of spore encystment on host. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75217	negative regulation of spore encystment on host	P	Any process that stops, prevents, or reduces the frequency, rate or extent of spore encystment on host. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75218	zoospore encystment on host	P	The physiological, developmental and morphological changes that occur in a symbiont zoospore during the process of its encystment. Encystment means to enter a state of essentially suspended animation in which the spore is protected by an outer coating and remains immobile and inactive until favorable conditions for growth occur again. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75219	modulation of zoospore encystment on host	P	Any process that modulates the frequency, rate or extent of zoospore encystment on host. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75220	positive regulation of zoospore encystment on host	P	Any process that activates, maintains or increases the frequency, rate or extent of zoospore encystment on host. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75221	negative regulation of zoospore encystment on host	P	Any process that stops, prevents, or reduces the frequency, rate or extent of zoospore encystment on host. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75222	sporangium germination on or near host	P	The physiological, developmental and morphological changes that occur in a symbiont sporangium following release from dormancy up to the earliest signs of growth occurring on or near its host organism. A sporangium is a structure producing and containing spores. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75223	modulation of sporangium germination on or near host	P	Any process that modulates the frequency, rate or extent of sporangium germination. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75224	positive regulation of sporangium germination on or near host	P	Any process that activates, maintains or increases the frequency, rate or extent of sporangium germination on or near host. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75225	negative regulation of sporangium germination on or near host	P	Any process that stops, prevents, or reduces the frequency, rate or extent of sporangium germination on or near host. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75226	encysted zoospore germination on or near host	P	The physiological, developmental and morphological changes that occur in the symbiont encysted zoospore, which is on or near its host organism and germinates by developing a germ tube that may penetrate the host directly or indirectly through an appresorium. An encysted zoospore is a zoospore which has shed its flagellum and whose membrane has fused to form a walled cyst. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75227	modulation of encysted zoospore germination on or near host	P	Any process that modulates the frequency, rate or extent of encysted zoospore germination on or near host. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75228	positive regulation of encysted zoospore germination on or near host	P	Any process that activates, maintains or increases the frequency, rate or extent of encysted zoospore germination on or near host. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75229	negative regulation of encysted zoospore germination on or near host	P	Any process that stops, prevents, or reduces the frequency, rate or extent of encysted zoospore germination on or near host. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75230	spore movement on or near host	P	Any process involved in the directed movement of a motile spore on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75231	modulation of spore movement on or near host	P	Any process that modulates the frequency, rate or extent of spore movement on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75232	positive regulation of spore movement on or near host	P	Any process that activates, maintains or increases the frequency, rate or extent of spore movement on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75233	negative regulation of spore movement on or near host	P	Any process that stops, prevents, or reduces the frequency, rate or extent of spore movement on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75234	zoospore movement on or near host	P	Any process involved in the directed movement of a zoospore on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75235	modulation of zoospore movement on or near host	P	Any process that modulates the frequency, rate or extent of zoospore movement on or near host. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75236	positive regulation of zoospore movement on or near host	P	Any process that activates, maintains or increases the frequency, rate or extent of zoospore movement on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75237	negative regulation of zoospore movement on or near host	P	Any process that stops, prevents, or reduces the frequency, rate or extent of zoospore movement on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75238	maintenance of symbiont tolerance to host pH environment	P	Any process that contributes to the maintenance of a physiologic state in which the symbiont immune system does not react destructively against pH environment of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75239	zoospore formation	P	The process in which a diploid cell undergoes meiosis, and the meiotic products acquire specialized features of asexual motile mononucleate flagellated spores called zoospores.
75240	regulation of zoospore formation	P	Any process that modulates the frequency, rate or extent of zoospore formation, a process in which a diploid cell undergoes meiosis, and the meiotic products acquire specialized features of asexual motile mononucleate flagellated spores called zoospores.
75241	positive regulation of zoospore formation	P	Any process that activates, maintains or increases the frequency, rate or extent of zoospore formation, a process in which a diploid cell undergoes meiosis, and the meiotic products acquire specialized features of asexual motile mononucleate flagellated spores called zoospores.
75242	negative regulation of zoospore formation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of zoospore formation, a process in which a diploid cell undergoes meiosis, and the meiotic products acquire specialized features of asexual motile mononucleate flagellated spores called zoospores.
75243	oospore formation	P	The process in which male and female gametangia develop and fuse to form an oospore, a thick-walled resting spore of oomycetes.
75244	regulation of oospore formation	P	Any process that modulates the frequency, rate or extent of oospore formation, a process in which male and female gametangia develop and fuse to form a thick-walled resting spore of oomycetes.
75245	positive regulation of oospore formation	P	Any process that activates, maintains or increases the frequency, rate or extent of oospore formation, a process in which male and female gametangia develop and fuse to form a thick-walled resting spore of oomycetes.
75246	negative regulation of oospore formation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of oospore formation, a process in which male and female gametangia develop and fuse to form a thick-walled resting spore of oomycetes.
75247	aeciospore formation	P	The process in which a dikaryotic spore of typically a rust fungus is produced in an aecium; in heteroecious rusts, the aeciospore is a spore stage that infects the alternate host.
75248	regulation of aeciospore formation	P	Any process that modulates the frequency, rate or extent of aeciospore formation, a process in which a dikaryotic spore of typically a rust fungus is produced in an aecium.
75249	positive regulation of aeciospore formation	P	Any process that activates, maintains or increases the frequency, rate or extent of aeciospore formation, a process in which a dikaryotic spore of typically a rust fungus is produced in an aecium.
75250	negative regulation of aeciospore formation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of aeciospore formation, a process in which a dikaryotic spore of typically a rust fungus is produced in an aecium.
75251	uredospore formation	P	The process which specific outcome is the formation of an asexual, dikaryotic, often rusty-colored spore, produced in a structure called a uredinium; mostly found in the rust fungus.
75252	regulation of uredospore formation	P	Any process that modulates the frequency, rate or extent of uredospore formation, a process in which an asexual, dikaryotic, often rusty-colored spore, is formed in a structure called a uredinium.
75253	positive regulation of uredospore formation	P	Any process that activates, maintains or increases the frequency, rate or extent of uredospore formation, a process in which an asexual, dikaryotic, often rusty-colored spore, is formed in a structure called a uredinium.
75254	negative regulation of uredospore formation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of uredospore formation, a process in which an asexual, dikaryotic, often rusty-colored spore, is formed in a structure called a uredinium.
75255	teliospore formation	P	The set of processes leading to the formation of a thick-walled resting or over-wintering spore produced by the rust fungi (Uredinales) and smut fungi (Ustilaginales) in which karyogamy occurs.
75256	regulation of teliospore formation	P	Any process that modulates the frequency, rate or extent of teliospore formation, which is the formation of a thick-walled resting or over-wintering spore produced by the rust fungi (Uredinales) and smut fungi (Ustilaginales) in which karyogamy occurs.
75257	positive regulation of teliospore formation	P	Any process that activates, maintains or increases the frequency, rate or extent of teliospore formation, which is the formation of a thick-walled resting or overwintering spore produced by the rust fungi (Uredinales) and smut fungi (Ustilaginales) in which karyogamy occurs.
75258	negative regulation of teliospore formation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of teliospore formation, which is the formation of a thick-walled resting or overwintering spore produced by the rust fungi (Uredinales) and smut fungi (Ustilaginales) in which karyogamy occurs.
75259	spore-bearing structure development	P	The process whose specific outcome is the progression of a spore-bearing structure over time, from its formation to the mature structure. A spore-bearing structure is an anatomical structure that produces new spores.
75260	regulation of spore-bearing organ development	P	Any process that modulates the frequency, rate or extent of spore-bearing organ development, a process in which hyphae grow into special aggregates called fruiting bodies that produce new spores.
75261	positive regulation of spore-bearing organ development	P	Any process that activates, maintains or increases the frequency, rate or extent of spore-bearing organ development, a process in which hyphae grow into special aggregates called fruiting bodies that produce new spores.
75262	negative regulation of spore-bearing organ development	P	Any process that stops, prevents, or reduces the frequency, rate or extent of spore-bearing organ development, a process in which hyphae grow into special aggregates called fruiting bodies that produce new spores.
75263	oogonium development	P	The process that leads to the development of an oogonium, a female gametangium of Oomycetes, containing one or more gametes.
75264	regulation of oogonium development	P	Any process that modulates the frequency, rate or extent of oogonium development, a process that leads to the formation of a female gametangium of oomycetes, containing one or more gametes.
75265	positive regulation of oogonium development	P	Any process that activates, maintains or increases the frequency, rate or extent of oogonium development, a process that leads to the formation of a female gametangium of oomycetes, containing one or more gametes.
75266	negative regulation of oogonium development	P	Any process that stops, prevents, or reduces the frequency, rate or extent of oogonium development, a process that leads to the formation of a female gametangium of oomycetes, containing one or more gametes.
75267	aecium development	P	The process in which a cup-like structure containing chains of aeciospores is formed. This is characteristic of the rust fungus and typically, the first dikaryotic spores (aeciospores) are produced in the aecium.
75268	regulation of aecium development	P	Any process that modulates the frequency, rate or extent of aecium development, a process in which a cuplike structure containing chains of aeciospores is formed.
75269	positive regulation of aecium development	P	Any process that activates, maintains or increases the frequency, rate or extent of aecium development, a process in which a cuplike structure containing chains of aeciospores is formed.
75270	negative regulation of aecium development	P	Any process that stops, prevents, or reduces the frequency, rate or extent of aecium development, a process in which a cuplike structure containing chains of aeciospores is formed.
75271	zygosporangium development	P	The process in which a fruiting body called zygosporangium is formed. A zygosporangium is a thick-walled structure in which spores are produced, and is characteristic of the Zygomycetes.
75272	regulation of zygosporangium development	P	Any process that modulates the frequency, rate or extent of zygosporangium development, a process in which a fruiting body called zygosporangium is formed.
75273	positive regulation of zygosporangium development	P	Any process that activates, maintains or increases the frequency, rate or extent of zygosporangium development, a process in which a fruiting body called zygosporangium is formed.
75274	negative regulation of zygosporangium development	P	Any process that stops, prevents, or reduces the frequency, rate or extent of zygosporangium development, a process in which a fruiting body called zygosporangium is formed.
75275	telium development	P	The process that leads to the development of a telium, which is a teliospore-bearing sorus of the rust fungi.
75276	regulation of telium development	P	Any process that modulates the frequency, rate or extent of telium development, a process that leads to the formation of a teliospore-bearing sorus of the rust fungi.
75277	positive regulation of telium development	P	Any process that activates, maintains or increases the frequency, rate or extent of telium development, a process that leads to the formation of a teliospore-bearing sorus of the rust fungi.
75278	negative regulation of telium development	P	Any process that stops, prevents, or reduces the frequency, rate or extent of telium development, a process that leads to the formation of a teliospore-bearing sorus of the rust fungi.
75279	uredinium development	P	The process that leads to the formation of a uredinium, a reddish, pustule-like structure formed by a rust fungus and consisting of uredospores.
75280	regulation of uredinium development	P	Any process that modulates the frequency, rate or extent of uredinium development, a process that leads to the formation of a reddish, pustule-like structure formed by a rust fungus and consisting of uredospores.
75281	positive regulation of uredinium development	P	Any process that activates, maintains or increases the frequency, rate or extent of uredinium development, a process that leads to the formation of a reddish, pustule-like structure formed by a rust fungus and consisting of uredospores.
75282	negative regulation of uredinium development	P	Any process that stops, prevents, or reduces the frequency, rate or extent of uredinium development, a process that leads to the formation of a reddish, pustule-like structure formed by a rust fungus and consisting of uredospores.
75283	sporulation resulting in formation of a multicellular or syncytial spore	P	The process whose specific outcome is the progression of a multicellular or syncytial spore via septations over time, from its initiation to the mature structure.
75284	asexual sporulation resulting in formation of a multicellular or syncytial spore	P	The formation of a multicellular or syncytial spore via septations derived from mitosis.
75285	sexual sporulation resulting in formation of a multicellular or syncytial spore	P	The formation of multicellular or syncytial spore via septations derived from meiosis. A multicellular or syncytial spore is a structure that can be used for dissemination, for survival of adverse conditions because of its heat and dessication resistance, and/or for reproduction.
75286	regulation of sporangiospore formation	P	Any process that modulates the frequency, rate or extent of sporangiospore formation, a process in which sporangiospores, a type of asexual spore found in fungi, are formed. Sporangiospores are formed within sac-like structure, the sporangium, following the division of the cytoplasm.
75287	positive regulation of sporangiospore formation	P	Any process that activates, maintains or increases the frequency, rate or extent of sporangiospore formation, a process in which sporangiospores, a type of asexual spore found in fungi, are formed. Sporangiospores are formed within sac-like structure, the sporangium, following the division of the cytoplasm.
75288	negative regulation of sporangiospore formation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of sporangiospore formation, a process in which sporangiospores, a type of asexual spore found in fungi, are formed. Sporangiospores are formed within sac-like structure, the sporangium, following the division of the cytoplasm.
75289	aplanospore formation	P	The process in which a nonmotile, asexual spore is formed within a cell in certain algae and fungi (commonly in the Phycomycetes), the wall of aplanospore is distinct from that of the parent cell.
75290	regulation of aplanospore formation	P	Any process that modulates the frequency, rate or extent of aplanospore formation, a process in which a nonmotile, asexual spore is formed within a cell in certain algae and fungi (commonly in the Phycomycetes), the wall of aplanospore is distinct from that of the parent cell.
75291	positive regulation of aplanospore formation	P	Any process that activates, maintains or increases the frequency, rate or extent of aplanospore formation, a process in which a nonmotile, asexual spore is formed within a cell in certain algae and fungi (commonly in the Phycomycetes), the wall of aplanospore is distinct from that of the parent cell.
75292	negative regulation of aplanospore formation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of aplanospore formation, a process in which a nonmotile, asexual spore is formed within a cell in certain algae and fungi (commonly in the Phycomycetes), the wall of aplanospore is distinct from that of the parent cell.
75293	response to host pH environment	P	Any process that results in a change in state or activity of the symbiont or its cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the pH conditions in or around its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75294	positive regulation by symbiont of entry into host	P	Any process that activates or increases the frequency, rate or extent to which it enters into the host organism, where the two organisms are in a symbiotic interaction.
75295	positive regulation by organism of entry into other organism involved in symbiotic interaction	P	Any process that activates or increases the frequency, rate or extent to which it enters into a second organism, where the two organisms are in a symbiotic interaction.
75296	positive regulation of ascospore formation	P	Any process that activates, maintains or increases the frequency, rate or extent of ascospore formation, a process in which a sexual spore, named ascospore, from Ascomycete fungi was produced inside an ascus.
75297	negative regulation of ascospore formation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of ascospore formation, a process in which a sexual spore, named ascospore, from Ascomycete fungi was produced inside an ascus.
75298	regulation of zygospore formation	P	Any process that modulates the frequency, rate or extent of zygospore formation, a process in which a thick-walled spore of some algae and fungi is formed by union of two similar sexual cells, usually serves as a resting spore, and produces the sporophytic phase.
75299	positive regulation of zygospore formation	P	Any process that activates, maintains or increases the frequency, rate or extent of frequency, rate or extent of zygospore formation, a process in which a thick-walled spore of some algae and fungi is formed by union of two similar sexual cells, usually serves as a resting spore, and produces the sporophytic phase.
75300	negative regulation of zygospore formation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of zygospore formation, a process in which a thick-walled spore of some algae and fungi is formed by union of two similar sexual cells, usually serves as a resting spore, and produces the sporophytic phase.
75302	regulation of basidiospore formation	P	Any process that modulates the frequency, rate or extent of basidiospore formation, a process in which a sexually produced fungal spore is formed on a basidium in the fungi Basidiomycetes.
75303	positive regulation of basidiospore formation	P	Any process that activates, maintains or increases the frequency, rate or extent of frequency, rate or extent of basidiospore formation, a process in which a sexually produced fungal spore is formed on a basidium in the fungi basidiomycetes.
75304	negative regulation of basidiospore formation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of basidiospore formation, a process in which a sexually produced fungal spore is formed on a basidium in the fungi basidiomycetes.
75306	regulation of conidium formation	P	Any process that modulates the frequency, rate or extent of conidium formation, a process of producing non-motile spores, called conidia, via mitotic asexual reproduction in higher fungi. Conidia are haploid cells genetically identical to their haploid parent. They are produced by conversion of hyphal elements, or are borne on sporogenous cells on or within specialized structures termed conidiophores, and participate in dispersal of the fungus.
75307	positive regulation of conidium formation	P	Any process that activates, maintains or increases the frequency, rate or extent of conidium formation, a process of producing non-motile spores, called conidia, via mitotic asexual reproduction in higher fungi. Conidia are haploid cells genetically identical to their haploid parent. They are produced by conversion of hyphal elements, or are borne on sporogenous cells on or within specialized structures termed conidiophores, and participate in dispersal of the fungus.
75308	negative regulation of conidium formation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of conidium formation, a process of producing non-motile spores, called conidia, via mitotic asexual reproduction in higher fungi. Conidia are haploid cells genetically identical to their haploid parent. They are produced by conversion of hyphal elements, or are borne on sporogenous cells on or within specialized structures termed conidiophores, and participate in dispersal of the fungus.
75310	regulation of sporangium development	P	Any process that modulates the frequency, rate or extent of sporangium development, a process that leads to the formation of sporangium, a single-celled or many-celled structure in which spores are produced, as in fungi, algae, mosses, and ferns, gymnosperms, angiosperms.
75311	positive regulation of sporangium development	P	Any process that activates, maintains or increases the frequency, rate or extent of sporangium development, a process that leads to the formation of sporangium, a single-celled or many-celled structure in which spores are produced, as in fungi, algae, mosses, and ferns, gymnosperms, angiosperms.
75312	negative regulation of sporangium development	P	Any process that stops, prevents, or reduces the frequency, rate or extent of sporangium development, a process that leads to the formation of sporangium, a single-celled or many-celled structure in which spores are produced, as in fungi, algae, mosses, and ferns, gymnosperms, angiosperms.
75313	basidium development	P	The process that leads to the development of basidium, a small, specialized club-shaped structure typically bearing four basidiospores at the tips of minute projections. The basidium is unique to Basidiomycetes and distinguishes them from other kinds of fungi.
75314	regulation of basidium development	P	Any process that modulates the frequency, rate or extent of basidium development, a process that leads to the formation of a basidium, a small, specialized club-shaped structure typically bearing four basidiospores at the tips of minute projections. The basidium is unique to Basidiomycetes and distinguishes them from other kinds of fungi.
75315	positive regulation of basidium development	P	Any process that activates, maintains or increases the frequency, rate or extent of basidium development, a process that leads to the formation of basidium, a small, specialized club-shaped structure typically bearing four basidiospores at the tips of minute projections. The basidium is unique to basidiomycetes and distinguishes them from other kinds of fungi.
75316	negative regulation of basidium development	P	Any process that stops, prevents, or reduces the frequency, rate or extent of basidium development, a process that leads to the formation of basidium, a small, specialized club-shaped structure typically bearing four basidiospores at the tips of minute projections. The basidium is unique to basidiomycetes and distinguishes them from other kinds of fungi.
75317	ascus development	P	The process that leads to the development of ascus, a sac-like structure produced by fungi of the phylum Ascomycota (sac fungi) in which sexually produced spores (ascospores), usually four or eight in number, are formed.
75318	regulation of ascus development	P	Any process that modulates the frequency, rate or extent of ascus development, a process that leads to the formation of basidium, a sac-like structure produced by fungi of the phylum Ascomycota (sac fungi) in which sexually produced spores (ascospores), usually four or eight in number, are formed.
75319	positive regulation of ascus development	P	Any process that activates, maintains or increases the frequency, rate or extent of ascus development, a saclike structure produced by fungi of the phylum Ascomycota (sac fungi) in which sexually produced spores (ascospores), usually four or eight in number, are formed.
75320	negative regulation of ascus development	P	Any process that stops, prevents, or reduces the frequency, rate or extent of ascus development, a saclike structure produced by fungi of the phylum Ascomycota (sac fungi) in which sexually produced spores (ascospores), usually four or eight in number, are formed.
75321	oomycete sporangium development	P	The process that leads to the development of an oomycete sporangium, a single-celled or many-celled structure that germinates directly to form an infection hypha or differentiates, through specialized cleavage vesicles, into between 10 and 30 zoospores, which are laterally flagellated.
75322	regulation of oomycete sporangium development	P	Any process that modulates the frequency, rate or extent of oomycete sporangium development, a process that leads to the formation of oomycete sporangium, a single-celled or many-celled structure that germinates directly to form an infection hypha or differentiate, through specialized cleavage vesicles, into between 10 and 30 zoospores, which is laterally flagellated.
75323	positive regulation of oomycete sporangium development	P	Any process that activates, maintains or increases the frequency, rate or extent of oomycete sporangium development, a process that leads to the formation of oomycete sporangium, a single-celled or many-celled structure that germinates directly to form an infection hypha or differentiate, through specialized cleavage vesicles, into between 10 and 30 zoospores, which is laterally flagellated.
75324	negative regulation of oomycete sporangium development	P	Any process that stops, prevents, or reduces the frequency, rate or extent of oomycete sporangium development, a process that leads to the formation of oomycete sporangium, a single-celled or many-celled structure that germinates directly to form an infection hypha or differentiate, through specialized cleavage vesicles, into between 10 and 30 zoospores, which is laterally flagellated.
75325	spore dispersal on or near host	P	Any process in which a symbiont disseminates its spores, on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75326	active spore dispersal on or near host	P	Any active process in which a symbiont disseminates its spores, on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75327	passive spore dispersal on or near host	P	Any passive process in which a symbiont disseminates its spores, on or near its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75328	formation by symbiont of arbuscule for nutrient acquisition from host	P	The assembly by an organism of an arbuscule, a fine, tree-like hyphal structure projected into the host cell for the purpose of obtaining nutrients from its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75329	regulation of arbuscule formation for nutrient acquisition from host	P	Any process that modulates the frequency, rate or extent of symbiont arbuscule formation for nutrient acquisition from host. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75330	positive regulation of arbuscule formation for nutrient acquisition from host	P	Any process that activates or increases the frequency, rate or extent of symbiont arbuscule formation for nutrient acquisition from host. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75331	negative regulation of arbuscule formation for nutrient acquisition from host	P	Any process that stops, prevents, or reduces the frequency, rate or extent of symbiont arbuscule formation for nutrient acquisition from host. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75332	modulation by host of symbiont adenylate cyclase-mediated signal transduction	P	Any process in which the host organism modulates the frequency, rate or extent of adenylate cyclase-mediated signal transduction in the symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75333	positive regulation by host of symbiont adenylate cyclase-mediated signal transduction	P	Any process in which the host organism activates, maintains or increases the frequency, rate or extent of adenylate cyclase-mediated signal transduction in the symbiont organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75334	modulation of symbiont adenylate cyclase-mediated signal transduction in response to host	P	Any process in which the symbiont organism modulates the frequency, rate or extent of its adenylate cyclase-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75335	positive regulation of symbiont adenylate cyclase-mediated signal transduction in response to host	P	Any process in which the symbiont organism activates, maintains or increases the frequency, rate or extent of its adenylate cyclase-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75336	negative regulation of symbiont adenylate cyclase-mediated signal transduction in response to host	P	Any process in which the symbiont organism stops, prevents, or reduces the frequency, rate or extent of its symbiont adenylate cyclase-mediated signal transduction as a result of detecting molecules of its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75341	host cell PML body	C	A nuclear body that reacts against SP100 auto-antibodies (PML = promyelocytic leukemia) located within a cell of a host organism.
75342	disruption by symbiont of host cell PML body	P	The breakdown, by the symbiont, of a PML body within a host cell. A PML body is a nuclear body that reacts against SP100 auto-antibodies (PML = promyelocytic leukemia). The host is defined as the larger of the organisms involved in a symbiotic interaction.
75343	modulation by symbiont of abscisic acid levels in host	P	The alteration by an organism of the levels of abscisic acid in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75344	modulation by symbiont of host protein levels	P	The alteration by an organism of protein levels in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75345	modification by symbiont of host protein	P	The covalent alteration by an organism of one or more amino acids occurring in proteins, peptides and nascent polypeptides (co-translational, post-translational modifications) of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75346	modification by symbiont of host protein by ubiquitination	P	The process in which an organism adds one or more ubiquitin groups to a protein of the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
75502	endosome membrane permeabilization involved in viral entry into host cell	P	Induction of endosome membrane permeabilization triggered by an interaction between the host membrane and a membrane-penetration protein associated with the capsid. Occurs after internalization of the virus through the endosomal pathway, and results in delivery of the virus contents into the host cell cytoplasm.
75503	fusion of virus membrane with host macropinosome membrane	P	Fusion of a viral membrane with a host macropinosome membrane, that occurs after internalization of the virus through the endosomal pathway, and results in release of the viral contents into the host cell cytoplasm.
75504	macropinosomal membrane permeabilization involved in viral entry into host cell	P	Induction of macropinosome membrane permeabilization triggered by an interaction between the host membrane and a membrane-penetration protein associated with the capsid. Occurs after internalization of the virus in a macropinosome, and results in release of the viral contents from the macropinosome into the host cell cytoplasm.
75505	entry of intact viral capsid into host nucleus through nuclear pore complex	P	Viral penetration into the host nucleus where a viral capsid passes intact through the host nuclear pore complex (NPC).
75506	entry of viral genome into host nucleus through nuclear pore complex via importin	P	Viral penetration into the host nucleus where the viral genome passes through the nuclear pore complex (NPC) using the cellular importin transport machinery.
75507	entry of viral genome into host nucleus via docking of viral capsid to the nuclear pore complex and injection of viral genome	P	Viral penetration into the host nucleus where the where a viral capsid docks on the cytoplasmic side of the nuclear pore complex (NPC) and ejects the viral genome through the pore into the nucleoplasm.
75508	entry of viral genome into host nucleus via retainment of capsid in nuclear pore complex and release of genome into nucleoplasm	P	Viral penetration into the host nucleus where a viral capsid enters the host nuclear pore complex (NPC) but remains attached to the pore on the nuclear side. The capsid then disassembles, releasing the viral genome into the nucleoplasm.
75509	endocytosis involved in viral entry into host cell	P	Any endocytosis that is involved in the uptake of a virus into a host cell.
75510	macropinocytosis involved in viral entry into host cell	P	Any macropinocytosis that is involved in the uptake of a virus into a host cell.
75511	macropinosome lysis involved in viral entry into host cell	P	Viral-induced lysis of the macropinosome involved in the uptake of a virus into a host cell. Occurs after internalization of the virus in a macropinosome, and results in the release of viral contents from the macropinosome into the host cell cytoplasm.
75512	clathrin-dependent endocytosis of virus by host cell	P	Any clathrin-mediated endocytosis that is involved in the uptake of a virus into a host cell. Begins by invagination of a specific region of the host cell plasma membrane around the bound virus to form a clathrin-coated pit, which then pinches off to form a clathrin-coated endocytic vesicle containing the virus.
75513	caveolin-mediated endocytosis of virus by host cell	P	Any caveolin-mediated endocytosis that is involved in the uptake of a virus into a host cell. Begins when material is taken up into plasma membrane caveolae - specialized lipid rafts that form 50-70 nm flask-shaped invaginations of the plasma membrane - which then pinch off to form endocytic caveolar carriers containing the virus.
75514	endosome lysis involved in viral entry into host cell	P	Viral-induced lysis of the endosome involved in uptake of a virus into a host cell. Occurs after internalization of the virus through the endosomal pathway, and results in release of the viral contents from the endosome into the host cell cytoplasm.
75519	microtubule-dependent intracellular transport of viral material	P	The directed movement of the viral genome or viral particle within the host cell cytoplasm along host microtubules. Microtubule-dependent transport involves motor proteins like dynein and kinesin and is mostly used by viruses that target their genomes to the nucleus.
75520	actin-dependent intracellular transport of virus	P	The directed movement of a virus, or part of a virus, within the host cell cytoplasm via the host's actin filaments. Actin-dependent transport is induced by viral proteins that interact with actin and/or host cell motor proteins like myosins or that promotes actin polymerization/depolymerization reactions.
75521	microtubule-dependent intracellular transport of viral material towards nucleus	P	The directed movement of a virus, or part of a virus, towards the host cell nucleus using host microtubules.
75522	IRES-dependent viral translational initiation	P	Process by which viral mRNA translation is initiated, where a domain in the 5' untranslated region (UTR) of the viral mRNA called an internal ribosome entry site (IRES) binds the host 43S preinitiation complex, circumventing regular cap-dependent translation initiation.
75523	viral translational frameshifting	P	A process which occurs during viral translation, which involves a translational recoding mechanism called programmed ribosomal frameshifting. This causes the ribosome to alter its reading of the mRNA to an a different open reading frame to produce alternate viral proteins.
75524	ribosomal skipping	P	A translation process in which a specific viral peptide prevents the ribosome from covalently linking a new inserted amino acid, and lets it continue translation, thereby cleaving the nascent protein while allowing translation to continue.
75525	viral translational termination-reinitiation	P	A process which occurs as part of viral mRNA translation which allows expression of a downstream open reading frame (ORF) in a dicistronic mRNA. In this process, ribosomes translate the upstream ORF but following termination, a proportion of 40S subunits remain tethered to the mRNA and go on to re-initiate translation at the start codon of the downstream ORF.
75526	cap snatching	P	A transcription initiation process during which a nucleotide sequence between 10 and 20 nucleotides in size is cleaved from the 5' end of host mRNAs by a viral RNA-dependent polymerase. The capped leader sequence obtained is subsequently used to prime transcription on the viral genome, which ultimately leads to the synthesis of capped, translatable viral mRNAs.
75527	viral RNA editing	P	The process by which bases in viral mRNA are chemically altered during viral transcription. This is usually the incorporation of 1 - 6 additional nucleotides, which shifts the reading frame, allowing the generation of different protein products or through a specific nucleotide change that eliminates the termination codon.
75528	modulation by virus of host immune response	P	The process in which a virus effects a change in the host immune response.
75529	establishment of latency as a circular episome	P	A process by which a virus establishes a latent state within its host as an episome, where the viral genome remains silent in the cytoplasm or nucleus as a circular structure.
75530	establishment of latency as a linear episome	P	A process by which a virus establishes a latent state within its host as an episome, where the viral genome remains silent in the cytoplasm or nucleus as linear structure.
75606	transport of viral material towards nucleus	P	The directed movement of a virus, or part of a virus, towards the host cell nucleus. The process begins after viral entry, and ends when the viral material is at the nuclear membrane.
75713	establishment of integrated proviral latency	P	A process by which the virus integrates into the host genome and establishes as a stable provirus or prophage.
75720	establishment of episomal latency	P	A process by which a virus establishes a latent state within its host as an episome, where the viral genome remains silent in the cytoplasm or nucleus as a distinct genetic entity.
75732	viral penetration into host nucleus	P	The crossing by the virus of the host nuclear membrane, either as naked viral genome or for small viruses as an intact capsid.
75733	intracellular transport of virus	P	The directed movement of a virus, or part of a virus, within the host cell.
80001	mucilage extrusion from seed coat	P	The process in which seed mucilage expands through hydration and breaks the outer cell wall that encapsulates the whole seed upon imbibition. Mucilage, mainly composed of pectins, is formed during seed development and deposited into the apoplast underneath the outer wall of the seed coat.
80002	UDP-glucose:4-aminobenzoate acylglucosyltransferase activity	F	Catalysis of the reaction: 4-aminobenzoate + UDP-glucose = p-aminobenzoate-beta-D-glucopyranosyl ester + UDP.
80003	thalianol metabolic process	P	The chemical reactions and pathways involving the triterpene thalianol.
80004	thalian-diol desaturase activity	F	Catalysis of the reaction: a thalian-diol = a desaturated thalian-diol. This reaction is the introduction of a double bond to a thalian-diol molecule at carbon 15.
80005	photosystem stoichiometry adjustment	P	Adjustment of Photosystem I/Photosystem II ratio in response to light conditions. The function of photosystem stoichiometry adjustment is to compensate for any deficiency in energy conversion at either photosystem I or photosystem II by increasing the quantity the photosystem that will otherwise become the rate-limiting to overall photosynthesis.
80006	internode patterning	P	Determines the spacing between two shoot nodes. A shoot node is the region of the shoot where the spikelet, flower, floret, branch, bud and/or leaves are attached.
80007	S-nitrosoglutathione reductase activity	F	Catalysis of the reaction: glutathione N-hydroxysulfenamide + NADH + H+ = S-nitrosoglutathione + NAD+.
80008	Cul4-RING E3 ubiquitin ligase complex	C	A ubiquitin ligase complex in which a cullin from the Cul4 family and a RING domain protein form the catalytic core; substrate specificity is conferred by an adaptor protein.
80009	mRNA methylation	P	The posttranscriptional addition of methyl groups to specific residues in an mRNA molecule.
80011	baruol synthase activity	F	Catalysis of the reaction: (S)-2,3-epoxysqualene = baruol. Baruol is also known as D:B-Friedo-Baccharan-5,21-dien-3-ol.
80012	trihydroxyferuloyl spermidine O-methyltransferase activity	F	Catalysis of the reaction: trihydroxyferuloyl spermidine + S-adenosyl-L-methionine = dihydroxyferuloyl-sinapoyl spermidine + S-adenosyl-L-homocysteine + H+.
80013	(E,E)-geranyllinalool synthase activity	F	Catalysis of the reaction: all-trans-geranyl-geranyl diphosphate + H2O = (E,E)-geranyllinalool + diphosphate.
80014	thalianol hydroxylase activity	F	Catalysis of the reaction: a thalianol = a thalian-diol. This reaction is the addition of a hydroxyl group to thalianol ((13R,14R,17E)-podioda-8,17,21-trien-3beta-ol) to create a thalian-diol ((13R,14R,17E)-podioda-8,17,21-trien-3beta,X-diol), where the hydroxyl group may be attached at one of several different available carbons in ring B or C of thalianol, indicated by the X.
80015	sabinene synthase activity	F	Catalysis of the reaction: geranyl diphosphate = sabinene + diphosphate.
80016	(-)-E-beta-caryophyllene synthase activity	F	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = (-)-E-beta-caryophyllene + diphosphate.
80017	alpha-humulene synthase activity	F	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate = alpha-humulene + diphosphate.
80018	anthocyanin 5-O-glucosyltransferase activity	F	Catalysis of the reaction: an anthocyanin + UDP-D-glucose = an anthocyanin-5-O-glucoside + UDP.
80019	fatty-acyl-CoA reductase (alcohol-forming) activity	F	Catalysis of the reaction: a very long chain fatty acyl-CoA + NADPH + H+ = a very long chain primary alcohol + NADP+ + CoA.
80020	regulation of coenzyme A biosynthetic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving coenzyme A.
80021	response to benzoic acid	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a benzoic acid stimulus.
80022	primary root development	P	The process whose specific outcome is the progression of the primary root over time, from its formation to the mature structure. The primary root develops directly from the embryonic radicle.
80023	3R-hydroxyacyl-CoA dehydratase activity	F	Catalysis of the reaction: 3R-hydroxyacyl-CoA = 2E-enoyl-CoA + H2O.
80024	indolebutyric acid metabolic process	P	The chemical reactions and pathways involving indolebutyric acid, a compound that serves as an active or storage form of the hormone indole-3-acetic acid (an auxin) in many plants.
80025	phosphatidylinositol-3,5-bisphosphate binding	F	Interacting selectively and non-covalently with phosphatidylinositol-3,5-bisphosphate, a derivative of phosphatidylinositol in which the inositol ring is phosphorylated at the 3' and 5' positions.
80026	response to indolebutyric acid	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an indolebutyric acid stimulus.
80027	response to herbivore	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a herbivore.
80028	nitrile biosynthetic process	P	The chemical reactions and pathways resulting in the formation of a nitrile, an organic compound containing trivalent nitrogen attached to one carbon atom.
80029	cellular response to boron-containing substance levels	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus reflecting the presence, absence, or concentration of boron-containing substances.
80030	methyl indole-3-acetate esterase activity	F	Catalysis of the reaction: methyl indole-3-acetate + H2O = indole-3-acetate + methanol + H+.
80031	methyl salicylate esterase activity	F	Catalysis of the reaction: methyl salicylate + H2O = salicylic acid + methanol + H+.
80032	methyl jasmonate esterase activity	F	Catalysis of the reaction: a methyl jasmonate + H2O = a jasmonic acid + methanol.
80033	response to nitrite	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrite stimulus.
80034	host response to induction by symbiont of tumor, nodule or growth in host	P	Any process that results in a change in the state or activity of a host cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the formation of an abnormal mass of cells in the host organism, induced by a symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction.
80035	2-hydroxy-but-3-enyl glucosinolate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of progoitrin, a 2-hydroxy-but-3-enyl glucosinolate. Glucosinolates are substituted thioglucosides found in rapeseed products and related cruciferae, and progoitrin has been implicated in causing goiters in mammals and bitter taste in cruciferous vegetables.
80036	regulation of cytokinin-activated signaling pathway	P	Any process that modulates the frequency, rate or extent of cytokinin signaling.
80037	negative regulation of cytokinin-activated signaling pathway	P	Any process that stops, prevents, or reduces the frequency, rate or extent of cytokinin signaling.
80038	positive regulation of cytokinin-activated signaling pathway	P	Any process that activates or increases the frequency, rate or extent of cytokinin signaling.
80039	xyloglucan endotransglucosylase activity	F	Catalysis of the hydrolysis of a beta-(1,4) bond in the backbone of a xyloglucan and transfers the xyloglucanyl segment on to O-4 of the non-reducing terminal glucose residue of a xyloglucan or an oligosaccharide of xyloglucan.
80040	positive regulation of cellular response to phosphate starvation	P	Any process that activates or increases the frequency, rate or extent of cellular response to phosphate starvation.
80041	ADP-ribose pyrophosphohydrolase activity	F	Catalysis of the reaction: ADP-ribose + H2O = AMP + ribose-1-phosphate.
80042	ADP-glucose pyrophosphohydrolase activity	F	Catalysis of the reaction: ADP-glucose + H2O = AMP + glucose-1-phosphate.
80043	quercetin 3-O-glucosyltransferase activity	F	Catalysis of the transfer of a glucosyl group from UDP-glucose to the 3-hydroxy group of a quercetin molecule.
80044	quercetin 7-O-glucosyltransferase activity	F	Catalysis of the transfer of a glucosyl group from UDP-glucose to the 7-hydroxy group of a quercetin molecule.
80045	quercetin 3'-O-glucosyltransferase activity	F	Catalysis of the transfer of a glucosyl group from UDP-glucose to the 3'-hydroxy group of a quercetin molecule.
80046	quercetin 4'-O-glucosyltransferase activity	F	Catalysis of the transfer of a glucosyl group from UDP-glucose to the 4'-hydroxy group of a quercetin molecule.
80047	GDP-L-galactose phosphorylase activity	F	Catalysis of the reaction: GDP-L-galactose + phosphate = L-galactose-1-P + GDP.
80048	GDP-D-glucose phosphorylase activity	F	Catalysis of the reaction: GDP-D-glucose + phosphate = D-glucose-1-P + GDP.
80049	L-gulono-1,4-lactone dehydrogenase activity	F	Catalysis of the reaction: L-gulono-1,4-lactone + 2 ferricytochrome c = L-ascorbate + 2 ferrocytochrome c.
80050	regulation of seed development	P	Any process that modulates the frequency, rate or extent of seed development.
80051	cutin transport	P	The directed movement of cutin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Cutin, which consists of C16-18 fatty acids, is the major component of the cuticle that covers the plant surface.
80052	response to histidine	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a histidine stimulus.
80053	response to phenylalanine	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a phenylalanine stimulus.
80054	low-affinity nitrate transmembrane transporter activity	F	Enables the transfer of nitrate ions (NO3-) from one side of a membrane to the other. In low-affinity transport the transporter is able to bind the solute only if it is present at very high concentrations.
80055	low-affinity nitrate transport	P	The directed movement of nitrate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. In low-affinity transport the transporter is able to bind the solute only if it is present at very high concentrations.
80056	petal vascular tissue pattern formation	P	Vascular tissue pattern formation as it occurs in the petal of vascular plants.
80057	sepal vascular tissue pattern formation	P	Vascular tissue pattern formation as it occurs in the sepal of vascular plants.
80058	protein deglutathionylation	P	The protein modification process in which a glutathione molecule is removed from a protein amino acid by breaking a disulfide linkage.
80059	flavonol 3-O-arabinosyltransferase activity	F	Catalysis of the reaction: UDP-arabinose + a flavonol = UDP + a flavonol 3-O-D-arabinoside.
80060	integument development	P	The process whose specific outcome is the progression of the integument over time, from its formation to the mature structure. Integument is one of the layers of tissue that usually covers the ovule, enveloping the nucellus and forming the micropyle at the apex.
80061	indole-3-acetonitrile nitrilase activity	F	Catalysis of the reaction: indole-3-acetonitrile + 2 H2O = indole-3-acetic acid + NH3.
80062	cytokinin 9-beta-glucosyltransferase activity	F	Catalysis of the reaction: 6-alkylaminopurine + UDP-D-glucose = 6-alkylamino-9-beta-D-glucosylpurine + H+ + UDP. This reaction is an N-glucosylation event.
80064	4,4-dimethyl-9beta,19-cyclopropylsterol oxidation	P	A lipid oxidation process proceeding through a series of three successive monooxygenations of the alpha methyl group on the C4 carbon (CH3 to CH2OH to CHO to COOH) and resulting in this overall reaction: 4,4-dimethyl-9beta,19-cyclopropylsterol + 3 NADPH + 3 H+ + 3 O2 = 4-alpha-carboxy, 4-beta-methyl-9beta,19-cyclopropylsterol + 3 NADP+ + 3 H2O.
80065	4-alpha-methyl-delta7-sterol oxidation	P	A lipid oxidation process proceeding through a series of three successive monooxygenations of the alpha methyl group on the C4 carbon (CH3 to CH2OH to CHO to COOH) and resulting in this overall reaction: 4-alpha-methyl-delta7-sterol + 3 NADPH + 3 H+ + 3 O2 = 4-alpha-carboxy,delta7-sterol + 3 NADP+ + 3 H2O.
80066	3-methylthiopropyl-desulfoglucosinolate sulfotransferase activity	F	Catalysis of the reaction: 3-methylthiopropyl-desulfoglucosinolate + 3'-phosphoadenosine 5'-phosphosulfate = 3-methylthiopropyl-glucosinolate + adenosine 3',5'-bisphosphate.
80067	4-methylthiobutyl-desulfoglucosinolate sulfotransferase activity	F	Catalysis of the reaction: 4-methylthiobutyl-desulfoglucosinolate + 3'-phosphoadenosine 5'-phosphosulfate = 4-methylthiobutyl-glucosinolate + adenosine 3',5'-bisphosphate.
80068	5-methylthiopentyl-desulfoglucosinolate sulfotransferase activity	F	Catalysis of the reaction: 5-methylthiopentyl-desulfoglucosinolate + 3'-phosphoadenosine 5'-phosphosulfate = 5-methylthiopentyl-glucosinolate + adenosine 3',5'-bisphosphate.
80069	7-methylthioheptyl-desulfoglucosinolate sulfotransferase activity	F	Catalysis of the reaction: 7-methylthioheptyl-desulfoglucosinolate + 3'-phosphoadenosine 5'-phosphosulfate = 7-methylthioheptyl-glucosinolate + adenosine 3',5'-bisphosphate.
80070	8-methylthiooctyl-desulfoglucosinolate sulfotransferase activity	F	Catalysis of the reaction: 8-methylthiooctyl-desulfoglucosinolate + 3'-phosphoadenosine 5'-phosphosulfate = 8-methylthiooctyl-glucosinolate + adenosine 3',5'-bisphosphate.
80071	indol-3-yl-methyl-desulfoglucosinolate sulfotransferase activity	F	Catalysis of the reaction: indol-3-yl-methyl-desulfoglucosinolate + 3'-phosphoadenosine 5'-phosphosulfate = indol-3-yl-methyl-glucosinolate + adenosine 3',5'-bisphosphate.
80072	spermidine:sinapoyl CoA N-acyltransferase activity	F	Catalysis of the transfer of a sinapoyl group to a nitrogen atom on the spermidine molecule.
80073	spermidine:coumaroyl CoA N-acyltransferase activity	F	Catalysis of the transfer of a coumaroyl group to a nitrogen atom on the spermidine molecule.
80074	spermidine:caffeoyl CoA N-acyltransferase activity	F	Catalysis of the transfer of a caffeoyl group to a nitrogen atom on the spermidine molecule.
80075	spermidine:feruloyl CoA N-acyltransferase activity	F	Catalysis of the transfer of a feruloyl group to a nitrogen atom on the spermidine molecule.
80076	caffeoyl CoA:S-adenosyl-L-methionine O-methyltransferase activity	F	Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to the oxygen atom of a caffeoyl CoA molecule.
80077	trihydroxyferuloyl spermidine:S-adenosyl-L-methionine O-methyltransferase activity	F	Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to the oxygen atom of a trihydroxyferuloyl spermidine molecule.
80078	tricaffeoyl spermidine:S-adenosyl-L-methionine O-methyltransferase activity	F	Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to the oxygen atom of a tricaffeoyl spermidine molecule.
80079	cellobiose glucosidase activity	F	Catalysis of the reaction: cellobiose + H2O = 2 D-glucose.
80081	4-methylumbelliferyl-beta-D-glucopyranoside beta-glucosidase activity	F	Catalysis of the hydrolysis of glucosidic link in 4-methylumbelliferyl-beta-D-glucopyranoside.
80082	esculin beta-glucosidase activity	F	Catalysis of the hydrolysis of glucosidic link in esculin.
80083	beta-gentiobiose beta-glucosidase activity	F	Catalysis of the hydrolysis of glucosidic link in beta-gentiobiose.
80084	5S rDNA binding	F	Interacting selectively and non-covalently with the 5S rDNA sequence encoding ribosomal 5S rRNA, which is individually transcribed by RNA polymerase III, rather than by RNA polymerase I, in species where it exists.
80085	signal recognition particle, chloroplast targeting	C	A complex consisting of a protein and RNA component which binds the signal sequence of some proteins and facilitates their export to the chloroplast.
80086	stamen filament development	P	The process whose specific outcome is the progression of the filament over time, from its formation to the mature structure. Filament is the stalk of a stamen.
80088	spermidine hydroxycinnamate conjugate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of spermidine hydroxycinnamate conjugates.
80089	sinapoyl spermidine:sinapoyl CoA N-acyltransferase activity	F	Catalysis of the transfer of a sinapoyl group to a nitrogen atom on a sinapoyl spermidine molecule resulting in the formation of a disinapoyl spermidine derivative.
80090	regulation of primary metabolic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways within a cell or an organism involving those compounds formed as a part of the normal anabolic and catabolic processes. These processes take place in most, if not all, cells of the organism.
80091	regulation of raffinose metabolic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving raffinose.
80092	regulation of pollen tube growth	P	Any process that modulates the frequency, rate or extent of pollen tube growth.
80093	regulation of photorespiration	P	Any process that modulates the rate, frequency or extent of photorespiration. Photorespiration is a light-dependent catabolic process occurring concomitantly with photosynthesis in plants (especially C3 plants) whereby dioxygen (O2) is consumed and carbon dioxide (CO2) is evolved.
80094	response to trehalose-6-phosphate	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a trehalose-6-phosphate stimulus.
80095	phosphatidylethanolamine-sterol O-acyltransferase activity	F	Catalysis of the reaction: a phosphatidylethanolamine + a sterol = a sterol ester + a lysophosphatidylethanolamine.
80096	phosphatidate-sterol O-acyltransferase activity	F	Catalysis of the reaction: a phosphatidate + a sterol = a sterol ester + a lysophosphatidate.
80097	L-tryptophan:pyruvate aminotransferase activity	F	Catalysis of the reaction: L-tryptophan + pyruvate = 3-(indol-3-yl)pyruvate + L-alanine.
80098	L-tyrosine:pyruvate aminotransferase activity	F	Catalysis of the reaction: L-tyrosine + pyruvate = (4-hydroxyphenyl)pyruvate + L-alanine.
80099	L-methionine:2-oxoglutarate aminotransferase activity	F	Catalysis of the reaction: L-methionine + 2-oxoglutarate = 4-methylthio-2-oxobutyrate + L-glutamate.
80100	L-glutamine:2-oxoglutarate aminotransferase activity	F	Catalysis of the reaction: L-glutamine + 2-oxoglutarate = 2-oxoglutaramate + L-glutamate.
80101	phosphatidyl-N-dimethylethanolamine N-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + phosphatidyl-N-dimethylethanolamine = S-adenosyl-L-homocysteine + phosphatidylcholine.
80102	3-methylthiopropyl glucosinolate S-oxygenase activity	F	Catalysis of the reaction: 3-methylthiopropyl-glucosinolate = 3-methylsulfinylpropyl-glucosinolate.
80103	4-methylthiopropyl glucosinolate S-oxygenase activity	F	Catalysis of the reaction: 4-methylthiopropyl-glucosinolate = 4-methylsulfinylpropyl-glucosinolate.
80104	5-methylthiopropyl glucosinolate S-oxygenase activity	F	Catalysis of the reaction: 5-methylthiopropyl-glucosinolate = 5-methylsulfinylpropyl-glucosinolate.
80105	6-methylthiopropyl glucosinolate S-oxygenase activity	F	Catalysis of the reaction: 6-methylthiopropyl-glucosinolate = 6-methylsulfinylpropyl-glucosinolate.
80106	7-methylthiopropyl glucosinolate S-oxygenase activity	F	Catalysis of the reaction: 7-methylthiopropyl-glucosinolate = 7-methylsulfinylpropyl-glucosinolate.
80107	8-methylthiopropyl glucosinolate S-oxygenase activity	F	Catalysis of the reaction: 8-methylthiopropyl-glucosinolate = 8-methylsulfinylpropyl-glucosinolate.
80108	S-alkylthiohydroximate lyase activity	F	Catalysis of the conversion of a S-alkylthiohydroximate to a thiohydroximate.
80109	indole-3-acetonitrile nitrile hydratase activity	F	Catalysis of the reaction: indole-3-acetonitrile + H2O = indole-3-acetamide.
80110	sporopollenin biosynthetic process	P	The chemical reactions and pathways resulting in the formation of sporopollenin, a primary constituent of the pollen exine layer.
80111	DNA demethylation	P	The removal of a methyl group from one or more nucleotides within an DNA molecule.
80112	seed growth	P	The increase in size or mass of a seed. A seed is a propagating organ formed in the reproductive cycle of a spermatophyte, derived from the ovule and enclosing an embryo.
80113	regulation of seed growth	P	Any process that modulates the frequency, rate or extent of growth of the seed of an plant.
80114	positive regulation of glycine hydroxymethyltransferase activity	P	Any process that activates or increases the frequency, rate or extent of glycine hydroxymethyltransferase activity, the catalysis of the reaction 5,10-methylenetetrahydrofolate + glycine + H2O = tetrahydrofolate + L-serine.
80115	myosin XI tail binding	F	Interacting selectively and non-covalently with the tail region of a myosin XI heavy chain.
80116	glucuronoxylan glucuronosyltransferase activity	F	Catalysis of the transfer of glucuronate to the xylan backbone of glucuronoxylan molecule.
80117	secondary growth	P	Lateral growth of a plant axis (shoot axis or root) that is an increase in thickness resulting from formation of secondary vascular tissues by the vascular cambium.
80118	brassinosteroid sulfotransferase activity	F	Catalysis of the reaction: a brassinosteroid + 3'-phosphoadenosine-5'-phosphosulfate = sulfated brassinosteroid + adenosine-3',5'-diphosphate. This reaction is the transfer of a sulfate group to the hydroxyl group of a brassinosteroid acceptor, producing the sulfated brassinosteroid derivative.
80119	ER body organization	P	A process that is carried out at the cellular level which results in the formation of ER (endoplasmic reticulum) body. ER body is a compartment found in plant cells that is derived from the ER. The structures have a characteristic shape and size (10 mm long and 0.5 mm wide) and are surrounded with ribosomes. They have been found in Arabidopsis thaliana and related Brassicaceae species.
80120	CAAX-box protein maturation	P	A series of specific posttranslational modifications to the CAAX box region of CAAX box proteins. CAAX box proteins are eukaryotic proteins that contain a CAAX motif where the C is a cysteine, the two A residues are aliphatic amino acids and the X can be one of several amino acids. The CAAX-box proteins undergo three sequential, enzymatic, post-translational modifications essential to their targeting: First, the proteins are prenylated by one of two prenyltransferases called farnesyltransferase and geranylgeranyltransferase-I. Prenylation results in the covalent attachment of either farnesyl or geranylgeranyl isoprenoid groups to the cysteine in the CAAX box motif. Prenylation is followed by proteolytic removal of the last three amino acids of the protein (AAX). Finally, the newly exposed carboxylate group of the isoprenylcysteine is methylated by an ER-associated prenyl-dependent carboxylmethyltransferase.
80121	AMP transport	P	The directed movement of AMP, adenosine monophosphate, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
80122	AMP transmembrane transporter activity	F	Enables the transfer of AMP, adenosine monophosphate, from one side of a membrane to the other.
80123	jasmonate-amino synthetase activity	F	Catalysis of the reaction: jasmonate + an amino acid = an amide-linked jasmonyl-amino acid conjugate. The substrates of this reaction include non-standard amino acids, such as ACC (1-aminocyclopropane-1-carboxylate).
80124	pheophytinase activity	F	Catalysis of the reaction: pheophytin + H2O = phytol + pheophorbide.
80126	ovary septum development	P	The process whose specific outcome is the progression of the ovary septum over time, from its formation to the mature structure. The ovary septum is the thin partition that divides the ovary, the basal portion of a carpel or group of fused carpels, that encloses the ovule(s).
80127	fruit septum development	P	The process whose specific outcome is the progression of the fruit septum over time, from its formation to the mature structure. The fruit septum is a thin partition or membrane that divides a cavity or a mass of tissue in the fruit.
80128	anther septum development	P	The process whose specific outcome is the progression of the anther septum over time, from its formation to the mature structure. The anther septum is a thin partition or stretch of cells that are present in the anther dehiscence zone.
80129	proteasome core complex assembly	P	The aggregation, arrangement and bonding together of a mature, active 20S proteasome core particle complex that does not contain any regulatory particles.
80130	L-phenylalanine:2-oxoglutarate aminotransferase activity	F	Catalysis of the reaction: L-phenylalanine + 2-oxoglutarate = phenylpyruvate + L-glutamate.
80131	hydroxyjasmonate sulfotransferase activity	F	Catalysis of the reaction: a hydroxyjasmonate + 3'-phosphoadenosine-5'-phosphosulfate = a hydroxyjasmonate sulfate + adenosine-3',5'-diphosphate.
80132	fatty acid alpha-hydroxylase activity	F	Catalysis of the conversion of a fatty acid to an alpha-hydroxylated fatty acid. A hydroxyl group is added to the second carbon, counted from the carboxyl end, of a fatty acid chain.
80133	midchain alkane hydroxylase activity	F	Catalysis of the conversion of an alkane to a secondary alcohol.
80134	regulation of response to stress	P	Any process that modulates the frequency, rate or extent of a response to stress. Response to stress is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis, usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).
80135	regulation of cellular response to stress	P	Any process that modulates the frequency, rate or extent of a cellular response to stress. Cellular response to stress is a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).
80136	priming of cellular response to stress	P	The process that enables cells to respond in a more rapid and robust manner than nonprimed cells to much lower levels of a stimulus indicating the organism is under stress.
80138	borate uptake transmembrane transporter activity	F	Enables the transfer of borate from the outside of a cell to the inside of the cell across a membrane.
80139	borate efflux transmembrane transporter activity	F	Enables the transfer of borate from the inside of the cell to the outside of the cell across a membrane.
80140	regulation of jasmonic acid metabolic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving jasmonic acid.
80141	regulation of jasmonic acid biosynthetic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of jasmonic acid.
80142	regulation of salicylic acid biosynthetic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of salicylic acid.
80143	regulation of amino acid export	P	Any process that modulates the frequency, rate or extent of amino acid export. Amino acid export is the directed movement of amino acids out of a cell or organelle.
80144	amino acid homeostasis	P	Any process involved in the maintenance of an internal steady state of amino acid within an organism or cell.
80145	cysteine homeostasis	P	Any process involved in the maintenance of an internal steady state of cysteine within an organism or cell.
80146	L-cysteine desulfhydrase activity	F	Catalysis of the reaction: L-cysteine + H2O = ammonia + pyruvate + hydrogen sulfide + H+.
80147	root hair cell development	P	The process whose specific outcome is the progression of a root hair cell over time, from its formation to the mature state.
80148	negative regulation of response to water deprivation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of a response to water deprivation. Response to water deprivation is a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a water deprivation stimulus, prolonged deprivation of water.
80149	sucrose induced translational repression	P	Any process that stops, prevents or reduces the rate of translation as a result of increase in sucrose level.
80150	S-adenosyl-L-methionine:benzoic acid carboxyl methyl transferase activity	F	Catalysis of the reaction: benzoate + S-adenosyl-L-methionine = methylbenzoate + S-adenosyl-L-homocysteine.
80151	positive regulation of salicylic acid mediated signaling pathway	P	Any process that activates or increases the frequency, rate or extent of salicylic acid mediated signal transduction.
80152	regulation of reductive pentose-phosphate cycle	P	Any process that modulates the frequency, rate or extent of reductive pentose-phosphate cycle.
80153	negative regulation of reductive pentose-phosphate cycle	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the reductive pentose-phosphate cycle.
80154	regulation of fertilization	P	Any process that modulates the rate, frequency or extent of fertilization. Fertilization is the union of gametes of opposite sexes during the process of sexual reproduction to form a zygote. It involves the fusion of the gametic nuclei (karyogamy) and cytoplasm (plasmogamy).
80155	regulation of double fertilization forming a zygote and endosperm	P	Any process that modulates the rate, frequency or extent of double fertilization forming a zygote and endosperm. Double fertilization forming a zygote and endosperm is a type of fertilization where one of the two sperm nuclei from the pollen tube fuses with the egg nucleus to form a 2n zygote, and the other fuses with the two polar nuclei to form the 3n primary endosperm nucleus and then develops into the endosperm. The ploidy level of the 2n zygote and 3n primary endosperm nucleus is determined by the ploidy level of the parents involved. An example of this component is found in Arabidopsis thaliana.
80156	mitochondrial mRNA modification	P	The covalent alteration within the mitochondrion of one or more nucleotides within an mRNA to produce an mRNA molecule with a sequence that differs from that coded genetically.
80157	regulation of plant-type cell wall organization or biogenesis	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving plant-type cell wall organization or biogenesis. Plant-type cell wall organization or biogenesis is a process that results in the biosynthesis of constituent macromolecules, assembly, arrangement of constituent parts, or disassembly of a cellulose- and pectin-containing cell wall.
80158	chloroplast ribulose bisphosphate carboxylase complex biogenesis	P	A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a chloroplast ribulose bisphosphate carboxylase (RubisCO) complex. Includes the synthesis of the constituent protein molecules, and those protein modifications that are involved in synthesis or assembly of the complex.
80159	zygote elongation	P	The process in which the zygote irreversibly increases in size in one dimension after fertilization. An example of such a process is found in Arabidopsis thaliana.
80160	selenate transport	P	The directed movement of selenate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
80161	auxin transmembrane transporter activity	F	Enables the transfer of auxins from one side of the membrane to the other. Auxins are plant hormones that regulate aspects of plant growth.
80162	intracellular auxin transport	P	The directed movement of auxins within a cell. Auxins are a group of plant hormones that regulates aspects of plant growth.
80163	regulation of protein serine/threonine phosphatase activity	P	Any process that modulates the frequency, rate or extent of protein serine/threonine phosphatase activity: catalysis of the reaction: protein serine/threonine phosphate + H2O = protein serine/threonine + phosphate.
80164	regulation of nitric oxide metabolic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nitric oxide, nitrogen monoxide (NO), a colorless gas only slightly soluble in water.
80165	callose deposition in phloem sieve plate	P	Any process in which callose is transported to, and/or maintained in, phloem sieve plate. Callose is a linear 1,3-beta-d-glucan formed from UDP-glucose and is found in certain plant cell walls.
80166	stomium development	P	The process whose specific outcome is the progression of the stomium over time, from its formation to the mature structure. A stomium is a fissure or pore in the anther lobe through which the pollen is released.
80167	response to karrikin	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a karrikin stimulus. Karrikins are signaling molecules in smoke from burning vegetation that trigger seed germination for many angiosperms (flowering plants).
80168	abscisic acid transport	P	The directed movement of abscisic acid into, out of, within or between cells by means of some external agent such as a transporter or pore.
80169	cellular response to boron-containing substance deprivation	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of boron obtained from boron-containing substances.
80170	hydrogen peroxide transmembrane transport	P	The process in which hydrogen peroxide is transported from one side of a membrane to the other. This process includes the actual movement of the solute, and any regulation and preparatory steps, such as reduction of the solute.
80171	lytic vacuole organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lytic vacuole.
80172	petal epidermis patterning	P	The regionalization process that regulates the coordinated growth and establishes the non-random spatial arrangement of the cells in the petal epidermis.
80173	male-female gamete recognition during double fertilization	P	The initial contact step made between the male gamete and the female gamete during double fertilization. An example can be found in Arabidopsis thaliana.
80175	phragmoplast microtubule organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of structures formed of microtubules and associated proteins in phragmoplast, a plant cell specific structure that forms during late cytokinesis. Phragmoplast serves as a scaffold for cell plate assembly and subsequent formation of a new cell wall separating the two daughter cells.
80176	xyloglucan 1,6-alpha-xylosidase activity	F	Catalysis of the hydrolysis of xyloglucan side chains so as to remove unsubstituted D-xylose residues attached to the glucose located at the non-reducing terminus.
80177	plastoglobule organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the plastoglobule. Plastoglobule is a lipoprotein particle present in chloroplasts. They are rich in non-polar lipids (triglycerides, esters) as well as in prenylquinones, plastoquinone and tocopherols. Plastoglobules are often associated with thylakoid membranes, suggesting an exchange of lipids with thylakoids.
80178	5-carbamoylmethyl uridine residue modification	P	The chemical reactions and pathways involving the addition of a 5-carbamoylmethyl group to a uridine residue in RNA.
80179	1-methylguanosine metabolic process	P	The chemical reactions and pathways involving 1-methylguanosine.
80180	2-methylguanosine metabolic process	P	The chemical reactions and pathways involving 2-methylguanosine.
80181	lateral root branching	P	Any process involved in the formation of branches in lateral roots.
80182	histone H3-K4 trimethylation	P	The modification of histone H3 by addition of three methyl groups to lysine at position 4 of the histone.
80183	response to photooxidative stress	P	Any process that results in a change in state or activity of a cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as the result of a photooxidative stress, the light-dependent generation of active oxygen species. The process begins with detection of the stimulus and ends with a change in state or activity or the cell or organism.
80184	response to phenylpropanoid	P	Any process that results in a change in state or activity of a cell or organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as the result of a phenylpropanoid stimulus. The process begins with detection of the stimulus and ends with a change in state or activity or the cell or organism. A phenylpropanoid is any of secondary metabolites with structures based on a phenylpropane skeleton. The class includes phenylpropanoid esters, flavonoids, anthocyanins, coumarins and many small phenolic molecules. Phenylpropanoids are also precursors of lignin.
80185	effector dependent induction by symbiont of host immune response	P	Any process that involves recognition of an effector, and by which an organism activates, maintains or increases the frequency, rate or extent of the immune response of the host organism; the immune response is any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat. The host is defined as the larger of the organisms involved in a symbiotic interaction. Effectors are proteins secreted into the host cell by pathogenic microbes, presumably to alter host immune response signaling. The best characterized effectors are bacterial effectors delivered into the host cell by type III secretion system (TTSS). Effector-triggered immunity (ETI) involves the direct or indirect recognition of an effector protein by the host (for example through plant resistance or R proteins) and subsequent activation of host immune response.
80186	developmental vegetative growth	P	The increase in size or mass of non-reproductive plant parts.
80187	floral organ senescence	P	An organ senescence that has as a participant a floral organ.
80188	RNA-directed DNA methylation	P	An epigenetic RNA-based gene silencing process first elucidated in plants whereby 24-nt small interfering RNAs (siRNAs) guide DNA methyltransferases to the siRNA-generating genomic loci and other loci that are homologous to the siRNAs for de novo DNA methylation. In general this process consists of three phases: biogenesis of siRNAs, scaffold RNA production, and the formation of the guiding complex that recruits de novo DNA methyltransferases to the target loci.
80189	primary growth	P	Growth of a plant structure from the time of its initiation by an apical meristem until its expansion is completed.
80190	lateral growth	P	Growth of a plant axis (shoot axis or root) that originates from a lateral meristem.
80191	secondary thickening	P	Lateral growth of a plant axis (shoot axis or root) that is an increase in thickness resulting from formation of tissue from a secondary thickening meristem.
80192	primary thickening	P	Lateral growth of a plant axis (shoot axis or root) that is an increase in thickness resulting from the activity of a primary thickening meristem.
80193	diffuse secondary thickening	P	Lateral growth of the older parts of a stem that occurs when the central parenchyma cells and the not yet fully differentiated fiber cells of the bundle sheaths continue to undergo cell division and expansion for a long period of time, leading to an increase in girth of the stem.
85000	modification by symbiont of host morphology or physiology via protein secreted by type V secretion system	P	The process in which an organism effects a change in the structure or function of its host organism, mediated by a substance secreted by a type V secretion system in the organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
85001	formation by symbiont of stylet for nutrient acquisition from host	P	The assembly by a symbiont of a stylet, a hollow protrusible spear-like structure projected into the host cell for the purpose of obtaining nutrients from its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
85002	interaction with host mediated by secreted substance released by symbiont from symbiotic structure	P	An interaction with the host organism mediated by a symbiont secreted substance released by specialized structures generated in either organisms as a result of the symbiotic interaction. The term host is used for the larger (macro) of the two members of a symbiosis.
85003	interaction with host via secreted substance released from stylet	P	An interaction with the host organism mediated by a substance released by the other (symbiont) organism via the stylet, a hollow protrusible spear-like structure in the symbiont. The host is defined as the larger of the organisms involved in a symbiotic interaction.
85004	interaction with host via secreted substance released from haustorium	P	An interaction with the host organism mediated by a substance released by the other (symbiont) organism via the haustorium, a projection from a cell or tissue that penetrates the host's cell wall. The host is defined as the larger of the organisms involved in a symbiotic interaction.
85005	interaction with host via secreted substance released from invasive hyphae	P	An interaction with the host organism mediated by a substance released by the other (symbiont) organism via invasive hyphae. The host is defined as the larger of the organisms involved in a symbiotic interaction.
85006	interaction with host mediated by symbiont secreted substance released from symbiont-containing vacuole	P	An interaction with the host organism mediated by a substance released by the other (symbiont) organism via a symbiont-containing vacuole, a specialized sac within the host in which the symbiont resides. The host is defined as the larger of the organisms involved in a symbiotic interaction.
85007	interaction with host via secreted substance released from rhoptry	P	An interaction with the host organism mediated by a substance released by the other (symbiont) organism via the rhoptry, a large, club-shaped secretory organelle that forms part of the apical complex of an apicomplexan parasite. The host is defined as the larger of the organisms involved in a symbiotic interaction.
85008	interaction with host via secreted substance released from microneme	P	An interaction with the host organism mediated by a substance released by the other (symbiont) organism via the microneme, a small, elongated secretory organelle that forms part of the apical complex of an apicomplexan parasite. The host is defined as the larger of the organisms involved in a symbiotic interaction.
85009	interaction with host mediated by symbiont secreted substance released from Maurer's cleft	P	An interaction with the host organism mediated by a substance released by the other (symbiont) organism via Maurer's cleft. The host is defined as the larger of the organisms involved in a symbiotic interaction.
85010	interaction with host mediated by secreted substance entering host via endocytosis	P	An interaction with the host organism mediated by a secreted substance from the symbiont entering host cells via endocytosis of the substance. The host is defined as the larger of the organisms involved in a symbiotic interaction.
85011	interaction with host via protein secreted by Sec complex	P	An interaction with the host organism mediated by a substance secreted by the symbiont organism by a Sec complex. The host is defined as the larger of the organisms involved in a symbiotic interaction.
85012	interaction with host via protein secreted by Tat complex	P	An interaction with the host organism mediated by a substance secreted by the symbiont organism by a Tat complex. The host is defined as the larger of the organisms involved in a symbiotic interaction.
85013	interaction with host via protein secreted by type VII secretion system	P	An interaction with the host organism mediated by a substance secreted by the symbiont organism by a type VII secretion system. The host is defined as the larger of the organisms involved in a symbiotic interaction.
85014	dormancy entry of symbiont in host	P	Entry into a dormant state of the symbiont within the host organism.
85015	dormancy maintenance of symbiont in host	P	Any process in which a dormant state is maintained by the symbiont within the host organism.
85016	dormancy exit of symbiont in host	P	Exit from dormant state, also known as resuscitation, of the symbiont within the host organism.
85017	symbiont entry into host cell forming a symbiont-containing vacuole	P	The invasion by a symbiont of a cell of its host organism, forming a vacuole in which the parasite resides. The vacuole membrane is formed from lipids and proteins derived from both host and symbiont. Begins when the symbiont attaches on to the host cell membrane which invaginates and deepens as the symbiont enters, and ends when the host cell membrane closes behind the newly-formed vacuole.
85018	maintenance of symbiont-containing vacuole by host	P	The process in which a host organism maintains the structure and function of a symbiont-containing vacuole. The symbiont-containing vacuole is a membrane-bounded vacuole within a host cell in which a symbiont organism resides, and can serve to reduce pathogenicity of invading symbionts by restricting them to the vacuolar compartment.
85019	formation by symbiont of a tubovesicular network for nutrient acquisition from host	P	The assembly of a symbiont-induced complex organelle that comprises of multiple protein and lipid domains for the purpose of obtaining nutrients from its host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
85020	protein K6-linked ubiquitination	P	A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 6 of the ubiquitin monomers, is added to a protein. K6-linked ubiquitination is involved in DNA repair.
85021	modification by symbiont of host morphology or physiology via protein secreted by type I secretion system	P	The process in which an organism effects a change in the structure or function of its host organism, mediated by a substance secreted by a type I secretion system in the organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
85022	modification by symbiont of host morphology or physiology via protein secreted by type VI secretion system	P	The process in which an organism effects a change in the structure or function of its host organism, mediated by a substance secreted by a type VI secretion system in the organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
85023	modification by symbiont of host morphology or physiology via protein secreted by type VII secretion system	P	The process in which an organism effects a change in the structure or function of its host organism, mediated by a substance secreted by a type VII secretion system in the organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
85024	modification by symbiont of host morphology or physiology via protein secreted by Sec complex	P	The process in which an organism (symbiont) effects a change in the structure or function of its host organism, mediated by a substance secreted by the Sec complex in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
85025	modification by symbiont of host morphology or physiology via protein secreted by Tat complex	P	The process in which an organism (symbiont) effects a change in the structure or function of its host organism, mediated by a substance secreted by the Tat complex in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
85026	tubovesicular membrane network	C	A complex, symbiont-induced host-derived organelle that is comprised of multiple protein and lipid domains.
85027	entry into host via enzymatic degradation of host anatomical structure	P	Penetration by symbiont of a host anatomical structure which provides a barrier to symbiont entry, mediated by symbiont degradative enzymes.
85028	entry into host via enzymatic degradation of host cuticle	P	Penetration by symbiont of host physical barriers, mediated by symbiont degradative enzymes.
85029	extracellular matrix assembly	P	The aggregation, arrangement and bonding together of the extracellular matrix.
85030	mutualism	P	An interaction between two organisms living together in more or less intimate association in a relationship in which both organisms benefit from each other.
85031	commensalism	P	An interaction between two organisms living together in more or less intimate association in a relationship in which one benefits and the other is unaffected.
85032	modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade	P	Any process in which an organism modulates the frequency, rate or extent of host NF-kappaB-mediated signal transduction pathways during the host defense response. The host is defined as the larger of the organisms involved in a symbiotic interaction.
85033	positive regulation by symbiont of host I-kappaB kinase/NF-kappaB cascade	P	Any process that activates or increases the frequency, rate or extent of host NF-kappaB-mediated signal transduction pathways during the host defense response. The host is defined as the larger of the organisms involved in a symbiotic interaction.
85034	negative regulation by symbiont of host I-kappaB kinase/NF-kappaB cascade	P	Any process that stops, prevents, or reduces the frequency, rate or extent of host NF-kappaB-mediated signal transduction pathways during the host defense response. The host is defined as the larger of the organisms involved in a symbiotic interaction.
85035	haustorium	C	A projection from a cell or tissue that penetrates the host's cell wall and invaginates the host cell membrane.
85036	extrahaustorial matrix	C	The space between the symbiont plasma membrane and the extrahaustorial membrane of the host.
85037	extrahaustorial membrane	C	The membrane surrounding the symbiont haustorium during symbiosis, derived from the host plasma membrane.
85039	extra-invasive hyphal membrane	C	A host-derived membrane surrounding the symbiont invasive hypha during symbiosis.
85040	extra-invasive hyphal space	C	The space between the symbiont plasma membrane and the extra-invasive hyphal membrane.
85041	arbuscule	C	Highly branched symbiont haustoria within host root cortex cells, responsible for nutrient exchange.
85042	periarbuscular membrane	C	A host-derived membrane surrounding the symbiont arbuscule during symbiosis.
85044	disassembly by symbiont of host cuticle	P	The process in which a symbiont organism effects a breakdown of the host organism cuticle. The host is defined as the larger of the organisms involved in a symbiotic interaction.
86001	cardiac muscle cell action potential	P	An action potential that occurs in a cardiac muscle cell.
86002	cardiac muscle cell action potential involved in contraction	P	An action potential that occurs in a cardiac muscle cell and is involved in its contraction.
86003	cardiac muscle cell contraction	P	The actin filament-based process in which cytoplasmic actin filaments slide past one another resulting in contraction of a cardiac muscle cell.
86004	regulation of cardiac muscle cell contraction	P	Any process that modulates the frequency, rate or extent of cardiac muscle cell contraction.
86005	ventricular cardiac muscle cell action potential	P	An action potential that occurs in a ventricular cardiac muscle cell.
86006	voltage-gated sodium channel activity involved in cardiac muscle cell action potential	F	Enables the transmembrane transfer of a sodium ion by a voltage-gated channel through the plasma membrane of a cardiac muscle cell contributing to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.
86007	voltage-gated calcium channel activity involved in cardiac muscle cell action potential	F	Enables the transmembrane transfer of a calcium ion by a voltage-gated channel across the plasma membrane of a cardiac muscle cell that contributes to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.
86008	voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization	F	Enables the transmembrane transfer of a potassium ion by a voltage-gated channel through the plasma membrane of a cardiac muscle cell contributing to the repolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.
86009	membrane repolarization	P	The process in which ions are transported across a membrane such that the membrane potential changes in the repolarizing direction, toward the steady state potential. For example, the repolarization during an action potential is from a positive membrane potential towards a negative resting potential.
86010	membrane depolarization during action potential	P	The process in which membrane potential changes in the depolarizing direction from the negative resting potential towards the positive membrane potential that will be the peak of the action potential.
86011	membrane repolarization during action potential	P	The process in which ions are transported across a membrane such that the membrane potential changes in the direction from the positive membrane potential at the peak of the action potential towards the negative resting potential.
86012	membrane depolarization during cardiac muscle cell action potential	P	The process in which cardiac muscle cell membrane potential changes in the depolarizing direction from the negative resting potential towards the positive membrane potential that will be the peak of the action potential.
86013	membrane repolarization during cardiac muscle cell action potential	P	The process in which ions are transported across a membrane such that the cardiac muscle cell plasma membrane potential changes in the direction from the positive membrane potential at the peak of the action potential towards the negative resting potential.
86014	atrial cardiac muscle cell action potential	P	An action potential that occurs in an atrial cardiac muscle cell.
86015	SA node cell action potential	P	An action potential that occurs in a sinoatrial node cardiac muscle cell.
86016	AV node cell action potential	P	An action potential that occurs in an atrioventricular node cardiac muscle cell.
86017	Purkinje myocyte action potential	P	An action potential that occurs in a Purkinje myocyte.
86018	SA node cell to atrial cardiac muscle cell signalling	P	Any process that mediates the transfer of information from an SA node cardiomyocyte to an atrial cardiomyocyte.
86019	cell-cell signaling involved in cardiac conduction	P	Any process that mediates the transfer of information from one cell to another and contributes to the heart process that regulates cardiac muscle contraction; beginning with the generation of an action potential in the sinoatrial node and ending with regulation of contraction of the myocardium.
86020	gap junction channel activity involved in SA node cell-atrial cardiac muscle cell electrical coupling	F	A wide pore channel activity that enables a direct cytoplasmic connection from an SA node cell to an atrial cardiomyocyte. The gap junction passes electrical signals between the cells contributing to cardiac conduction.
86021	SA node cell to atrial cardiac muscle cell communication by electrical coupling	P	The process that mediates signaling interactions between an SA node cardiomyocyte and an atrial cardiomyocyte by transfer of current between their adjacent cytoplasms via intercellular protein channels.
86022	SA node cell-atrial cardiac muscle cell adhesion involved in cell communication	P	The attachment of SA node cardiomyocyte to an atrial cardiomyocyte via adhesion molecules that results in the cells being juxtaposed so that they can communicate.
86023	adrenergic receptor signaling pathway involved in heart process	P	A series of molecular signals beginning with a G-protein coupled adrenergic cell surface receptor combining with epinephrine or norepinephrine, which contributes to a circulatory system process carried out by the heart.
86024	adrenergic receptor signaling pathway involved in positive regulation of heart rate	P	An adrenergic receptor signaling pathway that contributes to an increase in frequency or rate of heart contraction. Binding of adrenalin or noradrenalin to a beta-adrenergic receptor on the surface of the signal-receiving cell results in the activation of an intracellular Gs protein. Gs activates adenylate cyclase to increase intracellular cyclic-AMP (cAMP) levels. cAMP binds directly to F-channels to allow an inward flow of sodium (known as funny current, or If current). The funny current is responsible for membrane depolarization and an increase in heart rate.
86026	atrial cardiac muscle cell to AV node cell signaling	P	Any process that mediates the transfer of information from an atrial cardiomyocyte to an AV node cell.
86027	AV node cell to bundle of His cell signaling	P	Any process that mediates the transfer of information from an AV node cardiac muscle cell to a bundle of His cardiomyocyte.
86028	bundle of His cell to Purkinje myocyte signaling	P	Any process that mediates the transfer of information from a bundle of His cardiomyocyte to a Purkinje myocyte.
86029	Purkinje myocyte to ventricular cardiac muscle cell signaling	P	Any process that mediates the transfer of information from a Purkinje myocyte to a ventricular cardiac muscle cell.
86030	adrenergic receptor signaling pathway involved in cardiac muscle relaxation	P	An adrenergic receptor signaling pathway that contributes to a reduction in cardiac muscle contraction. Beta-adrenergic receptor-induced cardiac relaxation is achieved by a GPCR-activated adenylate cyclase generating cAMP; cAMP then activates the cAMP-dependent protein kinase A (PKA), which phosphorylates the sarcoplasmic reticulum (SR) membrane protein PLB. In its non-phosphorylated state, PLB acts as an inhibitor of the ATPase Ca(2+) pump of the cardiac SR (SERCA2a); inhibition of the pump is relieved upon phosphorylation. The pump removes Ca(2+) from the cytoplasm, thereby preventing cytosolic Ca(2+)-dependent activation of contractile proteins, leading to enhanced muscle relaxation.
86033	G-protein coupled acetylcholine receptor signaling pathway involved in negative regulation of heart rate	P	A G-protein coupled acetylcholine receptor signaling pathway that contributes to a decrease in frequency or rate of heart contraction. Binding of acetylcholine to a G-protein coupled (muscarinic) receptor on the surface of the signal-receiving cell results in the alpha subunit of a coupled G-protein binding to GTP. This results in the separation of the beta-gamma complex from the alpha subunit. Both the alpha subunit, and the beta-gamma complex can continue to signal to bring about membrane hyperpolarization and a reduction in heart rate.
86036	regulation of cardiac muscle cell membrane potential	P	Any process that modulates the establishment or extent of a membrane potential in a cardiac muscle cell (a cardiomyocyte). A membrane potential is the electric potential existing across any membrane arising from charges in the membrane itself and from the charges present in the media on either side of the membrane.
86037	sodium:potassium-exchanging ATPase activity involved in regulation of cardiac muscle cell membrane potential	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + Na+(in) + K+(out) = ADP + phosphate + Na+(out) + K+(in), that contributes to regulating the membrane potential of a cardiac muscle cell.
86038	calcium:sodium antiporter activity involved in regulation of cardiac muscle cell membrane potential	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: Ca2+(in) + Na+(out) = Ca2+(out) + Na+(in), which contributes to regulating the membrane potential of a cardiac muscle cell.
86039	calcium-transporting ATPase activity involved in regulation of cardiac muscle cell membrane potential	F	Catalysis of the transfer of a solute or solutes from one side of a cardiac muscle cell plasma membrane to the other according to the reaction: ATP + H2O + Ca2+(cis) = ADP + phosphate + Ca2+(trans). The transfer contributes to the regulation of the plasma membrane potential.
86040	sodium:proton antiporter activity involved in regulation of cardiac muscle cell membrane potential	F	Catalysis of the transfer of a solute or solutes from one side of a cardiac muscle cell membrane to the other according to the reaction: Na+(out) + H+(in) = Na+(in) + H+(out). This transfer contributes to the regulation of the cardiac muscle cell plasma membrane potential.
86041	voltage-gated potassium channel activity involved in SA node cell action potential depolarization	F	Enables the transmembrane transfer of a potassium ion by a voltage-gated channel through the plasma membrane of an SA node cardiac muscle cell contributing to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.
86042	cardiac muscle cell-cardiac muscle cell adhesion	P	The attachment of one cardiomyocyte to another cardiomyocyte via adhesion molecules.
86043	bundle of His cell action potential	P	An action potential that occurs in a bundle of His cell.
86044	atrial cardiac muscle cell to AV node cell communication by electrical coupling	P	The process that mediates signaling interactions between an atrial cardiomyocyte and an AV node cell by transfer of current between their adjacent cytoplasms via intercellular protein channels.
86045	membrane depolarization during AV node cell action potential	P	The process in which AV node cardiac muscle cell membrane potential changes in the depolarizing direction from the negative resting potential towards the positive membrane potential that will be the peak of the action potential.
86046	membrane depolarization during SA node cell action potential	P	The process in which SA node cardiac muscle cell membrane potential changes in the depolarizing direction from the negative resting potential towards the positive membrane potential that will be the peak of the action potential.
86047	membrane depolarization during Purkinje myocyte cell action potential	P	The process in which Purkinje myocyte membrane potential changes in the depolarizing direction from the negative resting potential towards the positive membrane potential that will be the peak of the action potential.
86048	membrane depolarization during bundle of His cell action potential	P	The process in which bundle of His cardiac muscle cell membrane potential changes in the depolarizing direction from the negative resting potential towards the positive membrane potential that will be the peak of the action potential.
86049	membrane repolarization during AV node cell action potential	P	The process in which ions are transported across a membrane such that the AV node cardiac muscle cell membrane potential changes in the direction from the positive membrane potential at the peak of the action potential towards the negative resting potential.
86050	membrane repolarization during bundle of His cell action potential	P	The process in which ions are transported across a membrane such that the bundle of His cardiac muscle cell membrane potential changes in the direction from the positive membrane potential at the peak of the action potential towards the negative resting potential.
86051	membrane repolarization during Purkinje myocyte action potential	P	The process in which ions are transported across a membrane such that the Purkinje myocyte membrane potential changes in the direction from the positive membrane potential at the peak of the action potential towards the negative resting potential.
86052	membrane repolarization during SA node cell action potential	P	The process in which an SA node cardiac muscle cell membrane potential changes in the direction from the positive membrane potential at the peak of the action potential towards the negative resting potential.
86053	AV node cell to bundle of His cell communication by electrical coupling	P	The process that mediates signaling interactions between an AV node cardiomyocyte and a bundle of His cardiac muscle cell by transfer of current between their adjacent cytoplasms via intercellular protein channels.
86054	bundle of His cell to Purkinje myocyte communication by electrical coupling	P	The process that mediates signaling interactions between a bundle of His cardiac muscle cell and a Purkinje myocyte by transfer of current between their adjacent cytoplasms via intercellular protein channels.
86055	Purkinje myocyte to ventricular cardiac muscle cell communication by electrical coupling	P	The process that mediates signaling interactions between a Purkinje myocyte and a ventricular cardiac muscle cell by transfer of current between their adjacent cytoplasms via intercellular protein channels.
86056	voltage-gated calcium channel activity involved in AV node cell action potential	F	Enables the transmembrane transfer of a calcium ion by a voltage-gated channel across the plasma membrane of an AV node cardiac muscle cell that contributes to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.
86057	voltage-gated calcium channel activity involved in bundle of His cell action potential	F	Enables the transmembrane transfer of a calcium ion by a voltage-gated channel across the plasma membrane of a bundle of His cardiac muscle cell that contributes to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.
86058	voltage-gated calcium channel activity involved in Purkinje myocyte cell action potential	F	Enables the transmembrane transfer of a calcium ion by a voltage-gated channel across the plasma membrane of an Purkinje myocyte cell that contributes to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.
86059	voltage-gated calcium channel activity involved SA node cell action potential	F	Enables the transmembrane transfer of a calcium ion by a voltage-gated channel across the plasma membrane of an SA node cardiac muscle cell that contributes to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.
86060	voltage-gated sodium channel activity involved in AV node cell action potential	F	Enables the transmembrane transfer of a sodium ion by a voltage-gated channel through the plasma membrane of an AV node cardiac muscle cell contributing to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.
86061	voltage-gated sodium channel activity involved in bundle of His cell action potential	F	Enables the transmembrane transfer of a sodium ion by a voltage-gated channel through the plasma membrane of a bundle of His cardiac muscle cell contributing to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.
86062	voltage-gated sodium channel activity involved in Purkinje myocyte action potential	F	Enables the transmembrane transfer of a sodium ion by a voltage-gated channel through the plasma membrane of a Purkinje myocyte contributing to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.
86063	voltage-gated sodium channel activity involved in SA node cell action potential	F	Enables the transmembrane transfer of a sodium ion by a voltage-gated channel through the plasma membrane of an SA node cardiac muscle cell contributing to the depolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.
86064	cell communication by electrical coupling involved in cardiac conduction	P	The process that mediates signaling interactions between one cell and another cell by transfer of current between their adjacent cytoplasms via intercellular protein channels and contributes to the process of cardiac conduction.
86065	cell communication involved in cardiac conduction	P	Any process that mediates interactions between a cell and its surroundings that contributes to the process of cardiac conduction. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.
86066	atrial cardiac muscle cell to AV node cell communication	P	The process that mediates interactions between an atrial cardiomyocyte and its surroundings that contributes to the process of the atrial cardiomyocyte communicating with an AV node cell in cardiac conduction. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.
86067	AV node cell to bundle of His cell communication	P	The process that mediates interactions between an AV node cell and its surroundings that contributes to the process of the AV node cell communicating with a bundle of His cell in cardiac conduction. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.
86068	Purkinje myocyte to ventricular cardiac muscle cell communication	P	The process that mediates interactions between a Purkinje myocyte and its surroundings that contributes to the process of the Purkinje myocyte communicating with a ventricular cardiac muscle cell in cardiac conduction. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.
86069	bundle of His cell to Purkinje myocyte communication	P	The process that mediates interactions between a bundle of His cell and its surroundings that contributes to the process of the bundle of His cell communicating with a Purkinje myocyte in cardiac conduction. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.
86070	SA node cell to atrial cardiac muscle cell communication	P	The process that mediates interactions between an SA node cardiomyocyte and its surroundings that contributes to the process of the SA node cardiomyocyte communicating with an atrial cardiomyocyte in cardiac conduction. Encompasses interactions such as signaling or attachment between one cell and another cell, between a cell and an extracellular matrix, or between a cell and any other aspect of its environment.
86071	atrial cardiac muscle cell-AV node cell adhesion involved in cell communication	P	The attachment of an atrial cardiomyocyte to an AV node cell via adhesion molecules that results in the cells being juxtaposed so that they can communicate.
86072	AV node cell-bundle of His cell adhesion involved in cell communication	P	The attachment of an AV node cell to an bundle of His cell via adhesion molecules that results in the cells being juxtaposed so that they can communicate.
86073	bundle of His cell-Purkinje myocyte adhesion involved in cell communication	P	The attachment of a bundle of His cell to a Purkinje myocyte via adhesion molecules that results in the cells being juxtaposed so that they can communicate.
86074	Purkinje myocyte-ventricular cardiac muscle cell adhesion involved in cell communication	P	The attachment of an Purkinje myocyte to a ventricular cardiac muscle cell via adhesion molecules that results in the cells being juxtaposed so that they can communicate.
86075	gap junction channel activity involved in cardiac conduction electrical coupling	F	A wide pore channel activity that enables a direct cytoplasmic connection from one cardiomyocyte to an adjacent cardiomyocyte. The gap junction passes electrical signals between the cells contributing to cardiac conduction.
86076	gap junction channel activity involved in atrial cardiac muscle cell-AV node cell electrical coupling	F	A wide pore channel activity that enables a direct cytoplasmic connection from an atrial cardiomyocyte to an AV node cell. The gap junction passes electrical signals between the cells contributing to cardiac conduction.
86077	gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling	F	A wide pore channel activity that enables a direct cytoplasmic connection from an AV node cell to a bundle of His cell. The gap junction passes electrical signals between the cells contributing to cardiac conduction.
86078	gap junction channel activity involved in bundle of His cell-Purkinje myocyte electrical coupling	F	A wide pore channel activity that enables a direct cytoplasmic connection from a bundle of His cell to a Purkinje myocyte. The gap junction passes electrical signals between the cells contributing to cardiac conduction.
86079	gap junction channel activity involved in Purkinje myocyte-ventricular cardiac muscle cell electrical coupling	F	A wide pore channel activity that enables a direct cytoplasmic connection from a Purkinje myocyte to a ventricular cardiac muscle cell. The gap junction passes electrical signals between the cells contributing to cardiac conduction.
86080	protein binding involved in heterotypic cell-cell adhesion	F	Interacting selectively and non-covalently with any protein or protein complex contributing to the adhesion of two different types of cells.
86081	cell adhesive protein binding involved in atrial cardiac muscle cell-AV node cell communication	F	Interacting selectively and non-covalently with any protein or protein complex that results in the connection of an atrial cardiomyocyte with an AV node cell and contributes to the communication between the two cells.
86082	cell adhesive protein binding involved in AV node cell-bundle of His cell communication	F	Interacting selectively and non-covalently with any protein or protein complex that results in the connection of an AV node cell with a bundle of His cell and contributes to the communication between the two cells.
86083	cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication	F	Interacting selectively and non-covalently with any protein or protein complex that results in the connection of a bundle of His cell with a Purkinje myocyte and contributes to the communication between the two cells.
86084	cell adhesive protein binding involved in Purkinje myocyte-ventricular cardiac muscle cell communication	F	Interacting selectively and non-covalently with any protein or protein complex that results in the connection of a Purkinje myocyte with an ventricular cardiac muscle cell and contributes to the communication between the two cells.
86085	cell adhesive protein binding involved in SA cardiac muscle cell-atrial cardiac muscle cell communication	F	Interacting selectively and non-covalently with any protein or protein complex that results in the connection of an SA cardiomyocyte with an atrial cardiomyocyte and contributes to the communication between the two cells.
86086	voltage-gated potassium channel activity involved in AV node cell action potential repolarization	F	Catalysis of the transmembrane transfer of a potassium ion by a voltage-gated channel through the plasma membrane of an AV node cardiac muscle cell contributing to the repolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.
86087	voltage-gated potassium channel activity involved in bundle of His cell action potential repolarization	F	Enables the transmembrane transfer of a potassium ion by a voltage-gated channel through the plasma membrane of a bundle of His cell contributing to the repolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.
86088	voltage-gated potassium channel activity involved in Purkinje myocyte action potential repolarization	F	Enables the transmembrane transfer of a potassium ion by a voltage-gated channel through the plasma membrane of a Purkinje myocyte contributing to the repolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.
86089	voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization	F	Enables the transmembrane transfer of a potassium ion by a voltage-gated channel through the plasma membrane of an atrial cardiomyocyte contributing to the repolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.
86090	voltage-gated potassium channel activity involved in SA node cell action potential repolarization	F	Enables the transmembrane transfer of a potassium ion by a voltage-gated channel through the plasma membrane of an SA node cell contributing to the repolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.
86091	regulation of heart rate by cardiac conduction	P	A cardiac conduction process that modulates the frequency or rate of heart contraction.
86092	regulation of the force of heart contraction by cardiac conduction	P	A cardiac conduction process that modulates the extent of heart contraction, changing the force with which blood is propelled.
86093	G-protein coupled acetylcholine receptor signaling pathway involved in heart process	P	A G-protein coupled acetylcholine receptor signaling pathway, which contributes to a circulatory system process carried out by the heart.
86094	positive regulation of ryanodine-sensitive calcium-release channel activity by adrenergic receptor signaling pathway involved in positive regulation of cardiac muscle contraction	P	An adrenergic receptor signaling pathway that contributes to an increase in frequency or rate of cardiac muscle contraction through phosphorylation and enhancement of the ryanodine receptor, a calcium-activated calcium-release channel found in the membrane of the sarcoplasmic reticulum. An adrenergic receptor-activated adenylate cyclase generates cAMP. cAMP then activates the cAMP-dependent protein kinase A (PKA), which phosphorylates the ryanodine receptor (RyR). PKA-phosphorylation of RyR enhances channel activity by sensitizing the channel to cytosolic calcium. Cytosolic calcium stimulates contractile proteins to promote muscle contraction.
86095	positive regulation of IKACh channel activity by G-protein coupled acetylcholine receptor signaling pathway involved in negative regulation of heart rate	P	A G-protein coupled acetylcholine receptor signaling pathway that contributes to a decrease in frequency or rate of heart contraction through activation of the IKACh potassium channel. Binding of acetylcholine to a G-protein coupled acetylcholine receptor (muscarinic receptor) on the surface of the signal-receiving cell results in liberation of the G-beta/gamma complex from the alpha subunit. The G-beta/gamma complex binds directly to the inward-rectifying potassium channel IKACh. Once the ion channel is activated, potassium ions (K+) flow out of the cell and cause it to hyperpolarize. In its hyperpolarized state, action potentials cannot be fired as quickly as possible, which slows the heart rate.
86096	adenylate cyclase-inhibiting adrenergic receptor signaling pathway involved in heart process	P	An adrenergic receptor signaling pathway which contributes to a circulatory system process carried out by the heart, where the activated adrenergic receptor transmits the signal by Gi-mediated inhibition of adenylate cyclase activity.
86097	phospholipase C-activating angiotensin-activated signaling pathway	P	An angiotensin-mediated signaling pathway where the activated receptor transmits the signal via Gq-mediated activation of phospholipase C (PLC). PLC hydrolyses phosphatidylinositol 4,5-bisphosphate (PIP2) into the second messengers inositol-1,4,5,-triphosphate (IP3) and diacylglycerol (DAG). DAG activates protein kinase C (PKC), whilst IP3 binds intracellular receptors to induce the release of Ca2+ from intracellular stores.
86098	angiotensin-activated signaling pathway involved in heart process	P	An angiotensin receptor signaling pathway which contributes to a circulatory system process carried out by the heart.
86099	phospholipase C-activating angiotensin-activated signaling pathway involved in heart process	P	An angiotensin-mediated signaling pathway that contributes to a circulatory system process carried out by the heart, where the activated receptor transmits the signal via Gq-mediated activation of phospholipase C (PLC). PLC hydrolyses phosphatidylinositol 4,5-bisphosphate (PIP2) into the second messengers inositol-1,4,5,-triphosphate (IP3) and diacylglycerol (DAG). DAG activates protein kinase C (PKC), whilst IP3 binds intracellular receptors to induce the release of Ca2+ from intracellular stores.
86100	endothelin receptor signaling pathway	P	A series of molecular signals initiated by an endothelin receptor binding to one of its physiological ligands, and proceeding with the activated receptor promoting the exchange of GDP for GTP on the alpha-subunit of an associated heterotrimeric G-protein complex. Ends with regulation of a downstream cellular process, e.g. transcription.
86101	endothelin receptor signaling pathway involved in heart process	P	An endothelin receptor signaling pathway which contributes to a circulatory system process carried out by the heart.
86102	adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway involved in negative regulation of heart rate	P	A G-protein coupled acetylcholine receptor signaling pathway that contributes to an decrease in frequency or rate of heart contraction through inhibition of adenylate cyclase (AC) activity. Binding of acetylcholine to a G-protein coupled (muscarinic) receptor on the surface of the signal-receiving cell results in the activation of an intracellular Gi/o protein. Gi/o inhibits adenylate cyclase to decrease cyclic-AMP (cAMP) levels. Since cAMP binds directly to F-channels to allow an inward flow of sodium (funny current, If current), a reduction in cAMP reduces the funny current to bring about membrane hyperpolarization and a decrease in heart rate.
86103	G-protein coupled receptor signaling pathway involved in heart process	P	An G-protein coupled receptor signaling pathway which contributes to a circulatory system process carried out by the heart.
89700	protein kinase D signaling	P	A series of reactions, mediated by the intracellular serine/threonine kinase protein kinase D, which occurs as a result of a single trigger reaction or compound.
89701	U2AF	C	A heterodimeric protein complex consisting of conserved large and small U2AF subunits that contributes to spliceosomal RNA splicing by binding to consensus sequences at the 3' splice site. U2AF is required to stabilize the association of the U2 snRNP with the branch point.
89702	undecaprenyl-phosphate glucose phosphotransferase activity	F	Catalysis of the reaction: UDP-glucose + ditrans,octacis-undecaprenyl phosphate = UMP + alpha-D-glucopyranosyl-diphospho-ditrans,octacis-undecaprenol.
89703	L-aspartate transmembrane export from vacuole	P	The directed movement of L-aspartate out of the vacuole, across the vacuolar membrane.
89704	L-glutamate transmembrane export from vacuole	P	The directed movement of L-glutamate out of the vacuole, across the vacuolar membrane.
89705	protein localization to outer membrane	P	A process in which a protein is transported to, or maintained in, a specific location the cell outer membrane.
89706	L-ornithine transmembrane export from vacuole	P	The directed movement of L-ornithine out of the vacuole, across the vacuolar membrane.
89707	L-lysine transmembrane export from vacuole	P	The directed movement of L-lysine out of the vacuole, across the vacuolar membrane.
89708	L-histidine transmembrane export from vacuole	P	The directed movement of L-histidine out of the vacuole, across the vacuolar membrane.
89709	L-histidine transmembrane transport	P	The directed movement of L-histidine across a membrane.
89710	endocytic targeting sequence binding	F	Interacting selectively and non-covalently with a endocytic signal sequence, a specific peptide sequence, of 4-6 amino acids with an essential tyrosine (Y), found on cytoplasmic tails of some cell surface membrane proteins, which directs internalization by clathrin-coated pits.
89711	L-glutamate transmembrane transport	P	The directed movement of L-glutamate across a membrane.
89712	L-aspartate transmembrane transport	P	The directed movement of L-aspartate across a membrane.
89713	Cbf1-Met4-Met28 complex	C	A heteromeric complex consisting of Cbf1 and basic leucine zipper (bZIP) containing transcriptional activators, Met4 and Met28, that forms over the sequence TCACGTG in the upstream activating sequence (UAS) of genes involved in sulfur amino acid metabolism, resulting in their transcriptional activation.
89714	UDP-N-acetyl-D-mannosamine dehydrogenase activity	F	Catalysis of the reaction: UDP-N-acetyl-alpha-D-mannosamine + 2 NAD+ + H2O = UDP-N-acetyl-alpha-D-mannosaminuronate + 2 NADH + 2 H+.
89715	tRNA m6t6A37 methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + tRNA containing N6-threonylcarbamoyladenosine = S-adenosyl-L-homocysteine + tRNA containing N6-methylthreonylcarbamoyladenosine.
89716	Pip2-Oaf1 complex	C	A heterodimeric complex consisting of Zn(2)Cys(6) containing transcription factors Pip2 and Oaf1. It binds to the oleate response element (ORE), found in the promoters of fatty acid-inducible genes in Saccharomyces where, in the presence of oleate this bound complex activates the transcription of genes encoding peroxisomal proteins.
89717	spanning component of membrane	C	The component of a membrane consisting of gene products and protein complexes that have some part that spans both leaflets of the membrane.
89718	amino acid import across plasma membrane	P	The directed movement of an amino acid from outside of a cell, across the plasma membrane and into the cytosol.
89719	RHG protein domain binding	F	Interacting selectively and non-covalently with an RHG (reaper/hid/grimm) domain/motif (AKA iap binding motif).
89720	caspase binding	F	Interacting selectively and non-covalently with a caspase family protein.
89721	phosphoenolpyruvate transmembrane transporter activity	F	Enables the transfer of a phosphoenolpyruvate from one side of a membrane to the other.
89722	phosphoenolpyruvate transmembrane transport	P	The directed movement of phosphoenolpytuvate across a membrane.
90001	replication fork arrest at tRNA locus	P	A process that impedes the progress of the DNA replication fork at natural replication fork pausing sites within the eukaryotic tRNA transcription unit.
90002	establishment of protein localization to plasma membrane	P	The directed movement of a protein to a specific location in the plasma membrane.
90003	regulation of establishment of protein localization to plasma membrane	P	Any process that modulates the frequency, rate or extent of the directed movement of a protein to a specific location in the plasma membrane.
90004	positive regulation of establishment of protein localization to plasma membrane	P	Any process that increases the frequency, rate or extent of the directed movement of a protein to a specific location in the plasma membrane.
90005	negative regulation of establishment of protein localization to plasma membrane	P	Any process that decreases the frequency, rate or extent of the directed movement of a protein to a specific location in the plasma membrane.
90006	regulation of linear element assembly	P	Any process that modulates the rate, frequency or extent of linear element assembly. Linear element assembly is the cell cycle process in which a proteinaceous scaffold, related to the synaptonemal complex, is assembled in association with S. pombe chromosomes during meiotic prophase.
90008	hypoblast development	P	The process whose specific outcome is the progression of the hypoblast over time, from its formation to the mature structure. The hypoblast is a tissue formed from the inner cell mass that lies beneath the epiblast and gives rise to extraembryonic endoderm.
90009	primitive streak formation	P	The developmental process pertaining to the initial formation of the primitive streak from unspecified parts. The primitive streak is a ridge of cells running along the midline of the embryo where the mesoderm ingresses. It defines the anterior-posterior axis.
90010	transforming growth factor beta receptor signaling pathway involved in primitive streak formation	P	A series of molecular signals initiated by the binding of an extracellular ligand to a transforming growth factor beta receptor on the surface of a target cell, which contributes to the formation of the primitive streak.
90011	Wnt signaling pathway involved in primitive streak formation	P	The series of molecular signals initiated by binding of Wnt protein to a frizzled family receptor on the surface of the target cell and ending with a change in transcription of target genes that contribute to the formation of the primitive streak.
90012	negative regulation of transforming growth factor beta receptor signaling pathway involved in primitive streak formation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of any TGF-beta receptor signaling pathway that contributes to the formation of the primitive streak.
90013	regulation of transforming growth factor beta receptor signaling pathway involved in primitive streak formation	P	Any process that modulates the frequency, rate or extent of any TGF-beta receptor signaling pathway that contributes to the formation of the primitive streak.
90014	leaflet formation	P	The developmental process pertaining to the initial formation of a leaflet from unspecified parts. A leaflet is one of the ultimate segments of a compound leaf.
90015	positive regulation of leaflet formation by auxin mediated signaling pathway	P	Any process that increases the frequency, rate or extent of leaflet formation as a result of the series of molecular signals generated in response to detection of auxin.
90016	regulation of leaflet formation	P	Any process that modulates the frequency, rate or extent of leaflet formation.
90017	anterior neural plate formation	P	The formation of anterior end of the flat, thickened layer of ectodermal cells known as the neural plate.
90018	posterior neural plate formation	P	The formation of posterior end of the flat, thickened layer of ectodermal cells known as the neural plate.
90019	regulation of transcription involved in anterior neural plate formation	P	Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter contributing to the formation of the anterior neural plate.
90020	regulation of transcription involved in posterior neural plate formation	P	Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter contributing to the formation of the posterior neural plate.
90021	positive regulation of posterior neural plate formation by Wnt signaling pathway	P	The series of molecular signals initiated by binding of Wnt protein to a frizzled family receptor on the surface of the target cell and increasing the rate or extent of posterior neural plate formation.
90022	regulation of neutrophil chemotaxis	P	Any process that modulates the frequency, rate, or extent of neutrophil chemotaxis. Neutrophil chemotaxis is the directed movement of a neutrophil cell, the most numerous polymorphonuclear leukocyte found in the blood, in response to an external stimulus, usually an infection or wounding.
90023	positive regulation of neutrophil chemotaxis	P	Any process that increases the frequency, rate, or extent of neutrophil chemotaxis. Neutrophil chemotaxis is the directed movement of a neutrophil cell, the most numerous polymorphonuclear leukocyte found in the blood, in response to an external stimulus, usually an infection or wounding.
90024	negative regulation of neutrophil chemotaxis	P	Any process that decreases the frequency, rate, or extent of neutrophil chemotaxis. Neutrophil chemotaxis is the directed movement of a neutrophil cell, the most numerous polymorphonuclear leukocyte found in the blood, in response to an external stimulus, usually an infection or wounding.
90025	regulation of monocyte chemotaxis	P	Any process that modulates the frequency, rate, or extent of monocyte chemotaxis.
90026	positive regulation of monocyte chemotaxis	P	Any process that increases the frequency, rate, or extent of monocyte chemotaxis.
90027	negative regulation of monocyte chemotaxis	P	Any process that decreases the frequency, rate, or extent of monocyte chemotaxis.
90028	positive regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion	P	Any process that increases the frequency, rate or extent of pheromone-dependent signal transduction during conjugation with cellular fusion, a signal transduction process resulting in the relay, amplification or dampening of a signal generated in response to pheromone exposure in organisms that undergo conjugation with cellular fusion.
90029	negative regulation of pheromone-dependent signal transduction involved in conjugation with cellular fusion	P	Any process that decreases the frequency, rate or extent of pheromone-dependent signal transduction during conjugation with cellular fusion, a signal transduction process resulting in the relay, amplification or dampening of a signal generated in response to pheromone exposure in organisms that undergo conjugation with cellular fusion.
90030	regulation of steroid hormone biosynthetic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroid hormones,compounds with a 1, 2, cyclopentanoperhydrophenanthrene nucleus that act as hormones.
90031	positive regulation of steroid hormone biosynthetic process	P	Any process that increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroid hormones,compounds with a 1, 2, cyclopentanoperhydrophenanthrene nucleus that act as hormones.
90032	negative regulation of steroid hormone biosynthetic process	P	Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of steroid hormones,compounds with a 1, 2, cyclopentanoperhydrophenanthrene nucleus that act as hormones.
90033	positive regulation of filamentous growth	P	Any process that increases the frequency, rate or extent of the process in which a multicellular organism or a group of unicellular organisms grow in a threadlike, filamentous shape.
90034	regulation of chaperone-mediated protein complex assembly	P	Any process that modulates the frequency, rate, or extent of chaperone-mediated protein complex assembly. Chaperone-mediated protein complex assembly is the aggregation, arrangement and bonding together of a set of components to form a protein complex, mediated by chaperone molecules that do not form part of the finished complex.
90035	positive regulation of chaperone-mediated protein complex assembly	P	Any process that increases the frequency, rate, or extent of chaperone-mediated protein complex assembly. Chaperone-mediated protein complex assembly is the aggregation, arrangement and bonding together of a set of components to form a protein complex, mediated by chaperone molecules that do not form part of the finished complex.
90036	regulation of protein kinase C signaling	P	Any process that modulates the frequency, rate, or extent of a series of reactions, mediated by the intracellular serine/threonine kinase protein kinase C, which occurs as a result of a single trigger reaction or compound.
90037	positive regulation of protein kinase C signaling	P	Any process that increases the frequency, rate, or extent of a series of reactions, mediated by the intracellular serine/threonine kinase protein kinase C, which occurs as a result of a single trigger reaction or compound.
90038	negative regulation of protein kinase C signaling	P	Any process that decreases the frequency, rate, or extent of a series of reactions, mediated by the intracellular serine/threonine kinase protein kinase C, which occurs as a result of a single trigger reaction or compound.
90042	tubulin deacetylation	P	The removal of an acetyl group from tubulin. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid.
90043	regulation of tubulin deacetylation	P	Any process that modulates the frequency, rate or extent of tubulin deacetylation. Tubulin deacetylation is the removal of an acetyl group from a protein amino acid.
90044	positive regulation of tubulin deacetylation	P	Any process that increases the frequency, rate or extent of tubulin deacetylation. Tubulin deacetylation is the removal of an acetyl group from a protein amino acid.
90045	positive regulation of deacetylase activity	P	Any process that activates or increases the frequency, rate or extent of deacetylase activity, the catalysis of the hydrolysis of an acetyl group or groups from a substrate molecule.
90049	regulation of cell migration involved in sprouting angiogenesis	P	Any process that modulates the frequency, rate or extent of cell migration involved in sprouting angiogenesis. Cell migration involved in sprouting angiogenesis is the orderly movement of endothelial cells into the extracellular matrix in order to form new blood vessels contributing to the process of sprouting angiogenesis.
90050	positive regulation of cell migration involved in sprouting angiogenesis	P	Any process that increases the frequency, rate or extent of cell migration involved in sprouting angiogenesis. Cell migration involved in sprouting angiogenesis is the orderly movement of endothelial cells into the extracellular matrix in order to form new blood vessels contributing to the process of sprouting angiogenesis.
90051	negative regulation of cell migration involved in sprouting angiogenesis	P	Any process that decreases the frequency, rate or extent of cell migration involved in sprouting angiogenesis. Cell migration involved in sprouting angiogenesis is the orderly movement of endothelial cells into the extracellular matrix in order to form new blood vessels contributing to the process of sprouting angiogenesis.
90052	regulation of chromatin silencing at centromere	P	Any process that modulates the frequency, rate or extent of chromatin silencing at the centromere. Chromatin silencing at the centromere is the repression of transcription of centromeric DNA by altering the structure of chromatin.
90053	positive regulation of chromatin silencing at centromere	P	Any process that increases the frequency, rate or extent of chromatin silencing at the centromere. Chromatin silencing at the centromere is the repression of transcription of centromeric DNA by altering the structure of chromatin.
90054	regulation of chromatin silencing at silent mating-type cassette	P	Any process that modulates the frequency, rate, or extent of chromatin silencing at silent mating-type cassette. Chromatin silencing at silent mating-type cassette is the repression of transcription at silent mating-type loci by altering the structure of chromatin.
90055	positive regulation of chromatin silencing at silent mating-type cassette	P	Any process that increases the frequency, rate, or extent of chromatin silencing at silent mating-type cassette. Chromatin silencing at silent mating-type cassette is the repression of transcription at silent mating-type loci by altering the structure of chromatin.
90056	regulation of chlorophyll metabolic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving chlorophyll.
90057	root radial pattern formation	P	The radial pattern formation process that results in the formation of the different tissues of the root around its radial axis.
90058	metaxylem development	P	The process whose specific outcome is the progression of the metaxylem over time, from its formation to the mature structure. The metaxylem is the part of the primary xylem that differentiates after the protoxylem and before the secondary xylem, if any of the latter is formed.
90059	protoxylem development	P	The process whose specific outcome is the progression of the protoxylem over time, from its formation to the mature structure. The protoxylem comprises the first formed elements of the primary xylem.
90060	regulation of metaxylem development	P	Any process that modulates the frequency, rate, or extent of metaxylem development. Metaxylem development is the process whose specific outcome is the progression of the metaxylem over time, from its formation to the mature structure. The metaxylem is the part of the primary xylem that differentiates after the protoxylem and before the secondary xylem, if any of the latter is formed.
90062	regulation of trehalose metabolic process	P	Any process that modulates the frequency, rate or extent of trehalose metabolism, the chemical reactions and pathways involving trehalose, a disaccharide isomeric with sucrose and obtained from certain lichens and fungi.
90063	positive regulation of microtubule nucleation	P	Any process that increases the rate, frequency or extent of microtubule nucleation. Microtubule nucleation is the 'de novo' formation of a microtubule, in which tubulin heterodimers form metastable oligomeric aggregates, some of which go on to support formation of a complete microtubule. Microtubule nucleation usually occurs from a specific site within a cell.
90064	activation of microtubule nucleation	P	Any process that starts the inactive process of microtubule nucleation. Microtubule nucleation is the 'de novo' formation of a microtubule, in which tubulin heterodimers form metastable oligomeric aggregates, some of which go on to support formation of a complete microtubule. Microtubule nucleation usually occurs from a specific site within a cell.
90065	regulation of production of siRNA involved in RNA interference	P	Any process that modulates the frequency, rate or extent of the production of siRNA, the cleavage of double-stranded RNA to form small interfering RNA molecules (siRNAs) of 21-23 nucleotides, in the context of RNA interference.
90066	regulation of anatomical structure size	P	Any process that modulates the size of an anatomical structure.
90067	regulation of thalamus size	P	Any process that modulates the size of the thalamus. The thalamus is a part of the diencephalon that is composed of the dorsal thalamus and the ventral thalamus.
90068	positive regulation of cell cycle process	P	Any process that increases the rate, frequency or extent of a cellular process that is involved in the progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events.
90069	regulation of ribosome biogenesis	P	Any process that modulates the rate, frequency or extent of ribosome biogenesis. Ribosome biogenesis is the cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits.
90070	positive regulation of ribosome biogenesis	P	Any process that increases the rate, frequency or extent of ribosome biogenesis. Ribosome biogenesis is the cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits.
90071	negative regulation of ribosome biogenesis	P	Any process that decreases the rate, frequency or extent of ribosome biogenesis. Ribosome biogenesis is the cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of ribosome subunits.
90073	positive regulation of protein homodimerization activity	P	Any process that increases the frequency, rate or extent of protein homodimerization, interacting selectively with an identical protein to form a homodimer.
90074	negative regulation of protein homodimerization activity	P	Any process that decreases the frequency, rate or extent of protein homodimerization, interacting selectively with an identical protein to form a homodimer.
90075	relaxation of muscle	P	A process in which the extent of muscle contraction is reduced. Muscle relaxation can involve a number of processes including the removal of calcium from the cytoplasm to the sarcoplasmic reticulum lumen through the action of Ca2+ ATPases. In some muscles, calcium-independent pathways also play a role in muscle relaxation by decreasing the phosphorylation state of myosin light chain.
90076	relaxation of skeletal muscle	P	A process in which the extent of skeletal muscle tissue contraction is reduced. Muscle relaxation involves the removal of calcium from the cytoplasm to the sarcoplasmic reticulum lumen through the action of Ca2+ ATPases.
90077	foam cell differentiation	P	The process in which a relatively unspecialized cell acquires the specialized features of a foam cell. A foam cell is a type of cell containing lipids in small vacuoles and typically seen in atherosclerotic lesions, as well as other conditions.
90078	smooth muscle derived foam cell differentiation	P	The process in which a smooth muscle cell acquires the specialized features of a foam cell. A foam cell is a type of cell containing lipids in small vacuoles and typically seen in atherosclerotic lesions, as well as other conditions.
90079	translation regulator activity, nucleic acid binding	F	Any selective and non-covalent interaction with a nucleic acid involved in the initiation, activation, perpetuation, repression or termination of polypeptide synthesis at the ribosome.
90080	positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway	P	The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands resulting in an increase in the rate or frequency of a MAPKKK cascade.
90081	regulation of heart induction by regulation of canonical Wnt signaling pathway	P	Any process that modulates the rate, frequency or extent of canonical Wnt signaling pathway that regulates heart induction. Canonical Wnt signaling pathway involved in heart induction is the series of molecular signals initiated by binding of Wnt protein to a frizzled family receptor on the surface of the target cell, followed by relaying of the signal via beta-catenin, and ending with a change in transcription of target genes.
90082	positive regulation of heart induction by negative regulation of canonical Wnt signaling pathway	P	Any process that decreases the rate, frequency or extent of canonical Wnt signaling pathway that positively regulates heart induction. Canonical Wnt signaling pathway involved in heart induction is the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes.
90083	regulation of inclusion body assembly	P	Any process that modulates the rate, frequency, or extent of inclusion body assembly. Inclusion body assembly is the aggregation, arrangement and bonding together of a set of components to form an inclusion body.
90084	negative regulation of inclusion body assembly	P	Any process that decreases the rate, frequency, or extent of inclusion body assembly. Inclusion body assembly is the aggregation, arrangement and bonding together of a set of components to form an inclusion body.
90085	regulation of protein deubiquitination	P	Any process that modulates the frequency, rate or extent of protein deubiquitination. Protein deubiquitination is the removal of one or more ubiquitin groups from a protein.
90086	negative regulation of protein deubiquitination	P	Any process that decreases the frequency, rate or extent of protein deubiquitination. Protein deubiquitination is the removal of one or more ubiquitin groups from a protein.
90087	regulation of peptide transport	P	Any process that modulates the frequency, rate or extent of the directed movement of peptides, compounds of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
90088	regulation of oligopeptide transport	P	Any process that modulates the frequency, rate or extent of the directed movement of oligopeptides into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Oligopeptides are molecules that contain a small number (2 to 20) of amino-acid residues connected by peptide linkages.
90089	regulation of dipeptide transport	P	Any process that modulates the rate, frequency or extent of dipeptide transport. Dipeptide transport is the directed movement of a dipeptide, a combination of two amino acids by means of a peptide (-CO-NH-) link, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
90090	negative regulation of canonical Wnt signaling pathway	P	Any process that decreases the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin, the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes.
90091	positive regulation of extracellular matrix disassembly	P	Any process that increases the rate, frequency or extent of extracellular matrix disassembly. Extracellular matrix disassembly is a process that results in the breakdown of the extracellular matrix.
90092	regulation of transmembrane receptor protein serine/threonine kinase signaling pathway	P	Any process that modulates the rate, frequency, or extent of the series of molecular signals generated as a consequence of a transmembrane receptor serine/threonine kinase binding to its physiological ligand.
90093	regulation of fungal-type cell wall beta-glucan biosynthetic process	P	Any process that modulates the frequency, rate or extent of fungal-type cell wall beta-glucan biosynthesis, the chemical reactions and pathways resulting in the formation of beta-glucans, compounds composed of glucose residues linked by beta-D-glucosidic bonds, found in the walls of fungal cells.
90094	metanephric cap mesenchymal cell proliferation involved in metanephros development	P	The multiplication or reproduction of metanephric cap mesenchymal cells, resulting in the expansion of the cell population. A metanephric cap mesenchymal cell is a mesenchymal cell that has condensed with other mesenchymal cells surrounding the ureteric bud tip.
90095	regulation of metanephric cap mesenchymal cell proliferation	P	Any process that modulates the frequency, rate, or extent of metanephric cap mesenchymal cell proliferation. Metanephric cap mesenchymal cell proliferation is the multiplication or reproduction of metanephric cap mesenchymal cells, resulting in the expansion of the cell population. A metanephric cap mesenchymal cell is a mesenchymal cell that has condensed with other mesenchymal cells surrounding the ureteric bud tip.
90096	positive regulation of metanephric cap mesenchymal cell proliferation	P	Any process that increases the frequency, rate, or extent of metanephric cap mesenchymal cell proliferation. Metanephric cap mesenchymal cell proliferation is the multiplication or reproduction of metanephric cap mesenchymal cells, resulting in the expansion of the cell population. A metanephric cap mesenchymal cell is a mesenchymal cell that has condensed with other mesenchymal cells surrounding the ureteric bud tip.
90097	regulation of decapentaplegic signaling pathway	P	Any process that modulates the frequency, rate, or extent of the decapentaplegic signaling pathway. The decapentaplegic signaling pathway is the series of molecular signals generated as a consequence of the signal decapentaplegic binding to one of its physiological receptors.
90098	positive regulation of decapentaplegic signaling pathway	P	Any process that increases the frequency, rate, or extent of the decapentaplegic signaling pathway. The decapentaplegic signaling pathway is the series of molecular signals generated as a consequence of the signal decapentaplegic binding to one of its physiological receptors.
90099	negative regulation of decapentaplegic signaling pathway	P	Any process that decreases the frequency, rate, or extent of the decapentaplegic signaling pathway. The decapentaplegic signaling pathway is the series of molecular signals generated as a consequence of the signal decapentaplegic binding to one of its physiological receptors.
90100	positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway	P	Any process that increases the rate, frequency, or extent of the series of molecular signals generated as a consequence of a transmembrane receptor serine/threonine kinase binding to its physiological ligand.
90101	negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway	P	Any process that decreases the rate, frequency, or extent of the series of molecular signals generated as a consequence of a transmembrane receptor serine/threonine kinase binding to its physiological ligand.
90102	cochlea development	P	The progression of the cochlea over time from its formation to the mature structure. The cochlea is the snail-shaped portion of the inner ear that is responsible for the detection of sound.
90103	cochlea morphogenesis	P	The process in which the cochlea is generated and organized.
90104	pancreatic epsilon cell differentiation	P	The process in which relatively unspecialized cells acquire specialized structural and functional features of a pancreatic epsilon cell. A pancreatic epsilon cell is a cell in the pancreas that secretes ghrelin.
90105	pancreatic E cell development	P	The process whose specific outcome is the progression of a pancreatic E cell over time, from its formation to the mature structure.
90106	pancreatic E cell fate commitment	P	The commitment of a cell to a pancreatic E cell fate and its capacity to differentiate into a pancreatic E cell.
90107	regulation of high-density lipoprotein particle assembly	P	Any process that modulates the frequency, rate, or extent of high-density lipoprotein particle assembly. High-density lipoprotein particle assembly is the aggregation and arrangement of proteins and lipids to form a high-density lipoprotein particle.
90108	positive regulation of high-density lipoprotein particle assembly	P	Any process that increases the frequency, rate, or extent of high-density lipoprotein particle assembly. High-density lipoprotein particle assembly is the aggregation and arrangement of proteins and lipids to form a high-density lipoprotein particle.
90109	regulation of cell-substrate junction assembly	P	Any process that modulates the rate, frequency, or extent of cell-substrate junction assembly. Cell-substrate junction assembly is the aggregation, arrangement and bonding together of a set of components to form a junction between a cell and its substrate.
90110	cargo loading into COPII-coated vesicle	P	The formation of a macromolecular complex between the COPII coat proteins and proteins and/or lipoproteins that are going to be transported by the COPII vesicle to the Golgi.
90111	regulation of COPII vesicle uncoating	P	Any process that modulates the frequency, rate or extent of COPII vesicle uncoating, the process in which COPII vesicle coat proteins are disassembled, and released.
90112	COPII vesicle uncoating	P	The process in which COPII vesicle coat proteins are disassembled, and released.
90113	regulation of ER to Golgi vesicle-mediated transport by GTP hydrolysis	P	The GTP hydrolysis process that modulates the rate, frequency, or extent of ER to Golgi vesicle-mediated transport, the directed movement of substances from the endoplasmic reticulum (ER) to the Golgi, mediated by COP II vesicles.
90114	COPII-coated vesicle budding	P	The evagination of an endoplasmic reticulum membrane, resulting in formation of a COPII-coated vesicle.
90115	C-5 methylation on cytosine involved in chromatin silencing	P	The covalent transfer of a methyl group to C-5 of cytosine in a DNA molecule that contributes to chromatin silencing.
90116	C-5 methylation of cytosine	P	The covalent transfer of a methyl group to C-5 of cytosine in a DNA molecule.
90117	endosome to lysosome transport of low-density lipoprotein particle	P	The directed movement of low-density lipoprotein particle from endosomes to lysosomes.
90118	receptor-mediated endocytosis involved in cholesterol transport	P	A receptor-mediated endocytosis process involved in intracellular cholesterol transport.
90119	vesicle-mediated cholesterol transport	P	The directed movement of cholesterol, cholest-5-en-3-beta-ol, or cholesterol-containing compounds, by membrane-bounded vesicles.
90120	lysosome to ER cholesterol transport	P	The directed movement of cholesterol, cholest-5-en-3-beta-ol, or cholesterol-containing compounds, from the lysosome to the endoplasmic reticulum.
90121	low-density lipoprotein particle disassembly involved in cholesterol transport	P	The disassembly into constituent parts of the low-density lipoprotein particle in the lysosome that contributes to cholesterol transport.
90122	cholesterol ester hydrolysis involved in cholesterol transport	P	The cholesterol metabolic process in which cholesterol esters are hydrolyzed into free fatty acids and cholesterol in the lysosome that contributes to intracellular cholesterol transport.
90123	lysosomal glycocalyx	C	The polysaccharide-based coating on the inner side of a lysosomal membrane that protects it from digestion by lysosomal enzymes.
90124	N-4 methylation of cytosine	P	The covalent transfer of a methyl group to N-4 of cytosine in a DNA molecule.
90125	cell-cell adhesion involved in synapse maturation	P	The attachment of the pre-synaptic cell to the post-synaptic cell via adhesion molecules that contributes to synapse maturation.
90126	protein complex assembly involved in synapse maturation	P	The aggregation, arrangement and bonding together of a set of components to form a protein complex that contributes to synapse maturation.
90127	positive regulation of synapse maturation by synaptic transmission	P	Any process that increases the extent of synaptic maturation as a result of the communication from a pre-synaptic cell to a post-synaptic cell across a synapse.
90128	regulation of synapse maturation	P	Any process that modulates the extent of synapse maturation, the process that organizes a synapse so that it attains its fully functional state.
90129	positive regulation of synapse maturation	P	Any process that increases the extent of synapse maturation, the process that organizes a synapse so that it attains its fully functional state.
90130	tissue migration	P	The process in which the population of cells that make up a tissue undergo directed movement.
90131	mesenchyme migration	P	The process in which the population of cells that make up a mesenchyme undergo directed movement.
90132	epithelium migration	P	The process in which the population of cells that make up an epithelium undergo directed movement.
90133	mesendoderm migration	P	The process in which the population of cells that make up a mesendoderm undergo directed movement. The mesendoderm is the epithelial tissue that gives rise to both mesoderm and endoderm.
90134	cell migration involved in mesendoderm migration	P	The orderly movement of epithelial cells from one site to another that contributes to the migration of mesendodermal tissue.
90135	actin filament branching	P	The formation of daughter actin filament branches at an angle on the sides of preexisting mother filaments.
90136	epithelial cell-cell adhesion	P	The attachment of an epithelial cell to another epithelial cell via adhesion molecules.
90137	epithelial cell-cell adhesion involved in epithelium migration	P	The attachment of an epithelial cell to another epithelial cell via adhesion molecules that contributes to epithelium migration.
90138	regulation of actin cytoskeleton organization by cell-cell adhesion	P	Any cell-cell adhesion process that modulates the formation, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins.
90139	mitochondrial DNA packaging	P	Any process in which mitochondrial DNA and associated proteins are formed into a compact, orderly structure.
90140	regulation of mitochondrial fission	P	Any process that modulates the rate, frequency or extent of mitochondrial fission. Mitochondrial fission is the division of a mitochondrion within a cell to form two or more separate mitochondrial compartments.
90141	positive regulation of mitochondrial fission	P	Any process that increases the rate, frequency or extent of mitochondrial fission. Mitochondrial fission is the division of a mitochondrion within a cell to form two or more separate mitochondrial compartments.
90143	nucleoid organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nucleoid. The nucleoid is the region of a bacterial cell, virion, mitochondrion or chloroplast to which the DNA is confined.
90144	mitochondrial nucleoid organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the mitochondrial nucleoid. The mitochondrial nucleoid is the region of a mitochondrion to which the DNA is confined.
90145	mitochondrial nucleoid organization involved in mitochondrial fission	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the mitochondrial nucleoid that contributes to mitochondrial division.
90146	establishment of mitochondrion localization involved in mitochondrial fission	P	The directed movement of mitochondria to the correct region of the cell that contributes to the process of mitochondrial fission.
90147	regulation of establishment of mitochondrion localization involved in mitochondrial fission	P	Any process that modulates the frequency, rate or extent of the directed movement of mitochondria to the correct region of the cell that contributes to the process of mitochondrial fission.
90148	membrane fission	P	A process that is carried out at the cellular level which results in the separation of a single continuous membrane into two membranes.
90149	mitochondrial membrane fission	P	A process that is carried out at the cellular level which results in the separation of a single continuous mitochondrial membrane into two membranes and contributes to mitochondrial fission.
90150	establishment of protein localization to membrane	P	The directed movement of a protein to a specific location in a membrane.
90151	establishment of protein localization to mitochondrial membrane	P	The directed movement of a protein to a specific location in the mitochondrial membrane.
90152	establishment of protein localization to mitochondrial membrane involved in mitochondrial fission	P	The directed movement of a protein to a specific location in the mitochondrial membrane that contributes to mitochondrial fission.
90153	regulation of sphingolipid biosynthetic process	P	Any process that modulates the rate, frequency or extent of sphingolipid biosynthesis. Sphingolipid biosynthesis is the chemical reactions and pathways resulting in the formation of sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid).
90154	positive regulation of sphingolipid biosynthetic process	P	Any process that increases the rate, frequency or extent of sphingolipid biosynthesis. Sphingolipid biosynthesis is the chemical reactions and pathways resulting in the formation of sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid).
90155	negative regulation of sphingolipid biosynthetic process	P	Any process that decreases the rate, frequency or extent of sphingolipid biosynthesis. Sphingolipid biosynthesis is the chemical reactions and pathways resulting in the formation of sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid).
90156	cellular sphingolipid homeostasis	P	Any biological process involved in the maintenance of an internal steady state of sphingolipids at the level of the cell.
90157	negative regulation of sphingolipid biosynthesis involved in cellular sphingolipid homeostasis	P	Any process that decreases the rate, frequency or extent of sphingolipid biosynthesis that contributes to the maintenance of an internal equilibrium of sphingolipids at the level of the cell.
90158	endoplasmic reticulum membrane organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an endoplasmic reticulum membrane.
90159	sphingolipid biosynthesis involved in endoplasmic reticulum membrane organization	P	The chemical reactions and pathways resulting in the formation of sphingolipids that contributes to endoplasmic reticulum membrane organization.
90160	Golgi to lysosome transport	P	The directed movement of substances from the Golgi to lysosomes.
90161	Golgi ribbon formation	P	The formation of a continuous ribbon of interconnected Golgi stacks of flat cisternae.
90162	establishment of epithelial cell polarity	P	The specification and formation of anisotropic intracellular organization of an epithelial cell.
90163	establishment of epithelial cell planar polarity	P	The specification and formation of the polarity of an epithelial cell along the plane of the epithelial tissue.
90164	asymmetric Golgi ribbon formation	P	The asymmetric formation of a continuous ribbon of interconnected Golgi stacks of flat cisternae that contributes to the establishment of epithelial cell polarity.
90165	regulation of secretion by asymmetric Golgi ribbon formation	P	The asymmetric formation of a continuous ribbon of interconnected Golgi stacks of flat cisternae that modulates the controlled release of a substance from a polarized epithelial cell.
90166	Golgi disassembly	P	A cellular process that results in the breakdown of a Golgi apparatus that contributes to Golgi inheritance.
90167	Golgi distribution to daughter cells	P	Any process in which disassembled Golgi vesicles are localized into daughter cells upon cell division.
90168	Golgi reassembly	P	The reformation of the Golgi following its breakdown and partitioning contributing to Golgi inheritance.
90169	regulation of spindle assembly	P	Any process that modulates the rate, frequency or extent of spindle assembly. Spindle assembly is the aggregation, arrangement and bonding together of a set of components to form the spindle, the array of microtubules and associated molecules that serves to move duplicated chromosomes apart.
90170	regulation of Golgi inheritance	P	Any process that modulates the rate, frequency or extent of Golgi inheritance. Golgi inheritance is the partitioning of Golgi apparatus between daughter cells at cell division.
90171	chondrocyte morphogenesis	P	The process in which the structures of a chondrocyte are generated and organized. This process occurs while the initially relatively unspecialized cell is acquiring the specialized features of a chondrocyte.
90172	microtubule cytoskeleton organization involved in homologous chromosome segregation	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins that contributes to chromosomal pairing and precedes synapsis.
90173	regulation of synaptonemal complex assembly	P	Any process that modulates the frequency, rate or extent of synaptonemal complex assembly. Synaptonemal complex assembly is the cell cycle process in which the synaptonemal complex, a structure that holds paired chromosomes together during prophase I of meiosis and that promotes genetic recombination, is formed.
90174	organelle membrane fusion	P	The joining of two lipid bilayers to form a single organelle membrane.
90175	regulation of establishment of planar polarity	P	Any process that modulates the rate, frequency or extent of the establishment of planar polarity, the coordinated organization of groups of cells in a tissue, such that they all orient to similar coordinates.
90176	microtubule cytoskeleton organization involved in establishment of planar polarity	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising microtubules and their associated proteins and contributes to the establishment of planar polarity.
90177	establishment of planar polarity involved in neural tube closure	P	Coordinated organization of groups of cells in the plane of an epithelium that contributes to the closure of the neural tube.
90178	regulation of establishment of planar polarity involved in neural tube closure	P	Any process that modulates the rate, frequency, or extent of the establishment of planar polarity involved in neural tube closure, the coordinated organization of groups of cells in the plane of an epithelium that contributes to the closure of the neural tube.
90179	planar cell polarity pathway involved in neural tube closure	P	The series of molecular signals initiated by binding of a Wnt protein to a receptor on the surface of the target cell where activated receptors signal via downstream effectors that modulates the establishment of planar polarity contributing to neural tube closure.
90180	positive regulation of thiamine biosynthetic process	P	Any process that increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of thiamine.
90181	regulation of cholesterol metabolic process	P	Any process that modulates the rate, frequency, or extent of cholesterol metabolism, the chemical reactions and pathways involving cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones.
90182	regulation of secretion of lysosomal enzymes	P	Any process that modulates the rate, frequency or extent of secretion of lysosomal enzymes, the controlled release of lysosomal enzymes by a cell.
90183	regulation of kidney development	P	Any process that modulates the rate, frequency or extent of kidney development. Kidney development is the process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure. The kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine.
90184	positive regulation of kidney development	P	Any process that increases the rate, frequency or extent of kidney development. Kidney development is the process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure. The kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine.
90185	negative regulation of kidney development	P	Any process that decreases the rate, frequency or extent of kidney development. Kidney development is the process whose specific outcome is the progression of the kidney over time, from its formation to the mature structure. The kidney is an organ that filters the blood and excretes the end products of body metabolism in the form of urine.
90186	regulation of pancreatic juice secretion	P	Any process that modulates the rate, frequency or extent of pancreatic juice secretion, the regulated release of pancreatic juice by the exocrine pancreas into the upper part of the intestine.
90187	positive regulation of pancreatic juice secretion	P	Any process that increases the rate, frequency or extent of pancreatic juice secretion, the regulated release of pancreatic juice by the exocrine pancreas into the upper part of the intestine.
90188	negative regulation of pancreatic juice secretion	P	Any process that decreases the rate, frequency or extent of pancreatic juice secretion, the regulated release of pancreatic juice by the exocrine pancreas into the upper part of the intestine.
90189	regulation of branching involved in ureteric bud morphogenesis	P	Any process that modulates the rate, frequency or extent of branching involved in ureteric bud morphogenesis, the process in which the branching structure of the ureteric bud is generated and organized. The ureteric bud is an epithelial tube that grows out from the metanephric duct. The bud elongates and branches to give rise to the ureter and kidney collecting tubules.
90190	positive regulation of branching involved in ureteric bud morphogenesis	P	Any process that increases the rate, frequency or extent of branching involved in ureteric bud morphogenesis, the process in which the branching structure of the ureteric bud is generated and organized. The ureteric bud is an epithelial tube that grows out from the metanephric duct. The bud elongates and branches to give rise to the ureter and kidney collecting tubules.
90191	negative regulation of branching involved in ureteric bud morphogenesis	P	Any process that decreases the rate, frequency or extent of branching involved in ureteric bud morphogenesis, the process in which the branching structure of the ureteric bud is generated and organized. The ureteric bud is an epithelial tube that grows out from the metanephric duct. The bud elongates and branches to give rise to the ureter and kidney collecting tubules.
90192	regulation of glomerulus development	P	Any process that modulates the rate, frequency or extent of glomerulus development, the progression of the glomerulus over time from its initial formation until its mature state. The glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney.
90193	positive regulation of glomerulus development	P	Any process that increases the rate, frequency or extent of glomerulus development, the progression of the glomerulus over time from its initial formation until its mature state. The glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney.
90194	negative regulation of glomerulus development	P	Any process that decreases the rate, frequency or extent of glomerulus development, the progression of the glomerulus over time from its initial formation until its mature state. The glomerulus is a capillary tuft surrounded by Bowman's capsule in nephrons of the vertebrate kidney.
90195	chemokine secretion	P	The regulated release of chemokines from a cell.
90196	regulation of chemokine secretion	P	Any process that modulates the rate, frequency or extent of chemokine secretion, the regulated release of chemokines from a cell.
90197	positive regulation of chemokine secretion	P	Any process that increases the rate, frequency or extent of chemokine secretion, the regulated release of chemokines from a cell.
90198	negative regulation of chemokine secretion	P	Any process that decreases the rate, frequency or extent of chemokine secretion, the regulated release of chemokines from a cell.
90199	regulation of release of cytochrome c from mitochondria	P	Any process that modulates the rate, frequency or extent of release of cytochrome c from mitochondria, the process in which cytochrome c is enabled to move from the mitochondrial intermembrane space into the cytosol, which is an early step in apoptosis and leads to caspase activation.
90200	positive regulation of release of cytochrome c from mitochondria	P	Any process that increases the rate, frequency or extent of release of cytochrome c from mitochondria, the process in which cytochrome c is enabled to move from the mitochondrial intermembrane space into the cytosol, which is an early step in apoptosis and leads to caspase activation.
90201	negative regulation of release of cytochrome c from mitochondria	P	Any process that decreases the rate, frequency or extent of release of cytochrome c from mitochondria, the process in which cytochrome c is enabled to move from the mitochondrial intermembrane space into the cytosol, which is an early step in apoptosis and leads to caspase activation.
90202	gene looping	P	The formation and maintenance of DNA loops that juxtapose sequentially separated regions of RNA polymerase II-transcribed genes.
90203	transcriptional activation by promoter-terminator looping	P	The formation and maintenance of DNA loops that juxtapose the promoter and terminator regions of RNA polymerase II-transcribed genes and activate transcription from an RNA polymerase II promoter.
90204	protein localization to nuclear pore	P	A process in which a protein is transported to, or maintained in, a nuclear pore.
90205	positive regulation of cholesterol metabolic process	P	Any process that increases the rate, frequency, or extent of cholesterol metabolism, the chemical reactions and pathways involving cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones.
90206	negative regulation of cholesterol metabolic process	P	Any process that decreases the rate, frequency, or extent of cholesterol metabolism, the chemical reactions and pathways involving cholesterol, cholest-5-en-3 beta-ol, the principal sterol of vertebrates and the precursor of many steroids, including bile acids and steroid hormones.
90207	regulation of triglyceride metabolic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving triglyceride, any triester of glycerol.
90208	positive regulation of triglyceride metabolic process	P	Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving triglyceride, any triester of glycerol.
90209	negative regulation of triglyceride metabolic process	P	Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving triglyceride, any triester of glycerol.
90210	regulation of establishment of blood-brain barrier	P	Any process that modulates the rate, frequency or extent of the establishment of the blood-brain barrier, a selectively permeable structural and functional barrier that exists between the capillaries and the brain.
90211	positive regulation of establishment of blood-brain barrier	P	Any process that increases the rate, frequency or extent of the establishment of the blood-brain barrier, a selectively permeable structural and functional barrier that exists between the capillaries and the brain.
90212	negative regulation of establishment of blood-brain barrier	P	Any process that decreases the rate, frequency or extent of the establishment of the blood-brain barrier, a selectively permeable structural and functional barrier that exists between the capillaries and the brain.
90213	regulation of radial pattern formation	P	Any process that modulates the rate, frequency or extent of radial pattern formation, the regionalization process that results in defined areas around a point in which specific types of cell differentiation will occur.
90214	spongiotrophoblast layer developmental growth	P	The increase in size or mass of the spongiotrophoblast layer of the placenta where the increase in size or mass contributes to the progression of that layer over time from its formation to its mature state.
90215	regulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity	P	Any process that modulates the frequency, rate or extent of the catalysis of the reaction: ATP + 1-phosphatidyl-1D-myo-inositol 4-phosphate = ADP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate.
90216	positive regulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity	P	Any process that increases the frequency, rate or extent of the catalysis of the reaction: ATP + 1-phosphatidyl-1D-myo-inositol 4-phosphate = ADP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate.
90217	negative regulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity	P	Any process that decreases the frequency, rate or extent of the catalysis of the reaction: ATP + 1-phosphatidyl-1D-myo-inositol 4-phosphate = ADP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate.
90218	positive regulation of lipid kinase activity	P	Any process that increases the frequency, rate or extent of lipid kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a simple or complex lipid.
90219	negative regulation of lipid kinase activity	P	Any process that decreases the frequency, rate or extent of lipid kinase activity, the catalysis of the transfer of a phosphate group, usually from ATP, to a simple or complex lipid.
90220	chromosome localization to nuclear envelope involved in homologous chromosome segregation	P	The directed movement of a chromosome to the nuclear envelope that contributes to homologous chromosome segregation and precedes synapsis.
90221	mitotic spindle-templated microtubule nucleation	P	The 'de novo' formation of a microtubule, in which tubulin heterodimers form metastable oligomeric aggregates from within the mitotic spindle.
90222	centrosome-templated microtubule nucleation	P	The 'de novo' formation of a microtubule, in which tubulin heterodimers form metastable oligomeric aggregates from the centrosome.
90223	chromatin-templated microtubule nucleation	P	The 'de novo' formation of a microtubule, in which tubulin heterodimers form metastable oligomeric aggregates from chromatin.
90224	regulation of spindle organization	P	Any process that modulates the rate, frequency or extent of the assembly, arrangement of constituent parts, or disassembly of the microtubule spindle.
90225	regulation of spindle density	P	Any process that modulates the number of microtubules in a given region of the spindle.
90226	regulation of microtubule nucleation by Ran protein signal transduction	P	Any series of molecular signals in which a Ran GTPase relays one or more of the signals resulting in the modulation of the rate, frequency or extent of microtubule nucleation.
90227	regulation of red or far-red light signaling pathway	P	Any process that modulates the rate, frequency or extent of the red or far-red signaling pathway, the series of molecular signals initiated upon sensing by photoreceptor molecules of red light or far red light.
90228	positive regulation of red or far-red light signaling pathway	P	Any process that increases the rate, frequency or extent of the red or far-red signaling pathway, the series of molecular signals initiated upon sensing by photoreceptor molecules of red light or far red light.
90229	negative regulation of red or far-red light signaling pathway	P	Any process that decreases the rate, frequency or extent of the red or far-red signaling pathway, the series of molecular signals initiated upon sensing by photoreceptor molecules of red light or far red light.
90230	regulation of centromere complex assembly	P	Any process that modulates the rate, frequency, or extent of centromere complex assembly, the aggregation, arrangement and bonding together of proteins and centromeric DNA molecules to form a centromeric protein-DNA complex.
90231	regulation of spindle checkpoint	P	Any process that modulates the rate, frequency, or extent of the spindle checkpoint, a cell cycle checkpoint that delays the metaphase/anaphase transition until the spindle is correctly assembled and oriented, and chromosomes are attached to the spindle.
90232	positive regulation of spindle checkpoint	P	Any process that increases the rate, frequency, or extent of the spindle checkpoint, a cell cycle checkpoint that delays the metaphase/anaphase transition until the spindle is correctly assembled and oriented, and chromosomes are attached to the spindle.
90233	negative regulation of spindle checkpoint	P	Any process that decreases the rate, frequency, or extent of the spindle checkpoint, a cell cycle checkpoint that delays the metaphase/anaphase transition until the spindle is correctly assembled and oriented, and chromosomes are attached to the spindle.
90234	regulation of kinetochore assembly	P	Any process that modulates the rate, frequency, or extent of kinetochore assembly, the aggregation, arrangement and bonding together of a set of components to form the kinetochore, a multisubunit complex that is located at the centromeric region of DNA and provides an attachment point for the spindle microtubules.
90235	regulation of metaphase plate congression	P	Any process that modulates the rate, frequency, or extent of metaphase plate congression, the alignment of chromosomes at the metaphase plate, a plane halfway between the poles of the spindle.
90236	regulation of transcription from RNA polymerase II promoter involved in somitogenesis	P	Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that contributes to the formation of mesodermal clusters that are arranged segmentally along the anterior posterior axis of an embryo.
90237	regulation of arachidonic acid secretion	P	Any process that modulates the rate, frequency, or extent of arachidonic acid secretion, the controlled release of arachidonic acid from a cell or a tissue.
90238	positive regulation of arachidonic acid secretion	P	Any process that increases the rate, frequency, or extent of arachidonic acid secretion, the controlled release of arachidonic acid from a cell or a tissue.
90239	regulation of histone H4 acetylation	P	Any process that modulates the rate, frequency, or extent of histone H4 acetylation, the modification of histone H4 by the addition of an acetyl group.
90240	positive regulation of histone H4 acetylation	P	Any process that increases the rate, frequency, or extent of histone H4 acetylation, the modification of histone H4 by the addition of an acetyl group.
90241	negative regulation of histone H4 acetylation	P	Any process that decreases the rate, frequency, or extent of histone H4 acetylation, the modification of histone H4 by the addition of an acetyl group.
90242	retinoic acid receptor signaling pathway involved in somitogenesis	P	The series of molecular signals generated as a consequence of a retinoic acid receptor binding to one of its physiological ligands that contributes to somitogenesis.
90243	fibroblast growth factor receptor signaling pathway involved in somitogenesis	P	The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands that contributes to somitogenesis.
90244	Wnt signaling pathway involved in somitogenesis	P	The series of molecular signals initiated by binding of Wnt protein to a frizzled family receptor on the surface of the target cell and ending with a change in cell state that contributes to somitogenesis.
90245	axis elongation involved in somitogenesis	P	The developmental growth that results in the elongation of the rostral-caudal axis that contributes to somitogenesis.
90246	convergent extension involved in somitogenesis	P	The morphogenetic process in which a presomitic mesoderm narrows along the left-right axis and lengthens in the rostral-caudal axis contributing to somitogenesis.
90247	cell motility involved in somitogenic axis elongation	P	Any process involved in the controlled self-propelled movement of a cell that contributes to somitogenic axis elongation.
90248	cell migration involved in somitogenic axis elongation	P	The orderly movement of a presomitic mesoderm cell that contributes to somitogenic axis elongation.
90249	regulation of cell motility involved in somitogenic axis elongation	P	Any process that modulates the frequency, rate, or extent of the controlled self-propelled movement of a cell that contributes to somitogenic axis elongation.
90250	cell-cell adhesion involved in establishment of planar polarity	P	The attachment of one cell to another cell via adhesion molecules that contributes to the establishment of planar cell polarity.
90251	protein localization involved in establishment of planar polarity	P	Any process in which a protein is transported to, and/or maintained in, a specific location in a cell that contributes to the establishment of planar polarity.
90252	epithelium migration involved in imaginal disc-derived wing morphogenesis	P	The process in which the population of cells that make up a wing epithelium undergo directed movement and contribute to imaginal disc-derived morphogenesis.
90253	convergent extension involved in imaginal disc-derived wing morphogenesis	P	The morphogenetic process in which the wing epithelium narrows along one axis and lengthens in a perpendicular axis that contributes to imaginal disc-derived wing morphogenesis.
90254	cell elongation involved in imaginal disc-derived wing morphogenesis	P	The process in which a cell elongates and contributes to imaginal disc-derived wing morphogenesis.
90255	cell proliferation involved in imaginal disc-derived wing morphogenesis	P	The multiplication or reproduction of cells, resulting in the expansion of a cell population that contributes to imaginal disc-derived wing morphogenesis.
90256	regulation of cell proliferation involved in imaginal disc-derived wing morphogenesis	P	Any process that modulates the frequency, rate, or extent of the multiplication or reproduction of cells, resulting in the expansion of a cell population that contributes to imaginal disc-derived wing morphogenesis.
90257	regulation of muscle system process	P	Any process that modulates the frequency, rate or extent of a muscle system process, a multicellular organismal process carried out by any of the organs or tissues in a muscle system.
90258	negative regulation of mitochondrial fission	P	Any process that decreases the rate, frequency or extent of mitochondrial fission. Mitochondrial fission is the division of a mitochondrion within a cell to form two or more separate mitochondrial compartments.
90259	regulation of retinal ganglion cell axon guidance	P	Any process that modulates the frequency, rate, or extent of retinal ganglion cell axon guidance, the process in which the migration of an axon growth cone of a retinal ganglion cell (RGC) is directed to its target in the brain in response to a combination of attractive and repulsive cues.
90260	negative regulation of retinal ganglion cell axon guidance	P	Any process that decreases the frequency, rate, or extent of retinal ganglion cell axon guidance, the process in which the migration of an axon growth cone of a retinal ganglion cell (RGC) is directed to its target in the brain in response to a combination of attractive and repulsive cues.
90261	positive regulation of inclusion body assembly	P	Any process that increases the rate, frequency, or extent of inclusion body assembly. Inclusion body assembly is the aggregation, arrangement and bonding together of a set of components to form an inclusion body.
90262	regulation of transcription-coupled nucleotide-excision repair	P	Any process that modulates the frequency, rate, or extent of the nucleotide-excision repair process that carries out preferential repair of DNA lesions on the actively transcribed strand of the DNA duplex. In addition, the transcription-coupled nucleotide-excision repair pathway is required for the recognition and repair of a small subset of lesions that are not recognized by the global genome nucleotide excision repair pathway.
90263	positive regulation of canonical Wnt signaling pathway	P	Any process that increases the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin, the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes.
90264	regulation of immune complex clearance by monocytes and macrophages	P	Any process that modulates the rate, frequency, or extent of the process of immune complex clearance by monocytes or macrophages.
90265	positive regulation of immune complex clearance by monocytes and macrophages	P	Any process that increases the rate, frequency, or extent of the process of immune complex clearance by monocytes or macrophages.
90266	regulation of mitotic cell cycle spindle assembly checkpoint	P	Any process that modulates the rate, frequency, or extent of the mitotic cell cycle spindle assembly checkpoint, a cell cycle checkpoint that delays the metaphase/anaphase transition of a mitotic nuclear division until the spindle is correctly assembled and chromosomes are attached to the spindle.
90267	positive regulation of mitotic cell cycle spindle assembly checkpoint	P	Any process that increases the rate, frequency, or extent of the mitotic cell cycle spindle assembly checkpoint, a cell cycle checkpoint that delays the metaphase/anaphase transition of a mitotic nuclear division until the spindle is correctly assembled and chromosomes are attached to the spindle.
90268	activation of mitotic cell cycle spindle assembly checkpoint	P	Any process that starts the inactive process of a mitotic cell cycle spindle assembly checkpoint.
90269	fibroblast growth factor production	P	The appearance of a fibroblast growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
90270	regulation of fibroblast growth factor production	P	Any process that modulates the rate, frequency or extent of the appearance of a fibroblast growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
90271	positive regulation of fibroblast growth factor production	P	Any process that increases the rate, frequency or extent of the appearance of a fibroblast growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
90272	negative regulation of fibroblast growth factor production	P	Any process that decreases the rate, frequency or extent of the appearance of a fibroblast growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
90273	regulation of somatostatin secretion	P	Any process that modulates the rate, frequency, extent of the regulated release of somatostatin from secretory granules in the D cells of the pancreas.
90274	positive regulation of somatostatin secretion	P	Any process that increases the rate, frequency, extent of the regulated release of somatostatin from secretory granules in the D cells of the pancreas.
90275	negative regulation of somatostatin secretion	P	Any process that decreases the rate, frequency, extent of the regulated release of somatostatin from secretory granules in the D cells of the pancreas.
90276	regulation of peptide hormone secretion	P	Any process that modulates the rate, frequency, or extent of the regulated release of a peptide hormone from secretory granules.
90277	positive regulation of peptide hormone secretion	P	Any process that increases the rate, frequency, or extent of the regulated release of a peptide hormone from secretory granules.
90278	negative regulation of peptide hormone secretion	P	Any process that decreases the rate, frequency, or extent of the regulated release of a peptide hormone from secretory granules.
90279	regulation of calcium ion import	P	Any process that modulates the rate, frequency, or extent of the directed movement of calcium ions into a cell or organelle.
90280	positive regulation of calcium ion import	P	Any process that increases the rate, frequency, or extent of the directed movement of calcium ions into a cell or organelle.
90281	negative regulation of calcium ion import	P	Any process that decreases the rate, frequency, or extent of the directed movement of calcium ions into a cell or organelle.
90282	positive regulation of transcription involved in G2/M transition of mitotic cell cycle	P	Any process that activates or increases the frequency, rate or extent of transcription of target genes that are transcribed as part of the G2/M transition of the mitotic cell cycle.
90283	regulation of protein glycosylation in Golgi	P	Any process that modulates the rate, frequency, or extent of the addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid in any compartment of the Golgi apparatus.
90284	positive regulation of protein glycosylation in Golgi	P	Any process that increases the rate, frequency, or extent of the addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid in any compartment of the Golgi apparatus.
90285	negative regulation of protein glycosylation in Golgi	P	Any process that decreases the rate, frequency, or extent of the addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid in any compartment of the Golgi apparatus.
90286	cytoskeletal anchoring at nuclear membrane	P	The process in which cytoskeletal filaments are directly or indirectly linked to the nuclear membrane.
90287	regulation of cellular response to growth factor stimulus	P	Any process that modulates the rate, frequency, or extent of a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a growth factor stimulus.
90288	negative regulation of cellular response to growth factor stimulus	P	Any process that decreases the rate, frequency, or extent of a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a growth factor stimulus.
90289	regulation of osteoclast proliferation	P	Any process that modulates the rate, frequency, or extent of the multiplication or reproduction of osteoclasts, resulting in the expansion of an osteoclast cell population.
90290	positive regulation of osteoclast proliferation	P	Any process that increases the rate, frequency, or extent of the multiplication or reproduction of osteoclasts, resulting in the expansion of an osteoclast cell population.
90291	negative regulation of osteoclast proliferation	P	Any process that decreases the rate, frequency, or extent of the multiplication or reproduction of osteoclasts, resulting in the expansion of an osteoclast cell population.
90292	nuclear matrix anchoring at nuclear membrane	P	The process in which the nuclear matrix, the dense fibrillar network lying on the inner side of the nuclear membrane, is directly or indirectly linked to the nuclear membrane.
90293	nitrogen catabolite regulation of transcription	P	A transcription regulation process in which the presence of one nitrogen source leads to the modulation of the frequency, rate, or extent of transcription of specific genes involved in the metabolism of other nitrogen sources.
90294	nitrogen catabolite activation of transcription	P	A transcription regulation process in which the presence of one nitrogen source leads to an increase in the frequency, rate, or extent of transcription of specific genes involved in the metabolism of other nitrogen sources.
90295	nitrogen catabolite repression of transcription	P	A transcription regulation process in which the presence of one nitrogen source leads to a decrease in the frequency, rate, or extent of transcription of specific genes involved in the metabolism of other nitrogen sources.
90296	regulation of mitochondrial DNA replication	P	Any process that modulates the rate, frequency or extent of the process in which new strands of DNA are synthesized in the mitochondrion.
90297	positive regulation of mitochondrial DNA replication	P	Any process that increases the rate, frequency or extent of the process in which new strands of DNA are synthesized in the mitochondrion.
90298	negative regulation of mitochondrial DNA replication	P	Any process that decreases the rate, frequency or extent of the process in which new strands of DNA are synthesized in the mitochondrion.
90299	regulation of neural crest formation	P	Any process that modulates the rate, frequency, or extent of neural crest formation. Neural crest formation is the formation of the specialized region of ectoderm between the neural ectoderm (neural plate) and non-neural ectoderm. The neural crest gives rise to the neural crest cells that migrate away from this region as neural tube formation proceeds.
90300	positive regulation of neural crest formation	P	Any process that increases the rate, frequency, or extent of neural crest formation. Neural crest formation is the formation of the specialized region of ectoderm between the neural ectoderm (neural plate) and non-neural ectoderm. The neural crest gives rise to the neural crest cells that migrate away from this region as neural tube formation procedes.
90301	negative regulation of neural crest formation	P	Any process that decreases the rate, frequency, or extent of neural crest formation. Neural crest formation is the formation of the specialized region of ectoderm between the neural ectoderm (neural plate) and non-neural ectoderm. The neural crest gives rise to the neural crest cells that migrate away from this region as neural tube formation procedes.
90303	positive regulation of wound healing	P	Any process that increases the rate, frequency, or extent of the series of events that restore integrity to a damaged tissue, following an injury.
90304	nucleic acid metabolic process	P	Any cellular metabolic process involving nucleic acids.
90305	nucleic acid phosphodiester bond hydrolysis	P	The nucleic acid metabolic process in which the phosphodiester bonds between nucleotides are cleaved by hydrolysis.
90306	spindle assembly involved in meiosis	P	The aggregation, arrangement and bonding together of a set of components to form the spindle that contributes to the process of meiosis.
90307	mitotic spindle assembly	P	The aggregation, arrangement and bonding together of a set of components to form the spindle that contributes to the process of mitosis.
90308	regulation of methylation-dependent chromatin silencing	P	Any process that modulates the rate, frequency, or extent of the repression of transcription by methylation of DNA, leading to the formation of heterochromatin.
90309	positive regulation of methylation-dependent chromatin silencing	P	Any process that increases the rate, frequency, or extent of the repression of transcription by methylation of DNA, leading to the formation of heterochromatin.
90310	negative regulation of methylation-dependent chromatin silencing	P	Any process that decreases the rate, frequency, or extent of the repression of transcription by methylation of DNA, leading to the formation of heterochromatin.
90311	regulation of protein deacetylation	P	Any process that modulates the rate, frequency, or extent of protein deacetylation, the removal of an acetyl group from a protein amino acid. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid.
90312	positive regulation of protein deacetylation	P	Any process that increases the rate, frequency, or extent of protein deacetylation, the removal of an acetyl group from a protein amino acid. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid.
90313	regulation of protein targeting to membrane	P	Any process that modulates the frequency, rate or extent of the process of directing proteins towards a membrane, usually using signals contained within the protein.
90314	positive regulation of protein targeting to membrane	P	Any process that increases the frequency, rate or extent of the process of directing proteins towards a membrane, usually using signals contained within the protein.
90315	negative regulation of protein targeting to membrane	P	Any process that decreases the frequency, rate or extent of the process of directing proteins towards a membrane, usually using signals contained within the protein.
90316	positive regulation of intracellular protein transport	P	Any process that activates or increases the frequency, rate or extent of the directed movement of proteins within cells.
90317	negative regulation of intracellular protein transport	P	Any process that decreases the frequency, rate or extent of the directed movement of proteins within cells.
90318	regulation of chylomicron remodeling	P	Any process that modulates the rate, frequency, or extent of chylomicron remodeling. Chylomicron remodeling is the acquisition, loss or modification of a protein or lipid within a chylomicron, including the hydrolysis of triglyceride by lipoprotein lipase and the subsequent loss of free fatty acid.
90319	positive regulation of chylomicron remodeling	P	Any process that increases the rate, frequency, or extent of chylomicron remodeling. Chylomicron remodeling is the acquisition, loss or modification of a protein or lipid within a chylomicron, including the hydrolysis of triglyceride by lipoprotein lipase and the subsequent loss of free fatty acid.
90320	regulation of chylomicron remnant clearance	P	Any process that modulates the rate, frequency or extent of chylomicron remnant clearance. Chylomicron clearance is the process in which a chylomicron remnant is removed from the blood via receptor-mediated endocytosis into liver cells and its constituent parts degraded.
90321	positive regulation of chylomicron remnant clearance	P	Any process that increases the rate, frequency or extent of chylomicron remnant clearance. Chylomicron clearance is the process in which a chylomicron remnant is removed from the blood via receptor-mediated endocytosis into liver cells and its constituent parts degraded.
90322	regulation of superoxide metabolic process	P	Any process that modulates the rate, frequency, or extent of superoxide metabolism, the chemical reactions and pathways involving superoxide, the superoxide anion O2- (superoxide free radical), or any compound containing this species.
90323	prostaglandin secretion involved in immune response	P	The regulated release of a prostaglandin that contributes to the immune response. Prostaglandins are a group of biologically active metabolites which contain a cyclopentane ring.
90324	negative regulation of oxidative phosphorylation	P	Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the phosphorylation of ADP to ATP that accompanies the oxidation of a metabolite through the operation of the respiratory chain. Oxidation of compounds establishes a proton gradient across the membrane, providing the energy for ATP synthesis.
90325	regulation of locomotion involved in locomotory behavior	P	Any process that modulates the frequency, rate, or extent of the self-propelled movement of a cell or organism from one location to another in a behavioral context; the aspect of locomotory behavior having to do with movement.
90326	positive regulation of locomotion involved in locomotory behavior	P	Any process that increases the frequency, rate, or extent of the self-propelled movement of a cell or organism from one location to another in a behavioral context; the aspect of locomotory behavior having to do with movement.
90327	negative regulation of locomotion involved in locomotory behavior	P	Any process that decreases the frequency, rate, or extent of the self-propelled movement of a cell or organism from one location to another in a behavioral context; the aspect of locomotory behavior having to do with movement.
90328	regulation of olfactory learning	P	Any process that modulates the rate, frequency, or extent of olfactory learning. Olfactory learning is any process in an organism in which a relatively long-lasting adaptive behavioral change occurs in response to (repeated) exposure to an olfactory cue.
90329	regulation of DNA-dependent DNA replication	P	Any process that modulates the rate, frequency, or extent of DNA-dependent DNA replication, the process in which new strands of DNA are synthesized, using parental DNA as a template for the DNA-dependent DNA polymerases that synthesize the new strands.
90330	regulation of platelet aggregation	P	Any process that modulates the rate, frequency or extent of platelet aggregation. Platelet aggregation is the adhesion of one platelet to one or more other platelets via adhesion molecules.
90331	negative regulation of platelet aggregation	P	Any process that decreases the rate, frequency or extent of platelet aggregation. Platelet aggregation is the adhesion of one platelet to one or more other platelets via adhesion molecules.
90332	stomatal closure	P	The process of closing of stomata, pores in the epidermis of leaves and stems bordered by two guard cells and serving in gas exchange.
90333	regulation of stomatal closure	P	Any process that modulates the rate, frequency, or extent of stomatal closure. Stomatal closure is the process of closing of stomata, pores in the epidermis of leaves and stems bordered by two guard cells and serving in gas exchange.
90334	regulation of cell wall (1->3)-beta-D-glucan biosynthetic process	P	Any process that modulates the rate, frequency, or extent of the chemical reactions and pathways resulting in the formation of (1->3)-beta-D-glucans, compounds composed of glucose residues linked by (1->3)-beta-D-glucosidic bonds, found in the walls of cells.
90335	regulation of brown fat cell differentiation	P	Any process that modulates the rate, frequency, or extent of brown fat cell differentiation. Brown fat cell differentiation is the process in which a relatively unspecialized cell acquires specialized features of a brown adipocyte, an animal connective tissue cell involved in adaptive thermogenesis. Brown adipocytes contain multiple small droplets of triglycerides and a high number of mitochondria.
90336	positive regulation of brown fat cell differentiation	P	Any process that increases the rate, frequency, or extent of brown fat cell differentiation. Brown fat cell differentiation is the process in which a relatively unspecialized cell acquires specialized features of a brown adipocyte, an animal connective tissue cell involved in adaptive thermogenesis. Brown adipocytes contain multiple small droplets of triglycerides and a high number of mitochondria.
90337	regulation of formin-nucleated actin cable assembly	P	Any process that modulates the rate, frequency, or extent of formin-nucleated actin cable assembly. Formin-nucleated actin cable assembly is the aggregation, arrangement and bonding together of a set of components to form a formin-nucleated actin cable. A formin-nucleated actin cable is an actin filament bundle that consists of short filaments organized into bundles of uniform polarity, and is nucleated by formins.
90338	positive regulation of formin-nucleated actin cable assembly	P	Any process that increases the rate, frequency, or extent of formin-nucleated actin cable assembly. Formin-nucleated actin cable assembly is the aggregation, arrangement and bonding together of a set of components to form a formin-nucleated actin cable. A formin-nucleated actin cable is an actin filament bundle that consists of short filaments organized into bundles of uniform polarity, and is nucleated by formins.
90339	negative regulation of formin-nucleated actin cable assembly	P	Any process that decreases the rate, frequency, or extent of formin-nucleated actin cable assembly. Formin-nucleated actin cable assembly is the aggregation, arrangement and bonding together of a set of components to form a formin-nucleated actin cable. A formin-nucleated actin cable is an actin filament bundle that consists of short filaments organized into bundles of uniform polarity, and is nucleated by formins.
90340	positive regulation of secretion of lysosomal enzymes	P	Any process that increases the rate, frequency or extent of secretion of lysosomal enzymes, the controlled release of lysosomal enzymes by a cell.
90341	negative regulation of secretion of lysosomal enzymes	P	Any process that decreases the rate, frequency or extent of secretion of lysosomal enzymes, the controlled release of lysosomal enzymes by a cell.
90342	regulation of cell aging	P	Any process that modulates the rate, frequency, or extent of cell aging. Cell aging is the progression of the cell from its inception to the end of its lifespan.
90343	positive regulation of cell aging	P	Any process that increases the rate, frequency, or extent of cell aging. Cell aging is the progression of the cell from its inception to the end of its lifespan.
90344	negative regulation of cell aging	P	Any process that decreases the rate, frequency, or extent of cell aging. Cell aging is the progression of the cell from its inception to the end of its lifespan.
90345	cellular organohalogen metabolic process	P	The chemical reactions and pathways involving organohalogen compounds, as carried out by individual cells.
90346	cellular organofluorine metabolic process	P	The chemical reactions and pathways involving organofluorine compounds, as carried out by individual cells.
90347	regulation of cellular organohalogen metabolic process	P	Any process that modulates the rate, frequency or extent of the chemical reactions and pathways involving organohalogen compounds, as carried out by individual cells.
90348	regulation of cellular organofluorine metabolic process	P	Any process that modulates the rate, frequency or extent of the chemical reactions and pathways involving organofluorine compounds, as carried out by individual cells.
90349	negative regulation of cellular organohalogen metabolic process	P	Any process that decreases the rate, frequency or extent of the chemical reactions and pathways involving organohalogen compounds, as carried out by individual cells.
90350	negative regulation of cellular organofluorine metabolic process	P	Any process that decreases the rate, frequency or extent of the chemical reactions and pathways involving organofluorine compounds, as carried out by individual cells.
90351	seedling development	P	The process whose specific outcome is the progression of the seedling over time, beginning with seed germination and ending when the first adult leaves emerge.
90352	regulation of nitrate assimilation	P	Any process that modulates the rate, frequency, or extent of the uptake, from the environment, of nitrates, inorganic or organic salts and esters of nitric acid and the subsequent reduction of nitrate ion to other, less highly oxidized, inorganic nitrogenous substances.
90353	polygalacturonase inhibitor activity	F	Stops, prevents or reduces the activity of a polygalacturonase. Polygalacturonases catalyze the random hydrolysis of 1,4-alpha-D-galactosiduronic linkages in pectate and other galacturonans.
90354	regulation of auxin metabolic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving auxins, plant hormones that regulate aspects of plant growth.
90355	positive regulation of auxin metabolic process	P	Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving auxins, plant hormones that regulate aspects of plant growth.
90356	negative regulation of auxin metabolic process	P	Any process that decreases the frequency, rate or extent of the chemical reactions and pathways involving auxins, plant hormones that regulate aspects of plant growth.
90357	regulation of tryptophan metabolic process	P	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving tryptophan, the chiral amino acid 2-amino-3-(1H-indol-3-yl)propanoic acid.
90358	positive regulation of tryptophan metabolic process	P	Any process that increases the frequency, rate or extent of the chemical reactions and pathways involving tryptophan, the chiral amino acid 2-amino-3-(1H-indol-3-yl)propanoic acid.
90359	negative regulation of abscisic acid biosynthetic process	P	Any process that decreases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of abscisic acid.
90360	platelet-derived growth factor production	P	The appearance of any platelet-derived growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
90361	regulation of platelet-derived growth factor production	P	Any process that modulates the rate, frequency, or extent of the appearance of any platelet-derived growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
90362	positive regulation of platelet-derived growth factor production	P	Any process that increases the rate, frequency, or extent of the appearance of any platelet-derived growth factor due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
90363	regulation of proteasome core complex assembly	P	Any process that modulates the rate, frequency, or extent of the aggregation, arrangement and bonding together of a mature, active 20S proteasome core particle complex that does not contain any regulatory particles.
90364	regulation of proteasome assembly	P	Any process that modulates the rate, frequency, or extent of the aggregation, arrangement and bonding together of a mature, active proteasome complex.
90365	regulation of mRNA modification	P	Any process that modulates the rate, frequency, or extent of the covalent alteration of one or more nucleotides within an mRNA molecule to produce an mRNA molecule with a sequence that differs from that coded genetically.
90366	positive regulation of mRNA modification	P	Any process that increases the rate, frequency, or extent of the covalent alteration of one or more nucleotides within an mRNA molecule to produce an mRNA molecule with a sequence that differs from that coded genetically.
90367	negative regulation of mRNA modification	P	Any process that decreases the rate, frequency, or extent of the covalent alteration of one or more nucleotides within an mRNA molecule to produce an mRNA molecule with a sequence that differs from that coded genetically.
90368	regulation of ornithine metabolic process	P	Any process that modulates the rate, frequency, or extent of the chemical reactions and pathways involving ornithine, an amino acid only rarely found in proteins, but which is important in living organisms as an intermediate in the reactions of the urea cycle and in arginine biosynthesis.
90369	ornithine carbamoyltransferase inhibitor activity	F	Stops, prevents, or reduces ornithine carbamoyltransferase activity, the catalysis of the reaction: carbamoyl phosphate + L-ornithine = phosphate + L-citrulline.
90370	negative regulation of cholesterol efflux	P	Any process that decreases the frequency, rate or extent of cholesterol efflux. Cholesterol efflux is the directed movement of cholesterol, cholest-5-en-3-beta-ol, out of a cell or organelle.
90371	regulation of glycerol transport	P	Any process that modulates the rate, frequency, or extent of the directed movement of glycerol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
90372	positive regulation of glycerol transport	P	Any process that increases the rate, frequency, or extent of the directed movement of glycerol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
90373	negative regulation of glycerol transport	P	Any process that decreases the rate, frequency, or extent of the directed movement of glycerol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
90374	oligopeptide export from mitochondrion	P	The directed movement of oligopeptides out of mitochondria into the cytosol by means of some agent such as a transporter or pore. Oligopeptides are molecules that contain a small number (2 to 20) of amino-acid residues connected by peptide linkages.
90375	negative regulation of transcription from RNA polymerase II promoter in response to iron ion starvation	P	Any process that decreases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of deprivation of iron ions.
90376	seed trichome differentiation	P	The process in which a relatively unspecialized epidermal cell acquires the specialized features of a seed trichome. A seed trichome is a trichome that develops from seed coat epidermis and is often long with putative dispersal function.
90377	seed trichome initiation	P	The process in which the developmental fate of an epidermal cell becomes restricted such that it will develop into a seed trichome, causing a change in the orientation of cell division in the ovule epidermis at or just before anthesis.
90378	seed trichome elongation	P	The process in which a seed trichome irreversibly increases in size in one [spatial] dimension or along one axis, resulting in the morphogenesis of the cell.
90379	secondary cell wall biogenesis involved in seed trichome differentiation	P	A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of inextensible cellulose- and pectin-containing cell walls that are formed between the plasma membrane and primary cell wall of seed trichomes after cell expansion is complete.
90380	seed trichome maturation	P	A developmental process, independent of morphogenetic (shape) change, that is required for a seed trichome to attain its fully functional state.
90381	regulation of heart induction	P	Any process that modulates the rate, frequency, or extent of heart induction. Heart induction is the close range interaction between mesoderm and endoderm or ectoderm that causes cells to change their fates and specify the development of the heart.
90382	phagosome maturation	P	A process that is carried out at the cellular level which results in the arrangement of constituent parts of a phagosome within a cell. Phagosome maturation begins with endocytosis and formation of the early phagosome and ends with the formation of the hybrid organelle, the phagolysosome.
90383	phagosome acidification	P	Any process that reduces the pH of the phagosome, measured by the concentration of the hydrogen ion.
90384	phagosome-lysosome docking	P	The initial attachment of a phagosome membrane to a lysosome membrane. Docking requires only that the proteins come close enough to interact and adhere.
90385	phagosome-lysosome fusion	P	The creation of a phagolysosome from a phagosome and a lysosome.
90386	phagosome maturation involved in apoptotic cell clearance	P	A process that is carried out at the cellular level which results in the arrangement of constituent parts of a phagosome within a cell and contributes to apoptotic cell clearance. Phagosome maturation begins with endocytosis and formation of the early phagosome and ends with the formation of the hybrid organelle, the phagolysosome.
90387	phagolysosome assembly involved in apoptotic cell clearance	P	The process in which a phagosome, a vesicle formed by phagocytosis, fuses with a lysosome as a part of apoptotic cell clearance.
90388	phagosome-lysosome docking involved in apoptotic cell clearance	P	The initial attachment of a phagosome membrane to a lysosome membrane that occurs as a part of apoptotic cell clearance. Docking requires only that the proteins come close enough to interact and adhere.
90389	phagosome-lysosome fusion involved in apoptotic cell clearance	P	The creation of a phagolysosome from a phagosome and a lysosome as a part of apoptotic cell clearance.
90390	phagosome acidification involved in apoptotic cell clearance	P	Any process that reduces the pH of the phagosome, measured by the concentration of the hydrogen ion, and occurs as a part of apoptotic cell clearance.
90391	granum assembly	P	A process that is carried out at the cellular level which results in the assembly of a granum. A granum is a distinct stack of lamellae seen within chloroplasts.
90392	sepal giant cell differentiation	P	The process in which a relatively unspecialized cell acquires specialized features of a sepal giant cell. A sepal giant cell is a pavement cell that is part of the sepal epidermis and stretches one fifth the length of the sepal with a chromosome content of 16C.
90393	sepal giant cell development	P	The process aimed at the progression of a sepal giant cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.
90394	negative regulation of excitatory postsynaptic potential	P	Any process that prevents the establishment or decreases the extent of the excitatory postsynaptic potential (EPSP) which is a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell. The flow of ions that causes an EPSP is an excitatory postsynaptic current (EPSC) and makes it easier for the neuron to fire an action potential.
90395	plant cell papilla	C	A cell projection that is a short, rounded projection from a plant epidermal cell.
90396	leaf papilla	C	A plant cell papilla that is part of a leaf papilla cell.
90397	stigma papilla	C	A plant cell papilla that is part of a stigma papilla cell.
90398	cellular senescence	P	A cell aging process stimulated in response to cellular stress, whereby normal cells lose the ability to divide through irreversible cell cycle arrest.
90399	replicative senescence	P	A cell aging process associated with the dismantling of a cell as a response to telomere shortening and/or cellular aging.
90400	stress-induced premature senescence	P	A cellular senescence process associated with the dismantling of a cell as a response to environmental factors such as hydrogen peroxide or X-rays.
90401	viral-induced premature senescence	P	A cellular senescence process associated with the dismantling of a cell as a response to viral infection.
90402	oncogene-induced cell senescence	P	A cellular senescence process associated with the dismantling of a cell as a response to oncogenic stress, such as the activation of the Ras oncogenic family.
90403	oxidative stress-induced premature senescence	P	A cellular senescence process associated with the dismantling of a cell as a response to oxidative stress, e.g. high levels of reactive oxygen species, such as superoxide anions, hydrogen peroxide, and hydroxyl radicals.
90404	pollen tube tip	C	The region at growing end of the pollen tube cell, where polarized growth occurs.
90405	unicellular trichome branch	C	A cell projection part that is a branch of a unicellular trichome.
90406	pollen tube	C	A tubular cell projection that is part of a pollen tube cell and extends from a pollen grain.
90407	organophosphate biosynthetic process	P	The chemical reactions and pathways resulting in the biosynthesis of deoxyribose phosphate, the phosphorylated sugar 2-deoxy-erythro-pentose.
90408	phloem nitrate loading	P	The process of loading nitrate into the sieve tube or companion cell of the phloem for long distance transport from source to sink.
90409	malonyl-CoA synthetase activity	F	Catalysis of the reaction: malonate + ATP + coenzyme A = malonyl-CoA + AMP + diphosphate.
90410	malonate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of malonate, the propanedioate ion.
90411	brassinosteroid binding	F	Interacting selectively and non-covalently with a brassinosteroid.
90414	molybdate ion export from vacuole	P	The directed movement of molybdate ions out of the vacuole.
90415	7-hydroxymethyl chlorophyll a reductase activity	F	Catalysis of the reaction: 7-hydroxymethyl chlorophyll a + 2 reduced ferredoxin + 2 H+ chlorophyll a + 2 oxidized ferredoxin + H2O.
90416	nicotinate transporter activity	F	Enables the directed movement of nicotinate into, out of or within a cell, or between cells.
90417	N-methylnicotinate transporter activity	F	Enables the directed movement of N-methylnicotinate into, out of or within a cell, or between cells.
90419	negative regulation of transcription involved in G2/M transition of mitotic cell cycle	P	Any process that inhibits or decreases the frequency, rate or extent of transcription of target genes that are transcribed as part of the G2/M transition of the mitotic cell cycle.
90420	naphthalene-containing compound metabolic process	P	The chemical reactions and pathways involving naphthalene-containing compounds.
90421	embryonic meristem initiation	P	Initiation of a region of tissue in a plant embryo that is composed of one or more undifferentiated cells capable of undergoing mitosis and differentiation.
90422	thiamine pyrophosphate transporter activity	F	Enables the directed movement of thiamine pyrophosphate into, out of or within a cell, or between cells.
90423	phytochelatin-metal complex formation	P	A phytochelatin metabolic process in which a metal is incorporated with phytochelatin to form a complex.
90424	phytochelatin-metal-sulfur complex formation	P	A phytochelatin metabolic process in which a metal and exogenous sulfur are incorporated with phytochelatin to form a complex.
90425	acinar cell differentiation	P	The epithelial cell differentiation process in which a relatively unspecialized cell acquires specialized features of an acinar cell, a secretory cell that is grouped together with other cells of the same type to form grape-shaped clusters known as acini.
90426	actin filament bundle convergence	P	A process of actin filament bundle distribution that results in the compaction of actin filaments.
90427	activation of meiosis	P	Any process that starts the inactive process of meiosis.
90428	perianth development	P	The process whose specific outcome is the progression of the perianth over time, from its formation to the mature structure. The perianth is a collective phyllome structure composed of two or more petals, sepals, or tepals.
90429	detection of endogenous biotic stimulus	P	The series of events in which an endogenous biotic stimulus is received by a cell and converted into a molecular signal.
90430	caffeoyl-CoA: alcohol caffeoyl transferase activity	F	Catalysis of the reaction: caffeoyl-CoA + a saturated primary alcohol = an alkyl caffeate + CoA.
90431	alkyl caffeate ester biosynthetic process	P	The chemical reactions and pathways resulting in the formation of ester derivatives of alkyl caffeate.
90432	myristoyl-CoA ligase activity	F	Catalysis of the reaction: ATP + myristic acid + CoA = AMP + diphosphate + myristoyl-CoA.
90433	palmitoyl-CoA ligase activity	F	Catalysis of the reaction: ATP + palmitic acid + CoA = AMP + diphosphate + palmitoyl-CoA.
90434	oleoyl-CoA ligase activity	F	Catalysis of the reaction: ATP + oleic acid + CoA = AMP + diphosphate + oleoyl-CoA.
90435	protein localization to nuclear envelope	P	A process in which a protein is transported to, or maintained at, a location within a nuclear envelope.
90436	leaf pavement cell development	P	The process whose specific outcome is the progression of an leaf pavement cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a leaf pavement cell fate.
90437	socket cell differentiation	P	The process in which a relatively unspecialized cell acquires specialized features of a socket cell, a shoot epidermal cell that surrounds a trichome and provides its support.
90438	camelliol C synthase activity	F	Catalyzes the reaction: (3S)-2,3-epoxy-2,3-dihydrosqualene = camelliol C.
90439	tetraketide alpha-pyrone synthase activity	F	Catalyzes the reaction: a hydroxyacyl-CoA + 3 malonyl-CoA + 2 H+ = a hydroxylated tetraketide alpha-pyrone + 3 CO2 + 4 coenzyme A.
90440	abscisic acid transporter activity	F	Enables the directed movement of abscisic acid into, out of or within a cell, or between cells.
90441	trehalose biosynthesis in response to heat stress	P	The chemical reactions and pathways resulting in the formation of trehalose that occur as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.
90442	trehalose catabolism in response to heat stress	P	The chemical reactions and pathways resulting in the degradation of trehalose that occur as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.
90443	FAR/SIN/STRIPAK complex	C	A conserved protein phosphatase type 2A complex which contains a protein phosphatase type 2A, a protein phosphatase regulatory subunit, a striatin, an FHA domain protein and other subunits (at least six proteins). In fission yeast this complex negatively regulate the septation initiation network at the spindle pole body.
90444	regulation of nematode larval development, heterochronic	P	Any process that modulates the consistent predetermined time point at which a nematode larva progresses from an initial condition to a later condition and the rate at which this time point is reached.
90445	positive regulation of nematode larval development, heterochronic	P	Any process that modulates the consistent predetermined time point at which a nematode larva progresses from an initial condition to a later condition and increases the rate at which this time point is reached.
90446	negative regulation of nematode larval development, heterochronic	P	Any process that modulates the consistent predetermined time point at which a nematode larva progresses from an initial condition to a later condition and decreases the rate at which this time point is reached.
90447	glycerol-3-phosphate 2-O-acyltransferase activity	F	Catalysis of the reaction: an acyl-CoA + sn-glycerol 3-phosphate = CoA + a 2-acyl-sn-glycerol 3-phosphate.
90448	glucosinolate:proton symporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: glucosinolate(out) + H+(out) = glucosinolate(in) + H+(in).
90449	phloem glucosinolate loading	P	The process of loading glucosinolates into the sieve tube or companion cell of the phloem for long distance transport from source to sink.
90451	cotyledon boundary formation	P	The process in which boundaries between a cotyledon and the surrounding tissue are established and maintained.
90452	lithium ion import	P	The directed movement of lithium ions into a cell or organelle.
90453	aspartate transmembrane import into vacuole	P	The directed movement of aspartate into the vacuole across the vacuolar membrane.
90454	glutamate transmembrane import into vacuole	P	The directed movement of glutamate into the vacuole across the vacuolar membrane.
90455	ornithine transmembrane import into vacuole	P	The directed movement of ornithine into the vacuole across the vacuolar membrane.
90456	lysine transmembrane import into vacuole	P	The directed movement of lysine into the vacuole across the vacuolar membrane.
90457	histidine transmembrane import into vacuole	P	The directed movement of histidine into the vacuole across the vacuolar membrane.
90458	arginine transmembrane import into vacuole	P	The directed movement of arginine into the vacuole across the vacuolar membrane.
90459	aspartate homeostasis	P	Any process involved in the maintenance of an internal steady state of aspartate within an organism or cell.
90460	threonine homeostasis	P	Any process involved in the maintenance of an internal steady state of threonine within an organism or cell.
90461	glutamate homeostasis	P	Any process involved in the maintenance of an internal steady state of glutamate within an organism or cell.
90462	ornithine homeostasis	P	Any process involved in the maintenance of an internal steady state of ornithine within an organism or cell.
90463	lysine homeostasis	P	Any process involved in the maintenance of an internal steady state of lysine within an organism or cell.
90464	histidine homeostasis	P	Any process involved in the maintenance of an internal steady state of histidine within an organism or cell.
90465	arginine homeostasis	P	Any process involved in the maintenance of an internal steady state of arginine within an organism or cell.
90466	histidine import	P	The directed movement of histidine into a cell or organelle.
90467	arginine import	P	The directed movement of arginine into a cell or organelle.
90468	valine import	P	The directed movement of valine into a cell or organelle.
90469	asparagine import	P	The directed movement of asparagine into a cell or organelle.
90470	shoot organ boundary specification	P	The process in which the basal boundary between the stem and both vegetative and reproductive organs are established and maintained.
90471	9,15,9'-tri-cis-zeta-carotene isomerase activity	F	Catalysis of the reaction: 9,15,9'-tricis-zeta-carotene = 9,9'-dicis-zeta-carotene.
90472	dibasic protein processing	P	Any protein processing achieved by the cleavage of a peptide bond after two basic amino acids within a protein.
90473	lys-arg specific dibasic protein processing	P	Any protein processing achieved by the cleavage of a peptide bond after a lysine-arginine amino acid residue combination within a protein.
90474	arg-arg specific dibasic protein processing	P	Any protein processing achieved by the cleavage of a peptide bond after two consecutive arginine amino acid residues within a protein.
90475	lys-lys specific dibasic protein processing	P	Any protein processing achieved by the cleavage of a peptide bond after two consecutive lysine amino acid residues within a protein.
90476	isoleucine import	P	The directed movement of isoleucine into a cell or organelle.
90477	L-isoleucine import	P	The directed movement of L-isoleucine, the L-enantiomer of isoleucine, into a cell or organelle.
90478	serine import	P	The directed movement of serine into a cell or organelle.
90479	L-serine import	P	The directed movement of L-serine, the L-enantiomer of serine, into a cell or organelle.
90480	purine nucleotide-sugar transmembrane transport	P	The directed movement of a purine nucleotide-sugar across a membrane. Purine nucleotide-sugars are purine nucleotides in glycosidic linkage with a monosaccharide or monosaccharide derivative.
90481	pyrimidine nucleotide-sugar transmembrane transport	P	The directed movement of pyrimidine nucleotide-sugars across a membrane. Pyrimidine nucleotide-sugars are pyrimidine nucleotides in glycosidic linkage with a monosaccharide or monosaccharide derivative.
90482	vitamin transmembrane transporter activity	F	Enables the transfer of a vitamin from one side of a membrane to the other.
90483	phosphatidylglycerol-phosphatidylethanolamine phosphatidyltransferase activity	F	Catalysis of the reaction: phosphatidylglycerol + phosphatidylethanolamine = cardiolipin + ethanolamine.
90484	drug transporter activity	F	Enables the directed movement of a drug into, out of or within a cell, or between cells. A drug is any naturally occurring or synthetic substance, other than a nutrient, that, when administered or applied to an organism, affects the structure or functioning of the organism; in particular, any such substance used in the diagnosis, prevention, or treatment of disease.
90485	chromosome number maintenance	P	The maintenance of the standard number of chromosomes in a cell.
90486	small RNA 2'-O-methyltransferase	F	Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to the oxygen atom of a nucleoside residue in a small RNA molecule. Reaction: S-adenosyl-L-methionine + small RNA <=> S-adenosyl-L-homocysteine + small RNA containing a 3'-terminal 2'-O-methylnucleotide.
90487	secondary metabolite catabolic process	P	The chemical reactions and pathways resulting in the breakdown of secondary metabolites, the compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon.
90488	polo box domain specific binding	F	Interacting selectively and non-covalently with a polo box domain of a protein. The polo box domain is involved in binding substrates of polo kinases.
90489	L-tryptophan,NADPH:oxygen oxidoreductase (N-hydroxylating, decarboxylating)	F	Catalyzes the multi-step reaction: L-Tryptophan + 2 Oxygen + 2 NADPH + 2 H+ = Indole-3-acetaldehyde oxime + 3 H2O + 2 NADP+ + CO2. The individual reactions are: (1a) L-tryptophan + O2 + NADPH + H+ = N-hydroxy-L-tryptophan + NADP+ + H2O,(1b) N-hydroxy-L-tryptophan + O2 + NADPH + H+ = N,N-dihydroxy-L-tryptophan + NADP+ + H2O, and (1c) N,N-dihydroxy-L-tryptophan = (E)-indol-3-ylacetaldoxime + CO2 + H2O.
90490	L-tryptophan,NADPH:oxygen oxidoreductase (N-hydroxylating)	F	Catalyzes the reaction: L-Tryptophan + Oxygen + NADPH + H+ = N-Hydroxy-L-tryptophan + NADP+ + H2O.
90491	N-hydroxy-L-tryptophan,NADPH:oxygen oxidoreductase (N-hydroxylating)	F	Catalyzes the reaction: N-Hydroxy-L-tryptophan + Oxygen + NADPH + H+ = N,N-Dihydroxy-L-tryptophan + NADP+ + H2O.
90492	N,N-Dihydroxy-L-tryptophan decarboxylase activity	F	Catalyzes the reaction: N,N-Dihydroxy-L-tryptophan = Indole-3-acetaldehyde oxime + CO2 + H2O.
90493	catecholamine uptake	P	The directed movement of catecholamine into a cell.
90494	dopamine uptake	P	The directed movement of dopamine into a cell.
90495	low-density lipoprotein particle disassembly	P	The disaggregation of a low-density lipoprotein particle into its constituent components.
90496	mesenchyme migration involved in limb bud formation	P	The migration of mesenchymal tissue that contributes to the formation of a limb bud.
90497	mesenchymal cell migration	P	The orderly movement of a mesenchymal cell from one site to another, often during the development of a multicellular organism.
90498	extrinsic component of Golgi membrane	C	The component of a Golgi membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
90499	pimelyl-[acyl-carrier protein] methyl ester esterase activity	F	Catalysis of the reaction: pimelyl-[acyl-carrier protein] methyl ester + H2O = pimelyl-[acyl-carrier protein] + methanol.
90500	endocardial cushion to mesenchymal transition	P	A transition where an endocardial cushion cell loses apical/basolateral polarity, severs intercellular adhesive junctions, degrades basement membrane components and becomes a migratory mesenchymal cell.
90501	RNA phosphodiester bond hydrolysis	P	The RNA metabolic process in which the phosphodiester bonds between ribonucleotides are cleaved by hydrolysis.
90502	RNA phosphodiester bond hydrolysis, endonucleolytic	P	The chemical reactions and pathways involving the hydrolysis of internal 3',5'-phosphodiester bonds in one or two strands of ribonucleotides.
90503	RNA phosphodiester bond hydrolysis, exonucleolytic	P	The chemical reactions and pathways involving the hydrolysis of terminal 3',5'-phosphodiester bonds in one or two strands of ribonucleotides.
90504	epiboly	P	The expansion of one cell sheet over other cells or yolk.
90505	epiboly involved in wound healing	P	The expansion of one cell sheet over other cells involved in wound healing.
90506	axillary shoot meristem initiation	P	A developmental process that results in the initiation of an axillary shoot meristem. An axillary shoot meristem is a shoot meristem formed in the axil of a leaf.
90507	phenylethylamine metabolic process involved in synaptic transmission	P	The chemical reactions and pathways involving phenylethylamine that contribute to synaptic transmission.
90508	phenylethylamine biosynthetic process involved in synaptic transmission	P	The chemical reactions and pathways resulting in the formation of phenylethylamine that contribute to synaptic transmission.
90509	nickel cation import into cell	P	The directed movement of nickel cations from outside of a cell into the intracellular region of a cell..
90510	anticlinal cell division	P	A cell division process where the division plane is perpendicular to the surface of the organ. It adds cells to the existing cell layer or cell file.
90511	periclinal cell division	P	A cell division process where the division plane is parallel to the surface of the organ. It creates a new cell layer or cell file.
90512	eisosome membrane domain/MCC	C	A plasma membrane part that is composed of a furrow-like plasma membrane domain and associated integral transmembrane proteins.
90513	L-histidine transmembrane import into vacuole	P	The directed movement of L-histidine into the vacuole across the vacuolar membrane.
90514	L-tyrosine transmembrane import into vacuole	P	The directed movement of L-tyrosine into the vacuole across the vacuolar membrane.
90515	L-glutamate transmembrane import into vacuole	P	The directed movement of L-glutamate into the vacuole across the vacuolar membrane.
90516	L-serine transmembrane import into vacuole	P	The directed movement of L-serine into the vacuole across the vacuolar membrane.
90517	L-lysine transmembrane import into vacuole	P	The directed movement of L-lysine into the vacuole across the vacuolar membrane.
90518	L-arginine transmembrane import into vacuole	P	The directed movement of L-arginine into the vacuole across the vacuolar membrane.
90519	anoxia protection	P	Any process in which an organism or cell protects itself from anoxia, which may also result in resistance to repeated exposure to anoxia.
90520	sphingolipid mediated signaling pathway	P	A series of molecular signals mediated by a sphingolipid.
90521	glomerular visceral epithelial cell migration	P	The orderly movement of a podocyte from one site to another, often during the development of a multicellular organism or multicellular structure. A podocyte is a specialized kidney epithelial cell.
90522	vesicle tethering involved in exocytosis	P	The initial long-distance interaction between secretory vesicles and exocytotic sites on target membranes resulting in the capture and stabilization of vesicles prior to SNARE-mediated docking and fusion.
90523	cytochrome-b5 reductase activity, acting on NADPH	F	Catalysis of the reaction: NADPH + H+ + 2 ferricytochrome b(5) = NADP+ + 2 ferrocytochrome b(5).
90524	cytochrome-b5 reductase activity, acting on NADH	F	Catalysis of the reaction: NADH + H+ + 2 ferricytochrome b(5) = NAD+ + 2 ferrocytochrome b(5).
90525	regulation of glycolysis involved in cellular glucose homeostasis	P	Any process that modulates the frequency, rate or extent of glycolysis as an integral part of cellular glucose homeostasis.
90526	regulation of gluconeogenesis involved in cellular glucose homeostasis	P	Any process that modulates the frequency, rate or extent of gluconeogenesis as an integral part of cellular glucose homeostasis.
90527	actin filament reorganization	P	A process that is carried out at the cellular level which results in dynamic structural changes to the arrangement of actin filaments.
90528	smooth septate junction assembly	P	The assembly of a smooth septate junction, a septate junction that lacks the regular arrays of electron-dense septae found in pleated septate junctions.
90529	cell septum assembly	P	The assembly and arrangement of a cellular component that is composed of peptidoglycan and often chitin in addition to other materials and usually forms perpendicular to the long axis of a cell or hypha. It grows centripetally from the cell wall to the center of the cell and often functions in the compartmentalization of a cell into two daughter cells.
90531	L-ascorbic acid biosynthetic process via GDP-alpha-D-mannose	P	The chemical reactions and pathways resulting in the formation of L-ascorbic acid via the intermediate GDP-alpha-D-mannose.
90532	L-ascorbic acid biosynthetic process via UDP-alpha-D-glucuronate	P	The chemical reactions and pathways resulting in the formation of L-ascorbic acid via the intermediate UDP-alpha-D-glucuronate.
90533	cation-transporting ATPase complex	C	Protein complex that carries out the reaction: ATP + H2O + cation(out) = ADP + phosphate + cation(in).
90534	calcium ion-transporting ATPase complex	C	Protein complex that carries out the reaction: ATP + H2O + Ca2+(out) = ADP + phosphate + Ca2+(in).
90535	WICH complex	C	An ISWI complex that contains an ATPase subunit of the ISWI family (specifically SNF2H in mammals, which contain two ISWI homologs) and WSTF (Williams Syndrome Transcription Factor). WICH plays roles in regulation of RNAP I and III transcription and in DNA replication and repair.
90536	NoRC complex	C	An ISWI complex that contains an ATPase subunit of the ISWI family (specifically SNF2H in mammals, which contain two ISWI homologs) and a Tip5 homolog. In mammals, NoRC is involved in regulation of transcription from RNAP I and RNA polymerase III promoters.
90537	CERF complex	C	An ISWI complex that contains an ATPase subunit of the ISWI family (specifically SNF2L in mammals, which contain two ISWI homologs) and a CECR2 homolog. In mammals, CERF is involved in regulation of transcription from RNA polymerase II promoters.
90538	peptide pheromone secretion	P	The regulated release of a peptide pheromone from a cell.
90539	peptide pheromone export by transmembrane transport	P	The directed movement of a peptide pheromone across a membrane and out of a cell.
90540	bacterial cellulose biosynthetic process	P	The chemical reactions and pathways resulting in the formation of cellulose, a linear beta1-4 glucan of molecular mass 50-400 kDa with the pyranose units in the -4C1 conformation, as it occurs in certain types of bacteria, mainly Acetobacter, Sarcina ventriculi and Agrobacteria.
90541	MIT domain binding	F	Interacting selectively and non-covalently with the MIT domain of a protein. The MIT domain is found in vacuolar sorting proteins, spastin (probable ATPase involved in the assembly or function of nuclear protein complexes), and a sorting nexin, which may play a role in intracellular trafficking.
90542	ELYC domain binding	F	Interacting selectively and non-covalently with the ELYC domain of a protein. The ELYC domain is an approximately 150 amino acid sequence which contains a highly conserved tetrapeptide sequence, ELYC.
90543	Flemming body	C	A cell part that is the central region of the midbody characterized by a gap in alpha-tubulin staining. It is a dense structure of antiparallel microtubules from the central spindle in the middle of the intercellular bridge.
90544	BAF-type complex	C	A SWI/SNF-type complex that contains a subunit from the BAF (Brahma-Associated Factor) family.
90545	CHD-type complex	C	A SWI/SNF-type complex that contains a subunit from the CHD(Chromodomain helicase DNA-binding) family. The CHD family is characterized by two signature sequence motifs: tandem chromodomains located in the N-terminal region, and the SNF2-like ATPase domain located in the central region of the protein structure.
90546	chlorophyll fluorescence	P	The process by which excess light energy absorbed by chlorophyll and not used to drive photosynthesis is re-emitted as light.
90547	response to low humidity	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of low humidity stimulus, reduced moisture in the atmosphere.
90548	response to nitrate starvation	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a starvation stimulus, deprivation of nitrate.
90549	response to carbon starvation	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a starvation stimulus, deprivation of a carbon source.
90550	response to molybdenum starvation	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a starvation stimulus, deprivation of molybdenum.
90551	response to manganese starvation	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a starvation stimulus, deprivation of manganese.
90552	unicellular trichome apex	C	A cell projection part that is the apical most portion of a unicellular trichome.
90553	unicellular trichome tip	C	A cell projection part that is the apical most portion of a unicellular trichome apex.
90554	phosphatidylcholine-translocating ATPase activity	F	Catalysis of the movement of phosphatidylcholine from one membrane bilayer leaflet to the other, driven by the hydrolysis of ATP.
90555	phosphatidylethanolamine-translocating ATPase activity	F	Catalysis of the movement of phosphatidylethanolamine from one membrane bilayer leaflet to the other, driven by the hydrolysis of ATP.
90556	phosphatidylserine-translocating ATPase activity	F	Catalysis of the movement of phosphatidylserine from one membrane bilayer leaflet to the other, driven by the hydrolysis of ATP.
90557	establishment of endothelial intestinal barrier	P	The establishment of a barrier between endothelial cell layers of the intestine to exert specific and selective control over the passage of water and solutes, thus allowing formation and maintenance of compartments that differ in fluid and solute composition.
90558	plant epidermis development	P	The process whose specific outcome is the progression of the plant epidermis over time, from its formation to the mature structure.
90559	regulation of membrane permeability	P	Any process that modulates the frequency, rate or extent of the passage or uptake of molecules by a membrane.
90560	2-(3-amino-3-carboxypropyl)histidine synthase activity	F	Catalysis of the reaction S-adenosyl-L-methionine + L-histidine-[translation elongation factor 2] = S-methyl-5-thioadenosine + 2-[(3S)-3-amino-3-carboxypropyl]-L-histidine-[translation elongation factor 2].
90561	nuclear migration during mitotic telophase	P	The dynein-driven microtubule based nuclear migration, whereby daughter nuclei are positioned away from the cell division site prior to cytokinesis.
90562	protein-N(PI)-phosphohistidine-N,N'-diacetylchitobiose phosphotransferase system transporter activity	F	Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + N,N'-diacetylchitobiose(out) = protein histidine + N,N'-diacetylchitobiose phosphate(in).
90563	protein-phosphocysteine-sugar phosphotransferase activity	F	Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein S-phosphocysteine + sugar(out) = protein cysteine + sugar phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.
90564	protein-phosphocysteine-glucose phosphotransferase system transporter activity	F	Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein S-phosphocysteine + glucose(out) = protein cysteine + glucose phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.
90565	protein-phosphocysteine-mannitol phosphotransferase system transporter activity	F	Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein S-phosphocysteine + mannitol(out) = protein cysteine + mannitol phosphate(in). This differs from primary and secondary active transport in that the solute is modified during transport.
90566	protein-phosphocysteine-N,N'-diacetylchitobiose phosphotransferase system transporter activity	F	Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein S-phosphocysteine + N,N'-diacetylchitobiose(out) = protein cysteine + N,N'-diacetylchitobiose phosphate(in).
90567	reproductive shoot system development	P	The process whose specific outcome is the progression of a reproductive shoot system over time, from its formation to the mature structure.
90568	nuclear transcriptional repressor complex	C	A protein complex, located in the nucleus, that possesses activity that prevents or downregulates transcription.
90569	cytoplasmic transcriptional repressor complex	C	A protein complex, located in the cytoplasm, that possesses activity that prevents or downregulates transcription.
90570	RNA polymerase I transcription repressor complex	C	A protein complex, located in the nucleus, that possesses activity that prevents or downregulates transcription from a RNA polymerase I promoter.
90571	RNA polymerase II transcription repressor complex	C	A protein complex, located in the nucleus, that possesses activity that prevents or downregulates transcription from a RNA polymerase II promoter.
90572	RNA polymerase III transcription repressor complex	C	A protein complex, located in the nucleus, that possesses activity that prevents or downregulates transcription from a RNA polymerase III promoter.
90573	RNA polymerase IV transcription repressor complex	C	A protein complex, located in the nucleus, that possesses activity that prevents or downregulates transcription from a RNA polymerase IV promoter.
90574	RNA polymerase V transcription repressor complex	C	A protein complex, located in the nucleus, that possesses activity that prevents or downregulates transcription from a RNA polymerase V promoter.
90575	RNA polymerase II transcription factor complex	C	A transcription factor complex that acts at promoters of genes transcribed by RNA polymerase II.
90576	RNA polymerase III transcription factor complex	C	A transcription factor complex that acts at promoters of genes transcribed by RNA polymerase III.
90577	RNA polymerase IV transcription factor complex	C	A transcription factor complex that acts at promoters of genes transcribed by RNA polymerase IV.
90578	RNA polymerase V transcription factor complex	C	A transcription factor complex that acts at promoters of genes transcribed by RNA polymerase V.
90579	dsDNA loop formation	P	The formation and maintenance of DNA loops that juxtapose separated regions on the same dsDNA molecule.
90580	phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands	F	Catalysis of the hydrolytic removal of phosphoglycolate from the 3'-terminus of a 3'-phosphoglycolate-terminated oligonucleotides.
90581	protein-phosphocysteine-mannosylglycerate-phosphotransferase system transporter activity	F	Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein S-phosphocysteine + mannosylglycerate(out) = protein cysteine + mannosylglycerate phosphate(in).
90582	protein-phosphocysteine-D-fructose-phosphotransferase system transporter activity	F	Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein S-phosphocysteine + D-fructose(out) = protein cysteine + D-fructose-1-phosphate(in).
90583	protein-phosphocysteine-D-sorbitol-phosphotransferase system transporter activity	F	Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein S-phosphocysteine + D-sorbitol(out) = protein cysteine + D-sorbitol-1-phosphate(in).
90584	protein-phosphocysteine-galactitol-phosphotransferase system transporter activity	F	Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein S-phosphocysteine + galactitol(out) = protein cysteine + galactitol-6-phosphate(in).
90585	protein-phosphocysteine-L-ascorbate-phosphotransferase system transporter activity	F	Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein S-phosphocysteine + L-ascorbate(out) = protein cysteine + L-ascorbate-6-phosphate(in).
90586	protein-phosphocysteine-N-acetylglucosamine phosphotransferase system transporter activity	F	: Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein S-phosphocysteine + N-acetylglucosamine (out) = protein cysteine + N-acetylglucosamine-6-phosphate (in).
90587	protein-phosphocysteine-glucosamine phosphotransferase system transporter activity	F	Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein S-phosphocysteine + glucosamine (out) = protein cysteine + glucosamine-6-phosphate (in).
90588	protein-phosphocysteine-N-acetylmuramate phosphotransferase system transporter activity	F	Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein S-phosphocysteine + N-acetylmuramate (out) = protein cysteine + N-acetylmuramate-6-phosphate (in).
90589	protein-phosphocysteine-trehalose phosphotransferase system transporter activity	F	Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein S-phosphocysteine + trehalose (out) = protein cysteine + trehalose-6-phosphate (in).
90590	protein-N(PI)-phosphohistidine-D-glucosamine phosphotransferase system transporter activity	F	Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + D-glucosamine(out) = protein histidine + glucosamine-6-phosphate(in).
90591	protein-N(PI)-phosphohistidine-N-acetyl-mannosamine phosphotransferase system transporter activity	F	Catalysis of the PEP-dependent, phosphoryl transfer-driven transport of substances across a membrane. The transport happens by catalysis of the reaction: protein N-phosphohistidine + N-acetyl-mannosamine(out) = protein histidine +N-acetyl- mannosamine-6-phosphate(in).
90592	DNA synthesis involved in DNA replication	P	Synthesis of DNA that is a part of the process of duplicating one or more molecules of DNA.
90593	peptidyl-histidine autophosphorylation	P	The phosphorylation by a protein of one or more of its own histidine residues, or a histidine residue on an identical protein.
90594	inflammatory response to wounding	P	The immediate defensive reaction by vertebrate tissue to injury caused by chemical or physical agents.
90595	acetyl-CoA:L-lysine N6-acetyltransferase	F	Catalysis of the reaction: L-lysine + acetyl-CoA = N6-acetyl-L-lysine + CoA + H(+).
90596	sensory organ morphogenesis	P	Morphogenesis of a sensory organ. A sensory organ is defined as a tissue or set of tissues that work together to receive and transmit signals from external or internal stimuli. Morphogenesis is the process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.
90597	nematode male tail mating organ morphogenesis	P	The process in which the anatomical structures of the nematode male tail mating organ are generated and organized. The male tail is a sensory organ required for mating and, in C. elegans, consists of ray sensilla, an acellular cuticular fan, a sensory hook, and protracting, copulatory spicules.
90598	male anatomical structure morphogenesis	P	The processes by which anatomical structures that are only present in the male organism are generated and organized.
90599	alpha-glucosidase activity	F	Catalysis of the hydrolysis of terminal, non-reducing alpha-linked alpha-D-glucose residue with release of alpha-D-glucose.
90600	alpha-1,3-glucosidase activity	F	Catalysis of the hydrolysis of terminal, non-reducing alpha-(1->3)-linked alpha-D-glucose residues with release of alpha-D-glucose.
90601	enucleation	P	The process in which nucleated precursor cells lose their nucleus.
90602	sieve element enucleation	P	The process in which nucleated precursor cells lose their nucleus as part of sieve element differentiation. The nuclear contents are released and degraded in the cytoplasm at the same time as other organelles are rearranged and the cytosol is degraded.
90603	sieve element differentiation	P	The process whereby a relatively unspecialized cell acquires specialized features of a sieve element.
90604	surface biofilm formation	P	A process in which planktonically growing microorganisms grow at the surface of a liquid-air interface and produce extracellular polymers that facilitate matrix formation, resulting in a change in the organisms' growth rate and gene transcription.
90605	submerged biofilm formation	P	A process in which planktonically growing microorganisms aggregate and grow on solid substrates under the flow of a liquid and produce extracellular polymers that facilitate attachment and matrix formation, resulting in a change in the organisms' growth rate and gene transcription.
90606	single-species surface biofilm formation	P	A process in which planktonically growing microorganisms of the same species grow at the surface of a liquid-air interface and produce extracellular polymers that facilitate matrix formation, resulting in a change in the organisms' growth rate and gene transcription.
90607	multi-species surface biofilm formation	P	A process in which planktonically growing microorganisms of different species grow at the surface of a liquid-air interface and produce extracellular polymers that facilitate matrix formation, resulting in a change in the organisms' growth rate and gene transcription.
90608	multi-species submerged biofilm formation	P	A process in which planktonically growing microorganisms of different species aggregate and grow on solid substrates under the flow of a liquid and produce extracellular polymers that facilitate attachment and matrix formation, resulting in a change in the organisms' growth rate and gene transcription.
90609	single-species submerged biofilm formation	P	A process in which planktonically growing microorganisms of the same species aggregate and grow on solid substrates under the flow of a liquid and produce extracellular polymers that facilitate attachment and matrix formation, resulting in a change in the organisms' growth rate and gene transcription.
90610	bundle sheath cell fate specification	P	The process in which a cell becomes capable of differentiating autonomously into a bundle sheath cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.
90611	ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway	P	The chemical reactions and pathways resulting in the breakdown of a protein or peptide, via the multivesicular body (MVB) sorting pathway; proteins are sorted into MVBs, and delivered to a lysosome/vacuole for degradation. This process is independent of ubiquitination.
90612	cAMP deaminase activity	F	Catalysis of the reaction: cyclic adenosine monophosphate + H2O = cyclic inosine monophosphate + NH3.
90613	5'-deoxyadenosine deaminase activity	F	Catalysis of the reaction: 5'deoxyadenosine + H2O = 5'deoxyinosine + NH3.
90614	5'-methylthioadenosine deaminase activity	F	Catalysis of the reaction: 5'methyl thioadenosine + H2O = 5'methyl thioinosine + NH3.
90615	mitochondrial mRNA processing	P	Steps involved in processing precursor RNAs arising from transcription of operons in the mitochondrial genome into mature mRNAs.
90616	mitochondrial mRNA 3'-end processing	P	Any process involved in forming the mature 3' end of an mRNA molecule that derives from the mitochondrial genome.
90617	mitochondrial mRNA 5'-end processing	P	Any process involved in forming the mature 5' end of an mRNA molecule that derives from the mitochondrial genome.
90618	DNA clamp unloading	P	The process of removing the PCNA complex from DNA when Okazaki fragments are completed or the replication fork terminates.
90619	meiotic spindle pole	C	Either of the ends of a meiotic spindle, a spindle that forms as part of meiosis, where spindle microtubules are organized; usually contains a microtubule organizing center and accessory molecules, spindle microtubules and astral microtubules.
90624	endoribonuclease activity, cleaving miRNA-paired mRNA	F	Catalysis of the endonucleolytic cleavage of the mRNA in a double-stranded RNA molecule formed by the base pairing of an mRNA with an miRNA.
90625	mRNA cleavage involved in gene silencing by siRNA	P	The process in which small interfering RNAs (siRNAs) direct the cleavage of target mRNAs. Once incorporated into a RNA-induced silencing complex (RISC), a siRNA will typically direct cleavage by base pairing with perfect or near-perfect complementarity to the target mRNA.
90626	plant epidermis morphogenesis	P	The process in which the anatomical structures of the plant epidermis are generated and organized.
90627	plant epidermal cell differentiation	P	The process in which a relatively unspecialized cell acquires specialized features of a plant epidermal cell.
90628	plant epidermal cell fate specification	P	The process in which a cell becomes capable of differentiating autonomously into a plant epidermal cell in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed.
90629	lagging strand initiation	P	The process in which the synthesis of DNA from a template strand in a net 3' to 5' direction is started.
90630	activation of GTPase activity	P	Any process that initiates the activity of an inactive GTPase through the replacement of GDP by GTP.
90631	pre-miRNA transporter activity	F	Enables the directed movement of pre-miRNAs between the nucleus and the cytoplasm of a cell.
90632	N-glycolylneuraminic acid (Neu5Gc) cytidylyltransferase activity	F	Catalysis of the reaction: CTP + Neu5Gc = diphosphate + CMP-Neu5Gc.
90633	keto-deoxynonulosonic acid (KDN) cytidylyltransferase activity	F	Catalysis of the reaction: CTP + KDN = diphosphate + CMP-KDN.
90634	microglial cell mediated cytotoxicity	P	The directed killing of a target cell by a microglial cell.
90635	extracellular core region of desmosome	C	The desmosomal part containing the desmosomal cadherins, desmogleins and desmocollins, that establish contact and adhere to neighboring cells in a Ca2+-dependent manner.
90636	outer dense plaque of desmosome	C	The desmosomal part containing plakoglobins, plakophilins, the N-termini of desmoplakins, as well as the cytoplasmic tails of the desmosomal cadherins, which together attach the plaque to the plasma membrane.
90637	inner dense plaque of desmosome	C	The desmosomal part containing the C-termini of desmoplakins which interact with the keratin intermediate filaments, serving to tether the intermediate filaments to the plasma membrane.
90638	phosphatidylcholine biosynthesis from phosphatidylethanolamine	P	The phosphatidylcholine biosynthetic process that depends on direct conversion of the phosphatidyl-base phosphatidylethanolamine to phosphatidylcholine by successive methylations.
90639	phosphatidylcholine biosynthesis from choline and CDP-diacylglycerol	P	The phosphatidylcholine biosynthetic process that involves a one-step direct condensation of choline with CDP-diacylglycerol to form phosphatidylcholine.
90640	phosphatidylcholine biosynthesis from sn-glycero-3-phosphocholine	P	The phosphatidylcholine biosynthetic process that involves the two-step acylation of sn-glycero-3-phosphocholine to a phosphatidylcholine.
90641	microsporidian-type endospore	C	The middle layer in a microsporidian spore wall that lies under the exospore and outside the plasma membrane, containing chitin and proteins.
90642	microsporidian-type exospore	C	The dense, protein rich outermost layer of a microsporidian spore wall that lies above the endospore.
90643	inflorescence phyllotactic patterning	P	The radial pattern formation process that results in the formation of flowers around a central axis in an inflorescence meristem.
90644	age-related resistance	P	An innate immune response that is positively correlated with host plant development. As a plant develops, its innate resistance to pathogenic infections increases. The mechanisms involved in age-related resistance differ in nature or in aspects of regulation from the hypersensitive response (HR), systemic acquired resistance (SAR), or induced systemic resistance (ISR).
90646	mitochondrial tRNA processing	P	The process in which a pre-tRNA molecule is converted to a mature tRNA, ready for addition of an aminoacyl group, in the mitochondrion.
90647	modulation of age-related behavioral decline	P	Any process that modulates the processes that arise as an organism progresses toward the end of its lifespan that results in a decline in behavioral activities such as locomotory behavior, and learning or memory.
90648	response to environmental enrichment	P	Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the provision of a combination of complex inanimate and social stimulations in the organism's housing environment.
90649	response to oxygen-glucose deprivation	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the deprivation of oxygen and glucose.
90650	cellular response to oxygen-glucose deprivation	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the deprivation of oxygen and glucose.
90651	apical cytoplasm	C	The region of the cytoplasm located at the apical side of the cell. Used in reference to animal polarized epithelial cells.
90652	basolateral cytoplasm	C	The region of the cytoplasm located at the basolateral side of the cell. Used in reference to animal polarized epithelial cells.
90653	apical recycling endosome	C	Tubulo-vesicular structure located in the apical cytoplasm that participates in apical cargo recycling in polarized epithelial cells.
90654	basolateral recycling endosome	C	Tubulo-vesicular structure located in the basolateral cytoplasm that participates in basolateral cargo recycling in polarized epithelial cells.
90655	double-stranded/single-stranded junction telomeric DNA binding	F	Interacting selectively and non-covalently with the junction formed at the point where double-stranded telomeric DNA becomes a single-stranded G-rich telomeric DNA 3' overhang.
90656	t-circle formation	P	A telomere maintenance process that results in the formation of a telomeric circle, or t-circle. A t-circle is an extrachromosomal duplex or single-stranded circular DNA molecule composed of t-arrays. T-circles are involved in the control of telomere length via alternative-lengthening of telomeres (ALT) pathway and telomere rapid deletion (TRD).
90657	telomeric loop disassembly	P	The telomere maintenance process in which telomeric loops are disassembled to permit efficient telomere replication.
90658	cone matrix sheath	C	A biochemically and structurally distinct domain of the retinal interphotoreceptor matrix that is specifically associated with cone photoreceptor cell inner and outer segments.
90659	walking behavior	P	The behavior of an organism relating to the progression of that organism along the ground by the process of lifting and setting down each leg.
90660	cerebrospinal fluid circulation	P	The neurological system process driven by motile cilia on ependymal cells of the brain by which cerebrospinal fluid circulates from the sites of secretion to the sites of absorption. In ventricular cavities, the flow is unidirectional and rostrocaudal, in subarachnoid spaces, the flow is multi-directional.
90661	box H/ACA telomerase RNP complex	C	A box H/ACA ribonucleoprotein complex that contains the RNA component of vertebrate telomerase, the enzyme essential for the replication of chromosome termini in most eukaryotes. This ribonucleoprotein complex is a structural box H/ACA RNP, which does not have the catalytic pseudouridylation function shared by the majority of H/ACA RNPs present in the cell.
90662	ATP hydrolysis coupled transmembrane transport	P	The transport of molecules across a membrane and against an electrochemical gradient, using energy from ATP hydrolysis.
90663	galanin-activated signaling pathway	P	The series of molecular signals generated as a consequence of the peptide neurotransmitter galanin binding to a cell surface receptor.
90664	response to high population density	P	Any process that results in a change in state or activity of a cell or a multicellular organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a higher than normal number of multicellular organisms living per unit area.
90665	glycoprotein complex	C	A protein complex containing at least one glycosylated protein, may be held together by both covalent and noncovalent bonds.
90666	scaRNA localization to Cajal body	P	A process in which a small Cajal body-specific RNA is transported to, or maintained in, a Cajal body.
90667	cell chemotaxis to vascular endothelial growth factor	P	The directed movement of a motile cell in response to the presence of vascular endothelial growth factor (VEGF).
90668	endothelial cell chemotaxis to vascular endothelial growth factor	P	The directed movement of an endothelial cell in response to the presence of vascular endothelial growth factor (VEGF).
90669	telomerase RNA stabilization	P	Prevention of degradation of telomerase RNA (TERC) molecules.
90670	RNA localization to Cajal body	P	A process in which an RNA is transported to, or maintained in, a Cajal body.
90671	telomerase RNA localization to Cajal body	P	A process in which telomerase RNA (TERC) is transported to, or maintained in, a Cajal body.
90672	telomerase RNA localization	P	Any process in which telomerase RNA is transported to, or maintained in, a specific location.
90673	endothelial cell-matrix adhesion	P	The binding of an endothelial cell to the extracellular matrix via adhesion molecules.
90674	endothelial cell-matrix adhesion via fibronectin	P	The binding of an endothelial cell to the extracellular matrix via fibronectin.
90675	intermicrovillar adhesion	P	The biological adhesion process by which adjacent microvilli attach to each other through Ca(2+)-dependent adhesion links made of protocadherin-24 and mucin-like protocadherin.
90676	calcium ion transmembrane transport via low voltage-gated calcium channel	P	A process in which a calcium ion is transported from one side of a membrane to the other by means of a low voltage-gated calcium channel.
90677	reversible differentiation	P	A phenotypic switching process where a cell reversibly differentiates and dedifferentiates from one cell type into another.
90678	cell dedifferentiation involved in phenotypic switching	P	A cell dedifferentiation process that is a part of a reversible switch of a cell from one cell type or form to another, at a frequency above the expected frequency for somatic mutations.
90679	cell differentiation involved in phenotypic switching	P	A cell differentiation process that is a part of a reversible switch of a cell from one cell type or form to another, at a frequency above the expected frequency for somatic mutations.
90680	disruption by virus of host outer membrane	P	A process by which a virus has a negative effect on the functioning of a host outer membrane.
90681	GPCR taste receptor activity	F	A G-protein coupled receptor activity that is responsible for the sense of taste.
90682	GPCR bitter taste receptor activity	F	A G-protein coupled receptor activity that is responsible for the sense of bitter taste.
90683	GPCR sweet taste receptor activity	F	A G-protein coupled receptor activity that is responsible for the sense of sweet taste.
90684	contact chemoreceptor activity	F	A non-GPCR transmembrane signaling receptor activity that is responsible for contact chemoreception.
90685	RNA localization to nucleus	P	A macromolecular localization process in which RNA is transported to and maintained in a location within the nucleus.
90686	glycine betaine-activated nonselective monovalent cation channel activity	F	Enables the transmembrane transfer of a monovalent cation by a channel that opens when glycine betaine has been bound by the channel complex or one of its constituent parts.
90687	activation of meiosis I spindle assembly checkpoint	P	Any process that starts the inactive process of a meiosis I cell cycle spindle assembly checkpoint.
90688	cleavage furrow rim	C	The 'trough' of the cleavage furrow. This is the part of the cleavage furrow closest to the contractile ring.
90689	cleavage furrow leading edge	C	The part of the cleavage furrow closest to the cell surface.
90691	formation of plant organ boundary	P	The regionalization process that specifies plant organ primordium boundaries resulting in a restriction of organogenesis to a limited spatial domain and keeping the organ separate from surrounding tissues.
90692	mitochondrial membrane scission site	C	The site on the mitochondrial membrane where the separation of a single continuous mitochondrial membrane into two membranes occurs as a final step in mitochondrial fission.
90693	plant organ senescence	P	The process that occurs in a plant organ near the end of its active life that is associated with the dismantling of cell components and membranes, and an overall decline in metabolism.
90694	Scc2-Scc4 cohesin loading complex	C	A eukaryotically conserved heterodimeric protein complex (comprising adherin and the chromatid cohesion factor MAU2/Scc4/Ssl3) required for the loading of a cohesin, complex onto DNA.
90695	Wpl/Pds5 cohesin loading/unloading complex	C	A eukaryotically conserved heterodimeric protein complex (comprising Wings apart-like protein and the Pds5 Armadillo repeat cohesin associated protein) involved in the loading and unloading of a cohesin complex onto DNA.
90696	post-embryonic plant organ development	P	Development, taking place during the post-embryonic phase of a plant tissue or tissues that work together to perform a specific function or functions. Development pertains to the process whose specific outcome is the progression of a structure over time, from its formation to the mature structure. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.
90697	post-embryonic plant organ morphogenesis	P	Morphogenesis, during the post-embryonic phase, of a plant tissue or tissues that work together to perform a specific function or functions. Morphogenesis pertains to process in which anatomical structures are generated and organized. Organs are commonly observed as visibly distinct structures, but may also exist as loosely associated clusters of cells that work together to perform a specific function or functions.
90698	post-embryonic plant morphogenesis	P	The process, occurring after plant embryonic development, by which anatomical structures are generated and organized.
90699	correction of merotelic kinetochore attachment, meiosis I	P	The cell cycle process that corrects the anomalous association of a single chromatid kinetochore with mitotic spindle microtubules emanating from both spindle poles at meiosis I, and would, if uncorrected result in the separation of sister chromatids at meiosis I.
90700	maintenance of plant organ identity	P	The process in which the identity of a plant organ is maintained. Identity is considered to be the aggregate of characteristics by which a structure is recognized.
90701	specification of plant organ identity	P	The regionalization process in which the identity of a plant organ primordium is specified. Identity is considered to be the aggregate of characteristics by which a structure is recognized.
90702	non-reproductive fruiting body development	P	The process whose specific outcome is the progression of a non-reproductive fruiting body over time, from its formation to the mature structure. A non-reproductive fruiting body is a colonial multicellular structure consisting of co-operating unicellular organisms, some of which are spores. An example of such a process is found in Dictyostelium discoideum and Myxococcus xanthus colonies.
90704	nicotinate-O-glucosyltransferase activity	F	Catalysis of the reaction: nicotinate + UDP-D-glucose = O-D-glucosylnicotinate + UDP.
90705	trichome papilla	C	A plant cell papilla that is part of a trichome cell.
90706	specification of plant organ position	P	The regionalization process in which information that determines the correct position at which plant organ primordia are formed is generated and perceived resulting in correct positioning of the new plant organ.
90707	establishment of plant organ orientation	P	The process that determines the orientation of a plant organ or tissue with reference to an axis.
90708	specification of plant organ axis polarity	P	The process in which the polarity of a plant organ axis is specified.
90709	regulation of timing of plant organ formation	P	Any process that modulates the rate, frequency or extent of plant organ formation at a consistent predetermined time point during development.
90710	phosphomevalonate decarboxylase activity	F	Catalysis of the reaction: ATP + (R)-mevalonate 5-phosphate = ADP + isopentenyl phosphate + CO2 + phosphate.
90711	FMN hydrolase activity	F	Catalysis of the reaction: FMN + H2O = riboflavin + phosphate.
90712	basal pole of outer hair cell	C	The end of the outer hair cell which receives and transmits neural signals.
90713	immunological memory process	P	Any process of the immune system that can contribute to the formation of immunological memory or an immune response based upon activation of immunological memory.
90714	innate immunity memory response	P	An immune response mediated by the innate immune system and directed against a previously encountered immunologic stimulus, being quicker and quantitatively better compared with the initial response to that stimulus.
90715	immunological memory formation process	P	Any immunological memory process that can contribute to the formation of immunological memory.
90716	adaptive immune memory response	P	An immune response directed against a previously encountered antigen, being quicker and quantitatively better compared with the primary response.
90717	adaptive immune memory response involving T cells and B cells	P	An immune response mediated by reactivated memory T cells and B cells and directed against a previously encountered antigen, being quicker and quantitatively better compared with the primary response.
90718	adaptive immune effector response	P	An adaptive immune response that involves one or more immune effector processes and takes place during the effector phase of the adaptive immune response.
90719	adaptive immune effector response involving T cells and B lineage cells	P	An adaptive immune effector response involving T cells and B lineage cells. In the case of B lineage cells, the effector cells are the antibody secreting plasma cells whereas for T cells the effector cells may be helper T cells or cytotoxic T cells.
90720	primary adaptive immune response	P	An adaptive immune response against an antigen not previously encountered by immune system.
90721	primary adaptive immune response involving T cells and B cells	P	An adaptive immune response mediated by naive T or B cells against an antigen not previously encountered by immune system.
90722	receptor-receptor interaction	F	The aggregation, arrangement and bonding together of two or more different receptor complexes that individually undergo combination with a hormone, neurotransmitter, drug or intracellular messenger to form a higher level receptor complex. The formation of the higher level complex initiates a change in cell function.
90723	growth cone part	C	Any constituent part of a growth cone, the migrating motile tip of a growing nerve cell axon or dendrite.
90724	central region of growth cone	C	The center of the migrating motile tip of a growing nerve cell axon or dendrite.
90725	peripheral region of growth cone	C	The non-central region or periphery of the migrating motile tip of a growing nerve cell axon or dendrite.
90726	cortical dynamic polarity patch	C	A region of the cell cortex that contains a higher concentration of growth polarity factors than the surrounding cortex and that changes position over time. An example is found in fission yeast cells during early mating, in which the GTPase Cdc42 dynamically to discrete zones within the cortex prior to shmoo formation.
90727	positive regulation of brood size	P	Any process that increases brood size. Brood size is the number of progeny that survive embryogenesis and are cared for at one time.
90728	negative regulation of brood size	P	Any process that decreases brood size. Brood size is the number of progeny that survive embryogenesis and are cared for at one time.
90729	toxin activity	F	Interacting selectively with one or more biological molecules in another organism (the "target" organism), initiating pathogenesis (leading to an abnormal, generally detrimental state) in the target organism. The activity should refer to an evolved function of the active gene product, i.e. one that was selected for. Examples include the activity of botulinum toxin, and snake venom.
90730	Las1 complex	C	A four subunit complex, that comprises all the necessary RNA processing enzymes (endonuclease, polynucleotide kinase, and exonuclease) to mediate 'cistronic rRNA transcript ITS2 (internal transcribed spacer) cleavage' (GO:0000448).
93001	glycolysis from storage polysaccharide through glucose-1-phosphate	P	The chemical reactions and pathways resulting in the breakdown of a storage polysaccharide into pyruvate through a glucose-1-phosphate intermediate, with the concomitant production of a small amount of ATP and the reduction of NAD to NADH.
93002	response to nematicide	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nematicide stimulus. Nematicides are chemicals used to kill nematodes.
95500	acetylcholine receptor signaling pathway	P	The series of molecular signals generated as a consequence of an acetylcholine receptor binding to one of its physiological ligands.
97001	ceramide binding	F	Interacting selectively and non-covalently with any ceramide, a class of lipids that is composed of sphingosine linked to a fatty acid. Ceramides are a major component of cell membranes.
97002	mitochondrial inner boundary membrane	C	The portion of the mitochondrial inner membrane that is not invaginated to form cristae. The inner boundary membrane lies parallel to the outer membrane.
97003	adipokinetic hormone receptor activity	F	Combining with an adipokinetic hormone to initiate a change in cell activity. Adipokinetic hormones (AKHs) are peptide hormones that are involved in the mobilization of sugar and lipids from the insect fat body during energy-requiring activities such as flight and locomotion. They also contribute to hemolymph sugar homeostasis.
97004	adipokinetic hormone binding	F	Interacting selectively and non-covalently with an adipokinetic hormone. Adipokinetic hormones (AKHs) are peptide hormones that are involved in the mobilization of sugar and lipids from the insect fat body during energy-requiring activities such as flight and locomotion. They also contribute to hemolymph sugar homeostasis.
97005	adipokinetic hormone receptor binding	F	Interacting selectively and non-covalently with an adipokinetic hormone receptor. Adipokinetic hormones (AKHs) are peptide hormones that are involved in the mobilization of sugar and lipids from the insect fat body during energy-requiring activities such as flight and locomotion. They also contribute to hemolymph sugar homeostasis.
97006	regulation of plasma lipoprotein particle levels	P	Any process involved in the maintenance of internal levels of plasma lipoprotein particles within an organism.
97007	4,8,12-trimethyltrideca-1,3,7,11-tetraene synthase activity	F	Catalysis of the reaction: (EE)-geranyllinalool + NADPH + O2 = 4,8,12-trimethyl-1,3,7,11-tridecatetraene + NADP+ + 2 H2O. It is unknown whether this reaction proceeds by the direct release of the 4-carbon compound but-1-en-3-one, or whether the substrate is first degraded to C18-farnesylacetone and then cleaved to produce 4,8,12-trimethyl-1,3,7,11-tridecatetraene (TMTT) and acetone.
97008	(3E)-4,8-dimethyl-1,3,7-nonatriene synthase activity	F	Catalysis of the reaction: (E)-nerolidol + NADPH + O2 = (3E)-4,8-dimethylnona-1,3,7-triene + NADP+ + 2 H2O. It is unknown whether this reaction proceeds by the direct release of the 4-carbon compound but-1-en-3-one, or whether the substrate is first degraded to C11-geranylacetone and then cleaved to produce (3E)-4,8-dimethylnona-1,3,7-triene (DMNT) and acetone.
97009	energy homeostasis	P	Any process involved in the balance between food intake (energy input) and energy expenditure.
97010	eukaryotic translation initiation factor 4F complex assembly	P	The aggregation, arrangement and bonding together of a set of components to form the eukaryotic translation initiation factor 4F complex.
97011	cellular response to granulocyte macrophage colony-stimulating factor stimulus	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a granulocyte macrophage colony-stimulating factor stimulus.
97012	response to granulocyte macrophage colony-stimulating factor	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a granulocyte macrophage colony-stimulating factor stimulus.
97013	phagocytic vesicle lumen	C	The volume enclosed by the membrane of a phagocytic vesicle.
97014	ciliary plasm	C	All of the contents of a cilium, excluding the plasma membrane surrounding the cilium.
97015	bacterial-type flagellar cytoplasm	C	All of the contents of a bacterial-type flagellum, excluding the plasma membrane surrounding the flagellum.
97016	L27 domain binding	F	Interacting selectively and non-covalently with a L27 domain of a protein. L27 is composed of conserved negatively charged amino acids and a conserved aromatic amino acid. L27 domains can assemble proteins involved in signaling and establishment and maintenance of cell polarity into complexes by interacting in a heterodimeric manner.
97017	renal protein absorption	P	A renal system process in which proteins are taken up from the collecting ducts, glomerulus and proximal and distal loops of the nephron. In non-mammalian species, absorption may occur in related structures (e.g. protein absorption is observed in nephrocytes in Drosophila, see PMID:23264686).
97018	renal albumin absorption	P	A renal system process in which albumin is taken up from the collecting ducts, glomerulus and proximal and distal loops of the nephron.
97019	neurotransmitter receptor catabolic process	P	The chemical reactions and pathways resulting in the breakdown of neurotransmitter receptors.
97020	COPII adaptor activity	F	The binding activity of a molecule that brings together the COPII vesicle proteins and one or more other molecules, permitting them to function in a coordinated way.
97021	lymphocyte migration into lymphoid organs	P	The movement of a lymphocyte within the lymphatic system into lymphoid organs such as lymph nodes, spleen or Peyer's patches, and its subsequent positioning within defined functional compartments such as sites of cell activation by antigen.
97022	lymphocyte migration into lymph node	P	The movement of a lymphocyte within the lymphatic system into a lymph node, and its subsequent positioning within defined functional compartments such as sites of cell activation by antigen.
97023	fructose 6-phosphate aldolase activity	F	Catalysis of the reaction: D-fructose-6-phosphate = dihydroxyacetone + D-glyceraldehyde-3-phosphate.
97025	MPP7-DLG1-LIN7 complex	C	A heterotrimeric protein complex formed by the association of MMP7, DLG1 and either LIN7A or LIN7C; regulates the stability and localization of DLG1 to cell junctions.
97026	dendritic cell dendrite assembly	P	Formation of dendrites, branched cellular projections (or cytoplasmic extension) that are extended from the surface of a dendritic immune cell, and which enable the cell to sample luminal pathogens and increase the surface area for antigen presentation to T cells.
97027	ubiquitin-protein transferase activator activity	F	Increases the activity of a ubiquitin-protein transferase, an enzyme that catalyzes the covalent attachment of ubiquitin to lysine in a substrate protein.
97028	dendritic cell differentiation	P	The process in which a precursor cell type acquires the specialized features of a dendritic cell. A dendritic cell is a leukocyte of dendritic lineage specialized in the uptake, processing, and transport of antigens to lymph nodes for the purpose of stimulating an immune response via T cell activation.
97029	mature conventional dendritic cell differentiation	P	The process in which antigen-activated dendritic cells acquire the specialized features of a mature conventional dendritic cell. Mature conventional dendritic cells upregulate the surface expression of MHC molecules, chemokine receptors and adhesion molecules, and increase the number of dendrites (cytoplasmic protrusions) in preparation for migration to lymphoid organs where they present antigen to T cells.
97030	CENP-A containing nucleosome binding	F	Interacting selectively and non-covalently with a centromere-specific nucleosome, a form of nucleosome located only at the centromere, in which the histone H3 is replaced by the variant form CENP-A (sometimes known as CenH3).
97031	mitochondrial respiratory chain complex I biogenesis	P	The biogenesis of a mitochondrial respiratory chain complex I, a protein complex located in the mitochondrial inner membrane that forms part of the mitochondrial respiratory chain. Includes the synthesis of constituent proteins and their aggregation, arrangement and bonding together.
97032	mitochondrial respiratory chain complex II biogenesis	P	The biogenesis of a mitochondrial respiratory chain complex II, a protein complex located in the mitochondrial inner membrane that forms part of the mitochondrial respiratory chain. Includes the synthesis of constituent proteins and their aggregation, arrangement and bonding together.
97033	mitochondrial respiratory chain complex III biogenesis	P	The biogenesis of a mitochondrial respiratory chain complex III (also known as cytochrome bc(1) complex or ubiquinol-cytochrome c reductase), a protein complex located in the mitochondrial inner membrane that forms part of the mitochondrial respiratory chain. Includes the synthesis of constituent proteins and their aggregation, arrangement and bonding together.
97034	mitochondrial respiratory chain complex IV biogenesis	P	The biogenesis of a mitochondrial respiratory chain complex IV (also known as cytochrome c oxidase complex), a protein complex located in the mitochondrial inner membrane that forms part of the mitochondrial respiratory chain. Includes the synthesis of constituent proteins and their aggregation, arrangement and bonding together.
97035	regulation of membrane lipid distribution	P	Any process that modulates the proportions or spatial arrangement of lipids in a cellular membrane.
97036	regulation of plasma membrane sterol distribution	P	Any process that modulates the proportions or spatial arrangement of sterols in the plasma membrane.
97037	heme export	P	The directed movement of heme out of a cell or organelle.
97038	perinuclear endoplasmic reticulum	C	The portion of endoplasmic reticulum, the intracellular network of tubules and cisternae, that occurs near the nucleus. The lumen of the perinuclear endoplasmic reticulum is contiguous with the nuclear envelope lumen (also called perinuclear space), the region between the inner and outer nuclear membranes.
97039	protein linear polyubiquitination	P	A protein ubiquitination process in which a linear polymer of ubiquitin, formed by the amino-terminal methionine (M1) of one ubiquitin molecule and by the carboxy-terminal glycine (G76) of the next, is added to a protein.
97040	phthiocerol biosynthetic process	P	The chemical reactions and pathways resulting in the formation of phthiocerol, a lipid-based 1,3-glycol consisting of (3S,4R)-3-methoxy-4-methylnonacosane having (9R)- and (11S)-hydroxy substituents.
97041	phenolic phthiocerol biosynthetic process	P	The chemical reactions and pathways resulting in the formation of phenolic phthiocerol, a phthiocerol derivative having a 4-hydroxyphenyl substituent at the 29-position.
97042	extrinsic component of fungal-type vacuolar membrane	C	The component of a fungal-type vacuolar membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
97043	histone H3-K56 acetylation	P	The modification of histone H3 by the addition of an acetyl group to a lysine residue at position 56 of the histone.
97044	histone H3-K56 acetylation in response to DNA damage	P	The modification of histone H3 by the addition of an acetyl group to a lysine residue at position 56 of the histone as a result of the detection of DNA damage within a cell.
97045	phosphatidylserine exposure on blood platelet	P	A phospholipid scrambling process that results in the appearance of phosphatidylserine on the surface of activated blood platelets, and triggers the clotting system.
97046	replication fork progression beyond termination site	P	Regulation of DNA replication by a mechanism that allows a DNA replication fork to progress beyond a termination site, which is a region containing fork pausing elements that influence the progression and merging of DNA replication forks.
97047	DNA replication termination region	C	A chromosomal region that contains fork pausing elements influencing the progression and merging of DNA replication forks.
97048	dendritic cell apoptotic process	P	Any apoptotic process in a dendritic cell, a cell of hematopoietic origin, typically resident in particular tissues, specialized in the uptake, processing, and transport of antigens to lymph nodes for the purpose of stimulating an immune response via T cell activation.
97049	motor neuron apoptotic process	P	Any apoptotic process in a motor neuron, an efferent neuron that passes from the central nervous system or a ganglion toward or to a muscle and conducts an impulse that causes movement.
97050	type B pancreatic cell apoptotic process	P	Any apoptotic process in a type B pancreatic cell, a cell located towards center of the islets of Langerhans that secretes insulin.
97051	establishment of protein localization to endoplasmic reticulum membrane	P	The directed movement of a protein to a specific location in the endoplasmic reticulum membrane.
97052	L-kynurenine metabolic process	P	The chemical reactions and pathways involving L-kynurenine, the L-enantiomer of the amino acid kynurenine (3-(2-aminobenzoyl)-alanine).
97053	L-kynurenine catabolic process	P	The chemical reactions and pathways resulting in the breakdown of L-kynurenine, the L-enantiomer of the amino acid kynurenine (3-(2-aminobenzoyl)-alanine).
97054	L-glutamate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of L-glutamate, the L enantiomer anion of 2-aminopentanedioic acid.
97055	agmatine biosynthetic process	P	The chemical reactions and pathways resulting in the formation of agmatine ((4-aminobutyl)guanidine, NH2-CH2-CH2-CH2-CH2-NH-C(-NH2)(=NH)). Agmatine is the decarboxylation product of the amino acid arginine and is an intermediate in polyamine biosynthesis. It is synthesized in the brain, stored in synaptic vesicles, accumulated by uptake, released by membrane depolarization, and inactivated by agmatinase.
97056	selenocysteinyl-tRNA(Sec) biosynthetic process	P	The chemical reactions and pathways resulting in the formation of selenocysteinyl-tRNA(Sec). This process occurs through the following steps: a unique serine-tRNA with a UGA recognizing anticodon is first aminoacylated with serine; this is then phosphorylated by phosphoseryl-tRNA[Ser]Sec kinase; lastly, selenium is swapped for the phosphate on the serine.
97057	TRAF2-GSTP1 complex	C	A protein complex comprising tumor necrosis factor (TNF) receptor-associated factor 2 (TRAF2) and glutathione S-transferase pi 1 (GSTP1). This complex is thought to disrupt the TNF signaling cascade, thus down-regulating inflammatory responses.
97058	CRLF-CLCF1 complex	C	A heterodimeric protein complex that is composed of cardiotrophin-like cytokine factor 1 (product of the CLCF1 gene) and cytokine receptor-like factor 1 (product of the CRLF gene) and is secreted into the extracellular space. The CRLF-CLCF1 complex is a ligand for the ciliary neurotrophic factor (CNTF) receptor complex.
97059	CNTFR-CLCF1 complex	C	A protein complex that is composed of two soluble ciliary neurotrophic factor receptor alpha subunits (product of the CNTFR gene) and two molecules of cardiotrophin-like cytokine factor 1 (product of the CLCF1 gene). The complex is secreted into the extracellular space.
97060	synaptic membrane	C	A specialized area of membrane on either the presynaptic or the postsynaptic side of a synapse, the junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell.
97061	dendritic spine organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a dendritic spine. A dendritic spine is a specialized protrusion from a neuronal dendrite and is involved in synaptic transmission.
97062	dendritic spine maintenance	P	The organization process that preserves a dendritic spine in a stable functional or structural state. A dendritic spine is a specialized protrusion from a neuronal dendrite and is involved in synaptic transmission.
97063	cadmium ion sensor activity	F	Interacting selectively and non-covalently with and responding, e.g. by conformational change, to changes in the cellular level of cadmium (Cd++).
97064	ncRNA export from nucleus	P	The directed movement of a non-coding RNA transcript (ncRNA) from the nucleus to the cytoplasm.
97065	anterior head development	P	The process whose specific outcome is the progression of the anterior part of the head over time, from its formation to the mature structure.
97066	response to thyroid hormone	P	A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a thyroid hormone stimulus.
97067	cellular response to thyroid hormone stimulus	P	A change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a thyroid hormone stimulus.
97068	response to thyroxine	P	A change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a thyroxine stimulus.
97069	cellular response to thyroxine stimulus	P	A change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a thyroxine stimulus.
97070	ductus arteriosus closure	P	The morphogenesis process in which the ductus arteriosus changes to no longer permit blood flow after birth. The ductus arteriosus is the shunt between the aorta and the pulmonary artery which allows blood to bypass the fetus' lungs.
97071	interferon regulatory factor complex	C	A protein complex that consists of two interferon regulatory proteins (IRFs); may be homodimeric or heterodimeric. The activation of a latent closed conformation of IRF in the cytoplasm is triggered by phosphorylation of Ser/Thr residues in a C-terminal region. Phosphorylation stimulates the C-terminal autoinhibitory domain to attain a highly extended conformation triggering dimerization through extensive contacts to a second subunit.
97072	interferon regulatory factor 3 complex	C	An interferon regulatory factor complex that consists of a homodimer of interferon regulatory factor 3.
97073	interferon regulatory factor 5 complex	C	An interferon regulatory factor complex that consists of a homodimer of interferon regulatory factor 5.
97074	interferon regulatory factor 7 complex	C	An interferon regulatory factor complex that consists of a homodimer of interferon regulatory factor 7.
97075	interferon regulatory factor 3-interferon regulatory factor 7 complex	C	An interferon regulatory factor complex that consists of a heterodimer of interferon regulatory factor 3 and interferon regulatory factor 7.
97076	transforming growth factor beta activated kinase 1 complex	C	A protein complex that possesses protein kinase activity and activates the I-kappa B kinase complex (IKK) and mitogen-activated protein (MAP) kinases in response to TRAF6 signaling. It comprises the catalytic subunit TAK1 complexed to the regulatory subunits, termed TABs (TAK1-binding subunits).
97077	copper ion sensor activity	F	Interacting selectively and non-covalently with and responding, e.g. by conformational change, to changes in the cellular level of copper(I) (Cu+).
97078	FAL1-SGD1 complex	C	A protein complex involved in the 18S rRNA biogenesis. In S. cerevisiae this complex consists of Fal1p and Sgd1p and in humans this complex consists of NOM1 and eIF4AIII subunits.
97079	selenite:proton symporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: selenite(out) + H+(out) = selenite(in) + H+(in).
97080	plasma membrane selenite transport	P	The directed movement of inorganic selenite (HSeO3-1 at physiological pH) across a plasma membrane.
97081	vascular smooth muscle cell fate commitment	P	The commitment of cells to a vascular smooth muscle cell fate and their capacity to differentiate into vascular smooth muscle cells. A vascular smooth muscle cell is a non-striated, elongated, spindle-shaped cell found lining the blood vessels.
97082	vascular smooth muscle cell fate specification	P	The process in which a cell becomes capable of differentiating autonomously into a vascular smooth muscle cell in an environment that is neutral with respect to the developmental pathway. Upon specification, the cell fate can be reversed. A vascular smooth muscle cell is a non-striated, elongated, spindle-shaped cell found lining the blood vessels.
97083	vascular smooth muscle cell fate determination	P	The process in which a cell becomes capable of differentiating autonomously into a vascular smooth muscle cell regardless of its environment; upon determination, the cell fate cannot be reversed. A vascular smooth muscle cell is a non-striated, elongated, spindle-shaped cell found lining the blood vessels.
97084	vascular smooth muscle cell development	P	The process aimed at the progression of a vascular smooth muscle cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell. A vascular smooth muscle cell is a non-striated, elongated, spindle-shaped cell found lining the blood vessels.
97085	interferon regulatory factor 3-interferon regulatory factor 5 complex	C	An interferon regulatory factor complex that consists of a heterodimer of interferon regulatory factor 3 and interferon regulatory factor 5.
97086	amniotic stem cell differentiation	P	The process whereby a relatively unspecialized cell acquires specialized features of an amniotic stem cell. An amniotic stem cell is a mesenchymal stem cell extracted from amniotic fluid. Amniotic stem cells are able to differentiate into various tissue types such as skin, cartilage, cardiac tissue, nerves, muscle, and bone.
97087	interleukin-17A production	P	The appearance of interleukin-17A due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
97088	interleukin-17F production	P	The appearance of interleukin-17F due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
97089	methyl-branched fatty acid metabolic process	P	The chemical reactions and pathways involving methyl-branched fatty acids, aliphatic monocarboxylic acids with methyl branches on the main chain.
97090	presynaptic membrane organization	P	A process which results in the assembly, arrangement of constituent parts, or disassembly of a presynaptic membrane, including any proteins associated with the membrane, but excluding other cellular components. A presynaptic membrane is a specialized area of membrane of the axon terminal that faces the plasma membrane of the neuron or muscle fiber with which the axon terminal establishes a synaptic junction.
97091	synaptic vesicle clustering	P	The process that results in grouping synaptic vesicles, prior to release, at a specialized patch of the presynaptic membrane referred to as the active zone.
97092	polyacyltrehalose metabolic process	P	The chemical reactions and pathways involving polyacyltrehalose, a pentaacylated, trehalose-based glycolipid.
97093	polyacyltrehalose biosynthetic process	P	The chemical reactions and pathways resulting in the formation of polyacyltrehalose, a pentaacylated, trehalose-based glycolipid.
97094	craniofacial suture morphogenesis	P	The process in which any suture between cranial and/or facial bones is generated and organized.
97095	frontonasal suture morphogenesis	P	The process in which the frontonasal suture, between frontal and nasal bones, is generated and organized.
97096	facial suture morphogenesis	P	The process in which any suture between facial bones is generated and organized.
97097	nasal suture morphogenesis	P	The process in which the nasal suture is generated and organized.
97098	DNA/RNA hybrid annealing activity	F	Facilitates the base-pairing of single-stranded RNA to double-stranded DNA resulting in the formation of R-loops.
97099	structural constituent of albumen	F	The action of a molecule that contributes to the structural integrity of albumen (also called egg white). Albumen is the clear liquid contained within an egg and consists of water and proteins, among which are ovomucin and ovomucoid. It protects the egg yolk and provides additional nutrition for the growth of the embryo.
97100	supercoiled DNA binding	F	Interacting selectively and non-covalently with supercoiled DNA. For example, during replication and transcription, template DNA is negatively supercoiled in the receding downstream DNA and positively supercoiled in the approaching downstream DNA.
97101	blood vessel endothelial cell fate specification	P	The process involved in the specification of identity of a blood vessel endothelial cell. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment. A blood vessel endothelial cell is an endothelial cell of the vascular tree, which includes blood vessels and lymphatic vessels.
97102	endothelial tip cell fate specification	P	The process involved in the specification of identity of an endothelial tip cell. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment. An endothelial tip cell is a specialized endothelial cell localized to the leading edge of an angiogenic sprout that senses extracellular signals and guides the directed growth of blood vessels.
97103	endothelial stalk cell fate specification	P	The process involved in the specification of identity of an endothelial stalk cell. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment. An endothelial stalk cell is a specialized endothelial cell which follows behind the tip cell of an angiogenic sprout.
97104	postsynaptic membrane assembly	P	The aggregation, arrangement and bonding together of a set of components to form a postsynaptic membrane, a specialized area of membrane facing the presynaptic membrane on the tip of the nerve ending and separated from it by a minute cleft (the synaptic cleft).
97105	presynaptic membrane assembly	P	The aggregation, arrangement and bonding together of a set of components to form a presynaptic membrane, including any proteins associated with the membrane, but excluding other cellular components. A presynaptic membrane is a specialized area of membrane of the axon terminal that faces the plasma membrane of the neuron or muscle fiber with which the axon terminal establishes a synaptic junction.
97106	postsynaptic density organization	P	A process that results in the assembly, arrangement of constituent parts, or disassembly of a postsynaptic density, a region that lies adjacent to the cytoplasmic face of the postsynaptic membrane at excitatory synapse.
97107	postsynaptic density assembly	P	The aggregation, arrangement and bonding together of a set of components to form a postsynaptic density, a region that lies adjacent to the cytoplasmic face of the postsynaptic membrane at excitatory synapse.
97108	hedgehog family protein binding	F	Interacting selectively and non-covalently with a member of the hedgehog protein family, signaling proteins involved in development.
97109	neuroligin family protein binding	F	Interacting selectively and non-covalently with a member of the neuroligin protein family, neuronal cell surface proteins that mediate synapse formation.
97110	scaffold protein binding	F	Interacting selectively and non-covalently with a scaffold protein. Scaffold proteins are crucial regulators of many key signaling pathways. Although not strictly defined in function, they are known to interact and/or bind with multiple members of a signaling pathway, tethering them into complexes.
97111	endoplasmic reticulum-Golgi intermediate compartment organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the endoplasmic reticulum (ER)-Golgi intermediate compartment.
97112	gamma-aminobutyric acid receptor clustering	P	The receptor clustering process in which gamma-aminobutyric acid (GABA) receptors are localized to distinct domains in the cell membrane.
97113	AMPA glutamate receptor clustering	P	The glutamate receptor clustering process in which alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptors are localized to distinct domains in the cell membrane.
97114	NMDA glutamate receptor clustering	P	The receptor clustering process in which N-methyl-D-aspartate (NMDA) receptors are localized to distinct domains in the cell membrane.
97115	neurexin clustering involved in presynaptic membrane assembly	P	The receptor clustering process involved in assembly of the presynaptic membrane in which neurexins are localized to distinct domains in the cell membrane. Neurexins are synaptic cell surface proteins which act as cell recognition molecules at nerve terminals.
97116	gephyrin clustering involved in postsynaptic density assembly	P	The clustering process in which gephyrin molecules are localized to distinct domains in the postsynaptic density as part of postsynaptic density assembly. Gephyrin is a component of the postsynaptic protein network of inhibitory synapses.
97117	guanylate kinase-associated protein clustering	P	The clustering process in which guanylate kinase-associated proteins (GKAPs) are localized to distinct domains in the cell membrane. GKAP facilitates assembly of the post synaptic density of neurons.
97118	neuroligin clustering involved in postsynaptic membrane assembly	P	The receptor clustering process involved in assembly of the postsynaptic membrane in which neuroligins are localized to distinct domains in the cell membrane. Neuroligins are neuronal cell surface proteins on the postsynaptic membrane that mediate synapse formation between neurons.
97119	postsynaptic density protein 95 clustering	P	The clustering process in which postsynaptic density protein 95 (PSD-95) molecules are localized to distinct domains in the cell membrane. PSD-95 is mostly located in the post synaptic density of neurons, and is involved in anchoring synaptic proteins.
97120	receptor localization to synapse	P	Any process in which a receptor is transported to, and/or maintained at the synapse, the junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell.
97121	cyclin A1-CDK1 complex	C	A protein complex consisting of cyclin A1 and cyclin-dependent kinase 1 (CDK1). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner.
97122	cyclin A2-CDK1 complex	C	A protein complex consisting of cyclin A2 and cyclin-dependent kinase 1 (CDK1). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner.
97123	cyclin A1-CDK2 complex	C	A protein complex consisting of cyclin A1 and cyclin-dependent kinase 2 (CDK2). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner.
97124	cyclin A2-CDK2 complex	C	A protein complex consisting of cyclin A2 and cyclin-dependent kinase 2 (CDK2). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner.
97125	cyclin B1-CDK1 complex	C	A protein complex consisting of cyclin B1 and cyclin-dependent kinase 1 (CDK1). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner.
97126	cyclin B2-CDK1 complex	C	A protein complex consisting of cyclin B2 and cyclin-dependent kinase 1 (CDK1). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner.
97127	cyclin B3-CDK2 complex	C	A protein complex consisting of cyclin B3 and cyclin-dependent kinase 2 (CDK2). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner.
97128	cyclin D1-CDK4 complex	C	A protein complex consisting of cyclin D1 and cyclin-dependent kinase 4 (CDK4). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner.
97129	cyclin D2-CDK4 complex	C	A protein complex consisting of cyclin D2 and cyclin-dependent kinase 4 (CDK4). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner.
97130	cyclin D3-CDK4 complex	C	A protein complex consisting of cyclin D3 and cyclin-dependent kinase 4 (CDK4). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner.
97131	cyclin D1-CDK6 complex	C	A protein complex consisting of cyclin D1 and cyclin-dependent kinase 6 (CDK6). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner.
97132	cyclin D2-CDK6 complex	C	A protein complex consisting of cyclin D2 and cyclin-dependent kinase 6 (CDK6). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner.
97133	cyclin D3-CDK6 complex	C	A protein complex consisting of cyclin D3 and cyclin-dependent kinase 6 (CDK6). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner.
97134	cyclin E1-CDK2 complex	C	A protein complex consisting of cyclin E1 and cyclin-dependent kinase 2 (CDK2). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner.
97135	cyclin E2-CDK2 complex	C	A protein complex consisting of cyclin E2 and cyclin-dependent kinase 2 (CDK2). Cyclins are characterized by periodicity in protein abundance throughout the cell cycle. Cyclin-dependent kinases represent a family of serine/threonine protein kinases that become active upon binding to a cyclin regulatory partner.
97136	Bcl-2 family protein complex	C	A protein complex that consists of members of the Bcl-2 family of anti- and proapoptotic regulators. Bcl-2 proteins respond to cues from various forms of intracellular stress, such as DNA damage or cytokine deprivation, and interact with opposing family members to determine whether or not the caspase proteolytic cascade should be unleashed.
97137	BAD-BCL-xl complex	C	A heterodimeric protein complex consisting of BAD and BCL-xl, members of the Bcl-2 family of anti- and proapoptotic regulators.
97138	BAD-BCL-2 complex	C	A heterodimeric protein complex consisting of BAD and BCL-2, members of the Bcl-2 family of anti- and proapoptotic regulators.
97139	BID-BCL-2 complex	C	A heterodimeric protein complex consisting of BID and BCL-2, members of the Bcl-2 family of anti- and proapoptotic regulators.
97140	BIM-BCL-xl complex	C	A heterodimeric protein complex consisting of BIM and BCL-xl, members of the Bcl-2 family of anti- and proapoptotic regulators.
97141	BIM-BCL-2 complex	C	A heterodimeric protein complex consisting of BIM and BCL-2, members of the Bcl-2 family of anti- and proapoptotic regulators.
97142	PUMA-BCL-2 complex	C	A heterodimeric protein complex consisting of PUMA and BCL-2, members of the Bcl-2 family of anti- and proapoptotic regulators.
97143	PUMA-BCL-xl complex	C	A heterodimeric protein complex consisting of PUMA and BCL-xl, members of the Bcl-2 family of anti- and proapoptotic regulators.
97144	BAX complex	C	An oligomeric protein complex consisting of BAX, a member of the Bcl-2 family of anti- and proapoptotic regulators.
97145	BAK complex	C	An oligomeric protein complex consisting of BAK, a member of the Bcl-2 family of anti- and proapoptotic regulators.
97146	NOXA-BCL-xl complex	C	A heterodimeric protein complex consisting of NOXA and BCL-xl, members of the Bcl-2 family of anti- and proapoptotic regulators.
97147	NOXA-BCL-2 complex	C	A heterodimeric protein complex consisting of NOXA and BCL-2, members of the Bcl-2 family of anti- and proapoptotic regulators.
97148	BCL-2 complex	C	A homodimeric protein complex consisting of BCL-2, a member of the Bcl-2 family of anti- and proapoptotic regulators.
97149	centralspindlin complex	C	A heterotetrameric protein complex playing a key role in the formation of the central spindle in mitosis. Made up of two molecules each of a mitotic kinesin (ZEN-4 in Caenorhabditis elegans or MKLP1 in mammals) and of two molecules each of a GTPase activating protein (GAP) factor (CYK-4 in Caenorhabditis elegans or MgcRacGAP in mammals).
97150	neuronal stem cell population maintenance	P	Any process in by an organism or tissue maintains a population of neuronal stem cells.
97151	positive regulation of inhibitory postsynaptic potential	P	Any process that activates or increases the frequency, rate or extent of inhibitory postsynaptic potential (IPSP). IPSP is a temporary decrease in postsynaptic membrane potential due to the flow of negatively charged ions into the postsynaptic cell. The flow of ions that causes an IPSP is an inhibitory postsynaptic current (IPSC) and makes it more difficult for the neuron to fire an action potential.
97152	mesenchymal cell apoptotic process	P	Any apoptotic process in a mesenchymal cell. A mesenchymal cell is a loosely associated cell that is part of the connective tissue in an organism. Mesenchymal cells give rise to more mature connective tissue cell types.
97153	cysteine-type endopeptidase activity involved in apoptotic process	F	Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile, and contributing to the apoptotic process.
97154	GABAergic neuron differentiation	P	The process in which a neuroblast acquires the specialized structural and functional features of a GABAergic neuron.
97155	fasciculation of sensory neuron axon	P	The collection of sensory neuron axons into a bundle of rods, known as a fascicle.
97156	fasciculation of motor neuron axon	P	The collection of motor neuron axons into a bundle of rods, known as a fascicle.
97157	pre-mRNA intronic binding	F	Interacting selectively and non-covalently with an intronic sequence of a pre-messenger RNA (pre-mRNA).
97158	pre-mRNA intronic pyrimidine-rich binding	F	Interacting selectively and non-covalently with a pyrimidine-rich (CU-rich) intronic sequence of a pre-messenger RNA (pre-mRNA).
97159	organic cyclic compound binding	F	Interacting selectively and non-covalently with an organic cyclic compound, any molecular entity that contains carbon arranged in a cyclic molecular structure.
97160	polychlorinated biphenyl binding	F	Interacting selectively and non-covalently with a polychlorinated biphenyl (PCB), a biphenyl compound containing between 2 and 10 chlorine atoms attached to the two benzene rings.
97161	DH domain binding	F	Interacting selectively and non-covalently with a DH (Dbl homology) domain of a protein. The DH domain contains three structurally conserved regions separated by more variable regions. It is composed of 11 alpha helices that are folded into a flattened, elongated alpha-helix bundle in which two of the three conserved regions, conserved region 1 (CR1) and conserved region 3 (CR3), are exposed near the centre of one surface. CR1 and CR3, together with a part of alpha-6 and the DH/PH (pleckstrin homology) junction site, constitute the Rho GTPase interacting pocket.
97162	MADS box domain binding	F	Interacting selectively and non-covalently with a MADS box domain, a protein domain that encodes the DNA-binding MADS domain. The MADS domain binds to DNA sequences of high similarity to the motif CC[A/T]6GG termed the CArG-box. MADS-domain proteins are generally transcription factors. The length of the MADS-box is in the range of 168 to 180 base pairs.
97163	sulfur carrier activity	F	Enables the directed movement of sulfur into, out of or within a cell, or between cells.
97164	ammonium ion metabolic process	P	The chemical reactions and pathways involving the ammonium ion.
97165	nuclear stress granule	C	A dense aggregation in the nucleus composed of proteins and RNAs that appear when the cell is under stress.
97166	lens epithelial cell proliferation	P	The multiplication or reproduction of lens epithelial cells, resulting in the expansion of a cell population. Lens epithelial cells make up the lens epithelium, which is located in the anterior portion of the lens between the lens capsule and the lens fibers and is a simple cuboidal epithelium. The epithelial cells of the lens regulate most of the homeostatic functions of the lens such as osmolarity and liquid volume. The lens epithelial cells also serve as the progenitors for new lens fibers. The lens epithelium constantly lays down fibers in the embryo, fetus, infant, and adult, and continues to lay down fibers for lifelong growth.
97167	circadian regulation of translation	P	Any process that modulates the frequency, rate or extent of mRNA translation with a regularity of approximately 24 hours.
97168	mesenchymal stem cell proliferation	P	The multiplication or reproduction of mesenchymal stem cells, resulting in the expansion of a stem cell population. A mesenchymal stem cell, or MSC, is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized mesenchymal cells.
97169	AIM2 inflammasome complex	C	A protein complex that consists of AIM2, ASC, and caspase-1. AIM2 is a member of the HN-200 protein family that appears to be the sensor of cytosolic double-stranded DNA.
97170	ADP-L-glycero-beta-D-manno-heptose metabolic process	P	The chemical reactions and pathways involving ADP-L-glycero-beta-D-manno-heptose, an ADP-L-glycero-D-manno-heptose having beta-configuration at the anomeric centre of the heptose. ADP-L-glycero-beta-D-manno-heptose (also called ADP-L-beta-D-heptose or ADP-L-glycero-D-manno-heptose) is a nucleotide-sugar precursor of the inner core lipopolysaccharide (LPS) from D-glycero-beta-D-manno-heptose 7-phosphate.
97171	ADP-L-glycero-beta-D-manno-heptose biosynthetic process	P	The chemical reactions and pathways resulting in the formation of ADP-L-glycero-beta-D-manno-heptose, an ADP-L-glycero-D-manno-heptose having beta-configuration at the anomeric centre of the heptose. ADP-L-glycero-beta-D-manno-heptose (also called ADP-L-beta-D-heptose or ADP-L-glycero-D-manno-heptose) is a nucleotide-sugar precursor of the inner core lipopolysaccharide (LPS) from D-glycero-beta-D-manno-heptose 7-phosphate.
97172	N-acetylmuramic acid metabolic process	P	The chemical reactions and pathways involving N-acetylmuramic acid (MurNAc), a monosaccharide derivative of N-acetylglucosamine.
97173	N-acetylmuramic acid catabolic process	P	The chemical reactions and pathways resulting in the breakdown of N-acetylmuramic acid (MurNAc), a monosaccharide derivative of N-acetylglucosamine.
97174	1,6-anhydro-N-acetyl-beta-muramic acid metabolic process	P	The chemical reactions and pathways involving 1,6-anhydro-N-acetyl-beta-muramic acid, the 1,6-anhydro-derivative of N-acetyl-beta-muramic acid.
97175	1,6-anhydro-N-acetyl-beta-muramic acid catabolic process	P	The chemical reactions and pathways resulting in the breakdown of 1,6-anhydro-N-acetylmuramic acid, the 1,6-anhydro-derivative of N-acetyl-beta-muramic acid.
97176	epoxide metabolic process	P	The chemical reactions and pathways involving epoxides, compounds in which an oxygen atom is directly attached to two adjacent or non-adjacent carbon atoms of a carbon chain or ring system; thus cyclic ethers.
97177	mitochondrial ribosome binding	F	Interacting selectively and non-covalently with any part of a mitochondrial ribosome, a ribosome found in the mitochondrion of a eukaryotic cell.
97178	ruffle assembly	P	The aggregation, arrangement and bonding together of a set of components to form a ruffle, a projection at the leading edge of a crawling cell; the protrusions are supported by a microfilament meshwork. The formation of ruffles (also called membrane ruffling) is thought to be controlled by a group of enzymes known as Rho GTPases, specifically RhoA, Rac1 and cdc42.
97179	protease inhibitor complex	C	A heterodimeric protein complex that contains a protease inhibitor and a protease; formation of the complex inhibits protease activity.
97180	serine protease inhibitor complex	C	A heterodimeric protein complex that contains a serine protease inhibitor and a protease; formation of the complex inhibits serine protease activity.
97181	protein C inhibitor-coagulation factor V complex	C	A heterodimeric protein complex that contains protein C inhibitor (SERPINA5) and coagulation factor V (F5); formation of the complex inhibits the serine protease activity of coagulation factor V.
97182	protein C inhibitor-coagulation factor Xa complex	C	A heterodimeric protein complex that contains protein C inhibitor (SERPINA5) and coagulation factor Xa (F10); formation of the complex inhibits the serine protease activity of coagulation factor Xa.
97183	protein C inhibitor-coagulation factor XI complex	C	A heterodimeric protein complex that contains protein C inhibitor (SERPINA5) and coagulation factor XI (F11); formation of the complex inhibits the serine protease activity of coagulation factor XI.
97184	response to azide	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an azide stimulus.
97185	cellular response to azide	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an azide stimulus.
97186	amelogenesis	P	The process whose specific outcome is the formation of tooth enamel, occurring in two stages: secretory stage and maturation stage.
97187	dentinogenesis	P	The process whose specific outcome is the formation of dentin, the mineralized tissue that constitutes the major bulk of teeth. Dentin may be one of three types: primary dentin, secondary dentin, and tertiary dentin.
97188	dentin mineralization	P	The process in which calcium salts are deposited into the calcareous tooth structure known as dentin.
97189	apoptotic body	C	A vesicle containing parts of a dying cell. Apoptotic bodies can be formed during the execution phase of the apoptotic process, when the cell's cytoskeleton breaks up and causes the membrane to bulge outward. These bulges may separate from the cell, taking a portion of cytoplasm with them, to become apoptotic bodies. These are then engulfed by phagocytic cells, and their components recycled. Apoptotic bodies may range in size from 0.8 to 5um.
97190	apoptotic signaling pathway	P	A series of molecular signals which triggers the apoptotic death of a cell. The pathway starts with reception of a signal, and ends when the execution phase of apoptosis is triggered.
97191	extrinsic apoptotic signaling pathway	P	A series of molecular signals in which a signal is conveyed from the cell surface to trigger the apoptotic death of a cell. The pathway starts with either a ligand binding to a cell surface receptor, or a ligand being withdrawn from a cell surface receptor (e.g. in the case of signaling by dependence receptors), and ends when the execution phase of apoptosis is triggered.
97192	extrinsic apoptotic signaling pathway in absence of ligand	P	A series of molecular signals in which a signal is conveyed from the cell surface to trigger the apoptotic death of a cell. The pathway starts with withdrawal of a ligand from a cell surface receptor, and ends when the execution phase of apoptosis is triggered.
97193	intrinsic apoptotic signaling pathway	P	A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway starts with reception of an intracellular signal (e.g. DNA damage, endoplasmic reticulum stress, oxidative stress etc.), and ends when the execution phase of apoptosis is triggered. The intrinsic apoptotic signaling pathway is crucially regulated by permeabilization of the mitochondrial outer membrane (MOMP).
97194	execution phase of apoptosis	P	A stage of the apoptotic process that starts with the controlled breakdown of the cell through the action of effector caspases or other effector molecules (e.g. cathepsins, calpains etc.). Key steps of the execution phase are rounding-up of the cell, retraction of pseudopodes, reduction of cellular volume (pyknosis), chromatin condensation, nuclear fragmentation (karyorrhexis), plasma membrane blebbing and fragmentation of the cell into apoptotic bodies. When the execution phase is completed, the cell has died.
97195	pilomotor reflex	P	The reflex process in which the arrectores pilorum (hair follicle) muscles contract and cause the hair to stand erect.
97196	Shu complex	C	A protein complex involved in error-free DNA post-replication repair (PRR). In Saccharomyces cerevisiae the complex contains Csm2p, Psy3p, Shu1p, and Shu2p.
97197	tetraspanin-enriched microdomain	C	A pre-organized unit composed either of adhesion molecules (mainly integrins and members of the Ig superfamily), signaling receptors and/or enzyme-enriched plasma membrane domains that compartmentalizes cellular processes. Tetraspanin-enriched microdomains might be specially suited for the regulation of avidity of adhesion receptors and the compartmentalization of enzymatic activities.
97198	histone H3-K36 trimethylation	P	The modification of histone H3 by addition of three methyl groups to lysine at position 36 of the histone.
97199	cysteine-type endopeptidase activity involved in apoptotic signaling pathway	F	Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile, and contributing to the apoptotic signaling pathway.
97200	cysteine-type endopeptidase activity involved in execution phase of apoptosis	F	Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile, and contributing to the execution phase of apoptosis.
97201	negative regulation of transcription from RNA polymerase II promoter in response to stress	P	Any process that decreases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).
97202	activation of cysteine-type endopeptidase activity	P	Any process that initiates the activity of the inactive enzyme cysteine-type endopeptidase.
97203	phagocytic cup lip	C	The tip or margin of the progressing circular lamella that engulfs a particle during phagocytosis. When the two lips of the cup fuse it is converted into a phagosome.
97204	phagocytic cup base	C	The older part of the phagocytic cup where the actin cytoskeleton disassembles, allowing early incoming and outgoing vesicular trafficking.
97205	renal filtration	P	A renal system process in which fluid circulating through the body is filtered through a barrier system.
97206	nephrocyte filtration	P	The process by which hemolymph is filtered based on size and charge through a nephrocyte filtration barrier formed by the basement membrane and nephrocyte diaphragm.
97207	bud dormancy process	P	A dormancy process in which dormancy (sometimes called a dormant state) is induced, maintained or broken in a bud. Bud dormancy is a suspension of most physiological activity and growth that can be reactivated. It may be a response to environmental conditions such as seasonality or extreme heat, drought, or cold. The exit from bud dormancy is marked by the resumed growth of the bud.
97208	alveolar lamellar body	C	A specialized secretory organelle found in type II pneumocytes and involved in the synthesis, secretion, and reutilization of pulmonary surfactant.
97209	epidermal lamellar body	C	A specialized secretory organelle found in keratinocytes and involved in the formation of an impermeable, lipid-containing membrane that serves as a water barrier and is required for correct skin barrier function.
97210	response to gonadotropin-releasing hormone	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gonadotropin-releasing hormone stimulus. Gonadotropin-releasing hormone (GnRH) is a peptide hormone responsible for the release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) from the anterior pituitary. GnRH is synthesized and released by the hypothalamus.
97211	cellular response to gonadotropin-releasing hormone	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gonadotropin-releasing hormone stimulus. Gonadotropin-releasing hormone (GnRH) is a peptide hormone responsible for the release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) from the anterior pituitary. GnRH is synthesized and released by the hypothalamus.
97212	lysosomal membrane organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lysosomal membrane. A lysosomal membrane is the lipid bilayer surrounding the lysosome and separating its contents from the cell cytoplasm.
97213	regulation of lysosomal membrane permeability	P	Any process that modulates the frequency, rate or extent of the passage or uptake of molecules by the lysosomal membrane.
97214	positive regulation of lysosomal membrane permeability	P	Any process that increases the frequency, rate or extent of the passage or uptake of molecules by the lysosomal membrane.
97215	negative regulation of lysosomal membrane permeability	P	Any process that decreases the frequency, rate or extent of the passage or uptake of molecules by the lysosomal membrane.
97216	guanosine tetraphosphate binding	F	Interacting selectively and non-covalently with guanosine tetraphosphate (5'-ppGpp-3'), a guanosine bisphosphate having diphosphate groups at both the 3' and 5'-positions.
97217	sieve area	C	A pit-like area in the cell wall of a sieve element; contains pores lined with callose and occupied by strands of protoplasmic material that interconnect the protoplasts of contiguous sieve elements.
97218	sieve plate	C	A part of the cell wall of a sieve tube member that bears one or more highly specialized sieve areas.
97219	compound sieve plate	C	A sieve plate that contains several specialized sieve areas in either a scalariform or reticulate arrangement.
97220	simple sieve plate	C	A sieve plate that contains a single specialized sieve area.
97221	M/G1 phase-specific MADS box-forkhead transcription factor complex	C	A protein complex that contains a MADS-box protein and two forkhead domain proteins, and binds to and regulates transcription from promoters of genes transcribed during the M/G1 transition of the cell cycle. In Schizosaccharomyces pombe, the complex contains the MADS-box protein Mbx1 and two forkhead proteins, Sep1 and Fkh2.
97222	mitochondrial mRNA polyadenylation	P	The enzymatic addition of a sequence of 40-60 adenylyl residues at the 3' end of a eukaryotic mitochondrial mRNA primary transcript. Mitochondria contain both stabilizing and destabilizing poly(A) tails.
97223	sperm part	C	Any constituent part of a sperm, a mature male germ cell that develops from a spermatid.
97224	sperm connecting piece	C	The segment of the sperm flagellum that attaches to the implantation fossa of the nucleus in the sperm head; from the remnant of the centriole at this point, the axoneme extends throughout the length of the flagellum.
97225	sperm midpiece	C	The highly organized segment of the sperm flagellum which begins at the connecting piece and is characterized by the presence of 9 outer dense fibers (ODFs) that lie outside each of the 9 outer axonemal microtubule doublets and by a sheath of mitochondria that encloses the ODFs and the axoneme; the midpiece terminates about one-fourth of the way down the sperm flagellum at the annulus, which marks the beginning of the principal piece.
97226	sperm mitochondrial sheath	C	The tightly packed helical sheath of ATP-producing mitochondria restricted to the midpiece of the sperm flagellum.
97227	sperm annulus	C	The ring-like, filamentous structure located at the distal end of the midpiece of the sperm flagellum; the annulus is thought to form a diffusion barrier between the midpiece and the principal piece and serve as a stabilizing structure for tail rigidity.
97228	sperm principal piece	C	The segment of the sperm flagellum where the mitochondrial sheath ends, and the outer dense fibers (ODFs) associated with outer axonemal doublets 3 and 8 are replaced by the 2 longitudinal columns of the fibrous sheath (FS) which run the length of the principal piece and are stabilized by circumferential ribs. The principal piece makes up ~2/3 of the length of the sperm flagellum and is defined by the presence of the FS and of only 7 (rather than 9) ODFs which taper and then terminate near the distal end of the principal piece.
97229	sperm end piece	C	The short tip of the sperm flagellum, adjacent to the sperm principal piece and furthest from the sperm head, which contains only the axoneme surrounded by the plasma membrane.
97230	cell motility in response to potassium ion	P	Any process involved in the controlled self-propelled movement of a cell that results in translocation of the cell from one place to another as a result of a potassium ion stimulus.
97231	cell motility in response to calcium ion	P	Any process involved in the controlled self-propelled movement of a cell that results in translocation of the cell from one place to another as a result of a calcium ion stimulus.
97232	lamellar body membrane	C	The lipid bilayer surrounding a lamellar body. A lamellar body is a membrane-bounded organelle, specialized for the storage and secretion of various substances (surfactant phospholipids, glycoproteins and acid phosphates) which are arranged in the form of tightly packed, concentric, membrane sheets or lamellae. Has some similar properties to, but is distinct from, a lysosome.
97233	alveolar lamellar body membrane	C	The lipid bilayer surrounding an alveolar lamellar body, a specialized secretory organelle found in type II pneumocytes and involved in the synthesis, secretion, and reutilization of pulmonary surfactant.
97234	epidermal lamellar body membrane	C	The lipid bilayer surrounding an epidermal lamellar body, a specialized secretory organelle found in keratinocytes and involved in the formation of an impermeable, lipid-containing membrane that serves as a water barrier and is required for correct skin barrier function.
97235	positive regulation of fatty acid beta-oxidation by positive regulation of transcription from RNA polymerase II promoter	P	Any process that activates or increases the frequency, rate or extent of fatty acid beta-oxidation by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter.
97236	positive regulation of transcription from RNA polymerase II promoter in response to zinc ion starvation	P	Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of deprivation of zinc ions.
97237	cellular response to toxic substance	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a toxic stimulus.
97238	cellular response to methylglyoxal	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methylglyoxal stimulus. Methylglyoxal is a 2-oxoaldehyde derived from propanal.
97239	positive regulation of transcription from RNA polymerase II promoter in response to methylglyoxal	P	Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter in response to a methylglyoxal stimulus.
97240	chromosome attachment to the nuclear envelope	P	The process in which chromatin is anchored to the nuclear envelope.
97241	hematopoietic stem cell migration to bone marrow	P	The orderly movement of a hematopoietic stem cell into the bone marrow, and its subsequent positioning within defined functional compartments in that microenvironment. A hematopoietic stem cell is a cell from which all cells of the lymphoid and myeloid lineages develop, including blood cells and cells of the immune system.
97242	beta-amyloid clearance	P	The process in which beta-amyloid is removed from the brain via receptors.
97243	flavonoid binding	F	Interacting selectively and non-covalently with a flavonoid, a compound containing two or more aromatic rings, each bearing at least one aromatic hydroxyl and connected with a carbon bridge.
97244	flavonol binding	F	Interacting selectively and non-covalently with a flavonol, a flavonoid that contains a 3-hydroxy-2-phenylchromen-4-one backbone.
97245	flavanol binding	F	Interacting selectively and non-covalently with a flavanol.
97246	catechin binding	F	Interacting selectively and non-covalently with a catechin, a polyphenolic antioxidant plant metabolite with a flavonoid or flavan-3-ol structure.
97247	epigallocatechin 3-gallate binding	F	Interacting selectively and non-covalently with epigallocatechin 3-gallate, a compound that is a gallic acid ester of a catechin.
97248	maintenance of protein location in cell cortex of cell tip	P	A process in which a protein or protein complex is maintained in a specific location in the cell cortex of a cell tip, and is prevented from moving elsewhere. The cell cortex of a cell tip is the region directly beneath the plasma membrane at either end of the longest axis of a cylindrical or elongated cell.
97249	mitochondrial respiratory chain supercomplex	C	A set of respiratory enzyme complexes of the mitochondrial inner membrane (including, for example, Complex II, Complex III, Complex IV, or F1-F0 ATPase) arranged to form a large supercomplex.
97250	mitochondrial respiratory chain supercomplex assembly	P	The aggregation, arrangement and bonding together of a set of respiratory enzyme complexes of the mitochondrial inner membrane (including, for example, Complex II, Complex III, Complex IV, or F1-F0 ATPase) to form a large supercomplex.
97251	leukotriene B4 biosynthetic process	P	The chemical reactions and pathways resulting in the formation of leukotriene B4, a leukotriene composed of (6Z,8E,10E,14Z)-eicosatetraenoic acid having (5S)- and (12R)-hydroxy substituents.
97252	oligodendrocyte apoptotic process	P	Any apoptotic process in an oligodendrocyte. Oligodendrocytes belong to a class of large neuroglial (macroglial) cells in the central nervous system, where they form the insulating myelin sheath of axons.
97253	beta-hydroxybutyrate transmembrane transporter activity	F	Enables the transfer of beta-hydroxybutyrate from one side of the membrane to the other. Beta-hydroxybutyrate is the conjugate base of (R)-3-hydroxybutyric acid.
97254	renal tubular secretion	P	Secretion of substances from peritubular capillaries into the renal tubules to be incorporated subsequently into the urine. Substances that are secreted include organic anions, ammonia, potassium and drugs.
97255	R2TP complex	C	A highly conserved protein complex comprised of two ATP-dependent DNA helicases (Rvb1p and Rvb2p in yeast, Pontin52 and Reptin52 in humans), Pih1p in yeast or PIH1D1 in humans, and Tah1 in yeast or RPAP3 in humans. The complex associates with Hsp90 and is thought to have a role in assembly of large protein or protein/nucleic acid complexes. In this role it is involved in multiple processes such as box C/D snoRNP biogenesis, phosphatidylinositol-3 kinase-related protein kinase (PIKK) signaling, RNA polymerase II assembly, and others.
97256	phenyllactate dehydrogenase activity	F	Catalysis of the oxidation of phenyllactate to produce phenylpyruvate.
97257	leukotriene B4 12-hydroxy dehydrogenase activity	F	Catalysis of the reaction: leukotriene B4 + NADP(+) = 12-oxo-leukotriene B4 + NADPH + H(+).
97258	20-hydroxy-leukotriene B4 omega oxidase activity	F	Catalysis of the reaction: 20-hydroxy-leukotriene B4 + O2 + NADPH + H(+) = 20-aldehyde-leukotriene B4 + 2H2O + NADP(+).
97259	20-aldehyde-leukotriene B4 20-monooxygenase activity	F	Catalysis of the reaction: 20-aldehyde-leukotriene B4 + O2 + NADPH + H(+) = 20-carboxy-leukotriene B4 + H2O + NADP(+).
97260	eoxin A4 synthase activity	F	Catalysis of the reaction: leukotriene A4 = eoxin A4.
97261	eoxin C4 synthase activity	F	Catalysis of the reaction: eoxin A4 + glutathione = eoxin C4.
97262	eoxin D4 synthase activity	F	Catalysis of the reaction: eoxin C4 = eoxin D4 + 5-L-glutamyl amino acid.
97263	eoxin E4 synthase activity	F	Catalysis of the reaction: eoxin D4 + H20 = eoxin E4 + glycine.
97264	self proteolysis	P	The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their own peptide bonds.
97265	5(S)-hydroxyeicosatetraenoic acid dehydrogenase activity	F	Catalysis of the reaction: 5-HETE + NADP(+) = 5-oxo-ETE + NADPH + H(+).
97266	phenylacetyl-CoA 1,2-epoxidase activity	F	Catalysis of the reaction: phenylacetyl-CoA + H(+) + NADPH + O2 = 2-(1,2-epoxy-1,2-dihydrophenyl)acetyl-CoA + H2O + NADP(+).
97267	omega-hydroxylase P450 pathway	P	The chemical reactions and pathways by which arachidonic acid is converted to other compounds initially by omega-hydroxylation.
97268	cytoophidium	C	A subcellular filamentary structure where CTP synthase is compartmentalized in a range of organisms including bacteria, yeast, fruit fly, rat and human.
97269	all-trans-decaprenyl-diphosphate synthase activity	F	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate + 7 isopentenyl diphosphate = 7 diphosphate + all-trans-decaprenyl diphosphate.
97270	dishabituation	P	The temporary recovery of response to a stimulus when a novel stimulus is added.
97271	protein localization to bud neck	P	A process in which a protein is transported to, or maintained at, a location within a cellular bud neck.
97272	ammonia homeostasis	P	Any biological process involved in the maintenance of an internal steady state of ammonia.
97273	creatinine homeostasis	P	Any biological process involved in the maintenance of an internal steady state of creatinine.
97274	urea homeostasis	P	Any biological process involved in the maintenance of an internal steady state of urea.
97275	cellular ammonia homeostasis	P	Any biological process involved in the maintenance of an internal steady state of ammonia at the level of the cell.
97276	cellular creatinine homeostasis	P	Any biological process involved in the maintenance of an internal steady state of creatinine at the level of the cell.
97277	cellular urea homeostasis	P	Any biological process involved in the maintenance of an internal steady state of urea at the level of the cell.
97278	complement-dependent cytotoxicity	P	Lysis of a cell resulting from triggering of the complement cascade. An example can be seen with complement activation and subsequent lysis of a bacterial cell as a result of the binding of IgM to the cell surface followed by the binding of complement proteins to that antibody.
97279	histamine secretion mediated by IgE immunoglobulin	P	Histamine release triggered by the binding of an antigen to an IgE immunoglobulin bound to the cell surface. An example is mast cell histamine degranulation as a result of exposure of mast cell-bound IgE to alder tree pollen.
97280	histamine secretion mediated by immunoglobulin	P	Histamine release triggered by the binding of an antigen to an immunoglobulin bound to the cell surface.
97281	immune complex formation	P	The process that gives rise to an immune complex. Immune complexes are clusters of antibodies bound to antigen, to which complement may also be fixed, and which may precipitate or remain in solution. Examples are the clumping of cells such as bacteria or red blood cells in the presence of an antibody, precipitation of a toxin after an antibody binds to it, and clumping of viral particles as a result of antibody binding to the virus.
97282	immunoglobulin-mediated neutralization	P	The inhibition of an antigen's biological effects by antibody binding to it. An example is neutralization of diphtheria toxin by preventing its entry into human cells via the binding of antibody specific for diphtheria toxin.
97283	keratinocyte apoptotic process	P	Any apoptotic process in a keratinocyte. A keratinocyte is an epidermal cell which synthesizes keratin and undergoes a characteristic change as it moves upward from the basal layers of the epidermis to the cornified (horny) layer of the skin.
97284	hepatocyte apoptotic process	P	Any apoptotic process in a hepatocyte, the main structural component of the liver.
97286	iron ion import	P	The directed movement of iron ions into a cell or organelle.
97287	7-cyano-7-deazaguanine metabolic process	P	The chemical reactions and pathways involving the Q nucleoside precursor 7-cyano-7-deazaguanine, also known as 2-amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile or preQo.
97288	7-cyano-7-deazaguanine biosynthetic process	P	The chemical reactions and pathways resulting in the formation of the Q nucleoside precursor 7-cyano-7-deazaguanine, also known as 2-amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile or preQo.
97289	alpha-ribazole metabolic process	P	The chemical reactions and pathways involving alpha-ribazole, the benzimidazole nucleoside in adenosyl cobalamin (vitamin B12).
97290	alpha-ribazole biosynthetic process	P	The chemical reactions and pathways resulting in the formation of alpha-ribazole, the benzimidazole nucleoside in adenosyl cobalamin (vitamin B12).
97291	renal phosphate ion absorption	P	A renal system process in which phosphate ions are taken up from the collecting ducts and proximal and distal loops of the nephron. In non-mammalian species, absorption may occur in related structures.
97292	XMP metabolic process	P	The chemical reactions and pathways involving XMP, xanthosine monophosphate.
97293	XMP biosynthetic process	P	The chemical reactions and pathways resulting in the formation of XMP, xanthosine monophosphate.
97294	'de novo' XMP biosynthetic process	P	The chemical reactions and pathways resulting in the formation of XMP, xanthosine monophosphate, from simpler precursors.
97295	morphine biosynthetic process	P	The chemical reactions and pathways resulting in the formation of morphine, 17-methyl-7,8-didehydro-4,5alpha-epoxymorphinan-3,6alpha-diol. Morphine is a highly potent opiate analgesic psychoactive drug obtained form the opium poppy, Papaver somniferum.
97296	activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway	P	Any process that initiates the activity of an inactive cysteine-type endopeptidase involved in the apoptotic signaling pathway.
97297	activation of cysteine-type endopeptidase activity involved in execution phase of apoptosis	P	Any process that initiates the activity of an inactive cysteine-type endopeptidase involved in the execution phase of apoptosis.
97298	regulation of nucleus size	P	Any process that modulates the size of the nucleus.
97299	cysteine-type endopeptidase activity involved in plant-type hypersensitive response	F	Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile, and contributing to plant-type hypersensitive response, the rapid, localized death of plant cells in response to invasion by a pathogen.
97300	programmed necrotic cell death	P	A necrotic cell death process that results from the activation of endogenous cellular processes, such as signaling involving death domain receptors or Toll-like receptors.
97301	regulation of potassium ion concentration by positive regulation of transcription from RNA polymerase II promoter	P	Any process that regulates the internal concentration of potassium ions at the level of a cell by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter.
97302	lipoprotein biosynthetic process via diacylglyceryl transfer	P	The chemical reactions and pathways by which diacylglyceryl transfer leads to formation of a water-soluble protein-lipid complex.
97303	lipoprotein biosynthetic process via N-acyl transfer	P	The chemical reactions and pathways by which N-acyl transfer leads to formation of a water-soluble protein-lipid complex.
97304	lipoprotein biosynthetic process via signal peptide cleavage	P	The chemical reactions and pathways by which signal peptide cleavage leads to formation of a water-soluble protein-lipid complex.
97305	response to alcohol	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alcohol stimulus.
97306	cellular response to alcohol	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alcohol stimulus.
97307	response to farnesol	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a farnesol stimulus.
97308	cellular response to farnesol	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a farnesol stimulus.
97309	cap1 mRNA methylation	P	Methylation of the ribose of the first nucleotide of a 5'-capped mRNA.
97310	cap2 mRNA methylation	P	Methylation of the ribose of the first and second nucleotides of a 5'-capped mRNA.
97311	biofilm matrix	C	A structure lying external to bacterial cells. A biofilm is an aggregate of surface-associated bacteria, and the biofilm matrix is the envelope of polymeric substances that surrounds the bacteria.
97312	biofilm matrix component	C	Any constituent part of the biofilm matrix, a structure lying external to bacterial cells. A biofilm is an aggregate of surface-associated bacteria, and the biofilm matrix is the envelope of polymeric substances that surrounds the bacteria.
97313	biofilm matrix surface	C	The external part of the biofilm matrix, a structure lying external to bacterial cells. A biofilm is an aggregate of surface-associated bacteria, and the biofilm matrix is the envelope of polymeric substances that surrounds the bacteria.
97314	apoptosome assembly	P	The aggregation, arrangement and bonding together of the apoptosome, a multisubunit protein complex involved in the signaling phase of the apoptotic process.
97315	response to N-acetyl-D-glucosamine	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an N-acetyl-D-glucosamine stimulus.
97316	cellular response to N-acetyl-D-glucosamine	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an N-acetyl-D-glucosamine stimulus.
97317	invasive growth in response to biotic stimulus	P	The growth of colonies in filamentous chains of cells as a result of a biotic stimulus. An example of this is Candida albicans forming invasive filaments in agar medium in response to a serum stimulus.
97318	invasive growth in response to abiotic stimulus	P	The growth of colonies in filamentous chains of cells as a result of a abiotic stimulus. An example of this process is found in Candida albicans.
97319	carbohydrate import into cell	P	The directed movement of carbohydrate from outside of a cell into the cytoplasmic compartment. This may occur via transport across the plasma membrane or via endocytosis.
97320	plasma membrane tubulation	P	A membrane tubulation process occurring in a plasma membrane.
97321	cell growth mode switching, filamentous to budding	P	The process in which a cell switches from growing as a filament (elongated cells attached end-to-end) to growing as a round budding cell. An example of this is observed in Candida albicans.
97322	7SK snRNA binding	F	Interacting selectively and non-covalently with a 7SK small nuclear RNA (7SK snRNA).
97323	B cell adhesion	P	The attachment of a B cell to another cell via adhesion molecules.
97324	melanocyte migration	P	The orderly movement of melanocytes from one site to another, often during the development of a multicellular organism. A melanocyte is a pigment cell derived from the neural crest. It contains melanin-filled pigment granules, which give a brown to black appearance.
97325	melanocyte proliferation	P	The multiplication or reproduction of melanocytes, resulting in the expansion of a cell population. A melanocyte is a pigment cell derived from the neural crest. It contains melanin-filled pigment granules, which give a brown to black appearance.
97326	melanocyte adhesion	P	The attachment of a melanocyte to another cell via adhesion molecules.
97327	response to antineoplastic agent	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antineoplastic agent stimulus. An antineoplastic agent is a substance that inhibits or prevents the proliferation of neoplasms.
97328	response to carboplatin	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carboplatin stimulus.
97329	response to antimetabolite	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antimetabolite stimulus. An antimetabolite is a substance which is structurally similar to a metabolite but which competes with it or replaces it, and so prevents or reduces its normal utilization.
97330	response to 5-fluoro-2'-deoxyuridine	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 5-fluoro-2'-deoxyuridine stimulus. 5-fluoro-2'-deoxyuridine is a pyrimidine 2'-deoxyribonucleoside compound having 5-fluorouracil as the nucleobase; it is used to treat hepatic metastases of gastrointestinal adenocarcinomas and for palliation in malignant neoplasms of the liver and gastrointestinal tract.
97331	response to cytarabine	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytarabine stimulus.
97332	response to antipsychotic drug	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antipsychotic drug stimulus. Antipsychotic drugs are agents that control agitated psychotic behaviour, alleviate acute psychotic states, reduce psychotic symptoms, and exert a quieting effect.
97333	response to olanzapine	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an olanzapine stimulus.
97334	response to perphenazine	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a perphenazine stimulus. Perphenazine is a phenothiazine derivative having a chloro substituent at the 2-position and a 3-[4-(2-hydroxyethyl)piperazin-1-yl]propyl group at the N-10 position.
97335	response to quetiapine	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a quetiapine stimulus.
97336	response to risperidone	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a risperidone stimulus.
97337	response to ziprasidone	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ziprasidone stimulus. Ziprasidone is a piperazine compound having 1,2-benzothiazol-3-yl- and 2-(6-chloro-1,3-dihydro-2-oxindol-5-yl)ethyl substituents attached to the nitrogen atoms.
97338	response to clozapine	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a clozapine stimulus.
97339	glycolate transmembrane transport	P	A process in which glycolate is transported from one side of a membrane to the other by means of some agent such as a transporter or pore. Glycolate is the anion of hydroxyethanoic acid (glycolic acid).
97340	inhibition of cysteine-type endopeptidase activity	P	Any process that prevents the activation of an inactive cysteine-type endopeptidase.
97341	zymogen inhibition	P	Any process that prevents the proteolytic processing of an inactive enzyme to an active form.
97342	ripoptosome	C	A protein complex whose core components are the receptor-interacting serine/threonine-protein kinases RIPK1 and RIPK3 (also called RIP1 and RIP3). Formation of the ripoptosome can induce an extrinsic apoptotic signaling pathway or a necroptotic signaling pathway. The composition of this protein complex may depend on several factors including nature of the signal, cell type and more.
97343	ripoptosome assembly	P	The aggregation, arrangement and bonding together of a set of components to form a ripoptosome, a protein complex whose formation can induce an extrinsic apoptotic signaling pathway or a necroptotic signaling pathway. The composition of this protein complex may depend on several factors including nature of the signal, cell type and more.
97344	Rix1 complex	C	A protein complex that comprises Rix1p, Ipi1p and Ipi3p, and is required for processing of ITS2 sequences from 35S pre-rRNA. The Rix1 complex has been identified in budding yeast and fission yeast, and members of this complex are conserved in higher eukaryotes.
97345	mitochondrial outer membrane permeabilization	P	The process by which the mitochondrial outer membrane becomes permeable to the passing of proteins and other molecules from the intermembrane space to the cytosol as part of the apoptotic signaling pathway.
97346	INO80-type complex	C	A chromatin remodeling protein complex initially purified from S. cerevisiae and containing more than 10 subunits, including the SWR1-related complexes. INO80 (inositol requiring 80)-type complexes have diverse functions, including promoting transcriptional activation and DNA repair.
97347	TAM protein secretion complex	C	A heterooligomeric protein complex that spans the bacterial periplasm and enables the secretion of adhesin proteins in Gram-negative bacteria. In Citrobacter rodentium, Salmonella enterica and Escherichia coli, the TAM complex consists of an Omp85-family protein, TamA, in the outer membrane and TamB in the inner membrane.
97348	host cell endocytic vesicle membrane	C	The lipid bilayer surrounding a host cell endocytic vesicle.
97350	neutrophil clearance	P	The selective elimination of senescent neutrophils from the body by autoregulatory mechanisms.
97351	toxin-antitoxin pair type II binding	F	Interacting selectively and non-covalently with a toxic protein, disabling its function. There may be more than one antitoxin to a toxic protein. Instances of this activity are known only in prokaryotes, where the toxic protein may be a ribonuclease, a DNA gyrase, or other.
97352	autophagosome maturation	P	The process in which autophagosomes, double-membraned vacuoles containing cytoplasmic material fuse with a vacuole (yeast) or lysosome (e.g. mammals and insects). In the case of yeast, inner membrane-bounded structures (autophagic bodies) appear in the vacuole. Fusion provides an acidic environment and digestive function to the interior of the autophagosome.
97353	centrolateral pattern formation	P	The regionalization process in which the areas along the centrolateral axis are established that will lead to differences in cell differentiation, or in which cells interpret a specific environment.
97354	prenylation	P	The covalent attachment of a prenyl group to a molecule; geranyl, farnesyl, or geranylgeranyl groups may be added.
97355	protein localization to heterochromatin	P	Any process in which a protein is transported to, or maintained at, a part of a chromosome that is organized into heterochromatin.
97356	perinucleolar compartment	C	The perinucleolar compartment (PNC) is a subnuclear structure associated with, but structurally distinct from, the nucleolus. The PNC contains large amounts of the heterogeneous nuclear ribonucleoprotein complex (hnRNP) called hnRNP 1 (PTB). Many RNA binding proteins as well as RNA polymerase III transcripts are highly enriched in this compartment. PTB and pol III transcripts are required for the integrity of the PNC.
97357	myo-inositol import into cell	P	The directed movement of myo-inositol from outside of a cell into the intracellular region of a cell.
97358	D-leucyl-tRNA(Leu) deacylase activity	F	Catalysis of the reaction: D-leucyl-tRNA(Leu) = D-leucine + tRNA(Leu). Hydrolysis of the removal of D-leucine from residues in charged tRNA(Leu).
97359	UDP-glucosylation	P	The covalent attachment of a UDP-glucose residue to a substrate molecule.
97360	chorionic trophoblast cell proliferation	P	The multiplication or reproduction of chorionic trophoblast cells, resulting in the expansion of their population.
97361	CIA complex	C	The cytosolic iron-sulfur protein assembly (CIA) complex mediates the incorporation of iron-sulfur clusters into apoproteins involved in DNA metabolism and genomic integrity.
97362	MCM8-MCM9 complex	C	A hexameric protein complex composed of MCM8 and MCM9 and involved in homologous recombination repair following DNA interstrand cross-links.
97363	protein O-GlcNAc transferase activity	F	Catalysis of the reaction: UDP-N-acetyl-D-glucosamine + [protein]-L-serine = UDP + [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-serine, or UDP-N-acetyl-D-glucosamine + [protein]-L-threonine = UDP + [protein]-3-O-(N-acetyl-D-glucosaminyl)-L-threonine.
97364	stretch-activated, cation-selective, calcium channel activity involved in regulation of action potential	F	Enables the transmembrane transfer of a calcium ion by a channel that opens in response to a mechanical stress in the form of stretching, and contributing to the regulation of action potential.
97365	stretch-activated, cation-selective, calcium channel activity involved in regulation of cardiac muscle cell action potential	F	Enables the transmembrane transfer of a calcium ion by a channel that opens in response to a mechanical stress in the form of stretching, and contributing to the regulation of action potential in a cardiac muscle cell.
97366	response to bronchodilator	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bronchodilator stimulus. A bronchodilator is a chemical that causes an increase in the expansion of a bronchus or bronchial tubes.
97367	carbohydrate derivative binding	F	Interacting selectively and non-covalently with a carbohydrate derivative.
97368	establishment of Sertoli cell barrier	P	Establishment of a structure near the basement membrane in adjacent Sertoli cells of the seminiferous epithelium for maintaining spermatogenesis. The structure consists of tight junctions, basal ectoplasmic specializations, and desmosome-like junctions.
97369	sodium ion import	P	The directed movement of sodium ions into a cell or organelle.
97370	protein O-GlcNAcylation via threonine	P	The glycosylation of a protein by addition of N-acetylglucosamine via the O3 atom of peptidyl-threonine, forming O3-N-acetylglucosamine-L-threonine.
97371	MDM2/MDM4 family protein binding	F	Interacting selectively and non-covalently with any isoform of the MDM2/MDM4 protein family, comprising negative regulators of p53.
97372	NAD-dependent histone deacetylase activity (H3-K18 specific)	F	Catalysis of the reaction: histone H3 N6-acetyl-L-lysine (position 18) + H2O = histone H3 L-lysine (position 18) + acetate. This reaction requires the presence of NAD, and represents the removal of an acetyl group from lysine at position 18 of the histone H3 protein.
97373	MCM core complex	C	A protein complex that contains Mcm4, Mcm6, and Mcm7 proteins, and possesses DNA helicase activity. In the heterohexameric MCM complex, the Mcm4/6/7 proteins form a stable core, and Mcm2, Mcm3, and Mcm5 are more peripherally associated.
97374	sensory neuron axon guidance	P	The process in which the migration of an axon growth cone of a sensory neuron is directed to a specific target site in response to a combination of attractive and repulsive cues. A sensory neuron is an afferent neuron conveying sensory impulses.
97375	spinal sensory neuron axon guidance	P	The process in which the migration of an axon growth cone of a spinal sensory neuron is directed to a specific target site in response to a combination of attractive and repulsive cues. A spinal sensory neuron is a sensory neuron that project to the spinal cord.
97376	interneuron axon guidance	P	The process in which the migration of an axon growth cone of an interneuron is directed to a specific target site in response to a combination of attractive and repulsive cues. An interneuron is any neuron which is not motor or sensory. Interneurons may also refer to neurons whose axons remain within a particular brain region, as contrasted with projection neurons which have axons projecting to other brain regions.
97377	spinal cord interneuron axon guidance	P	The process in which the migration of an axon growth cone of a spinal cord interneuron is directed to a specific target site in response to a combination of attractive and repulsive cues. A spinal cord interneuron is a CNS interneuron located in the spinal cord.
97378	dorsal spinal cord interneuron axon guidance	P	The process in which the migration of an axon growth cone of a dorsal spinal cord interneuron is directed to a specific target site in response to a combination of attractive and repulsive cues. A dorsal spinal cord interneuron is an interneuron located in the dorsal part of the spinal cord.
97379	dorsal spinal cord interneuron posterior axon guidance	P	The process in which the migration of an axon growth cone of a dorsal spinal cord interneuron is directed to a specific target site in the posterior direction along the anterior-posterior body axis in response to a combination of attractive and repulsive cues. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism.
97380	dorsal spinal cord interneuron anterior axon guidance	P	The process in which the migration of an axon growth cone of a dorsal spinal cord interneuron is directed to a specific target site in the anterior direction along the anterior-posterior body axis in response to a combination of attractive and repulsive cues. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism.
97381	photoreceptor disc membrane	C	Ovally-shaped membranous stack located inside the photoreceptor outer segment, and containing densely packed molecules of the photoreceptor protein rhodopsin that traverse the lipid bilayer. Disc membranes are apparently derived from the plasma membrane in the region of the cilium that connects the photoreceptor outer segment to the inner segment.
97382	deoxynucleoside-diphosphatase activity	F	Catalysis of the reaction: a deoxynucleoside diphosphate + H2O = a deoxynucleotide + phosphate.
97383	dIDP diphosphatase activity	F	Catalysis of the reaction: dIDP + H2O = dIMP + phosphate.
97384	cellular lipid biosynthetic process	P	The chemical reactions and pathways resulting in the formation of lipids, as carried out by individual cells.
97385	programmed necrotic cell death in response to starvation	P	A programmed necrotic cell death occurring as a result of a starvation stimulus (deprivation of nourishment).
97386	glial cell projection	C	A prolongation or process extending from a glial cell.
97387	capitate projection	C	Simple or compound process of epithelial glial cells with a spherical head that inserts into photoreceptor axons. Capitate projections have only been observed in Brachycera (flies).
97388	chemokine (C-C motif) ligand 19 production	P	The appearance of chemokine (C-C motif) ligand 19 (CCL19) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
97389	chemokine (C-C motif) ligand 21 production	P	The appearance of chemokine (C-C motif) ligand 21 (CCL21) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
97390	chemokine (C-X-C motif) ligand 12 production	P	The appearance of chemokine (C-X-C motif) ligand 12 (CXCL12) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
97391	chemokine (C-X-C motif) ligand 13 production	P	The appearance of chemokine (C-X-C motif) ligand 13 (CXCL13) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
97392	chemokine (C-X-C motif) ligand 16 production	P	The appearance of chemokine (C-X-C motif) ligand 16 (CXCL16) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels.
97393	telomeric repeat-containing RNA transcription	P	The synthesis of telomeric repeat-containing RNA from a DNA template. A telomere is a complex of DNA and proteins that seals the end of a chromosome.
97394	telomeric repeat-containing RNA transcription from RNA pol II promoter	P	The synthesis of telomeric repeat-containing RNA from a DNA template by RNA Polymerase II (Pol II), originating at a Pol II promoter.
97395	response to interleukin-32	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-32 stimulus.
97396	response to interleukin-17	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-17 stimulus.
97397	cellular response to interleukin-32	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-32 stimulus.
97398	cellular response to interleukin-17	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-17 stimulus.
97399	interleukin-32-mediated signaling pathway	P	A series of molecular signals initiated by the binding of interleukin-32 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.
97400	interleukin-17-mediated signaling pathway	P	A series of molecular signals initiated by the binding of interleukin-17 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.
97401	synaptic vesicle lumen acidification	P	The acidification of the synaptic vesicle lumen via transport of protons into the vesicle. The resulting electrochemical gradient powers neurotransmitter loading.
97402	neuroblast migration	P	The orderly movement of a neuroblast from one site to another, often during the development of a multicellular organism or multicellular structure. A neuroblast is any cell that will divide and give rise to a neuron.
97403	cellular response to raffinose	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a raffinose stimulus.
97404	succinate import into cell	P	The directed movement of succinate from outside of a cell into the cytoplasmic compartment. This may occur via transport across the plasma membrane or via endocytosis.
97405	malate import into cell	P	The directed movement of malate from outside of a cell into the intracellular region of a cell.
97406	malonic acid import into cell	P	The directed movement of malonic acid from outside of a cell into the cytoplasmic compartment. This may occur via transport across the plasma membrane or via endocytosis.
97407	Bunina body	C	Small granular inclusions (about 1-3 microns in diameter) found in the anterior horn cells, and appearing either singly or in a group. Sometimes they are arranged in small beaded chains. Bunina bodies express cystatin C and consist of electron-dense amorphous material that contains tubules or vesicular structures. The amorphous material frequently includes a cytoplasmic island containing neurofilaments and other micro-organelles.
97408	fibrillary inclusion	C	Cellular inclusion consisting of circular areas filled with fine slender filaments about 10 nanometers in diameter, delimited by a wall of varying complexity (either a single continuous membrane or a tubular network consisting of a fine filamentous material giving the wall a honeycomb appearance). Fibrillary inclusions are found in the cytoplasm of giant cells of Dieters in the lateral vestibular nucleus of the rat; similar structures have been described in the ventral cochlear nucleus, spinal cord, and substantia nigra.
97409	glial cytoplasmic inclusion	C	Non-membrane-bound cytoplasmic inclusions composed of 10-40 nm granule-coated fibrils. These inclusions have an abnormal accumulation of alpha-synuclein protein and are found in association with multiple system atrophy.
97410	hippocampal interneuron differentiation	P	The process in which a relatively unspecialized cell acquires specialized features of a hippocampal interneuron.
97411	hypoxia-inducible factor-1alpha signaling pathway	P	A series of molecular signals mediated by hypoxia-inducible factor (HIF1) in response to lowered oxygen levels (hypoxia). Under hypoxic conditions, the oxygen-sensitive alpha-subunit of hypoxia-inducible factor (HIF)-1 dimerizes with a HIF1-beta subunit (also called ARNT or aryl-hydrocarbon-receptor nuclear translocator), translocates to the nucleus and activates transcription of genes whose products participate in responding to hypoxia.
97412	hyaline inclusion	C	A glass-like, pale intracellular inclusion.
97413	Lewy body	C	Cytoplasmic, spherical inclusion commonly found in damaged neurons, and composed of abnormally phosphorylated, neurofilament proteins aggregated with ubiquitin and alpha-synuclein.
97414	classical Lewy body	C	Cytoplasmic inclusion, 5 to 15 micrometers in diameter, with a dense core surrounded by a halo of 10 to 20 nm wide radially oriented alpha-synuclein fibrils.
97415	cortical Lewy body	C	Cytoplasmic inclusion similar to a classical Lewy body but lacking a halo of protein fibrils.
97416	Lewy body-like hyaline inclusion	C	Cytoplasmic inclusion found in neurons. It consists of filaments and granular materials, exhibits a dense core with a rough peripheral halo and lacks a limiting membrane. The filaments of these inclusions are composed of approximately 15-25 nm granule-coated fibrils in association with normal 10-nm neurofilaments.
97417	nematosome	C	Cytoplasmic, ball-like inclusion resembling a nucleolus and consisting of a convoluted network of electron-opaque strands embedded in a less dense matrix. It measures approximately 0.9 microns and lacks a limiting membrane. Its strands (diameter = 400-600 A) appear to be made of an entanglement of tightly packed filaments and particles approximately 25-50 A thick. Cytochemical studies suggest the presence of nonhistone proteins and some RNA. Usually only one such structure is present in a cell, and it appears to occur in most ganglion cells. Although they can be seen anywhere in the cell body, nematosomes are typically located in the perinuclear cytoplasm, where they are often associated with smooth-surfaced and coated vesicles.
97418	neurofibrillary tangle	C	Intracellular mass of paired, helically wound protein filaments (also called PHF) lying in the cytoplasm of neuronal cell bodies and neuritic cell processes. Neurofibrillary tangles contain an abnormally phosphorylated form of a microtubule-associated protein, tau. The shape of these inclusions may resemble a flame or a star.
97419	Pick body	C	Cellular inclusion composed of numerous tau fibrils arranged in a disorderly array. Tau protein is a major component, though Pick bodies also contain ubiquitin, alpha-synuclein, and apolipoprotein E.
97420	skein-like inclusion	C	Intracytoplasmic filamentous structure frequently encountered in preparations immunostained for ubiquitin.
97421	liver regeneration	P	The regrowth of lost or destroyed liver.
97422	tubular endosome	C	A network of fine tubules in the vicinity of the Golgi complex and around the centriole.
97423	mitochondrion-associated adherens complex	C	An organelle arrangement comprised of the following elements: a mitochondrion positioned near the presynaptic membrane; an electron-dense mitochondrial plaque adjacent to the outer mitochondrial membrane that faces the presynaptic membrane; filament-like elements appearing to link the mitochondrial plaque to a cell-cell junction region (sometimes termed punctum adherens); tubular or vesicular-appearing membrane (also called vesicular chain) interposed among the filaments. Mitochondrion-associated adherens complexes were initially described in the dorsal horn of the spinal cord. They are found in calyces and other large terminals of the auditory brainstem, and in a variety of mammalian species including humans.
97424	nucleolus-associated heterochromatin	C	Dense particles of heterochromatin, consisting of a loosely twisted strand about 600 Angstrom thick, found associated with the nucleolus.
97425	smooth endoplasmic reticulum part	C	Any constituent part of the smooth endoplasmic reticulum (also called smooth ER, or SER).
97426	glial filament	C	An intermediate filament composed of glial fibrillary acidic protein (GFAP) and found in astrocytes.
97427	microtubule bundle	C	An arrangement of closely apposed microtubules running parallel to each other.
97428	protein maturation by iron-sulfur cluster transfer	P	The transfer of an assembled iron-sulfur cluster from a scaffold protein to an acceptor protein that contributes to the attainment of the full functional capacity of a protein.
97429	amino acid ligation activity by nonribosomal peptide synthase	F	Catalysis of the ligation of an amino acid to another amino acid via a carbon-nitrogen bond, with the concomitant hydrolysis of the diphosphate bond in ATP or a similar triphosphate, carried out by a nonribosomal peptide synthase.
97430	copper ion import into ascospore-type prospore	P	The directed movement of copper ions into an ascospore-type prospore.
97431	mitotic spindle pole	C	Either of the ends of a mitotic spindle, a spindle that forms as part of mitosis, where spindle microtubules are organized; usually contains a microtubule organizing center and accessory molecules, spindle microtubules and astral microtubules.
97432	hippocampal pyramidal neuron differentiation	P	The process in which a relatively unspecialized cell acquires specialized features of a hippocampal pyramidal neuron, a pyramidal cell of the hippocampus.
97433	dense body	C	An electron dense body which may contain granules.
97434	succinate:proton symporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: succinate(out) + H+(out) = succinate(in) + H+(in).
97435	supramolecular fiber organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a supramolecular fiber, a polymer consisting of an indefinite number of protein or protein complex subunits that have polymerised to form a fiber-shaped structure.
97436	entry into dormancy	P	The dormancy process that results in entry into dormancy. Dormancy (sometimes called a dormant state) is a suspension of most physiological activity and growth that can be reactivated.
97437	maintenance of dormancy	P	The dormancy process that results in an organism remaining in dormancy. Dormancy (sometimes called a dormant state) is a suspension of most physiological activity and growth that can be reactivated.
97438	exit from dormancy	P	The dormancy process that results in exit from dormancy. Dormancy (sometimes called a dormant state) is a suspension of most physiological activity and growth that can be reactivated.
97439	acquisition of desiccation tolerance	P	The process in which tolerance to severe drying is acquired, before entering into a dry, either dormant or quiescent state.
97440	apical dendrite	C	A dendrite that emerges near the apical pole of a neuron. In bipolar neurons, apical dendrites are located on the opposite side of the soma from the axon.
97441	basilar dendrite	C	A dendrite that emerges near the basal pole of a neuron. In bipolar neurons, basal dendrites are either on the same side of the soma as the axon, or project toward the axon.
97442	CA3 pyramidal cell dendrite	C	A dendrite of a hippocampal CA3 pyramidal cell.
97443	sorting endosome	C	A multivesicular body surrounded by and connected with multiple tubular compartments with associated vesicles.
97444	spine apparatus	C	A specialization of the endomembrane system found in some classes of dendritic spines consisting of two or more closely apposed lamellae with interspersed electron dense material. The endomembrane component is continuous with the smooth endoplasmic reticulum.
97445	presynaptic active zone dense projection	C	Electron dense projection extending from the cytomatrix into the cytoplasm on which synaptic vesicles are tethered.
97446	protein localization to eisosome filament	P	A process in which a protein is transported to, and/or maintained in, a specific location in a eisosome filament (also called linear eisosome), a filamentous cortical structure formed, in S. pombe, by the eisosome component Pil1.
97447	dendritic tree	C	The entire complement of dendrites for a neuron, consisting of each primary dendrite and all its branches.
97448	spine mat	C	A configuration of neuron spines found on ciliary ganglion neurons in the embryonic and adult brain consisting of patches of closely spaced spines lying flat against the soma.
97449	astrocyte projection	C	A prolongation or process extending from the soma of an astrocyte and wrapping around neurons.
97450	astrocyte end-foot	C	Terminal process of astrocyte abutting non-neuronal surfaces in the brain.
97451	glial limiting end-foot	C	Terminal process of astrocyte that extends to the surface of the central nervous system. Together, glial limiting end-feet form the glial limiting membrane or glia limitans.
97452	GAIT complex	C	A protein complex which mediates interferon-gamma-induced transcript-selective translation inhibition in inflammation processes. The complex binds to stem loop-containing GAIT elements in the 3'-UTR of diverse inflammatory mRNAs and suppresses their translation by blocking the recruitment of the 43S ribosomal complex to m7G cap-bound eIF4G. In humans it includes RPL13A, EPRS, SYNCRIP and GAPDH; mouse complexes lack SYNCRIP.
97453	mesaxon	C	Portion of the ensheathing process (either myelin or non-myelin) where the enveloping lips of the ensheathing cell come together so that their apposed plasma membranes run parallel to each other, separated by a cleft 12 nm wide.
97454	Schwann cell microvillus	C	Small finger-like extension of a Schwann cell that contacts the nodal membrane.
97455	spiny bracelet of Nageotte	C	Paranodal terminations of Schwann cells that do not directly contact the paranodal axon membrane. Usually found in thicker myelin.
97456	terminal loop	C	Portion of myelin-forming Schwann cell consisting of terminal cytoplasmic extensions adhered to the axon at the beginning and end of the myelin sheath.
97457	hippocampal mossy fiber	C	Axon of dentate gyrus granule cell projecting to hippocampal area CA3, characterized by expansions (mossy fiber expansions) giving the fibers a mossy appearance. These unmyelinated axons were first described by Ramon y Cajal.
97458	neuron part	C	Any constituent part of a neuron, the basic cellular unit of nervous tissue. A typical neuron consists of a cell body (often called the soma), an axon, and dendrites. Their purpose is to receive, conduct, and transmit impulses in the nervous system.
97459	iron ion import into cell	P	The directed movement of iron ions from outside of a cell into the cytoplasmic compartment. This may occur via transport across the plasma membrane or via endocytosis.
97460	ferrous iron import into cell	P	The directed movement of ferrous iron (Fe(II) or Fe2+) ions from outside of a cell into the cytoplasmic compartment. This may occur via transport across the plasma membrane or via endocytosis.
97461	ferric iron import into cell	P	The directed movement of ferric iron (Fe(III) or Fe3+) ions from outside of a cell into the cytoplasmic compartment. This may occur via transport across the plasma membrane or via endocytosis.
97462	Lewy neurite	C	Elongated neuronal process, often with side branches and more than one branching point, described in brains of patients with Parkinson's disease. Lewy neurites stain positively for ubiquitin in brainstem and forebrain regions affected in Parkinson's disease.
97463	gemmule	C	Spine-like process found on some neurons, e.g., periglomerular cells of olfactory cortex.
97464	thorny excrescence	C	Large complex spine protruding from a dendrite. Each excrescence is formed by a cluster of spine heads.
97465	somatic spine	C	Spine emanating from the cell soma of a neuron.
97466	glycoprotein ERAD pathway	P	An ERAD pathway whereby endoplasmic reticulum (ER)-resident glycoproteins are targeted for degradation. Includes differential processing of the glycoprotein sugar chains, retrotranslocation to the cytosol and degradation by the ubiquitin-proteasome pathway. A glycoprotein is a compound in which a carbohydrate component is covalently bound to a protein component.
97467	type III terminal bouton	C	Terminal inflated portion of the axon of a non-glutamatergic neuron, containing the specialized apparatus necessary to release neurotransmitters at a regulatory synapse. The axon terminus is considered to be the whole region of thickening and the terminal bouton is a specialized region of it. Type III terminal boutons are larger than type II ones.
97468	programmed cell death in response to reactive oxygen species	P	Cell death resulting from activation of endogenous cellular processes and occurring as a result of a reactive oxygen species stimulus. Reactive oxygen species include singlet oxygen, superoxide, and oxygen free radicals.
97470	ribbon synapse	C	Type of synapse characterized by an electron-dense ribbon, lamella (bar) or spherical body in the presynaptic process cytoplasm.
97471	mossy fiber rosette	C	A synapse of a mossy fiber onto the dendrite of a granule cell; each mossy fiber can have up to 50 rosettes.
97472	cyclin-dependent protein kinase activity	F	Catalysis of the phosphorylation of an amino acid residue in a protein, usually according to the reaction: a protein + ATP = a phosphoprotein + ADP. This reaction requires the binding of a regulatory cyclin subunit and full activity requires stimulatory phosphorylation by a CDK-activating kinase (CAK).
97473	retinal rod cell apoptotic process	P	Any apoptotic process in a retinal rod cell, one of the two photoreceptor cell types of the vertebrate retina.
97474	retinal cone cell apoptotic process	P	Any apoptotic process in a retinal cone cell, one of the two photoreceptor cell types of the vertebrate retina.
97475	motor neuron migration	P	The orderly movement of a motor neuron from one site to another. A motor neuron is an efferent neuron that passes from the central nervous system or a ganglion toward or to a muscle and conducts an impulse that causes movement.
97476	spinal cord motor neuron migration	P	The orderly movement of a spinal cord motor neuron from one site to another. A spinal cord motor neuron is a motor neuron that passes from the spinal cord toward or to a muscle and conducts an impulse that causes movement.
97477	lateral motor column neuron migration	P	The orderly movement of a lateral motor column neuron from one site to another. A lateral motor column neuron is a motor neuron that is generated only on limb levels and send axons into the limb mesenchyme.
97478	leaflet of membrane bilayer	C	Any of the two layers of lipid molecules that constitute a membrane.
97479	synaptic vesicle localization	P	Any process in which a synaptic vesicle or vesicles are transported to, and/or maintained in, a specific location.
97480	establishment of synaptic vesicle localization	P	The directed movement of a synaptic vesicle or vesicles to a specific location.
97482	muscle cell postsynaptic density	C	A postsynaptic specialization that is part of a neuromuscular junction.
97484	dendrite extension	P	Long distance growth of a single dendrite involved in cellular development.
97485	neuron projection guidance	P	The process in which the migration of a neuron projection is directed to a specific target site in response to a combination of attractive and repulsive cues.
97486	multivesicular body lumen	C	The volume enclosed by the outermost membrane of a multivesicular body.
97487	multivesicular body, internal vesicle	C	A membrane-bounded vesicle wholly contained within a multivesicular body.
97488	multivesicular body, internal vesicle membrane	C	The lipid bilayer surrounding a multivesicular body internal vesicle.
97489	multivesicular body, internal vesicle lumen	C	The volume enclosed by the membrane of the multivesicular body internal vesicle.
97490	sympathetic neuron projection extension	P	Long distance growth of a single sympathetic neuron projection involved in cellular development. A neuron projection is a prolongation or process extending from a nerve cell, e.g. an axon or dendrite.
97491	sympathetic neuron projection guidance	P	The process in which the migration of a sympathetic neuron projection is directed to a specific target site in response to a combination of attractive and repulsive cues.
97492	sympathetic neuron axon guidance	P	The chemotaxis process that directs the migration of a sympathetic neuron axon growth cone to a specific target site in response to a combination of attractive and repulsive cues.
97493	structural molecule activity conferring elasticity	F	The action of a molecule that contributes to the structural integrity of a complex or assembly within or outside a cell, providing elasticity and recoiling.
97494	regulation of vesicle size	P	Any process that modulates the size of a vesicle.
97495	H-NS-Hha complex	C	A trimeric protein complex made up of an H-NS homodimer and an Hha monomer. In Enterobacteriaceae, this complex negatively regulates transcription of a range of genes.
97496	blood vessel lumen ensheathment	P	A blood vessel lumenization process that occurs by blood vessel endothelial cells delaminating and aligning along the inner surface of an existing luminal space, extending the open ended lumen, and joining to other blood vessels to form a complete blood vessel.
97497	blood vessel endothelial cell delamination	P	The process of negative regulation of cell adhesion that results in blood vessel endothelial cells splitting off from an existing endothelial sheet.
97498	endothelial tube lumen extension	P	Any endothelial tube morphogenesis process by which the tube is increased in length.
97499	protein localization to non-motile cilium	P	A process in which a protein is transported to, or maintained in, a location within a non-motile cilium.
97500	receptor localization to non-motile cilium	P	A process in which a receptor is transported to, or maintained in, a location within a non-motile cilium.
97501	stress response to metal ion	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis caused by a metal ion stimulus.
97502	mannosylation	P	The covalent attachment of a mannose residue to a substrate molecule.
97503	sialylation	P	The covalent attachment of sialic acid to a substrate molecule.
97504	Gemini of coiled bodies	C	Nuclear bodies frequently found near or associated with Cajal bodies (also called coiled bodies or CBs). Gemini of coiled bodies, or 'gems', are similar in size and shape to CBs, and often indistinguishable under the microscope. Unlike CBs, gems do not contain small nuclear ribonucleoproteins (snRNPs); they contain a protein called survivor of motor neurons (SMN) whose function relates to snRNP biogenesis. Gems are believed to assist CBs in snRNP biogenesis, and to play a role in the etiology of spinal muscular atrophy (SMA).
97505	Rad6-Rad18 complex	C	A ubiquitin ligase complex found to be involved in post-replicative bypass of UV-damaged DNA and UV mutagenesis. In S. cerevisiae, the complex contains the ubiquitin conjugating enzyme Rad6 and Rad18, a protein containing a RING finger motif and a nucleotide binding motif. The yeast Rad6-Rad18 heterodimer has ubiquitin conjugating activity, binds single-stranded DNA, and possesses single-stranded DNA-dependent ATPase activity.
97506	deaminated base DNA N-glycosylase activity	F	DNA N-glycosylase activity acting on deaminated bases.
97507	hypoxanthine DNA N-glycosylase activity	F	DNA N-glycosylase activity acting on deaminated adenine (hypoxanthine).
97508	xanthine DNA N-glycosylase activity	F	DNA N-glycosylase activity acting on deaminated guanine (xanthine).
97509	oxanine DNA N-glycosylase activity	F	DNA N-glycosylase activity acting on deaminated guanine where the resulting base (oxanine) is generated by NO- or HNO2-induced nitrosative deamination.
97510	base-excision repair, AP site formation via deaminated base removal	P	A base-excision repair, AP site formation process occurring via excision of a deaminated base.
97511	dendritic cell dendrite	C	A branched cellular projection (or cytoplasmic extension) that is extended from the surface of a dendritic immune cell, and which enables the cell to sample luminal pathogens and increase the surface area for antigen presentation to T cells.
97512	cardiac myofibril	C	A cardiac myofibril is a myofibril specific to cardiac muscle cells.
97513	myosin II filament	C	A bipolar filament composed of myosin II molecules.
97514	sexual spore wall	C	A specialized envelope lying outside the cell membrane of a spore derived from a product of meiosis.
97515	asexual spore wall	C	A specialized envelope lying outside the cell membrane of a spore derived from an asexual process. Examples of this process are found in bacterial and fungal species.
97516	microvillar actin bundle	C	A parallel bundle of actin filaments at the core of a microvillus.
97517	contractile actin filament bundle	C	An actin filament bundle in which the filaments are loosely packed (approximately 30-60 nm apart) and arranged with opposing polarities; the loose packing allows myosin (usually myosin-II) to enter the bundle.
97518	parallel actin filament bundle	C	An actin filament bundle in which the filaments are tightly packed (approximately 10-20 nm apart) and oriented with the same polarity.
97519	DNA recombinase complex	C	A protein-DNA complex consisting of a higher-order oligomer of strand exchange proteins (recombinases) on single-stranded DNA.
97520	nucleotide-excision repair, preincision complex	C	A multiprotein complex involved in damage recognition, DNA helix unwinding, and endonucleolytic cleavage at the site of DNA damage.
97522	protein-DNA ISRE complex	C	A protein-DNA complex formed through interaction of the protein(s) with an interferon-stimulated response element (ISRE) in the DNA.
97523	transcription ternary complex	C	A protein-DNA-RNA complex composed of RNA polymerase, template DNA, and an RNA transcript.
97524	sperm plasma membrane	C	A plasma membrane that is part of a sperm cell.
97525	spliceosomal snRNP complex	C	A ribonucleoprotein complex involved in formation of the spliceosome and composed of one or more snRNA and multiple protein components.
97526	spliceosomal tri-snRNP complex	C	A spliceosomal snRNP complex containing U4 and U6 (or U4atac and U6atac) snRNAs and U5 snRNAs and associated proteins.
97527	necroptotic signaling pathway	P	A series of molecular signals which triggers the necroptotic death of a cell. The pathway starts with reception of a signal, is characterized by activation of receptor-interacting serine/threonine-protein kinase 1 and/or 3 (RIPK1/3, also called RIP1/3), and ends when the execution phase of necroptosis is triggered.
97528	execution phase of necroptosis	P	A stage of the necroptotic process that starts after a necroptotic signal has been relayed to the execution machinery. Key steps of the execution phase are swelling of organelles, minor ultrastructural modifications of the nucleus (specifically, dilatation of the nuclear membrane and condensation of chromatin into small, irregular, circumscribed patches) and increased cell volume (oncosis), culminating in the disruption of the plasma membrane and subsequent loss of intracellular contents. The execution phase ends when the cell has died.
97529	myeloid leukocyte migration	P	The movement of a myeloid leukocyte within or between different tissues and organs of the body.
97530	granulocyte migration	P	The movement of a granulocyte within or between different tissues and organs of the body.
97531	mast cell migration	P	The movement of a mast cell within or between different tissues and organs of the body.
97532	stress response to acid chemical	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis caused by the chemical structure of the anion portion of a dissociated acid (rather than the acid acting as a proton donor). The acid chemical may be in gaseous, liquid or solid form.
97533	cellular stress response to acid chemical	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in cellular homeostasis caused by the chemical structure of the anion portion of a dissociated acid (rather than the acid acting as a proton donor). The acid chemical may be in gaseous, liquid or solid form.
97534	lymphoid lineage cell migration	P	The orderly movement of a lymphoid lineage cell from one site to another. A lymphoid lineage cell, also called a lymphoid lineage restricted progenitor cell, is a progenitor cell restricted to the lymphoid lineage.
97535	lymphoid lineage cell migration into thymus	P	The movement of a lymphoid lineage cell (also called a lymphoid lineage restricted progenitor cell) into the thymus. Lymphoid lineage cells enter and exit the thymus several times as part of this process.
97536	thymus epithelium morphogenesis	P	The process in which the thymus epithelium is generated and organized.
97537	Y-shaped link	C	A Y-shaped protein complex in the ciliary transition zone that connects the cilium axoneme to the ciliary necklace. Both protein sorting and protein gating occur at this point in the cilium allowing some, but not all proteins to enter the cilium.
97538	ciliary necklace	C	A protein complex located on the cilium membrane in the ciliary transition zone; it is connected to the cilium axoneme via Y-shaped links.
97539	ciliary transition fiber	C	A nine-bladed, propeller-like protein complex that links the distal end of the basal body and the cilium to the plasma membrane. Functions in protein sorting and gating (i.e. active and passive transport of proteins in and out of the cilium).
97540	axonemal central pair	C	Part of the axoneme consisting of the inner two microtubule doublets of the 9+2 axoneme occurring in most motile cilia.
97541	axonemal basal plate	C	Part of the axoneme consisting of a highly electron-dense region at the distal end of the ciliary transition zone within the axonemal lumen at which the axonemal central pair of microtubules is connected to the rest of the axonemal structure.
97542	ciliary tip	C	Part of the cilium where the axoneme ends. The ciliary tip has been implicated in ciliary assembly and disassembly, as well as signal transduction.
97543	ciliary inversin compartment	C	Proximal part of the ciliary shaft to which the inversin protein (also called Inv) specifically localizes. The inversin compartment appears to have a different protein composition than the rest of the cilium, although there is no structure that separates it form the distal part of the cilium.
97544	ciliary shaft	C	The mid part of a cilium between the ciliary base and ciliary tip that extends into the extracellular space.
97545	axonemal outer doublet	C	Part of an axoneme consisting in a doublet microtubule. Nine of these outer doublets form the 9+0 axoneme, while the 9+2 axoneme also contains a central pair. Dynein arms attached to the doublets provide the mechanism of movement of the cilium.
97546	ciliary base	C	Area of the cilium (also called flagellum) where the basal body and the axoneme are anchored to the plasma membrane. The ciliary base encompasses the distal part of the basal body, transition fibers and transition zone and is structurally and functionally very distinct from the rest of the cilium. In this area proteins are sorted and filtered before entering the cilium, and many ciliary proteins localize specifically to this area.
97547	synaptic vesicle protein transport vesicle	C	A cytoplasmic vesicle composed of both tubulovesicular and clear core vesicles that transport synaptic vesicle-associated proteins. Proteins carried by synaptic vesicle protein transport vesicles (STVs) include synaptophysin, synapsin Ia, synaptotagmin and synaptobrevin/vesicle-associated membrane protein 2 (VAMP2). STVs are packaged via the trans-Golgi network before being transported through the axon.
97548	seed abscission	P	The controlled shedding of a seed.
97549	chromatin organization involved in negative regulation of transcription	P	Any process that stops, prevents, or reduces the frequency, rate or extent of transcription by chromatin organization.
97550	transcriptional preinitiation complex	C	A protein-DNA complex composed of proteins binding promoter DNA to form the transcriptional preinitiation complex (PIC), the formation of which is a prerequisite for transcription.
97551	mitochondrial double-strand break repair	P	The repair of double-strand breaks in mitochondrial DNA via homologous and nonhomologous mechanisms to reform a continuous DNA helix.
97552	mitochondrial double-strand break repair via homologous recombination	P	The repair of a double-strand break in mitochondrial DNA in which the broken DNA molecule is repaired using homologous sequences.
97553	calcium ion transmembrane import into cytosol	P	A process in which a calcium ion is transported from one side of a membrane to the other into the cytosol by means of some agent such as a transporter or pore.
97554	left anterior flagellum	C	A cilium (also called flagellum) found in Giardia species (trophozoite stage). It originates at the left anterior basal body, extends laterally through the cytoplasm, crosses the right anterior axoneme, and exits as a membrane-bound flagellum on the anterior left side of the cell.
97555	right anterior flagellum	C	A cilium (also called flagellum) found in Giardia species (trophozoite stage). It originates at the right anterior basal body, extends laterally through the cytoplasm, crosses the left anterior axoneme, and exits as a membrane-bound flagellum on the anterior right side of the cell.
97556	left posteriolateral flagellum	C	A cilium (also called flagellum) found in Giardia species (trophozoite stage). It is nucleated by the left posteriolateral basal body and extends cytoplasmically toward the cell posterior, marking the left anterior boundary of the lateral shield and the left lateral region of the funis before exiting at the left lateral region of the cell body.
97557	right posteriolateral flagellum	C	A cilium (also called flagellum) found in Giardia species (trophozoite stage). It is nucleated by the right posteriolateral basal body and extends cytoplasmically toward the cell posterior, marking the right anterior boundary of the lateral shield and the right lateral region of the funis before exiting at the right lateral region of the cell body.
97558	left ventral flagellum	C	A cilium (also called flagellum) found in Giardia species (trophozoite stage). It is nucleated by the left ventral basal body and exits the cell body proximally and dorsal to the ventral disc.
97559	right ventral flagellum	C	A cilium (also called flagellum) found in Giardia species (trophozoite stage). It is nucleated by the right ventral basal body and exits the cell body proximally and dorsal to the ventral disc.
97560	left caudal flagellum	C	A cilium (also called flagellum) found in Giardia species (trophozoite stage). It is nucleated by the left caudal basal body, extending cytoplasmically and exiting at the posterior end of the cell body.
97561	right caudal flagellum	C	A cilium (also called flagellum) found in Giardia species (trophozoite stage). It is nucleated by the right caudal basal body, extending cytoplasmically and exiting at the posterior end of the cell body.
97562	left lateral basal body pair	C	Set of two basal bodies found in Giardia species (trophozoite stage). It comprises the anterior and ventral basal bodies located to the right of the left nucleus of the trophozoite when viewed dorsally.
97563	left middle basal body pair	C	Set of two basal bodies found in Giardia species (trophozoite stage). It comprises the caudal and posteriolateral basal bodies located to the right of the left nucleus of the trophozoite when viewed dorsally.
97564	right lateral basal body pair	C	Set of two basal bodies found in Giardia species (trophozoite stage). It comprises the anterior and ventral basal bodies located to the left of the right nucleus of the trophozoite when viewed dorsally.
97565	right middle basal body pair	C	Set of two basal bodies found in Giardia species (trophozoite stage). It comprises the caudal and posteriolateral basal bodies located to the left of the right nucleus of the trophozoite when viewed dorsally.
97566	left tetrad	C	Set of four basal bodies found in Giardia species (trophozoite stage). It comprises the left lateral basal body pair and the left middle basal body pair (i.e. the anterior, ventral, caudal and posteriolateral basal bodies located to the right of the left nucleus of the trophozoite when viewed dorsally).
97567	right tetrad	C	Set of four basal bodies found in Giardia species (trophozoite stage). It comprises the right lateral basal body pair and the right middle basal body pair (i.e. the anterior, ventral, caudal and posteriolateral basal bodies located to the left of the right nucleus of the trophozoite when viewed dorsally).
97568	median body	C	A non-membrane bound, semi-organized microtubule array of unknown function found in Giardia species (trophozoite stage). It is located on the dorsal side of the trophozoite, slightly posterior to the ventral disc.
97569	lateral shield	C	Region of the ventral side of the cell body found in Giardia species (trophozoite stage). It is located posterior on either side of the ventral groove; the upper boundary is the ventral disc, and the lower boundary is marked by the posteriolateral flagella.
97570	cyst wall	C	The specialized envelope lying outside the cell membrane of a cyst. A cyst is a resting or dormant stage of a microorganism, usually a bacterium or a protist or rarely an invertebrate animal, that helps the organism to survive in unfavorable environmental conditions. In protists such as protozoan parasites alternating cystic- and non-cystic stages, the cyst wall is usually composed of carbohydrates and proteins.
97571	left nucleus	C	One of the two nuclei found in Giardia species (trophozoite stage). It is located on the left side of the cell when viewed from the dorsal side.
97572	right nucleus	C	One of the two nuclei found in Giardia species (trophozoite stage). It is located on the right side of the cell when viewed from the dorsal side.
97573	glutathione oxidoreductase activity	F	Catalysis of the reaction: protein-S-S-glutathione + glutathione-SH = protein-SH + glutathione-S-S-glutathione.
97574	lateral part of cell	C	The region of a polarized cell other than its tips or ends (in some cell types, one end may be called the apex and the other the base). For example, in a polarized epithelial cell, the lateral part includes the cell sides which interface adjacent cells.
97575	lateral cell cortex	C	The region directly beneath the plasma membrane of the lateral portion of the cell.
97576	vacuole fusion	P	Merging of two or more vacuoles, or of vacuoles and vesicles within a cell to form a single larger vacuole.
97577	sequestering of iron ion	P	The process of binding or confining iron ions such that they are separated from other components of a biological system.
97578	sequestering of copper ion	P	The process of binding or confining copper ions such that they are separated from other components of a biological system.
97579	extracellular sequestering of copper ion	P	The process of binding or confining copper ions in an extracellular area such that they are separated from other components of a biological system.
97580	intracellular sequestering of copper ion	P	The process of binding or confining copper ions in an intracellular area such that they are separated from other components of a biological system.
97581	lamellipodium organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a lamellipodium. A lamellipodium is a thin sheetlike process extended by the leading edge of a crawling fibroblast; contains a dense meshwork of actin filaments.
97582	dolichyl-phosphate-mannose-protein mannosyltransferase Pmt1p-Pmt2p dimer complex	C	A protein dimer complex that possesses dolichyl-phosphate-mannose-protein mannosyltransferase activity and, in S. cerevisiae, is composed of Pmt1p-Pmt2p.
97583	dolichyl-phosphate-mannose-protein mannosyltransferase Pmt1p-Pmt3p dimer complex	C	A protein dimer complex that possesses dolichyl-phosphate-mannose-protein mannosyltransferase activity and, in S. cerevisiae, is composed of Pmt1p-Pmt3p.
97584	dolichyl-phosphate-mannose-protein mannosyltransferase Pmt5p-Pmt2p dimer complex	C	A protein dimer complex that possesses dolichyl-phosphate-mannose-protein mannosyltransferase activity and, in S. cerevisiae, is composed of Pmt5p-Pmt2p.
97585	dolichyl-phosphate-mannose-protein mannosyltransferase Pmt5p-Pmt3p dimer complex	C	A protein dimer complex that possesses dolichyl-phosphate-mannose-protein mannosyltransferase activity and, in S. cerevisiae, is composed of Pmt5p-Pmt3p.
97586	dolichyl-phosphate-mannose-protein mannosyltransferase Pmt4p homodimer complex	C	A protein dimer complex that possesses dolichyl-phosphate-mannose-protein mannosyltransferase activity and, in S. cerevisiae, is composed of Pmt4p.
97587	MutLgamma complex	C	A heterodimer involved in the recognition of base-base and small insertion/deletion mismatches. In S. cerevisiae the complex consists of two subunits, Mlh1 and Mlh3.
97588	archaeal or bacterial-type flagellum-dependent cell motility	P	Cell motility due to movement of bacterial- or archaeal-type flagella.
97589	archaeal-type flagellum	C	A non-membrane-bounded organelle superficially similar to a bacterial-type flagellum; they both consist of filaments extending outside the cell, and rotate to propel the cell, but the archaeal flagella (also called archaella) have a unique structure which lacks a central channel. Similar to bacterial type IV pilins, the archaeal flagellins (archaellins) are made with class 3 signal peptides and they are processed by a type IV prepilin peptidase-like enzyme. The archaellins are typically modified by the addition of N-linked glycans which are necessary for proper assembly and/or function.
97590	archaeal-type flagellum-dependent cell motility	P	Cell motility due to the motion of one or more archaeal-type flagella. An archaeal-type flagellum (also called archaellum) is a non-membrane-bounded organelle superficially similar to a bacterial-type flagellum, but having a different molecular structure and lacking a central channel.
97591	ventral disc lateral crest	C	Fibrillar repetitive structure surrounding the ventral disc edge in Giardia species (trophozoite stage). The composition of the lateral crest is not fully known yet.
97592	ventral disc overlap zone	C	A region of the ventral disc of Giardia species (trophozoite stage) where two portions of the same array of microtubules overlap (the microtubule array makes a complete circle and overlaps on itself).
97593	ventral disc microtubule array	C	A part of the ventral disc of Giardia species (trophozoite stage) consisting of a spiral array of microtubules linked to the ventral membrane. These microtubules form the base of the ventral disc dorsal microribbons that extend nearly perpendicular from the membrane.
97594	ventral disc dorsal microribbon	C	Trilaminar structure extending perpendicularly into the cytoplasm along the length of ventral disc microtubules in Giardia species (trophozoite stage). Constituents of dorsal microribbons (also called dorsal ribbons or microribbons) include alpha-coiled-helix proteins approximately 29 to 38 kDa in size. These proteins line the edges of the microribbons but are not found in microtubules. Tubulins are not found in microribbons.
97595	ventral disc crossbridge	C	Structure horizontally linking adjacent microribbons of the ventral disc in Giardia species (trophozoite stage). The composition of crossbridges is not fully known yet.
97596	ventral disc supernumerary microtubule array	C	A partial left-handed spiral array of microtubules that lies generally dorsal to the main ventral disc microtubule array in Giardia species (trophozoite stage).
97597	ventral disc	C	Specialized organelle found in Giardia species (trophozoite stage) and characterized by a spiral array of microtubules and microtubule-associated structures including dorsal microribbons and crossbridges. The edge of the ventral disc narrows into a lateral crest. The ventral disk mediates mechanical attachment of the trophozoite to the host's intestinal wall, and contains the contractile proteins actinin, alpha-actinin, myosin, and tropomyosin working towards contraction of the disk involved in adherence.
97598	sperm cytoplasmic droplet	C	A small amount of cytoplasm surrounded by a cell membrane that is generally retained in spermatozoa after spermiogenesis, when the majority of the cytoplasm is phagocytosed by Sertoli cells to produce "residual bodies". Initially, the droplet is located at the neck just behind the head of an elongated spermatid. During epididymal transit, the cytoplasmic droplet migrates caudally to the annulus at the end of the midpiece; the exact position and time varies by species. The cytoplasmic droplet consists of lipids, lipoproteins, RNAs, a variety of hydrolytic enzymes, receptors, ion channels, and Golgi-derived vesicles. The droplet may be involved in regulatory volume loss (RVD) at ejaculation, and in most species, though not in humans, the cytoplasmic droplet is lost at ejaculation. Note that the cytoplasmic droplet is distinct from "excessive residual cytoplasm" that sometimes remains in epididymal spermatozoa, particularly when spermiogenesis has been disrupted.
97599	xylanase activity	F	Catalysis of the hydrolysis of xylans, homopolysaccharides composed of xylose residues.
97600	exoxylanase activity	F	A xylanase activity that acts on one of the ends of a xylan polymer which does not contain side chains.
97601	retina blood vessel maintenance	P	A retina homeostatic process preventing the degeneration of a retina blood vessel.
97602	cullin family protein binding	F	Interacting selectively and non-covalently with any member of the cullin family, hydrophobic proteins that act as scaffolds for ubiquitin ligases (E3).
97603	temperature-gated ion channel activity	F	Enables the transmembrane transfer of an ion by a channel that opens in response to a temperature stimulus (e.g. exposure to a temperature range different than the optimal temperature for that organism).
97604	temperature-gated cation channel activity	F	Enables the transmembrane transfer of a cation by a channel that opens in response to a temperature stimulus (e.g. exposure to a temperature range different than the optimal temperature for that organism).
97605	regulation of nuclear envelope permeability	P	Any process that modulates the frequency, rate or extent of the passage or uptake of molecules by the nuclear envelope.
97606	positive regulation of nuclear envelope permeability	P	Any process that increases the frequency, rate or extent of the passage or uptake of molecules by the nuclear envelope.
97607	negative regulation of nuclear envelope permeability	P	Any process that decreases the frequency, rate or extent of the passage or uptake of molecules by the nuclear envelope.
97608	transverse flagellum	C	A motile cilium found in dinoflagellates. It coils around the cell and provides the forward thrust for motility. It is often contained in a furrow called the cingulum, and emerges from a flagellar pore located in the cingulum.
97609	longitudinal flagellum	C	A motile cilium found in dinoflagellates. It trails the cell and acts as a steering rudder. It is often partially contained in a furrow called the sulcus, and emerges from a flagellar pore located in the sulcus.
97610	cell surface furrow	C	A furrow that may be found on the cell surface. Examples are the cleavage furrow observed during cytokinesis in animal cells, and the cingulum and sulcus found in some dinoflagellates.
97611	dinoflagellate cingulum	C	A cell surface furrow that wraps around a dinoflagellate cell; the transverse flagellum lies in it.
97612	dinoflagellate sulcus	C	A cell surface furrow that occurs on the ventral side of a dinoflagellate cell. It partially houses the longitudinal flagellum. The sulcus intersects with the cingulum on the ventral side of a dinoflagellate cell.
97613	dinoflagellate epicone	C	The part of a dinoflagellate cell above the cingulum; also referred to as the anterior portion of a dinoflagellate cell. It is separated from the hypocone by the cingulum.
97614	dinoflagellate hypocone	C	The part of a dinoflagellate cell below the cingulum; also referred to as the posterior portion of a dinoflagellate cell. It is separated from the epicone by the cingulum.
97615	modulation by host of symbiont type IV pilus-dependent motility	P	The process in which an organism effects a change in the type IV pilus-dependent motility of a symbiont organism (i.e. the controlled movement of a bacterial cell which is dependent on the presence of type IV pili, and which includes social gliding motility and twitching motility). The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.
97616	positive regulation by host of symbiont type IV pilus-dependent motility	P	Any process in which an organism activates, maintains or increases the frequency, rate or extent of the type IV pilus-dependent motility of a symbiont organism (i.e. the controlled movement of a bacterial cell which is dependent on the presence of type IV pili, and which includes social gliding motility and twitching motility). The symbiont is defined as the smaller of the organisms involved in a symbiotic interaction.
97617	annealing activity	F	A nucleic acid binding activity that brings together complementary sequences of nucleic acids so that they pair by hydrogen bonds to form a double-stranded polynucleotide.
97618	dinoflagellate sulcal notch	C	A dinoflagellate sulcus that extends all the way to the posterior end of the cell (also known as antapex). The presence of a sulcal notch makes the dinoflagellate hypocone appear bilobed.
97619	PTEX complex	C	A protein complex that acts as a protein trafficking machinery and is responsible for the export of proteins across the parasitophorous (symbiont-containing) vacuolar membrane and into the human host cell. The PTEX complex is located in the vacuole membrane. It is ATP-powered, and comprises heat shock protein 101 (HSP101; a ClpA/B-like ATPase from the AAA+ superfamily, of a type commonly associated with protein translocons), a parasite protein termed PTEX150, and exported protein 2 (EXP2). EXP2 is the potential channel, as it is the membrane-associated component of the core PTEX complex. Two other proteins, PTEX88 and thioredoxin 2 (TRX2), were also identified as PTEX components.
97620	(R)-mandelate dehydrogenase activity	F	Catalysis of the reaction: (R)-2-hydroxy-2-phenylacetate + acceptor = phenylglyoxylate + reduced acceptor.
97621	monoamine oxidase activity	F	Catalysis of the reaction: RCH2NHR' + H2O + O2 = RCHO + R'NH2 + H2O2.
97622	cytoplasmic translational elongation through polyproline stretches	P	The successive addition of amino acid residues to a nascent polypeptide chain, proceeding through regions of multiple repeated proline codons, during protein biosynthesis in the cytoplasm.
97623	potassium ion export across plasma membrane	P	The directed movement of potassium ions from inside of a cell, across the plasma membrane and into the extracellular region.
97624	UDP-galactose transmembrane import into Golgi lumen	P	The directed movement of UDP-galactose into the Golgi lumen across the Golgi membrane.
97625	low-affinity basic amino acid transmembrane transporter activity	F	Catalysis of the transfer of basic amino acids from one side of a membrane to the other. Basic amino acids have a pH above 7. In low-affinity transport the transporter is able to bind the solute only if it is present at very high concentrations.
97626	low-affinity L-arginine transmembrane transporter activity	F	Catalysis of the transfer of L-arginine from one side of a membrane to the other. In low-affinity transport the transporter is able to bind the solute only if it is present at very high concentrations.
97627	high-affinity L-ornithine transmembrane transporter activity	F	Catalysis of the transfer of L-ornithine from one side of a membrane to the other. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.
97628	distal tip cell migration	P	The orderly movement of a distal tip cell.
97629	extrinsic component of omegasome membrane	C	The component of the omegasome membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
97630	intrinsic component of omegasome membrane	C	The component of the omegasome membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.
97631	integral component of omegasome membrane	C	The component of the omegasome membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
97632	extrinsic component of pre-autophagosomal structure membrane	C	The component of the pre-autophagosomal structure membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
97633	intrinsic component of pre-autophagosomal structure membrane	C	The component of the pre-autophagosomal structure membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.
97634	integral component of pre-autophagosomal structure membrane	C	The component of the pre-autophagosomal structure membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
97635	extrinsic component of autophagosome membrane	C	The component of the autophagosome membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
97636	intrinsic component of autophagosome membrane	C	The component of the autophagosome membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.
97637	integral component of autophagosome membrane	C	The component of the autophagosome membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
97638	L-arginine import across plasma membrane	P	The directed movement of L-arginine from outside of a cell, across the plasma membrane and into the cytosol.
97639	L-lysine import across plasma membrane	P	The directed movement of L-lysine from outside of a cell, across the plasma membrane and into the cytosol.
97640	L-ornithine import across plasma membrane	P	The directed movement of L-ornithine from outside of a cell, across the plasma membrane and into the cytosol.
97641	alpha-ketoglutarate-dependent xanthine dioxygenase activity	F	Catalysis of the reaction: 2-oxoglutarate (alpha-ketoglutarate) + O2 + xanthine = CO2 + succinate + urate.
97642	calcitonin family receptor activity	F	Combining with any member of the calcitonin family (e.g. adrenomedullin, adrenomedullin 2 (intermedin), amylin, calcitonin and calcitonin gene-related peptides (CGRPs)) to initiate a change in cell activity.
97643	amylin receptor activity	F	Combining with amylin to initiate a change in cell activity.
97644	calcitonin family binding	F	Interacting selectively and non-covalently with any member of the calcitonin family (e.g. adrenomedullin, adrenomedullin 2 (intermedin), amylin, calcitonin and calcitonin gene-related peptides (CGRPs)).
97645	amylin binding	F	Interacting selectively and non-covalently with amylin.
97646	calcitonin family receptor signaling pathway	P	A series of molecular signals initiated by an extracellular member of the calcitonin family (e.g. adrenomedullin, adrenomedullin 2 (intermedin), amylin, calcitonin and calcitonin gene-related peptides (CGRPs)) combining with a calcitonin family receptor on the surface of the target cell. Calcitonin family receptors may form dimers, trimers or tetramers; adrenomedullin and amylin receptors have only been observed as dimers so far.
97647	amylin receptor signaling pathway	P	A series of molecular signals initiated by an extracellular amylin combining with a dimeric amylin receptor on the surface of the target cell.
97648	G-protein coupled receptor complex	C	A protein complex that contains G-protein coupled receptors.
97649	A axonemal microtubule	C	A complete microtubule with 13 protofilaments that fuses with an incomplete microtubule called B tubule (containing 10 protofilaments only) to form an axonemal outer doublet. Inner and outer dynein arms, as well as the radial spoke, are attached to the A tubule.
97650	B axonemal microtubule	C	An incomplete microtubule containing 10 protofilaments that fuses with a complete microtubule called A tubule (containing 13 protofilaments) to form an axonemal outer doublet.
97651	phosphatidylinositol 3-kinase complex, class I	C	A phosphatidylinositol 3-kinase complex that contains a catalytic and a regulatory subunit of a phosphatidylinositol 3-kinase (PI3K) enzyme, plus one or more adaptor proteins. Class I PI3Ks phosphorylate phosphatidylinositol [PI], phosphatidylinositol-4-phosphate [PI(4)P] and phosphatidylinositol-4,5-bisphosphate [PI(4,5)P2], and are divided into subclasses A and B according to the type of adaptor subunit with which they associate. The class I PI3K subfamily of genes comprises members in vertebrates, worm and fly, but none in yeast.
97652	phosphatidylinositol 3-kinase complex, class II	C	A phosphatidylinositol 3-kinase complex that contains a catalytic subunit of a phosphatidylinositol 3-kinase (PI3K) enzyme and one or more adaptor proteins. There is no known obligatory regulatory subunit. The class II PI3K (PI3KC2) subfamily of genes has members in vertebrates, worm and fly, but none in yeast.
97653	unencapsulated part of cell	C	The part of a cell encompassing the intracellular environment and the plasma membrane; it excludes any external encapsulating structures.
97654	platelet SNARE complex	C	A SNARE complex that is capable of fusing intracellular vesicles to the plasma membrane of platelets for exocytosis of alpha-granules or dense granules. Contains isoforms of VAMP, SNAP and syntaxin proteins. Ternary SNARE complexes interact in a circular array to form ring complexes or channels around the membrane fusion. A common composition in human is VAMP-8, SNAP-23 and syntaxin-2 or -4.
97655	serpin family protein binding	F	Interacting selectively and non-covalently with any member of the serpin protein family (serine protease inhibitors or classified inhibitor family I4). Serpins are a broadly distributed family of protease inhibitors that use a conformational change to inhibit target enzymes. They are central in controlling many important proteolytic cascades. The majority of serpins inhibit serine proteases, but serpins that inhibit caspases and papain-like cysteine proteases have also been identified. Rarely, serpins perform a non-inhibitory function; for example, several human serpins function as hormone transporters and certain serpins function as molecular chaperones or tumor suppressors.
97656	cell-cell self recognition	P	A cell-cell recognition process by which a cell distinguishes between self and non self during cooperative behavior, such as early development.
97657	3',5'-nucleotide bisphosphate phosphatase activity	F	Catalysis of the reaction: 3',5'-nucleotide bisphosphate + H20 = 5'-nucleotide monophosphate + phosphate.
97658	Asi complex	C	A nuclear ubiquitin ligase multiprotein complex located in the inner nuclear membrane (INM) that recognizes and ubiquitinates misfolded INM proteins and also some proteins involved in sterol biosynthesis, during ER-associated protein degradation (ERAD). In S. cerevisiae, this complex contains the ubiquitin ligases Asi1p and Asi3p.
97659	nucleic acid-templated transcription	P	The cellular synthesis of RNA on a template of nucleic acid (DNA or RNA).
97660	SCF-Cdc4 ubiquitin ligase complex	C	An SCF ubiquitin ligase complex in which the F-box protein is Cdc4 in S. cerevisiae.
97661	SCF-Ctf13 ubiquitin ligase complex	C	An SCF ubiquitin ligase complex in which the F-box protein is Ctf13 in S. cerevisiae.
97662	SCF-Das1 ubiquitin ligase complex	C	An SCF ubiquitin ligase complex in which the F-box protein is Das1 in S. cerevisiae.
97663	SCF-Dia2/Pof3 ubiquitin ligase complex	C	An SCF ubiquitin ligase complex in which the F-box protein is Dia2 in S. cerevisiae (Pof3 in S. pombe).
97664	SCF-Grr1/Pof2 ubiquitin ligase complex	C	An SCF ubiquitin ligase complex in which the F-box protein is Grr1 in S. cerevisiae (Pof2 in S. pombe).
97665	SCF-Mdm30 ubiquitin ligase complex	C	An SCF ubiquitin ligase complex in which the F-box protein is Mdm30 in S. cerevisiae.
97666	SCF-Met30/Pof1 ubiquitin ligase complex	C	An SCF ubiquitin ligase complex in which the F-box protein is Met30 in S. cerevisiae (Pof1 in S pombe).
97667	SCF-Rcy1/Pof6 ubiquitin ligase complex	C	An SCF ubiquitin ligase complex in which the F-box protein is Rcy1 in S. cerevisiae (Pof6 in S. pombe).
97668	SCF-Saf1/Pof9 ubiquitin ligase complex	C	An SCF ubiquitin ligase complex in which the F-box protein is Saf1 in S. cerevisiae (Pof9 in S. pombe).
97669	SCF-Skp2 ubiquitin ligase complex	C	An SCF ubiquitin ligase complex in which the F-box protein is Skp2 in S. cerevisiae.
97670	SCF-Ufo1/Pof10 ubiquitin ligase complex	C	An SCF ubiquitin ligase complex in which the F-box protein is Ufo1 in S. cerevisiae (Pof10 in S. pombe).
97671	SCF-YDR131C ubiquitin ligase complex	C	An SCF ubiquitin ligase complex in which the F-box protein is YDR131C in S. cerevisiae.
97672	SCF-Pof5 ubiquitin ligase complex	C	An SCF ubiquitin ligase complex in which the F-box protein is Pof5 in S. pombe (YDR306C in S. cerevisiae).
97673	SCF-Ucc1 ubiquitin ligase complex	C	An SCF ubiquitin ligase complex in which the F-box protein is YLR224W in S. cerevisiae.
97674	SCF-YLR352W ubiquitin ligase complex	C	An SCF ubiquitin ligase complex in which the F-box protein is YLR352W in S. cerevisiae.
97675	SCF-Hrt3/Pof7 ubiquitin ligase complex	C	An SCF ubiquitin ligase complex in which the F-box protein is Hrt3 in S. cerevisiae (Pof7 in S. pombe).
97676	histone H3-K36 dimethylation	P	The modification of histone H3 by addition of two methyl groups to lysine at position 36 of the histone.
97677	STAT family protein binding	F	Interacting selectively and non-covalently with any member of the signal transducers and activators of transcription (STAT) protein family. STATs are, as the name indicates, both signal transducers and transcription factors. STATs are activated by cytokines and some growth factors and thus control important biological processes including cell growth, cell differentiation, apoptosis and immune responses.
97678	SOCS family protein binding	F	Interacting selectively and non-covalently with any member of the suppressor of cytokine signaling (SOCS) family of proteins. SOCS represent an important mechanism to extinguish cytokine and growth factor receptor signaling. Individual SOCS proteins are typically induced by specific cytokines and growth factors, thereby generating a negative feedback loop. SOCS proteins have important functions in development and homeostasis, and in disease, particularly tumor suppression and anti-inflammatory functions.
97679	other organism cytoplasm	C	The cytoplasm of a secondary organism with which the first organism is interacting.
97680	double-strand break repair via classical nonhomologous end joining	P	An instance of double-strand break repair via nonhomologous end joining that requires a number of factors important for V(D)J recombination, including the KU70/80 heterodimer (KU), XRCC4, ligase IV, and DNA-PKcs in mammals. It does not produce translocations (as opposed to the alternative nonhomologous end joining).
97681	double-strand break repair via alternative nonhomologous end joining	P	An instance of double-strand break repair via nonhomologous end joining that is independent of factors important for V(D)J recombination (as opposed to classical nonhomologous end joining). It often results in a deletion with microhomology (i.e. 5-25bp homology) at the repair junction. Among different subclasses of nonhomologous end joining (NHEJ), alternative NHEJ appears to play a significant role in the etiology of mutations that arise during cancer development and treatment.
97682	intracellular phosphatidylinositol-3,5-bisphosphate-sensitive cation channel activity	F	Enables the transmembrane transfer of cations by a channel that opens when phosphatidylinositol-3,5-bisphosphate has been bound by the channel complex or one of its constituent parts.
97683	dinoflagellate apex	C	The anterior most point of a dinoflagellate epicone.
97684	dinoflagellate antapex	C	The anterior most point of a dinoflagellate hypocone.
97685	dinoflagellate apical groove	C	A cell surface furrow (or groove) found on a dinoflagellate apex. It typically loops around the apex.
97686	dinoflagellate apical horn	C	A horn-shaped dinoflagellate apex found in thecate species.
97687	dinoflagellate antapical horn	C	A horn-shaped dinoflagellate antapex found in thecate species.
97688	glutamate receptor clustering	P	The neurotransmitter-gated ion channel clustering process in which glutamate receptors are localized to distinct domains in the cell membrane.
97689	iron channel activity	F	Enables the facilitated diffusion of an iron ion (by an energy-independent process) involving passage through a transmembrane aqueous pore or channel without evidence for a carrier-mediated mechanism.
97690	iron channel inhibitor activity	F	Stops, prevents, or reduces the activity of an iron channel.
97691	bacterial extracellular vesicle	C	Small membrane vesicle (< 1 um) that buds off a prokaryotic cell plasma membrane, able to carry proteins, phospholipids, lipopolysaccharides, nucleic acids, viruses, and more. Important in intercellular communication and pathogenesis; can exist within host cells.
97692	histone H3-K4 monomethylation	P	The modification of histone H3 by addition of one methyl group to lysine at position 4 of the histone.
97693	ocelloid	C	Eye-like subcellular structure found in dinoflagellates (a large group of single-celled eukaryotes). Consists of subcellular analogues to a cornea, lens, iris, and retina. Ocelloids are built from pre-existing organelles, including a cornea-like layer made of mitochondria and a retinal body made of anastomosing plastids.
97694	establishment of RNA localization to telomere	P	The directed movement of RNA to a specific location in the telomeric region of a chromosome.
97695	establishment of macromolecular complex localization to telomere	P	The directed movement of a macromolecular complex to a specific location in the telomeric region of a chromosome.
97696	STAT cascade	P	An intracellular signal transduction process in which STAT proteins (Signal Transducers and Activators of Transcription) convey a signal to trigger a change in the activity or state of a cell. The STAT cascade begins with activation of STAT proteins by kinases, proceeds through dimerization and subsequent nuclear translocation of STAT proteins, and ends with regulation of target gene expression by STAT proteins.
97697	tRNA 5-carboxymethoxyuridine methyltransferase activity	F	Catalysis of the transfer of a methyl group from S-adenosylmethionine to a 5-carboxymethoxy-modified uridine residue in a tRNA molecule.
97698	telomere maintenance via base-excision repair	P	A telomere maintenance process that occurs by base-excision repair of telomeric DNA in response to DNA damage. Telomeric sequences are particularly susceptible to oxidative DNA damage, due to their G-rich nature.
97699	vascular endothelial cell response to fluid shear stress	P	Any response to fluid shear stress in a vascular endothelial cell.
97700	vascular endothelial cell response to laminar fluid shear stress	P	Any response to laminar fluid shear stress in a vascular endothelial cell.
97701	response to pulsatile fluid shear stress	P	Any response to fluid shear stress where the fluid is flowing across a solid surface with periodic variations. For example, the endothelium in straight parts of the artery tree is subjected to pulsatile shear stress with a significant forward direction, which is believed to be an important physiological stimulus enhancing vessel compliance and conferring anti-thrombotic, anti-adhesive, and anti-inflammatory effects.
97702	response to oscillatory fluid shear stress	P	Any response to fluid shear stress where the fluid is moving across a solid surface with an oscillatory flow. Disturbed flow patterns at the arterial bifurcations and curvatures may cause endothelial dysfunction, which initiates atherosclerosis.
97703	cellular response to pulsatile fluid shear stress	P	Any response to pulsatile fluid shear stress that occurs at the level of a cell.
97704	cellular response to oscillatory fluid shear stress	P	Any response to oscillatory fluid shear stress that occurs at the level of a cell.
97705	vascular endothelial cell response to pulsatile fluid shear stress	P	Any response to pulsatile fluid shear stress that occurs in a vascular endothelial cell.
97706	vascular endothelial cell response to oscillatory fluid shear stress	P	Any response to oscillatory fluid shear stress that occurs in a vascular endothelial cell.
97707	ferroptosis	P	A programmed cell death characterized morphologically by the presence of smaller than normal mitochondria with condensed mitochondrial membrane densities, reduction or vanishing of mitochondria crista, and outer mitochondrial membrane rupture. Activation of mitochondrial voltage-dependent anion channels and mitogen-activated protein kinases, upregulation of endoplasmic reticulum stress, and inhibition of cystine/glutamate antiporter are involved in the induction of ferroptosis. This process is characterized by the accumulation of lipid peroxidation products and lethal reactive oxygen species (ROS) derived from iron metabolism. Glutathione peroxidase 4 (GPX4), heat shock protein beta-1, and nuclear factor erythroid 2-related factor 2 function as negative regulators of ferroptosis by limiting ROS production and reducing cellular iron uptake, respectively. In contrast, NADPH oxidase and p53 act as positive regulators of ferroptosis by promotion of ROS production and inhibition of expression of SLC7A11 (a specific light-chain subunit of the cystine/glutamate antiporter), respectively. Misregulated ferroptosis has been implicated in multiple physiological and pathological processes.
97708	intracellular vesicle	C	Any vesicle that is part of the intracellular region.
97709	connective tissue replacement	P	The series of events leading to growth of connective tissue when loss of tissues that are incapable of regeneration occurs, or when fibrinous exudate cannot be adequately cleared.
97710	viral terminase, small subunit	C	The part of the viral terminase complex that acts as a phage DNA-recognition component and regulates the activity of the large subunit. The small subunit usually assembles as a heterooligomer with the large subunit.
97711	ciliary basal body docking	P	The docking of a cytosolic centriole/basal body to the plasma membrane via the ciliary transition fibers. In some species this may happen via an intermediate step, by first docking to the ciliary vesicle via the ciliary transition fibers. The basal body-ciliary vesicle then relocates to the plasma membrane, followed by the ciliary vesicle fusing with the plasma membrane, effectively attaching the basal body to the plasma membrane.
97712	vesicle targeting, trans-Golgi to periciliary membrane compartment	P	The process in which vesicles formed at the trans-Golgi network are directed to the plasma membrane surrounding the base of the cilium, including the ciliary pocket, mediated by molecules at the vesicle membrane and target membrane surfaces.
97713	dolichol-phosphate-mannose synthase regulator activity	F	Binds to and modulates the activity of dolichol-phosphate-mannose synthase.
97714	response to viscosity	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a viscosity stimulus.
97715	cellular response to viscosity	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a viscosity stimulus.
97716	copper ion transport across blood-brain barrier	P	The directed movement of copper (Cu) ions passing through the blood-brain barrier.
97717	copper ion transport across blood-cerebrospinal fluid barrier	P	The directed movement of copper (Cu) ions passing through the blood-cerebrospinal fluid barrier.
97718	disordered domain specific binding	F	Interacting selectively and non-covalently with a disordered domain of a protein.
97719	neural tissue regeneration	P	The regrowth of neural tissue following its loss or destruction.
97720	calcineurin-mediated signaling	P	Any intracellular signal transduction in which the signal is passed on within the cell by activation of a transcription factor as a consequence of dephosphorylation by Ca(2+)-activated calcineurin. The process begins with calcium-dependent activation of the phosphatase calcineurin. Calcineurin is a calcium- and calmodulin-dependent serine/threonine protein phosphatase with a conserved function in eukaryotic species from yeast to humans. In yeast and fungi, calcineurin regulates stress signaling and cell cycle, and sporulation and virulence in pathogenic fungi. In metazoans, calcineurin is involved in cell commitment, organogenesis and organ development and immune function of T-lymphocytes. By a conserved mechanism, calcineurin phosphatase activates fungal Crz1 and mammalian NFATc by dephosphorylation and translocation of these transcription factors to the nucleus to regulate gene expression.
97721	ciliary vesicle	C	A Golgi-derived vesicle to which the ciliary basal body docks via its transitional fibers. Its membrane is compositionally distinct from Golgi membranes, and will become the ciliary membrane once the ciliary vesicle is fused to the plasma membrane. The ciliary vesicle is thought to be formed by multiple smaller vesicles that attach to the transitional fibers and then fuse to form a larger vesicle.
97722	sperm motility	P	Any process involved in the controlled movement of a sperm cell.
97723	amoeboid sperm motility	P	Any process involved in the controlled movement of an amoeboid sperm cell.
97724	sperm flagellum movement	P	The directed, self-propelled movement of a sperm flagellum.
97725	histone H3-K79 dimethylation	P	The modification of histone H3 by addition of two methyl groups to lysine at position 79 of the histone.
97726	LEM domain binding	F	Interacting selectively and non-covalently with a LEM domain. The LEM domain (for lamina-associated polypeptide, emerin, MAN1 domain) is present in a group of nuclear proteins that bind chromatin through interaction of the LEM motif with the conserved DNA crosslinking protein, barrier-to-autointegration factor (BAF).
97727	blepharoplast	C	An intracellular non-membrane-bounded organelle found in multi-ciliated sperm cells of some primitive land plants, and consisting of many radially arranged ninefold symmetric cylinders. The blepharoplast is involved in de novo formation of multiple centrioles; it enlarges and then disintegrates into many procentrioles, which elongate and ultimately nucleate cilia on the surface of the sperm cell.
97728	9+0 motile cilium	C	A motile cilium where the axoneme has a ring of nine outer microtubule doublets but no central microtubules (and is therefore called a 9+0 axoneme).
97729	9+2 motile cilium	C	A motile cilium where the axoneme has a ring of nine outer microtubule doublets plus two central microtubules (and is therefore called a 9+2 axoneme).
97730	non-motile cilium	C	A cilium which may have a variable array of axonemal microtubules but does not contain molecular motors.
97731	9+0 non-motile cilium	C	A non-motile cilium where the axoneme has a ring of nine outer microtubule doublets but no central microtubules (and is therefore called a 9+0 axoneme).
97732	9+2 non-motile cilium	C	A non-motile cilium where the axoneme has a ring of nine outer microtubule doublets plus two central microtubules (and is therefore called a 9+2 axoneme).
97733	photoreceptor cell cilium	C	A specialised 9+0 non-motile cilium found in photoreceptor cells. A ciliary transition zone called 'photoreceptor connecting cilium' links the photoreceptor outer segment to the inner segment.
97734	extracellular exosome biogenesis	P	The assembly and secretion of an extracellular exosome, a membrane-bounded vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane.
97735	DIM/DIP cell wall layer	C	A section of the Actinobacterium-type cell wall composed of (phenyl)phthiocerol, phthiodiolone, phthiotriol dimycocerosate, diphthioceranate and other compounds.
97736	aerial mycelium formation	P	The process by which hyphae grow in an upward or outward direction from the surface of the substrate; from there, propagative spores develop in or on characteristic structures that are distinctive of some fungal and bacterial species. The species that form an aerial mycelium develop conidiophores at the ends of the aerial hyphae.
97737	acquisition of mycelium reproductive competence	P	A maturation process by which an organism acquires the ability to reproduce. In fungi, reproductive competence only occurs in a population of filamentous cells that form a mycelium.
97738	substrate mycelium formation	P	The process by which, in some fungal species, hyphae grow as a network of invasive thread-like filaments formed from chains of attached cells within a solid or semi-solid substrate.
97739	negative regulation of ferrichrome biosynthetic process in response to iron	P	Any process that stops, prevents or reduces the rate of ferrichrome biosynthetic process in response to an iron stimulus.
97740	paraflagellar rod	C	A large lattice-like axial structure found in some flagellated protists which extends alongside the axoneme. Protein components of the paraflagellar rod are likely implicated, among other, in adenine nucleotide signalling and metabolism, and in calcium signalling.
97741	mastigoneme	C	A hair-like structure covering the flagella found in some algae (heterokonts and cryptophytes). It is approximately 15 nm in diameter, and usually consist of a tubular shaft that itself terminates in smaller hairs. It is composed of glycoproteins and, likely, carbohydrates. Mastigonemes may assist in locomotion by increasing the surface area of a flagellum.
97742	de novo centriole assembly	P	Centriole assembly in which a centriole arises de novo, rather than by replication from an existing centriole. This process may occur via different mechanisms. Examples include the deuterosome pathway in multicilated epithelial animal cells and formation of centrioles during parthenogenesis in some insects.
97743	de novo centriole assembly via blepharoplast	P	A de novo centriole assembly process observed in multi-ciliated sperm cells of some primitive land plants, and where centrioles are formed from a blepharoplast, ultimately giving rise to multiple cilia on the sperm surface.
97744	urate salt excretion	P	The elimination by an organism of urate salt or uric acid.
97745	mitochondrial tRNA 5'-end processing	P	The process in which the 5' end of a pre-tRNA molecule is converted to that of a mature tRNA in the mitochondrion.
97746	regulation of blood vessel diameter	P	Any process that modulates the diameter of blood vessels.
97747	RNA polymerase activity	F	Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1); the synthesis of RNA from ribonucleotide triphosphates in the presence of a nucleic acid template.
97748	3'-5' RNA polymerase activity	F	Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1); the synthesis of RNA from ribonucleotide triphosphates in the presence of a nucleic acid template, via extension of the 5'-end.
97749	membrane tubulation	P	A membrane organization process resulting in the formation of a tubular projection. This may face inwardly (as in tubular membrane invaginations) or outwardly (as in endosomal tubules).
97750	endosome membrane tubulation	P	A membrane tubulation process occurring in an endosome membrane.
97751	spore-bearing structure formation	P	The process of generating a spore-bearing structure. A spore-bearing structure is an anatomical structure that produces new spores.
98001	receptor-mediated bacteriophage reversible attachment to host cell	P	Process by which a bacteriophage, using its tail fibers, spikes or a baseplate component, initially recognizes and binds to its specific receptor on the host cell surface. This process is reversible and allows the release of a bacteriophage without affecting infection.
98002	receptor-mediated bacteriophage irreversible attachment to host cell	P	The processes by which a bacteriophage initially commits to infection by binding the host receptor irreversibly. Disruption of the phage:cell complex at this step results in the loss of infective phage virions since the process is characterized by conformational changes of bacteriophage head and tail proteins and injection of bacteriophage proteins into the infected cell.
98003	viral tail assembly	P	The aggregation, arrangement and bonding together of a set of components to form a virus tail.
98004	virus tail fiber assembly	P	The aggregation, arrangement and bonding together of a set of components to form a virus tail fiber.
98005	viral head-tail joining	P	Process by which virus heads and tails are attached to each other.
98006	viral DNA genome packaging, headful	P	The encapsulation of the viral genome within the capsid where DNA is packaged into the capsid until the capsid is full.
98009	viral terminase, large subunit	C	The part of the viral terminase complex that contains the translocase and endonuclease activities and allows the translocation of the phage DNA into the procapsid. The large subunit usually assembles as a heterooligomer with the small subunit.
98015	virus tail	C	Part of the virion that may be used to recognize, attach and inject the viral genome and accessory proteins into the host cell.
98017	viral capsid, major subunit	C	The part of the viral capsid that comprises the most common capsomere type. For example, in a T=3 icosahedral capsid, which is composed of 12 pentameric and 20 hexameric capsomeres, the hexameric capsomeres are major subunits.
98018	viral capsid, minor subunit	C	The part of the viral capsid that comprises the less common capsomere type. For example, in a T=3 icosahedral capsid, which is composed of 12 pentameric and 20 hexameric capsomeres, the pentameric capsomeres are minor subunits.
98019	virus tail, major subunit	C	The part of the viral tail that comprises the most common subunit type.
98020	virus tail, minor subunit	C	The part of the viral tail that comprises the least common subunit type.
98021	viral capsid, decoration	C	Component of the virus capsid (head), located on the outer head surface. Involved in the stabilization of the head structure and usually non-essential.
98022	viral capsid, fiber	C	A type of capsid decoration composed of fiber structures.
98023	virus tail, tip	C	The basal end of the virus tail, which is used by the virus to attach to the host cell.
98024	virus tail, fiber	C	The fibrous region of the virus tail used to scan, recognize and attach to the host cell.
98025	virus tail, baseplate	C	Multiprotein component at the distal (head) end of the virus tail to which fibers of tailed viruses may be attached.
98026	virus tail, tube	C	The internal tube of the contractile tails of some viruses. The virus tail tube is the channel for DNA ejection into the host cytoplasm.
98027	virus tail, sheath	C	The external contractile envelope of the tail of some viruses. Its contraction ensures ejection of the virus DNA into the host cytoplasm.
98028	virus tail, shaft	C	The tube of the non-contractile tails of some viruses.
98029	icosahedral viral capsid, spike	C	A short structure attached to an icosahedral virion capsid, and used for attachment to the host cell.
98030	icosahedral viral capsid, neck	C	A region of constriction located below the head and above the tail sheath of viruses with contractile tails (Myoviridae).
98031	icosahedral viral capsid, collar	C	A small disk located at the base of some icosahedral virus capsids.
98032	icosahedral viral capsid, collar fiber	C	A fiber attached to the collar structure of some icosahedral viral capsids.
98033	icosahedral viral capsid, neck fiber	C	A fiber attached to the neck at the base of some icosahedral viral capsids.
98035	viral DNA genome packaging via site-specific sequence recognition	P	The encapsulation of the viral DNA genome within the capsid, which proceeds via cleavage of the viral DNA at specific sites by a viral terminase.
98036	viral DNA genome packaging, 3' extended cos packaging	P	The encapsulation of the viral DNA genome within the capsid, which proceeds via cleavage of the viral DNA at specific sites to produce 3' protruding ends.
98037	viral DNA genome packaging, 5' extended cos packaging	P	The encapsulation of the viral DNA genome within the capsid, which proceeds via cleavage of the viral DNA at specific sites to produce 5' protruding ends.
98038	non-replicative transposition, DNA-mediated	P	Process by which a transposable element is excised from the donor site and integrated at the target site without replication of the element. Also referred to as cut-and-paste transposition.
98039	replicative transposition, DNA-mediated	P	Process of transposition in which the existing element is replicated and one of the copies is excised and integrated at a new target site. Also referred to as copy-and-paste transposition.
98045	virus baseplate assembly	P	The aggregation, arrangement and bonding together of a set of components to form a virus baseplate.
98046	type V protein secretion system complex	C	A complex of proteins that permits the translocation of proteins across the outer membrane via a transmembrane pore, formed by a beta-barrel, into the extracellular milieu or directly into host cells; the secreted proteins contain all the information required for translocation of an effector molecule through the cell envelope. The type V secretion systems includes the autotransporters (type Va), the two-partner secretion system (type Vb) and the Oca family (type Vc).
98061	viral capsid, internal space	C	The region of a virus contained within the capsid shell, and usually containing the viral genome and accessory proteins.
98501	polynucleotide dephosphorylation	P	The process of removing one or more phosphate groups from a polynucleotide.
98502	DNA dephosphorylation	P	The process of removing one or more phosphate groups from a DNA molecule.
98503	DNA 3' dephosphorylation	P	The process of removing a 3' phosphate group from a DNA molecule.
98504	DNA 3' dephosphorylation involved in DNA repair	P	Any 3' DNA dephosphorylation that is involved in the process of DNA repair.
98505	G-rich strand telomeric DNA binding	F	Interacting selectively and non-covalently with G-rich, single-stranded, telomere-associated DNA.
98506	polynucleotide 3' dephosphorylation	P	The process of removing one or more phosphate groups from the 3' end of a polynucleotide.
98507	polynucleotide 5' dephosphorylation	P	The process of removing one or more phosphate groups from the 5' end of a polynucleotide.
98508	endothelial to hematopoietic transition	P	The generation of hematopoietic stem cells from hemogenic endothelial cells by a process that includes tight-junction dissolution and loss of cell polarity followed by delamination from the endothelium.
98509	sensory perception of humidity	P	The series of events required for an organism to detect some level of humidity in its environment, convert this detection into a molecular signal, and recognize and characterize the signal. This is a neurological process.
98510	sensory perception of high humidity	P	The series of events required for an organism to detect high environmental humidity, convert this detection into a molecular signal, and recognize and characterize the signal. This is a neurological process.
98511	sensory perception of low humidity	P	The series of events required for an organism to detect low environmental humidity, convert this detection into a molecular signal, and recognize and characterize the signal. This is a neurological process.
98512	detection of humidity stimulus involved in sensory perception	P	The series of events in which a humidity stimulus is received and converted into a molecular signal as part of the sensory perception of humidity.
98513	detection of humidity	P	The series of events in which a humidity stimulus is received and converted into a molecular signal.
98514	detection of high humidity stimulus involved in sensory perception	P	The series of events in which a high humidity stimulus is detected and converted into a molecular signal as a part of the sensory detection of high humidity.
98515	detection of low humidity stimulus involved in sensory perception	P	The series of events in which a low humidity stimulus is detected and converted into a molecular signal as a part of the sensory detection of low humidity.
98516	detection of high humidity	P	The series of events in which high humidity is detected and converted into a molecular signal.
98517	detection of low humidity	P	The series of events in which low humidity is detected and converted into a molecular signal.
98518	polynucleotide phosphatase activity	F	Catalysis of the reaction: phosphopolynucleotide + H2O = polynucleotide + phosphate.
98519	nucleotide phosphatase activity, acting on free nucleotides	F	Catalysis of the reaction: nucleotide + H2O = nucleotide + phosphate.
98520	excitatory neuromuscular junction	C	The junction between the axon of a motor neuron and a muscle fiber. In response to the arrival of action potentials, the presynaptic button releases molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane of the muscle fiber, leading to a post-synaptic potential responsible for muscle contraction.
98521	inhibitory neuromuscular junction	C	The junction between the axon of a motor neuron and a muscle fiber. In response to the arrival of action potentials, the presynaptic button releases molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane of the muscle fiber, leading to a change in post-synaptic potential that inhibits muscle contraction.
98522	neuromuscular junction of skeletal muscle fiber	C	A neuromuscular junction in which the target muscle cell is a skeletal muscle fiber.
98523	neuromuscular junction of myotube	C	A neuromuscular junction in which the target muscle cell is a myotube.
98524	neuromuscular junction of somatic muscle myotube	C	A neuromuscular junction in which the target muscle cell is a somatic muscle myotube, such as an arthropod somatic muscle cell.
98525	excitatory neuromuscular junction of somatic myotube	C	A neuromuscular junction that functions in the excitation of somatic muscle myotubes, such as an arthropod somatic muscle cells.
98526	inhibitory neuromuscular junction of somatic myotube	C	A neuromuscular junction that functions in the inhibition of somatic muscle myotube contraction. Examples of somatic muscle myotubes include the somatic muscle cells of arthropods.
98527	neuromuscular junction of somatic muscle	C	A neuromuscular junction in which the target muscle cell is a somatic muscle cell, such as those found in nematodes and arthropods.
98528	skeletal muscle fiber differentiation	P	The process in which a relatively unspecialized cell acquires specialized features of a skeletal muscle fiber cell. Skeletal muscle fiber differentiation starts with myoblast fusion and the appearance of specific cell markers (this is the cell development step). Then individual skeletal muscle fibers fuse to form bigger myotubes and start to contract.
98529	neuromuscular junction development, skeletal muscle fiber	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a neuromuscular junction that targets a skeletal muscle fiber.
98530	positive regulation of strand invasion	P	Any process that increases the rate, frequency or extent of strand invasion. Strand invasion is the process in which the nucleoprotein complex (composed of the broken single-strand DNA and the recombinase) searches and identifies a region of homology in intact duplex DNA. The broken single-strand DNA displaces the like strand and forms Watson-Crick base pairs with its complement, forming a duplex in which each strand is from one of the two recombining DNA molecules.
98531	transcription factor activity, direct ligand regulated sequence-specific DNA binding	F	A DNA binding transcription factor activity that is directly regulated by binding of a ligand to the protein with this activity. Examples include the lac and trp repressors in E.coli and many steroid hormone receptors.
98532	histone H3-K27 trimethylation	P	The modification of histone H3 by addition of three methyl groups to lysine at position 27 of the histone.
98533	ATPase dependent transmembrane transport complex	C	A transmembrane protein complex that functions in ATPase dependent active transport across a membrane.
98534	centriole assembly	P	A cellular process that results in the assembly of one or more centrioles.
98535	de novo centriole assembly involved in multi-ciliated epithelial cell differentiation	P	Centriole assembly in which a centriole arises de novo by a process involving an electron-dense structure known as a deuterosome, rather than by duplication of an existing centriole, and occurring as part of multi-ciliated epithelial cell differentiation.
98536	deuterosome	C	A spherical, electron dense, cytoplasmic structure that is involved in de novo assembly of centrioles.
98537	lobed nucleus	C	Nucleus with two or more lobes connected by a thin filament that contains no internal chromatin. Examples include the nuclei of mature basophils, eosinophils and neutrophils in mice and humans.
98538	lumenal side of transport vesicle membrane	C	The side (leaflet) of the transport vesicle membrane that faces the lumen.
98539	cytoplasmic side of transport vesicle membrane	C	The side (leaflet) of the transport vesicle membrane that faces the cytoplasm.
98540	lumenal side of trans-Golgi network transport vesicle membrane	C	The side (leaflet) of the trans-Golgi network transport vesicle membrane that faces the lumen.
98541	cytoplasmic side of trans-Golgi network transport vesicle membrane	C	The side (leaflet) of the trans-Golgi network transport vesicle membrane that faces the cytoplasm.
98542	defense response to other organism	P	Reactions triggered in response to the presence of another organism that act to protect the cell or organism from damage caused by that organism.
98543	detection of other organism	P	The series of events in which a stimulus from another organism is received and converted into a molecular signal.
98544	maintenance of protein complex location	P	Any process in which a protein complex is maintained in a location and prevented from moving elsewhere. These include sequestration, stabilization to prevent transport elsewhere and the active retrieval of protein complexes that move away.
98545	maintenance of protein complex location in cytoplasm	P	Any process in which a protein complex is maintained in a specific location within the cytoplasm and is prevented from moving elsewhere.
98546	2',5-3',5'-cyclic GMP-AMP binding	F	Interacting selectively and non-covalently with c[G(2',5')pA(2',5')p], a cyclic purine dinucleotide that consists of AMP and GMP units cyclized via 2',5' and 3',5' linkages.
98547	lumenal side of Golgi membrane	C	The side of the Golgi membrane that faces the lumen.
98548	cytoplasmic side of Golgi membrane	C	The side (leaflet) of the Golgi membrane that faces the cytoplasm.
98549	somatic ring canal	C	A stable intercellular bridge between somatic cells. Examples include the intercellular bridges between ovarian follicle cells in insects and between imaginal disc cells in insects.
98550	lumenal side of early endosome membrane	C	The side (leaflet) of the early endosome membrane that faces the lumen.
98551	lumenal side of late endosome membrane	C	The side (leaflet) of the late endosome membrane that faces the lumen.
98552	side of membrane	C	A cellular component consisting of one leaflet of a membrane bilayer and any proteins embedded or anchored in it or attached to its surface.
98553	lumenal side of endoplasmic reticulum membrane	C	The side (leaflet) of the plasma membrane that faces the lumen.
98554	cytoplasmic side of endoplasmic reticulum membrane	C	The side (leaflet) of the plasma membrane that faces the cytoplasm.
98555	lumenal side of rough endoplasmic reticulum membrane	C	The side (leaflet) of the rough endoplasmic reticulum membrane that faces the lumen.
98556	cytoplasmic side of rough endoplasmic reticulum membrane	C	The side (leaflet) of the rough endoplasmic reticulum membrane that faces the cytoplasm.
98557	cytoplasmic side of smooth endoplasmic reticulum membrane	C	The side (leaflet) of the smooth endoplasmic reticulum membrane that faces the cytoplasm.
98558	lumenal side of smooth endoplasmic reticulum membrane	C	The side (leaflet) of the smooth endoplasmic reticulum membrane that faces the lumen.
98559	cytoplasmic side of early endosome membrane	C	The side (leaflet) of the early endosome membrane that faces the cytoplasm.
98560	cytoplasmic side of late endosome membrane	C	The side (leaflet) of the late endosome membrane that faces the cytoplasm.
98561	methyl accepting chemotaxis protein complex	C	A transmembrane protein complex that consists of multiple methyl-accepting chemoreceptor protein subunits, a histidine kinase and a connector protein and which functions in the regulation of flagellar rotary motor activity in response to an external chemical stimulus.
98562	cytoplasmic side of membrane	C	The side of a membrane that faces the cytoplasm.
98563	intrinsic component of synaptic vesicle membrane	C	The component of the synaptic vesicle membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.
98564	trans-Golgi network transport vesicle lumen	C	The volume enclosed within the membrane of a trans-Golgi network transport vesicle.
98565	lumenal side of endosome membrane	C	The side (leaflet) of the endosome membrane that faces the lumen.
98566	transport vesicle lumen	C	The volume enclosed within the membrane of a transport vesicle.
98567	periplasmic side of plasma membrane	C	The side (leaflet) of a plasma membrane that faces the periplasm, and all proteins embedded in it or attached to its surface.
98568	external side of mycolate outer membrane	C	The side (leaflet) of the mycolate outer membrane that faces the environment and any proteins embedded in it or loosely bound to its surface.
98569	internal side of mycolate outer membrane	C	The side of the mycolate outer membrane that faces the cell wall peptidoglycan. It is rich in long-chain mycolic acids (hydroxylated branched-chain fatty acids) that are covalently linked to the cell wall peptidoglycan via an arabinogalactan network.
98570	stromal side of plastid inner membrane	C	The side (leaflet) of the plastid inner membrane that faces the stroma, and any proteins embedded in it or loosely bound to its surface.
98571	lumenal side of plastid thylakoid membrane	C	The side (leaflet) of the plastid thylakoid membrane that faces the lumen, and any proteins embedded in it or loosely bound to its surface.
98572	stromal side of plastid thylakoid membrane	C	The side (leaflet) of the plastid thylakoid membrane that faces the stroma, and any proteins embedded in it or loosely bound to its surface.
98573	intrinsic component of mitochondrial membrane	C	The component of the mitochondrial membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.
98574	cytoplasmic side of lysosomal membrane	C	The side (leaflet) of the lysosomal membrane that faces the cytoplasm.
98575	lumenal side of lysosomal membrane	C	The side (leaflet) of the lysosomal membrane that faces the lumen.
98576	lumenal side of membrane	C	Any side (leaflet) of a membrane that faces the lumen of an organelle.
98577	inactive sex chromosome	C	A sex chromosome that has been inactivated.
98578	condensed chromatin of inactivated sex chromosome	C	A condensed form of chromatin that is associated with an inactivated sex chromosome and which is responsible for its inactivation.
98579	active sex chromosome	C	A sex chromosome that has not been inactivated.
98580	chromatin of active sex chromosome	C	Chromatin that is part of an active sex chromosome.
98581	detection of external biotic stimulus	P	The series of events in which an external biotic stimulus is detected and converted into a molecular signal. An external biotic stimulus is defined as one caused or produced by a living organism other than the one being stimulated.
98582	innate vocalization behavior	P	A vocalisation behavior that is innate, i.e. that does not need to be learned in order to occur.
98583	learned vocalization behavior	P	A vocalization behavior that is the result of learning.
98584	host cell synaptic vesicle	C	A secretory organelle of a host cell, some 50 nm in diameter, of presynaptic nerve terminals; accumulates in high concentrations of neurotransmitters and secretes these into the synaptic cleft by fusion with the 'active zone' of the presynaptic plasma membrane.
98585	host cell synaptic vesicle membrane	C	The lipid bilayer surrounding a host synaptic vesicle.
98586	cellular response to virus	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a virus.
98588	bounding membrane of organelle	C	The lipid bilayer that forms the outer-most layer of an organelle.
98589	membrane region	C	A membrane that is a part of a larger membrane. Examples include the apical region of the plasma membrane of an epithelial cell and the various regions of the endoplasmic reticulum membrane.
98590	plasma membrane region	C	A membrane that is a (regional) part of the plasma membrane.
98591	external side of apical plasma membrane	C	The leaflet the apical region of the plasma membrane that faces away from the cytoplasm and any proteins embedded or anchored in it or attached to its surface.
98592	cytoplasmic side of apical plasma membrane	C	The side (leaflet) of the apical region of the plasma membrane that faces the cytoplasm.
98593	goblet cell theca	C	A cup shaped specialization of the cytoskeleton that forms a thin layer located just below the apical mass of mature mucin secretory granules in the cytoplasm of goblet cells of the intestinal epithelium. It consists of an orderly network of intermediate filaments and microtubules. Microtubules are arranged vertically, like barrel staves, along the inner aspect of the theta. Intermediate filaments form two networks: an inner, basketlike network and an outer series of circumferential bundles resembling the hoops of a barrel.
98594	mucin granule	C	A secretory granule that contains mucin.
98595	perivitelline space	C	The space between the membrane of an oocyte and a surrounding membranous structure (zona pellucida or perivitelline membrane).
98596	imitative learning	P	Learning in which new behaviors are acquired through imitation.
98597	observational learning	P	Learning that occurs through observing the behavior of others.
98598	learned vocalization behavior or vocal learning	P	Vocalisation behavior that is the result of learning, or the process by which new vocalizations are learned.
98599	palmitoyl hydrolase activity	F	Catalysis of a hydrolase reaction that removes a palmitoyl moiety from some substrate.
98600	selenomethionine gamma-lyase activity	F	Catalysis of the reaction: L-Selenomethionine + H2O => Methaneselenol + Ammonia + 2-oxobutanoic acid.
98601	selenomethionine adenosyltransferase activity	F	Catalysis of the reaction: ATP + L-Selenomethionine + H2O => Orthophosphate + Diphosphate + Se-Adenosylselenomethionine.
98602	single organism cell adhesion	P	The attachment, via cell adhesion molecules, of a cell to either another cell of the same organism, or to an underlying substrate of the same organism such as the extracellular matrix.
98603	selenol Se-methyltransferase activity	F	Catalysis of the reaction: R + Se-Adenosylselenomethionine => CH3-R + Se-Adenosyl-L-selenohomocysteine.
98604	adenosylselenohomocysteinase activity	F	Catalysis of the reaction: Se-Adenosyl-L-selenohomocysteine + H2O => Adenosine + Selenohomocysteine.
98605	selenocystathionine beta-synthase activity	F	Catalysis of the reaction: L-Serine + Selenohomocysteine => L-Selenocystathionine + H2O.
98606	selenocystathionine gamma-lyase activity	F	Catalysis of the reaction: L-Selenocystathionine + H2O => L-Selenocysteine + NH3 + 2-Oxobutanoic acid.
98607	methylselenocysteine deselenhydrase activity	F	Catalysis of the reaction: Se-Methyl-L-selenocysteine + H2O => pyruvic acid + NH3 + Methaneselenol.
98608	methylselenol demethylase activity	F	Catalysis of the reaction: methylselenol + H2O => H2Se + CH3OH.
98609	cell-cell adhesion	P	The attachment of one cell to another cell via adhesion molecules.
98610	adhesion between unicellular organisms	P	The attachment of two unicellular organisms to each other.
98611	cell-cell adhesion involved in galactose-specific flocculation	P	Cell-cell adhesion between two single-celled organisms, during flocculation, mediated via the binding of cell wall proteins on one cell to galactose residues on the other.
98612	cell-cell adhesion involved in mannose-specific flocculation	P	Cell-cell adhesion between two single-celled organisms, during flocculation, mediated via the binding of cell wall proteins on one cell to mannose residues on the other.
98613	methaneselenol methyltransferase activity	F	Catalysis of the reaction: S-Adenosyl-L-methionine + Methaneselenol => S-Adenosyl-L-homocysteine + Dimethyl selenide.
98614	hydrogen selenide methyltransferase activity	F	Catalysis of the reaction: S-Adenosyl-L-methionine + Hydrogen selenide => S-Adenosyl-L-homocysteine + Methaneselenol.
98615	dimethyl selenide methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + dimethyl selenide => S-adenosyl-L-homocysteine + trimethylselenonium.
98616	selenate adenylyltransferase (ATP) activity	F	Catalysis of the reaction: ATP + H2SeO4 => Diphosphate + Adenylylselenate.
98617	adenylylselenate kinase activity	F	Catalysis of the reaction: ATP + Adenylylselenate => ADP + 3'-Phosphoadenylylselenate.
98618	selenomethionine-tRNA ligase activity	F	Catalysis of the reaction: ATP + L-Selenomethionine + tRNA(Met) => AMP + Diphosphate + Selenomethionyl-tRNA(Met).
98619	selenocysteine-tRNA ligase activity	F	Catalysis of the reaction: tRNASec + L-Ser + ATP ---> Ser-tRNASec + AMP + Diphosphate.
98620	seryl-selenocysteinyl-tRNA kinase activity	F	Catalysis of the reaction: Ser-tRNA(Sec) + ATP ---> Sep-tRNA(Sec) + ADP
98621	phosphoseryl-selenocysteinyl-tRNA selenium transferase activity	F	Catalysis of the reaction: O-Phosphoseryl-tRNA(Sec) + Selenophosphoric acid + H2O => L-Selenocysteinyl-tRNA(Sec) + 2 phosphoric acid.
98622	selenodiglutathione-disulfide reductase activity	F	Catalysis of the reaction: H+ + selenodiglutathione + NADPH => gluthathioselenol + glutathione + NADP+.
98623	selenite reductase activity	F	Catalysis of the reaction: SeO3(2-) + 3NADPH + 5H+ ---> H2Se + 3NADP+ + 3H2O.
98624	3'-Phosphoadenylylselenate reductase activity	F	Catalysis of the reaction: 3'-Phosphoadenylylselenate + NADPH => Adenosine 3',5'-bisphosphate + Selenite + NADP+ + H+.
98625	methylselenol reductase activity	F	Catalysis of the reaction: NADPH + H+ + CH3SeOH => NADP+ + CH3SeH + H2O
98626	methylseleninic acid reductase activity	F	Catalysis of the reaction: NADPH + H+ + CH3SeO2H => NADP+ + CH3SeOH + H2O.
98627	protein arginine phosphatase activity	F	Catalysis of the reaction: protein arginine phosphate + H2O = protein arginine + phosphate.
98628	peptidyl-N-phospho-arginine dephosphorylation	P	The removal of phosphate residues from peptidyl-N-phospho-arginine to form peptidyl-arginine
98629	trans-Golgi network membrane organization	P	A process which results in the assembly, arrangement of constituent parts, or disassembly of a trans-Golgi network membrane.
98630	aggregation of unicellular organisms	P	The clustering together of unicellular organisms in suspension form aggregates.
98631	protein binding involved in cell adhesion	F	Any protein binding that is involved in cell adhesion.
98632	protein binding involved in cell-cell adhesion	F	Any protein binding that is involved in cell-cell adhesion.
98633	collagen fibril binding	F	Interacting selectively and non-covalently with a collagen fibril.
98634	protein binding involved in cell-matrix adhesion	F	Any protein binding that is involved in cell-matrix adhesion.
98635	protein complex involved in cell-cell adhesion	C	Any protein complex that is capable of carrying out some part of the process of cell-cell adhesion.
98636	protein complex involved in cell adhesion	C	Any protein complex that is capable of carrying out some part of the process of cell adhesion to the cell matrix or to another cell.
98637	protein complex involved in cell-matrix adhesion	C	Any protein complex that is capable of carrying out some part of the process of cell-matrix adhesion.
98638	laminin binding involved in cell-matrix adhesion	F	Any laminin protein binding that occurs as part of cell-matrix adhesion.
98639	collagen binding involved in cell-matrix adhesion	F	Any collagen binding that occurs as part of cell-matrix adhesion.
98640	integrin binding involved in cell-matrix adhesion	F	Any integrin binding that occurs as part of the process of cell-matrix adhesion.
98641	cadherin binding involved in cell-cell adhesion	F	Any cadherin binding that occurs as part of the process of cell-cell adhesion.
98642	network-forming collagen trimer	C	A collagen trimer that forms networks.
98643	banded collagen fibril	C	A supramolecular assembly of fibrillar collagen complexes in the form of a long fiber (fibril) with transverse striations (bands).
98644	complex of collagen trimers	C	A complex of collagen trimers such as a fibril or collagen network.
98645	collagen network	C	A protein complex that consists of collagen triple helices associated to form a network.
98646	collagen sheet	C	A protein complex that consists of collagen triple helices associated to form a sheet-like network.
98647	collagen beaded filament	C	A supramolecular assembly of collagen trimers with a 'beads on a string'-like structure.
98648	collagen anchoring fibril	C	A specialised collagen fibril that functions as an anchor, binding to other collagen structures.
98649	response to peptidyl-dipeptidase A inhibitor	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptidyl-dipeptidase A inhibitor stimulus.
98650	peptidyl-proline 4-dioxygenase binding	F	Interacting selectively and non-covalently with a peptidyl-proline 4-dioxygenase.
98651	basement membrane collagen trimer	C	Any collagen timer that is part of a basement membrane.
98652	collagen type VII anchoring fibril	C	An antiparallel dimer of two collagen VII trimers, one end of which is embedded in the lamina densa while the other end attaches to banded collagen fibrils in the dermis.
98653	centromere clustering	P	The process by which centromeres/kinetochores become localized to clusters.
98654	CENP-A recruiting complex	C	A protein complex that includes Mis16(Yippee family) and/or Mis18 (WD repeat) subunits that is involved in the deposition of centromere specific (CENP-A containing) nucleosomes at the centromere.
98655	cation transmembrane transport	P	A process in which a cation is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.
98656	anion transmembrane transport	P	A process in which an anion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.
98657	import into cell	P	The directed movement of some substance from outside of a cell into the cytoplasmic compartment. This may occur via transport across the plasma membrane or via endocytosis.
98658	inorganic anion import into cell	P	The directed movement of inorganic anions from outside of a cell into the cytoplasmic compartment. This may occur via transport across the plasma membrane or via endocytosis.
98659	inorganic cation import into cell	P	The directed movement of inorganic cations from outside of a cell into the cytoplasmic compartment. This may occur via transport across the plasma membrane or via endocytosis.
98660	inorganic ion transmembrane transport	P	A process in which an inorganic ion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.
98661	inorganic anion transmembrane transport	P	A process in which an inorganic anion is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.
98662	inorganic cation transmembrane transport	P	A process in which an inorganic cation is transported from one side of a membrane to the other by means of some agent such as a transporter or pore.
98663	transmembrane transporter activity involved in import into cell	F	Any transmembrane transporter activity that is involved in importing some substance into a cell.
98664	G-protein coupled serotonin receptor signaling pathway	P	The series of molecular signals generated as a consequence of a G-protein coupled serotonin receptor binding to one of its physiological ligands.
98665	serotonin receptor complex	C	A protein complex that is capable of serotonin receptor activity.
98666	G-protein coupled serotonin receptor complex	C	A protein complex that is capable of G-protein coupled serotonin receptor activity.
98687	chromosomal region	C	Any subdivision of a chromosome along its length.
98700	neurotransmitter loading into synaptic vesicle	P	The active transport of neurotransmitters into a synaptic vesicle. This import is fuelled by an electrochemical gradient across the vesicle membrane, established by the action proton pumps.
98701	endocytic import into cell	P	The directed movement of some substance from the outside of a cell into a cytoplasmic vesicle via endocytosis.
98702	adenine import across plasma membrane	P	The directed movement of adenine from outside of a cell, across the plasma membrane and into the cytosol.
98703	calcium ion import across plasma membrane	P	The directed movement of calcium ions from outside of a cell, across the plasma membrane and into the cytosol.
98704	carbohydrate import across plasma membrane	P	The directed movement of a carbohydrate from outside of a cell, across the plasma membrane and into the cytosol.
98705	copper ion import across plasma membrane	P	The directed movement of copper ions from outside of a cell, across the plasma membrane and into the cytosol.
98706	ferric iron import across plasma membrane	P	The directed movement of ferric iron ions (Fe(III) or Fe3+) from outside of a cell, across the plasma membrane and into the cytosol.
98707	ferrous iron import across plasma membrane	P	The directed movement of ferrous iron ions (Fe(II) or Fe2+) from outside of a cell, across the plasma membrane and into the cytosol.
98708	glucose import across plasma membrane	P	The directed movement of glucose from outside of a cell, across the plasma membrane and into the cytosol.
98709	glutathione import across plasma membrane	P	The directed movement of glutathione from outside of a cell, across the plasma membrane and into the cytosol.
98710	guanine import across plasma membrane	P	The directed movement of guanine from outside of a cell, across the plasma membrane and into the cytosol.
98711	iron ion import across plasma membrane	P	The directed movement of iron ions from outside of a cell, across the plasma membrane and into the cytosol.
98712	L-glutamate import across plasma membrane	P	The directed movement of L-glutamate from outside of a cell, across the plasma membrane and into the cytosol.
98713	leucine import across plasma membrane	P	The directed movement of leucine from outside of a cell, across the plasma membrane and into the cytosol.
98714	malate import across plasma membrane	P	The directed movement of malate from outside of a cell, across the plasma membrane and into the cytosol.
98715	malonic acid import across plasma membrane	P	The directed movement of malonic acid from outside of a cell, across the plasma membrane and into the cytosol.
98716	nickel cation import across plasma membrane	P	The directed movement of nickel cations from outside of a cell, across the plasma membrane and into the cytosol.
98717	pantothenate import across plasma membrane	P	The directed movement of pantothenate from outside of a cell, across the plasma membrane and into the cytosol.
98718	serine import across plasma membrane	P	The directed movement of serine from outside of a cell, across the plasma membrane and into the cytosol.
98719	sodium ion import across plasma membrane	P	The directed movement of sodium ions from outside of a cell, across the plasma membrane and into the cytosol.
98720	succinate import across plasma membrane	P	The directed movement of succinate from outside of a cell, across the plasma membrane and into the cytosol.
98721	uracil import across plasma membrane	P	The directed movement of uracil from outside of a cell, across the plasma membrane and into the cytosol.
98722	asymmetric stem cell division	P	Division of a stem cell during which it retains its identity and buds off a daughter cell with a new identity.
98723	skeletal muscle myofibril	C	A myofibril of a skeletal muscle fiber.
98724	symmetric stem cell division	P	Symmetric division of a stem cell to produce two stem cells of the same type as the parent. Symmetric stem cell division is necessary for amplification of stem cell populations in the absence of sources of stem cells external to an existing population.
98725	symmetric cell division	P	Cell division in which both daughter cells are of the same type.
98726	symmetric division of skeletal muscle satellite stem cell	P	The symmetric division of a skeletal muscle satellite stem cell, resulting in two skeletal muscle satellite stem cells. This process is involved in amplification of the pool of these cells.
98727	maintenance of cell number	P	Any process by which the numbers of cells of a particular type in a tissue are maintained.
98728	germline stem cell asymmetric division	P	The self-renewing division of a germline stem cell, to produce a daughter stem cell and a daughter germ cell which will divide to form one or more gametes.
98729	germline stem cell symmetric division	P	Division of a germline stem cell to produce two germline stem cells of the same type as the parent.
98730	male germline stem cell symmetric division	P	The symmetric division of a male germline stem cell to produce two male germline stem cells. An example of this is found in mammalian spermatogonial stem cells, some proportion of which divide symmetrically, so amplifying the population. The choice between asymmetric and symmetric division in this case appears to be internal and stochastic.
98731	skeletal muscle satellite stem cell maintenance involved in skeletal muscle regeneration	P	Any process by which the number of skeletal muscle satellite stem cells in a skeletal muscle is maintained during skeletal muscle regeneration. There are at least two mechanisms by which this is achieved. Skeletal muscle satellite stem cell asymmetric division ensures satellite stem cell numbers are kept constant. Symmetric division of these cells amplifies the number of skeletal muscle satellite stem cells.
98732	macromolecule deacylation	P	The removal of an acyl group, any group or radical of the form RCO- where R is an organic group, from a macromolecule.
98733	hemidesmosome associated protein complex	C	Any protein complex that is part of or has some part in a hemidesmosome.
98734	macromolecule depalmitoylation	P	The removal of palymitoyl groups from a macromolecule.
98735	positive regulation of the force of heart contraction	P	Any process that increases the force of heart muscle contraction.
98736	negative regulation of the force of heart contraction	P	Any process that decreases the force of heart muscle contraction.
98737	protein insertion into plasma membrane	P	The process that results in the incorporation of a protein into a plasma membrane. Incorporation in this context means having some part or covalently attached group that is inserted into the the hydrophobic region of one or both bilayers.
98739	import across plasma membrane	P	The directed movement of some substance from outside of a cell, across the plasma membrane and into the cytosol.
98740	multi organism cell adhesion	P	Cell adhesion that involves cells from multiple organisms or that is mediated by gene products from multiple organisms.
98741	adhesion between unicellular organisms via cell-wall interaction	P	The attachment of two unicellular organisms to each other via interaction between cell-wall components.
98742	cell-cell adhesion via plasma-membrane adhesion molecules	P	The attachment of one cell to another cell via adhesion molecules that are at least partially embedded in the plasma membrane.
98743	cell aggregation	P	The clustering together and adhesion of initially separate cells to form an aggregate. Examples include the clustering of unicellular organisms or blood cells in suspension and the condensation of mesenchymal cells during cartilage formation.
98744	1-phosphatidylinositol 4-kinase activator activity	F	Binds to and increases the activity of 1-phosphatidylinositol 4-kinase.
98745	Dcp1-Dcp2 complex	C	A protein complex consisting of a Dcp1 regulatory subunit and a Dcp2 catalytic subunit that has mRNA cap binding activity and is involved in decapping of nuclear-transcribed mRNA.
98746	fast, calcium ion-dependent exocytosis of neurotransmitter	P	The fast, initial phase of calcium ion-induced neurotransmitter release, via exocytosis, into the synaptic cleft. This depends on low affinity calcium sensors and typically begins a fraction of a millisecond after Ca2+ influx, and decays rapidly (1-10ms) with a decay constant of around 5-10ms. The underlying molecular mechanisms of this process are distinct from those of the later, slow phase of release.
98747	slow, calcium ion-dependent exocytosis of neurotransmitter	P	The slow, second phase of calcium ion-induced neurotransmitter release, via exocytosis, into the synaptic cleft. This depends on high affinity calcium sensors and decays slowly, typically with a decay constant of over 100ms. The underlying molecular mechanisms of this process are distinct from those of the earlier, fast phase of release.
98748	endocytic adaptor activity	F	The binding activity of a molecule that brings together two or more protein molecules, or a protein and another macromolecule or complex as a key step in receptor mediated endocytosis.
98749	cerebellar neuron development	P	The process whose specific outcome is the progression of a cerebellar neuron over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.
98750	FYXD domain binding	F	Interacting selectively and non-covalently with a FXYD domain.
98751	bone cell development	P	The process whose specific outcome is the progression of a bone cell over time, from initial commitment of the cell to a specific fate, to the fully functional differentiated cell.
98752	integral component of the cytoplasmic side of the plasma membrane	C	The component of the plasma membrane consisting of the gene products that penetrate only the cytoplasmic side of the membrane.
98753	anchored component of the cytoplasmic side of the plasma membrane	C	The component of the plasma membrane consisting of gene products and protein complexes with covalently attached hydrophobic anchors products that penetrate only the cytoplasmic side of the membrane.
98754	detoxification	P	Any process that reduces or removes the toxicity of a toxic substance. These may include transport of the toxic substance away from sensitive areas and to compartments or complexes whose purpose is sequestration of the toxic substance.
98755	maintenance of seed dormancy by absisic acid	P	The process by which seed dormancy is maintained by the presence of absisic acid.
98756	response to interleukin-21	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-21 stimulus.
98757	cellular response to interleukin-21	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-21 stimulus.
98758	response to interleukin-8	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-8 stimulus.
98759	cellular response to interleukin-8	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-8 stimulus.
98760	response to interleukin-7	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-7 stimulus.
98761	cellular response to interleukin-7	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an interleukin-7 stimulus.
98762	meiotic cell cycle phase	P	One of the distinct periods or stages into which the meiotic cell cycle is divided. Each phase is characterized by the occurrence of specific biochemical and morphological events.
98763	mitotic cell cycle phase	P	One of the distinct periods or stages into which the mitotic cell cycle is divided. Each phase is characterized by the occurrence of specific biochemical and morphological events.
98764	meiosis I cell cycle phase	P	A meiotic cell cycle phase prior to a during which some part of meiosis I nuclear division or the proceeding cytokinesis occurs.
98765	meiosis II cell cycle phase	P	A meiotic cell cycle phase that occurs after meiosis I (the first meiotic nuclear division).
98768	meiotic prometaphase I	P	The meiotic cell cycle phase in eukaryotes between meiotic prophase I and meiotic metaphase I. During meiotic prometaphase I, the nuclear envelope breaks down and one kinetochore forms per chromosome. Chromosomes attach to spindle microtubules and begin to move towards the metaphase plate.
98769	TIMP family protein binding	F	Interacting selectively and non-covalently with any member of the Tissue inhibitors of metalloproteinases (TIMPs) family. TIMPs are endogenous protein regulators of the matrix metalloproteinase (MMPs) family
98770	FBXO family protein binding	F	Interacting selectively and non-covalently with any member of the FBXO protein family. Members of this family have an F-box protein motif of approximately 50 amino acids that functions as a site of protein-protein interaction.
98771	inorganic ion homeostasis	P	Any process involved in the maintenance of an internal steady state of inorganic ions within an organism or cell.
98772	molecular function regulator	F	A molecular function that modulates the activity of a gene product or complex. Examples include enzyme regulators and channel regulators.
98773	skin epidermis development	P	The process whose specific outcome is the progression of the skin epidermis over time, from its formation to the mature structure.
98774	curli	C	A proteinaceous extracellular fiber, produced by an enteric bacterium, that is involved in surface and cell-cell contacts that promote community behavior and host colonization.
98775	curli assembly	P	The process of assembly of curli, extracellular fibers produced by enteric bacteria. This process occurs outside the cell, where it is coupled to secretion across the cell outer membrane via nucleation by elements of the transporter complex.
98776	protein transport across the cell outer membrane	P	The directed movement of proteins across the cell outer membrane.
98777	protein secretion by the type VIII secretion system	P	Protein secretion through the outer membrane via the mechanism used for the secretion of curli subunits.
98778	curli subunit secretion coupled to curli assembly	P	The secretion of soluble curli subunits through the outer membrane, coupled to nucleation of curli fiber formation at the membrane surface.
98779	mitophagy in response to mitochondrial depolarization	P	The macromitophagy process that is triggered by a detection of the loss of mitochondrial membrane potential.
98780	response to mitochondrial depolarisation	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) in response to the depolarization of one or more mitochondria.
98781	ncRNA transcription	P	The transcription of non (protein) coding RNA from a DNA template.
98782	mechanically-gated potassium channel activity	F	Enables the transmembrane transfer of a potassium ion by a channel that opens in response to a mechanical stress.
98783	correction of merotelic kinetochore attachment, mitotic	P	The cell cycle process that corrects the anomalous association of a single chromatid kinetochore with mitotic spindle microtubules emanating from both spindle poles (otherwise known as merotelic attachment to the spindle).
98784	biofilm matrix organization	P	A process that results in the assembly, arrangement of constituent parts, or disassembly of a biofilm matrix.
98785	biofilm matrix assembly	P	A process that results in the assembly of a biofilm matrix.
98786	biofilm matrix disassembly	P	A process that results in the disassembly of a biofilm matrix.
98787	mRNA cleavage involved in mRNA processing	P	Cleavage of an immature mRNA transcript to produce one or more more mature mRNA transcripts, prior to translation into polypeptide.
98788	dendritic knob	C	The terminal swelling of an apical dendrite of a ciliated olfactory receptor neuron. Each knob gives rise to 5 to 20 long delicate nonmotile cilia, which extend into the mucus covering the sensory epithelium.
98789	pre-mRNA cleavage required for polyadenylation	P	The targeted, endonucleolytic cleavage of a pre-mRNA, required for polyadenylation of the 3' end. This cleavage is directed by binding sites near the 3' end of the mRNA and leaves a 3' hydoxyl end which then becomes a target for adenylation.
98790	ncRNA transcription associated with protein coding gene TSS/TES	P	The transcription of non-coding RNA associated with transcriptional start and end sites of protein coding genes. This occurs at some low level for many protein coding genes.
98791	Golgi subcompartment	C	A compartment that consists of a lumen and an enclosing membrane, and is part of the Golgi Apparatus.
98792	xenophagy	P	The macroautophagy process in which a region of cytoplasm containing an intracellular pathogen or some part of an intracellular pathogen (e.g. viral capsid) is enclosed in a double membrane bound autophagosome, which then fuses with the lysosome leading to degradation of the contents.
98793	presynapse	C	The part of a synapse that is part of the presynaptic cell.
98794	postsynapse	C	The part of a synapse that is part of the post-synaptic cell.
98795	mRNA cleavage involved in gene silencing	P	Cleavage of an mRNA occurring as part of the mechanism of gene silencing.
98796	membrane protein complex	C	Any protein complex that is part of a membrane.
98797	plasma membrane protein complex	C	Any protein complex that is part of the plasma membrane.
98798	mitochondrial protein complex	C	A protein complex that is part of a mitochondrion.
98799	outer mitochondrial membrane protein complex	C	Any protein complex that is part of the outer mitochondrial membrane.
98800	inner mitochondrial membrane protein complex	C	Any protein complex that is part of the inner mitochondrial membrane.
98801	regulation of renal system process	P	Any process that modulates the frequency, rate or extent of a system process, a multicellular organismal process carried out by the renal system.
98802	plasma membrane receptor complex	C	Any protein complex that is part of the plasma membrane and which functions as a receptor.
98803	respiratory chain complex	C	Any protein complex that is part of a respiratory chain
98804	non-motile cilium membrane	C	The portion of the plasma membrane surrounding a non-motile cilium.
98805	whole membrane	C	Any lipid bilayer that completely encloses some structure, and all the proteins embedded in it or attached to it. Examples include the plasma membrane and most organelle membranes.
98806	deadenylation involved in gene silencing by miRNA	P	Shortening of the poly(A) tail of a nuclear-transcribed mRNA following miRNA binding to mRNA, resulting in destabilization of the mRNA and a reduction in the efficiency of its translation.
98807	chloroplast thylakoid membrane protein complex	C	A protein complex that is part of a chloroplast thylakoid membrane.
98808	mRNA cap binding	F	Interacting selectively and non-covalently with a 7-methylguanosine (m7G) group or derivative located at the 5' end of an mRNA molecule.
98809	nitrite reductase activity	F	Catalysis of the reaction: nitrite + acceptor = product(s) of nitrate reduction + reduced acceptor.
98810	neurotransmitter reuptake	P	The directed movement of neurotransmitter molecules from the extrasynaptic space into the presynaptic cytosol.
98811	transcriptional repressor activity, RNA polymerase II activating transcription factor binding	F	Interacting selectively and non-covalently with an RNA polymerase II activating transcription factor and also with the RNA polymerase II basal transcription machinery in order to stop, prevent, or reduce the frequency, rate or extent of transcription.
98812	nuclear rRNA polyadenylation involved in polyadenylation-dependent rRNA catabolic process	P	The enzymatic addition of a sequence of adenylyl residues (polyadenylation) at the 3' end of a rRNA, occurring as part of the process of polyadenylation-dependent rRNA catabolism in the nucleus.
98813	nuclear chromosome segregation	P	The process in which genetic material, in the form of nuclear chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets. Nuclear chromosome segregation begins with the condensation of chromosomes, includes chromosome separation, and ends when chromosomes have completed movement to the spindle poles.
98814	spontaneous synaptic transmission	P	The low level of synaptic transmission that occurs via spontaneous neurotransmitter release into the synaptic cleft in the absence of a presynaptic action potential.
98815	modulation of excitatory postsynaptic potential	P	Any process that modulates the frequency, rate or extent of excitatory postsynaptic potential (EPSP). EPSP is a process that leads to a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell. The flow of ions that causes an EPSP is an excitatory postsynaptic current (EPSC) and makes it easier for the neuron to fire an action potential.
98816	mini excitatory postsynaptic potential	P	A process that leads to a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell, induced by the spontaneous release of a single vesicle of an excitatory neurotransmitter into the synapse.
98817	evoked excitatory postsynaptic potential	P	A process that leads to a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell induced by the evoked release of many vesicles of excitatory neurotransmitter at the synapse.
98818	hyperpolarization of postsynaptic membrane	P	A process that hyerpolarizes a postsynaptic membrane relative to its resting potential. This has an inhibitory effect on the post-synaptic cell, moving the membrane potential away from the firing threshold.
98819	depolarization of postsynaptic membrane	P	A process that depolarizes a postsynaptic membrane relative to its resting potential. This has an excitatory effect on the post-synaptic cell, moving the membrane potential towards the firing threshold.
98820	trans-synaptic protein complex	C	A protein complex that spans the synaptic cleft and has parts in both the pre- and post-synaptic membranes.
98821	BMP receptor activity	F	Combining with a member of the bone morphogenetic protein (BMP) family, and transmitting a signal across the plasma membrane to initiate a change in cell activity.
98822	peptidyl-cysteine modification to L-cysteine persulfide	P	The modification of peptidyl-cysteine to form peptidyl-L-cysteine persulfide.
98823	peptidyl-cysteine modification to S-amindino-L-cysteine	P	The amidinylation of peptidyl-cysteine to form peptidyl-S-amidino-L-cysteine.
98824	petidyl-cysteine sulfation	P	The sulfation of peptidyl-cysteine to form S-sulfo-L-cysteine.
98825	peptidyl-histidine guanylation	P	The guanylylation of peptidyl-histidine to form (phospho-5'-guanosine)-L-histidine.
98826	endoplasmic reticulum tubular network membrane	C	The membrane of the endoplasmic reticulum tubular network.
98827	endoplasmic reticulum subcompartment	C	A distinct region of the endoplasmic reticulum
98828	modulation of inhibitory postsynaptic potential	P	Any process that modulates the frequency, rate or extent of inhibitory postsynaptic potential (IPSP). IPSP is a temporary decrease in postsynaptic membrane potential due to the flow of negatively charged ions into the postsynaptic cell. The flow of ions that causes an IPSP is an inhibitory postsynaptic current (IPSC) and makes it more difficult for the neuron to fire an action potential.
98829	intestinal folate absorption	P	Uptake of folic into the blood by absorption from the small intestine.
98830	presynaptic endosome	C	An endosome present in the presynapse that fuses with endocytic vesicles arising in the presynaptic endocytic zone. This organelle is believed to be involved in regeneration of synaptic vesicles.
98831	presynaptic active zone cytoplasmic component	C	A specialized region below the presynaptic membrane, characterized by electron-dense material, a specialized cytoskeletal matrix and accumulated (associated) synaptic vesicles.
98832	peri-centrosomal recycling endosome	C	A recycling endosome that is organized around the microtubule organizing center, close to the nucleus. This is the main recycling endosome of most cells. It receives input from the Golgi as well as recycled molecules from early endosomes.
98833	presynaptic endocytic zone	C	A specialized region of the plasma membrane and underlying cytoplasm which surround the the active zone, into which synaptic vesicle membranes are recycled following exocytosis. It is especially enriched in endocytic proteins following intense activity.
98834	presynaptic endocytic zone cytoplasmic component	C	The cytoplasmic component of the presynaptic endocytic zone.
98835	presynaptic endocytic zone membrane	C	The region of the presynaptic membrane that is part of the presynaptic endocytic zone - where synaptic vesicles are endocytosed and recycled following release.
98836	cytoskeleton of dendritic spine	C	The portion of the cytoskeleton that lies within a dendritic spine. The actin component of this cytoskeleton is involved in spine head remodelling in response to postsynaptic signalling.
98837	postsynaptic recycling endosome	C	A recycling endosome of the postsynapse. In postsynaptic terminals with dendritic spines, it is typically located at the base of a dendritic spine. It is involved in recycling of neurotransmitter receptors to the postsynaptic membrane. In some cases at least, this recycling is activated by postsynaptic signalling and so can play a role in long term potentiation.
98838	reduced folate transmembrane transport	P	The directed movement of reduced folate (dihydrofolate, tetrahydrofolate, methylene-tetrahydrofolate or methyl-tetrahydrofolate) across a membrane.
98839	postsynaptic density membrane	C	The membrane component of the postsynaptic density. This is the region of the postsynaptic membrane in which the population of neurotransmitter receptors involved in synaptic transmission are concentrated.
98840	protein transport along microtubule	P	The directed movement of a protein along a microtubule, mediated by motor proteins.
98841	protein localization to cell division site after cytokinesis	P	A cellular protein localization process in which a protein is transported to, or maintained at, the site of cell division following cytokinesis.
98842	postsynaptic early endosome	C	An early endosome of the postsynapse. It acts as the major sorting station on the endocytic pathway, targeting neurotransmitter receptors for degregation or recycling.
98843	postsynaptic endocytic zone	C	A stably positioned site of clathrin adjacent and physically attached to the postsynaptic specialization, which is the site of endocytosis of post-synaptic proteins.
98844	postsynaptic endocytic zone membrane	C	The region of the postsynaptic membrane that is part of the postsynaptic endocytic zone. This region of membrane is associated with stable clathrin puncta.
98845	postsynaptic endosome	C	An endosomal compartment that is part of the post-synapse. Only early and recycling endosomes are typically present in the postsynapse.
98846	podocyte foot	C	A cell projection of a podocyte (glomerular visceral epithelial cell) forming a foot-like structure projecting from a podocyte primary projection, that wraps around capillaries of a renal glomerulus. Adjacent feet (pedicels) interdigitate, leaving thin filtration slits between them, which are covered by slit diaphragms.
98847	sequence-specific single stranded DNA binding	F	Interacting selectively and non-covalently with single-stranded DNA of a specific nucleotide composition.
98848	alpha-D-ribose 1-methylphosphonate 5-phosphate C-P-lyase activity	F	Catalysis of the reaction: alpha-D-ribose 1-methylphosphonate 5-phosphate = alpha-D-ribose 1,2-cyclic phosphate 5-phosphate + methane.
98849	cellular detoxification of cadmium ion	P	Any process that reduces or removes the toxicity of cadmium cations in a cell. These include transport of cadmium cations away from sensitive areas and to compartments or complexes whose purpose is sequestration.
98850	extrinsic component of synaptic vesicle membrane	C	The component of the synaptic vesicle membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
98851	double-stranded miRNA binding	F	Interacting selectively and non-covalently with double-stranded miRNA. double-stranded miRNA is formed by processing of pre-miRNA stem-loop structures.
98852	lytic vacuole membrane	C	The lipid bilayer surrounding a lytic vacuole and separating its contents from the cytoplasm of the cell.
98853	ER-vacuole membrane contact site	C	A zone of apposition between endoplasmic-reticulum and lytic vacuole membranes, structured by bridging complexes.
98854	podocyte primary projection	C	A cell projection originating from a renal glomerular podocyte and extending to the renal glomerular podocyte foot.
98855	HCN channel complex	C	A cation ion channel that consists of a tetramer of HCN family members, has a preference for K+ over Na+ ions and is activated by membrane hyperpolarization. Some members of this family (HCN1, HCN2 and HCN4) are also activated when cAMP binds to their cyclic nucleotide binding domain (CNBD). Channel complexes of this family play an important role in the control of pacemaker activity in the heart.
98856	intestinal lipid absorption	P	Any process in which lipids are taken up from the contents of the intestine.
98857	membrane microdomain	C	A membrane region with a lipid composition that is distinct from that of the membrane regions that surround it.
98858	actin-based cell projection	C	A cell projection supported by an assembly of actin filaments, and which lacks microtubules.
98859	actin filament bundle of actin-based cell projection	C	A bundle of cross-linked actin filaments that is part of an actin-based cell protrusion, in which filaments are oriented such that the plus (barbed) ends are at the tip of the protrusion, capped by a tip complex which stabilizes the filaments.
98860	actin filament bundle of stereocilium	C	A bundle of hundreds of cross-linked actin filaments (an actin cable), that is the supporting structure of a stereocilium. Filaments are oriented such that the the plus (barbed) ends are at the tip of the protrusion and are capped by a tip complex which bridges to the plasma membrane.
98861	actin filament bundle of filopodium	C	A parallel bundle of actin filaments that is part of filopodium. Filaments are oriented such that the plus (barbed) ends are at the tip of the protrusion, capped by a tip complex.
98862	cluster of actin-based cell projections	C	A cell part consisting of multiple, closely packed actin-based cell projections.
98863	nuclear migration by microtubule mediated pushing forces	P	The directed movement of the nucleus by pushing forces exerted by polymerization of backward-extending microtubules.
98864	modification by symbiont of host occluding cell-cell junction	P	The process in which a symbiont organism effects a change in the structure or function of its host occluding junction, a cell-cell junction that seals cells together in an epithelium in a way that prevents even small molecules from leaking from one side of the sheet to the other.
98865	modification by symbiont of host bicellular tight junctions	P	The process in which an organism effects a change in the structure or function of its host bicellular tight junctions, an occluding cell-cell junction that is composed of a branching network of sealing strands that completely encircles the apical end of each cell in an epithelial sheet
98866	multivesicular body fusion to apical plasma membrane	P	The fusion of the membrane of a multivesicular body with the apical plasma membrane, resulting in release of exosomes from the cell.
98867	intramembranous bone growth	P	The increase in size or mass of an intramembranous bone that contributes to the shaping of the bone.
98868	bone growth	P	The increase in size or mass of a bone that contributes to the shaping of that bone.
98869	cellular oxidant detoxification	P	Any process carried out at the cellular level that reduces or removes the toxicity superoxide radicals or hydrogen peroxide.
98870	action potential propagation	P	The propagation of an action potential along the plane of an excitable membrane. Action potentials typically propagate once triggered because the depolarization of adjacent membrane regions due to an action potential crosses the firing threshold.
98871	postsynaptic actin cytoskeleton	C	The actin cytoskeleton that is part of a postsynapse
98872	G-protein coupled neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration	F	G-protein coupled neurotransmitter receptor activity, occurring in the postsynaptic membrane that is involved in regulating the cytosolic concentration of calcium ions in the postsynapse.
98873	neuronal action potential back-propagation	P	Propagation of an action potential in a neuron, from its site of initiation (typically the axon hillock) towards the soma.
98874	spike train	P	A series of sequential, propagated action potentials occurring in a single cell.
98875	epididymosome	C	A microvesicle of the epididymal fluid, from which spermatozoa aquire membrane proteins.
98876	vesicle-mediated transport to the plasma membrane	P	The directed movement of substances to the plasma membrane in transport vesicles that fuse with the plasma membrane by exocytosis.
98877	neurotransmitter receptor transport to plasma membrane	P	The directed movement of neurotransmitter receptor to the plasma membrane in transport vesicles.
98878	neurotransmitter receptor complex	C	Any protein complex that is capable of functioning as a neurotransmitter receptor.
98879	structural constituent of postsynaptic specialization	F	The action of a molecule that contributes to the structural integrity of a postsynaptic specialization.
98880	maintenance of postsynaptic specialization structure	P	A process which maintains the organization and the arrangement of proteins in the presynaptic specialization.
98881	exocytic insertion of neurotransmitter receptor to plasma membrane	P	The exocytic fusion of neurotransmitter receptor containing vesicles with a plasma-membrane resulting in the integration of NT receptors with the plasma-membrane. This process includes tethering and docking steps that prepare vesicles for fusion.
98882	structural constituent of presynaptic active zone	F	The action of a molecule that contributes to the structural integrity of a presynaptic active zone.
98883	synapse disassembly	P	A cellular process that results in the controlled breakdown of synapse. After it starts the process is continuous until the synapse has disappeared
98884	postsynaptic neurotransmitter receptor internalization	P	A receptor-mediated endocytosis process that results in the internalization of a neurotransmitter receptor from the postsynaptic membrane endocytic zone into an endocytic vesicle.
98885	modification of postsynaptic actin cytoskeleton	P	Any process that modifies the structure of a postsynaptic actin cytoskeleton.
98886	modification of dendritic spine	P	Any process that modifies the structure of a dendritic spine.
98887	neurotransmitter receptor transport, endosome to postsynaptic membrane	P	The directed movement of neurotransmitter receptor from the postsynaptic endosome to the postsynaptic membrane in transport vesicles.
98888	extrinsic component of presynaptic membrane	C	The component of the presynaptic membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
98889	intrinsic component of presynaptic membrane	C	The component of the presynaptic membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.
98890	extrinsic component of postsynaptic membrane	C	The component of the postsynaptic membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
98891	extrinsic component of presynaptic active zone membrane	C	The component of the presynaptic active zone membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
98892	extrinsic component of postsynaptic specialization membrane	C	The component of the postsynaptic specialization membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
98893	extrinsic component of postsynaptic endocytic zone	C	The component of the postsynaptic endocytic zone membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
98894	extrinsic component of presynaptic endocytic zone membrane	C	The component of the presynaptic endocytic zone membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
98895	postsynaptic endosome membrane	C	The lipid bilayer surrounding a postsynaptic endosome.
98896	postsynaptic early endosome membrane	C	The lipid bilayer surrounding a postsynaptic early endosome.
98897	spine apparatus membrane	C	The lipid bilayer surrounding the spine apparatus.
98898	dense core granule lumen	C	The volume enclosed by the dense core granule membrane.
98899	spine apparatus lumen	C	The volume enclosed by the spine apparatus membrane.
98900	regulation of action potential	P	Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination. This typically occurs via modulation of the activity or expression of voltage-gated ion channels.
98901	regulation of cardiac muscle cell action potential	P	Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in a cardiac muscle cell. This typically occurs via modulation of the activity or expression of voltage-gated ion channels.
98902	regulation of membrane depolarization during action potential	P	Any process that modulates the rate, frequency or extent of membrane depolarization during an action potential. Membrane depolarization is the process in which membrane potential changes in the depolarizing direction from the resting potential.
98903	regulation of membrane repolarization during action potential	P	Any process that modulates the rate, frequency or extent of membrane repolarization during an action potential. Membrane repolarization is the process in which membrane potential changes in the repolarizing direction, towards the resting potential.
98904	regulation of AV node cell action potential	P	Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in an atrioventricular node myocyte. This typically occurs via modulation of the activity or expression of voltage-gated ion channels.
98905	regulation of bundle of His cell action potential	P	Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in a cardiac muscle cell of the bundle of His. This typically occurs via modulation of the activity or expression of voltage-gated ion channels.
98906	regulation of Purkinje myocyte action potential	P	Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in a Purkinje myocyte. This typically occurs via modulation of the activity or expression of voltage-gated ion channels.
98907	regulation of SA node cell action potential	P	Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in an SA node cardiac myocyte. This typically occurs via modulation of the activity or expression of voltage-gated ion channels.
98908	regulation of neuronal action potential	P	Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in a neuron. This typically occurs via modulation of the activity or expression of voltage-gated ion channels.
98909	regulation of cardiac muscle cell action potential involved in regulation of contraction	P	Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in a cardiac muscle cell contributing to the regulation of its contraction.
98910	regulation of atrial cardiac muscle cell action potential	P	Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in an atrial cardiac muscle cell contributing to the regulation of its contraction. This typically occurs via modulation of the activity or expression of voltage-gated ion channels.
98911	regulation of ventricular cardiac muscle cell action potential	P	Any process that modulates the frequency, rate or extent of action potential creation, propagation or termination in a ventricular cardiac muscle cell contributing to the regulation of its contraction. This typically occurs via modulation of the activity or expression of voltage-gated ion channels.
98912	membrane depolarization during atrial cardiac muscle cell action potential	P	The process in which atrial cardiac muscle cell membrane potential changes in the depolarizing direction from the negative resting potential towards the positive membrane potential that will be the peak of the action potential.
98913	membrane depolarization during ventricular cardiac muscle cell action potential	P	The process in which ventricular cardiac muscle cell membrane potential changes in the depolarizing direction from the negative resting potential towards the positive membrane potential that will be the peak of the action potential.
98914	membrane repolarization during atrial cardiac muscle cell action potential	P	The process in which ions are transported across a membrane such that the atrial cardiomyocyte membrane potential changes in the direction from the positive membrane potential at the peak of the action potential towards the negative resting potential.
98915	membrane repolarization during ventricular cardiac muscle cell action potential	P	The process in which ions are transported across a membrane such that the ventricular cardiomyocyte membrane potential changes in the direction from the positive membrane potential at the peak of the action potential towards the negative resting potential.
98916	anterograde trans-synaptic signaling	P	Cell-cell signaling from pre to post-synapse, across the synaptic cleft
98917	retrograde trans-synaptic signaling	P	Cell-cell signaling from post to pre-synapse, across the synaptic cleft
98918	structural constituent of synapse	F	The action of a molecule that contributes to the structural integrity of a synapse.
98919	structural constituent of postsynaptic density	F	The action of a molecule that contributes to the structural integrity of a postsynaptic density.
98920	retrograde trans-synaptic signaling by lipid	P	Cell-cell signaling from postsynapse to presynapse, across the synaptic cleft, mediated by a lipid ligand.
98921	retrograde trans-synaptic signaling by endocannabinoid	P	Cell-cell signaling from postsynapse to presynapse, across the synaptic cleft, mediated by an endocannabinoid ligand.
98922	extrinsic component of dense core granule membrane	C	The component of the dense core granule membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
98923	retrograde trans-synaptic signaling by soluble gas	P	Cell-cell signaling from postsynapse to presynapse, across the synaptic cleft, mediated by an soluble gas ligand.
98924	retrograde trans-synaptic signaling by nitric oxide	P	Cell-cell signaling from postsynapse to presynapse, across the synaptic cleft, mediated by nitric oxide.
98925	retrograde trans-synaptic signaling by nitric oxide, modulating synaptic transmission	P	Modulation of synaptic transmission by cell-cell signaling from postsynapse to presynapse, across the synaptic cleft, mediated by nitric oxide.
98926	postsynaptic signal transduction	P	Signal transduction in which the initial step occurs in a postsynapse.
98927	vesicle-mediated transport between endosomal compartments	P	A cellular transport process in which transported substances are moved in membrane-bounded vesicles between endosomal compartments, e.g, between early endosome and sorting endosome.
98928	presynaptic signal transduction	P	Signal transduction in which the initial step occurs in a presynapse.
98929	extrinsic component of spine apparatus membrane	C	The component of the spine apparatus membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
98930	axonal transport	P	The directed movement of organelles or molecules along microtubules in axons.
98931	virion attachment to host cell flagellum	P	The process by which a virion attaches to a the host cell flagellum. Some DNA bacterial viruses use flagella to attach to the host cell. This contact with the flagellum facilitates concentration of phage particles around the entry receptor on the bacterial cell surface.
98932	disruption by virus of host cell wall petidoglycan during virus entry	P	A process carried out by a virus that breaks down peptidoglycans in the cell wall of its host during viral entry.
98933	disruption by symbiont of host cell envelope	P	The process by which a symbiont breaks down the cell wall of its host. The host is defined as the larger of the organisms involved in a symbiotic interaction.
98934	retrograde dendritic transport	P	The directed movement of organelles or molecules along microtubules in a dendrite from the postsynapse towards the cell body.
98935	dendritic transport	P	The directed movement of organelles or molecules along microtubules in dendrites.
98936	intrinsic component of postsynaptic membrane	C	The component of the postsynaptic membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.
98937	anterograde dendritic transport	P	The directed movement of organelles or molecules along microtubules from the cell body toward the postsynapse in dendrites.
98938	actin cytoskeleton of dendritic spine	C	The actin cytoskeleton that is part of a dendritic spine.
98939	dendritic transport of mitochondrion	P	The directed movement of mitochondria along microtubules in nerve cell dendrites.
98940	anterograde trans-synaptic signaling by nitric oxide	P	Cell-cell signaling from presynapse to postynapse, across the synaptic cleft, mediated by nitric oxide.
98941	anterograde trans-synaptic signaling by trans-synaptic protein complex	P	Cell-cell signaling from postsynapse to presynapse, across the synaptic cleft, mediated by a trans-synaptic protein complex.
98942	retrograde trans-synaptic signaling by trans-synaptic protein complex	P	Cell-cell signaling from postsynapse to presynapse, across the synaptic cleft, mediated by trans-synaptic protein complex.
98943	neurotransmitter receptor transport, postsynaptic endosome to lysosome	P	The directed movement of neurotransmitter receptor from the postsynaptic endosome in tranpsort vesicles to the lysosome for degradation.
98944	postsynaptic recycling endosome membrane	C	The lipid bilayer surrounding a postsynaptic recycling endosome.
98945	intrinsic component of presynaptic active zone membrane	C	The component of the presynaptic active zone membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.
98946	intrinsic component of presynaptic endocytic zone membrane	C	The component of the presynaptic endocytic zone membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.
98947	intrinsic component of postsynaptic endocytic zone membrane	C	The component of the postsynaptic endocytic zone membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.
98948	intrinsic component of postsynaptic specialization membrane	C	The component of the postsynaptic specialization membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.
98949	intrinsic component of postsynaptic endosome membrane	C	The component of the postsynaptic endosome membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.
98950	intrinsic component of postsynaptic early endosome membrane	C	The component of the postsynaptic early endosome membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.
98951	intrinsic component of postsynaptic recycling endosome membrane	C	The component of the postsynaptic recycling endosome membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.
98952	intrinsic component of spine apparatus membrane	C	The component of the spine apparatus membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.
98953	receptor diffusion trapping	P	The process by which a membrane receptor, diffusing freely within the plasma membeane, becomes trapped in some plasma membrane region. This can happen when a receptor bind, directly or indirectly, to some component of the underlying matrix.
98954	presynaptic endosome membrane	C	The lipid bilayer surrounding a presynaptic endosome.
98955	intrinsic component of presynaptic endosome membrane	C	The component of the presynaptic endosome membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.
98956	intrinsic component of dense core granule membrane	C	The component of the dense core granule membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.
98957	anterograde axonal transport of mitochondrion	P	The directed movement of mitochondria along microtubules in axons away from the cell body and towards the presynapse.
98958	retrograde axonal transport of mitochondrion	P	The directed movement of mitochondria along microtubules in axons towards the cell body and away from the presynapse.
98959	retrograde dendritic transport of mitochondrion	P	The directed movement of mitochondria along microtubules in dendrites towards the cell body and away from the postsynapse.
98960	postsynaptic neurotransmitter receptor activity	F	
98961	dendritic transport of ribonucleoprotein complex	P	The directed movement of a ribonucleoprotein complex along microtubules in nerve cell dendrites.
98962	regulation of postsynaptic neurotransmitter receptor activity	P	Any process that modulates the frequency, rate or extent of neurotransmitter receptor activity involved in synaptic transmission. Modulation may be via an effect on ligand affinity, or effector funtion such as ion selectivity or pore opening/closing in ionotropic receptors.
98963	dendritic transport of messenger ribonucleoprotein complex	P	The directed movement of a messenger ribonucleoprotein complex along microtubules in nerve cell dendrites.
98964	anterograde dendritic transport of messenger ribonucleoprotein complex	P	The directed movement of a messenger ribonucleoprotein complex along microtubules in nerve cell dendrites towards the postsynapse.
98965	extracellular matrix of synaptic cleft	C	The portion of the extracellular matrix that lies within the synaptic cleft.
98966	perisynaptic extracellular matrix	C	The portion of the extracellular matrix that lies within the perisynaptic space.
98967	exocytic insertion of neurotransmitter receptor to postsynaptic membrane	P	The exocytic fusion of neurotransmitter receptor containing vesicles with a plasma-membrane resulting in the integration of NT receptors with the plasma-membrane enabling them to participate in neurotransmitter reception. This process includes tethering and docking steps that prepare vesicles for fusion.
98968	neurotransmitter receptor transport postsynaptic membrane to endosome	P	Vesicle-mediated transport of a neurotransmitter receptor complex from the postsynaptic membrane to the postsynaptic early endosome.
98969	neurotransmitter receptor transport to postsynaptic membrane	P	The directed movement of neurotransmitter receptor to the postsynaptic membrane in transport vesicles.
98970	postsynaptic neurotransmitter receptor diffusion trapping	P	The process by which diffusing neurotransmitter receptor becomes trapped at the postsynaptic specialization membrane. This is typically due to interaction with components of the post-synaptic specialization.
98971	anterograde dendritic transport of neurotransmitter receptor complex	P	The directed movement of a neurotransmitter receptor complex along microtubules in nerve cell dendrites towards the postsynapse.
98972	anterograde dendritic transport of mitochondrion	P	The directed movement of mitochondria along microtubules in dendrites towards the postsynapse and away from the cell body.
98973	structural constituent of postsynaptic actin cytoskeleton	F	The action of a molecule that contributes to the structural integrity of a postsynaptic actin cytoskeleton.
98974	postsynaptic actin cytoskeleton organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of cytoskeletal structures comprising actin filaments and their associated proteins in the postsynaptic actin cytoskeleton.
98975	postsynapse of neuromuscular junction	C	The postsynapse of a neuromuscular junction. In vertebrate muscles this includes the motor end-plate, consisting of postjunctional folds of the sarcolemma.
98976	excitatory chemical synaptic transmission	P	Synaptic transmission that results in an excitatory postsynaptic potential.
98977	inhibitory chemical synaptic transmission	P	Synaptic transmission that results in an inhibitory postsynaptic potential.
98978	glutamatergic synapse	C	A synapse that uses glutamate as a neurotransmitter.
98979	polyadic synapse	C	A synapse consisting of a single presynapse and multiple postsynapses. These postsynapses may come from the same cell of from different cells. Polyadic synapses are common in arthropod and nematode central nervous systems.
98980	presynaptic density	C	An electron dense specialization of the presynaptic active zone cytoskeleton.
98981	cholinergic synapse	C	A synapse that uses acetylcholine as a neurotransmitter.
98982	GABA-ergic synapse	C	A synapse that uses GABA as a neurotransmitter. These synapses are typically inhibitory.
98983	symmetric, GABA-ergic, inhibitory synapse	C	An neuron to neuron synapse that lacks an electron dense postsynaptic specialization, uses GABA as a neurotransmitter and whose activity results in inhibitory postsynaptic potentials.
98984	neuron to neuron synapse	C	A synapse in which pre and post-synaptic cells are neurons.
98985	asymmetric, glutamatergic, excitatory synapse	C	An neuron to neuron synapse with a postsynaptic density, that uses glutamate as a neurotransmitter and whose activity results in excitatory postsynaptic potentials.
98986	T-bar	C	A T-shaped presynpatic density. These are common in arhropod central nervous systems.
98987	regulation of modification of synapse structure, modulating synaptic transmission	P	Any process that regulates the modification of synaptic structure and as a result regulates synaptic transmission.
98988	G-protein coupled glutamate receptor activity	F	Combining with glutamate and transmitting a signal from one side of the membrane to the other by activating an associated G-protein, initiating a change in cell activity.
98989	NMDA selective glutamate receptor signaling pathway	P	A series of molecular signals initiated by glutamate binding to an NMDA-selective glutamate receptor on the surface of the target cell, followed by the movement of ions through a channel in the receptor complex. Ends with regulation of a downstream cellular process, e.g. transcription.
98990	AMPA selective glutamate receptor signaling pathway	P	A series of molecular signals initiated by glutamate binding to an AMPA-selective glutamate receptor on the surface of the target cell, followed by the movement of ions through a channel in the receptor complex. Ends with regulation of a downstream cellular process, e.g. transcription.
98991	kainate selective glutamate receptor signaling pathway	P	A series of molecular signals initiated by glutamate binding to an kainate-selective glutamate receptor on the surface of the target cell, followed by the movement of ions through a channel in the receptor complex. Ends with regulation of a downstream cellular process, e.g. transcription.
98992	neuronal dense core vesicle	C	A dense core vesicle (granule) that is part of a neuron. These vesicles typically contain neuropeptides. They can be found in all parts of neurons, including the soma, dendrites, axonal swellings (varicosities) and synaptic terminals.
98993	anchored component of synaptic vesicle membrane	C	The component of the synaptic vesicle membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping.
98994	disruption of host cell envelope during viral entry	P	The disruption of host cell envelope by viral proteins during virus entry
98995	disruption by virus of host envelope lipopolysaccharide during virus entry	P	The breakdown of lipopolysaccharides in a host cell envelope during virus entry into a host cell. For example a phage entering a gram-negative bacterium may actively break down outer membrane lipopolysaccharides.
98996	disruption of host cell glycocalyx during viral entry	P	The disruption of host cell glycocalyx by viral proteins during virus entry
98997	fusion of virus membrane with host outer membrane	P	Fusion of a viral membrane with the host cell outer membrane during viral entry.
98998	extrinsic component of postsynaptic early endosome membrane	C	The component of the postsynaptic early endosome membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
98999	extrinsic component of postsynaptic endosome membrane	C	The component of the postsynaptic endosome membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
99000	viral genome ejection through host cell envelope, contractile tail mechanism	P	Ejection by a non-enveloped prokaryotic virus of its genome into the host cytoplasm via a contractile tail ejection system consisting of a baseplate, a central tube and an external contractile sheath. Upon binding to the host cell surface, the baseplate changes its conformation and triggers sheath contraction, driving the rigid internal tail tube through the cell envelope.
99001	viral genome ejection through host cell envelope, long flexible tail mechanism	P	Ejection by a non-enveloped prokaryotic virus of its genome into the host cytoplasm via a long, flexible tail ejection system consisting a baseplate, a central tube and a terminator complex which attaches the tail to the phage capsid. Upon binding to the host cell surface, the baseplate changes its conformation and triggers genome ejection into the host cell cytoplasm.
99002	viral genome ejection through host cell envelope, short tail mechanism	P	Ejection by a non-enveloped prokaryotic virus of its genome into the host cytoplasm via a short tail ejection system consisting a central tube, the connector which attaches the tail to the phage capsid and releases inner core proteins. Upon binding to the host cell surface, the phage displays a tube-like extension of its short tail that penetrates both host membranes. This tail extension comes from the release of viral core proteins with channel forming properties.
99003	vesicle-mediated transport in synapse	P	Any vesicle-mediated transport that occurs in a synapse
99004	calmodulin dependent kinase signaling pathway	P	Any signal transduction pathway involving calmodulin dependent kinase activity.
99005	extrinsic component of postsynaptic recycling endosome membrane	C	The component of the postsynaptic recycling endosome membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
99006	viral entry via permeabalization of endosomal membrane	P	The entry of a non-enveloped virus into a host eukaryotic cell, following endocytosis, via permeabalisation of the endosomal membrane by membrane penetration protein(s) associated with the viral capsid. In some cases, viral membrane-penetration protein require first to be activated to display its membrane penetrating activity. Activation can be due to receptor binding or the acidic pH of the endosomal lumen.
99007	extrinsic component of presynaptic endosome membrane	C	The component of the presynaptic endosome membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region.
99008	viral entry via permeabalization of inner membrane	P	The entry of a non-enveloped virus into the cytoplasm of a host prokaryotic cell, following fusion with the outer membrane, via permeabalisation of the plasma (inner) membrane. In the case of some double stranded RNA viruses of prokaryotes this occurs via interaction of a membrane-interacting component of the capsid, leading to depolarization an permeabalization of the plasma membrane.
99009	viral genome circularization	P	The circularization of a viral genome following infection of a host cell. This is common amongst bacterial viruses to protect the viral genome ends from nucleases, to convert the linear genome to an integrative precursor or to give rise to the replicative form of the genome. It can be mediated by covalent closure of the DNA sticky ends, recombinaison between redundant terminal sequences or via the binding of a protein at the viral DNA extremities
99010	modification of postsynaptic structure	P	Any process that modifies the structure of a postsynapse.
99011	neuronal dense core vesicle exocytosis	P	The secretion of molecules (e.g. neuropeptides, insulin-related peptides or neuromodulators such as serotonin and dopamine) contained within a neuronal dense core vesicle by fusion of the granule with the plasma membrane of a neuron in response to increased cytosolic calcium levels.
99012	neuronal dense core vesicle membrane	C	The lipid bilayer surrounding a neuronal dense core vesicle.
99013	neuronal dense core vesicle lumen	C	The volume enclosed by a neuronal dense core vesicle membrane.
99014	neuronal dense core vesicle organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a neuronal dense core vesicle.
99015	degradation of host chromosome by virus	P	The catabolic breakdown of the DNA of a host chromosome by a virus. This occurs during infection of bacteria by some phages. It frees up a large pool of nucleoside 5'-triphophates for use in viral DNA synthesis.
99016	DNA end degradation evasion by virus	P	Any process, either active or passive, by which a virus evades and ends degradation of its DNA when free viral-DNA ends are exposed as part of its life-cycle. For example, some bacteriophages encode proteins that bind to free viral DNA ends, protecting them from degradation by host exonucleases.
99017	maintenance of protein localization at cell tip	P	Any process in which localization of a protein is maintained at the cell tip.
99018	restriction-modification system evasion by virus	P	Any process, either active or passive, by which a virus evades the DNA restriction modification system of its host. Some viruses encode their own methyltransferase in order to protect their genome from host restriction enzymes. Others directly inhibit restruction enzymes while some use unusual bases in their genome to avoid restriction.
99019	maintenance of protein localization at growing cell tip	P	Any process in which localization of a protein is maintained at the growing cell tip.
99020	perinuclear endoplasmic reticulum lumen	C	The volume enclosed by the membranes of the perinuclear endoplasmic reticulum.
99021	cortical endoplasmic reticulum lumen	C	The volume enclosed by the membranes of the cortical endoplasmic reticulum.
99022	vesicle tethering	P	The initial, indirect interaction between a vesicle membrane and a membrane to which it is targeted for fusion. This interaction is mediated by tethering factors (or complexes), which interact with both membranes. Interaction can occur via direct binding to membrane phospholipids or membrane proteins, or via binding to vesicle coat proteins. This process is distinct from and prior to interaction between factors involved in fusion.
99023	tethering complex	C	Any protein complex that plays a role in vesicle tethering.
99024	plasma membrane invagination	P	An infolding of the plasma membrane.
99025	anchored component of postsynaptic membrane	C	The component of the postsynaptic membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping.
99026	anchored component of presynaptic membrane	C	The component of the presynaptic membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping.
99027	anchored component of presynaptic endocytic zone membrane	C	The component of the presynaptic endocytic zone membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping.
99028	anchored component of postynaptic endocytic zone membrane	C	The component of the postynaptic endocytic zone membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping.
99029	anchored component of presynaptic active zone membrane	C	The component of the presynaptic active zone membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping.
99030	anchored component of postsynaptic specialization membrane	C	The component of the postsynaptic specialization membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping.
99031	anchored component of postsynaptic density membrane	C	The component of the postsynaptic density membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping.
99032	anchored component of postsynaptic early endosome membrane	C	The component of the postsynaptic early endosome membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping.
99033	anchored component of postsynaptic recycling endosome membrane	C	The component of the postsynaptic recycling endosome membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping.
99034	anchored component of postsynaptic endosome membrane	C	The component of the postsynaptic endosome membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping.
99035	anchored component of spine apparatus membrane	C	The component of the spine apparatus membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping.
99036	anchored component of neuronal dense core vesicle membrane	C	The component of the neuronal dense core vesicle membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping.
99037	anchored component of presynaptic endosome membrane	C	The component of the presynaptic endosome membrane consisting of the gene products that are tethered to the membrane only by a covalently attached anchor, such as a lipid group that is embedded in the membrane. Gene products with peptide sequences that are embedded in the membrane are excluded from this grouping.
99038	ceramide-translocating ATPase activity	F	Catalysis of the movement of ceramide from one membrane bilayer leaflet to the other, driven by the hydrolysis of ATP.
99039	sphingolipid translocation	P	The movement of a sphingolipid molecule from one leaflet of a membrane bilayer to the opposite leaflet.
99040	ceramide translocation	P	The movement of a ceramide molecule from one leaflet of a membrane bilayer to the opposite leaflet.
99041	vesicle tethering to Golgi	P	The initial, indirect interaction between a transport vesicle membrane and the membrane of the Golgi. This interaction is mediated by tethering factors (or complexes), which interact with both membranes. Interaction can occur via direct binding to membrane phospholipids or membrane proteins, or via binding to vesicle coat proteins. This process is distinct from and prior fusion.
99042	nucleation of clathrin-coated pit	P	The first step in clathrin-dependent endocytosis: invagination of the plasma membrane to form a pit.
99043	cargo loading involved in clathrin-dependent endocytosis	P	Formation of a macromolecular complex during clathrin-dependent endocytosis that connects the assembling clathrin coat to the proteins and/or lipoproteins to be transported in an endocytic vesicle. This complex includes a receptor and an adaptor protein that links the receptor to the clathrin coat.
99044	vesicle tethering to endoplasmic reticulum	P	The initial, indirect interaction between a transport vesicle membrane and the membrane of the endoplasmic reticulum. This interaction is mediated by tethering factors (or complexes), which interact with both membranes. Interaction can occur via direct binding to membrane phospholipids or membrane proteins, or via binding to vesicle coat proteins. This process is distinct from and prior fusion.
99045	viral extrusion	P	The process whereby a filamentous phage particle is released from a bacterial host cell via a concerted mechanism of assembly and secretion. Neosynthesized virions are coordinately exported as they are assembled at the cell surface in a secretory process that leaves the host cell fully viable. Non-capsid proteins form structures that facilitate translocation through the inner membrane and outer membranes. A viral single-stranded DNA binding protein coats progeny viral DNA molecules to generate the intracellular precursor for assembly of phage particles as they are extruded through the membranes of the bacterial host. The structural proteins of the virus are anchored in the inner membrane before their incorporation into the phage particle. As assembly proceeds, the phage genome traverses the inner and outer membranes until the entire DNA molecule has been coated and extruded.
99046	clearance of foreign intracellular nucleic acids	P	A defense process that protects an organism from invading foreign DNA or RNA.
99047	clearance of foreign intracellular RNA	P	A defense process that protects an organism from invading foreign RNA.
99048	CRISPR-cas system	P	An adaptive immune response of bacteria that serves to clear host cells of foreign DNA and RNA. It has three distinct stage: acquisition of foreign DNA by integration into CRISPR loci in the host chromosome, CRISPR RNA (crRNA) biogenesis, and target interference. CISPR stands for Clustered Regularly Interspaced Short Palindromic Repeat, which describes the nature of the loci.
99049	clathrin coat assembly involved in endocytosis	P	The process that results in the assembly of clathrin triskelia into a clathrin cage during endocytosis. Clathrin is recruited to the plasma membrane via interaction with scaffolding proteins that bridge between clathtin and cell surface receptors. Clathrin coat formation is concomittant with coated pit formation leading to endocytic vesicle formation.
99050	vesicle scission	P	The membrane scission process that is the final step in the formation of a vesicle: separation from its parent membrane.
99051	vesicle scission involved in endocytosis	P	The membrane scission process that is the final step in the formation of an endocytic vesicle: separation from the plasma membrane.
99052	vesicle scission involved in clathrin-mediated endocytosis	P	The membrane scission process that is the final step in the formation of a clathrin-coated endocytic vesicle: separation from the plasma membrane.
99053	activating signal cointegrator 1 complex	C	A protein complex that contains TRIP4 (ASC1) and acts a transcriptional coactivator by interacting with transcription factors such as NF-kappa B. In humans this complex has 4 subunits: TRIP4 + ASCC1-3.
99054	presynapse assembly	P	The aggregation, arrangement and bonding together of a set of components to form a presynapse.
99055	integral component of postsynaptic membrane	C	The component of the postsynaptic membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
99056	integral component of presynaptic membrane	C	The component of the presynaptic membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
99057	integral component of presynaptic endocytic zone membrane	C	The component of the presynaptic endocytic zone membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
99058	integral component of postsynaptic endocytic zone membrane	C	The component of the postsynaptic endocytic zone membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
99059	integral component of presynaptic active zone membrane	C	The component of the presynaptic active zone membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
99060	integral component of postsynaptic specialization membrane	C	The component of the postsynaptic specialization membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
99061	integral component of postsynaptic density membrane	C	The component of the postsynaptic density membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
99062	integral component of postsynaptic early endosome membrane	C	The component of the postsynaptic early endosome membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
99063	integral component of postsynaptic recycling endosome membrane	C	The component of the postsynaptic recycling endosome membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
99064	integral component of postsynaptic endosome membrane	C	The component of the postsynaptic endosome membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
99065	integral component of spine apparatus membrane	C	The component of the spine apparatus membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
99066	integral component of neuronal dense core vesicle membrane	C	The component of the neuronal dense core vesicle membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
99067	integral component of presynaptic endosome membrane	C	The component of the presynaptic endosome membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
99068	postsynapse assembly	P	The aggregation, arrangement and bonding together of a set of components to form a postsynapse.
99069	synaptic vesicle tethering involved in synaptic vesicle exocytosis	P	The initial, indirect interaction between a synaptic vesicle membrane and a the preseynaptic membrane active zone. This interaction is mediated by tethering factors (or complexes), which interact with both membranes. This process is distinct from and prior to synaptic vesicle priming and fusion.
99070	static microtubule bundle	C	A microtubule bundle that has a constant length, and in which microtubule sliding does not take place.
99071	dynamic microtubule bundle	C	A microtubule bundle that undergoes changes in length, and in which microtubule sliding takes place.
99072	regulation of postsynaptic specialization membrane neurotransmitter receptor levels	P	Any process that regulates the the local concentration of neurotransmitter receptor at the postsynaptic specialization membrane.
99073	mitochondrion-derived vesicle	C	A vesicle derived via budding from a mitochondrion. These vesicles often contain inner membrane and, much more rarely, cristae.
99074	mitochondrion to lysosome transport	P	Transport from the mitochondrion to the lysosome, mediated by mitochondrion-derived vesicles
99075	mitochondrion-derived vesicle mediated transport	P	Transport from the mitochondrion, mediated by mitochondrion derived vesicles.
99076	mitochondrion to peroxisome transport	P	Transport from the mitochondrion to the peroxisome, mediated by mitochondrion-derived vesicles.
99077	histone-dependent DNA binding	F	DNA-binding activity that is dependent on binding to a histone.
99078	BORC complex	C	A protein complex that is invovled in positioning of the lysosome within the cytoplasm and which is composed of BLOC1S1, BLOC1S2, BORCS5, BORCS6, BORCS7, BORCS8, KXD1 and SNAPIN. The BORC complex recruits ARL8 at the cytosolic face of lysosomes and couples them to microtubule plus-end-directed kinesin motors.
99079	actin body	C	An amorphous cytoskeletal structure consisting of aggregated actin filaments and associated proteins (including fibrin and capping protein) in which there is little or no actin filament turnover. In yeast (S. pombe and S. cerevisiae) these are found only in quiescent cells and are thought to serve as a reserve store of actin.
99080	supramolecular complex	C	A cellular component that consists of an indeterminate number of proteins or macromolecular complexes, organized into a regular, higher-order structure such as a polymer, sheet, network or a fiber.
99081	supramolecular polymer	C	A polymeric supramolecular structure.
99082	retrograde trans-synaptic signaling by neuropeptide	P	Cell-cell signaling from postsynapse to presynapse, across the synaptic cleft, mediated by a neuropeptide.
99083	retrograde trans-synaptic signaling by neuropeptide, modulating synaptic transmission	P	Modulation of synaptic transmittion by cell-cell signaling across the synaptic cleft from postsynapse to presynapse, mediated by a neuropeptide.
99084	postsynaptic specialization organization	P	A process that results in the assembly, arrangement of constituent parts, or disassembly of a postsynaptic specialization, a structure that lies adjacent to the cytoplasmic face of the postsynaptic membrane.
99085	DIF dechlorinase activity	F	Catalysis of the reaction: 1-[(3,5-dichloro-2,6-dihydroxy-4-methoxy)phenyl]hexan-1-one => 1-[(3-chloro-2,6-dihydroxy-4-methoxy)phenyl]hexan-1-one + Cl-
99086	synaptonemal structure	C	
99087	anterograde axonal transport of messenger ribonucleoprotein complex	P	The directed movement of a messenger ribonucleoprotein complex along microtubules in axons, towards the presynapse.
99088	axonal transport of messenger ribonucleoprotein complex	P	The directed movement of a messenger ribonucleoprotein complex along microtubules in axons.
99089	establishment of endoplasmic reticulum localization to postsynapse	P	The directed movement of endoplasmic reticulum into a postsynaptic compartment such as a dendritic spine.
99090	recycling endosome localization within postsynapse	P	Any process in which a postsynaptic recycling endosome is transported from one location to another within the postsynapse or mainted in a specific location in the postsynapse.
99091	postsynaptic specialization, intracellular component	C	A network of proteins adjacent to the postsynaptic membrane. Its major components include the proteins that spatially and functionally organize neurotransmitter receptors in the membrane, such as anchoring and scaffolding molecules, signaling enzymes and cytoskeletal components.
99092	postsynaptic density, intracellular component	C	A network of proteins adjacent to the postsynaptic membrane forming an electron dense disc. Its major components include neurotransmitter receptors and the proteins that spatially and functionally organize neurotransmitter receptors in the membrane, such as anchoring and scaffolding molecules, signaling enzymes and cytoskeletal components.
99093	mitochondrial calcium release	P	A process in which a calcium ion (Ca2+) is transported from one side of a membrane to the other out of the mitochondrion by means of some agent such as a transporter or pore.
99094	ligand-gated cation channel activity	F	Enables the transmembrane transfer of an inorganic cation by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts.
99095	ligand-gated anion channel activity	F	Enables the transmembrane transfer of an inorganic anion by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts.
99096	vestibular calyx terminal	C	The giant, cup-shaped axon terminal of a vestibular afferent neuron, serving as a post-synaptic contact to a type I hair cell.
99097	prospore membrane biogenesis	P	A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a prospore membrane.
99098	microtubule polymerization based movement	P	The movement of a cellular component as a result of microtubule polymerization.
99099	G-protein gated ion channel activity	F	An ion channel activity that is gated by binding of a G-protein beta-gamma dimer.
99100	G-protein gated cation channel activity	F	A cation channel activity that is gated by binding of a G-protein beta-gamma dimer.
99101	G-protein gated potassium channel activity	F	A potassium channel activity that is gated by binding of a G-protein beta-gamma dimer.
99102	G-protein gated potassium channel activity involved in regulation of postsynaptic membrane potential	F	Any G-protein gated potassium channel activity that is involved regulation of postsynaptic membrane potential.
99103	channel activator activity	F	Direct interaction with a channel (binding or modification), resulting in its opening. A channel catalyzes energy-independent facilitated diffusion, mediated by passage of a solute through a transmembrane aqueous pore or channel.
99104	potassium channel activator activity	F	Direct interaction with a potassium channel (binding or modification), resulting in its opening.
99105	ion channel modulating, G-protein coupled receptor signaling pathway	P	The series of molecular signals generated as a consequence of a G-protein coupled receptor binding to its physiological ligand, where the pathway proceeds through activation or inhibition of an ion channel.
99106	ion channel regulator activity	F	Modulates the activity of a channel via direct interaction with it. A channel catalyzes energy-independent facilitated diffusion, mediated by passage of a solute through a transmembrane aqueous pore or channel.
99107	ion channel regulator activity involved in G-protein coupled receptor signaling pathway	F	Modulation of the activity of an ion channel via direct interaction with it as part of G-protein coupled receptor signaling.
99108	potassium channel activator activity involved in G-protein coupled receptor signaling pathway	F	Activation potassium ion channel activity via direct interaction with a potassium ion channel during G-protein coupled receptor signaling.
99109	potassium channel activating, G-protein coupled receptor signaling pathway	P	The series of molecular signals generated as a consequence of a G-protein coupled receptor binding to its physiological ligand, where the pathway proceeds activation of a potassium ion channel.
99110	microtubule polymerization based protein transport to cell tip cortex	P	The transport of a protein to the cortex of the cell tip, driven by polymerization of a microtubule to which the protein is attached.
99111	microtubule-based transport	P	A microtubule-based process that results in the transport of organelles, other microtubules, or other cellular components. Examples include motor-driven movement along microtubules and movement driven by polymerization or depolymerization of microtubules.
99112	microtubule polymerization based protein transport	P	The transport of a protein driven by polymerization of a microtubule to which it is attached.
99113	negative regulation of presynaptic cytosolic calcium concentration	P	Any process that decreases the concentration of calcium ions in the presynaptic cytosol.
99114	chromatin silencing at subtelomere	P	Repression of transcription of subtelomeric DNA by altering the structure of chromatin.
99115	chromosome, subtelomeric region	C	A heterochromatic region of the chromosome, adjacent to the telomere (on the centromeric side) that contains repetitive DNA and sometimes genes.
99116	tRNA 5'-end processing	P	The process in which the 5' end of a pre-tRNA molecule is converted to that of a mature tRNA.
99117	protein transport along microtubule to cell tip	P	The movement of a protein along a microtubule to the cell-tip, mediated by motor proteins.
99118	microtubule-based protein transport	P	A microtubule-based process that results in the transport of proteins.
99119	3-demethylubiquinone-8 3-O-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + 3-demethylubiquinone-8 = S-adenosyl-L-homocysteine + ubiquinone-8.
99120	colonial development	P	Development a structure consisting of multiple co-operating unicellular organisms of the same species. Examples include sorocarp development in Dictystelia and co-operative colonial structures formed by Myxococcus xanthus for the purpose of predation and fruiting body formation.
99121	fungal sorus development	P	The process whose specific outcome is the progression of a fungal sorus over time, from its formation to the mature structure. A fungal sorus is a spore containing structure.
99122	RNA polymerase II C-terminal domain binding	F	Interacting selectively and non-covalently with the C-terminal domain (CTD) of the largest subunit of RNA polymerase II. The CTD is comprised of repeats of a heptapeptide with the consensus sequence YSPTSPS. The number of repeats varies with the species and a minimum number of repeats is required for RNAP II function.
99123	somato-dendritic dopamine secretion	P	The regulated release of dopamine from the somatodendritic compartment (cell body or dendrites) of a neuron.
99124	axonal dopamine secretion	P	The regulated release of dopamine from an axon.
99125	PAK family kinase-Sog2 complex	C	A protein kinase complex comprising a conserved PAK/GC/Ste20 family kinase, leucine rich repeat protein Sog2 family, which function as part of the cell shape network.
99126	transforming growth factor beta complex	C	A protein complex acting as ligand of the transforming growth factor beta receptor complex, typically a homodimer of any of the TFGbeta isoforms. The precursor of TGFbeta proteins is cleaved into mature TGFbeta and the latency-associated peptide (LAP), which remains non-covalently linked to mature TGFbeta rendering it inactive. TGFbeta is activated by dimerisation and dissociation of the LAP.
99127	envenomation resulting in positive regulation of argininosuccinate synthase activity in other organism	P	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with the activation of the cytosolic argininosuccinate synthase in the bitten organism.
99128	mitochondrial iron-sulfur cluster assembly complex	C	A protein complex consisting of frataxin, cysteine desulfurase, an accessory protein and a Fe-S scaffold protein. In human these genes correspond to FXN, NFS1, ISD11 and ISCU respectively. This complex assembles Fe-S clusters onto the scaffolding protein using the substrates ferrous iron, electrons, and sulfur from l-cysteine.
99129	cochlear outer hair cell electromotile response	P	A rapid, force generating length change of an outer hair cell in response to electical stimulation. This occurs naturally as during hearing where it serves a source of mechanical amplification.
99130	estrogen binding	F	Interacting selectively and non-covalently with any estrogen.
99131	ATP hydrolysis coupled ion transmembrane transport	P	The transport of an inorganic ion across a membrane and against an electrochemical gradient, using energy from ATP hydrolysis.
99132	ATP hydrolysis coupled cation transmembrane transport	P	The transport of an inorganic cation across a membrane and against an electrochemical gradient, using energy from ATP hydrolysis.
99133	ATP hydrolysis coupled anion transmembrane transport	P	The transport of an inorganic anion across a membrane and against an electrochemical gradient, using energy from ATP hydrolysis.
99134	chimeric sorocarp development	P	Development of a sorocarp formed by aggregation of cells with different genotypes.
99135	chimeric colonial development	P	Development a structure consisting of multiple co-operating unicellular organisms of the same species, involving cells of more that one genotype.
99136	chimeric non-reproductive fruiting body development	P	Development of a non-reproductive fruiting body formed by aggregation of cells with different genotypes.
99137	altruistic, chimeric, non-reproductive fruiting body development	P	Development of a chimeric, non-reproductive fruiting body in which cells of all genotypes have an equal chance of becoming a spore cell.
99138	altruistic, chimeric sorocarp development	P	Development of a chimeric sorocarp in which cells of all genotypes have an equal chance of becoming a spore cell.
99139	cheating during chimeric sorocarp development	P	Any process during chimeric sorocarp development that increases by which a cell increases the number of spore cells sharing its genotype at the expense of cells of other genotypes.
99141	cellular response to protozoan	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a protozoan.
99142	intracellular ATP-gated ion channel activity	F	Enables the transmembrane transfer of an ion by a channel that opens when intracellular ATP has been bound by the channel complex or one of its constituent parts.
99400	caveola neck	C	A membrane microdomain that forms a necklace around the bulb (crater) of a caveola. Intramembrane particles are concentrated in this region and cytoskeletal components, including actin, are highly enriched in the area underlying it.
99401	caveola bulb	C	The region of a caveola that extends into the cytoplasm, excluding the neck (rim). This region is associated with intracellular caveola proteins.
99402	plant organ development	P	Development of a plant organ, a multi-tissue plant structure that forms a functional unit.
99403	maintenance of mitotic sister chromatid cohesion, telomeric	P	The process in which the association between sister chromatids of a replicated chromosome along the length of the telomeric region is maintained as chromosomes condense, attach to the spindle in a bipolar orientation, and congress to the metaphase plate during a mitotic cell cycle.
99404	mitotic sister chromatid cohesion, telomeric	P	The cell cycle process in which telomeres of sister chromatids are joined during mitosis.
99500	vesicle fusion to plasma membrane	P	Fusion of the membrane of a vesicle with the plasma membrane, thereby releasing its contents into the extracellular space.
99501	exocytic vesicle membrane	C	The lipid bilayer surrounding an exocytic vesicle
99502	calcium-dependent activation of synaptic vesicle fusion	P	The regulatory process by which increased cytosolic calcium levels lead to the the fusion of synaptic vesicles with the presynaptic active zone membrane by bringing primed synaptic vesicle membrane into contact with membrane presynaptic active zone membrane.
99503	secretory vesicle	C	A cytoplasmic, membrane bound vesicle that is capable of fusing to the plasma membrane to release its contents into the extracellular space.
99504	synaptic vesicle cycle	P	A biological process in which synaptic vesicles are loaded with neurotransmitters, move to the active zone, exocytose and are then recycled via endocytosis, ultimately leading to reloading with neurotransmitters.
99505	regulation of presynaptic membrane potential	P	Any process that modulates the potential difference across a presynaptic membrane.
99506	synaptic vesicle transport along actin filament	P	The directed movement of synaptic vesicles along actin filaments within a cell, powered by molecular motors.
99507	ligand-gated ion channel activity involved in regulation of presynaptic membrane potential	F	Any ligand-gated ion channel activity, occurring in the presynaptic membrane, that is involved in regulation of presynaptic membrane potential.
99508	voltage-gated ion channel activity involved in regulation of presynaptic membrane potential	F	Voltage-gated ion channel activity, occurring in the presynaptic membrane, involved in regulation of presynaptic membrane potential. This is a key step in synaptic transmission, following the arrival of an action potential at the synapse.
99509	regulation of presynaptic cytosolic calcium ion concentration	P	Any process that regulates the concentration of calcium in the presynaptic cytosol.
99510	calcium ion binding involved in regulation of cytosolic calcium ion concentration	F	The directed change of cytosolic calcium ion concentration in the cytosol via the reversible binding of calcium ions to calcium-binding proteins in the cytosol thereby modulating the spatial and temporal dynamics of changes in cytosolic calcium concentrations.
99511	voltage-gated calcium channel activity involved in regulation of cytosolic calcium levels	F	Regulation of cytosolic calcium ion concentrations via the directed movement of calcium ions across the plasma-membrane into the cytosol via the action of a voltage-gated calcium ion channel.
99512	supramolecular fiber	C	A polymer consisting of an indefinite number of protein or protein complex subunits that have polymerised to form a fiber-shaped structure.
99513	polymeric cytoskeletal fiber	C	A component of the cytoskeleton consisting of a homo or heteropolymeric fiber constructed from an indeterminate number of protein subunits.
99514	synaptic vesicle cytoskeletal transport	P	The directed movement of synaptic vesicles along cytoskeletal fibers such as microfilaments or microtubules within a cell, powered by molecular motors.
99515	actin filament-based transport	P	The transport of organelles or other particles from one location in the cell to another along actin filaments.
99516	ion antiporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ion A(out) + ion B(in) = ion A(in) + ion B(out) where ion A and ion B are different types of ion.
99517	synaptic vesicle transport along microtubule	P	The directed movement of synaptic vesicles along microtubules within a cell, powered by molecular motors.
99518	vesicle cytoskeletal trafficking	P	The directed movement of a vesicle along a cytoskeletal fiber such as a microtubule or and actin filament, mediated by motor proteins.
99519	dense core granule cytoskeletal transport	P	The directed movement of dense core granules along cytoskeletal fibers, such as microtubules or actin filaments.
99520	ion antiporter activity involved in regulation of presynaptic membrane potential	F	Any ion antiporter activity, occurring in the presynaptic membrane, that is involved in regulation of presynaptic membrane potential
99521	ATPase coupled ion transmembrane transporter activity involved in regulation of presynaptic membrane potential	F	Any ATPase coupled ion transmembrane transporter activity, occurring in the presynaptic membrane, that is involved in regulation of presynaptic membrane potential.
99522	region of cytosol	C	Any (proper) part of the cytosol of a single cell of sufficient size to still be considered cytosol
99523	presynaptic cytosol	C	The region of the cytosol consisting of all cytosol that is part of the presynapse.
99524	postsynaptic cytosol	C	The region of the cytosol consisting of all cytosol that is part of the postsynapse.
99525	presynaptic dense core vesicle exocytosis	P	The secretion of molecules (e.g. neuropeptides and neuromodulators such as serotonin and dopamine) contained within a membrane-bounced dense in response to increased presynaptic cytosolic calcium levels.
99526	presynapse to nucleus signaling pathway	P	A series of molecular signals that conveys information from the presynapse to the nucleus via cytoskeletal transport of a protein from a presynapse to the component to the nucleus where it affects biochemical processes that occur in the nucleus (e.g DNA transcription, mRNA splicing, or DNA/histone modifications).
99527	postsynapse to nucleus signaling pathway	P	A series of molecular signals that conveys information from the postsynapse to the nucleus via cytoskeletal transport of a protein from a postsynapse to the component to the nucleus where it affects biochemical processes that occur in the nucleus (e.g DNA transcription, mRNA splicing, or DNA/histone modifications).
99528	G-protein coupled neurotransmitter receptor activity	F	Combining with a neurotransmitter and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.
99529	neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential	F	Neurotransmitter receptor activity occurring in the postsynaptic membrane that is involved in regulating postsynaptic membrane potential, either directly (ionotropic receptors) or indirectly (e.g. via GPCR activation of an ion channel.)
99530	G-protein coupled receptor activity involved in regulation of postsynaptic membrane potential	F	G-protein coupled receptor activity occurring in the postsynaptic membrane that is part of a GPCR signaling pathway that positively regulates ion channel activity in the postsynaptic membrane.
99531	presynaptic process involved in chemical synaptic transmission	P	The pathway leading to secretion of a neurotransmitter from the presynapse as part of synaptic transmission.
99532	synaptic vesicle endosomal processing	P	The process in which synaptic vesicles fuse to the presynaptic endosome followed by sorting of synaptic vesicle components and budding of new synaptic vesicles.
99533	positive regulation of presynaptic cytosolic calcium concentration	P	Any process that increases the concentration of calcium ions in the presynaptic cytosol.
99534	calcium ion binding involved in regulation of presynaptic cytosolic calcium ion concentration	F	The directed change of presynaptic cytosolic free calcium ion concentration in the cytosol via the reversible binding of calcium ions to calcium-binding proteins in the cytosol thereby modulating the spatial and temporal dynamics of changes in presynaptic cytosolic calcium concentrations.
99535	synapse associated extracellular matrix	C	The extracellular matrix of the peri-synaptic space (the extracellular space adjacent to the synapse) and the synaptic cleft.
99536	synaptic signaling	P	Cell-cell signaling to or from a synapse.
99537	trans-synaptic signaling	P	Cell-cell signaling in either direction across the synaptic cleft.
99538	synaptic signaling via neuropeptide	P	Cell-cell signaling to or from a synapse, mediated by a peptide.
99539	neuropeptide secretion from presynapse	P	The secretion of neuropeptides contained within a dense core vesicle by fusion of the granule with the presynaptic membrane, stimulated by a rise in cytosolic calcium ion concentration.
99540	trans-synaptic signaling by neuropeptide	P	Cell-cell signaling between presynapse and postsynapse mediated by a peptide ligand crossing the synaptic cleft.
99541	trans-synaptic signaling by lipid	P	Cell-cell signaling from post to pre-synapse, across the synaptic cleft, mediated by a lipid.
99542	trans-synaptic signaling by endocannabinoid	P	Cell-cell signaling in either direction across the synaptic cleft, mediated by an endocannabinoid ligand.
99543	trans-synaptic signaling by soluble gas	P	Cell-cell signaling between presynapse and postsynapse mediated by a soluble gas ligand crossing the synaptic cleft.
99544	perisynaptic space	C	The extracellular region immediately adjacent to to a synapse.
99545	trans-synaptic signaling by trans-synaptic complex	P	Cell-cell signaling between presynapse and postsynapse mediated by a trans-synaptic protein complex.
99546	protein catabolic process, modulating synaptic transmission	P	Any catabolic process, occurring at a presynapse, that regulates synaptic transmission.
99547	regulation of translation at synapse, modulating synaptic transmission	P	Any process that modulates synaptic transmission by regulating translation occurring at the synapse.
99548	trans-synaptic signaling by nitric oxide	P	Cell-cell signaling between presynapse and postsynapse mediated by nitric oxide.
99549	trans-synaptic signaling by carbon monoxide	P	Cell-cell signaling between presynapse and postsynapse mediated by carbon monoxide.
99550	trans-synaptic signalling, modulating synaptic transmission	P	Cell-cell signaling between presynapse and postsynapse, across the synaptic cleft, that modulates the synaptic transmission properties of the synapse.
99551	trans-synaptic signaling by neuropeptide, modulating synaptic transmission	P	Cell-cell signaling between presynapse and postsynapse, via the vesicular release and reception of neuropeptide molecules, that modulates the synaptic transmission properties of the synapse.
99552	trans-synaptic signaling by lipid, modulating synaptic transmission	P	Cell-cell signaling between presynapse and postsynapse, via the release and reception of lipid molecules, that modulates the synaptic transmission properties of the synapse.
99553	trans-synaptic signaling by endocannabinoid, modulating synaptic transmission	P	Cell-cell signaling between presynapse and postsynapse, via the release and reception of endocannabinoid ligands, that modulates the synaptic transmission properties of the synapse.
99554	trans-synaptic signaling by soluble gas, modulating synaptic transmission	P	Cell-cell signaling between presynapse and postsynapse, via the release and reception of gaseous molecules, that modulates the synaptic transmission properties of the synapse.
99555	trans-synaptic signaling by nitric oxide, modulating synaptic transmission	P	Cell-cell signaling between presynapse and postsynapse, via the release and reception of nitric oxide molecules, that modulates the synaptic transmission properties of the synapse.
99556	trans-synaptic signaling by carbon monoxide, modulating synaptic transmission	P	Cell-cell signaling between presynapse and postsynapse, via the release and reception of carbon monoxide molecules, that modulates the synaptic transmission properties of the synapse.
99557	trans-synaptic signaling by trans-synaptic complex, modulating synaptic transmission	P	Cell-cell signaling between presynapse and postsynapse, mediated by transynaptic protein complexes, that modulates the synaptic transmission properties of the synapse.
99558	maintenance of synapse structure	P	A process that preserves the structural organistation and orientation of a synaptic cellular component such as the synaptic cytoskeleton and molecular scaffolds.
99559	maintenance of alignment of postsynaptic density and presynaptic active zone	P	The process by which alignment between postsynaptic density and presynaptic active zone is maintained.
99560	synaptic membrane adhesion	P	The attachment of presynaptic membrane to postsynaptic membrane via adhesion molecules that are at least partially embedded in the plasma membrane.
99561	synaptic membrane adhesion to extracellular matrix	P	The binding of a synaptic membrane to the extracellular matrix via adhesion molecules.
99562	maintenance of postsynaptic density structure	P	A process which maintains the organization and the arrangement of proteins in the presynaptic density.
99563	modification of synaptic structure	P	Any process that modifies the structure/morphology of a synapse.
99564	modification of synaptic structure, modulating synaptic transmission	P	Any process that modulates synaptic transmission via modification of the structure of the synapse.
99565	chemical synaptic transmission, postsynaptic	P	The part of synaptic transmission occurring in the post-synapse: a signal transduction pathway consisting of neurotransmitter receptor activation and its effects on postsynaptic membrane potential and the ionic composition of the postsynaptic cytosol.
99566	regulation of postsynaptic cytosolic calcium ion concentration	P	Any process that regulates the concentration of calcium in the postsynaptic cytosol.
99567	calcium ion binding involved in regulation of postsynaptic cytosolic calcium ion concentration	F	The directed change of free calcium ion concentration in the postsynaptic cytosol via the reversible binding of calcium ions to calcium-binding proteins in the cytosol thereby modulating the spatial and temporal dynamics of changes in postsynaptic cytosolic calcium concentrations.
99568	cytoplasmic region	C	Any (proper) part of the cytoplasm of a single cell of sufficient size to still be considered cytoplasm"
99569	presynaptic cytoskeleton	C	The portion of the cytoskeleton contained within the presynapse.
99571	postsynaptic cytoskeleton	C	The portion of the cytoskeleton contained within the postsynapse.
99572	postsynaptic specialization	C	A network of proteins within and adjacent to the postsynaptic membrane. Its major components include neurotransmitter receptors and the proteins that spatially and functionally organize them such as anchoring and scaffolding molecules, signaling enzymes and cytoskeletal components.
99573	glutamatergic postsynaptic density	C	The post-synaptic specialization of a glutamatergic excitatory synapse.
99574	regulation of protein catabolic process at synapse, modulating synaptic transmission	P	Any process that modulates synaptic transmission by regulating a catabolic process occurring at the synapse.
99575	regulation of protein catabolic process at presynapse, modulating synaptic transmission	P	Any process that modulates synaptic transmission by regulating a catabolic process occurring at a presynapse.
99576	regulation of protein catabolic process at postsynapse, modulating synaptic transmission	P	Any process that modulates synaptic transmission by regulating a catabolic process occurring at a postsynapse.
99577	regulation of translation at presynapse, modulating synaptic transmission	P	Any process that modulates synaptic transmission by regulating translation occurring at the presynapse.
99578	regulation of translation at postsynapse, modulating synaptic transmission	P	Any process that modulates synaptic transmission by regulating translation occurring at the postsynapse.
99579	G-protein coupled neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential	F	G-protein coupled neurotransmitter receptor activity, occurring in the postsynaptic membrane that involved in regulation of postsynaptic membrane potential.
99580	ion antiporter activity involved in regulation of postsynaptic membrane potential	F	Any ion antiporter activity, occurring in the postsynaptic membrane, that is involved in regulation of postsynaptic membrane potential
99581	ATPase coupled ion transmembrane transporter activity involved in regulation of postsynaptic membrane potential	F	Any ATPase coupled ion transmembrane transporter activity, occurring in the postsynaptic membrane, that is involved in regulation of postsynaptic membrane potential.
99582	neurotransmitter receptor activity involved in regulation of presynaptic cytosolic calcium ion concentration	F	Any neurotransmitter receptor activity that is involved in regulating the concentration of calcium in the presynaptic cytosol.
99583	neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration	F	Any neurotransmitter receptor activity that is involved in regulating the concentration of calcium in the postsynaptic cytosol.
99585	release of sequestered calcium ion into presynaptic cytosol	P	The process in which calcium ions sequestered in the endoplasmic reticulum, Golgi apparatus or mitochondria are released into the presynaptic cytosol.
99586	release of sequestered calcium ion into postsynaptic cytosol	P	The process in which calcium ions sequestered in the endoplasmic reticulum, Golgi apparatus or mitochondria are released into the postsynaptic cytosol.
99587	inorganic ion import into cell	P	The directed movement of inorganic ions from outside of a cell into the cytoplasmic compartment. This may occur via transport across the plasma membrane or via endocytosis.
99588	positive regulation of postsynaptic cytosolic calcium concentration	P	Any process that increases the concentration of calcium ions in the postsynaptic cytosol.
99589	serotonin receptor activity	F	Combining with the biogenic amine serotonin and transmitting a signal across a membrane by activating some effector activity. Serotonin (5-hydroxytryptamine) is a neurotransmitter and hormone found in vertebrates and invertebrates.
99590	neurotransmitter receptor internalization	P	A receptor-mediated endocytosis process that results in the internalization of a neurotransmitter receptor.
99592	endocytosed synaptic vesicle processing via endosome	P	The process in which endocytosed synaptic vesicles fuse to the presynaptic endosome followed by sorting of synaptic vesicle components and budding of new synaptic vesicles.
99593	endocytosed synaptic vesicle to endosome fusion	P	Fusion of an endocytosed synaptic vesicle with an endosome.
99600	transmembrane receptor activity	F	Combining with an extracellular or intracellular signal and transmitting a signal from one side of the membrane to the other.
99601	regulation of neurotransmitter receptor activity	P	Any process that modulates the frequency, rate or extent of neurotransmitter receptor activity. Modulation may be via an effect on ligand affinity, or effector funtion such as ion selectivity or pore opening/closing in ionotropic receptors.
99602	neurotransmitter receptor regulator activity	F	A molecular function that directly (via physical interaction or direct modification) activates, inhibits or otherwise modulates the activity of a neurotransmitter receptor. Modulation of activity includes changes in desensitization rate, ligand affinity, ion selectivity and pore-opening/closing.
99604	ligand-gated calcium channel activity	F	Enables the transmembrane transfer of a calcium ions by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts.
99605	regulation of action potential firing rate	P	Any process that regulates the frequency of action potentials in a spike train.
99606	microtubule plus-end directed mitotic chromosome migration	P	The cell cycle process in which chromosomes that are laterally attached to one or more mitotic spindle microtubules migrate towards the spindle equator via plus-end-directed movement along the microtubules. This process is part of mitotic metaphase plate congression.
99607	lateral attachment of mitotic spindle microtubules to kinetochore	P	The cell cycle process in which sister chromatids become laterally attached to spindle microtubules as part of mitotic metaphase plate congression. Attachment precedes migration along microtubules towards the spindle equator (metaphase plate).
99608	regulation of action potential firing pattern	P	Any process that regulates the temporal pattern of a sequence of action potentials in a neuron.
99609	microtubule lateral binding	F	Interacting selectively and non-covalently with the side of a microtubule.
99610	action potential initiation	P	The initiating cycle of an action potential. In vertebrate neurons this typically occurs at an axon hillock. Not all initiated axon potentials propagate.
99611	regulation of action potential firing threshold	P	Any process that regulates the potential at which an axon potential is triggered.
99612	protein localization to axon	P	A process in which a protein is transported to or maintained in a location within an axon.
99613	protein targeting to cell wall	P	The process of directing proteins towards the cell-wall.
99614	protein targeting to spore cell wall	P	The process of directing proteins towards the spore cell-wall.
99615	(D)-2-hydroxyglutarate-pyruvate transhydrogenase activity	F	Catalysis of the reaction: (R)-2-hydroxyglutarate + pyruvate = alpha-ketoglutarate + D-lactate, with FAD functioning as an intermediate hydrogen acceptor.
99616	extrinsic component of matrix side of mitochondrial inner membrane	C	The component of the matrix side of the mitochondrial inner membrane consisting of gene products and protein complexes that are loosely bound to one of its surfaces, but not integrated into the hydrophobic region."
99617	matrix side of mitochondrial inner membrane	C	The side (leaflet) of the mitochondrial inner membrane that faces the matrix.
99618	UDP-glucuronic acid dehydrogenase activity	F	Catalytis of the reaction: UDP-glucuronate + NAD+ = UDP-beta-L-threo-pentapyranos-4-ulose + CO2 + NADH + H+
99619	UDP-4-amino-4-deoxy-L-arabinose formyltransferase activity	F	Catalysis of the reaction: 10-formyltetrahydrofolate + UDP-4-amino-4-deoxy-beta-L-arabinopyranose = 5,6,7,8-tetrahydrofolate + UDP-4-deoxy-4-formamido-beta-L-arabinopyranose
99620	UDP-4-amino-4-deoxy-L-arabinose aminotransferase	F	Catalysis of the reaction: UDP-4-amino-4-deoxy-beta-L-arabinopyranose + 2-oxoglutarate = UDP-beta-L-threo-pentapyranos-4-ulose + L-glutamate
99621	undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase activity	F	Catalysis of the reaction: UDP-4-deoxy-4-formamido-beta-L-arabinopyranose + ditrans,octacis-undecaprenyl phosphate = UDP + 4-deoxy-4-formamido-alpha-L-arabinopyranosyl ditrans,octacis-undecaprenyl phosphate.
99622	cardiac muscle cell membrane repolarization	P	The process in which ions are transported across the plasma membrane of a cardiac muscle cell such that the membrane potential changes in the repolarizing direction, toward the steady state potential. For example, the repolarization during an action potential is from a positive membrane potential towards a negative resting potential.
99623	regulation of cardiac muscle cell membrane repolarization	P	Any process that modulates the establishment or extent of a change in membrane potential in the polarizing direction towards the resting potential in a cardiomyocyte.
99624	atrial cardiac muscle cell membrane repolarization	P	The process in which ions are transported across the plasma membrane of an atrial cardiac muscle cell such that the membrane potential changes in the repolarizing direction, toward the steady state potential. For example, the repolarization during an action potential is from a positive membrane potential towards a negative resting potential.
99625	ventricular cardiac muscle cell membrane repolarization	P	The process in which ions are transported across the plasma membrane of a ventricular cardiac muscle cell such that the membrane potential changes in the repolarizing direction, toward the steady state potential. For example, the repolarization during an action potential is from a positive membrane potential towards a negative resting potential.
99626	voltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels	F	Regulation of presynaptic cytosolic calcium ion concentrations via the action of voltage-gated calcium ion channels.
99627	neurotransmitter receptor cycle	P	The process during which neurotransmitter receptors, anchored in some region of the synaptic membrane, are recycled via the endosome. This cycle includes release from anchoring, diffusion in the synaptic membrane to an endocytic region, endocytosis, transport to the endosome, recycling in the endosome, transport back the synaptic membrane and subsequent anchoring (trapping).
99628	neurotransmitter receptor diffusion trapping	P	The process by which diffusing neurotransmitter receptor becomes trapped in region of the plasma membrane.
99629	postsynaptic specialization of symmetric synapse	C	A network of proteins, adjacent to the postsynaptic membrane of a symmetric synapse, consisting of anchoring and scaffolding molecules, signaling enzymes and cytoskeletal components that spatially and functionally organize the neurotransmitter receptors at the synapse. This structure is not as thick or electron dense as the postsynaptic densities found in asymmetric synapses.
99630	postsynaptic neurotransmitter receptor cycle	P	The process during which neurotransmitter receptors in the postsynaptic specialization membrane are recycled via the endosome. This cycle includes release from anchoring (trapping), diffusion in the synaptic membrane to the postsynaptic endocytic region, endocytosis, transport to the endosome, recycling in the endosome, transport back the synaptic membrane and subsequent trapping in the postsynaptic specialization membrane.
99631	postsynaptic endocytic zone cytoplasmic component	C	The cytoplasmic component of the postsynaptic endocytic zone.
99632	protein transport within plasma membrane	P	A process in which protein is transported from one region of the plasma membrane to another.
99633	protein localization to postsynaptic specialization membrane	P	A process in which a protein is transported to, or maintained in, a location within the membrane adjacent to a postsynaptic specialization (e.g. post synaptic density).
99634	postsynaptic specialization membrane	C	The membrane component of the postsynaptic specialization. This is the region of the postsynaptic membrane in which the population of neurotransmitter receptors involved in synaptic transmission are concentrated.
99635	voltage-gated calcium channel activity involved in positive regulation of presynaptic cytosolic calcium levels	F	Positive regulation of presynaptic cytosolic calcium ion concentrations via the directed movement of calcium ions across the plasma-membrane into the cytosol via the action of voltage-gated calcium ion channels. This is the first step in synaptic transmission
99636	cytoplasmic streaming	P	The directed flow of cytosol (the liquid component of the cytoplasm) and the organelles it contains.
99637	neurotransmitter receptor transport	P	The directed movement of neurotransmitter receptors.
99638	endosome to plasma membrane protein transport	P	The directed movement of proteins from the endosome to the plasma membrane in transport vesicles.
99639	neurotransmitter receptor transport, endosome to plasma membrane	P	The directed movement of neurotransmitter receptor from the endosome to the plasma membrane in transport vesicles.
99640	axo-dendritic protein transport	P	The directed movement of proteins along microtubules in neuron projections.
99641	anterograde axonal protein transport	P	The directed movement of proteins along microtubules from the cell body toward the cell periphery in nerve cell axons.
99642	retrograde axonal protein transport	P	The directed movement of proteins along microtubules from the cell periphery toward the cell body in nerve cell axons.
99643	signal release from synapse	P	Any signal release from a synapse.
99644	protein localization to presynaptic membrane	P	A process in which a protein is transported to, or maintained in, a location within a presynaptic membrane.
99645	neurotransmitter receptor localization to postsynaptic specialization membrane	P	A process in which a neurotransmitter is transported to, or maintained in, a location within the membrane adjacent to a postsynaptic specialization (e.g. postsynaptic density).
99646	neurotransmitter receptor transport, plasma membrane to endosome	P	Vesicle-mediated transport of a neurotransmitter receptor vesicle from the plasma membrane to the endosome.
99703	induction of synaptic vesicle exocytosis by positive regulation of presynaptic cytosolic calcium ion concentration	P	The induction of synaptic vesicle release by any process that leads to a rise in intracellular calcium ion concentration at the presynapse. This is the first step in synaptic transmission.
99738	cell cortex region	C	The complete extent of cell cortex that underlies some some region of the plasma membrane
100001	regulation of skeletal muscle contraction by action potential	P	Any action potential process that regulates skeletal muscle contraction
100002	negative regulation of protein kinase activity by protein phosphorylation	P	Any protein phosphorylation process that negatively_regulates protein kinase activity
100003	positive regulation of sodium ion transport by transcription from RNA polymerase II promoter	P	Any transcription from RNA polymerase II promoter process that positively_regulates sodium ion transport
100004	positive regulation of peroxisome organization by transcription from RNA polymerase II promoter	P	Any transcription from RNA polymerase II promoter process that positively_regulates peroxisome organization
100005	positive regulation of ethanol catabolic process by transcription from RNA polymerase II promoter	P	Any transcription from RNA polymerase II promoter process that positively_regulates ethanol catabolic process
100006	positive regulation of sulfite transport by transcription from RNA polymerase II promoter	P	Any transcription from RNA polymerase II promoter process that positively_regulates sulfite transport
100007	negative regulation of ceramide biosynthetic process by transcription from RNA polymerase II promoter	P	Any transcription from RNA polymerase II promoter process that negatively_regulates ceramide biosynthetic process
100008	regulation of fever generation by prostaglandin biosynthetic process	P	Any prostaglandin biosynthetic process process that regulates fever generation
100009	regulation of fever generation by prostaglandin secretion	P	Any prostaglandin secretion process that regulates fever generation
100010	positive regulation of fever generation by prostaglandin biosynthetic process	P	Any prostaglandin biosynthetic process process that positively_regulates fever generation
100011	positive regulation of fever generation by prostaglandin secretion	P	Any prostaglandin secretion process that positively_regulates fever generation
100012	regulation of heart induction by canonical Wnt signaling pathway	P	Any canonical Wnt signaling pathway process that regulates heart induction
100013	positive regulation of fatty acid beta-oxidation by transcription from RNA polymerase II promoter	P	Any transcription from RNA polymerase II promoter process that positively_regulates fatty acid beta-oxidation
100014	positive regulation of mating type switching by transcription from RNA polymerase II promoter	P	Any transcription from RNA polymerase II promoter process that positively_regulates mating type switching
100015	positive regulation of inositol biosynthetic process by transcription from RNA polymerase II promoter	P	Any transcription from RNA polymerase II promoter process that positively_regulates inositol biosynthetic process
100016	regulation of thiamine biosynthetic process by transcription from RNA polymerase II promoter	P	Any transcription from RNA polymerase II promoter process that regulates thiamine biosynthetic process
100017	negative regulation of cell-cell adhesion by transcription from RNA polymerase II promoter	P	Any transcription from RNA polymerase II promoter process that negatively_regulates single organismal cell-cell adhesion
100018	regulation of glucose import by transcription from RNA polymerase II promoter	P	Any transcription from RNA polymerase II promoter process that regulates glucose import
100019	regulation of cAMP-mediated signaling by transcription from RNA polymerase II promoter	P	Any transcription from RNA polymerase II promoter process that regulates cAMP-mediated signaling
100020	regulation of transport by transcription from RNA polymerase II promoter	P	Any transcription from RNA polymerase II promoter process that regulates transport
100021	regulation of iron ion transport by transcription from RNA polymerase II promoter	P	Any transcription from RNA polymerase II promoter process that regulates iron ion transport
100022	regulation of iron ion import by transcription from RNA polymerase II promoter	P	Any transcription from RNA polymerase II promoter process that regulates iron ion import
100023	regulation of meiotic nuclear division by transcription from RNA polymerase II promoter	P	Any transcription from RNA polymerase II promoter process that regulates meiotic nuclear division
100024	regulation of carbohydrate metabolic process by transcription from RNA polymerase II promoter	P	Any transcription from RNA polymerase II promoter process that regulates carbohydrate metabolic process
100025	negative regulation of cellular amino acid biosynthetic process by transcription from RNA polymerase II promoter	P	Any transcription from RNA polymerase II promoter process that negatively_regulates cellular amino acid biosynthetic process
100026	positive regulation of DNA repair by transcription from RNA polymerase II promoter	P	Any transcription from RNA polymerase II promoter process that positively_regulates DNA repair
100027	regulation of cell separation after cytokinesis by transcription from RNA polymerase II promoter	P	Any transcription from RNA polymerase II promoter process that regulates cell separation after cytokinesis
100028	regulation of conjugation with cellular fusion by transcription from RNA polymerase II promoter	P	Any transcription from RNA polymerase II promoter process that regulates conjugation with cellular fusion
100032	positive regulation of phospholipid biosynthetic process by transcription from RNA polymerase II promoter	P	Any transcription from RNA polymerase II promoter process that positively_regulates phospholipid biosynthetic process
100033	regulation of fungal-type cell wall biogenesis by transcription from RNA polymerase II promoter	P	Any transcription from RNA polymerase II promoter process that regulates fungal-type cell wall biogenesis
100034	regulation of 4,6-pyruvylated galactose residue biosynthetic process by transcription from RNA polymerase II promoter	P	Any transcription from RNA polymerase II promoter process that regulates 4,6-pyruvylated galactose residue biosynthetic process
100035	negative regulation of transmembrane transport by transcription from RNA polymerase II promoter	P	Any transcription from RNA polymerase II promoter process that negatively_regulates transmembrane transport
100036	positive regulation of purine nucleotide biosynthetic process by transcription from RNA polymerase II promoter	P	Any transcription from RNA polymerase II promoter process that positively_regulates purine nucleotide biosynthetic process
100037	positive regulation of cellular alcohol catabolic process by transcription from RNA polymerase II promoter	P	Any transcription from RNA polymerase II promoter process that positively_regulates cellular alcohol catabolic process
100038	regulation of cellular response to oxidative stress by transcription from RNA polymerase II promoter	P	Any transcription from RNA polymerase II promoter process that regulates cellular response to oxidative stress
100039	regulation of pyrimidine nucleotide biosynthetic process by transcription from RNA polymerase II promoter	P	Any transcription from RNA polymerase II promoter process that regulates pyrimidine nucleotide biosynthetic process
100040	negative regulation of invasive growth in response to glucose limitation by transcription from RNA polymerase II promoter	P	Any transcription from RNA polymerase II promoter process that negatively_regulates invasive growth in response to glucose limitation
100041	positive regulation of pseudohyphal growth by transcription from RNA polymerase II promoter	P	Any transcription from RNA polymerase II promoter process that positively_regulates pseudohyphal growth
100042	negative regulation of pseudohyphal growth by transcription from RNA polymerase II promoter	P	Any transcription from RNA polymerase II promoter process that negatively_regulates pseudohyphal growth
100043	negative regulation of cellular response to alkaline pH by transcription from RNA polymerase II promoter	P	Any transcription from RNA polymerase II promoter process that negatively_regulates cellular response to alkaline pH
100044	negative regulation of cellular hyperosmotic salinity response by transcription from RNA polymerase II promoter	P	Any transcription from RNA polymerase II promoter process that negatively_regulates cellular hyperosmotic salinity response
100045	negative regulation of arginine catabolic process by transcription from RNA polymerase II promoter	P	Any transcription from RNA polymerase II promoter process that negatively_regulates arginine catabolic process
100046	positive regulation of arginine biosynthetic process by transcription from RNA polymerase II promoter	P	Any transcription from RNA polymerase II promoter process that positively_regulates arginine biosynthetic process
100047	negative regulation of inositol biosynthetic process by transcription from RNA polymerase II promoter	P	Any transcription from RNA polymerase II promoter process that negatively_regulates inositol biosynthetic process
100048	positive regulation of phosphatidylcholine biosynthetic process by transcription from RNA polymerase II promoter	P	Any transcription from RNA polymerase II promoter process that positively_regulates phosphatidylcholine biosynthetic process
100049	negative regulation of phosphatidylcholine biosynthetic process by transcription from RNA polymerase II promoter	P	Any transcription from RNA polymerase II promoter process that negatively_regulates phosphatidylcholine biosynthetic process
100050	negative regulation of mating type switching by transcription from RNA polymerase II promoter	P	Any transcription from RNA polymerase II promoter process that negatively_regulates mating type switching
100051	positive regulation of meiotic nuclear division by transcription from RNA polymerase II promoter	P	Any transcription from RNA polymerase II promoter process that positively_regulates meiotic nuclear division
100052	negative regulation of G1/S transition of mitotic cell cycle by transcription from RNA polymerase II promoter	P	Any transcription from RNA polymerase II promoter process that negatively_regulates G1/S transition of mitotic cell cycle
100053	positive regulation of sulfate assimilation by transcription from RNA polymerase II promoter	P	Any transcription from RNA polymerase II promoter process that positively_regulates sulfate assimilation
100054	positive regulation of flocculation via cell wall protein-carbohydrate interaction by transcription from RNA polymerase II promoter	P	Any transcription from RNA polymerase II promoter process that positively_regulates flocculation via cell wall protein-carbohydrate interaction
100055	positive regulation of phosphatidylserine biosynthetic process by transcription from RNA polymerase II promoter	P	Any transcription from RNA polymerase II promoter process that positively_regulates phosphatidylserine biosynthetic process
100056	negative regulation of phosphatidylserine biosynthetic process by transcription from RNA polymerase II promoter	P	Any transcription from RNA polymerase II promoter process that negatively_regulates phosphatidylserine biosynthetic process
100057	regulation of phenotypic switching by transcription from RNA polymerase II promoter	P	Any transcription from RNA polymerase II promoter process that regulates phenotypic switching
100058	positive regulation of phenotypic switching by transcription from RNA polymerase II promoter	P	Any transcription from RNA polymerase II promoter process that positively_regulates phenotypic switching
100059	negative regulation of phenotypic switching by transcription from RNA polymerase II promoter	P	Any transcription from RNA polymerase II promoter process that negatively_regulates phenotypic switching
100060	negative regulation of SREBP signaling pathway by DNA binding	F	Any DNA binding that negatively_regulates SREBP signaling pathway
100061	negative regulation of SREBP signaling pathway by transcription factor catabolic process	P	Any transcription factor catabolic process process that negatively_regulates SREBP signaling pathway
100062	positive regulation of SREBP signaling pathway by transcription factor catabolic process	P	Any transcription factor catabolic process process that positively_regulates SREBP signaling pathway
100063	regulation of dipeptide transmembrane transport by transcription from RNA polymerase II promoter	P	Any transcription from RNA polymerase II promoter process that regulates dipeptide transmembrane transport
100064	negative regulation of filamentous growth of a population of unicellular organisms in response to starvation by transcription from RNA polymerase II promoter	P	Any transcription from RNA polymerase II promoter process that negatively_regulates filamentous growth of a population of unicellular organisms in response to starvation
100065	negative regulation of leucine import by transcription from RNA polymerase II promoter	P	Any transcription from RNA polymerase II promoter process that negatively_regulates leucine import
100066	negative regulation of induction of conjugation with cellular fusion by transcription from RNA polymerase II promoter	P	Any transcription from RNA polymerase II promoter process that negatively_regulates induction of conjugation with cellular fusion
100067	positive regulation of spinal cord association neuron differentiation by canonical Wnt signaling pathway	P	Any canonical Wnt signaling pathway process that positively_regulates spinal cord association neuron differentiation
100068	positive regulation of pyrimidine-containing compound salvage by transcription from RNA polymerase II promoter	P	Any transcription from RNA polymerase II promoter process that positively_regulates pyrimidine-containing compound salvage
100069	negative regulation of neuron apoptotic process by transcription from RNA polymerase II promoter	P	Any transcription from RNA polymerase II promoter process that negatively_regulates neuron apoptotic process
100070	regulation of fatty acid biosynthetic process by transcription from RNA polymerase II promoter	P	Any transcription from RNA polymerase II promoter process that regulates fatty acid biosynthetic process
101002	ficolin-1-rich granule	C	Highly exocytosable gelatinase-poor granules found in neutrophils and rich in ficolin-1. Ficolin-1 is released from neutrophil granules by stimulation with fMLP or PMA, and the majority becomes associated with the surface membrane of the cells and can be detected by flow cytometry.
101003	ficolin-1-rich granule membrane	C	The lipid bilayer surrounding a ficolin-1-rich granule.
101004	cytolytic granule membrane	C	The lipid bilayer surrounding the cytolytic granule.
101005	ubiquitinyl hydrolase activity	F	Catalysis of the hydrolysis of ubiquitin from proteins and other molecules.
101006	protein histidine phosphatase activity	F	Catalysis of the reaction: protein histidine phosphate + H2O = protein histidine + phosphate
101007	negative regulation of transcription from RNA polymerase II promoter in response to salt stress	P	Any process that decreases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating the organism is under salt stress. The stress is usually an increase or decrease in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment.
101008	negative regulation of transcription from RNA polymerase II promoter in response to increased salt	P	Any process that decreases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of detection of, or exposure to, an increase in the concentration of salt (particularly but not exclusively sodium and chloride ions) in the environment.
101010	pulmonary blood vessel remodeling	P	The reorganization or renovation of existing pulmonary blood vessels.
101011	inositol 1-diphosphate 2,3,4,5,6-pentakisphosphate 1-diphosphatase activity	F	Catalysis of the reaction: myo-inositol 1-diphosphate 2,3,4,5,6-pentakisphosphate + H2O = myo-inositol hexakisphosphate + phosphate.
101012	inositol 1,5-bisdiphosphate 2,3,4,6-tetrakisphosphate 1-diphosphatase activity	F	Catalysis of the reaction: myo-inositol 1,5-bisdiphosphate 2,3,4,6-tetrakisphosphate + H2O = myo-inositol 5-diphosphate 1,2,3,4,6-pentakisphosphate + phosphate.
101013	mechanically-modulated voltage-gated sodium channel activity	F	Enables the transmembrane transfer of a sodium ion by a voltage-gated channel whose activity is modulated in response to mechanical stress. Response to mechanical stress and voltage gating together is different than the sum of individual responses. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.
101014	[isocitrate dehydrogenase (NADP+)] phosphatase activity	F	Catalysis of the reaction: [isocitrate dehydrogenase] phosphate + H2O = [isocitrate dehydrogenase] + phosphate.
101016	FMN-binding domain binding	F	Interacting selectively and non-covalently with the FMN-binding domain of a protein.
101017	regulation of mitotic DNA replication initiation from late origin	P	Any process that modulates the frequency, rate or extent of firing from a late origin of replication involved in mitotic DNA replication.
101018	negative regulation of mitotic DNA replication initiation from late origin	P	Any process that stops, prevents or reduces the frequency, rate or extent of firing from a late origin of replication involved in mitotic DNA replication.
101019	nucleolar exosome (RNase complex)	C	A ribonuclease complex that has 3-prime to 5-prime distributive hydrolytic exoribonuclease activity and in some taxa (e.g. yeast) endoribonuclease activity, producing 5-prime-phosphomonoesters. Participates in a multitude of cellular RNA processing and degradation events preventing nuclear export and/or translation of aberrant RNAs. Restricted to processing linear and circular single-stranded RNAs (ssRNA) only. RNAs with complex secondary structures may have to be unwound or pre-processed by co-factors prior to entering the complex, esp if the 3-prime end is structured.
101020	estrogen 16-alpha-hydroxylase activity	F	Catalysis of the reaction: estrogen + donor-H2 + O2 = 16-alpha-hydroxyestrogen + H2O.
101021	estrogen 2-hydroxylase activity	F	Catalysis of the reaction: estrogen + donor-H2 + O2 = 2-hydroxyestrogen + H2O.
101023	vascular endothelial cell proliferation	P	The multiplication or reproduction of blood vessel endothelial cells, resulting in the expansion of a cell population.
101024	nuclear membrane organization involved in mitotic nuclear division	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the nuclear inner or outer membrane during mitotic nuclear division.
101025	nuclear membrane biogenesis	P	The process in which a nuclear membrane is synthesized, aggregates, and bonds together.
101026	nuclear membrane biogenesis involved in mitotic nuclear division	P	A process in which the nuclear inner or outer membrane is synthesized, aggregates, and bonds together during mitotic nuclear division.
101027	optical nerve axon regeneration	P	The regrowth of axons of the optical nerve following their loss or damage.
101028	positive regulation of liquid surface tension	P	Any process that activates or increases the surface tension of a liquid.
101029	negative regulation of liquid surface tension	P	Any process that prevents or reduces the surface tension of a liquid.
101030	tRNA-guanine transglycosylation	P	The modification of a tRNA anticodon loop by replacing guanine with queuonine. Reaction is tRNA guanine + queuine = tRNA queuine + guanine.
102001	isoleucine N-monooxygenase (oxime forming) activity	F	Catalysis of the reaction: L-isoleucine + 2 O2 + 2 NADPH(4-) + 2 H+ <=> (E)-2-methylbutanal oxime + 2 NADP(3-) + carbon dioxide + 3 H2O.
102002	valine N-monooxygenase (oxime forming) activity	F	Catalysis of the reaction: L-valine + 2 O2 + 2 NADPH(4-) + 2 H+ <=> (E)-2-methylpropanal oxime + 2 NADP(3-) + carbon dioxide + 3 H2O.
102003	Delta8-sphingolipid desaturase activity	F	Catalysis of the reaction: phytosphingosine(1+) + O2 + a reduced electron acceptor <=> 4-hydroxy-trans-8-sphingenine + 2 H2O + an oxidized electron acceptor.
102004	2-octaprenyl-6-hydroxyphenol methylase activity	F	Catalysis of the reaction: 3-(all-trans-octaprenyl)benzene-1,2-diol + S-adenosyl-L-methionine <=> H+ + 2-methoxy-6-(all-trans-octaprenyl)phenol + S-adenosyl-L-homocysteine.
102005	2-octaprenyl-6-methoxy-1,4-benzoquinone methylase activity	F	Catalysis of the reaction: 6-methoxy-2-octaprenylhydroquinone + S-adenosyl-L-methionine <=> H+ + S-adenosyl-L-homocysteine + 5-methoxy-2-methyl-3-octaprenylhydroquinone.
102006	4-methyl-2-oxopentanoate dehydrogenase activity	F	Catalysis of the reaction: 4-methyl-2-oxopentanoate + coenzyme A(4-) + NAD(1-) <=> isovaleryl-CoA(4-) + carbon dioxide + NADH(2-).
102007	acyl-L-homoserine-lactone lactonohydrolase activity	F	Catalysis of the reaction: H2O + an N-acyl-L-homoserine lactone <=> H+ + an N-acyl-L-homoserine.
102008	cytosolic dipeptidase activity	F	Catalysis of the reaction: H2O + a dipeptide <=> 2 a standard alpha amino acid that occurs in the cytosol
102009	proline dipeptidase activity	F	Catalysis of the reaction: H2O + a dipeptide with proline at the C-terminal <=> L-proline + a standard alpha amino acid.
102013	L-glutamate-importing ATPase activity	F	Catalysis of the reaction: ATP(4-) + L-glutamate(1-) + H2O <=> ADP(3-) + hydrogenphosphate + L-glutamate(1-) + H+.
102014	beta-D-galactose-importing ATPase activity	F	Catalysis of the reaction: ATP(4-) + beta-D-galactoside + H2O <=> ADP(3-) + hydrogenphosphate + beta-D-galactoside + H+.
102017	ATPase-coupled alkylphosphonate transmembrane transporter activity	F	Catalysis of the reaction: ATP(4-) + H2O + an alkylphosphonate <=> ADP(3-) + hydrogenphosphate + H+ + an alkylphosphonate.
102022	L-arginine-importing ATPase activity	F	Catalysis of the reaction: ATP(4-) + L-argininium(1+) + H2O <=> ADP(3-) + hydrogenphosphate + L-argininium(1+) + H+.
102027	S-adenosylmethionine:2-demethylquinol-8 methyltransferase activity	F	Catalysis of the reaction: 2-demethylmenaquinol-8 + S-adenosyl-L-methionine <=> menaquinol-8 + H+ + S-adenosyl-L-homocysteine.
102030	dTDP-L-rhamnose synthetase activity	F	Catalysis of the reaction: dTDP-6-deoxy-beta-L-mannose + NAD+ <=> dTDP-4-dehydro-6-deoxy-alpha-D-glucose + NADH + H+
102031	4-acetamido-4,6-dideoxy-D-galactose transferase activity	F	Catalysis of the reaction: dTDP-4-acetamido-4,6-dideoxy-alpha-D-galactose + beta-D-ManNAcA-(1->4)-alpha-D-GlcNAc-1-diphospho-ditrans,polycis-undecaprenol <=> H+ + alpha-D-FucNAc4-(1->4)-beta-D-ManNAcA-(1->4)-D-GlcNAc-undecaprenyl diphosphate + dTDP
102033	cytochrome P450 fatty acid omega-hydroxylase activity	F	Catalysis of the reaction: linoleoyl-CoA(4-) + H2O <=> H+ + linoleate + coenzyme A
102035	isobutyryl-CoA:FAD oxidoreductase activity	F	Catalysis of the reaction: H+ + isobutyryl-CoA + FAD <=> methacrylyl-CoA + FADH2
102036	methyltetrahydrofolate:corrinoid/iron-sulfur protein methyltransferase activity	F	Catalysis of the reaction: a tetrahydrofolate + a [methyl-Co(III) corrinoid Fe-S protein] <=> an N5-methyl-tetrahydrofolate + a [Co(I) corrinoid Fe-S protein]
102037	4-nitrotoluene monooxygenase activity	F	Catalysis of the reaction: H+ + 4-nitrotoluene + NADH + O2 <=> 4-nitrobenzyl alcohol + NAD+ + H2O
102039	alkylhydroperoxide reductase activity	F	Catalysis of the reaction: H2O + NAD + an alcohol <=> NADH + H+ + an organic hydroperoxide
102043	isopentenyl phosphate kinase activity	F	Catalysis of the reaction: isopentenyl phosphate(2-) + ATP(4-) <=> isopentenyl diphosphate(3-) + ADP(3-)
102044	3-chlorobenzoate-4,5-oxygenase activity	F	Catalysis of the reaction: 3-chlorobenzoate + O2 + a reduced electron acceptor <=> 3-chlorobenzoate-cis-4,5-diol + an oxidized electron acceptor
102045	3-chlorobenzoate-3,4-oxygenase activity	F	Catalysis of the reaction: 3-chlorobenzoate + O2 + a reduced electron acceptor <=> 3-chlorobenzoate-cis-3,4-diol + an oxidized electron acceptor
102046	3,4-dichlorobenzoate-4,5-oxygenase activity	F	Catalysis of the reaction: 3,4-dichlorobenzoate + O2 + a reduced electron acceptor <=> 3,4-dichlorobenzoate-cis-4,5-diol + an oxidized electron acceptor
102047	indole-3-acetyl-glycine synthetase activity	F	Catalysis of the reaction: indole-3-acetate + glycine + ATP(4-) <=> H+ + indole-3-acetyl-glycine + AMP(2-) + diphosphoric acid
102048	indole-3-acetyl-isoleucine synthetase activity	F	Catalysis of the reaction: indole-3-acetate + L-isoleucine + ATP(4-) <=> H+ + indole-3-acetyl-isoleucine + AMP(2-) + diphosphoric acid
102049	indole-3-acetyl-methionine synthetase activity	F	Catalysis of the reaction: indole-3-acetate + L-methionine + ATP(4-) <=> H+ + indole-3-acetyl-methionine + AMP(2-) + diphosphoric acid
102050	indole-3-acetyl-tyrosine synthetase activity	F	Catalysis of the reaction: indole-3-acetate + L-tyrosine + ATP(4-) <=> H+ + indole-3-acetyl-tyrosine + AMP(2-) + diphosphoric acid
102051	indole-3-acetyl-tryptophan synthetase activity	F	Catalysis of the reaction: indole-3-acetate + L-tryptophan + ATP(4-) <=> H+ + indole-3-acetyl-tryptophan + AMP(2-) + diphosphoric acid
102052	indole-3-acetyl-proline synthetase activity	F	Catalysis of the reaction: indole-3-acetate + L-proline + ATP(4-) <=> H+ + indole-3-acetyl-proline + AMP(2-) + diphosphoric acid
102053	(-)-jasmonoyl-isoleucine synthetase activity	F	Catalysis of the reaction: (-)-jasmonate + L-isoleucine + ATP(4-) <=> H+ + (-)-jasmonoyl-L-isoleucine + AMP(2-) + diphosphoric acid
102054	maleylpyruvate hydrolase activity	F	Catalysis of the reaction: 3-maleylpyruvate(2-) + H2O <=> H+ + maleate(2-) + pyruvate
102055	12-hydroxyjasmonate sulfotransferase activity	F	Catalysis of the reaction: 3'-phosphonato-5'-adenylyl sulfate + a 12-hydroxyjasmonate <=> adenosine 3',5'-bismonophosphate + a 12-hydroxyjasmonate sulfate
102056	11-hydroxyjasmonate sulfotransferase activity	F	Catalysis of the reaction: 3'-phosphonato-5'-adenylyl sulfate + an 11-hydroxyjasmonate <=> adenosine 3',5'-bismonophosphate + H+ + an 11-hydroxyjasmonate sulfate
102057	jasmonoyl-valine synthetase activity	F	Catalysis of the reaction: L-valine + ATP(4-) + a jasmonic acid <=> AMP(2-) + diphosphoric acid + a jasmonoyl-valine
102058	jasmonoyl-leucine synthetase activity	F	Catalysis of the reaction: L-leucine + ATP(4-) + a jasmonic acid <=> AMP(2-) + diphosphoric acid + a jasmonoyl-leucine
102060	endo-alpha-bergamontene synthase activity	F	Catalysis of the reaction: 2-cis,6-cis-farnesyl diphosphate <=> (-)-endo-alpha-bergamotene + diphosphoric acid
102061	endo-beta-bergamontene synthase activity	F	Catalysis of the reaction: 2-cis,6-cis-farnesyl diphosphate <=> (+)-endo-beta-bergamotene + diphosphoric acid
102062	alpha-santalene synthase activity	F	Catalysis of the reaction: 2-cis,6-cis-farnesyl diphosphate <=> (+)-alpha-santalene + diphosphoric acid
102063	beta-curcumene synthase activity	F	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate(3-) <=> diphosphoric acid + (-)-beta-curcumene
102064	gamma-curcumene synthase activity	F	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate <=> gamma-curcumene + diphosphoric acid
102065	patchoulene synthase activity	F	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate <=> diphosphoric acid + gamma-patchoulene
102068	alpha-humulene 10-hydroxylase activity	F	Catalysis of the reaction: (1E,4E,8E)-alpha-humulene + NADPH + O2 + H+ <=> 8-hydroxy-alpha-humulene + NADP + H2O
102069	zerumbone synthase activity	F	Catalysis of the reaction: 8-hydroxy-alpha-humulene + NAD <=> zerumbone + NADH + H+
102077	oleamide hydrolase activity	F	Catalysis of the reaction: oleamide + H2O <=> oleate + ammonium
102078	methyl jasmonate methylesterase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + a jasmonic acid <=> S-adenosyl-L-homocysteine + a methyl jasmonate
102081	homotaurine:2-oxoglutarate aminotransferase activity	F	Catalysis of the reaction: homotaurine + 2-oxoglutarate(2-) <=> 3-sulfopropanal + L-glutamate(1-)
102082	demethylrebeccamycin--D-glucose O-methyltransferase activity	F	Catalysis of the reaction: 4'-demethylrebeccamycin + S-adenosyl-L-methionine <=> H+ + rebeccamycin + S-adenosyl-L-homocysteine
102083	7,8-dihydromonapterin aldolase activity	F	Catalysis of the reaction: 7,8-dihydromonapterin <=> glycolaldehyde + 2-amino-6-(hydroxymethyl)-7,8-dihydropteridin-4-ol
102086	N-vanillate-L-glutamate synthetase activity	F	Catalysis of the reaction: vanillate + L-glutamate(1-) + ATP <=> H+ + N-vanillate-L-glutamate + AMP + diphosphoric acid
102097	(22S)-22-hydroxy-5alpha-campestan-3-one C-23 hydroxylase activity	F	Catalysis of the reaction: (5alpha,22S,24R)-22-hydroxyergostan-3-one + O2 + NADPH + H+ <=> 3-dehydro-6-deoxoteasterone + NADP + H2O
102100	mycothiol-arsenate ligase activity	F	Catalysis of the reaction: arsenate + mycothiol <=> mycothiol-arsenate conjugate + H2O
102103	bisdemethoxycurcumin syntase activity	F	Catalysis of the reaction: (4-coumaroyl)acetyl-CoA + 4-coumaryl-CoA + H2O <=> bisdemethoxycurcumin + 2 coenzyme A + carbon dioxide
102104	demethoxycurcumin synthase activity	F	Catalysis of the reaction: (4-coumaroyl)acetyl-CoA(4-) + feruloyl-CoA + H2O <=> demethoxycurcumin + 2 coenzyme A + carbon dioxide
102109	tricaffeoyl spermidine O-methyltransferase activity	F	Catalysis of the reaction: tricaffeoyl spermidine + 3 S-adenosyl-L-methionine <=> 3 H+ + triferuloyl spermidine + 3 S-adenosyl-L-homocysteine
102117	gibberellin A9 carboxyl methyltransferase activity	F	Catalysis of the reaction: gibberellin A9 + S-adenosyl-L-methionine <=> gibberellin A9 methyl ester + S-adenosyl-L-homocysteine
102118	gibberellin A4 carboxyl methyltransferase activity	F	Catalysis of the reaction: gibberellin A4 + S-adenosyl-L-methionine <=> gibberellin A4 methyl ester + S-adenosyl-L-homocysteine
102119	gibberellin A20 carboxyl methyltransferase activity	F	Catalysis of the reaction: gibberellin A20 + S-adenosyl-L-methionine <=> gibberellin A20 methyl ester + S-adenosyl-L-homocysteine
102126	coniferyl aldehyde 5-hydroxylase activity	F	Catalysis of the reaction: H+ + coniferyl aldehyde + NADPH + O2 <=> 5-hydroxy-coniferaldehyde + NADP + H2O
102132	3-oxo-pimeloyl-[acp] methyl ester reductase activity	F	Catalysis of the reaction: NADP + a 3R-hydroxypimeloyl-[acp] methyl ester <=> NADPH + H+ + a 3-oxo-pimeloyl-[acp] methyl ester.
102133	limonene hydroxylase activity	F	Catalysis of the reaction: (4R)-limonene + O2 + NADH + H+ <=> (4R)-perillyl alcohol + NAD + H2O.
102134	(22S)-22-hydroxy-campesterol C-23 hydroxylase activity	F	Catalysis of the reaction: H+ + (22S)-22-hydroxycampesterol + NADPH + O2 <=> (22R,23R)-22,23-dihydroxycampesterol + NADP + H2O.
102135	(22S)-22-hydroxy-campest-4-en-3-one C-23 hydroxylase activity	F	Catalysis of the reaction: H+ + (22S)-22-hydroxycampest-4-en-3-one + NADPH + O2 <=> (22R,23R)-22,23-dihydroxy-campest-4-en-3-one + NADP + H2O.
102136	3-epi-6-deoxocathasterone C-23 hydroxylase activity	F	Catalysis of the reaction: H+ + 3-epi-6-deoxocathasterone + NADPH + O2 <=> 6-deoxotyphasterol + NADP + H2O.
102137	7-oxateasterone synthase activity	F	Catalysis of the reaction: H+ + teasterone + NADPH + O2 <=> 7-oxateasterone + NADP + H2O.
102138	7-oxatyphasterol synthase activity	F	Catalysis of the reaction: H+ + typhasterol + NADPH + O2 <=> 7-oxatyphasterol + NADP + H2O
102139	2-hydroxy-6-oxo-6-(2'-aminophenyl)-hexa-2,4dienoate hydrolase activity	F	Catalysis of the reaction: (2E,4E)-6-(2-aminophenyl)-2-hydroxy-6-oxohexa-2,4-dienoate + H2O <=> H+ + anthranilate + (2E)-2-hydroxypenta-2,4-dienoate.
102145	(3R)-(E)-nerolidol synthase activity	F	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate + H2O <=> (3R,6E)-nerolidol + diphosphoric acid
102154	8C-naringenin dibenzoylmethane tautomer glucosyltransferase activity	F	Catalysis of the reaction: 2,4,4',6-tetrahydroxydibenzoylmethane + UDP-alpha-D-glucose <=> 8C-glucosyl-2-hydroxynaringenin + UDP + 2 H+
102155	S-sulfolactate dehydrogenase activity	F	Catalysis of the reaction: (S)-3-sulfonatolactate + NAD <=> 3-sulfonatopyruvate(2-) + NADH + H+
102156	2,5-DHBA UDP-glucosyltransferase activity	F	Catalysis of the reaction: 2,5-dihydroxybenzoate + UDP-alpha-D-glucose <=> 2,5-dihydroxybenzoate 5-O-beta-D-glucoside + UDP + H+
102157	(R)-sulfopropanediol 2-dehydrogenase activity	F	Catalysis of the reaction: (2R)-3-sulfopropanediol(1-) + NAD <=> 2-oxo-3-hydroxy-propane-1-sulfonate + NADH + H+
102159	baicalein 7-O-glucuronosyltransferase activity	F	Catalysis of the reaction: UDP-alpha-D-glucuronate + baicalein <=> H+ + UDP + baicalin
102160	cyanidin-3-O-glucoside 2-O-glucuronosyltransferase activity	F	Catalysis of the reaction: cyanidin 3-O-beta-D-glucoside betaine + UDP-alpha-D-glucuronate <=> H+ + cyanidin 3-O-beta-(2-O-beta-D-glucuronosyl)-beta-D-glucoside + UDP
102161	copal-8-ol diphosphate synthase activity	F	Catalysis of the reaction: copal-8-ol diphosphate <=> 2-trans,6-trans,10-trans-geranylgeranyl diphosphate + H2O
102162	<em>all</em>-<em>trans</em>-8prime-apo-beta-carotenal 15,15prime-oxygenase activity	F	Catalysis of the reaction: 8'-apo-beta,psi-caroten-8'-al + O2 <=> all-trans-retinal + 2,6-dimethylocta-2,4,6-trienedial
102168	5-methyl-phenazine-1-carboxylate N-methyltransferase activity	F	Catalysis of the reaction: phenazine-1-carboxylate + S-adenosyl-L-methionine <=> 5-methylphenazine-1-carboxylate + S-adenosyl-L-homocysteine
102169	pyocyanin hydroxylase activity	F	Catalysis of the reaction: 5-methylphenazine-1-carboxylate + NADH + O2 + 2 H+ <=> pyocyanin + NAD + carbon dioxide + H2O
102171	DMNT synthase activity	F	Catalysis of the reaction: H+ + (3S,6E)-nerolidol + NADPH + O2 <=> (E)-4,8-dimethyl-1,3,7-nonatriene + buten-2-one + NADP + 2 H2O
102173	24-methylenecycloartanol 4alpha-methyl oxidase activity	F	Catalysis of the reaction: 24-methylenecycloartanol + NADH + O2 + H+ <=> 4alpha-hydroxymethyl,4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-ergost-24(241)-en-3beta-ol + NAD + H2O
102176	cycloeucalenone reductase activity	F	Catalysis of the reaction: cycloeucalenone + NADPH + H+ <=> cycloeucalenol + NADP
102177	24-methylenelophenol methyl oxidase activity	F	Catalysis of the reaction: 24-methylenelophenol + O2 + NADH + H+ <=> 4alpha-hydroxymethyl-ergosta-7,24(241)-dien-3beta-ol + NAD + H2O
102178	4alpha-formyl-ergosta-7,24(241)-dien-3beta-ol-methyl oxidase activity	F	Catalysis of the reaction: 4alpha-formyl-ergosta-7,24(241)-dien-3beta-ol + O2 + NADH <=> 4alpha-carboxy-ergosta-7,24(241)-dien-3beta-ol + NAD + H2O
102180	4alpha-hydroxymethyl-stigmasta-7,24(241)-dien-3beta-ol-methyl oxidase activity	F	Catalysis of the reaction: 4alpha-hydroxymethyl-stigmasta-7,24(241)-dien-3beta-ol + NADH + O2 + H+ <=> 4alpha-formyl-stigmasta-7,24(241)-dien-3beta-ol + NAD + 2 H2O
102181	4alpha-formyl-stigmasta-7,24(241)-dien-3beta-ol-methyl oxidase activity	F	Catalysis of the reaction: 4alpha-formyl-stigmasta-7,24(241)-dien-3beta-ol + NADH + O2 <=> 4alpha-carboxy-stigmasta-7,24(241)-dien-3beta-ol + NAD + H2O
102182	4alpha-carboxy-stigmasta-7,24(241)-dien-3beta-ol dehydrogenase/C4-decarboxylase activity	F	Catalysis of the reaction: 4alpha-carboxy-stigmasta-7,24(241)-dien-3beta-ol + NAD <=> avenastenone + NADH + carbon dioxide
102183	avenastenone reductase activity	F	Catalysis of the reaction: avenastenone + NADPH + H+ <=> avenasterol + NADP
102184	cycloartenol 4alpha-methyl oxidase activity	F	Catalysis of the reaction: cycloartenol + NADH + O2 + H+ <=> 4alpha-hydroxymethyl,4beta,14alpha-dimethyl-9beta,19-cyclo-5alpha-cholest-24-en-3beta-ol + NAD + H2O
102193	protein-ribulosamine 3-kinase activity	F	Catalysis of the reaction: ATP + a [protein]-N6-D-ribulosyl-L-lysine <=> ADP + a [protein]-N6-(3-O-phospho-D-ribulosyl)-L-lysine
102194	protein-fructosamine 3-kinase activity	F	Catalysis of the reaction: ATP + a [protein]-N6-D-fructosyl-L-lysine <=> ADP + H+ + a [protein]-N6-(3-O-phospho-D-fructosyl)-L-lysine
102197	vinylacetate caboxylester hydrolase activity	F	Catalysis of the reaction: but-3-enoate + H2O <=> allyl alcohol + formate
102201	(+)-2-epi-prezizaene synthase activity	F	Catalysis of the reaction: 2-cis,6-trans-farnesyl diphosphate <=> (+)-2-epi-prezizaene + diphosphoric acid
102202	soladodine glucosyltransferase activity	F	Catalysis of the reaction: UDP-alpha-D-glucose + solasodine <=> UDP + solasodine 3-O-beta-D-glucopyranoside + H+
102203	brassicasterol glucosyltransferase activity	F	Catalysis of the reaction: UDP-alpha-D-glucose + brassicasterol <=> UDP(3-) + 3-O-beta-D-glucosyl-brassicasterol + H+
102209	trans-permethrin hydrolase activity	F	Catalysis of the reaction: (-)-trans-permethrin + H2O <=> H+ + (3-phenoxyphenyl)methanol + (1S,3R)-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate
102210	rhamnogalacturonan endolyase activity	F	Catalysis of the reaction: H2O + a rhamnogalacturonan type I <=> [rhamnogalacturonan I oligosaccharide]-alpha-L-rhamnose + 4-deoxy-4,5-unsaturated D-galactopyranosyluronate-[rhamnogalacturonan I oligosaccharide]
102211	unsaturated rhamnogalacturonyl hydrolase activity	F	Catalysis of the reaction: 2-O-(4-deoxy-beta-L-threo-hex-4-enopyranuronosyl)-alpha-L-rhamnopyranose(1-) + H2O <=> (4S,5S)-4,5-dihydroxy-2,6-dioxohexanoate + alpha-L-rhamnopyranose
102224	GDP-2,4-diacetamido-2,4,6-trideoxy-alpha-D-glucopyranose hydrolase/2-epimerase activity	F	Catalysis of the reaction: GDP-2,4-diacetamido-2,4,6-trideoxy-alpha-D-glucopyranose + H2O <=> 2,4-diacetamido-2,4,6-trideoxy-alpha-D-mannopyranose + GDP + H+
102225	4,4'-diaponeurosporene desaturase activity	F	Catalysis of the reaction: 4,4'-diaponeurosporene + FAD + H+ <=> 4,4'-diapolycopene + FADH2
102232	acrolein reductase activity	F	Catalysis of the reaction: acrolein + NADPH + H+ <=> propanal + NADP
102233	crotonaldehyde redutase activity	F	Catalysis of the reaction: (cis)-crotonaldehyde + NADPH + H+ <=> butanal + NADP.
102240	soyasapogenol B glucuronide galactosyltransferase activity	F	Catalysis of the reaction: UDP-D-galactose + soyasapogenol B 3-O-beta-glucuronate <=> H+ + UDP + soyasaponin III
102241	soyasaponin III rhamnosyltransferase activity	F	Catalysis of the reaction: UDP-L-rhamnose + soyasaponin III <=> H+ + UDP + soyasaponin I
102246	6-amino-6-deoxyfutalosine hydrolase activity	F	Catalysis of the reaction: aminodeoxyfutalosinate + H2O <=> dehypoxanthine futalosine + adenine.
102251	all-trans-beta-apo-10'-carotenal cleavage oxygenase activity	F	Catalysis of the reaction: 10'-apo-beta-carotenal + O2 <=> 13-apo-beta-carotenone + 4-methylocta-2,4,6-trienedial
102253	neoagarobiose 1,3-alpha-3,6-anhydro-L-galactosidase activity	F	Catalysis of the reaction: neoagarobiose + H2O <=> 3,6-anhydro-alpha-L-galactopyranose + beta-D-galactoside.
102254	neoagarotetraose 1,3-alpha-3,6-anhydro-L-galactosidase activity	F	Catalysis of the reaction: neoagarotetraose + H2O <=> 3,6-anhydro-alpha-L-galactopyranose + agarotriose.
102255	neo-lambda-carrahexaose hydrolase activity	F	Catalysis of the reaction: neo-lambda-carrahexaose + H2O <=> neo-lambda-carratetraose + neo-lambda-carrabiose
102256	neoagarohexaose 1,3-alpha-3,6-anhydro-L-galactosidase activity	F	Catalysis of the reaction: neoagarohexaose + H2O <=> 3,6-anhydro-alpha-L-galactopyranose + agaropentaose.
102260	germacrene A alcohol dehydrogenase activity	F	Catalysis of the reaction: germacra-1(10),4,11(13)-trien-12-ol + 2 NADP + H2O <=> germacra-1(10),4,11(13)-trien-12-oate + 2 NADPH + 3 H+
102261	8-hydroxy-5-deazaflavin:NADPH oxidoreductase activity	F	Catalysis of the reaction: NADP + a reduced coenzyme F420 <=> NADPH + H+ + an oxidized coenzyme F420
102262	tRNA-dihydrouridine16 synthase activity	F	Catalysis of the reaction: a 5,6-dihydrouracil16 in tRNA + NAD(P) <=> H+ + a uracil16 in tRNA + NAD(P)H
102263	tRNA-dihydrouridine17 synthase activity	F	Catalysis of the reaction: a 5,6-dihydrouracil17 in tRNA + NAD(P) <=> H+ + a uracil17 in tRNA + NAD(P)H
102264	tRNA-dihydrouridine20 synthase activity	F	Catalysis of the reaction: a 5,6-dihydrouracil20 in tRNA + NAD(P) <=> H+ + a uracil20 in tRNA + NAD(P)H
102265	tRNA-dihydrouridine47 synthase activity	F	Catalysis of the reaction: a 5,6-dihydrouracil47 in tRNA + NAD(P) <=> H+ + a uracil47 in tRNA + NAD(P)H
102266	tRNA-dihydrouridine20a synthase activity	F	Catalysis of the reaction: a 5,6-dihydrouracil20a in tRNA + NAD(P) <=> H+ + a uracil20a in tRNA + NAD(P)H
102267	tRNA-dihydrouridine20b synthase activity	F	Catalysis of the reaction: a 5,6-dihydrouracil20b in tRNA + NAD(P) <=> H+ + a uracil20b in tRNA + NAD(P)H
102279	lecithin:11-cis retinol acyltransferase activity	F	Catalysis of the reaction: an 11-cis retinol-[cellular-retinol-binding-protein] + a phosphatidylcholine <=> a cellular-retinol-binding protein + an 11-cis-retinyl ester + a 1-lysophosphatidylcholine
102281	formylaminopyrimidine deformylase activity	F	Catalysis of the reaction: formylaminopyrimidine + H2O <=> 4-amino-5-ammoniomethyl-2-methylpyrimidine + formate
102282	3-ketodihydrosphinganine (C18) reductase activity	F	Catalysis of the reaction: NAD(1-) + a sphinganine <=> 3-dehydrosphinganinium(1+) + NADH + H+
102283	3-ketodihydrosphinganine (C20) reductase activity	F	Catalysis of the reaction: C20 sphinganine(1+) + NADP <=> C20 3-dehydrosphinganine(1+) + NADPH + H+
102284	L-threo-sphinganine reductase activity	F	Catalysis of the reaction: L-threo-sphinganine + NADP <=> H+ + NADPH + 3-dehydrosphinganinium(1+)
102287	4-coumaroylhexanoylmethane synthase activity	F	Catalysis of the reaction: 4-coumaryl-CoA + 3-oxooctanoyl-CoA + H2O <=> 4-coumaroylhexanoylmethane + 2 coenzyme A + carbon dioxide.
102289	beta-amyrin 11-oxidase activity	F	Catalysis of the reaction: beta-amyrin + 2 O2 + 2 NADPH + 2 H+ <=> 11-oxo-beta-amyrin + 3 H2O + 2 NADP.
102290	beta-amyrin monooxygenase activity	F	Catalysis of the reaction: beta-amyrin + O2 + NADPH + H+ <=> 11alpha-hydroxy-beta-amyrin + H2O + NADP
102292	30-hydroxy-beta-amyrin 11-hydroxylase activity	F	Catalysis of the reaction: 30-hydroxy-beta-amyrin + O2 + NADPH + H+ <=> 11alpha,30-dihydroxy-beta-amyrin + H2O + NADP.
102293	pheophytinase b activity	F	Catalysis of the reaction: pheophytin b + H2O <=> H+ + pheophorbide b + phytol.
102295	4-methylumbelliferyl glucoside 6'-O-malonyltransferase activity	F	Catalysis of the reaction: 4-methylumbelliferyl glucoside + malonyl-CoA <=> 4-methylumbelliferone 6'-O-malonylglucoside + coenzyme A.
102296	4,5-9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase activity	F	Catalysis of the reaction: (1E,2Z)-3-hydroxy-5,9,17-trioxo-4,5:9,10-disecoandrosta-1(10),2-dien-4-oate + H2O <=> 9,17-dioxo-1,2,3,4,10,19-hexanorandrostan-5-oate + (2Z,4Z)-2-hydroxyhexa-2,4-dienoate + H+.
102299	linolenate 9R-lipoxygenase activity	F	Catalysis of the reaction: alpha-linolenate + O2 <=> (9R,10E,12Z,15Z)-9-hydroperoxyoctadeca-10,12,15-trienoate
102302	mycinamicin VI 2''-O-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + mycinamicin VI <=> S-adenosyl-L-homocysteine + mycinamicin III(1+) + H+.
102304	sesquithujene synthase activity	F	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate(3-) <=> 7-epi-sesquithujene + diphosphoric acid.
102307	erythromycin C 3''-o-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + erythromycin C <=> S-adenosyl-L-homocysteine + erythromycin A + H+
102308	erythromycin D 3''-o-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + erythromycin D <=> S-adenosyl-L-homocysteine + erythromycin B + H+
102312	4-coumaroyl 2'-hydroxylase activity	F	Catalysis of the reaction: 4-coumaryl-CoA + 2-oxoglutarate + O2 <=> 2,4-dihydroxycinnamoyl-CoA + succinate + carbon dioxide
102313	1,8-cineole synthase activity	F	Catalysis of the reaction: geranyl diphosphate(3-) + H2O <=> 1,8-cineole + diphosphoric acid
102315	lipoatemdashprotein ligase activity	F	Catalysis of the reaction: lipoyl-AMP + [glycine cleavage system lipoyl-carrier protein]-L-lysine <=> AMP + 2 H+ + a [glycine-cleavage complex H protein] N6-lipoyl-L-lysine
102318	2-deoxystreptamine glucosyltransferase activity	F	Catalysis of the reaction: 2-deoxystreptamine + UDP-alpha-D-glucose <=> 2'-deamino-2'-hydroxyparomamine + UDP(3-) + H+
102319	2-deoxystreptamine N-acetyl-D-glucosaminyltransferase activity	F	Catalysis of the reaction: 2-deoxystreptamine(2+) + UDP-N-acetyl-alpha-D-glucosamine <=> H+ + 2'-N-acetylparomamine(2+) + UDP(3-)
102320	1,8-cineole 2-exo-monooxygenase activity	F	Catalysis of the reaction: 1,8-cineole + NADPH + H+ + O2 <=> 2-exo-hydroxy-1,8-cineole + NADP + H2O
102321	2,2'-hydroxybiphenyl monooxygenase activity	F	Catalysis of the reaction: biphenyl-2,2'-diol + O2 + NADH + H+ <=> biphenyl-2,2',3-triol + H2O + NAD
102329	hentriaconta-3,6,9,12,19,22,25,28-octaene-16-one-15-oyl-CoA reductase activity	F	Catalysis of the reaction: 16-hydroxy-hentriaconta-3,6,9,12,19,22,25,28-octaene-15-oyl-CoA + NADP <=> hentriaconta-3,6,9,12,19,22,25,28-octaene-16-one-15-oyl-CoA + NADPH + H+.
102334	N,N'-diacetylbacilliosaminyl-1-phosphate transferase activity	F	Catalysis of the reaction: ditrans,polycis-undecaprenyl phosphate + UDP-N,N'-diacetylbacillosamine <=> N,N'-diacetyl-alpha-D-bacillosaminyl-diphospho-tri-trans,hepta-cis-undecaprenol + UMP.
102335	N,N'-diacetylbacillosaminyl-diphospho-undecaprenol alpha-1,3-N-acetylgalactosaminyltransferase activity	F	Catalysis of the reaction: N,N'-diacetyl-alpha-D-bacillosaminyl-diphospho-tri-trans,hepta-cis-undecaprenol + UDP-N-acetyl-D-galactosamine <=> N-acetyl-D-galactosaminyl-alpha-(1->3)-N,N'-diacetyl-alpha-D-bacillosaminyl-diphospho-tri-trans,hepta-cis-undecaprenol + UDP + H+.
102336	3-oxo-arachidoyl-CoA synthase activity	F	Catalysis of the reaction: stearoyl-CoA(4-) + malonyl-CoA(5-) + H+ <=> 3-oxoicosanoyl-CoA. + carbon dioxide + coenzyme A.
102337	3-oxo-cerotoyl-CoA synthase activity	F	Catalysis of the reaction: tetracosanoyl-CoA(4-) + malonyl-CoA(5-) + H+ <=> 3-oxohexacosanoyl-CoA + carbon dioxide + coenzyme A.
102338	3-oxo-lignoceronyl-CoA synthase activity	F	Catalysis of the reaction: behenoyl-CoA(4-) + malonyl-CoA(5-) + H+ <=> 3-oxotetracosanoyl-CoA. + carbon dioxide + coenzyme A.
102339	3-oxo-arachidoyl-CoA reductase activity	F	Catalysis of the reaction: (R)-3-hydroxyicosanoyl-CoA(4-) + NADP(3-) <=> 3-oxoicosanoyl-CoA + NADPH + H+.
102340	3-oxo-behenoyl-CoA reductase activity	F	Catalysis of the reaction: (R)-3-hydroxybehenoyl-CoA(4-) + NADP(3-) <=> 3-oxodocosanoyl-CoA + NADPH + H+.
102341	3-oxo-lignoceroyl-CoA reductase activity	F	Catalysis of the reaction: (R)-3-hydroxylignoceroyl-CoA + NADP <=> 3-oxotetracosanoyl-CoA + NADPH + H+.
102342	3-oxo-cerotoyl-CoA reductase activity	F	Catalysis of the reaction: (R)-3-hydroxycerotoyl-CoA + NADP <=> 3-oxohexacosanoyl-CoA + NADPH + H+
102344	3-hydroxy-behenoyl-CoA dehydratase activity	F	Catalysis of the reaction: (R)-3-hydroxybehenoyl-CoA <=> trans-2-docosenoyl-CoA + H2O.
102345	3-hydroxy-lignoceroyl-CoA dehydratase activity	F	Catalysis of the reaction: (R)-3-hydroxylignoceroyl-CoA(4-) <=> trans-2-tetracosenoyl-CoA + H2O.
102348	trans-docosan-2-enoyl-CoA reductase activity	F	Catalysis of the reaction: behenoyl-CoA + NADP <=> trans-2-docosenoyl-CoA + NADPH + H+
102349	trans-lignocero-2-enoyl-CoA reductase activity	F	Catalysis of the reaction: tetracosanoyl-CoA + NADP <=> trans-2-tetracosenoyl-CoA + NADPH + H+
102350	trans-cerot-2-enoyl-CoA reductase activity	F	Catalysis of the reaction: hexacosanoyl-CoA(4-) + NADP(3-) <=> trans-2-hexacosenoyl-CoA + NADPH + H+
102353	multiradiene synthase activity	F	Catalysis of the reaction: 5alpha,9alpha,10beta-labda-8(20),13-dien-15-yl diphosphate <=> miltiradiene + diphosphoric acid
102355	2-oxo-3-(5-oxofuran-2-ylidene)propanoate lactonase activity	F	Catalysis of the reaction: 2-oxo-3-(5-oxofuran-2-ylidene)propanoate + H2O <=> 3-maleylpyruvate + H+
102356	isoitalicene synthase activity	F	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate(3-) <=> diphosphoric acid + (+)-isoitalicene
102357	mithramycin dehydrogenase activity	F	Catalysis of the reaction: mithramycin + NADP <=> mithramycin DK + NADPH + H+
102358	daphnetin-8-O-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + 7,8-dihydroxycoumarin <=> S-adenosyl-L-homocysteine + 7-hydroxy-8-methoxycoumarin + H+
102359	daphnetin 4-O-beta-glucosyltransferase activity	F	Catalysis of the reaction: UDP-alpha-D-glucose + 7,8-dihydroxycoumarin <=> UDP + 4-O- beta -D-glucosyl-daphnetin + H+
102360	daphnetin 3-O-glucosyltransferase activity	F	Catalysis of the reaction: UDP-alpha-D-glucose(2-) + 7,8-dihydroxycoumarin <=> UDP(3-) + 3-O-beta-D-glucosyl-daphnetin + H+
102361	esculetin 4-O-beta-glucosyltransferase activity	F	Catalysis of the reaction: esculetin + UDP-alpha-D-glucose <=> 4-O-beta-D-glucosyl-esculetin + UDP + H+
102362	esculetin 3-O-glucosyltransferase activity	F	Catalysis of the reaction: esculetin + UDP-alpha-D-glucose <=> 3-O-beta-D-glucosyl-esculetin + UDP + H+
102363	isoscopoletin-O-methyltransferase activity	F	Catalysis of the reaction: isoscopoletin + S-adenosyl-L-methionine <=> scoparone + S-adenosyl-L-homocysteine + H+
102368	beta-amyrin 30-monooxygenase activity	F	Catalysis of the reaction: beta-amyrin + NADPH + H+ + O2 <=> 30-hydroxy-beta-amyrin + NADP + H2O
102369	11alpha-30-dihydroxy beta-amyrin dehydrogenase activity	F	Catalysis of the reaction: 11alpha,30-dihydroxy-beta-amyrin + NADPH + O2 + H+ <=> 30-hydroxy-11-oxo-beta-amyrin + NADP + 2 H2O
102370	lupeol 28-monooxygenase activity	F	Catalysis of the reaction: lupeol + NADPH(4-) + O2 + H+ <=> betulin + NADP(3-) + H2O
102371	betulin dehydrogenase activity	F	Catalysis of the reaction: betulin + NADPH(4-) + H+ + O2 <=> betulinic aldehyde + NADP(3-) + 2 H2O
102372	alpha-amyrin 28-monooxygenase activity	F	Catalysis of the reaction: alpha-amyrin + NADPH(4-) + O2 + H+ <=> uvaol + NADP(3-) + H2O
102373	uvaol dehydrogenase activity	F	Catalysis of the reaction: uvaol + NADPH + O2 + H+ <=> ursolic aldehyde + NADP + 2 H2O
102374	ursolic aldehyde 28-monooxygenase activity	F	Catalysis of the reaction: ursolic aldehyde + NADPH + O2 + H+ <=> ursolic acid + NADP + H2O
102375	11-oxo-beta-amyrin 30-oxidase activity	F	Catalysis of the reaction: 11-oxo-beta-amyrin + 3 NADPH + 3 O2 + 2 H+ <=> glycyrrhetinic acid + 3 NADP + 4 H2O
102376	lupeol 28-oxidase activity	F	Catalysis of the reaction: lupeol + 3 NADPH + 3 O2 + 3 H+ <=> betulinic acid + 3 NADP + 4 H2O
102382	rebaudioside B glucosyltransferase activity	F	Catalysis of the reaction: rebaudioside B + UDP-alpha-D-glucose <=> rebaudioside A + UDP + H+
102383	steviol glucosyltransferase activity	F	Catalysis of the reaction: steviol + UDP-alpha-D-glucose <=> 19-O-beta-glucopyranosyl-steviol + UDP + H+
102384	19-O-beta-glucopyranosyl-steviol glucosyltransferase activity	F	Catalysis of the reaction: 19-O-beta-glucopyranosyl-steviol + UDP-alpha-D-glucose <=> rubusoside + UDP + H+
102385	patchoulol synthase activity	F	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate(3-) <=> seychellene + diphosphoric acid
102388	UDP-N,N'-diacetylbacillosamine 2-epimerase activity	F	Catalysis of the reaction: UDP-N,N'-diacetylbacillosamine + H2O <=> 2,4-diacetamido-2,4,6-trideoxy-alpha-D-mannopyranose + UDP + H+
102390	mycophenolic acid acyl-glucuronide esterase activity	F	Catalysis of the reaction: mycophenolic acid O-acyl-glucuronide(1-) + H2O <=> mycophenolate + H+ + D-glucopyranuronate
102391	decanoate--CoA ligase activity	F	Catalysis of the reaction: decanoate + ATP(4-) + coenzyme A(4-) <=> decanoyl-CoA(4-) + AMP(2-) + diphosphoric acid
102392	decanoate-[HmqF protein] ligase activity	F	Catalysis of the reaction: decanoate + ATP(4-) + an HmqF protein <=> AMP(2-) + diphosphoric acid + a decanoyl-HmqF protein
102393	decanoyl-[acp] 2-dehydrogenase activity	F	Catalysis of the reaction: FAD + H+ + a decanoyl-HmqF protein <=> FADH2(2-) + a 2,3-dehydro-decanoyl-HmqF
102394	4-hydroxy-L-isoleucine dehydrogenase activity	F	Catalysis of the reaction: (2S,3R,4S)-4-hydroxy-L-isoleucine + NAD <=> (2S,3R)-2-amino-3-methyl-4-ketopentanoate + NADH + H+
102398	dTDP-3-amino-4-oxo-2,3,6-trideoxy-alpha-D-glucose N-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + dTDP-3-amino-4-dehydro-2,3,6-trideoxy-alpha-D-glucose <=> S-adenosyl-L-homocysteine + dTDP-3-N-methylamino-4-oxo-2,3,6-trideoxy-alpha-D-glucose + H+
102399	dTDP-3-N-methylamino-4-oxo-2,3,6-trideoxy-alpha-D-glucose N-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + dTDP-3-N-methylamino-4-oxo-2,3,6-trideoxy-alpha-D-glucose <=> S-adenosyl-L-homocysteine + dTDP-3-N,N-dimethylamino-4-oxo-2,3,6-trideoxy-alpha-D-glucose + H+
102400	dTDP-3-amino-4-oxo-2,3,6-trideoxy-alpha-D-glucose N,N-dimethyltransferase activity	F	Catalysis of the reaction: 2 S-adenosyl-L-methionine + dTDP-3-amino-4-dehydro-2,3,6-trideoxy-alpha-D-glucose <=> 2 S-adenosyl-L-homocysteine + dTDP-3-N,N-dimethylamino-4-oxo-2,3,6-trideoxy-alpha-D-glucose + 2 H+
102404	linalyl 6-O-alpha-L-arabinopyranosyl-beta-D-glucopyranoside glucosidase (Yabukita) activity	F	Catalysis of the reaction: linalyl 6-O-alpha-L-arabinopyranosyl- beta-D-glucopyranoside + H2O <=> vicianose + linalool
102405	(+)-taxifolin 5'-hydroxylase activity	F	Catalysis of the reaction: (+)-taxifolin(1-) + O2 + NADPH(4-) + H+ <=> (+)-dihydromyricetin + NADP(3-) + H2O
102406	omega-hydroxypalmitate O-sinapoyl transferase activity	F	Catalysis of the reaction: sinapoyl-CoA + 16-hydroxypalmitate <=> coenzyme A + 16-sinapoyloxypalmitate
102410	quercetin-4',3-O-glucosyltransferase activity	F	Catalysis of the reaction: quercetin 4'-O-glucoside + UDP-alpha-D-glucose(2-) <=> quercetin 3,4'-O-diglucoside + UDP(3-)
102411	quercetin-3,4'-O-glucosyltransferase activity	F	Catalysis of the reaction: quercetin-3-glucoside + UDP-alpha-D-glucose(2-) <=> quercetin 3,4'-O-diglucoside + UDP(3-)
102412	valerena-4,7(11)-diene synthase activity	F	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate(3-) <=> valerena-4,7(11)-diene + diphosphoric acid
102413	6-O-methyl-deacetylisoipecoside beta-glucosidase activity	F	Catalysis of the reaction: 6-O-methyl-N-deacetylisoipecoside + H2O <=> 6-O-methyl-N-deacetylisoipecoside aglycon + beta-D-glucose
102414	quercetin-3-O-glucoside 1,6-glucosyltransferase activity	F	Catalysis of the reaction: quercetin-3-glucoside + UDP-alpha-D-glucose(2-) <=> quercetin-3-gentiobioside + UDP
102415	quercetin gentiobioside 1,6-glucosyltransferase activity	F	Catalysis of the reaction: quercetin-3-gentiobioside + UDP-alpha-D-glucose <=> quercetin-3-gentiotrioside + UDP + H+
102416	quercetin gentiotrioside 1,6-glucosyltransferase activity	F	Catalysis of the reaction: quercetin-3-gentiotrioside + UDP-alpha-D-glucose <=> quercetin-3-gentiotetraside + UDP + H+
102417	apigenin-7-O-glucoside 1,6-glucosyltransferase activity	F	Catalysis of the reaction: apigenin 7-O-beta-D-glucoside + UDP-alpha-D-glucose <=> apigenin-7-O-gentiobioside + UDP + H+
102421	curcumin-4'-O-beta-D-gentiobioside 1,6-glucosyltransferase activity	F	Catalysis of the reaction: curcumin 4'-O-beta-D-gentiobioside + UDP-alpha-D-glucose <=> curcumin 4'-O-beta-D-gentiotrioside + UDP + H+
102422	curcumin-4'-O-beta-D-gentiotrioside 1,6-glucosyltransferase activity	F	Catalysis of the reaction: curcumin 4'-O-beta-D-gentiotrioside + UDP-alpha-D-glucose <=> curcumin 4'-O-beta-D-gentiotetraside + UDP + H+
102423	(+)-sesaminol 2-O-glucosyltransferase activity	F	Catalysis of the reaction: (+)-sesaminol + UDP-alpha-D-glucose <=> (+)-sesaminol 2-O-beta-D-glucoside + UDP + H+
102424	sesaminol-2-O-gentiobioside 1,6-glucosyltransferase activity	F	Catalysis of the reaction: (+)-sesaminol 2-O-beta-D-gentiobioside + UDP-alpha-D-glucose <=> (+)-sesaminol 2-O-beta-D-gentiotrioside + UDP + H+
102425	myricetin 3-O-glucosyltransferase activity	F	Catalysis of the reaction: myricetin + UDP-alpha-D-glucose <=> myricetin 3-O-beta-D-glucopyranoside + UDP
102427	allocryptopine 6-hydroxylase activity	F	Catalysis of the reaction: allocryptopine + NADPH + O2 + H+ <=> 6-hydroxy-allocryptopine + NADP + H2O
102428	kaempferol-3-O-glucoside 1,6-glucosyltransferase activity	F	Catalysis of the reaction: kaempferol 3-O-glucoside + UDP-alpha-D-glucose <=> kaempferol-3-gentiobioside + UDP
102429	genistein-3-O-glucoside 1,6-glucosyltransferase activity	F	Catalysis of the reaction: genistin + UDP-alpha-D-glucose <=> genistin 7-gentiobioside + UDP + H+
102432	quercetin 7-O-methyltransferase activity	F	Catalysis of the reaction: quercetin-7-olate + S-adenosyl-L-methionine <=> rhamnetin + S-adenosyl-L-homocysteine
102435	myricetin 7-O-methyltransferase activity	F	Catalysis of the reaction: myricetin(1-) + S-adenosyl-L-methionine <=> 7-O-methylmyricetin + S-adenosyl-L-homocysteine
102436	7-methylmyricetin 4'-O-methyltransferase activity	F	Catalysis of the reaction: 7-O-methylmyricetin + S-adenosyl-L-methionine <=> 7,4'-dimethylmyricetin + S-adenosyl-L-homocysteine + H+
102437	myricetin 3-O-methyltransferase activity	F	Catalysis of the reaction: myricetin(1-) + S-adenosyl-L-methionine <=> 3-O-methylmyricetin + S-adenosyl-L-homocysteine
102438	laricitrin 4'-O-methyltransferase activity	F	Catalysis of the reaction: laricitrin(1-) + S-adenosyl-L-methionine <=> H+ + 3',4'-dimethylmyricetin + S-adenosyl-L-homocysteine
102439	3',4',5'-trimethylmyricetin 7-O-methyltransferase activity	F	Catalysis of the reaction: 3',4',5'-trimethylmyricetin + S-adenosyl-L-methionine <=> 7,3',4',5'-tetramethylmyricetin + S-adenosyl-L-homocysteine + H+
102440	3',4',5'-trimethylmyricetin 3-O-methyltransferase activity	F	Catalysis of the reaction: 3',4',5'-trimethylmyricetin + S-adenosyl-L-methionine <=> 3,3',4',5'-tetramethylmyricetin + S-adenosyl-L-homocysteine + H+
102441	syringetin 7-O-methyltransferase activity	F	Catalysis of the reaction: syringetin(1-) + S-adenosyl-L-methionine <=> 7,3',5'-trimethylmyricetin + S-adenosyl-L-homocysteine
102442	syringetin 3-O-methyltransferase activity	F	Catalysis of the reaction: syringetin(1-) + S-adenosyl-L-methionine <=> 3,3',5'-trimethylmyricetin + S-adenosyl-L-homocysteine
102443	L-2-hydroxycarboxylate dehydrogenase (NAD+) activity	F	Catalysis of the reaction: NAD(1-) + a (2S)-2-hydroxycarboxylate <=> NADH(2-) + H+ + a 2-oxo carboxylate
102444	isorhamnetin 3-O-methyltransferase activity	F	Catalysis of the reaction: isorhamnetin + S-adenosyl-L-methionine <=> 3,3'-dimethylquercetin + S-adenosyl-L-homocysteine
102445	3-methylquercetin 3'-O-methyltransferase activity	F	Catalysis of the reaction: 3',4',5-trihydroxy-3-methoxyflavon-7-olate + S-adenosyl-L-methionine <=> 3,3'-dimethylquercetin + S-adenosyl-L-homocysteine
102446	rhamnetin 3-O-methyltransferase activity	F	Catalysis of the reaction: rhamnetin + S-adenosyl-L-methionine <=> 3',4',5-trihydroxy-3,7-dimethoxyflavone + S-adenosyl-L-homocysteine + H+
102447	rhamnetin 3'-O-methyltransferase activity	F	Catalysis of the reaction: rhamnetin + S-adenosyl-L-methionine <=> 7,3'-dimethylquercetin + S-adenosyl-L-homocysteine + H+
102448	rhamnetin 4'-O-methyltransferase activity	F	Catalysis of the reaction: rhamnetin + S-adenosyl-L-methionine <=> ombuin + S-adenosyl-L-homocysteine + H+
102449	kaempferol 3-O-methyltransferase activity	F	Catalysis of the reaction: kaempferol oxoanion + S-adenosyl-L-methionine <=> 3-O-methylkaempferol + S-adenosyl-L-homocysteine
102450	kaempferide 7-O-methyltransferase activity	F	Catalysis of the reaction: kaempferide + S-adenosyl-L-methionine <=> 7,4'-dimethylkaempferol + S-adenosyl-L-homocysteine
102451	kaempferide 3-O-methyltransferase activity	F	Catalysis of the reaction: kaempferide + S-adenosyl-L-methionine <=> 3,4'-dimethylkaempferol + S-adenosyl-L-homocysteine
102452	bisdemethoxycurcumin synthase activity	F	Catalysis of the reaction: 2 4-coumaryl-CoA + malonyl-CoA + H2O + H+ <=> 3 coenzyme A + bisdemethoxycurcumin + 2 carbon dioxide
102464	zeaxanthin 2-beta-hydroxylase activity	F	Catalysis of the reaction: zeaxanthin + O2 + NADH + H+ <=> caloxanthin + H2O + NAD
102465	zeaxanthin 2,2'-beta-hydroxylase activity	F	Catalysis of the reaction: zeaxanthin + 2 NADH + 2 H+ + 2 O2 <=> nostoxanthin + 2 NAD + 2 H2O
102467	scutellarein 7-O-glucuronosyltransferase activity	F	Catalysis of the reaction: UDP-alpha-D-glucuronate + scutellarein <=> UDP( + scutellarin + H+
102468	wogonin 7-O-glucuronosyltransferase activity	F	Catalysis of the reaction: UDP-alpha-D-glucuronate + wogonin <=> UDP + wogonin 7-O-beta-D-glucuronate + H+
102469	naringenin 2-hydroxylase activity	F	Catalysis of the reaction: (S)-naringenin + NADPH + O2 <=> 2-hydroxynaringenin + NADP + H2O
102470	6C-naringenin dibenzoylmethane tautomer glucosyltransferase activity	F	Catalysis of the reaction: 2,4,4',6-tetrahydroxydibenzoylmethane + UDP-alpha-D-glucose <=> 6C-glucosyl-2-hydroxynaringenin + UDP + H+
102471	2-hydroxynaringenin-6C-glucoside dehydratase activity	F	Catalysis of the reaction: 6C-glucosyl-2-hydroxynaringenin <=> isovitexin-7-olate + H2O
102472	eriodictyol 2-hydroxylase activity	F	Catalysis of the reaction: eriodictyol + NADPH + O2 + 2 H+ <=> 2-hydroxyeriodictyol + NADP + H2O
102473	eriodictyol dibenzoylmethane tautomer 8C-glucosyltransferase activity	F	Catalysis of the reaction: eriodictyol dibenzoylmethane tautomer + UDP-alpha-D-glucose <=> 8C-beta-D-glucosyl-2-hydroxyeriodictyol + UDP(3-) + H+
102474	eriodictyol dibenzoylmethane tautomer 6C-glucosyltransferase activity	F	Catalysis of the reaction: eriodictyol dibenzoylmethane tautomer + UDP-alpha-D-glucose <=> 6C-beta-D-glucosyl-2-hydroxyeriodictyol + UDP + H+
102475	2-hydroxyeriodictyol 6C-glucoside dehydratase activity	F	Catalysis of the reaction: 6C-beta-D-glucosyl-2-hydroxyeriodictyol <=> isoorientin + H2O
102476	pinocembrin 2-hydroxylase activity	F	Catalysis of the reaction: pinocembrin + NADPH + O2 + H+ <=> 2,5,7-trihydroxyflavanone + NADP + H2O
102479	quercetin 3-O-beta:-D-galactosyltransferase activity	F	Catalysis of the reaction: quercetin-7-olate + UDP-D-galactose <=> quercetin 3-O-beta-D-galactopyranoside + UDP(3-) + H+
102480	5-fluorocytosine deaminase activity	F	Catalysis of the reaction: H+ + flucytosine + H2O <=> 5-fluorouracil + ammonium
102481	3D-(3,5/4)-trihydroxycyclohexane-1,2-dione hydrolase activity	F	Catalysis of the reaction: 3D-3,5/4-trihydroxycyclohexane-1,2-dione + H2O <=> 5-deoxy-D-glucuronate + H+
102483	scopolin beta-glucosidase activity	F	Catalysis of the reaction: H2O + scopolin <=> beta-D-glucose + scopoletin
102484	esculetin glucosyltransferase activity	F	Catalysis of the reaction: esculetin + UDP-alpha-D-glucose(2-) <=> esculin + UDP(3-) + H+
102490	8-oxo-dGTP phosphohydrolase activity	F	Catalysis of the reaction: 8-oxo-dGTP + 2 H2O <=> 8-oxo-dGMP + 2 hydrogenphosphate + 2 H+
102493	wogonin 7-O-glucosyltransferase activity	F	Catalysis of the reaction: wogonin + UDP-alpha-D-glucose <=> wogonin 7-O-beta-D-glucoside + UDP + H+
102497	scyllo-inositol dehydrogenase (NADP+) activity	F	Catalysis of the reaction: scyllo-inositol + NADP <=> 2,4,6/3,5-pentahydroxycyclohexanone + NADPH + H+
102505	apigeninidin 5-O-glucosyltransferase activity	F	Catalysis of the reaction: apigeninidin + UDP-alpha-D-glucose <=> apigeninidin 5-O-glucoside + UDP + H+
102508	cyanidin 3,7-diglucoside glucosidase activity	F	Catalysis of the reaction: cyanidin 3,7-di-O-beta-D-glucoside betaine + H2O <=> cyanidin 3-O-beta-D-glucoside betaine + beta-D-glucose
102509	cyanidin 3,5-diglucoside glucosidase activity	F	Catalysis of the reaction: cyanin betaine + H2O <=> cyanidin 3-O-beta-D-glucoside betaine + beta-D-glucose
102510	pelargonidin 3-O-glucoside 5-O-glucosyltransferase (acyl-glucose dependent) activity	F	Catalysis of the reaction: pelargonidin 3-O-beta-D-glucoside + 1-O-vanilloyl-beta-D-glucose <=> anthocyanidin 3,5-di-O-beta-D-glucoside + vanillate + H+
102511	pelargonidin 3-O-glucoside 7-O-glucosyltransferase (acyl-glucose dependent) activity	F	Catalysis of the reaction: pelargonidin 3-O-beta-D-glucoside + 1-O-vanilloyl-beta-D-glucose <=> pelargonidin 3,7-di-O-beta-D-glucoside + vanillate + H+
102512	delphinidin 3-O-glucoside 5-O-glucosyltransferase (acyl-glucose dependent) activity	F	Catalysis of the reaction: delphinidin 3-O-beta-D-glucoside + 1-O-vanilloyl-beta-D-glucose <=> delphinidin 3-O-beta-D-glucoside-5-O-beta-D-glucoside betaine + vanillate + H+
102522	tRNA 4-demethylwyosine alpha-amino-alpha-carboxypropyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + 4-demethylwyosine37 in tRNAPhe <=> 5'-S-methyl-5'-thioadenosine + H+ + 7-[(3S)-3-amino-3-carboxypropyl]-4-demethylwyosine37 in tRNAPhe
102527	8-demethylnovobiocate synthase activity	F	Catalysis of the reaction: 3-amino-4,7-dihydroxycoumarin + 3-dimethylallyl-4-hydroxybenzoate + ATP(4-) <=> H+ + 8-desmethylnovobiocic acid(1-) + AMP(2-) + diphosphoric acid
102529	apigenin 7-O-methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + apigenin-7-olate <=> S-adenosyl-L-homocysteine + genkwanin
102530	aclacinomycin T methylesterase activity	F	Catalysis of the reaction: aclacinomycin T(1+) + H2O <=> 15-demethylaclacinomycin T + methanol + H+
102532	genkwanin 6-hydroxylase activity	F	Catalysis of the reaction: genkwanin + O2 + NADPH + H+ <=> scutellarein 7-methyl ether + H2O + NADP
102533	genkwanin 4'-O-methyltransferase activity	F	Catalysis of the reaction: genkwanin + S-adenosyl-L-methionine <=> H+ + apigenin-7,4'-dimethyl ether + S-adenosyl-L-homocysteine
102534	apigenin-7,4'-dimethyl ether 6-hydroxylase activity	F	Catalysis of the reaction: apigenin-7,4'-dimethyl ether + O2 + NADPH + H+ <=> ladanein + H2O + NADP
102535	ladanein 6-O-methyltransferase activity	F	Catalysis of the reaction: ladanein + S-adenosyl-L-methionine <=> H+ + salvigenin + S-adenosyl-L-homocysteine
102536	sakuranetin 6-hydroxylase activity	F	Catalysis of the reaction: sakuranetin + O2 + NADPH + H+ <=> carthamidin-7-methyl ether + H2O + NADP
102542	aclacinomycin A methylesterase activity	F	Catalysis of the reaction: aclacinomycin A + H2O <=> 15-demethoxy-aclacinomycin A + methanol + H+
102543	epsilon-rhodomycinone methylesterase activity	F	Catalysis of the reaction: epsilon-rhodomycinone + H2O <=> 15-demethoxy-epsilon-rhodomycinone + methanol + H+
102546	mannosylglycerate hydrolase activity	F	Catalysis of the reaction: H2O + 2-(alpha-D-mannosyl)-D-glycerate <=> alpha-D-mannose + D-glycerate
102547	glucosylglycerate hydrolase activity	F	Catalysis of the reaction: H2O + 2-O-(alpha-D-glucopyranosyl)-D-glycerate <=> alpha-D-glucose + D-glycerate
102549	1-18:1-2-16:0-monogalactosyldiacylglycerol lipase activity	F	Catalysis of the reaction: 1-18:1-2-16:0-monogalactosyldiacylglycerol + H2O <=> sn-1-lyso-2-16:0-monogalactosyldiacylglycerol + oleate + H+
102550	2-methyl-6-geranylgeranyl-1,4-benzoquinol methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + 2-methyl-6-geranylgeranyl-1,4-benzoquinol <=> S-adenosyl-L-homocysteine + 2,3-dimethyl-6-geranylgeranyl-1,4-benzoquinol + H+
102551	homogentisate geranylgeranyl transferase activity	F	Catalysis of the reaction: 2-trans,6-trans,10-trans-geranylgeranyl diphosphate + homogentisate + H+ <=> diphosphoric acid + 2-methyl-6-geranylgeranyl-1,4-benzoquinol + carbon dioxide
102556	dammarenediol 12-hydroxylase activity	F	Catalysis of the reaction: dammarenediol-II + NADPH + H+ + O2 <=> (20S)-protopanaxadiol + NADP + H2O
102557	protopanaxadiol 6-hydroxylase activity	F	Catalysis of the reaction: (20S)-protopanaxadiol + O2 + NADPH(4-) + H+ <=> protopanaxatriol + NADP + H2O
102563	aurachin C monooxygenase activity	F	Catalysis of the reaction: aurachin C + O2 + H+ + NAD(P)H <=> aurachin C epoxide + H2O + NAD(P)
102564	aurachin C epoxide hydrolase/isomerase activity	F	Catalysis of the reaction: aurachin C epoxide + H+ + NAD(P)H <=> aurachin B + H2O + NAD(P)
102569	FR-33289 synthase activity	F	Catalysis of the reaction: FR-900098 + 2-oxoglutarate(2-) + O2 <=> FR-33289 + succinate(2-) + carbon dioxide
102573	aminodeoxyfutalosine synthase activity	F	Catalysis of the reaction: 3-[(1-carboxylatovinyl)oxy]benzoate(2-) + S-adenosyl-L-methionine + H2O <=> aminodeoxyfutalosinate + L-methionine + hydrogencarbonate + H+
102580	cyanidin 3-O-glucoside 2-O''-xylosyltransferase activity	F	Catalysis of the reaction: cyanidin 3-O-beta-D-glucoside betaine + UDP-alpha-D-xylose <=> cyanidin 3-O-beta-D-sambubioside + UDP
102581	cyanidin 3-O-glucoside-p-coumaroyltransferase activity	F	Catalysis of the reaction: cyanidin 3-O-beta-D-glucoside betaine + 4-coumaryl-CoA + H+ <=> cyanidin 3-O-(6-O-(E)-4-coumaroyl-beta-D-glucoside) + coenzyme A
102582	cyanidin 3-O-p-coumaroylglucoside 2-O''-xylosyltransferase activity	F	Catalysis of the reaction: cyanidin 3-O-(6-O-(E)-4-coumaroyl-beta-D-glucoside) + UDP-alpha-D-xylose <=> cyanidin 3-O-[2''-O-xylosyl) 6''-O-(p-coumaroyl) glucoside + UDP + H+.
102583	cyanidin 3-O-glucoside-(2''-O-xyloside) 6''-O-acyltransferase activity	F	Catalysis of the reaction: cyanidin 3-O-beta-D-sambubioside + 4-coumaryl-CoA <=> cyanidin 3-O-[2''-O-xylosyl) 6''-O-(p-coumaroyl) glucoside + coenzyme A.
102584	cyanidin 3-O-[2''-O-(xylosyl)-6''-O-(p-coumaroyl) glucoside] 5-O-glucosyltransferase activity 5-O-glucosyltransferase activity	F	Catalysis of the reaction: cyanidin 3-O-[2''-O-xylosyl) 6''-O-(p-coumaroyl) glucoside + UDP-alpha-D-glucose <=> cyanidin 3-O-[2''-O-(xylosyl)-6''-O-(p-coumaroyl) glucoside] 5-O-glucoside + UDP + H+
102585	cyanidin 3-O-[2''-O-(xylosyl)-6''-O-(p-coumaroyl) glucoside] 5-O-glucoside malonyltransferase activity	F	Catalysis of the reaction: cyanidin 3-O-[2''-O-(xylosyl)-6''-O-(p-coumaroyl) glucoside] 5-O-glucoside + malonyl-CoA + H+ <=> cyanidin 3-O-[2''-O-(xylosyl)-6''-O-(p-coumaroyl) glucoside] 5-O-malonylglucoside + coenzyme A.
102586	cyanidin 3-O-[2''-O-(2''-O-(sinapoyl) xylosyl) 6''-O-(p-coumaroyl) glucoside] 5-O-[6''-O-(malonyl) glucoside] sinapoyltransferase activity	F	Catalysis of the reaction: cyanidin 3-O-[2''-O-(xylosyl)-6''-O-(p-coumaroyl) glucoside] 5-O-malonylglucoside + 1-O-sinapoyl-beta-D-glucose <=> cyanidin 3-O-[2''-O-(2''-O-(sinapoyl) xylosyl) 6'-O-(p-coumaroyl) glucoside] 5-O-[6''-O-(malonyl) glucoside + beta-D-glucose.
102587	cyanidin 3-O-[2''-O-(2''-O-(sinapoyl) xylosyl) 6''-O-(p-O-(glucosyl)-p-coumaroyl) glucoside] 5-O-[6''-O-(malonyl) glucoside] sinapoylglucose glucosyltransferase activity	F	Catalysis of the reaction: cyanidin 3-O-[2''-O-(2'''-O-(sinapoyl) xylosyl) 6''-O-(p-coumaroyl) glucoside] 5-O-[6''-O-(malonyl) glucoside + 1-O-sinapoyl-beta-D-glucose <=> cyanidin 3-O-[6-O-(4-O-beta-D-glucosyl-p-coumaroyl)-2-O-(2-O-sinapoyl-beta-D-xylosyl)-beta-D-glucosyl]-5-O-(6-O-malonyl-beta-D-glucoside) + trans-sinapate + H+.
102588	cyanidin 3-O-glucoside 6''-O-malonyltransferase activity	F	Catalysis of the reaction: cyanidin 3-O-beta-D-glucoside betaine + malonyl-CoA <=> cyanidin 3-O-(6-O-malonyl-beta-D-glucoside) + coenzyme A.
102589	cyanidin 3-O-glucoside 3'',6''-O-dimalonyltransferase activity	F	Catalysis of the reaction: cyanidin 3-O-(6-O-malonyl-beta-D-glucoside) + malonyl-CoA(5-) <=> cyanidin 3-O-(3''', 6''-O-dimalonyl-beta-glucopyranoside) + coenzyme A
102590	delphinidin 3-O-rutinoside 7-O-glucosyltransferase (acyl-glucose dependent) activity	F	Catalysis of the reaction: delphinidin 3-O-rutinoside + 1-O-4-hydroxybenzoyl-beta-D-glucose <=> delphinidin 3-O-rutinoside-7-O-glucoside + 4-hydroxybenzoic acid + H+
102591	delphinidin 7-O-glucoside acyltransferase (acyl-glucose dependent) activity	F	Catalysis of the reaction: delphinidin 3-O-rutinoside-7-O-glucoside + 1-O-4-hydroxybenzoyl-beta-D-glucose <=> delphinidin 3-O-rutinoside-7-O-(6-O-(p-hydroxybenzoyl)-glucoside) + beta-D-glucose
102592	delphinidin 7-O-(6-O-(4-O-(glucosyl)-oxybenzoyl)-glucoside) acyltransferase (acyl-glucose dependent activity	F	Catalysis of the reaction: delphinidin 3-O-rutinoside-7-O-(6-O-(4-O-(glucosyl)-oxybenzoyl)-glucoside) + 1-O-4-hydroxybenzoyl-beta-D-glucose <=> violdelphin + beta-D-glucose
102596	cytochrome P450 dependent ent-sandaracopimaradiene 3-hydroxylase activity	F	Catalysis of the reaction: ent-sandaracopimara-8(14),15-diene + NADPH + H+ + O2 <=> ent-sandaracopimaradien-3beta-ol + NADP + H2O
102597	3alpha-hydroxy-ent-sandaracopimardiene 9-beta-monooxygenase activity	F	Catalysis of the reaction: ent-sandaracopimaradien-3-beta-ol + NADPH + H+ + O2 <=> oryzalexin E + NADP + H2O
102598	3alpha-hydroxy-ent-sandaracopimardiene 7-beta-monooxygenase activity	F	Catalysis of the reaction: ent-sandaracopimaradien-3-beta-ol + NADPH + H+ + O2 <=> oryzalexin D + NADP + H2O
102603	12-demethyl-elloramycin C12a O-methyltransferase activity	F	Catalysis of the reaction: 12-demethyl-elloramycin + S-adenosyl-L-methionine <=> elloramycin + S-adenosyl-L-homocysteine + H+
102604	naringenin,NADPH:oxygen oxidoreductase activity	F	Catalysis of the reaction: (S)-naringenin(1-) + O2 + NADPH + H+ <=> 2-hydroxy-2,3-dihydrogenistein-7-olate + NADP + H2O
102605	cyclooctat-9-en-5,7-diol C18-monooxygenase activity	F	Catalysis of the reaction: cyclooctat-9-en-5,7-diol + O2 + NADPH + H+ <=> cyclooctatin + H2O + NADP
102606	octat-9-en-7-ol 5-monooxygenase activity	F	Catalysis of the reaction: cyclooctat-9-en-7-ol + O2 + NADPH + H+ <=> cyclooctat-9-en-5,7-diol + H2O + NADP
102607	3beta-hydroxy-12,15-cassadiene-11-one 2-hydroxylase activity	F	Catalysis of the reaction: 3beta-hydroxy-12,15-cassadiene-11-one + NADPH + O2 + H+ <=> 2beta,3beta-dihydroxy-12,15-cassadiene-11-one + NADP + H2O
102608	tetracenomycin B3 8-O-methyl transferase activity	F	Catalysis of the reaction: tetracenomycin B3 + S-adenosyl-L-methionine <=> tetracenomycin E + S-adenosyl-L-homocysteine + H+
102610	(+)-secoisolariciresinol glucosyltransferase activity	F	Catalysis of the reaction: (+)-secoisolariciresinol + UDP-alpha-D-glucose <=> (+)-secoisolariciresinol monoglucoside + UDP + H+
102611	(+)-secoisolariciresinol monoglucoside glucosyltransferase activity	F	Catalysis of the reaction: (+)-secoisolariciresinol monoglucoside + UDP-alpha-D-glucose <=> (+)-secoisolariciresinol diglucoside + UDP + H+
102612	syn-pimaradiene 6beta-hydroxylase activity	F	Catalysis of the reaction: 9beta-pimara-7,15-diene + NADPH + O2 + H+ <=> 6beta-hydroxy-syn-pimaradiene + NADP + H2O
102613	trimethyluric acid monooxygenase activity	F	Catalysis of the reaction: 1,3,7-trimethyluric acid + O2 + NADH + 3 H+ <=> 1,3,7-trimethyl-5-hydroxyisourate + NAD + H2O
102614	germacrene A acid 8beta-hydroxylase activity	F	Catalysis of the reaction: germacra-1(10),4,11(13)-trien-12-oate + NADPH + O2 + H+ <=> 8beta-hydroxy-germacra-1(10),4,11(13)-trien-12-oate + NADP + H2O
102615	ent-cassadiene-C2-hydroxylase activity	F	Catalysis of the reaction: ent-cassa-12,15-diene + NADPH + O2 + H+ <=> 2alpha-hydroxy-ent-cassadiene + NADP + H2O
102616	oryzalexin A synthase activity	F	Catalysis of the reaction: oryzalexin D + NAD(P) <=> oryzalexin A + H+ + NAD(P)H
102618	oryzalexin B synthase activity	F	Catalysis of the reaction: oryzalexin D + NAD(P) <=> oryzalexin B + H+ + NAD(P)H
102621	emindole-SB NADPH:oxygen oxidoreductase (14,15-epoxidizing) activity	F	Catalysis of the reaction: emindole-SB + O2 + NADPH + H+ <=> 14,15-epoxyemindole-SB + NADP + H2O
102622	linuron hydrolase activity	F	Catalysis of the reaction: linuron + H2O <=> N,O-dimethylhydroxylamine + carbon dioxide + 3,4-dichloroaniline
102623	scutellarein 7-methyl ether 6-O-methyltransferase activity	F	Catalysis of the reaction: scutellarein 7-methyl ether + S-adenosyl-L-methionine <=> cirsimaritin + S-adenosyl-L-homocysteine + H+
102624	scutellarein 7-methyl ether 4'-O-methyltransferase activity	F	Catalysis of the reaction: scutellarein 7-methyl ether + S-adenosyl-L-methionine <=> ladanein + S-adenosyl-L-homocysteine + H+
102625	cirsimaritin 4'-O-methyltransferase activity	F	Catalysis of the reaction: cirsimaritin + S-adenosyl-L-methionine <=> salvigenin + S-adenosyl-L-homocysteine + H+
102626	parthenolide synthase activity	F	Catalysis of the reaction: costunolide + NADPH + O2 + H+ <=> parthenolide + NADP(3-) + H2O
102627	parthenolide 3beta-hydroxylase activity	F	Catalysis of the reaction: parthenolide + NADPH + O2 + H+ <=> 3beta-hydroxyparthenolide + NADP + H2O
102628	costunolide 3beta-hydroxylase activity	F	Catalysis of the reaction: costunolide + NADPH + O2 + H+ <=> 3beta-hydroxycostunolide + NADP + H2O
102629	patuletin 3'-O-methyltransferase activity	F	Catalysis of the reaction: patuletin + S-adenosyl-L-methionine <=> quercetagetin 3',6-dimethyl ether + S-adenosyl-L-homocysteine + H+
102630	gossypetin 8-methyl ester 3'-O-methyltransferase activity	F	Catalysis of the reaction: 3',4',5,7-pentahydroxy-8-methoxyflavon-3-olate + S-adenosyl-L-methionine <=> gossypetin 3',8-dimethyl ether + S-adenosyl-L-homocysteine + H+
102631	caffeoylglucose 3-O-methyltransferase activity	F	Catalysis of the reaction: 1-O-caffeoyl-beta-D-glucose + S-adenosyl-L-methionine <=> 1-O-feruloyl-beta-D-glucose + S-adenosyl-L-homocysteine + H+
102632	(S)-nandinine synthase activity	F	Catalysis of the reaction: (S)-scoulerine + NADPH + H+ + O2 <=> (S)-nandinine + NADP + 2 H2O
102634	1,3,6,8-tetrahydroxynaphthalene monooxygenase (quinone-forming) activity	F	Catalysis of the reaction: naphthalene-1,3,6,8-tetrol + O2 <=> flaviolin-2-olate + H2O + H+
102639	paspalicine synthase activity	F	Catalysis of the reaction: 13-desoxypaxilline + NADPH + O2 + H+ <=> paspalicine + NADP + 2 H2O
102640	paspalinine synthase activity	F	Catalysis of the reaction: paspalicine + O2 + NADPH + H+ <=> paspalinine + NADP + H2O
102643	scalarane-17alpha-19-diol synthase activity	F	Catalysis of the reaction: scalarane-17alpha-19-diol <=> all-trans-geranylfarnesol + H2O
102644	monocyclic sesterterpenediol synthase activity	F	Catalysis of the reaction: monocyclic sesterterpenediol <=> all-trans-geranylfarnesol + H2O
102645	17(E)-cheilanthenediol synthase activity	F	Catalysis of the reaction: 17(E)-cheilanthenediol <=> all-trans-geranylfarnesol + H2O
102646	14betaH-scalarane-17alpha-19-diol synthase activity	F	Catalysis of the reaction: 14betaH-scalarane-17alpha-19-diol <=> all-trans-geranylfarnesol + H2O
102659	UDP-glucose: 4-methylthiobutylhydroximate S-glucosyltransferase activity	F	Catalysis of the reaction: UDP-alpha-D-glucose + 4-methylthiobutylhydroximate <=> H+ + 3-methylthiopropyl-desulfoglucosinolate + UDP
102660	caffeoyl-CoA:shikimate O-(hydroxycinnamoyl)transferase activity	F	Catalysis of the reaction: caffeoylshikimate + coenzyme A <=> caffeoyl-CoA + shikimate
102668	liquiritigenin,NADPH:oxygen oxidoreductase activity	F	Catalysis of the reaction: liquiritigenin + NADPH + O2 + H+ <=> 2,4',7-trihydroxyisoflavanone + NADP(3-) + H2O
102671	6a-hydroxymaackiain-3-O-methyltransferase activity	F	Catalysis of the reaction: (+)-6a-hydroxymaackiain + S-adenosyl-L-methionine <=> H+ + (+)-pisatin + S-adenosyl-L-homocysteine
102676	avenasterol-desaturase activity	F	Catalysis of the reaction: avenasterol + O2 + NADPH + H+ <=> 5-dehydroavenasterol + 2 H2O + NADP
102677	campesterol,NADPH:oxygen oxidoreductase activity	F	Catalysis of the reaction: H+ + campesterol + O2 + NADPH <=> (22S)-22-hydroxycampesterol + H2O + NADP
102679	(5alpha)-campestan-3-one hydroxylase activity	F	Catalysis of the reaction: H+ + (5alpha)-campestan-3-one + O2 + NADPH <=> (5alpha,22S,24R)-22-hydroxyergostan-3-one + H2O + NADP
102680	campest-4-en-3-one hydroxylase activity	F	Catalysis of the reaction: H+ + campest-4-en-3-one + O2 + NADPH <=> (22S)-22-hydroxycampest-4-en-3-one + H2O + NADP
102685	UDP-glucose:trans-zeatin 7-N-glucosyltransferase activity	F	Catalysis of the reaction: UDP-alpha-D-glucose + trans-zeatin <=> H+ + trans-zeatin-7-N-glucoside + UDP
102687	UDP-glucose:dihydrozeatin 7-N-glucosyltransferase activity	F	Catalysis of the reaction: UDP-alpha-D-glucose + dihydrozeatin <=> H+ + dihydrozeatin-7-N-glucose + UDP
102688	dihydrozeatin UDP glycosyltransferase activity	F	Catalysis of the reaction: UDP-alpha-D-glucose + dihydrozeatin <=> H+ + 9-(alpha-D-glucosyl)dihydrozeatin + UDP
102692	benzyladenine UDP glycosyltransferase activity	F	Catalysis of the reaction: UDP-alpha-D-glucose + N-benzyladenine <=> H+ + N-benzyl-9-(alpha-D-glucosyl)adenine + UDP
102695	UDP-glucose:cis-zeatin 7-N-glucosyltransferase activity	F	Catalysis of the reaction: UDP-alpha-D-glucose + cis-zeatin <=> H+ + cis-zeatin-7-N-glucoside + UDP
102698	5-epi-aristolochene synthase activity	F	Catalysis of the reaction: 2-trans,6-trans-farnesyl diphosphate <=> (+)-5-epi-aristolochene + diphosphoric acid
102699	2-methylpropionitrile hydroxylase activity	F	Catalysis of the reaction: H+ + 2-methylpropionitrile + O2 + NADPH <=> 2-hydroxy-2-methylpropanenitrile + NADP + H2O
102700	alpha-thujene synthase activity	F	Catalysis of the reaction: geranyl diphosphate(3-) <=> alpha-thujene + diphosphoric acid
102701	tricyclene synthase activity	F	Catalysis of the reaction: geranyl diphosphate(3-) <=> tricyclene + diphosphoric acid
102702	2-carene synthase activity	F	Catalysis of the reaction: geranyl diphosphate <=> (+)-2-carene + diphosphoric acid
102703	camphene synthase activity	F	Catalysis of the reaction: geranyl diphosphate <=> (-)-camphene + diphosphoric acid
102704	GDP-Man:Man2GlcNAc2-PP-dolichol alpha-1,6-mannosyltransferase activity	F	Catalysis of the reaction: GDP-alpha-D-mannose(2-) + a (mannosyl)2-(N-acetylglucosaminyl)2-diphosphodolichol <=> H+ + GDP(3-) + a (mannosyl)3-(N-acetylglucosaminyl)2-diphosphodolichol
102711	gibberellin A25,oxoglutarate:oxygen oxidoreductase activity	F	Catalysis of the reaction: gibberellin A25 + 2-oxoglutarate + O2 <=> gibberellin A13 + succinate + carbon dioxide
102712	gibberellin A13,oxoglutarate:oxygen oxidoreductase activity	F	Catalysis of the reaction: gibberellin A13 + 2-oxoglutarate + O2 <=> gibberellin A43 + succinate + carbon dioxide
102713	gibberellin A25 hydroxylase activity	F	Catalysis of the reaction: gibberellin A25 + 2-oxoglutarate(2-) + O2 <=> gibberellin A46 + succinate(2-) + carbon dioxide
102714	gibberellin A12,oxoglutarate:oxygen oxidoreductase activity	F	Catalysis of the reaction: gibberellin A12 + 2-oxoglutarate + O2 <=> gibberellin A14 + succinate + carbon dioxide
102715	gibberellin A17,oxoglutarate:oxygen oxidoreductase activity	F	Catalysis of the reaction: gibberellin A17 + 2-oxoglutarate + O2 <=> gibberellin A28 + succinate + carbon dioxide
102716	gibberellin A28,oxoglutarate:oxygen oxidoreductase activity	F	Catalysis of the reaction: gibberellin A28 + 2-oxoglutarate + O2 <=> (2betaOH)-gibberellin28 + succinate + carbon dioxide
102717	DIMBOA-glucoside oxygenase activity	F	Catalysis of the reaction: DIBOA-beta-D-glucoside + O2 + 2-oxoglutarate <=> TRIBOA-beta-D-glucoside + succinate + carbon dioxide
102718	TRIBOA-glucoside methyltransferase activity	F	Catalysis of the reaction: TRIBOA-beta-D-glucoside + S-adenosyl-L-methionine <=> (2R)-DIMBOA glucoside + S-adenosyl-L-homocysteine + H+
102730	cathasterone hydroxylase activity	F	Catalysis of the reaction: cathasterone + O2 + a reduced electron acceptor <=> teasterone + H2O + an oxidized electron acceptor
102734	brassinolide synthase activity	F	Catalysis of the reaction: H+ + castasterone + NADPH + O2 <=> brassinolide + NADP + H2O
102737	p-coumaroyltriacetic acid synthase activity	F	Catalysis of the reaction: 2 H+ + 4-coumaryl-CoA + H2O + 3 malonyl-CoA <=> 4 coenzyme A + 3 carbon dioxide + p-coumaroyltriacetate
102738	(gibberellin-14), 2-oxoglutarate:oxygen oxidoreductase activity	F	Catalysis of the reaction: gibberellin A14 + O2 + 2-oxoglutarate <=> gibberellin A37 + carbon dioxide + succinate
102739	(gibberellin-36), 2-oxoglutarate:oxygen oxidoreductase activity	F	Catalysis of the reaction: gibberellin A36 + O2 + 2-oxoglutarate <=> H+ + gibberellin A4 + succinate + 2 carbon dioxide
102740	theobromine:S-adenosyl-L-methionine 1-N-methyltransferase activity	F	Catalysis of the reaction: theobromine + S-adenosyl-L-methionine <=> H+ + caffeine + S-adenosyl-L-homocysteine
102741	paraxanthine:S-adenosyl-L-methionine 3-N-methyltransferase activity	F	Catalysis of the reaction: 1,7-dimethylxanthine + S-adenosyl-L-methionine <=> H+ + caffeine + S-adenosyl-L-homocysteine
102742	R(+)-3,4-dihydroxyphenyllactate:NADP+ oxidoreductase activity	F	Catalysis of the reaction: H+ + 3,4-dihydroxyphenylpyruvate + NADPH <=> (2R)-3-(3,4-dihydroxyphenyl)lactate + NADP
102743	eriodictyol,NADPH:oxygen oxidoreductase activity	F	Catalysis of the reaction: H+ + eriodictyol + NADPH + O2 <=> 2-(3,4-dihydroxyphenyl)-5-hydroxy-4-oxo-4H-chromen-7-olate luteolin-7-olate(1-) + NADP + 2 H2O
102747	chlorophyllide-a:geranyl-geranyl diphosphate geranyl-geranyl transferase activity	F	Catalysis of the reaction: H+ + chlorophyllide a(1-) + 2-trans,6-trans,10-trans-geranylgeranyl diphosphate(3-) <=> geranylgeranyl-chlorophyll a + diphosphoric acid
102753	chlorophyllide b:geranyl-geranyl diphosphate geranyl-geranyltransferase activity	F	Catalysis of the reaction: H+ + chlorophyllide b(1-) + 2-trans,6-trans,10-trans-geranylgeranyl diphosphate <=> geranylgeranyl-chlorophyll b + diphosphoric acid
102754	chlorophyllide-b:phytyl-diphosphate phytyltransferase activity	F	Catalysis of the reaction: H+ + chlorophyllide b + (E)-3,7,11,15-tetramethylhexadec-2-en-1-yl diphosphate <=> chlorophyll b + diphosphoric acid
102759	campestanol hydroxylase activity	F	Catalysis of the reaction: H+ + campestanol + O2 + NADPH <=> 6-deoxycathasterone + H2O + NADP
102760	6-deoxocathasterone hydroxylase activity	F	Catalysis of the reaction: 6-deoxycathasterone + O2 + a reduced electron acceptor <=> 6-deoxoteasterone + H2O + an oxidized electron acceptor
102761	eriodictyol 3'-O-methyltransferase activity	F	Catalysis of the reaction: eriodictyol + S-adenosyl-L-methionine <=> H+ + homoeriodictyol + S-adenosyl-L-homocysteine
102762	eriodictyol 4'-O-methyltransferase activity	F	Catalysis of the reaction: eriodictyol + S-adenosyl-L-methionine <=> H+ + hesperetin(1-) + S-adenosyl-L-homocysteine
102763	phytyl-P kinase activity	F	Catalysis of the reaction: phytyl phosphate(2-) + a nucleoside triphosphate <=> (E)-3,7,11,15-tetramethylhexadec-2-en-1-yl diphosphate + a nucleoside diphosphate
102766	naringenin 7-O-methyltransferase activity	F	Catalysis of the reaction: (S)-naringenin(1-) + S-adenosyl-L-methionine <=> sakuranetin + S-adenosyl-L-homocysteine + H+
102774	p-coumaroyltriacetic acid lactone synthase activity	F	Catalysis of the reaction: 2 H+ + 4-coumaryl-CoA + 3 malonyl-CoA( <=> p-coumaroyltriacetic acid lactone + 4 coenzyme A + 3 carbon dioxide
102776	UDP-D-glucose:pelargonidin-3-O-beta-D-glucoside 5-O-glucosyltransferase activity	F	Catalysis of the reaction: pelargonidin 3-O-beta-D-glucoside + UDP-alpha-D-glucose <=> anthocyanidin 3,5-di-O-beta-D-glucoside + UDP + H+
102777	caffeoyl-CoA:pelargonidin-3,5-diglucoside 5-O-glucoside-6-O-hydroxycinnamoyltransferase activity	F	Catalysis of the reaction: anthocyanidin 3,5-di-O-beta-D-glucoside + caffeoyl-CoA <=> pelargonidin-3,5-diglucoside-5-O-caffeoylglucoside + coenzyme A(4-)
102778	Delta9-tetrahydrocannabinolate synthase activity	F	Catalysis of the reaction: cannabigerolate + O2 <=> Delta(9)-tetrahydrocannabinolic acid + hydrogen peroxide
102779	cannabidiolate synthase activity	F	Catalysis of the reaction: cannabigerolate + O2 <=> cannabidiolate + hydrogen peroxide
102780	sitosterol hydroxylase activity	F	Catalysis of the reaction: H+ + sitosterol + O2 + NADPH <=> (22alpha)-hydroxy-sitosterol + H2O + NADP
102781	isofucosterol hydroxylase activity	F	Catalysis of the reaction: H+ + isofucosterol + O2 + NADPH <=> (22alpha)-hydroxy-isofucosterol + H2O + NADP
102792	sinapaldehyde:NAD(P)+ oxidoreductase activity	F	Catalysis of the reaction: sinapoyl aldehyde + NADP + H2O <=> 2 H+ + trans-sinapate + NADPH
102793	soyasapogenol glucuronosyltransferase activity	F	Catalysis of the reaction: UDP-alpha-D-glucuronate + soyasapogenol B <=> H+ + UDP + soyasapogenol B 3-O-beta-glucuronate
102796	protocatechualdehyde:oxygen oxidoreductase activity	F	Catalysis of the reaction: 3,4-dihydroxybenzaldehyde + O2 + H2O <=> H+ + 3,4-dihydroxybenzoate + hydrogen peroxide
102802	thebaine 6-O-demethylase activity	F	Catalysis of the reaction: thebaine + 2-oxoglutarate + O2 <=> neopinone + formaldehyde + succinate + carbon dioxide
102803	thebane O-demethylase activity	F	Catalysis of the reaction: thebaine + 2-oxoglutarate + O2 <=> oripavine + formaldehyde + succinate + carbon dioxide
102804	oripavine 6-O-demethylase activity	F	Catalysis of the reaction: oripavine + 2-oxoglutarate + O2 <=> morphinone + formaldehyde + succinate + carbon dioxide
102805	codeine O-demethylase activity	F	Catalysis of the reaction: codeine + 2-oxoglutarate + O2 <=> morphine + formaldehyde + succinate + carbon dioxide
103005	9,10-epoxystearate hydrolase activity	F	Catalysis of the reaction: 9,10-epoxystearate + H2O <=> (9R,10S)-dihydroxystearate
103011	mannosylfructose-phosphate synthase activity	F	Catalysis of the reaction: GDP-alpha-D-mannose + beta-D-fructofuranose 6-phosphate <=> mannosylfructose-phosphate + GDP
103019	undecaprenyl phosphate-L-Ara4FN transferase activity	F	Catalysis of the reaction: UDP-4-deoxy-4-formamido-beta-L-arabinopyranose + ditrans,polycis-undecaprenyl phosphate <=> 4-deoxy-4-formamido-alpha-L-arabinopyranosyl ditrans,polycis-undecaprenyl phosphate + UDP
103032	tartronate semialdehyde reductase activity	F	Catalysis of the reaction: D-glycerate + NAD <=> H+ + 2-hydroxy-3-oxopropanoate + NADH
103042	4-hydroxy-L-threonine aldolase activity	F	Catalysis of the reaction: 4-hydroxy-L-threonine <=> glycolaldehyde + glycine
103053	1-ethyladenine demethylase activity	F	Catalysis of the reaction: 1-ethyladenine + O2 + 2-oxoglutarate(2-) <=> adenine + carbon dioxide + acetaldehyde + succinate
103054	gibberellin A12, 2-oxoglutarate:oxygen oxidoreductase activity	F	Catalysis of the reaction: gibberellin A12 + O2 + 2-oxoglutarate <=> gibberellin A15 + carbon dioxide + succinate
103055	gibberelli A15, 2-oxoglutarate:oxygen oxidoreductase activity	F	Catalysis of the reaction: gibberellin A15 + 2-oxoglutarate + O2 <=> gibberellin A24 + succinate + carbon dioxide + H2O
103056	gibberellin A53, 2-oxoglutarate:oxygen oxidoreductase activity	F	Catalysis of the reaction: gibberellin A53 + O2 + 2-oxoglutarate <=> gibberellin A44 diacid + carbon dioxide + succinate
103057	gibberellin A19, 2-oxoglutarate:oxygen oxidoreductase activity	F	Catalysis of the reaction: gibberellin A19 + O2 + 2-oxoglutarate <=> H+ + gibberellin A20 + 2 carbon dioxide + succinate
103058	kaempferol 3-glucoside 7-O-rhamnosyltransferase activity	F	Catalysis of the reaction: kaempferol 3-O-glucoside + UDP-L-rhamnose <=> kaempferol-3-glucoside-7-rhamnoside + UDP
103059	UDP-L-rhamnose:kaempferol 3-O-rhamnosyltransferase activity	F	Catalysis of the reaction: kaempferol oxoanion + UDP-L-rhamnose <=> H+ + kaempferol-3-rhamnoside + UDP(3-)
103060	kaempferol 3-rhamnoside 7-O-rhamnosyltransferase activity	F	Catalysis of the reaction: kaempferol-3-rhamnoside + UDP-L-rhamnose <=> kaempferol-3-rhamnoside-7-rhamnoside + UDP.
103061	trans-methoxy-C60-meroacyl-AMP ligase activity	F	Catalysis of the reaction: ATP(4-) + H2O + a trans-methoxy-C60-meroacyl-[acp] <=> diphosphoric acid + a trans-methoxy-meroacyl-adenylate + a holo-[acyl-carrier protein]
103062	cis-keto-C60-meroacyl-AMP ligase activity	F	Catalysis of the reaction: ATP(4-) + H2O + a cis-keto-C60-meroacyl-[acp] <=> diphosphoric acid + a cis-keto-meroacyl-adenylate + a holo-[acyl-carrier protein]
103063	trans-keto-C61-meroacyl-AMP ligase activity	F	Catalysis of the reaction: ATP(4-) + H2O + a trans-keto-C61-meroacyl-[acp] <=> diphosphoric acid + a trans-keto-meroacyl-adenylate + a holo-[acyl-carrier protein]
103069	17-hydroxyprogesterone 21-hydroxylase activity	F	Catalysis of the reaction: 17alpha-hydroxyprogesterone + NADPH + H+ + O2 <=> NADP + H2O + 11-deoxycortisol
103073	anandamide amidohydrolase activity	F	Catalysis of the reaction: anandamide + H2O <=> arachidonate + ethanolaminium(1+)
103075	indole-3-pyruvate monooxygenase activity	F	Catalysis of the reaction: 3-(indol-3-yl)pyruvate + NADPH + O2 + H+ <=> indole-3-acetate + carbon dioxide + NADP + H2O
103077	quercetin 3-glucoside 7-O-rhamnosyltransferase activity	F	Catalysis of the reaction: quercetin-3-glucoside + UDP-L-rhamnose <=> quercetin-3-O-glucoside-7-O-rhamnoside + UDP(3-)
103078	quercetin 3-rhamnoside 7-O-rhamnosyltransferase activity	F	Catalysis of the reaction: H+ + quercetin 3-O-rhamnoside + UDP-L-rhamnose <=> quercetin-3-rhamnoside-7-rhamnoside + UDP(3-)
103079	2-(3'-methylthio)propylmalate synthase activity	F	Catalysis of the reaction: 5-methylthio-2-oxopentanoate + acetyl-CoA(4-) + H2O <=> H+ + 2-(3-methylthiopropyl)malate(2-) + coenzyme A(4-)
103082	2-(4'-methylthio)butylmalate synthase activity	F	Catalysis of the reaction: 2-oxo-6-methylthiohexanoate + acetyl-CoA(4-) + H2O <=> H+ + 2-(4'-methylthio)butylmalate + coenzyme A(4-)
103085	2-(5'-methylthio)pentylmalate synthase activity	F	Catalysis of the reaction: 2-oxo-7-methylthioheptanoate + acetyl-CoA(4-) + H2O <=> H+ + 2-(5'-methylthio)pentylmalate + coenzyme A(4-)
103088	2-(6'-methylthio)hexylmalate synthase activity	F	Catalysis of the reaction: 2-oxo-8-methylthiooctanoate + acetyl-CoA(4-) + H2O <=> H+ + 2-(6'-methylthio)hexylmalate + coenzyme A(4-)
103091	2-(7'-methylthio)heptylmalate synthase activity	F	Catalysis of the reaction: 2-oxo-9-methylthiononanoate + acetyl-CoA(4-) + H2O <=> H+ + 2-(7'-methylthio)heptylmalate + coenzyme A(4-)
103092	methylthioalkylmalate isomerase activity	F	Catalysis of the reaction: 2-(7'-methylthio)heptylmalate <=> 3-(7'-methylthio)heptylmalate
103093	methylthioalkylmalate dehydrogenase activity	F	Catalysis of the reaction: 3-(7'-methylthio)heptylmalate <=> H+ + 2-oxo-10-methylthiodecanoate + carbon dioxide
103095	wax ester synthase activity	F	Catalysis of the reaction: a very long chain alcohol + a long-chain acyl-CoA <=> coenzyme A(4-) + a wax ester
103096	CYP79F1 dihomomethionine monooxygenase activity	F	Catalysis of the reaction: dihomomethionine + 2 O2 + 2 NADPH(4-) + 2 H+ <=> 5-methylthiopentanaldoxime + 3 H2O + carbon dioxide + 2 NADP(3-)
103097	CYP79F1 trihomomethionine monooxygenase activity	F	Catalysis of the reaction: trihomomethionine + 2 O2 + 2 NADPH(4-) + 2 H+ <=> 3 H2O + carbon dioxide + 2 NADP(3-) + 6-methylthiohexanaldoxime
103098	CYP79F1 tetrahomomethionine monooxygenase activity	F	Catalysis of the reaction: 2 H+ + tetrahomomethionine + 2 O2 + 2 NADPH(4-) <=> 3 H2O + carbon dioxide + 2 NADP(3-) + 7-methylthioheptanaldoxime
103099	UDP-glucose:5-methylthiopentylhydroximate S-glucosyltransferase activity	F	Catalysis of the reaction: UDP-alpha-D-glucose(2-) + 5-methylthiopentylhydroximate <=> H+ + 4-methylthiobutyldesulfoglucosinolate + UDP(3-)
103100	UDP-glucose: 6-methylthiohexylhydroximate S-glucosyltransferase activity	F	Catalysis of the reaction: UDP-alpha-D-glucose(2-) + 6-methylthiohexylhydroximate <=> H+ + 5-methylthiopentyldesulfoglucosinolate + UDP(3-)
103101	UDP-glucose:7-methylthioheptylhydroximate S-glucosyltransferase activity	F	Catalysis of the reaction: UDP-alpha-D-glucose(2-) + 7-methylthioheptylhydroximate <=> H+ + 6-methylthiohexyldesulfoglucosinolate + UDP(3-)
103102	UDP-glucose:8-methylthiooctylhydroximate S-glucosyltransferase activity	F	Catalysis of the reaction: UDP-alpha-D-glucose(2-) + 8-methylthiooctylhydroximate <=> H+ + 7-methylthioheptyldesulfoglucosinolate + UDP(3-)
103103	UDP-glucose: 9-methylthiononylhydroximate S-glucosyltransferase activity	F	Catalysis of the reaction: UDP-alpha-D-glucose(2-) + 9-methylthiononylhydroximate <=> 8-methylthiooctyldesulfoglucosinolate + UDP(3-) + H+
103104	6-methylthiohexyldesulfoglucosinolate sulfotransferase activity	F	Catalysis of the reaction: 6-methylthiohexyldesulfoglucosinolate + 3'-phosphonato-5'-adenylyl sulfate(4-) <=> adenosine 3',5'-bismonophosphate(4-) + H+ + 6-methylthiohexylglucosinolate
103105	2-oxo-6-methylthiohexanoate aminotransferase activity	F	Catalysis of the reaction: 2-oxo-6-methylthiohexanoate + a standard alpha amino acid <=> dihomomethionine + a 2-oxo carboxylate
103106	brassinolide 23-O-glucosyltransferase activity	F	Catalysis of the reaction: brassinolide + UDP-alpha-D-glucose(2-) <=> brassinolide-23-O-glucoside + UDP(3-) + H+
103107	castasterone 23-O-glucosyltransferase activity	F	Catalysis of the reaction: castasterone + UDP-alpha-D-glucose(2-) <=> castasterone-23-O-glucoside + UDP(3-) + H+
103111	D-glucosamine PTS permease activity	F	Catalysis of the reaction: a [PTS enzyme I]-Npi-phospho-L-histidine + D-glucosamine <=> D-glucosamine 6-phosphate + a [PTS enzyme I]-L-histidine
103113	glucosyl-oleandomycin-exporting ATPase activity	F	Catalysis of the reaction: glucosyl-oleandomycin + ATP(4-) + H2O <=> glucosyl-oleandomycin + ADP(3-) + hydrogenphosphate + H+
103115	protoheme IX ABC transporter activity	F	Catalysis of the reaction: ATP(4-) + H2O + heme b <=> hydrogenphosphate + ADP(3-) + H+ + heme b
103116	alpha-D-galactofuranose transporter activity	F	Catalysis of the reaction: alpha-D-galactofuranose + ATP(4-) + H2O <=> alpha-D-galactofuranose + hydrogenphosphate + ADP(3-) + H+
103117	UDP-3-O-acyl-N-acetylglucosamine deacetylase activity	F	Catalysis of the reaction: UDP-3-O-[(3R)-3-hydroxytetradecanoyl]-N-acetylglucosamine(2-) + H2O <=> UDP-3-O-[(3R)-3-hydroxytetradecanoyl]-alpha-D-glucosamine(1-) + acetate
103118	UDP-3-O-(R-3-hydroxymyristoyl)-glucosamine N-acyltransferase activity	F	Catalysis of the reaction: UDP-3-O-[(3R)-3-hydroxytetradecanoyl]-alpha-D-glucosamine(1-) + an (3R)-3-hydroxymyristoyl-[acp] <=> UDP-2,3-bis[O-(3R)-3-hydroxymyristoyl]-alpha-D-glucosamine + H+ + a holo-[acyl-carrier protein]
198738	cell-cell signaling by wnt	P	Any process that mediates the transfer of information from one cell to another, medaited by a wnt family protein ligand. This process includes wnt signal transduction in the receiving cell, release of wnt ligand from a secreting cell as well as any processes that actively facilitate wnt transport and presentation to receptor on the recieving cell.
1900000	regulation of anthocyanin catabolic process	P	Any process that modulates the frequency, rate or extent of anthocyanin catabolic process.
1900001	negative regulation of anthocyanin catabolic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of anthocyanin catabolic process.
1900002	positive regulation of anthocyanin catabolic process	P	Any process that activates or increases the frequency, rate or extent of anthocyanin catabolic process.
1900003	regulation of serine-type endopeptidase activity	P	Any process that modulates the frequency, rate or extent of serine-type endopeptidase activity.
1900004	negative regulation of serine-type endopeptidase activity	P	Any process that stops, prevents or reduces the frequency, rate or extent of serine-type endopeptidase activity.
1900005	positive regulation of serine-type endopeptidase activity	P	Any process that activates or increases the frequency, rate or extent of serine-type endopeptidase activity.
1900006	positive regulation of dendrite development	P	Any process that activates or increases the frequency, rate or extent of dendrite development.
1900007	regulation of extrachromosomal rDNA circle accumulation involved in replicative cell aging	P	Any process that modulates the frequency, rate or extent of extrachromosomal rDNA circle accumulation involved in replicative cell aging.
1900008	negative regulation of extrachromosomal rDNA circle accumulation involved in replicative cell aging	P	Any process that stops, prevents or reduces the frequency, rate or extent of extrachromosomal rDNA circle accumulation involved in replicative cell aging.
1900009	positive regulation of extrachromosomal rDNA circle accumulation involved in replicative cell aging	P	Any process that activates or increases the frequency, rate or extent of extrachromosomal rDNA circle accumulation involved in replicative cell aging.
1900010	regulation of corticotropin-releasing hormone receptor activity	P	Any process that modulates the frequency, rate or extent of corticotropin-releasing hormone receptor activity.
1900011	negative regulation of corticotropin-releasing hormone receptor activity	P	Any process that stops, prevents or reduces the frequency, rate or extent of corticotropin-releasing hormone receptor activity.
1900012	positive regulation of corticotropin-releasing hormone receptor activity	P	Any process that activates or increases the frequency, rate or extent of corticotropin-releasing hormone receptor activity.
1900015	regulation of cytokine production involved in inflammatory response	P	Any process that modulates the frequency, rate or extent of cytokine production involved in inflammatory response.
1900016	negative regulation of cytokine production involved in inflammatory response	P	Any process that stops, prevents or reduces the frequency, rate or extent of cytokine production involved in inflammatory response.
1900017	positive regulation of cytokine production involved in inflammatory response	P	Any process that activates or increases the frequency, rate or extent of cytokine production involved in inflammatory response.
1900018	phosphorylation of RNA polymerase II C-terminal domain serine 5 residues involved in recruitment of mRNA capping enzyme to RNA polymerase II holoenzyme complex	P	Any phosphorylation of RNA polymerase II C-terminal domain serine 5 residues that is involved in recruitment of mRNA capping enzyme to RNA polymerase II holoenzyme complex.
1900019	regulation of protein kinase C activity	P	Any process that modulates the frequency, rate or extent of protein kinase C activity.
1900020	positive regulation of protein kinase C activity	P	Any process that activates or increases the frequency, rate or extent of protein kinase C activity.
1900022	regulation of D-erythro-sphingosine kinase activity	P	Any process that modulates the frequency, rate or extent of D-erythro-sphingosine kinase activity.
1900023	positive regulation of D-erythro-sphingosine kinase activity	P	Any process that activates or increases the frequency, rate or extent of D-erythro-sphingosine kinase activity.
1900024	regulation of substrate adhesion-dependent cell spreading	P	Any process that modulates the frequency, rate or extent of substrate adhesion-dependent cell spreading.
1900025	negative regulation of substrate adhesion-dependent cell spreading	P	Any process that stops, prevents or reduces the frequency, rate or extent of substrate adhesion-dependent cell spreading.
1900026	positive regulation of substrate adhesion-dependent cell spreading	P	Any process that activates or increases the frequency, rate or extent of substrate adhesion-dependent cell spreading.
1900027	regulation of ruffle assembly	P	Any process that modulates the frequency, rate or extent of ruffle assembly.
1900028	negative regulation of ruffle assembly	P	Any process that stops, prevents or reduces the frequency, rate or extent of ruffle assembly.
1900029	positive regulation of ruffle assembly	P	Any process that activates or increases the frequency, rate or extent of ruffle assembly.
1900030	regulation of pectin biosynthetic process	P	Any process that modulates the frequency, rate or extent of pectin biosynthetic process.
1900032	regulation of trichome patterning	P	Any process that modulates the frequency, rate or extent of trichome patterning.
1900033	negative regulation of trichome patterning	P	Any process that stops, prevents or reduces the frequency, rate or extent of trichome patterning.
1900034	regulation of cellular response to heat	P	Any process that modulates the frequency, rate or extent of cellular response to heat.
1900035	negative regulation of cellular response to heat	P	Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to heat.
1900036	positive regulation of cellular response to heat	P	Any process that activates or increases the frequency, rate or extent of cellular response to heat.
1900037	regulation of cellular response to hypoxia	P	Any process that modulates the frequency, rate or extent of cellular response to hypoxia.
1900038	negative regulation of cellular response to hypoxia	P	Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to hypoxia.
1900039	positive regulation of cellular response to hypoxia	P	Any process that activates or increases the frequency, rate or extent of cellular response to hypoxia.
1900040	regulation of interleukin-2 secretion	P	Any process that modulates the frequency, rate or extent of interleukin-2 secretion.
1900041	negative regulation of interleukin-2 secretion	P	Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-2 secretion.
1900042	positive regulation of interleukin-2 secretion	P	Any process that activates or increases the frequency, rate or extent of interleukin-2 secretion.
1900044	regulation of protein K63-linked ubiquitination	P	Any process that modulates the frequency, rate or extent of protein K63-linked ubiquitination.
1900045	negative regulation of protein K63-linked ubiquitination	P	Any process that stops, prevents or reduces the frequency, rate or extent of protein K63-linked ubiquitination.
1900046	regulation of hemostasis	P	Any process that modulates the frequency, rate or extent of hemostasis.
1900047	negative regulation of hemostasis	P	Any process that stops, prevents or reduces the frequency, rate or extent of hemostasis.
1900048	positive regulation of hemostasis	P	Any process that activates or increases the frequency, rate or extent of hemostasis.
1900049	regulation of histone exchange	P	Any process that modulates the frequency, rate or extent of histone exchange.
1900050	negative regulation of histone exchange	P	Any process that stops, prevents or reduces the frequency, rate or extent of histone exchange.
1900051	positive regulation of histone exchange	P	Any process that activates or increases the frequency, rate or extent of histone exchange.
1900052	regulation of retinoic acid biosynthetic process	P	Any process that modulates the frequency, rate or extent of retinoic acid biosynthetic process.
1900053	negative regulation of retinoic acid biosynthetic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of retinoic acid biosynthetic process.
1900054	positive regulation of retinoic acid biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of retinoic acid biosynthetic process.
1900055	regulation of leaf senescence	P	Any process that modulates the frequency, rate or extent of leaf senescence.
1900056	negative regulation of leaf senescence	P	Any process that stops, prevents or reduces the frequency, rate or extent of leaf senescence.
1900057	positive regulation of leaf senescence	P	Any process that activates or increases the frequency, rate or extent of leaf senescence.
1900058	regulation of sulfate assimilation	P	Any process that modulates the frequency, rate or extent of sulfate assimilation.
1900059	positive regulation of sulfate assimilation	P	Any process that activates or increases the frequency, rate or extent of sulfate assimilation.
1900060	negative regulation of ceramide biosynthetic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of a ceramide biosynthetic process.
1900062	regulation of replicative cell aging	P	Any process that modulates the frequency, rate or extent of replicative cell aging.
1900063	regulation of peroxisome organization	P	Any process that modulates the frequency, rate or extent of peroxisome organization.
1900064	positive regulation of peroxisome organization	P	Any process that activates or increases the frequency, rate or extent of peroxisome organization.
1900065	regulation of ethanol catabolic process	P	Any process that modulates the frequency, rate or extent of ethanol catabolic process.
1900066	positive regulation of ethanol catabolic process	P	Any process that activates or increases the frequency, rate or extent of ethanol catabolic process.
1900067	regulation of cellular response to alkaline pH	P	Any process that modulates the frequency, rate or extent of cellular response to alkalinity.
1900068	negative regulation of cellular response to alkaline pH	P	Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to alkalinity.
1900069	regulation of cellular hyperosmotic salinity response	P	Any process that modulates the frequency, rate or extent of cellular hyperosmotic salinity response.
1900070	negative regulation of cellular hyperosmotic salinity response	P	Any process that stops, prevents or reduces the frequency, rate or extent of cellular hyperosmotic salinity response.
1900071	regulation of sulfite transport	P	Any process that modulates the frequency, rate or extent of sulfite transport.
1900072	positive regulation of sulfite transport	P	Any process that activates or increases the frequency, rate or extent of sulfite transport.
1900073	regulation of neuromuscular synaptic transmission	P	Any process that modulates the frequency, rate or extent of neuromuscular synaptic transmission.
1900074	negative regulation of neuromuscular synaptic transmission	P	Any process that stops, prevents or reduces the frequency, rate or extent of neuromuscular synaptic transmission.
1900075	positive regulation of neuromuscular synaptic transmission	P	Any process that activates or increases the frequency, rate or extent of neuromuscular synaptic transmission.
1900076	regulation of cellular response to insulin stimulus	P	Any process that modulates the frequency, rate or extent of cellular response to insulin stimulus.
1900077	negative regulation of cellular response to insulin stimulus	P	Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to insulin stimulus.
1900078	positive regulation of cellular response to insulin stimulus	P	Any process that activates or increases the frequency, rate or extent of cellular response to insulin stimulus.
1900079	regulation of arginine biosynthetic process	P	Any process that modulates the frequency, rate or extent of arginine biosynthetic process.
1900080	positive regulation of arginine biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of arginine biosynthetic process.
1900081	regulation of arginine catabolic process	P	Any process that modulates the frequency, rate or extent of arginine catabolic process.
1900082	negative regulation of arginine catabolic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of arginine catabolic process.
1900084	regulation of peptidyl-tyrosine autophosphorylation	P	Any process that modulates the frequency, rate or extent of peptidyl-tyrosine autophosphorylation.
1900085	negative regulation of peptidyl-tyrosine autophosphorylation	P	Any process that stops, prevents or reduces the frequency, rate or extent of peptidyl-tyrosine autophosphorylation.
1900086	positive regulation of peptidyl-tyrosine autophosphorylation	P	Any process that activates or increases the frequency, rate or extent of peptidyl-tyrosine autophosphorylation.
1900087	positive regulation of G1/S transition of mitotic cell cycle	P	Any cell cycle regulatory process that promotes the commitment of a cell from G1 to S phase of the mitotic cell cycle.
1900088	regulation of inositol biosynthetic process	P	Any process that modulates the frequency, rate or extent of inositol biosynthetic process.
1900089	negative regulation of inositol biosynthetic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of inositol biosynthetic process.
1900090	positive regulation of inositol biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of inositol biosynthetic process.
1900091	regulation of raffinose biosynthetic process	P	Any process that modulates the frequency, rate or extent of raffinose biosynthetic process.
1900092	negative regulation of raffinose biosynthetic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of raffinose biosynthetic process.
1900093	positive regulation of raffinose biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of raffinose biosynthetic process.
1900094	regulation of transcription from RNA polymerase II promoter involved in determination of left/right symmetry	P	Any regulation of transcription from RNA polymerase II promoter that is involved in determination of left/right symmetry.
1900095	regulation of dosage compensation by inactivation of X chromosome	P	Any process that modulates the frequency, rate or extent of dosage compensation, by inactivation of X chromosome.
1900096	negative regulation of dosage compensation by inactivation of X chromosome	P	Any process that stops, prevents or reduces the frequency, rate or extent of dosage compensation, by inactivation of X chromosome.
1900097	positive regulation of dosage compensation by inactivation of X chromosome	P	Any process that activates or increases the frequency, rate or extent of dosage compensation, by inactivation of X chromosome.
1900098	regulation of plasma cell differentiation	P	Any process that modulates the frequency, rate or extent of plasma cell differentiation.
1900099	negative regulation of plasma cell differentiation	P	Any process that stops, prevents or reduces the frequency, rate or extent of plasma cell differentiation.
1900100	positive regulation of plasma cell differentiation	P	Any process that activates or increases the frequency, rate or extent of plasma cell differentiation.
1900101	regulation of endoplasmic reticulum unfolded protein response	P	Any process that modulates the frequency, rate or extent of endoplasmic reticulum unfolded protein response.
1900102	negative regulation of endoplasmic reticulum unfolded protein response	P	Any process that stops, prevents or reduces the frequency, rate or extent of endoplasmic reticulum unfolded protein response.
1900103	positive regulation of endoplasmic reticulum unfolded protein response	P	Any process that activates or increases the frequency, rate or extent of endoplasmic reticulum unfolded protein response.
1900104	regulation of hyaluranon cable assembly	P	Any process that modulates the frequency, rate or extent of hyaluranon cable assembly.
1900105	negative regulation of hyaluranon cable assembly	P	Any process that stops, prevents or reduces the frequency, rate or extent of hyaluranon cable assembly.
1900106	positive regulation of hyaluranon cable assembly	P	Any process that activates or increases the frequency, rate or extent of hyaluranon cable assembly.
1900107	regulation of nodal signaling pathway	P	Any process that modulates the frequency, rate or extent of nodal signaling pathway.
1900108	negative regulation of nodal signaling pathway	P	Any process that stops, prevents or reduces the frequency, rate or extent of nodal signaling pathway.
1900109	regulation of histone H3-K9 dimethylation	P	Any process that modulates the frequency, rate or extent of histone H3-K9 dimethylation.
1900110	negative regulation of histone H3-K9 dimethylation	P	Any process that stops, prevents or reduces the frequency, rate or extent of histone H3-K9 dimethylation.
1900111	positive regulation of histone H3-K9 dimethylation	P	Any process that activates or increases the frequency, rate or extent of histone H3-K9 dimethylation.
1900112	regulation of histone H3-K9 trimethylation	P	Any process that modulates the frequency, rate or extent of histone H3-K9 trimethylation.
1900113	negative regulation of histone H3-K9 trimethylation	P	Any process that stops, prevents or reduces the frequency, rate or extent of histone H3-K9 trimethylation.
1900114	positive regulation of histone H3-K9 trimethylation	P	Any process that activates or increases the frequency, rate or extent of histone H3-K9 trimethylation.
1900115	extracellular regulation of signal transduction	P	Any regulation of signal transduction that takes place in the extracellular region.
1900116	extracellular negative regulation of signal transduction	P	Any negative regulation of signal transduction that takes place in extracellular region.
1900117	regulation of execution phase of apoptosis	P	Any process that modulates the frequency, rate or extent of execution phase of apoptosis.
1900118	negative regulation of execution phase of apoptosis	P	Any process that stops, prevents or reduces the frequency, rate or extent of execution phase of apoptosis.
1900119	positive regulation of execution phase of apoptosis	P	Any process that activates or increases the frequency, rate or extent of execution phase of apoptosis.
1900120	regulation of receptor binding	P	Any process that modulates the frequency, rate or extent of a protein or other molecule binding to a receptor.
1900121	negative regulation of receptor binding	P	Any process that stops, prevents or reduces the frequency, rate or extent of a protein or other molecule binding to a receptor.
1900122	positive regulation of receptor binding	P	Any process that activates or increases the frequency, rate or extent of a protein or other molecule binding to a receptor.
1900123	regulation of nodal receptor complex assembly	P	Any process that modulates the frequency, rate or extent of nodal receptor complex assembly.
1900124	negative regulation of nodal receptor complex assembly	P	Any process that stops, prevents or reduces the frequency, rate or extent of nodal receptor complex assembly.
1900125	regulation of hyaluronan biosynthetic process	P	Any process that modulates the frequency, rate or extent of hyaluronan biosynthetic process.
1900126	negative regulation of hyaluronan biosynthetic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of hyaluronan biosynthetic process.
1900127	positive regulation of hyaluronan biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of hyaluronan biosynthetic process.
1900128	regulation of G-protein activated inward rectifier potassium channel activity	P	Any process that modulates the frequency, rate or extent of G-protein activated inward rectifier potassium channel activity.
1900129	positive regulation of G-protein activated inward rectifier potassium channel activity	P	Any process that activates or increases the frequency, rate or extent of G-protein activated inward rectifier potassium channel activity.
1900130	regulation of lipid binding	P	Any process that modulates the frequency, rate or extent of lipid binding.
1900131	negative regulation of lipid binding	P	Any process that stops, prevents or reduces the frequency, rate or extent of lipid binding.
1900132	positive regulation of lipid binding	P	Any process that activates or increases the frequency, rate or extent of lipid binding.
1900133	regulation of renin secretion into blood stream	P	Any process that modulates the frequency, rate or extent of renin secretion into blood stream.
1900134	negative regulation of renin secretion into blood stream	P	Any process that stops, prevents or reduces the frequency, rate or extent of renin secretion into blood stream.
1900135	positive regulation of renin secretion into blood stream	P	Any process that activates or increases the frequency, rate or extent of renin secretion into blood stream.
1900136	regulation of chemokine activity	P	Any process that modulates the frequency, rate or extent of chemokine activity.
1900137	negative regulation of chemokine activity	P	Any process that stops, prevents or reduces the frequency, rate or extent of chemokine activity.
1900138	negative regulation of phospholipase A2 activity	P	Any process that stops, prevents or reduces the frequency, rate or extent of phospholipase A2 activity.
1900139	negative regulation of arachidonic acid secretion	P	Any process that stops, prevents or reduces the frequency, rate or extent of arachidonic acid secretion.
1900140	regulation of seedling development	P	Any process that modulates the frequency, rate or extent of seedling development.
1900141	regulation of oligodendrocyte apoptotic process	P	Any process that modulates the frequency, rate or extent of oligodendrocyte apoptotic process.
1900142	negative regulation of oligodendrocyte apoptotic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of oligodendrocyte apoptotic process.
1900143	positive regulation of oligodendrocyte apoptotic process	P	Any process that activates or increases the frequency, rate or extent of oligodendrocyte apoptotic process.
1900144	positive regulation of BMP secretion	P	Any process that activates or increases the frequency, rate or extent of BMP secretion.
1900145	regulation of nodal signaling pathway involved in determination of left/right asymmetry	P	Any process that modulates the frequency, rate or extent of a nodal signaling pathway, where the nodal signaling pathway is involved in determination of left/right asymmetry.
1900146	negative regulation of nodal signaling pathway involved in determination of left/right asymmetry	P	Any process that stops, prevents or reduces the frequency, rate or extent of a nodal signaling pathway, where the nodal signaling pathway is involved in determination of left/right asymmetry.
1900147	regulation of Schwann cell migration	P	Any process that modulates the frequency, rate or extent of Schwann cell migration.
1900148	negative regulation of Schwann cell migration	P	Any process that stops, prevents or reduces the frequency, rate or extent of Schwann cell migration.
1900149	positive regulation of Schwann cell migration	P	Any process that activates or increases the frequency, rate or extent of Schwann cell migration.
1900150	regulation of defense response to fungus	P	Any process that modulates the frequency, rate or extent of defense response to fungus.
1900151	regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	P	Any process that modulates the frequency, rate or extent of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay.
1900152	negative regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	P	Any process that stops, prevents or reduces the frequency, rate or extent of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay.
1900153	positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay	P	Any process that activates or increases the frequency, rate or extent of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay.
1900154	regulation of bone trabecula formation	P	Any process that modulates the frequency, rate or extent of bone trabecula formation.
1900155	negative regulation of bone trabecula formation	P	Any process that stops, prevents or reduces the frequency, rate or extent of bone trabecula formation.
1900156	positive regulation of bone trabecula formation	P	Any process that activates or increases the frequency, rate or extent of bone trabecula formation.
1900157	regulation of bone mineralization involved in bone maturation	P	Any process that modulates the frequency, rate or extent of bone mineralization involved in bone maturation.
1900158	negative regulation of bone mineralization involved in bone maturation	P	Any process that stops, prevents or reduces the frequency, rate or extent of bone mineralization involved in bone maturation.
1900159	positive regulation of bone mineralization involved in bone maturation	P	Any process that activates or increases the frequency, rate or extent of bone mineralization involved in bone maturation.
1900160	plastid DNA packaging	P	Any process in which plastidial DNA and associated proteins are formed into a compact, orderly structure.
1900161	regulation of phospholipid scramblase activity	P	Any process that modulates the frequency, rate or extent of phospholipid scramblase activity.
1900162	negative regulation of phospholipid scramblase activity	P	Any process that stops, prevents or reduces the frequency, rate or extent of phospholipid scramblase activity.
1900163	positive regulation of phospholipid scramblase activity	P	Any process that activates or increases the frequency, rate or extent of phospholipid scramblase activity.
1900164	nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry	P	A series of molecular signals initiated by the binding of a nodal protein to an activin receptor on the surface of a target cell, which contributes to the establishment of lateral mesoderm with respect to the left and right halves.
1900165	negative regulation of interleukin-6 secretion	P	Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-6 secretion.
1900166	regulation of glial cell-derived neurotrophic factor secretion	P	Any process that modulates the frequency, rate or extent of glial cell-derived neurotrophic factor secretion.
1900167	negative regulation of glial cell-derived neurotrophic factor secretion	P	Any process that stops, prevents or reduces the frequency, rate or extent of glial cell-derived neurotrophic factor secretion.
1900168	positive regulation of glial cell-derived neurotrophic factor secretion	P	Any process that activates or increases the frequency, rate or extent of glial cell-derived neurotrophic factor secretion.
1900169	regulation of glucocorticoid mediated signaling pathway	P	Any process that modulates the frequency, rate or extent of glucocorticoid mediated signaling pathway.
1900170	negative regulation of glucocorticoid mediated signaling pathway	P	Any process that stops, prevents or reduces the frequency, rate or extent of glucocorticoid mediated signaling pathway.
1900171	positive regulation of glucocorticoid mediated signaling pathway	P	Any process that activates or increases the frequency, rate or extent of glucocorticoid mediated signaling pathway.
1900175	regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry	P	Any process that modulates the frequency, rate or extent of a nodal signaling pathway, where the nodal signaling pathway is involved in determination of left/right asymmetry in the lateral mesoderm.
1900176	negative regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry	P	Any process that stops, prevents or reduces the frequency, rate or extent of a nodal signaling pathway, where the nodal signaling pathway is involved in determination of left/right asymmetry in the lateral mesoderm.
1900177	regulation of aflatoxin biosynthetic process	P	Any process that modulates the frequency, rate or extent of aflatoxin biosynthetic process.
1900178	negative regulation of aflatoxin biosynthetic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of aflatoxin biosynthetic process.
1900179	positive regulation of aflatoxin biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of aflatoxin biosynthetic process.
1900180	regulation of protein localization to nucleus	P	Any process that modulates the frequency, rate or extent of protein localization to nucleus.
1900181	negative regulation of protein localization to nucleus	P	Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to nucleus.
1900182	positive regulation of protein localization to nucleus	P	Any process that activates or increases the frequency, rate or extent of protein localization to nucleus.
1900183	regulation of xanthone-containing compound biosynthetic process	P	Any process that modulates the frequency, rate or extent of xanthone-containing compound biosynthetic process.
1900184	negative regulation of xanthone-containing compound biosynthetic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of xanthone-containing compound biosynthetic process.
1900185	positive regulation of xanthone-containing compound biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of xanthone-containing compound biosynthetic process.
1900186	negative regulation of clathrin-dependent endocytosis	P	Any process that stops, prevents or reduces the frequency, rate or extent of clathrin-mediated endocytosis.
1900187	regulation of cell adhesion involved in single-species biofilm formation	P	Any process that modulates the frequency, rate or extent of cell adhesion involved in single-species biofilm formation.
1900188	negative regulation of cell adhesion involved in single-species biofilm formation	P	Any process that stops, prevents or reduces the frequency, rate or extent of cell adhesion involved in single-species biofilm formation.
1900189	positive regulation of cell adhesion involved in single-species biofilm formation	P	Any process that activates or increases the frequency, rate or extent of cell adhesion involved in single-species biofilm formation.
1900190	regulation of single-species biofilm formation	P	Any process that modulates the frequency, rate or extent of single-species biofilm formation.
1900191	negative regulation of single-species biofilm formation	P	Any process that stops, prevents or reduces the frequency, rate or extent of single-species biofilm formation.
1900192	positive regulation of single-species biofilm formation	P	Any process that activates or increases the frequency, rate or extent of single-species biofilm formation.
1900193	regulation of oocyte maturation	P	Any process that modulates the frequency, rate or extent of oocyte maturation.
1900194	negative regulation of oocyte maturation	P	Any process that stops, prevents or reduces the frequency, rate or extent of oocyte maturation.
1900195	positive regulation of oocyte maturation	P	Any process that activates or increases the frequency, rate or extent of oocyte maturation.
1900196	regulation of penicillin biosynthetic process	P	Any process that modulates the frequency, rate or extent of penicillin biosynthetic process.
1900197	negative regulation of penicillin biosynthetic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of penicillin biosynthetic process.
1900198	positive regulation of penicillin biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of penicillin biosynthetic process.
1900199	positive regulation of protein export from nucleus during meiotic anaphase II	P	Any process that activates or increases the frequency, rate or extent of directed movement of proteins from the nucleus into the cytoplasm, during anaphase occurring as part of meiosis II.
1900200	mesenchymal cell apoptotic process involved in metanephros development	P	Any mesenchymal cell apoptotic process that is involved in metanephros development.
1900204	apoptotic process involved in metanephric collecting duct development	P	Any apoptotic process that is involved in metanephric collecting duct development.
1900205	apoptotic process involved in metanephric nephron tubule development	P	Any apoptotic process that is involved in metanephric nephron tubule development.
1900206	regulation of pronephric nephron tubule development	P	Any process that modulates the frequency, rate or extent of pronephric nephron tubule development.
1900207	negative regulation of pronephric nephron tubule development	P	Any process that stops, prevents or reduces the frequency, rate or extent of pronephric nephron tubule development.
1900208	regulation of cardiolipin metabolic process	P	Any process that modulates the frequency, rate or extent of cardiolipin metabolic process.
1900209	negative regulation of cardiolipin metabolic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of cardiolipin metabolic process.
1900210	positive regulation of cardiolipin metabolic process	P	Any process that activates or increases the frequency, rate or extent of cardiolipin metabolic process.
1900211	regulation of mesenchymal cell apoptotic process involved in metanephros development	P	Any process that modulates the frequency, rate or extent of mesenchymal cell apoptotic process involved in metanephros development.
1900212	negative regulation of mesenchymal cell apoptotic process involved in metanephros development	P	Any process that stops, prevents or reduces the frequency, rate or extent of mesenchymal cell apoptotic process involved in metanephros development.
1900213	positive regulation of mesenchymal cell apoptotic process involved in metanephros development	P	Any process that activates or increases the frequency, rate or extent of mesenchymal cell apoptotic process involved in metanephros development.
1900214	regulation of apoptotic process involved in metanephric collecting duct development	P	Any process that modulates the frequency, rate or extent of apoptotic process involved in metanephric collecting duct development.
1900215	negative regulation of apoptotic process involved in metanephric collecting duct development	P	Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic process involved in metanephric collecting duct development.
1900216	positive regulation of apoptotic process involved in metanephric collecting duct development	P	Any process that activates or increases the frequency, rate or extent of apoptotic process involved in metanephric collecting duct development.
1900217	regulation of apoptotic process involved in metanephric nephron tubule development	P	Any process that modulates the frequency, rate or extent of apoptotic process involved in metanephric nephron tubule development.
1900218	negative regulation of apoptotic process involved in metanephric nephron tubule development	P	Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic process involved in metanephric nephron tubule development.
1900219	positive regulation of apoptotic process involved in metanephric nephron tubule development	P	Any process that activates or increases the frequency, rate or extent of apoptotic process involved in metanephric nephron tubule development.
1900220	semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis	P	Any semaphorin-plexin signaling pathway that contributes to bone trabecula morphogenesis.
1900221	regulation of beta-amyloid clearance	P	Any process that modulates the frequency, rate or extent of beta-amyloid clearance.
1900222	negative regulation of beta-amyloid clearance	P	Any process that stops, prevents or reduces the frequency, rate or extent of beta-amyloid clearance.
1900223	positive regulation of beta-amyloid clearance	P	Any process that activates or increases the frequency, rate or extent of beta-amyloid clearance.
1900224	positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry	P	Any process that activates or increases the frequency, rate or extent of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry.
1900225	regulation of NLRP3 inflammasome complex assembly	P	Any process that modulates the frequency, rate or extent of NLRP3 inflammasome complex assembly.
1900226	negative regulation of NLRP3 inflammasome complex assembly	P	Any process that stops, prevents or reduces the frequency, rate or extent of NLRP3 inflammasome complex assembly.
1900227	positive regulation of NLRP3 inflammasome complex assembly	P	Any process that activates or increases the frequency, rate or extent of NLRP3 inflammasome complex assembly.
1900228	regulation of single-species biofilm formation in or on host organism	P	Any process that modulates the frequency, rate or extent of single-species biofilm formation in or on host organism.
1900229	negative regulation of single-species biofilm formation in or on host organism	P	Any process that stops, prevents or reduces the frequency, rate or extent of single-species biofilm formation in or on host organism.
1900230	positive regulation of single-species biofilm formation in or on host organism	P	Any process that activates or increases the frequency, rate or extent of single-species biofilm formation in or on host organism.
1900231	regulation of single-species biofilm formation on inanimate substrate	P	Any process that modulates the frequency, rate or extent of single-species biofilm formation on inanimate substrate.
1900232	negative regulation of single-species biofilm formation on inanimate substrate	P	Any process that stops, prevents or reduces the frequency, rate or extent of single-species biofilm formation on inanimate substrate.
1900233	positive regulation of single-species biofilm formation on inanimate substrate	P	Any process that activates or increases the frequency, rate or extent of single-species biofilm formation on inanimate substrate.
1900234	regulation of Kit signaling pathway	P	Any process that modulates the frequency, rate or extent of Kit signaling pathway.
1900235	negative regulation of Kit signaling pathway	P	Any process that stops, prevents or reduces the frequency, rate or extent of Kit signaling pathway.
1900236	positive regulation of Kit signaling pathway	P	Any process that activates or increases the frequency, rate or extent of Kit signaling pathway.
1900237	positive regulation of induction of conjugation with cellular fusion	P	Any process that activates or increases the frequency, rate or extent of induction of conjugation with cellular fusion.
1900238	regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway	P	Any process that modulates the frequency, rate or extent of regulation of metanephric mesenchymal cell migration, by platelet-derived growth factor receptor-beta signaling pathway.
1900239	regulation of phenotypic switching	P	Any process that modulates the frequency, rate or extent of phenotypic switching.
1900240	negative regulation of phenotypic switching	P	Any process that stops, prevents or reduces the frequency, rate or extent of phenotypic switching.
1900241	positive regulation of phenotypic switching	P	Any process that activates or increases the frequency, rate or extent of phenotypic switching.
1900242	regulation of synaptic vesicle endocytosis	P	Any process that modulates the frequency, rate or extent of synaptic vesicle endocytosis.
1900243	negative regulation of synaptic vesicle endocytosis	P	Any process that stops, prevents or reduces the frequency, rate or extent of synaptic vesicle endocytosis.
1900244	positive regulation of synaptic vesicle endocytosis	P	Any process that activates or increases the frequency, rate or extent of synaptic vesicle endocytosis.
1900245	positive regulation of MDA-5 signaling pathway	P	Any process that activates or increases the frequency, rate or extent of MDA-5 signaling pathway.
1900246	positive regulation of RIG-I signaling pathway	P	Any process that activates or increases the frequency, rate or extent of RIG-I signaling pathway.
1900247	regulation of cytoplasmic translational elongation	P	Any process that modulates the frequency, rate or extent of cytoplasmic translational elongation.
1900248	negative regulation of cytoplasmic translational elongation	P	Any process that stops, prevents or reduces the frequency, rate or extent of cytoplasmic translational elongation.
1900249	positive regulation of cytoplasmic translational elongation	P	Any process that activates or increases the frequency, rate or extent of cytoplasmic translational elongation.
1900256	regulation of beta1-adrenergic receptor activity	P	Any process that modulates the frequency, rate or extent of beta1-adrenergic receptor activity.
1900257	negative regulation of beta1-adrenergic receptor activity	P	Any process that stops, prevents or reduces the frequency, rate or extent of beta1-adrenergic receptor activity.
1900258	positive regulation of beta1-adrenergic receptor activity	P	Any process that activates or increases the frequency, rate or extent of beta1-adrenergic receptor activity.
1900259	regulation of RNA-directed 5'-3' RNA polymerase activity	P	Any process that modulates the frequency, rate or extent of RNA-directed 5'-3' RNA polymerase activity.
1900260	negative regulation of RNA-directed 5'-3' RNA polymerase activity	P	Any process that stops, prevents or reduces the frequency, rate or extent of RNA-directed 5'-3' RNA polymerase activity.
1900261	positive regulation of RNA-directed 5'-3' RNA polymerase activity	P	Any process that activates or increases the frequency, rate or extent of RNA-directed 5'-3' RNA polymerase activity.
1900262	regulation of DNA-directed DNA polymerase activity	P	Any process that modulates the frequency, rate or extent of DNA-directed DNA polymerase activity.
1900263	negative regulation of DNA-directed DNA polymerase activity	P	Any process that stops, prevents or reduces the frequency, rate or extent of DNA-directed DNA polymerase activity.
1900264	positive regulation of DNA-directed DNA polymerase activity	P	Any process that activates or increases the frequency, rate or extent of DNA-directed DNA polymerase activity.
1900265	regulation of substance P receptor binding	P	Any process that modulates the frequency, rate or extent of substance P receptor binding.
1900266	negative regulation of substance P receptor binding	P	Any process that stops, prevents or reduces the frequency, rate or extent of substance P receptor binding.
1900267	positive regulation of substance P receptor binding	P	Any process that activates or increases the frequency, rate or extent of substance P receptor binding.
1900268	regulation of reverse transcription	P	Any process that modulates the frequency, rate or extent of reverse transcription.
1900269	negative regulation of reverse transcription	P	Any process that stops, prevents or reduces the frequency, rate or extent of reverse transcription.
1900270	positive regulation of reverse transcription	P	Any process that activates or increases the frequency, rate or extent of reverse transcription.
1900271	regulation of long-term synaptic potentiation	P	Any process that modulates the frequency, rate or extent of long-term synaptic potentiation.
1900272	negative regulation of long-term synaptic potentiation	P	Any process that stops, prevents or reduces the frequency, rate or extent of long-term synaptic potentiation.
1900273	positive regulation of long-term synaptic potentiation	P	Any process that activates or increases the frequency, rate or extent of long-term synaptic potentiation.
1900274	regulation of phospholipase C activity	P	Any process that modulates the frequency, rate or extent of phospholipase C activity.
1900275	negative regulation of phospholipase C activity	P	Any process that stops, prevents or reduces the frequency, rate or extent of phospholipase C activity.
1900276	regulation of proteinase activated receptor activity	P	Any process that modulates the frequency, rate or extent of proteinase activated receptor activity.
1900277	negative regulation of proteinase activated receptor activity	P	Any process that stops, prevents or reduces the frequency, rate or extent of proteinase activated receptor activity.
1900278	positive regulation of proteinase activated receptor activity	P	Any process that activates or increases the frequency, rate or extent of proteinase activated receptor activity.
1900279	regulation of CD4-positive, alpha-beta T cell costimulation	P	Any process that modulates the frequency, rate or extent of CD4-positive, alpha-beta T cell costimulation.
1900280	negative regulation of CD4-positive, alpha-beta T cell costimulation	P	Any process that stops, prevents or reduces the frequency, rate or extent of CD4-positive, alpha-beta T cell costimulation.
1900281	positive regulation of CD4-positive, alpha-beta T cell costimulation	P	Any process that activates or increases the frequency, rate or extent of CD4-positive, alpha-beta T cell costimulation.
1900282	regulation of cellobiose catabolic process	P	Any process that modulates the frequency, rate or extent of cellobiose catabolic process.
1900283	negative regulation of cellobiose catabolic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of cellobiose catabolic process.
1900284	positive regulation of cellobiose catabolic process	P	Any process that activates or increases the frequency, rate or extent of cellobiose catabolic process.
1900285	regulation of cellotriose transport	P	Any process that modulates the frequency, rate or extent of cellotriose transport.
1900286	negative regulation of cellotriose transport	P	Any process that stops, prevents or reduces the frequency, rate or extent of cellotriose transport.
1900287	positive regulation of cellotriose transport	P	Any process that activates or increases the frequency, rate or extent of cellotriose transport.
1900288	regulation of coenzyme F420-dependent bicyclic nitroimidazole catabolic process	P	Any process that modulates the frequency, rate or extent of coenzyme F420-dependent bicyclic nitroimidazole catabolic process.
1900289	negative regulation of coenzyme F420-dependent bicyclic nitroimidazole catabolic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of coenzyme F420-dependent bicyclic nitroimidazole catabolic process.
1900290	positive regulation of coenzyme F420-dependent bicyclic nitroimidazole catabolic process	P	Any process that activates or increases the frequency, rate or extent of coenzyme F420-dependent bicyclic nitroimidazole catabolic process.
1900291	regulation of galactotriose transport	P	Any process that modulates the frequency, rate or extent of galactotriose transport.
1900292	negative regulation of galactotriose transport	P	Any process that stops, prevents or reduces the frequency, rate or extent of galactotriose transport.
1900293	positive regulation of galactotriose transport	P	Any process that activates or increases the frequency, rate or extent of galactotriose transport.
1900294	regulation of heptasaccharide transport	P	Any process that modulates the frequency, rate or extent of heptasaccharide transport.
1900295	negative regulation of heptasaccharide transport	P	Any process that stops, prevents or reduces the frequency, rate or extent of heptasaccharide transport.
1900296	positive regulation of heptasaccharide transport	P	Any process that activates or increases the frequency, rate or extent of heptasaccharide transport.
1900297	regulation of hexasaccharide transport	P	Any process that modulates the frequency, rate or extent of hexasaccharide transport.
1900298	negative regulation of hexasaccharide transport	P	Any process that stops, prevents or reduces the frequency, rate or extent of hexasaccharide transport.
1900299	positive regulation of hexasaccharide transport	P	Any process that activates or increases the frequency, rate or extent of hexasaccharide transport.
1900300	regulation of laminarabiose transport	P	Any process that modulates the frequency, rate or extent of laminarabiose transport.
1900301	negative regulation of laminarabiose transport	P	Any process that stops, prevents or reduces the frequency, rate or extent of laminarabiose transport.
1900302	positive regulation of laminarabiose transport	P	Any process that activates or increases the frequency, rate or extent of laminarabiose transport.
1900303	regulation of laminaritriose transport	P	Any process that modulates the frequency, rate or extent of laminaritriose transport.
1900304	negative regulation of laminaritriose transport	P	Any process that stops, prevents or reduces the frequency, rate or extent of laminaritriose transport.
1900305	positive regulation of laminaritriose transport	P	Any process that activates or increases the frequency, rate or extent of laminaritriose transport.
1900306	regulation of maltoheptaose transport	P	Any process that modulates the frequency, rate or extent of maltoheptaose transport.
1900307	negative regulation of maltoheptaose transport	P	Any process that stops, prevents or reduces the frequency, rate or extent of maltoheptaose transport.
1900308	positive regulation of maltoheptaose transport	P	Any process that activates or increases the frequency, rate or extent of maltoheptaose transport.
1900309	regulation of maltoheptaose metabolic process	P	Any process that modulates the frequency, rate or extent of maltoheptaose metabolic process.
1900310	negative regulation of maltoheptaose metabolic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of maltoheptaose metabolic process.
1900311	positive regulation of maltoheptaose metabolic process	P	Any process that activates or increases the frequency, rate or extent of maltoheptaose metabolic process.
1900312	regulation of maltohexaose transport	P	Any process that modulates the frequency, rate or extent of maltohexaose transport.
1900313	negative regulation of maltohexaose transport	P	Any process that stops, prevents or reduces the frequency, rate or extent of maltohexaose transport.
1900314	positive regulation of maltohexaose transport	P	Any process that activates or increases the frequency, rate or extent of maltohexaose transport.
1900315	regulation of maltopentaose transport	P	Any process that modulates the frequency, rate or extent of maltopentaose transport.
1900316	negative regulation of maltopentaose transport	P	Any process that stops, prevents or reduces the frequency, rate or extent of maltopentaose transport.
1900317	positive regulation of maltopentaose transport	P	Any process that activates or increases the frequency, rate or extent of maltopentaose transport.
1900318	regulation of methane biosynthetic process from dimethylamine	P	Any process that modulates the frequency, rate or extent of methane biosynthetic process from dimethylamine.
1900319	negative regulation of methane biosynthetic process from dimethylamine	P	Any process that stops, prevents or reduces the frequency, rate or extent of methane biosynthetic process from dimethylamine.
1900320	positive regulation of methane biosynthetic process from dimethylamine	P	Any process that activates or increases the frequency, rate or extent of methane biosynthetic process from dimethylamine.
1900321	regulation of maltotetraose transport	P	Any process that modulates the frequency, rate or extent of maltotetraose transport.
1900322	negative regulation of maltotetraose transport	P	Any process that stops, prevents or reduces the frequency, rate or extent of maltotetraose transport.
1900323	positive regulation of maltotetraose transport	P	Any process that activates or increases the frequency, rate or extent of maltotetraose transport.
1900324	regulation of maltotriulose transport	P	Any process that modulates the frequency, rate or extent of maltotriulose transport.
1900325	negative regulation of maltotriulose transport	P	Any process that stops, prevents or reduces the frequency, rate or extent of maltotriulose transport.
1900326	positive regulation of maltotriulose transport	P	Any process that activates or increases the frequency, rate or extent of maltotriulose transport.
1900327	regulation of mannotriose transport	P	Any process that modulates the frequency, rate or extent of mannotriose transport.
1900328	negative regulation of mannotriose transport	P	Any process that stops, prevents or reduces the frequency, rate or extent of mannotriose transport.
1900329	positive regulation of mannotriose transport	P	Any process that activates or increases the frequency, rate or extent of mannotriose transport.
1900330	regulation of methane biosynthetic process from trimethylamine	P	Any process that modulates the frequency, rate or extent of methane biosynthetic process from trimethylamine.
1900331	negative regulation of methane biosynthetic process from trimethylamine	P	Any process that stops, prevents or reduces the frequency, rate or extent of methane biosynthetic process from trimethylamine.
1900332	positive regulation of methane biosynthetic process from trimethylamine	P	Any process that activates or increases the frequency, rate or extent of methane biosynthetic process from trimethylamine.
1900333	regulation of methane biosynthetic process from 3-(methylthio)propionic acid	P	Any process that modulates the frequency, rate or extent of methane biosynthetic process from 3-(methylthio)propionic acid.
1900334	negative regulation of methane biosynthetic process from 3-(methylthio)propionic acid	P	Any process that stops, prevents or reduces the frequency, rate or extent of methane biosynthetic process from 3-(methylthio)propionic acid.
1900335	positive regulation of methane biosynthetic process from 3-(methylthio)propionic acid	P	Any process that activates or increases the frequency, rate or extent of methane biosynthetic process from 3-(methylthio)propionic acid.
1900336	regulation of methane biosynthetic process from carbon monoxide	P	Any process that modulates the frequency, rate or extent of methane biosynthetic process from carbon monoxide.
1900337	negative regulation of methane biosynthetic process from carbon monoxide	P	Any process that stops, prevents or reduces the frequency, rate or extent of methane biosynthetic process from carbon monoxide.
1900338	positive regulation of methane biosynthetic process from carbon monoxide	P	Any process that activates or increases the frequency, rate or extent of methane biosynthetic process from carbon monoxide.
1900339	regulation of methane biosynthetic process from formic acid	P	Any process that modulates the frequency, rate or extent of methane biosynthetic process from formic acid.
1900340	negative regulation of methane biosynthetic process from formic acid	P	Any process that stops, prevents or reduces the frequency, rate or extent of methane biosynthetic process from formic acid.
1900341	positive regulation of methane biosynthetic process from formic acid	P	Any process that activates or increases the frequency, rate or extent of methane biosynthetic process from formic acid.
1900342	regulation of methane biosynthetic process from dimethyl sulfide	P	Any process that modulates the frequency, rate or extent of methane biosynthetic process from dimethyl sulfide.
1900343	negative regulation of methane biosynthetic process from dimethyl sulfide	P	Any process that stops, prevents or reduces the frequency, rate or extent of methane biosynthetic process from dimethyl sulfide.
1900344	positive regulation of methane biosynthetic process from dimethyl sulfide	P	Any process that activates or increases the frequency, rate or extent of methane biosynthetic process from dimethyl sulfide.
1900345	regulation of methane biosynthetic process from methanethiol	P	Any process that modulates the frequency, rate or extent of methane biosynthetic process from methanethiol.
1900346	negative regulation of methane biosynthetic process from methanethiol	P	Any process that stops, prevents or reduces the frequency, rate or extent of methane biosynthetic process from methanethiol.
1900347	positive regulation of methane biosynthetic process from methanethiol	P	Any process that activates or increases the frequency, rate or extent of methane biosynthetic process from methanethiol.
1900348	regulation of methane biosynthetic process from methylamine	P	Any process that modulates the frequency, rate or extent of methane biosynthetic process from methylamine.
1900349	negative regulation of methane biosynthetic process from methylamine	P	Any process that stops, prevents or reduces the frequency, rate or extent of methane biosynthetic process from methylamine.
1900350	positive regulation of methane biosynthetic process from methylamine	P	Any process that activates or increases the frequency, rate or extent of methane biosynthetic process from methylamine.
1900351	regulation of methanofuran biosynthetic process	P	Any process that modulates the frequency, rate or extent of methanofuran biosynthetic process.
1900352	negative regulation of methanofuran biosynthetic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of methanofuran biosynthetic process.
1900353	positive regulation of methanofuran biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of methanofuran biosynthetic process.
1900354	regulation of methanofuran metabolic process	P	Any process that modulates the frequency, rate or extent of methanofuran metabolic process.
1900355	negative regulation of methanofuran metabolic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of methanofuran metabolic process.
1900356	positive regulation of methanofuran metabolic process	P	Any process that activates or increases the frequency, rate or extent of methanofuran metabolic process.
1900357	regulation of nigerotriose transport	P	Any process that modulates the frequency, rate or extent of nigerotriose transport.
1900358	negative regulation of nigerotriose transport	P	Any process that stops, prevents or reduces the frequency, rate or extent of nigerotriose transport.
1900359	positive regulation of nigerotriose transport	P	Any process that activates or increases the frequency, rate or extent of nigerotriose transport.
1900360	regulation of pentasaccharide transport	P	Any process that modulates the frequency, rate or extent of pentasaccharide transport.
1900361	negative regulation of pentasaccharide transport	P	Any process that stops, prevents or reduces the frequency, rate or extent of pentasaccharide transport.
1900362	positive regulation of pentasaccharide transport	P	Any process that activates or increases the frequency, rate or extent of pentasaccharide transport.
1900363	regulation of mRNA polyadenylation	P	Any process that modulates the frequency, rate or extent of mRNA polyadenylation.
1900364	negative regulation of mRNA polyadenylation	P	Any process that stops, prevents or reduces the frequency, rate or extent of mRNA polyadenylation.
1900365	positive regulation of mRNA polyadenylation	P	Any process that activates or increases the frequency, rate or extent of mRNA polyadenylation.
1900366	negative regulation of defense response to insect	P	Any process that stops, prevents or reduces the frequency, rate or extent of defense response to insect.
1900367	positive regulation of defense response to insect	P	Any process that activates or increases the frequency, rate or extent of defense response to insect.
1900368	regulation of RNA interference	P	Any process that modulates the frequency, rate or extent of RNA interference.
1900369	negative regulation of RNA interference	P	Any process that stops, prevents or reduces the frequency, rate or extent of RNA interference.
1900370	positive regulation of RNA interference	P	Any process that activates or increases the frequency, rate or extent of RNA interference.
1900371	regulation of purine nucleotide biosynthetic process	P	Any process that modulates the frequency, rate or extent of purine nucleotide biosynthetic processes.
1900372	negative regulation of purine nucleotide biosynthetic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of purine nucleotide biosynthetic processes.
1900373	positive regulation of purine nucleotide biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of purine nucleotide biosynthetic processes.
1900374	positive regulation of mating type switching by regulation of transcription from RNA polymerase II promoter	P	A regulation of transcription from RNA polymerase II promoter that results in positive regulation of mating type switching.
1900375	positive regulation of inositol biosynthetic process by positive regulation of transcription from RNA polymerase II promoter	P	A positive regulation of transcription from RNA polymerase II promoter that results in positive regulation of inositol biosynthetic process.
1900376	regulation of secondary metabolite biosynthetic process	P	Any process that modulates the frequency, rate or extent of secondary metabolite biosynthetic process.
1900377	negative regulation of secondary metabolite biosynthetic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of secondary metabolite biosynthetic process.
1900378	positive regulation of secondary metabolite biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of secondary metabolite biosynthetic process.
1900379	regulation of asperthecin biosynthetic process	P	Any process that modulates the frequency, rate or extent of asperthecin biosynthetic process.
1900380	negative regulation of asperthecin biosynthetic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of asperthecin biosynthetic process.
1900381	positive regulation of asperthecin biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of asperthecin biosynthetic process.
1900382	regulation of thiamine biosynthetic process by regulation of transcription from RNA polymerase II promoter	P	A regulation of transcription from RNA polymerase II promoter that results in regulation of thiamine biosynthetic process.
1900383	regulation of synaptic plasticity by receptor localization to synapse	P	Any process that modulates synaptic plasticity, the ability of synapses to change as circumstances require, via receptor localization to the synapse, the junction between a nerve fiber of one neuron and another neuron or muscle fiber or glial cell. Processes may include receptor transport to, and/or maintenance at, the synapse.
1900384	regulation of flavonol biosynthetic process	P	Any process that modulates the frequency, rate or extent of flavonol biosynthetic process.
1900385	negative regulation of flavonol biosynthetic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of flavonol biosynthetic process.
1900386	positive regulation of flavonol biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of flavonol biosynthetic process.
1900387	negative regulation of cell-cell adhesion by negative regulation of transcription from RNA polymerase II promoter	P	A negative regulation of transcription from RNA polymerase II promoter that results in negative regulation of cell-cell adhesion.
1900389	regulation of glucose import by regulation of transcription from RNA polymerase II promoter	P	A regulation of transcription from RNA polymerase II promoter that results in regulation of glucose import.
1900390	regulation of iron ion import	P	Any process that modulates the frequency, rate or extent of iron ion import.
1900391	regulation of cAMP-mediated signaling by regulation of transcription from RNA polymerase II promoter	P	A regulation of transcription from RNA polymerase II promoter that results in regulation of cAMP-mediated signaling.
1900392	regulation of transport by negative regulation of transcription from RNA polymerase II promoter	P	A negative regulation of transcription from RNA polymerase II promoter that results in regulation of transport.
1900393	regulation of iron ion transport by regulation of transcription from RNA polymerase II promoter	P	A regulation of transcription from RNA polymerase II promoter that results in regulation of iron ion transport.
1900394	regulation of kojic acid biosynthetic process	P	Any process that modulates the frequency, rate or extent of kojic acid biosynthetic process.
1900395	negative regulation of kojic acid biosynthetic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of kojic acid biosynthetic process.
1900396	positive regulation of kojic acid biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of kojic acid biosynthetic process.
1900397	regulation of pyrimidine nucleotide biosynthetic process	P	Any process that modulates the frequency, rate or extent of pyrimidine nucleotide biosynthetic process.
1900398	negative regulation of pyrimidine nucleotide biosynthetic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of pyrimidine nucleotide biosynthetic process.
1900399	positive regulation of pyrimidine nucleotide biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of pyrimidine nucleotide biosynthetic process.
1900400	regulation of iron ion import by regulation of transcription from RNA polymerase II promoter	P	A regulation of transcription from RNA polymerase II promoter that results in regulation of iron ion import.
1900401	regulation of meiosis by regulation of transcription from RNA polymerase II promoter	P	A regulation of transcription from RNA polymerase II promoter that results in regulation of meiosis.
1900402	regulation of carbohydrate metabolic process by regulation of transcription from RNA polymerase II promoter	P	A regulation of transcription from RNA polymerase II promoter that results in regulation of carbohydrate metabolic process.
1900403	negative regulation of cellular amino acid biosynthetic process by negative regulation of transcription from RNA polymerase II promoter	P	A negative regulation of transcription from RNA polymerase II promoter that results in negative regulation of cellular amino acid biosynthetic process.
1900404	positive regulation of DNA repair by positive regulation of transcription from RNA polymerase II promoter	P	A positive regulation of transcription from RNA polymerase II promoter that results in positive regulation of DNA repair.
1900405	regulation of cell separation after cytokinesis by regulation of transcription from RNA polymerase II promoter	P	A regulation of transcription from RNA polymerase II promoter that results in regulation of cell separation after cytokinesis.
1900406	regulation of conjugation with cellular fusion by regulation of transcription from RNA polymerase II promoter	P	A regulation of transcription from RNA polymerase II promoter that results in regulation of conjugation with cellular fusion.
1900407	regulation of cellular response to oxidative stress	P	Any process that modulates the frequency, rate or extent of cellular response to oxidative stress.
1900408	negative regulation of cellular response to oxidative stress	P	Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to oxidative stress.
1900409	positive regulation of cellular response to oxidative stress	P	Any process that activates or increases the frequency, rate or extent of cellular response to oxidative stress.
1900413	positive regulation of phospholipid biosynthetic process by positive regulation of transcription from RNA polymerase II promoter	P	A positive regulation of transcription from RNA polymerase II promoter that results in positive regulation of phospholipid biosynthetic process.
1900414	regulation of cytokinesis by regulation of transcription from RNA polymerase II promoter	P	A regulation of transcription from RNA polymerase II promoter that results in regulation of cytokinesis.
1900415	regulation of fungal-type cell wall biogenesis by regulation of transcription from RNA polymerase II promoter	P	A regulation of transcription from RNA polymerase II promoter that results in regulation of fungal-type cell wall biogenesis.
1900416	regulation of 4,6-pyruvylated galactose residue biosynthetic process by regulation of transcription from RNA polymerase II promoter	P	A regulation of transcription from RNA polymerase II promoter that results in regulation of 4,6-pyruvylated galactose residue biosynthetic process.
1900417	negative regulation of transmembrane transport by negative regulation of transcription from RNA polymerase II promoter	P	A negative regulation of transcription from RNA polymerase II promoter that results in negative regulation of transmembrane transport.
1900418	positive regulation of purine nucleotide biosynthetic process by positive regulation of transcription from RNA polymerase II promoter	P	A positive regulation of transcription from RNA polymerase II promoter that results in positive regulation of purine nucleotide biosynthetic process.
1900419	regulation of cellular alcohol catabolic process	P	Any process that modulates the frequency, rate or extent of cellular alcohol catabolic process.
1900420	negative regulation of cellular alcohol catabolic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of cellular alcohol catabolic process.
1900421	positive regulation of cellular alcohol catabolic process	P	Any process that activates or increases the frequency, rate or extent of cellular alcohol catabolic process.
1900422	positive regulation of cellular alcohol catabolic process by positive regulation of transcription from RNA polymerase II promoter	P	A positive regulation of transcription from RNA polymerase II promoter that results in positive regulation of cellular alcohol catabolic process.
1900423	positive regulation of mating type switching by positive regulation of transcription from RNA polymerase II promoter	P	A positive regulation of transcription from RNA polymerase II promoter that results in positive regulation of mating type switching.
1900424	regulation of defense response to bacterium	P	Any process that modulates the frequency, rate or extent of defense response to bacterium.
1900425	negative regulation of defense response to bacterium	P	Any process that stops, prevents or reduces the frequency, rate or extent of defense response to bacterium.
1900426	positive regulation of defense response to bacterium	P	Any process that activates or increases the frequency, rate or extent of defense response to bacterium.
1900427	regulation of cellular response to oxidative stress by regulation of transcription from RNA polymerase II promoter	P	A regulation of transcription from RNA polymerase II promoter that results in regulation of cellular response to oxidative stress.
1900428	regulation of filamentous growth of a population of unicellular organisms	P	Any process that modulates the frequency, rate or extent of filamentous growth of a population of unicellular organisms.
1900429	negative regulation of filamentous growth of a population of unicellular organisms	P	Any process that stops, prevents or reduces the frequency, rate or extent of filamentous growth of a population of unicellular organisms.
1900430	positive regulation of filamentous growth of a population of unicellular organisms	P	Any process that activates or increases the frequency, rate or extent of filamentous growth of a population of unicellular organisms.
1900431	regulation of filamentous growth of a population of unicellular organisms in response to heat	P	Any process that modulates the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to heat.
1900432	negative regulation of filamentous growth of a population of unicellular organisms in response to heat	P	Any process that stops, prevents or reduces the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to heat.
1900433	positive regulation of filamentous growth of a population of unicellular organisms in response to heat	P	Any process that activates or increases the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to heat.
1900434	regulation of filamentous growth of a population of unicellular organisms in response to starvation	P	Any process that modulates the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to starvation.
1900435	negative regulation of filamentous growth of a population of unicellular organisms in response to starvation	P	Any process that stops, prevents or reduces the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to starvation.
1900436	positive regulation of filamentous growth of a population of unicellular organisms in response to starvation	P	Any process that activates or increases the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to starvation.
1900437	regulation of filamentous growth of a population of unicellular organisms in response to chemical stimulus	P	Any process that modulates the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to chemical stimulus.
1900438	negative regulation of filamentous growth of a population of unicellular organisms in response to chemical stimulus	P	Any process that stops, prevents or reduces the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to chemical stimulus.
1900439	positive regulation of filamentous growth of a population of unicellular organisms in response to chemical stimulus	P	Any process that activates or increases the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to chemical stimulus.
1900440	regulation of filamentous growth of a population of unicellular organisms in response to neutral pH	P	Any process that modulates the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to neutral pH.
1900441	negative regulation of filamentous growth of a population of unicellular organisms in response to neutral pH	P	Any process that stops, prevents or reduces the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to neutral pH.
1900442	positive regulation of filamentous growth of a population of unicellular organisms in response to neutral pH	P	Any process that activates or increases the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to neutral pH.
1900443	regulation of filamentous growth of a population of unicellular organisms in response to biotic stimulus	P	Any process that modulates the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to biotic stimulus.
1900444	negative regulation of filamentous growth of a population of unicellular organisms in response to biotic stimulus	P	Any process that stops, prevents or reduces the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to biotic stimulus.
1900445	positive regulation of filamentous growth of a population of unicellular organisms in response to biotic stimulus	P	Any process that activates or increases the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to biotic stimulus.
1900446	negative regulation of tRNA transcription from RNA polymerase III promoter	P	Any process that stops, prevents or reduces the frequency, rate or extent of tRNA transcription from RNA polymerase III promoter.
1900447	regulation of cell morphogenesis involved in phenotypic switching	P	Any process that modulates the frequency, rate or extent of cell morphogenesis contributing a phenotypic switch. Cell morphogenesis involved in differentiation is the change in form (cell shape and size) that occurs when relatively unspecialized cells, such as the opaque cells of C. albicans, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history.
1900448	regulation of pyrimidine nucleotide biosynthetic process by positive regulation of transcription from RNA polymerase II promoter	P	Any process that modulates the frequency, rate or extent of pyrimidine nucleotide biosynthesis by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter.
1900449	regulation of glutamate receptor signaling pathway	P	Any process that modulates the frequency, rate or extent of glutamate receptor signaling pathway.
1900450	negative regulation of glutamate receptor signaling pathway	P	Any process that stops, prevents or reduces the frequency, rate or extent of glutamate receptor signaling pathway.
1900451	positive regulation of glutamate receptor signaling pathway	P	Any process that activates or increases the frequency, rate or extent of glutamate receptor signaling pathway.
1900452	regulation of long term synaptic depression	P	Any process that modulates the frequency, rate or extent of long term synaptic depression.
1900453	negative regulation of long term synaptic depression	P	Any process that stops, prevents or reduces the frequency, rate or extent of long term synaptic depression.
1900454	positive regulation of long term synaptic depression	P	Any process that activates or increases the frequency, rate or extent of long term synaptic depression.
1900455	regulation of flocculation via cell wall protein-carbohydrate interaction	P	Any process that modulates the frequency, rate or extent of flocculation via cell wall protein-carbohydrate interaction.
1900457	regulation of brassinosteroid mediated signaling pathway	P	Any process that modulates the frequency, rate or extent of brassinosteroid mediated signaling pathway.
1900458	negative regulation of brassinosteroid mediated signaling pathway	P	Any process that stops, prevents or reduces the frequency, rate or extent of brassinosteroid mediated signaling pathway.
1900459	positive regulation of brassinosteroid mediated signaling pathway	P	Any process that activates or increases the frequency, rate or extent of brassinosteroid mediated signaling pathway.
1900460	negative regulation of invasive growth in response to glucose limitation by negative regulation of transcription from RNA polymerase II promoter	P	Any process that stops, prevents, or reduces the frequency, rate or extent of invasive growth in response to glucose limitation by stopping, preventing, or reducing the frequency, rate or extent of transcription from an RNA polymerase II promoter.
1900461	positive regulation of pseudohyphal growth by positive regulation of transcription from RNA polymerase II promoter	P	Any process that activates or increases the frequency, rate or extent of pseudohyphal growth by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter.
1900462	negative regulation of pseudohyphal growth by negative regulation of transcription from RNA polymerase II promoter	P	Any process that activates or increases the frequency, rate or extent of pseudohyphal growth by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II Any process that stops, prevents, or reduces the frequency, rate or extent of pseudohyphal growth by stopping, preventing, or reducing the frequency, rate or extent of transcription from an RNA polymerase II promoter.
1900463	negative regulation of cellular response to alkaline pH by negative regulation of transcription from RNA polymerase II promoter	P	Any process that stops, prevents, or reduces the frequency, rate or extent of cellular response to alkalinity by stopping, preventing, or reducing the frequency, rate or extent of transcription from an RNA polymerase II promoter.
1900464	negative regulation of cellular hyperosmotic salinity response by negative regulation of transcription from RNA polymerase II promoter	P	Any process that stops, prevents, or reduces the frequency, rate or extent of cellular hyperosmotic salinity response by stopping, preventing, or reducing the frequency, rate or extent of transcription from an RNA polymerase II promoter.
1900465	negative regulation of arginine catabolic process by negative regulation of transcription from RNA polymerase II promoter	P	Any process that stops, prevents, or reduces the frequency, rate or extent of cellular arginine catabolic process by stopping, preventing, or reducing the frequency, rate or extent of transcription from an RNA polymerase II promoter.
1900466	positive regulation of arginine biosynthetic process by positive regulation of transcription from RNA polymerase II promoter	P	Any process that activates or increases the frequency, rate or extent of arginine biosynthetic process by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter.
1900468	regulation of phosphatidylserine biosynthetic process	P	Any process that modulates the frequency, rate or extent of phosphatidylserine biosynthetic process.
1900469	negative regulation of phosphatidylserine biosynthetic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of phosphatidylserine biosynthetic process.
1900470	positive regulation of phosphatidylserine biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of phosphatidylserine biosynthetic process.
1900471	negative regulation of inositol biosynthetic process by negative regulation of transcription from RNA polymerase II promoter	P	Any process that stops, prevents, or reduces the frequency, rate or extent of inositol biosynthetic process by stopping, preventing, or reducing the frequency, rate or extent of transcription from an RNA polymerase II promoter.
1900472	positive regulation of phosphatidylcholine biosynthetic process by positive regulation of transcription from RNA polymerase II promoter	P	Any process that activates or increases the frequency, rate or extent of phosphatidylcholine biosynthetic process by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter.
1900473	negative regulation of phosphatidylcholine biosynthetic process by negative regulation of transcription from RNA polymerase II promoter	P	Any process that stops, prevents, or reduces the frequency, rate or extent of phosphatidylcholine biosynthetic process by stopping, preventing, or reducing the frequency, rate or extent of transcription from an RNA polymerase II promoter.
1900474	negative regulation of mating type switching by negative regulation of transcription from RNA polymerase II promoter	P	Any process that stops, prevents, or reduces the frequency, rate or extent of mating type switching by stopping, preventing, or reducing the frequency, rate or extent of transcription from an RNA polymerase II promoter.
1900475	positive regulation of meiosis by negative regulation of transcription from RNA polymerase II promoter	P	Any process that activates or increases the frequency, rate or extent of meiosis by stopping, preventing, or reducing the frequency, rate or extent of transcription from an RNA polymerase II promoter.
1900476	positive regulation of meiosis by positive regulation of transcription from RNA polymerase II promoter	P	Any process that activates or increases the frequency, rate or extent of meiosis by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter.
1900477	negative regulation of G1/S transition of mitotic cell cycle by negative regulation of transcription from RNA polymerase II promoter	P	Any process that stops, prevents, or reduces the frequency, rate or extent of G1/S transition of mitotic cell cycle by stopping, preventing, or reducing the frequency, rate or extent of transcription from an RNA polymerase II promoter.
1900478	positive regulation of sulfate assimilation by positive regulation of transcription from RNA polymerase II promoter	P	Any process that activates or increases the frequency, rate or extent of sulfate assimilation by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter.
1900479	positive regulation of flocculation via cell wall protein-carbohydrate interaction	P	Any process that activates or increases the frequency, rate or extent of flocculation via cell wall protein-carbohydrate interaction.
1900480	regulation of diacylglycerol biosynthetic process	P	Any process that modulates the frequency, rate or extent of diacylglycerol biosynthetic process.
1900481	negative regulation of diacylglycerol biosynthetic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of diacylglycerol biosynthetic process.
1900482	positive regulation of diacylglycerol biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of diacylglycerol biosynthetic process.
1900483	regulation of protein targeting to vacuolar membrane	P	Any process that modulates the frequency, rate or extent of protein targeting to vacuolar membrane.
1900484	negative regulation of protein targeting to vacuolar membrane	P	Any process that stops, prevents or reduces the frequency, rate or extent of protein targeting to vacuolar membrane.
1900485	positive regulation of protein targeting to vacuolar membrane	P	Any process that activates or increases the frequency, rate or extent of protein targeting to vacuolar membrane.
1900486	positive regulation of isopentenyl diphosphate biosynthetic process, mevalonate pathway	P	Any process that activates or increases the frequency, rate or extent of isopentenyl diphosphate biosynthetic process, mevalonate pathway.
1900487	regulation of [2Fe-2S] cluster assembly	P	Any process that modulates the frequency, rate or extent of [2Fe-2S] cluster assembly.
1900488	negative regulation of [2Fe-2S] cluster assembly	P	Any process that stops, prevents or reduces the frequency, rate or extent of [2Fe-2S] cluster assembly.
1900489	positive regulation of [2Fe-2S] cluster assembly	P	Any process that activates or increases the frequency, rate or extent of [2Fe-2S] cluster assembly.
1900490	positive regulation of hydroxymethylglutaryl-CoA reductase (NADPH) activity	P	Any process that activates or increases the frequency, rate or extent of hydroxymethylglutaryl-CoA reductase (NADPH) activity.
1900491	regulation of [4Fe-4S] cluster assembly	P	Any process that modulates the frequency, rate or extent of [4Fe-4S] cluster assembly.
1900492	negative regulation of [4Fe-4S] cluster assembly	P	Any process that stops, prevents or reduces the frequency, rate or extent of [4Fe-4S] cluster assembly.
1900493	positive regulation of [4Fe-4S] cluster assembly	P	Any process that activates or increases the frequency, rate or extent of [4Fe-4S] cluster assembly.
1900494	regulation of butyryl-CoA biosynthetic process from acetyl-CoA	P	Any process that modulates the frequency, rate or extent of butyryl-CoA biosynthetic process from acetyl-CoA.
1900495	negative regulation of butyryl-CoA biosynthetic process from acetyl-CoA	P	Any process that stops, prevents or reduces the frequency, rate or extent of butyryl-CoA biosynthetic process from acetyl-CoA.
1900496	positive regulation of butyryl-CoA biosynthetic process from acetyl-CoA	P	Any process that activates or increases the frequency, rate or extent of butyryl-CoA biosynthetic process from acetyl-CoA.
1900497	regulation of butyryl-CoA catabolic process to butanol	P	Any process that modulates the frequency, rate or extent of butyryl-CoA catabolic process to butanol.
1900498	negative regulation of butyryl-CoA catabolic process to butanol	P	Any process that stops, prevents or reduces the frequency, rate or extent of butyryl-CoA catabolic process to butanol.
1900499	positive regulation of butyryl-CoA catabolic process to butanol	P	Any process that activates or increases the frequency, rate or extent of butyryl-CoA catabolic process to butanol.
1900500	regulation of butyryl-CoA catabolic process to butyrate	P	Any process that modulates the frequency, rate or extent of butyryl-CoA catabolic process to butyrate.
1900501	negative regulation of butyryl-CoA catabolic process to butyrate	P	Any process that stops, prevents or reduces the frequency, rate or extent of butyryl-CoA catabolic process to butyrate.
1900502	positive regulation of butyryl-CoA catabolic process to butyrate	P	Any process that activates or increases the frequency, rate or extent of butyryl-CoA catabolic process to butyrate.
1900503	regulation of cellulosome assembly	P	Any process that modulates the frequency, rate or extent of cellulosome assembly.
1900504	negative regulation of cellulosome assembly	P	Any process that stops, prevents or reduces the frequency, rate or extent of cellulosome assembly.
1900505	positive regulation of cellulosome assembly	P	Any process that activates or increases the frequency, rate or extent of cellulosome assembly.
1900506	regulation of iron-sulfur-molybdenum cofactor assembly	P	Any process that modulates the frequency, rate or extent of iron-sulfur-molybdenum cofactor assembly.
1900507	negative regulation of iron-sulfur-molybdenum cofactor assembly	P	Any process that stops, prevents or reduces the frequency, rate or extent of iron-sulfur-molybdenum cofactor assembly.
1900508	positive regulation of iron-sulfur-molybdenum cofactor assembly	P	Any process that activates or increases the frequency, rate or extent of iron-sulfur-molybdenum cofactor assembly.
1900509	regulation of pentose catabolic process to ethanol	P	Any process that modulates the frequency, rate or extent of pentose catabolic process to ethanol.
1900510	negative regulation of pentose catabolic process to ethanol	P	Any process that stops, prevents or reduces the frequency, rate or extent of pentose catabolic process to ethanol.
1900511	positive regulation of pentose catabolic process to ethanol	P	Any process that activates or increases the frequency, rate or extent of pentose catabolic process to ethanol.
1900512	regulation of starch utilization system complex assembly	P	Any process that modulates the frequency, rate or extent of starch utilization system complex assembly.
1900513	negative regulation of starch utilization system complex assembly	P	Any process that stops, prevents or reduces the frequency, rate or extent of starch utilization system complex assembly.
1900514	positive regulation of starch utilization system complex assembly	P	Any process that activates or increases the frequency, rate or extent of starch utilization system complex assembly.
1900515	regulation of xylose catabolic process to ethanol	P	Any process that modulates the frequency, rate or extent of xylose catabolic process to ethanol.
1900516	negative regulation of xylose catabolic process to ethanol	P	Any process that stops, prevents or reduces the frequency, rate or extent of xylose catabolic process to ethanol.
1900517	positive regulation of xylose catabolic process to ethanol	P	Any process that activates or increases the frequency, rate or extent of xylose catabolic process to ethanol.
1900518	regulation of response to pullulan	P	Any process that modulates the frequency, rate or extent of response to pullulan.
1900519	negative regulation of response to pullulan	P	Any process that stops, prevents or reduces the frequency, rate or extent of response to pullulan.
1900520	positive regulation of response to pullulan	P	Any process that activates or increases the frequency, rate or extent of response to pullulan.
1900521	regulation of response to amylopectin	P	Any process that modulates the frequency, rate or extent of response to amylopectin.
1900522	negative regulation of response to amylopectin	P	Any process that stops, prevents or reduces the frequency, rate or extent of response to amylopectin.
1900523	positive regulation of response to amylopectin	P	Any process that activates or increases the frequency, rate or extent of response to amylopectin.
1900524	positive regulation of flocculation via cell wall protein-carbohydrate interaction by positive regulation of transcription from RNA polymerase II promoter	P	Any process that activates or increases the frequency, rate or extent of flocculation via cell wall protein-carbohydrate interaction process by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter.
1900525	positive regulation of phosphatidylserine biosynthetic process by positive regulation of transcription from RNA polymerase II promoter	P	Any process that activates or increases the frequency, rate or extent of phosphatidylserine biosynthetic process by activating or increasing the frequency, rate or extent of transcription from an RNA polymerase II promoter.
1900526	negative regulation of phosphatidylserine biosynthetic process by negative regulation of transcription from RNA polymerase II promoter	P	Any process that stops, prevents, or reduces the frequency, rate or extent of phosphatidylserine biosynthetic process by stopping, preventing, or reducing the frequency, rate or extent of transcription from an RNA polymerase II promoter.
1900533	palmitic acid metabolic process	P	The chemical reactions and pathways involving palmitic acid.
1900534	palmitic acid catabolic process	P	The chemical reactions and pathways resulting in the breakdown of palmitic acid.
1900535	palmitic acid biosynthetic process	P	The chemical reactions and pathways resulting in the formation of palmitic acid.
1900539	fumonisin metabolic process	P	The chemical reactions and pathways involving fumonisin.
1900540	fumonisin catabolic process	P	The chemical reactions and pathways resulting in the breakdown of fumonisin.
1900541	fumonisin biosynthetic process	P	The chemical reactions and pathways resulting in the formation of fumonisin.
1900542	regulation of purine nucleotide metabolic process	P	Any process that modulates the frequency, rate or extent of purine nucleotide metabolic process.
1900543	negative regulation of purine nucleotide metabolic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of purine nucleotide metabolic process.
1900544	positive regulation of purine nucleotide metabolic process	P	Any process that activates or increases the frequency, rate or extent of purine nucleotide metabolic process.
1900545	regulation of phenotypic switching by regulation of transcription from RNA polymerase II promoter	P	A regulation of transcription from RNA polymerase II promoter that results in regulation of phenotypic switching.
1900546	positive regulation of phenotypic switching by regulation of transcription from RNA polymerase II promoter	P	A regulation of transcription from RNA polymerase II promoter that results in positive regulation of phenotypic switching.
1900547	negative regulation of phenotypic switching by regulation of transcription from RNA polymerase II promoter	P	A regulation of transcription from RNA polymerase II promoter that results in negative regulation of phenotypic switching.
1900548	heme b catabolic process	P	The chemical reactions and pathways resulting in the breakdown of heme b, a Fe(II) porphyrin complex readily isolated from the hemoglobin of beef blood, but also found in other proteins including other hemoglobins, myoglobins, cytochromes P-450, catalases, peroxidases as well as b type cytochromes.
1900549	N',N'',N'''-triacetylfusarinine C metabolic process	P	The chemical reactions and pathways involving N',N'',N'''-triacetylfusarinine C.
1900550	N',N'',N'''-triacetylfusarinine C catabolic process	P	The chemical reactions and pathways resulting in the breakdown of N',N'',N'''-triacetylfusarinine C.
1900551	N',N'',N'''-triacetylfusarinine C biosynthetic process	P	The chemical reactions and pathways resulting in the formation of N',N'',N'''-triacetylfusarinine C.
1900552	asperfuranone metabolic process	P	The chemical reactions and pathways involving asperfuranone.
1900553	asperfuranone catabolic process	P	The chemical reactions and pathways resulting in the breakdown of asperfuranone.
1900554	asperfuranone biosynthetic process	P	The chemical reactions and pathways resulting in the formation of asperfuranone.
1900555	emericellamide metabolic process	P	The chemical reactions and pathways involving emericellamide.
1900556	emericellamide catabolic process	P	The chemical reactions and pathways resulting in the breakdown of emericellamide.
1900557	emericellamide biosynthetic process	P	The chemical reactions and pathways resulting in the formation of emericellamide.
1900558	austinol metabolic process	P	The chemical reactions and pathways involving austinol.
1900559	austinol catabolic process	P	The chemical reactions and pathways resulting in the breakdown of austinol.
1900560	austinol biosynthetic process	P	The chemical reactions and pathways resulting in the formation of austinol.
1900561	dehydroaustinol metabolic process	P	The chemical reactions and pathways involving dehydroaustinol.
1900562	dehydroaustinol catabolic process	P	The chemical reactions and pathways resulting in the breakdown of dehydroaustinol.
1900563	dehydroaustinol biosynthetic process	P	The chemical reactions and pathways resulting in the formation of dehydroaustinol.
1900564	chanoclavine-I metabolic process	P	The chemical reactions and pathways involving chanoclavine-I.
1900565	chanoclavine-I catabolic process	P	The chemical reactions and pathways resulting in the breakdown of chanoclavine-I.
1900566	chanoclavine-I biosynthetic process	P	The chemical reactions and pathways resulting in the formation of chanoclavine-I.
1900567	chanoclavine-I aldehyde metabolic process	P	The chemical reactions and pathways involving chanoclavine-I aldehyde.
1900568	chanoclavine-I aldehyde catabolic process	P	The chemical reactions and pathways resulting in the breakdown of chanoclavine-I aldehyde.
1900569	chanoclavine-I aldehyde biosynthetic process	P	The chemical reactions and pathways resulting in the formation of chanoclavine-I aldehyde.
1900570	diorcinol metabolic process	P	The chemical reactions and pathways involving diorcinol.
1900571	diorcinol catabolic process	P	The chemical reactions and pathways resulting in the breakdown of diorcinol.
1900572	diorcinol biosynthetic process	P	The chemical reactions and pathways resulting in the formation of diorcinol.
1900573	emodin metabolic process	P	The chemical reactions and pathways involving emodin.
1900574	emodin catabolic process	P	The chemical reactions and pathways resulting in the breakdown of emodin.
1900575	emodin biosynthetic process	P	The chemical reactions and pathways resulting in the formation of emodin.
1900576	gerfelin metabolic process	P	The chemical reactions and pathways involving gerfelin.
1900577	gerfelin catabolic process	P	The chemical reactions and pathways resulting in the breakdown of gerfelin.
1900578	gerfelin biosynthetic process	P	The chemical reactions and pathways resulting in the formation of gerfelin.
1900579	(17Z)-protosta-17(20),24-dien-3beta-ol metabolic process	P	The chemical reactions and pathways involving (17Z)-protosta-17(20),24-dien-3beta-ol.
1900580	(17Z)-protosta-17(20),24-dien-3beta-ol catabolic process	P	The chemical reactions and pathways resulting in the breakdown of (17Z)-protosta-17(20),24-dien-3beta-ol.
1900581	(17Z)-protosta-17(20),24-dien-3beta-ol biosynthetic process	P	The chemical reactions and pathways resulting in the formation of (17Z)-protosta-17(20),24-dien-3beta-ol.
1900582	o-orsellinic acid metabolic process	P	The chemical reactions and pathways involving o-orsellinic acid.
1900583	o-orsellinic acid catabolic process	P	The chemical reactions and pathways resulting in the breakdown of o-orsellinic acid.
1900584	o-orsellinic acid biosynthetic process	P	The chemical reactions and pathways resulting in the formation of o-orsellinic acid.
1900585	arugosin metabolic process	P	The chemical reactions and pathways involving arugosin.
1900586	arugosin catabolic process	P	The chemical reactions and pathways resulting in the breakdown of arugosin.
1900587	arugosin biosynthetic process	P	The chemical reactions and pathways resulting in the formation of arugosin.
1900588	violaceol I metabolic process	P	The chemical reactions and pathways involving violaceol I.
1900589	violaceol I catabolic process	P	The chemical reactions and pathways resulting in the breakdown of violaceol I.
1900590	violaceol I biosynthetic process	P	The chemical reactions and pathways resulting in the formation of violaceol I.
1900591	violaceol II metabolic process	P	The chemical reactions and pathways involving violaceol II.
1900592	violaceol II catabolic process	P	The chemical reactions and pathways resulting in the breakdown of violaceol II.
1900593	violaceol II biosynthetic process	P	The chemical reactions and pathways resulting in the formation of violaceol II.
1900594	(+)-kotanin metabolic process	P	The chemical reactions and pathways involving (+)-kotanin.
1900595	(+)-kotanin catabolic process	P	The chemical reactions and pathways resulting in the breakdown of (+)-kotanin.
1900596	(+)-kotanin biosynthetic process	P	The chemical reactions and pathways resulting in the formation of (+)-kotanin.
1900597	demethylkotanin metabolic process	P	The chemical reactions and pathways involving demethylkotanin.
1900598	demethylkotanin catabolic process	P	The chemical reactions and pathways resulting in the breakdown of demethylkotanin.
1900599	demethylkotanin biosynthetic process	P	The chemical reactions and pathways resulting in the formation of demethylkotanin.
1900600	endocrocin metabolic process	P	The chemical reactions and pathways involving endocrocin.
1900601	endocrocin catabolic process	P	The chemical reactions and pathways resulting in the breakdown of endocrocin.
1900602	endocrocin biosynthetic process	P	The chemical reactions and pathways resulting in the formation of endocrocin.
1900603	tensidol A metabolic process	P	The chemical reactions and pathways involving tensidol A.
1900604	tensidol A catabolic process	P	The chemical reactions and pathways resulting in the breakdown of tensidol A.
1900605	tensidol A biosynthetic process	P	The chemical reactions and pathways resulting in the formation of tensidol A.
1900606	tensidol B metabolic process	P	The chemical reactions and pathways involving tensidol B.
1900607	tensidol B catabolic process	P	The chemical reactions and pathways resulting in the breakdown of tensidol B.
1900608	tensidol B biosynthetic process	P	The chemical reactions and pathways resulting in the formation of tensidol B.
1900609	F-9775A metabolic process	P	The chemical reactions and pathways involving F-9775A.
1900610	F-9775A catabolic process	P	The chemical reactions and pathways resulting in the breakdown of F-9775A.
1900611	F-9775A biosynthetic process	P	The chemical reactions and pathways resulting in the formation of F-9775A.
1900612	F-9775B metabolic process	P	The chemical reactions and pathways involving F-9775B.
1900613	F-9775B catabolic process	P	The chemical reactions and pathways resulting in the breakdown of F-9775B.
1900614	F-9775B biosynthetic process	P	The chemical reactions and pathways resulting in the formation of F-9775B.
1900615	emericellamide A metabolic process	P	The chemical reactions and pathways involving emericellamide A.
1900616	emericellamide A catabolic process	P	The chemical reactions and pathways resulting in the breakdown of emericellamide A.
1900617	emericellamide A biosynthetic process	P	The chemical reactions and pathways resulting in the formation of emericellamide A.
1900618	regulation of shoot system morphogenesis	P	Any process that modulates the frequency, rate or extent of shoot morphogenesis.
1900619	acetate ester metabolic process	P	The chemical reactions and pathways involving an acetate ester, any carboxylic ester where the carboxylic acid component is acetic acid.
1900620	acetate ester biosynthetic process	P	The chemical reactions and pathways resulting in the formation of an acetate esteran acetate ester, any carboxylic ester where the carboxylic acid component is acetic acid.
1900621	regulation of transcription from RNA polymerase II promoter by calcium-mediated signaling	P	Calcium-mediated signaling that results in regulation of transcription from an RNA polymerase II promoter.
1900622	positive regulation of transcription from RNA polymerase II promoter by calcium-mediated signaling	P	Calcium-mediated signaling that results in positive regulation of transcription from an RNA polymerase II promoter.
1900623	regulation of monocyte aggregation	P	Any process that modulates the frequency, rate or extent of monocyte aggregation.
1900624	negative regulation of monocyte aggregation	P	Any process that stops, prevents or reduces the frequency, rate or extent of monocyte aggregation.
1900625	positive regulation of monocyte aggregation	P	Any process that activates or increases the frequency, rate or extent of monocyte aggregation.
1900626	regulation of arugosin biosynthetic process	P	Any process that modulates the frequency, rate or extent of arugosin biosynthetic process.
1900627	negative regulation of arugosin biosynthetic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of arugosin biosynthetic process.
1900628	positive regulation of arugosin biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of arugosin biosynthetic process.
1900629	methanophenazine metabolic process	P	The chemical reactions and pathways involving methanophenazine.
1900630	methanophenazine biosynthetic process	P	The chemical reactions and pathways resulting in the formation of methanophenazine.
1900631	tridecane metabolic process	P	The chemical reactions and pathways involving tridecane.
1900632	tridecane biosynthetic process	P	The chemical reactions and pathways resulting in the formation of tridecane.
1900633	pentadecane metabolic process	P	The chemical reactions and pathways involving pentadecane.
1900634	pentadecane biosynthetic process	P	The chemical reactions and pathways resulting in the formation of pentadecane.
1900635	heptadecane metabolic process	P	The chemical reactions and pathways involving heptadecane.
1900636	heptadecane biosynthetic process	P	The chemical reactions and pathways resulting in the formation of heptadecane.
1900637	regulation of asperfuranone biosynthetic process	P	Any process that modulates the frequency, rate or extent of asperfuranone biosynthetic process.
1900638	negative regulation of asperfuranone biosynthetic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of asperfuranone biosynthetic process.
1900639	positive regulation of asperfuranone biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of asperfuranone biosynthetic process.
1900640	regulation of austinol biosynthetic process	P	Any process that modulates the frequency, rate or extent of austinol biosynthetic process.
1900641	negative regulation of austinol biosynthetic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of austinol biosynthetic process.
1900642	positive regulation of austinol biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of austinol biosynthetic process.
1900643	regulation of chanoclavine-I biosynthetic process	P	Any process that modulates the frequency, rate or extent of chanoclavine-I biosynthetic process.
1900644	negative regulation of chanoclavine-I biosynthetic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of chanoclavine-I biosynthetic process.
1900645	positive regulation of chanoclavine-I biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of chanoclavine-I biosynthetic process.
1900646	regulation of chanoclavine-I aldehyde biosynthetic process	P	Any process that modulates the frequency, rate or extent of chanoclavine-I aldehyde biosynthetic process.
1900647	negative regulation of chanoclavine-I aldehyde biosynthetic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of chanoclavine-I aldehyde biosynthetic process.
1900648	positive regulation of chanoclavine-I aldehyde biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of chanoclavine-I aldehyde biosynthetic process.
1900649	regulation of dehydroaustinol biosynthetic process	P	Any process that modulates the frequency, rate or extent of dehydroaustinol biosynthetic process.
1900650	negative regulation of dehydroaustinol biosynthetic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of dehydroaustinol biosynthetic process.
1900651	positive regulation of dehydroaustinol biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of dehydroaustinol biosynthetic process.
1900652	regulation of demethylkotanin biosynthetic process	P	Any process that modulates the frequency, rate or extent of demethylkotanin biosynthetic process.
1900653	negative regulation of demethylkotanin biosynthetic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of demethylkotanin biosynthetic process.
1900654	positive regulation of demethylkotanin biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of demethylkotanin biosynthetic process.
1900655	regulation of diorcinol biosynthetic process	P	Any process that modulates the frequency, rate or extent of diorcinol biosynthetic process.
1900656	negative regulation of diorcinol biosynthetic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of diorcinol biosynthetic process.
1900657	positive regulation of diorcinol biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of diorcinol biosynthetic process.
1900658	regulation of emericellamide biosynthetic process	P	Any process that modulates the frequency, rate or extent of emericellamide biosynthetic process.
1900659	negative regulation of emericellamide biosynthetic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of emericellamide biosynthetic process.
1900660	positive regulation of emericellamide biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of emericellamide biosynthetic process.
1900661	regulation of emericellamide A biosynthetic process	P	Any process that modulates the frequency, rate or extent of emericellamide A biosynthetic process.
1900662	negative regulation of emericellamide A biosynthetic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of emericellamide A biosynthetic process.
1900663	positive regulation of emericellamide A biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of emericellamide A biosynthetic process.
1900664	regulation of emodin biosynthetic process	P	Any process that modulates the frequency, rate or extent of emodin biosynthetic process.
1900665	negative regulation of emodin biosynthetic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of emodin biosynthetic process.
1900666	positive regulation of emodin biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of emodin biosynthetic process.
1900667	regulation of endocrocin biosynthetic process	P	Any process that modulates the frequency, rate or extent of endocrocin biosynthetic process.
1900668	negative regulation of endocrocin biosynthetic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of endocrocin biosynthetic process.
1900669	positive regulation of endocrocin biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of endocrocin biosynthetic process.
1900670	regulation of F-9775A biosynthetic process	P	Any process that modulates the frequency, rate or extent of F-9775A biosynthetic process.
1900671	negative regulation of F-9775A biosynthetic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of F-9775A biosynthetic process.
1900672	positive regulation of F-9775A biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of F-9775A biosynthetic process.
1900673	olefin metabolic process	P	The chemical reactions and pathways involving olefin.
1900674	olefin biosynthetic process	P	The chemical reactions and pathways resulting in the formation of olefin.
1900675	regulation of F-9775B biosynthetic process	P	Any process that modulates the frequency, rate or extent of F-9775B biosynthetic process.
1900676	negative regulation of F-9775B biosynthetic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of F-9775B biosynthetic process.
1900677	positive regulation of F-9775B biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of F-9775B biosynthetic process.
1900678	regulation of ferricrocin biosynthetic process	P	Any process that modulates the frequency, rate or extent of ferricrocin biosynthetic process.
1900679	negative regulation of ferricrocin biosynthetic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of ferricrocin biosynthetic process.
1900680	positive regulation of ferricrocin biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of ferricrocin biosynthetic process.
1900681	octadecene metabolic process	P	The chemical reactions and pathways involving octadecene.
1900682	octadecene biosynthetic process	P	The chemical reactions and pathways resulting in the formation of octadecene.
1900683	regulation of fumonisin biosynthetic process	P	Any process that modulates the frequency, rate or extent of fumonisin biosynthetic process.
1900684	negative regulation of fumonisin biosynthetic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of fumonisin biosynthetic process.
1900685	positive regulation of fumonisin biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of fumonisin biosynthetic process.
1900686	regulation of gerfelin biosynthetic process	P	Any process that modulates the frequency, rate or extent of gerfelin biosynthetic process.
1900687	negative regulation of gerfelin biosynthetic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of gerfelin biosynthetic process.
1900688	positive regulation of gerfelin biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of gerfelin biosynthetic process.
1900689	regulation of gliotoxin biosynthetic process	P	Any process that modulates the frequency, rate or extent of gliotoxin biosynthetic process.
1900690	negative regulation of gliotoxin biosynthetic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of gliotoxin biosynthetic process.
1900691	positive regulation of gliotoxin biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of gliotoxin biosynthetic process.
1900692	regulation of (+)-kotanin biosynthetic process	P	Any process that modulates the frequency, rate or extent of (+)-kotanin biosynthetic process.
1900693	negative regulation of (+)-kotanin biosynthetic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of (+)-kotanin biosynthetic process.
1900694	positive regulation of (+)-kotanin biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of (+)-kotanin biosynthetic process.
1900695	regulation of N',N'',N'''-triacetylfusarinine C biosynthetic process	P	Any process that modulates the frequency, rate or extent of N',N'',N'''-triacetylfusarinine C biosynthetic process.
1900696	negative regulation of N',N'',N'''-triacetylfusarinine C biosynthetic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of N',N'',N'''-triacetylfusarinine C biosynthetic process.
1900697	positive regulation of N',N'',N'''-triacetylfusarinine C biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of N',N'',N'''-triacetylfusarinine C biosynthetic process.
1900698	regulation of o-orsellinic acid biosynthetic process	P	Any process that modulates the frequency, rate or extent of o-orsellinic acid biosynthetic process.
1900699	negative regulation of o-orsellinic acid biosynthetic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of o-orsellinic acid biosynthetic process.
1900700	positive regulation of o-orsellinic acid biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of o-orsellinic acid biosynthetic process.
1900701	regulation of orcinol biosynthetic process	P	Any process that modulates the frequency, rate or extent of orcinol biosynthetic process.
1900702	negative regulation of orcinol biosynthetic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of orcinol biosynthetic process.
1900703	positive regulation of orcinol biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of orcinol biosynthetic process.
1900704	regulation of siderophore biosynthetic process	P	Any process that modulates the frequency, rate or extent of siderophore biosynthetic process.
1900705	negative regulation of siderophore biosynthetic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of siderophore biosynthetic process.
1900706	positive regulation of siderophore biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of siderophore biosynthetic process.
1900707	regulation of tensidol A biosynthetic process	P	Any process that modulates the frequency, rate or extent of tensidol A biosynthetic process.
1900708	negative regulation of tensidol A biosynthetic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of tensidol A biosynthetic process.
1900709	positive regulation of tensidol A biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of tensidol A biosynthetic process.
1900710	regulation of tensidol B biosynthetic process	P	Any process that modulates the frequency, rate or extent of tensidol B biosynthetic process.
1900711	negative regulation of tensidol B biosynthetic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of tensidol B biosynthetic process.
1900712	positive regulation of tensidol B biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of tensidol B biosynthetic process.
1900713	regulation of violaceol I biosynthetic process	P	Any process that modulates the frequency, rate or extent of violaceol I biosynthetic process.
1900714	negative regulation of violaceol I biosynthetic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of violaceol I biosynthetic process.
1900715	positive regulation of violaceol I biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of violaceol I biosynthetic process.
1900716	regulation of violaceol II biosynthetic process	P	Any process that modulates the frequency, rate or extent of violaceol II biosynthetic process.
1900717	negative regulation of violaceol II biosynthetic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of violaceol II biosynthetic process.
1900718	positive regulation of violaceol II biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of violaceol II biosynthetic process.
1900719	regulation of uterine smooth muscle relaxation	P	Any process that modulates the frequency, rate or extent of uterine smooth muscle relaxation.
1900720	negative regulation of uterine smooth muscle relaxation	P	Any process that stops, prevents or reduces the frequency, rate or extent of uterine smooth muscle relaxation.
1900721	positive regulation of uterine smooth muscle relaxation	P	Any process that activates or increases the frequency, rate or extent of uterine smooth muscle relaxation.
1900722	regulation of protein adenylylation	P	Any process that modulates the frequency, rate or extent of protein adenylylation.
1900723	negative regulation of protein adenylylation	P	Any process that stops, prevents or reduces the frequency, rate or extent of protein adenylylation.
1900724	positive regulation of protein adenylylation	P	Any process that activates or increases the frequency, rate or extent of protein adenylylation.
1900725	osmoregulated periplasmic glucan metabolic process	P	The chemical reactions and pathways involving osmoregulated periplasmic glucan.
1900726	osmoregulated periplasmic glucan catabolic process	P	The chemical reactions and pathways resulting in the breakdown of osmoregulated periplasmic glucan.
1900727	osmoregulated periplasmic glucan biosynthetic process	P	The chemical reactions and pathways resulting in the formation of osmoregulated periplasmic glucan.
1900728	cardiac neural crest cell delamination involved in outflow tract morphogenesis	P	Any cardiac neural crest cell delamination that is involved in outflow tract morphogenesis.
1900729	regulation of adenylate cyclase-inhibiting opioid receptor signaling pathway	P	Any process that modulates the frequency, rate or extent of adenylate cyclase-inhibiting opioid receptor signaling pathway.
1900730	negative regulation of adenylate cyclase-inhibiting opioid receptor signaling pathway	P	Any process that stops, prevents or reduces the frequency, rate or extent of adenylate cyclase-inhibiting opioid receptor signaling pathway.
1900731	positive regulation of adenylate cyclase-inhibiting opioid receptor signaling pathway	P	Any process that activates or increases the frequency, rate or extent of adenylate cyclase-inhibiting opioid receptor signaling pathway.
1900732	regulation of polyketide biosynthetic process	P	Any process that modulates the frequency, rate or extent of polyketide biosynthetic process.
1900733	negative regulation of polyketide biosynthetic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of polyketide biosynthetic process.
1900734	positive regulation of polyketide biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of polyketide biosynthetic process.
1900735	positive regulation of flocculation	P	Any process that activates or increases the frequency, rate or extent of flocculation.
1900736	regulation of phospholipase C-activating G-protein coupled receptor signaling pathway	P	Any process that modulates the frequency, rate or extent of phospholipase C-activating G-protein coupled receptor signaling pathway.
1900737	negative regulation of phospholipase C-activating G-protein coupled receptor signaling pathway	P	Any process that stops, prevents or reduces the frequency, rate or extent of phospholipase C-activating G-protein coupled receptor signaling pathway.
1900738	positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway	P	Any process that activates or increases the frequency, rate or extent of phospholipase C-activating G-protein coupled receptor signaling pathway.
1900739	regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway	P	Any process that modulates the frequency, rate or extent of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway.
1900740	positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway	P	Any process that activates or increases the frequency, rate or extent of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway.
1900741	regulation of filamentous growth of a population of unicellular organisms in response to pH	P	Any process that modulates the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to pH.
1900742	negative regulation of filamentous growth of a population of unicellular organisms in response to pH	P	Any process that stops, prevents or reduces the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to pH.
1900743	positive regulation of filamentous growth of a population of unicellular organisms in response to pH	P	Any process that activates or increases the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to pH.
1900744	regulation of p38MAPK cascade	P	Any process that modulates the frequency, rate or extent of p38MAPK cascade.
1900745	positive regulation of p38MAPK cascade	P	Any process that activates or increases the frequency, rate or extent of p38MAPK cascade.
1900746	regulation of vascular endothelial growth factor signaling pathway	P	Any process that modulates the frequency, rate or extent of vascular endothelial growth factor signaling pathway.
1900747	negative regulation of vascular endothelial growth factor signaling pathway	P	Any process that stops, prevents or reduces the frequency, rate or extent of vascular endothelial growth factor signaling pathway.
1900748	positive regulation of vascular endothelial growth factor signaling pathway	P	Any process that activates or increases the frequency, rate or extent of vascular endothelial growth factor signaling pathway.
1900749	(R)-carnitine transport	P	The directed movement of a (R)-carnitine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
1900750	oligopeptide binding	F	Interacting selectively and non-covalently with an oligopeptide.
1900751	4-(trimethylammonio)butanoate transport	P	The directed movement of a 4-(trimethylammonio)butanoate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
1900752	malonic acid transport	P	The directed movement of a malonic acid into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
1900753	doxorubicin transport	P	The directed movement of a doxorubicin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
1900754	4-hydroxyphenylacetate transport	P	The directed movement of a 4-hydroxyphenylacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
1900756	protein processing in phagocytic vesicle	P	Protein processing that takes place in the phagosome. Most protein processing in the phagosome represents protein degradation.
1900757	regulation of D-amino-acid oxidase activity	P	Any process that modulates the frequency, rate or extent of D-amino-acid oxidase activity.
1900758	negative regulation of D-amino-acid oxidase activity	P	Any process that stops, prevents or reduces the frequency, rate or extent of D-amino-acid oxidase activity.
1900759	positive regulation of D-amino-acid oxidase activity	P	Any process that activates or increases the frequency, rate or extent of D-amino-acid oxidase activity.
1900760	negative regulation of sterigmatocystin biosynthetic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of sterigmatocystin biosynthetic process.
1900761	averantin metabolic process	P	The chemical reactions and pathways involving averantin.
1900762	averantin catabolic process	P	The chemical reactions and pathways resulting in the breakdown of averantin.
1900763	averantin biosynthetic process	P	The chemical reactions and pathways resulting in the formation of averantin.
1900764	emericellin metabolic process	P	The chemical reactions and pathways involving emericellin.
1900765	emericellin catabolic process	P	The chemical reactions and pathways resulting in the breakdown of emericellin.
1900766	emericellin biosynthetic process	P	The chemical reactions and pathways resulting in the formation of emericellin.
1900767	fonsecin metabolic process	P	The chemical reactions and pathways involving fonsecin.
1900768	fonsecin catabolic process	P	The chemical reactions and pathways resulting in the breakdown of fonsecin.
1900769	fonsecin biosynthetic process	P	The chemical reactions and pathways resulting in the formation of fonsecin.
1900770	fumitremorgin B metabolic process	P	The chemical reactions and pathways involving fumitremorgin B.
1900771	fumitremorgin B catabolic process	P	The chemical reactions and pathways resulting in the breakdown of fumitremorgin B.
1900772	fumitremorgin B biosynthetic process	P	The chemical reactions and pathways resulting in the formation of fumitremorgin B.
1900773	fumiquinazoline metabolic process	P	The chemical reactions and pathways involving fumiquinazoline.
1900774	fumiquinazoline catabolic process	P	The chemical reactions and pathways resulting in the breakdown of fumiquinazoline.
1900775	fumiquinazoline biosynthetic process	P	The chemical reactions and pathways resulting in the formation of fumiquinazoline.
1900776	fumiquinazoline A metabolic process	P	The chemical reactions and pathways involving fumiquinazoline A.
1900777	fumiquinazoline A catabolic process	P	The chemical reactions and pathways resulting in the breakdown of fumiquinazoline A.
1900778	fumiquinazoline A biosynthetic process	P	The chemical reactions and pathways resulting in the formation of fumiquinazoline A.
1900779	fumiquinazoline C metabolic process	P	The chemical reactions and pathways involving fumiquinazoline C.
1900780	fumiquinazoline C catabolic process	P	The chemical reactions and pathways resulting in the breakdown of fumiquinazoline C.
1900781	fumiquinazoline C biosynthetic process	P	The chemical reactions and pathways resulting in the formation of fumiquinazoline C.
1900782	fumiquinazoline F metabolic process	P	The chemical reactions and pathways involving fumiquinazoline F.
1900783	fumiquinazoline F catabolic process	P	The chemical reactions and pathways resulting in the breakdown of fumiquinazoline F.
1900784	fumiquinazoline F biosynthetic process	P	The chemical reactions and pathways resulting in the formation of fumiquinazoline F.
1900785	naphtho-gamma-pyrone metabolic process	P	The chemical reactions and pathways involving naphtho-gamma-pyrone.
1900786	naphtho-gamma-pyrone catabolic process	P	The chemical reactions and pathways resulting in the breakdown of naphtho-gamma-pyrone.
1900787	naphtho-gamma-pyrone biosynthetic process	P	The chemical reactions and pathways resulting in the formation of naphtho-gamma-pyrone.
1900788	pseurotin A metabolic process	P	The chemical reactions and pathways involving pseurotin A.
1900789	pseurotin A catabolic process	P	The chemical reactions and pathways resulting in the breakdown of pseurotin A.
1900790	pseurotin A biosynthetic process	P	The chemical reactions and pathways resulting in the formation of pseurotin A.
1900791	shamixanthone metabolic process	P	The chemical reactions and pathways involving shamixanthone.
1900792	shamixanthone catabolic process	P	The chemical reactions and pathways resulting in the breakdown of shamixanthone.
1900793	shamixanthone biosynthetic process	P	The chemical reactions and pathways resulting in the formation of shamixanthone.
1900794	terrequinone A metabolic process	P	The chemical reactions and pathways involving terrequinone A.
1900795	terrequinone A catabolic process	P	The chemical reactions and pathways resulting in the breakdown of terrequinone A.
1900796	terrequinone A biosynthetic process	P	The chemical reactions and pathways resulting in the formation of terrequinone A.
1900797	cordyol C metabolic process	P	The chemical reactions and pathways involving cordyol C.
1900798	cordyol C catabolic process	P	The chemical reactions and pathways resulting in the breakdown of cordyol C.
1900799	cordyol C biosynthetic process	P	The chemical reactions and pathways resulting in the formation of cordyol C.
1900800	cspyrone B1 metabolic process	P	The chemical reactions and pathways involving cspyrone B1.
1900801	cspyrone B1 catabolic process	P	The chemical reactions and pathways resulting in the breakdown of cspyrone B1.
1900802	cspyrone B1 biosynthetic process	P	The chemical reactions and pathways resulting in the formation of cspyrone B1.
1900803	brevianamide F metabolic process	P	The chemical reactions and pathways involving brevianamide F.
1900804	brevianamide F catabolic process	P	The chemical reactions and pathways resulting in the breakdown of brevianamide F.
1900805	brevianamide F biosynthetic process	P	The chemical reactions and pathways resulting in the formation of brevianamide F.
1900806	ergot alkaloid catabolic process	P	The chemical reactions and pathways resulting in the breakdown of ergot alkaloid.
1900807	fumigaclavine C metabolic process	P	The chemical reactions and pathways involving fumigaclavine C.
1900808	fumigaclavine C catabolic process	P	The chemical reactions and pathways resulting in the breakdown of fumigaclavine C.
1900809	fumigaclavine C biosynthetic process	P	The chemical reactions and pathways resulting in the formation of fumigaclavine C.
1900810	helvolic acid metabolic process	P	The chemical reactions and pathways involving helvolic acid.
1900811	helvolic acid catabolic process	P	The chemical reactions and pathways resulting in the breakdown of helvolic acid.
1900812	helvolic acid biosynthetic process	P	The chemical reactions and pathways resulting in the formation of helvolic acid.
1900813	monodictyphenone metabolic process	P	The chemical reactions and pathways involving monodictyphenone.
1900814	monodictyphenone catabolic process	P	The chemical reactions and pathways resulting in the breakdown of monodictyphenone.
1900815	monodictyphenone biosynthetic process	P	The chemical reactions and pathways resulting in the formation of monodictyphenone.
1900816	ochratoxin A metabolic process	P	The chemical reactions and pathways involving ochratoxin A.
1900817	ochratoxin A catabolic process	P	The chemical reactions and pathways resulting in the breakdown of ochratoxin A.
1900818	ochratoxin A biosynthetic process	P	The chemical reactions and pathways resulting in the formation of ochratoxin A.
1900819	orlandin metabolic process	P	The chemical reactions and pathways involving orlandin.
1900820	orlandin catabolic process	P	The chemical reactions and pathways resulting in the breakdown of orlandin.
1900821	orlandin biosynthetic process	P	The chemical reactions and pathways resulting in the formation of orlandin.
1900822	regulation of ergot alkaloid biosynthetic process	P	Any process that modulates the frequency, rate or extent of ergot alkaloid biosynthetic process.
1900823	negative regulation of ergot alkaloid biosynthetic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of ergot alkaloid biosynthetic process.
1900824	positive regulation of ergot alkaloid biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of ergot alkaloid biosynthetic process.
1900825	regulation of membrane depolarization during cardiac muscle cell action potential	P	Any process that modulates the frequency, rate or extent of membrane depolarization during a cardiac muscle cell action potential.
1900826	negative regulation of membrane depolarization during cardiac muscle cell action potential	P	Any process that stops, prevents or reduces the frequency, rate or extent of membrane depolarization during a cardiac muscle cell action potential.
1900827	positive regulation of membrane depolarization during cardiac muscle cell action potential	P	Any process that activates or increases the frequency, rate or extent of membrane depolarization during a cardiac muscle cell action potential.
1900828	D-tyrosine metabolic process	P	The chemical reactions and pathways involving D-tyrosine.
1900829	D-tyrosine catabolic process	P	The chemical reactions and pathways resulting in the breakdown of D-tyrosine.
1900830	D-tyrosine biosynthetic process	P	The chemical reactions and pathways resulting in the formation of D-tyrosine.
1900831	D-leucine metabolic process	P	The chemical reactions and pathways involving D-leucine.
1900832	D-leucine catabolic process	P	The chemical reactions and pathways resulting in the breakdown of D-leucine.
1900833	D-leucine biosynthetic process	P	The chemical reactions and pathways resulting in the formation of D-leucine.
1900834	regulation of emericellin biosynthetic process	P	Any process that modulates the frequency, rate or extent of emericellin biosynthetic process.
1900835	negative regulation of emericellin biosynthetic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of emericellin biosynthetic process.
1900836	positive regulation of emericellin biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of emericellin biosynthetic process.
1900837	regulation of fumigaclavine C biosynthetic process	P	Any process that modulates the frequency, rate or extent of fumigaclavine C biosynthetic process.
1900838	negative regulation of fumigaclavine C biosynthetic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of fumigaclavine C biosynthetic process.
1900839	positive regulation of fumigaclavine C biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of fumigaclavine C biosynthetic process.
1900840	regulation of helvolic acid biosynthetic process	P	Any process that modulates the frequency, rate or extent of helvolic acid biosynthetic process.
1900841	negative regulation of helvolic acid biosynthetic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of helvolic acid biosynthetic process.
1900842	positive regulation of helvolic acid biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of helvolic acid biosynthetic process.
1900843	regulation of monodictyphenone biosynthetic process	P	Any process that modulates the frequency, rate or extent of monodictyphenone biosynthetic process.
1900844	negative regulation of monodictyphenone biosynthetic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of monodictyphenone biosynthetic process.
1900845	positive regulation of monodictyphenone biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of monodictyphenone biosynthetic process.
1900846	regulation of naphtho-gamma-pyrone biosynthetic process	P	Any process that modulates the frequency, rate or extent of naphtho-gamma-pyrone biosynthetic process.
1900847	negative regulation of naphtho-gamma-pyrone biosynthetic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of naphtho-gamma-pyrone biosynthetic process.
1900848	positive regulation of naphtho-gamma-pyrone biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of naphtho-gamma-pyrone biosynthetic process.
1900849	regulation of pseurotin A biosynthetic process	P	Any process that modulates the frequency, rate or extent of pseurotin A biosynthetic process.
1900850	negative regulation of pseurotin A biosynthetic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of pseurotin A biosynthetic process.
1900851	positive regulation of pseurotin A biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of pseurotin A biosynthetic process.
1900852	regulation of terrequinone A biosynthetic process	P	Any process that modulates the frequency, rate or extent of terrequinone A biosynthetic process.
1900853	negative regulation of terrequinone A biosynthetic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of terrequinone A biosynthetic process.
1900854	positive regulation of terrequinone A biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of terrequinone A biosynthetic process.
1900855	regulation of fumitremorgin B biosynthetic process	P	Any process that modulates the frequency, rate or extent of fumitremorgin B biosynthetic process.
1900856	negative regulation of fumitremorgin B biosynthetic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of fumitremorgin B biosynthetic process.
1900857	positive regulation of fumitremorgin B biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of fumitremorgin B biosynthetic process.
1900858	regulation of brevianamide F biosynthetic process	P	Any process that modulates the frequency, rate or extent of brevianamide F biosynthetic process.
1900859	negative regulation of brevianamide F biosynthetic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of brevianamide F biosynthetic process.
1900860	positive regulation of brevianamide F biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of brevianamide F biosynthetic process.
1900861	regulation of cordyol C biosynthetic process	P	Any process that modulates the frequency, rate or extent of cordyol C biosynthetic process.
1900862	negative regulation of cordyol C biosynthetic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of cordyol C biosynthetic process.
1900863	positive regulation of cordyol C biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of cordyol C biosynthetic process.
1900864	mitochondrial RNA modification	P	Any RNA modification that takes place in mitochondrion.
1900865	chloroplast RNA modification	P	Any RNA modification that takes place in chloroplast.
1900866	glycolate transport	P	The directed movement of a glycolate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
1900867	sarcinapterin metabolic process	P	The chemical reactions and pathways involving sarcinapterin.
1900868	sarcinapterin biosynthetic process	P	The chemical reactions and pathways resulting in the formation of sarcinapterin.
1900869	tatiopterin metabolic process	P	The chemical reactions and pathways involving tatiopterin.
1900870	tatiopterin biosynthetic process	P	The chemical reactions and pathways resulting in the formation of tatiopterin.
1900871	chloroplast mRNA modification	P	The covalent alteration within the chloroplast of one or more nucleotides within an mRNA to produce an mRNA molecule with a sequence that differs from that coded genetically.
1900872	pentadec-1-ene metabolic process	P	The chemical reactions and pathways involving pentadec-1-ene.
1900873	pentadec-1-ene biosynthetic process	P	The chemical reactions and pathways resulting in the formation of pentadec-1-ene.
1900874	heptadec-1-ene metabolic process	P	The chemical reactions and pathways involving heptadec-1-ene.
1900875	heptadec-1-ene biosynthetic process	P	The chemical reactions and pathways resulting in the formation of heptadec-1-ene.
1900876	nonadec-1-ene metabolic process	P	The chemical reactions and pathways involving nonadec-1-ene.
1900877	nonadec-1-ene biosynthetic process	P	The chemical reactions and pathways resulting in the formation of nonadec-1-ene.
1900878	(Z)-nonadeca-1,14-diene metabolic process	P	The chemical reactions and pathways involving (Z)-nonadeca-1,14-diene.
1900879	(Z)-nonadeca-1,14-diene biosynthetic process	P	The chemical reactions and pathways resulting in the formation of (Z)-nonadeca-1,14-diene.
1900880	18-methylnonadec-1-ene metabolic process	P	The chemical reactions and pathways involving 18-methylnonadec-1-ene.
1900881	18-methylnonadec-1-ene biosynthetic process	P	The chemical reactions and pathways resulting in the formation of 18-methylnonadec-1-ene.
1900882	17-methylnonadec-1-ene metabolic process	P	The chemical reactions and pathways involving 17-methylnonadec-1-ene.
1900883	17-methylnonadec-1-ene biosynthetic process	P	The chemical reactions and pathways resulting in the formation of 17-methylnonadec-1-ene.
1900884	regulation of tridecane biosynthetic process	P	Any process that modulates the frequency, rate or extent of tridecane biosynthetic process.
1900885	negative regulation of tridecane biosynthetic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of tridecane biosynthetic process.
1900886	positive regulation of tridecane biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of tridecane biosynthetic process.
1900887	regulation of pentadecane biosynthetic process	P	Any process that modulates the frequency, rate or extent of pentadecane biosynthetic process.
1900888	negative regulation of pentadecane biosynthetic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of pentadecane biosynthetic process.
1900889	positive regulation of pentadecane biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of pentadecane biosynthetic process.
1900890	regulation of pentadecane metabolic process	P	Any process that modulates the frequency, rate or extent of pentadecane metabolic process.
1900891	negative regulation of pentadecane metabolic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of pentadecane metabolic process.
1900892	positive regulation of pentadecane metabolic process	P	Any process that activates or increases the frequency, rate or extent of pentadecane metabolic process.
1900893	regulation of tridecane metabolic process	P	Any process that modulates the frequency, rate or extent of tridecane metabolic process.
1900894	negative regulation of tridecane metabolic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of tridecane metabolic process.
1900895	positive regulation of tridecane metabolic process	P	Any process that activates or increases the frequency, rate or extent of tridecane metabolic process.
1900896	regulation of heptadecane biosynthetic process	P	Any process that modulates the frequency, rate or extent of heptadecane biosynthetic process.
1900897	negative regulation of heptadecane biosynthetic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of heptadecane biosynthetic process.
1900898	positive regulation of heptadecane biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of heptadecane biosynthetic process.
1900899	regulation of heptadecane metabolic process	P	Any process that modulates the frequency, rate or extent of heptadecane metabolic process.
1900900	negative regulation of heptadecane metabolic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of heptadecane metabolic process.
1900901	positive regulation of heptadecane metabolic process	P	Any process that activates or increases the frequency, rate or extent of heptadecane metabolic process.
1900902	regulation of hexadecanal biosynthetic process	P	Any process that modulates the frequency, rate or extent of hexadecanal biosynthetic process.
1900903	negative regulation of hexadecanal biosynthetic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of hexadecanal biosynthetic process.
1900904	positive regulation of hexadecanal biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of hexadecanal biosynthetic process.
1900905	regulation of hexadecanal metabolic process	P	Any process that modulates the frequency, rate or extent of hexadecanal metabolic process.
1900906	negative regulation of hexadecanal metabolic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of hexadecanal metabolic process.
1900907	positive regulation of hexadecanal metabolic process	P	Any process that activates or increases the frequency, rate or extent of hexadecanal metabolic process.
1900908	regulation of olefin metabolic process	P	Any process that modulates the frequency, rate or extent of olefin metabolic process.
1900909	negative regulation of olefin metabolic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of olefin metabolic process.
1900910	positive regulation of olefin metabolic process	P	Any process that activates or increases the frequency, rate or extent of olefin metabolic process.
1900911	regulation of olefin biosynthetic process	P	Any process that modulates the frequency, rate or extent of olefin biosynthetic process.
1900912	negative regulation of olefin biosynthetic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of olefin biosynthetic process.
1900913	positive regulation of olefin biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of olefin biosynthetic process.
1900914	regulation of octadecene biosynthetic process	P	Any process that modulates the frequency, rate or extent of octadecene biosynthetic process.
1900915	negative regulation of octadecene biosynthetic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of octadecene biosynthetic process.
1900916	positive regulation of octadecene biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of octadecene biosynthetic process.
1900917	regulation of octadecene metabolic process	P	Any process that modulates the frequency, rate or extent of octadecene metabolic process.
1900918	negative regulation of octadecene metabolic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of octadecene metabolic process.
1900919	positive regulation of octadecene metabolic process	P	Any process that activates or increases the frequency, rate or extent of octadecene metabolic process.
1900920	regulation of L-glutamate import	P	Any process that modulates the frequency, rate or extent of L-glutamate import.
1900921	negative regulation of L-glutamate import	P	Any process that stops, prevents or reduces the frequency, rate or extent of L-glutamate import.
1900922	positive regulation of L-glutamate import	P	Any process that activates or increases the frequency, rate or extent of L-glutamate import.
1900923	regulation of glycine import	P	Any process that modulates the frequency, rate or extent of glycine import.
1900924	negative regulation of glycine import	P	Any process that stops, prevents or reduces the frequency, rate or extent of glycine import.
1900925	positive regulation of glycine import	P	Any process that activates or increases the frequency, rate or extent of glycine import.
1900926	regulation of L-threonine import	P	Any process that modulates the frequency, rate or extent of L-threonine import.
1900927	negative regulation of L-threonine import	P	Any process that stops, prevents or reduces the frequency, rate or extent of L-threonine import.
1900928	positive regulation of L-threonine import	P	Any process that activates or increases the frequency, rate or extent of L-threonine import.
1900929	regulation of L-tyrosine import	P	Any process that modulates the frequency, rate or extent of L-tyrosine import.
1900930	negative regulation of L-tyrosine import	P	Any process that stops, prevents or reduces the frequency, rate or extent of L-tyrosine import.
1900931	positive regulation of L-tyrosine import	P	Any process that activates or increases the frequency, rate or extent of L-tyrosine import.
1900932	regulation of nonadec-1-ene metabolic process	P	Any process that modulates the frequency, rate or extent of nonadec-1-ene metabolic process.
1900933	negative regulation of nonadec-1-ene metabolic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of nonadec-1-ene metabolic process.
1900934	positive regulation of nonadec-1-ene metabolic process	P	Any process that activates or increases the frequency, rate or extent of nonadec-1-ene metabolic process.
1900935	regulation of nonadec-1-ene biosynthetic process	P	Any process that modulates the frequency, rate or extent of nonadec-1-ene biosynthetic process.
1900936	negative regulation of nonadec-1-ene biosynthetic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of nonadec-1-ene biosynthetic process.
1900937	positive regulation of nonadec-1-ene biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of nonadec-1-ene biosynthetic process.
1900938	regulation of (Z)-nonadeca-1,14-diene metabolic process	P	Any process that modulates the frequency, rate or extent of (Z)-nonadeca-1,14-diene metabolic process.
1900939	negative regulation of (Z)-nonadeca-1,14-diene metabolic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of (Z)-nonadeca-1,14-diene metabolic process.
1900940	positive regulation of (Z)-nonadeca-1,14-diene metabolic process	P	Any process that activates or increases the frequency, rate or extent of (Z)-nonadeca-1,14-diene metabolic process.
1900941	regulation of (Z)-nonadeca-1,14-diene biosynthetic process	P	Any process that modulates the frequency, rate or extent of (Z)-nonadeca-1,14-diene biosynthetic process.
1900942	negative regulation of (Z)-nonadeca-1,14-diene biosynthetic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of (Z)-nonadeca-1,14-diene biosynthetic process.
1900943	positive regulation of (Z)-nonadeca-1,14-diene biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of (Z)-nonadeca-1,14-diene biosynthetic process.
1900944	regulation of isoprene metabolic process	P	Any process that modulates the frequency, rate or extent of isoprene metabolic process.
1900945	negative regulation of isoprene metabolic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of isoprene metabolic process.
1900946	positive regulation of isoprene metabolic process	P	Any process that activates or increases the frequency, rate or extent of isoprene metabolic process.
1900947	regulation of isoprene biosynthetic process	P	Any process that modulates the frequency, rate or extent of isoprene biosynthetic process.
1900948	negative regulation of isoprene biosynthetic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of isoprene biosynthetic process.
1900949	positive regulation of isoprene biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of isoprene biosynthetic process.
1900950	regulation of 18-methylnonadec-1-ene biosynthetic process	P	Any process that modulates the frequency, rate or extent of 18-methylnonadec-1-ene biosynthetic process.
1900951	negative regulation of 18-methylnonadec-1-ene biosynthetic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of 18-methylnonadec-1-ene biosynthetic process.
1900952	positive regulation of 18-methylnonadec-1-ene biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of 18-methylnonadec-1-ene biosynthetic process.
1900953	regulation of 18-methylnonadec-1-ene metabolic process	P	Any process that modulates the frequency, rate or extent of 18-methylnonadec-1-ene metabolic process.
1900954	negative regulation of 18-methylnonadec-1-ene metabolic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of 18-methylnonadec-1-ene metabolic process.
1900955	positive regulation of 18-methylnonadec-1-ene metabolic process	P	Any process that activates or increases the frequency, rate or extent of 18-methylnonadec-1-ene metabolic process.
1900956	regulation of 17-methylnonadec-1-ene biosynthetic process	P	Any process that modulates the frequency, rate or extent of 17-methylnonadec-1-ene biosynthetic process.
1900957	negative regulation of 17-methylnonadec-1-ene biosynthetic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of 17-methylnonadec-1-ene biosynthetic process.
1900958	positive regulation of 17-methylnonadec-1-ene biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of 17-methylnonadec-1-ene biosynthetic process.
1900959	regulation of 17-methylnonadec-1-ene metabolic process	P	Any process that modulates the frequency, rate or extent of 17-methylnonadec-1-ene metabolic process.
1900960	negative regulation of 17-methylnonadec-1-ene metabolic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of 17-methylnonadec-1-ene metabolic process.
1900961	positive regulation of 17-methylnonadec-1-ene metabolic process	P	Any process that activates or increases the frequency, rate or extent of 17-methylnonadec-1-ene metabolic process.
1900962	regulation of methanophenazine biosynthetic process	P	Any process that modulates the frequency, rate or extent of methanophenazine biosynthetic process.
1900963	negative regulation of methanophenazine biosynthetic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of methanophenazine biosynthetic process.
1900964	positive regulation of methanophenazine biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of methanophenazine biosynthetic process.
1900965	regulation of methanophenazine metabolic process	P	Any process that modulates the frequency, rate or extent of methanophenazine metabolic process.
1900966	negative regulation of methanophenazine metabolic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of methanophenazine metabolic process.
1900967	positive regulation of methanophenazine metabolic process	P	Any process that activates or increases the frequency, rate or extent of methanophenazine metabolic process.
1900968	regulation of sarcinapterin metabolic process	P	Any process that modulates the frequency, rate or extent of sarcinapterin metabolic process.
1900969	negative regulation of sarcinapterin metabolic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of sarcinapterin metabolic process.
1900970	positive regulation of sarcinapterin metabolic process	P	Any process that activates or increases the frequency, rate or extent of sarcinapterin metabolic process.
1900971	regulation of sarcinapterin biosynthetic process	P	Any process that modulates the frequency, rate or extent of sarcinapterin biosynthetic process.
1900972	negative regulation of sarcinapterin biosynthetic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of sarcinapterin biosynthetic process.
1900973	positive regulation of sarcinapterin biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of sarcinapterin biosynthetic process.
1900974	regulation of tatiopterin biosynthetic process	P	Any process that modulates the frequency, rate or extent of tatiopterin biosynthetic process.
1900975	negative regulation of tatiopterin biosynthetic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of tatiopterin biosynthetic process.
1900976	positive regulation of tatiopterin biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of tatiopterin biosynthetic process.
1900977	regulation of tatiopterin metabolic process	P	Any process that modulates the frequency, rate or extent of tatiopterin metabolic process.
1900978	negative regulation of tatiopterin metabolic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of tatiopterin metabolic process.
1900979	positive regulation of tatiopterin metabolic process	P	Any process that activates or increases the frequency, rate or extent of tatiopterin metabolic process.
1900980	regulation of phenazine biosynthetic process	P	Any process that modulates the frequency, rate or extent of phenazine biosynthetic process.
1900981	negative regulation of phenazine biosynthetic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of phenazine biosynthetic process.
1900982	positive regulation of phenazine biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of phenazine biosynthetic process.
1900983	vindoline metabolic process	P	The chemical reactions and pathways involving vindoline.
1900984	vindoline catabolic process	P	The chemical reactions and pathways resulting in the breakdown of vindoline.
1900985	vindoline biosynthetic process	P	The chemical reactions and pathways resulting in the formation of vindoline.
1900986	ajmaline metabolic process	P	The chemical reactions and pathways involving ajmaline.
1900987	ajmaline catabolic process	P	The chemical reactions and pathways resulting in the breakdown of ajmaline.
1900988	ajmaline biosynthetic process	P	The chemical reactions and pathways resulting in the formation of ajmaline.
1900989	scopolamine metabolic process	P	The chemical reactions and pathways involving scopolamine.
1900990	scopolamine catabolic process	P	The chemical reactions and pathways resulting in the breakdown of scopolamine.
1900991	scopolamine biosynthetic process	P	The chemical reactions and pathways resulting in the formation of scopolamine.
1900992	(-)-secologanin metabolic process	P	The chemical reactions and pathways involving (-)-secologanin.
1900993	(-)-secologanin catabolic process	P	The chemical reactions and pathways resulting in the breakdown of (-)-secologanin.
1900994	(-)-secologanin biosynthetic process	P	The chemical reactions and pathways resulting in the formation of (-)-secologanin.
1900995	ubiquinone-6 binding	F	Interacting selectively and non-covalently with ubiquinone-6. Ubiquinone-6 is a ubiquinone compound having a (2E,6E,10E,14E,18E)-3,7,11,15,19,23-hexamethyltetracosa-2,6,10,14,18,22-hexaen-1-yl substituent at position 2.
1900996	benzene catabolic process	P	The chemical reactions and pathways resulting in the breakdown of benzene.
1900997	benzene biosynthetic process	P	The chemical reactions and pathways resulting in the formation of benzene.
1900998	nitrobenzene catabolic process	P	The chemical reactions and pathways resulting in the breakdown of nitrobenzene.
1900999	nitrobenzene biosynthetic process	P	The chemical reactions and pathways resulting in the formation of nitrobenzene.
1901000	regulation of response to salt stress	P	Any process that modulates the frequency, rate or extent of response to salt stress.
1901001	negative regulation of response to salt stress	P	Any process that stops, prevents or reduces the frequency, rate or extent of response to salt stress.
1901002	positive regulation of response to salt stress	P	Any process that activates or increases the frequency, rate or extent of response to salt stress.
1901003	negative regulation of fermentation	P	Any process that stops, prevents or reduces the frequency, rate or extent of fermentation.
1901004	ubiquinone-6 metabolic process	P	The chemical reactions and pathways involving ubiquinone-6. Ubiquinone-6 is a ubiquinone compound having a (2E,6E,10E,14E,18E)-3,7,11,15,19,23-hexamethyltetracosa-2,6,10,14,18,22-hexaen-1-yl substituent at position 2.
1901005	ubiquinone-6 catabolic process	P	The chemical reactions and pathways resulting in the breakdown of ubiquinone-6.
1901006	ubiquinone-6 biosynthetic process	P	The chemical reactions and pathways resulting in the formation of ubiquinone-6.
1901007	(S)-scoulerine metabolic process	P	The chemical reactions and pathways involving (S)-scoulerine.
1901008	(S)-scoulerine catabolic process	P	The chemical reactions and pathways resulting in the breakdown of (S)-scoulerine.
1901009	(S)-scoulerine biosynthetic process	P	The chemical reactions and pathways resulting in the formation of (S)-scoulerine.
1901010	(S)-reticuline metabolic process	P	The chemical reactions and pathways involving (S)-reticuline.
1901011	(S)-reticuline catabolic process	P	The chemical reactions and pathways resulting in the breakdown of (S)-reticuline.
1901012	(S)-reticuline biosynthetic process	P	The chemical reactions and pathways resulting in the formation of (S)-reticuline.
1901013	3alpha(S)-strictosidine metabolic process	P	The chemical reactions and pathways involving 3alpha(S)-strictosidine.
1901014	3alpha(S)-strictosidine catabolic process	P	The chemical reactions and pathways resulting in the breakdown of 3alpha(S)-strictosidine.
1901015	3alpha(S)-strictosidine biosynthetic process	P	The chemical reactions and pathways resulting in the formation of 3alpha(S)-strictosidine.
1901016	regulation of potassium ion transmembrane transporter activity	P	Any process that modulates the frequency, rate or extent of potassium ion transmembrane transporter activity.
1901017	negative regulation of potassium ion transmembrane transporter activity	P	Any process that stops, prevents or reduces the frequency, rate or extent of potassium ion transmembrane transporter activity.
1901018	positive regulation of potassium ion transmembrane transporter activity	P	Any process that activates or increases the frequency, rate or extent of potassium ion transmembrane transporter activity.
1901019	regulation of calcium ion transmembrane transporter activity	P	Any process that modulates the frequency, rate or extent of calcium ion transmembrane transporter activity.
1901020	negative regulation of calcium ion transmembrane transporter activity	P	Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion transmembrane transporter activity.
1901021	positive regulation of calcium ion transmembrane transporter activity	P	Any process that activates or increases the frequency, rate or extent of calcium ion transmembrane transporter activity.
1901022	4-hydroxyphenylacetate metabolic process	P	The chemical reactions and pathways involving 4-hydroxyphenylacetate.
1901023	4-hydroxyphenylacetate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of 4-hydroxyphenylacetate.
1901024	4-hydroxyphenylacetate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of 4-hydroxyphenylacetate.
1901025	ripoptosome assembly involved in extrinsic apoptotic signaling pathway	P	The aggregation, arrangement and bonding together of ripoptosome components leading to apoptosis via the extrinsic apoptotic signaling pathway.
1901026	ripoptosome assembly involved in necroptotic process	P	The aggregation, arrangement and bonding together of ripoptosome components leading to a necroptotic process.
1901027	dextrin catabolic process	P	The chemical reactions and pathways resulting in the breakdown of dextrin.
1901028	regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway	P	Any process that modulates the frequency, rate or extent of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway.
1901029	negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway	P	Any process that stops, prevents or reduces the frequency, rate or extent of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway.
1901030	positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway	P	Any process that activates or increases the frequency, rate or extent of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway.
1901031	regulation of response to reactive oxygen species	P	Any process that modulates the frequency, rate or extent of response to reactive oxygen species.
1901032	negative regulation of response to reactive oxygen species	P	Any process that stops, prevents or reduces the frequency, rate or extent of response to reactive oxygen species.
1901033	positive regulation of response to reactive oxygen species	P	Any process that activates or increases the frequency, rate or extent of response to reactive oxygen species.
1901034	regulation of L-glutamine import	P	Any process that modulates the frequency, rate or extent of L-glutamine import.
1901035	negative regulation of L-glutamine import	P	Any process that stops, prevents or reduces the frequency, rate or extent of L-glutamine import.
1901036	positive regulation of L-glutamine import	P	Any process that activates or increases the frequency, rate or extent of L-glutamine import.
1901038	cyanidin 3-O-glucoside metabolic process	P	The chemical reactions and pathways involving cyanidin 3-O-beta-D-glucoside.
1901039	regulation of peptide antigen transport	P	Any process that modulates the frequency, rate or extent of peptide antigen transport.
1901040	negative regulation of peptide antigen transport	P	Any process that stops, prevents or reduces the frequency, rate or extent of peptide antigen transport.
1901041	positive regulation of peptide antigen transport	P	Any process that activates or increases the frequency, rate or extent of peptide antigen transport.
1901042	positive regulation of L-arginine import	P	Any process that activates or increases the frequency, rate or extent of L-arginine import.
1901044	protein polyubiquitination involved in nucleus-associated proteasomal ubiquitin-dependent protein catabolic process	P	Any protein polyubiquitination that is involved in nucleus-associated proteasomal ubiquitin-dependent protein catabolic process.
1901045	negative regulation of oviposition	P	Any process that stops, prevents or reduces the frequency, rate or extent of oviposition.
1901046	positive regulation of oviposition	P	Any process that activates or increases the frequency, rate or extent of oviposition.
1901047	insulin receptor signaling pathway involved in determination of adult lifespan	P	The series of molecular signals generated as a consequence of the insulin receptor binding to insulin that controls viability and duration in the adult phase of the life-cycle.
1901048	transforming growth factor beta receptor signaling pathway involved in regulation of multicellular organism growth	P	A series of molecular signals initiated by the binding of an extracellular ligand to a transforming growth factor beta receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription, that modulates the frequency, rate or extent of growth of the body of an organism so that it reaches its usual body size.
1901049	atropine metabolic process	P	The chemical reactions and pathways involving atropine.
1901050	atropine catabolic process	P	The chemical reactions and pathways resulting in the breakdown of atropine.
1901051	atropine biosynthetic process	P	The chemical reactions and pathways resulting in the formation of atropine.
1901052	sarcosine metabolic process	P	The chemical reactions and pathways involving sarcosine.
1901053	sarcosine catabolic process	P	The chemical reactions and pathways resulting in the breakdown of sarcosine.
1901054	sarcosine biosynthetic process	P	The chemical reactions and pathways resulting in the formation of sarcosine.
1901055	trimethylenediamine metabolic process	P	The chemical reactions and pathways involving trimethylenediamine.
1901056	trimethylenediamine catabolic process	P	The chemical reactions and pathways resulting in the breakdown of trimethylenediamine.
1901057	trimethylenediamine biosynthetic process	P	The chemical reactions and pathways resulting in the formation of trimethylenediamine.
1901058	p-hydroxyphenyl lignin metabolic process	P	The chemical reactions and pathways involving p-hydroxyphenyl lignin.
1901059	p-hydroxyphenyl lignin catabolic process	P	The chemical reactions and pathways resulting in the breakdown of p-hydroxyphenyl lignin.
1901060	p-hydroxyphenyl lignin biosynthetic process	P	The chemical reactions and pathways resulting in the formation of p-hydroxyphenyl lignin.
1901061	guaiacyl lignin metabolic process	P	The chemical reactions and pathways involving guaiacyl lignin.
1901062	guaiacyl lignin catabolic process	P	The chemical reactions and pathways resulting in the breakdown of guaiacyl lignin.
1901063	guaiacyl lignin biosynthetic process	P	The chemical reactions and pathways resulting in the formation of guaiacyl lignin.
1901064	syringal lignin metabolic process	P	The chemical reactions and pathways involving syringal lignin.
1901065	syringal lignin catabolic process	P	The chemical reactions and pathways resulting in the breakdown of syringal lignin.
1901066	syringal lignin biosynthetic process	P	The chemical reactions and pathways resulting in the formation of syringal lignin.
1901067	ferulate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of ferulate.
1901068	guanosine-containing compound metabolic process	P	The chemical reactions and pathways involving guanosine-containing compounds (guanosines).
1901069	guanosine-containing compound catabolic process	P	The chemical reactions and pathways resulting in the breakdown of guanosine-containing compounds (guanosines).
1901070	guanosine-containing compound biosynthetic process	P	The chemical reactions and pathways resulting in the formation of guanosine-containing compounds (guanosines).
1901071	glucosamine-containing compound metabolic process	P	The chemical reactions and pathways involving glucosamine-containing compounds (glucosamines).
1901072	glucosamine-containing compound catabolic process	P	The chemical reactions and pathways resulting in the breakdown of glucosamine-containing compounds (glucosamines).
1901073	glucosamine-containing compound biosynthetic process	P	The chemical reactions and pathways resulting in the formation of glucosamine-containing compounds (glucosamines).
1901074	regulation of engulfment of apoptotic cell	P	Any process that modulates the frequency, rate or extent of engulfment of apoptotic cell.
1901075	negative regulation of engulfment of apoptotic cell	P	Any process that stops, prevents or reduces the frequency, rate or extent of engulfment of apoptotic cell.
1901076	positive regulation of engulfment of apoptotic cell	P	Any process that activates or increases the frequency, rate or extent of engulfment of apoptotic cell.
1901077	regulation of relaxation of muscle	P	Any process that modulates the frequency, rate or extent of relaxation of muscle.
1901078	negative regulation of relaxation of muscle	P	Any process that stops, prevents or reduces the frequency, rate or extent of relaxation of muscle.
1901079	positive regulation of relaxation of muscle	P	Any process that activates or increases the frequency, rate or extent of relaxation of muscle.
1901080	regulation of relaxation of smooth muscle	P	Any process that modulates the frequency, rate or extent of relaxation of smooth muscle.
1901081	negative regulation of relaxation of smooth muscle	P	Any process that stops, prevents or reduces the frequency, rate or extent of relaxation of smooth muscle.
1901082	positive regulation of relaxation of smooth muscle	P	Any process that activates or increases the frequency, rate or extent of relaxation of smooth muscle.
1901083	pyrrolizidine alkaloid metabolic process	P	The chemical reactions and pathways involving pyrrolizidine alkaloid.
1901084	pyrrolizidine alkaloid catabolic process	P	The chemical reactions and pathways resulting in the breakdown of pyrrolizidine alkaloid.
1901085	pyrrolizidine alkaloid biosynthetic process	P	The chemical reactions and pathways resulting in the formation of pyrrolizidine alkaloid.
1901086	benzylpenicillin metabolic process	P	The chemical reactions and pathways involving benzylpenicillin.
1901087	benzylpenicillin catabolic process	P	The chemical reactions and pathways resulting in the breakdown of benzylpenicillin.
1901088	benzylpenicillin biosynthetic process	P	The chemical reactions and pathways resulting in the formation of benzylpenicillin.
1901089	acetate ester metabolic process involved in fermentation	P	Any acetate ester metabolic process that is involved in fermentation.
1901090	regulation of protein tetramerization	P	Any process that modulates the frequency, rate or extent of protein tetramerization.
1901091	negative regulation of protein tetramerization	P	Any process that stops, prevents or reduces the frequency, rate or extent of protein tetramerization.
1901092	positive regulation of protein tetramerization	P	Any process that activates or increases the frequency, rate or extent of protein tetramerization.
1901093	regulation of protein homotetramerization	P	Any process that modulates the frequency, rate or extent of protein homotetramerization.
1901094	negative regulation of protein homotetramerization	P	Any process that stops, prevents or reduces the frequency, rate or extent of protein homotetramerization.
1901095	positive regulation of protein homotetramerization	P	Any process that activates or increases the frequency, rate or extent of protein homotetramerization.
1901096	regulation of autophagosome maturation	P	Any process that modulates the frequency, rate or extent of autophagosome maturation.
1901097	negative regulation of autophagosome maturation	P	Any process that stops, prevents or reduces the frequency, rate or extent of autophagosome maturation.
1901098	positive regulation of autophagosome maturation	P	Any process that activates or increases the frequency, rate or extent of autophagosome maturation.
1901099	negative regulation of signal transduction in absence of ligand	P	Any process that stops, prevents or reduces the frequency, rate or extent of signal transduction in absence of ligand.
1901101	gramicidin S metabolic process	P	The chemical reactions and pathways involving gramicidin S.
1901102	gramicidin S catabolic process	P	The chemical reactions and pathways resulting in the breakdown of gramicidin S.
1901103	gramicidin S biosynthetic process	P	The chemical reactions and pathways resulting in the formation of gramicidin S.
1901104	tetracenomycin C metabolic process	P	The chemical reactions and pathways involving tetracenomycin C.
1901105	tetracenomycin C catabolic process	P	The chemical reactions and pathways resulting in the breakdown of tetracenomycin C.
1901106	tetracenomycin C biosynthetic process	P	The chemical reactions and pathways resulting in the formation of tetracenomycin C.
1901107	granaticin metabolic process	P	The chemical reactions and pathways involving granaticin.
1901108	granaticin catabolic process	P	The chemical reactions and pathways resulting in the breakdown of granaticin.
1901109	granaticin biosynthetic process	P	The chemical reactions and pathways resulting in the formation of granaticin.
1901110	actinorhodin metabolic process	P	The chemical reactions and pathways involving actinorhodin.
1901111	actinorhodin catabolic process	P	The chemical reactions and pathways resulting in the breakdown of actinorhodin.
1901112	actinorhodin biosynthetic process	P	The chemical reactions and pathways resulting in the formation of actinorhodin.
1901113	erythromycin metabolic process	P	The chemical reactions and pathways involving erythromycin.
1901114	erythromycin catabolic process	P	The chemical reactions and pathways resulting in the breakdown of erythromycin.
1901115	erythromycin biosynthetic process	P	The chemical reactions and pathways resulting in the formation of erythromycin.
1901116	cephamycin C metabolic process	P	The chemical reactions and pathways involving cephamycin C.
1901117	cephamycin C catabolic process	P	The chemical reactions and pathways resulting in the breakdown of cephamycin C.
1901118	cephamycin C biosynthetic process	P	The chemical reactions and pathways resulting in the formation of cephamycin C.
1901119	tobramycin metabolic process	P	The chemical reactions and pathways involving tobramycin.
1901120	tobramycin catabolic process	P	The chemical reactions and pathways resulting in the breakdown of tobramycin.
1901121	tobramycin biosynthetic process	P	The chemical reactions and pathways resulting in the formation of tobramycin.
1901122	bacitracin A metabolic process	P	The chemical reactions and pathways involving bacitracin A.
1901123	bacitracin A catabolic process	P	The chemical reactions and pathways resulting in the breakdown of bacitracin A.
1901124	bacitracin A biosynthetic process	P	The chemical reactions and pathways resulting in the formation of bacitracin A.
1901125	candicidin metabolic process	P	The chemical reactions and pathways involving candicidin.
1901126	candicidin catabolic process	P	The chemical reactions and pathways resulting in the breakdown of candicidin.
1901127	candicidin biosynthetic process	P	The chemical reactions and pathways resulting in the formation of candicidin.
1901128	gentamycin metabolic process	P	The chemical reactions and pathways involving gentamycin.
1901129	gentamycin catabolic process	P	The chemical reactions and pathways resulting in the breakdown of gentamycin.
1901130	gentamycin biosynthetic process	P	The chemical reactions and pathways resulting in the formation of gentamycin.
1901131	kanamycin metabolic process	P	The chemical reactions and pathways involving kanamycin.
1901132	kanamycin catabolic process	P	The chemical reactions and pathways resulting in the breakdown of kanamycin.
1901133	kanamycin biosynthetic process	P	The chemical reactions and pathways resulting in the formation of kanamycin.
1901134	negative regulation of coflocculation via protein-carbohydrate interaction	P	Any process that stops, prevents or reduces the frequency, rate or extent of coflocculation via protein-carbohydrate interaction.
1901135	carbohydrate derivative metabolic process	P	The chemical reactions and pathways involving carbohydrate derivative.
1901136	carbohydrate derivative catabolic process	P	The chemical reactions and pathways resulting in the breakdown of carbohydrate derivative.
1901137	carbohydrate derivative biosynthetic process	P	The chemical reactions and pathways resulting in the formation of carbohydrate derivative.
1901140	p-coumaryl alcohol transport	P	The directed movement of a p-coumaryl alcohol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
1901141	regulation of lignin biosynthetic process	P	Any process that modulates the frequency, rate or extent of lignin biosynthetic process.
1901142	insulin metabolic process	P	The chemical reactions and pathways involving insulin.
1901143	insulin catabolic process	P	The chemical reactions and pathways resulting in the breakdown of insulin.
1901145	mesenchymal cell apoptotic process involved in nephron morphogenesis	P	Any mesenchymal cell apoptotic process that is involved in nephron morphogenesis.
1901146	mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis	P	Any mesenchymal cell apoptotic process that is involved in mesonephric nephron morphogenesis.
1901147	mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis	P	Any mesenchymal cell apoptotic process that is involved in metanephric nephron morphogenesis.
1901148	gene expression involved in extracellular matrix organization	P	Any gene expression that is involved in extracellular matrix organization. Gene expression includes both transcription to produce an RNA transcript, and the translation of that mRNA into protein. Protein maturation is included in gene expression when required to form an active form of a product from an inactive precursor form.
1901149	salicylic acid binding	F	Interacting selectively and non-covalently with salicylic acid.
1901150	vistamycin metabolic process	P	The chemical reactions and pathways involving vistamycin.
1901151	vistamycin catabolic process	P	The chemical reactions and pathways resulting in the breakdown of vistamycin.
1901152	vistamycin biosynthetic process	P	The chemical reactions and pathways resulting in the formation of vistamycin.
1901153	paromomycin metabolic process	P	The chemical reactions and pathways involving paromomycin.
1901154	paromomycin catabolic process	P	The chemical reactions and pathways resulting in the breakdown of paromomycin.
1901155	paromomycin biosynthetic process	P	The chemical reactions and pathways resulting in the formation of paromomycin.
1901156	neomycin metabolic process	P	The chemical reactions and pathways involving neomycin.
1901157	neomycin catabolic process	P	The chemical reactions and pathways resulting in the breakdown of neomycin.
1901158	neomycin biosynthetic process	P	The chemical reactions and pathways resulting in the formation of neomycin.
1901159	xylulose 5-phosphate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of xylulose 5-phosphate.
1901160	primary amino compound metabolic process	P	The chemical reactions and pathways involving primary amino compound.
1901161	primary amino compound catabolic process	P	The chemical reactions and pathways resulting in the breakdown of primary amino compound.
1901162	primary amino compound biosynthetic process	P	The chemical reactions and pathways resulting in the formation of primary amino compound.
1901163	regulation of trophoblast cell migration	P	Any process that modulates the frequency, rate or extent of trophoblast cell migration.
1901164	negative regulation of trophoblast cell migration	P	Any process that stops, prevents or reduces the frequency, rate or extent of trophoblast cell migration.
1901165	positive regulation of trophoblast cell migration	P	Any process that activates or increases the frequency, rate or extent of trophoblast cell migration.
1901166	neural crest cell migration involved in autonomic nervous system development	P	Any neural crest cell migration that is involved in autonomic nervous system development.
1901167	3-chlorocatechol metabolic process	P	The chemical reactions and pathways involving 3-chlorocatechol.
1901168	3-chlorocatechol catabolic process	P	The chemical reactions and pathways resulting in the breakdown of 3-chlorocatechol.
1901169	3-chlorocatechol biosynthetic process	P	The chemical reactions and pathways resulting in the formation of 3-chlorocatechol.
1901170	naphthalene catabolic process	P	The chemical reactions and pathways resulting in the breakdown of naphthalene.
1901171	naphthalene biosynthetic process	P	The chemical reactions and pathways resulting in the formation of naphthalene.
1901172	phytoene metabolic process	P	The chemical reactions and pathways involving phytoene.
1901173	phytoene catabolic process	P	The chemical reactions and pathways resulting in the breakdown of phytoene.
1901174	phytoene biosynthetic process	P	The chemical reactions and pathways resulting in the formation of phytoene.
1901175	lycopene metabolic process	P	The chemical reactions and pathways involving lycopene.
1901176	lycopene catabolic process	P	The chemical reactions and pathways resulting in the breakdown of lycopene.
1901177	lycopene biosynthetic process	P	The chemical reactions and pathways resulting in the formation of lycopene.
1901178	spheroidene metabolic process	P	The chemical reactions and pathways involving spheroidene.
1901179	spheroidene catabolic process	P	The chemical reactions and pathways resulting in the breakdown of spheroidene.
1901180	spheroidene biosynthetic process	P	The chemical reactions and pathways resulting in the formation of spheroidene.
1901181	negative regulation of cellular response to caffeine	P	Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to caffeine.
1901182	regulation of camalexin biosynthetic process	P	Any process that modulates the frequency, rate or extent of camalexin biosynthetic process.
1901183	positive regulation of camalexin biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of camalexin biosynthetic process.
1901184	regulation of ERBB signaling pathway	P	Any process that modulates the frequency, rate or extent of ERBB signaling pathway.
1901185	negative regulation of ERBB signaling pathway	P	Any process that stops, prevents or reduces the frequency, rate or extent of ERBB signaling pathway.
1901186	positive regulation of ERBB signaling pathway	P	Any process that activates or increases the frequency, rate or extent of ERBB signaling pathway.
1901187	regulation of ephrin receptor signaling pathway	P	Any process that modulates the frequency, rate or extent of ephrin receptor signaling pathway.
1901188	negative regulation of ephrin receptor signaling pathway	P	Any process that stops, prevents or reduces the frequency, rate or extent of ephrin receptor signaling pathway.
1901189	positive regulation of ephrin receptor signaling pathway	P	Any process that activates or increases the frequency, rate or extent of ephrin receptor signaling pathway.
1901190	regulation of formation of translation initiation ternary complex	P	Any process that modulates the frequency, rate or extent of formation of translation initiation ternary complex.
1901191	negative regulation of formation of translation initiation ternary complex	P	Any process that stops, prevents or reduces the frequency, rate or extent of formation of translation initiation ternary complex.
1901192	positive regulation of formation of translation initiation ternary complex	P	Any process that activates or increases the frequency, rate or extent of formation of translation initiation ternary complex.
1901193	regulation of formation of translation preinitiation complex	P	Any process that modulates the frequency, rate or extent of formation of translation preinitiation complex.
1901194	negative regulation of formation of translation preinitiation complex	P	Any process that stops, prevents or reduces the frequency, rate or extent of formation of translation preinitiation complex.
1901195	positive regulation of formation of translation preinitiation complex	P	Any process that activates or increases the frequency, rate or extent of formation of translation preinitiation complex.
1901196	positive regulation of calcium-mediated signaling involved in cellular response to salt stress	P	Any positive regulation of calcium-mediated signaling that is involved in cellular response to salt stress.
1901197	positive regulation of calcium-mediated signaling involved in cellular response to calcium ion	P	Any positive regulation of calcium-mediated signaling that is involved in cellular response to calcium ion.
1901198	positive regulation of calcium ion transport into cytosol involved in cellular response to calcium ion	P	Any positive regulation of calcium ion transport into cytosol that is involved in cellular response to calcium ion.
1901199	positive regulation of calcium ion transport into cytosol involved in cellular response to salt stress	P	Any positive regulation of calcium ion transport into cytosol that is involved in cellular response to salt stress.
1901200	negative regulation of calcium ion transport into cytosol involved in cellular response to salt stress	P	Any negative regulation of calcium ion transport into cytosol that is involved in cellular response to salt stress.
1901201	regulation of extracellular matrix assembly	P	Any process that modulates the frequency, rate or extent of extracellular matrix assembly.
1901202	negative regulation of extracellular matrix assembly	P	Any process that stops, prevents or reduces the frequency, rate or extent of extracellular matrix assembly.
1901203	positive regulation of extracellular matrix assembly	P	Any process that activates or increases the frequency, rate or extent of extracellular matrix assembly.
1901204	regulation of adrenergic receptor signaling pathway involved in heart process	P	Any process that modulates the frequency, rate or extent of a cardiac adrenergic receptor signaling pathway.
1901205	negative regulation of adrenergic receptor signaling pathway involved in heart process	P	Any process that stops, prevents or reduces the frequency, rate or extent of a cardiac adrenergic receptor signaling pathway.
1901206	positive regulation of adrenergic receptor signaling pathway involved in heart process	P	Any process that activates or increases the frequency, rate or extent of a cardiac adrenergic receptor signaling pathway.
1901207	regulation of heart looping	P	Any process that modulates the frequency, rate or extent of heart looping.
1901208	negative regulation of heart looping	P	Any process that stops, prevents or reduces the frequency, rate or extent of heart looping.
1901209	positive regulation of heart looping	P	Any process that activates or increases the frequency, rate or extent of heart looping.
1901210	regulation of cardiac chamber formation	P	Any process that modulates the frequency, rate or extent of cardiac chamber formation.
1901211	negative regulation of cardiac chamber formation	P	Any process that stops, prevents or reduces the frequency, rate or extent of cardiac chamber formation.
1901212	positive regulation of cardiac chamber formation	P	Any process that activates or increases the frequency, rate or extent of cardiac chamber formation.
1901213	regulation of transcription from RNA polymerase II promoter involved in heart development	P	Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter that contributes to the development of the heart over time.
1901214	regulation of neuron death	P	Any process that modulates the frequency, rate or extent of neuron death.
1901215	negative regulation of neuron death	P	Any process that stops, prevents or reduces the frequency, rate or extent of neuron death.
1901216	positive regulation of neuron death	P	Any process that activates or increases the frequency, rate or extent of neuron death.
1901217	regulation of holin activity	P	Any process that modulates the frequency, rate or extent of holin activity.
1901218	negative regulation of holin activity	P	Any process that stops, prevents or reduces the frequency, rate or extent of holin activity.
1901219	regulation of cardiac chamber morphogenesis	P	Any process that modulates the frequency, rate or extent of cardiac chamber morphogenesis.
1901220	negative regulation of cardiac chamber morphogenesis	P	Any process that stops, prevents or reduces the frequency, rate or extent of cardiac chamber morphogenesis.
1901221	positive regulation of cardiac chamber morphogenesis	P	Any process that activates or increases the frequency, rate or extent of cardiac chamber morphogenesis.
1901222	regulation of NIK/NF-kappaB signaling	P	Any process that modulates the frequency, rate or extent of NIK/NF-kappaB signaling.
1901223	negative regulation of NIK/NF-kappaB signaling	P	Any process that stops, prevents or reduces the frequency, rate or extent of NIK/NF-kappaB signaling.
1901224	positive regulation of NIK/NF-kappaB signaling	P	Any process that activates or increases the frequency, rate or extent of NIK/NF-kappaB signaling.
1901227	negative regulation of transcription from RNA polymerase II promoter involved in heart development	P	Any negative regulation of transcription from RNA polymerase II promoter that is involved in heart development.
1901228	positive regulation of transcription from RNA polymerase II promoter involved in heart development	P	Any positive regulation of transcription from RNA polymerase II promoter that is involved in heart development.
1901229	regulation of non-canonical Wnt signaling pathway via JNK cascade	P	Any process that modulates the frequency, rate or extent of non-canonical Wnt signaling pathway via JNK cascade.
1901230	negative regulation of non-canonical Wnt signaling pathway via JNK cascade	P	Any process that stops, prevents or reduces the frequency, rate or extent of non-canonical Wnt signaling pathway via JNK cascade.
1901231	positive regulation of non-canonical Wnt signaling pathway via JNK cascade	P	Any process that activates or increases the frequency, rate or extent of non-canonical Wnt signaling pathway via JNK cascade.
1901232	regulation of convergent extension involved in axis elongation	P	Any process that modulates the frequency, rate or extent of convergent extension involved in axis elongation.
1901233	negative regulation of convergent extension involved in axis elongation	P	Any process that stops, prevents or reduces the frequency, rate or extent of convergent extension involved in axis elongation.
1901234	positive regulation of convergent extension involved in axis elongation	P	Any process that activates or increases the frequency, rate or extent of convergent extension involved in axis elongation.
1901235	(R)-carnitine transmembrane transporter activity	F	Enables the transfer of (R)-carnitine from one side of the membrane to the other.
1901236	4-(trimethylammonio)butanoate transmembrane transporter activity	F	Enables the transfer of 4-(trimethylammonio)butanoate from one side of the membrane to the other.
1901237	tungstate transmembrane transporter activity	F	Enables the transfer of tungstate from one side of the membrane to the other.
1901238	ATPase-coupled tungstate transmembrane transporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + tungstate(in) = ADP + phosphate + tungstate(out).
1901239	malonate(1-) transmembrane transporter activity	F	Enables the transfer of malonate(1-) from one side of the membrane to the other.
1901241	4-hydroxyphenylacetate transmembrane transporter activity	F	Enables the transfer of 4-hydroxyphenylacetate from one side of the membrane to the other.
1901242	ATPase-coupled doxorubicin transmembrane transporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + doxorubicin(in) = ADP + phosphate + doxorubicin(out).
1901243	ATPase-coupled methionine transmembrane transporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + methionine(in) = ADP + phosphate + methionine(out).
1901244	positive regulation of transcription from RNA polymerase II promoter involved in defense response to fungus	P	Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter to protect the cell or organism in response to the presence of a fungus.
1901245	positive regulation of toll-like receptor 9 signaling pathway by B cell receptor internalization	P	The movement of a B cell receptor (BCR) from the plasma membrane to the inside of the cell, which results in positive regulation of toll-like receptor 9 (TLR9) signaling. For example, internalized BCR signals to recruit TLR9 from multiple small endosomes to large autophagosome-like compartments to enhance TLR9 signaling.
1901246	regulation of lung ciliated cell differentiation	P	Any process that modulates the frequency, rate or extent of lung ciliated cell differentiation.
1901247	negative regulation of lung ciliated cell differentiation	P	Any process that stops, prevents or reduces the frequency, rate or extent of lung ciliated cell differentiation.
1901248	positive regulation of lung ciliated cell differentiation	P	Any process that activates or increases the frequency, rate or extent of lung ciliated cell differentiation.
1901249	regulation of lung goblet cell differentiation	P	Any process that modulates the frequency, rate or extent of lung goblet cell differentiation.
1901250	negative regulation of lung goblet cell differentiation	P	Any process that stops, prevents or reduces the frequency, rate or extent of lung goblet cell differentiation.
1901251	positive regulation of lung goblet cell differentiation	P	Any process that activates or increases the frequency, rate or extent of lung goblet cell differentiation.
1901252	regulation of intracellular transport of viral material	P	Any process that modulates the frequency, rate or extent of egress of virus within host cell.
1901253	negative regulation of intracellular transport of viral material	P	Any process that stops, prevents or reduces the frequency, rate or extent of intracellular transport of viral material.
1901254	positive regulation of intracellular transport of viral material	P	Any process that activates or increases the frequency, rate or extent of intracellular transport of viral material.
1901255	nucleotide-excision repair involved in interstrand cross-link repair	P	Any nucleotide-excision repair that is involved in interstrand cross-link repair.
1901256	regulation of macrophage colony-stimulating factor production	P	Any process that modulates the frequency, rate or extent of macrophage colony-stimulating factor production.
1901257	negative regulation of macrophage colony-stimulating factor production	P	Any process that stops, prevents or reduces the frequency, rate or extent of macrophage colony-stimulating factor production.
1901258	positive regulation of macrophage colony-stimulating factor production	P	Any process that activates or increases the frequency, rate or extent of macrophage colony-stimulating factor production.
1901259	chloroplast rRNA processing	P	Any rRNA processing that takes place in chloroplast.
1901260	peptidyl-lysine hydroxylation involved in bacterial-type EF-P lysine modification	P	Any peptidyl-lysine hydroxylation that is involved in bacterial-type EF-P lysine modification.
1901261	regulation of sorocarp spore cell differentiation	P	Any process that modulates the frequency, rate or extent of sorocarp spore cell differentiation.
1901262	negative regulation of sorocarp spore cell differentiation	P	Any process that stops, prevents or reduces the frequency, rate or extent of sorocarp spore cell differentiation.
1901263	positive regulation of sorocarp spore cell differentiation	P	Any process that activates or increases the frequency, rate or extent of sorocarp spore cell differentiation.
1901264	carbohydrate derivative transport	P	The directed movement of a carbohydrate derivative into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
1901265	nucleoside phosphate binding	F	Interacting selectively and non-covalently with nucleoside phosphate.
1901266	cephalosporin C metabolic process	P	The chemical reactions and pathways involving cephalosporin C.
1901267	cephalosporin C catabolic process	P	The chemical reactions and pathways resulting in the breakdown of cephalosporin C.
1901268	cephalosporin C biosynthetic process	P	The chemical reactions and pathways resulting in the formation of cephalosporin C.
1901269	lipooligosaccharide metabolic process	P	The chemical reactions and pathways involving lipooligosaccharide.
1901270	lipooligosaccharide catabolic process	P	The chemical reactions and pathways resulting in the breakdown of lipooligosaccharide.
1901271	lipooligosaccharide biosynthetic process	P	The chemical reactions and pathways resulting in the formation of lipooligosaccharide.
1901272	2-dehydro-3-deoxy-D-gluconic acid metabolic process	P	The chemical reactions and pathways involving 2-dehydro-3-deoxy-D-gluconic acid.
1901273	2-dehydro-3-deoxy-D-gluconic acid catabolic process	P	The chemical reactions and pathways resulting in the breakdown of 2-dehydro-3-deoxy-D-gluconic acid.
1901274	2-dehydro-3-deoxy-D-gluconic acid biosynthetic process	P	The chemical reactions and pathways resulting in the formation of 2-dehydro-3-deoxy-D-gluconic acid.
1901275	tartrate metabolic process	P	The chemical reactions and pathways involving tartrate.
1901276	tartrate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of tartrate.
1901277	tartrate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of tartrate.
1901278	D-ribose 5-phosphate metabolic process	P	The chemical reactions and pathways involving D-ribose 5-phosphate.
1901279	D-ribose 5-phosphate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of D-ribose 5-phosphate.
1901280	D-ribose 5-phosphate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of D-ribose 5-phosphate.
1901281	fructoselysine catabolic process	P	The chemical reactions and pathways resulting in the breakdown of fructoselysine.
1901282	fructoselysine biosynthetic process	P	The chemical reactions and pathways resulting in the formation of fructoselysine.
1901283	5,6,7,8-tetrahydromethanopterin metabolic process	P	The chemical reactions and pathways involving 5,6,7,8-tetrahydromethanopterin.
1901284	5,6,7,8-tetrahydromethanopterin catabolic process	P	The chemical reactions and pathways resulting in the breakdown of 5,6,7,8-tetrahydromethanopterin.
1901285	5,6,7,8-tetrahydromethanopterin biosynthetic process	P	The chemical reactions and pathways resulting in the formation of 5,6,7,8-tetrahydromethanopterin.
1901286	iron-sulfur-molybdenum cofactor metabolic process	P	The chemical reactions and pathways involving iron-sulfur-molybdenum cofactor.
1901287	iron-sulfur-molybdenum cofactor catabolic process	P	The chemical reactions and pathways resulting in the breakdown of iron-sulfur-molybdenum cofactor.
1901288	iron-sulfur-molybdenum cofactor biosynthetic process	P	The chemical reactions and pathways resulting in the formation of iron-sulfur-molybdenum cofactor.
1901289	succinyl-CoA catabolic process	P	The chemical reactions and pathways resulting in the breakdown of succinyl-CoA.
1901290	succinyl-CoA biosynthetic process	P	The chemical reactions and pathways resulting in the formation of succinyl-CoA.
1901291	negative regulation of double-strand break repair via single-strand annealing	P	Any process that stops, prevents or reduces the frequency, rate or extent of double-strand break repair via single-strand annealing.
1901292	nucleoside phosphate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of a nucleoside phosphate.
1901293	nucleoside phosphate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of a nucleoside phosphate.
1901294	negative regulation of SREBP signaling pathway by negative regulation of DNA binding	P	Negative regulation of DNA binding that results in negative regulation of a SREBP signaling pathway.
1901295	regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment	P	Any process that modulates the frequency, rate or extent of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment.
1901296	negative regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment	P	Any process that stops, prevents or reduces the frequency, rate or extent of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment.
1901297	positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment	P	Any process that activates or increases the frequency, rate or extent of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment.
1901298	regulation of hydrogen peroxide-mediated programmed cell death	P	Any process that modulates the frequency, rate or extent of hydrogen peroxide-mediated programmed cell death.
1901299	negative regulation of hydrogen peroxide-mediated programmed cell death	P	Any process that stops, prevents or reduces the frequency, rate or extent of hydrogen peroxide-mediated programmed cell death.
1901300	positive regulation of hydrogen peroxide-mediated programmed cell death	P	Any process that activates or increases the frequency, rate or extent of hydrogen peroxide-mediated programmed cell death.
1901301	regulation of cargo loading into COPII-coated vesicle	P	Any process that modulates the frequency, rate or extent of cargo loading into COPII-coated vesicle.
1901303	negative regulation of cargo loading into COPII-coated vesicle	P	Any process that stops, prevents or reduces the frequency, rate or extent of cargo loading into a COPII-coated vesicle.
1901304	regulation of spermidine biosynthetic process	P	Any process that modulates the frequency, rate or extent of spermidine biosynthetic process.
1901305	negative regulation of spermidine biosynthetic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of spermidine biosynthetic process.
1901307	positive regulation of spermidine biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of spermidine biosynthetic process.
1901308	regulation of sterol regulatory element binding protein cleavage	P	Any process that modulates the frequency, rate or extent of sterol regulatory element binding protein cleavage.
1901309	negative regulation of sterol regulatory element binding protein cleavage	P	Any process that stops, prevents or reduces the frequency, rate or extent of sterol regulatory element binding protein cleavage.
1901310	positive regulation of sterol regulatory element binding protein cleavage	P	Any process that activates or increases the frequency, rate or extent of sterol regulatory element binding protein cleavage.
1901314	regulation of histone H2A K63-linked ubiquitination	P	Any process that modulates the frequency, rate or extent of histone H2A K63-linked ubiquitination.
1901315	negative regulation of histone H2A K63-linked ubiquitination	P	Any process that stops, prevents or reduces the frequency, rate or extent of histone H2A K63-linked ubiquitination.
1901316	positive regulation of histone H2A K63-linked ubiquitination	P	Any process that activates or increases the frequency, rate or extent of histone H2A K63-linked ubiquitination.
1901317	regulation of flagellated sperm motility	P	Any process that modulates the frequency, rate or extent of flagellated sperm motility.
1901318	negative regulation of flagellated sperm motility	P	Any process that stops, prevents or reduces the frequency, rate or extent of flagellated sperm motility.
1901319	positive regulation of trehalose catabolic process	P	Any process that activates or increases the frequency, rate or extent of trehalose catabolic process.
1901320	negative regulation of heart induction	P	Any process that stops, prevents or reduces the frequency, rate or extent of heart induction.
1901321	positive regulation of heart induction	P	Any process that activates or increases the frequency, rate or extent of heart induction.
1901322	response to chloramphenicol	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chloramphenicol stimulus.
1901323	response to erythromycin	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an erythromycin stimulus.
1901324	response to trichodermin	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a trichodermin stimulus.
1901325	response to antimycin A	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an antimycin A stimulus.
1901326	response to tetracycline	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tetracycline stimulus.
1901327	response to tacrolimus	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tacrolimus stimulus.
1901328	response to cytochalasin B	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytochalasin B stimulus.
1901329	regulation of odontoblast differentiation	P	Any process that modulates the frequency, rate or extent of odontoblast differentiation.
1901330	negative regulation of odontoblast differentiation	P	Any process that stops, prevents or reduces the frequency, rate or extent of odontoblast differentiation.
1901331	positive regulation of odontoblast differentiation	P	Any process that activates or increases the frequency, rate or extent of odontoblast differentiation.
1901332	negative regulation of lateral root development	P	Any process that stops, prevents or reduces the frequency, rate or extent of lateral root development.
1901333	positive regulation of lateral root development	P	Any process that activates or increases the frequency, rate or extent of lateral root development.
1901334	lactone metabolic process	P	The chemical reactions and pathways involving lactone.
1901335	lactone catabolic process	P	The chemical reactions and pathways resulting in the breakdown of lactone.
1901336	lactone biosynthetic process	P	The chemical reactions and pathways resulting in the formation of lactone.
1901337	thioester transport	P	The directed movement of a thioester into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
1901338	catecholamine binding	F	Interacting selectively and non-covalently with catecholamine.
1901339	regulation of store-operated calcium channel activity	P	Any process that modulates the frequency, rate or extent of store-operated calcium channel activity.
1901340	negative regulation of store-operated calcium channel activity	P	Any process that stops, prevents or reduces the frequency, rate or extent of store-operated calcium channel activity.
1901341	positive regulation of store-operated calcium channel activity	P	Any process that activates or increases the frequency, rate or extent of store-operated calcium channel activity.
1901342	regulation of vasculature development	P	Any process that modulates the frequency, rate or extent of vasculature development.
1901343	negative regulation of vasculature development	P	Any process that stops, prevents or reduces the frequency, rate or extent of vasculature development.
1901344	response to leptomycin B	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a leptomycin B stimulus.
1901345	response to L-thialysine	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-thialysine stimulus.
1901346	negative regulation of vasculature development involved in avascular cornea development in camera-type eye	P	Any negative regulation of vasculature development that is involved in developing an avascular cornea of a camera-type eye.
1901347	negative regulation of secondary cell wall biogenesis	P	Any process that stops, prevents or reduces the frequency, rate or extent of secondary cell wall biogenesis.
1901348	positive regulation of secondary cell wall biogenesis	P	Any process that activates or increases the frequency, rate or extent of secondary cell wall biogenesis.
1901349	glucosinolate transport	P	The directed movement of a glucosinolate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
1901350	cell-cell signaling involved in cell-cell junction organization	P	Any cell-cell signaling that is involved in cell-cell junction organization.
1901351	regulation of phosphatidylglycerol biosynthetic process	P	Any process that modulates the frequency, rate or extent of phosphatidylglycerol biosynthetic process.
1901352	negative regulation of phosphatidylglycerol biosynthetic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of phosphatidylglycerol biosynthetic process.
1901353	positive regulation of phosphatidylglycerol biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of phosphatidylglycerol biosynthetic process.
1901354	response to L-canavanine	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-canavanine stimulus.
1901355	response to rapamycin	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a rapamycin stimulus.
1901356	beta-D-galactofuranose metabolic process	P	The chemical reactions and pathways involving beta-D-galactofuranose.
1901357	beta-D-galactofuranose catabolic process	P	The chemical reactions and pathways resulting in the breakdown of beta-D-galactofuranose.
1901358	beta-D-galactofuranose biosynthetic process	P	The chemical reactions and pathways resulting in the formation of beta-D-galactofuranose.
1901359	tungstate binding	F	Interacting selectively and non-covalently with tungstate.
1901360	organic cyclic compound metabolic process	P	The chemical reactions and pathways involving organic cyclic compound.
1901361	organic cyclic compound catabolic process	P	The chemical reactions and pathways resulting in the breakdown of organic cyclic compound.
1901362	organic cyclic compound biosynthetic process	P	The chemical reactions and pathways resulting in the formation of organic cyclic compound.
1901363	heterocyclic compound binding	F	Interacting selectively and non-covalently with heterocyclic compound.
1901364	funalenone metabolic process	P	The chemical reactions and pathways involving funalenone.
1901365	funalenone catabolic process	P	The chemical reactions and pathways resulting in the breakdown of funalenone.
1901366	funalenone biosynthetic process	P	The chemical reactions and pathways resulting in the formation of funalenone.
1901367	response to L-cysteine	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-cysteine stimulus.
1901368	NAD transmembrane transporter activity	F	Enables the transfer of NAD from one side of the membrane to the other.
1901369	cyclic 2,3-bisphospho-D-glycerate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of cyclic 2,3-bisphospho-D-glyceric acid.
1901370	response to glutathione	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glutathione stimulus.
1901371	regulation of leaf morphogenesis	P	Any process that modulates the frequency, rate or extent of leaf morphogenesis.
1901372	trehalose biosynthetic process involved in ascospore formation	P	Any trehalose biosynthetic process that is involved in ascospore formation.
1901373	lipid hydroperoxide transport	P	The directed movement of a lipid hydroperoxide into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
1901374	acetate ester transport	P	The directed movement of an acetate ester into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
1901375	acetate ester transmembrane transporter activity	F	Enables the transfer of an acetate ester from one side of the membrane to the other.
1901376	organic heteropentacyclic compound metabolic process	P	The chemical reactions and pathways involving organic heteropentacyclic compound.
1901377	organic heteropentacyclic compound catabolic process	P	The chemical reactions and pathways resulting in the breakdown of organic heteropentacyclic compound.
1901378	organic heteropentacyclic compound biosynthetic process	P	The chemical reactions and pathways resulting in the formation of organic heteropentacyclic compound.
1901379	regulation of potassium ion transmembrane transport	P	Any process that modulates the frequency, rate or extent of potassium ion transmembrane transport.
1901380	negative regulation of potassium ion transmembrane transport	P	Any process that stops, prevents or reduces the frequency, rate or extent of potassium ion transmembrane transport.
1901381	positive regulation of potassium ion transmembrane transport	P	Any process that activates or increases the frequency, rate or extent of potassium ion transmembrane transport.
1901382	regulation of chorionic trophoblast cell proliferation	P	Any process that modulates the frequency, rate or extent of chorionic trophoblast cell proliferation.
1901383	negative regulation of chorionic trophoblast cell proliferation	P	Any process that stops, prevents or reduces the frequency, rate or extent of chorionic trophoblast cell proliferation.
1901384	positive regulation of chorionic trophoblast cell proliferation	P	Any process that activates or increases the frequency, rate or extent of chorionic trophoblast cell proliferation.
1901385	regulation of voltage-gated calcium channel activity	P	Any process that modulates the frequency, rate or extent of voltage-gated calcium channel activity.
1901386	negative regulation of voltage-gated calcium channel activity	P	Any process that stops, prevents or reduces the frequency, rate or extent of voltage-gated calcium channel activity.
1901387	positive regulation of voltage-gated calcium channel activity	P	Any process that activates or increases the frequency, rate or extent of voltage-gated calcium channel activity.
1901388	regulation of transforming growth factor beta activation	P	Any process that modulates the frequency, rate or extent of transforming growth factor beta activation.
1901389	negative regulation of transforming growth factor beta activation	P	Any process that stops, prevents or reduces the frequency, rate or extent of transforming growth factor beta activation.
1901390	positive regulation of transforming growth factor beta activation	P	Any process that activates or increases the frequency, rate or extent of transforming growth factor beta activation.
1901392	regulation of transforming growth factor beta1 activation	P	Any process that modulates the frequency, rate or extent of transforming growth factor beta1 activation.
1901393	negative regulation of transforming growth factor beta1 activation	P	Any process that stops, prevents or reduces the frequency, rate or extent of transforming growth factor beta1 activation.
1901394	positive regulation of transforming growth factor beta1 activation	P	Any process that activates or increases the frequency, rate or extent of transforming growth factor beta1 activation.
1901395	regulation of transforming growth factor beta2 activation	P	Any process that modulates the frequency, rate or extent of transforming growth factor beta2 activation.
1901396	negative regulation of transforming growth factor beta2 activation	P	Any process that stops, prevents or reduces the frequency, rate or extent of transforming growth factor beta2 activation.
1901397	positive regulation of transforming growth factor beta2 activation	P	Any process that activates or increases the frequency, rate or extent of transforming growth factor beta2 activation.
1901398	regulation of transforming growth factor beta3 activation	P	Any process that modulates the frequency, rate or extent of transforming growth factor beta3 activation.
1901399	negative regulation of transforming growth factor beta3 activation	P	Any process that stops, prevents or reduces the frequency, rate or extent of transforming growth factor beta3 activation.
1901400	positive regulation of transforming growth factor beta3 activation	P	Any process that activates or increases the frequency, rate or extent of transforming growth factor beta3 activation.
1901401	regulation of tetrapyrrole metabolic process	P	Any process that modulates the frequency, rate or extent of tetrapyrrole metabolic process.
1901402	negative regulation of tetrapyrrole metabolic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of tetrapyrrole metabolic process.
1901403	positive regulation of tetrapyrrole metabolic process	P	Any process that activates or increases the frequency, rate or extent of tetrapyrrole metabolic process.
1901404	regulation of tetrapyrrole catabolic process	P	Any process that modulates the frequency, rate or extent of tetrapyrrole catabolic process.
1901405	negative regulation of tetrapyrrole catabolic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of tetrapyrrole catabolic process.
1901406	positive regulation of tetrapyrrole catabolic process	P	Any process that activates or increases the frequency, rate or extent of tetrapyrrole catabolic process.
1901407	regulation of phosphorylation of RNA polymerase II C-terminal domain	P	Any process that modulates the frequency, rate or extent of phosphorylation of RNA polymerase II C-terminal domain.
1901408	negative regulation of phosphorylation of RNA polymerase II C-terminal domain	P	Any process that stops, prevents or reduces the frequency, rate or extent of phosphorylation of RNA polymerase II C-terminal domain.
1901409	positive regulation of phosphorylation of RNA polymerase II C-terminal domain	P	Any process that activates or increases the frequency, rate or extent of phosphorylation of RNA polymerase II C-terminal domain.
1901410	regulation of tetrapyrrole biosynthetic process from glutamate	P	Any process that modulates the frequency, rate or extent of tetrapyrrole biosynthetic process from glutamate.
1901411	negative regulation of tetrapyrrole biosynthetic process from glutamate	P	Any process that stops, prevents or reduces the frequency, rate or extent of tetrapyrrole biosynthetic process from glutamate.
1901412	positive regulation of tetrapyrrole biosynthetic process from glutamate	P	Any process that activates or increases the frequency, rate or extent of tetrapyrrole biosynthetic process from glutamate.
1901413	regulation of tetrapyrrole biosynthetic process from glycine and succinyl-CoA	P	Any process that modulates the frequency, rate or extent of tetrapyrrole biosynthetic process from glycine and succinyl-CoA.
1901414	negative regulation of tetrapyrrole biosynthetic process from glycine and succinyl-CoA	P	Any process that stops, prevents or reduces the frequency, rate or extent of tetrapyrrole biosynthetic process from glycine and succinyl-CoA.
1901415	positive regulation of tetrapyrrole biosynthetic process from glycine and succinyl-CoA	P	Any process that activates or increases the frequency, rate or extent of tetrapyrrole biosynthetic process from glycine and succinyl-CoA.
1901416	regulation of response to ethanol	P	Any process that modulates the frequency, rate or extent of response to ethanol.
1901417	negative regulation of response to ethanol	P	Any process that stops, prevents or reduces the frequency, rate or extent of response to ethanol.
1901418	positive regulation of response to ethanol	P	Any process that activates or increases the frequency, rate or extent of response to ethanol.
1901419	regulation of response to alcohol	P	Any process that modulates the frequency, rate or extent of response to alcohol.
1901420	negative regulation of response to alcohol	P	Any process that stops, prevents or reduces the frequency, rate or extent of response to alcohol.
1901421	positive regulation of response to alcohol	P	Any process that activates or increases the frequency, rate or extent of response to alcohol.
1901422	response to butan-1-ol	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a butan-1-ol stimulus.
1901423	response to benzene	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a benzene stimulus.
1901424	response to toluene	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a toluene stimulus.
1901425	response to formic acid	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a formic acid stimulus.
1901426	response to furfural	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a furfural stimulus.
1901427	response to propan-1-ol	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a propan-1-ol stimulus.
1901428	regulation of syringal lignin biosynthetic process	P	Any process that modulates the frequency, rate or extent of syringal lignin biosynthetic process.
1901429	negative regulation of syringal lignin biosynthetic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of syringal lignin biosynthetic process.
1901430	positive regulation of syringal lignin biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of syringal lignin biosynthetic process.
1901431	regulation of response to cycloalkane	P	Any process that modulates the frequency, rate or extent of response to cycloalkane.
1901432	negative regulation of response to cycloalkane	P	Any process that stops, prevents or reduces the frequency, rate or extent of response to cycloalkane.
1901433	positive regulation of response to cycloalkane	P	Any process that activates or increases the frequency, rate or extent of response to cycloalkane.
1901434	regulation of toluene catabolic process	P	Any process that modulates the frequency, rate or extent of toluene catabolic process.
1901435	negative regulation of toluene catabolic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of toluene catabolic process.
1901436	positive regulation of toluene catabolic process	P	Any process that activates or increases the frequency, rate or extent of toluene catabolic process.
1901437	regulation of toluene metabolic process	P	Any process that modulates the frequency, rate or extent of toluene metabolic process.
1901438	negative regulation of toluene metabolic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of toluene metabolic process.
1901439	positive regulation of toluene metabolic process	P	Any process that activates or increases the frequency, rate or extent of toluene metabolic process.
1901440	poly(hydroxyalkanoate) metabolic process	P	The chemical reactions and pathways involving poly(hydroxyalkanoate).
1901441	poly(hydroxyalkanoate) biosynthetic process	P	The chemical reactions and pathways resulting in the formation of poly(hydroxyalkanoate).
1901442	regulation of response to furfural	P	Any process that modulates the frequency, rate or extent of response to furfural.
1901443	negative regulation of response to furfural	P	Any process that stops, prevents or reduces the frequency, rate or extent of response to furfural.
1901444	positive regulation of response to furfural	P	Any process that activates or increases the frequency, rate or extent of response to furfural.
1901445	regulation of response to propan-1-ol	P	Any process that modulates the frequency, rate or extent of response to propan-1-ol.
1901446	negative regulation of response to propan-1-ol	P	Any process that stops, prevents or reduces the frequency, rate or extent of response to propan-1-ol.
1901447	positive regulation of response to propan-1-ol	P	Any process that activates or increases the frequency, rate or extent of response to propan-1-ol.
1901448	regulation of response to butan-1-ol	P	Any process that modulates the frequency, rate or extent of response to butan-1-ol.
1901449	negative regulation of response to butan-1-ol	P	Any process that stops, prevents or reduces the frequency, rate or extent of response to butan-1-ol.
1901450	positive regulation of response to butan-1-ol	P	Any process that activates or increases the frequency, rate or extent of response to butan-1-ol.
1901451	regulation of response to benzene	P	Any process that modulates the frequency, rate or extent of response to benzene.
1901452	negative regulation of response to benzene	P	Any process that stops, prevents or reduces the frequency, rate or extent of response to benzene.
1901453	positive regulation of response to benzene	P	Any process that activates or increases the frequency, rate or extent of response to benzene.
1901454	regulation of response to toluene	P	Any process that modulates the frequency, rate or extent of response to toluene.
1901455	negative regulation of response to toluene	P	Any process that stops, prevents or reduces the frequency, rate or extent of response to toluene.
1901456	positive regulation of response to toluene	P	Any process that activates or increases the frequency, rate or extent of response to toluene.
1901457	regulation of response to acetate	P	Any process that modulates the frequency, rate or extent of response to acetate.
1901458	negative regulation of response to acetate	P	Any process that stops, prevents or reduces the frequency, rate or extent of response to acetate.
1901459	positive regulation of response to acetate	P	Any process that activates or increases the frequency, rate or extent of response to acetate.
1901460	regulation of response to formic acid	P	Any process that modulates the frequency, rate or extent of response to formic acid.
1901461	negative regulation of response to formic acid	P	Any process that stops, prevents or reduces the frequency, rate or extent of response to formic acid.
1901462	positive regulation of response to formic acid	P	Any process that activates or increases the frequency, rate or extent of response to formic acid.
1901463	regulation of tetrapyrrole biosynthetic process	P	Any process that modulates the frequency, rate or extent of tetrapyrrole biosynthetic process.
1901464	negative regulation of tetrapyrrole biosynthetic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of tetrapyrrole biosynthetic process.
1901465	positive regulation of tetrapyrrole biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of tetrapyrrole biosynthetic process.
1901466	regulation of ferulate catabolic process	P	Any process that modulates the frequency, rate or extent of ferulate catabolic process.
1901467	negative regulation of ferulate catabolic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of ferulate catabolic process.
1901468	positive regulation of ferulate catabolic process	P	Any process that activates or increases the frequency, rate or extent of ferulate catabolic process.
1901469	regulation of syringal lignin catabolic process	P	Any process that modulates the frequency, rate or extent of syringal lignin catabolic process.
1901470	negative regulation of syringal lignin catabolic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of syringal lignin catabolic process.
1901471	positive regulation of syringal lignin catabolic process	P	Any process that activates or increases the frequency, rate or extent of syringal lignin catabolic process.
1901472	regulation of Golgi calcium ion export	P	Any process that modulates the frequency, rate or extent of Golgi calcium ion export.
1901474	azole transmembrane transporter activity	F	Enables the transfer of azole from one side of the membrane to the other.
1901475	pyruvate transmembrane transport	P	The directed movement of pyruvate across a membrane.
1901476	carbohydrate transporter activity	F	Enables the directed movement of carbohydrate into, out of or within a cell, or between cells.
1901477	benomyl transmembrane transport	P	The directed movement of benomyl across a membrane.
1901478	aminotriazole transmembrane transporter activity	F	Enables the transfer of amitrole from one side of the membrane to the other.
1901479	benomyl transmembrane transporter activity	F	Enables the transfer of benomyl from one side of the membrane to the other.
1901480	oleate transporter activity	F	Enables the directed movement of oleate into, out of or within a cell, or between cells.
1901481	L-glutamate import involved in cellular response to nitrogen starvation	P	Any L-glutamate import that is involved in cellular response to nitrogen starvation.
1901482	L-lysine import involved in cellular response to nitrogen starvation	P	Any L-lysine import that is involved in cellular response to nitrogen starvation.
1901483	regulation of transcription factor catabolic process	P	Any process that modulates the frequency, rate or extent of transcription factor catabolic process.
1901484	negative regulation of transcription factor catabolic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of transcription factor catabolic process.
1901485	positive regulation of transcription factor catabolic process	P	Any process that activates or increases the frequency, rate or extent of transcription factor catabolic process.
1901486	negative regulation of SREBP signaling pathway by positive regulation of transcription factor catabolic process	P	Positive regulation of transcription factor catabolism that results in negative regulation of the SREBP signaling pathway.
1901487	negative regulation of SREBP signaling pathway by positive regulation of transcription factor catabolic process in response to increased oxygen levels	P	Positive regulation of transcription factor catabolism in response to increased oxygen levels, which results in negative regulation of the SREBP signaling pathway.
1901488	positive regulation of SREBP signaling pathway by negative regulation of transcription factor catabolic process	P	Negative regulation of transcription factor catabolism that results in positive regulation of the SREBP signaling pathway.
1901489	positive regulation of SREBP signaling pathway by negative regulation of transcription factor catabolic process in response to decreased oxygen levels	P	Negative regulation of transcription factor catabolism in response to decreased oxygen levels, which results in positive regulation of the SREBP signaling pathway.
1901490	regulation of lymphangiogenesis	P	Any process that modulates the frequency, rate or extent of lymphangiogenesis.
1901491	negative regulation of lymphangiogenesis	P	Any process that stops, prevents or reduces the frequency, rate or extent of lymphangiogenesis.
1901492	positive regulation of lymphangiogenesis	P	Any process that activates or increases the frequency, rate or extent of lymphangiogenesis.
1901493	response to decalin	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a decalin stimulus.
1901494	regulation of cysteine metabolic process	P	Any process that modulates the frequency, rate or extent of cysteine metabolic process.
1901495	negative regulation of cysteine metabolic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of cysteine metabolic process.
1901496	positive regulation of cysteine metabolic process	P	Any process that activates or increases the frequency, rate or extent of cysteine metabolic process.
1901497	response to diphenyl ether	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diphenyl ether stimulus.
1901498	response to tetralin	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tetralin stimulus.
1901499	response to hexane	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hexane stimulus.
1901500	response to p-xylene	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a p-xylene stimulus.
1901501	response to xylene	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a xylene stimulus.
1901502	ether catabolic process	P	The chemical reactions and pathways resulting in the breakdown of ether.
1901503	ether biosynthetic process	P	The chemical reactions and pathways resulting in the formation of ether.
1901504	triazole transport	P	The directed movement of a triazole into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
1901505	carbohydrate derivative transporter activity	F	Enables the directed movement of carbohydrate derivative into, out of or within a cell, or between cells.
1901506	regulation of acylglycerol transport	P	Any process that modulates the frequency, rate or extent of acylglycerol transport.
1901507	negative regulation of acylglycerol transport	P	Any process that stops, prevents or reduces the frequency, rate or extent of acylglycerol transport.
1901508	positive regulation of acylglycerol transport	P	Any process that activates or increases the frequency, rate or extent of acylglycerol transport.
1901509	regulation of endothelial tube morphogenesis	P	Any process that modulates the frequency, rate or extent of endothelial tube morphogenesis.
1901510	(-)-microperfuranone metabolic process	P	The chemical reactions and pathways involving (-)-microperfuranone.
1901511	(-)-microperfuranone catabolic process	P	The chemical reactions and pathways resulting in the breakdown of (-)-microperfuranone.
1901512	(-)-microperfuranone biosynthetic process	P	The chemical reactions and pathways resulting in the formation of (-)-microperfuranone.
1901513	lipo-chitin oligosaccharide transmembrane transporter activity	F	Enables the transfer of lipo-chitin oligosaccharide from one side of the membrane to the other.
1901514	ATPase-coupled lipo-chitin oligosaccharide transmembrane transporter activity	F	Catalysis of the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + lipo-chitin oligosaccharide(in) = ADP + phosphate + lipo-chitin oligosaccharide(out).
1901515	poly-beta-1,6-N-acetyl-D-glucosamine transmembrane transporter activity	F	Enables the transfer of poly-beta-1,6-N-acetyl-D-glucosamine from one side of the membrane to the other.
1901516	aspyridone A metabolic process	P	The chemical reactions and pathways involving aspyridone A.
1901517	aspyridone A catabolic process	P	The chemical reactions and pathways resulting in the breakdown of aspyridone A.
1901518	aspyridone A biosynthetic process	P	The chemical reactions and pathways resulting in the formation of aspyridone A.
1901519	aspyridone B metabolic process	P	The chemical reactions and pathways involving aspyridone B.
1901520	aspyridone B catabolic process	P	The chemical reactions and pathways resulting in the breakdown of aspyridone B.
1901521	aspyridone B biosynthetic process	P	The chemical reactions and pathways resulting in the formation of aspyridone B.
1901522	positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus	P	Any positive regulation of transcription from RNA polymerase II promoter that is involved in cellular response to chemical stimulus.
1901523	icosanoid catabolic process	P	The chemical reactions and pathways resulting in the breakdown of icosanoid.
1901524	regulation of macromitophagy	P	Any process that modulates the frequency, rate or extent of macromitophagy.
1901525	negative regulation of macromitophagy	P	Any process that stops, prevents or reduces the frequency, rate or extent of macromitophagy.
1901526	positive regulation of macromitophagy	P	Any process that activates or increases the frequency, rate or extent of macromitophagy.
1901527	abscisic acid-activated signaling pathway involved in stomatal movement	P	Any abscisic acid mediated signaling pathway that is involved in stomatal movement.
1901528	hydrogen peroxide mediated signaling pathway involved in stomatal movement	P	Any hydrogen peroxide mediated signaling pathway that is involved in stomatal movement.
1901529	positive regulation of anion channel activity	P	Any process that activates or increases the frequency, rate or extent of anion channel activity.
1901530	response to hypochlorite	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hypochlorite stimulus.
1901531	hypochlorite binding	F	Interacting selectively and non-covalently with hypochlorite.
1901532	regulation of hematopoietic progenitor cell differentiation	P	Any process that modulates the frequency, rate or extent of hematopoietic progenitor cell differentiation.
1901533	negative regulation of hematopoietic progenitor cell differentiation	P	Any process that stops, prevents or reduces the frequency, rate or extent of hematopoietic progenitor cell differentiation.
1901534	positive regulation of hematopoietic progenitor cell differentiation	P	Any process that activates or increases the frequency, rate or extent of hematopoietic progenitor cell differentiation.
1901535	regulation of DNA demethylation	P	Any process that modulates the frequency, rate or extent of DNA demethylation.
1901536	negative regulation of DNA demethylation	P	Any process that stops, prevents or reduces the frequency, rate or extent of DNA demethylation.
1901537	positive regulation of DNA demethylation	P	Any process that activates or increases the frequency, rate or extent of DNA demethylation.
1901538	changes to DNA methylation involved in embryo development	P	The addition or removal of methyl groups to DNA that contributes to the epigenetic regulation of embryonic gene expression.
1901539	ent-pimara-8(14),15-diene metabolic process	P	The chemical reactions and pathways involving ent-pimara-8(14),15-diene.
1901540	ent-pimara-8(14),15-diene catabolic process	P	The chemical reactions and pathways resulting in the breakdown of ent-pimara-8(14),15-diene.
1901541	ent-pimara-8(14),15-diene biosynthetic process	P	The chemical reactions and pathways resulting in the formation of ent-pimara-8(14),15-diene.
1901542	regulation of ent-pimara-8(14),15-diene biosynthetic process	P	Any process that modulates the frequency, rate or extent of ent-pimara-8(14),15-diene biosynthetic process.
1901543	negative regulation of ent-pimara-8(14),15-diene biosynthetic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of ent-pimara-8(14),15-diene biosynthetic process.
1901544	positive regulation of ent-pimara-8(14),15-diene biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of ent-pimara-8(14),15-diene biosynthetic process.
1901545	response to raffinose	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a raffinose stimulus.
1901546	regulation of synaptic vesicle lumen acidification	P	Any process that modulates the frequency, rate or extent of synaptic vesicle lumen acidification.
1901547	negative regulation of synaptic vesicle lumen acidification	P	Any process that stops, prevents or reduces the frequency, rate or extent of synaptic vesicle lumen acidification.
1901548	positive regulation of synaptic vesicle lumen acidification	P	Any process that activates or increases the frequency, rate or extent of synaptic vesicle lumen acidification.
1901549	malonic acid uptake transmembrane transporter activity	F	Enables the transfer of malonic acid from the outside of a cell to the inside across a membrane.
1901550	regulation of endothelial cell development	P	Any process that modulates the frequency, rate or extent of endothelial cell development.
1901551	negative regulation of endothelial cell development	P	Any process that stops, prevents or reduces the frequency, rate or extent of endothelial cell development.
1901552	positive regulation of endothelial cell development	P	Any process that activates or increases the frequency, rate or extent of endothelial cell development.
1901553	malonic acid transmembrane transport	P	The directed movement of malonic acid across a membrane.
1901554	response to paracetamol	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a paracetamol stimulus.
1901555	response to paclitaxel	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a paclitaxel stimulus.
1901556	response to candesartan	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a candesartan stimulus.
1901557	response to fenofibrate	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fenofibrate stimulus.
1901558	response to metformin	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a metformin stimulus.
1901559	response to ribavirin	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ribavirin stimulus.
1901560	response to purvalanol A	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a purvalanol A stimulus.
1901561	response to benomyl	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a benomyl stimulus.
1901562	response to paraquat	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a paraquat stimulus.
1901563	response to camptothecin	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a camptothecin stimulus.
1901564	organonitrogen compound metabolic process	P	The chemical reactions and pathways involving organonitrogen compound.
1901565	organonitrogen compound catabolic process	P	The chemical reactions and pathways resulting in the breakdown of organonitrogen compound.
1901566	organonitrogen compound biosynthetic process	P	The chemical reactions and pathways resulting in the formation of organonitrogen compound.
1901567	fatty acid derivative binding	F	Interacting selectively and non-covalently with fatty acid derivative.
1901568	fatty acid derivative metabolic process	P	The chemical reactions and pathways involving fatty acid derivative.
1901569	fatty acid derivative catabolic process	P	The chemical reactions and pathways resulting in the breakdown of fatty acid derivative.
1901570	fatty acid derivative biosynthetic process	P	The chemical reactions and pathways resulting in the formation of fatty acid derivative.
1901571	fatty acid derivative transport	P	The directed movement of a fatty acid derivative into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
1901575	organic substance catabolic process	P	The chemical reactions and pathways resulting in the breakdown of an organic substance, any molecular entity containing carbon.
1901576	organic substance biosynthetic process	P	The chemical reactions and pathways resulting in the formation of an organic substance, any molecular entity containing carbon.
1901577	regulation of alkane biosynthetic process	P	Any process that modulates the frequency, rate or extent of alkane biosynthetic process.
1901578	negative regulation of alkane biosynthetic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of alkane biosynthetic process.
1901579	positive regulation of alkane biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of alkane biosynthetic process.
1901580	regulation of telomeric RNA transcription from RNA pol II promoter	P	Any process that modulates the frequency, rate or extent of telomeric RNA transcription from RNA pol II promoter.
1901581	negative regulation of telomeric RNA transcription from RNA pol II promoter	P	Any process that stops, prevents or reduces the frequency, rate or extent of telomeric RNA transcription from RNA pol II promoter.
1901582	positive regulation of telomeric RNA transcription from RNA pol II promoter	P	Any process that activates or increases the frequency, rate or extent of telomeric RNA transcription from RNA pol II promoter.
1901583	tetrapeptide transmembrane transport	P	The directed movement of tetrapeptide across a membrane.
1901584	tetrapeptide transmembrane transporter activity	F	Enables the transfer of tetrapeptide from one side of the membrane to the other.
1901585	regulation of acid-sensing ion channel activity	P	Any process that modulates the frequency, rate or extent of acid-sensing ion channel activity.
1901586	negative regulation of acid-sensing ion channel activity	P	Any process that stops, prevents or reduces the frequency, rate or extent of acid-sensing ion channel activity.
1901587	positive regulation of acid-sensing ion channel activity	P	Any process that activates or increases the frequency, rate or extent of acid-sensing ion channel activity.
1901588	dendritic microtubule	C	Any microtubule in a dendrite, a neuron projection.
1901589	axon microtubule bundle	C	An arrangement of closely apposed microtubules running parallel to each other in the axon hillock and initial segment.
1901591	regulation of double-strand break repair via break-induced replication	P	Any process that modulates the frequency, rate or extent of double-strand break repair via break-induced replication.
1901592	negative regulation of double-strand break repair via break-induced replication	P	Any process that stops, prevents or reduces the frequency, rate or extent of double-strand break repair via break-induced replication.
1901593	response to GW 7647	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a GW 7647 stimulus.
1901594	response to capsazepine	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a capsazepine stimulus.
1901595	response to hesperadin	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hesperadin stimulus.
1901596	response to reversine	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a reversine stimulus.
1901597	response to carbendazim	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carbendazim stimulus.
1901598	(-)-pinoresinol metabolic process	P	The chemical reactions and pathways involving (-)-pinoresinol.
1901599	(-)-pinoresinol biosynthetic process	P	The chemical reactions and pathways resulting in the formation of (-)-pinoresinol.
1901600	strigolactone metabolic process	P	The chemical reactions and pathways involving strigolactone.
1901601	strigolactone biosynthetic process	P	The chemical reactions and pathways resulting in the formation of strigolactone.
1901602	dethiobiotin binding	F	Interacting selectively and non-covalently with dethiobiotin.
1901603	biotin transmembrane transporter activity	F	Enables the transfer of biotin from one side of the membrane to the other.
1901604	dethiobiotin transmembrane transporter activity	F	Enables the transfer of dethiobiotin from one side of the membrane to the other.
1901605	alpha-amino acid metabolic process	P	The chemical reactions and pathways involving an alpha-amino acid.
1901606	alpha-amino acid catabolic process	P	The chemical reactions and pathways resulting in the breakdown of an alpha-amino acid.
1901607	alpha-amino acid biosynthetic process	P	The chemical reactions and pathways resulting in the formation of an alpha-amino acid.
1901608	regulation of vesicle transport along microtubule	P	Any process that modulates the frequency, rate or extent of vesicle transport along microtubule.
1901609	negative regulation of vesicle transport along microtubule	P	Any process that stops, prevents or reduces the frequency, rate or extent of vesicle transport along microtubule.
1901610	positive regulation of vesicle transport along microtubule	P	Any process that activates or increases the frequency, rate or extent of vesicle transport along microtubule.
1901611	phosphatidylglycerol binding	F	Interacting selectively and non-covalently with phosphatidylglycerol.
1901612	cardiolipin binding	F	Interacting selectively and non-covalently with cardiolipin.
1901613	negative regulation of terminal button organization	P	Any process that stops, prevents or reduces the frequency, rate or extent of terminal button organization.
1901614	positive regulation of terminal button organization	P	Any process that activates or increases the frequency, rate or extent of terminal button organization.
1901615	organic hydroxy compound metabolic process	P	The chemical reactions and pathways involving organic hydroxy compound.
1901616	organic hydroxy compound catabolic process	P	The chemical reactions and pathways resulting in the breakdown of organic hydroxy compound.
1901617	organic hydroxy compound biosynthetic process	P	The chemical reactions and pathways resulting in the formation of organic hydroxy compound.
1901618	organic hydroxy compound transmembrane transporter activity	F	Enables the transfer of organic hydroxy compound from one side of the membrane to the other.
1901619	tRNA methylation in response to nitrogen starvation	P	The posttranscriptional addition of methyl groups to specific residues in a tRNA molecule as a result of deprivation of nitrogen.
1901620	regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning	P	Any process that modulates the frequency, rate or extent of smoothened signaling pathway involved in dorsal/ventral neural tube patterning.
1901621	negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning	P	Any process that stops, prevents or reduces the frequency, rate or extent of smoothened signaling pathway involved in dorsal/ventral neural tube patterning.
1901622	positive regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning	P	Any process that activates or increases the frequency, rate or extent of smoothened signaling pathway involved in dorsal/ventral neural tube patterning.
1901623	regulation of lymphocyte chemotaxis	P	Any process that modulates the frequency, rate or extent of lymphocyte chemotaxis.
1901624	negative regulation of lymphocyte chemotaxis	P	Any process that stops, prevents or reduces the frequency, rate or extent of lymphocyte chemotaxis.
1901625	cellular response to ergosterol	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ergosterol stimulus.
1901626	regulation of postsynaptic membrane organization	P	Any process that modulates the frequency, rate or extent of postsynaptic membrane organization.
1901627	negative regulation of postsynaptic membrane organization	P	Any process that stops, prevents or reduces the frequency, rate or extent of postsynaptic membrane organization.
1901628	positive regulation of postsynaptic membrane organization	P	Any process that activates or increases the frequency, rate or extent of postsynaptic membrane organization.
1901629	regulation of presynaptic membrane organization	P	Any process that modulates the frequency, rate or extent of presynaptic membrane organization.
1901630	negative regulation of presynaptic membrane organization	P	Any process that stops, prevents or reduces the frequency, rate or extent of presynaptic membrane organization.
1901631	positive regulation of presynaptic membrane organization	P	Any process that activates or increases the frequency, rate or extent of presynaptic membrane organization.
1901632	regulation of synaptic vesicle membrane organization	P	Any process that modulates the frequency, rate or extent of synaptic vesicle membrane organization.
1901633	negative regulation of synaptic vesicle membrane organization	P	Any process that stops, prevents or reduces the frequency, rate or extent of synaptic vesicle membrane organization.
1901634	positive regulation of synaptic vesicle membrane organization	P	Any process that activates or increases the frequency, rate or extent of synaptic vesicle membrane organization.
1901639	XDP catabolic process	P	The chemical reactions and pathways resulting in the breakdown of XDP.
1901640	XTP binding	F	Interacting selectively and non-covalently with XTP.
1901641	ITP binding	F	Interacting selectively and non-covalently with ITP.
1901642	nucleoside transmembrane transport	P	The directed movement of nucleoside across a membrane.
1901643	regulation of tRNA methylation in response to nitrogen starvation	P	Any process that modulates the frequency, rate or extent of tRNA methylation in response to nitrogen starvation.
1901644	positive regulation of tRNA methylation in response to nitrogen starvation	P	Any process that activates or increases the frequency, rate or extent of tRNA methylation in response to nitrogen starvation.
1901645	regulation of synoviocyte proliferation	P	Any process that modulates the frequency, rate or extent of synoviocyte proliferation.
1901646	negative regulation of synoviocyte proliferation	P	Any process that stops, prevents or reduces the frequency, rate or extent of synoviocyte proliferation.
1901647	positive regulation of synoviocyte proliferation	P	Any process that activates or increases the frequency, rate or extent of synoviocyte proliferation.
1901648	regulation of actomyosin contractile ring localization	P	Any process that modulates the frequency, rate or extent of actomyosin contractile ring localization.
1901649	negative regulation of actomyosin contractile ring localization	P	Any process that stops, prevents or reduces the frequency, rate or extent of actomyosin contractile ring localization.
1901650	positive regulation of actomyosin contractile ring localization	P	Any process that activates or increases the frequency, rate or extent of actomyosin contractile ring localization.
1901651	regulation of mitotic chromosome decondensation	P	Any process that modulates the frequency, rate or extent of mitotic chromosome decondensation.
1901652	response to peptide	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptide stimulus.
1901653	cellular response to peptide	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptide stimulus.
1901654	response to ketone	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ketone stimulus.
1901655	cellular response to ketone	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ketone stimulus.
1901656	glycoside transport	P	The directed movement of a glycoside into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
1901657	glycosyl compound metabolic process	P	The chemical reactions and pathways involving glycosyl compound.
1901658	glycosyl compound catabolic process	P	The chemical reactions and pathways resulting in the breakdown of glycosyl compound.
1901659	glycosyl compound biosynthetic process	P	The chemical reactions and pathways resulting in the formation of glycosyl compound.
1901660	calcium ion export	P	The directed movement of calcium ion out of a cell or organelle.
1901661	quinone metabolic process	P	The chemical reactions and pathways involving quinone.
1901662	quinone catabolic process	P	The chemical reactions and pathways resulting in the breakdown of quinone.
1901663	quinone biosynthetic process	P	The chemical reactions and pathways resulting in the formation of quinone.
1901664	regulation of NAD+ ADP-ribosyltransferase activity	P	Any process that modulates the frequency, rate or extent of NAD+ ADP-ribosyltransferase activity.
1901665	negative regulation of NAD+ ADP-ribosyltransferase activity	P	Any process that stops, prevents or reduces the frequency, rate or extent of NAD+ ADP-ribosyltransferase activity.
1901666	positive regulation of NAD+ ADP-ribosyltransferase activity	P	Any process that activates or increases the frequency, rate or extent of NAD+ ADP-ribosyltransferase activity.
1901667	negative regulation of skeletal muscle satellite cell activation involved in skeletal muscle regeneration	P	Any process that stops, prevents or reduces the frequency, rate or extent of satellite cell activation involved in skeletal muscle regeneration.
1901668	regulation of superoxide dismutase activity	P	Any process that modulates the frequency, rate or extent of superoxide dismutase activity.
1901670	negative regulation of superoxide dismutase activity	P	Any process that stops, prevents or reduces the frequency, rate or extent of superoxide dismutase activity.
1901671	positive regulation of superoxide dismutase activity	P	Any process that activates or increases the frequency, rate or extent of superoxide dismutase activity.
1901672	positive regulation of systemic acquired resistance	P	Any process that activates or increases the frequency, rate or extent of systemic acquired resistance.
1901673	regulation of mitotic spindle assembly	P	Any process that modulates the frequency, rate or extent of mitotic spindle assembly.
1901674	regulation of histone H3-K27 acetylation	P	Any process that modulates the frequency, rate or extent of histone H3-K27 acetylation.
1901675	negative regulation of histone H3-K27 acetylation	P	Any process that stops, prevents or reduces the frequency, rate or extent of histone H3-K27 acetylation.
1901676	positive regulation of histone H3-K27 acetylation	P	Any process that activates or increases the frequency, rate or extent of histone H3-K27 acetylation.
1901677	phosphate transmembrane transporter activity	F	Enables the transfer of phosphate from one side of the membrane to the other.
1901678	iron coordination entity transport	P	The directed movement of an iron coordination entity into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
1901679	nucleotide transmembrane transport	P	The directed movement of nucleotide across a membrane.
1901680	sulfur-containing amino acid secondary active transmembrane transporter activity	F	Catalysis of the transfer of sulfur-containing amino acid from one side of the membrane to the other, up its concentration gradient. The transporter binds the solute and undergoes a series of conformational changes. Transport works equally well in either direction and is driven by a chemiosmotic source of energy. Chemiosmotic sources of energy include uniport, symport or antiport.
1901681	sulfur compound binding	F	Interacting selectively and non-covalently with a sulfur compound.
1901682	sulfur compound transmembrane transporter activity	F	Enables the transfer of a sulfur compound from one side of the membrane to the other.
1901683	arsenate ion transmembrane transporter activity	F	Enables the transfer of an arsenate ion from one side of the membrane to the other.
1901684	arsenate ion transmembrane transport	P	The directed movement of arsenate ion across a membrane.
1901685	glutathione derivative metabolic process	P	The chemical reactions and pathways involving glutathione derivative.
1901686	glutathione derivative catabolic process	P	The chemical reactions and pathways resulting in the breakdown of glutathione derivative.
1901687	glutathione derivative biosynthetic process	P	The chemical reactions and pathways resulting in the formation of glutathione derivative.
1901688	pantothenate import	P	The directed movement of pantothenate into a cell or organelle.
1901689	biotin import	P	The directed movement of biotin into a cell or organelle.
1901690	dethiobiotin import	P	The directed movement of dethiobiotin into a cell or organelle.
1901691	proton binding	F	Interacting selectively and non-covalently with proton.
1901692	regulation of compound eye retinal cell apoptotic process	P	Any process that modulates the frequency, rate or extent of compound eye retinal cell apoptotic process.
1901693	negative regulation of compound eye retinal cell apoptotic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of compound eye retinal cell apoptotic process.
1901694	positive regulation of compound eye retinal cell apoptotic process	P	Any process that activates or increases the frequency, rate or extent of compound eye retinal cell apoptotic process.
1901695	tyramine biosynthetic process	P	The chemical reactions and pathways resulting in the formation of tyramine.
1901696	cannabinoid biosynthetic process	P	The chemical reactions and pathways resulting in the formation of cannabinoid.
1901697	olivetolic acid biosynthetic process	P	The chemical reactions and pathways resulting in the formation of olivetolic acid.
1901698	response to nitrogen compound	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrogen compound stimulus.
1901699	cellular response to nitrogen compound	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrogen compound stimulus.
1901700	response to oxygen-containing compound	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oxygen-containing compound stimulus.
1901701	cellular response to oxygen-containing compound	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an oxygen-containing compound stimulus.
1901702	salt transmembrane transporter activity	F	Enables the transfer of salt from one side of the membrane to the other.
1901703	protein localization involved in auxin polar transport	P	Any protein localization that is involved in auxin polar transport.
1901704	L-glutamine biosynthetic process	P	The chemical reactions and pathways resulting in the formation of L-glutamine.
1901705	L-isoleucine biosynthetic process	P	The chemical reactions and pathways resulting in the formation of L-isoleucine.
1901706	mesenchymal cell differentiation involved in bone development	P	The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesenchymal cells of bone as it progresses from its formation to the mature state.
1901707	leptomycin B binding	F	Interacting selectively and non-covalently with leptomycin B.
1901708	(+)-3'-hydroxylarreatricin biosynthetic process	P	The chemical reactions and pathways resulting in the formation of (+)-3'-hydroxylarreatricin.
1901709	(+)-larreatricin metabolic process	P	The chemical reactions and pathways involving (+)-larreatricin.
1901710	regulation of homoserine biosynthetic process	P	Any process that modulates the frequency, rate or extent of homoserine biosynthetic process.
1901711	negative regulation of homoserine biosynthetic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of homoserine biosynthetic process.
1901712	positive regulation of homoserine biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of homoserine biosynthetic process.
1901713	negative regulation of urea catabolic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of urea catabolic process.
1901714	positive regulation of urea catabolic process	P	Any process that activates or increases the frequency, rate or extent of urea catabolic process.
1901715	regulation of gamma-aminobutyric acid catabolic process	P	Any process that modulates the frequency, rate or extent of gamma-aminobutyric acid catabolic process.
1901716	negative regulation of gamma-aminobutyric acid catabolic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of gamma-aminobutyric acid catabolic process.
1901717	positive regulation of gamma-aminobutyric acid catabolic process	P	Any process that activates or increases the frequency, rate or extent of gamma-aminobutyric acid catabolic process.
1901718	regulation of dipeptide transmembrane transport by regulation of transcription from RNA polymerase II promoter	P	A regulation of transcription from RNA polymerase II promoter that results in regulation of dipeptide transmembrane transport.
1901719	regulation of NMS complex assembly	P	Any process that modulates the frequency, rate or extent of NMS complex assembly. The NMS complex is involved in chromosome segregation.
1901720	negative regulation of NMS complex assembly	P	Any process that stops, prevents or reduces the frequency, rate or extent of NMS complex assembly. The NMS complex is involved in chromosome segregation.
1901721	positive regulation of NMS complex assembly	P	Any process that activates or increases the frequency, rate or extent of NMS complex assembly. The NMS complex is involved in chromosome segregation.
1901722	regulation of cell proliferation involved in kidney development	P	Any process that modulates the frequency, rate or extent of cell proliferation involved in kidney development.
1901723	negative regulation of cell proliferation involved in kidney development	P	Any process that stops, prevents or reduces the frequency, rate or extent of cell proliferation involved in kidney development.
1901724	positive regulation of cell proliferation involved in kidney development	P	Any process that activates or increases the frequency, rate or extent of cell proliferation involved in kidney development.
1901725	regulation of histone deacetylase activity	P	Any process that modulates the frequency, rate or extent of histone deacetylase activity.
1901726	negative regulation of histone deacetylase activity	P	Any process that stops, prevents or reduces the frequency, rate or extent of histone deacetylase activity.
1901727	positive regulation of histone deacetylase activity	P	Any process that activates or increases the frequency, rate or extent of histone deacetylase activity.
1901728	monensin A metabolic process	P	The chemical reactions and pathways involving monensin A.
1901729	monensin A catabolic process	P	The chemical reactions and pathways resulting in the breakdown of monensin A.
1901730	monensin A biosynthetic process	P	The chemical reactions and pathways resulting in the formation of monensin A.
1901731	positive regulation of platelet aggregation	P	Any process that activates or increases the frequency, rate or extent of platelet aggregation. Platelet aggregation is the adhesion of one platelet to one or more other platelets via adhesion molecules.
1901732	quercetin metabolic process	P	The chemical reactions and pathways involving quercetin.
1901733	quercetin catabolic process	P	The chemical reactions and pathways resulting in the breakdown of quercetin.
1901734	quercetin biosynthetic process	P	The chemical reactions and pathways resulting in the formation of quercetin.
1901735	(R)-mevalonic acid metabolic process	P	The chemical reactions and pathways involving (R)-mevalonic acid.
1901736	(R)-mevalonic acid catabolic process	P	The chemical reactions and pathways resulting in the breakdown of (R)-mevalonic acid.
1901737	(R)-mevalonic acid biosynthetic process	P	The chemical reactions and pathways resulting in the formation of (R)-mevalonic acid.
1901738	regulation of vitamin A metabolic process	P	Any process that modulates the frequency, rate or extent of vitamin A metabolic process.
1901739	regulation of myoblast fusion	P	Any process that modulates the frequency, rate or extent of myoblast fusion.
1901740	negative regulation of myoblast fusion	P	Any process that stops, prevents or reduces the frequency, rate or extent of myoblast fusion.
1901741	positive regulation of myoblast fusion	P	Any process that activates or increases the frequency, rate or extent of myoblast fusion.
1901742	2-deoxystreptamine metabolic process	P	The chemical reactions and pathways involving 2-deoxystreptamine.
1901743	2-deoxystreptamine catabolic process	P	The chemical reactions and pathways resulting in the breakdown of 2-deoxystreptamine.
1901744	2-deoxystreptamine biosynthetic process	P	The chemical reactions and pathways resulting in the formation of 2-deoxystreptamine.
1901745	prephenate(2-) metabolic process	P	The chemical reactions and pathways involving prephenate(2-).
1901746	prephenate(2-) catabolic process	P	The chemical reactions and pathways resulting in the breakdown of prephenate(2-).
1901747	prephenate(2-) biosynthetic process	P	The chemical reactions and pathways resulting in the formation of prephenate(2-).
1901748	leukotriene D4 metabolic process	P	The chemical reactions and pathways involving leukotriene D4.
1901749	leukotriene D4 catabolic process	P	The chemical reactions and pathways resulting in the breakdown of leukotriene D4.
1901750	leukotriene D4 biosynthetic process	P	The chemical reactions and pathways resulting in the formation of leukotriene D4.
1901751	leukotriene A4 metabolic process	P	The chemical reactions and pathways involving leukotriene A4.
1901752	leukotriene A4 catabolic process	P	The chemical reactions and pathways resulting in the breakdown of leukotriene A4.
1901753	leukotriene A4 biosynthetic process	P	The chemical reactions and pathways resulting in the formation of leukotriene A4.
1901754	vitamin D3 catabolic process	P	The chemical reactions and pathways resulting in the breakdown of vitamin D3.
1901755	vitamin D3 biosynthetic process	P	The chemical reactions and pathways resulting in the formation of vitamin D3.
1901756	butirosin metabolic process	P	The chemical reactions and pathways involving butirosin.
1901757	butirosin catabolic process	P	The chemical reactions and pathways resulting in the breakdown of butirosin.
1901758	butirosin biosynthetic process	P	The chemical reactions and pathways resulting in the formation of butirosin.
1901759	beta-L-Ara4N-lipid A metabolic process	P	The chemical reactions and pathways involving beta-L-Ara4N-lipid A.
1901760	beta-L-Ara4N-lipid A biosynthetic process	P	The chemical reactions and pathways resulting in the formation of beta-L-Ara4N-lipid A which occurs as a result of modification of the lipid A moiety of lipopolysaccharide by the addition of the sugar 4-amino-4-deoxy-L-arabinose (L-Ara4N). This strategy is adopted by pathogenic Gram-negative bacteria to evade cationic antimicrobial peptides produced by the innate immune system.
1901761	oxytetracycline metabolic process	P	The chemical reactions and pathways involving oxytetracycline.
1901762	oxytetracycline catabolic process	P	The chemical reactions and pathways resulting in the breakdown of oxytetracycline.
1901763	oxytetracycline biosynthetic process	P	The chemical reactions and pathways resulting in the formation of oxytetracycline.
1901764	phosphinothricin metabolic process	P	The chemical reactions and pathways involving phosphinothricin.
1901765	phosphinothricin catabolic process	P	The chemical reactions and pathways resulting in the breakdown of phosphinothricin.
1901766	phosphinothricin biosynthetic process	P	The chemical reactions and pathways resulting in the formation of phosphinothricin.
1901767	carbapenem metabolic process	P	The chemical reactions and pathways involving carbapenem.
1901768	carbapenem catabolic process	P	The chemical reactions and pathways resulting in the breakdown of carbapenem.
1901769	carbapenem biosynthetic process	P	The chemical reactions and pathways resulting in the formation of carbapenem.
1901770	daunorubicin catabolic process	P	The chemical reactions and pathways resulting in the breakdown of daunorubicin.
1901771	daunorubicin biosynthetic process	P	The chemical reactions and pathways resulting in the formation of daunorubicin.
1901772	lincomycin metabolic process	P	The chemical reactions and pathways involving lincomycin.
1901773	lincomycin catabolic process	P	The chemical reactions and pathways resulting in the breakdown of lincomycin.
1901774	lincomycin biosynthetic process	P	The chemical reactions and pathways resulting in the formation of lincomycin.
1901775	mitomycin C metabolic process	P	The chemical reactions and pathways involving mitomycin C.
1901776	mitomycin C catabolic process	P	The chemical reactions and pathways resulting in the breakdown of mitomycin C.
1901777	mitomycin C biosynthetic process	P	The chemical reactions and pathways resulting in the formation of mitomycin C.
1901778	pentalenolactone metabolic process	P	The chemical reactions and pathways involving pentalenolactone.
1901779	pentalenolactone catabolic process	P	The chemical reactions and pathways resulting in the breakdown of pentalenolactone.
1901780	pentalenolactone biosynthetic process	P	The chemical reactions and pathways resulting in the formation of pentalenolactone.
1901781	p-cumate metabolic process	P	The chemical reactions and pathways involving p-cumate.
1901782	p-cumate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of p-cumate.
1901783	p-cumate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of p-cumate.
1901784	p-cresol metabolic process	P	The chemical reactions and pathways involving p-cresol.
1901785	p-cresol catabolic process	P	The chemical reactions and pathways resulting in the breakdown of p-cresol.
1901786	p-cresol biosynthetic process	P	The chemical reactions and pathways resulting in the formation of p-cresol.
1901787	benzoyl-CoA metabolic process	P	The chemical reactions and pathways involving benzoyl-CoA.
1901788	benzoyl-CoA catabolic process	P	The chemical reactions and pathways resulting in the breakdown of benzoyl-CoA.
1901789	benzoyl-CoA biosynthetic process	P	The chemical reactions and pathways resulting in the formation of benzoyl-CoA.
1901790	3-(2,3-dihydroxyphenyl)propanoate metabolic process	P	The chemical reactions and pathways involving 3-(2,3-dihydroxyphenyl)propanoate.
1901791	3-(2,3-dihydroxyphenyl)propanoate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of 3-(2,3-dihydroxyphenyl)propanoate.
1901792	3-(2,3-dihydroxyphenyl)propanoate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of 3-(2,3-dihydroxyphenyl)propanoate.
1901793	3-(3-hydroxyphenyl)propanoate metabolic process	P	The chemical reactions and pathways involving 3-(3-hydroxyphenyl)propanoate.
1901794	3-(3-hydroxyphenyl)propanoate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of 3-(3-hydroxyphenyl)propanoate.
1901795	3-(3-hydroxyphenyl)propanoate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of 3-(3-hydroxyphenyl)propanoate.
1901796	regulation of signal transduction by p53 class mediator	P	Any process that modulates the frequency, rate or extent of signal transduction by p53 class mediator.
1901797	negative regulation of signal transduction by p53 class mediator	P	Any process that stops, prevents or reduces the frequency, rate or extent of signal transduction by p53 class mediator.
1901798	positive regulation of signal transduction by p53 class mediator	P	Any process that activates or increases the frequency, rate or extent of signal transduction by p53 class mediator.
1901799	negative regulation of proteasomal protein catabolic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of proteasomal protein catabolic process.
1901800	positive regulation of proteasomal protein catabolic process	P	Any process that activates or increases the frequency, rate or extent of proteasomal protein catabolic process.
1901801	1,5-anhydro-D-fructose metabolic process	P	The chemical reactions and pathways involving 1,5-anhydro-D-fructose.
1901802	1,5-anhydro-D-fructose catabolic process	P	The chemical reactions and pathways resulting in the breakdown of 1,5-anhydro-D-fructose.
1901803	1,5-anhydro-D-fructose biosynthetic process	P	The chemical reactions and pathways resulting in the formation of 1,5-anhydro-D-fructose.
1901804	beta-glucoside metabolic process	P	The chemical reactions and pathways involving beta-glucoside.
1901805	beta-glucoside catabolic process	P	The chemical reactions and pathways resulting in the breakdown of beta-glucoside.
1901806	beta-glucoside biosynthetic process	P	The chemical reactions and pathways resulting in the formation of beta-glucoside.
1901807	capsanthin metabolic process	P	The chemical reactions and pathways involving capsanthin.
1901808	capsanthin catabolic process	P	The chemical reactions and pathways resulting in the breakdown of capsanthin.
1901809	capsanthin biosynthetic process	P	The chemical reactions and pathways resulting in the formation of capsanthin.
1901810	beta-carotene metabolic process	P	The chemical reactions and pathways involving beta-carotene.
1901811	beta-carotene catabolic process	P	The chemical reactions and pathways resulting in the breakdown of beta-carotene.
1901812	beta-carotene biosynthetic process	P	The chemical reactions and pathways resulting in the formation of beta-carotene.
1901813	astaxanthin metabolic process	P	The chemical reactions and pathways involving astaxanthin.
1901814	astaxanthin catabolic process	P	The chemical reactions and pathways resulting in the breakdown of astaxanthin.
1901815	astaxanthin biosynthetic process	P	The chemical reactions and pathways resulting in the formation of astaxanthin.
1901816	beta-zeacarotene metabolic process	P	The chemical reactions and pathways involving beta-zeacarotene.
1901817	beta-zeacarotene catabolic process	P	The chemical reactions and pathways resulting in the breakdown of beta-zeacarotene.
1901818	beta-zeacarotene biosynthetic process	P	The chemical reactions and pathways resulting in the formation of beta-zeacarotene.
1901819	alpha-zeacarotene metabolic process	P	The chemical reactions and pathways involving alpha-zeacarotene.
1901820	alpha-zeacarotene catabolic process	P	The chemical reactions and pathways resulting in the breakdown of alpha-zeacarotene.
1901821	alpha-zeacarotene biosynthetic process	P	The chemical reactions and pathways resulting in the formation of alpha-zeacarotene.
1901822	delta-carotene metabolic process	P	The chemical reactions and pathways involving delta-carotene.
1901823	delta-carotene catabolic process	P	The chemical reactions and pathways resulting in the breakdown of delta-carotene.
1901824	delta-carotene biosynthetic process	P	The chemical reactions and pathways resulting in the formation of delta-carotene.
1901825	zeaxanthin metabolic process	P	The chemical reactions and pathways involving zeaxanthin.
1901826	zeaxanthin catabolic process	P	The chemical reactions and pathways resulting in the breakdown of zeaxanthin.
1901827	zeaxanthin biosynthetic process	P	The chemical reactions and pathways resulting in the formation of zeaxanthin.
1901828	zeaxanthin bis(beta-D-glucoside) metabolic process	P	The chemical reactions and pathways involving zeaxanthin bis(beta-D-glucoside).
1901829	zeaxanthin bis(beta-D-glucoside) catabolic process	P	The chemical reactions and pathways resulting in the breakdown of zeaxanthin bis(beta-D-glucoside).
1901830	zeaxanthin bis(beta-D-glucoside) biosynthetic process	P	The chemical reactions and pathways resulting in the formation of zeaxanthin bis(beta-D-glucoside).
1901831	all-trans-neoxanthin metabolic process	P	The chemical reactions and pathways involving all-trans-neoxanthin.
1901832	all-trans-neoxanthin catabolic process	P	The chemical reactions and pathways resulting in the breakdown of all-trans-neoxanthin.
1901833	all-trans-neoxanthin biosynthetic process	P	The chemical reactions and pathways resulting in the formation of all-trans-neoxanthin.
1901834	regulation of deadenylation-independent decapping of nuclear-transcribed mRNA	P	Any process that modulates the frequency, rate or extent of deadenylation-independent decapping of nuclear-transcribed mRNA.
1901835	positive regulation of deadenylation-independent decapping of nuclear-transcribed mRNA	P	Any process that activates or increases the frequency, rate or extent of deadenylation-independent decapping of nuclear-transcribed mRNA.
1901836	regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter	P	Any process that modulates the frequency, rate or extent of transcription of nuclear large rRNA transcript from RNA polymerase I promoter.
1901837	negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter	P	Any process that stops, prevents or reduces the frequency, rate or extent of transcription of nuclear large rRNA transcript from RNA polymerase I promoter.
1901838	positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter	P	Any process that activates or increases the frequency, rate or extent of transcription of nuclear large rRNA transcript from RNA polymerase I promoter.
1901839	regulation of RNA polymerase I regulatory region sequence-specific DNA binding	P	Any process that modulates the frequency, rate or extent of RNA polymerase I regulatory region sequence-specific DNA binding.
1901840	negative regulation of RNA polymerase I regulatory region sequence-specific DNA binding	P	Any process that stops, prevents or reduces the frequency, rate or extent of RNA polymerase I regulatory region sequence-specific DNA binding.
1901841	regulation of high voltage-gated calcium channel activity	P	Any process that modulates the frequency, rate or extent of high voltage-gated calcium channel activity.
1901842	negative regulation of high voltage-gated calcium channel activity	P	Any process that stops, prevents or reduces the frequency, rate or extent of high voltage-gated calcium channel activity.
1901843	positive regulation of high voltage-gated calcium channel activity	P	Any process that activates or increases the frequency, rate or extent of high voltage-gated calcium channel activity.
1901844	regulation of cell communication by electrical coupling involved in cardiac conduction	P	Any process that modulates the frequency, rate or extent of cell communication by electrical coupling involved in cardiac conduction.
1901845	negative regulation of cell communication by electrical coupling involved in cardiac conduction	P	Any process that stops, prevents or reduces the frequency, rate or extent of cell communication by electrical coupling involved in cardiac conduction.
1901846	positive regulation of cell communication by electrical coupling involved in cardiac conduction	P	Any process that activates or increases the frequency, rate or extent of cell communication by electrical coupling involved in cardiac conduction.
1901847	nicotinate metabolic process	P	The chemical reactions and pathways involving nicotinate.
1901848	nicotinate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of nicotinate.
1901849	nicotinate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of nicotinate.
1901850	7,8-didemethyl-8-hydroxy-5-deazariboflavin metabolic process	P	The chemical reactions and pathways involving 7,8-didemethyl-8-hydroxy-5-deazariboflavin.
1901851	7,8-didemethyl-8-hydroxy-5-deazariboflavin catabolic process	P	The chemical reactions and pathways resulting in the breakdown of 7,8-didemethyl-8-hydroxy-5-deazariboflavin.
1901852	7,8-didemethyl-8-hydroxy-5-deazariboflavin biosynthetic process	P	The chemical reactions and pathways resulting in the formation of 7,8-didemethyl-8-hydroxy-5-deazariboflavin.
1901853	5,6,7,8-tetrahydrosarcinapterin metabolic process	P	The chemical reactions and pathways involving 5,6,7,8-tetrahydrosarcinapterin.
1901854	5,6,7,8-tetrahydrosarcinapterin catabolic process	P	The chemical reactions and pathways resulting in the breakdown of 5,6,7,8-tetrahydrosarcinapterin.
1901855	5,6,7,8-tetrahydrosarcinapterin biosynthetic process	P	The chemical reactions and pathways resulting in the formation of 5,6,7,8-tetrahydrosarcinapterin.
1901856	negative regulation of cellular respiration	P	Any process that stops, prevents or reduces the frequency, rate or extent of cellular respiration.
1901857	positive regulation of cellular respiration	P	Any process that activates or increases the frequency, rate or extent of cellular respiration.
1901858	regulation of mitochondrial DNA metabolic process	P	Any process that modulates the frequency, rate or extent of mitochondrial DNA metabolic process.
1901859	negative regulation of mitochondrial DNA metabolic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of mitochondrial DNA metabolic process.
1901860	positive regulation of mitochondrial DNA metabolic process	P	Any process that activates or increases the frequency, rate or extent of mitochondrial DNA metabolic process.
1901861	regulation of muscle tissue development	P	Any process that modulates the frequency, rate or extent of muscle tissue development.
1901862	negative regulation of muscle tissue development	P	Any process that stops, prevents or reduces the frequency, rate or extent of muscle tissue development.
1901863	positive regulation of muscle tissue development	P	Any process that activates or increases the frequency, rate or extent of muscle tissue development.
1901864	capsorubin metabolic process	P	The chemical reactions and pathways involving capsorubin.
1901865	capsorubin catabolic process	P	The chemical reactions and pathways resulting in the breakdown of capsorubin.
1901866	capsorubin biosynthetic process	P	The chemical reactions and pathways resulting in the formation of capsorubin.
1901867	ecgonine methyl ester metabolic process	P	The chemical reactions and pathways involving ecgonine methyl ester.
1901868	ecgonine methyl ester catabolic process	P	The chemical reactions and pathways resulting in the breakdown of ecgonine methyl ester.
1901869	ecgonine methyl ester biosynthetic process	P	The chemical reactions and pathways resulting in the formation of ecgonine methyl ester.
1901870	ecgonone methyl ester metabolic process	P	The chemical reactions and pathways involving ecgonone methyl ester.
1901871	ecgonone methyl ester catabolic process	P	The chemical reactions and pathways resulting in the breakdown of ecgonone methyl ester.
1901872	ecgonone methyl ester biosynthetic process	P	The chemical reactions and pathways resulting in the formation of ecgonone methyl ester.
1901873	regulation of post-translational protein modification	P	Any process that modulates the frequency, rate or extent of post-translational protein modification.
1901874	negative regulation of post-translational protein modification	P	Any process that stops, prevents or reduces the frequency, rate or extent of post-translational protein modification.
1901875	positive regulation of post-translational protein modification	P	Any process that activates or increases the frequency, rate or extent of post-translational protein modification.
1901876	regulation of calcium ion binding	P	Any process that modulates the frequency, rate or extent of calcium ion binding.
1901877	negative regulation of calcium ion binding	P	Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion binding.
1901878	positive regulation of calcium ion binding	P	Any process that activates or increases the frequency, rate or extent of calcium ion binding.
1901879	regulation of protein depolymerization	P	Any process that modulates the frequency, rate or extent of protein depolymerization.
1901880	negative regulation of protein depolymerization	P	Any process that stops, prevents or reduces the frequency, rate or extent of protein depolymerization.
1901881	positive regulation of protein depolymerization	P	Any process that activates or increases the frequency, rate or extent of protein depolymerization.
1901882	4-hydroxycoumarin metabolic process	P	The chemical reactions and pathways involving 4-hydroxycoumarin.
1901883	4-hydroxycoumarin catabolic process	P	The chemical reactions and pathways resulting in the breakdown of 4-hydroxycoumarin.
1901884	4-hydroxycoumarin biosynthetic process	P	The chemical reactions and pathways resulting in the formation of 4-hydroxycoumarin.
1901885	2-hydroxybenzoyl-CoA metabolic process	P	The chemical reactions and pathways involving 2-hydroxybenzoyl-CoA.
1901886	2-hydroxybenzoyl-CoA catabolic process	P	The chemical reactions and pathways resulting in the breakdown of 2-hydroxybenzoyl-CoA.
1901887	2-hydroxybenzoyl-CoA biosynthetic process	P	The chemical reactions and pathways resulting in the formation of 2-hydroxybenzoyl-CoA.
1901888	regulation of cell junction assembly	P	Any process that modulates the frequency, rate or extent of cell junction assembly.
1901889	negative regulation of cell junction assembly	P	Any process that stops, prevents or reduces the frequency, rate or extent of cell junction assembly.
1901890	positive regulation of cell junction assembly	P	Any process that activates or increases the frequency, rate or extent of cell junction assembly.
1901891	regulation of cell septum assembly	P	Any process that modulates the frequency, rate or extent of cell septum assembly.
1901892	negative regulation of cell septum assembly	P	Any process that stops, prevents or reduces the frequency, rate or extent of cell septum assembly.
1901893	positive regulation of cell septum assembly	P	Any process that activates or increases the frequency, rate or extent of cell septum assembly.
1901894	regulation of calcium-transporting ATPase activity	P	Any process that modulates the frequency, rate or extent of calcium-transporting ATPase activity.
1901895	negative regulation of calcium-transporting ATPase activity	P	Any process that stops, prevents or reduces the frequency, rate or extent of calcium-transporting ATPase activity.
1901896	positive regulation of calcium-transporting ATPase activity	P	Any process that activates or increases the frequency, rate or extent of calcium-transporting ATPase activity.
1901897	regulation of relaxation of cardiac muscle	P	Any process that modulates the frequency, rate or extent of relaxation of cardiac muscle.
1901898	negative regulation of relaxation of cardiac muscle	P	Any process that stops, prevents or reduces the frequency, rate or extent of relaxation of cardiac muscle.
1901899	positive regulation of relaxation of cardiac muscle	P	Any process that activates or increases the frequency, rate or extent of relaxation of cardiac muscle.
1901900	regulation of protein localization to cell division site	P	Any process that modulates the frequency, rate or extent of protein localization to cell division site.
1901901	regulation of protein localization to cell division site involved in cytokinesis	P	Any regulation of protein localization to cell division site that is involved in cytokinesis.
1901902	tyrocidine metabolic process	P	The chemical reactions and pathways involving tyrocidine.
1901903	tyrocidine catabolic process	P	The chemical reactions and pathways resulting in the breakdown of tyrocidine.
1901904	tyrocidine biosynthetic process	P	The chemical reactions and pathways resulting in the formation of tyrocidine.
1901905	response to tamsulosin	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tamsulosin stimulus.
1901906	diadenosine pentaphosphate metabolic process	P	The chemical reactions and pathways involving diadenosine pentaphosphate.
1901907	diadenosine pentaphosphate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of diadenosine pentaphosphate.
1901908	diadenosine hexaphosphate metabolic process	P	The chemical reactions and pathways involving diadenosine hexaphosphate.
1901909	diadenosine hexaphosphate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of diadenosine hexaphosphate.
1901910	adenosine 5'-(hexahydrogen pentaphosphate) metabolic process	P	The chemical reactions and pathways involving adenosine 5'-(hexahydrogen pentaphosphate).
1901911	adenosine 5'-(hexahydrogen pentaphosphate) catabolic process	P	The chemical reactions and pathways resulting in the breakdown of adenosine 5'-(hexahydrogen pentaphosphate).
1901913	regulation of capsule organization	P	Any process that modulates the frequency, rate or extent of capsule organization.
1901914	negative regulation of capsule organization	P	Any process that stops, prevents or reduces the frequency, rate or extent of capsule organization.
1901915	positive regulation of capsule organization	P	Any process that activates or increases the frequency, rate or extent of capsule organization.
1901916	protein kinase activity involved in regulation of protein localization to cell division site involved in cytokinesis	F	Any protein kinase activity that is involved in regulation of protein localization to cell division site involved in cytokinesis.
1901917	regulation of exoribonuclease activity	P	Any process that modulates the frequency, rate or extent of exoribonuclease activity.
1901918	negative regulation of exoribonuclease activity	P	Any process that stops, prevents or reduces the frequency, rate or extent of exoribonuclease activity.
1901919	positive regulation of exoribonuclease activity	P	Any process that activates or increases the frequency, rate or extent of exoribonuclease activity.
1901920	peptidyl-tyrosine dephosphorylation involved in activation of protein kinase activity	P	Any peptidyl-tyrosine dephosphorylation that is involved in activation of protein kinase activity.
1901921	phosphorylation of RNA polymerase II C-terminal domain involved in recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex	P	Any phosphorylation of RNA polymerase II C-terminal domain that is involved in recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex.
1901922	regulation of sclerotium development	P	Any process that modulates the frequency, rate or extent of sclerotium development.
1901923	negative regulation of sclerotium development	P	Any process that stops, prevents or reduces the frequency, rate or extent of sclerotium development.
1901924	positive regulation of sclerotium development	P	Any process that activates or increases the frequency, rate or extent of sclerotium development.
1901925	negative regulation of protein import into nucleus during spindle assembly checkpoint	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the movement of proteins from the cytoplasm into the nucleus, and that occurs as a response to the mitotic cell cycle spindle assembly checkpoint. In S. cerevisiae, this process involves inhibition of the karyopherin/importin Kap121p (also known as Pse1p), which acts as the specific nuclear import receptor for several proteins, including Glc7p. Glc7p functions in opposition to key spindle assembly checkpoint protein Aurora kinase (Ipl1p).
1901926	cadinene metabolic process	P	The chemical reactions and pathways involving cadinene.
1901927	cadinene catabolic process	P	The chemical reactions and pathways resulting in the breakdown of cadinene.
1901928	cadinene biosynthetic process	P	The chemical reactions and pathways resulting in the formation of cadinene.
1901929	alpha-copaene metabolic process	P	The chemical reactions and pathways involving alpha-copaene.
1901930	alpha-copaene catabolic process	P	The chemical reactions and pathways resulting in the breakdown of alpha-copaene.
1901931	alpha-copaene biosynthetic process	P	The chemical reactions and pathways resulting in the formation of alpha-copaene.
1901932	bicyclogermacrene metabolic process	P	The chemical reactions and pathways involving bicyclogermacrene.
1901933	bicyclogermacrene catabolic process	P	The chemical reactions and pathways resulting in the breakdown of bicyclogermacrene.
1901934	bicyclogermacrene biosynthetic process	P	The chemical reactions and pathways resulting in the formation of bicyclogermacrene.
1901935	beta-caryophyllene metabolic process	P	The chemical reactions and pathways involving beta-caryophyllene.
1901936	beta-caryophyllene catabolic process	P	The chemical reactions and pathways resulting in the breakdown of beta-caryophyllene.
1901937	beta-caryophyllene biosynthetic process	P	The chemical reactions and pathways resulting in the formation of beta-caryophyllene.
1901938	(-)-exo-alpha-bergamotene metabolic process	P	The chemical reactions and pathways involving (-)-exo-alpha-bergamotene.
1901939	(-)-exo-alpha-bergamotene catabolic process	P	The chemical reactions and pathways resulting in the breakdown of (-)-exo-alpha-bergamotene.
1901940	(-)-exo-alpha-bergamotene biosynthetic process	P	The chemical reactions and pathways resulting in the formation of (-)-exo-alpha-bergamotene.
1901941	(+)-epi-alpha-bisabolol metabolic process	P	The chemical reactions and pathways involving (+)-epi-alpha-bisabolol.
1901942	(+)-epi-alpha-bisabolol catabolic process	P	The chemical reactions and pathways resulting in the breakdown of (+)-epi-alpha-bisabolol.
1901943	(+)-epi-alpha-bisabolol biosynthetic process	P	The chemical reactions and pathways resulting in the formation of (+)-epi-alpha-bisabolol.
1901944	miltiradiene metabolic process	P	The chemical reactions and pathways involving miltiradiene.
1901945	miltiradiene catabolic process	P	The chemical reactions and pathways resulting in the breakdown of miltiradiene.
1901946	miltiradiene biosynthetic process	P	The chemical reactions and pathways resulting in the formation of miltiradiene.
1901947	5alpha,9alpha,10beta-labda-8(20),13-dien-15-yl diphosphate metabolic process	P	The chemical reactions and pathways involving 5alpha,9alpha,10beta-labda-8(20),13-dien-15-yl diphosphate.
1901948	5alpha,9alpha,10beta-labda-8(20),13-dien-15-yl diphosphate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of 5alpha,9alpha,10beta-labda-8(20),13-dien-15-yl diphosphate.
1901949	5alpha,9alpha,10beta-labda-8(20),13-dien-15-yl diphosphate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of 5alpha,9alpha,10beta-labda-8(20),13-dien-15-yl diphosphate.
1901950	dense core granule transport	P	The directed movement a dense core granule within a cell.
1901951	regulation of anterograde dense core granule transport	P	Any process that modulates the frequency, rate or extent of anterograde dense core granule transport.
1901952	negative regulation of anterograde dense core granule transport	P	Any process that stops, prevents or reduces the frequency, rate or extent of anterograde dense core granule transport.
1901953	positive regulation of anterograde dense core granule transport	P	Any process that activates or increases the frequency, rate or extent of anterograde dense core granule transport.
1901954	regulation of retrograde dense core granule transport	P	Any process that modulates the frequency, rate or extent of retrograde dense core granule transport.
1901955	negative regulation of retrograde dense core granule transport	P	Any process that stops, prevents or reduces the frequency, rate or extent of retrograde dense core granule transport.
1901956	positive regulation of retrograde dense core granule transport	P	Any process that activates or increases the frequency, rate or extent of retrograde dense core granule transport.
1901957	regulation of cutin biosynthetic process	P	Any process that modulates the frequency, rate or extent of cutin biosynthetic process.
1901958	negative regulation of cutin biosynthetic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of cutin biosynthetic process.
1901959	positive regulation of cutin biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of cutin biosynthetic process.
1901960	isobutanol metabolic process	P	The chemical reactions and pathways involving isobutanol.
1901961	isobutanol biosynthetic process	P	The chemical reactions and pathways resulting in the formation of isobutanol.
1901962	S-adenosyl-L-methionine transmembrane transport	P	The directed movement of S-adenosyl-L-methionine across a membrane.
1901963	regulation of cell proliferation involved in outflow tract morphogenesis	P	Any process that modulates the frequency, rate or extent of cell proliferation involved in outflow tract morphogenesis.
1901964	positive regulation of cell proliferation involved in outflow tract morphogenesis	P	Any process that activates or increases the frequency, rate or extent of cell proliferation involved in outflow tract morphogenesis.
1901965	endoplasmic reticulum to chloroplast transport	P	The directed movement of substances from endoplasmic reticulum to chloroplast.
1901966	regulation of cellular response to iron ion starvation	P	Any process that modulates the frequency, rate or extent of cellular response to iron ion starvation.
1901967	negative regulation of cellular response to iron ion starvation	P	Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to iron ion starvation.
1901968	regulation of polynucleotide 3'-phosphatase activity	P	Any process that modulates the frequency, rate or extent of polynucleotide 3'-phosphatase activity.
1901969	positive regulation of polynucleotide 3'-phosphatase activity	P	Any process that activates or increases the frequency, rate or extent of polynucleotide 3'-phosphatase activity.
1901970	positive regulation of mitotic sister chromatid separation	P	Any process that activates or increases the frequency, rate or extent of mitotic sister chromatid separation.
1901971	regulation of DNA-5-methylcytosine glycosylase activity	P	Any process that modulates the frequency, rate or extent of DNA-5-methylcytosine glycosylase activity.
1901972	positive regulation of DNA-5-methylcytosine glycosylase activity	P	Any process that activates or increases the frequency, rate or extent of DNA-5-methylcytosine glycosylase activity.
1901973	proline binding	F	Interacting selectively and non-covalently with proline.
1901974	glycerate transmembrane transporter activity	F	Enables the transfer of glycerate from one side of the membrane to the other.
1901975	glycerate transmembrane transport	P	The directed movement of glycerate across a membrane.
1901976	regulation of cell cycle checkpoint	P	Any process that modulates the frequency, rate or extent of cell cycle checkpoint.
1901977	negative regulation of cell cycle checkpoint	P	Any process that stops, prevents or reduces the frequency, rate or extent of cell cycle checkpoint.
1901978	positive regulation of cell cycle checkpoint	P	Any process that activates or increases the frequency, rate or extent of cell cycle checkpoint.
1901979	regulation of inward rectifier potassium channel activity	P	Any process that modulates the frequency, rate or extent of inward rectifier potassium channel activity.
1901980	positive regulation of inward rectifier potassium channel activity	P	Any process that activates or increases the frequency, rate or extent of inward rectifier potassium channel activity.
1901981	phosphatidylinositol phosphate binding	F	Interacting selectively and non-covalently with phosphatidylinositol phosphate.
1901982	maltose binding	F	Interacting selectively and non-covalently with maltose.
1901983	regulation of protein acetylation	P	Any process that modulates the frequency, rate or extent of protein acetylation.
1901984	negative regulation of protein acetylation	P	Any process that stops, prevents or reduces the frequency, rate or extent of protein acetylation.
1901985	positive regulation of protein acetylation	P	Any process that activates or increases the frequency, rate or extent of protein acetylation.
1901986	response to ketamine	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ketamine stimulus.
1901987	regulation of cell cycle phase transition	P	Any process that modulates the frequency, rate or extent of cell cycle phase transition.
1901988	negative regulation of cell cycle phase transition	P	Any process that stops, prevents or reduces the frequency, rate or extent of cell cycle phase transition.
1901989	positive regulation of cell cycle phase transition	P	Any process that activates or increases the frequency, rate or extent of cell cycle phase transition.
1901990	regulation of mitotic cell cycle phase transition	P	Any process that modulates the frequency, rate or extent of mitotic cell cycle phase transition.
1901991	negative regulation of mitotic cell cycle phase transition	P	Any process that stops, prevents or reduces the frequency, rate or extent of mitotic cell cycle phase transition.
1901992	positive regulation of mitotic cell cycle phase transition	P	Any process that activates or increases the frequency, rate or extent of mitotic cell cycle phase transition.
1901993	regulation of meiotic cell cycle phase transition	P	Any process that modulates the frequency, rate or extent of meiotic cell cycle phase transition.
1901994	negative regulation of meiotic cell cycle phase transition	P	Any process that stops, prevents or reduces the frequency, rate or extent of meiotic cell cycle phase transition.
1901995	positive regulation of meiotic cell cycle phase transition	P	Any process that activates or increases the frequency, rate or extent of meiotic cell cycle phase transition.
1901996	regulation of indoleacetic acid biosynthetic process via tryptophan	P	Any process that modulates the frequency, rate or extent of indoleacetic acid biosynthetic process via tryptophan.
1901997	negative regulation of indoleacetic acid biosynthetic process via tryptophan	P	Any process that stops, prevents or reduces the frequency, rate or extent of indoleacetic acid biosynthetic process via tryptophan.
1901998	toxin transport	P	The directed movement of a toxin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
1901999	homogentisate metabolic process	P	The chemical reactions and pathways involving homogentisate.
1902000	homogentisate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of homogentisate.
1902001	fatty acid transmembrane transport	P	The directed movement of fatty acid across a membrane.
1902002	protein phosphorylation involved in cellular protein catabolic process	P	Any protein phosphorylation that is involved in cellular protein catabolic process.
1902003	regulation of beta-amyloid formation	P	Any process that modulates the frequency, rate or extent of beta-amyloid formation.
1902004	positive regulation of beta-amyloid formation	P	Any process that activates or increases the frequency, rate or extent of beta-amyloid formation.
1902005	regulation of proline biosynthetic process	P	Any process that modulates the frequency, rate or extent of proline biosynthetic process.
1902006	negative regulation of proline biosynthetic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of proline biosynthetic process.
1902007	regulation of toxin transport	P	Any process that modulates the frequency, rate or extent of toxin transport.
1902008	negative regulation of toxin transport	P	Any process that stops, prevents or reduces the frequency, rate or extent of toxin transport.
1902009	positive regulation of toxin transport	P	Any process that activates or increases the frequency, rate or extent of toxin transport.
1902010	negative regulation of translation in response to endoplasmic reticulum stress	P	Any process that stops, prevents, or reduces the frequency, rate or extent of translation as a result of endoplasmic reticulum stress.
1902011	poly(ribitol phosphate) teichoic acid metabolic process	P	The chemical reactions and pathways involving poly(ribitol phosphate) teichoic acid.
1902012	poly(ribitol phosphate) teichoic acid biosynthetic process	P	The chemical reactions and pathways resulting in the formation of poly(ribitol phosphate) teichoic acid.
1902013	poly(glycerol phosphate) teichoic acid metabolic process	P	The chemical reactions and pathways involving poly(glycerol phosphate) teichoic acid.
1902014	poly(glycerol phosphate) teichoic acid biosynthetic process	P	The chemical reactions and pathways resulting in the formation of poly(glycerol phosphate) teichoic acid.
1902015	poly(glucopyranosyl N-acetylgalactosamine 1-phosphate) teichoic acid metabolic process	P	The chemical reactions and pathways involving poly(glucopyranosyl N-acetylgalactosamine 1-phosphate) teichoic acid.
1902016	poly(glucopyranosyl N-acetylgalactosamine 1-phosphate) teichoic acid biosynthetic process	P	The chemical reactions and pathways resulting in the formation of poly(glucopyranosyl N-acetylgalactosamine 1-phosphate) teichoic acid.
1902017	regulation of cilium assembly	P	Any process that modulates the frequency, rate or extent of cilium assembly.
1902018	negative regulation of cilium assembly	P	Any process that stops, prevents or reduces the frequency, rate or extent of cilium assembly.
1902019	regulation of cilium-dependent cell motility	P	Any process that modulates the frequency, rate or extent of cilium-dependent cell motility.
1902020	negative regulation of cilium-dependent cell motility	P	Any process that stops, prevents or reduces the frequency, rate or extent of cilium-dependent cell motility.
1902021	regulation of bacterial-type flagellum-dependent cell motility	P	Any process that modulates the frequency, rate or extent of bacterial-type flagellum-dependent cell motility.
1902022	L-lysine transport	P	The directed movement of a L-lysine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
1902023	L-arginine transport	P	The directed movement of a L-arginine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
1902024	L-histidine transport	P	The directed movement of a L-histidine into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
1902025	nitrate import	P	The directed movement of nitrate into a cell or organelle.
1902026	regulation of cartilage condensation	P	Any process that modulates the frequency, rate or extent of cartilage condensation.
1902027	positive regulation of cartilage condensation	P	Any process that activates or increases the frequency, rate or extent of cartilage condensation.
1902028	regulation of histone H3-K18 acetylation	P	Any process that modulates the frequency, rate or extent of histone H3-K18 acetylation.
1902029	positive regulation of histone H3-K18 acetylation	P	Any process that activates or increases the frequency, rate or extent of histone H3-K18 acetylation.
1902030	negative regulation of histone H3-K18 acetylation	P	Any process that stops, prevents or reduces the frequency, rate or extent of histone H3-K18 acetylation.
1902031	regulation of NADP metabolic process	P	Any process that modulates the frequency, rate or extent of NADP metabolic process.
1902033	regulation of hematopoietic stem cell proliferation	P	Any process that modulates the frequency, rate or extent of hematopoietic stem cell proliferation.
1902034	negative regulation of hematopoietic stem cell proliferation	P	Any process that stops, prevents or reduces the frequency, rate or extent of hematopoietic stem cell proliferation.
1902035	positive regulation of hematopoietic stem cell proliferation	P	Any process that activates or increases the frequency, rate or extent of hematopoietic stem cell proliferation.
1902036	regulation of hematopoietic stem cell differentiation	P	Any process that modulates the frequency, rate or extent of hematopoietic stem cell differentiation.
1902037	negative regulation of hematopoietic stem cell differentiation	P	Any process that stops, prevents or reduces the frequency, rate or extent of hematopoietic stem cell differentiation.
1902038	positive regulation of hematopoietic stem cell differentiation	P	Any process that activates or increases the frequency, rate or extent of hematopoietic stem cell differentiation.
1902039	negative regulation of seed dormancy process	P	Any process that stops, prevents or reduces the frequency, rate or extent of seed dormancy process.
1902040	positive regulation of seed dormancy process	P	Any process that activates or increases the frequency, rate or extent of seed dormancy process.
1902041	regulation of extrinsic apoptotic signaling pathway via death domain receptors	P	Any process that modulates the frequency, rate or extent of extrinsic apoptotic signaling pathway via death domain receptors.
1902042	negative regulation of extrinsic apoptotic signaling pathway via death domain receptors	P	Any process that stops, prevents or reduces the frequency, rate or extent of extrinsic apoptotic signaling pathway via death domain receptors.
1902043	positive regulation of extrinsic apoptotic signaling pathway via death domain receptors	P	Any process that activates or increases the frequency, rate or extent of extrinsic apoptotic signaling pathway via death domain receptors.
1902044	regulation of Fas signaling pathway	P	Any process that modulates the frequency, rate or extent of Fas signaling pathway.
1902045	negative regulation of Fas signaling pathway	P	Any process that stops, prevents or reduces the frequency, rate or extent of Fas signaling pathway.
1902046	positive regulation of Fas signaling pathway	P	Any process that activates or increases the frequency, rate or extent of Fas signaling pathway.
1902047	polyamine transmembrane transport	P	The directed movement of a polyamine macromolecule across a membrane.
1902048	neosartoricin metabolic process	P	The chemical reactions and pathways involving neosartoricin.
1902049	neosartoricin catabolic process	P	The chemical reactions and pathways resulting in the breakdown of neosartoricin.
1902050	neosartoricin biosynthetic process	P	The chemical reactions and pathways resulting in the formation of neosartoricin.
1902051	(25S)-Delta(4)-dafachronate binding	F	Interacting selectively and non-covalently with (25S)-Delta(4)-dafachronate.
1902052	(25S)-Delta(7)-dafachronate binding	F	Interacting selectively and non-covalently with (25S)-Delta(7)-dafachronate.
1902053	regulation of neosartoricin biosynthetic process	P	Any process that modulates the frequency, rate or extent of neosartoricin biosynthetic process.
1902054	negative regulation of neosartoricin biosynthetic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of neosartoricin biosynthetic process.
1902055	positive regulation of neosartoricin biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of neosartoricin biosynthetic process.
1902056	(25S)-Delta(7)-dafachronate metabolic process	P	The chemical reactions and pathways involving (25S)-Delta(7)-dafachronate.
1902057	(25S)-Delta(4)-dafachronate metabolic process	P	The chemical reactions and pathways involving (25S)-Delta(4)-dafachronate.
1902058	regulation of sporocarp development involved in sexual reproduction	P	Any process that modulates the frequency, rate or extent of sporocarp development involved in sexual reproduction.
1902059	negative regulation of sporocarp development involved in sexual reproduction	P	Any process that stops, prevents or reduces the frequency, rate or extent of sporocarp development involved in sexual reproduction.
1902060	positive regulation of sporocarp development involved in sexual reproduction	P	Any process that activates or increases the frequency, rate or extent of sporocarp development involved in sexual reproduction.
1902061	betaine aldehyde metabolic process	P	The chemical reactions and pathways involving betaine aldehyde.
1902062	betaine aldehyde catabolic process	P	The chemical reactions and pathways resulting in the breakdown of betaine aldehyde.
1902063	betaine aldehyde biosynthetic process	P	The chemical reactions and pathways resulting in the formation of betaine aldehyde.
1902064	regulation of transcription from RNA polymerase II promoter involved in spermatogenesis	P	Any regulation of transcription from RNA polymerase II promoter that is involved in spermatogenesis.
1902065	response to L-glutamate	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an L-glutamate stimulus.
1902066	regulation of cell wall pectin metabolic process	P	Any process that modulates the frequency, rate or extent of cell wall pectin metabolic process.
1902067	silicic acid import	P	The directed movement of silicic acid into a cell or organelle. Silicic acid is the bioavailable form of silicon.
1902068	regulation of sphingolipid mediated signaling pathway	P	Any process that modulates the frequency, rate or extent of sphingolipid signaling.
1902069	negative regulation of sphingolipid mediated signaling pathway	P	Any process that stops, prevents or reduces the frequency, rate or extent of sphingolipid signaling.
1902070	positive regulation of sphingolipid mediated signaling pathway	P	Any process that activates or increases the frequency, rate or extent of sphingolipid signaling.
1902071	regulation of hypoxia-inducible factor-1alpha signaling pathway	P	Any process that modulates the frequency, rate or extent of hypoxia-inducible factor-1alpha signaling pathway.
1902072	negative regulation of hypoxia-inducible factor-1alpha signaling pathway	P	Any process that stops, prevents or reduces the frequency, rate or extent of hypoxia-inducible factor-1alpha signaling pathway.
1902073	positive regulation of hypoxia-inducible factor-1alpha signaling pathway	P	Any process that activates or increases the frequency, rate or extent of hypoxia-inducible factor-1alpha signaling pathway.
1902074	response to salt	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a salt stimulus.
1902075	cellular response to salt	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a salt stimulus.
1902076	regulation of lateral motor column neuron migration	P	Any process that modulates the frequency, rate or extent of lateral motor column neuron migration.
1902077	negative regulation of lateral motor column neuron migration	P	Any process that stops, prevents or reduces the frequency, rate or extent of lateral motor column neuron migration.
1902078	positive regulation of lateral motor column neuron migration	P	Any process that activates or increases the frequency, rate or extent of lateral motor column neuron migration.
1902079	D-valine catabolic process	P	The chemical reactions and pathways resulting in the breakdown of D-valine.
1902080	regulation of calcium ion import into sarcoplasmic reticulum	P	Any process that modulates the frequency, rate or extent of calcium ion import into sarcoplasmic reticulum.
1902081	negative regulation of calcium ion import into sarcoplasmic reticulum	P	Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion import into sarcoplasmic reticulum.
1902082	positive regulation of calcium ion import into sarcoplasmic reticulum	P	Any process that activates or increases the frequency, rate or extent of calcium ion import into sarcoplasmic reticulum.
1902083	negative regulation of peptidyl-cysteine S-nitrosylation	P	Any process that stops, prevents or reduces the frequency, rate or extent of peptidyl-cysteine S-nitrosylation.
1902084	fumagillin metabolic process	P	The chemical reactions and pathways involving fumagillin.
1902085	fumagillin catabolic process	P	The chemical reactions and pathways resulting in the breakdown of fumagillin.
1902086	fumagillin biosynthetic process	P	The chemical reactions and pathways resulting in the formation of fumagillin.
1902087	dimethylsulfoniopropionate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of S,S-dimethyl-beta-propiothetin.
1902088	plant-type cell wall loosening involved in abscission	P	Any plant-type cell wall loosening that is involved in abscission.
1902089	cell wall polysaccharide catabolic process involved in lateral root development	P	Any cell wall polysaccharide catabolic process that is involved in lateral root development.
1902090	regulation of fumagillin biosynthetic process	P	Any process that modulates the frequency, rate or extent of fumagillin biosynthetic process.
1902091	negative regulation of fumagillin biosynthetic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of fumagillin biosynthetic process.
1902092	positive regulation of fumagillin biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of fumagillin biosynthetic process.
1902093	positive regulation of flagellated sperm motility	P	Any process that activates or increases the frequency, rate or extent of flagellated sperm motility.
1902094	regulation of cartilage homeostasis	P	Any process that modulates the frequency, rate or extent of cartilage homeostasis.
1902095	negative regulation of cartilage homeostasis	P	Any process that stops, prevents or reduces the frequency, rate or extent of cartilage homeostasis.
1902096	positive regulation of cartilage homeostasis	P	Any process that activates or increases the frequency, rate or extent of cartilage homeostasis.
1902097	positive regulation of transcription from RNA polymerase II promoter involved in defense response to Gram-negative bacterium	P	Any positive regulation of transcription from RNA polymerase II promoter that is involved in defense response to Gram-negative bacterium.
1902098	calcitriol binding	F	Interacting selectively and non-covalently with calcitriol. Calcitriol (1,25-dihydroxycholecalciferol) is the hormonally active form of vitamin D3.
1902099	regulation of metaphase/anaphase transition of cell cycle	P	Any process that modulates the frequency, rate or extent of metaphase/anaphase transition of cell cycle.
1902100	negative regulation of metaphase/anaphase transition of cell cycle	P	Any process that stops, prevents or reduces the frequency, rate or extent of metaphase/anaphase transition of cell cycle.
1902101	positive regulation of metaphase/anaphase transition of cell cycle	P	Any process that activates or increases the frequency, rate or extent of metaphase/anaphase transition of cell cycle.
1902102	regulation of metaphase/anaphase transition of meiotic cell cycle	P	Any process that modulates the frequency, rate or extent of metaphase/anaphase transition of meiotic cell cycle.
1902103	negative regulation of metaphase/anaphase transition of meiotic cell cycle	P	Any process that stops, prevents or reduces the frequency, rate or extent of metaphase/anaphase transition of meiotic cell cycle.
1902104	positive regulation of metaphase/anaphase transition of meiotic cell cycle	P	Any process that activates or increases the frequency, rate or extent of metaphase/anaphase transition of meiotic cell cycle.
1902105	regulation of leukocyte differentiation	P	Any process that modulates the frequency, rate or extent of leukocyte differentiation.
1902106	negative regulation of leukocyte differentiation	P	Any process that stops, prevents or reduces the frequency, rate or extent of leukocyte differentiation.
1902107	positive regulation of leukocyte differentiation	P	Any process that activates or increases the frequency, rate or extent of leukocyte differentiation.
1902108	regulation of mitochondrial membrane permeability involved in apoptotic process	P	Any regulation of mitochondrial membrane permeability that is involved in apoptotic process.
1902109	negative regulation of mitochondrial membrane permeability involved in apoptotic process	P	Any negative regulation of mitochondrial membrane permeability that is involved in apoptotic process.
1902110	positive regulation of mitochondrial membrane permeability involved in apoptotic process	P	Any positive regulation of mitochondrial membrane permeability that is involved in apoptotic process.
1902111	response to diethyl maleate	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diethyl maleate stimulus.
1902112	cellular response to diethyl maleate	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diethyl maleate stimulus.
1902113	nucleotide phosphorylation involved in DNA repair	P	Any nucleotide phosphorylation that is involved in DNA repair.
1902114	D-valine metabolic process	P	The chemical reactions and pathways involving D-valine.
1902115	regulation of organelle assembly	P	Any process that modulates the frequency, rate or extent of organelle assembly.
1902116	negative regulation of organelle assembly	P	Any process that stops, prevents or reduces the frequency, rate or extent of organelle assembly.
1902117	positive regulation of organelle assembly	P	Any process that activates or increases the frequency, rate or extent of organelle assembly.
1902118	calcidiol binding	F	Interacting selectively and non-covalently with calcidiol.
1902119	regulation of meiotic spindle elongation	P	Any process that modulates the frequency, rate or extent of meiotic spindle elongation.
1902120	negative regulation of meiotic spindle elongation	P	Any process that stops, prevents or reduces the frequency, rate or extent of meiotic spindle elongation.
1902121	lithocholic acid binding	F	Interacting selectively and non-covalently with lithocholic acid.
1902122	chenodeoxycholic acid binding	F	Interacting selectively and non-covalently with chenodeoxycholic acid.
1902123	(-)-pinoresinol catabolic process	P	The chemical reactions and pathways resulting in the breakdown of (-)-pinoresinol.
1902124	(+)-pinoresinol metabolic process	P	The chemical reactions and pathways involving (+)-pinoresinol.
1902125	(+)-pinoresinol catabolic process	P	The chemical reactions and pathways resulting in the breakdown of (+)-pinoresinol.
1902126	(+)-pinoresinol biosynthetic process	P	The chemical reactions and pathways resulting in the formation of (+)-pinoresinol.
1902127	(-)-lariciresinol metabolic process	P	The chemical reactions and pathways involving (-)-lariciresinol.
1902128	(-)-lariciresinol catabolic process	P	The chemical reactions and pathways resulting in the breakdown of (-)-lariciresinol.
1902129	(-)-lariciresinol biosynthetic process	P	The chemical reactions and pathways resulting in the formation of (-)-lariciresinol.
1902130	(+)-lariciresinol metabolic process	P	The chemical reactions and pathways involving (+)-lariciresinol.
1902131	(+)-lariciresinol catabolic process	P	The chemical reactions and pathways resulting in the breakdown of (+)-lariciresinol.
1902132	(+)-lariciresinol biosynthetic process	P	The chemical reactions and pathways resulting in the formation of (+)-lariciresinol.
1902133	(+)-secoisolariciresinol metabolic process	P	The chemical reactions and pathways involving (+)-secoisolariciresinol.
1902134	(+)-secoisolariciresinol catabolic process	P	The chemical reactions and pathways resulting in the breakdown of (+)-secoisolariciresinol.
1902135	(+)-secoisolariciresinol biosynthetic process	P	The chemical reactions and pathways resulting in the formation of (+)-secoisolariciresinol.
1902136	(-)-secoisolariciresinol metabolic process	P	The chemical reactions and pathways involving (-)-secoisolariciresinol.
1902137	(-)-secoisolariciresinol catabolic process	P	The chemical reactions and pathways resulting in the breakdown of (-)-secoisolariciresinol.
1902138	(-)-secoisolariciresinol biosynthetic process	P	The chemical reactions and pathways resulting in the formation of (-)-secoisolariciresinol.
1902140	response to inositol	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an inositol stimulus.
1902141	cellular response to inositol	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an inositol stimulus.
1902145	regulation of response to cell cycle checkpoint signaling	P	Any process that modulates the frequency, rate or extent of response to cell cycle checkpoint signaling.
1902146	positive regulation of response to cell cycle checkpoint signaling	P	Any process that activates or increases the frequency, rate or extent of response to cell cycle checkpoint signaling.
1902147	regulation of response to cytokinesis checkpoint signaling	P	Any process that modulates the frequency, rate or extent of response to cytokinesis checkpoint signaling.
1902148	positive regulation of response to cytokinesis checkpoint signaling	P	Any process that activates or increases the frequency, rate or extent of response to cytokinesis checkpoint signaling.
1902151	regulation of response to DNA integrity checkpoint signaling	P	Any process that modulates the frequency, rate or extent of response to DNA integrity checkpoint signaling.
1902152	positive regulation of response to DNA integrity checkpoint signaling	P	Any process that activates or increases the frequency, rate or extent of response to DNA integrity checkpoint signaling.
1902153	regulation of response to DNA damage checkpoint signaling	P	Any process that modulates the frequency, rate or extent of response to DNA damage checkpoint signaling.
1902154	positive regulation of response to DNA damage checkpoint signaling	P	Any process that activates or increases the frequency, rate or extent of response to DNA damage checkpoint signaling.
1902155	regulation of response to G1 DNA damage checkpoint signaling	P	Any process that modulates the frequency, rate or extent of response to G1 DNA damage checkpoint signaling.
1902156	positive regulation of response to G1 DNA damage checkpoint signaling	P	Any process that activates or increases the frequency, rate or extent of response to G1 DNA damage checkpoint signaling.
1902157	regulation of response to G2 DNA damage checkpoint signaling	P	Any process that modulates the frequency, rate or extent of response to G2 DNA damage checkpoint signaling.
1902158	positive regulation of response to G2 DNA damage checkpoint signaling	P	Any process that activates or increases the frequency, rate or extent of response to G2 DNA damage checkpoint signaling.
1902159	regulation of cyclic nucleotide-gated ion channel activity	P	Any process that modulates the frequency, rate or extent of cyclic nucleotide-gated ion channel activity.
1902160	negative regulation of cyclic nucleotide-gated ion channel activity	P	Any process that stops, prevents or reduces the frequency, rate or extent of cyclic nucleotide-gated ion channel activity.
1902161	positive regulation of cyclic nucleotide-gated ion channel activity	P	Any process that activates or increases the frequency, rate or extent of cyclic nucleotide-gated ion channel activity.
1902162	regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator	P	Any process that modulates the frequency, rate or extent of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator.
1902163	negative regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator	P	Any process that stops, prevents or reduces the frequency, rate or extent of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator.
1902164	positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator	P	Any process that activates or increases the frequency, rate or extent of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator.
1902165	regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	P	Any process that modulates the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator.
1902166	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	P	Any process that stops, prevents or reduces the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator.
1902167	positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator	P	Any process that activates or increases the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator.
1902168	response to catechin	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a catechin stimulus.
1902169	cellular response to catechin	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a catechin stimulus.
1902170	cellular response to reactive nitrogen species	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a reactive nitrogen species stimulus.
1902171	regulation of tocopherol cyclase activity	P	Any process that modulates the frequency, rate or extent of tocopherol cyclase activity.
1902172	regulation of keratinocyte apoptotic process	P	Any process that modulates the frequency, rate or extent of keratinocyte apoptotic process.
1902173	negative regulation of keratinocyte apoptotic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of keratinocyte apoptotic process.
1902174	positive regulation of keratinocyte apoptotic process	P	Any process that activates or increases the frequency, rate or extent of keratinocyte apoptotic process.
1902175	regulation of oxidative stress-induced intrinsic apoptotic signaling pathway	P	Any process that modulates the frequency, rate or extent of an oxidative stress-induced intrinsic apoptotic signaling pathway.
1902176	negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway	P	Any process that stops, prevents or reduces the frequency, rate or extent of an oxidative stress-induced intrinsic apoptotic signaling pathway.
1902177	positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway	P	Any process that activates or increases the frequency, rate or extent of an oxidative stress-induced intrinsic apoptotic signaling pathway.
1902178	fibroblast growth factor receptor apoptotic signaling pathway	P	An apoptotic signaling pathway that starts with a ligand binding to, or being withdrawn from, a fibroblast growth factor receptor (FGFR).
1902179	verruculogen metabolic process	P	The chemical reactions and pathways involving verruculogen.
1902180	verruculogen catabolic process	P	The chemical reactions and pathways resulting in the breakdown of verruculogen.
1902181	verruculogen biosynthetic process	P	The chemical reactions and pathways resulting in the formation of verruculogen.
1902182	shoot apical meristem development	P	The process whose specific outcome is the progression of a shoot apical meristem over time, from its formation to the mature structure.
1902183	regulation of shoot apical meristem development	P	Any process that modulates the frequency, rate or extent of shoot apical meristem development.
1902184	negative regulation of shoot apical meristem development	P	Any process that stops, prevents or reduces the frequency, rate or extent of shoot apical meristem development.
1902185	positive regulation of shoot apical meristem development	P	Any process that activates or increases the frequency, rate or extent of shoot apical meristem development.
1902186	regulation of viral release from host cell	P	Any process that modulates the frequency, rate or extent of viral release from host cell.
1902187	negative regulation of viral release from host cell	P	Any process that stops, prevents or reduces the frequency, rate or extent of viral release from host cell.
1902188	positive regulation of viral release from host cell	P	Any process that activates or increases the frequency, rate or extent of viral release from host cell.
1902189	2-methylbutanoyl-CoA(4-) metabolic process	P	The chemical reactions and pathways involving 2-methylbutanoyl-CoA(4-).
1902190	2-methylbutanoyl-CoA(4-) catabolic process	P	The chemical reactions and pathways resulting in the breakdown of 2-methylbutanoyl-CoA(4-).
1902191	2-methylbutanoyl-CoA(4-) biosynthetic process	P	The chemical reactions and pathways resulting in the formation of 2-methylbutanoyl-CoA(4-).
1902192	2-methylbut-2-enoyl-CoA(4-) metabolic process	P	The chemical reactions and pathways involving 2-methylbut-2-enoyl-CoA(4-).
1902193	2-methylbut-2-enoyl-CoA(4-) catabolic process	P	The chemical reactions and pathways resulting in the breakdown of 2-methylbut-2-enoyl-CoA(4-).
1902194	2-methylbut-2-enoyl-CoA(4-) biosynthetic process	P	The chemical reactions and pathways resulting in the formation of 2-methylbut-2-enoyl-CoA(4-).
1902195	isovaleryl-CoA(4-) metabolic process	P	The chemical reactions and pathways involving isovaleryl-CoA(4-).
1902196	isovaleryl-CoA(4-) catabolic process	P	The chemical reactions and pathways resulting in the breakdown of isovaleryl-CoA(4-).
1902197	isovaleryl-CoA(4-) biosynthetic process	P	The chemical reactions and pathways resulting in the formation of isovaleryl-CoA(4-).
1902198	3-methylbut-2-enoyl-CoA(4-) metabolic process	P	The chemical reactions and pathways involving 3-methylbut-2-enoyl-CoA(4-).
1902199	3-methylbut-2-enoyl-CoA(4-) catabolic process	P	The chemical reactions and pathways resulting in the breakdown of 3-methylbut-2-enoyl-CoA(4-).
1902200	3-methylbut-2-enoyl-CoA(4-) biosynthetic process	P	The chemical reactions and pathways resulting in the formation of 3-methylbut-2-enoyl-CoA(4-).
1902201	negative regulation of bacterial-type flagellum-dependent cell motility	P	Any process that stops, prevents or reduces the frequency, rate or extent of bacterial-type flagellum-dependent cell motility.
1902202	regulation of hepatocyte growth factor receptor signaling pathway	P	Any process that modulates the frequency, rate or extent of hepatocyte growth factor receptor signaling pathway.
1902203	negative regulation of hepatocyte growth factor receptor signaling pathway	P	Any process that stops, prevents or reduces the frequency, rate or extent of hepatocyte growth factor receptor signaling pathway.
1902204	positive regulation of hepatocyte growth factor receptor signaling pathway	P	Any process that activates or increases the frequency, rate or extent of hepatocyte growth factor receptor signaling pathway.
1902205	regulation of interleukin-2-mediated signaling pathway	P	Any process that modulates the frequency, rate or extent of interleukin-2-mediated signaling pathway.
1902206	negative regulation of interleukin-2-mediated signaling pathway	P	Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-2-mediated signaling pathway.
1902207	positive regulation of interleukin-2-mediated signaling pathway	P	Any process that activates or increases the frequency, rate or extent of interleukin-2-mediated signaling pathway.
1902208	regulation of bacterial-type flagellum assembly	P	Any process that modulates the frequency, rate or extent of bacterial-type flagellum assembly.
1902209	negative regulation of bacterial-type flagellum assembly	P	Any process that stops, prevents or reduces the frequency, rate or extent of bacterial-type flagellum assembly.
1902210	positive regulation of bacterial-type flagellum assembly	P	Any process that activates or increases the frequency, rate or extent of bacterial-type flagellum assembly.
1902211	regulation of prolactin signaling pathway	P	Any process that modulates the frequency, rate or extent of prolactin signaling pathway.
1902212	negative regulation of prolactin signaling pathway	P	Any process that stops, prevents or reduces the frequency, rate or extent of prolactin signaling pathway.
1902213	positive regulation of prolactin signaling pathway	P	Any process that activates or increases the frequency, rate or extent of prolactin signaling pathway.
1902214	regulation of interleukin-4-mediated signaling pathway	P	Any process that modulates the frequency, rate or extent of interleukin-4-mediated signaling pathway.
1902215	negative regulation of interleukin-4-mediated signaling pathway	P	Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-4-mediated signaling pathway.
1902216	positive regulation of interleukin-4-mediated signaling pathway	P	Any process that activates or increases the frequency, rate or extent of interleukin-4-mediated signaling pathway.
1902217	erythrocyte apoptotic process	P	Any apoptotic process in an erythrocyte.
1902218	regulation of intrinsic apoptotic signaling pathway in response to osmotic stress	P	Any process that modulates the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to osmotic stress.
1902219	negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress	P	Any process that stops, prevents or reduces the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to osmotic stress.
1902220	positive regulation of intrinsic apoptotic signaling pathway in response to osmotic stress	P	Any process that activates or increases the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to osmotic stress.
1902221	erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process	P	The chemical reactions and pathways involving erythrose 4-phosphate/phosphoenolpyruvate family amino acid.
1902222	erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process	P	The chemical reactions and pathways resulting in the breakdown of erythrose 4-phosphate/phosphoenolpyruvate family amino acid.
1902223	erythrose 4-phosphate/phosphoenolpyruvate family amino acid biosynthetic process	P	The chemical reactions and pathways resulting in the formation of erythrose 4-phosphate/phosphoenolpyruvate family amino acid.
1902224	ketone body metabolic process	P	The chemical reactions and pathways involving ketone body.
1902225	negative regulation of acrosome reaction	P	Any process that stops, prevents or reduces the frequency, rate or extent of acrosome reaction.
1902226	regulation of macrophage colony-stimulating factor signaling pathway	P	Any process that modulates the frequency, rate or extent of macrophage colony-stimulating factor signaling pathway.
1902227	negative regulation of macrophage colony-stimulating factor signaling pathway	P	Any process that stops, prevents or reduces the frequency, rate or extent of macrophage colony-stimulating factor signaling pathway.
1902228	positive regulation of macrophage colony-stimulating factor signaling pathway	P	Any process that activates or increases the frequency, rate or extent of macrophage colony-stimulating factor signaling pathway.
1902229	regulation of intrinsic apoptotic signaling pathway in response to DNA damage	P	Any process that modulates the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to DNA damage.
1902230	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage	P	Any process that stops, prevents or reduces the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to DNA damage.
1902231	positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage	P	Any process that activates or increases the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to DNA damage.
1902232	regulation of positive thymic T cell selection	P	Any process that modulates the frequency, rate or extent of positive thymic T cell selection.
1902233	negative regulation of positive thymic T cell selection	P	Any process that stops, prevents or reduces the frequency, rate or extent of positive thymic T cell selection.
1902234	positive regulation of positive thymic T cell selection	P	Any process that activates or increases the frequency, rate or extent of positive thymic T cell selection.
1902235	regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway	P	Any process that modulates the frequency, rate or extent of an endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway.
1902236	negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway	P	Any process that stops, prevents or reduces the frequency, rate or extent of an endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway.
1902237	positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway	P	Any process that activates or increases the frequency, rate or extent of an endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway.
1902238	regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator	P	Any process that modulates the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator.
1902239	negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator	P	Any process that stops, prevents or reduces the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator.
1902240	positive regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator	P	Any process that activates or increases the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator.
1902241	copal-8-ol diphosphate(3-) metabolic process	P	The chemical reactions and pathways involving copal-8-ol diphosphate(3-).
1902242	copal-8-ol diphosphate(3-) catabolic process	P	The chemical reactions and pathways resulting in the breakdown of copal-8-ol diphosphate(3-).
1902243	copal-8-ol diphosphate(3-) biosynthetic process	P	The chemical reactions and pathways resulting in the formation of copal-8-ol diphosphate(3-).
1902244	cis-abienol metabolic process	P	The chemical reactions and pathways involving cis-abienol.
1902245	cis-abienol catabolic process	P	The chemical reactions and pathways resulting in the breakdown of cis-abienol.
1902246	cis-abienol biosynthetic process	P	The chemical reactions and pathways resulting in the formation of cis-abienol.
1902247	geranylgeranyl diphosphate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of geranylgeranyl diphosphate.
1902248	5-O-phosphono-alpha-D-ribofuranosyl diphosphate binding	F	Interacting selectively and non-covalently with 5-O-phosphono-alpha-D-ribofuranosyl diphosphate.
1902249	IMP binding	F	Interacting selectively and non-covalently with IMP, inosine monophosphate.
1902250	regulation of erythrocyte apoptotic process	P	Any process that modulates the frequency, rate or extent of erythrocyte apoptotic process.
1902251	negative regulation of erythrocyte apoptotic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of erythrocyte apoptotic process.
1902252	positive regulation of erythrocyte apoptotic process	P	Any process that activates or increases the frequency, rate or extent of erythrocyte apoptotic process.
1902253	regulation of intrinsic apoptotic signaling pathway by p53 class mediator	P	Any process that modulates the frequency, rate or extent of intrinsic apoptotic signaling pathway by p53 class mediator.
1902254	negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator	P	Any process that stops, prevents or reduces the frequency, rate or extent of intrinsic apoptotic signaling pathway by p53 class mediator.
1902255	positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator	P	Any process that activates or increases the frequency, rate or extent of intrinsic apoptotic signaling pathway by p53 class mediator.
1902256	regulation of apoptotic process involved in outflow tract morphogenesis	P	Any process that modulates the frequency, rate or extent of apoptotic process involved in outflow tract morphogenesis.
1902257	negative regulation of apoptotic process involved in outflow tract morphogenesis	P	Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic process involved in outflow tract morphogenesis.
1902258	positive regulation of apoptotic process involved in outflow tract morphogenesis	P	Any process that activates or increases the frequency, rate or extent of apoptotic process involved in outflow tract morphogenesis.
1902259	regulation of delayed rectifier potassium channel activity	P	Any process that modulates the frequency, rate or extent of delayed rectifier potassium channel activity.
1902260	negative regulation of delayed rectifier potassium channel activity	P	Any process that stops, prevents or reduces the frequency, rate or extent of delayed rectifier potassium channel activity.
1902261	positive regulation of delayed rectifier potassium channel activity	P	Any process that activates or increases the frequency, rate or extent of delayed rectifier potassium channel activity.
1902262	apoptotic process involved in blood vessel morphogenesis	P	Any apoptotic process that is involved in blood vessel morphogenesis.
1902263	apoptotic process involved in embryonic digit morphogenesis	P	Any apoptotic process that is involved in embryonic digit morphogenesis.
1902265	abscisic acid homeostasis	P	Any process involved in the maintenance of an internal steady state of abscisic acid within an organism or cell.
1902266	cellular abscisic acid homeostasis	P	Any biological process involved in the maintenance of an internal steady state of abscisic acid at the level of the cell.
1902267	regulation of polyamine transmembrane transport	P	Any process that modulates the frequency, rate or extent of polyamine transmembrane transport.
1902268	negative regulation of polyamine transmembrane transport	P	Any process that stops, prevents or reduces the frequency, rate or extent of polyamine transmembrane transport.
1902269	positive regulation of polyamine transmembrane transport	P	Any process that activates or increases the frequency, rate or extent of polyamine transmembrane transport.
1902270	(R)-carnitine transmembrane transport	P	The directed movement of (R)-carnitine across a membrane.
1902271	D3 vitamins binding	F	Interacting selectively and non-covalently with D3 vitamins.
1902272	regulation of (R)-carnitine transmembrane transport	P	Any process that modulates the frequency, rate or extent of (R)-carnitine transmembrane transport.
1902273	negative regulation of (R)-carnitine transmembrane transport	P	Any process that stops, prevents or reduces the frequency, rate or extent of (R)-carnitine transmembrane transport.
1902274	positive regulation of (R)-carnitine transmembrane transport	P	Any process that activates or increases the frequency, rate or extent of (R)-carnitine transmembrane transport.
1902275	regulation of chromatin organization	P	Any process that modulates the frequency, rate or extent of chromatin organization.
1902276	regulation of pancreatic amylase secretion	P	Any process that modulates the frequency, rate or extent of pancreatic amylase secretion.
1902277	negative regulation of pancreatic amylase secretion	P	Any process that stops, prevents or reduces the frequency, rate or extent of pancreatic amylase secretion.
1902278	positive regulation of pancreatic amylase secretion	P	Any process that activates or increases the frequency, rate or extent of pancreatic amylase secretion.
1902279	positive regulation of pancreatic amylase secretion by cholecystokinin signaling pathway	P	A cholecystokinin signaling pathway that results in positive regulation of pancreatic amylase secretion.
1902280	regulation of ATP-dependent RNA helicase activity	P	Any process that modulates the frequency, rate or extent of ATP-dependent RNA helicase activity.
1902281	negative regulation of ATP-dependent RNA helicase activity	P	Any process that stops, prevents or reduces the frequency, rate or extent of ATP-dependent RNA helicase activity.
1902282	voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization	F	Enables the transmembrane transfer of a potassium ion by a voltage-gated channel through the plasma membrane of a ventricular cardiomyocyte contributing to the repolarization phase of an action potential. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.
1902283	negative regulation of primary amine oxidase activity	P	Any process that stops, prevents or reduces the frequency, rate or extent of primary amine oxidase activity.
1902284	neuron projection extension involved in neuron projection guidance	P	Any neuron projection extension that is involved in neuron projection guidance.
1902285	semaphorin-plexin signaling pathway involved in neuron projection guidance	P	Any semaphorin-plexin signaling pathway that is involved in neuron projection guidance.
1902286	semaphorin-plexin signaling pathway involved in dendrite guidance	P	Any semaphorin-plexin signaling pathway that is involved in dendrite guidance.
1902287	semaphorin-plexin signaling pathway involved in axon guidance	P	Any semaphorin-plexin signaling pathway that is involved in axon guidance.
1902288	regulation of defense response to oomycetes	P	Any process that modulates the frequency, rate or extent of defense response to oomycetes.
1902289	negative regulation of defense response to oomycetes	P	Any process that stops, prevents or reduces the frequency, rate or extent of defense response to oomycetes.
1902290	positive regulation of defense response to oomycetes	P	Any process that activates or increases the frequency, rate or extent of defense response to oomycetes.
1902291	cell cycle DNA replication DNA ligation	P	Any DNA ligation that is involved in cell cycle DNA replication.
1902292	cell cycle DNA replication initiation	P	Any DNA replication initiation that is involved in cell cycle DNA replication.
1902294	cell cycle DNA replication termination	P	Any DNA replication termination that is involved in cell cycle DNA replication.
1902295	synthesis of RNA primer involved in cell cycle DNA replication	P	Any DNA replication, synthesis of RNA primer that is involved in cell cycle DNA replication.
1902296	DNA strand elongation involved in cell cycle DNA replication	P	Any DNA strand elongation that is involved in cell cycle DNA replication.
1902297	cell cycle DNA replication DNA unwinding	P	Any DNA unwinding that is involved in cell cycle DNA replication.
1902298	cell cycle DNA replication maintenance of fidelity	P	Any maintenance of fidelity that is involved in cell cycle DNA replication.
1902299	pre-replicative complex assembly involved in cell cycle DNA replication	P	Any pre-replicative complex assembly that is involved in cell cycle DNA replication.
1902300	galactarate transport	P	The directed movement of a galactaric acid anion (galactarate) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
1902301	galactarate transmembrane transporter activity	F	Enables the transfer of galactaric acid anion (galactarate) from one side of the membrane to the other.
1902302	regulation of potassium ion export	P	Any process that modulates the frequency, rate or extent of potassium ion export.
1902303	negative regulation of potassium ion export	P	Any process that stops, prevents or reduces the frequency, rate or extent of potassium ion export.
1902304	positive regulation of potassium ion export	P	Any process that activates or increases the frequency, rate or extent of potassium ion export.
1902305	regulation of sodium ion transmembrane transport	P	Any process that modulates the frequency, rate or extent of sodium ion transmembrane transport.
1902306	negative regulation of sodium ion transmembrane transport	P	Any process that stops, prevents or reduces the frequency, rate or extent of sodium ion transmembrane transport.
1902307	positive regulation of sodium ion transmembrane transport	P	Any process that activates or increases the frequency, rate or extent of sodium ion transmembrane transport.
1902308	regulation of peptidyl-serine dephosphorylation	P	Any process that modulates the frequency, rate or extent of peptidyl-serine dephosphorylation.
1902309	negative regulation of peptidyl-serine dephosphorylation	P	Any process that stops, prevents or reduces the frequency, rate or extent of peptidyl-serine dephosphorylation.
1902310	positive regulation of peptidyl-serine dephosphorylation	P	Any process that activates or increases the frequency, rate or extent of peptidyl-serine dephosphorylation.
1902311	regulation of copper ion transmembrane transport	P	Any process that modulates the frequency, rate or extent of copper ion transmembrane transport.
1902312	negative regulation of copper ion transmembrane transport	P	Any process that stops, prevents or reduces the frequency, rate or extent of copper ion transmembrane transport.
1902313	positive regulation of copper ion transmembrane transport	P	Any process that activates or increases the frequency, rate or extent of copper ion transmembrane transport.
1902314	hydroquinone binding	F	Interacting selectively and non-covalently with hydroquinone.
1902315	nuclear cell cycle DNA replication initiation	P	Any DNA replication initiation that is involved in nuclear cell cycle DNA replication.
1902317	nuclear DNA replication termination	P	Any DNA replication termination that is involved in nuclear cell cycle DNA replication.
1902318	synthesis of RNA primer involved in nuclear cell cycle DNA replication	P	Any synthesis of RNA primer that is involved in nuclear cell cycle DNA replication.
1902319	DNA strand elongation involved in nuclear cell cycle DNA replication	P	Any DNA strand elongation that is involved in nuclear cell cycle DNA replication.
1902320	nuclear DNA replication DNA duplex unwinding	P	Any DNA duplex unwinding that is involved in nuclear cell cycle DNA replication.
1902321	methyl-branched fatty acid biosynthetic process	P	The chemical reactions and pathways resulting in the formation of methyl-branched fatty acid.
1902322	regulation of methyl-branched fatty acid biosynthetic process	P	Any process that modulates the frequency, rate or extent of methyl-branched fatty acid biosynthetic process.
1902323	negative regulation of methyl-branched fatty acid biosynthetic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of methyl-branched fatty acid biosynthetic process.
1902324	positive regulation of methyl-branched fatty acid biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of methyl-branched fatty acid biosynthetic process.
1902325	negative regulation of chlorophyll biosynthetic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of chlorophyll biosynthetic process.
1902326	positive regulation of chlorophyll biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of chlorophyll biosynthetic process.
1902327	bacterial-type DNA replication DNA ligation	P	Any DNA ligation that is involved in bacterial-type DNA replication.
1902328	bacterial-type DNA replication initiation	P	Any DNA replication initiation that is involved in bacterial-type DNA replication.
1902329	bacterial-type DNA replication termination	P	Any DNA replication termination that is involved in bacterial-type DNA replication.
1902330	synthesis of RNA primer involved in bacterial-type DNA replication	P	Any synthesis of RNA primer that is involved in bacterial-type DNA replication.
1902331	DNA strand elongation involved in bacterial-type DNA replication	P	Any DNA strand elongation that is involved in bacterial-type DNA replication.
1902332	bacterial-type DNA replication DNA duplex unwinding	P	Any DNA duplex unwinding that is involved in bacterial-type DNA replication.
1902333	nuclear DNA replication DNA ligation	P	Any DNA ligation that is involved in nuclear cell cycle DNA replication.
1902334	fructose export from vacuole to cytoplasm	P	The directed movement of fructose from vacuole to cytoplasm.
1902336	positive regulation of retinal ganglion cell axon guidance	P	Any process that activates or increases the frequency, rate or extent of retinal ganglion cell axon guidance.
1902337	regulation of apoptotic process involved in morphogenesis	P	Any process that modulates the frequency, rate or extent of apoptotic process involved in morphogenesis.
1902338	negative regulation of apoptotic process involved in morphogenesis	P	Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic process involved in morphogenesis.
1902339	positive regulation of apoptotic process involved in morphogenesis	P	Any process that activates or increases the frequency, rate or extent of apoptotic process involved in morphogenesis.
1902340	negative regulation of chromosome condensation	P	Any process that stops, prevents or reduces the frequency, rate or extent of chromosome condensation.
1902341	xylitol transport	P	The directed movement of a xylitol into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Xylitol is a polyalcohol (pentane-1,2,3,4,5-pentol), produced by hydrogenation of xylose.
1902342	xylitol export	P	The directed movement of xylitol out of a cell or organelle.
1902343	regulation of maltose transport	P	Any process that modulates the frequency, rate or extent of maltose transport.
1902344	negative regulation of maltose transport	P	Any process that stops, prevents or reduces the frequency, rate or extent of maltose transport.
1902345	positive regulation of maltose transport	P	Any process that activates or increases the frequency, rate or extent of maltose transport.
1902346	meiotic strand displacement involved in double-strand break repair via SDSA	P	Any meiotic strand displacement that is involved in double-strand break repair via synthesis-dependent strand annealing (SDSA).
1902347	response to strigolactone	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a strigolactone stimulus.
1902348	cellular response to strigolactone	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a strigolactone stimulus.
1902349	response to chloroquine	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chloroquine stimulus.
1902350	cellular response to chloroquine	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chloroquine stimulus.
1902351	response to imidacloprid	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an imidacloprid stimulus.
1902352	negative regulation of filamentous growth of a population of unicellular organisms in response to starvation by negative regulation of transcription from RNA polymerase II promoter	P	A negative regulation of transcription from RNA polymerase II promoter that results in negative regulation of filamentous growth of a population of unicellular organisms in response to starvation.
1902353	positive regulation of induction of conjugation with cellular fusion by negative regulation of transcription from RNA polymerase II promoter by pheromones	P	A negative regulation of transcription from RNA polymerase II promoter by pheromones that results in positive regulation of induction of conjugation with cellular fusion.
1902354	blood vessel endothelial cell delamination involved in blood vessel lumen ensheathment	P	Any blood vessel endothelial cell delamination that is involved in blood vessel lumen ensheathment.
1902355	endothelial tube lumen extension involved in blood vessel lumen ensheathment	P	Any endothelial tube lumen extension that is involved in blood vessel lumen ensheathment.
1902356	oxaloacetate(2-) transmembrane transport	P	The directed movement of oxaloacetate(2-) across a membrane.
1902357	2-isopropylmalate(2-) transmembrane transport	P	The directed movement of 2-isopropylmalate(2-) across a membrane.
1902358	sulfate transmembrane transport	P	The directed movement of sulfate across a membrane.
1902359	Notch signaling pathway involved in somitogenesis	P	Any Notch signaling pathway that is involved in somitogenesis.
1902360	conversion of ds siRNA to ss siRNA involved in chromatin silencing by small RNA	P	Any conversion of ds siRNA to ss siRNA that is involved in chromatin silencing by small RNA.
1902361	mitochondrial pyruvate transmembrane transport	P	The directed movement of pyruvate across a mitochondrial membrane.
1902362	melanocyte apoptotic process	P	Any apoptotic process in a melanocyte, the main structural component of the epidermis.
1902363	regulation of protein localization to spindle pole body	P	Any process that modulates the frequency, rate or extent of protein localization to spindle pole body.
1902364	negative regulation of protein localization to spindle pole body	P	Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to spindle pole body.
1902365	positive regulation of protein localization to spindle pole body	P	Any process that activates or increases the frequency, rate or extent of protein localization to spindle pole body.
1902366	regulation of Notch signaling pathway involved in somitogenesis	P	Any process that modulates the frequency, rate or extent of Notch signaling pathway involved in somitogenesis.
1902367	negative regulation of Notch signaling pathway involved in somitogenesis	P	Any process that stops, prevents or reduces the frequency, rate or extent of Notch signaling pathway involved in somitogenesis.
1902368	heterochromatin maintenance involved in chromatin silencing at centromere outer repeat region	P	Any heterochromatin maintenance that is involved in chromatin silencing at centromere outer repeat region.
1902369	negative regulation of RNA catabolic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of RNA catabolic process.
1902370	regulation of tRNA catabolic process	P	Any process that modulates the frequency, rate or extent of tRNA catabolic process.
1902371	negative regulation of tRNA catabolic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of tRNA catabolic process.
1902372	positive regulation of tRNA catabolic process	P	Any process that activates or increases the frequency, rate or extent of tRNA catabolic process.
1902373	negative regulation of mRNA catabolic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of mRNA catabolic process.
1902374	regulation of rRNA catabolic process	P	Any process that modulates the frequency, rate or extent of rRNA catabolic process.
1902375	nuclear tRNA 3'-trailer cleavage, endonucleolytic	P	Any tRNA 3'-trailer cleavage, endonucleolytic that takes place in nucleus.
1902376	protein denaturation involved in proteasomal ubiquitin-dependent protein catabolic process	P	Any protein denaturation that is involved in proteasomal ubiquitin-dependent protein catabolic process.
1902377	nuclear rDNA heterochromatin	C	Any rDNA heterochromatin that is part of a nucleus.
1902378	VEGF-activated neuropilin signaling pathway involved in axon guidance	P	Any VEGF-activated neuropilin signaling pathway that is involved in axon guidance.
1902379	chemoattractant activity involved in axon guidance	F	Any chemoattractant activity that is involved in axon guidance.
1902380	positive regulation of endoribonuclease activity	P	Any process that activates or increases the frequency, rate or extent of endoribonuclease activity.
1902381	11-oxo-beta-amyrin metabolic process	P	The chemical reactions and pathways involving 11-oxo-beta-amyrin.
1902382	11-oxo-beta-amyrin catabolic process	P	The chemical reactions and pathways resulting in the breakdown of 11-oxo-beta-amyrin.
1902383	11-oxo-beta-amyrin biosynthetic process	P	The chemical reactions and pathways resulting in the formation of 11-oxo-beta-amyrin.
1902384	glycyrrhetinate metabolic process	P	The chemical reactions and pathways involving glycyrrhetinate.
1902385	glycyrrhetinate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of glycyrrhetinate.
1902386	glycyrrhetinate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of glycyrrhetinate.
1902387	ceramide 1-phosphate binding	F	Interacting selectively and non-covalently with ceramide 1-phosphate.
1902388	ceramide 1-phosphate transporter activity	F	Enables the directed movement of ceramide 1-phosphate into, out of or within a cell, or between cells.
1902389	ceramide 1-phosphate transport	P	The directed movement of a ceramide 1-phosphate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
1902390	regulation of N-terminal peptidyl-serine acetylation	P	Any process that modulates the frequency, rate or extent of N-terminal peptidyl-serine acetylation.
1902391	positive regulation of N-terminal peptidyl-serine acetylation	P	Any process that activates or increases the frequency, rate or extent of N-terminal peptidyl-serine acetylation.
1902392	regulation of exodeoxyribonuclease activity	P	Any process that modulates the frequency, rate or extent of exodeoxyribonuclease activity.
1902393	negative regulation of exodeoxyribonuclease activity	P	Any process that stops, prevents or reduces the frequency, rate or extent of exodeoxyribonuclease activity.
1902394	positive regulation of exodeoxyribonuclease activity	P	Any process that activates or increases the frequency, rate or extent of exodeoxyribonuclease activity.
1902395	regulation of 1-deoxy-D-xylulose-5-phosphate synthase activity	P	Any process that modulates the frequency, rate or extent of 1-deoxy-D-xylulose-5-phosphate synthase activity.
1902396	protein localization to bicellular tight junction	P	A process in which a protein is transported to, or maintained in, a location within a tight junction.
1902397	detection of stimulus involved in meiotic spindle checkpoint	P	Any detection of stimulus that is involved in meiotic spindle checkpoint.
1902398	intracellular signal transduction involved in meiotic spindle checkpoint	P	Any intracellular signal transduction that is involved in meiotic spindle checkpoint.
1902399	detection of stimulus involved in G1 DNA damage checkpoint	P	Any detection of stimulus that is involved in G1 DNA damage checkpoint.
1902400	intracellular signal transduction involved in G1 DNA damage checkpoint	P	Any intracellular signal transduction that is involved in G1 DNA damage checkpoint.
1902401	detection of stimulus involved in mitotic DNA damage checkpoint	P	Any detection of stimulus that is involved in mitotic DNA damage checkpoint.
1902402	signal transduction involved in mitotic DNA damage checkpoint	P	Any intracellular signal transduction that is involved in mitotic DNA damage checkpoint.
1902403	signal transduction involved in mitotic DNA integrity checkpoint	P	Any intracellular signal transduction that is involved in mitotic DNA integrity checkpoint.
1902404	mitotic actomyosin contractile ring contraction	P	Any actomyosin contractile ring contraction that is involved in mitotic cell cycle.
1902405	mitotic actomyosin contractile ring localization	P	Any actomyosin contractile ring localization that is involved in mitotic cell cycle.
1902406	mitotic actomyosin contractile ring maintenance	P	Any actomyosin contractile ring maintenance that is involved in mitotic cell cycle.
1902407	assembly of actomyosin apparatus involved in mitotic cytokinesis	P	Any assembly of mitotic cytokinetic actomyosin apparatus.
1902408	mitotic cytokinesis, site selection	P	Any cytokinesis, site selection that is involved in mitotic cell cycle.
1902410	mitotic cytokinetic process	P	Any cytokinetic process that is involved in mitotic cell cycle.
1902412	regulation of mitotic cytokinesis	P	Any process that modulates the frequency, rate or extent of mitotic cytokinesis.
1902413	negative regulation of mitotic cytokinesis	P	Any process that stops, prevents or reduces the frequency, rate or extent of mitotic cytokinesis.
1902414	protein localization to cell junction	P	A process in which a protein is transported to, or maintained in, a location within a cell junction.
1902415	regulation of mRNA binding	P	Any process that modulates the frequency, rate or extent of mRNA binding.
1902416	positive regulation of mRNA binding	P	Any process that activates or increases the frequency, rate or extent of mRNA binding.
1902417	(+)-abscisic acid D-glucopyranosyl ester transmembrane transporter activity	F	Enables the transfer of (+)-abscisic acid D-glucopyranosyl ester from one side of the membrane to the other.
1902418	(+)-abscisic acid D-glucopyranosyl ester transmembrane transport	P	The directed movement of (+)-abscisic acid D-glucopyranosyl ester across a membrane.
1902419	detection of stimulus involved in Dma1-dependent checkpoint	P	Any detection of stimulus that is involved in Dma1-dependent checkpoint.
1902420	signal transduction involved in Dma1-dependent checkpoint	P	Any signal transduction that is involved in Dma1-dependent checkpoint.
1902421	hydrogen metabolic process	P	The chemical reactions and pathways involving H2 (dihydrogen).
1902422	hydrogen biosynthetic process	P	The chemical reactions and pathways resulting in the formation of H2 (dihydrogen).
1902423	regulation of attachment of mitotic spindle microtubules to kinetochore	P	Any process that modulates the frequency, rate or extent of attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation.
1902424	negative regulation of attachment of mitotic spindle microtubules to kinetochore	P	Any process that stops, prevents or reduces the frequency, rate or extent of attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation.
1902425	positive regulation of attachment of mitotic spindle microtubules to kinetochore	P	Any process that activates or increases the frequency, rate or extent of attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation.
1902426	deactivation of mitotic spindle assembly checkpoint	P	A positive regulation of the mitotic metaphase/anaphase transition that results from deactivation of the mitotic spindle assembly checkpoint.
1902427	regulation of water channel activity	P	Any process that modulates the frequency, rate or extent of water channel activity.
1902428	negative regulation of water channel activity	P	Any process that stops, prevents or reduces the frequency, rate or extent of water channel activity.
1902429	positive regulation of water channel activity	P	Any process that activates or increases the frequency, rate or extent of water channel activity.
1902430	negative regulation of beta-amyloid formation	P	Any process that stops, prevents or reduces the frequency, rate or extent of beta-amyloid formation.
1902431	uracil import into cell	P	The directed movement of uracil from outside of a cell into the cytoplasmic compartment. This may occur via transport across the plasma membrane or via endocytosis.
1902432	protein localization to barrier septum	P	A process in which a protein is transported to, or maintained in, a location within a barrier septum.
1902433	positive regulation of water channel activity involved in maintenance of lens transparency	P	Any positive regulation of water channel activity that is involved in maintenance of lens transparency.
1902434	sulfate import into cell	P	The directed movement of sulfate from outside of a cell into the intracellular region of a cell.
1902435	regulation of male mating behavior	P	Any process that modulates the frequency, rate or extent of male mating behavior.
1902436	negative regulation of male mating behavior	P	Any process that stops, prevents or reduces the frequency, rate or extent of male mating behavior.
1902437	positive regulation of male mating behavior	P	Any process that activates or increases the frequency, rate or extent of male mating behavior.
1902438	response to vanadate(3-)	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vanadate(3-) stimulus.
1902439	cellular response to vanadate(3-)	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vanadate(3-) stimulus.
1902440	protein localization to mitotic spindle pole body	P	A process in which a protein is transported to, or maintained in, a location within a mitotic spindle pole body.
1902441	protein localization to meiotic spindle pole body	P	A process in which a protein is transported to, or maintained in, a location within a meiotic spindle pole body.
1902442	regulation of ripoptosome assembly involved in necroptotic process	P	Any process that modulates the frequency, rate or extent of ripoptosome assembly involved in a necroptotic process.
1902443	negative regulation of ripoptosome assembly involved in necroptotic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of ripoptosome assembly involved in a necroptotic process.
1902444	riboflavin binding	F	Interacting selectively and non-covalently with riboflavin.
1902445	regulation of mitochondrial membrane permeability involved in programmed necrotic cell death	P	Any regulation of mitochondrial membrane permeability that is involved in programmed necrotic cell death.
1902446	regulation of shade avoidance	P	Any process that modulates the frequency, rate or extent of shade avoidance.
1902447	negative regulation of shade avoidance	P	Any process that stops, prevents or reduces the frequency, rate or extent of shade avoidance.
1902448	positive regulation of shade avoidance	P	Any process that activates or increases the frequency, rate or extent of shade avoidance.
1902449	regulation of ATP-dependent DNA helicase activity	P	Any process that modulates the frequency, rate or extent of ATP-dependent DNA helicase activity.
1902450	negative regulation of ATP-dependent DNA helicase activity	P	Any process that stops, prevents or reduces the frequency, rate or extent of ATP-dependent DNA helicase activity.
1902451	positive regulation of ATP-dependent DNA helicase activity	P	Any process that activates or increases the frequency, rate or extent of ATP-dependent DNA helicase activity.
1902455	negative regulation of stem cell population maintenance	P	Any process that stops, prevents or reduces the frequency, rate or extent of stem cell population maintenance.
1902456	regulation of stomatal opening	P	Any process that modulates the frequency, rate or extent of stomatal opening.
1902457	negative regulation of stomatal opening	P	Any process that stops, prevents or reduces the frequency, rate or extent of stomatal opening.
1902458	positive regulation of stomatal opening	P	Any process that activates or increases the frequency, rate or extent of stomatal opening.
1902459	positive regulation of stem cell population maintenance	P	Any process that activates or increases the frequency, rate or extent of stem cell population maintenance.
1902460	regulation of mesenchymal stem cell proliferation	P	Any process that modulates the frequency, rate or extent of mesenchymal stem cell proliferation.
1902461	negative regulation of mesenchymal stem cell proliferation	P	Any process that stops, prevents or reduces the frequency, rate or extent of mesenchymal stem cell proliferation.
1902462	positive regulation of mesenchymal stem cell proliferation	P	Any process that activates or increases the frequency, rate or extent of mesenchymal stem cell proliferation.
1902463	protein localization to cell leading edge	P	A process in which a protein is transported to, or maintained in, a location within a cell leading edge.
1902464	regulation of histone H3-K27 trimethylation	P	Any process that modulates the frequency, rate or extent of histone H3-K27 trimethylation.
1902465	negative regulation of histone H3-K27 trimethylation	P	Any process that stops, prevents or reduces the frequency, rate or extent of histone H3-K27 trimethylation.
1902466	positive regulation of histone H3-K27 trimethylation	P	Any process that activates or increases the frequency, rate or extent of histone H3-K27 trimethylation.
1902471	regulation of mitotic actomyosin contractile ring localization	P	Any process that modulates the frequency, rate or extent of mitotic actomyosin contractile ring localization.
1902472	regulation of mitotic cytokinesis, site selection	P	Any process that modulates the frequency, rate or extent of mitotic cytokinesis, site selection.
1902473	regulation of protein localization to synapse	P	Any process that modulates the frequency, rate or extent of protein localization to synapse.
1902474	positive regulation of protein localization to synapse	P	Any process that activates or increases the frequency, rate or extent of protein localization to synapse.
1902475	L-alpha-amino acid transmembrane transport	P	The directed movement of L-alpha-amino acid across a membrane.
1902476	chloride transmembrane transport	P	The directed movement of chloride across a membrane.
1902477	regulation of defense response to bacterium, incompatible interaction	P	Any process that modulates the frequency, rate or extent of defense response to bacterium, incompatible interaction.
1902478	negative regulation of defense response to bacterium, incompatible interaction	P	Any process that stops, prevents or reduces the frequency, rate or extent of defense response to bacterium, incompatible interaction.
1902479	positive regulation of defense response to bacterium, incompatible interaction	P	Any process that activates or increases the frequency, rate or extent of defense response to bacterium, incompatible interaction.
1902480	protein localization to mitotic spindle	P	A process in which a protein is transported to, or maintained in, a location within a mitotic spindle.
1902481	gamma-tubulin complex assembly	P	The aggregation, arrangement and bonding together of a set of components to form a gamma-tubulin complex.
1902482	regulatory T cell apoptotic process	P	Any apoptotic process in a regulatory T cell.
1902483	cytotoxic T cell apoptotic process	P	Any apoptotic process in a cytotoxic T cell.
1902484	Sertoli cell apoptotic process	P	Any apoptotic process in a Sertoli cell.
1902485	L-cysteine binding	F	Interacting selectively and non-covalently with L-cysteine.
1902486	protein localization to growing cell tip	P	A process in which a protein is transported to, or maintained in, a location within a growing cell tip.
1902487	protein localization to non-growing cell tip	P	A process in which a protein is transported to, or maintained in, a location within a non-growing cell tip.
1902488	cholangiocyte apoptotic process	P	Any apoptotic process in a cholangiocyte.
1902489	hepatoblast apoptotic process	P	Any apoptotic process in a hepatoblast.
1902490	regulation of sperm capacitation	P	Any process that modulates the frequency, rate or extent of sperm capacitation.
1902491	negative regulation of sperm capacitation	P	Any process that stops, prevents or reduces the frequency, rate or extent of sperm capacitation.
1902492	positive regulation of sperm capacitation	P	Any process that activates or increases the frequency, rate or extent of sperm capacitation.
1902493	acetyltransferase complex	C	A protein complex which is capable of acetyltransferase activity.
1902494	catalytic complex	C	A protein complex which is capable of catalytic activity.
1902495	transmembrane transporter complex	C	A transmembrane protein complex which enables the transfer of a substance from one side of a membrane to the other.
1902496	protein binding involved in negative regulation of telomere maintenance via telomerase	F	Any protein binding that is involved in negative regulation of telomere maintenance via telomerase.
1902497	iron-sulfur cluster transport	P	The directed movement of an iron-sulfur cluster into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
1902498	regulation of protein autoubiquitination	P	Any process that modulates the frequency, rate or extent of protein autoubiquitination.
1902499	positive regulation of protein autoubiquitination	P	Any process that activates or increases the frequency, rate or extent of protein autoubiquitination.
1902500	vacuolar HOPS complex	C	Any HOPS complex that is part of a vacuolar membrane.
1902501	lysosomal HOPS complex	C	Any HOPS complex that is part of a lysosomal membrane.
1902502	multivesicular body HOPS complex	C	Any HOPS complex that is part of a multivesicular body membrane.
1902503	adenylyltransferase complex	C	A protein complex which is capable of adenylyltransferase activity.
1902504	regulation of signal transduction involved in mitotic G2 DNA damage checkpoint	P	Any process that modulates the frequency, rate or extent of signal transduction involved in mitotic G2 DNA damage checkpoint.
1902505	negative regulation of signal transduction involved in mitotic G2 DNA damage checkpoint	P	Any process that stops, prevents or reduces the frequency, rate or extent of signal transduction involved in mitotic G2 DNA damage checkpoint.
1902506	positive regulation of signal transduction involved in mitotic G2 DNA damage checkpoint	P	Any process that activates or increases the frequency, rate or extent of signal transduction involved in mitotic G2 DNA damage checkpoint.
1902507	thiazole synthase complex	C	A protein complex which is capable of thiazole synthase activity.
1902508	2-iminoacetate synthase complex	C	A protein complex which is capable of 2-iminoacetate synthase activity.
1902509	methionine-importing complex	C	A protein complex which is capable of methionine-importing activity.
1902510	regulation of apoptotic DNA fragmentation	P	Any process that modulates the frequency, rate or extent of apoptotic DNA fragmentation.
1902511	negative regulation of apoptotic DNA fragmentation	P	Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic DNA fragmentation.
1902512	positive regulation of apoptotic DNA fragmentation	P	Any process that activates or increases the frequency, rate or extent of apoptotic DNA fragmentation.
1902513	regulation of organelle transport along microtubule	P	Any process that modulates the frequency, rate or extent of organelle transport along microtubule.
1902514	regulation of calcium ion transmembrane transport via high voltage-gated calcium channel	P	Any process that modulates the frequency, rate or extent of generation of calcium ion transmembrane transport via high voltage-gated calcium channel.
1902515	thioredoxin-disulfide reductase complex	C	A protein complex which is capable of thioredoxin-disulfide reductase activity.
1902516	sn-glycerol 3-phosphate binding	F	Interacting selectively and non-covalently with sn-glycerol 3-phosphate.
1902517	glycerol-3-phosphate-transporting ATPase complex	C	A protein complex which is capable of glycerol-3-phosphate-transporting ATPase activity.
1902518	response to cyclophosphamide	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cyclophosphamide stimulus.
1902519	response to docetaxel trihydrate	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a docetaxel trihydrate stimulus.
1902520	response to doxorubicin	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a doxorubicin stimulus.
1902521	response to etoposide	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an etoposide stimulus.
1902522	response to 4'-epidoxorubicin	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 4'-epidoxorubicin stimulus.
1902523	positive regulation of protein K63-linked ubiquitination	P	Any process that activates or increases the frequency, rate or extent of protein K63-linked ubiquitination.
1902524	positive regulation of protein K48-linked ubiquitination	P	Any process that activates or increases the frequency, rate or extent of protein K48-linked ubiquitination.
1902525	regulation of protein monoubiquitination	P	Any process that modulates the frequency, rate or extent of protein monoubiquitination.
1902526	negative regulation of protein monoubiquitination	P	Any process that stops, prevents or reduces the frequency, rate or extent of protein monoubiquitination.
1902527	positive regulation of protein monoubiquitination	P	Any process that activates or increases the frequency, rate or extent of protein monoubiquitination.
1902528	regulation of protein linear polyubiquitination	P	Any process that modulates the frequency, rate or extent of protein linear polyubiquitination.
1902529	negative regulation of protein linear polyubiquitination	P	Any process that stops, prevents or reduces the frequency, rate or extent of protein linear polyubiquitination.
1902530	positive regulation of protein linear polyubiquitination	P	Any process that activates or increases the frequency, rate or extent of protein linear polyubiquitination.
1902531	regulation of intracellular signal transduction	P	Any process that modulates the frequency, rate or extent of intracellular signal transduction.
1902532	negative regulation of intracellular signal transduction	P	Any process that stops, prevents or reduces the frequency, rate or extent of intracellular signal transduction.
1902533	positive regulation of intracellular signal transduction	P	Any process that activates or increases the frequency, rate or extent of intracellular signal transduction.
1902534	single-organism membrane invagination	P	A membrane invagination which involves only one organism.
1902535	multi-organism membrane invagination	P	A membrane invagination which involves another organism.
1902536	single-organism pinocytosis	P	A pinocytosis which involves only one organism.
1902537	multi-organism pinocytosis	P	A pinocytosis which involves another organism.
1902538	single-organism macropinocytosis	P	A macropinocytosis which involves only one organism.
1902539	multi-organism macropinocytosis	P	A macropinocytosis which involves another organism.
1902540	single-organism micropinocytosis	P	A micropinocytosis which involves only one organism.
1902541	multi-organism micropinocytosis	P	A micropinocytosis which involves another organism.
1902542	regulation of protein localization to mitotic spindle pole body	P	Any process that modulates the frequency, rate or extent of protein localization to mitotic spindle pole body.
1902543	negative regulation of protein localization to mitotic spindle pole body	P	Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to mitotic spindle pole body.
1902544	regulation of DNA N-glycosylase activity	P	Any process that modulates the frequency, rate or extent of DNA N-glycosylase activity.
1902545	negative regulation of DNA N-glycosylase activity	P	Any process that stops, prevents or reduces the frequency, rate or extent of DNA N-glycosylase activity.
1902546	positive regulation of DNA N-glycosylase activity	P	Any process that activates or increases the frequency, rate or extent of DNA N-glycosylase activity.
1902547	regulation of cellular response to vascular endothelial growth factor stimulus	P	Any process that modulates the frequency, rate or extent of cellular response to vascular endothelial growth factor stimulus.
1902548	negative regulation of cellular response to vascular endothelial growth factor stimulus	P	Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to vascular endothelial growth factor stimulus.
1902549	protein localization to Mei2 nuclear dot	P	A process in which a protein is transported to, or maintained in, a location within a Mei2 nuclear dot.
1902550	lymphoid lineage cell migration into thymus involved in thymus epithelium morphogenesis	P	Any lymphoid lineage cell migration into thymus that is involved in thymus epithelium morphogenesis.
1902551	regulation of catalase activity	P	Any process that modulates the frequency, rate or extent of catalase activity.
1902552	negative regulation of catalase activity	P	Any process that stops, prevents or reduces the frequency, rate or extent of catalase activity.
1902553	positive regulation of catalase activity	P	Any process that activates or increases the frequency, rate or extent of catalase activity.
1902554	serine/threonine protein kinase complex	C	A protein complex which is capable of protein serine/threonine kinase activity.
1902555	endoribonuclease complex	C	A protein complex which is capable of endoribonuclease activity.
1902556	phosphatidylinositol transporter complex	C	A protein complex which is capable of phosphatidylinositol transporter activity.
1902557	5'-adenylyl sulfate transmembrane transporter activity	F	Enables the transfer of 5'-adenylyl sulfate from one side of the membrane to the other.
1902558	5'-adenylyl sulfate transmembrane transport	P	The directed movement of 5'-adenylyl sulfate across a membrane.
1902559	3'-phospho-5'-adenylyl sulfate transmembrane transport	P	The directed movement of 3'-phospho-5'-adenylyl sulfate across a membrane.
1902560	GMP reductase complex	C	An oxidoreductase complex which is capable of GMP reductase activity. It catalyses the irreversible reaction: GMP + 2 H(+) + NADPH => IMP + NADP(+) + NH(4)(+).
1902561	origin recognition complex assembly	P	The aggregation, arrangement and bonding together of a set of components to form an origin recognition complex.
1902562	H4 histone acetyltransferase complex	C	A protein complex which is capable of H4 histone acetyltransferase activity.
1902563	regulation of neutrophil activation	P	Any process that modulates the frequency, rate or extent of neutrophil activation.
1902564	negative regulation of neutrophil activation	P	Any process that stops, prevents or reduces the frequency, rate or extent of neutrophil activation.
1902565	positive regulation of neutrophil activation	P	Any process that activates or increases the frequency, rate or extent of neutrophil activation.
1902566	regulation of eosinophil activation	P	Any process that modulates the frequency, rate or extent of eosinophil activation.
1902567	negative regulation of eosinophil activation	P	Any process that stops, prevents or reduces the frequency, rate or extent of eosinophil activation.
1902568	positive regulation of eosinophil activation	P	Any process that activates or increases the frequency, rate or extent of eosinophil activation.
1902569	negative regulation of activation of JAK2 kinase activity	P	Any process that stops, prevents or reduces the frequency, rate or extent of activation of JAK2 kinase activity.
1902570	protein localization to nucleolus	P	A process in which a protein is transported to, or maintained in, a location within a nucleolus.
1902571	regulation of serine-type peptidase activity	P	Any process that modulates the frequency, rate or extent of serine-type peptidase activity.
1902572	negative regulation of serine-type peptidase activity	P	Any process that stops, prevents or reduces the frequency, rate or extent of serine-type peptidase activity.
1902573	positive regulation of serine-type peptidase activity	P	Any process that activates or increases the frequency, rate or extent of serine-type peptidase activity.
1902574	negative regulation of leucine import by regulation of transcription from RNA polymerase II promoter	P	A regulation of transcription from RNA polymerase II promoter that results in negative regulation of leucine import.
1902575	protein localization to cell division site involved in cytokinesis, actomyosin contractile ring assembly	P	Any protein localization to cell division site that is involved in cytokinesis, actomyosin contractile ring assembly.
1902576	negative regulation of nuclear cell cycle DNA replication	P	Any process that stops, prevents or reduces the frequency, rate or extent of nuclear cell cycle DNA replication.
1902577	protein localization to medial cortical node	P	A process in which a protein is transported to, or maintained in, a location within a medial cortical node.
1902578	single-organism localization	P	A localization which involves only one organism.
1902579	multi-organism localization	P	A localization which involves another organism.
1902580	single-organism cellular localization	P	A cellular localization which involves only one organism.
1902581	multi-organism cellular localization	P	A cellular localization which involves another organism.
1902582	single-organism intracellular transport	P	An intracellular transport which involves only one organism.
1902583	multi-organism intracellular transport	P	An intracellular transport which involves another organism.
1902584	positive regulation of response to water deprivation	P	Any process that activates or increases the frequency, rate or extent of response to water deprivation.
1902585	single-organism intercellular transport	P	An intercellular transport which involves only one organism.
1902586	multi-organism intercellular transport	P	An intercellular transport which involves another organism.
1902587	single-organism plasmodesmata-mediated intercellular transport	P	A plasmodesmata-mediated intercellular transport which involves only one organism.
1902588	multi-organism plasmodesmata-mediated intercellular transport	P	A plasmodesmata-mediated intercellular transport which involves another organism.
1902589	single-organism organelle organization	P	An organelle organization which involves only one organism.
1902590	multi-organism organelle organization	P	An organelle organization which involves another organism.
1902591	single-organism membrane budding	P	A membrane budding which involves only one organism.
1902592	multi-organism membrane budding	P	A membrane budding which involves another organism.
1902593	single-organism nuclear import	P	A nuclear import which involves only one organism.
1902594	multi-organism nuclear import	P	A nuclear import which involves another organism.
1902595	regulation of DNA replication origin binding	P	Any process that modulates the frequency, rate or extent of DNA replication origin binding.
1902596	negative regulation of DNA replication origin binding	P	Any process that stops, prevents or reduces the frequency, rate or extent of DNA replication origin binding.
1902597	positive regulation of DNA replication origin binding	P	Any process that activates or increases the frequency, rate or extent of DNA replication origin binding.
1902598	creatine transmembrane transport	P	The directed movement of creatine across a membrane.
1902599	sulfathiazole transmembrane transport	P	The directed movement of sulfathiazole across a membrane.
1902600	hydrogen ion transmembrane transport	P	The directed movement of hydrogen ion (proton) across a membrane.
1902601	silver ion transmembrane transport	P	The directed movement of silver ion across a membrane.
1902602	aluminum ion transmembrane transport	P	The directed movement of aluminium ion across a membrane.
1902603	carnitine transmembrane transport	P	The directed movement of carnitine across a membrane.
1902604	p-aminobenzoyl-glutamate transmembrane transport	P	The directed movement of N-(4-aminobenzoyl)-L-glutamate across a membrane.
1902605	heterotrimeric G-protein complex assembly	P	The aggregation, arrangement and bonding together of a set of components to form a heterotrimeric G-protein complex.
1902606	regulation of large conductance calcium-activated potassium channel activity	P	Any process that modulates the frequency, rate or extent of large conductance calcium-activated potassium channel activity.
1902607	negative regulation of large conductance calcium-activated potassium channel activity	P	Any process that stops, prevents or reduces the frequency, rate or extent of large conductance calcium-activated potassium channel activity.
1902608	positive regulation of large conductance calcium-activated potassium channel activity	P	Any process that activates or increases the frequency, rate or extent of large conductance calcium-activated potassium channel activity.
1902609	(R)-2-hydroxy-alpha-linolenic acid biosynthetic process	P	The chemical reactions and pathways resulting in the formation of (R)-2-hydroxy-alpha-linolenic acid.
1902610	response to N-phenylthiourea	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a N-phenylthiourea stimulus.
1902611	cellular response to N-phenylthiourea	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a N-phenylthiourea stimulus.
1902612	regulation of anti-Mullerian hormone signaling pathway	P	Any process that modulates the frequency, rate or extent of anti-Mullerian hormone signaling pathway.
1902613	negative regulation of anti-Mullerian hormone signaling pathway	P	Any process that stops, prevents or reduces the frequency, rate or extent of anti-Mullerian hormone signaling pathway.
1902614	positive regulation of anti-Mullerian hormone signaling pathway	P	Any process that activates or increases the frequency, rate or extent of anti-Mullerian hormone signaling pathway.
1902615	immune response involved in response to exogenous dsRNA	P	Any immune response that is involved in response to exogenous dsRNA.
1902616	acyl carnitine transmembrane transport	P	The directed movement of acyl carnitine across a membrane.
1902617	response to fluoride	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fluoride stimulus.
1902618	cellular response to fluoride	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a fluoride stimulus.
1902619	regulation of microtubule minus-end binding	P	Any process that modulates the frequency, rate or extent of microtubule minus-end binding.
1902620	positive regulation of microtubule minus-end binding	P	Any process that activates or increases the frequency, rate or extent of microtubule minus-end binding.
1902621	actomyosin contractile ring disassembly	P	The disaggregation of an actomyosin contractile ring into its constituent components.
1902622	regulation of neutrophil migration	P	Any process that modulates the frequency, rate or extent of neutrophil migration.
1902623	negative regulation of neutrophil migration	P	Any process that stops, prevents or reduces the frequency, rate or extent of neutrophil migration.
1902624	positive regulation of neutrophil migration	P	Any process that activates or increases the frequency, rate or extent of neutrophil migration.
1902625	negative regulation of induction of conjugation with cellular fusion by negative regulation of transcription from RNA polymerase II promoter	P	A negative regulation of transcription from RNA polymerase II promoter that results in negative regulation of induction of conjugation with cellular fusion.
1902626	assembly of large subunit precursor of preribosome	P	The aggregation, arrangement and bonding together of a set of components to form the large subunit precursor of the preribosome.
1902627	regulation of assembly of large subunit precursor of preribosome	P	Any process that modulates the frequency, rate or extent of assembly of a large subunit precursor of preribosome.
1902628	positive regulation of assembly of large subunit precursor of preribosome	P	Any process that activates or increases the frequency, rate or extent of assembly of a large subunit precursor of preribosome.
1902629	regulation of mRNA stability involved in cellular response to UV	P	Any regulation of mRNA stability that is involved in cellular response to UV.
1902630	regulation of membrane hyperpolarization	P	Any process that modulates the frequency, rate or extent of membrane hyperpolarization.
1902631	negative regulation of membrane hyperpolarization	P	Any process that stops, prevents or reduces the frequency, rate or extent of membrane hyperpolarization.
1902632	positive regulation of membrane hyperpolarization	P	Any process that activates or increases the frequency, rate or extent of membrane hyperpolarization.
1902633	1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate metabolic process	P	The chemical reactions and pathways involving 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate.
1902634	1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate.
1902635	1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate.
1902636	kinociliary basal body	C	A ciliary basal body that is part of a kinocilium.
1902637	neural crest cell differentiation involved in thymus development	P	Any neural crest cell differentiation that is involved in thymus development.
1902638	neural crest cell differentiation involved in parathyroid gland development	P	Any neural crest cell differentiation that is involved in parathyroid gland development.
1902639	propan-2-ol metabolic process	P	The chemical reactions and pathways involving propan-2-ol.
1902640	propan-2-ol biosynthetic process	P	The chemical reactions and pathways resulting in the formation of propan-2-ol.
1902641	regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process	P	Any process that modulates the frequency, rate or extent of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process.
1902642	negative regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process.
1902643	positive regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process	P	Any process that activates or increases the frequency, rate or extent of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate catabolic process.
1902644	tertiary alcohol metabolic process	P	The chemical reactions and pathways involving tertiary alcohol.
1902645	tertiary alcohol biosynthetic process	P	The chemical reactions and pathways resulting in the formation of tertiary alcohol.
1902646	regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process	P	Any process that modulates the frequency, rate or extent of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process.
1902647	negative regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process.
1902648	positive regulation of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process.
1902649	regulation of histone H2A-H2B dimer displacement	P	Any process that modulates the frequency, rate or extent of histone H2A-H2B dimer displacement.
1902650	negative regulation of histone H2A-H2B dimer displacement	P	Any process that stops, prevents or reduces the frequency, rate or extent of histone H2A-H2B dimer displacement.
1902651	positive regulation of histone H2A-H2B dimer displacement	P	Any process that activates or increases the frequency, rate or extent of histone H2A-H2B dimer displacement.
1902652	secondary alcohol metabolic process	P	The chemical reactions and pathways involving secondary alcohol.
1902653	secondary alcohol biosynthetic process	P	The chemical reactions and pathways resulting in the formation of secondary alcohol.
1902654	aromatic primary alcohol metabolic process	P	The chemical reactions and pathways involving aromatic primary alcohol.
1902655	aromatic primary alcohol biosynthetic process	P	The chemical reactions and pathways resulting in the formation of aromatic primary alcohol.
1902656	calcium ion import into cytosol	P	The directed movement of calcium ion into a cytosol.
1902657	protein localization to prospore membrane	P	A process in which a protein is transported to, or maintained in, a location within a prospore membrane.
1902658	establishment of protein localization to prospore membrane	P	The directed movement of a protein to a specific location in a prospore membrane.
1902659	regulation of glucose mediated signaling pathway	P	Any process that modulates the frequency, rate or extent of glucose mediated signaling pathway.
1902660	negative regulation of glucose mediated signaling pathway	P	Any process that stops, prevents or reduces the frequency, rate or extent of glucose mediated signaling pathway.
1902661	positive regulation of glucose mediated signaling pathway	P	Any process that activates or increases the frequency, rate or extent of glucose mediated signaling pathway.
1902662	regulation of peptidyl-L-cysteine S-palmitoylation	P	Any process that modulates the frequency, rate or extent of peptidyl-L-cysteine S-palmitoylation.
1902663	negative regulation of peptidyl-L-cysteine S-palmitoylation	P	Any process that stops, prevents or reduces the frequency, rate or extent of peptidyl-L-cysteine S-palmitoylation.
1902664	positive regulation of peptidyl-L-cysteine S-palmitoylation	P	Any process that activates or increases the frequency, rate or extent of peptidyl-L-cysteine S-palmitoylation.
1902665	response to isobutanol	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an isobutanol stimulus.
1902666	protein localization to Mmi1 nuclear focus complex	P	A process in which a protein is transported to, or maintained in, a location within a Mmi1 nuclear focus complex.
1902667	regulation of axon guidance	P	Any process that modulates the frequency, rate or extent of axon guidance.
1902668	negative regulation of axon guidance	P	Any process that stops, prevents or reduces the frequency, rate or extent of axon guidance.
1902669	positive regulation of axon guidance	P	Any process that activates or increases the frequency, rate or extent of axon guidance.
1902670	carbon dioxide binding	F	Interacting selectively and non-covalently with carbon dioxide.
1902671	left anterior basal body	C	Any ciliary basal body that is part of a left anterior flagellum found in Giardia species (trophozoite stage).
1902672	right anterior basal body	C	Any ciliary basal body that is part of a right anterior flagellum found in Giardia species (trophozoite stage).
1902673	left posteriolateral basal body	C	Any ciliary basal body that is part of a left posteriolateral flagellum found in Giardia species (trophozoite stage).
1902674	right posteriolateral basal body	C	Any ciliary basal body that is part of a right posteriolateral flagellum found in Giardia species (trophozoite stage).
1902675	left ventral basal body	C	Any ciliary basal body that is part of a left ventral flagellum found in Giardia species (trophozoite stage).
1902676	right ventral basal body	C	Any ciliary basal body that is part of a right ventral flagellum found in Giardia species (trophozoite stage).
1902677	left caudal basal body	C	Any ciliary basal body that is part of a left caudal flagellum found in Giardia species (trophozoite stage).
1902678	right caudal basal body	C	Any ciliary basal body that is part of a right caudal flagellum found in Giardia species (trophozoite stage).
1902679	negative regulation of RNA biosynthetic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of RNA biosynthetic process.
1902680	positive regulation of RNA biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of RNA biosynthetic process.
1902681	regulation of replication fork arrest at rDNA repeats	P	Any process that modulates the frequency, rate or extent of replication fork arrest at rDNA repeats.
1902682	protein localization to nuclear pericentric heterochromatin	P	A process in which a protein is transported to, or maintained in, a location within a nuclear pericentric heterochromatin.
1902683	regulation of receptor localization to synapse	P	Any process that modulates the frequency, rate or extent of receptor localization to synapse.
1902684	negative regulation of receptor localization to synapse	P	Any process that stops, prevents or reduces the frequency, rate or extent of receptor localization to synapse.
1902685	positive regulation of receptor localization to synapse	P	Any process that activates or increases the frequency, rate or extent of receptor localization to synapse.
1902686	mitochondrial outer membrane permeabilization involved in programmed cell death	P	The process by which the mitochondrial outer membrane becomes permeable to the passing of proteins and other molecules from the intermembrane space to the cytosol as part of a programmed cell death process.
1902687	glucosidase complex	C	A protein complex which is capable of glucosidase activity.
1902688	regulation of NAD metabolic process	P	Any process that modulates the frequency, rate or extent of NAD metabolic process.
1902689	negative regulation of NAD metabolic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of NAD metabolic process.
1902690	positive regulation of NAD metabolic process	P	Any process that activates or increases the frequency, rate or extent of NAD metabolic process.
1902691	respiratory basal cell differentiation	P	The process in which a relatively unspecialized cell acquires the specialized features of a respiratory basal cell.
1902692	regulation of neuroblast proliferation	P	Any process that modulates the frequency, rate or extent of neuroblast proliferation.
1902693	superoxide dismutase complex	C	A protein complex which is capable of superoxide dismutase activity.
1902694	superoxide dismutase copper chaperone complex	C	A protein complex which is capable of superoxide dismutase copper chaperone activity.
1902695	metallochaperone complex	C	A protein complex which is capable of metallochaperone activity.
1902696	glycine catabolic process to isobutanol	P	The chemical reactions and pathways resulting in the breakdown of glycine to isobutanol.
1902697	valine catabolic process to isobutanol	P	The chemical reactions and pathways resulting in the breakdown of valine to isobutanol.
1902698	pentose catabolic process to butyrate	P	The chemical reactions and pathways resulting in the breakdown of pentose to butyrate.
1902699	pentose catabolic process to acetate	P	The chemical reactions and pathways resulting in the breakdown of pentose to acetate.
1902700	pentose catabolic process to butan-1-ol	P	The chemical reactions and pathways resulting in the breakdown of pentose to butan-1-ol.
1902701	pentose catabolic process to propan-2-ol	P	The chemical reactions and pathways resulting in the breakdown of pentose to propan-2-ol.
1902702	hexose catabolic process to propan-2-ol	P	The chemical reactions and pathways resulting in the breakdown of hexose to propan-2-ol.
1902703	hexose catabolic process to butan-1-ol	P	The chemical reactions and pathways resulting in the breakdown of hexose to butan-1-ol.
1902704	hexose catabolic process to acetone	P	The chemical reactions and pathways resulting in the breakdown of hexose to acetone.
1902705	hexose catabolic process to butyrate	P	The chemical reactions and pathways resulting in the breakdown of hexose to butyrate.
1902706	hexose catabolic process to acetate	P	The chemical reactions and pathways resulting in the breakdown of hexose to acetate.
1902707	hexose catabolic process to ethanol	P	The chemical reactions and pathways resulting in the breakdown of hexose to ethanol.
1902708	response to plumbagin	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a plumbagin stimulus.
1902709	cellular response to plumbagin	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a plumbagin stimulus.
1902710	GABA receptor complex	C	A protein complex which is capable of GABA receptor activity. Upon binding of gamma-aminobutyric acid (GABA) it transmits the signal from one side of the membrane to the other to initiate a change in cell activity. Major inhibitory receptor in vertebrate brain. Also found in other vertebrate tissues, invertebrates and possibly in plants. Effective benzodiazepine receptor.
1902711	GABA-A receptor complex	C	A protein complex which is capable of GABA-A receptor activity. In human, it is usually composed of either two alpha, two beta and one gamma chain of the GABA-A receptor subunits or 5 chains of the GABA-A receptor subunits rho1-3 (formally known as GABA-C receptor).
1902712	G-protein coupled GABA receptor complex	C	A protein complex which is capable of G-protein coupled GABA receptor activity. In human, it is usually a heterodimer composed of GABA-B receptor subunits 1 and 2.
1902713	regulation of interferon-gamma secretion	P	Any process that modulates the frequency, rate or extent of interferon-gamma secretion.
1902714	negative regulation of interferon-gamma secretion	P	Any process that stops, prevents or reduces the frequency, rate or extent of interferon-gamma secretion.
1902715	positive regulation of interferon-gamma secretion	P	Any process that activates or increases the frequency, rate or extent of interferon-gamma secretion.
1902716	cell cortex of growing cell tip	C	Any cell cortex that is part of a growing cell tip.
1902721	negative regulation of prolactin secretion	P	Any process that stops, prevents or reduces the frequency, rate or extent of prolactin secretion.
1902722	positive regulation of prolactin secretion	P	Any process that activates or increases the frequency, rate or extent of prolactin secretion.
1902723	negative regulation of skeletal muscle satellite cell proliferation	P	Any process that stops, prevents or reduces the frequency, rate or extent of satellite cell proliferation.
1902724	positive regulation of skeletal muscle satellite cell proliferation	P	Any process that activates or increases the frequency, rate or extent of skeletal muscle satellite cell proliferation.
1902725	negative regulation of satellite cell differentiation	P	Any process that stops, prevents or reduces the frequency, rate or extent of satellite cell differentiation.
1902726	positive regulation of skeletal muscle satellite cell differentiation	P	Any process that activates or increases the frequency, rate or extent of satellite cell differentiation.
1902727	negative regulation of growth factor dependent skeletal muscle satellite cell proliferation	P	Any process that stops, prevents or reduces the frequency, rate or extent of satellite cell proliferation; dependent on specific growth factor activity such as fibroblast growth factors and transforming growth factor beta.
1902728	positive regulation of growth factor dependent skeletal muscle satellite cell proliferation	P	Any process that activates or increases the frequency, rate or extent of satellite cell proliferation; dependent on specific growth factor activity such as fibroblast growth factors and transforming growth factor beta.
1902729	negative regulation of proteoglycan biosynthetic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteoglycans, any glycoprotein in which the carbohydrate units are glycosaminoglycans.
1902730	positive regulation of proteoglycan biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteoglycans, any glycoprotein in which the carbohydrate units are glycosaminoglycans.
1902731	negative regulation of chondrocyte proliferation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of the multiplication or reproduction of chondrocytes by cell division, resulting in the expansion of their population. A chondrocyte is a polymorphic cell that forms cartilage.
1902732	positive regulation of chondrocyte proliferation	P	Any process that increases the frequency, rate or extent of the multiplication or reproduction of chondrocytes by cell division, resulting in the expansion of their population. A chondrocyte is a polymorphic cell that forms cartilage.
1902733	regulation of growth plate cartilage chondrocyte differentiation	P	Any process that modulates the rate, frequency, or extent of the process in which a chondroblast acquires specialized structural and/or functional features of a chondrocyte that will contribute to the growth of a bone. A chondrocyte is a polymorphic cell that forms cartilage
1902734	regulation of receptor-mediated virion attachment to host cell	P	Any process that modulates the frequency, rate or extent of receptor-mediated virion attachment to host cell.
1902735	negative regulation of receptor-mediated virion attachment to host cell	P	Any process that stops, prevents or reduces the frequency, rate or extent of receptor-mediated virion attachment to host cell.
1902736	positive regulation of receptor-mediated virion attachment to host cell	P	Any process that activates or increases the frequency, rate or extent of receptor-mediated virion attachment to host cell.
1902737	dendritic filopodium	C	A small, membranous protrusion found primarily on dendritic stretches of developing neurons. May receive synaptic input, and can develop into dendritic spines.
1902738	regulation of chondrocyte differentiation involved in endochondral bone morphogenesis	P	Any process that modulates the rate, frequency, or extent of the process in which a chondroblast acquires specialized structural and/or functional features of a chondrocyte that will contribute to the development of a bone. A chondrocyte is a polymorphic cell that forms cartilage.
1902739	regulation of interferon-alpha secretion	P	Any process that modulates the frequency, rate or extent of interferon-alpha secretion.
1902740	negative regulation of interferon-alpha secretion	P	Any process that stops, prevents or reduces the frequency, rate or extent of interferon-alpha secretion.
1902741	positive regulation of interferon-alpha secretion	P	Any process that activates or increases the frequency, rate or extent of interferon-alpha secretion.
1902742	apoptotic process involved in development	P	Any apoptotic process that is involved in anatomical structure development.
1902743	regulation of lamellipodium organization	P	Any process that modulates the frequency, rate or extent of lamellipodium organization.
1902744	negative regulation of lamellipodium organization	P	Any process that stops, prevents or reduces the frequency, rate or extent of lamellipodium organization.
1902745	positive regulation of lamellipodium organization	P	Any process that activates or increases the frequency, rate or extent of lamellipodium organization.
1902746	regulation of lens fiber cell differentiation	P	Any process that modulates the frequency, rate or extent of lens fiber cell differentiation.
1902747	negative regulation of lens fiber cell differentiation	P	Any process that stops, prevents or reduces the frequency, rate or extent of lens fiber cell differentiation.
1902748	positive regulation of lens fiber cell differentiation	P	Any process that activates or increases the frequency, rate or extent of lens fiber cell differentiation.
1902749	regulation of cell cycle G2/M phase transition	P	Any process that modulates the frequency, rate or extent of cell cycle G2/M phase transition.
1902750	negative regulation of cell cycle G2/M phase transition	P	Any process that stops, prevents or reduces the frequency, rate or extent of cell cycle G2/M phase transition.
1902751	positive regulation of cell cycle G2/M phase transition	P	Any process that activates or increases the frequency, rate or extent of cell cycle G2/M phase transition.
1902752	regulation of renal amino acid absorption	P	Any process that modulates the frequency, rate or extent of renal amino acid absorption.
1902753	negative regulation of renal amino acid absorption	P	Any process that stops, prevents or reduces the frequency, rate or extent of renal amino acid absorption.
1902754	positive regulation of renal amino acid absorption	P	Any process that activates or increases the frequency, rate or extent of renal amino acid absorption.
1902755	sulfurated eukaryotic molybdenum cofactor(2-) metabolic process	P	The chemical reactions and pathways involving sulfurated eukaryotic molybdenum cofactor(2-).
1902756	sulfurated eukaryotic molybdenum cofactor(2-) biosynthetic process	P	The chemical reactions and pathways resulting in the formation of sulfurated eukaryotic molybdenum cofactor(2-).
1902757	bis(molybdopterin guanine dinucleotide)molybdenum metabolic process	P	The chemical reactions and pathways involving bis(molybdopterin guanine dinucleotide)molybdenum.
1902758	bis(molybdopterin guanine dinucleotide)molybdenum biosynthetic process	P	The chemical reactions and pathways resulting in the formation of bis(molybdopterin guanine dinucleotide)molybdenum.
1902759	Mo(VI)-molybdopterin cytosine dinucleotide metabolic process	P	The chemical reactions and pathways involving Mo(VI)-molybdopterin cytosine dinucleotide.
1902760	Mo(VI)-molybdopterin cytosine dinucleotide biosynthetic process	P	The chemical reactions and pathways resulting in the formation of Mo(VI)-molybdopterin cytosine dinucleotide.
1902761	positive regulation of chondrocyte development	P	Any process that activates or increases the frequency, rate or extent of chondrocyte development.
1902762	regulation of embryonic skeletal joint development	P	Any process that modulates the frequency, rate or extent of embryonic skeletal joint development.
1902763	negative regulation of embryonic skeletal joint development	P	Any process that stops, prevents or reduces the frequency, rate or extent of embryonic skeletal joint development.
1902764	positive regulation of embryonic skeletal joint development	P	Any process that activates or increases the frequency, rate or extent of embryonic skeletal joint development.
1902765	L-arginine import into cell	P	The directed movement of L-arginine from outside of a cell into the cytoplasmic compartment. This may occur via transport across the plasma membrane or via endocytosis.
1902766	skeletal muscle satellite cell migration	P	The orderly movement of a skeletal muscle satellite cell from one site to another. Migration of these cells is a key step in the process of growth and repair of skeletal muscle cells.
1902767	isoprenoid biosynthetic process via mevalonate	P	The chemical reactions and pathways resulting in the formation of isoprenoid via mevalonate.
1902768	isoprenoid biosynthetic process via 1-deoxy-D-xylulose 5-phosphate	P	The chemical reactions and pathways resulting in the formation of isoprenoid via 1-deoxy-D-xylulose 5-phosphate.
1902769	regulation of choline O-acetyltransferase activity	P	Any process that modulates the frequency, rate or extent of choline O-acetyltransferase activity.
1902770	negative regulation of choline O-acetyltransferase activity	P	Any process that stops, prevents or reduces the frequency, rate or extent of choline O-acetyltransferase activity.
1902771	positive regulation of choline O-acetyltransferase activity	P	Any process that activates or increases the frequency, rate or extent of choline O-acetyltransferase activity.
1902772	positive regulation of phosphorelay signal transduction system involved in hydrogen peroxide mediated signaling pathway	P	Any positive regulation of phosphorelay signal transduction system that is involved in hydrogen peroxide mediated signaling pathway.
1902773	GTPase activator complex	C	A protein complex which is capable of GTPase activator activity.
1902774	late endosome to lysosome transport	P	The directed movement of substances from late endosome to lysosome.
1902775	mitochondrial large ribosomal subunit assembly	P	The aggregation, arrangement and bonding together of a set of components to form a mitochondrial large ribosomal subunit.
1902776	6-sulfoquinovose(1-) metabolic process	P	The chemical reactions and pathways involving 6-sulfoquinovose(1-).
1902777	6-sulfoquinovose(1-) catabolic process	P	The chemical reactions and pathways resulting in the breakdown of 6-sulfoquinovose(1-).
1902778	response to alkane	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alkane stimulus.
1902779	cellular response to alkane	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an alkane stimulus.
1902780	response to nonane	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nonane stimulus.
1902781	cellular response to nonane	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nonane stimulus.
1902782	response to decane	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a decane stimulus.
1902783	cellular response to decane	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a decane stimulus.
1902784	response to undecane	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an undecane stimulus.
1902785	cellular response to undecane	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an undecane stimulus.
1902786	response to dodecane	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dodecane stimulus.
1902787	cellular response to dodecane	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dodecane stimulus.
1902788	response to isooctane	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an isooctane stimulus.
1902789	cellular response to isooctane	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an isooctane stimulus.
1902790	undecan-2-one metabolic process	P	The chemical reactions and pathways involving undecan-2-one.
1902791	undecan-2-one biosynthetic process	P	The chemical reactions and pathways resulting in the formation of undecan-2-one.
1902792	pyrroline-5-carboxylate reductase complex	C	A protein complex which is capable of pyrroline-5-carboxylate reductase activity.
1902793	glutamate decarboxylase complex	C	A protein complex which is capable of glutamate decarboxylase activity.
1902794	heterochromatin island assembly	P	The aggregation, arrangement and bonding together of a set of components to form a heterochromatin island.
1902795	heterochromatin domain assembly	P	The aggregation, arrangement and bonding together of a set of components to form a heterochromatin domain.
1902796	regulation of snoRNA processing	P	Any process that modulates the frequency, rate or extent of snoRNA processing.
1902797	negative regulation of snoRNA processing	P	Any process that stops, prevents or reduces the frequency, rate or extent of snoRNA processing.
1902798	positive regulation of snoRNA processing	P	Any process that activates or increases the frequency, rate or extent of snoRNA processing.
1902799	regulation of phosphodiesterase I activity	P	Any process that modulates the frequency, rate or extent of phosphodiesterase I activity.
1902800	positive regulation of phosphodiesterase I activity	P	Any process that activates or increases the frequency, rate or extent of phosphodiesterase I activity.
1902801	regulation of heterochromatin island assembly	P	Any process that modulates the frequency, rate or extent of heterochromatin island assembly.
1902802	regulation of heterochromatin domain assembly	P	Any process that modulates the frequency, rate or extent of heterochromatin domain assembly.
1902803	regulation of synaptic vesicle transport	P	Any process that modulates the frequency, rate or extent of synaptic vesicle transport.
1902804	negative regulation of synaptic vesicle transport	P	Any process that stops, prevents or reduces the frequency, rate or extent of synaptic vesicle transport.
1902805	positive regulation of synaptic vesicle transport	P	Any process that activates or increases the frequency, rate or extent of synaptic vesicle transport.
1902806	regulation of cell cycle G1/S phase transition	P	Any process that modulates the frequency, rate or extent of cell cycle G1/S phase transition.
1902807	negative regulation of cell cycle G1/S phase transition	P	Any process that stops, prevents or reduces the frequency, rate or extent of cell cycle G1/S phase transition.
1902808	positive regulation of cell cycle G1/S phase transition	P	Any process that activates or increases the frequency, rate or extent of cell cycle G1/S phase transition.
1902809	regulation of skeletal muscle fiber differentiation	P	Any process that modulates the frequency, rate or extent of skeletal muscle fiber differentiation.
1902810	negative regulation of skeletal muscle fiber differentiation	P	Any process that stops, prevents or reduces the frequency, rate or extent of skeletal muscle fiber differentiation.
1902811	positive regulation of skeletal muscle fiber differentiation	P	Any process that activates or increases the frequency, rate or extent of skeletal muscle fiber differentiation.
1902812	regulation of BMP signaling pathway involved in determination of lateral mesoderm left/right asymmetry	P	Any process that modulates the frequency, rate or extent of BMP signaling pathway involved in determination of lateral mesoderm left/right asymmetry.
1902813	negative regulation of BMP signaling pathway involved in determination of lateral mesoderm left/right asymmetry	P	Any process that stops, prevents or reduces the frequency, rate or extent of BMP signaling pathway involved in determination of lateral mesoderm left/right asymmetry.
1902814	positive regulation of BMP signaling pathway involved in determination of lateral mesoderm left/right asymmetry	P	Any process that activates or increases the frequency, rate or extent of BMP signaling pathway involved in determination of lateral mesoderm left/right asymmetry.
1902815	N,N'-diacetylchitobiose import	P	The directed movement of N,N'-diacetylchitobiose into a cell or organelle.
1902816	regulation of protein localization to microtubule	P	Any process that modulates the frequency, rate or extent of protein localization to microtubule.
1902817	negative regulation of protein localization to microtubule	P	Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to microtubule.
1902818	ethyl acetate metabolic process	P	The chemical reactions and pathways involving ethyl acetate.
1902819	ethyl acetate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of ethyl acetate.
1902820	1-undecene metabolic process	P	The chemical reactions and pathways involving 1-undecene.
1902821	1-undecene biosynthetic process	P	The chemical reactions and pathways resulting in the formation of 1-undecene.
1902822	regulation of late endosome to lysosome transport	P	Any process that modulates the frequency, rate or extent of late endosome to lysosome transport.
1902823	negative regulation of late endosome to lysosome transport	P	Any process that stops, prevents or reduces the frequency, rate or extent of late endosome to lysosome transport.
1902824	positive regulation of late endosome to lysosome transport	P	Any process that activates or increases the frequency, rate or extent of late endosome to lysosome transport.
1902825	proline import into cell	P	The directed movement of proline from outside of a cell into the cytoplasmic compartment. This may occur via transport across the plasma membrane or via endocytosis.
1902826	regulation of L-arginine import into cell	P	Any process that modulates the frequency, rate or extent of L-arginine import into cell.
1902827	negative regulation of L-arginine import into cell	P	Any process that stops, prevents or reduces the frequency, rate or extent of L-arginine import into cell.
1902828	positive regulation of L-arginine import into cell	P	Any process that activates or increases the frequency, rate or extent of L-arginine import into cell.
1902829	regulation of spinal cord association neuron differentiation	P	Any process that modulates the frequency, rate or extent of spinal cord association neuron differentiation.
1902830	negative regulation of spinal cord association neuron differentiation	P	Any process that stops, prevents or reduces the frequency, rate or extent of spinal cord association neuron differentiation.
1902831	positive regulation of spinal cord association neuron differentiation	P	Any process that activates or increases the frequency, rate or extent of spinal cord association neuron differentiation.
1902832	negative regulation of cell proliferation in dorsal spinal cord	P	Any process that stops, prevents or reduces the frequency, rate or extent of cell proliferation in dorsal spinal cord.
1902833	positive regulation of cell proliferation in dorsal spinal cord	P	Any process that activates or increases the frequency, rate or extent of cell proliferation in dorsal spinal cord.
1902834	regulation of proline import into cell	P	Any process that modulates the frequency, rate or extent of proline import into cell.
1902835	negative regulation of proline import into cell	P	Any process that stops, prevents or reduces the frequency, rate or extent of proline import into cell.
1902836	positive regulation of proline import into cell	P	Any process that activates or increases the frequency, rate or extent of proline import into cell.
1902837	amino acid import into cell	P	The directed movement of amino acids from outside of a cell into the cytoplasmic compartment. This may occur via transport across the plasma membrane or via endocytosis.
1902838	regulation of nuclear migration along microtubule	P	Any process that modulates the frequency, rate or extent of nuclear migration along microtubule.
1902839	negative regulation of nuclear migration along microtubule	P	Any process that stops, prevents or reduces the frequency, rate or extent of nuclear migration along microtubule.
1902840	positive regulation of nuclear migration along microtubule	P	Any process that activates or increases the frequency, rate or extent of nuclear migration along microtubule.
1902841	regulation of netrin-activated signaling pathway	P	Any process that modulates the frequency, rate or extent of netrin-activated signaling pathway.
1902842	negative regulation of netrin-activated signaling pathway	P	Any process that stops, prevents or reduces the frequency, rate or extent of netrin-activated signaling pathway.
1902843	positive regulation of netrin-activated signaling pathway	P	Any process that activates or increases the frequency, rate or extent of netrin-activated signaling pathway.
1902844	positive regulation of spinal cord association neuron differentiation by negative regulation of canonical Wnt signaling pathway	P	A negative regulation of canonical Wnt signaling pathway that results in positive regulation of spinal cord association neuron differentiation.
1902845	negative regulation of mitotic spindle elongation	P	Any process that stops, prevents or reduces the frequency, rate or extent of mitotic spindle elongation.
1902846	positive regulation of mitotic spindle elongation	P	Any process that activates or increases the frequency, rate or extent of mitotic spindle elongation.
1902847	regulation of neuronal signal transduction	P	Any process that modulates the frequency, rate or extent of neuronal signal transduction.
1902848	negative regulation of neuronal signal transduction	P	Any process that stops, prevents or reduces the frequency, rate or extent of neuronal signal transduction.
1902849	positive regulation of neuronal signal transduction	P	Any process that activates or increases the frequency, rate or extent of neuronal signal transduction.
1902850	microtubule cytoskeleton organization involved in mitosis	P	Any microtubule cytoskeleton organization that is involved in mitosis.
1902852	regulation of nuclear migration during mitotic telophase	P	Any process that modulates the frequency, rate or extent of nuclear migration during mitotic telophase.
1902853	negative regulation of nuclear migration during mitotic telophase	P	Any process that stops, prevents or reduces the frequency, rate or extent of nuclear migration during mitotic telophase.
1902854	positive regulation of nuclear migration during mitotic telophase	P	Any process that activates or increases the frequency, rate or extent of nuclear migration during mitotic telophase.
1902855	regulation of non-motile cilium assembly	P	Any process that modulates the frequency, rate or extent of non-motile cilium assembly.
1902856	negative regulation of non-motile cilium assembly	P	Any process that stops, prevents or reduces the frequency, rate or extent of non-motile cilium assembly.
1902857	positive regulation of non-motile cilium assembly	P	Any process that activates or increases the frequency, rate or extent of non-motile cilium assembly.
1902858	propionyl-CoA metabolic process	P	The chemical reactions and pathways involving propionyl-CoA.
1902859	propionyl-CoA catabolic process	P	The chemical reactions and pathways resulting in the breakdown of propionyl-CoA.
1902860	propionyl-CoA biosynthetic process	P	The chemical reactions and pathways resulting in the formation of propionyl-CoA.
1902861	copper ion import into cell	P	The directed movement of copper ions from outside of a cell into the cytoplasmic compartment. This may occur via transport across the plasma membrane or via endocytosis.
1902863	regulation of embryonic camera-type eye development	P	Any process that modulates the frequency, rate or extent of embryonic camera-type eye development.
1902864	negative regulation of embryonic camera-type eye development	P	Any process that stops, prevents or reduces the frequency, rate or extent of embryonic camera-type eye development.
1902865	positive regulation of embryonic camera-type eye development	P	Any process that activates or increases the frequency, rate or extent of embryonic camera-type eye development.
1902866	regulation of retina development in camera-type eye	P	Any process that modulates the frequency, rate or extent of retina development in camera-type eye.
1902867	negative regulation of retina development in camera-type eye	P	Any process that stops, prevents or reduces the frequency, rate or extent of retina development in camera-type eye.
1902868	positive regulation of retina development in camera-type eye	P	Any process that activates or increases the frequency, rate or extent of retina development in camera-type eye.
1902869	regulation of amacrine cell differentiation	P	Any process that modulates the frequency, rate or extent of amacrine cell differentiation.
1902870	negative regulation of amacrine cell differentiation	P	Any process that stops, prevents or reduces the frequency, rate or extent of amacrine cell differentiation.
1902871	positive regulation of amacrine cell differentiation	P	Any process that activates or increases the frequency, rate or extent of amacrine cell differentiation.
1902872	regulation of horizontal cell localization	P	Any process that modulates the frequency, rate or extent of horizontal cell localization.
1902873	negative regulation of horizontal cell localization	P	Any process that stops, prevents or reduces the frequency, rate or extent of horizontal cell localization.
1902874	positive regulation of horizontal cell localization	P	Any process that activates or increases the frequency, rate or extent of horizontal cell localization.
1902875	regulation of embryonic pattern specification	P	Any process that modulates the frequency, rate or extent of embryonic pattern specification.
1902876	negative regulation of embryonic pattern specification	P	Any process that stops, prevents or reduces the frequency, rate or extent of embryonic pattern specification.
1902877	positive regulation of embryonic pattern specification	P	Any process that activates or increases the frequency, rate or extent of embryonic pattern specification.
1902878	regulation of BMP signaling pathway involved in spinal cord association neuron specification	P	Any process that modulates the frequency, rate or extent of BMP signaling pathway involved in spinal cord association neuron specification.
1902879	negative regulation of BMP signaling pathway involved in spinal cord association neuron specification	P	Any process that stops, prevents or reduces the frequency, rate or extent of BMP signaling pathway involved in spinal cord association neuron specification.
1902880	positive regulation of BMP signaling pathway involved in spinal cord association neuron specification	P	Any process that activates or increases the frequency, rate or extent of BMP signaling pathway involved in spinal cord association neuron specification.
1902882	regulation of response to oxidative stress	P	Any process that modulates the frequency, rate or extent of response to oxidative stress.
1902883	negative regulation of response to oxidative stress	P	Any process that stops, prevents or reduces the frequency, rate or extent of response to oxidative stress.
1902884	positive regulation of response to oxidative stress	P	Any process that activates or increases the frequency, rate or extent of response to oxidative stress.
1902885	regulation of proteasome-activating ATPase activity	P	Any process that modulates the frequency, rate or extent of proteasome-activating ATPase activity.
1902886	negative regulation of proteasome-activating ATPase activity	P	Any process that stops, prevents or reduces the frequency, rate or extent of proteasome-activating ATPase activity.
1902887	positive regulation of proteasome-activating ATPase activity	P	Any process that activates or increases the frequency, rate or extent of proteasome-activating ATPase activity.
1902888	protein localization to astral microtubule	P	A process in which a protein is transported to, or maintained in, a location within an astral microtubule.
1902889	protein localization to spindle microtubule	P	A process in which a protein is transported to, or maintained in, a location within a spindle microtubule.
1902890	regulation of root hair elongation	P	Any process that modulates the frequency, rate or extent of root hair elongation.
1902891	negative regulation of root hair elongation	P	Any process that stops, prevents or reduces the frequency, rate or extent of root hair elongation.
1902892	positive regulation of root hair elongation	P	Any process that activates or increases the frequency, rate or extent of root hair elongation.
1902893	regulation of pri-miRNA transcription from RNA polymerase II promoter	P	Any process that modulates the frequency, rate or extent of pri-miRNA transcription from RNA polymerase II promoter.
1902894	negative regulation of pri-miRNA transcription from RNA polymerase II promoter	P	Any process that stops, prevents or reduces the frequency, rate or extent of pri-miRNA transcription from RNA polymerase II promoter.
1902895	positive regulation of pri-miRNA transcription from RNA polymerase II promoter	P	Any process that activates or increases the frequency, rate or extent of pri-miRNA transcription from RNA polymerase II promoter.
1902896	terminal web assembly	P	The aggregation, arrangement and bonding together of a set of components to form a terminal web.
1902897	regulation of postsynaptic density protein 95 clustering	P	Any process that modulates the frequency, rate or extent of postsynaptic density protein 95 clustering.
1902898	fatty acid methyl ester metabolic process	P	The chemical reactions and pathways involving fatty acid methyl ester.
1902899	fatty acid methyl ester biosynthetic process	P	The chemical reactions and pathways resulting in the formation of fatty acid methyl ester.
1902900	gut granule assembly	P	The aggregation, arrangement and bonding together of a set of components to form a gut granule.
1902901	positive regulation of transcription from RNA polymerase II promoter involved in stress response to cadmium ion	P	Any positive regulation of transcription from RNA polymerase II promoter that is involved in stress response to cadmium ion.
1902902	negative regulation of autophagosome assembly	P	Any process that stops, prevents or reduces the frequency, rate or extent of autophagosome assembly.
1902903	regulation of supramolecular fiber organization	P	Any process that modulates the frequency, rate or extent of supramolecular fiber organization.
1902904	negative regulation of supramolecular fiber organization	P	Any process that stops, prevents or reduces the frequency, rate or extent of fibril organization.
1902905	positive regulation of supramolecular fiber organization	P	Any process that activates or increases the frequency, rate or extent of supramolecular fiber organization.
1902906	proteasome storage granule assembly	P	The aggregation, arrangement and bonding together of a set of components to form a proteasome storage granule.
1902907	proteasome storage granule disassembly	P	The disaggregation of a proteasome storage granule into its constituent components.
1902908	regulation of melanosome transport	P	Any process that modulates the frequency, rate or extent of melanosome transport.
1902909	negative regulation of melanosome transport	P	Any process that stops, prevents or reduces the frequency, rate or extent of melanosome transport.
1902910	positive regulation of melanosome transport	P	Any process that activates or increases the frequency, rate or extent of melanosome transport.
1902911	protein kinase complex	C	A protein complex which is capable of protein kinase activity.
1902912	pyruvate kinase complex	C	A protein complex which is capable of pyruvate kinase activity.
1902913	positive regulation of neuroepithelial cell differentiation	P	Any process that activates or increases the frequency, rate or extent of neuroepithelial cell differentiation.
1902914	regulation of protein polyubiquitination	P	Any process that modulates the frequency, rate or extent of protein polyubiquitination.
1902915	negative regulation of protein polyubiquitination	P	Any process that stops, prevents or reduces the frequency, rate or extent of protein polyubiquitination.
1902916	positive regulation of protein polyubiquitination	P	Any process that activates or increases the frequency, rate or extent of protein polyubiquitination.
1902917	positive regulation of mating projection assembly	P	Any process that activates or increases the frequency, rate or extent of mating projection assembly.
1902918	poly(5-hydroxyvalerate) metabolic process	P	The chemical reactions and pathways involving poly(5-hydroxyvalerate).
1902919	poly(5-hydroxyvalerate) biosynthetic process	P	The chemical reactions and pathways resulting in the formation of poly(5-hydroxyvalerate).
1902920	poly(hydroxyvalerate) metabolic process	P	The chemical reactions and pathways involving poly(hydroxyvalerate).
1902921	poly(hydroxyvalerate) biosynthetic process	P	The chemical reactions and pathways resulting in the formation of poly(hydroxyvalerate).
1902922	poly(3-hydroxyvalerate) metabolic process	P	The chemical reactions and pathways involving poly(3-hydroxyvalerate).
1902923	poly(3-hydroxyvalerate) biosynthetic process	P	The chemical reactions and pathways resulting in the formation of poly(3-hydroxyvalerate).
1902924	poly(hydroxyalkanoate) biosynthetic process from glucose	P	The chemical reactions and pathways resulting in the formation of poly(hydroxyalkanoate) from glucose.
1902925	poly(hydroxyalkanoate) biosynthetic process from fatty acid	P	The chemical reactions and pathways resulting in the formation of poly(hydroxyalkanoate) from fatty acid.
1902926	inulin metabolic process	P	The chemical reactions and pathways involving inulin.
1902927	inulin catabolic process	P	The chemical reactions and pathways resulting in the breakdown of inulin.
1902928	inulin biosynthetic process	P	The chemical reactions and pathways resulting in the formation of inulin.
1902929	plasma membrane of growing cell tip	C	Any plasma membrane part that is part of a growing cell tip.
1902930	regulation of alcohol biosynthetic process	P	Any process that modulates the frequency, rate or extent of alcohol biosynthetic process.
1902931	negative regulation of alcohol biosynthetic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of alcohol biosynthetic process.
1902932	positive regulation of alcohol biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of alcohol biosynthetic process.
1902933	isopentenol metabolic process	P	The chemical reactions and pathways involving isopentenol.
1902934	isopentenol biosynthetic process	P	The chemical reactions and pathways resulting in the formation of isopentenol.
1902935	protein localization to septin ring	P	A process in which a protein is transported to, or maintained in, a location within a septin ring.
1902936	phosphatidylinositol bisphosphate binding	F	Interacting selectively and non-covalently with phosphatidylinositol bisphosphate.
1902937	inward rectifier potassium channel complex	C	A protein complex which is capable of inward rectifier potassium channel activity.
1902938	regulation of intracellular calcium activated chloride channel activity	P	Any process that modulates the frequency, rate or extent of intracellular calcium activated chloride channel activity.
1902939	negative regulation of intracellular calcium activated chloride channel activity	P	Any process that stops, prevents or reduces the frequency, rate or extent of intracellular calcium activated chloride channel activity.
1902940	positive regulation of intracellular calcium activated chloride channel activity	P	Any process that activates or increases the frequency, rate or extent of intracellular calcium activated chloride channel activity.
1902941	regulation of voltage-gated chloride channel activity	P	Any process that modulates the frequency, rate or extent of voltage-gated chloride channel activity.
1902942	negative regulation of voltage-gated chloride channel activity	P	Any process that stops, prevents or reduces the frequency, rate or extent of voltage-gated chloride channel activity.
1902943	positive regulation of voltage-gated chloride channel activity	P	Any process that activates or increases the frequency, rate or extent of voltage-gated chloride channel activity.
1902944	aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process	F	Any aspartic-type endopeptidase activity that is involved in amyloid precursor protein catabolic process.
1902945	metalloendopeptidase activity involved in amyloid precursor protein catabolic process	F	Any metalloendopeptidase activity that is involved in amyloid precursor protein catabolic process.
1902946	protein localization to early endosome	P	A process in which a protein is transported to, or maintained in, a location within an early endosome.
1902947	regulation of tau-protein kinase activity	P	Any process that modulates the frequency, rate or extent of tau-protein kinase activity.
1902948	negative regulation of tau-protein kinase activity	P	Any process that stops, prevents or reduces the frequency, rate or extent of tau-protein kinase activity.
1902949	positive regulation of tau-protein kinase activity	P	Any process that activates or increases the frequency, rate or extent of tau-protein kinase activity.
1902950	regulation of dendritic spine maintenance	P	Any process that modulates the frequency, rate or extent of dendritic spine maintenance.
1902951	negative regulation of dendritic spine maintenance	P	Any process that stops, prevents or reduces the frequency, rate or extent of dendritic spine maintenance.
1902952	positive regulation of dendritic spine maintenance	P	Any process that activates or increases the frequency, rate or extent of dendritic spine maintenance.
1902953	positive regulation of ER to Golgi vesicle-mediated transport	P	Any process that activates or increases the frequency, rate or extent of ER to Golgi vesicle-mediated transport.
1902954	regulation of early endosome to recycling endosome transport	P	Any process that modulates the frequency, rate or extent of early endosome to recycling endosome transport.
1902955	positive regulation of early endosome to recycling endosome transport	P	Any process that activates or increases the frequency, rate or extent of early endosome to recycling endosome transport.
1902956	regulation of mitochondrial electron transport, NADH to ubiquinone	P	Any process that modulates the frequency, rate or extent of mitochondrial electron transport, NADH to ubiquinone.
1902957	negative regulation of mitochondrial electron transport, NADH to ubiquinone	P	Any process that stops, prevents or reduces the frequency, rate or extent of mitochondrial electron transport, NADH to ubiquinone.
1902958	positive regulation of mitochondrial electron transport, NADH to ubiquinone	P	Any process that activates or increases the frequency, rate or extent of mitochondrial electron transport, NADH to ubiquinone.
1902959	regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process	P	Any process that modulates the frequency, rate or extent of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process.
1902960	negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process.
1902961	positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process	P	Any process that activates or increases the frequency, rate or extent of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process.
1902962	regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process	P	Any process that modulates the frequency, rate or extent of metalloendopeptidase activity involved in amyloid precursor protein catabolic process.
1902963	negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of metalloendopeptidase activity involved in amyloid precursor protein catabolic process.
1902964	positive regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process	P	Any process that activates or increases the frequency, rate or extent of metalloendopeptidase activity involved in amyloid precursor protein catabolic process.
1902965	regulation of protein localization to early endosome	P	Any process that modulates the frequency, rate or extent of protein localization to early endosome.
1902966	positive regulation of protein localization to early endosome	P	Any process that activates or increases the frequency, rate or extent of protein localization to early endosome.
1902967	protein localization to mitotic spindle midzone	P	A process in which a protein is transported to, or maintained in, a location within a mitotic spindle midzone.
1902969	mitotic DNA replication	P	Any nuclear DNA replication that is involved in a mitotic cell cycle.
1902970	premeiotic DNA replication DNA duplex unwinding	P	Any DNA duplex unwinding involved in meiotic cell cycle DNA replication.
1902971	mitotic DNA replication DNA duplex unwinding	P	Any DNA duplex unwinding involved in mitotic cell cycle DNA replication.
1902972	premeiotic DNA replication DNA ligation	P	Any DNA ligation involved in meiotic cell cycle DNA replication.
1902973	mitotic DNA replication DNA ligation	P	Any DNA ligation involved in mitotic cell cycle DNA replication.
1902974	meiotic DNA replication initiation	P	Any DNA replication initiation involved in meiotic cell cycle DNA replication.
1902975	mitotic DNA replication initiation	P	Any DNA replication initiation involved in mitotic cell cycle DNA replication.
1902976	premeiotic DNA replication preinitiation complex assembly	P	Any DNA replication preinitiation complex assembly that is involved in meiotic cell cycle.
1902977	mitotic DNA replication preinitiation complex assembly	P	Any DNA replication preinitiation complex assembly that is involved in mitotic cell cycle.
1902978	premeiotic DNA replication termination	P	Any DNA replication termination involved in meiotic cell cycle DNA replication.
1902979	mitotic DNA replication termination	P	Any DNA replication termination involved in mitotic cell cycle DNA replication.
1902980	synthesis of RNA primer involved in premeiotic DNA replication	P	Any synthesis of RNA primer involved in meiotic cell cycle DNA replication.
1902981	synthesis of RNA primer involved in mitotic DNA replication	P	Any synthesis of RNA primer involved in mitotic cell cycle DNA replication.
1902982	DNA strand elongation involved in premeiotic DNA replication	P	Any DNA strand elongation involved in meiotic cell cycle DNA replication.
1902983	DNA strand elongation involved in mitotic DNA replication	P	Any DNA strand elongation involved in mitotic cell cycle DNA replication.
1902984	pre-replicative complex assembly involved in premeiotic DNA replication	P	Any pre-replicative complex assembly involved in meiotic cell cycle DNA replication.
1902985	mitotic pre-replicative complex assembly	P	Any pre-replicative complex assembly involved in mitotic cell cycle DNA replication.
1902986	regulation of lysine biosynthetic process via aminoadipic acid	P	Any process that modulates the frequency, rate or extent of lysine biosynthetic process via aminoadipic acid.
1902987	negative regulation of lysine biosynthetic process via aminoadipic acid	P	Any process that stops, prevents or reduces the frequency, rate or extent of lysine biosynthetic process via aminoadipic acid.
1902988	neurofibrillary tangle assembly	P	The aggregation, arrangement and bonding together of a set of components to form a neurofibrillary tangle.
1902989	meiotic telomere maintenance via semi-conservative replication	P	Any telomere maintenance via semi-conservative replication that is involved in meiotic cell cycle.
1902990	mitotic telomere maintenance via semi-conservative replication	P	Any telomere maintenance via semi-conservative replication that is involved in mitotic cell cycle.
1902991	regulation of amyloid precursor protein catabolic process	P	Any process that modulates the frequency, rate or extent of amyloid precursor protein catabolic process.
1902992	negative regulation of amyloid precursor protein catabolic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of amyloid precursor protein catabolic process.
1902993	positive regulation of amyloid precursor protein catabolic process	P	Any process that activates or increases the frequency, rate or extent of amyloid precursor protein catabolic process.
1902994	regulation of phospholipid efflux	P	Any process that modulates the frequency, rate or extent of phospholipid efflux.
1902995	positive regulation of phospholipid efflux	P	Any process that activates or increases the frequency, rate or extent of phospholipid efflux.
1902996	regulation of neurofibrillary tangle assembly	P	Any process that modulates the frequency, rate or extent of neurofibrillary tangle assembly.
1902997	negative regulation of neurofibrillary tangle assembly	P	Any process that stops, prevents or reduces the frequency, rate or extent of neurofibrillary tangle assembly.
1902998	positive regulation of neurofibrillary tangle assembly	P	Any process that activates or increases the frequency, rate or extent of neurofibrillary tangle assembly.
1902999	negative regulation of phospholipid efflux	P	Any process that stops, prevents or reduces the frequency, rate or extent of phospholipid efflux.
1903000	regulation of lipid transport across blood brain barrier	P	Any process that modulates the frequency, rate or extent of lipid transport across blood brain barrier.
1903001	negative regulation of lipid transport across blood brain barrier	P	Any process that stops, prevents or reduces the frequency, rate or extent of lipid transport across blood brain barrier.
1903002	positive regulation of lipid transport across blood brain barrier	P	Any process that activates or increases the frequency, rate or extent of lipid transport across blood brain barrier.
1903003	positive regulation of protein deubiquitination	P	Any process that activates or increases the frequency, rate or extent of protein deubiquitination.
1903004	regulation of protein K63-linked deubiquitination	P	Any process that modulates the frequency, rate or extent of protein K63-linked deubiquitination.
1903005	negative regulation of protein K63-linked deubiquitination	P	Any process that stops, prevents or reduces the frequency, rate or extent of protein K63-linked deubiquitination.
1903006	positive regulation of protein K63-linked deubiquitination	P	Any process that activates or increases the frequency, rate or extent of protein K63-linked deubiquitination.
1903007	positive regulation of Lys63-specific deubiquitinase activity	P	Any process that activates or increases the frequency, rate or extent of Lys63-specific deubiquitinase activity.
1903008	organelle disassembly	P	The disaggregation of an organelle into its constituent components.
1903009	proteasome complex disassembly	P	The disaggregation of a proteasome complex into its constituent components.
1903010	regulation of bone development	P	Any process that modulates the frequency, rate or extent of bone development.
1903011	negative regulation of bone development	P	Any process that stops, prevents or reduces the frequency, rate or extent of bone development.
1903012	positive regulation of bone development	P	Any process that activates or increases the frequency, rate or extent of bone development.
1903013	response to 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one stimulus.
1903014	cellular response to 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)hexan-1-one stimulus.
1903015	regulation of exo-alpha-sialidase activity	P	Any process that modulates the frequency, rate or extent of exo-alpha-sialidase activity.
1903016	negative regulation of exo-alpha-sialidase activity	P	Any process that stops, prevents or reduces the frequency, rate or extent of exo-alpha-sialidase activity.
1903017	positive regulation of exo-alpha-sialidase activity	P	Any process that activates or increases the frequency, rate or extent of exo-alpha-sialidase activity.
1903018	regulation of glycoprotein metabolic process	P	Any process that modulates the frequency, rate or extent of glycoprotein metabolic process.
1903019	negative regulation of glycoprotein metabolic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of glycoprotein metabolic process.
1903020	positive regulation of glycoprotein metabolic process	P	Any process that activates or increases the frequency, rate or extent of glycoprotein metabolic process.
1903021	regulation of phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands	P	Any process that modulates the frequency, rate or extent of phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands.
1903022	positive regulation of phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands	P	Any process that activates or increases the frequency, rate or extent of phosphodiesterase activity, acting on 3'-phosphoglycolate-terminated DNA strands.
1903023	regulation of ascospore-type prospore membrane assembly	P	Any process that modulates the frequency, rate or extent of ascospore-type prospore membrane assembly.
1903024	positive regulation of ascospore-type prospore membrane assembly	P	Any process that activates or increases the frequency, rate or extent of ascospore-type prospore membrane assembly.
1903025	regulation of RNA polymerase II regulatory region sequence-specific DNA binding	P	Any process that modulates the frequency, rate or extent of RNA polymerase II regulatory region sequence-specific DNA binding.
1903026	negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding	P	Any process that stops, prevents or reduces the frequency, rate or extent of RNA polymerase II regulatory region sequence-specific DNA binding.
1903027	regulation of opsonization	P	Any process that modulates the frequency, rate or extent of opsonization.
1903028	positive regulation of opsonization	P	Any process that activates or increases the frequency, rate or extent of opsonization.
1903031	regulation of microtubule plus-end binding	P	Any process that modulates the frequency, rate or extent of microtubule plus-end binding.
1903032	negative regulation of microtubule plus-end binding	P	Any process that stops, prevents or reduces the frequency, rate or extent of microtubule plus-end binding.
1903033	positive regulation of microtubule plus-end binding	P	Any process that activates or increases the frequency, rate or extent of microtubule plus-end binding.
1903034	regulation of response to wounding	P	Any process that modulates the frequency, rate or extent of response to wounding.
1903035	negative regulation of response to wounding	P	Any process that stops, prevents or reduces the frequency, rate or extent of response to wounding.
1903036	positive regulation of response to wounding	P	Any process that activates or increases the frequency, rate or extent of response to wounding.
1903037	regulation of leukocyte cell-cell adhesion	P	Any process that modulates the frequency, rate or extent of leukocyte cell-cell adhesion.
1903038	negative regulation of leukocyte cell-cell adhesion	P	Any process that stops, prevents or reduces the frequency, rate or extent of leukocyte cell-cell adhesion.
1903039	positive regulation of leukocyte cell-cell adhesion	P	Any process that activates or increases the frequency, rate or extent of leukocyte cell-cell adhesion.
1903040	exon-exon junction complex assembly	P	The aggregation, arrangement and bonding together of a set of components to form an exon-exon junction complex.
1903041	regulation of chondrocyte hypertrophy	P	Any process that modulates the frequency, rate or extent of chondrocyte hypertrophy.
1903042	negative regulation of chondrocyte hypertrophy	P	Any process that stops, prevents or reduces the frequency, rate or extent of chondrocyte hypertrophy.
1903043	positive regulation of chondrocyte hypertrophy	P	Any process that activates or increases the frequency, rate or extent of chondrocyte hypertrophy.
1903044	protein localization to membrane raft	P	A process in which a protein is transported to, or maintained in, a location within a membrane raft.
1903045	neural crest cell migration involved in sympathetic nervous system development	P	Any neural crest cell migration that is involved in sympathetic nervous system development.
1903046	meiotic cell cycle process	P	A process that is part of the meiotic cell cycle.
1903047	mitotic cell cycle process	P	A process that is part of the mitotic cell cycle.
1903048	regulation of acetylcholine-gated cation channel activity	P	Any process that modulates the frequency, rate or extent of acetylcholine-gated cation channel activity.
1903049	negative regulation of acetylcholine-gated cation channel activity	P	Any process that stops, prevents or reduces the frequency, rate or extent of acetylcholine-gated cation channel activity.
1903050	regulation of proteolysis involved in cellular protein catabolic process	P	Any process that modulates the frequency, rate or extent of proteolysis involved in cellular protein catabolic process.
1903051	negative regulation of proteolysis involved in cellular protein catabolic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of proteolysis involved in cellular protein catabolic process.
1903052	positive regulation of proteolysis involved in cellular protein catabolic process	P	Any process that activates or increases the frequency, rate or extent of proteolysis involved in cellular protein catabolic process.
1903053	regulation of extracellular matrix organization	P	Any process that modulates the frequency, rate or extent of extracellular matrix organization.
1903054	negative regulation of extracellular matrix organization	P	Any process that stops, prevents or reduces the frequency, rate or extent of extracellular matrix organization.
1903055	positive regulation of extracellular matrix organization	P	Any process that activates or increases the frequency, rate or extent of extracellular matrix organization.
1903056	regulation of melanosome organization	P	Any process that modulates the frequency, rate or extent of melanosome organization.
1903057	negative regulation of melanosome organization	P	Any process that stops, prevents or reduces the frequency, rate or extent of melanosome organization.
1903058	positive regulation of melanosome organization	P	Any process that activates or increases the frequency, rate or extent of melanosome organization.
1903059	regulation of protein lipidation	P	Any process that modulates the frequency, rate or extent of protein lipidation.
1903060	negative regulation of protein lipidation	P	Any process that stops, prevents or reduces the frequency, rate or extent of protein lipidation.
1903061	positive regulation of protein lipidation	P	Any process that activates or increases the frequency, rate or extent of protein lipidation.
1903062	regulation of reverse cholesterol transport	P	Any process that modulates the frequency, rate or extent of reverse cholesterol transport.
1903063	negative regulation of reverse cholesterol transport	P	Any process that stops, prevents or reduces the frequency, rate or extent of reverse cholesterol transport.
1903064	positive regulation of reverse cholesterol transport	P	Any process that activates or increases the frequency, rate or extent of reverse cholesterol transport.
1903066	regulation of protein localization to cell tip	P	Any process that modulates the frequency, rate or extent of protein localization to cell tip.
1903067	negative regulation of protein localization to cell tip	P	Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cell tip.
1903068	positive regulation of protein localization to cell tip	P	Any process that activates or increases the frequency, rate or extent of protein localization to cell tip.
1903069	regulation of ER-associated ubiquitin-dependent protein catabolic process	P	Any process that modulates the frequency, rate or extent of ER-associated ubiquitin-dependent protein catabolic process.
1903070	negative regulation of ER-associated ubiquitin-dependent protein catabolic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of ER-associated ubiquitin-dependent protein catabolic process.
1903071	positive regulation of ER-associated ubiquitin-dependent protein catabolic process	P	Any process that activates or increases the frequency, rate or extent of ER-associated ubiquitin-dependent protein catabolic process.
1903072	regulation of death-inducing signaling complex assembly	P	Any process that modulates the frequency, rate or extent of death-inducing signaling complex assembly.
1903073	negative regulation of death-inducing signaling complex assembly	P	Any process that stops, prevents or reduces the frequency, rate or extent of death-inducing signaling complex assembly.
1903074	TRAIL death-inducing signaling complex assembly	P	The aggregation, arrangement and bonding together of a set of components to form a TRAIL death-inducing signaling complex.
1903075	pyridoxine import into cell	P	The directed movement of pyridoxine from outside of a cell into the intracellular region of a cell.
1903076	regulation of protein localization to plasma membrane	P	Any process that modulates the frequency, rate or extent of protein localization to plasma membrane.
1903077	negative regulation of protein localization to plasma membrane	P	Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to plasma membrane.
1903078	positive regulation of protein localization to plasma membrane	P	Any process that activates or increases the frequency, rate or extent of protein localization to plasma membrane.
1903080	regulation of C-C chemokine receptor CCR7 signaling pathway	P	Any process that modulates the frequency, rate or extent of C-C chemokine receptor CCR7 signaling pathway.
1903081	negative regulation of C-C chemokine receptor CCR7 signaling pathway	P	Any process that stops, prevents or reduces the frequency, rate or extent of C-C chemokine receptor CCR7 signaling pathway.
1903082	positive regulation of C-C chemokine receptor CCR7 signaling pathway	P	Any process that activates or increases the frequency, rate or extent of C-C chemokine receptor CCR7 signaling pathway.
1903083	protein localization to condensed chromosome	P	A process in which a protein is transported to, or maintained in, a location within a condensed chromosome.
1903084	protein localization to condensed nuclear chromosome	P	A process in which a protein is transported to, or maintained in, a location within a condensed nuclear chromosome.
1903085	regulation of sinapate ester biosynthetic process	P	Any process that modulates the frequency, rate or extent of sinapate ester biosynthesis.
1903086	negative regulation of sinapate ester biosynthetic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of sinapate ester biosynthesis.
1903087	mitotic spindle pole body duplication	P	Any spindle pole body duplication that is involved in the mitotic cell cycle.
1903088	5-amino-1-ribofuranosylimidazole-4-carboxamide transmembrane transport	P	The directed movement of 5-amino-1-ribofuranosylimidazole-4-carboxamide across a membrane.
1903089	5-amino-1-ribofuranosylimidazole-4-carboxamide transporter activity	F	Enables the directed movement of 5-amino-1-ribofuranosylimidazole-4-carboxamide into, out of or within a cell, or between cells.
1903090	pyridoxal transmembrane transport	P	The directed movement of pyridoxal across a membrane.
1903091	pyridoxamine transmembrane transport	P	The directed movement of pyridoxamine across a membrane.
1903092	pyridoxine transmembrane transport	P	The directed movement of pyridoxine across a membrane.
1903093	regulation of protein K48-linked deubiquitination	P	Any process that modulates the frequency, rate or extent of protein K48-linked deubiquitination.
1903094	negative regulation of protein K48-linked deubiquitination	P	Any process that stops, prevents or reduces the frequency, rate or extent of protein K48-linked deubiquitination.
1903095	ribonuclease III complex	C	A protein complex which is capable of ribonuclease III activity.
1903096	protein localization to meiotic spindle midzone	P	A process in which a protein is transported to, or maintained in, a location within a meiotic spindle midzone.
1903097	regulation of CENP-A containing nucleosome assembly	P	Any process that modulates the rate, frequency or extent of the formation of nucleosomes containing the histone H3 variant CENP-A to form centromeric chromatin. This specialised chromatin occurs at centromeric region in point centromeres, and the central core in modular centromeres.
1903098	negative regulation of CENP-A containing nucleosome assembly	P	Any process that stops, prevents or reduces the frequency, rate or extent of the formation of nucleosomes containing the histone H3 variant CENP-A to form centromeric chromatin. This specialised chromatin occurs at centromeric region in point centromeres, and the central core in modular centromeres.
1903099	positive regulation of CENP-A containing nucleosome assembly	P	Any process that activates or increases the frequency, rate or extent of the formation of nucleosomes containing the histone H3 variant CENP-A to form centromeric chromatin. This specialised chromatin occurs at centromeric region in point centromeres, and the central core in modular centromeres.
1903100	1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate metabolic process	P	The chemical reactions and pathways involving 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate.
1903101	1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate.
1903102	1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of 1-phosphatidyl-1D-myo-inositol 3,5-bisphosphate.
1903103	potassium:proton antiporter complex	C	A protein complex which is capable of potassium:proton antiporter activity.
1903104	regulation of insulin receptor signaling pathway involved in determination of adult lifespan	P	Any process that modulates the frequency, rate or extent of insulin receptor signaling pathway involved in determination of adult lifespan.
1903105	negative regulation of insulin receptor signaling pathway involved in determination of adult lifespan	P	Any process that stops, prevents or reduces the frequency, rate or extent of insulin receptor signaling pathway involved in determination of adult lifespan.
1903106	positive regulation of insulin receptor signaling pathway involved in determination of adult lifespan	P	Any process that activates or increases the frequency, rate or extent of insulin receptor signaling pathway involved in determination of adult lifespan.
1903107	insulin receptor signaling pathway involved in dauer larval development	P	Any insulin receptor signaling pathway that is involved in dauer larval development.
1903108	regulation of transcription from mitochondrial promoter	P	Any process that modulates the frequency, rate or extent of transcription from mitochondrial promoter.
1903109	positive regulation of transcription from mitochondrial promoter	P	Any process that activates or increases the frequency, rate or extent of transcription from mitochondrial promoter.
1903110	regulation of single-strand break repair via homologous recombination	P	Any process that modulates the frequency, rate or extent of single-strand break repair via homologous recombination.
1903111	negative regulation of single-strand break repair via homologous recombination	P	Any process that stops, prevents or reduces the frequency, rate or extent of single-strand break repair via homologous recombination.
1903112	positive regulation of single-strand break repair via homologous recombination	P	Any process that activates or increases the frequency, rate or extent of single-strand break repair via homologous recombination.
1903113	copper ion transmembrane transporter complex	C	A protein complex which is capable of copper ion transmembrane transporter activity.
1903114	silver ion transmembrane transporter complex	C	A protein complex which is capable of silver ion transmembrane transporter activity.
1903115	regulation of actin filament-based movement	P	Any process that modulates the frequency, rate or extent of actin filament-based movement.
1903116	positive regulation of actin filament-based movement	P	Any process that activates or increases the frequency, rate or extent of actin filament-based movement.
1903117	regulation of actin filament organization involved in cytokinetic actomyosin contractile ring assembly	P	Any process that modulates the frequency, rate or extent of actin filament organization involved in cytokinetic actomyosin contractile ring assembly.
1903118	urate homeostasis	P	Any process involved in the maintenance of an internal steady state of urate within an organism or cell.
1903119	protein localization to actin cytoskeleton	P	A process in which a protein is transported to, or maintained in, the location of an actin cytoskeleton.
1903120	protein localization to actin filament bundle	P	A process in which a protein is transported to, or maintained in, the location of an actin filament bundle.
1903121	regulation of TRAIL-activated apoptotic signaling pathway	P	Any process that modulates the frequency, rate or extent of TRAIL-activated apoptotic signaling pathway.
1903122	negative regulation of TRAIL-activated apoptotic signaling pathway	P	Any process that stops, prevents or reduces the frequency, rate or extent of TRAIL-activated apoptotic signaling pathway.
1903123	regulation of thioredoxin peroxidase activity	P	Any process that modulates the frequency, rate or extent of thioredoxin peroxidase activity.
1903124	negative regulation of thioredoxin peroxidase activity	P	Any process that stops, prevents or reduces the frequency, rate or extent of thioredoxin peroxidase activity.
1903125	negative regulation of thioredoxin peroxidase activity by peptidyl-threonine phosphorylation	P	A peptidyl-threonine phosphorylation that results in negative regulation of thioredoxin peroxidase activity.
1903126	negative regulation of centriole-centriole cohesion	P	Any process that stops, prevents or reduces the frequency, rate or extent of centriole-centriole cohesion.
1903127	positive regulation of centriole-centriole cohesion	P	Any process that activates or increases the frequency, rate or extent of centriole-centriole cohesion.
1903128	regulation of leucine import into cell	P	Any process that modulates the frequency, rate or extent of leucine import into cell.
1903129	negative regulation of leucine import into cell	P	Any process that stops, prevents or reduces the frequency, rate or extent of leucine import into cell.
1903130	positive regulation of leucine import into cell	P	Any process that activates or increases the frequency, rate or extent of leucine import into cell.
1903131	mononuclear cell differentiation	P	The process in which a relatively unspecialized cell acquires the specialized features of a mononuclear cell.
1903132	regulation of tube lumen cavitation	P	Any process that modulates the frequency, rate or extent of tube lumen cavitation.
1903133	negative regulation of tube lumen cavitation	P	Any process that stops, prevents or reduces the frequency, rate or extent of tube lumen cavitation.
1903134	trehalose catabolic process involved in cellular response to stress	P	Any trehalose catabolic process that is involved in cellular response to stress.
1903135	cupric ion binding	F	Interacting selectively and non-covalently with cupric ion, copper(2+).
1903136	cuprous ion binding	F	Interacting selectively and non-covalently with cuprous ion, copper(1+).
1903137	regulation of MAPK cascade involved in cell wall organization or biogenesis	P	Any process that modulates the frequency, rate or extent of MAPK cascade involved in cell wall organization or biogenesis.
1903138	negative regulation of MAPK cascade involved in cell wall organization or biogenesis	P	Any process that stops, prevents or reduces the frequency, rate or extent of MAPK cascade involved in cell wall organization or biogenesis.
1903139	positive regulation of MAPK cascade involved in cell wall organization or biogenesis	P	Any process that activates or increases the frequency, rate or extent of MAPK cascade involved in cell wall organization or biogenesis.
1903140	regulation of establishment of endothelial barrier	P	Any process that modulates the frequency, rate or extent of establishment of endothelial barrier.
1903141	negative regulation of establishment of endothelial barrier	P	Any process that stops, prevents or reduces the frequency, rate or extent of establishment of endothelial barrier.
1903142	positive regulation of establishment of endothelial barrier	P	Any process that activates or increases the frequency, rate or extent of establishment of endothelial barrier.
1903143	adrenomedullin receptor complex	C	A transmembrane, G-protein-coupled signalling receptor complex which is capable of adrenomedullin receptor activity.
1903144	actomyosin contractile ring actin filament	C	Any actin filament that is part of a actomyosin contractile ring.
1903145	actin filament of cell cortex of cell tip	C	Any actin filament that is part of a cell cortex of cell tip.
1903146	regulation of mitophagy	P	Any process that modulates the frequency, rate or extent of mitochondrion degradation (mitophagy).
1903147	negative regulation of mitophagy	P	Any process that stops, prevents or reduces the frequency, rate or extent of mitochondrion degradation (mitophagy).
1903165	response to polycyclic arene	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a polycyclic arene stimulus.
1903166	cellular response to polycyclic arene	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a polycyclic arene stimulus.
1903167	regulation of pyrroline-5-carboxylate reductase activity	P	Any process that modulates the frequency, rate or extent of pyrroline-5-carboxylate reductase activity.
1903168	positive regulation of pyrroline-5-carboxylate reductase activity	P	Any process that activates or increases the frequency, rate or extent of pyrroline-5-carboxylate reductase activity.
1903169	regulation of calcium ion transmembrane transport	P	Any process that modulates the frequency, rate or extent of calcium ion transmembrane transport.
1903170	negative regulation of calcium ion transmembrane transport	P	Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion transmembrane transport.
1903171	carbon dioxide homeostasis	P	Any process involved in the maintenance of an internal steady state of carbon dioxide within an organism or cell.
1903172	cellular carbon dioxide homeostasis	P	Any biological process involved in the maintenance of an internal steady state of carbon dioxide at the level of the cell.
1903173	fatty alcohol metabolic process	P	The chemical reactions and pathways involving fatty alcohol.
1903174	fatty alcohol catabolic process	P	The chemical reactions and pathways resulting in the breakdown of fatty alcohol.
1903175	fatty alcohol biosynthetic process	P	The chemical reactions and pathways resulting in the formation of fatty alcohol.
1903176	regulation of tyrosine 3-monooxygenase activity	P	Any process that modulates the frequency, rate or extent of tyrosine 3-monooxygenase activity.
1903177	negative regulation of tyrosine 3-monooxygenase activity	P	Any process that stops, prevents or reduces the frequency, rate or extent of tyrosine 3-monooxygenase activity.
1903178	positive regulation of tyrosine 3-monooxygenase activity	P	Any process that activates or increases the frequency, rate or extent of tyrosine 3-monooxygenase activity.
1903179	regulation of dopamine biosynthetic process	P	Any process that modulates the frequency, rate or extent of dopamine biosynthetic process.
1903180	negative regulation of dopamine biosynthetic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of dopamine biosynthetic process.
1903181	positive regulation of dopamine biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of dopamine biosynthetic process.
1903182	regulation of SUMO transferase activity	P	Any process that modulates the frequency, rate or extent of SUMO ligase activity.
1903183	negative regulation of SUMO transferase activity	P	Any process that stops, prevents or reduces the frequency, rate or extent of SUMO ligase activity.
1903184	L-dopa metabolic process	P	The chemical reactions and pathways involving L-dopa.
1903185	L-dopa biosynthetic process	P	The chemical reactions and pathways resulting in the formation of L-dopa.
1903186	regulation of vitellogenesis	P	Any process that modulates the frequency, rate or extent of vitellogenesis.
1903187	negative regulation of vitellogenesis	P	Any process that stops, prevents or reduces the frequency, rate or extent of vitellogenesis.
1903188	positive regulation of vitellogenesis	P	Any process that activates or increases the frequency, rate or extent of vitellogenesis.
1903189	glyoxal metabolic process	P	The chemical reactions and pathways involving glyoxal.
1903190	glyoxal catabolic process	P	The chemical reactions and pathways resulting in the breakdown of glyoxal.
1903191	glyoxal biosynthetic process	P	The chemical reactions and pathways resulting in the formation of glyoxal.
1903192	sesquarterpene metabolic process	P	The chemical reactions and pathways involving sesquarterpene.
1903193	sesquarterpene biosynthetic process	P	The chemical reactions and pathways resulting in the formation of sesquarterpene.
1903195	regulation of L-dopa biosynthetic process	P	Any process that modulates the frequency, rate or extent of L-dopa biosynthetic process.
1903196	negative regulation of L-dopa biosynthetic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of L-dopa biosynthetic process.
1903197	positive regulation of L-dopa biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of L-dopa biosynthetic process.
1903198	regulation of L-dopa decarboxylase activity	P	Any process that modulates the frequency, rate or extent of L-dopa decarboxylase activity.
1903199	negative regulation of L-dopa decarboxylase activity	P	Any process that stops, prevents or reduces the frequency, rate or extent of L-dopa decarboxylase activity.
1903200	positive regulation of L-dopa decarboxylase activity	P	Any process that activates or increases the frequency, rate or extent of L-dopa decarboxylase activity.
1903201	regulation of oxidative stress-induced cell death	P	Any process that modulates the frequency, rate or extent of oxidative stress-induced cell death.
1903202	negative regulation of oxidative stress-induced cell death	P	Any process that stops, prevents or reduces the frequency, rate or extent of oxidative stress-induced cell death.
1903203	regulation of oxidative stress-induced neuron death	P	Any process that modulates the frequency, rate or extent of oxidative stress-induced neuron death.
1903204	negative regulation of oxidative stress-induced neuron death	P	Any process that stops, prevents or reduces the frequency, rate or extent of oxidative stress-induced neuron death.
1903205	regulation of hydrogen peroxide-induced cell death	P	Any process that modulates the frequency, rate or extent of hydrogen peroxide-induced cell death.
1903206	negative regulation of hydrogen peroxide-induced cell death	P	Any process that stops, prevents or reduces the frequency, rate or extent of hydrogen peroxide-induced cell death.
1903207	regulation of hydrogen peroxide-induced neuron death	P	Any process that modulates the frequency, rate or extent of hydrogen peroxide-induced neuron death.
1903208	negative regulation of hydrogen peroxide-induced neuron death	P	Any process that stops, prevents or reduces the frequency, rate or extent of hydrogen peroxide-induced neuron death.
1903209	positive regulation of oxidative stress-induced cell death	P	Any process that activates or increases the frequency, rate or extent of oxidative stress-induced cell death.
1903210	glomerular visceral epithelial cell apoptotic process	P	Any apoptotic process in a glomerular visceral epithelial cell.
1903211	mitotic recombination involved in replication fork processing	P	Any mitotic recombination that is involved in replication fork processing.
1903212	protein localization to mating-type region heterochromatin	P	A process in which a protein is transported to, or maintained in, a location within a mating-type region heterochromatin.
1903213	protein localization to subtelomeric heterochromatin	P	A process in which a protein is transported to, or maintained in, a location within a subtelomeric heterochromatin.
1903214	regulation of protein targeting to mitochondrion	P	Any process that modulates the frequency, rate or extent of protein targeting to mitochondrion.
1903215	negative regulation of protein targeting to mitochondrion	P	Any process that stops, prevents or reduces the frequency, rate or extent of protein targeting to mitochondrion.
1903216	regulation of protein processing involved in protein targeting to mitochondrion	P	Any process that modulates the frequency, rate or extent of protein processing involved in protein targeting to mitochondrion.
1903217	negative regulation of protein processing involved in protein targeting to mitochondrion	P	Any process that stops, prevents or reduces the frequency, rate or extent of protein processing involved in protein targeting to mitochondrion.
1903218	regulation of malate dehydrogenase (decarboxylating) (NADP+) activity	P	Any process that modulates the frequency, rate or extent of malate dehydrogenase (decarboxylating) (NADP+) activity.
1903219	negative regulation of malate dehydrogenase (decarboxylating) (NADP+) activity	P	Any process that stops, prevents or reduces the frequency, rate or extent of malate dehydrogenase (decarboxylating) (NADP+) activity.
1903220	positive regulation of malate dehydrogenase (decarboxylating) (NADP+) activity	P	Any process that activates or increases the frequency, rate or extent of malate dehydrogenase (decarboxylating) (NADP+) activity.
1903221	regulation of mitotic recombination involved in replication fork processing	P	Any process that modulates the frequency, rate or extent of mitotic recombination involved in replication fork processing. Regulation of mitotic recombination contributes to replication fork processing by preventing recombination between inappropriate homologous sequences.
1903222	quinolinic acid transmembrane transport	P	The directed movement of quinolinic acid across a membrane.
1903223	positive regulation of oxidative stress-induced neuron death	P	Any process that activates or increases the frequency, rate or extent of oxidative stress-induced neuron death.
1903224	regulation of endodermal cell differentiation	P	Any process that modulates the frequency, rate or extent of endodermal cell differentiation.
1903225	negative regulation of endodermal cell differentiation	P	Any process that stops, prevents or reduces the frequency, rate or extent of endodermal cell differentiation.
1903226	positive regulation of endodermal cell differentiation	P	Any process that activates or increases the frequency, rate or extent of endodermal cell differentiation.
1903227	xanthosine metabolic process	P	The chemical reactions and pathways involving xanthosine.
1903228	xanthosine catabolic process	P	The chemical reactions and pathways resulting in the breakdown of xanthosine.
1903229	xanthosine biosynthetic process	P	The chemical reactions and pathways resulting in the formation of xanthosine.
1903231	mRNA binding involved in posttranscriptional gene silencing	F	Any mRNA binding that is involved in posttranscriptional gene silencing.
1903232	melanosome assembly	P	The aggregation, arrangement and bonding together of a set of components to form a melanosome, a tissue-specific, membrane-bounded cytoplasmic organelle within which melanin pigments are synthesized and stored.
1903233	regulation of calcium ion-dependent exocytosis of neurotransmitter	P	Any process that modulates the frequency, rate or extent of calcium ion-dependent exocytosis of neurotransmitter.
1903234	negative regulation of calcium ion-dependent exocytosis of neurotransmitter	P	Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion-dependent exocytosis of neurotransmitter.
1903235	positive regulation of calcium ion-dependent exocytosis of neurotransmitter	P	Any process that activates or increases the frequency, rate or extent of calcium ion-dependent exocytosis of neurotransmitter.
1903236	regulation of leukocyte tethering or rolling	P	Any process that modulates the frequency, rate or extent of leukocyte tethering or rolling.
1903237	negative regulation of leukocyte tethering or rolling	P	Any process that stops, prevents or reduces the frequency, rate or extent of leukocyte tethering or rolling.
1903238	positive regulation of leukocyte tethering or rolling	P	Any process that activates or increases the frequency, rate or extent of leukocyte tethering or rolling.
1903241	U2-type prespliceosome assembly	P	The aggregation, arrangement and bonding together of a set of components to form an U2-type prespliceosome.
1903242	regulation of cardiac muscle hypertrophy in response to stress	P	Any process that modulates the frequency, rate or extent of cardiac muscle hypertrophy in response to stress.
1903243	negative regulation of cardiac muscle hypertrophy in response to stress	P	Any process that stops, prevents or reduces the frequency, rate or extent of cardiac muscle hypertrophy in response to stress.
1903244	positive regulation of cardiac muscle hypertrophy in response to stress	P	Any process that activates or increases the frequency, rate or extent of cardiac muscle hypertrophy in response to stress.
1903245	regulation of adrenergic receptor signaling pathway involved in positive regulation of heart rate	P	Any process that modulates the frequency, rate or extent of adrenergic receptor signaling pathway involved in positive regulation of heart rate.
1903246	negative regulation of adrenergic receptor signaling pathway involved in positive regulation of heart rate	P	Any process that stops, prevents or reduces the frequency, rate or extent of adrenergic receptor signaling pathway involved in positive regulation of heart rate.
1903247	positive regulation of adrenergic receptor signaling pathway involved in positive regulation of heart rate	P	Any process that activates or increases the frequency, rate or extent of adrenergic receptor signaling pathway involved in positive regulation of heart rate.
1903248	regulation of citrulline biosynthetic process	P	Any process that modulates the frequency, rate or extent of citrulline biosynthetic process.
1903249	negative regulation of citrulline biosynthetic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of citrulline biosynthetic process.
1903250	positive regulation of citrulline biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of citrulline biosynthetic process.
1903251	multi-ciliated epithelial cell differentiation	P	The process in which a relatively unspecialized cell acquires the specialized features of a multi-ciliated epithelial cell.
1903252	hercynylcysteine sulfoxide metabolic process	P	The chemical reactions and pathways involving hercynylcysteine sulfoxide.
1903253	hercynylcysteine sulfoxide biosynthetic process	P	The chemical reactions and pathways resulting in the formation of hercynylcysteine sulfoxide.
1903254	hercynylselenocysteine metabolic process	P	The chemical reactions and pathways involving hercynylselenocysteine.
1903255	hercynylselenocysteine biosynthetic process	P	The chemical reactions and pathways resulting in the formation of hercynylselenocysteine.
1903256	selenoneine metabolic process	P	The chemical reactions and pathways involving selenoneine.
1903257	selenoneine biosynthetic process	P	The chemical reactions and pathways resulting in the formation of selenoneine.
1903258	sorbose import into cell	P	The directed movement of sorbose into a cell.
1903259	exon-exon junction complex disassembly	P	The disaggregation of an exon-exon junction complex into its constituent components.
1903260	protein localization to mating projection tip	P	A process in which a protein is transported to, or maintained in, a location within a mating projection tip.
1903261	regulation of serine phosphorylation of STAT3 protein	P	Any process that modulates the frequency, rate or extent of serine phosphorylation of STAT3 protein.
1903262	negative regulation of serine phosphorylation of STAT3 protein	P	Any process that stops, prevents or reduces the frequency, rate or extent of serine phosphorylation of STAT3 protein.
1903263	positive regulation of serine phosphorylation of STAT3 protein	P	Any process that activates or increases the frequency, rate or extent of serine phosphorylation of STAT3 protein.
1903264	nitrate reductase activity involved in anaerobic electron transport chain	F	Any nitrate reductase activity that is involved in anaerobic electron transport chain.
1903265	positive regulation of tumor necrosis factor-mediated signaling pathway	P	Any process that activates or increases the frequency, rate or extent of tumor necrosis factor-mediated signaling pathway.
1903266	regulation of ornithine catabolic process	P	Any process that modulates the frequency, rate or extent of ornithine catabolic process.
1903267	negative regulation of ornithine catabolic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of ornithine catabolic process.
1903268	positive regulation of ornithine catabolic process	P	Any process that activates or increases the frequency, rate or extent of ornithine catabolic process.
1903269	ornithine carbamoyltransferase inhibitor complex	C	A protein complex which is capable of ornithine carbamoyltransferase inhibitor activity.
1903270	regulation of cytoplasmic translational elongation through polyproline stretches	P	Any process that modulates the frequency, rate or extent of cytoplasmic translational elongation through polyproline stretches.
1903271	negative regulation of cytoplasmic translational elongation through polyproline stretches	P	Any process that stops, prevents or reduces the frequency, rate or extent of cytoplasmic translational elongation through polyproline stretches.
1903272	positive regulation of cytoplasmic translational elongation through polyproline stretches	P	Any process that activates or increases the frequency, rate or extent of cytoplasmic translational elongation through polyproline stretches.
1903273	regulation of sodium ion export	P	Any process that modulates the frequency, rate or extent of sodium ion export.
1903274	negative regulation of sodium ion export	P	Any process that stops, prevents or reduces the frequency, rate or extent of sodium ion export.
1903275	positive regulation of sodium ion export	P	Any process that activates or increases the frequency, rate or extent of sodium ion export.
1903276	regulation of sodium ion export from cell	P	Any process that modulates the frequency, rate or extent of sodium ion export from cell.
1903277	negative regulation of sodium ion export from cell	P	Any process that stops, prevents or reduces the frequency, rate or extent of sodium ion export from cell.
1903278	positive regulation of sodium ion export from cell	P	Any process that activates or increases the frequency, rate or extent of sodium ion export from cell.
1903279	regulation of calcium:sodium antiporter activity	P	Any process that modulates the frequency, rate or extent of calcium:sodium antiporter activity.
1903280	negative regulation of calcium:sodium antiporter activity	P	Any process that stops, prevents or reduces the frequency, rate or extent of calcium:sodium antiporter activity.
1903281	positive regulation of calcium:sodium antiporter activity	P	Any process that activates or increases the frequency, rate or extent of calcium:sodium antiporter activity.
1903282	regulation of glutathione peroxidase activity	P	Any process that modulates the frequency, rate or extent of glutathione peroxidase activity.
1903283	negative regulation of glutathione peroxidase activity	P	Any process that stops, prevents or reduces the frequency, rate or extent of glutathione peroxidase activity.
1903284	positive regulation of glutathione peroxidase activity	P	Any process that activates or increases the frequency, rate or extent of glutathione peroxidase activity.
1903285	positive regulation of hydrogen peroxide catabolic process	P	Any process that activates or increases the frequency, rate or extent of hydrogen peroxide catabolic process.
1903286	regulation of potassium ion import	P	Any process that modulates the frequency, rate or extent of potassium ion import.
1903287	negative regulation of potassium ion import	P	Any process that stops, prevents or reduces the frequency, rate or extent of potassium ion import.
1903288	positive regulation of potassium ion import	P	Any process that activates or increases the frequency, rate or extent of potassium ion import.
1903292	protein localization to Golgi membrane	P	A process in which a protein is transported to, or maintained in, a location within a Golgi membrane.
1903293	phosphatase complex	C	A protein complex which is capable of phosphatase activity.
1903294	regulation of glutamate secretion, neurotransmission	P	Any process that modulates the frequency, rate or extent of glutamate secretion, neurotransmission.
1903295	negative regulation of glutamate secretion, neurotransmission	P	Any process that stops, prevents or reduces the frequency, rate or extent of glutamate secretion, neurotransmission.
1903296	positive regulation of glutamate secretion, neurotransmission	P	Any process that activates or increases the frequency, rate or extent of glutamate secretion, where glutamate acts as a neurotransmitter.
1903297	regulation of hypoxia-induced intrinsic apoptotic signaling pathway	P	Any process that modulates the frequency, rate or extent of hypoxia-induced intrinsic apoptotic signaling pathway.
1903298	negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway	P	Any process that stops, prevents or reduces the frequency, rate or extent of hypoxia-induced intrinsic apoptotic signaling pathway.
1903299	regulation of hexokinase activity	P	Any process that modulates the frequency, rate or extent of hexokinase activity.
1903300	negative regulation of hexokinase activity	P	Any process that stops, prevents or reduces the frequency, rate or extent of hexokinase activity.
1903301	positive regulation of hexokinase activity	P	Any process that activates or increases the frequency, rate or extent of hexokinase activity.
1903302	regulation of pyruvate kinase activity	P	Any process that modulates the frequency, rate or extent of pyruvate kinase activity.
1903303	negative regulation of pyruvate kinase activity	P	Any process that stops, prevents or reduces the frequency, rate or extent of pyruvate kinase activity.
1903304	positive regulation of pyruvate kinase activity	P	Any process that activates or increases the frequency, rate or extent of pyruvate kinase activity.
1903305	regulation of regulated secretory pathway	P	Any process that modulates the frequency, rate or extent of regulated secretory pathway.
1903306	negative regulation of regulated secretory pathway	P	Any process that stops, prevents or reduces the frequency, rate or extent of regulated secretory pathway.
1903307	positive regulation of regulated secretory pathway	P	Any process that activates or increases the frequency, rate or extent of regulated secretory pathway.
1903311	regulation of mRNA metabolic process	P	Any process that modulates the frequency, rate or extent of mRNA metabolic process.
1903312	negative regulation of mRNA metabolic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of mRNA metabolic process.
1903313	positive regulation of mRNA metabolic process	P	Any process that activates or increases the frequency, rate or extent of mRNA metabolic process.
1903314	regulation of nitrogen cycle metabolic process	P	Any process that modulates the frequency, rate or extent of nitrogen cycle metabolic process.
1903315	negative regulation of nitrogen cycle metabolic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of nitrogen cycle metabolic process.
1903316	positive regulation of nitrogen cycle metabolic process	P	Any process that activates or increases the frequency, rate or extent of nitrogen cycle metabolic process.
1903317	regulation of protein maturation	P	Any process that modulates the frequency, rate or extent of protein maturation.
1903318	negative regulation of protein maturation	P	Any process that stops, prevents or reduces the frequency, rate or extent of protein maturation.
1903319	positive regulation of protein maturation	P	Any process that activates or increases the frequency, rate or extent of protein maturation.
1903320	regulation of protein modification by small protein conjugation or removal	P	Any process that modulates the frequency, rate or extent of protein modification by small protein conjugation or removal.
1903321	negative regulation of protein modification by small protein conjugation or removal	P	Any process that stops, prevents or reduces the frequency, rate or extent of protein modification by small protein conjugation or removal.
1903322	positive regulation of protein modification by small protein conjugation or removal	P	Any process that activates or increases the frequency, rate or extent of protein modification by small protein conjugation or removal.
1903323	regulation of snoRNA metabolic process	P	Any process that modulates the frequency, rate or extent of snoRNA metabolic process.
1903324	negative regulation of snoRNA metabolic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of snoRNA metabolic process.
1903325	positive regulation of snoRNA metabolic process	P	Any process that activates or increases the frequency, rate or extent of snoRNA metabolic process.
1903326	regulation of tRNA metabolic process	P	Any process that modulates the frequency, rate or extent of tRNA metabolic process.
1903327	negative regulation of tRNA metabolic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of tRNA metabolic process.
1903328	positive regulation of tRNA metabolic process	P	Any process that activates or increases the frequency, rate or extent of tRNA metabolic process.
1903329	regulation of iron-sulfur cluster assembly	P	Any process that modulates the frequency, rate or extent of iron-sulfur cluster assembly.
1903330	negative regulation of iron-sulfur cluster assembly	P	Any process that stops, prevents or reduces the frequency, rate or extent of iron-sulfur cluster assembly.
1903331	positive regulation of iron-sulfur cluster assembly	P	Any process that activates or increases the frequency, rate or extent of iron-sulfur cluster assembly.
1903332	regulation of protein folding	P	Any process that modulates the frequency, rate or extent of protein folding.
1903333	negative regulation of protein folding	P	Any process that stops, prevents or reduces the frequency, rate or extent of protein folding.
1903334	positive regulation of protein folding	P	Any process that activates or increases the frequency, rate or extent of protein folding.
1903335	regulation of vacuolar transport	P	Any process that modulates the frequency, rate or extent of vacuolar transport.
1903336	negative regulation of vacuolar transport	P	Any process that stops, prevents or reduces the frequency, rate or extent of vacuolar transport.
1903337	positive regulation of vacuolar transport	P	Any process that activates or increases the frequency, rate or extent of vacuolar transport.
1903338	regulation of cell wall organization or biogenesis	P	Any process that modulates the frequency, rate or extent of cell wall organization or biogenesis.
1903339	negative regulation of cell wall organization or biogenesis	P	Any process that stops, prevents or reduces the frequency, rate or extent of cell wall organization or biogenesis.
1903340	positive regulation of cell wall organization or biogenesis	P	Any process that activates or increases the frequency, rate or extent of cell wall organization or biogenesis.
1903341	regulation of meiotic DNA double-strand break formation	P	Any process that modulates the frequency, rate or extent of meiotic DNA double-strand break formation.
1903342	negative regulation of meiotic DNA double-strand break formation	P	Any process that stops, prevents or reduces the frequency, rate or extent of meiotic DNA double-strand break formation.
1903343	positive regulation of meiotic DNA double-strand break formation	P	Any process that activates or increases the frequency, rate or extent of meiotic DNA double-strand break formation.
1903344	regulation of protein polyglycylation	P	Any process that modulates the frequency, rate or extent of protein polyglycylation.
1903345	negative regulation of protein polyglycylation	P	Any process that stops, prevents or reduces the frequency, rate or extent of protein polyglycylation.
1903346	positive regulation of protein polyglycylation	P	Any process that activates or increases the frequency, rate or extent of protein polyglycylation.
1903347	negative regulation of bicellular tight junction assembly	P	Any process that stops, prevents or reduces the frequency, rate or extent of tight junction assembly.
1903348	positive regulation of bicellular tight junction assembly	P	Any process that activates or increases the frequency, rate or extent of tight junction assembly.
1903349	omegasome membrane	C	Any membrane that is part of an omegasome.
1903350	response to dopamine	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dopamine stimulus.
1903351	cellular response to dopamine	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dopamine stimulus.
1903352	L-ornithine transmembrane transport	P	The directed movement of L-ornithine across a membrane.
1903353	regulation of nucleus organization	P	Any process that modulates the frequency, rate or extent of nucleus organization.
1903354	regulation of distal tip cell migration	P	Any process that modulates the frequency, rate or extent of distal tip cell migration.
1903355	negative regulation of distal tip cell migration	P	Any process that stops, prevents or reduces the frequency, rate or extent of distal tip cell migration.
1903356	positive regulation of distal tip cell migration	P	Any process that activates or increases the frequency, rate or extent of distal tip cell migration.
1903357	regulation of transcription initiation from RNA polymerase I promoter for nuclear large rRNA transcript	P	Any process that modulates the frequency, rate or extent of transcription initiation from RNA polymerase I promoter for nuclear large rRNA transcript.
1903358	regulation of Golgi organization	P	Any process that modulates the frequency, rate or extent of Golgi organization.
1903359	lateral cortical node assembly	P	The aggregation, arrangement and bonding together of a set of components to form a lateral cortical node.
1903360	protein localization to lateral cortical node	P	A process in which a protein is transported to, or maintained in, a location within a lateral cortical node.
1903361	protein localization to basolateral plasma membrane	P	A process in which a protein is transported to, or maintained in, a location within a basolateral plasma membrane.
1903362	regulation of cellular protein catabolic process	P	Any process that modulates the frequency, rate or extent of cellular protein catabolic process.
1903363	negative regulation of cellular protein catabolic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of cellular protein catabolic process.
1903364	positive regulation of cellular protein catabolic process	P	Any process that activates or increases the frequency, rate or extent of cellular protein catabolic process.
1903365	regulation of fear response	P	Any process that modulates the frequency, rate or extent of fear response.
1903366	negative regulation of fear response	P	Any process that stops, prevents or reduces the frequency, rate or extent of fear response.
1903367	positive regulation of fear response	P	Any process that activates or increases the frequency, rate or extent of fear response.
1903368	regulation of foraging behavior	P	Any process that modulates the frequency, rate or extent of foraging behavior.
1903369	negative regulation of foraging behavior	P	Any process that stops, prevents or reduces the frequency, rate or extent of foraging behavior.
1903370	positive regulation of foraging behavior	P	Any process that activates or increases the frequency, rate or extent of foraging behavior.
1903371	regulation of endoplasmic reticulum tubular network organization	P	Any process that modulates the frequency, rate or extent of endoplasmic reticulum tubular network organization.
1903372	negative regulation of endoplasmic reticulum tubular network organization	P	Any process that stops, prevents or reduces the frequency, rate or extent of endoplasmic reticulum tubular network organization.
1903373	positive regulation of endoplasmic reticulum tubular network organization	P	Any process that activates or increases the frequency, rate or extent of endoplasmic reticulum tubular network organization.
1903374	subarachnoid space development	P	The process whose specific outcome is the progression of a subarachnoid space over time, from its formation to the mature structure.
1903375	facioacoustic ganglion development	P	The process whose specific outcome is the progression of an acoustico-facial VII-VIII ganglion complex over time, from its formation to the mature structure.
1903376	regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway	P	Any process that modulates the frequency, rate or extent of oxidative stress-induced neuron intrinsic apoptotic signaling pathway.
1903377	negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway	P	Any process that stops, prevents or reduces the frequency, rate or extent of oxidative stress-induced neuron intrinsic apoptotic signaling pathway.
1903378	positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway	P	Any process that activates or increases the frequency, rate or extent of oxidative stress-induced neuron intrinsic apoptotic signaling pathway.
1903379	regulation of mitotic chromosome condensation	P	Any process that modulates the frequency, rate or extent of mitotic chromosome condensation.
1903380	positive regulation of mitotic chromosome condensation	P	Any process that activates or increases the frequency, rate or extent of mitotic chromosome condensation.
1903381	regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway	P	Any process that modulates the frequency, rate or extent of an endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway.
1903382	negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway	P	Any process that stops, prevents or reduces the frequency, rate or extent of an endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway.
1903383	regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway	P	Any process that modulates the frequency, rate or extent of a hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway.
1903384	negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway	P	Any process that stops, prevents or reduces the frequency, rate or extent of a hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway.
1903385	regulation of homophilic cell adhesion	P	Any process that modulates the frequency, rate or extent of homophilic cell adhesion.
1903386	negative regulation of homophilic cell adhesion	P	Any process that stops, prevents or reduces the frequency, rate or extent of homophilic cell adhesion.
1903387	positive regulation of homophilic cell adhesion	P	Any process that activates or increases the frequency, rate or extent of homophilic cell adhesion.
1903388	regulation of synaptic vesicle uncoating	P	Any process that modulates the frequency, rate or extent of synaptic vesicle uncoating.
1903389	negative regulation of synaptic vesicle uncoating	P	Any process that stops, prevents or reduces the frequency, rate or extent of synaptic vesicle uncoating.
1903390	positive regulation of synaptic vesicle uncoating	P	Any process that activates or increases the frequency, rate or extent of synaptic vesicle uncoating.
1903391	regulation of adherens junction organization	P	Any process that modulates the frequency, rate or extent of adherens junction organization.
1903392	negative regulation of adherens junction organization	P	Any process that stops, prevents or reduces the frequency, rate or extent of adherens junction organization.
1903393	positive regulation of adherens junction organization	P	Any process that activates or increases the frequency, rate or extent of adherens junction organization.
1903394	protein localization to kinetochore involved in kinetochore assembly	P	Any protein localization to kinetochore that is involved in kinetochore assembly.
1903395	regulation of secondary cell septum biogenesis	P	Any process that modulates the frequency, rate or extent of secondary cell septum biogenesis.
1903396	negative regulation of secondary cell septum biogenesis	P	Any process that stops, prevents or reduces the frequency, rate or extent of secondary cell septum biogenesis.
1903397	positive regulation of secondary cell septum biogenesis	P	Any process that activates or increases the frequency, rate or extent of secondary cell septum biogenesis.
1903398	regulation of m7G(5')pppN diphosphatase activity	P	Any process that modulates the frequency, rate or extent of m7G(5')pppN diphosphatase activity.
1903399	positive regulation of m7G(5')pppN diphosphatase activity	P	Any process that activates or increases the frequency, rate or extent of m7G(5')pppN diphosphatase activity.
1903400	L-arginine transmembrane transport	P	The directed movement of L-arginine across a membrane.
1903401	L-lysine transmembrane transport	P	The directed movement of L-lysine across a membrane.
1903402	regulation of renal phosphate excretion	P	Any process that modulates the frequency, rate or extent of renal phosphate excretion.
1903403	negative regulation of renal phosphate excretion	P	Any process that stops, prevents or reduces the frequency, rate or extent of renal phosphate excretion.
1903404	positive regulation of renal phosphate excretion	P	Any process that activates or increases the frequency, rate or extent of renal phosphate excretion.
1903405	protein localization to nuclear body	P	A process in which a protein is transported to, or maintained in, a location within a nuclear body.
1903406	regulation of sodium:potassium-exchanging ATPase activity	P	Any process that modulates the frequency, rate or extent of sodium:potassium-exchanging ATPase activity.
1903407	negative regulation of sodium:potassium-exchanging ATPase activity	P	Any process that stops, prevents or reduces the frequency, rate or extent of sodium:potassium-exchanging ATPase activity.
1903408	positive regulation of sodium:potassium-exchanging ATPase activity	P	Any process that activates or increases the frequency, rate or extent of sodium:potassium-exchanging ATPase activity.
1903409	reactive oxygen species biosynthetic process	P	The chemical reactions and pathways resulting in the formation of reactive oxygen species, any molecules or ions formed by the incomplete one-electron reduction of oxygen.
1903410	L-lysine import into cell	P	The directed movement of L-lysine into a cell.
1903411	L-ornithine import into cell	P	The directed movement of L-ornithine into a cell.
1903412	response to bile acid	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bile acid stimulus.
1903413	cellular response to bile acid	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bile acid stimulus.
1903414	iron cation export	P	The directed movement of iron cation out of a cell or organelle.
1903415	flavonoid transport from endoplasmic reticulum to plant-type vacuole	P	The directed movement of flavonoid from endoplasmic reticulum to plant-type vacuole.
1903416	response to glycoside	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glycoside stimulus.
1903418	protein localization to plasma membrane of cell tip	P	A process in which a protein is transported to, or maintained in, a location within a plasma membrane of cell tip.
1903419	protein localization to cortical endoplasmic reticulum	P	A process in which a protein is transported to, or maintained in, a location within a cortical endoplasmic reticulum.
1903420	protein localization to endoplasmic reticulum tubular network	P	A process in which a protein is transported to, or maintained in, a location within an endoplasmic reticulum tubular network.
1903421	regulation of synaptic vesicle recycling	P	Any process that modulates the frequency, rate or extent of synaptic vesicle recycling.
1903422	negative regulation of synaptic vesicle recycling	P	Any process that stops, prevents or reduces the frequency, rate or extent of synaptic vesicle recycling.
1903423	positive regulation of synaptic vesicle recycling	P	Any process that activates or increases the frequency, rate or extent of synaptic vesicle recycling.
1903424	fluoride transmembrane transport	P	The directed movement of fluoride across a membrane.
1903425	fluoride transmembrane transporter activity	F	Enables the transfer of fluoride from one side of the membrane to the other.
1903426	regulation of reactive oxygen species biosynthetic process	P	Any process that modulates the frequency, rate or extent of reactive oxygen species biosynthetic process.
1903427	negative regulation of reactive oxygen species biosynthetic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of reactive oxygen species biosynthetic process.
1903428	positive regulation of reactive oxygen species biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of reactive oxygen species biosynthetic process.
1903429	regulation of cell maturation	P	Any process that modulates the frequency, rate or extent of cell maturation.
1903430	negative regulation of cell maturation	P	Any process that stops, prevents or reduces the frequency, rate or extent of cell maturation.
1903431	positive regulation of cell maturation	P	Any process that activates or increases the frequency, rate or extent of cell maturation.
1903432	regulation of TORC1 signaling	P	Any process that modulates the frequency, rate or extent of TORC1 signaling.
1903433	regulation of constitutive secretory pathway	P	Any process that modulates the frequency, rate or extent of constitutive secretory pathway.
1903434	negative regulation of constitutive secretory pathway	P	Any process that stops, prevents or reduces the frequency, rate or extent of constitutive secretory pathway.
1903435	positive regulation of constitutive secretory pathway	P	Any process that activates or increases the frequency, rate or extent of constitutive secretory pathway.
1903436	regulation of mitotic cytokinetic process	P	Any process that modulates the frequency, rate or extent of mitotic cytokinetic process.
1903437	negative regulation of mitotic cytokinetic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of mitotic cytokinetic process.
1903438	positive regulation of mitotic cytokinetic process	P	Any process that activates or increases the frequency, rate or extent of mitotic cytokinetic process.
1903439	calcitonin family receptor complex	C	A protein complex which is capable of calcitonin family receptor activity. Calcitonin family receptors may form dimers, trimers or tetramers; adrenomedullin and amylin receptors have only been observed as dimers so far.
1903440	amylin receptor complex	C	A protein complex which is capable of amylin receptor activity.
1903441	protein localization to ciliary membrane	P	A process in which a protein is transported to, or maintained in, a location within a ciliary membrane.
1903442	response to lipoic acid	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipoic acid stimulus.
1903443	cellular response to lipoic acid	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipoic acid stimulus.
1903444	negative regulation of brown fat cell differentiation	P	Any process that stops, prevents or reduces the frequency, rate or extent of brown fat cell differentiation.
1903445	protein transport from ciliary membrane to plasma membrane	P	The directed movement of protein from ciliary membrane to plasma membrane.
1903446	geraniol metabolic process	P	The chemical reactions and pathways involving geraniol.
1903447	geraniol catabolic process	P	The chemical reactions and pathways resulting in the breakdown of geraniol.
1903448	geraniol biosynthetic process	P	The chemical reactions and pathways resulting in the formation of geraniol.
1903449	androst-4-ene-3,17-dione biosynthetic process	P	The chemical reactions and pathways resulting in the formation of androst-4-ene-3,17-dione.
1903450	regulation of G1 to G0 transition	P	Any process that modulates the frequency, rate or extent of G1 to G0 transition.
1903451	negative regulation of G1 to G0 transition	P	Any process that stops, prevents or reduces the frequency, rate or extent of G1 to G0 transition.
1903452	positive regulation of G1 to G0 transition	P	Any process that activates or increases the frequency, rate or extent of G1 to G0 transition.
1903453	RNA interference involved in olfactory learning	P	Any RNA interference that is involved in olfactory learning.
1903454	regulation of androst-4-ene-3,17-dione biosynthetic process	P	Any process that modulates the frequency, rate or extent of androst-4-ene-3,17-dione biosynthetic process.
1903455	negative regulation of androst-4-ene-3,17-dione biosynthetic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of androst-4-ene-3,17-dione biosynthetic process.
1903456	positive regulation of androst-4-ene-3,17-dione biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of androst-4-ene-3,17-dione biosynthetic process.
1903457	lactate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of lactate.
1903459	mitotic DNA replication lagging strand elongation	P	Any lagging strand elongation that is involved in mitotic cell cycle DNA replication.
1903460	mitotic DNA replication leading strand elongation	P	Any leading strand elongation that is involved in mitotic cell cycle DNA replication.
1903461	Okazaki fragment processing involved in mitotic DNA replication	P	Any DNA replication, Okazaki fragment processing that is involved in mitotic cell cycle DNA replication.
1903463	regulation of mitotic cell cycle DNA replication	P	Any process that modulates the frequency, rate or extent of mitotic cell cycle DNA replication.
1903464	negative regulation of mitotic cell cycle DNA replication	P	Any process that stops, prevents or reduces the frequency, rate or extent of mitotic cell cycle DNA replication.
1903465	positive regulation of mitotic cell cycle DNA replication	P	Any process that activates or increases the frequency, rate or extent of mitotic cell cycle DNA replication.
1903466	regulation of mitotic DNA replication initiation	P	Any process that modulates the frequency, rate or extent of DNA replication initiation involved in mitotic DNA replication.
1903467	negative regulation of mitotic DNA replication initiation	P	Any process that stops, prevents or reduces the frequency, rate or extent of DNA replication initiation involved in mitotic DNA replication.
1903468	positive regulation of DNA replication initiation	P	Any process that activates or increases the frequency, rate or extent of DNA replication initiation involved in mitotic DNA replication.
1903469	removal of RNA primer involved in mitotic DNA replication	P	Any DNA replication, removal of RNA primer that is involved in mitotic cell cycle DNA replication.
1903471	regulation of mitotic actomyosin contractile ring contraction	P	Any process that modulates the frequency, rate or extent of mitotic actomyosin contractile ring contraction.
1903472	negative regulation of mitotic actomyosin contractile ring contraction	P	Any process that stops, prevents or reduces the frequency, rate or extent of mitotic actomyosin contractile ring contraction.
1903473	positive regulation of mitotic actomyosin contractile ring contraction	P	Any process that activates or increases the frequency, rate or extent of mitotic actomyosin contractile ring contraction.
1903474	maintenance of mitotic actomyosin contractile ring localization	P	Any maintenance of actomyosin contractile ring localization that is involved in mitotic cell cycle.
1903475	mitotic actomyosin contractile ring assembly	P	Any actomyosin contractile ring assembly that is involved in mitotic cytokinesis.
1903476	protein localization to cell division site involved in mitotic actomyosin contractile ring assembly	P	Any protein localization to cell division site that is involved in mitotic actomyosin contractile ring assembly.
1903477	mitotic contractile ring actin filament bundle assembly	P	Any actin filament bundle assembly that is involved in mitotic actomyosin contractile ring assembly.
1903478	actin filament bundle convergence involved in mitotic contractile ring assembly	P	Any actin filament bundle convergence that is involved in mitotic actomyosin contractile ring assembly.
1903479	mitotic actomyosin contractile ring assembly actin filament organization	P	Any actin filament organization that is involved in mitotic actomyosin contractile ring assembly.
1903480	regulation of actin filament organization involved in mitotic actomyosin contractile ring assembly	P	Any process that modulates the frequency, rate or extent of actin filament organization involved in mitotic actomyosin contractile ring assembly.
1903481	negative regulation of actin filament organization involved in mitotic actomyosin contractile ring assembly	P	Any process that stops, prevents or reduces the frequency, rate or extent of actin filament organization involved in mitotic actomyosin contractile ring assembly.
1903482	positive regulation of actin filament organization involved in mitotic actomyosin contractile ring assembly	P	Any process that activates or increases the frequency, rate or extent of actin filament organization involved in mitotic actomyosin contractile ring assembly.
1903483	regulation of maintenance of mitotic actomyosin contractile ring localization	P	Any process that modulates the frequency, rate or extent of maintenance of mitotic actomyosin contractile ring localization.
1903484	negative regulation of maintenance of mitotic actomyosin contractile ring localization	P	Any process that stops, prevents or reduces the frequency, rate or extent of maintenance of mitotic actomyosin contractile ring localization.
1903485	positive regulation of maintenance of mitotic actomyosin contractile ring localization	P	Any process that activates or increases the frequency, rate or extent of maintenance of mitotic actomyosin contractile ring localization.
1903486	establishment of mitotic actomyosin contractile ring localization	P	Any establishment of actomyosin contractile ring localization that is involved in mitotic cell cycle.
1903487	regulation of lactation	P	Any process that modulates the frequency, rate or extent of lactation.
1903488	negative regulation of lactation	P	Any process that stops, prevents or reduces the frequency, rate or extent of lactation.
1903489	positive regulation of lactation	P	Any process that activates or increases the frequency, rate or extent of lactation.
1903490	positive regulation of mitotic cytokinesis	P	Any process that activates or increases the frequency, rate or extent of mitotic cytokinesis.
1903491	response to simvastatin	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a simvastatin stimulus. Simvastatin is a statin used as a cholesterol-lowering and anti-cardiovascular disease drug.
1903492	response to acetylsalicylate	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an aspirin (acetylsalicylate) stimulus. Aspirin is a non-steroidal anti-inflammatory drug with moA cyclooxygenase inhibitor activity.
1903493	response to clopidogrel	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a clopidogrel stimulus. Clopidogrel is a is an oral, thienopyridine-class antiplatelet agent used to inhibit blood clots in coronary artery disease, peripheral vascular disease, and cerebrovascular disease.
1903494	response to dehydroepiandrosterone	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dehydroepiandrosterone stimulus.
1903495	cellular response to dehydroepiandrosterone	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dehydroepiandrosterone stimulus.
1903496	response to 11-deoxycorticosterone	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 11-deoxycorticosterone stimulus.
1903497	cellular response to 11-deoxycorticosterone	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 11-deoxycorticosterone stimulus.
1903498	bundle sheath cell differentiation	P	The process in which a relatively unspecialized cell acquires the specialized features of a bundle sheath cell.
1903499	regulation of mitotic actomyosin contractile ring assembly	P	Any process that modulates the frequency, rate or extent of mitotic actomyosin contractile ring assembly.
1903500	negative regulation of mitotic actomyosin contractile ring assembly	P	Any process that stops, prevents or reduces the frequency, rate or extent of mitotic actomyosin contractile ring assembly.
1903501	positive regulation of mitotic actomyosin contractile ring assembly	P	Any process that activates or increases the frequency, rate or extent of mitotic actomyosin contractile ring assembly.
1903502	translation repressor complex	C	A protein complex which is capable of translation repressor activity.
1903503	ATPase inhibitor complex	C	A protein complex which is capable of ATPase inhibitor activity.
1903504	regulation of mitotic spindle checkpoint	P	Any process that modulates the frequency, rate or extent of mitotic spindle checkpoint.
1903505	regulation of establishment of actomyosin contractile ring localization involved in mitotic cell cycle	P	Any process that modulates the frequency, rate or extent of establishment of actomyosin contractile ring localization involved in mitotic cell cycle.
1903506	regulation of nucleic acid-templated transcription	P	Any process that modulates the frequency, rate or extent of nucleic acid-templated transcription.
1903507	negative regulation of nucleic acid-templated transcription	P	Any process that stops, prevents or reduces the frequency, rate or extent of nucleic acid-templated transcription.
1903508	positive regulation of nucleic acid-templated transcription	P	Any process that activates or increases the frequency, rate or extent of nucleic acid-templated transcription.
1903509	liposaccharide metabolic process	P	The chemical reactions and pathways involving liposaccharide.
1903510	mucopolysaccharide metabolic process	P	The chemical reactions and pathways involving mucopolysaccharide.
1903511	orotic acid metabolic process	P	The chemical reactions and pathways involving orotic acid.
1903512	phytanic acid metabolic process	P	The chemical reactions and pathways involving phytanic acid.
1903513	endoplasmic reticulum to cytosol transport	P	The directed movement of substances from endoplasmic reticulum to cytosol.
1903514	calcium ion transport from endoplasmic reticulum to cytosol	P	The directed movement of calcium ion from endoplasmic reticulum to cytosol.
1903515	calcium ion transport from cytosol to endoplasmic reticulum	P	The directed movement of calcium ion from cytosol to endoplasmic reticulum.
1903516	regulation of single strand break repair	P	Any process that modulates the frequency, rate or extent of single strand break repair.
1903517	negative regulation of single strand break repair	P	Any process that stops, prevents or reduces the frequency, rate or extent of single strand break repair.
1903518	positive regulation of single strand break repair	P	Any process that activates or increases the frequency, rate or extent of single strand break repair.
1903519	regulation of mammary gland involution	P	Any process that modulates the frequency, rate or extent of mammary gland involution.
1903520	negative regulation of mammary gland involution	P	Any process that stops, prevents or reduces the frequency, rate or extent of mammary gland involution.
1903521	positive regulation of mammary gland involution	P	Any process that activates or increases the frequency, rate or extent of mammary gland involution.
1903522	regulation of blood circulation	P	Any process that modulates the frequency, rate or extent of blood circulation.
1903523	negative regulation of blood circulation	P	Any process that stops, prevents or reduces the frequency, rate or extent of blood circulation.
1903524	positive regulation of blood circulation	P	Any process that activates or increases the frequency, rate or extent of blood circulation.
1903525	regulation of membrane tubulation	P	Any process that modulates the frequency, rate or extent of membrane tubulation.
1903526	negative regulation of membrane tubulation	P	Any process that stops, prevents or reduces the frequency, rate or extent of membrane tubulation.
1903527	positive regulation of membrane tubulation	P	Any process that activates or increases the frequency, rate or extent of membrane tubulation.
1903528	regulation of dCDP biosynthetic process	P	Any process that modulates the frequency, rate or extent of dCDP biosynthetic process.
1903529	negative regulation of dCDP biosynthetic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of dCDP biosynthetic process.
1903530	regulation of secretion by cell	P	Any process that modulates the frequency, rate or extent of secretion by cell.
1903531	negative regulation of secretion by cell	P	Any process that stops, prevents or reduces the frequency, rate or extent of secretion by cell.
1903532	positive regulation of secretion by cell	P	Any process that activates or increases the frequency, rate or extent of secretion by cell.
1903533	regulation of protein targeting	P	Any process that modulates the frequency, rate or extent of protein targeting.
1903534	regulation of lactose biosynthetic process	P	Any process that modulates the frequency, rate or extent of lactose biosynthetic process.
1903535	negative regulation of lactose biosynthetic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of lactose biosynthetic process.
1903536	positive regulation of lactose biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of lactose biosynthetic process.
1903537	meiotic cell cycle process involved in oocyte maturation	P	Any meiotic cell cycle process that is involved in oocyte maturation.
1903538	regulation of meiotic cell cycle process involved in oocyte maturation	P	Any process that modulates the frequency, rate or extent of meiotic cell cycle process involved in oocyte maturation.
1903539	protein localization to postsynaptic membrane	P	A process in which a protein is transported to, or maintained in, a location within a postsynaptic membrane.
1903540	establishment of protein localization to postsynaptic membrane	P	The directed movement of a protein to a specific location in a postsynaptic membrane.
1903541	regulation of exosomal secretion	P	Any process that modulates the frequency, rate or extent of exosomal secretion.
1903542	negative regulation of exosomal secretion	P	Any process that stops, prevents or reduces the frequency, rate or extent of exosomal secretion.
1903543	positive regulation of exosomal secretion	P	Any process that activates or increases the frequency, rate or extent of exosomal secretion.
1903544	response to butyrate	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a butyrate stimulus.
1903545	cellular response to butyrate	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a butyrate stimulus.
1903546	protein localization to photoreceptor outer segment	P	A process in which a protein is transported to, or maintained in, a location within a photoreceptor outer segment.
1903547	regulation of growth hormone activity	P	Any process that modulates the frequency, rate or extent of growth hormone activity.
1903548	negative regulation of growth hormone activity	P	Any process that stops, prevents or reduces the frequency, rate or extent of growth hormone activity.
1903549	positive regulation of growth hormone activity	P	Any process that activates or increases the frequency, rate or extent of growth hormone activity.
1903551	regulation of extracellular exosome assembly	P	Any process that modulates the frequency, rate or extent of extracellular vesicular exosome assembly.
1903552	negative regulation of extracellular exosome assembly	P	Any process that stops, prevents or reduces the frequency, rate or extent of extracellular vesicular exosome assembly.
1903553	positive regulation of extracellular exosome assembly	P	Any process that activates or increases the frequency, rate or extent of extracellular vesicular exosome assembly.
1903554	G-protein coupled receptor signaling pathway involved in defense response to Gram-negative bacterium	P	Any G-protein coupled receptor signaling pathway that is involved in defense response to Gram-negative bacterium.
1903555	regulation of tumor necrosis factor superfamily cytokine production	P	Any process that modulates the frequency, rate or extent of tumor necrosis factor superfamily cytokine production.
1903556	negative regulation of tumor necrosis factor superfamily cytokine production	P	Any process that stops, prevents or reduces the frequency, rate or extent of tumor necrosis factor superfamily cytokine production.
1903557	positive regulation of tumor necrosis factor superfamily cytokine production	P	Any process that activates or increases the frequency, rate or extent of tumor necrosis factor superfamily cytokine production.
1903558	3-cyano-L-alanine metabolic process	P	The chemical reactions and pathways involving 3-cyano-L-alanine.
1903559	3-cyano-L-alanine catabolic process	P	The chemical reactions and pathways resulting in the breakdown of 3-cyano-L-alanine.
1903560	3-cyano-L-alanine biosynthetic process	P	The chemical reactions and pathways resulting in the formation of 3-cyano-L-alanine.
1903561	extracellular vesicle	C	Any vesicle that is part of the extracellular region.
1903562	microtubule bundle formation involved in mitotic spindle midzone assembly	P	Any microtubule bundle formation that is involved in spindle midzone assembly involved in mitosis.
1903563	microtubule bundle formation involved in horsetail-astral microtubule organization	P	Any microtubule bundle formation that is involved in horsetail-astral microtubule organization.
1903564	regulation of protein localization to cilium	P	Any process that modulates the frequency, rate or extent of protein localization to cilium.
1903565	negative regulation of protein localization to cilium	P	Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cilium.
1903566	positive regulation of protein localization to cilium	P	Any process that activates or increases the frequency, rate or extent of protein localization to cilium.
1903567	regulation of protein localization to ciliary membrane	P	Any process that modulates the frequency, rate or extent of protein localization to ciliary membrane.
1903568	negative regulation of protein localization to ciliary membrane	P	Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to ciliary membrane.
1903569	positive regulation of protein localization to ciliary membrane	P	Any process that activates or increases the frequency, rate or extent of protein localization to ciliary membrane.
1903570	regulation of protein kinase D signaling	P	Any process that modulates the frequency, rate or extent of protein kinase D signaling.
1903571	negative regulation of protein kinase D signaling	P	Any process that stops, prevents or reduces the frequency, rate or extent of protein kinase D signaling.
1903572	positive regulation of protein kinase D signaling	P	Any process that activates or increases the frequency, rate or extent of protein kinase D signaling.
1903573	negative regulation of response to endoplasmic reticulum stress	P	Any process that stops, prevents or reduces the frequency, rate or extent of a response to endoplasmic reticulum stress.
1903574	negative regulation of cellular response to amino acid starvation	P	Any process that stops, prevents or reduces the frequency, rate or extent of a cellular response to amino acid starvation.
1903575	cornified envelope assembly	P	The aggregation, arrangement and bonding together of a set of components to form a cornified envelope.
1903576	response to L-arginine	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-arginine stimulus.
1903577	cellular response to L-arginine	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-arginine stimulus.
1903578	regulation of ATP metabolic process	P	Any process that modulates the frequency, rate or extent of ATP metabolic process.
1903579	negative regulation of ATP metabolic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of ATP metabolic process.
1903580	positive regulation of ATP metabolic process	P	Any process that activates or increases the frequency, rate or extent of ATP metabolic process.
1903581	regulation of basophil degranulation	P	Any process that modulates the frequency, rate or extent of basophil degranulation.
1903582	negative regulation of basophil degranulation	P	Any process that stops, prevents or reduces the frequency, rate or extent of basophil degranulation.
1903583	positive regulation of basophil degranulation	P	Any process that activates or increases the frequency, rate or extent of basophil degranulation.
1903584	regulation of histone deubiquitination	P	Any process that modulates the frequency, rate or extent of histone deubiquitination.
1903585	negative regulation of histone deubiquitination	P	Any process that stops, prevents or reduces the frequency, rate or extent of histone deubiquitination.
1903586	positive regulation of histone deubiquitination	P	Any process that activates or increases the frequency, rate or extent of histone deubiquitination.
1903587	regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis	P	Any process that modulates the frequency, rate or extent of blood vessel endothelial cell proliferation involved in sprouting angiogenesis.
1903588	negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis	P	Any process that stops, prevents or reduces the frequency, rate or extent of blood vessel endothelial cell proliferation involved in sprouting angiogenesis.
1903589	positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis	P	Any process that activates or increases the frequency, rate or extent of blood vessel endothelial cell proliferation involved in sprouting angiogenesis.
1903590	regulation of lysozyme activity	P	Any process that modulates the frequency, rate or extent of lysozyme activity.
1903591	negative regulation of lysozyme activity	P	Any process that stops, prevents or reduces the frequency, rate or extent of lysozyme activity.
1903592	positive regulation of lysozyme activity	P	Any process that activates or increases the frequency, rate or extent of lysozyme activity.
1903593	regulation of histamine secretion by mast cell	P	Any process that modulates the frequency, rate or extent of histamine secretion by mast cell.
1903594	negative regulation of histamine secretion by mast cell	P	Any process that stops, prevents or reduces the frequency, rate or extent of histamine secretion by mast cell.
1903595	positive regulation of histamine secretion by mast cell	P	Any process that activates or increases the frequency, rate or extent of histamine secretion by mast cell.
1903596	regulation of gap junction assembly	P	Any process that modulates the frequency, rate or extent of gap junction assembly.
1903597	negative regulation of gap junction assembly	P	Any process that stops, prevents or reduces the frequency, rate or extent of gap junction assembly.
1903598	positive regulation of gap junction assembly	P	Any process that activates or increases the frequency, rate or extent of gap junction assembly.
1903599	positive regulation of mitophagy	P	Any process that activates or increases the frequency, rate or extent of mitochondrion degradation.
1903600	glutaminase complex	C	A protein complex which is capable of glutaminase activity.
1903601	thermospermine metabolic process	P	The chemical reactions and pathways involving thermospermine.
1903602	thermospermine catabolic process	P	The chemical reactions and pathways resulting in the breakdown of thermospermine.
1903603	thermospermine biosynthetic process	P	The chemical reactions and pathways resulting in the formation of thermospermine.
1903604	cytochrome metabolic process	P	The chemical reactions and pathways involving a cytochrome.
1903605	cytochrome biosynthetic process	P	The chemical reactions and pathways resulting in the formation of a cytochrome.
1903606	cytochrome c metabolic process	P	The chemical reactions and pathways involving cytochrome c.
1903607	cytochrome c biosynthetic process	P	The chemical reactions and pathways resulting in the formation of cytochrome c.
1903608	protein localization to cytoplasmic stress granule	P	A process in which a protein is transported to, or maintained in, a location within a cytoplasmic stress granule.
1903609	negative regulation of inward rectifier potassium channel activity	P	Any process that stops, prevents or reduces the frequency, rate or extent of inward rectifier potassium channel activity.
1903610	regulation of calcium-dependent ATPase activity	P	Any process that modulates the frequency, rate or extent of calcium-dependent ATPase activity.
1903611	negative regulation of calcium-dependent ATPase activity	P	Any process that stops, prevents or reduces the frequency, rate or extent of calcium-dependent ATPase activity.
1903612	positive regulation of calcium-dependent ATPase activity	P	Any process that activates or increases the frequency, rate or extent of calcium-dependent ATPase activity.
1903613	regulation of protein tyrosine phosphatase activity	P	Any process that modulates the frequency, rate or extent of protein tyrosine phosphatase activity.
1903614	negative regulation of protein tyrosine phosphatase activity	P	Any process that stops, prevents or reduces the frequency, rate or extent of protein tyrosine phosphatase activity.
1903615	positive regulation of protein tyrosine phosphatase activity	P	Any process that activates or increases the frequency, rate or extent of protein tyrosine phosphatase activity.
1903616	MAPK cascade involved in axon regeneration	P	Any MAPK cascade that is involved in axon regeneration.
1903617	positive regulation of mitotic cytokinesis, site selection	P	Any process that activates or increases the frequency, rate or extent of mitotic cytokinesis, site selection.
1903618	regulation of transdifferentiation	P	Any process that modulates the frequency, rate or extent of transdifferentiation.
1903619	negative regulation of transdifferentiation	P	Any process that stops, prevents or reduces the frequency, rate or extent of transdifferentiation.
1903620	positive regulation of transdifferentiation	P	Any process that activates or increases the frequency, rate or extent of transdifferentiation.
1903621	protein localization to photoreceptor connecting cilium	P	A process in which a protein is transported to, or maintained in, a location within a photoreceptor connecting cilium.
1903622	regulation of RNA polymerase III activity	P	Any process that modulates the frequency, rate or extent of RNA polymerase III activity.
1903623	negative regulation of RNA polymerase III activity	P	Any process that stops, prevents or reduces the frequency, rate or extent of RNA polymerase III activity.
1903624	regulation of DNA catabolic process	P	Any process that modulates the frequency, rate or extent of DNA catabolic process.
1903625	negative regulation of DNA catabolic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of DNA catabolic process.
1903626	positive regulation of DNA catabolic process	P	Any process that activates or increases the frequency, rate or extent of DNA catabolic process.
1903627	regulation of dUTP diphosphatase activity	P	Any process that modulates the frequency, rate or extent of dUTP diphosphatase activity.
1903628	negative regulation of dUTP diphosphatase activity	P	Any process that stops, prevents or reduces the frequency, rate or extent of dUTP diphosphatase activity.
1903629	positive regulation of dUTP diphosphatase activity	P	Any process that activates or increases the frequency, rate or extent of dUTP diphosphatase activity.
1903630	regulation of aminoacyl-tRNA ligase activity	P	Any process that modulates the frequency, rate or extent of aminoacyl-tRNA ligase activity.
1903631	negative regulation of aminoacyl-tRNA ligase activity	P	Any process that stops, prevents or reduces the frequency, rate or extent of aminoacyl-tRNA ligase activity.
1903632	positive regulation of aminoacyl-tRNA ligase activity	P	Any process that activates or increases the frequency, rate or extent of aminoacyl-tRNA ligase activity.
1903633	regulation of leucine-tRNA ligase activity	P	Any process that modulates the frequency, rate or extent of leucine-tRNA ligase activity.
1903634	negative regulation of leucine-tRNA ligase activity	P	Any process that stops, prevents or reduces the frequency, rate or extent of leucine-tRNA ligase activity.
1903635	positive regulation of leucine-tRNA ligase activity	P	Any process that activates or increases the frequency, rate or extent of leucine-tRNA ligase activity.
1903636	regulation of protein import into mitochondrial outer membrane	P	Any process that modulates the frequency, rate or extent of protein import into mitochondrial outer membrane.
1903637	negative regulation of protein import into mitochondrial outer membrane	P	Any process that stops, prevents or reduces the frequency, rate or extent of protein import into mitochondrial outer membrane.
1903638	positive regulation of protein import into mitochondrial outer membrane	P	Any process that activates or increases the frequency, rate or extent of protein import into mitochondrial outer membrane.
1903639	regulation of gastrin-induced gastric acid secretion	P	Any process that modulates the frequency, rate or extent of gastrin-induced gastric acid secretion.
1903640	negative regulation of gastrin-induced gastric acid secretion	P	Any process that stops, prevents or reduces the frequency, rate or extent of gastrin-induced gastric acid secretion.
1903641	positive regulation of gastrin-induced gastric acid secretion	P	Any process that activates or increases the frequency, rate or extent of gastrin-induced gastric acid secretion.
1903642	regulation of recombination hotspot binding	P	Any process that modulates the frequency, rate or extent of recombination hotspot binding.
1903643	positive regulation of recombination hotspot binding	P	Any process that activates or increases the frequency, rate or extent of recombination hotspot binding.
1903644	regulation of chaperone-mediated protein folding	P	Any process that modulates the frequency, rate or extent of chaperone-mediated protein folding.
1903645	negative regulation of chaperone-mediated protein folding	P	Any process that stops, prevents or reduces the frequency, rate or extent of chaperone-mediated protein folding.
1903646	positive regulation of chaperone-mediated protein folding	P	Any process that activates or increases the frequency, rate or extent of chaperone-mediated protein folding.
1903647	negative regulation of chlorophyll catabolic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of chlorophyll catabolic process.
1903648	positive regulation of chlorophyll catabolic process	P	Any process that activates or increases the frequency, rate or extent of chlorophyll catabolic process.
1903649	regulation of cytoplasmic transport	P	Any process that modulates the frequency, rate or extent of cytoplasmic transport.
1903650	negative regulation of cytoplasmic transport	P	Any process that stops, prevents or reduces the frequency, rate or extent of cytoplasmic transport.
1903651	positive regulation of cytoplasmic transport	P	Any process that activates or increases the frequency, rate or extent of cytoplasmic transport.
1903652	modulation by virus of host cytoplasmic transport	P	Modulation by an infecting virus of host cytoplasmic transport.
1903653	modulation by symbiont of host cell motility	P	Modulation of host cell motility by a symbiont of that host.
1903654	phosphorylation of RNA polymerase II C-terminal domain serine 5 residues involved in positive regulation of transcription elongation from RNA polymerase II promoter	P	Any phosphorylation of RNA polymerase II C-terminal domain serine 5 residues that is involved in positive regulation of transcription elongation from RNA polymerase II promoter.
1903655	phosphorylation of RNA polymerase II C-terminal domain serine 2 residues involved in positive regulation of transcription elongation from RNA polymerase II promoter	P	Any phosphorylation of RNA polymerase II C-terminal domain serine 2 residues that is involved in positive regulation of transcription elongation from RNA polymerase II promoter.
1903656	regulation of type IV pilus biogenesis	P	Any process that modulates the frequency, rate or extent of type IV pilus biogenesis.
1903657	negative regulation of type IV pilus biogenesis	P	Any process that stops, prevents or reduces the frequency, rate or extent of type IV pilus biogenesis.
1903658	positive regulation of type IV pilus biogenesis	P	Any process that activates or increases the frequency, rate or extent of type IV pilus biogenesis.
1903659	regulation of complement-dependent cytotoxicity	P	Any process that modulates the frequency, rate or extent of complement-dependent cytotoxicity.
1903660	negative regulation of complement-dependent cytotoxicity	P	Any process that stops, prevents or reduces the frequency, rate or extent of complement-dependent cytotoxicity.
1903661	positive regulation of complement-dependent cytotoxicity	P	Any process that activates or increases the frequency, rate or extent of complement-dependent cytotoxicity.
1903662	L-altrarate metabolic process	P	The chemical reactions and pathways involving L-altrarate.
1903663	L-altrarate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of L-altrarate.
1903664	regulation of asexual reproduction	P	Any process that modulates the frequency, rate or extent of asexual reproduction.
1903665	negative regulation of asexual reproduction	P	Any process that stops, prevents or reduces the frequency, rate or extent of asexual reproduction.
1903666	positive regulation of asexual reproduction	P	Any process that activates or increases the frequency, rate or extent of asexual reproduction.
1903667	regulation of chemorepellent activity	P	Any process that modulates the frequency, rate or extent of chemorepellent activity.
1903668	negative regulation of chemorepellent activity	P	Any process that stops, prevents or reduces the frequency, rate or extent of chemorepellent activity.
1903669	positive regulation of chemorepellent activity	P	Any process that activates or increases the frequency, rate or extent of chemorepellent activity.
1903670	regulation of sprouting angiogenesis	P	Any process that modulates the frequency, rate or extent of sprouting angiogenesis.
1903671	negative regulation of sprouting angiogenesis	P	Any process that stops, prevents or reduces the frequency, rate or extent of sprouting angiogenesis.
1903672	positive regulation of sprouting angiogenesis	P	Any process that activates or increases the frequency, rate or extent of sprouting angiogenesis.
1903673	mitotic cleavage furrow formation	P	Any cleavage furrow formation that is involved in mitotic cell cycle.
1903674	regulation of cap-dependent translational initiation	P	Any process that modulates the frequency, rate or extent of cap-dependent translational initiation.
1903675	negative regulation of cap-dependent translational initiation	P	Any process that stops, prevents or reduces the frequency, rate or extent of cap-dependent translational initiation.
1903676	positive regulation of cap-dependent translational initiation	P	Any process that activates or increases the frequency, rate or extent of cap-dependent translational initiation.
1903677	regulation of cap-independent translational initiation	P	Any process that modulates the frequency, rate or extent of cap-independent translational initiation.
1903678	negative regulation of cap-independent translational initiation	P	Any process that stops, prevents or reduces the frequency, rate or extent of cap-independent translational initiation.
1903679	positive regulation of cap-independent translational initiation	P	Any process that activates or increases the frequency, rate or extent of cap-independent translational initiation.
1903680	acinar cell of sebaceous gland differentiation	P	The process in which a relatively unspecialized cell acquires the specialized features of an acinar cell of sebaceous gland.
1903681	regulation of epithelial cell-cell adhesion involved in epithelium migration	P	Any process that modulates the frequency, rate or extent of epithelial cell-cell adhesion involved in epithelium migration.
1903682	negative regulation of epithelial cell-cell adhesion involved in epithelium migration	P	Any process that stops, prevents or reduces the frequency, rate or extent of epithelial cell-cell adhesion involved in epithelium migration.
1903683	positive regulation of epithelial cell-cell adhesion involved in epithelium migration	P	Any process that activates or increases the frequency, rate or extent of epithelial cell-cell adhesion involved in epithelium migration.
1903684	regulation of border follicle cell migration	P	Any process that modulates the frequency, rate or extent of border follicle cell migration.
1903687	negative regulation of border follicle cell migration	P	Any process that stops, prevents or reduces the frequency, rate or extent of border follicle cell migration.
1903688	positive regulation of border follicle cell migration	P	Any process that activates or increases the frequency, rate or extent of border follicle cell migration.
1903689	regulation of wound healing, spreading of epidermal cells	P	Any process that modulates the frequency, rate or extent of wound healing, spreading of epidermal cells.
1903690	negative regulation of wound healing, spreading of epidermal cells	P	Any process that stops, prevents or reduces the frequency, rate or extent of wound healing, spreading of epidermal cells.
1903691	positive regulation of wound healing, spreading of epidermal cells	P	Any process that activates or increases the frequency, rate or extent of wound healing, spreading of epidermal cells.
1903692	methionine import into cell	P	The directed movement of methionine into a cell.
1903693	regulation of mitotic G1 cell cycle arrest in response to nitrogen starvation	P	Any process that modulates the frequency, rate or extent of mitotic G1 cell cycle arrest in response to nitrogen starvation.
1903694	positive regulation of mitotic G1 cell cycle arrest in response to nitrogen starvation	P	Any process that activates or increases the frequency, rate or extent of mitotic G1 cell cycle arrest in response to nitrogen starvation.
1903695	MAPK cascade involved in ascospore formation	P	Any MAPK cascade that is involved in ascospore formation.
1903696	protein localization to horsetail-astral microtubule array	P	A process in which a protein is transported to, or maintained in, a location within a horsetail-astral microtubule array.
1903697	negative regulation of microvillus assembly	P	Any process that stops, prevents or reduces the frequency, rate or extent of microvillus assembly.
1903698	positive regulation of microvillus assembly	P	Any process that activates or increases the frequency, rate or extent of microvillus assembly.
1903699	tarsal gland development	P	The process whose specific outcome is the progression of a tarsal gland over time, from its formation to the mature structure.
1903700	caecum development	P	The process whose specific outcome is the progression of a caecum over time, from its formation to the mature structure.
1903701	substantia propria of cornea development	P	The process whose specific outcome is the progression of a substantia propria of cornea over time, from its formation to the mature structure.
1903702	esophagus development	P	The process whose specific outcome is the progression of an esophagus over time, from its formation to the mature structure.
1903703	enterocyte differentiation	P	The process in which a relatively unspecialized cell acquires the specialized features of an enterocyte.
1903704	negative regulation of production of siRNA involved in RNA interference	P	Any process that stops, prevents or reduces the frequency, rate or extent of production of siRNA involved in RNA interference.
1903705	positive regulation of production of siRNA involved in RNA interference	P	Any process that activates or increases the frequency, rate or extent of production of siRNA involved in RNA interference.
1903706	regulation of hemopoiesis	P	Any process that modulates the frequency, rate or extent of hemopoiesis.
1903707	negative regulation of hemopoiesis	P	Any process that stops, prevents or reduces the frequency, rate or extent of hemopoiesis.
1903708	positive regulation of hemopoiesis	P	Any process that activates or increases the frequency, rate or extent of hemopoiesis.
1903709	uterine gland development	P	The process whose specific outcome is the progression of an uterine gland over time, from its formation to the mature structure.
1903710	spermine transmembrane transport	P	The directed movement of spermine across a membrane.
1903711	spermidine transmembrane transport	P	The directed movement of spermidine across a membrane.
1903712	cysteine transmembrane transport	P	The directed movement of cysteine across a membrane.
1903713	asparagine transmembrane transport	P	The directed movement of asparagine across a membrane.
1903714	isoleucine transmembrane transport	P	The directed movement of isoleucine across a membrane.
1903715	regulation of aerobic respiration	P	Any process that modulates the frequency, rate or extent of aerobic respiration.
1903716	guanine transmembrane transport	P	The directed movement of guanine across a membrane.
1903717	response to ammonia	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ammonia stimulus.
1903718	cellular response to ammonia	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ammonia stimulus.
1903719	regulation of I-kappaB phosphorylation	P	Any process that modulates the frequency, rate or extent of I-kappaB phosphorylation.
1903720	negative regulation of I-kappaB phosphorylation	P	Any process that stops, prevents or reduces the frequency, rate or extent of I-kappaB phosphorylation.
1903721	positive regulation of I-kappaB phosphorylation	P	Any process that activates or increases the frequency, rate or extent of I-kappaB phosphorylation.
1903722	regulation of centriole elongation	P	Any process that modulates the frequency, rate or extent of centriole elongation.
1903723	negative regulation of centriole elongation	P	Any process that stops, prevents or reduces the frequency, rate or extent of centriole elongation.
1903724	positive regulation of centriole elongation	P	Any process that activates or increases the frequency, rate or extent of centriole elongation.
1903725	regulation of phospholipid metabolic process	P	Any process that modulates the frequency, rate or extent of phospholipid metabolic process.
1903726	negative regulation of phospholipid metabolic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of phospholipid metabolic process.
1903727	positive regulation of phospholipid metabolic process	P	Any process that activates or increases the frequency, rate or extent of phospholipid metabolic process.
1903728	luteal cell differentiation	P	The process in which a relatively unspecialized cell acquires the specialized features of a luteal cell. Large luteal cells develop from granulosa cells. Small luteal cells develop from theca cells.
1903729	regulation of plasma membrane organization	P	Any process that modulates the frequency, rate or extent of plasma membrane organization.
1903730	regulation of phosphatidate phosphatase activity	P	Any process that modulates the frequency, rate or extent of phosphatidate phosphatase activity.
1903740	positive regulation of phosphatidate phosphatase activity	P	Any process that activates or increases the frequency, rate or extent of phosphatidate phosphatase activity.
1903741	negative regulation of phosphatidate phosphatase activity	P	Any process that stops, prevents or reduces the frequency, rate or extent of phosphatidate phosphatase activity.
1903742	regulation of anterograde synaptic vesicle transport	P	Any process that modulates the frequency, rate or extent of anterograde synaptic vesicle transport.
1903743	negative regulation of anterograde synaptic vesicle transport	P	Any process that stops, prevents or reduces the frequency, rate or extent of anterograde synaptic vesicle transport.
1903744	positive regulation of anterograde synaptic vesicle transport	P	Any process that activates or increases the frequency, rate or extent of anterograde synaptic vesicle transport.
1903745	negative regulation of pharyngeal pumping	P	Any process that stops, prevents or reduces the frequency, rate or extent of pharyngeal pumping.
1903746	positive regulation of pharyngeal pumping	P	Any process that activates or increases the frequency, rate or extent of pharyngeal pumping.
1903747	regulation of establishment of protein localization to mitochondrion	P	Any process that modulates the frequency, rate or extent of establishment of protein localization to mitochondrion.
1903748	negative regulation of establishment of protein localization to mitochondrion	P	Any process that stops, prevents or reduces the frequency, rate or extent of establishment of protein localization to mitochondrion.
1903749	positive regulation of establishment of protein localization to mitochondrion	P	Any process that activates or increases the frequency, rate or extent of establishment of protein localization to mitochondrion.
1903750	regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide	P	Any process that modulates the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to hydrogen peroxide.
1903751	negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide	P	Any process that stops, prevents or reduces the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to hydrogen peroxide.
1903752	positive regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide	P	Any process that activates or increases the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to hydrogen peroxide.
1903753	negative regulation of p38MAPK cascade	P	Any process that stops, prevents or reduces the frequency, rate or extent of p38MAPK cascade.
1903754	cortical microtubule plus-end	C	The plus-end of a cortical microtubule.
1903755	positive regulation of SUMO transferase activity	P	Any process that activates or increases the frequency, rate or extent of SUMO transferase activity.
1903756	regulation of transcription from RNA polymerase II promoter by histone modification	P	A histone modification that results in regulation of transcription from RNA polymerase II promoter.
1903757	positive regulation of transcription from RNA polymerase II promoter by histone modification	P	A histone modification that results in positive regulation of transcription from RNA polymerase II promoter.
1903758	negative regulation of transcription from RNA polymerase II promoter by histone modification	P	A histone modification that results in negative regulation of transcription from RNA polymerase II promoter.
1903759	signal transduction involved in regulation of aerobic respiration	P	Any signal transduction that is involved in regulation of aerobic respiration.
1903760	regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization	P	Any process that modulates the frequency, rate or extent of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization.
1903761	negative regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization	P	Any process that stops, prevents or reduces the frequency, rate or extent of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization.
1903762	positive regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization	P	Any process that activates or increases the frequency, rate or extent of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization.
1903763	gap junction channel activity involved in cell communication by electrical coupling	F	Any gap junction channel activity that is involved in cell communication by electrical coupling.
1903764	regulation of potassium ion export across plasma membrane	P	Any process that modulates the frequency, rate or extent of potassium ion export across plasma membrane.
1903765	negative regulation of potassium ion export across plasma membrane	P	Any process that stops, prevents or reduces the frequency, rate or extent of potassium ion export across plasma membrane.
1903766	positive regulation of potassium ion export across plasma membrane	P	Any process that activates or increases the frequency, rate or extent of potassium ion export across plasma membrane.
1903767	sweet taste receptor complex	C	A protein complex which is capable of sweet taste receptor activity.
1903768	taste receptor complex	C	A protein complex which is capable of taste receptor activity.
1903769	negative regulation of cell proliferation in bone marrow	P	Any process that stops, prevents or reduces the frequency, rate or extent of cell proliferation in bone marrow.
1903770	negative regulation of beta-galactosidase activity	P	Any process that stops, prevents or reduces the frequency, rate or extent of beta-galactosidase activity.
1903771	positive regulation of beta-galactosidase activity	P	Any process that activates or increases the frequency, rate or extent of beta-galactosidase activity.
1903772	regulation of viral budding via host ESCRT complex	P	Any process that modulates the frequency, rate or extent of viral budding via host ESCRT complex.
1903773	negative regulation of viral budding via host ESCRT complex	P	Any process that stops, prevents or reduces the frequency, rate or extent of viral budding via host ESCRT complex.
1903774	positive regulation of viral budding via host ESCRT complex	P	Any process that activates or increases the frequency, rate or extent of viral budding via host ESCRT complex.
1903775	regulation of DNA double-strand break processing	P	Any process that modulates the frequency, rate or extent of DNA double-strand break processing.
1903776	regulation of double-strand break repair via single-strand annealing, removal of nonhomologous ends	P	Any process that modulates the frequency, rate or extent of double-strand break repair via single-strand annealing, removal of nonhomologous ends.
1903777	melibiose binding	F	Interacting selectively and non-covalently with melibiose.
1903778	protein localization to vacuolar membrane	P	A process in which a protein is transported to, or maintained in, a location within a vacuolar membrane.
1903779	regulation of cardiac conduction	P	Any process that modulates the frequency, rate or extent of cardiac conduction.
1903780	negative regulation of cardiac conduction	P	Any process that stops, prevents or reduces the frequency, rate or extent of cardiac conduction.
1903781	positive regulation of cardiac conduction	P	Any process that activates or increases the frequency, rate or extent of cardiac conduction.
1903782	regulation of sodium ion import across plasma membrane	P	Any process that modulates the frequency, rate or extent of sodium ion import across plasma membrane.
1903783	negative regulation of sodium ion import across plasma membrane	P	Any process that stops, prevents or reduces the frequency, rate or extent of sodium ion import across plasma membrane.
1903784	positive regulation of sodium ion import across plasma membrane	P	Any process that activates or increases the frequency, rate or extent of sodium ion import across plasma membrane.
1903785	L-valine transmembrane transport	P	The directed movement of L-valine across a membrane.
1903786	regulation of glutathione biosynthetic process	P	Any process that modulates the frequency, rate or extent of glutathione biosynthetic process.
1903787	negative regulation of glutathione biosynthetic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of glutathione biosynthetic process.
1903788	positive regulation of glutathione biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of glutathione biosynthetic process.
1903789	regulation of amino acid transmembrane transport	P	Any process that modulates the frequency, rate or extent of amino acid transmembrane transport.
1903790	guanine nucleotide transmembrane transport	P	The directed movement of guanyl nucleotide across a membrane.
1903791	uracil transmembrane transport	P	The directed movement of uracil across a membrane.
1903792	negative regulation of anion transport	P	Any process that stops, prevents or reduces the frequency, rate or extent of anion transport.
1903793	positive regulation of anion transport	P	Any process that activates or increases the frequency, rate or extent of anion transport.
1903794	cortisol binding	F	Interacting selectively and non-covalently with cortisol.
1903795	regulation of inorganic anion transmembrane transport	P	Any process that modulates the frequency, rate or extent of inorganic anion transmembrane transport.
1903796	negative regulation of inorganic anion transmembrane transport	P	Any process that stops, prevents or reduces the frequency, rate or extent of inorganic anion transmembrane transport.
1903797	positive regulation of inorganic anion transmembrane transport	P	Any process that activates or increases the frequency, rate or extent of inorganic anion transmembrane transport.
1903798	regulation of production of miRNAs involved in gene silencing by miRNA	P	Any process that modulates the frequency, rate or extent of production of miRNAs involved in gene silencing by miRNA.
1903799	negative regulation of production of miRNAs involved in gene silencing by miRNA	P	Any process that stops, prevents or reduces the frequency, rate or extent of production of miRNAs involved in gene silencing by miRNA.
1903800	positive regulation of production of miRNAs involved in gene silencing by miRNA	P	Any process that activates or increases the frequency, rate or extent of production of miRNAs involved in gene silencing by miRNA.
1903801	L-leucine import into cell	P	The directed movement of L-leucine into a cell.
1903802	L-glutamate(1-) import into cell	P	The directed movement of L-glutamate(1-) into a cell.
1903803	L-glutamine import into cell	P	The directed movement of L-glutamine into a cell.
1903804	glycine import into cell	P	The directed movement of glycine into a cell.
1903805	L-valine import into cell	P	The directed movement of L-valine into a cell.
1903806	L-isoleucine import into cell	P	The directed movement of L-isoleucine into a cell.
1903807	L-threonine import into cell	P	The directed movement of L-threonine into a cell.
1903808	L-tyrosine import into cell	P	The directed movement of L-tyrosine into a cell.
1903809	L-proline import into cell	P	The directed movement of L-proline into a cell.
1903810	L-histidine import into cell	P	The directed movement of L-histidine into a cell.
1903811	L-asparagine import into cell	P	The directed movement of L-asparagine into a cell.
1903812	L-serine import into cell	P	The directed movement of L-serine into a cell.
1903813	L-methionine import into cell	P	The directed movement of L-methionine into a cell.
1903814	regulation of collecting lymphatic vessel constriction	P	Any process that modulates the frequency, rate or extent of collecting lymphatic vessel constriction.
1903815	negative regulation of collecting lymphatic vessel constriction	P	Any process that stops, prevents or reduces the frequency, rate or extent of collecting lymphatic vessel constriction.
1903816	positive regulation of collecting lymphatic vessel constriction	P	Any process that activates or increases the frequency, rate or extent of collecting lymphatic vessel constriction.
1903817	negative regulation of voltage-gated potassium channel activity	P	Any process that stops, prevents or reduces the frequency, rate or extent of voltage-gated potassium channel activity.
1903818	positive regulation of voltage-gated potassium channel activity	P	Any process that activates or increases the frequency, rate or extent of voltage-gated potassium channel activity.
1903819	detection of stimulus involved in mitotic cytokinesis checkpoint	P	Any detection of stimulus that is involved in a mitotic cytokinesis checkpoint.
1903820	signal transduction involved in mitotic cytokinesis checkpoint	P	Any signal transduction that is involved in a mitotic cytokinesis checkpoint.
1903821	detection of stimulus involved in morphogenesis checkpoint	P	Any detection of stimulus that is involved in morphogenesis checkpoint.
1903822	signal transduction involved in morphogenesis checkpoint	P	Any signal transduction that is involved in morphogenesis checkpoint.
1903823	telomere single strand break repair	P	Single strand break repair that takes place in a telomere.
1903824	negative regulation of telomere single strand break repair	P	Any process that stops, prevents or reduces the frequency, rate or extent of telomere single strand break repair.
1903825	organic acid transmembrane transport	P	The directed movement of organic acid across a membrane.
1903826	arginine transmembrane transport	P	The directed movement of arginine across a membrane.
1903827	regulation of cellular protein localization	P	Any process that modulates the frequency, rate or extent of cellular protein localization. Cellular protein localization is any process in which a protein is transported to, and/or maintained in, a specific location and encompasses movement within the cell, from within the cell to the cell surface, or from one location to another at the surface of a cell.
1903828	negative regulation of cellular protein localization	P	Any process that stops, prevents or reduces the frequency, rate or extent of cellular protein localization. Cellular protein localization is any process in which a protein is transported to, and/or maintained in, a specific location and encompasses movement within the cell, from within the cell to the cell surface, or from one location to another at the surface of a cell.
1903829	positive regulation of cellular protein localization	P	Any process that activates or increases the frequency, rate or extent of cellular protein localization. Cellular protein localization is any process in which a protein is transported to, and/or maintained in, a specific location and encompasses movement within the cell, from within the cell to the cell surface, or from one location to another at the surface of a cell.
1903830	magnesium ion transmembrane transport	P	The directed movement of magnesium ion across a membrane.
1903831	signal transduction involved in cellular response to ammonium ion	P	Any signal transduction that is involved in cellular response to ammonium ion.
1903832	regulation of cellular response to amino acid starvation	P	Any process that modulates the frequency, rate or extent of cellular response to amino acid starvation.
1903833	positive regulation of cellular response to amino acid starvation	P	Any process that activates or increases the frequency, rate or extent of cellular response to amino acid starvation.
1903837	regulation of mRNA 3'-UTR binding	P	Any process that modulates the frequency, rate or extent of mRNA 3'-UTR binding.
1903838	negative regulation of mRNA 3'-UTR binding	P	Any process that stops, prevents or reduces the frequency, rate or extent of mRNA 3'-UTR binding.
1903839	positive regulation of mRNA 3'-UTR binding	P	Any process that activates or increases the frequency, rate or extent of mRNA 3'-UTR binding.
1903840	response to arsenite(3-)	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an arsenite(3-) stimulus.
1903841	cellular response to arsenite(3-)	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an arsenite(3-) stimulus.
1903842	response to arsenite ion	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an arsenite ion stimulus.
1903843	cellular response to arsenite ion	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an arsenite ion stimulus.
1903844	regulation of cellular response to transforming growth factor beta stimulus	P	Any process that modulates the frequency, rate or extent of cellular response to transforming growth factor beta stimulus.
1903845	negative regulation of cellular response to transforming growth factor beta stimulus	P	Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to transforming growth factor beta stimulus.
1903846	positive regulation of cellular response to transforming growth factor beta stimulus	P	Any process that activates or increases the frequency, rate or extent of cellular response to transforming growth factor beta stimulus.
1903847	regulation of aorta morphogenesis	P	Any process that modulates the frequency, rate or extent of aorta morphogenesis.
1903848	negative regulation of aorta morphogenesis	P	Any process that stops, prevents or reduces the frequency, rate or extent of aorta morphogenesis.
1903849	positive regulation of aorta morphogenesis	P	Any process that activates or increases the frequency, rate or extent of aorta morphogenesis.
1903850	regulation of cristae formation	P	Any process that modulates the frequency, rate or extent of cristae formation.
1903851	negative regulation of cristae formation	P	Any process that stops, prevents or reduces the frequency, rate or extent of cristae formation.
1903852	positive regulation of cristae formation	P	Any process that activates or increases the frequency, rate or extent of cristae formation.
1903853	regulation of stress response to copper ion	P	Any process that modulates the frequency, rate or extent of stress response to copper ion.
1903854	negative regulation of stress response to copper ion	P	Any process that stops, prevents or reduces the frequency, rate or extent of stress response to copper ion.
1903855	positive regulation of stress response to copper ion	P	Any process that activates or increases the frequency, rate or extent of stress response to copper ion.
1903856	regulation of cytokinin dehydrogenase activity	P	Any process that modulates the frequency, rate or extent of cytokinin dehydrogenase activity.
1903857	negative regulation of cytokinin dehydrogenase activity	P	Any process that stops, prevents or reduces the frequency, rate or extent of cytokinin dehydrogenase activity.
1903858	protein localization to old growing cell tip	P	A process in which a protein is transported to, or maintained in, a location within an old growing cell tip.
1903859	regulation of dendrite extension	P	Any process that modulates the frequency, rate or extent of dendrite extension.
1903860	negative regulation of dendrite extension	P	Any process that stops, prevents or reduces the frequency, rate or extent of dendrite extension.
1903861	positive regulation of dendrite extension	P	Any process that activates or increases the frequency, rate or extent of dendrite extension.
1903862	positive regulation of oxidative phosphorylation	P	Any process that activates or increases the frequency, rate or extent of oxidative phosphorylation.
1903863	P granule assembly	P	The aggregation, arrangement and bonding together of a set of components to form a P granule.
1903864	P granule disassembly	P	The disaggregation of a P granule into its constituent components.
1903865	sigma factor antagonist complex	C	A protein complex which is capable of sigma factor antagonist activity.
1903866	palisade mesophyll development	P	The process whose specific outcome is the progression of a palisade mesophyll over time, from its formation to the mature structure.
1903867	extraembryonic membrane development	P	The process whose specific outcome is the progression of an extraembryonic membrane over time, from its formation to the mature structure.
1903868	regulation of methylenetetrahydrofolate reductase (NAD(P)H) activity	P	Any process that modulates the frequency, rate or extent of methylenetetrahydrofolate reductase (NAD(P)H) activity.
1903869	negative regulation of methylenetetrahydrofolate reductase (NAD(P)H) activity	P	Any process that stops, prevents or reduces the frequency, rate or extent of methylenetetrahydrofolate reductase (NAD(P)H) activity.
1903870	positive regulation of methylenetetrahydrofolate reductase (NAD(P)H) activity	P	Any process that activates or increases the frequency, rate or extent of methylenetetrahydrofolate reductase (NAD(P)H) activity.
1903871	DNA recombinase mediator complex assembly	P	The aggregation, arrangement and bonding together of a set of components to form a DNA recombinase mediator complex.
1903872	regulation of DNA recombinase mediator complex assembly	P	Any process that modulates the frequency, rate or extent of DNA recombinase mediator complex assembly.
1903873	negative regulation of DNA recombinase mediator complex assembly	P	Any process that stops, prevents or reduces the frequency, rate or extent of DNA recombinase mediator complex assembly.
1903874	ferrous iron transmembrane transport	P	The directed movement of ferrous iron (iron(2+)) across a membrane.
1903875	corticosterone binding	F	Interacting selectively and non-covalently with corticosterone.
1903876	11-deoxycortisol binding	F	Interacting selectively and non-covalently with 11-deoxycortisol.
1903877	21-deoxycortisol binding	F	Interacting selectively and non-covalently with 21-deoxycortisol.
1903878	11-deoxycorticosterone binding	F	Interacting selectively and non-covalently with 11-deoxycorticosterone.
1903879	11beta-hydroxyprogesterone binding	F	Interacting selectively and non-covalently with 11beta-hydroxyprogesterone.
1903880	17alpha-hydroxyprogesterone binding	F	Interacting selectively and non-covalently with 17alpha-hydroxyprogesterone.
1903881	regulation of interleukin-17-mediated signaling pathway	P	Any process that modulates the frequency, rate or extent of interleukin-17-mediated signaling pathway.
1903882	negative regulation of interleukin-17-mediated signaling pathway	P	Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-17-mediated signaling pathway.
1903883	positive regulation of interleukin-17-mediated signaling pathway	P	Any process that activates or increases the frequency, rate or extent of interleukin-17-mediated signaling pathway.
1903884	regulation of chemokine (C-C motif) ligand 20 production	P	Any process that modulates the frequency, rate or extent of chemokine (C-C motif) ligand 20 production.
1903885	negative regulation of chemokine (C-C motif) ligand 20 production	P	Any process that stops, prevents or reduces the frequency, rate or extent of chemokine (C-C motif) ligand 20 production.
1903886	positive regulation of chemokine (C-C motif) ligand 20 production	P	Any process that activates or increases the frequency, rate or extent of chemokine (C-C motif) ligand 20 production.
1903888	regulation of plant epidermal cell differentiation	P	Any process that modulates the frequency, rate or extent of plant epidermal cell differentiation.
1903889	negative regulation of plant epidermal cell differentiation	P	Any process that stops, prevents or reduces the frequency, rate or extent of plant epidermal cell differentiation.
1903890	positive regulation of plant epidermal cell differentiation	P	Any process that activates or increases the frequency, rate or extent of plant epidermal cell differentiation.
1903891	regulation of ATF6-mediated unfolded protein response	P	Any process that modulates the frequency, rate or extent of the ATF6-mediated unfolded protein response.
1903892	negative regulation of ATF6-mediated unfolded protein response	P	Any process that stops, prevents or reduces the frequency, rate or extent of the ATF6-mediated unfolded protein response.
1903893	positive regulation of ATF6-mediated unfolded protein response	P	Any process that activates or increases the frequency, rate or extent of the ATF6-mediated unfolded protein response.
1903894	regulation of IRE1-mediated unfolded protein response	P	Any process that modulates the frequency, rate or extent of the IRE1-mediated unfolded protein response.
1903895	negative regulation of IRE1-mediated unfolded protein response	P	Any process that stops, prevents or reduces the frequency, rate or extent of the IRE1-mediated unfolded protein response.
1903896	positive regulation of IRE1-mediated unfolded protein response	P	Any process that activates or increases the frequency, rate or extent of the IRE1-mediated unfolded protein response.
1903897	regulation of PERK-mediated unfolded protein response	P	Any process that modulates the frequency, rate or extent of the PERK-mediated unfolded protein response.
1903898	negative regulation of PERK-mediated unfolded protein response	P	Any process that stops, prevents or reduces the frequency, rate or extent of the PERK-mediated unfolded protein response.
1903899	positive regulation of PERK-mediated unfolded protein response	P	Any process that activates or increases the frequency, rate or extent of the PERK-mediated unfolded protein response.
1903900	regulation of viral life cycle	P	Any process that modulates the frequency, rate or extent of viral life cycle.
1903901	negative regulation of viral life cycle	P	Any process that stops, prevents or reduces the frequency, rate or extent of viral life cycle.
1903902	positive regulation of viral life cycle	P	Any process that activates or increases the frequency, rate or extent of viral life cycle.
1903903	regulation of establishment of T cell polarity	P	Any process that modulates the frequency, rate or extent of establishment of T cell polarity.
1903904	negative regulation of establishment of T cell polarity	P	Any process that stops, prevents or reduces the frequency, rate or extent of establishment of T cell polarity.
1903905	positive regulation of establishment of T cell polarity	P	Any process that activates or increases the frequency, rate or extent of establishment of T cell polarity.
1903906	regulation of plasma membrane raft polarization	P	Any process that modulates the frequency, rate or extent of plasma membrane raft polarization.
1903907	negative regulation of plasma membrane raft polarization	P	Any process that stops, prevents or reduces the frequency, rate or extent of plasma membrane raft polarization.
1903908	positive regulation of plasma membrane raft polarization	P	Any process that activates or increases the frequency, rate or extent of plasma membrane raft polarization.
1903909	regulation of receptor clustering	P	Any process that modulates the frequency, rate or extent of receptor clustering.
1903910	negative regulation of receptor clustering	P	Any process that stops, prevents or reduces the frequency, rate or extent of receptor clustering.
1903911	positive regulation of receptor clustering	P	Any process that activates or increases the frequency, rate or extent of receptor clustering.
1903912	negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation	P	Any process that stops, prevents or reduces the frequency, rate or extent of endoplasmic reticulum stress-induced eiF2alpha phosphorylation.
1903913	regulation of fusion of virus membrane with host plasma membrane	P	Any process that modulates the frequency, rate or extent of fusion of virus membrane with host plasma membrane.
1903914	negative regulation of fusion of virus membrane with host plasma membrane	P	Any process that stops, prevents or reduces the frequency, rate or extent of fusion of virus membrane with host plasma membrane.
1903915	positive regulation of fusion of virus membrane with host plasma membrane	P	Any process that activates or increases the frequency, rate or extent of fusion of virus membrane with host plasma membrane.
1903916	regulation of endoplasmic reticulum stress-induced eIF2 alpha dephosphorylation	P	Any process that modulates the frequency, rate or extent of endoplasmic reticulum stress-induced eIF2alpha dephosphorylation.
1903917	positive regulation of endoplasmic reticulum stress-induced eIF2 alpha dephosphorylation	P	Any process that activates or increases the frequency, rate or extent of endoplasmic reticulum stress-induced eIF2alpha dephosphorylation.
1903918	regulation of actin filament severing	P	Any process that modulates the frequency, rate or extent of actin filament severing.
1903919	negative regulation of actin filament severing	P	Any process that stops, prevents or reduces the frequency, rate or extent of actin filament severing.
1903920	positive regulation of actin filament severing	P	Any process that activates or increases the frequency, rate or extent of actin filament severing.
1903921	regulation of protein processing in phagocytic vesicle	P	Any process that modulates the frequency, rate or extent of protein processing in phagocytic vesicle.
1903922	negative regulation of protein processing in phagocytic vesicle	P	Any process that stops, prevents or reduces the frequency, rate or extent of protein processing in phagocytic vesicle.
1903923	positive regulation of protein processing in phagocytic vesicle	P	Any process that activates or increases the frequency, rate or extent of protein processing in phagocytic vesicle.
1903924	estradiol binding	F	Interacting selectively and non-covalently with estradiol.
1903925	response to bisphenol A	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bisphenol A stimulus.
1903926	cellular response to bisphenol A	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bisphenol A stimulus.
1903927	response to cyanide	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cyanide stimulus.
1903928	cellular response to cyanide	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cyanide stimulus.
1903929	primary palate development	P	The process whose specific outcome is the progression of a primary palate over time, from its formation to the mature structure.
1903930	regulation of pyrimidine-containing compound salvage	P	Any process that modulates the frequency, rate or extent of pyrimidine-containing compound salvage.
1903931	positive regulation of pyrimidine-containing compound salvage	P	Any process that activates or increases the frequency, rate or extent of pyrimidine-containing compound salvage.
1903932	regulation of DNA primase activity	P	Any process that modulates the frequency, rate or extent of DNA primase activity.
1903933	negative regulation of DNA primase activity	P	Any process that stops, prevents or reduces the frequency, rate or extent of DNA primase activity.
1903934	positive regulation of DNA primase activity	P	Any process that activates or increases the frequency, rate or extent of DNA primase activity.
1903935	response to sodium arsenite	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sodium arsenite stimulus.
1903936	cellular response to sodium arsenite	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sodium arsenite stimulus.
1903937	response to acrylamide	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acrylamide stimulus.
1903938	cellular response to acrylamide	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acrylamide stimulus.
1903939	regulation of TORC2 signaling	P	Any process that modulates the frequency, rate or extent of TORC2 signaling.
1903940	negative regulation of TORC2 signaling	P	Any process that stops, prevents or reduces the frequency, rate or extent of TORC2 signaling.
1903941	negative regulation of respiratory gaseous exchange	P	Any process that stops, prevents or reduces the frequency, rate or extent of respiratory gaseous exchange.
1903942	positive regulation of respiratory gaseous exchange	P	Any process that activates or increases the frequency, rate or extent of respiratory gaseous exchange.
1903943	regulation of hepatocyte apoptotic process	P	Any process that modulates the frequency, rate or extent of hepatocyte apoptotic process.
1903944	negative regulation of hepatocyte apoptotic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of hepatocyte apoptotic process.
1903945	positive regulation of hepatocyte apoptotic process	P	Any process that activates or increases the frequency, rate or extent of hepatocyte apoptotic process.
1903946	negative regulation of ventricular cardiac muscle cell action potential	P	Any process that stops, prevents or reduces the frequency, rate or extent of ventricular cardiac muscle cell action potential.
1903947	positive regulation of ventricular cardiac muscle cell action potential	P	Any process that activates or increases the frequency, rate or extent of ventricular cardiac muscle cell action potential.
1903948	negative regulation of atrial cardiac muscle cell action potential	P	Any process that stops, prevents or reduces the frequency, rate or extent of atrial cardiac muscle cell action potential.
1903949	positive regulation of atrial cardiac muscle cell action potential	P	Any process that activates or increases the frequency, rate or extent of atrial cardiac muscle cell action potential.
1903950	negative regulation of AV node cell action potential	P	Any process that stops, prevents or reduces the frequency, rate or extent of AV node cell action potential.
1903951	positive regulation of AV node cell action potential	P	Any process that activates or increases the frequency, rate or extent of AV node cell action potential.
1903952	regulation of voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization	P	Any process that modulates the frequency, rate or extent of voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization.
1903953	negative regulation of voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization	P	Any process that stops, prevents or reduces the frequency, rate or extent of voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization.
1903954	positive regulation of voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization	P	Any process that activates or increases the frequency, rate or extent of voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization.
1903955	positive regulation of protein targeting to mitochondrion	P	Any process that activates or increases the frequency, rate or extent of protein targeting to mitochondrion.
1903956	response to latrunculin B	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a latrunculin B stimulus.
1903957	cellular response to latrunculin B	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a latrunculin B stimulus.
1903958	nitric-oxide synthase complex	C	A protein complex which is capable of nitric-oxide synthase activity.
1903959	regulation of anion transmembrane transport	P	Any process that modulates the frequency, rate or extent of anion transmembrane transport.
1903960	negative regulation of anion transmembrane transport	P	Any process that stops, prevents or reduces the frequency, rate or extent of anion transmembrane transport.
1903961	positive regulation of anion transmembrane transport	P	Any process that activates or increases the frequency, rate or extent of anion transmembrane transport.
1903962	arachidonate transporter activity	F	Enables the directed movement of arachidonate into, out of or within a cell, or between cells.
1903963	arachidonate transport	P	The directed movement of an arachidonate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
1903964	monounsaturated fatty acid metabolic process	P	The chemical reactions and pathways involving monounsaturated fatty acid.
1903965	monounsaturated fatty acid catabolic process	P	The chemical reactions and pathways resulting in the breakdown of monounsaturated fatty acid.
1903966	monounsaturated fatty acid biosynthetic process	P	The chemical reactions and pathways resulting in the formation of monounsaturated fatty acid.
1903967	response to micafungin	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a micafungin stimulus.
1903968	cellular response to micafungin	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a micafungin stimulus.
1903969	regulation of response to macrophage colony-stimulating factor	P	Any process that modulates the frequency, rate or extent of response to macrophage colony-stimulating factor.
1903970	negative regulation of response to macrophage colony-stimulating factor	P	Any process that stops, prevents or reduces the frequency, rate or extent of response to macrophage colony-stimulating factor.
1903971	positive regulation of response to macrophage colony-stimulating factor	P	Any process that activates or increases the frequency, rate or extent of response to macrophage colony-stimulating factor.
1903972	regulation of cellular response to macrophage colony-stimulating factor stimulus	P	Any process that modulates the frequency, rate or extent of cellular response to macrophage colony-stimulating factor stimulus.
1903973	negative regulation of cellular response to macrophage colony-stimulating factor stimulus	P	Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to macrophage colony-stimulating factor stimulus.
1903974	positive regulation of cellular response to macrophage colony-stimulating factor stimulus	P	Any process that activates or increases the frequency, rate or extent of cellular response to macrophage colony-stimulating factor stimulus.
1903975	regulation of glial cell migration	P	Any process that modulates the frequency, rate or extent of glial cell migration.
1903976	negative regulation of glial cell migration	P	Any process that stops, prevents or reduces the frequency, rate or extent of glial cell migration.
1903977	positive regulation of glial cell migration	P	Any process that activates or increases the frequency, rate or extent of glial cell migration.
1903978	regulation of microglial cell activation	P	Any process that modulates the frequency, rate or extent of microglial cell activation.
1903979	negative regulation of microglial cell activation	P	Any process that stops, prevents or reduces the frequency, rate or extent of microglial cell activation.
1903980	positive regulation of microglial cell activation	P	Any process that activates or increases the frequency, rate or extent of microglial cell activation.
1903981	enterobactin binding	F	Interacting selectively and non-covalently with enterobactin.
1903982	negative regulation of microvillus length	P	A process that decreases the length of a microvillus.
1903983	positive regulation of microvillus length	P	A process that increases the length of a microvillus.
1903984	positive regulation of TRAIL-activated apoptotic signaling pathway	P	Any process that activates or increases the frequency, rate or extent of TRAIL-activated apoptotic signaling pathway.
1903985	regulation of intestinal D-glucose absorption	P	Any process that modulates the frequency, rate or extent of intestinal D-glucose absorption.
1903988	ferrous iron export	P	The directed movement of iron(2+) out of a cell or organelle.
1903989	regulation of ferrous iron import into cell	P	Any process that modulates the frequency, rate or extent of ferrous iron import into cell.
1903990	negative regulation of ferrous iron import into cell	P	Any process that stops, prevents or reduces the frequency, rate or extent of ferrous iron import into cell.
1903991	positive regulation of ferrous iron import into cell	P	Any process that activates or increases the frequency, rate or extent of ferrous iron import into cell.
1903995	regulation of non-membrane spanning protein tyrosine kinase activity	P	Any process that modulates the frequency, rate or extent of non-membrane spanning protein tyrosine kinase activity.
1903996	negative regulation of non-membrane spanning protein tyrosine kinase activity	P	Any process that stops, prevents or reduces the frequency, rate or extent of non-membrane spanning protein tyrosine kinase activity.
1903997	positive regulation of non-membrane spanning protein tyrosine kinase activity	P	Any process that activates or increases the frequency, rate or extent of non-membrane spanning protein tyrosine kinase activity.
1903998	regulation of eating behavior	P	Any process that modulates the frequency, rate or extent of eating behavior.
1903999	negative regulation of eating behavior	P	Any process that stops, prevents or reduces the frequency, rate or extent of eating behavior.
1904000	positive regulation of eating behavior	P	Any process that activates or increases the frequency, rate or extent of eating behavior.
1904001	positive regulation of pyrimidine-containing compound salvage by positive regulation of transcription from RNA polymerase II promoter	P	A positive regulation of transcription from RNA polymerase II promoter that results in positive regulation of pyrimidine-containing compound salvage.
1904002	regulation of sebum secreting cell proliferation	P	Any process that modulates the frequency, rate or extent of sebum secreting cell proliferation.
1904003	negative regulation of sebum secreting cell proliferation	P	Any process that stops, prevents or reduces the frequency, rate or extent of sebum secreting cell proliferation.
1904004	positive regulation of sebum secreting cell proliferation	P	Any process that activates or increases the frequency, rate or extent of sebum secreting cell proliferation.
1904005	regulation of phospholipase D activity	P	Any process that modulates the frequency, rate or extent of phospholipase D activity.
1904006	negative regulation of phospholipase D activity	P	Any process that stops, prevents or reduces the frequency, rate or extent of phospholipase D activity.
1904007	positive regulation of phospholipase D activity	P	Any process that activates or increases the frequency, rate or extent of phospholipase D activity.
1904008	response to monosodium glutamate	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a monosodium glutamate stimulus.
1904009	cellular response to monosodium glutamate	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a monosodium glutamate stimulus.
1904010	response to Aroclor 1254	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an Aroclor 1254 stimulus.
1904011	cellular response to Aroclor 1254	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an Aroclor 1254 stimulus.
1904012	platinum binding	F	Interacting selectively and non-covalently with platinum.
1904013	xenon atom binding	F	Interacting selectively and non-covalently with xenon atom.
1904014	response to serotonin	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a serotonin stimulus.
1904015	cellular response to serotonin	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a serotonin stimulus.
1904016	response to Thyroglobulin triiodothyronine	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a Thyroglobulin triiodothyronine stimulus.
1904017	cellular response to Thyroglobulin triiodothyronine	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a Thyroglobulin triiodothyronine stimulus.
1904018	positive regulation of vasculature development	P	Any process that activates or increases the frequency, rate or extent of vasculature development.
1904019	epithelial cell apoptotic process	P	Any apoptotic process in an epithelial cell.
1904020	regulation of G-protein coupled receptor internalization	P	Any process that modulates the frequency, rate or extent of G-protein coupled receptor internalization.
1904021	negative regulation of G-protein coupled receptor internalization	P	Any process that stops, prevents or reduces the frequency, rate or extent of G-protein coupled receptor internalization.
1904022	positive regulation of G-protein coupled receptor internalization	P	Any process that activates or increases the frequency, rate or extent of G-protein coupled receptor internalization.
1904023	regulation of glucose catabolic process to lactate via pyruvate	P	Any process that modulates the frequency, rate or extent of glucose catabolic process to lactate via pyruvate.
1904024	negative regulation of glucose catabolic process to lactate via pyruvate	P	Any process that stops, prevents or reduces the frequency, rate or extent of glucose catabolic process to lactate via pyruvate.
1904025	positive regulation of glucose catabolic process to lactate via pyruvate	P	Any process that activates or increases the frequency, rate or extent of glucose catabolic process to lactate via pyruvate.
1904026	regulation of collagen fibril organization	P	Any process that modulates the frequency, rate or extent of collagen fibril organization.
1904027	negative regulation of collagen fibril organization	P	Any process that stops, prevents or reduces the frequency, rate or extent of collagen fibril organization.
1904028	positive regulation of collagen fibril organization	P	Any process that activates or increases the frequency, rate or extent of collagen fibril organization.
1904029	regulation of cyclin-dependent protein kinase activity	P	Any process that modulates the frequency, rate or extent of cyclin-dependent protein kinase activity.
1904030	negative regulation of cyclin-dependent protein kinase activity	P	Any process that stops, prevents or reduces the frequency, rate or extent of cyclin-dependent protein kinase activity.
1904031	positive regulation of cyclin-dependent protein kinase activity	P	Any process that activates or increases the frequency, rate or extent of cyclin-dependent protein kinase activity.
1904032	regulation of t-SNARE clustering	P	Any process that modulates the frequency, rate or extent of t-SNARE clustering.
1904033	negative regulation of t-SNARE clustering	P	Any process that stops, prevents or reduces the frequency, rate or extent of t-SNARE clustering.
1904034	positive regulation of t-SNARE clustering	P	Any process that activates or increases the frequency, rate or extent of t-SNARE clustering.
1904035	regulation of epithelial cell apoptotic process	P	Any process that modulates the frequency, rate or extent of epithelial cell apoptotic process.
1904036	negative regulation of epithelial cell apoptotic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of epithelial cell apoptotic process.
1904037	positive regulation of epithelial cell apoptotic process	P	Any process that activates or increases the frequency, rate or extent of epithelial cell apoptotic process.
1904038	regulation of ferrous iron export	P	Any process that modulates the frequency, rate or extent of iron(2+) export.
1904039	negative regulation of ferrous iron export	P	Any process that stops, prevents or reduces the frequency, rate or extent of iron(2+) export.
1904040	positive regulation of ferrous iron export	P	Any process that activates or increases the frequency, rate or extent of iron(2+) export.
1904041	regulation of cystathionine beta-synthase activity	P	Any process that modulates the frequency, rate or extent of cystathionine beta-synthase activity.
1904042	negative regulation of cystathionine beta-synthase activity	P	Any process that stops, prevents or reduces the frequency, rate or extent of cystathionine beta-synthase activity.
1904043	positive regulation of cystathionine beta-synthase activity	P	Any process that activates or increases the frequency, rate or extent of cystathionine beta-synthase activity.
1904044	response to aldosterone	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an aldosterone stimulus.
1904045	cellular response to aldosterone	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an aldosterone stimulus.
1904046	negative regulation of vascular endothelial growth factor production	P	Any process that stops, prevents or reduces the frequency, rate or extent of vascular endothelial growth factor production.
1904047	S-adenosyl-L-methionine binding	F	Interacting selectively and non-covalently with S-adenosyl-L-methionine.
1904048	regulation of spontaneous neurotransmitter secretion	P	Any process that modulates the frequency, rate or extent of spontaneous neurotransmitter secretion.
1904049	negative regulation of spontaneous neurotransmitter secretion	P	Any process that stops, prevents or reduces the frequency, rate or extent of spontaneous neurotransmitter secretion.
1904050	positive regulation of spontaneous neurotransmitter secretion	P	Any process that activates or increases the frequency, rate or extent of spontaneous neurotransmitter secretion.
1904051	regulation of protein targeting to vacuole involved in autophagy	P	Any process that modulates the frequency, rate or extent of protein targeting to vacuole involved in autophagy.
1904052	negative regulation of protein targeting to vacuole involved in autophagy	P	Any process that stops, prevents or reduces the frequency, rate or extent of protein targeting to vacuole involved in autophagy.
1904053	positive regulation of protein targeting to vacuole involved in autophagy	P	Any process that activates or increases the frequency, rate or extent of protein targeting to vacuole involved in autophagy.
1904054	regulation of cholangiocyte proliferation	P	Any process that modulates the frequency, rate or extent of cholangiocyte proliferation.
1904055	negative regulation of cholangiocyte proliferation	P	Any process that stops, prevents or reduces the frequency, rate or extent of cholangiocyte proliferation.
1904056	positive regulation of cholangiocyte proliferation	P	Any process that activates or increases the frequency, rate or extent of cholangiocyte proliferation.
1904057	negative regulation of sensory perception of pain	P	Any process that stops, prevents or reduces the frequency, rate or extent of sensory perception of pain.
1904058	positive regulation of sensory perception of pain	P	Any process that activates or increases the frequency, rate or extent of sensory perception of pain.
1904059	regulation of locomotor rhythm	P	Any process that modulates the frequency, rate or extent of locomotor rhythm.
1904060	negative regulation of locomotor rhythm	P	Any process that stops, prevents or reduces the frequency, rate or extent of locomotor rhythm.
1904061	positive regulation of locomotor rhythm	P	Any process that activates or increases the frequency, rate or extent of locomotor rhythm.
1904062	regulation of cation transmembrane transport	P	Any process that modulates the frequency, rate or extent of cation transmembrane transport.
1904063	negative regulation of cation transmembrane transport	P	Any process that stops, prevents or reduces the frequency, rate or extent of cation transmembrane transport.
1904064	positive regulation of cation transmembrane transport	P	Any process that activates or increases the frequency, rate or extent of cation transmembrane transport.
1904065	G-protein coupled acetylcholine receptor signaling pathway involved in positive regulation of acetylcholine secretion, neurotransmission	P	Any G-protein coupled acetylcholine receptor signaling pathway that is involved in positive regulation of acetylcholine secretion, neurotransmission.
1904066	G-protein coupled receptor signaling pathway involved in dauer larval development	P	Any G-protein coupled receptor signaling pathway that is involved in dauer larval development.
1904067	ascr#2 binding	F	Interacting selectively and non-covalently with ascr#2.
1904068	G-protein coupled receptor signaling pathway involved in social behavior	P	Any G-protein coupled receptor signaling pathway that is involved in social behavior.
1904069	ascaroside metabolic process	P	The chemical reactions and pathways involving ascaroside.
1904070	ascaroside biosynthetic process	P	The chemical reactions and pathways resulting in the formation of ascaroside.
1904071	presynaptic active zone assembly	P	The aggregation, arrangement and bonding together of a set of components to form a presynaptic active zone. The presynaptic active zone is a specialized region of the plasma membrane and cell cortex of a presynaptic neuron; encompasses a region of the plasma membrane where synaptic vesicles dock and fuse, and a specialized cortical cytoskeletal matrix.
1904072	presynaptic active zone disassembly	P	The disaggregation of a presynaptic active zone into its constituent components.
1904073	regulation of trophectodermal cell proliferation	P	Any process that modulates the frequency, rate or extent of trophectodermal cell proliferation.
1904074	negative regulation of trophectodermal cell proliferation	P	Any process that stops, prevents or reduces the frequency, rate or extent of trophectodermal cell proliferation.
1904075	positive regulation of trophectodermal cell proliferation	P	Any process that activates or increases the frequency, rate or extent of trophectodermal cell proliferation.
1904076	regulation of estrogen biosynthetic process	P	Any process that modulates the frequency, rate or extent of estrogen biosynthetic process.
1904077	negative regulation of estrogen biosynthetic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of estrogen biosynthetic process.
1904078	positive regulation of estrogen biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of estrogen biosynthetic process.
1904080	positive regulation of transcription from RNA polymerase II promoter involved in neuron fate specification	P	Any positive regulation of transcription from RNA polymerase II promoter that is involved in neuron fate specification.
1904081	positive regulation of transcription from RNA polymerase II promoter involved in neuron differentiation	P	Any positive regulation of transcription from RNA polymerase II promoter that is involved in neuron differentiation.
1904082	pyrimidine nucleobase transmembrane transport	P	The directed movement of pyrimidine nucleobase across a membrane.
1904086	regulation of epiboly involved in gastrulation with mouth forming second	P	Any process that modulates the frequency, rate or extent of epiboly involved in gastrulation with mouth forming second.
1904087	negative regulation of epiboly involved in gastrulation with mouth forming second	P	Any process that stops, prevents or reduces the frequency, rate or extent of epiboly involved in gastrulation with mouth forming second.
1904088	positive regulation of epiboly involved in gastrulation with mouth forming second	P	Any process that activates or increases the frequency, rate or extent of epiboly involved in gastrulation with mouth forming second.
1904089	negative regulation of neuron apoptotic process by negative regulation of transcription from RNA polymerase II promoter	P	A negative regulation of transcription from RNA polymerase II promoter that results in negative regulation of neuron apoptotic process.
1904090	peptidase inhibitor complex	C	A protein complex which is capable of peptidase inhibitor activity.
1904091	peptidyl carrier protein activity involved in nonribosomal peptide biosynthesis	F	Any oligopeptide binding that is involved in nonribosomal peptide biosynthetic process.
1904092	regulation of autophagic cell death	P	Any process that modulates the frequency, rate or extent of autophagic cell death.
1904093	negative regulation of autophagic cell death	P	Any process that stops, prevents or reduces the frequency, rate or extent of autophagic cell death.
1904094	positive regulation of autophagic cell death	P	Any process that activates or increases the frequency, rate or extent of autophagic cell death.
1904095	negative regulation of endosperm development	P	Any process that stops, prevents or reduces the frequency, rate or extent of endosperm development.
1904096	protein tyrosine phosphatase complex	C	A protein complex which is capable of protein tyrosine phosphatase activity.
1904097	acid phosphatase complex	C	A protein complex which is capable of acid phosphatase activity.
1904098	regulation of protein O-linked glycosylation	P	Any process that modulates the frequency, rate or extent of protein O-linked glycosylation.
1904099	negative regulation of protein O-linked glycosylation	P	Any process that stops, prevents or reduces the frequency, rate or extent of protein O-linked glycosylation.
1904100	positive regulation of protein O-linked glycosylation	P	Any process that activates or increases the frequency, rate or extent of protein O-linked glycosylation.
1904101	response to acadesine	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acadesine stimulus.
1904102	cellular response to acadesine	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acadesine stimulus.
1904103	regulation of convergent extension involved in gastrulation	P	Any process that modulates the frequency, rate or extent of convergent extension involved in gastrulation.
1904104	negative regulation of convergent extension involved in gastrulation	P	Any process that stops, prevents or reduces the frequency, rate or extent of convergent extension involved in gastrulation.
1904105	positive regulation of convergent extension involved in gastrulation	P	Any process that activates or increases the frequency, rate or extent of convergent extension involved in gastrulation.
1904106	protein localization to microvillus	P	A process in which a protein is transported to, or maintained in, a location within a microvillus.
1904107	protein localization to microvillus membrane	P	A process in which a protein is transported to, or maintained in, a location within a microvillus membrane.
1904108	protein localization to ciliary inversin compartment	P	A process in which a protein is transported to, or maintained in, a location within a ciliary inversin compartment.
1904109	positive regulation of cholesterol import	P	Any process that activates or increases the frequency, rate or extent of cholesterol import.
1904110	regulation of plus-end directed microfilament motor activity	P	Any process that modulates the frequency, rate or extent of plus-end directed microfilament motor activity.
1904111	negative regulation of plus-end directed microfilament motor activity	P	Any process that stops, prevents or reduces the frequency, rate or extent of plus-end directed microfilament motor activity.
1904112	positive regulation of plus-end directed microfilament motor activity	P	Any process that activates or increases the frequency, rate or extent of plus-end directed microfilament motor activity.
1904113	negative regulation of muscle filament sliding	P	Any process that stops, prevents or reduces the frequency, rate or extent of muscle filament sliding.
1904114	positive regulation of muscle filament sliding	P	Any process that activates or increases the frequency, rate or extent of muscle filament sliding.
1904115	axon cytoplasm	C	Any cytoplasm that is part of a axon.
1904116	response to vasopressin	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vasopressin stimulus.
1904117	cellular response to vasopressin	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a vasopressin stimulus.
1904118	regulation of otic vesicle morphogenesis	P	Any process that modulates the frequency, rate or extent of otic vesicle morphogenesis.
1904119	negative regulation of otic vesicle morphogenesis	P	Any process that stops, prevents or reduces the frequency, rate or extent of otic vesicle morphogenesis.
1904120	positive regulation of otic vesicle morphogenesis	P	Any process that activates or increases the frequency, rate or extent of otic vesicle morphogenesis.
1904121	phosphatidylethanolamine transporter activity	F	Enables the directed movement of phosphatidylethanolamine into, out of or within a cell, or between cells.
1904122	positive regulation of fatty acid beta-oxidation by octopamine signaling pathway	P	An octopamine signaling pathway that results in positive regulation of fatty acid beta-oxidation.
1904123	positive regulation of fatty acid beta-oxidation by serotonin receptor signaling pathway	P	A serotonin receptor signaling pathway that results in positive regulation of fatty acid beta-oxidation.
1904124	microglial cell migration	P	The orderly movement of a microglial cell from one site to another.
1904125	convergent extension involved in rhombomere morphogenesis	P	Any convergent extension that is involved in rhombomere morphogenesis.
1904126	convergent extension involved in notochord morphogenesis	P	Any convergent extension that is involved in notochord morphogenesis.
1904127	regulation of convergent extension involved in somitogenesis	P	Any process that modulates the frequency, rate or extent of convergent extension involved in somitogenesis.
1904128	negative regulation of convergent extension involved in somitogenesis	P	Any process that stops, prevents or reduces the frequency, rate or extent of convergent extension involved in somitogenesis.
1904129	positive regulation of convergent extension involved in somitogenesis	P	Any process that activates or increases the frequency, rate or extent of convergent extension involved in somitogenesis.
1904130	regulation of convergent extension involved in neural plate elongation	P	Any process that modulates the frequency, rate or extent of convergent extension involved in neural plate elongation.
1904131	negative regulation of convergent extension involved in neural plate elongation	P	Any process that stops, prevents or reduces the frequency, rate or extent of convergent extension involved in neural plate elongation.
1904132	positive regulation of convergent extension involved in neural plate elongation	P	Any process that activates or increases the frequency, rate or extent of convergent extension involved in neural plate elongation.
1904133	regulation of convergent extension involved in rhombomere morphogenesis	P	Any process that modulates the frequency, rate or extent of convergent extension involved in rhombomere morphogenesis.
1904134	negative regulation of convergent extension involved in rhombomere morphogenesis	P	Any process that stops, prevents or reduces the frequency, rate or extent of convergent extension involved in rhombomere morphogenesis.
1904135	positive regulation of convergent extension involved in rhombomere morphogenesis	P	Any process that activates or increases the frequency, rate or extent of convergent extension involved in rhombomere morphogenesis.
1904136	regulation of convergent extension involved in notochord morphogenesis	P	Any process that modulates the frequency, rate or extent of convergent extension involved in notochord morphogenesis.
1904137	negative regulation of convergent extension involved in notochord morphogenesis	P	Any process that stops, prevents or reduces the frequency, rate or extent of convergent extension involved in notochord morphogenesis.
1904138	positive regulation of convergent extension involved in notochord morphogenesis	P	Any process that activates or increases the frequency, rate or extent of convergent extension involved in notochord morphogenesis.
1904139	regulation of microglial cell migration	P	Any process that modulates the frequency, rate or extent of microglial cell migration.
1904140	negative regulation of microglial cell migration	P	Any process that stops, prevents or reduces the frequency, rate or extent of microglial cell migration.
1904141	positive regulation of microglial cell migration	P	Any process that activates or increases the frequency, rate or extent of microglial cell migration.
1904142	negative regulation of carotenoid biosynthetic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of carotenoid biosynthetic process.
1904143	positive regulation of carotenoid biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of carotenoid biosynthetic process.
1904144	phosphatidylinositol phosphate phosphatase complex	C	A protein complex which is capable of phosphatidylinositol phosphate phosphatase activity.
1904145	negative regulation of meiotic cell cycle process involved in oocyte maturation	P	Any process that stops, prevents or reduces the frequency, rate or extent of meiotic cell cycle process involved in oocyte maturation.
1904146	positive regulation of meiotic cell cycle process involved in oocyte maturation	P	Any process that activates or increases the frequency, rate or extent of meiotic cell cycle process involved in oocyte maturation.
1904147	response to nonylphenol	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nonylphenol stimulus.
1904148	cellular response to nonylphenol	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nonylphenol stimulus.
1904149	regulation of microglial cell mediated cytotoxicity	P	Any process that modulates the frequency, rate or extent of microglial cell mediated cytotoxicity.
1904150	negative regulation of microglial cell mediated cytotoxicity	P	Any process that stops, prevents or reduces the frequency, rate or extent of microglial cell mediated cytotoxicity.
1904151	positive regulation of microglial cell mediated cytotoxicity	P	Any process that activates or increases the frequency, rate or extent of microglial cell mediated cytotoxicity.
1904152	regulation of retrograde protein transport, ER to cytosol	P	Any process that modulates the frequency, rate or extent of retrograde protein transport, ER to cytosol.
1904153	negative regulation of retrograde protein transport, ER to cytosol	P	Any process that stops, prevents or reduces the frequency, rate or extent of retrograde protein transport, ER to cytosol.
1904154	positive regulation of retrograde protein transport, ER to cytosol	P	Any process that activates or increases the frequency, rate or extent of retrograde protein transport, ER to cytosol.
1904155	DN2 thymocyte differentiation	P	The process in which a relatively unspecialized cell acquires the specialized features of a DN2 thymocyte. A DN2 thymocyte is a CD4-,CD8- thymocyte that is also CD44+,CD25-.
1904156	DN3 thymocyte differentiation	P	The process in which a relatively unspecialized cell acquires the specialized features of a DN3 thymocyte. A DN3 thymocyte is a CD4-,CD8- thymocyte that is also CD44+,CD25+.
1904157	DN4 thymocyte differentiation	P	The process in which a relatively unspecialized cell acquires the specialized features of a DN4 thymocyte. A DN4 thymocyte is a CD4-,CD8- thymocyte that is also CD44-,CD25-.
1904158	axonemal central apparatus assembly	P	The aggregation, arrangement and bonding together of a set of components to form an axonemal central apparatus.
1904159	megasporocyte differentiation	P	The process in which a relatively unspecialized cell acquires the specialized features of a megasporocyte.
1904160	protein localization to chloroplast starch grain	P	A process in which a protein is transported to, or maintained in, a location within a chloroplast starch grain.
1904161	DNA synthesis involved in UV-damage excision repair	P	Any DNA synthesis that is involved in UV-damage excision repair.
1904162	5'-3' exodeoxyribonuclease activity involved in UV-damage excision repair	F	Any 5'-3' exodeoxyribonuclease activity that is involved in UV-damage excision repair.
1904167	regulation of thyroid hormone receptor activity	P	Any process that modulates the frequency, rate or extent of thyroid hormone receptor activity.
1904168	negative regulation of thyroid hormone receptor activity	P	Any process that stops, prevents or reduces the frequency, rate or extent of thyroid hormone receptor activity.
1904169	positive regulation of thyroid hormone receptor activity	P	Any process that activates or increases the frequency, rate or extent of thyroid hormone receptor activity.
1904170	regulation of bleb assembly	P	Any process that modulates the frequency, rate or extent of bleb assembly.
1904171	negative regulation of bleb assembly	P	Any process that stops, prevents or reduces the frequency, rate or extent of bleb assembly.
1904172	positive regulation of bleb assembly	P	Any process that activates or increases the frequency, rate or extent of bleb assembly.
1904173	regulation of histone demethylase activity (H3-K4 specific)	P	Any process that modulates the frequency, rate or extent of histone demethylase activity (H3-K4 specific).
1904174	negative regulation of histone demethylase activity (H3-K4 specific)	P	Any process that stops, prevents or reduces the frequency, rate or extent of histone demethylase activity (H3-K4 specific).
1904175	positive regulation of histone demethylase activity (H3-K4 specific)	P	Any process that activates or increases the frequency, rate or extent of histone demethylase activity (H3-K4 specific).
1904176	carbon phosphorus lyase complex	C	A protein complex which is capable of carbon phosphorus lyase activity.
1904177	regulation of adipose tissue development	P	Any process that modulates the frequency, rate or extent of adipose tissue development.
1904178	negative regulation of adipose tissue development	P	Any process that stops, prevents or reduces the frequency, rate or extent of adipose tissue development.
1904179	positive regulation of adipose tissue development	P	Any process that activates or increases the frequency, rate or extent of adipose tissue development.
1904180	negative regulation of membrane depolarization	P	Any process that stops, prevents or reduces the frequency, rate or extent of membrane depolarization.
1904181	positive regulation of membrane depolarization	P	Any process that activates or increases the frequency, rate or extent of membrane depolarization.
1904182	regulation of pyruvate dehydrogenase activity	P	Any process that modulates the frequency, rate or extent of pyruvate dehydrogenase activity.
1904183	negative regulation of pyruvate dehydrogenase activity	P	Any process that stops, prevents or reduces the frequency, rate or extent of pyruvate dehydrogenase activity.
1904184	positive regulation of pyruvate dehydrogenase activity	P	Any process that activates or increases the frequency, rate or extent of pyruvate dehydrogenase activity.
1904185	equatorial microtubule organizing center assembly	P	The aggregation, arrangement and bonding together of a set of components to form an equatorial microtubule organizing center.
1904186	post-anaphase microtubule array organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly ofa post-anaphase microtubule array.
1904187	regulation of transformation of host cell by virus	P	Any process that modulates the frequency, rate or extent of transformation of host cell by virus.
1904188	negative regulation of transformation of host cell by virus	P	Any process that stops, prevents or reduces the frequency, rate or extent of transformation of host cell by virus.
1904189	positive regulation of transformation of host cell by virus	P	Any process that activates or increases the frequency, rate or extent of transformation of host cell by virus.
1904191	positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in meiotic nuclear division	P	Any positive regulation of cyclin-dependent protein serine/threonine kinase activity that is involved in meiotic nuclear division.
1904192	regulation of cholangiocyte apoptotic process	P	Any process that modulates the frequency, rate or extent of cholangiocyte apoptotic process.
1904193	negative regulation of cholangiocyte apoptotic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of cholangiocyte apoptotic process.
1904194	positive regulation of cholangiocyte apoptotic process	P	Any process that activates or increases the frequency, rate or extent of cholangiocyte apoptotic process.
1904195	regulation of granulosa cell proliferation	P	Any process that modulates the frequency, rate or extent of granulosa cell proliferation.
1904196	negative regulation of granulosa cell proliferation	P	Any process that stops, prevents or reduces the frequency, rate or extent of granulosa cell proliferation.
1904197	positive regulation of granulosa cell proliferation	P	Any process that activates or increases the frequency, rate or extent of granulosa cell proliferation.
1904198	negative regulation of regulation of vascular smooth muscle cell membrane depolarization	P	Any process that stops, prevents or reduces the frequency, rate or extent of regulation of vascular smooth muscle cell membrane depolarization.
1904199	positive regulation of regulation of vascular smooth muscle cell membrane depolarization	P	Any process that activates or increases the frequency, rate or extent of regulation of vascular smooth muscle cell membrane depolarization.
1904200	iodide transmembrane transport	P	The directed movement of iodide across a membrane.
1904201	regulation of iodide transport	P	Any process that modulates the frequency, rate or extent of iodide transport.
1904202	negative regulation of iodide transport	P	Any process that stops, prevents or reduces the frequency, rate or extent of iodide transport.
1904203	positive regulation of iodide transport	P	Any process that activates or increases the frequency, rate or extent of iodide transport.
1904204	regulation of skeletal muscle hypertrophy	P	Any process that modulates the frequency, rate or extent of skeletal muscle hypertrophy.
1904205	negative regulation of skeletal muscle hypertrophy	P	Any process that stops, prevents or reduces the frequency, rate or extent of skeletal muscle hypertrophy.
1904206	positive regulation of skeletal muscle hypertrophy	P	Any process that activates or increases the frequency, rate or extent of skeletal muscle hypertrophy.
1904207	regulation of chemokine (C-C motif) ligand 2 secretion	P	Any process that modulates the frequency, rate or extent of chemokine (C-C motif) ligand 2 secretion.
1904208	negative regulation of chemokine (C-C motif) ligand 2 secretion	P	Any process that stops, prevents or reduces the frequency, rate or extent of chemokine (C-C motif) ligand 2 secretion.
1904209	positive regulation of chemokine (C-C motif) ligand 2 secretion	P	Any process that activates or increases the frequency, rate or extent of chemokine (C-C motif) ligand 2 secretion.
1904210	VCP-NPL4-UFD1 AAA ATPase complex assembly	P	The aggregation, arrangement and bonding together of a set of components to form a VCP-NPL4-UFD1 AAA ATPase complex.
1904211	membrane protein proteolysis involved in retrograde protein transport, ER to cytosol	P	Any membrane protein proteolysis that is involved in retrograde protein transport, ER to cytosol.
1904212	regulation of iodide transmembrane transport	P	Any process that modulates the frequency, rate or extent of iodide transmembrane transport.
1904213	negative regulation of iodide transmembrane transport	P	Any process that stops, prevents or reduces the frequency, rate or extent of iodide transmembrane transport.
1904214	positive regulation of iodide transmembrane transport	P	Any process that activates or increases the frequency, rate or extent of iodide transmembrane transport.
1904215	regulation of protein import into chloroplast stroma	P	Any process that modulates the frequency, rate or extent of protein import into chloroplast stroma.
1904216	positive regulation of protein import into chloroplast stroma	P	Any process that activates or increases the frequency, rate or extent of protein import into chloroplast stroma.
1904217	regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity	P	Any process that modulates the frequency, rate or extent of CDP-diacylglycerol-serine O-phosphatidyltransferase activity.
1904218	negative regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity	P	Any process that stops, prevents or reduces the frequency, rate or extent of CDP-diacylglycerol-serine O-phosphatidyltransferase activity.
1904219	positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity	P	Any process that activates or increases the frequency, rate or extent of CDP-diacylglycerol-serine O-phosphatidyltransferase activity.
1904220	regulation of serine C-palmitoyltransferase activity	P	Any process that modulates the frequency, rate or extent of serine C-palmitoyltransferase activity.
1904221	negative regulation of serine C-palmitoyltransferase activity	P	Any process that stops, prevents or reduces the frequency, rate or extent of serine C-palmitoyltransferase activity.
1904222	positive regulation of serine C-palmitoyltransferase activity	P	Any process that activates or increases the frequency, rate or extent of serine C-palmitoyltransferase activity.
1904223	regulation of glucuronosyltransferase activity	P	Any process that modulates the frequency, rate or extent of glucuronosyltransferase activity.
1904224	negative regulation of glucuronosyltransferase activity	P	Any process that stops, prevents or reduces the frequency, rate or extent of glucuronosyltransferase activity.
1904225	positive regulation of glucuronosyltransferase activity	P	Any process that activates or increases the frequency, rate or extent of glucuronosyltransferase activity.
1904226	regulation of glycogen synthase activity, transferring glucose-1-phosphate	P	Any process that modulates the frequency, rate or extent of glycogen synthase activity, transferring glucose-1-phosphate.
1904227	negative regulation of glycogen synthase activity, transferring glucose-1-phosphate	P	Any process that stops, prevents or reduces the frequency, rate or extent of glycogen synthase activity, transferring glucose-1-phosphate.
1904228	positive regulation of glycogen synthase activity, transferring glucose-1-phosphate	P	Any process that activates or increases the frequency, rate or extent of glycogen synthase activity, transferring glucose-1-phosphate.
1904229	regulation of succinate dehydrogenase activity	P	Any process that modulates the frequency, rate or extent of succinate dehydrogenase activity.
1904230	negative regulation of succinate dehydrogenase activity	P	Any process that stops, prevents or reduces the frequency, rate or extent of succinate dehydrogenase activity.
1904231	positive regulation of succinate dehydrogenase activity	P	Any process that activates or increases the frequency, rate or extent of succinate dehydrogenase activity.
1904232	regulation of aconitate hydratase activity	P	Any process that modulates the frequency, rate or extent of aconitate hydratase activity.
1904233	negative regulation of aconitate hydratase activity	P	Any process that stops, prevents or reduces the frequency, rate or extent of aconitate hydratase activity.
1904234	positive regulation of aconitate hydratase activity	P	Any process that activates or increases the frequency, rate or extent of aconitate hydratase activity.
1904235	regulation of substrate-dependent cell migration, cell attachment to substrate	P	Any process that modulates the frequency, rate or extent of substrate-dependent cell migration, cell attachment to substrate.
1904236	negative regulation of substrate-dependent cell migration, cell attachment to substrate	P	Any process that stops, prevents or reduces the frequency, rate or extent of substrate-dependent cell migration, cell attachment to substrate.
1904237	positive regulation of substrate-dependent cell migration, cell attachment to substrate	P	Any process that activates or increases the frequency, rate or extent of substrate-dependent cell migration, cell attachment to substrate.
1904238	pericyte cell differentiation	P	The process in which a relatively unspecialized cell acquires the specialized features of a pericyte cell.
1904239	regulation of VCP-NPL4-UFD1 AAA ATPase complex assembly	P	Any process that modulates the frequency, rate or extent of VCP-NPL4-UFD1 AAA ATPase complex assembly.
1904240	negative regulation of VCP-NPL4-UFD1 AAA ATPase complex assembly	P	Any process that stops, prevents or reduces the frequency, rate or extent of VCP-NPL4-UFD1 AAA ATPase complex assembly.
1904241	positive regulation of VCP-NPL4-UFD1 AAA ATPase complex assembly	P	Any process that activates or increases the frequency, rate or extent of VCP-NPL4-UFD1 AAA ATPase complex assembly.
1904242	regulation of pancreatic trypsinogen secretion	P	Any process that modulates the frequency, rate or extent of pancreatic trypsinogen secretion.
1904243	negative regulation of pancreatic trypsinogen secretion	P	Any process that stops, prevents or reduces the frequency, rate or extent of pancreatic trypsinogen secretion.
1904244	positive regulation of pancreatic trypsinogen secretion	P	Any process that activates or increases the frequency, rate or extent of pancreatic trypsinogen secretion.
1904245	regulation of polynucleotide adenylyltransferase activity	P	Any process that modulates the frequency, rate or extent of polynucleotide adenylyltransferase activity.
1904246	negative regulation of polynucleotide adenylyltransferase activity	P	Any process that stops, prevents or reduces the frequency, rate or extent of polynucleotide adenylyltransferase activity.
1904247	positive regulation of polynucleotide adenylyltransferase activity	P	Any process that activates or increases the frequency, rate or extent of polynucleotide adenylyltransferase activity.
1904248	regulation of age-related resistance	P	Any process that modulates the extent of age-related resistance.
1904249	negative regulation of age-related resistance	P	Any process that stops, prevents or reduces the extent of age-related resistance.
1904250	positive regulation of age-related resistance	P	Any process that activates or increases the extent of age-related resistance.
1904251	regulation of bile acid metabolic process	P	Any process that modulates the frequency, rate or extent of bile acid metabolic process.
1904252	negative regulation of bile acid metabolic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of bile acid metabolic process.
1904253	positive regulation of bile acid metabolic process	P	Any process that activates or increases the frequency, rate or extent of bile acid metabolic process.
1904254	regulation of iron channel activity	P	Any process that modulates the frequency, rate or extent of iron channel activity.
1904255	negative regulation of iron channel activity	P	Any process that stops, prevents or reduces the frequency, rate or extent of iron channel activity.
1904256	positive regulation of iron channel activity	P	Any process that activates or increases the frequency, rate or extent of iron channel activity.
1904257	zinc II ion import across Golgi membrane	P	The directed import of zinc(2+) from the cytosol across the Golgi membrane into the Golgi apparatus.
1904258	nuclear dicing body assembly	P	The aggregation, arrangement and bonding together of a set of components to form a nuclear dicing body.
1904259	regulation of basement membrane assembly involved in embryonic body morphogenesis	P	Any process that modulates the frequency, rate or extent of basement membrane assembly involved in embryonic body morphogenesis.
1904260	negative regulation of basement membrane assembly involved in embryonic body morphogenesis	P	Any process that stops, prevents or reduces the frequency, rate or extent of basement membrane assembly involved in embryonic body morphogenesis.
1904261	positive regulation of basement membrane assembly involved in embryonic body morphogenesis	P	Any process that activates or increases the frequency, rate or extent of basement membrane assembly involved in embryonic body morphogenesis.
1904262	negative regulation of TORC1 signaling	P	Any process that stops, prevents or reduces the frequency, rate or extent of TORC1 signaling.
1904263	positive regulation of TORC1 signaling	P	Any process that activates or increases the frequency, rate or extent of TORC1 signaling.
1904264	ubiquitin protein ligase activity involved in ERAD pathway	F	Any ubiquitin protein ligase activity that is involved in the ERAD pathway (the targeting of endoplasmic reticulum (ER)-resident proteins for degradation by the cytoplasmic proteasome).
1904265	ubiquitin-specific protease activity involved in negative regulation of retrograde protein transport, ER to cytosol	F	Any ubiquitin-specific protease activity (deubiquitinase activity) that is involved in negative regulation of retrograde protein transport, ER to cytosol.
1904266	regulation of Schwann cell chemotaxis	P	Any process that modulates the frequency, rate or extent of Schwann cell chemotaxis.
1904267	negative regulation of Schwann cell chemotaxis	P	Any process that stops, prevents or reduces the frequency, rate or extent of Schwann cell chemotaxis.
1904268	positive regulation of Schwann cell chemotaxis	P	Any process that activates or increases the frequency, rate or extent of Schwann cell chemotaxis.
1904269	cell leading edge cell cortex	C	The cell cortex of the leading edge of a cell.
1904270	pyroptosome complex assembly	P	The aggregation, arrangement and bonding together of a set of components to form a pyroptosome complex.
1904271	L-proline import across plasma membrane	P	The directed movement of L-proline from outside of a cell into the cytoplasmic compartment.
1904272	L-tryptophan import across plasma membrane	P	The directed movement of L-tryptophan from outside of a cell into the cytoplasmic compartment.
1904273	L-alanine import across plasma membrane	P	The directed import of L-alanine from the extracellular region across the plasma membrane and into the cytosol.
1904274	tricellular tight junction assembly	P	The aggregation, arrangement and bonding together of a set of components to form a tricellular tight junction.
1904275	tricellular tight junction disassembly	P	The disaggregation of a tricellular tight junction into its constituent components.
1904276	regulation of wax biosynthetic process	P	Any process that modulates the frequency, rate or extent of wax biosynthetic process.
1904277	negative regulation of wax biosynthetic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of wax biosynthetic process.
1904278	positive regulation of wax biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of wax biosynthetic process.
1904279	regulation of transcription from RNA polymerase V promoter	P	Any process that modulates the frequency, rate or extent of transcription from RNA polymerase V promoter.
1904280	negative regulation of transcription from RNA polymerase V promoter	P	Any process that stops, prevents or reduces the frequency, rate or extent of transcription from RNA polymerase V promoter.
1904281	positive regulation of transcription from RNA polymerase V promoter	P	Any process that activates or increases the frequency, rate or extent of transcription from RNA polymerase V promoter.
1904282	regulation of antigen processing and presentation of endogenous peptide antigen via MHC class I	P	Any process that modulates the frequency, rate or extent of antigen processing and presentation of endogenous peptide antigen via MHC class I.
1904283	negative regulation of antigen processing and presentation of endogenous peptide antigen via MHC class I	P	Any process that stops, prevents or reduces the frequency, rate or extent of antigen processing and presentation of endogenous peptide antigen via MHC class I.
1904284	positive regulation of antigen processing and presentation of endogenous peptide antigen via MHC class I	P	Any process that activates or increases the frequency, rate or extent of antigen processing and presentation of endogenous peptide antigen via MHC class I.
1904285	regulation of protein-pyridoxal-5-phosphate linkage	P	Any process that modulates the frequency, rate or extent of protein-pyridoxal-5-phosphate linkage.
1904286	negative regulation of protein-pyridoxal-5-phosphate linkage	P	Any process that stops, prevents or reduces the frequency, rate or extent of protein-pyridoxal-5-phosphate linkage.
1904287	positive regulation of protein-pyridoxal-5-phosphate linkage	P	Any process that activates or increases the frequency, rate or extent of protein-pyridoxal-5-phosphate linkage.
1904288	BAT3 complex binding	F	Interacting selectively and non-covalently with a BAT3 complex.
1904289	regulation of mitotic DNA damage checkpoint	P	Any process that modulates the frequency, rate or extent of mitotic DNA damage checkpoint.
1904290	negative regulation of mitotic DNA damage checkpoint	P	Any process that stops, prevents or reduces the frequency, rate or extent of mitotic DNA damage checkpoint.
1904291	positive regulation of mitotic DNA damage checkpoint	P	Any process that activates or increases the frequency, rate or extent of mitotic DNA damage checkpoint.
1904292	regulation of ERAD pathway	P	Any process that modulates the frequency, rate or extent of ERAD pathway.
1904293	negative regulation of ERAD pathway	P	Any process that stops, prevents or reduces the frequency, rate or extent of ERAD pathway.
1904294	positive regulation of ERAD pathway	P	Any process that activates or increases the frequency, rate or extent of ERAD pathway.
1904295	regulation of osmolarity-sensing cation channel activity	P	Any process that modulates the frequency, rate or extent of osmolarity-sensing cation channel activity.
1904296	negative regulation of osmolarity-sensing cation channel activity	P	Any process that stops, prevents or reduces the frequency, rate or extent of osmolarity-sensing cation channel activity.
1904297	positive regulation of osmolarity-sensing cation channel activity	P	Any process that activates or increases the frequency, rate or extent of osmolarity-sensing cation channel activity.
1904298	regulation of transcytosis	P	Any process that modulates the frequency, rate or extent of transcytosis.
1904299	negative regulation of transcytosis	P	Any process that stops, prevents or reduces the frequency, rate or extent of transcytosis.
1904300	positive regulation of transcytosis	P	Any process that activates or increases the frequency, rate or extent of transcytosis.
1904301	regulation of maternal process involved in parturition	P	Any process that modulates the frequency, rate or extent of maternal process involved in parturition.
1904302	negative regulation of maternal process involved in parturition	P	Any process that stops, prevents or reduces the frequency, rate or extent of maternal process involved in parturition.
1904303	positive regulation of maternal process involved in parturition	P	Any process that activates or increases the frequency, rate or extent of maternal process involved in parturition.
1904304	regulation of gastro-intestinal system smooth muscle contraction	P	Any process that modulates the frequency, rate or extent of gastro-intestinal system smooth muscle contraction.
1904305	negative regulation of gastro-intestinal system smooth muscle contraction	P	Any process that stops, prevents or reduces the frequency, rate or extent of gastro-intestinal system smooth muscle contraction.
1904306	positive regulation of gastro-intestinal system smooth muscle contraction	P	Any process that activates or increases the frequency, rate or extent of gastro-intestinal system smooth muscle contraction.
1904307	response to desipramine	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a desipramine stimulus.
1904308	cellular response to desipramine	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a desipramine stimulus.
1904309	response to cordycepin	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cordycepin stimulus.
1904310	cellular response to cordycepin	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cordycepin stimulus.
1904311	response to gold(3+)	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gold(3+) stimulus.
1904312	cellular response to gold(3+)	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gold(3+) stimulus.
1904313	response to methamphetamine hydrochloride	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methamphetamine hydrochloride stimulus.
1904314	cellular response to methamphetamine hydrochloride	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methamphetamine hydrochloride stimulus.
1904315	transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential	F	Any transmitter-gated ion channel activity that is involved in regulation of postsynaptic membrane potential.
1904316	response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine stimulus.
1904317	cellular response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine stimulus.
1904318	regulation of smooth muscle contraction involved in micturition	P	Any process that modulates the frequency, rate or extent of smooth muscle contraction involved in micturition.
1904319	negative regulation of smooth muscle contraction involved in micturition	P	Any process that stops, prevents or reduces the frequency, rate or extent of smooth muscle contraction involved in micturition.
1904320	positive regulation of smooth muscle contraction involved in micturition	P	Any process that activates or increases the frequency, rate or extent of smooth muscle contraction involved in micturition.
1904321	response to forskolin	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a forskolin stimulus.
1904322	cellular response to forskolin	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a forskolin stimulus.
1904323	regulation of inhibitory G-protein coupled receptor phosphorylation	P	Any process that modulates the frequency, rate or extent of inhibitory G-protein coupled receptor phosphorylation.
1904324	negative regulation of inhibitory G-protein coupled receptor phosphorylation	P	Any process that stops, prevents or reduces the frequency, rate or extent of inhibitory G-protein coupled receptor phosphorylation.
1904325	positive regulation of inhibitory G-protein coupled receptor phosphorylation	P	Any process that activates or increases the frequency, rate or extent of inhibitory G-protein coupled receptor phosphorylation.
1904326	negative regulation of circadian sleep/wake cycle, wakefulness	P	Any process that stops, prevents or reduces the frequency, rate or extent of circadian sleep/wake cycle, wakefulness.
1904327	protein localization to cytosolic proteasome complex	P	A process in which a protein is transported to, or maintained in, a location within a cytosolic proteasome complex.
1904328	regulation of myofibroblast contraction	P	Any process that modulates the frequency, rate or extent of myofibroblast contraction.
1904329	negative regulation of myofibroblast contraction	P	Any process that stops, prevents or reduces the frequency, rate or extent of myofibroblast contraction.
1904330	positive regulation of myofibroblast contraction	P	Any process that activates or increases the frequency, rate or extent of myofibroblast contraction.
1904331	regulation of error-prone translesion synthesis	P	Any process that modulates the frequency, rate or extent of error-prone translesion synthesis.
1904332	negative regulation of error-prone translesion synthesis	P	Any process that stops, prevents or reduces the frequency, rate or extent of error-prone translesion synthesis.
1904333	positive regulation of error-prone translesion synthesis	P	Any process that activates or increases the frequency, rate or extent of error-prone translesion synthesis.
1904334	heme import across plasma membrane	P	The directed movement of heme from outside of a cell into the cytoplasmic compartment.
1904335	regulation of ductus arteriosus closure	P	Any process that modulates the frequency, rate or extent of ductus arteriosus closure.
1904336	negative regulation of ductus arteriosus closure	P	Any process that stops, prevents or reduces the frequency, rate or extent of ductus arteriosus closure.
1904337	positive regulation of ductus arteriosus closure	P	Any process that activates or increases the frequency, rate or extent of ductus arteriosus closure.
1904338	regulation of dopaminergic neuron differentiation	P	Any process that modulates the frequency, rate or extent of dopaminergic neuron differentiation.
1904339	negative regulation of dopaminergic neuron differentiation	P	Any process that stops, prevents or reduces the frequency, rate or extent of dopaminergic neuron differentiation.
1904340	positive regulation of dopaminergic neuron differentiation	P	Any process that activates or increases the frequency, rate or extent of dopaminergic neuron differentiation.
1904341	regulation of colon smooth muscle contraction	P	Any process that modulates the frequency, rate or extent of colon smooth muscle contraction.
1904342	negative regulation of colon smooth muscle contraction	P	Any process that stops, prevents or reduces the frequency, rate or extent of colon smooth muscle contraction.
1904343	positive regulation of colon smooth muscle contraction	P	Any process that activates or increases the frequency, rate or extent of colon smooth muscle contraction.
1904344	regulation of gastric mucosal blood circulation	P	Any process that modulates the frequency, rate or extent of gastric mucosal blood circulation.
1904345	negative regulation of gastric mucosal blood circulation	P	Any process that stops, prevents or reduces the frequency, rate or extent of gastric mucosal blood circulation.
1904346	positive regulation of gastric mucosal blood circulation	P	Any process that activates or increases the frequency, rate or extent of gastric mucosal blood circulation.
1904347	regulation of small intestine smooth muscle contraction	P	Any process that modulates the frequency, rate or extent of small intestine smooth muscle contraction.
1904348	negative regulation of small intestine smooth muscle contraction	P	Any process that stops, prevents or reduces the frequency, rate or extent of small intestine smooth muscle contraction.
1904349	positive regulation of small intestine smooth muscle contraction	P	Any process that activates or increases the frequency, rate or extent of small intestine smooth muscle contraction.
1904350	regulation of protein catabolic process in the vacuole	P	Any process that modulates the frequency, rate or extent of protein catabolic process in the vacuole.
1904351	negative regulation of protein catabolic process in the vacuole	P	Any process that stops, prevents or reduces the frequency, rate or extent of protein catabolic process in the vacuole.
1904352	positive regulation of protein catabolic process in the vacuole	P	Any process that activates or increases the frequency, rate or extent of protein catabolic process in the vacuole.
1904353	regulation of telomere capping	P	Any process that modulates the frequency, rate or extent of telomere capping.
1904354	negative regulation of telomere capping	P	Any process that stops, prevents or reduces the frequency, rate or extent of telomere capping.
1904355	positive regulation of telomere capping	P	Any process that activates or increases the frequency, rate or extent of telomere capping.
1904356	regulation of telomere maintenance via telomere lengthening	P	Any process that modulates the frequency, rate or extent of telomere maintenance via telomere lengthening.
1904357	negative regulation of telomere maintenance via telomere lengthening	P	Any process that stops, prevents or reduces the frequency, rate or extent of telomere maintenance via telomere lengthening.
1904358	positive regulation of telomere maintenance via telomere lengthening	P	Any process that activates or increases the frequency, rate or extent of telomere maintenance via telomere lengthening.
1904359	regulation of spore germination	P	Any process that modulates the frequency, rate or extent of spore germination.
1904360	negative regulation of spore germination	P	Any process that stops, prevents or reduces the frequency, rate or extent of spore germination.
1904361	positive regulation of spore germination	P	Any process that activates or increases the frequency, rate or extent of spore germination.
1904362	regulation of calcitonin secretion	P	Any process that modulates the frequency, rate or extent of calcitonin secretion.
1904363	negative regulation of calcitonin secretion	P	Any process that stops, prevents or reduces the frequency, rate or extent of calcitonin secretion.
1904364	positive regulation of calcitonin secretion	P	Any process that activates or increases the frequency, rate or extent of calcitonin secretion.
1904365	regulation of chemokinesis	P	Any process that modulates the frequency, rate or extent of chemokinesis.
1904366	negative regulation of chemokinesis	P	Any process that stops, prevents or reduces the frequency, rate or extent of chemokinesis.
1904367	positive regulation of chemokinesis	P	Any process that activates or increases the frequency, rate or extent of chemokinesis.
1904368	regulation of sclerenchyma cell differentiation	P	Any process that modulates the frequency, rate or extent of sclerenchyma cell differentiation.
1904369	positive regulation of sclerenchyma cell differentiation	P	Any process that activates or increases the frequency, rate or extent of sclerenchyma cell differentiation.
1904370	regulation of protein localization to actin cortical patch	P	Any process that modulates the frequency, rate or extent of protein localization to actin cortical patch.
1904371	negative regulation of protein localization to actin cortical patch	P	Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to actin cortical patch.
1904372	positive regulation of protein localization to actin cortical patch	P	Any process that activates or increases the frequency, rate or extent of protein localization to actin cortical patch.
1904373	response to kainic acid	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a kainic acid stimulus.
1904374	cellular response to kainic acid	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a kainic acid stimulus.
1904375	regulation of protein localization to cell periphery	P	Any process that modulates the frequency, rate or extent of protein localization to cell periphery.
1904376	negative regulation of protein localization to cell periphery	P	Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cell periphery.
1904377	positive regulation of protein localization to cell periphery	P	Any process that activates or increases the frequency, rate or extent of protein localization to cell periphery.
1904378	maintenance of unfolded protein involved in ERAD pathway	P	Maintaining an endoplasmic reticulum (ER) protein in an unfolded, soluble state that contributes to its degradation by the cytoplasmic proteasome. Maintaining ER-resident proteins in an unfolded yet soluble state condition after their retro-translocation favors their turnover by the cytosolic proteasome.
1904379	protein localization to cytosolic proteasome complex involved in ERAD pathway	P	Any protein localization to cytosolic proteasome complex that is involved in ERAD pathway. Following their retrotranslocation out of the endoplasmic reticulum, protein substrates must be shuttled to the cytosolic proteasome for degradation.
1904380	endoplasmic reticulum mannose trimming	P	Any protein alpha-1,2-demannosylation that takes place in the endoplasmic reticulum quality control compartment (ERQC).
1904381	Golgi apparatus mannose trimming	P	Any protein alpha-1,2-demannosylation that takes place in the Golgi apparatus.
1904382	mannose trimming involved in glycoprotein ERAD pathway	P	The removal of one or more alpha 1,2-linked mannose residues from a mannosylated protein that occurs as part of glycoprotein ER-associated glycoprotein degradation (gpERAD).
1904383	response to sodium phosphate	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sodium phosphate stimulus.
1904384	cellular response to sodium phosphate	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sodium phosphate stimulus.
1904385	cellular response to angiotensin	P	"Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an angiotensin stimulus. Angiotensin is any of three physiologically active peptides (angiotensin II, III, or IV) processed from angiotensinogen."
1904386	response to L-phenylalanine derivative	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-phenylalanine derivative stimulus.
1904387	cellular response to L-phenylalanine derivative	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-phenylalanine derivative stimulus.
1904388	negative regulation of ncRNA transcription associated with protein coding gene TSS/TES	P	Any process that stops, prevents or reduces the frequency, rate or extent of ncRNA transcription associated with protein coding gene TSS/TES.
1904389	rod bipolar cell differentiation	P	The process in which a relatively unspecialized cell acquires the specialized features of a rod bipolar cell.
1904390	cone retinal bipolar cell differentiation	P	The process in which a relatively unspecialized cell acquires the specialized features of a cone retinal bipolar cell.
1904391	response to ciliary neurotrophic factor	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ciliary neurotrophic factor stimulus.
1904392	cellular response to ciliary neurotrophic factor	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ciliary neurotrophic factor stimulus.
1904393	regulation of skeletal muscle acetylcholine-gated channel clustering	P	Any process that modulates the frequency, rate or extent of skeletal muscle acetylcholine-gated channel clustering.
1904394	negative regulation of skeletal muscle acetylcholine-gated channel clustering	P	Any process that stops, prevents or reduces the frequency, rate or extent of skeletal muscle acetylcholine-gated channel clustering.
1904395	positive regulation of skeletal muscle acetylcholine-gated channel clustering	P	Any process that activates or increases the frequency, rate or extent of skeletal muscle acetylcholine-gated channel clustering.
1904396	regulation of neuromuscular junction development	P	Any process that modulates the frequency, rate or extent of neuromuscular junction development.
1904397	negative regulation of neuromuscular junction development	P	Any process that stops, prevents or reduces the frequency, rate or extent of neuromuscular junction development.
1904398	positive regulation of neuromuscular junction development	P	Any process that activates or increases the frequency, rate or extent of neuromuscular junction development.
1904399	heparan sulfate binding	F	Interacting selectively and non-covalently with heparan sulfate.
1904400	response to Thyroid stimulating hormone	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a Thyroid stimulating hormone stimulus.
1904401	cellular response to Thyroid stimulating hormone	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a Thyroid stimulating hormone stimulus.
1904402	response to nocodazole	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nocodazole stimulus.
1904403	cellular response to nocodazole	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nocodazole stimulus.
1904404	response to formaldehyde	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a formaldehyde stimulus.
1904405	cellular response to formaldehyde	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a formaldehyde stimulus.
1904406	negative regulation of nitric oxide metabolic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of nitric oxide metabolic process.
1904407	positive regulation of nitric oxide metabolic process	P	Any process that activates or increases the frequency, rate or extent of nitric oxide metabolic process.
1904408	melatonin binding	F	Interacting selectively and non-covalently with melatonin.
1904409	regulation of secretory granule organization	P	Any process that modulates the frequency, rate or extent of secretory granule organization.
1904410	negative regulation of secretory granule organization	P	Any process that stops, prevents or reduces the frequency, rate or extent of secretory granule organization.
1904411	positive regulation of secretory granule organization	P	Any process that activates or increases the frequency, rate or extent of secretory granule organization.
1904412	regulation of cardiac ventricle development	P	Any process that modulates the frequency, rate or extent of cardiac ventricle development.
1904413	negative regulation of cardiac ventricle development	P	Any process that stops, prevents or reduces the frequency, rate or extent of cardiac ventricle development.
1904414	positive regulation of cardiac ventricle development	P	Any process that activates or increases the frequency, rate or extent of cardiac ventricle development.
1904415	regulation of xenophagy	P	Any process that modulates the frequency, rate or extent of xenophagy.
1904416	negative regulation of xenophagy	P	Any process that stops, prevents or reduces the frequency, rate or extent of xenophagy.
1904417	positive regulation of xenophagy	P	Any process that activates or increases the frequency, rate or extent of xenophagy.
1904418	regulation of telomeric loop formation	P	Any process that modulates the frequency, rate or extent of telomeric loop formation.
1904419	negative regulation of telomeric loop formation	P	Any process that stops, prevents or reduces the frequency, rate or extent of telomeric loop formation.
1904420	positive regulation of telomeric loop formation	P	Any process that activates or increases the frequency, rate or extent of telomeric loop formation.
1904421	response to D-galactosamine	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a D-galactosamine stimulus.
1904422	cellular response to D-galactosamine	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a D-galactosamine stimulus.
1904423	dehydrodolichyl diphosphate synthase complex	C	A protein complex which is capable of dehydrodolichyl diphosphate synthase activity.
1904424	regulation of GTP binding	P	Any process that modulates the frequency, rate or extent of GTP binding.
1904425	negative regulation of GTP binding	P	Any process that stops, prevents or reduces the frequency, rate or extent of GTP binding.
1904426	positive regulation of GTP binding	P	Any process that activates or increases the frequency, rate or extent of GTP binding.
1904427	positive regulation of calcium ion transmembrane transport	P	Any process that activates or increases the frequency, rate or extent of calcium ion transmembrane transport.
1904428	negative regulation of tubulin deacetylation	P	Any process that stops, prevents or reduces the frequency, rate or extent of tubulin deacetylation.
1904429	regulation of t-circle formation	P	Any process that modulates the frequency, rate or extent of t-circle formation.
1904430	negative regulation of t-circle formation	P	Any process that stops, prevents or reduces the frequency, rate or extent of t-circle formation.
1904431	positive regulation of t-circle formation	P	Any process that activates or increases the frequency, rate or extent of t-circle formation.
1904432	regulation of ferrous iron binding	P	Any process that modulates the frequency, rate or extent of ferrous iron binding.
1904433	negative regulation of ferrous iron binding	P	Any process that stops, prevents or reduces the frequency, rate or extent of ferrous iron binding.
1904434	positive regulation of ferrous iron binding	P	Any process that activates or increases the frequency, rate or extent of ferrous iron binding.
1904435	regulation of transferrin receptor binding	P	Any process that modulates the frequency, rate or extent of transferrin receptor binding.
1904436	negative regulation of transferrin receptor binding	P	Any process that stops, prevents or reduces the frequency, rate or extent of transferrin receptor binding.
1904437	positive regulation of transferrin receptor binding	P	Any process that activates or increases the frequency, rate or extent of transferrin receptor binding.
1904438	regulation of ferrous iron import across plasma membrane	P	Any process that modulates the frequency, rate or extent of ferrous iron import across plasma membrane.
1904439	negative regulation of ferrous iron import across plasma membrane	P	Any process that stops, prevents or reduces the frequency, rate or extent of ferrous iron import across plasma membrane.
1904440	positive regulation of ferrous iron import across plasma membrane	P	Any process that activates or increases the frequency, rate or extent of ferrous iron import across plasma membrane.
1904441	regulation of thyroid gland epithelial cell proliferation	P	Any process that modulates the frequency, rate or extent of thyroid gland epithelial cell proliferation.
1904442	negative regulation of thyroid gland epithelial cell proliferation	P	Any process that stops, prevents or reduces the frequency, rate or extent of thyroid gland epithelial cell proliferation.
1904443	positive regulation of thyroid gland epithelial cell proliferation	P	Any process that activates or increases the frequency, rate or extent of thyroid gland epithelial cell proliferation.
1904444	regulation of establishment of Sertoli cell barrier	P	Any process that modulates the frequency, rate or extent of establishment of Sertoli cell barrier.
1904445	negative regulation of establishment of Sertoli cell barrier	P	Any process that stops, prevents or reduces the frequency, rate or extent of establishment of Sertoli cell barrier.
1904446	positive regulation of establishment of Sertoli cell barrier	P	Any process that activates or increases the frequency, rate or extent of establishment of Sertoli cell barrier.
1904447	folic acid import into cell	P	The directed movement of folic acid from outside of a cell, across the plasma membrane and into the cytoplasmic compartment. This may occur via transport across the plasma membrane or via endocytosis.
1904448	regulation of aspartate secretion	P	Any process that modulates the frequency, rate or extent of aspartate secretion.
1904449	negative regulation of aspartate secretion	P	Any process that stops, prevents or reduces the frequency, rate or extent of aspartate secretion.
1904450	positive regulation of aspartate secretion	P	Any process that activates or increases the frequency, rate or extent of aspartate secretion.
1904451	regulation of hydrogen:potassium-exchanging ATPase activity	P	Any process that modulates the frequency, rate or extent of hydrogen:potassium-exchanging ATPase activity.
1904452	negative regulation of hydrogen:potassium-exchanging ATPase activity	P	Any process that stops, prevents or reduces the frequency, rate or extent of hydrogen:potassium-exchanging ATPase activity.
1904453	positive regulation of hydrogen:potassium-exchanging ATPase activity	P	Any process that activates or increases the frequency, rate or extent of hydrogen:potassium-exchanging ATPase activity.
1904454	ubiquitin-specific protease activity involved in positive regulation of ERAD pathway	F	Any ubiquitin-specific protease activity that is involved in positive regulation of ERAD pathway.
1904455	ubiquitin-specific protease activity involved in negative regulation of ERAD pathway	F	Any ubiquitin-specific protease activity that is involved in negative regulation of ERAD pathway.
1904456	negative regulation of neuronal action potential	P	Any process that stops, prevents or reduces the frequency, rate or extent of neuronal action potential.
1904457	positive regulation of neuronal action potential	P	Any process that activates or increases the frequency, rate or extent of neuronal action potential.
1904458	regulation of substance P secretion	P	Any process that modulates the frequency, rate or extent of substance P secretion.
1904459	negative regulation of substance P secretion	P	Any process that stops, prevents or reduces the frequency, rate or extent of substance P secretion.
1904460	positive regulation of substance P secretion	P	Any process that activates or increases the frequency, rate or extent of substance P secretion.
1904461	ergosteryl 3-beta-D-glucoside metabolic process	P	The chemical reactions and pathways involving ergosteryl 3-beta-D-glucoside.
1904462	ergosteryl 3-beta-D-glucoside catabolic process	P	The chemical reactions and pathways resulting in the breakdown of ergosteryl 3-beta-D-glucoside.
1904463	ergosteryl 3-beta-D-glucoside biosynthetic process	P	The chemical reactions and pathways resulting in the formation of ergosteryl 3-beta-D-glucoside.
1904464	regulation of matrix metallopeptidase secretion	P	Any process that modulates the frequency, rate or extent of matrix metallopeptidase secretion.
1904465	negative regulation of matrix metallopeptidase secretion	P	Any process that stops, prevents or reduces the frequency, rate or extent of matrix metallopeptidase secretion.
1904466	positive regulation of matrix metallopeptidase secretion	P	Any process that activates or increases the frequency, rate or extent of matrix metallopeptidase secretion.
1904467	regulation of tumor necrosis factor secretion	P	Any process that modulates the frequency, rate or extent of tumor necrosis factor secretion.
1904468	negative regulation of tumor necrosis factor secretion	P	Any process that stops, prevents or reduces the frequency, rate or extent of tumor necrosis factor secretion.
1904469	positive regulation of tumor necrosis factor secretion	P	Any process that activates or increases the frequency, rate or extent of tumor necrosis factor secretion.
1904470	regulation of endothelin secretion	P	Any process that modulates the frequency, rate or extent of endothelin secretion.
1904471	negative regulation of endothelin secretion	P	Any process that stops, prevents or reduces the frequency, rate or extent of endothelin secretion.
1904472	positive regulation of endothelin secretion	P	Any process that activates or increases the frequency, rate or extent of endothelin secretion.
1904473	response to L-dopa	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-dopa stimulus.
1904474	cellular response to L-dopa	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-dopa stimulus.
1904475	regulation of Ras GTPase binding	P	Any process that modulates the frequency, rate or extent of Ras GTPase binding.
1904476	negative regulation of Ras GTPase binding	P	Any process that stops, prevents or reduces the frequency, rate or extent of Ras GTPase binding.
1904477	positive regulation of Ras GTPase binding	P	Any process that activates or increases the frequency, rate or extent of Ras GTPase binding.
1904478	regulation of intestinal absorption	P	Any process that modulates the frequency, rate or extent of intestinal absorption.
1904479	negative regulation of intestinal absorption	P	Any process that stops, prevents or reduces the frequency, rate or extent of intestinal absorption.
1904480	positive regulation of intestinal absorption	P	Any process that activates or increases the frequency, rate or extent of intestinal absorption.
1904481	response to tetrahydrofolate	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tetrahydrofolate stimulus.
1904482	cellular response to tetrahydrofolate	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tetrahydrofolate stimulus.
1904483	synthetic cannabinoid binding	F	Interacting selectively and non-covalently with synthetic cannabinoid.
1904484	cloacal gland development	P	The process whose specific outcome is the progression of a cloacal gland over time, from its formation to the mature structure.
1904486	response to 17alpha-ethynylestradiol	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 17alpha-ethynylestradiol stimulus.
1904487	cellular response to 17alpha-ethynylestradiol	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 17alpha-ethynylestradiol stimulus.
1904488	regulation of reactive oxygen species metabolic process by positive regulation of transcription from RNA polymerase II promoter	P	A positive regulation of transcription from RNA polymerase II promoter that results in regulation of reactive oxygen species metabolic process.
1904489	regulation of reactive oxygen species metabolic process by negative regulation of transcription from RNA polymerase II promoter	P	A negative regulation of transcription from RNA polymerase II promoter that results in regulation of reactive oxygen species metabolic process.
1904490	negative regulation of mitochondrial unfolded protein response by negative regulation of transcription from RNA polymerase II promoter	P	A negative regulation of transcription from RNA polymerase II promoter that results in negative regulation of mitochondrial unfolded protein response.
1904491	protein localization to ciliary transition zone	P	A process in which a protein is transported to, or maintained in, a location within a ciliary transition zone.
1904492	Ac-Asp-Glu binding	F	Interacting selectively and non-covalently with Ac-Asp-Glu.
1904493	tetrahydrofolyl-poly(glutamate) polymer binding	F	Interacting selectively and non-covalently with tetrahydrofolyl-poly(glutamate) polymer.
1904494	regulation of substance P secretion, neurotransmission	P	Any process that modulates the frequency, rate or extent of substance P secretion, neurotransmission.
1904495	negative regulation of substance P secretion, neurotransmission	P	Any process that stops, prevents or reduces the frequency, rate or extent of substance P secretion, neurotransmission.
1904496	positive regulation of substance P secretion, neurotransmission	P	Any process that activates or increases the frequency, rate or extent of substance P secretion, neurotransmission.
1904497	heterochromatin assembly involved in chromatin silencing at centromere outer repeat region	P	Any heterochromatin assembly that is involved in chromatin silencing at the centromere outer repeat region.
1904498	protein localization to actomyosin contractile ring involved in mitotic cytokinesis	P	Any protein localization to actomyosin contractile ring that is involved in mitotic cytokinesis.
1904499	regulation of chromatin-mediated maintenance of transcription	P	Any process that modulates the frequency, rate or extent of chromatin-mediated maintenance of transcription.
1904500	negative regulation of chromatin-mediated maintenance of transcription	P	Any process that stops, prevents or reduces the frequency, rate or extent of chromatin-mediated maintenance of transcription.
1904501	positive regulation of chromatin-mediated maintenance of transcription	P	Any process that activates or increases the frequency, rate or extent of chromatin-mediated maintenance of transcription.
1904502	regulation of lipophagy	P	Any process that modulates the frequency, rate or extent of lipophagy.
1904503	negative regulation of lipophagy	P	Any process that stops, prevents or reduces the frequency, rate or extent of lipophagy.
1904504	positive regulation of lipophagy	P	Any process that activates or increases the frequency, rate or extent of lipophagy.
1904505	regulation of telomere maintenance in response to DNA damage	P	Any process that modulates the frequency, rate or extent of telomere maintenance in response to DNA damage.
1904506	negative regulation of telomere maintenance in response to DNA damage	P	Any process that stops, prevents or reduces the frequency, rate or extent of telomere maintenance in response to DNA damage.
1904507	positive regulation of telomere maintenance in response to DNA damage	P	Any process that activates or increases the frequency, rate or extent of telomere maintenance in response to DNA damage.
1904508	regulation of protein localization to basolateral plasma membrane	P	Any process that modulates the frequency, rate or extent of protein localization to basolateral plasma membrane.
1904509	negative regulation of protein localization to basolateral plasma membrane	P	Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to basolateral plasma membrane.
1904510	positive regulation of protein localization to basolateral plasma membrane	P	Any process that activates or increases the frequency, rate or extent of protein localization to basolateral plasma membrane.
1904511	cytoplasmic microtubule plus-end	C	Any microtubule plus-end that is part of a cytoplasmic microtubule.
1904512	regulation of initiation of premeiotic DNA replication	P	Any process that modulates the frequency, rate or extent of initiation of premeiotic DNA replication.
1904513	negative regulation of initiation of premeiotic DNA replication	P	Any process that stops, prevents or reduces the frequency, rate or extent of initiation of premeiotic DNA replication.
1904514	positive regulation of initiation of premeiotic DNA replication	P	Any process that activates or increases the frequency, rate or extent of initiation of premeiotic DNA replication.
1904515	positive regulation of TORC2 signaling	P	Any process that activates or increases the frequency, rate or extent of TORC2 signaling.
1904516	myofibroblast cell apoptotic process	P	Any apoptotic process in a myofibroblast cell.
1904517	MgATP(2-) binding	F	Interacting selectively and non-covalently with MgATP(2-).
1904518	protein localization to cytoplasmic microtubule plus-end	P	A process in which a protein is transported to, or maintained in, a location at a cytoplasmic microtubule plus-end.
1904519	protein localization to microtubule minus-end	P	A process in which a protein is transported to, or maintained in, a location at a microtubule minus-end.
1904520	regulation of myofibroblast cell apoptotic process	P	Any process that modulates the frequency, rate or extent of myofibroblast cell apoptotic process.
1904521	negative regulation of myofibroblast cell apoptotic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of myofibroblast cell apoptotic process.
1904522	positive regulation of myofibroblast cell apoptotic process	P	Any process that activates or increases the frequency, rate or extent of myofibroblast cell apoptotic process.
1904523	regulation of DNA amplification	P	Any process that modulates the frequency, rate or extent of DNA amplification.
1904524	negative regulation of DNA amplification	P	Any process that stops, prevents or reduces the frequency, rate or extent of DNA amplification.
1904525	positive regulation of DNA amplification	P	Any process that activates or increases the frequency, rate or extent of DNA amplification.
1904526	regulation of microtubule binding	P	Any process that modulates the frequency, rate or extent of microtubule binding.
1904527	negative regulation of microtubule binding	P	Any process that stops, prevents or reduces the frequency, rate or extent of microtubule binding.
1904528	positive regulation of microtubule binding	P	Any process that activates or increases the frequency, rate or extent of microtubule binding.
1904529	regulation of actin filament binding	P	Any process that modulates the frequency, rate or extent of actin filament binding.
1904530	negative regulation of actin filament binding	P	Any process that stops, prevents or reduces the frequency, rate or extent of actin filament binding.
1904531	positive regulation of actin filament binding	P	Any process that activates or increases the frequency, rate or extent of actin filament binding.
1904533	regulation of telomeric loop disassembly	P	Any process that modulates the frequency, rate or extent of telomeric loop disassembly.
1904534	negative regulation of telomeric loop disassembly	P	Any process that stops, prevents or reduces the frequency, rate or extent of telomeric loop disassembly.
1904535	positive regulation of telomeric loop disassembly	P	Any process that activates or increases the frequency, rate or extent of telomeric loop disassembly.
1904536	regulation of mitotic telomere tethering at nuclear periphery	P	Any process that modulates the frequency, rate or extent of mitotic telomere tethering at nuclear periphery.
1904537	negative regulation of mitotic telomere tethering at nuclear periphery	P	Any process that stops, prevents or reduces the frequency, rate or extent of mitotic telomere tethering at nuclear periphery.
1904538	regulation of glycolytic process through fructose-6-phosphate	P	Any process that modulates the frequency, rate or extent of glycolytic process through fructose-6-phosphate.
1904539	negative regulation of glycolytic process through fructose-6-phosphate	P	Any process that stops, prevents or reduces the frequency, rate or extent of glycolytic process through fructose-6-phosphate.
1904540	positive regulation of glycolytic process through fructose-6-phosphate	P	Any process that activates or increases the frequency, rate or extent of glycolytic process through fructose-6-phosphate.
1904541	fungal-type cell wall disassembly involved in conjugation with cellular fusion	P	Any fungal-type cell wall disassembly that is involved in conjugation with cellular fusion.
1904542	regulation of free ubiquitin chain polymerization	P	Any process that modulates the frequency, rate or extent of free ubiquitin chain polymerization.
1904543	negative regulation of free ubiquitin chain polymerization	P	Any process that stops, prevents or reduces the frequency, rate or extent of free ubiquitin chain polymerization.
1904544	positive regulation of free ubiquitin chain polymerization	P	Any process that activates or increases the frequency, rate or extent of free ubiquitin chain polymerization.
1904547	regulation of cellular response to glucose starvation	P	Any process that modulates the frequency, rate or extent of cellular response to glucose starvation.
1904550	response to arachidonic acid	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an arachidonic acid stimulus.
1904551	cellular response to arachidonic acid	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an arachidonic acid stimulus.
1904552	regulation of chemotaxis to arachidonic acid	P	Any process that modulates the frequency, rate or extent of chemotaxis to arachidonic acid.
1904553	negative regulation of chemotaxis to arachidonic acid	P	Any process that stops, prevents or reduces the frequency, rate or extent of chemotaxis to arachidonic acid.
1904554	positive regulation of chemotaxis to arachidonic acid	P	Any process that activates or increases the frequency, rate or extent of chemotaxis to arachidonic acid.
1904555	L-proline transmembrane transport	P	The directed movement of L-proline across a membrane.
1904556	L-tryptophan transmembrane transport	P	The directed movement of L-tryptophan across a membrane.
1904557	L-alanine transmembrane transport	P	The directed movement of L-alanine across a membrane.
1904558	response to dextromethorphan	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dextromethorphan stimulus.
1904559	cellular response to dextromethorphan	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dextromethorphan stimulus.
1904560	response to diphenidol	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diphenidol stimulus.
1904561	cellular response to diphenidol	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diphenidol stimulus.
1904562	phosphatidylinositol 5-phosphate metabolic process	P	The chemical reactions and pathways involving phosphatidylinositol 5-phosphate.
1904563	phosphatidylinositol 5-phosphate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of phosphatidylinositol 5-phosphate.
1904564	Nbp35-Cfd1 ATPase complex	C	An iron-sulfur cluster assembly complex that is capable of weak ATPase activity. In yeast it consists of two subunits, Nbp35 and Cfd1.
1904565	response to 1-oleoyl-sn-glycerol 3-phosphate	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 1-oleoyl-sn-glycerol 3-phosphate stimulus.
1904566	cellular response to 1-oleoyl-sn-glycerol 3-phosphate	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 1-oleoyl-sn-glycerol 3-phosphate stimulus.
1904567	response to wortmannin	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a wortmannin stimulus.
1904568	cellular response to wortmannin	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a wortmannin stimulus.
1904569	regulation of selenocysteine incorporation	P	Any process that modulates the frequency, rate or extent of selenocysteine incorporation.
1904570	negative regulation of selenocysteine incorporation	P	Any process that stops, prevents or reduces the frequency, rate or extent of selenocysteine incorporation.
1904571	positive regulation of selenocysteine incorporation	P	Any process that activates or increases the frequency, rate or extent of selenocysteine incorporation.
1904572	negative regulation of mRNA binding	P	Any process that stops, prevents or reduces the frequency, rate or extent of mRNA binding.
1904573	regulation of selenocysteine insertion sequence binding	P	Any process that modulates the frequency, rate or extent of selenocysteine insertion sequence binding.
1904574	negative regulation of selenocysteine insertion sequence binding	P	Any process that stops, prevents or reduces the frequency, rate or extent of selenocysteine insertion sequence binding.
1904575	positive regulation of selenocysteine insertion sequence binding	P	Any process that activates or increases the frequency, rate or extent of selenocysteine insertion sequence binding.
1904576	response to tunicamycin	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tunicamycin stimulus.
1904577	cellular response to tunicamycin	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tunicamycin stimulus.
1904578	response to thapsigargin	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a thapsigargin stimulus.
1904579	cellular response to thapsigargin	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a thapsigargin stimulus.
1904580	regulation of intracellular mRNA localization	P	Any process that modulates the frequency, rate or extent of intracellular mRNA localization.
1904581	negative regulation of intracellular mRNA localization	P	Any process that stops, prevents or reduces the frequency, rate or extent of intracellular mRNA localization.
1904582	positive regulation of intracellular mRNA localization	P	Any process that activates or increases the frequency, rate or extent of intracellular mRNA localization.
1904583	response to polyamine macromolecule	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a polyamine macromolecule stimulus.
1904584	cellular response to polyamine macromolecule	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a polyamine macromolecule stimulus.
1904585	response to putrescine	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a putrescine stimulus.
1904586	cellular response to putrescine	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a putrescine stimulus.
1904587	response to glycoprotein	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glycoprotein stimulus.
1904588	cellular response to glycoprotein	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glycoprotein stimulus.
1904589	regulation of protein import	P	Any process that modulates the frequency, rate or extent of protein import.
1904590	negative regulation of protein import	P	Any process that stops, prevents or reduces the frequency, rate or extent of protein import.
1904591	positive regulation of protein import	P	Any process that activates or increases the frequency, rate or extent of protein import.
1904592	positive regulation of protein refolding	P	Any process that activates or increases the frequency, rate or extent of protein refolding.
1904593	prostaglandin binding	F	Interacting selectively and non-covalently with prostaglandin.
1904594	regulation of termination of RNA polymerase II transcription	P	Any process that modulates the frequency, rate or extent of termination of RNA polymerase II transcription.
1904595	positive regulation of termination of RNA polymerase II transcription	P	Any process that activates or increases the frequency, rate or extent of termination of RNA polymerase II transcription.
1904596	regulation of connective tissue replacement involved in inflammatory response wound healing	P	Any process that modulates the frequency, rate or extent of connective tissue replacement involved in inflammatory response wound healing.
1904597	negative regulation of connective tissue replacement involved in inflammatory response wound healing	P	Any process that stops, prevents or reduces the frequency, rate or extent of connective tissue replacement involved in inflammatory response wound healing.
1904598	positive regulation of connective tissue replacement involved in inflammatory response wound healing	P	Any process that activates or increases the frequency, rate or extent of connective tissue replacement involved in inflammatory response wound healing.
1904599	advanced glycation end-product binding	F	Interacting selectively and non-covalently with advanced glycation end-product.
1904600	actin fusion focus assembly	P	The aggregation, arrangement and bonding together of a set of components to form an actin fusion focus.
1904601	protein localization to actin fusion focus	P	A process in which a protein is transported to, or maintained in, a location within an actin fusion focus.
1904602	serotonin-activated cation-selective channel complex	C	A protein complex which is capable of serotonin-activated cation-selective channel activity. Mainly found in pre- and postsynaptic membranes of the brain and gastrointestinal tract. Depending on its location it transports Ca2+, Mg2+, Na+ or K+. It is always a pentamer, containing at least the 5HT3A subunit forming 5HT3A homopentamers or 5HT3A/B heteropentamers. In human, 5HT3A/C, A/D and A/E heteropentamers also exist.
1904603	regulation of advanced glycation end-product receptor activity	P	Any process that modulates the frequency, rate or extent of advanced glycation end-product receptor activity.
1904604	negative regulation of advanced glycation end-product receptor activity	P	Any process that stops, prevents or reduces the frequency, rate or extent of advanced glycation end-product receptor activity.
1904605	positive regulation of advanced glycation end-product receptor activity	P	Any process that activates or increases the frequency, rate or extent of advanced glycation end-product receptor activity.
1904606	fat cell apoptotic process	P	Any apoptotic process in a fat cell.
1904608	response to monosodium L-glutamate	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a monosodium L-glutamate stimulus.
1904609	cellular response to monosodium L-glutamate	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a monosodium L-glutamate stimulus.
1904610	response to 3,3',4,4',5-pentachlorobiphenyl	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 3,3',4,4',5-pentachlorobiphenyl stimulus.
1904611	cellular response to 3,3',4,4',5-pentachlorobiphenyl	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 3,3',4,4',5-pentachlorobiphenyl stimulus.
1904612	response to 2,3,7,8-tetrachlorodibenzodioxine	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 2,3,7,8-tetrachlorodibenzodioxine stimulus.
1904613	cellular response to 2,3,7,8-tetrachlorodibenzodioxine	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 2,3,7,8-tetrachlorodibenzodioxine stimulus.
1904614	response to biphenyl	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a biphenyl stimulus.
1904615	cellular response to biphenyl	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a biphenyl stimulus.
1904616	regulation of actin binding	P	Any process that modulates the frequency, rate or extent of actin binding.
1904617	negative regulation of actin binding	P	Any process that stops, prevents or reduces the frequency, rate or extent of actin binding.
1904618	positive regulation of actin binding	P	Any process that activates or increases the frequency, rate or extent of actin binding.
1904619	response to dimethyl sulfoxide	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dimethyl sulfoxide stimulus.
1904620	cellular response to dimethyl sulfoxide	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dimethyl sulfoxide stimulus.
1904621	regulation of actin-dependent ATPase activity	P	Any process that modulates the frequency, rate or extent of actin-dependent ATPase activity.
1904622	negative regulation of actin-dependent ATPase activity	P	Any process that stops, prevents or reduces the frequency, rate or extent of actin-dependent ATPase activity.
1904623	positive regulation of actin-dependent ATPase activity	P	Any process that activates or increases the frequency, rate or extent of actin-dependent ATPase activity.
1904624	regulation of glycine secretion, neurotransmission	P	Any process that modulates the frequency, rate or extent of glycine secretion, neurotransmission.
1904625	negative regulation of glycine secretion, neurotransmission	P	Any process that stops, prevents or reduces the frequency, rate or extent of glycine secretion, neurotransmission.
1904626	positive regulation of glycine secretion, neurotransmission	P	Any process that activates or increases the frequency, rate or extent of glycine secretion, neurotransmission.
1904627	response to phorbol 13-acetate 12-myristate	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a phorbol 13-acetate 12-myristate stimulus.
1904628	cellular response to phorbol 13-acetate 12-myristate	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a phorbol 13-acetate 12-myristate stimulus.
1904629	response to diterpene	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diterpene stimulus.
1904630	cellular response to diterpene	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diterpene stimulus.
1904631	response to glucoside	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucoside stimulus.
1904632	cellular response to glucoside	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glucoside stimulus.
1904633	regulation of glomerular visceral epithelial cell apoptotic process	P	Any process that modulates the frequency, rate or extent of glomerular visceral epithelial cell apoptotic process.
1904634	negative regulation of glomerular visceral epithelial cell apoptotic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of glomerular visceral epithelial cell apoptotic process.
1904635	positive regulation of glomerular visceral epithelial cell apoptotic process	P	Any process that activates or increases the frequency, rate or extent of glomerular visceral epithelial cell apoptotic process.
1904636	response to ionomycin	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ionomycin stimulus.
1904637	cellular response to ionomycin	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ionomycin stimulus.
1904638	response to resveratrol	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a resveratrol stimulus.
1904639	cellular response to resveratrol	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a resveratrol stimulus.
1904640	response to methionine	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a methionine stimulus.
1904641	response to dinitrophenol	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dinitrophenol stimulus.
1904642	cellular response to dinitrophenol	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a dinitrophenol stimulus.
1904643	response to curcumin	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a curcumin stimulus.
1904644	cellular response to curcumin	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a curcumin stimulus.
1904645	response to beta-amyloid	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a beta-amyloid stimulus.
1904646	cellular response to beta-amyloid	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a beta-amyloid stimulus.
1904647	response to rotenone	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a rotenone stimulus.
1904648	cellular response to rotenone	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a rotenone stimulus.
1904649	regulation of fat cell apoptotic process	P	Any process that modulates the frequency, rate or extent of fat cell apoptotic process.
1904650	negative regulation of fat cell apoptotic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of fat cell apoptotic process.
1904651	positive regulation of fat cell apoptotic process	P	Any process that activates or increases the frequency, rate or extent of fat cell apoptotic process.
1904652	protein localization to cell division site involved in cell separation after cytokinesis	P	Any protein localization to cell division site that is involved in cell separation after cytokinesis.
1904653	regulation of lung alveolus development	P	Any process that modulates the frequency, rate or extent of lung alveolus development.
1904654	negative regulation of lung alveolus development	P	Any process that stops, prevents or reduces the frequency, rate or extent of lung alveolus development.
1904655	positive regulation of lung alveolus development	P	Any process that activates or increases the frequency, rate or extent of lung alveolus development.
1904656	regulation of sensory perception of sweet taste	P	Any process that modulates the frequency, rate or extent of sensory perception of sweet taste.
1904657	negative regulation of sensory perception of sweet taste	P	Any process that stops, prevents or reduces the frequency, rate or extent of sensory perception of sweet taste.
1904658	positive regulation of sensory perception of sweet taste	P	Any process that activates or increases the frequency, rate or extent of sensory perception of sweet taste.
1904659	glucose transmembrane transport	P	The directed movement of glucose across a membrane.
1904660	regulation of sensory perception of bitter taste	P	Any process that modulates the frequency, rate or extent of sensory perception of bitter taste.
1904661	negative regulation of sensory perception of bitter taste	P	Any process that stops, prevents or reduces the frequency, rate or extent of sensory perception of bitter taste.
1904662	positive regulation of sensory perception of bitter taste	P	Any process that activates or increases the frequency, rate or extent of sensory perception of bitter taste.
1904663	regulation of N-terminal peptidyl-methionine acetylation	P	Any process that modulates the frequency, rate or extent of N-terminal peptidyl-methionine acetylation.
1904664	negative regulation of N-terminal peptidyl-methionine acetylation	P	Any process that stops, prevents or reduces the frequency, rate or extent of N-terminal peptidyl-methionine acetylation.
1904665	positive regulation of N-terminal peptidyl-methionine acetylation	P	Any process that activates or increases the frequency, rate or extent of N-terminal peptidyl-methionine acetylation.
1904666	regulation of ubiquitin protein ligase activity	P	Any process that modulates the frequency, rate or extent of ubiquitin protein ligase activity.
1904667	negative regulation of ubiquitin protein ligase activity	P	Any process that stops, prevents or reduces the frequency, rate or extent of ubiquitin protein ligase activity.
1904668	positive regulation of ubiquitin protein ligase activity	P	Any process that activates or increases the frequency, rate or extent of ubiquitin protein ligase activity.
1904669	ATP export	P	The directed movement of ATP out of a cell or organelle.
1904670	actin filament polymerization involved in mitotic actomyosin contractile ring assembly	P	Any actin filament polymerization that is involved in mitotic actomyosin contractile ring assembly.
1904671	negative regulation of cell differentiation involved in stem cell population maintenance	P	Any negative regulation of cell differentiation that is involved in stem cell population maintenance.
1904672	regulation of somatic stem cell population maintenance	P	Any process that modulates the frequency, rate or extent of somatic stem cell population maintenance.
1904673	negative regulation of somatic stem cell population maintenance	P	Any process that stops, prevents or reduces the frequency, rate or extent of somatic stem cell population maintenance.
1904674	positive regulation of somatic stem cell population maintenance	P	Any process that activates or increases the frequency, rate or extent of somatic stem cell population maintenance.
1904675	regulation of somatic stem cell division	P	Any process that modulates the frequency, rate or extent of somatic stem cell division.
1904676	negative regulation of somatic stem cell division	P	Any process that stops, prevents or reduces the frequency, rate or extent of somatic stem cell division.
1904677	positive regulation of somatic stem cell division	P	Any process that activates or increases the frequency, rate or extent of somatic stem cell division.
1904678	alpha-aminoacyl-tRNA binding	F	Interacting selectively and non-covalently with alpha-aminoacyl-tRNA.
1904679	myo-inositol import across plasma membrane	P	The directed movement of myo-inositol from outside of a cell into the cytoplasmic compartment.
1904680	peptide transmembrane transporter activity	F	Catalysis of the transfer of peptide from one side of the membrane to the other.
1904681	response to 3-methylcholanthrene	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 3-methylcholanthrene stimulus.
1904682	cellular response to 3-methylcholanthrene	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 3-methylcholanthrene stimulus.
1904683	regulation of metalloendopeptidase activity	P	Any process that modulates the frequency, rate or extent of metalloendopeptidase activity.
1904684	negative regulation of metalloendopeptidase activity	P	Any process that stops, prevents or reduces the frequency, rate or extent of metalloendopeptidase activity.
1904685	positive regulation of metalloendopeptidase activity	P	Any process that activates or increases the frequency, rate or extent of metalloendopeptidase activity.
1904686	regulation of mitotic spindle disassembly	P	Any process that modulates the frequency, rate or extent of mitotic spindle disassembly.
1904687	positive regulation of mitotic spindle disassembly	P	Any process that activates or increases the frequency, rate or extent of mitotic spindle disassembly.
1904688	regulation of cytoplasmic translational initiation	P	Any process that modulates the frequency, rate or extent of cytoplasmic translational initiation.
1904689	negative regulation of cytoplasmic translational initiation	P	Any process that stops, prevents or reduces the frequency, rate or extent of cytoplasmic translational initiation.
1904690	positive regulation of cytoplasmic translational initiation	P	Any process that activates or increases the frequency, rate or extent of cytoplasmic translational initiation.
1904691	negative regulation of type B pancreatic cell proliferation	P	Any process that stops, prevents or reduces the frequency, rate or extent of type B pancreatic cell proliferation.
1904692	positive regulation of type B pancreatic cell proliferation	P	Any process that activates or increases the frequency, rate or extent of type B pancreatic cell proliferation.
1904693	midbrain morphogenesis	P	The developmental process by which a midbrain is generated and organized.
1904694	negative regulation of vascular smooth muscle contraction	P	Any process that stops, prevents or reduces the frequency, rate or extent of vascular smooth muscle contraction.
1904695	positive regulation of vascular smooth muscle contraction	P	Any process that activates or increases the frequency, rate or extent of vascular smooth muscle contraction.
1904696	protein localization to cell-cell adherens junction	P	A process in which a protein is transported to, or maintained in, a location within a cell-cell adherens junction.
1904697	regulation of acinar cell proliferation	P	Any process that modulates the frequency, rate or extent of acinar cell proliferation.
1904698	negative regulation of acinar cell proliferation	P	Any process that stops, prevents or reduces the frequency, rate or extent of acinar cell proliferation.
1904699	positive regulation of acinar cell proliferation	P	Any process that activates or increases the frequency, rate or extent of acinar cell proliferation.
1904700	granulosa cell apoptotic process	P	Any apoptotic process in a granulosa cell.
1904701	Wnt-Frizzled-LRP5/6 complex assembly	P	The aggregation, arrangement and bonding together of a set of components to form a Wnt-Frizzled-LRP5/6 complex.
1904702	regulation of protein localization to cell-cell adherens junction	P	Any process that modulates the frequency, rate or extent of protein localization to cell-cell adherens junction.
1904703	negative regulation of protein localization to cell-cell adherens junction	P	Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cell-cell adherens junction.
1904704	positive regulation of protein localization to cell-cell adherens junction	P	Any process that activates or increases the frequency, rate or extent of protein localization to cell-cell adherens junction.
1904705	regulation of vascular smooth muscle cell proliferation	P	Any process that modulates the frequency, rate or extent of vascular smooth muscle cell proliferation.
1904706	negative regulation of vascular smooth muscle cell proliferation	P	Any process that stops, prevents or reduces the frequency, rate or extent of vascular smooth muscle cell proliferation.
1904707	positive regulation of vascular smooth muscle cell proliferation	P	Any process that activates or increases the frequency, rate or extent of vascular smooth muscle cell proliferation.
1904708	regulation of granulosa cell apoptotic process	P	Any process that modulates the frequency, rate or extent of granulosa cell apoptotic process.
1904709	negative regulation of granulosa cell apoptotic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of granulosa cell apoptotic process.
1904710	positive regulation of granulosa cell apoptotic process	P	Any process that activates or increases the frequency, rate or extent of granulosa cell apoptotic process.
1904711	regulation of Wnt-Frizzled-LRP5/6 complex assembly	P	Any process that modulates the frequency, rate or extent of Wnt-Frizzled-LRP5/6 complex assembly.
1904712	positive regulation of Wnt-Frizzled-LRP5/6 complex assembly	P	Any process that activates or increases the frequency, rate or extent of Wnt-Frizzled-LRP5/6 complex assembly.
1904713	beta-catenin destruction complex binding	F	Interacting selectively and non-covalently with a beta-catenin destruction complex.
1904714	regulation of chaperone-mediated autophagy	P	Any process that modulates the frequency, rate or extent of chaperone-mediated autophagy.
1904715	negative regulation of chaperone-mediated autophagy	P	Any process that stops, prevents or reduces the frequency, rate or extent of chaperone-mediated autophagy.
1904716	positive regulation of chaperone-mediated autophagy	P	Any process that activates or increases the frequency, rate or extent of chaperone-mediated autophagy.
1904717	regulation of AMPA glutamate receptor clustering	P	Any process that modulates the frequency, rate or extent of AMPA glutamate receptor clustering.
1904718	negative regulation of AMPA glutamate receptor clustering	P	Any process that stops, prevents or reduces the frequency, rate or extent of AMPA glutamate receptor clustering.
1904719	positive regulation of AMPA glutamate receptor clustering	P	Any process that activates or increases the frequency, rate or extent of AMPA glutamate receptor clustering.
1904720	regulation of mRNA endonucleolytic cleavage involved in unfolded protein response	P	Any process that modulates the frequency, rate or extent of mRNA endonucleolytic cleavage involved in unfolded protein response.
1904721	negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response	P	Any process that stops, prevents or reduces the frequency, rate or extent of mRNA endonucleolytic cleavage involved in unfolded protein response.
1904722	positive regulation of mRNA endonucleolytic cleavage involved in unfolded protein response	P	Any process that activates or increases the frequency, rate or extent of mRNA endonucleolytic cleavage involved in unfolded protein response.
1904723	negative regulation of Wnt-Frizzled-LRP5/6 complex assembly	P	Any process that stops, prevents or reduces the frequency, rate or extent of Wnt-Frizzled-LRP5/6 complex assembly.
1904724	tertiary granule lumen	C	Any membrane-enclosed lumen that is part of a tertiary granule.
1904725	TFIIB-class transcription factor binding involved in negative regulation of transcription	F	Any TFIIB-class transcription factor binding that is involved in negative regulation of DNA-templated transcription.
1904726	regulation of replicative senescence	P	Any process that modulates the frequency, rate or extent of replicative senescence.
1904727	negative regulation of replicative senescence	P	Any process that stops, prevents or reduces the frequency, rate or extent of replicative senescence.
1904728	positive regulation of replicative senescence	P	Any process that activates or increases the frequency, rate or extent of replicative senescence.
1904729	regulation of intestinal lipid absorption	P	Any process that modulates the frequency, rate or extent of intestinal lipid absorption.
1904730	negative regulation of intestinal lipid absorption	P	Any process that stops, prevents or reduces the frequency, rate or extent of intestinal lipid absorption.
1904731	positive regulation of intestinal lipid absorption	P	Any process that activates or increases the frequency, rate or extent of intestinal lipid absorption.
1904732	regulation of electron carrier activity	P	Any process that modulates the frequency, rate or extent of electron carrier activity.
1904733	negative regulation of electron carrier activity	P	Any process that stops, prevents or reduces the frequency, rate or extent of electron carrier activity.
1904734	positive regulation of electron carrier activity	P	Any process that activates or increases the frequency, rate or extent of electron carrier activity.
1904735	regulation of fatty acid beta-oxidation using acyl-CoA dehydrogenase	P	Any process that modulates the frequency, rate or extent of fatty acid beta-oxidation using acyl-CoA dehydrogenase.
1904736	negative regulation of fatty acid beta-oxidation using acyl-CoA dehydrogenase	P	Any process that stops, prevents or reduces the frequency, rate or extent of fatty acid beta-oxidation using acyl-CoA dehydrogenase.
1904737	positive regulation of fatty acid beta-oxidation using acyl-CoA dehydrogenase	P	Any process that activates or increases the frequency, rate or extent of fatty acid beta-oxidation using acyl-CoA dehydrogenase.
1904738	vascular associated smooth muscle cell migration	P	The orderly movement of a vascular associated smooth muscle cell from one site to another.
1904739	regulation of synapse organization by posttranscriptional regulation of gene expression	P	A posttranscriptional regulation of gene expression that results in regulation of synapse organization.
1904740	positive regulation of filamentous growth of a population of unicellular organisms in response to starvation by transcription from RNA polymerase II promoter	P	A transcription from RNA polymerase II promoter that results in positive regulation of filamentous growth of a population of unicellular organisms in response to starvation.
1904741	positive regulation of filamentous growth of a population of unicellular organisms in response to starvation by positive regulation of transcription from RNA polymerase II promoter	P	A positive regulation of transcription from RNA polymerase II promoter that results in positive regulation of filamentous growth of a population of unicellular organisms in response to starvation.
1904742	regulation of telomeric DNA binding	P	Any process that modulates the frequency, rate or extent of telomeric DNA binding.
1904743	negative regulation of telomeric DNA binding	P	Any process that stops, prevents or reduces the frequency, rate or extent of telomeric DNA binding.
1904744	positive regulation of telomeric DNA binding	P	Any process that activates or increases the frequency, rate or extent of telomeric DNA binding.
1904745	ATG1/ULK1 kinase complex assembly	P	The aggregation, arrangement and bonding together of a set of components to form an ATG1/UKL1 kinase complex.
1904746	negative regulation of apoptotic process involved in development	P	Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic process involved in development.
1904747	positive regulation of apoptotic process involved in development	P	Any process that activates or increases the frequency, rate or extent of apoptotic process involved in development.
1904748	regulation of apoptotic process involved in development	P	Any process that modulates the frequency, rate or extent of apoptotic process involved in development.
1904749	regulation of protein localization to nucleolus	P	Any process that modulates the frequency, rate or extent of protein localization to nucleolus.
1904750	negative regulation of protein localization to nucleolus	P	Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to nucleolus.
1904751	positive regulation of protein localization to nucleolus	P	Any process that activates or increases the frequency, rate or extent of protein localization to nucleolus.
1904752	regulation of vascular associated smooth muscle cell migration	P	Any process that modulates the frequency, rate or extent of vascular associated smooth muscle cell migration.
1904753	negative regulation of vascular associated smooth muscle cell migration	P	Any process that stops, prevents or reduces the frequency, rate or extent of vascular associated smooth muscle cell migration.
1904754	positive regulation of vascular associated smooth muscle cell migration	P	Any process that activates or increases the frequency, rate or extent of vascular associated smooth muscle cell migration.
1904755	regulation of gut granule assembly	P	Any process that modulates the frequency, rate or extent of gut granule assembly.
1904756	negative regulation of gut granule assembly	P	Any process that stops, prevents or reduces the frequency, rate or extent of gut granule assembly.
1904757	positive regulation of gut granule assembly	P	Any process that activates or increases the frequency, rate or extent of gut granule assembly.
1904758	protein localization to new growing cell tip	P	A process in which a protein is transported to, or maintained in, a location within a new growing cell tip.
1904759	protein localization to equatorial microtubule organizing center	P	A process in which a protein is transported to, or maintained in, a location within an equatorial microtubule organizing center.
1904760	regulation of myofibroblast differentiation	P	Any process that modulates the frequency, rate or extent of myofibroblast differentiation.
1904761	negative regulation of myofibroblast differentiation	P	Any process that stops, prevents or reduces the frequency, rate or extent of myofibroblast differentiation.
1904762	positive regulation of myofibroblast differentiation	P	Any process that activates or increases the frequency, rate or extent of myofibroblast differentiation.
1904763	chaperone-mediated autophagy translocation complex assembly	P	The aggregation, arrangement and bonding together of a set of components to form a chaperone-mediated autophagy translocation complex.
1904764	chaperone-mediated autophagy translocation complex disassembly	P	The disaggregation of a chaperone-mediated autophagy translocation complex into its constituent components.
1904765	positive regulation of transcription from RNA polymerase II promoter in response to maltose	P	Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a maltose stimulus.
1904766	negative regulation of macroautophagy by TORC1 signaling	P	A TORC1 signaling that results in negative regulation of macroautophagy.
1904767	octanoic acid binding	F	Interacting selectively and non-covalently with octanoic acid.
1904768	all-trans-retinol binding	F	Interacting selectively and non-covalently with all-trans-retinol.
1904769	isopentadecanoic acid binding	F	Interacting selectively and non-covalently with isopentadecanoic acid.
1904770	intramembranous bone morphogenesis	P	The developmental process by which an intramembranous bone is generated and organized.
1904772	response to tetrachloromethane	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a tetrachloromethane stimulus.
1904774	negative regulation of ubiquinone biosynthetic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of ubiquinone biosynthetic process.
1904775	positive regulation of ubiquinone biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of ubiquinone biosynthetic process.
1904776	regulation of protein localization to cell cortex	P	Any process that modulates the frequency, rate or extent of protein localization to cell cortex.
1904777	negative regulation of protein localization to cell cortex	P	Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to cell cortex.
1904778	positive regulation of protein localization to cell cortex	P	Any process that activates or increases the frequency, rate or extent of protein localization to cell cortex.
1904779	regulation of protein localization to centrosome	P	Any process that modulates the frequency, rate or extent of protein localization to centrosome.
1904780	negative regulation of protein localization to centrosome	P	Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to centrosome.
1904781	positive regulation of protein localization to centrosome	P	Any process that activates or increases the frequency, rate or extent of protein localization to centrosome.
1904782	negative regulation of NMDA glutamate receptor activity	P	Any process that stops, prevents or reduces the frequency, rate or extent of NMDA glutamate receptor activity.
1904783	positive regulation of NMDA glutamate receptor activity	P	Any process that activates or increases the frequency, rate or extent of NMDA glutamate receptor activity.
1904784	NLRP1 inflammasome complex assembly	P	The aggregation, arrangement and bonding together of a set of components to form a NLRP1 inflammasome complex.
1904785	regulation of asymmetric protein localization involved in cell fate determination	P	Any process that modulates the frequency, rate or extent of asymmetric protein localization involved in cell fate determination.
1904786	negative regulation of asymmetric protein localization involved in cell fate determination	P	Any process that stops, prevents or reduces the frequency, rate or extent of asymmetric protein localization involved in cell fate determination.
1904787	positive regulation of asymmetric protein localization involved in cell fate determination	P	Any process that activates or increases the frequency, rate or extent of asymmetric protein localization involved in cell fate determination.
1904788	positive regulation of induction of conjugation with cellular fusion by regulation of transcription from RNA polymerase II promoter	P	A regulation of transcription from RNA polymerase II promoter that results in positive regulation of induction of conjugation with cellular fusion.
1904789	regulation of mitotic actomyosin contractile ring maintenance	P	Any process that modulates the frequency, rate or extent of mitotic actomyosin contractile ring maintenance.
1904790	regulation of telosome assembly	P	Any process that modulates the frequency, rate or extent of telosome assembly.
1904791	negative regulation of telosome assembly	P	Any process that stops, prevents or reduces the frequency, rate or extent of telosome assembly.
1904792	positive regulation of telosome assembly	P	Any process that activates or increases the frequency, rate or extent of telosome assembly.
1904793	regulation of euchromatin binding	P	Any process that modulates the frequency, rate or extent of euchromatin binding.
1904794	negative regulation of euchromatin binding	P	Any process that stops, prevents or reduces the frequency, rate or extent of euchromatin binding.
1904795	positive regulation of euchromatin binding	P	Any process that activates or increases the frequency, rate or extent of euchromatin binding.
1904796	regulation of core promoter binding	P	Any process that modulates the frequency, rate or extent of core promoter binding.
1904797	negative regulation of core promoter binding	P	Any process that stops, prevents or reduces the frequency, rate or extent of core promoter binding.
1904798	positive regulation of core promoter binding	P	Any process that activates or increases the frequency, rate or extent of core promoter binding.
1904799	regulation of neuron remodeling	P	Any process that modulates the frequency, rate or extent of neuron remodeling.
1904800	negative regulation of neuron remodeling	P	Any process that stops, prevents or reduces the frequency, rate or extent of neuron remodeling.
1904801	positive regulation of neuron remodeling	P	Any process that activates or increases the frequency, rate or extent of neuron remodeling.
1904802	RITS complex assembly	P	The aggregation, arrangement and bonding together of a set of components to form a RITS complex.
1904803	regulation of translation involved in cellular response to UV	P	Any regulation of translation that is involved in cellular response to UV.
1904804	response to latrunculin A	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a latrunculin A stimulus.
1904805	cellular response to latrunculin A	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a latrunculin A stimulus.
1904806	regulation of protein oxidation	P	Any process that modulates the frequency, rate or extent of protein oxidation.
1904807	negative regulation of protein oxidation	P	Any process that stops, prevents or reduces the frequency, rate or extent of protein oxidation.
1904808	positive regulation of protein oxidation	P	Any process that activates or increases the frequency, rate or extent of protein oxidation.
1904809	regulation of dense core granule transport	P	Any process that modulates the frequency, rate or extent of dense core granule transport.
1904810	negative regulation of dense core granule transport	P	Any process that stops, prevents or reduces the frequency, rate or extent of dense core granule transport.
1904811	positive regulation of dense core granule transport	P	Any process that activates or increases the frequency, rate or extent of dense core granule transport.
1904812	rRNA acetylation involved in maturation of SSU-rRNA	P	Any rRNA acetylation that is involved in maturation of SSU-rRNA.
1904813	ficolin-1-rich granule lumen	C	Any membrane-enclosed lumen that is part of a ficolin-1-rich granule.
1904814	regulation of protein localization to chromosome, telomeric region	P	Any process that modulates the frequency, rate or extent of protein localization to chromosome, telomeric region.
1904815	negative regulation of protein localization to chromosome, telomeric region	P	Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to chromosome, telomeric region.
1904816	positive regulation of protein localization to chromosome, telomeric region	P	Any process that activates or increases the frequency, rate or extent of protein localization to chromosome, telomeric region.
1904817	serous membrane development	P	The process whose specific outcome is the progression of a serous membrane over time, from its formation to the mature structure.
1904818	visceral peritoneum development	P	The process whose specific outcome is the progression of a visceral peritoneum over time, from its formation to the mature structure.
1904819	parietal peritoneum development	P	The process whose specific outcome is the progression of a parietal peritoneum over time, from its formation to the mature structure.
1904820	peritoneum development	P	The process whose specific outcome is the progression of a peritoneum over time, from its formation to the mature structure.
1904821	chloroplast disassembly	P	The disaggregation of a chloroplast into its constituent components.
1904822	ubiquitin protein ligase activity involved in chloroplast disassembly	F	Any ubiquitin protein ligase activity that is involved in chloroplast disassembly.
1904823	purine nucleobase transmembrane transport	P	The directed movement of purine nucleobase across a membrane.
1904824	anaphase-promoting complex assembly	P	The aggregation, arrangement and bonding together of a set of components to form an anaphase-promoting complex.
1904825	protein localization to microtubule plus-end	P	A process in which a protein is transported to, or maintained in, a location at a microtubule plus-end.
1904826	regulation of hydrogen sulfide biosynthetic process	P	Any process that modulates the frequency, rate or extent of hydrogen sulfide biosynthetic process.
1904827	negative regulation of hydrogen sulfide biosynthetic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of hydrogen sulfide biosynthetic process.
1904828	positive regulation of hydrogen sulfide biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of hydrogen sulfide biosynthetic process.
1904829	regulation of aortic smooth muscle cell differentiation	P	Any process that modulates the frequency, rate or extent of aortic smooth muscle cell differentiation.
1904830	negative regulation of aortic smooth muscle cell differentiation	P	Any process that stops, prevents or reduces the frequency, rate or extent of aortic smooth muscle cell differentiation.
1904831	positive regulation of aortic smooth muscle cell differentiation	P	Any process that activates or increases the frequency, rate or extent of aortic smooth muscle cell differentiation.
1904832	negative regulation of removal of superoxide radicals	P	Any process that stops, prevents or reduces the frequency, rate or extent of removal of superoxide radicals.
1904833	positive regulation of removal of superoxide radicals	P	Any process that activates or increases the frequency, rate or extent of removal of superoxide radicals.
1904834	nuclear CENP-A containing chromatin	C	Any CENP-A containing chromatin that is part of nuclear chromatin.
1904835	dorsal root ganglion morphogenesis	P	The developmental process by which a dorsal root ganglion is generated and organized.
1904836	facioacoustic ganglion morphogenesis	P	The developmental process by which an acoustico-facial VII-VIII ganglion complex is generated and organized.
1904837	beta-catenin-TCF complex assembly	P	The aggregation, arrangement and bonding together of a set of components to form a beta-catenin-TCF complex.
1904838	regulation of male germ-line stem cell asymmetric division	P	Any process that modulates the frequency, rate or extent of male germ-line stem cell asymmetric division.
1904839	negative regulation of male germ-line stem cell asymmetric division	P	Any process that stops, prevents or reduces the frequency, rate or extent of male germ-line stem cell asymmetric division.
1904840	positive regulation of male germ-line stem cell asymmetric division	P	Any process that activates or increases the frequency, rate or extent of male germ-line stem cell asymmetric division.
1904841	TORC2 complex binding	F	Interacting selectively and non-covalently with a TORC2 complex.
1904842	response to nitroglycerin	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitroglycerin stimulus.
1904843	cellular response to nitroglycerin	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitroglycerin stimulus.
1904844	response to L-glutamine	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-glutamine stimulus.
1904845	cellular response to L-glutamine	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-glutamine stimulus.
1904846	negative regulation of establishment of bipolar cell polarity	P	Any process that stops, prevents or reduces the frequency, rate or extent of establishment of bipolar cell polarity.
1904847	regulation of cell chemotaxis to fibroblast growth factor	P	Any process that modulates the frequency, rate or extent of cell chemotaxis to fibroblast growth factor.
1904848	negative regulation of cell chemotaxis to fibroblast growth factor	P	Any process that stops, prevents or reduces the frequency, rate or extent of cell chemotaxis to fibroblast growth factor.
1904849	positive regulation of cell chemotaxis to fibroblast growth factor	P	Any process that activates or increases the frequency, rate or extent of cell chemotaxis to fibroblast growth factor.
1904850	negative regulation of establishment of protein localization to telomere	P	Any process that stops, prevents or reduces the frequency, rate or extent of establishment of protein localization to telomere.
1904851	positive regulation of establishment of protein localization to telomere	P	Any process that activates or increases the frequency, rate or extent of establishment of protein localization to telomere.
1904852	trimethylamine-N-oxide reductase (cytochrome c) complex	C	A protein complex which is capable of trimethylamine-N-oxide reductase (cytochrome c) activity.
1904853	protein localization to ascospore wall	P	A process in which a protein is transported to, or maintained in, a location within an ascospore wall.
1904854	proteasome core complex binding	F	Interacting selectively and non-covalently with a proteasome core complex.
1904855	proteasome regulatory particle binding	F	Interacting selectively and non-covalently with a proteasome regulatory particle.
1904856	cytolytic granule lumen	C	Any cytoplasmic membrane-bounded vesicle lumen that is part of a cytolytic granule.
1904857	regulation of endothelial cell chemotaxis to vascular endothelial growth factor	P	Any process that modulates the frequency, rate or extent of endothelial cell chemotaxis to vascular endothelial growth factor.
1904858	negative regulation of endothelial cell chemotaxis to vascular endothelial growth factor	P	Any process that stops, prevents or reduces the frequency, rate or extent of endothelial cell chemotaxis to vascular endothelial growth factor.
1904859	positive regulation of endothelial cell chemotaxis to vascular endothelial growth factor	P	Any process that activates or increases the frequency, rate or extent of endothelial cell chemotaxis to vascular endothelial growth factor.
1904860	DNA biosynthetic process involved in mitotic DNA replication	P	Any DNA biosynthetic process that is involved in mitotic DNA replication.
1904861	excitatory synapse assembly	P	The aggregation, arrangement and bonding together of a set of components to form an excitatory synapse.
1904862	inhibitory synapse assembly	P	The aggregation, arrangement and bonding together of a set of components to form an inhibitory synapse.
1904863	regulation of beta-catenin-TCF complex assembly	P	Any process that modulates the frequency, rate or extent of beta-catenin-TCF complex assembly.
1904864	negative regulation of beta-catenin-TCF complex assembly	P	Any process that stops, prevents or reduces the frequency, rate or extent of beta-catenin-TCF complex assembly.
1904865	positive regulation of beta-catenin-TCF complex assembly	P	Any process that activates or increases the frequency, rate or extent of beta-catenin-TCF complex assembly.
1904866	ventral tegmental area development	P	The process whose specific outcome is the progression of a ventral tegmental area (VTA) over time, from its formation to the mature structure.
1904867	protein localization to Cajal body	P	A process in which a protein is transported to, or maintained in, a location within a Cajal body.
1904868	telomerase catalytic core complex assembly	P	The aggregation, arrangement and bonding together of a set of components to form a telomerase catalytic core complex.
1904869	regulation of protein localization to Cajal body	P	Any process that modulates the frequency, rate or extent of protein localization to Cajal body.
1904870	negative regulation of protein localization to Cajal body	P	Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to Cajal body.
1904871	positive regulation of protein localization to Cajal body	P	Any process that activates or increases the frequency, rate or extent of protein localization to Cajal body.
1904872	regulation of telomerase RNA localization to Cajal body	P	Any process that modulates the frequency, rate or extent of telomerase RNA localization to Cajal body.
1904873	negative regulation of telomerase RNA localization to Cajal body	P	Any process that stops, prevents or reduces the frequency, rate or extent of telomerase RNA localization to Cajal body.
1904874	positive regulation of telomerase RNA localization to Cajal body	P	Any process that activates or increases the frequency, rate or extent of telomerase RNA localization to Cajal body.
1904875	regulation of DNA ligase activity	P	Any process that modulates the frequency, rate or extent of DNA ligase activity.
1904876	negative regulation of DNA ligase activity	P	Any process that stops, prevents or reduces the frequency, rate or extent of DNA ligase activity.
1904877	positive regulation of DNA ligase activity	P	Any process that activates or increases the frequency, rate or extent of DNA ligase activity.
1904878	negative regulation of calcium ion transmembrane transport via high voltage-gated calcium channel	P	Any process that stops, prevents or reduces the frequency, rate or extent of calcium ion transmembrane transport via high voltage-gated calcium channel.
1904879	positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel	P	Any process that activates or increases the frequency, rate or extent of calcium ion transmembrane transport via high voltage-gated calcium channel.
1904880	response to hydrogen sulfide	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrogen sulfide stimulus.
1904881	cellular response to hydrogen sulfide	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrogen sulfide stimulus.
1904882	regulation of telomerase catalytic core complex assembly	P	Any process that modulates the frequency, rate or extent of telomerase catalytic core complex assembly.
1904883	negative regulation of telomerase catalytic core complex assembly	P	Any process that stops, prevents or reduces the frequency, rate or extent of telomerase catalytic core complex assembly.
1904884	positive regulation of telomerase catalytic core complex assembly	P	Any process that activates or increases the frequency, rate or extent of telomerase catalytic core complex assembly.
1904885	beta-catenin destruction complex assembly	P	The aggregation, arrangement and bonding together of a set of components to form a beta-catenin destruction complex.
1904886	beta-catenin destruction complex disassembly	P	The disaggregation of a beta-catenin destruction complex into its constituent components.
1904887	Wnt signalosome assembly	P	The aggregation, arrangement and bonding together of a set of components to form a Wnt signalosome.
1904888	cranial skeletal system development	P	The process whose specific outcome is the progression of a cranial skeletal system over time, from its formation to the mature structure. The cranial skeletal system is the skeletal subdivision of the head, and includes the skull (cranium plus mandible), pharyngeal and/or hyoid apparatus.
1904889	regulation of excitatory synapse assembly	P	Any process that modulates the frequency, rate or extent of excitatory synapse assembly.
1904890	negative regulation of excitatory synapse assembly	P	Any process that stops, prevents or reduces the frequency, rate or extent of excitatory synapse assembly.
1904891	positive regulation of excitatory synapse assembly	P	Any process that activates or increases the frequency, rate or extent of excitatory synapse assembly.
1904892	regulation of STAT cascade	P	Any process that modulates the frequency, rate or extent of STAT cascade.
1904893	negative regulation of STAT cascade	P	Any process that stops, prevents or reduces the frequency, rate or extent of STAT cascade.
1904894	positive regulation of STAT cascade	P	Any process that activates or increases the frequency, rate or extent of STAT cascade.
1904895	ESCRT complex assembly	P	The aggregation, arrangement and bonding together of a set of components to form an ESCRT complex.
1904896	ESCRT complex disassembly	P	The disaggregation of an ESCRT complex into its constituent components.
1904897	regulation of hepatic stellate cell proliferation	P	Any process that modulates the frequency, rate or extent of hepatic stellate cell proliferation.
1904898	negative regulation of hepatic stellate cell proliferation	P	Any process that stops, prevents or reduces the frequency, rate or extent of hepatic stellate cell proliferation.
1904899	positive regulation of hepatic stellate cell proliferation	P	Any process that activates or increases the frequency, rate or extent of hepatic stellate cell proliferation.
1904900	negative regulation of myosin II filament organization	P	Any process that stops, prevents or reduces the frequency, rate or extent of myosin II filament organization.
1904901	positive regulation of myosin II filament organization	P	Any process that activates or increases the frequency, rate or extent of myosin II filament organization.
1904902	ESCRT III complex assembly	P	The aggregation, arrangement and bonding together of a set of components to form an ESCRT III complex.
1904903	ESCRT III complex disassembly	P	The disaggregation of an ESCRT III complex into its constituent components.
1904904	regulation of endothelial cell-matrix adhesion via fibronectin	P	Any process that modulates the frequency, rate or extent of endothelial cell-matrix adhesion via fibronectin.
1904905	negative regulation of endothelial cell-matrix adhesion via fibronectin	P	Any process that stops, prevents or reduces the frequency, rate or extent of endothelial cell-matrix adhesion via fibronectin.
1904906	positive regulation of endothelial cell-matrix adhesion via fibronectin	P	Any process that activates or increases the frequency, rate or extent of endothelial cell-matrix adhesion via fibronectin.
1904907	regulation of maintenance of mitotic sister chromatid cohesion, telomeric	P	Any process that modulates the frequency, rate or extent of maintenance of mitotic sister chromatid cohesion, telomeric.
1904908	negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric	P	Any process that stops, prevents or reduces the frequency, rate or extent of maintenance of mitotic sister chromatid cohesion, telomeric.
1904909	positive regulation of maintenance of mitotic sister chromatid cohesion, telomeric	P	Any process that activates or increases the frequency, rate or extent of maintenance of mitotic sister chromatid cohesion, telomeric.
1904910	regulation of establishment of RNA localization to telomere	P	Any process that modulates the frequency, rate or extent of establishment of RNA localization to telomere.
1904911	negative regulation of establishment of RNA localization to telomere	P	Any process that stops, prevents or reduces the frequency, rate or extent of establishment of RNA localization to telomere.
1904912	positive regulation of establishment of RNA localization to telomere	P	Any process that activates or increases the frequency, rate or extent of establishment of RNA localization to telomere.
1904913	regulation of establishment of macromolecular complex localization to telomere	P	Any process that modulates the frequency, rate or extent of establishment of macromolecular complex localization to telomere.
1904914	negative regulation of establishment of macromolecular complex localization to telomere	P	Any process that stops, prevents or reduces the frequency, rate or extent of establishment of macromolecular complex localization to telomere.
1904915	positive regulation of establishment of macromolecular complex localization to telomere	P	Any process that activates or increases the frequency, rate or extent of establishment of macromolecular complex localization to telomere.
1904916	transmembrane L-lysine transport from lysosomal lumen to cytosol	P	The directed movement of L-lysine across a membrane from lysosomal lumen to cytosol.
1904917	transmembrane L-arginine transport from lysosomal lumen to cytosol	P	The directed movement of L-arginine across a membrane from lysosomal lumen to cytosol.
1904918	transmembrane L-histidine transport from lysosomal lumen to cytosol	P	The directed movement of L-histidine across a membrane from lysosomal lumen to cytosol.
1904919	transmembrane L-cystine transport from lysosomal lumen to cytosol	P	The directed movement of L-cystine across a membrane from lysosomal lumen to cytosol.
1904920	regulation of MAPK cascade involved in axon regeneration	P	Any process that modulates the frequency, rate or extent of MAPK cascade involved in axon regeneration.
1904921	negative regulation of MAPK cascade involved in axon regeneration	P	Any process that stops, prevents or reduces the frequency, rate or extent of MAPK cascade involved in axon regeneration.
1904922	positive regulation of MAPK cascade involved in axon regeneration	P	Any process that activates or increases the frequency, rate or extent of MAPK cascade involved in axon regeneration.
1904923	regulation of mitophagy in response to mitochondrial depolarization	P	Any process that modulates the frequency, rate or extent of mitophagy in response to mitochondrial depolarization.
1904924	negative regulation of mitophagy in response to mitochondrial depolarization	P	Any process that stops, prevents or reduces the frequency, rate or extent of mitophagy in response to mitochondrial depolarization.
1904925	positive regulation of mitophagy in response to mitochondrial depolarization	P	Any process that activates or increases the frequency, rate or extent of mitophagy in response to mitochondrial depolarization.
1904926	response to palmitoleic acid	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a palmitoleic acid stimulus.
1904927	cellular response to palmitoleic acid	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a palmitoleic acid stimulus.
1904928	coreceptor activity involved in canonical Wnt signaling pathway	F	Any coreceptor activity that is involved in a canonical Wnt signaling pathway.
1904929	coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway	F	Any coreceptor activity that is involved in Wnt signaling pathway, planar cell polarity pathway.
1904930	amphisome membrane	C	Any membrane that is part of an amphisome.
1904931	MCM complex binding	F	Interacting selectively and non-covalently with an MCM complex.
1904932	negative regulation of cartilage condensation	P	Any process that stops, prevents or reduces the frequency, rate or extent of cartilage condensation.
1904933	regulation of cell proliferation in midbrain	P	Any process that modulates the frequency, rate or extent of cell proliferation in midbrain.
1904934	negative regulation of cell proliferation in midbrain	P	Any process that stops, prevents or reduces the frequency, rate or extent of cell proliferation in midbrain.
1904935	positive regulation of cell proliferation in midbrain	P	Any process that activates or increases the frequency, rate or extent of cell proliferation in midbrain.
1904936	interneuron migration	P	The orderly movement of an interneuron from one site to another.
1904937	sensory neuron migration	P	The orderly movement of a sensory neuron from one site to another.
1904938	planar cell polarity pathway involved in axon guidance	P	Any Wnt signaling pathway, planar cell polarity pathway that is involved in axon guidance.
1904939	regulation of DNA nucleotidylexotransferase activity	P	Any process that modulates the frequency, rate or extent of DNA nucleotidylexotransferase activity.
1904940	negative regulation of DNA nucleotidylexotransferase activity	P	Any process that stops, prevents or reduces the frequency, rate or extent of DNA nucleotidylexotransferase activity.
1904941	positive regulation of DNA nucleotidylexotransferase activity	P	Any process that activates or increases the frequency, rate or extent of DNA nucleotidylexotransferase activity.
1904942	regulation of cardiac ventricle formation	P	Any process that modulates the frequency, rate or extent of cardiac ventricle formation.
1904943	negative regulation of cardiac ventricle formation	P	Any process that stops, prevents or reduces the frequency, rate or extent of cardiac ventricle formation.
1904944	positive regulation of cardiac ventricle formation	P	Any process that activates or increases the frequency, rate or extent of cardiac ventricle formation.
1904947	folic acid import into mitochondrion	P	The directed movement of folic acid into a mitochondrion.
1904948	midbrain dopaminergic neuron differentiation	P	The process in which a relatively unspecialized cell acquires the specialized features of a midbrain dopaminergic neuron.
1904949	ATPase complex	C	A protein complex which is capable of ATPase activity.
1904950	negative regulation of establishment of protein localization	P	Any process that stops, prevents or reduces the frequency, rate or extent of establishment of protein localization.
1904951	positive regulation of establishment of protein localization	P	Any process that activates or increases the frequency, rate or extent of establishment of protein localization.
1904952	hydroxycinnamic acid transport	P	The directed movement of a hydroxycinnamic acid into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
1904953	Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation	P	Any Wnt signaling pathway that is involved in midbrain dopaminergic neuron differentiation.
1904954	canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation	P	Any canonical Wnt signaling pathway that is involved in midbrain dopaminergic neuron differentiation.
1904955	planar cell polarity pathway involved in midbrain dopaminergic neuron differentiation	P	Any Wnt signaling pathway, planar cell polarity pathway that is involved in midbrain dopaminergic neuron differentiation.
1904956	regulation of midbrain dopaminergic neuron differentiation	P	Any process that modulates the frequency, rate or extent of midbrain dopaminergic neuron differentiation.
1904957	negative regulation of midbrain dopaminergic neuron differentiation	P	Any process that stops, prevents or reduces the frequency, rate or extent of midbrain dopaminergic neuron differentiation.
1904958	positive regulation of midbrain dopaminergic neuron differentiation	P	Any process that activates or increases the frequency, rate or extent of midbrain dopaminergic neuron differentiation.
1904959	regulation of cytochrome-c oxidase activity	P	Any process that modulates the frequency, rate or extent of cytochrome-c oxidase activity.
1904960	positive regulation of cytochrome-c oxidase activity	P	Any process that activates or increases the frequency, rate or extent of cytochrome-c oxidase activity.
1904961	quiescent center organization	P	The process that contributes to the act of creating the structural organization of the quiescent center. This process pertains to the physical shaping of a rudimentary structure.
1904962	plastid to vacuole vesicle-mediated transport	P	The vesicle-mediated and directed movement of substances from plastid to vacuole.
1904963	regulation of phytol biosynthetic process	P	Any process that modulates the frequency, rate or extent of phytol biosynthetic process.
1904964	positive regulation of phytol biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of phytol biosynthetic process.
1904965	regulation of vitamin E biosynthetic process	P	Any process that modulates the frequency, rate or extent of vitamin E biosynthetic process.
1904966	positive regulation of vitamin E biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of vitamin E biosynthetic process.
1904967	regulation of attachment of spindle microtubules to kinetochore involved in homologous chromosome segregation	P	Any process that modulates the frequency, rate or extent of attachment of spindle microtubules to kinetochore involved in homologous chromosome segregation.
1904968	positive regulation of attachment of spindle microtubules to kinetochore involved in homologous chromosome segregation	P	Any process that activates or increases the frequency, rate or extent of attachment of spindle microtubules to kinetochore involved in homologous chromosome segregation.
1904969	slow muscle cell migration	P	The orderly movement of a slow muscle cell from one site to another.
1904970	brush border assembly	P	The aggregation, arrangement and bonding together of adjacent microvilli through the formation of Ca(2+)-dependent adhesion links between them, forming a brush border.
1904971	regulation of viral translation	P	Any process that modulates the frequency, rate or extent of viral translation.
1904972	negative regulation of viral translation	P	Any process that stops, prevents or reduces the frequency, rate or extent of viral translation.
1904973	positive regulation of viral translation	P	Any process that activates or increases the frequency, rate or extent of viral translation.
1904974	heparanase complex	C	A protein complex which is capable of heparanase activity.
1904975	response to bleomycin	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bleomycin stimulus.
1904976	cellular response to bleomycin	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a bleomycin stimulus.
1904977	lymphatic endothelial cell migration	P	The orderly movement of a lymphatic endothelial cell from one site to another in the wall of a lymphatic vessel.
1904978	regulation of endosome organization	P	Any process that modulates the frequency, rate or extent of endosome organization.
1904979	negative regulation of endosome organization	P	Any process that stops, prevents or reduces the frequency, rate or extent of endosome organization.
1904980	positive regulation of endosome organization	P	Any process that activates or increases the frequency, rate or extent of endosome organization.
1904981	maltose transmembrane transport	P	The directed movement of maltose across a membrane.
1904982	sucrose transmembrane transport	P	The directed movement of sucrose across a membrane.
1904983	transmembrane glycine transport from cytosol to mitochondrion	P	The directed movement of glycine across a membrane from cytosol to mitochondrion.
1904984	regulation of quinolinate biosynthetic process	P	Any process that modulates the frequency, rate or extent of quinolinate biosynthetic process.
1904985	negative regulation of quinolinate biosynthetic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of quinolinate biosynthetic process.
1904986	positive regulation of quinolinate biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of quinolinate biosynthetic process.
1904987	regulation of endothelial cell activation	P	Any process that modulates the frequency, rate or extent of endothelial cell activation.
1904988	negative regulation of endothelial cell activation	P	Any process that stops, prevents or reduces the frequency, rate or extent of endothelial cell activation.
1904989	positive regulation of endothelial cell activation	P	Any process that activates or increases the frequency, rate or extent of endothelial cell activation.
1904990	regulation of adenylate cyclase-inhibiting dopamine receptor signaling pathway	P	Any process that modulates the frequency, rate or extent of adenylate cyclase-inhibiting dopamine receptor signaling pathway.
1904991	negative regulation of adenylate cyclase-inhibiting dopamine receptor signaling pathway	P	Any process that stops, prevents or reduces the frequency, rate or extent of adenylate cyclase-inhibiting dopamine receptor signaling pathway.
1904992	positive regulation of adenylate cyclase-inhibiting dopamine receptor signaling pathway	P	Any process that activates or increases the frequency, rate or extent of adenylate cyclase-inhibiting dopamine receptor signaling pathway.
1904994	regulation of leukocyte adhesion to vascular endothelial cell	P	Any process that modulates the frequency, rate or extent of leukocyte adhesion to vascular endothelial cell.
1904995	negative regulation of leukocyte adhesion to vascular endothelial cell	P	Any process that stops, prevents or reduces the frequency, rate or extent of leukocyte adhesion to vascular endothelial cell.
1904996	positive regulation of leukocyte adhesion to vascular endothelial cell	P	Any process that activates or increases the frequency, rate or extent of leukocyte adhesion to vascular endothelial cell.
1904997	regulation of leukocyte adhesion to arterial endothelial cell	P	Any process that modulates the frequency, rate or extent of leukocyte adhesion to arterial endothelial cell.
1904998	negative regulation of leukocyte adhesion to arterial endothelial cell	P	Any process that stops, prevents or reduces the frequency, rate or extent of leukocyte adhesion to arterial endothelial cell.
1904999	positive regulation of leukocyte adhesion to arterial endothelial cell	P	Any process that activates or increases the frequency, rate or extent of leukocyte adhesion to arterial endothelial cell.
1905000	regulation of membrane repolarization during atrial cardiac muscle cell action potential	P	Any process that modulates the frequency, rate or extent of membrane repolarization during atrial cardiac muscle cell action potential.
1905001	negative regulation of membrane repolarization during atrial cardiac muscle cell action potential	P	Any process that stops, prevents or reduces the frequency, rate or extent of membrane repolarization during atrial cardiac muscle cell action potential.
1905002	positive regulation of membrane repolarization during atrial cardiac muscle cell action potential	P	Any process that activates or increases the frequency, rate or extent of membrane repolarization during atrial cardiac muscle cell action potential.
1905003	picolinic acid metabolic process	P	The chemical reactions and pathways involving picolinic acid.
1905004	picolinic acid biosynthetic process	P	The chemical reactions and pathways resulting in the formation of picolinic acid.
1905005	regulation of epithelial to mesenchymal transition involved in endocardial cushion formation	P	Any process that modulates the frequency, rate or extent of epithelial to mesenchymal transition involved in endocardial cushion formation.
1905006	negative regulation of epithelial to mesenchymal transition involved in endocardial cushion formation	P	Any process that stops, prevents or reduces the frequency, rate or extent of epithelial to mesenchymal transition involved in endocardial cushion formation.
1905007	positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation	P	Any process that activates or increases the frequency, rate or extent of epithelial to mesenchymal transition involved in endocardial cushion formation.
1905008	regulation of L-lysine import into cell	P	Any process that modulates the frequency, rate or extent of L-lysine import into cell.
1905009	negative regulation of L-lysine import into cell	P	Any process that stops, prevents or reduces the frequency, rate or extent of L-lysine import into cell.
1905010	positive regulation of L-lysine import into cell	P	Any process that activates or increases the frequency, rate or extent of L-lysine import into cell.
1905011	transmembrane phosphate ion transport from cytosol to vacuole	P	The directed movement of phosphate ions across a membrane from the cytosol into a vacuole.
1905012	regulation of 'de novo' NAD biosynthetic process from tryptophan	P	Any process that modulates the frequency, rate or extent of 'de novo' NAD biosynthetic process from tryptophan.
1905013	negative regulation of 'de novo' NAD biosynthetic process from tryptophan	P	Any process that stops, prevents or reduces the frequency, rate or extent of 'de novo' NAD biosynthetic process from tryptophan.
1905014	positive regulation of 'de novo' NAD biosynthetic process from tryptophan	P	Any process that activates or increases the frequency, rate or extent of 'de novo' NAD biosynthetic process from tryptophan.
1905015	regulation of isoleucine-tRNA ligase activity	P	Any process that modulates the frequency, rate or extent of isoleucine-tRNA ligase activity.
1905016	negative regulation of isoleucine-tRNA ligase activity	P	Any process that stops, prevents or reduces the frequency, rate or extent of isoleucine-tRNA ligase activity.
1905017	positive regulation of isoleucine-tRNA ligase activity	P	Any process that activates or increases the frequency, rate or extent of isoleucine-tRNA ligase activity.
1905018	regulation of methionine-tRNA ligase activity	P	Any process that modulates the frequency, rate or extent of methionine-tRNA ligase activity.
1905019	negative regulation of methionine-tRNA ligase activity	P	Any process that stops, prevents or reduces the frequency, rate or extent of methionine-tRNA ligase activity.
1905020	positive regulation of methionine-tRNA ligase activity	P	Any process that activates or increases the frequency, rate or extent of methionine-tRNA ligase activity.
1905021	regulation of threonine-tRNA ligase activity	P	Any process that modulates the frequency, rate or extent of threonine-tRNA ligase activity.
1905022	negative regulation of threonine-tRNA ligase activity	P	Any process that stops, prevents or reduces the frequency, rate or extent of threonine-tRNA ligase activity.
1905023	positive regulation of threonine-tRNA ligase activity	P	Any process that activates or increases the frequency, rate or extent of threonine-tRNA ligase activity.
1905024	regulation of membrane repolarization during ventricular cardiac muscle cell action potential	P	Any process that modulates the frequency, rate or extent of membrane repolarization during ventricular cardiac muscle cell action potential.
1905025	negative regulation of membrane repolarization during ventricular cardiac muscle cell action potential	P	Any process that stops, prevents or reduces the frequency, rate or extent of membrane repolarization during ventricular cardiac muscle cell action potential.
1905026	positive regulation of membrane repolarization during ventricular cardiac muscle cell action potential	P	Any process that activates or increases the frequency, rate or extent of membrane repolarization during ventricular cardiac muscle cell action potential.
1905027	regulation of membrane depolarization during AV node cell action potential	P	Any process that modulates the frequency, rate or extent of membrane depolarization during AV node cell action potential.
1905028	negative regulation of membrane depolarization during AV node cell action potential	P	Any process that stops, prevents or reduces the frequency, rate or extent of membrane depolarization during AV node cell action potential.
1905029	positive regulation of membrane depolarization during AV node cell action potential	P	Any process that activates or increases the frequency, rate or extent of membrane depolarization during AV node cell action potential.
1905030	voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential	F	Any voltage-gated ion channel activity that is involved in regulation of postsynaptic membrane potential.
1905031	regulation of membrane repolarization during cardiac muscle cell action potential	P	Any process that modulates the frequency, rate or extent of membrane repolarization during cardiac muscle cell action potential.
1905032	negative regulation of membrane repolarization during cardiac muscle cell action potential	P	Any process that stops, prevents or reduces the frequency, rate or extent of membrane repolarization during cardiac muscle cell action potential.
1905033	positive regulation of membrane repolarization during cardiac muscle cell action potential	P	Any process that activates or increases the frequency, rate or extent of membrane repolarization during cardiac muscle cell action potential.
1905034	regulation of antifungal innate immune response	P	Any process that modulates the frequency, rate or extent of an antifungal innate immune response.
1905035	negative regulation of antifungal innate immune response	P	Any process that stops, prevents or reduces the frequency, rate or extent of an antifungal innate immune response.
1905036	positive regulation of antifungal innate immune response	P	Any process that activates or increases the frequency, rate or extent of an antifungal innate immune response.
1905037	autophagosome organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of an autophagosome.
1905038	regulation of membrane lipid metabolic process	P	Any process that modulates the frequency, rate or extent of membrane lipid metabolic process.
1905039	carboxylic acid transmembrane transport	P	The directed movement of carboxylic acid across a membrane.
1905040	otic placode development	P	The process whose specific outcome is the progression of an otic placode over time, from its formation to the mature structure.
1905041	regulation of epithelium regeneration	P	Any process that modulates the frequency, rate or extent of epithelium regeneration.
1905042	negative regulation of epithelium regeneration	P	Any process that stops, prevents or reduces the frequency, rate or extent of epithelium regeneration.
1905043	positive regulation of epithelium regeneration	P	Any process that activates or increases the frequency, rate or extent of epithelium regeneration.
1905044	regulation of Schwann cell proliferation involved in axon regeneration	P	Any process that modulates the frequency, rate or extent of Schwann cell proliferation involved in axon regeneration.
1905045	negative regulation of Schwann cell proliferation involved in axon regeneration	P	Any process that stops, prevents or reduces the frequency, rate or extent of Schwann cell proliferation involved in axon regeneration.
1905046	positive regulation of Schwann cell proliferation involved in axon regeneration	P	Any process that activates or increases the frequency, rate or extent of Schwann cell proliferation involved in axon regeneration.
1905047	mitotic spindle pole body organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a mitotic spindle pole body.
1905048	regulation of metallopeptidase activity	P	Any process that modulates the frequency, rate or extent of metallopeptidase activity.
1905049	negative regulation of metallopeptidase activity	P	Any process that stops, prevents or reduces the frequency, rate or extent of metallopeptidase activity.
1905050	positive regulation of metallopeptidase activity	P	Any process that activates or increases the frequency, rate or extent of metallopeptidase activity.
1905051	regulation of base-excision repair	P	Any process that modulates the frequency, rate or extent of base-excision repair.
1905052	negative regulation of base-excision repair	P	Any process that stops, prevents or reduces the frequency, rate or extent of base-excision repair.
1905053	positive regulation of base-excision repair	P	Any process that activates or increases the frequency, rate or extent of base-excision repair.
1905054	calcium-induced calcium release activity involved in regulation of presynaptic cytosolic calcium ion concentration	F	Any calcium-induced calcium release activity that is involved in regulation of presynaptic cytosolic calcium ion concentration.
1905055	calcium:cation antiporter activity involved in regulation of presynaptic cytosolic calcium ion concentration	F	Any calcium:cation antiporter activity that is involved in regulation of presynaptic cytosolic calcium ion concentration.
1905056	calcium-transporting ATPase activity involved in regulation of presynaptic cytosolic calcium ion concentration	F	Any calcium-transporting ATPase activity that is involved in regulation of presynaptic cytosolic calcium ion concentration.
1905057	voltage-gated calcium channel activity involved in regulation of postsynaptic cytosolic calcium levels	F	Any voltage-gated calcium channel activity that is involved in regulation of postsynaptic cytosolic calcium ion concentration.
1905058	calcium-induced calcium release activity involved in regulation of postsynaptic cytosolic calcium ion concentration	F	Any calcium-induced calcium release activity that is involved in regulation of postsynaptic cytosolic calcium ion concentration.
1905059	calcium-transporting ATPase activity involved in regulation of postsynaptic cytosolic calcium ion concentration	F	Any calcium-transporting ATPase activity that is involved in regulation of postsynaptic cytosolic calcium ion concentration.
1905060	calcium:cation antiporter activity involved in regulation of postsynaptic cytosolic calcium ion concentration	F	Any calcium:cation antiporter activity that is involved in regulation of postsynaptic cytosolic calcium ion concentration.
1905061	negative regulation of cardioblast proliferation	P	Any process that stops, prevents or reduces the frequency, rate or extent of cardioblast proliferation.
1905062	positive regulation of cardioblast proliferation	P	Any process that activates or increases the frequency, rate or extent of cardioblast proliferation.
1905063	regulation of vascular smooth muscle cell differentiation	P	Any process that modulates the frequency, rate or extent of vascular smooth muscle cell differentiation.
1905064	negative regulation of vascular smooth muscle cell differentiation	P	Any process that stops, prevents or reduces the frequency, rate or extent of vascular smooth muscle cell differentiation.
1905065	positive regulation of vascular smooth muscle cell differentiation	P	Any process that activates or increases the frequency, rate or extent of vascular smooth muscle cell differentiation.
1905066	regulation of canonical Wnt signaling pathway involved in heart development	P	Any process that modulates the frequency, rate or extent of canonical Wnt signaling pathway involved in heart development.
1905067	negative regulation of canonical Wnt signaling pathway involved in heart development	P	Any process that stops, prevents or reduces the frequency, rate or extent of canonical Wnt signaling pathway involved in heart development.
1905068	positive regulation of canonical Wnt signaling pathway involved in heart development	P	Any process that activates or increases the frequency, rate or extent of canonical Wnt signaling pathway involved in heart development.
1905069	allantois development	P	The process whose specific outcome is the progression of an allantois over time, from its formation to the mature structure.
1905070	anterior visceral endoderm cell migration	P	The orderly movement of an anterior visceral endoderm cell from one site to another.
1905071	occluding junction disassembly	P	The disaggregation of an occluding junction into its constituent components.
1905072	cardiac jelly development	P	The process whose specific outcome is the progression of cardiac jelly over time, from its formation to the mature structure.
1905073	regulation of occluding junction disassembly	P	Any process that modulates the frequency, rate or extent of occluding junction disassembly.
1905074	negative regulation of occluding junction disassembly	P	Any process that stops, prevents or reduces the frequency, rate or extent of occluding junction disassembly.
1905075	positive regulation of occluding junction disassembly	P	Any process that activates or increases the frequency, rate or extent of occluding junction disassembly.
1905076	regulation of interleukin-17 secretion	P	Any process that modulates the frequency, rate or extent of interleukin-17 secretion.
1905077	negative regulation of interleukin-17 secretion	P	Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-17 secretion.
1905078	positive regulation of interleukin-17 secretion	P	Any process that activates or increases the frequency, rate or extent of interleukin-17 secretion.
1905079	regulation of cerebellar neuron development	P	Any process that modulates the frequency, rate or extent of cerebellar neuron development.
1905080	negative regulation of cerebellar neuron development	P	Any process that stops, prevents or reduces the frequency, rate or extent of cerebellar neuron development.
1905081	positive regulation of cerebellar neuron development	P	Any process that activates or increases the frequency, rate or extent of cerebellar neuron development.
1905082	regulation of mitochondrial translational elongation	P	Any process that modulates the frequency, rate or extent of mitochondrial translational elongation.
1905083	negative regulation of mitochondrial translational elongation	P	Any process that stops, prevents or reduces the frequency, rate or extent of mitochondrial translational elongation.
1905084	positive regulation of mitochondrial translational elongation	P	Any process that activates or increases the frequency, rate or extent of mitochondrial translational elongation.
1905085	regulation of bioluminescence	P	Any process that modulates the frequency, rate or extent of bioluminescence.
1905086	negative regulation of bioluminescence	P	Any process that stops, prevents or reduces the frequency, rate or extent of bioluminescence.
1905087	positive regulation of bioluminescence	P	Any process that activates or increases the frequency, rate or extent of bioluminescence.
1905088	positive regulation of synaptonemal complex assembly	P	Any process that activates or increases the frequency, rate or extent of synaptonemal complex assembly.
1905089	regulation of parkin-mediated mitophagy in response to mitochondrial depolarization	P	Any process that modulates the frequency, rate or extent of parkin-mediated mitophagy in response to mitochondrial depolarization.
1905090	negative regulation of parkin-mediated mitophagy in response to mitochondrial depolarization	P	Any process that stops, prevents or reduces the frequency, rate or extent of parkin-mediated mitophagy in response to mitochondrial depolarization.
1905091	positive regulation of parkin-mediated mitophagy in response to mitochondrial depolarization	P	Any process that activates or increases the frequency, rate or extent of parkin-mediated mitophagy in response to mitochondrial depolarization.
1905092	response to diosgenin	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diosgenin stimulus.
1905093	cellular response to diosgenin	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diosgenin stimulus.
1905094	regulation of apolipoprotein A-I-mediated signaling pathway	P	Any process that modulates the frequency, rate or extent of apolipoprotein A-I-mediated signaling pathway.
1905095	negative regulation of apolipoprotein A-I-mediated signaling pathway	P	Any process that stops, prevents or reduces the frequency, rate or extent of apolipoprotein A-I-mediated signaling pathway.
1905096	positive regulation of apolipoprotein A-I-mediated signaling pathway	P	Any process that activates or increases the frequency, rate or extent of apolipoprotein A-I-mediated signaling pathway.
1905097	regulation of guanyl-nucleotide exchange factor activity	P	Any process that modulates the frequency, rate or extent of guanyl-nucleotide exchange factor activity.
1905098	negative regulation of guanyl-nucleotide exchange factor activity	P	Any process that stops, prevents or reduces the frequency, rate or extent of guanyl-nucleotide exchange factor activity.
1905099	positive regulation of guanyl-nucleotide exchange factor activity	P	Any process that activates or increases the frequency, rate or extent of guanyl-nucleotide exchange factor activity.
1905100	regulation of apoptosome assembly	P	Any process that modulates the frequency, rate or extent of apoptosome assembly.
1905101	negative regulation of apoptosome assembly	P	Any process that stops, prevents or reduces the frequency, rate or extent of apoptosome assembly.
1905102	positive regulation of apoptosome assembly	P	Any process that activates or increases the frequency, rate or extent of apoptosome assembly.
1905103	integral component of lysosomal membrane	C	The component of the lysosome membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
1905108	guanosine binding	F	Interacting selectively and non-covalently with guanosine.
1905109	regulation of pulmonary blood vessel remodeling	P	Any process that modulates the frequency, rate or extent of pulmonary blood vessel remodeling.
1905110	negative regulation of pulmonary blood vessel remodeling	P	Any process that stops, prevents or reduces the frequency, rate or extent of pulmonary blood vessel remodeling.
1905111	positive regulation of pulmonary blood vessel remodeling	P	Any process that activates or increases the frequency, rate or extent of pulmonary blood vessel remodeling.
1905112	regulation of centromere clustering at the mitotic nuclear envelope	P	Any process that modulates the frequency, rate or extent of centromere clustering at the nuclear envelope.
1905113	positive regulation of centromere clustering at the mitotic nuclear envelope	P	Any process that activates or increases the frequency, rate or extent of centromere clustering at the nuclear envelope.
1905114	cell surface receptor signaling pathway involved in cell-cell signaling	P	Any cell surface receptor signaling pathway that is involved in cell-cell signaling.
1905115	regulation of lateral attachment of mitotic spindle microtubules to kinetochore	P	Any process that modulates the frequency, rate or extent of lateral attachment of mitotic spindle microtubules to kinetochore.
1905116	positive regulation of lateral attachment of mitotic spindle microtubules to kinetochore	P	Any process that activates or increases the frequency, rate or extent of lateral attachment of mitotic spindle microtubules to kinetochore.
1905117	regulation of ribonucleoside-diphosphate reductase activity	P	Any process that modulates the frequency, rate or extent of ribonucleoside-diphosphate reductase activity.
1905118	positive regulation of ribonucleoside-diphosphate reductase activity	P	Any process that activates or increases the frequency, rate or extent of ribonucleoside-diphosphate reductase activity.
1905119	response to haloperidol	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a haloperidol stimulus.
1905120	cellular response to haloperidol	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a haloperidol stimulus.
1905121	microtubule sliding involved in mitotic spindle elongation	P	Any microtubule sliding that is involved in mitotic spindle elongation.
1905122	polyamine import	P	The directed movement of polyamine macromolecule into a cell or organelle.
1905123	regulation of glucosylceramidase activity	P	Any process that modulates the frequency, rate or extent of glucosylceramidase activity.
1905124	negative regulation of glucosylceramidase activity	P	Any process that stops, prevents or reduces the frequency, rate or extent of glucosylceramidase activity.
1905125	positive regulation of glucosylceramidase activity	P	Any process that activates or increases the frequency, rate or extent of glucosylceramidase activity.
1905126	regulation of axo-dendritic protein transport	P	Any process that modulates the frequency, rate or extent of axo-dendritic protein transport.
1905127	negative regulation of axo-dendritic protein transport	P	Any process that stops, prevents or reduces the frequency, rate or extent of axo-dendritic protein transport.
1905128	positive regulation of axo-dendritic protein transport	P	Any process that activates or increases the frequency, rate or extent of axo-dendritic protein transport.
1905129	endocannabinoid signaling pathway involved in trans-synaptic signaling	P	Any endocannabinoid signaling pathway that is involved in trans-synaptic signaling by endocannabinoid.
1905130	carcinine import across plasma membrane	P	The directed movement of carcinine from outside of a cell into the cytoplasmic compartment.
1905131	carcinine transmembrane transporter activity	F	Catalysis of the transfer of carcinine from one side of the membrane to the other.
1905132	regulation of meiotic chromosome separation	P	Any process that modulates the frequency, rate or extent of meiotic chromosome separation.
1905133	negative regulation of meiotic chromosome separation	P	Any process that stops, prevents or reduces the frequency, rate or extent of meiotic chromosome separation.
1905134	positive regulation of meiotic chromosome separation	P	Any process that activates or increases the frequency, rate or extent of meiotic chromosome separation.
1905135	biotin import across plasma membrane	P	The directed movement of biotin from outside of a cell into the cytoplasmic compartment.
1905136	dethiobiotin import across plasma membrane	P	The directed movement of dethiobiotin from outside of a cell into the cytoplasmic compartment.
1905137	regulation of viral DNA genome packaging via site-specific sequence recognition	P	Any process that modulates the frequency, rate or extent of viral DNA genome packaging via site-specific sequence recognition.
1905138	positive regulation of viral DNA genome packaging via site-specific sequence recognition	P	Any process that activates or increases the frequency, rate or extent of viral DNA genome packaging via site-specific sequence recognition.
1905139	apical ectodermal ridge formation	P	The process that gives rise to the apical ectodermal ridge. This process pertains to the initial formation of a structure from unspecified parts.
1905140	regulation of apical ectodermal ridge formation	P	Any process that modulates the frequency, rate or extent of apical ectodermal ridge formation.
1905141	negative regulation of apical ectodermal ridge formation	P	Any process that stops, prevents or reduces the frequency, rate or extent of apical ectodermal ridge formation.
1905142	positive regulation of apical ectodermal ridge formation	P	Any process that activates or increases the frequency, rate or extent of apical ectodermal ridge formation.
1905143	eukaryotic translation initiation factor 2 complex assembly	P	The aggregation, arrangement and bonding together of a set of components to form an eukaryotic translation initiation factor 2 complex.
1905144	response to acetylcholine	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acetylcholine stimulus.
1905145	cellular response to acetylcholine	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acetylcholine stimulus.
1905146	lysosomal protein catabolic process	P	Any cellular protein catabolic process that takes place in a lysosome.
1905147	regulation of smooth muscle hypertrophy	P	Any process that modulates the frequency, rate or extent of smooth muscle hypertrophy.
1905148	negative regulation of smooth muscle hypertrophy	P	Any process that stops, prevents or reduces the frequency, rate or extent of smooth muscle hypertrophy.
1905149	positive regulation of smooth muscle hypertrophy	P	Any process that activates or increases the frequency, rate or extent of smooth muscle hypertrophy.
1905150	regulation of voltage-gated sodium channel activity	P	Any process that modulates the frequency, rate or extent of voltage-gated sodium channel activity.
1905151	negative regulation of voltage-gated sodium channel activity	P	Any process that stops, prevents or reduces the frequency, rate or extent of voltage-gated sodium channel activity.
1905152	positive regulation of voltage-gated sodium channel activity	P	Any process that activates or increases the frequency, rate or extent of voltage-gated sodium channel activity.
1905153	regulation of membrane invagination	P	Any process that modulates the frequency, rate or extent of membrane invagination.
1905154	negative regulation of membrane invagination	P	Any process that stops, prevents or reduces the frequency, rate or extent of membrane invagination.
1905155	positive regulation of membrane invagination	P	Any process that activates or increases the frequency, rate or extent of membrane invagination.
1905156	negative regulation of photosynthesis	P	Any process that stops, prevents or reduces the frequency, rate or extent of photosynthesis.
1905157	positive regulation of photosynthesis	P	Any process that activates or increases the frequency, rate or extent of photosynthesis.
1905161	protein localization to phagocytic vesicle	P	A process in which a protein is transported to, or maintained in, a location within a phagocytic vesicle.
1905162	regulation of phagosome maturation	P	Any process that modulates the frequency, rate or extent of phagosome maturation.
1905163	negative regulation of phagosome maturation	P	Any process that stops, prevents or reduces the frequency, rate or extent of phagosome maturation.
1905164	positive regulation of phagosome maturation	P	Any process that activates or increases the frequency, rate or extent of phagosome maturation.
1905165	regulation of lysosomal protein catabolic process	P	Any process that modulates the frequency, rate or extent of lysosomal protein catabolic process.
1905166	negative regulation of lysosomal protein catabolic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of lysosomal protein catabolic process.
1905167	positive regulation of lysosomal protein catabolic process	P	Any process that activates or increases the frequency, rate or extent of lysosomal protein catabolic process.
1905168	positive regulation of double-strand break repair via homologous recombination	P	Any process that activates or increases the frequency, rate or extent of double-strand break repair via homologous recombination.
1905169	regulation of protein localization to phagocytic vesicle	P	Any process that modulates the frequency, rate or extent of protein localization to phagocytic vesicle.
1905170	negative regulation of protein localization to phagocytic vesicle	P	Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to phagocytic vesicle.
1905171	positive regulation of protein localization to phagocytic vesicle	P	Any process that activates or increases the frequency, rate or extent of protein localization to phagocytic vesicle.
1905172	RISC complex binding	F	Interacting selectively and non-covalently with a RISC complex.
1905173	eukaryotic translation initiation factor 2B complex assembly	P	The aggregation, arrangement and bonding together of a set of components to form an eukaryotic translation initiation factor 2B complex.
1905174	regulation of vascular smooth muscle cell dedifferentiation	P	Any process that modulates the frequency, rate or extent of vascular smooth muscle cell dedifferentiation.
1905175	negative regulation of vascular smooth muscle cell dedifferentiation	P	Any process that stops, prevents or reduces the frequency, rate or extent of vascular smooth muscle cell dedifferentiation.
1905176	positive regulation of vascular smooth muscle cell dedifferentiation	P	Any process that activates or increases the frequency, rate or extent of vascular smooth muscle cell dedifferentiation.
1905177	tracheary element differentiation	P	The process in which a relatively unspecialized cell acquires the specialized features of a tracheary element.
1905178	regulation of cardiac muscle tissue regeneration	P	Any process that modulates the frequency, rate or extent of cardiac muscle tissue regeneration.
1905179	negative regulation of cardiac muscle tissue regeneration	P	Any process that stops, prevents or reduces the frequency, rate or extent of cardiac muscle tissue regeneration.
1905180	positive regulation of cardiac muscle tissue regeneration	P	Any process that activates or increases the frequency, rate or extent of cardiac muscle tissue regeneration.
1905181	regulation of urease activity	P	Any process that modulates the frequency, rate or extent of urease activity.
1905182	positive regulation of urease activity	P	Any process that activates or increases the frequency, rate or extent of urease activity.
1905183	negative regulation of protein serine/threonine phosphatase activity	P	Any process that stops, prevents or reduces the frequency, rate or extent of protein serine/threonine phosphatase activity.
1905184	positive regulation of protein serine/threonine phosphatase activity	P	Any process that activates or increases the frequency, rate or extent of protein serine/threonine phosphatase activity.
1905185	microtubule sliding involved in mitotic metaphase chromosome recapture	P	Any microtubule sliding that is involved in mitotic metaphase chromosome recapture.
1905186	regulation of metaphase/anaphase transition of meiosis I	P	Any process that modulates the frequency, rate or extent of metaphase/anaphase transition of meiosis I.
1905187	negative regulation of metaphase/anaphase transition of meiosis I	P	Any process that stops, prevents or reduces the frequency, rate or extent of metaphase/anaphase transition of meiosis I.
1905188	positive regulation of metaphase/anaphase transition of meiosis I	P	Any process that activates or increases the frequency, rate or extent of metaphase/anaphase transition of meiosis I.
1905189	regulation of metaphase/anaphase transition of meiosis II	P	Any process that modulates the frequency, rate or extent of metaphase/anaphase transition of meiosis II.
1905190	negative regulation of metaphase/anaphase transition of meiosis II	P	Any process that stops, prevents or reduces the frequency, rate or extent of metaphase/anaphase transition of meiosis II.
1905191	positive regulation of metaphase/anaphase transition of meiosis II	P	Any process that activates or increases the frequency, rate or extent of metaphase/anaphase transition of meiosis II.
1905192	regulation of chloroplast fission	P	Any process that modulates the frequency, rate or extent of chloroplast fission.
1905193	negative regulation of chloroplast fission	P	Any process that stops, prevents or reduces the frequency, rate or extent of chloroplast fission.
1905194	positive regulation of chloroplast fission	P	Any process that activates or increases the frequency, rate or extent of chloroplast fission.
1905195	regulation of ATPase activity, uncoupled	P	Any process that modulates the frequency, rate or extent of ATPase activity, uncoupled.
1905196	positive regulation of ATPase activity, uncoupled	P	Any process that activates or increases the frequency, rate or extent of ATPase activity, uncoupled.
1905197	endocannabinoid signaling pathway involved in retrograde trans-synaptic signaling	P	Any endocannabinoid signaling pathway that is involved in retrograde trans-synaptic signaling by endocannabinoid.
1905198	manchette assembly	P	The aggregation, arrangement and bonding together of a set of components to form a manchette.
1905199	manchette disassembly	P	The disaggregation of a manchette into its constituent components.
1905200	gibberellic acid transmembrane transport	P	The directed movement of gibberellic acid across a membrane.
1905201	gibberellin transmembrane transporter activity	F	Catalysis of the transfer of gibberellin from one side of the membrane to the other.
1905202	methylcrotonoyl-CoA carboxylase complex	C	A protein complex which is capable of methylcrotonoyl-CoA carboxylase activity.
1905203	regulation of connective tissue replacement	P	Any process that modulates the frequency, rate or extent of connective tissue replacement.
1905204	negative regulation of connective tissue replacement	P	Any process that stops, prevents or reduces the frequency, rate or extent of connective tissue replacement.
1905205	positive regulation of connective tissue replacement	P	Any process that activates or increases the frequency, rate or extent of connective tissue replacement.
1905206	positive regulation of hydrogen peroxide-induced cell death	P	Any process that activates or increases the frequency, rate or extent of cell death in response to hydrogen peroxide.
1905207	regulation of cardiocyte differentiation	P	Any process that modulates the frequency, rate or extent of cardiocyte differentiation.
1905208	negative regulation of cardiocyte differentiation	P	Any process that stops, prevents or reduces the frequency, rate or extent of cardiocyte differentiation.
1905209	positive regulation of cardiocyte differentiation	P	Any process that activates or increases the frequency, rate or extent of cardiocyte differentiation.
1905210	regulation of fibroblast chemotaxis	P	Any process that modulates the frequency, rate or extent of fibroblast chemotaxis.
1905211	negative regulation of fibroblast chemotaxis	P	Any process that stops, prevents or reduces the frequency, rate or extent of fibroblast chemotaxis.
1905212	positive regulation of fibroblast chemotaxis	P	Any process that activates or increases the frequency, rate or extent of fibroblast chemotaxis.
1905213	negative regulation of mitotic chromosome condensation	P	Any process that stops, prevents or reduces the frequency, rate or extent of mitotic chromosome condensation.
1905214	regulation of RNA binding	P	Any process that modulates the frequency, rate or extent of RNA binding.
1905215	negative regulation of RNA binding	P	Any process that stops, prevents or reduces the frequency, rate or extent of RNA binding.
1905216	positive regulation of RNA binding	P	Any process that activates or increases the frequency, rate or extent of RNA binding.
1905217	response to astaxanthin	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an astaxanthin stimulus.
1905218	cellular response to astaxanthin	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an astaxanthin stimulus.
1905219	regulation of platelet formation	P	Any process that modulates the frequency, rate or extent of platelet formation.
1905220	negative regulation of platelet formation	P	Any process that stops, prevents or reduces the frequency, rate or extent of platelet formation.
1905221	positive regulation of platelet formation	P	Any process that activates or increases the frequency, rate or extent of platelet formation.
1905222	atrioventricular canal morphogenesis	P	The developmental process by which an atrioventricular canal is generated and organized.
1905223	epicardium morphogenesis	P	The developmental process by which an epicardium is generated and organized.
1905224	clathrin-coated pit assembly	P	The aggregation, arrangement and bonding together of a set of components to form a clathrin-coated pit.
1905225	response to thyrotropin-releasing hormone	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a thyrotropin-releasing hormone (TRH) stimulus. TRH increases the secretion of thyroid-stimulating hormone by the anterior pituitary.
1905226	regulation of adhesion of symbiont to host epithelial cell	P	Any process that modulates the frequency, rate or extent of adhesion of symbiont to host epithelial cell.
1905227	negative regulation of adhesion of symbiont to host epithelial cell	P	Any process that stops, prevents or reduces the frequency, rate or extent of adhesion of symbiont to host epithelial cell.
1905228	positive regulation of adhesion of symbiont to host epithelial cell	P	Any process that activates or increases the frequency, rate or extent of adhesion of symbiont to host epithelial cell.
1905229	cellular response to thyrotropin-releasing hormone	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a thyrotropin-releasing hormone (TRH) stimulus. TRH increases the secretion of thyroid-stimulating hormone by the anterior pituitary.
1905230	response to borneol	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a borneol stimulus.
1905231	cellular response to borneol	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a borneol stimulus.
1905232	cellular response to L-glutamate	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-glutamate(1-) stimulus.
1905233	response to codeine	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a codeine stimulus.
1905234	cellular response to codeine	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a codeine stimulus.
1905235	response to quercetin	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a quercetin stimulus.
1905236	cellular response to quercetin	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a quercetin stimulus.
1905237	response to cyclosporin A	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cyclosporin A stimulus.
1905238	cellular response to cyclosporin A	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cyclosporin A stimulus.
1905239	regulation of canonical Wnt signaling pathway involved in osteoblast differentiation	P	Any process that modulates the frequency, rate or extent of canonical Wnt signaling pathway involved in osteoblast differentiation.
1905240	negative regulation of canonical Wnt signaling pathway involved in osteoblast differentiation	P	Any process that stops, prevents or reduces the frequency, rate or extent of canonical Wnt signaling pathway involved in osteoblast differentiation.
1905241	positive regulation of canonical Wnt signaling pathway involved in osteoblast differentiation	P	Any process that activates or increases the frequency, rate or extent of canonical Wnt signaling pathway involved in osteoblast differentiation.
1905242	response to 3,3',5-triiodo-L-thyronine	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 3,3',5-triiodo-L-thyronine stimulus.
1905243	cellular response to 3,3',5-triiodo-L-thyronine	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a 3,3',5-triiodo-L-thyronine stimulus.
1905244	regulation of modification of synaptic structure	P	Any process that modulates the frequency, rate or extent of modification of synaptic structure.
1905245	regulation of aspartic-type peptidase activity	P	Any process that modulates the frequency, rate or extent of aspartic-type peptidase activity.
1905246	negative regulation of aspartic-type peptidase activity	P	Any process that stops, prevents or reduces the frequency, rate or extent of aspartic-type peptidase activity.
1905247	positive regulation of aspartic-type peptidase activity	P	Any process that activates or increases the frequency, rate or extent of aspartic-type peptidase activity.
1905251	epidermal growth factor receptor signaling pathway involved in heart process	P	Any epidermal growth factor receptor signaling pathway that is involved in heart process.
1905255	regulation of RNA binding transcription factor activity	P	Any process that modulates the frequency, rate or extent of RNA binding transcription factor activity.
1905256	negative regulation of RNA binding transcription factor activity	P	Any process that stops, prevents or reduces the frequency, rate or extent of RNA binding transcription factor activity.
1905257	positive regulation of RNA binding transcription factor activity	P	Any process that activates or increases the frequency, rate or extent of RNA binding transcription factor activity.
1905258	regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway	P	Any process that modulates the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to nitrosative stress.
1905259	negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway	P	Any process that stops, prevents or reduces the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to nitrosative stress.
1905260	positive regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway	P	Any process that activates or increases the frequency, rate or extent of intrinsic apoptotic signaling pathway in response to nitrosative stress.
1905261	regulation of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination	P	Any process that modulates the frequency, rate or extent of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination.
1905262	negative regulation of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination	P	Any process that stops, prevents or reduces the frequency, rate or extent of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination.
1905263	positive regulation of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination	P	Any process that activates or increases the frequency, rate or extent of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination.
1905264	blasticidin S metabolic process	P	The chemical reactions and pathways involving blasticidin S.
1905265	blasticidin S catabolic process	P	The chemical reactions and pathways resulting in the breakdown of blasticidin S.
1905266	blasticidin S biosynthetic process	P	The chemical reactions and pathways resulting in the formation of blasticidin S.
1905267	endonucleolytic cleavage involved in tRNA processing	P	Any endonucleolytic RNA phosphodiester bond hydrolysis that is involved in tRNA processing.
1905268	negative regulation of chromatin organization	P	Any process that stops, prevents or reduces the frequency, rate or extent of chromatin organization.
1905269	positive regulation of chromatin organization	P	Any process that activates or increases the frequency, rate or extent of chromatin organization.
1905270	Meynert cell differentiation	P	The process in which a relatively unspecialized cell acquires the specialized features of a Meynert cell.
1905271	regulation of proton-transporting ATP synthase activity, rotational mechanism	P	Any process that modulates the frequency, rate or extent of proton-transporting ATP synthase activity, rotational mechanism.
1905272	negative regulation of proton-transporting ATP synthase activity, rotational mechanism	P	Any process that stops, prevents or reduces the frequency, rate or extent of proton-transporting ATP synthase activity, rotational mechanism.
1905273	positive regulation of proton-transporting ATP synthase activity, rotational mechanism	P	Any process that activates or increases the frequency, rate or extent of proton-transporting ATP synthase activity, rotational mechanism.
1905274	regulation of modification of postsynaptic actin cytoskeleton	P	Any process that modulates the frequency, rate or extent of modification of postsynaptic actin cytoskeleton.
1905275	Rohon-Beard neuron differentiation	P	The process in which a relatively unspecialized cell acquires the specialized features of a Rohon-Beard neuron.
1905276	regulation of epithelial tube formation	P	Any process that modulates the frequency, rate or extent of epithelial tube formation.
1905277	negative regulation of epithelial tube formation	P	Any process that stops, prevents or reduces the frequency, rate or extent of epithelial tube formation.
1905278	positive regulation of epithelial tube formation	P	Any process that activates or increases the frequency, rate or extent of epithelial tube formation.
1905279	regulation of retrograde transport, endosome to Golgi	P	Any process that modulates the frequency, rate or extent of retrograde transport, endosome to Golgi.
1905280	negative regulation of retrograde transport, endosome to Golgi	P	Any process that stops, prevents or reduces the frequency, rate or extent of retrograde transport, endosome to Golgi.
1905281	positive regulation of retrograde transport, endosome to Golgi	P	Any process that activates or increases the frequency, rate or extent of retrograde transport, endosome to Golgi.
1905282	regulation of epidermal growth factor receptor signaling pathway involved in heart process	P	Any process that modulates the frequency, rate or extent of epidermal growth factor receptor signaling pathway involved in heart process.
1905283	negative regulation of epidermal growth factor receptor signaling pathway involved in heart process	P	Any process that stops, prevents or reduces the frequency, rate or extent of epidermal growth factor receptor signaling pathway involved in heart process.
1905284	positive regulation of epidermal growth factor receptor signaling pathway involved in heart process	P	Any process that activates or increases the frequency, rate or extent of epidermal growth factor receptor signaling pathway involved in heart process.
1905285	fibrous ring of heart morphogenesis	P	The developmental process by which a fibrous ring of heart is generated and organized.
1905286	serine-type peptidase complex	C	A protein complex which is capable of serine-type peptidase activity.
1905287	positive regulation of G2/M transition of mitotic cell cycle involved in cellular response to nitrogen starvation	P	Any positive regulation of G2/M transition of mitotic cell cycle that is involved in cellular response to nitrogen starvation.
1905288	vascular associated smooth muscle cell apoptotic process	P	Any apoptotic process in a vascular associated smooth muscle cell.
1905289	regulation of CAMKK-AMPK signaling cascade	P	Any process that modulates the frequency, rate or extent of CAMKK-AMPK signaling cascade.
1905290	negative regulation of CAMKK-AMPK signaling cascade	P	Any process that stops, prevents or reduces the frequency, rate or extent of CAMKK-AMPK signaling cascade.
1905291	positive regulation of CAMKK-AMPK signaling cascade	P	Any process that activates or increases the frequency, rate or extent of CAMKK-AMPK signaling cascade.
1905292	regulation of neural crest cell differentiation	P	Any process that modulates the frequency, rate or extent of neural crest cell differentiation.
1905293	negative regulation of neural crest cell differentiation	P	Any process that stops, prevents or reduces the frequency, rate or extent of neural crest cell differentiation.
1905294	positive regulation of neural crest cell differentiation	P	Any process that activates or increases the frequency, rate or extent of neural crest cell differentiation.
1905295	regulation of neural crest cell fate specification	P	Any process that modulates the frequency, rate or extent of neural crest cell fate specification.
1905296	negative regulation of neural crest cell fate specification	P	Any process that stops, prevents or reduces the frequency, rate or extent of neural crest cell fate specification.
1905297	positive regulation of neural crest cell fate specification	P	Any process that activates or increases the frequency, rate or extent of neural crest cell fate specification.
1905298	regulation of intestinal epithelial cell development	P	Any process that modulates the frequency, rate or extent of intestinal epithelial cell development.
1905299	negative regulation of intestinal epithelial cell development	P	Any process that stops, prevents or reduces the frequency, rate or extent of intestinal epithelial cell development.
1905300	positive regulation of intestinal epithelial cell development	P	Any process that activates or increases the frequency, rate or extent of intestinal epithelial cell development.
1905301	regulation of macropinocytosis	P	Any process that modulates the frequency, rate or extent of macropinocytosis.
1905302	negative regulation of macropinocytosis	P	Any process that stops, prevents or reduces the frequency, rate or extent of macropinocytosis.
1905303	positive regulation of macropinocytosis	P	Any process that activates or increases the frequency, rate or extent of macropinocytosis.
1905304	regulation of cardiac myofibril assembly	P	Any process that modulates the frequency, rate or extent of cardiac myofibril assembly.
1905305	negative regulation of cardiac myofibril assembly	P	Any process that stops, prevents or reduces the frequency, rate or extent of cardiac myofibril assembly.
1905306	positive regulation of cardiac myofibril assembly	P	Any process that activates or increases the frequency, rate or extent of cardiac myofibril assembly.
1905307	response to miconazole	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a miconazole stimulus.
1905308	cellular response to miconazole	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a miconazole stimulus.
1905309	positive regulation of cohesin loading	P	Any process that activates or increases the frequency, rate or extent of cohesin loading.
1905310	regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis	P	Any process that modulates the frequency, rate or extent of cardiac neural crest cell migration involved in outflow tract morphogenesis.
1905311	negative regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis	P	Any process that stops, prevents or reduces the frequency, rate or extent of cardiac neural crest cell migration involved in outflow tract morphogenesis.
1905312	positive regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis	P	Any process that activates or increases the frequency, rate or extent of cardiac neural crest cell migration involved in outflow tract morphogenesis.
1905313	transforming growth factor beta receptor signaling pathway involved in heart development	P	Any transforming growth factor beta receptor signaling pathway that is involved in heart development.
1905314	semi-lunar valve development	P	The process whose specific outcome is the progression of a semi-lunar valve over time, from its formation to the mature structure.
1905315	cell proliferation involved in endocardial cushion morphogenesis	P	Any cell proliferation that is involved in endocardial cushion morphogenesis.
1905316	superior endocardial cushion morphogenesis	P	The developmental process by which a superior endocardial cushion is generated and organized.
1905317	inferior endocardial cushion morphogenesis	P	The developmental process by which an inferior endocardial cushion is generated and organized.
1905318	meiosis I spindle assembly checkpoint	P	Any spindle assembly checkpoint that is involved in meiosis I.
1905319	mesenchymal stem cell migration	P	The orderly movement of a mesenchymal stem cell from one site to another.
1905320	regulation of mesenchymal stem cell migration	P	Any process that modulates the frequency, rate or extent of mesenchymal stem cell migration.
1905321	negative regulation of mesenchymal stem cell migration	P	Any process that stops, prevents or reduces the frequency, rate or extent of mesenchymal stem cell migration.
1905322	positive regulation of mesenchymal stem cell migration	P	Any process that activates or increases the frequency, rate or extent of mesenchymal stem cell migration.
1905323	telomerase holoenzyme complex assembly	P	The aggregation, arrangement and bonding together of a set of components to form a telomerase holoenzyme complex.
1905324	telomere-telomerase complex assembly	P	The aggregation, arrangement and bonding together of a set of components to form a telomere-telomerase complex.
1905325	regulation of meiosis I spindle assembly checkpoint	P	Any process that modulates the frequency, rate or extent of the meiosis I spindle assembly checkpoint.
1905326	positive regulation of meiosis I spindle assembly checkpoint	P	Any process that activates or increases the frequency, rate or extent of the meiosis I spindle assembly checkpoint.
1905327	tracheoesophageal septum formation	P	The process that gives rise to the tracheoesophageal septum. This process pertains to the initial formation of a structure from unspecified parts.
1905328	plant septum development	P	The process whose specific outcome is the progression of a septum over time, from its formation to the mature structure.
1905329	sphingoid long-chain base transport	P	The directed movement of a sphingoid long-chain base, sometimes referred to as long-chain base, or sphingoid base, into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. Sphingoid long-chain bases are long-chain aliphatic amines that are the fundamental building blocks of sphingolipids. The main mammalian sphingoid long-chain bases are dihydrosphingosine and sphingosine, while dihydrosphingosine and phytosphingosine are the main sphingoid long-chain bases in yeast.
1905330	regulation of morphogenesis of an epithelium	P	Any process that modulates the frequency, rate or extent of morphogenesis of an epithelium.
1905331	negative regulation of morphogenesis of an epithelium	P	Any process that stops, prevents or reduces the frequency, rate or extent of morphogenesis of an epithelium.
1905332	positive regulation of morphogenesis of an epithelium	P	Any process that activates or increases the frequency, rate or extent of morphogenesis of an epithelium.
1905333	regulation of gastric motility	P	Any process that modulates the frequency, rate or extent of gastric motility.
1905334	Swi5-Sfr1 complex binding	F	Interacting selectively and non-covalently with a Swi5-Sfr1 complex.
1905335	regulation of aggrephagy	P	Any process that modulates the frequency, rate or extent of aggrephagy.
1905336	negative regulation of aggrephagy	P	Any process that stops, prevents or reduces the frequency, rate or extent of aggrephagy.
1905337	positive regulation of aggrephagy	P	Any process that activates or increases the frequency, rate or extent of aggrephagy.
1905338	negative regulation of cohesin unloading	P	Any process that stops, prevents or reduces the frequency, rate or extent of cohesin unloading.
1905339	positive regulation of cohesin unloading	P	Any process that activates or increases the frequency, rate or extent of cohesin unloading.
1905340	regulation of protein localization to kinetochore	P	Any process that modulates the frequency, rate or extent of protein localization to kinetochore.
1905341	negative regulation of protein localization to kinetochore	P	Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to kinetochore.
1905342	positive regulation of protein localization to kinetochore	P	Any process that activates or increases the frequency, rate or extent of protein localization to kinetochore.
1905343	regulation of cohesin unloading	P	Any process that modulates the frequency, rate or extent of cohesin unloading.
1905344	prostaglandin catabolic process	P	The chemical reactions and pathways resulting in the breakdown of prostaglandin.
1905345	protein localization to cleavage furrow	P	A process in which a protein is transported to, or maintained in, a location within a cleavage furrow.
1905346	protein localization to cleavage furrow rim	P	A process in which a protein is transported to, or maintained in, a location within a cleavage furrow rim.
1905347	endodeoxyribonuclease complex	C	A protein complex which is capable of endodeoxyribonuclease activity.
1905348	endonuclease complex	C	A protein complex which is capable of endonuclease activity.
1905349	ciliary transition zone assembly	P	The aggregation, arrangement and bonding together of a set of components to form a ciliary transition zone.
1905350	Y-shaped link assembly	P	The aggregation, arrangement and bonding together of a set of components to form a Y-shaped link. Two distinct protein complexes are known to be involved in proper linker assembly: the MKS complex and the NPHP complex. Improper assembly of Y-shaped links may cause malfunctioning of the transition zone as a molecular gate.
1905351	pericyte cell migration	P	The orderly movement of a pericyte cell from one site to another.
1905352	ciliary necklace assembly	P	The aggregation, arrangement and bonding together of a set of components to form a ciliary necklace.
1905353	ciliary transition fiber assembly	P	The aggregation, arrangement and bonding together of a set of components to form a ciliary transition fiber.
1905354	exoribonuclease complex	C	A protein complex which is capable of exoribonuclease activity.
1905355	spine apparatus assembly	P	The aggregation, arrangement and bonding together of a set of components to form a spine apparatus.
1905356	regulation of snRNA pseudouridine synthesis	P	Any process that modulates the frequency, rate or extent of snRNA pseudouridine synthesis.
1905357	negative regulation of snRNA pseudouridine synthesis	P	Any process that stops, prevents or reduces the frequency, rate or extent of snRNA pseudouridine synthesis.
1905358	positive regulation of snRNA pseudouridine synthesis	P	Any process that activates or increases the frequency, rate or extent of snRNA pseudouridine synthesis.
1905359	protein localization to meiotic spindle	P	A process in which a protein is transported to, or maintained in, a location within a meiotic spindle.
1905360	GTPase complex	C	A protein complex which is capable of GTPase activity.
1905361	L-serine transporter activity	F	Enables the directed movement of L-serine into, out of or within a cell, or between cells.
1905362	negative regulation of endosomal vesicle fusion	P	Any process that stops, prevents or reduces the frequency, rate or extent of endosomal vesicle fusion.
1905363	positive regulation of endosomal vesicle fusion	P	Any process that activates or increases the frequency, rate or extent of endosomal vesicle fusion.
1905364	regulation of endosomal vesicle fusion	P	Any process that modulates the frequency, rate or extent of endosomal vesicle fusion.
1905365	regulation of intralumenal vesicle formation	P	Any process that modulates the frequency, rate or extent of intralumenal vesicle formation.
1905366	negative regulation of intralumenal vesicle formation	P	Any process that stops, prevents or reduces the frequency, rate or extent of intralumenal vesicle formation.
1905367	positive regulation of intralumenal vesicle formation	P	Any process that activates or increases the frequency, rate or extent of intralumenal vesicle formation.
1905368	peptidase complex	C	A protein complex which is capable of peptidase activity.
1905369	endopeptidase complex	C	A protein complex which is capable of endopeptidase activity.
1905370	serine-type endopeptidase complex	C	A protein complex which is capable of serine-type endopeptidase activity.
1905371	ceramide phosphoethanolamine metabolic process	P	The chemical reactions and pathways involving ceramide phosphoethanolamine.
1905372	ceramide phosphoethanolamine catabolic process	P	The chemical reactions and pathways resulting in the breakdown of ceramide phosphoethanolamine.
1905373	ceramide phosphoethanolamine biosynthetic process	P	The chemical reactions and pathways resulting in the formation of ceramide phosphoethanolamine.
1905374	response to homocysteine	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a homocysteine stimulus.
1905375	cellular response to homocysteine	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a homocysteine stimulus.
1905376	negative regulation of cytochrome-c oxidase activity	P	Any process that stops, prevents or reduces the frequency, rate or extent of cytochrome-c oxidase activity.
1905377	response to D-galactose	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a D-galactose stimulus.
1905378	cellular response to D-galactose	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a D-galactose stimulus.
1905379	beta-N-acetylhexosaminidase complex	C	A protein complex which is capable of beta-N-acetylhexosaminidase activity.
1905380	regulation of snRNA transcription from RNA polymerase II promoter	P	Any process that modulates the frequency, rate or extent of snRNA transcription from RNA polymerase II promoter.
1905381	negative regulation of snRNA transcription from RNA polymerase II promoter	P	Any process that stops, prevents or reduces the frequency, rate or extent of snRNA transcription from RNA polymerase II promoter.
1905382	positive regulation of snRNA transcription from RNA polymerase II promoter	P	Any process that activates or increases the frequency, rate or extent of snRNA transcription from RNA polymerase II promoter.
1905383	protein localization to presynapse	P	A process in which a protein is transported to, or maintained in, a location within a presynapse.
1905384	regulation of protein localization to presynapse	P	Any process that modulates the frequency, rate or extent of protein localization to presynapse.
1905385	negative regulation of protein localization to presynapse	P	Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to presynapse.
1905386	positive regulation of protein localization to presynapse	P	Any process that activates or increases the frequency, rate or extent of protein localization to presynapse.
1905387	response to beta-carotene	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a beta-carotene stimulus.
1905388	cellular response to beta-carotene	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a beta-carotene stimulus.
1905389	response to leukotriene B4	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a leukotriene B4 stimulus.
1905390	cellular response to leukotriene B4	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a leukotriene B4 stimulus.
1905391	regulation of protein localization to cell division site involved in cell separation after cytokinesis	P	Any regulation of protein localization to cell division site that is involved in cell separation after cytokinesis.
1905392	plant organ morphogenesis	P	The developmental process by which a plant organ is generated and organized.
1905393	plant organ formation	P	The process that gives rise to the plant organ. This process pertains to the initial formation of a structure from unspecified parts.
1905394	retromer complex binding	F	Interacting selectively and non-covalently with a retromer complex.
1905395	response to flavonoid	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a flavonoid stimulus.
1905396	cellular response to flavonoid	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a flavonoid stimulus.
1905397	activated CD8-positive, alpha-beta T cell apoptotic process	P	Any apoptotic process in an activated CD8-positive, alpha-beta T cell.
1905398	activated CD4-positive, alpha-beta T cell apoptotic process	P	Any apoptotic process in an activated CD4-positive, alpha-beta T cell.
1905399	regulation of activated CD4-positive, alpha-beta T cell apoptotic process	P	Any process that modulates the frequency, rate or extent of activated CD4-positive, alpha-beta T cell apoptotic process.
1905400	negative regulation of activated CD4-positive, alpha-beta T cell apoptotic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of activated CD4-positive, alpha-beta T cell apoptotic process.
1905401	positive regulation of activated CD4-positive, alpha-beta T cell apoptotic process	P	Any process that activates or increases the frequency, rate or extent of activated CD4-positive, alpha-beta T cell apoptotic process.
1905402	regulation of activated CD8-positive, alpha-beta T cell apoptotic process	P	Any process that modulates the frequency, rate or extent of activated CD8-positive, alpha-beta T cell apoptotic process.
1905403	negative regulation of activated CD8-positive, alpha-beta T cell apoptotic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of activated CD8-positive, alpha-beta T cell apoptotic process.
1905404	positive regulation of activated CD8-positive, alpha-beta T cell apoptotic process	P	Any process that activates or increases the frequency, rate or extent of activated CD8-positive, alpha-beta T cell apoptotic process.
1905405	regulation of mitotic cohesin loading	P	Any process that modulates the frequency, rate or extent of mitotic cohesin loading.
1905406	positive regulation of mitotic cohesin loading	P	Any process that activates or increases the frequency, rate or extent of mitotic cohesin loading.
1905407	regulation of creatine transmembrane transporter activity	P	Any process that modulates the frequency, rate or extent of creatine transmembrane transporter activity.
1905408	negative regulation of creatine transmembrane transporter activity	P	Any process that stops, prevents or reduces the frequency, rate or extent of creatine transmembrane transporter activity.
1905409	positive regulation of creatine transmembrane transporter activity	P	Any process that activates or increases the frequency, rate or extent of creatine transmembrane transporter activity.
1905410	regulation of mitotic cohesin unloading	P	Any process that modulates the frequency, rate or extent of mitotic cohesin unloading.
1905411	positive regulation of mitotic cohesin unloading	P	Any process that activates or increases the frequency, rate or extent of mitotic cohesin unloading.
1905412	negative regulation of mitotic cohesin loading	P	Any process that stops, prevents or reduces the frequency, rate or extent of mitotic cohesin loading.
1905413	regulation of dense core granule exocytosis	P	Any process that modulates the frequency, rate or extent of dense core granule exocytosis.
1905414	negative regulation of dense core granule exocytosis	P	Any process that stops, prevents or reduces the frequency, rate or extent of dense core granule exocytosis.
1905415	positive regulation of dense core granule exocytosis	P	Any process that activates or increases the frequency, rate or extent of dense core granule exocytosis.
1905416	regulation of amoeboid sperm motility	P	Any process that modulates the frequency, rate or extent of amoeboid sperm motility.
1905417	negative regulation of amoeboid sperm motility	P	Any process that stops, prevents or reduces the frequency, rate or extent of amoeboid sperm motility.
1905418	positive regulation of amoeboid sperm motility	P	Any process that activates or increases the frequency, rate or extent of amoeboid sperm motility.
1905419	sperm flagellum movement involved in flagellated sperm motility	P	Any sperm flagellum movement that is involved in flagellated sperm motility.
1905420	vascular smooth muscle cell differentiation involved in phenotypic switching	P	Any vascular smooth muscle cell differentiation that is involved in phenotypic switching.
1905421	regulation of plant organ morphogenesis	P	Any process that modulates the frequency, rate or extent of plant organ morphogenesis.
1905422	negative regulation of plant organ morphogenesis	P	Any process that stops, prevents or reduces the frequency, rate or extent of plant organ morphogenesis.
1905423	positive regulation of plant organ morphogenesis	P	Any process that activates or increases the frequency, rate or extent of plant organ morphogenesis.
1905424	regulation of Wnt-mediated midbrain dopaminergic neuron differentiation	P	Any process that modulates the frequency, rate or extent of Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation.
1905425	negative regulation of Wnt-mediated midbrain dopaminergic neuron differentiation	P	Any process that stops, prevents or reduces the frequency, rate or extent of Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation.
1905426	positive regulation of Wnt-mediated midbrain dopaminergic neuron differentiation	P	Any process that activates or increases the frequency, rate or extent of Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation.
1905427	intracellular signal transduction involved in positive regulation of cell growth	P	Any intracellular signal transduction that is involved in positive regulation of cell growth.
1905428	regulation of plant organ formation	P	Any process that modulates the frequency, rate or extent of plant organ formation.
1905429	response to glycine	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glycine stimulus.
1905430	cellular response to glycine	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glycine stimulus.
1905431	microcystin transport	P	The directed movement of a microcystin into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
1905432	regulation of retrograde trans-synaptic signaling by neuropeptide	P	Any process that modulates the frequency, rate or extent of retrograde trans-synaptic signaling by neuropeptide.
1905433	negative regulation of retrograde trans-synaptic signaling by neuropeptide	P	Any process that stops, prevents or reduces the frequency, rate or extent of retrograde trans-synaptic signaling by neuropeptide.
1905434	positive regulation of retrograde trans-synaptic signaling by neuropeptide	P	Any process that activates or increases the frequency, rate or extent of retrograde trans-synaptic signaling by neuropeptide.
1905435	regulation of histone H3-K4 trimethylation	P	Any process that modulates the frequency, rate or extent of histone H3-K4 trimethylation.
1905436	negative regulation of histone H3-K4 trimethylation	P	Any process that stops, prevents or reduces the frequency, rate or extent of histone H3-K4 trimethylation.
1905437	positive regulation of histone H3-K4 trimethylation	P	Any process that activates or increases the frequency, rate or extent of histone H3-K4 trimethylation.
1905438	non-canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation	P	Any non-canonical Wnt signaling pathway that is involved in midbrain dopaminergic neuron differentiation.
1905439	response to chondroitin 6'-sulfate	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chondroitin 6'-sulfate stimulus.
1905440	cellular response to chondroitin 6'-sulfate	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chondroitin 6'-sulfate stimulus.
1905441	response to chondroitin 4'-sulfate	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chondroitin 4'-sulfate stimulus.
1905442	cellular response to chondroitin 4'-sulfate	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chondroitin 4'-sulfate stimulus.
1905443	regulation of clathrin coat assembly	P	Any process that modulates the frequency, rate or extent of clathrin coat assembly.
1905444	negative regulation of clathrin coat assembly	P	Any process that stops, prevents or reduces the frequency, rate or extent of clathrin coat assembly.
1905445	positive regulation of clathrin coat assembly	P	Any process that activates or increases the frequency, rate or extent of clathrin coat assembly.
1905446	regulation of mitochondrial ATP synthesis coupled electron transport	P	Any process that modulates the frequency, rate or extent of mitochondrial ATP synthesis coupled electron transport.
1905447	negative regulation of mitochondrial ATP synthesis coupled electron transport	P	Any process that stops, prevents or reduces the frequency, rate or extent of mitochondrial ATP synthesis coupled electron transport.
1905448	positive regulation of mitochondrial ATP synthesis coupled electron transport	P	Any process that activates or increases the frequency, rate or extent of mitochondrial ATP synthesis coupled electron transport.
1905449	regulation of Fc-gamma receptor signaling pathway involved in phagocytosis	P	Any process that modulates the frequency, rate or extent of Fc-gamma receptor signaling pathway involved in phagocytosis.
1905450	negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis	P	Any process that stops, prevents or reduces the frequency, rate or extent of Fc-gamma receptor signaling pathway involved in phagocytosis.
1905451	positive regulation of Fc-gamma receptor signaling pathway involved in phagocytosis	P	Any process that activates or increases the frequency, rate or extent of Fc-gamma receptor signaling pathway involved in phagocytosis.
1905453	regulation of myeloid progenitor cell differentiation	P	Any process that modulates the frequency, rate or extent of myeloid progenitor cell differentiation.
1905454	negative regulation of myeloid progenitor cell differentiation	P	Any process that stops, prevents or reduces the frequency, rate or extent of myeloid progenitor cell differentiation.
1905455	positive regulation of myeloid progenitor cell differentiation	P	Any process that activates or increases the frequency, rate or extent of myeloid progenitor cell differentiation.
1905456	regulation of lymphoid progenitor cell differentiation	P	Any process that modulates the frequency, rate or extent of lymphoid progenitor cell differentiation.
1905457	negative regulation of lymphoid progenitor cell differentiation	P	Any process that stops, prevents or reduces the frequency, rate or extent of lymphoid progenitor cell differentiation.
1905458	positive regulation of lymphoid progenitor cell differentiation	P	Any process that activates or increases the frequency, rate or extent of lymphoid progenitor cell differentiation.
1905459	regulation of vascular associated smooth muscle cell apoptotic process	P	Any process that modulates the frequency, rate or extent of vascular associated smooth muscle cell apoptotic process.
1905460	negative regulation of vascular associated smooth muscle cell apoptotic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of vascular associated smooth muscle cell apoptotic process.
1905461	positive regulation of vascular associated smooth muscle cell apoptotic process	P	Any process that activates or increases the frequency, rate or extent of vascular associated smooth muscle cell apoptotic process.
1905462	regulation of DNA duplex unwinding	P	Any process that modulates the frequency, rate or extent of DNA duplex unwinding.
1905463	negative regulation of DNA duplex unwinding	P	Any process that stops, prevents or reduces the frequency, rate or extent of DNA duplex unwinding.
1905464	positive regulation of DNA duplex unwinding	P	Any process that activates or increases the frequency, rate or extent of DNA duplex unwinding.
1905465	regulation of G-quadruplex DNA unwinding	P	Any process that modulates the frequency, rate or extent of G-quadruplex DNA unwinding.
1905466	negative regulation of G-quadruplex DNA unwinding	P	Any process that stops, prevents or reduces the frequency, rate or extent of G-quadruplex DNA unwinding.
1905467	positive regulation of G-quadruplex DNA unwinding	P	Any process that activates or increases the frequency, rate or extent of G-quadruplex DNA unwinding.
1905468	regulation of clathrin-coated pit assembly	P	Any process that modulates the frequency, rate or extent of clathrin-coated pit assembly.
1905469	negative regulation of clathrin-coated pit assembly	P	Any process that stops, prevents or reduces the frequency, rate or extent of clathrin-coated pit assembly.
1905470	positive regulation of clathrin-coated pit assembly	P	Any process that activates or increases the frequency, rate or extent of clathrin-coated pit assembly.
1905471	regulation of histone H3-K79 dimethylation	P	Any process that modulates the frequency, rate or extent of histone H3-K79 dimethylation.
1905472	negative regulation of histone H3-K79 dimethylation	P	Any process that stops, prevents or reduces the frequency, rate or extent of histone H3-K79 dimethylation.
1905473	positive regulation of histone H3-K79 dimethylation	P	Any process that activates or increases the frequency, rate or extent of histone H3-K79 dimethylation.
1905474	canonical Wnt signaling pathway involved in stem cell proliferation	P	Any canonical Wnt signaling pathway that is involved in stem cell proliferation.
1905475	regulation of protein localization to membrane	P	Any process that modulates the frequency, rate or extent of protein localization to membrane.
1905476	negative regulation of protein localization to membrane	P	Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to membrane.
1905477	positive regulation of protein localization to membrane	P	Any process that activates or increases the frequency, rate or extent of protein localization to membrane.
1905478	regulation of glutamate-ammonia ligase activity	P	Any process that modulates the frequency, rate or extent of glutamate-ammonia ligase activity.
1905479	negative regulation of glutamate-ammonia ligase activity	P	Any process that stops, prevents or reduces the frequency, rate or extent of glutamate-ammonia ligase activity.
1905480	positive regulation of glutamate-ammonia ligase activity	P	Any process that activates or increases the frequency, rate or extent of glutamate-ammonia ligase activity.
1905481	cytoplasmic sequestering of protein involved in mitotic DNA replication checkpoint	P	Any cytoplasmic sequestering of protein that is involved in mitotic DNA replication checkpoint.
1905482	cytoplasmic sequestering of protein involved in G2 DNA damage checkpoint	P	Any cytoplasmic sequestering of protein that is involved in G2 DNA damage checkpoint.
1905483	regulation of motor neuron migration	P	Any process that modulates the frequency, rate or extent of motor neuron migration.
1905484	negative regulation of motor neuron migration	P	Any process that stops, prevents or reduces the frequency, rate or extent of motor neuron migration.
1905485	positive regulation of motor neuron migration	P	Any process that activates or increases the frequency, rate or extent of motor neuron migration.
1905486	regulation of anterior/posterior axon guidance	P	Any process that modulates the frequency, rate or extent of anterior/posterior axon guidance.
1905487	negative regulation of anterior/posterior axon guidance	P	Any process that stops, prevents or reduces the frequency, rate or extent of anterior/posterior axon guidance.
1905488	positive regulation of anterior/posterior axon guidance	P	Any process that activates or increases the frequency, rate or extent of anterior/posterior axon guidance.
1905489	regulation of sensory neuron axon guidance	P	Any process that modulates the frequency, rate or extent of sensory neuron axon guidance.
1905490	negative regulation of sensory neuron axon guidance	P	Any process that stops, prevents or reduces the frequency, rate or extent of sensory neuron axon guidance.
1905491	positive regulation of sensory neuron axon guidance	P	Any process that activates or increases the frequency, rate or extent of sensory neuron axon guidance.
1905492	positive regulation of branching morphogenesis of a nerve	P	Any process that activates or increases the frequency, rate or extent of branching morphogenesis of a nerve.
1905493	regulation of G-quadruplex DNA binding	P	Any process that modulates the frequency, rate or extent of G-quadruplex DNA binding.
1905494	negative regulation of G-quadruplex DNA binding	P	Any process that stops, prevents or reduces the frequency, rate or extent of G-quadruplex DNA binding.
1905495	positive regulation of G-quadruplex DNA binding	P	Any process that activates or increases the frequency, rate or extent of G-quadruplex DNA binding.
1905496	regulation of triplex DNA binding	P	Any process that modulates the frequency, rate or extent of triplex DNA binding.
1905497	negative regulation of triplex DNA binding	P	Any process that stops, prevents or reduces the frequency, rate or extent of triplex DNA binding.
1905498	positive regulation of triplex DNA binding	P	Any process that activates or increases the frequency, rate or extent of triplex DNA binding.
1905499	trichome papilla formation	P	The aggregation, arrangement and bonding together of a set of components to form a trichome papilla.
1905502	acetyl-CoA binding	F	Interacting selectively and non-covalently with acetyl-CoA.
1905503	regulation of motile cilium assembly	P	Any process that modulates the frequency, rate or extent of motile cilium assembly.
1905504	negative regulation of motile cilium assembly	P	Any process that stops, prevents or reduces the frequency, rate or extent of motile cilium assembly.
1905505	positive regulation of motile cilium assembly	P	Any process that activates or increases the frequency, rate or extent of motile cilium assembly.
1905506	gerontoplast stroma	C	Any plastid stroma that is part of a gerontoplast.
1905507	cytoplasmic sequestering of protein involved in mitotic G2 DNA damage checkpoint	P	Any cytoplasmic sequestering of protein that is involved in mitotic G2 DNA damage checkpoint.
1905508	protein localization to microtubule organizing center	P	A process in which a protein is transported to, or maintained in, a location within a microtubule organizing center.
1905509	protein localization to interphase microtubule organizing center	P	A process in which a protein is transported to, or maintained in, a location within an interphase microtubule organizing center.
1905510	negative regulation of myosin II filament assembly	P	Any process that stops, prevents or reduces the frequency, rate or extent of myosin II filament assembly.
1905511	positive regulation of myosin II filament assembly	P	Any process that activates or increases the frequency, rate or extent of myosin II filament assembly.
1905512	regulation of short-term synaptic potentiation	P	Any process that modulates the frequency, rate or extent of short-term synaptic potentiation.
1905513	negative regulation of short-term synaptic potentiation	P	Any process that stops, prevents or reduces the frequency, rate or extent of short-term synaptic potentiation.
1905514	positive regulation of short-term synaptic potentiation	P	Any process that activates or increases the frequency, rate or extent of short-term synaptic potentiation.
1905515	non-motile cilium assembly	P	The aggregation, arrangement and bonding together of a set of components to form a non-motile cilium.
1905516	positive regulation of fertilization	P	Any process that activates or increases the frequency, rate or extent of fertilization.
1905517	macrophage migration	P	The orderly movement of a macrophage from one site to another.
1905518	regulation of presynaptic active zone assembly	P	Any process that modulates the frequency, rate or extent of presynaptic active zone assembly.
1905519	negative regulation of presynaptic active zone assembly	P	Any process that stops, prevents or reduces the frequency, rate or extent of presynaptic active zone assembly.
1905520	positive regulation of presynaptic active zone assembly	P	Any process that activates or increases the frequency, rate or extent of presynaptic active zone assembly.
1905521	regulation of macrophage migration	P	Any process that modulates the frequency, rate or extent of macrophage migration.
1905522	negative regulation of macrophage migration	P	Any process that stops, prevents or reduces the frequency, rate or extent of macrophage migration.
1905523	positive regulation of macrophage migration	P	Any process that activates or increases the frequency, rate or extent of macrophage migration.
1905524	negative regulation of protein autoubiquitination	P	Any process that stops, prevents or reduces the frequency, rate or extent of protein autoubiquitination.
1905526	regulation of Golgi lumen acidification	P	Any process that modulates the frequency, rate or extent of Golgi lumen acidification.
1905527	negative regulation of Golgi lumen acidification	P	Any process that stops, prevents or reduces the frequency, rate or extent of Golgi lumen acidification.
1905528	positive regulation of Golgi lumen acidification	P	Any process that activates or increases the frequency, rate or extent of Golgi lumen acidification.
1905529	regulation of uracil import across plasma membrane	P	Any process that modulates the frequency, rate or extent of uracil import across plasma membrane.
1905530	negative regulation of uracil import across plasma membrane	P	Any process that stops, prevents or reduces the frequency, rate or extent of uracil import across plasma membrane.
1905531	positive regulation of uracil import across plasma membrane	P	Any process that activates or increases the frequency, rate or extent of uracil import across plasma membrane.
1905532	regulation of leucine import across plasma membrane	P	Any process that modulates the frequency, rate or extent of leucine import across plasma membrane.
1905533	negative regulation of leucine import across plasma membrane	P	Any process that stops, prevents or reduces the frequency, rate or extent of leucine import across plasma membrane.
1905534	positive regulation of leucine import across plasma membrane	P	Any process that activates or increases the frequency, rate or extent of leucine import across plasma membrane.
1905535	regulation of eukaryotic translation initiation factor 4F complex assembly	P	Any process that modulates the frequency, rate or extent of eukaryotic translation initiation factor 4F complex assembly.
1905536	negative regulation of eukaryotic translation initiation factor 4F complex assembly	P	Any process that stops, prevents or reduces the frequency, rate or extent of eukaryotic translation initiation factor 4F complex assembly.
1905537	positive regulation of eukaryotic translation initiation factor 4F complex assembly	P	Any process that activates or increases the frequency, rate or extent of eukaryotic translation initiation factor 4F complex assembly.
1905538	polysome binding	F	Interacting selectively and non-covalently with a polysome.
1905539	regulation of postsynapse to nucleus signaling pathway	P	Any process that modulates the frequency, rate or extent of postsynapse to nucleus signaling pathway.
1905540	interleukin-7 receptor complex	C	A protein complex that binds interleukin-7 (IL-7) and that consists of, at a minimum, an interleukin, an alpha and a gamma chain as well as optional additional kinase subunits. The alpha chain binds IL-7 with high affinity and subsequently binds the cytokine receptor common gamma chain that forms part of multiple interleukin receptors.
1905541	regulation of L-arginine import across plasma membrane	P	Any process that modulates the frequency, rate or extent of L-arginine import across plasma membrane.
1905542	negative regulation of L-arginine import across plasma membrane	P	Any process that stops, prevents or reduces the frequency, rate or extent of L-arginine import across plasma membrane.
1905543	interleukin-15 receptor complex	C	A protein complex that binds interleukin-15 (IL-15) and that consists of, at a minimum, an interleukin, an alpha, beta and gamma chain as well as optional additional kinase subunits. The alpha chain is unique to binds IL-15 while it shares the beta chain with the IL-2 receptor and the cytokine receptor common gamma chain with multiple interleukin receptors.
1905544	L-methionine import across plasma membrane	P	The directed movement of L-methionine from outside of a cell into the cytoplasmic compartment.
1905546	cellular response to phenylpropanoid	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a phenylpropanoid stimulus.
1905547	regulation of telomeric heterochromatin assembly	P	Any process that modulates the frequency, rate or extent of telomeric heterochromatin assembly.
1905548	negative regulation of telomeric heterochromatin assembly	P	Any process that stops, prevents or reduces the frequency, rate or extent of telomeric heterochromatin assembly.
1905549	positive regulation of telomeric heterochromatin assembly	P	Any process that activates or increases the frequency, rate or extent of telomeric heterochromatin assembly.
1905550	regulation of protein localization to endoplasmic reticulum	P	Any process that modulates the frequency, rate or extent of protein localization to endoplasmic reticulum.
1905551	negative regulation of protein localization to endoplasmic reticulum	P	Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to endoplasmic reticulum.
1905552	positive regulation of protein localization to endoplasmic reticulum	P	Any process that activates or increases the frequency, rate or extent of protein localization to endoplasmic reticulum.
1905553	regulation of blood vessel branching	P	Any process that modulates the frequency, rate or extent of blood vessel branching.
1905554	negative regulation of vessel branching	P	Any process that stops, prevents or reduces the frequency, rate or extent of blood vessel branching.
1905555	positive regulation blood vessel branching	P	Any process that activates or increases the frequency, rate or extent of blood vessel branching.
1905556	ciliary vesicle assembly	P	The aggregation, arrangement and bonding together of a set of components to form a ciliary vesicle. Multiple smaller vesicles dock to the transitional fibers on a mature basal body and then fuse together to form a larger single vesicle. This then fuses with the plasma membrane and forms the ciliary membrane.
1905557	regulation of mitotic nuclear envelope disassembly	P	Any process that modulates the frequency, rate or extent of mitotic nuclear envelope disassembly.
1905558	negative regulation of mitotic nuclear envelope disassembly	P	Any process that stops, prevents or reduces the frequency, rate or extent of mitotic nuclear envelope disassembly.
1905559	positive regulation of mitotic nuclear envelope disassembly	P	Any process that activates or increases the frequency, rate or extent of mitotic nuclear envelope disassembly.
1905560	negative regulation of kinetochore assembly	P	Any process that stops, prevents or reduces the frequency, rate or extent of kinetochore assembly.
1905561	positive regulation of kinetochore assembly	P	Any process that activates or increases the frequency, rate or extent of kinetochore assembly.
1905562	regulation of vascular endothelial cell proliferation	P	Any process that modulates the frequency, rate or extent of vascular endothelial cell proliferation.
1905563	negative regulation of vascular endothelial cell proliferation	P	Any process that stops, prevents or reduces the frequency, rate or extent of vascular endothelial cell proliferation.
1905564	positive regulation of vascular endothelial cell proliferation	P	Any process that activates or increases the frequency, rate or extent of vascular endothelial cell proliferation.
1905568	regulation of ferrichrome biosynthetic process	P	Any process that modulates the frequency, rate or extent of ferrichrome biosynthetic process.
1905569	negative regulation of ferrichrome biosynthetic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of ferrichrome biosynthetic process.
1905570	positive regulation of ferrichrome biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of ferrichrome biosynthetic process.
1905571	interleukin-10 receptor complex	C	A protein complex that binds interleukin-10 (IL-10) and that consists of, at a minimum, a dimeric interleukin, an alpha and a beta chain as well as optional additional kinase subunits. The alpha chain binds IL-10 with high affinity and subsequently binds the common beta receptor chain that forms part of multiple interleukin receptors.
1905572	ganglioside GM1 transport to membrane	P	The directed movement of ganglioside GM1 to membrane.
1905573	ganglioside GM1 binding	F	Interacting selectively and non-covalently with ganglioside GM1.
1905574	ganglioside GM2 binding	F	Interacting selectively and non-covalently with ganglioside GM2.
1905575	ganglioside GM3 binding	F	Interacting selectively and non-covalently with ganglioside GM3.
1905576	ganglioside GT1b binding	F	Interacting selectively and non-covalently with ganglioside GT1b.
1905577	ganglioside GP1c binding	F	Interacting selectively and non-covalently with ganglioside GP1c.
1905578	regulation of ERBB3 signaling pathway	P	Any process that modulates the frequency, rate or extent of ERBB3 signaling pathway.
1905579	negative regulation of ERBB3 signaling pathway	P	Any process that stops, prevents or reduces the frequency, rate or extent of ERBB3 signaling pathway.
1905580	positive regulation of ERBB3 signaling pathway	P	Any process that activates or increases the frequency, rate or extent of ERBB3 signaling pathway.
1905581	positive regulation of low-density lipoprotein particle clearance	P	Any process that activates or increases the frequency, rate or extent of low-density lipoprotein particle clearance.
1905582	response to mannose	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mannose stimulus.
1905583	cellular response to mannose	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mannose stimulus.
1905584	outer hair cell apoptotic process	P	Any apoptotic process in an outer hair cell.
1905585	regulation of outer hair cell apoptotic process	P	Any process that modulates the frequency, rate or extent of outer hair cell apoptotic process.
1905586	negative regulation of outer hair cell apoptotic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of outer hair cell apoptotic process.
1905587	positive regulation of outer hair cell apoptotic process	P	Any process that activates or increases the frequency, rate or extent of outer hair cell apoptotic process.
1905588	plant-type cell wall modification involved in stomatal movement	P	Any plant-type cell wall modification that is involved in stomatal movement.
1905589	positive regulation of L-arginine import across plasma membrane	P	Any process that activates or increases the frequency, rate or extent of L-arginine import across plasma membrane.
1905590	fibronectin fibril organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a fibronectin fibril.
1905591	regulation of optical nerve axon regeneration	P	Any process that modulates the frequency, rate or extent of optical nerve axon regeneration.
1905592	negative regulation of optical nerve axon regeneration	P	Any process that stops, prevents or reduces the frequency, rate or extent of optical nerve axon regeneration.
1905593	positive regulation of optical nerve axon regeneration	P	Any process that activates or increases the frequency, rate or extent of optical nerve axon regeneration.
1905594	resveratrol binding	F	Interacting selectively and non-covalently with resveratrol.
1905595	regulation of low-density lipoprotein particle receptor binding	P	Any process that modulates the frequency, rate or extent of low-density lipoprotein particle receptor binding.
1905596	negative regulation of low-density lipoprotein particle receptor binding	P	Any process that stops, prevents or reduces the frequency, rate or extent of low-density lipoprotein particle receptor binding.
1905597	positive regulation of low-density lipoprotein particle receptor binding	P	Any process that activates or increases the frequency, rate or extent of low-density lipoprotein particle receptor binding.
1905598	negative regulation of low-density lipoprotein receptor activity	P	Any process that stops, prevents or reduces the frequency, rate or extent of low-density lipoprotein receptor activity.
1905599	positive regulation of low-density lipoprotein receptor activity	P	Any process that activates or increases the frequency, rate or extent of low-density lipoprotein receptor activity.
1905600	regulation of receptor-mediated endocytosis involved in cholesterol transport	P	Any process that modulates the frequency, rate or extent of receptor-mediated endocytosis involved in cholesterol transport.
1905601	negative regulation of receptor-mediated endocytosis involved in cholesterol transport	P	Any process that stops, prevents or reduces the frequency, rate or extent of receptor-mediated endocytosis involved in cholesterol transport.
1905602	positive regulation of receptor-mediated endocytosis involved in cholesterol transport	P	Any process that activates or increases the frequency, rate or extent of receptor-mediated endocytosis involved in cholesterol transport.
1905603	regulation of maintenance of permeability of blood-brain barrier	P	Any process that modulates the frequency, rate or extent of maintenance of permeability of blood-brain barrier.
1905604	negative regulation of maintenance of permeability of blood-brain barrier	P	Any process that stops, prevents or reduces the frequency, rate or extent of maintenance of permeability of blood-brain barrier.
1905605	positive regulation of maintenance of permeability of blood-brain barrier	P	Any process that activates or increases the frequency, rate or extent of maintenance of permeability of blood-brain barrier.
1905606	regulation of presynapse assembly	P	Any process that modulates the frequency, rate or extent of presynapse assembly.
1905607	negative regulation of presynapse assembly	P	Any process that stops, prevents or reduces the frequency, rate or extent of presynapse assembly.
1905608	positive regulation of presynapse assembly	P	Any process that activates or increases the frequency, rate or extent of presynapse assembly.
1905609	positive regulation of smooth muscle cell-matrix adhesion	P	Any process that activates or increases the frequency, rate or extent of smooth muscle cell-matrix adhesion.
1905610	regulation of mRNA cap binding	P	Any process that modulates the frequency, rate or extent of mRNA cap binding.
1905611	negative regulation of mRNA cap binding	P	Any process that stops, prevents or reduces the frequency, rate or extent of mRNA cap binding.
1905612	positive regulation of mRNA cap binding	P	Any process that activates or increases the frequency, rate or extent of mRNA cap binding.
1905613	regulation of developmental vegetative growth	P	Any process that modulates the frequency, rate or extent of developmental vegetative growth.
1905614	negative regulation of developmental vegetative growth	P	Any process that stops, prevents or reduces the frequency, rate or extent of developmental vegetative growth.
1905615	positive regulation of developmental vegetative growth	P	Any process that activates or increases the frequency, rate or extent of developmental vegetative growth.
1905616	regulation of miRNA mediated inhibition of translation	P	Any process that modulates the frequency, rate or extent of miRNA mediated inhibition of translation.
1905617	negative regulation of miRNA mediated inhibition of translation	P	Any process that stops, prevents or reduces the frequency, rate or extent of miRNA mediated inhibition of translation.
1905618	positive regulation of miRNA mediated inhibition of translation	P	Any process that activates or increases the frequency, rate or extent of miRNA mediated inhibition of translation.
1905619	regulation of alpha-(1->3)-fucosyltransferase activity	P	Any process that modulates the frequency, rate or extent of alpha-(1->3)-fucosyltransferase activity.
1905620	negative regulation of alpha-(1->3)-fucosyltransferase activity	P	Any process that stops, prevents or reduces the frequency, rate or extent of alpha-(1->3)-fucosyltransferase activity.
1905621	positive regulation of alpha-(1->3)-fucosyltransferase activity	P	Any process that activates or increases the frequency, rate or extent of alpha-(1->3)-fucosyltransferase activity.
1905622	negative regulation of leaf development	P	Any process that stops, prevents or reduces the frequency, rate or extent of leaf development.
1905623	positive regulation of leaf development	P	Any process that activates or increases the frequency, rate or extent of leaf development.
1905624	regulation of L-methionine import across plasma membrane	P	Any process that modulates the frequency, rate or extent of L-methionine import across plasma membrane.
1905625	negative regulation of L-methionine import across plasma membrane	P	Any process that stops, prevents or reduces the frequency, rate or extent of L-methionine import across plasma membrane.
1905626	positive regulation of L-methionine import across plasma membrane	P	Any process that activates or increases the frequency, rate or extent of L-methionine import across plasma membrane.
1905627	regulation of serotonin biosynthetic process	P	Any process that modulates the frequency, rate or extent of serotonin biosynthetic process.
1905628	negative regulation of serotonin biosynthetic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of serotonin biosynthetic process.
1905629	positive regulation of serotonin biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of serotonin biosynthetic process.
1905630	response to glyceraldehyde	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glyceraldehyde stimulus.
1905631	cellular response to glyceraldehyde	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glyceraldehyde stimulus.
1905632	protein localization to euchromatin	P	A process in which a protein is transported to, or maintained in, a location within an euchromatin.
1905633	establishment of protein localization to euchromatin	P	The directed movement of a protein to a specific location in an euchromatin.
1905634	regulation of protein localization to chromatin	P	Any process that modulates the frequency, rate or extent of protein localization to chromatin.
1905635	FACT complex assembly	P	The aggregation, arrangement and bonding together of a set of components to form a FACT complex.
1905636	positive regulation of RNA polymerase II regulatory region sequence-specific DNA binding	P	Any process that activates or increases the frequency, rate or extent of RNA polymerase II regulatory region sequence-specific DNA binding.
1905637	regulation of mitochondrial mRNA catabolic process	P	Any process that modulates the frequency, rate or extent of mitochondrial mRNA catabolic process.
1905638	negative regulation of mitochondrial mRNA catabolic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of mitochondrial mRNA catabolic process.
1905639	positive regulation of mitochondrial mRNA catabolic process	P	Any process that activates or increases the frequency, rate or extent of mitochondrial mRNA catabolic process.
1905640	response to acetaldehyde	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acetaldehyde stimulus.
1905641	cellular response to acetaldehyde	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an acetaldehyde stimulus.
1905642	negative regulation of DNA methylation	P	Any process that stops, prevents or reduces the frequency, rate or extent of DNA methylation.
1905643	positive regulation of DNA methylation	P	Any process that activates or increases the frequency, rate or extent of DNA methylation.
1905644	regulation of FACT complex assembly	P	Any process that modulates the frequency, rate or extent of FACT complex assembly.
1905645	negative regulation of FACT complex assembly	P	Any process that stops, prevents or reduces the frequency, rate or extent of FACT complex assembly.
1905646	positive regulation of FACT complex assembly	P	Any process that activates or increases the frequency, rate or extent of FACT complex assembly.
1905647	proline import across plasma membrane	P	The directed movement of proline from outside of a cell into the cytoplasmic compartment.
1905648	regulation of shell calcification	P	Any process that modulates the frequency, rate or extent of shell calcification.
1905649	negative regulation of shell calcification	P	Any process that stops, prevents or reduces the frequency, rate or extent of shell calcification.
1905650	positive regulation of shell calcification	P	Any process that activates or increases the frequency, rate or extent of shell calcification.
1905651	regulation of artery morphogenesis	P	Any process that modulates the frequency, rate or extent of artery morphogenesis.
1905652	negative regulation of artery morphogenesis	P	Any process that stops, prevents or reduces the frequency, rate or extent of artery morphogenesis.
1905653	positive regulation of artery morphogenesis	P	Any process that activates or increases the frequency, rate or extent of artery morphogenesis.
1905654	regulation of artery smooth muscle contraction	P	Any process that modulates the frequency, rate or extent of artery smooth muscle contraction.
1905655	negative regulation of artery smooth muscle contraction	P	Any process that stops, prevents or reduces the frequency, rate or extent of artery smooth muscle contraction.
1905656	positive regulation of artery smooth muscle contraction	P	Any process that activates or increases the frequency, rate or extent of artery smooth muscle contraction.
1905657	regulation of relaxation of vascular smooth muscle	P	Any process that modulates the frequency, rate or extent of relaxation of vascular smooth muscle.
1905658	negative regulation of relaxation of vascular smooth muscle	P	Any process that stops, prevents or reduces the frequency, rate or extent of relaxation of vascular smooth muscle.
1905659	positive regulation of relaxation of vascular smooth muscle	P	Any process that activates or increases the frequency, rate or extent of relaxation of vascular smooth muscle.
1905660	mitotic checkpoint complex assembly	P	The aggregation, arrangement and bonding together of a set of components to form a mitotic checkpoint complex.
1905661	regulation of telomerase RNA reverse transcriptase activity	P	Any process that modulates the frequency, rate or extent of telomerase RNA reverse transcriptase activity.
1905662	negative regulation of telomerase RNA reverse transcriptase activity	P	Any process that stops, prevents or reduces the frequency, rate or extent of telomerase RNA reverse transcriptase activity.
1905663	positive regulation of telomerase RNA reverse transcriptase activity	P	Any process that activates or increases the frequency, rate or extent of telomerase RNA reverse transcriptase activity.
1905664	regulation of calcium ion import across plasma membrane	P	Any process that modulates the frequency, rate or extent of calcium ion import across plasma membrane.
1905665	positive regulation of calcium ion import across plasma membrane	P	Any process that activates or increases the frequency, rate or extent of calcium ion import across plasma membrane.
1905666	regulation of protein localization to endosome	P	Any process that modulates the frequency, rate or extent of protein localization to endosome.
1905667	negative regulation of protein localization to endosome	P	Any process that stops, prevents or reduces the frequency, rate or extent of protein localization to endosome.
1905668	positive regulation of protein localization to endosome	P	Any process that activates or increases the frequency, rate or extent of protein localization to endosome.
1905669	TORC1 complex assembly	P	The aggregation, arrangement and bonding together of a set of components to form a TORC1 complex.
1905670	TORC2 complex disassembly	P	The disaggregation of a TORC2 complex into its constituent components.
1905671	regulation of lysosome organization	P	Any process that modulates the frequency, rate or extent of lysosome organization.
1905672	negative regulation of lysosome organization	P	Any process that stops, prevents or reduces the frequency, rate or extent of lysosome organization.
1905673	positive regulation of lysosome organization	P	Any process that activates or increases the frequency, rate or extent of lysosome organization.
1905674	regulation of adaptive immune memory response	P	Any process that modulates the frequency, rate or extent of adaptive immune memory response.
1905675	negative regulation of adaptive immune memory response	P	Any process that stops, prevents or reduces the frequency, rate or extent of adaptive immune memory response.
1905676	positive regulation of adaptive immune memory response	P	Any process that activates or increases the frequency, rate or extent of adaptive immune memory response.
1905677	regulation of adaptive immune effector response	P	Any process that modulates the frequency, rate or extent of adaptive immune effector response.
1905678	negative regulation of adaptive immune effector response	P	Any process that stops, prevents or reduces the frequency, rate or extent of adaptive immune effector response.
1905679	positive regulation of adaptive immune effector response	P	Any process that activates or increases the frequency, rate or extent of adaptive immune effector response.
1905680	regulation of innate immunity memory response	P	Any process that modulates the frequency, rate or extent of innate immunity memory response.
1905681	negative regulation of innate immunity memory response	P	Any process that stops, prevents or reduces the frequency, rate or extent of innate immunity memory response.
1905682	positive regulation of innate immunity memory response	P	Any process that activates or increases the frequency, rate or extent of innate immunity memory response.
1905683	peroxisome disassembly	P	The disaggregation of a peroxisome into its constituent components.
1905684	regulation of plasma membrane repair	P	Any process that modulates the frequency, rate or extent of plasma membrane repair.
1905685	negative regulation of plasma membrane repair	P	Any process that stops, prevents or reduces the frequency, rate or extent of plasma membrane repair.
1905686	positive regulation of plasma membrane repair	P	Any process that activates or increases the frequency, rate or extent of plasma membrane repair.
1905687	regulation of diacylglycerol kinase activity	P	Any process that modulates the frequency, rate or extent of diacylglycerol kinase activity.
1905688	negative regulation of diacylglycerol kinase activity	P	Any process that stops, prevents or reduces the frequency, rate or extent of diacylglycerol kinase activity.
1905689	positive regulation of diacylglycerol kinase activity	P	Any process that activates or increases the frequency, rate or extent of diacylglycerol kinase activity.
1905690	nucleus disassembly	P	The disaggregation of a nucleus into its constituent components.
1905691	lipid particle disassembly	P	The disaggregation of a lipid particle into its constituent components.
1905692	endoplasmic reticulum disassembly	P	The disaggregation of an endoplasmic reticulum into its constituent components.
1905693	regulation of phosphatidic acid biosynthetic process	P	Any process that modulates the frequency, rate or extent of phosphatidic acid biosynthetic process.
1905694	negative regulation of phosphatidic acid biosynthetic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of phosphatidic acid biosynthetic process.
1905695	positive regulation of phosphatidic acid biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of phosphatidic acid biosynthetic process.
1905696	regulation of polysome binding	P	Any process that modulates the frequency, rate or extent of polysome binding.
1905697	negative regulation of polysome binding	P	Any process that stops, prevents or reduces the frequency, rate or extent of polysome binding.
1905698	positive regulation of polysome binding	P	Any process that activates or increases the frequency, rate or extent of polysome binding.
1905699	regulation of drug transmembrane export	P	Any process that modulates the frequency, rate or extent of drug transmembrane export.
1905700	negative regulation of drug transmembrane export	P	Any process that stops, prevents or reduces the frequency, rate or extent of drug transmembrane export.
1905701	positive regulation of drug transmembrane export	P	Any process that activates or increases the frequency, rate or extent of drug transmembrane export.
1905702	regulation of inhibitory synapse assembly	P	Any process that modulates the frequency, rate or extent of inhibitory synapse assembly.
1905703	negative regulation of inhibitory synapse assembly	P	Any process that stops, prevents or reduces the frequency, rate or extent of inhibitory synapse assembly.
1905704	positive regulation of inhibitory synapse assembly	P	Any process that activates or increases the frequency, rate or extent of inhibitory synapse assembly.
1905705	cellular response to paclitaxel	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a paclitaxel stimulus.
1905706	regulation of mitochondrial ATP synthesis coupled proton transport	P	Any process that modulates the frequency, rate or extent of mitochondrial ATP synthesis coupled proton transport.
1905707	negative regulation of mitochondrial ATP synthesis coupled proton transport	P	Any process that stops, prevents or reduces the frequency, rate or extent of mitochondrial ATP synthesis coupled proton transport.
1905708	regulation of cell morphogenesis involved in conjugation with cellular fusion	P	Any process that modulates the location, frequency, rate or extent of cell morphogenesis involved in conjugation with cellular fusion.
1905709	negative regulation of membrane permeability	P	Any process that stops, prevents or reduces the frequency, rate or extent of the passage or uptake of molecules by a membrane.
1905710	positive regulation of membrane permeability	P	Any process that activates or increases the frequency, rate or extent of the passage or uptake of molecules by a membrane.
1905711	response to phosphatidylethanolamine	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a phosphatidylethanolamine stimulus.
1905712	cellular response to phosphatidylethanolamine	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a phosphatidylethanolamine stimulus.
1905715	regulation of cornification	P	Any process that modulates the frequency, rate or extent of cornification.
1905716	negative regulation of cornification	P	Any process that stops, prevents or reduces the frequency, rate or extent of cornification.
1905717	positive regulation of cornification	P	Any process that activates or increases the frequency, rate or extent of cornification.
1905719	protein localization to perinuclear region of cytoplasm	P	A process in which a protein is transported to, or maintained in, a location within the perinuclear region of the cytoplasm.
1905720	cytoplasmic microtubule bundle	C	Any microtubule bundle that is part of a cytoplasm.
1905721	mitotic spindle astral microtubule end	C	Any microtubule end that is part of a mitotic spindle astral microtubule.
1905722	regulation of trypanothione biosynthetic process	P	Any process that modulates the frequency, rate or extent of trypanothione biosynthetic process.
1905723	negative regulation of trypanothione biosynthetic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of trypanothione biosynthetic process.
1905724	positive regulation of trypanothione biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of trypanothione biosynthetic process.
1905725	protein localization to microtubule end	P	A process in which a protein is transported to, or maintained in, a location at a microtubule end.
1905735	regulation of L-proline import across plasma membrane	P	Any process that modulates the frequency, rate or extent of L-proline import across plasma membrane.
1905736	negative regulation of L-proline import across plasma membrane	P	Any process that stops, prevents or reduces the frequency, rate or extent of L-proline import across plasma membrane.
1905737	positive regulation of L-proline import across plasma membrane	P	Any process that activates or increases the frequency, rate or extent of L-proline import across plasma membrane.
1905741	mitochondrial calcium release involved in positive regulation of presynaptic cytosolic calcium concentration	P	Any mitochondrial calcium release that is involved in positive regulation of presynaptic cytosolic calcium concentration.
1905742	Ras guanyl-nucleotide exchange factor complex	C	A protein complex which is capable of Ras guanyl-nucleotide exchange factor activity.
1905743	mitochondrial calcium uptake involved in negative regulation of presynaptic cytosolic calcium concentration	P	Any mitochondrial calcium uptake that is involved in negative regulation of presynaptic cytosolic calcium concentration.
1905744	regulation of mRNA cis splicing, via spliceosome	P	Any process that modulates the frequency, rate or extent of mRNA cis splicing, via spliceosome.
1905745	negative regulation of mRNA cis splicing, via spliceosome	P	Any process that stops, prevents or reduces the frequency, rate or extent of mRNA cis splicing, via spliceosome.
1905746	positive regulation of mRNA cis splicing, via spliceosome	P	Any process that activates or increases the frequency, rate or extent of mRNA cis splicing, via spliceosome.
1905747	negative regulation of saliva secretion	P	Any process that stops, prevents or reduces the frequency, rate or extent of saliva secretion.
1905748	hard palate morphogenesis	P	The developmental process by which a hard palate is generated and organized.
1905749	regulation of endosome to plasma membrane protein transport	P	Any process that modulates the frequency, rate or extent of endosome to plasma membrane protein transport.
1905750	negative regulation of endosome to plasma membrane protein transport	P	Any process that stops, prevents or reduces the frequency, rate or extent of endosome to plasma membrane protein transport.
1905751	positive regulation of endosome to plasma membrane protein transport	P	Any process that activates or increases the frequency, rate or extent of endosome to plasma membrane protein transport.
1905752	regulation of argininosuccinate synthase activity	P	Any process that modulates the frequency, rate or extent of argininosuccinate synthase activity.
1905753	positive regulation of argininosuccinate synthase activity	P	Any process that activates or increases the frequency, rate or extent of argininosuccinate synthase activity.
1905754	ascospore-type prospore nucleus	C	Any nucleus that is part of a ascospore-type prospore.
1905755	protein localization to cytoplasmic microtubule	P	A process in which a protein is transported to, or maintained in, a location within a cytoplasmic microtubule.
1905756	regulation of primary cell septum biogenesis	P	Any process that modulates the frequency, rate or extent of primary cell septum biogenesis.
1905757	negative regulation of primary cell septum biogenesis	P	Any process that stops, prevents or reduces the frequency, rate or extent of primary cell septum biogenesis.
1905758	positive regulation of primary cell septum biogenesis	P	Any process that activates or increases the frequency, rate or extent of primary cell septum biogenesis.
1905759	post-anaphase array microtubule	C	Any microtubule that is part of a post-anaphase microtubule array.
1905760	post-anaphase array microtubule end	C	Any microtubule end that is part of a post-anaphase array microtubule.
1905761	SCF ubiquitin ligase complex binding	F	Interacting selectively and non-covalently with a SCF ubiquitin ligase complex.
1905762	CCR4-NOT complex binding	F	Interacting selectively and non-covalently with a CCR4-NOT complex.
1905763	MTREC complex binding	F	Interacting selectively and non-covalently with a MTREC complex.
1905764	regulation of protection from non-homologous end joining at telomere	P	Any process that modulates the frequency, rate or extent of protection from non-homologous end joining at telomere.
1905765	negative regulation of protection from non-homologous end joining at telomere	P	Any process that stops, prevents or reduces the frequency, rate or extent of protection from non-homologous end joining at telomere.
1905766	positive regulation of protection from non-homologous end joining at telomere	P	Any process that activates or increases the frequency, rate or extent of protection from non-homologous end joining at telomere.
1905767	regulation of double-stranded telomeric DNA binding	P	Any process that modulates the frequency, rate or extent of double-stranded telomeric DNA binding.
1905768	negative regulation of double-stranded telomeric DNA binding	P	Any process that stops, prevents or reduces the frequency, rate or extent of double-stranded telomeric DNA binding.
1905769	positive regulation of double-stranded telomeric DNA binding	P	Any process that activates or increases the frequency, rate or extent of double-stranded telomeric DNA binding.
1905770	regulation of mesodermal cell differentiation	P	Any process that modulates the frequency, rate or extent of mesodermal cell differentiation.
1905771	negative regulation of mesodermal cell differentiation	P	Any process that stops, prevents or reduces the frequency, rate or extent of mesodermal cell differentiation.
1905772	positive regulation of mesodermal cell differentiation	P	Any process that activates or increases the frequency, rate or extent of mesodermal cell differentiation.
1905773	8-hydroxy-2'-deoxyguanosine DNA binding	F	Interacting selectively and non-covalently with 8-hydroxy-2'-deoxyguanosine an oxidized purine residue found in damaged DNA.
1905774	regulation of DNA helicase activity	P	Any process that modulates the frequency, rate or extent of DNA helicase activity.
1905775	negative regulation of DNA helicase activity	P	Any process that stops, prevents or reduces the frequency, rate or extent of DNA helicase activity.
1905776	positive regulation of DNA helicase activity	P	Any process that activates or increases the frequency, rate or extent of DNA helicase activity.
1905777	regulation of exonuclease activity	P	Any process that modulates the frequency, rate or extent of exonuclease activity.
1905778	negative regulation of exonuclease activity	P	Any process that stops, prevents or reduces the frequency, rate or extent of exonuclease activity.
1905779	positive regulation of exonuclease activity	P	Any process that activates or increases the frequency, rate or extent of exonuclease activity.
1905780	regulation of phosphatidylserine exposure on apoptotic cell surface	P	Any process that modulates the frequency, rate or extent of phosphatidylserine exposure on apoptotic cell surface.
1905781	negative regulation of phosphatidylserine exposure on apoptotic cell surface	P	Any process that stops, prevents or reduces the frequency, rate or extent of phosphatidylserine exposure on apoptotic cell surface.
1905782	positive regulation of phosphatidylserine exposure on apoptotic cell surface	P	Any process that activates or increases the frequency, rate or extent of phosphatidylserine exposure on apoptotic cell surface.
1905783	CENP-A containing nucleosome disassembly	P	The disaggregation of a CENP-A containing nucleosome into its constituent components.
1905784	regulation of anaphase-promoting complex-dependent catabolic process	P	Any process that modulates the frequency, rate or extent of anaphase-promoting complex-dependent catabolic process.
1905785	negative regulation of anaphase-promoting complex-dependent catabolic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of anaphase-promoting complex-dependent catabolic process.
1905786	positive regulation of anaphase-promoting complex-dependent catabolic process	P	Any process that activates or increases the frequency, rate or extent of anaphase-promoting complex-dependent catabolic process.
1905787	regulation of detection of mechanical stimulus involved in sensory perception of touch	P	Any process that modulates the frequency, rate or extent of detection of mechanical stimulus involved in sensory perception of touch.
1905788	negative regulation of detection of mechanical stimulus involved in sensory perception of touch	P	Any process that stops, prevents or reduces the frequency, rate or extent of detection of mechanical stimulus involved in sensory perception of touch.
1905789	positive regulation of detection of mechanical stimulus involved in sensory perception of touch	P	Any process that activates or increases the frequency, rate or extent of detection of mechanical stimulus involved in sensory perception of touch.
1905790	regulation of mechanosensory behavior	P	Any process that modulates the frequency, rate or extent of mechanosensory behavior.
1905791	negative regulation of mechanosensory behavior	P	Any process that stops, prevents or reduces the frequency, rate or extent of mechanosensory behavior.
1905792	positive regulation of mechanosensory behavior	P	Any process that activates or increases the frequency, rate or extent of mechanosensory behavior.
1905793	protein localization to pericentriolar material	P	A process in which a protein is transported to, or maintained in, a location within a pericentriolar material.
1905794	response to puromycin	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a puromycin stimulus.
1905795	cellular response to puromycin	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a puromycin stimulus.
1905796	regulation of intraciliary anterograde transport	P	Any process that modulates the frequency, rate or extent of intraciliary anterograde transport.
1905797	negative regulation of intraciliary anterograde transport	P	Any process that stops, prevents or reduces the frequency, rate or extent of intraciliary anterograde transport.
1905798	positive regulation of intraciliary anterograde transport	P	Any process that activates or increases the frequency, rate or extent of intraciliary anterograde transport.
1905799	regulation of intraciliary retrograde transport	P	Any process that modulates the frequency, rate or extent of intraciliary retrograde transport.
1905800	negative regulation of intraciliary retrograde transport	P	Any process that stops, prevents or reduces the frequency, rate or extent of intraciliary retrograde transport.
1905801	positive regulation of intraciliary retrograde transport	P	Any process that activates or increases the frequency, rate or extent of intraciliary retrograde transport.
1905802	regulation of cellular response to manganese ion	P	Any process that modulates the frequency, rate or extent of cellular response to manganese ion.
1905803	negative regulation of cellular response to manganese ion	P	Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to manganese ion.
1905804	positive regulation of cellular response to manganese ion	P	Any process that activates or increases the frequency, rate or extent of cellular response to manganese ion.
1905805	excitatory synapse disassembly	P	The disaggregation of an excitatory synapse into its constituent components.
1905806	regulation of synapse disassembly	P	Any process that modulates the frequency, rate or extent of synapse disassembly.
1905807	negative regulation of synapse disassembly	P	Any process that stops, prevents or reduces the frequency, rate or extent of synapse disassembly.
1905808	positive regulation of synapse disassembly	P	Any process that activates or increases the frequency, rate or extent of synapse disassembly.
1905809	negative regulation of synapse organization	P	Any process that stops, prevents or reduces the frequency, rate or extent of synapse organization.
1905810	regulation of excitatory synapse disassembly	P	Any process that modulates the frequency, rate or extent of excitatory synapse disassembly.
1905811	negative regulation of excitatory synapse disassembly	P	Any process that stops, prevents or reduces the frequency, rate or extent of excitatory synapse disassembly.
1990000	amyloid fibril formation	P	The generation of amyloid fibrils, insoluble fibrous protein aggregates exhibiting beta sheet structure, from proteins. An example of this is seen when human RIP1 and RIP3 kinases form a heterodimeric functional amyloid signaling complex (PMID:22817896).
1990001	inhibition of cysteine-type endopeptidase activity involved in apoptotic process	P	Any process that prevents the activation of an inactive cysteine-type endopeptidase involved in an apoptotic process.
1990002	methylglyoxal reductase (NADPH-dependent, acetol producing)	F	Catalysis of the reaction: H+ + methylglyoxal + NADPH <=> hydroxyacetone + NADP+.
1990003	IDP phosphatase activity	F	Catalysis of the reaction: IDP + H2O = IMP + phosphate.
1990004	XDP phosphatase activity	F	Catalysis of the reaction: XDP + H2O = XMP + phosphate.
1990005	granular vesicle	C	A cytoplasmic membrane-bounded vesicle of varying size, but usually larger than 45 nm, with an electron dense granular core, found in noradrenergic and peptidergic cells.
1990006	amorphous vesicle	C	A cytoplasmic membrane-bounded vesicle first described in dendrites, categorized by smooth membranes, electron-lucent interiors and irregular shapes. Sometimes occurs in clumps. Amorphous vesicles have been found to contain material taken up from the extracellular space, therefore suggesting that they may be part of the endosomal pathway.
1990007	membrane stack	C	A configuration of endoplasmic reticulum (ER) found in Purkinje cells in the cerebellum and in axons in the lateral vestibular nucleus, consisting of parallel and interconnecting tubules whose outer surfaces are covered by particles or ringlike structures.
1990008	neurosecretory vesicle	C	A large cytoplasmic membrane-bounded vesicle with an electron dense granular core, up to 150-200 nm in diameter, found in neurosecretory cells in the hypothalamus.
1990009	retinal cell apoptotic process	P	Any apoptotic process in a retinal cell.
1990010	compound eye retinal cell apoptotic process	P	Any apoptotic process in a compound eye retinal cell.
1990011	laminated body	C	Inclusion body characterized by regularly spaced sheets of tubules arranged in a whorl pattern resembling a fingerprint. Laminated bodies have been observed in neurons of the lateral geniculate nucleus.
1990012	complex laminated body	C	A cytoplasmic inclusion body found in some lateral geniculate neurons and composed of sheets of tubules (25 nm in diameter) separated by dense material (about 75 nm wide), which together with the tubules whorl give a structure resembling a fingerprint.
1990013	presynaptic grid	C	A hexagonal array of electron dense particles attached to the cytoplasmic face of the presynaptic membrane.
1990014	orthogonal array	C	Square array of closely spaced intramembrane particles, 4-6 nm in size, that form supramolecular aggregates found in the plasma membrane of astrocytes, skeletal muscle and epithelial cells. They have been shown to contain aquaporins (water channels).
1990015	ensheathing process	C	A cell projection (often from glial cells such as Schwann cells) that surrounds an unmyelinated axon or cell soma.
1990016	neck portion of tanycyte	C	Elongated portion of a tanycyte that sticks into the periventricular layer of neuropil where it appears to contact a blood vessel; characterized by numerous cytoplasmic extensions. A tanycyte is a specialized elongated ventricular ependymal cell that has processes that extend to the outer, or pial, surface of the CNS.
1990017	somatic portion of tanycyte	C	Portion of a tanycyte that lies within the ependyma and contains the nucleus. A tanycyte is a specialized elongated ventricular ependymal cell that has processes that extend to the outer, or pial, surface of the CNS.
1990018	tail portion of tanycyte	C	Elongated process of a tanycyte, devoid of cytoplasmic extensions, that courses through the hypothalamic nuclei to form small endfoot processes that terminate either on blood vessels or at the pial surface of the brain. A tanycyte is a specialized elongated ventricular ependymal cell.
1990019	protein storage vacuole organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a protein storage vacuole, a storage vacuole that contains a lytic vacuole.
1990020	recurrent axon collateral	C	Axon collateral that ramifies in the area of the soma of the cell of origin.
1990021	Schaffer axon collateral	C	Part of axon of a CA3 pyramidal neuron that projects to hippocampal area CA1.
1990022	RNA polymerase III complex localization to nucleus	P	The directed movement of an RNA polymerase III complex from the cytoplasm to the nucleus.
1990023	mitotic spindle midzone	C	The area in the center of the anaphase spindle consisting of microtubules, microtubule bundling factors and kinesin motors where the spindle microtubules from opposite poles overlap in an antiparallel manner.
1990024	C bouton	C	Synaptic bouton found in spinal cord on the soma and proximal dendrites of motor neurons.
1990025	F bouton	C	Synaptic bouton found in the ventral horn of the spinal cord. F boutons range in diameter from 0.5 to 7 um and contain flattened or pleomorphic synaptic vesicles.
1990026	hippocampal mossy fiber expansion	C	Synaptic expansion of hippocampal mossy fiber axon that makes contact with the thorny excrescences of hippocampal CA3 pyramidal cell dendrites.
1990027	S bouton	C	Synaptic bouton found in the ventral horn of the spinal cord. S boutons range in diameter from 0.5 to 8 um and contain spherical synaptic vesicles.
1990028	intermediate voltage-gated calcium channel activity	F	Enables the transmembrane transfer of a calcium ion by an intermediate voltage-gated channel. An intermediate voltage-gated channel is a channel whose open state is dependent on intermediate voltage across the membrane in which it is embedded.
1990029	vasomotion	P	The rhythmical contraction and relaxation of arterioles, observed as slow and fast waves, with frequencies of 1-2 and 10-20 cpm.
1990030	pericellular basket	C	Ramification of basket cell axon surrounding cell bodies, forming the characteristic pericellular baskets from which the cell class derives its name.
1990031	pinceau fiber	C	Dense plexus formed by the descending collaterals of cerebellar basket cells that wrap around a Purkinje cell axonal initial segment.
1990032	parallel fiber	C	A parallel fiber results from the bifurcation of a cerebellar granule cell axon in the molecular layer into two diametrically opposed branches, that are oriented parallel to the long axis of the folium.
1990033	dendritic branch point	C	The part of a dendrite where the cell projection branches, giving rise to a dendritic branch.
1990034	calcium ion export from cell	P	The directed movement of calcium ions out of a cell.
1990035	calcium ion import into cell	P	The directed movement of calcium ions from outside of a cell into the cytoplasmic compartment. This may occur via transport across the plasma membrane or via endocytosis.
1990036	calcium ion import into sarcoplasmic reticulum	P	The directed movement of calcium ions into a sarcoplasmic reticulum.
1990037	Lewy body core	C	The center portion of a Lewy body. In Parkinson's disease, it contains a matted meshwork of filaments.
1990038	Lewy body corona	C	The periphery of a Lewy body. In Parkinson's disease, it contains spherical accumulations of filaments arranged in a loose, radiating array.
1990039	hypolemmal cisterna	C	Specialized part of the smooth endoplasmic reticulum that closely underlies the plasma membrane, usually within 60 nm or closer.
1990040	sub-surface cisterna	C	Specialization of the hypolemmal cisterna consisting of either single profiles or closely apposed stacks of endoplasmic reticulum in which the lumen is obliterated, lying 10-20 nm beneath the plasma membrane.
1990042	glycerol dehydrogenase [NAD(P)+] activity	F	Catalysis of an oxidation-reduction (redox) reaction in which glycerol is converted into glycerone and NAD+ or NADP is reduced.
1990043	5' deoxyribonuclease (pyrimidine dimer) activity	F	Catalysis of the endonucleolytic cleavage immediately 5' to pyrimidine dimers to products with 5'-phosphate.
1990044	protein localization to lipid particle	P	A process in which a protein is transported to, or maintained in, a location on or within a lipid particle.
1990045	sclerotium development	P	The process whose specific outcome is the progression of the sclerotium over time, from its formation to the mature structure. A sclerotium is a mycelial resting body, resistant to adverse environmental conditions.
1990046	stress-induced mitochondrial fusion	P	Merging of two or more mitochondria within a cell to form a single compartment, as a result of a disturbance in cellular homeostasis.
1990047	spindle matrix	C	A proteinaceous, nuclear-derived structure that embeds the microtubule spindle apparatus from pole to pole in a microtubule-independent manner during mitosis.
1990048	anterograde neuronal dense core vesicle transport	P	The directed movement of substances in neuronal dense core vesicles along axonal microtubules towards the presynapse.
1990049	retrograde neuronal dense core vesicle transport	P	The directed movement of neuronal dense core vesicles along axonal microtubules towards the cell body.
1990050	phosphatidic acid transporter activity	F	Enables the directed movement of phosphatidic acid into, out of or within a cell, or between cells. Phosphatidic acid refers to a glycophospholipids with, in general, a saturated fatty acid bonded to carbon-1, an unsaturated fatty acid bonded to carbon-2, and a phosphate group bonded to carbon-3.
1990051	activation of protein kinase C activity	P	Any process that initiates the activity of the inactive enzyme protein kinase C.
1990052	ER to chloroplast lipid transport	P	The directed movement of a lipid from the endoplasmic reticulum (ER) to the chloroplast.
1990053	DNA-5-methylcytosine glycosylase activity	F	Catalysis of the reaction: DNA containing 5-methylcytosine + H2O = DNA with abasic site + 5-methylcytosine. This reaction is the hydrolysis of DNA by cleavage of the N-C1' glycosidic bond between the DNA 5-methylcytosine and the deoxyribose sugar to remove the 5-methylcytosine, leaving an abasic site.
1990054	response to temozolomide	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a temozolomide stimulus.
1990055	phenylacetaldehyde synthase activity	F	Catalyzes the reaction: L-phenylalanine + O2 + H2O -> phenylacetaldehyde + ammonia + hydrogen peroxide + CO2.
1990058	fruit replum development	P	The process whose specific outcome is the progression of the fruit replum over time, from its formation to the mature structure. The fruit replum is a portion of fruit placenta tissue that divides a fruit into two or more chambers and develops from a replum.
1990059	fruit valve development	P	The process whose specific outcome is the progression of the fruit valve over time, from its formation to the mature structure. The fruit valve is a part of a fruit that splits apart when the fruit dehisces.
1990060	maltose transport complex	C	Protein complex facilitating ATP-dependent maltose transport through inner cell membrane (periplasm to cytoplasm) in Gram-negative bacteria. In E. coli the system is composed of a periplasmic maltose-binding protein (MBP), two integral membrane proteins, MalF and MalG, and two copies of the cytoplasmic ATP-binding cassette MalK.
1990061	bacterial degradosome	C	The degradosome is a protein complex playing a key role in mRNA degradation and RNA processing. It includes a RNA helicase, a 3'-5' phosphate-dependent PNPase and a RNase E bound-enolase.
1990062	RPAP3/R2TP/prefoldin-like complex	C	A protein complex first characterized in human and comprised of a R2TP module (R2TP complex), a prefoldin-like module (containing both prefoldin-like proteins and canonical prefoldins), WD40 repeat protein Monad/WDR92 and DNA-dependent RNA polymerase subunit RPB5. This complex might have chaperone activity.
1990063	Bam protein complex	C	Protein complex which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. In E. coli it is composed of BamABCDE, of the outer membrane protein BamA, and four lipoproteins BamB, BamC, BamD and BamE. BamA interacts directly with BamB and the BamCDE subcomplex.
1990064	ground tissue pattern formation	P	The regionalization process that gives rise to the patterning of the ground tissue.
1990065	Dxr protein complex	C	A protein complex that is involved in the MEP pathway of IPP biosynthesis. It catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP).
1990066	energy quenching	P	The process by which excess light energy absorbed by chlorophyll and not used to drive photosynthesis is emitted by nonphotochemical quenching or chlorophyll fluorescence.
1990067	intrachromosomal DNA recombination	P	The process of DNA recombination occurring within a single chromosome.
1990068	seed dehydration	P	The seed development process whose outcome is the drying of a maturing seed.
1990069	stomatal opening	P	The process of opening of stomata, pores in the epidermis of leaves and stems bordered by two guard cells and serving in gas exchange.
1990070	TRAPPI protein complex	C	A complex that tethers COPII vesicles at ER-Golgi intermediate compartment. Its role in this part of the vesicular transport may start at the ER exit sites. Binds to a component of the COPII coat. In yeast it includes the following subunits: Bet3 (as homodimer), Bet5, Trs20, Trs23, Trs31, Trs33 which are regarded as the "core subunits" of all TRAPP complexes in yeast.
1990071	TRAPPII protein complex	C	A complex that mediates intra-Golgi traffic, Golgi exit, endosome-to-Golgi traffic, and the trafficking of autophagy proteins from Golgi to the pre-autophagosomal structure. Binds to a component of the COPI coat. In yeast it includes the following subunits: Bet3 (as homodimer), Bet5, Tca17, Trs20, Trs23, Trs31, Trs33, Trs65, Trs120, Trs130. The whole complex is thought to dimerize with itself.
1990072	TRAPPIII protein complex	C	A complex that functions in anterograde transport at the Golgi and also regulates autophagy. In yeast it includes at least the following subunits: Bet3 (as homodimer), Bet5, Trs20, Trs23, Trs31, Trs33, Trs85. TRAPPIII may include further, as yet undescribed, proteins.
1990073	perforation plate	C	A cell wall part that is the part of a wall of a vessel member and bears one or more openings (perforations).
1990074	polyuridylation-dependent mRNA catabolic process	P	The chemical reactions and pathways resulting in the breakdown of a messenger RNA (mRNA) molecule, initiated by the enzymatic addition of a sequence of uridylyl residues (polyuridylation) at the 3' end of the target mRNA.
1990075	periciliary membrane compartment	C	A plasma membrane region adjacent to the base of eukaryotic cilia and flagella that is enriched in endocytosis-associated proteins and vesicles and that appears to regulate ciliary membrane homeostasis.
1990076	cell wall polysaccharide catabolic process involved in abscission	P	Any cell wall polysaccharide catabolic process that is involved in abscission.
1990077	primosome complex	C	Any of a family of protein complexes that form at the origin of replication or stalled replication forks and function in replication primer synthesis in all organisms. Early complexes initiate double-stranded DNA unwinding. The core unit consists of a replicative helicase and a primase. The helicase further unwinds the DNA and recruits the polymerase machinery. The primase synthesizes RNA primers that act as templates for complementary stand replication by the polymerase machinery. The primosome contains a number of associated proteins and protein complexes and contributes to the processes of replication initiation, lagging strand elongation, and replication restart.
1990078	replication inhibiting complex	C	A protein complex that inhibits multiple events of replication initiation during one replication cycle.
1990079	cartilage homeostasis	P	A tissue homeostatic process involved in the maintenance of an internal equilibrium within cartilage, including control of cellular proliferation and death and control of metabolic function.
1990080	2-phenylethylamine receptor activity	F	Combining with the biogenic amine 2-phenylethylamine to initiate a change in cell activity.
1990081	trimethylamine receptor activity	F	Combining with the biogenic amine trimethylamine to initiate a change in cell activity.
1990082	DnaA-L2 complex	C	A protein complex that inhibits unwinding of DNA at the origin of replication and assembly of the pre-primosome. In E. coli, this complex is composed of DnaA and of the ribosomal protein L2.
1990083	DnaA-Hda complex	C	A protein complex that inactivates the function of DnaA by inhibiting the phosphorylation of DnaA-ADP to DnaA-ATP and thereby preventing multiple events of replication initiation. In E. coli, this complex is composed of DnaA and Hda.
1990084	DnaA-Dps complex	C	A protein complex that negatively regulates strand-opening at the origin of replication, thereby interfering with replication initiation. This complex is thought to be involved in the regulation of replication under oxidative stress conditions. In E. coli, this complex is composed of DnaA and Dps.
1990085	Hda-beta clamp complex	C	A protein complex involved in inactivating the function of DnaA and thereby preventing multiple events of replication initiation. In E. coli, this complex is composed of the beta clamp (DnaN) and Hda.
1990086	lens fiber cell apoptotic process	P	Any apoptotic process in a lens fiber cell. Lens fiber cells are elongated, tightly packed cells that make up the bulk of the mature lens in a camera-type eye.
1990088	[methyl-Co(III) methanol-specific corrinoid protein]:coenzyme M methyltransferase activity	F	Catalysis of the reaction: a [methyl-Co(III) methanol-specific corrinoid protein] + coenzyme M = methyl-CoM + a [Co(I) methanol-specific corrinoid protein].
1990089	response to nerve growth factor	P	A process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nerve growth factor stimulus.
1990090	cellular response to nerve growth factor stimulus	P	A process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nerve growth factor stimulus.
1990091	sodium-dependent self proteolysis	P	The sodium-dependent hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their own peptide bonds.
1990092	calcium-dependent self proteolysis	P	The calcium-dependent hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their own peptide bonds.
1990095	positive regulation of transcription from RNA polymerase II promoter in response to reactive oxygen species	P	Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a reactive oxygen species stimulus. Reactive oxygen species include singlet oxygen, superoxide, and oxygen free radicals.
1990096	positive regulation of transcription from RNA polymerase II promoter in response to superoxide	P	Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a superoxide stimulus. Superoxide is the anion, oxygen-, formed by addition of one electron to dioxygen (O2) or any compound containing the superoxide anion.
1990097	SeqA-DNA complex	C	A protein-DNA complex that contains an oligomer of SeqA bound to GATC sites in methylated or newly-synthesized, hemi-methylated double-stranded DNA, with preference for the latter. Binding of SeqA to hemimethylated DNA sequesters oriC, prevents re-methylation of DNA by Dam and in turn stops premature re-initiation of replication during one replication cycle.
1990098	core primosome complex	C	A protein-DNA complex containing at least one DNA helicase and one primase. Can also contain associated proteins. The helicase component continues to unwind the double-stranded DNA (dsDNA) and the primase component synthesizes a RNA primer during initiation or restart of replication.
1990099	pre-primosome complex	C	Any of the protein-DNA complexes that contain a DNA helicase and associated protein(s) at the origin of replication, and build up to assembling the core primosome. The associated protein(s) chaperone the helicase to the DNA, and assembly of the pre-primosome is essential for the initiation or restart of replication. Pre-primosome complexes lack a primase component.
1990100	DnaB-DnaC complex	C	A protein complex containing homohexameric DNA helicase DnaB, and the DNA helicase loader DnaC. The helicase loader DnaC delivers DnaB to the chromosomal origin (oriC).
1990101	DnaA-oriC complex	C	A protein-DNA complex containing the initiator protein DnaA bound to high-affinity recognition sites in the unique origin of replication, oriC. DnaA-oriC binding is the first step in assembly of a bacterial pre-replicative complex (pre-RC) and is responsible for the timely initiation of replication once per cell cycle.
1990102	DnaA-DiaA complex	C	A protein-DNA complex containing a tetramer of DiaA attached to multiple DnaA molecule bound to oriC DNA. Regulates timely initiation of chromosomal replication during the cell cycle by stimulating assembly of DnaA-oriC complexes, conformational changes in ATP-DnaA initiation complexes, and unwinding of oriC duplex DNA.
1990103	DnaA-HU complex	C	A protein-DNA complex containing DNA-bound DnaA attached to HU. HU is a dimer encoded by two closely related genes. Essential for the initiation of replication in bacteria; stimulates the DnaA-dependent unwinding of oriC.
1990104	DNA bending complex	C	A protein-DNA complex that contains DNA in combination with a protein which binds to and bends DNA. Often plays a role in DNA compaction.
1990107	thiazole synthase activity	F	Catalysis of the reaction: 1-deoxy-D-xylulose 5-phosphate + 2-iminoacetate + thiocarboxy-adenylate-[sulfur-carrier protein ThiS] = 2-[(2R,5Z)-2-carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate + [sulfur-carrier protein ThiS] + 2 H2O.
1990108	protein linear deubiquitination	P	A protein deubiquitination process in which a linear polymer of ubiquitin, formed by the amino-terminal methionine (M1) of one ubiquitin molecule and by the carboxy-terminal glycine (G76) of the next, is removed from a protein.
1990109	rejection of pollen from other species	P	The process involved in the rejection of pollen of one species by cells in the stigma of another species.
1990110	callus formation	P	The process by which a callus is formed at a wound site. A plant callus is a portion of plant tissue that consists of mass of undifferentiated plant cells. It consists primarily of parenchyma cells but possibly contains other cell types as the callus begins to differentiate.
1990111	spermatoproteasome complex	C	A proteasome specifically found in mammalian testis. Contains the proteasome activator PA200 in the regulatory particle, and beta1i, beta2i, beta5i and/or alpha4s in the core (20S) subunit. Beta1i, beta2i and beta5i are inducible catalytic subunits, closely related to beta1, beta2 and beta5. Alpha4s is a sperm-specific 20S subunit, but unlike other alternative 20S subunits alpha4s lies in the outer alpha-ring and lacks catalytic activity.
1990112	RQC complex	C	A multiprotein complex that forms a stable complex with 60S ribosomal subunits containing stalled polypeptides and triggers their degradation (ribosomal quality control). In budding yeast, this complex includes Cdc48p, Rkr1p, Tae2p, Rqc1p, Npl4p and Ufd1p proteins.
1990113	RNA Polymerase I assembly	P	The aggregation, arrangement and bonding together of a set of components to form the eukaryotic RNA polymerase I complex.
1990114	RNA Polymerase II core complex assembly	P	The aggregation, arrangement and bonding together of a set of components to form the eukaryotic RNA polymerase II core complex.
1990115	RNA Polymerase III assembly	P	The aggregation, arrangement and bonding together of a set of components to form the eukaryotic RNA polymerase III complex.
1990116	ribosome-associated ubiquitin-dependent protein catabolic process	P	The chemical reactions and pathways resulting in the breakdown of a protein or peptide encoded by an aberrant message and associated with a stalled ribosome. Degradation is initiated by the covalent attachment of a ubiquitin group, or multiple ubiquitin groups, to the ribosome-associated protein.
1990117	B cell receptor apoptotic signaling pathway	P	An extrinsic apoptotic signaling pathway initiated by the cross-linking of an antigen receptor on a B cell.
1990118	sodium ion import into cell	P	The directed movement of sodium ions from outside of a cell into the intracellular region of a cell.
1990119	ATP-dependent RNA helicase inhibitor activity	F	Stops, prevents or reduces the activity of ATP-dependent RNA helicase.
1990120	messenger ribonucleoprotein complex assembly	P	The aggregation, arrangement and bonding together of proteins and messenger RNA (mRNA) molecules to form a messenger ribonucleoprotein (mRNP) complex.
1990121	H-NS complex	C	A multimer of H-NS proteins that is involved in bacterial nucleoid condensation and negative regulation of global gene expression by directly binding to promoter regions. Recognizes both structural and sequence-specific motifs in double-stranded DNA and has binding preference for bent DNA.
1990122	leucine import into cell	P	The directed movement of leucine from outside of a cell into the cytoplasmic compartment. This may occur via transport across the plasma membrane or via endocytosis.
1990123	L-glutamate import into cell	P	The directed movement of L-glutamate from outside of a cell into the cytoplasmic compartment. This may occur via transport across the plasma membrane or via endocytosis.
1990124	messenger ribonucleoprotein complex	C	A ribonucleoprotein complex containing both protein and messenger RNA (mRNA) molecules.
1990125	DiaA complex	C	A homotetrameric protein complex consisting of a symmetrical pair of DiaA homodimers. Facilitates DnaA binding to the origin of replication during replication initiation.
1990126	retrograde transport, endosome to plasma membrane	P	The directed movement of membrane-bounded vesicles from endosomes back to the plasma membrane, a trafficking pathway that promotes the recycling of internalized transmembrane proteins.
1990127	intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator	P	A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of osmotic stress, and ends when the execution phase of apoptosis is triggered.
1990130	Iml1 complex	C	A protein complex involved in regulation of non-nitrogen-starvation (NNS) autophagic process. In S. cerevisiae this complex contains Iml1p, Npr2p and Npr3p proteins. In humans the GATOR1 complex consists of DEPDC5, Nprl2, Nprl3.
1990131	Gtr1-Gtr2 GTPase complex	C	A heterodimer GTPase complex. In S. cerevisiae, this complex contains Gtr1p and Gtr2p proteins.
1990133	molybdopterin cofactor (Moco) biosynthesis adenylyltransferase complex	C	A heterodimeric protein complex which adenylates two molecules of the sulfur carrier subunit of the molybdopterin (MPT) cofactor synthase using ATP as part of molybdopterin cofactor (Moco) biosynthesis. In E. coli the subunits are MoeB and MoaD; Moco biosynthesis and its constituent molecules are evolutionarily conserved.
1990134	epithelial cell apoptotic process involved in palatal shelf morphogenesis	P	An apoptotic process in a palatal shelf epithelial cell that contributes to the shaping of the palatal shelf.
1990135	flavonoid sulfotransferase activity	F	Catalysis of the reaction: a flavonoid + 3'-phosphoadenosine-5'-phosphosulfate = sulfated flavonoid + adenosine-3',5'-diphosphate. This reaction is the transfer of a sulfate group to the hydroxyl group of a flavonoid acceptor, producing the sulfated flavonoid derivative.
1990136	linoleate 9S-lipoxygenase activity	F	Catalysis of the reaction: linoleate + O2 = (9S,10E,12Z)-9-hydroperoxy-10,12-octadecadienoate.
1990137	plant seed peroxidase activity	F	Catalysis of the reaction: R1H + R2OOH = R1OH + R2OH.
1990138	neuron projection extension	P	Long distance growth of a single neuron projection involved in cellular development. A neuron projection is a prolongation or process extending from a nerve cell, e.g. an axon or dendrite.
1990139	protein localization to nuclear periphery	P	A process in which a protein is transported to, or maintained in, a location within the nuclear periphery.
1990140	MPT synthase complex	C	A heterodimeric protein complex which catalyses sulfur transfer from the sulfur carrier subunit of MPT synthase to precursor Z to synthesize MPT as part of molybdopterin cofactor (Moco) biosynthesis. In E. coli the subunits are MoaE and MoaD; in human, MOCS2B and MOCS2A. Moco biosynthesis and its constituent molecules are evolutionarily conserved.
1990141	chromatin silencing at centromere outer repeat region	P	Repression of transcription of DNA at the outer repeat region of a regional centromere by altering the structure of chromatin.
1990142	envenomation resulting in hemolysis in other organism	P	A process that begins with venom being forced into an organism by the bite or sting of another organism, and ends with hemolysis in the bitten organism.
1990143	CoA-synthesizing protein complex	C	A multisubunit complex likely involved in the synthesis of coenzyme A (CoA). In S. cerevisiae, the complex consists of at least Cab2, Cab3, Cab4 and Cab5 but may also include Sis2 and Vhs3. The latter subunits are shared by the GO:0071513 phosphopantothenoylcysteine decarboxylase complex that catalyses the third step of the coenzyme A (CoA) biosynthetic pathway.
1990144	intrinsic apoptotic signaling pathway in response to hypoxia	P	A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced in response to hypoxia (lowered oxygen tension). Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level. The pathway ends when the execution phase of apoptosis is triggered.
1990145	maintenance of translational fidelity	P	Suppression of the occurrence of translational errors, such as codon-anticodon mis-paring, during the process of translation of a protein using an mRNA template.
1990146	protein localization to rhabdomere	P	A process in which a protein is transported to, or maintained in, a location within a rhabdomere.
1990147	talin binding	F	Interacting selectively and non-covalently with a talin, a family of related cytoskeletal proteins that play a role in assembly of actin filaments and migration of various cell types.
1990148	glutamate dehydrogenase complex	C	A homomeric protein complex that possesses glutamate dehydrogenase activity. This complex is evolutionarily conserved except that the number of homoprotomers per complex varies.
1990150	VEGF-A complex	C	A homodimeric, extracellular protein complex containing two VEGF-A monomers. Binds to and activates a receptor tyrosine kinase.
1990151	protein localization to cell tip	P	A process in which a protein is transported to, or maintained in, a location at the cell tip.
1990152	protein localization to telomeric heterochromatin	P	A process in which a protein is transported to, or maintained in, a location in telomeric heterochromatin.
1990153	maintenance of protein localization to heterochromatin	P	A process in which a protein is maintained in a location in telomeric heterochromatin.
1990154	enzyme IIA-maltose transporter complex	C	A protein complex consisting of the pentameric maltose transporter complex bound to two enzyme IIA (EIIA) molecules. EIIA is a component of the glucose-specific phosphotransferase system that inhibits maltose transport from the periplasm to the cytoplasm. When EIIA-bound, the maltose transporter remains in the open, inward-facing conformation, which prevents binding of maltose-loaded maltose binding protein (MBP) to the transporter.
1990155	Dsc E3 ubiquitin ligase complex assembly	P	The aggregation, arrangement and bonding together of a set of components to form a Dsc E3 ubiquitin ligase complex, an E3 ubiquitin ligase complex localized to the ER and Golgi membrane.
1990156	DnaB-DnaG complex	C	A protein complex containing homohexameric DnaB helicase, and DnaG (a primase). Facilitates the unwinding of double-stranded DNA and the synthesis of RNA primer sequences during DNA replication and repair in Prokaryotes.
1990157	DnaA-DnaB-DnaC complex	C	A protein-DNA complex consisting of the helicase loading complex DnaB-DnaC bound to the DNA-bound DNA replication initiation protein DnaA. Essential for DNA replication initiation.
1990158	DnaB-DnaC-DnaT-PriA-PriB complex	C	A protein-DNA complex consisting of the helicase loading complex DnaB-DnaC, replication restart proteins DnaT, PriA and PriB, and associated DNA. Involved in the restart of DNA replication after a stalled replication fork has been repaired.
1990159	DnaB-DnaC-DnaT-PriA-PriC complex	C	A protein-DNA complex consisting of the helicase loading complex DnaB-DnaC, replication restart proteins DnaT, PriA and PriC, and associated DNA. Involved in the restart of DNA replication after a stalled replication fork has been repaired.
1990160	DnaB-DnaC-Rep-PriC complex	C	A protein-DNA complex consisting of the helicase loading complex DnaB-DnaC, replication restart proteins Rep and PriC, and associated DNA. Involved in the restart of DNA replication after a stalled replication fork has been repaired.
1990161	DnaB helicase complex	C	A homohexameric protein complex that possesses DNA helicase activity; functions during DNA replication and repair.
1990162	histone deacetylase activity (H3-K4 specific)	F	Catalysis of the reaction: histone H3 N6-acetyl-L-lysine (position 4) + H2O = histone H3 L-lysine (position 4) + acetate. This reaction represents the removal of an acetyl group from lysine at position 4 of the histone H3 protein.
1990163	ATP-dependent four-way junction helicase activity	F	Catalysis of the reaction: ATP + H2O = ADP + phosphate, where this reaction drives the unwinding of the DNA helix of DNA containing four-way junctions, including Holliday junctions.
1990164	histone H2A phosphorylation	P	The modification of histone H2A by the addition of a phosphate group.
1990165	single-strand break-containing DNA binding	F	Interacting selectively and non-covalently with damaged DNA containing single-strand breaks (SSBs).
1990166	protein localization to site of double-strand break	P	Any process in which a protein is transported to, or maintained at, a region of a chromosome at which a DNA double-strand break has occurred.
1990167	protein K27-linked deubiquitination	P	A protein deubiquitination process in which a K27-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 27 of the ubiquitin monomers, is removed from a protein.
1990168	protein K33-linked deubiquitination	P	A protein deubiquitination process in which a K33-linked ubiquitin chain, i.e. a polymer of ubiquitin formed by linkages between lysine residues at position 33 of the ubiquitin monomers, is removed from a protein.
1990169	stress response to copper ion	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis caused by a copper ion stimulus.
1990170	stress response to cadmium ion	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis caused by a cadmium ion stimulus.
1990171	SCF complex disassembly in response to cadmium stress	P	The disaggregation of the SCF ubiquitin ligase complex in response to cadmium stress.
1990172	G-protein coupled receptor catabolic process	P	The chemical reactions and pathways resulting in the breakdown of a G-protein coupled receptor.
1990173	protein localization to nucleoplasm	P	A process in which a protein is transported to, or maintained in, a location within the nucleoplasm.
1990174	phosphodiesterase decapping endonuclease activity	F	Catalysis of the removal of the cap from an unmethylated 5'-end capped RNA resulting in the release of the entire cap structure (GpppN) and a 5' monophosphorylated RNA.
1990175	EH domain binding	F	Interacting selectively and non-covalently with an EH domain of a protein. The EH stand for Eps15 homology. This was originally identified as a motif present in three copies at the NH2-termini of Eps15 and of the related molecule Eps15R.
1990176	MalFGK2 complex	C	Protein complex involved in maltose transport through the plasma membrane. In E. coli, the complex is a tetramer and consists of a cytoplasmic ATPase MalK homodimer together with a heterodimeric transmembrane subunit MalF-MalG.
1990177	IHF-DNA complex	C	A protein-DNA complex containing IHF heterodimers (an alpha and a beta chain) bound to DNA. IHF binds to double-stranded DNA in a structure- and sequence-specific manner and bends the DNA into a nucleosome-like structure, the bacterial nucleoid.
1990178	HU-DNA complex	C	A protein-DNA complex that consists of HU heterodimers (an alpha and a beta chain) assembled into octamers along DNA. HU binds to double-stranded DNA in a structure- and sequence-specific manner and bends the DNA into a nucleosome-like structure.
1990179	protein localization to actomyosin contractile ring	P	A process in which a protein is transported to, or maintained at, the actomyosin contractile ring.
1990180	mitochondrial tRNA 3'-end processing	P	The process in which the 3' end of a pre-tRNA molecule is converted to that of a mature tRNA in the mitochondrion.
1990181	acetyl-CoA biosynthetic process from pantothenate	P	The chemical reactions and pathways resulting in the formation of acetyl-CoA from pantothenate via phosphopantothenate and CoA.
1990182	exosomal secretion	P	The process whereby a membrane-bounded vesicle is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane.
1990183	lymphatic vascular process in circulatory system	P	A circulatory process that occurs at the level of the lymphatic vasculature.
1990184	amino acid transport complex	C	A heteromeric protein complex consisting of a multi-transmembrane spanning subunit (the light chain) and a type II glycoprotein subunit (the heavy chain) that functions to transport amino acids across a plasma membrane.
1990185	regulation of lymphatic vascular permeability	P	Any process that modulates the extent to which lymphatic vessels can be pervaded by fluid.
1990186	regulation of lymphatic vessel size	P	Any process that modulates the size of lymphatic vessels.
1990188	euchromatin binding	F	Interacting selectively and non-covalently with euchromatin, a dispersed and relatively uncompacted form of chromatin.
1990189	peptide-serine-N-acetyltransferase activity	F	Catalysis of the reaction: acetyl-CoA + N-terminal L-serine in peptide = CoA + N-acetyl-L-serine-peptide.
1990190	peptide-glutamate-N-acetyltransferase activity	F	Catalysis of the reaction: acetyl-CoA + N-terminal L-glutamate in peptide = CoA + N-acetyl-L-glutamate-peptide.
1990191	cobalamin transport complex	C	Protein complex facilitating ATP-dependent cobalamin (vitamin B12) transport through inner cell membrane (periplasm to cytoplasm) in Gram-negative bacteria. In E. coli the system is composed of a periplasmic cobalamin-binding protein (BtuF), an integral membrane homodimer, BtuC, and a cytoplasmic ATP-binding homodimer BtuD.
1990192	collecting lymphatic vessel constriction	P	A decrease in the diameter of collecting lymphatic vessels.
1990193	BtuCD complex	C	Protein complex involved in cobalamin (vitamin B12) transport through the plasma membrane. In E. coli, the complex is a tetramer and consists of the cytoplasmic ATPase BtuD homodimer together with the transmembrane BtuC homodimer.
1990194	cytoplasmic U snRNP body assembly	P	The aggregation, arrangement and bonding together of proteins and RNA molecules to form a cytoplasmic U snRNP body.
1990195	macrolide transmembrane transporter complex	C	A bacterial transmembrane transporter complex that spans the entire cell membrane system and possesses ATP-dependent xenobiotic transport activity pumping drugs (typically antibiotics) and other toxins directly from the cytosol out of the bacterial cell. Typically, it is trimeric consisting of a inner membrane ATPase (IMP), a periplasmic membrane fusion protein (MFP) and an outer membrane factor (OMF). In E. coli, macrolide transporter complexes may consists of MacB (IMP), MacA (MFP) and TolC (OMF) or AcrB (IMP), AcrA (MFP) and TolC (OMF). Trimeric TolC is a common OMF found in many macrolide transporter complexes.
1990196	MacAB-TolC complex	C	The MacAB-TolC complex is a macrolide transporter complex found in E.coli and related gram-negative bacteria. Its transport activity is specific to macrolide compounds containing 14- and 15-membered lactones. It consists of the dimeric inner membrane ATPase MacB, the hexameric, periplasmic membrane fusion protein MacA and the trimeric outer membrane factor TolC.
1990197	ATP-dependent methionine-importing complex	C	An ATP-binding cassette (ABC) transporter complex that is capable of methionine-importing activity. An example is the bacterial MetNIQ methionine transporter, that consists of the dimeric ATPase subunit MetN located at the cytoplasmic side of the plasma membrane and the dimeric transmembrane subunit MetI. MetQ is regarded as the periplasmic methionine-binding chaperon subunit, and is capable of transporting methionine from the periplasm into the cytoplasm in an ATP-dependent manner.
1990198	ModE complex	C	A dimeric protein complex containing two ModE subunits. Binds directly to DNA to regulate transcription, and is involved in (positively and negatively) regulating various aspects of molybdenum metabolism.
1990199	MsbA transporter complex	C	An ATP-binding cassette (ABC) transporter complex made up of a dimer of MsbA. Facilitates the export across the plasma membrane of, amongst others, lipid A and lipopolysaccharide. In contrast to most ABC transporter complexes, each chain of the homodimer contains both the transmembrane domain (TMD) and the cytoplasmic ATP-binding domain (NBD).
1990200	SsuD-SsuE complex	C	A protein complex containing an alkanesulfonate monooxygenase subunit (SsuD tetramer in E.coli) and a flavin oxidoreductase subunit (SsuE dimer in E.coli). Involved in the utilization of alkanesulfonates as sulfur sources under conditions of sulfate or cysteine starvation.
1990201	alkanesulfonate monooxygenase complex	C	A protein complex capable of alkanesulfonate monooxygenase activity. Involved in the utilization of alkanesulfonates as sulfur sources under conditions of sulfate or cysteine starvation, catalyzing the conversion of alkanesulfonates into aldehydes and sulfite. In E.coli the complex consists of a SsuD tetramer.
1990202	FMN reductase complex	C	A protein complex capable of FMN reductase activity. Reduces FMN to FMNH2 in a NAD(P)H-dependent manner. In E.coli, consists of a SsuE dimer.
1990203	MdtBC Complex	C	A protein complex containing two transmembrane subunits; a MdtB dimer and one unit of MdtC. Capable of exporting substrates across the cell membrane. Involved in conferring antibiotic resistance of Gram-negative bacteria by transporting drugs across the membrane.
1990204	oxidoreductase complex	C	Any protein complex that possesses oxidoreductase activity.
1990205	taurine dioxygenase complex	C	A protein complex capable of catalyzing the conversion of taurine and alpha-ketoglutarate to sulfite, aminoacetaldehyde and succinate under sulfur or cysteine starvation conditions. Its expression is repressed by the presence of sulfate or cysteine. In E. coli it is a homodimer or homotetramer of the protein TauD.
1990206	jasmonyl-Ile conjugate hydrolase activity	F	Catalysis of the reaction: jasmonyl-Ile + H2O = jasmonic acid + L-isoleucine.
1990207	EmrE multidrug transporter complex	C	A transmembrane protein complex capable of transporting positively charged hydrophobic drugs across the plasma membrane thereby involved in conferring resistance to a wide range of toxic compounds (e.g. methyl viologen, ethidium bromide and acriflavine). It is commonly found in bacteria. In E. coli it forms a homodimer.
1990208	positive regulation by symbiont of RNA levels in host	P	Any process in which an organism activates, maintains or increases the frequency, rate or extent of the RNA levels in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
1990209	negative regulation by symbiont of RNA levels in host	P	Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of the RNA levels in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
1990210	positive regulation by symbiont of indole acetic acid levels in host	P	Any process in which an organism activates, maintains or increases the frequency, rate or extent of the indole acetic acid levels in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
1990211	positive regulation by symbiont of jasmonic acid levels in host	P	Any process in which an organism activates, maintains or increases the frequency, rate or extent of the jasmonic acid levels in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
1990212	positive regulation by symbiont of ethylene levels in host	P	Any process in which an organism activates, maintains or increases the frequency, rate or extent of the ethylene levels in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
1990213	negative regulation by symbiont of salicylic acid levels in host	P	Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of salicylic acid levels in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
1990214	negative regulation by symbiont of host protein levels	P	Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of protein levels in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
1990215	negative regulation by symbiont of host intracellular transport	P	Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of intracellular transport in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
1990216	positive regulation by symbiont of host transcription	P	Any process in which an organism activates, maintains or increases the frequency, rate or extent of transcription in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
1990217	negative regulation by symbiont of host phytoalexin production	P	Any process in which an organism stops, prevents, or reduces the frequency, rate or extent of phytoalexin production in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
1990218	positive regulation by symbiont of abscisic acid levels in host	P	Any process in which an organism activates, maintains or increases the frequency, rate or extent of the abscisic acid levels in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
1990219	positive regulation by symbiont of host protein levels	P	Any process in which an organism activates, maintains or increases the frequency, rate or extent of protein levels in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
1990220	GroEL-GroES complex	C	Bacterial chaperonin complex consisting of a heptameric 10kDa chaperonin subunit GroES and a tetradecameric (2x7) 60kDa chaperonin subunit GroEL. The 60kDa subunit possesses ATPase activity while the holo-enzyme is responsible for the correct folding of proteins.
1990221	L-cysteine desulfurase complex	C	A protein complex capable of cysteine desulfurase activity decomposing L-cysteine to L-alanine and sulfur. It belongs to a ubiquitous family of pyridoxal 5-phosphate (PLP)-dependent enzymes. In E. coli it consists of a SufS dimer.
1990222	ProVWX complex	C	The ProVWX complex belongs to the family of ATP-binding cassette (ABC) transporter proteins complexes. It consists of a cytoplasmic ATPase subunit ProV, a transmembrane subunit ProW and a periplasmic binding protein ProX. It is capable of translocating a wide variety of solute (e.g. glycine betaine) across the plasma membrane and is activated under osmotic stress conditions.
1990223	positive regulation by symbiont of cytokinin levels in host	P	Any process in which an organism activates, maintains or increases the frequency, rate or extent of the cytokinin levels in the host organism. The host is defined as the larger of the organisms involved in a symbiotic interaction.
1990224	NMN phosphatase activity	F	Catalysis of the reaction: beta-nicotinamide D-ribonucleotide (NMN-) + H2O = beta-nicotinamide D-riboside (nicotinamide ribose, NmR) + phosphate.
1990225	rhoptry neck	C	Narrow, electron-dense part of the rhoptry that extends through the conoid at the apical tip of an apicomplexan parasite. The rhoptry neck serves as a duct through which the contents of the rhoptry are secreted after attachment to the host has been completed and at the commencement of invasion.
1990226	histone methyltransferase binding	F	Interacting selectively and non-covalently with a histone methyltransferase enzyme.
1990227	paranodal junction maintenance	P	The maintenance of a paranodal junction, a highly specialized cell-cell junction found in vertebrates, which forms between a neuron and a glial cell, and has structural similarity to Drosophila septate junctions. A paranodal junction flanks the node of Ranvier in myelinated nerve, electrically isolates the myelinated from unmyelinated nerve segments, and physically separates the voltage-gated sodium channels at the node from the cluster of potassium channels underneath the myelin sheath.
1990228	sulfurtransferase complex	C	A protein complex capable of catalyzing the transfer of sulfur atoms from one compound (donor) to another (acceptor).
1990229	iron-sulfur cluster assembly complex	C	A protein complex capable of assembling an iron-sulfur (Fe-S) cluster.
1990230	iron-sulfur cluster transfer complex	C	A protein complex capable of catalyzing the transfer of an iron-sulfur (Fe-S) cluster from one compound (donor) to another (acceptor).
1990231	STING complex	C	A protein dimer containing two STING monomers. It binds cyclic purine di-nucleotides. Activation of the sting complex by 2',5'-3'-5'-cyclic GMP-AMP activates nuclear transcription factor kB (NF-kB) and interferon regulatory factor 3 (IRF3) which then induce transcription of the genes encoding type I IFN and cytokines active in the innate immune response.
1990232	phosphomannomutase complex	C	A protein complex capable of phosphomannomutase activity.
1990233	intramolecular phosphotransferase complex	C	A protein complex capable of catalyzing the transfer of a phosphate group from one position to another within a single molecule.
1990234	transferase complex	C	A protein complex capable of catalyzing the transfer of a group, e.g. a methyl group, glycosyl group, acyl group, phosphorus-containing, or other groups, from one compound (generally regarded as the donor) to another compound (generally regarded as the acceptor).
1990235	diamine N-acetyltransferase complex	C	A protein complex which is capable of diamine N-acetyltransferase activity.
1990236	proteasome core complex import into nucleus	P	The directed movement of the proteasome core complex (AKA core particle (CP)) from the cytoplasm into the nucleus.
1990237	sequestration of proteasome core complex in proteasome storage granule	P	Any process where the proteasome core particle (CP) is sequestered in the protein storage granule in the cytoplasm.
1990238	double-stranded DNA endodeoxyribonuclease activity	F	Catalysis of the hydrolysis of ester linkages within a double-stranded deoxyribonucleic acid molecule by creating internal breaks.
1990239	steroid hormone binding	F	Interacting selectively and non-covalently with a steroid hormone.
1990240	methionine-importing activity	F	Catalysis of the transfer of methionine into a cell or organelle, across a membrane.
1990243	atf1-pcr1 complex	C	A heterodimeric transcription factor complex composed of the bZIP proteins atf1 and pcr1. The heterodimer binds m26 sites (homologous to CRE).
1990244	histone kinase activity (H2A-T120 specific)	F	Catalysis of the transfer of a phosphate group to the threonine-120 residue of histone H2A.
1990245	histone H2A-T120 phosphorylation	P	The modification of histone H2A by the addition of a phosphate group to a threonine residue at position 120 of the histone.
1990246	uniplex complex	C	A calcium channel complex in the mitochondrial inner membrane capable of highly-selective calcium channel activity. Its components include the EF-hand-containing proteins mitochondrial calcium uptake 1 (MICU1) and MICU2, the pore-forming subunit mitochondrial calcium uniporter (MCU) and its paralog MCUb, and the MCU regulator EMRE.
1990247	N6-methyladenosine-containing RNA binding	F	Interacting selectively and non-covalently with an RNA molecule modified by N6-methyladenosine (m6A), a modification present at internal sites of mRNAs and some non-coding RNAs.
1990248	regulation of transcription from RNA polymerase II promoter in response to DNA damage	P	Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of DNA damage.
1990249	nucleotide-excision repair, DNA damage recognition complex	C	A protein complex that is capable of identifying lesions in DNA, such as pyrimidine-dimers, intrastrand cross-links, and bulky adducts. The wide range of substrate specificity suggests that the repair complex recognizes distortions in the DNA helix. It subsequently recruits a nucleotide-excision repair, preincision complex.
1990250	transcription-coupled nucleotide-excision repair, DNA damage recognition complex	C	A protein complex that is capable of identifying lesions in DNA on the actively transcribed strand of the DNA duplex as well as a small subset of lesions not recognized by the general nucleotide-excision repair pathway. The wide range of substrate specificity suggests that the repair complex recognizes distortions in the DNA helix. It subsequently recruits a nucleotide-excision repair, preincision complex.
1990251	Mmi1 nuclear focus complex	C	A protein complex that forms during vegetative growth and is involved in the selective degradation of meiosis-specific transcripts. Contains at least Mmi1, or an ortholog of it.
1990252	Syp1 complex	C	A protein complex that contributes to the endocytic process and bud growth in yeast. It is involved in the precise timing of actin assembly during endocytosis.
1990253	cellular response to leucine starvation	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of leucine.
1990254	keratin filament binding	F	Interacting selectively and non-covalently with a keratin filament, an intermediate filament composed of acidic and basic keratins (types I and II), typically expressed in epithelial cells.
1990255	subsynaptic reticulum organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a subsynaptic reticulum. A subsynaptic reticulum is an elaborate tubulolamellar membrane system that underlies the postsynaptic cell membrane.
1990256	signal clustering	P	Grouping of multiple copies of a signal at a cellular location. May promote receptor clustering and alter the signal transduction response.
1990257	piccolo-bassoon transport vesicle	C	A cytoplasmic dense-core vesicle that transports a range of proteins including piccolo, bassoon, N-cadherin and syntaxin. The transported proteins may be associated with the external side of the vesicle, rather than being contained within the vesicle, therefore forming an aggregate of vesicle and proteins. Piccolo-bassoon transport vesicles (or PTVs) range in size from approximately 80 nm in diameter for dense core vesicles to 130 nm by 220 nm in area for aggregates. They are packaged via the trans-Golgi network before being transported through the axon.
1990258	histone glutamine methylation	P	The modification of a histone by addition of a methyl group to an glutamine residue.
1990259	histone-glutamine methyltransferase activity	F	Catalysis of the reaction: S-adenosyl-L-methionine + (histone)-glutamine = S-adenosyl-L-homocysteine + (histone)-N5-methyl-glutamine.
1990260	negative regulation of transcription from RNA polymerase II promoter by transcription factor localization involved in response to DNA damage checkpoint signaling	P	Any process that stops, prevents, or reduces the frequency, rate or extent of transcription from an RNA polymerase II promoter using a mechanism that involves the localization of a transcription factor and initiated in response to the DNA damage checkpoint signaling.
1990261	pre-mRNA catabolic process	P	The chemical reactions and pathways resulting in the breakdown of the unspliced pre-mRNA (pre-messenger RNA).
1990262	anti-Mullerian hormone signaling pathway	P	A series of molecular signals initiated by the binding of anti-Mullerian hormone to its receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.
1990263	MAPK cascade in response to starvation	P	A MAPK cascade that occurs as a result of deprivation of nourishment.
1990264	peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity	P	Any peptidyl-tyrosine dephosphorylation that is involved in inactivation of protein kinase activity.
1990265	platelet-derived growth factor complex	C	A protein complex consisting of two chains of platelet-derived growth factor (PDGF) subunits. PDGF dimers bind to PDGF receptors in the plasma membrane and induce receptor dimerisation and activation. PDGFs are involved in a wide variety of signalling processes. PDGFs are found in all vertebrates where at least 2 different chains (A and B) exist. In human (and other mammals), four types of PDGF chains (A, B, C, and D) are known which form five different dimers (AA, AB, BB, CC and DD).
1990266	neutrophil migration	P	The movement of an neutrophil within or between different tissues and organs of the body.
1990267	response to transition metal nanoparticle	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a transition metal nanoparticle.
1990268	response to gold nanoparticle	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gold nanoparticle stimulus.
1990269	RNA polymerase II C-terminal domain phosphoserine binding	F	Interacting selectively and non-covalently with phosphorylated serine residues in the C-terminal domain of RNA polymerase II.
1990270	platelet-derived growth factor receptor-ligand complex	C	A tetrameric protein complex consisting of two platelet-derived growth factor (PDGF) receptor subunits and two PDGF ligand subunits. Binding of the PDGF ligand dimer to the PDGF receptor in the plasma membrane induces receptor dimerisation and activation. PDGFs are involved in a wide variety of signalling processes and are found in all vertebrates. At least two different receptor chains (A and B) and four types of ligand chains (A, B, C, and D) are known forming a wide variety of combinations of receptor-ligand complexes.
1990272	anti-Mullerian hormone receptor activity	F	Combining with anti-Mullerian hormone to initiate a change in cell activity.
1990273	snRNA 5'-end processing	P	Any process involved in forming the mature 5' end of an snRNA molecule.
1990274	mitotic actomyosin contractile ring disassembly	P	Any disaggregation of an actomyosin contractile ring into its constituent components that is involved in a mitotic cell cycle.
1990275	preribosome binding	F	Interacting selectively and non-covalently with any part of a preribosome.
1990276	RNA 5'-methyltransferase activity	F	Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to the 5'-gamma-phosphate in an RNA molecule.
1990277	parasexual conjugation with cellular fusion	P	A conjugation process that results in the union of cellular and genetic information from compatible mating types, without the formation of zygotes. An example of this process is found in Candida albicans.
1990280	RNA localization to chromatin	P	A process in which RNA is transported to and maintained in a part of a chromosome that is organized into chromatin.
1990281	efflux pump complex	C	A protein complex that is capable of efflux transmembrane transporter activity.
1990294	peptidyl-threonine trans-autophosphorylation	P	The phosphorylation of a peptidyl-threonine to form peptidyl-O-phospho-L-threonine on an identical protein. For example, phosphorylation by the other kinase within a homodimer.
1990295	post-anaphase microtubule array	C	A cytoskeletal part that consists of an array of microtubules and associated molecules that forms at the end of anaphase, and in which microtubules are nucleated from an equatorial microtubule organizing center.
1990296	scaffoldin complex	C	A protein complex that contains one or more scaffoldin proteins and several cellulosomal enzymes.
1990297	renal amino acid absorption	P	A renal system process in which amino acids are taken up from the collecting ducts, glomerulus and proximal and distal loops of the nephron. In non-mammalian species, absorption may occur in related structures.
1990298	bub1-bub3 complex	C	Protein complex that associates with the kinetochores.
1990299	Bub1-Bub3 complex localization to kinetochore	P	A cellular protein complex localization that acts on a Bub1-Bub3 complex; as a result, the complex is transported to, or maintained in, a specific location at the kinetochore.
1990300	cellulosome binding	F	Interacting selectively and non-covalently with the cellulosome, an extracellular multi-enzyme complex containing several enzymes aligned on a non-catalytic scaffolding that functions to hydrolyze plant cell wall polysaccharides.
1990301	scaffoldin complex binding	F	A protein complex that contains one or more scaffoldin proteins and several cellulosomal enzymes ant that interacts selectively and non-covalently with the scaffoldin complex.
1990302	Bre1-Rad6 ubiquitin ligase complex	C	A ubiquitin ligase complex consisting of Bre1 and Rad6 that mediates monoubiquitination of histone H2B to form H2BK123ub1. H2BK123ub1 gives a specific tag for epigenetic transcriptional activation, elongation by RNA polymerase II, telomeric silencing, and is also a prerequisite for H3K4me and H3K79me formation. It thereby plays a central role in histone code and gene regulation. It also modulates the formation of double-strand breaks during meiosis.
1990303	UBR1-RAD6 ubiquitin ligase complex	C	A ubiquitin ligase complex consisting of UBR1 and RAD6 components. It polyubiquitinates proteins containing non-acetylated N-terminal residues causing their subsequent degradation by the proteasome as part of the Ac/N-End Rule pathway. It recognizes non-acetylated N-terminal methionine if it is followed by a hydrophobic residue. Additionally, it acts in an N-end rule independent manner as a component of a novel quality control pathway for proteins synthesized on cytosolic ribosomes.
1990304	MUB1-RAD6-UBR2 ubiquitin ligase complex	C	A ubiquitin ligase complex consisting of MUB1, RAD6 and UBR2 components. It ubiquitinates, and targets for destruction, the RPN4 transcription factor, which upregulates the proteasome genes. The binding of MUB1 may position the RPN4 ubiquitylation site proximal to the Ubiquitin-RAD6 thioester and allow the transfer of Ubiquitin from RAD6 to RPN4. One of its components, MUB1, is a short-lived protein ubiquitinated by the UBR2-RAD6 ubiquitin conjugating enzyme.
1990305	RAD6-UBR2 ubiquitin ligase complex	C	A ubiquitin ligase complex consisting of RAD6 and UBR2 components. It may act in a quality control pathway for proteins synthesized on cytosolic ribosomes. The UBR2 component lacks sequence motifs required for N-end rule degradation.
1990306	RSP5-BUL ubiquitin ligase complex	C	A ubiquitin ligase complex consisting of RSP5 and BUL components. It polyubiquinates plasma membrane transporters and permeases, required for their endocytosis and subsequent degradation in the vacuole. BUL1 or BUL2, respectively, bind to the target protein, enabling ubiquitylation by Rsp5. Phosphorylation of BUL proteins results in binding to 14-3-3 proteins, protecting the permeases from down-regulation.
1990308	Type-I dockerin domain binding	F	Interacting selectively and non-covalently with a type-I dockerin domain of a protein. Type-I dockerin domain is the binding partner of type-1 cohesin domain.
1990309	Type-II dockerin domain binding	F	Interacting selectively and non-covalently with a type-II dockerin domain of a protein. Type-II dockerin domain is the binding partner of type-II cohesin domain.
1990310	Type-III dockerin domain binding	F	Interacting selectively and non-covalently with a type-III dockerin domain of a protein. Type-III dockerin domain is the binding partner of type-III cohesin domain.
1990311	Type-I cohesin domain binding	F	Interacting selectively and non-covalently with a type-I cohesin domain of a protein. Type-I cohesin domain is the binding partner of type-I dockerin domain.
1990312	Type-II cohesin domain binding	F	Interacting selectively and non-covalently with a type-II cohesin domain of a protein. Type-II cohesin domain is the binding partner of type-II dockerin domain.
1990313	Type-III cohesin domain binding	F	Interacting selectively and non-covalently with a type-III cohesin domain of a protein. Type-III cohesin domain is the binding partner of type-III dockerin domain.
1990314	cellular response to insulin-like growth factor stimulus	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin-like growth factor stimulus.
1990315	Mcs4 RR-MAPKKK complex	C	A protein complex that consists of a phospho relay component and a MAPK cascade component. The complex is involved in signaling oxidative stress and osmostress.
1990316	ATG1/ULK1 kinase complex	C	A protein complex consisting of ATG1/ULK1 and ATG13 along with other proteins that regulate its function (e.g. ATG17 in yeast or RB1CC1(FIP200) in mammals). This complex has serine/threonine protein kinase activity and is involved in autophagosome formation.
1990317	Gin4 complex	C	A protein complex involved in septin ring formation during mitosis. In Saccharomyces cerevisiae it consists of BNI5, CDC3, CDC10, CDC11, CDC12, GIN4, NAP1 and SHS1. At least 2 GIN4 molecules are involved.
1990318	collagen type XIX trimer	C	A collagen homotrimer of alpha1(XIX) chains; type XIX collagen triple helices localize to basement membrane zones in differentiating muscle cells.
1990319	collagen type XX trimer	C	A collagen homotrimer of alpha1(XX) chains.
1990320	collagen type XXI trimer	C	A collagen homotrimer of alpha1(XXI) chains; type XXI collagen triple helices found in the extracellular matrix component of blood vessel walls and in the cytoplasm of cultured human aortic smooth muscle.
1990321	collagen type XXII trimer	C	A collagen homotrimer of alpha1(XXII) chains; type XXII collagen triple helices acts as a cell adhesion ligand for skin epithelial cells and fibroblasts.
1990322	collagen type XXIII trimer	C	A collagen homotrimer of alpha1(XXIII) chains; type XXIII collagen triple helices span the plasma membrane.
1990323	collagen type XXIV trimer	C	A collagen homotrimer of alpha1(XXIV) chains; type XXIV collagen triple helices may participate in regulating type I collagen fibrillogenesis at specific anatomical locations during fetal development.
1990324	collagen type XXVI trimer	C	A collagen homotrimer of alpha1(XXVI) chains.
1990325	collagen type XXVII trimer	C	A collagen homotrimer of alpha1(XXVII) chains. These trimers form thin, non-striated fibrils. Type XXVII collagen triple helices play a role during the calcification of cartilage and the transition of cartilage to bone.
1990326	collagen type XXVIII trimer	C	A collagen homotrimer of alpha1(XXVIII) chains.
1990327	collagen type XXV trimer	C	A collagen homotrimer of alpha1(XXV) chains; type XXV collagen triple helices span the plasma membrane.
1990328	RNA polymerase II, RPB4-RPB7 subcomplex	C	A protein complexes that mediates transcription and the two major cytoplasmic mRNA decay pathways and is required for efficient translation initiation in association with RNA polymerase II (Pol II).
1990329	IscS-TusA complex	C	A heterotetrameric protein complex involved in the sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm5s2U) at tRNA wobble positions. In E. coli it consists of a central IscS dimer with the two TusA protomers bound to one of the IscS units each via persulfide (-SSH) groups.
1990330	IscS-IscU complex	C	A heterotetrameric protein complex involved in the sulfur transfer during iron-sulfur cluster assembly and in the modification of tRNA wobble positions. In E. coli it consisting of a central IscS dimer with the IscU protomers attached to one of the IscS units each via a disulfide (-SSH) group.
1990331	Hpa2 acetyltransferase complex	C	A tetrameric protein complex capable of acetyltransferase activity. It can catalyze the transfer of an acetyl group from acetyl-CoA to an acceptor residue on histone H-3, histone H-4, or on polyamines. The complex is also capable of acetylating certain small basic proteins. The two Hpa2 dimers that make up the tetramer are held together by interactions between the bound acetyl-CoA molecules.
1990332	Ire1 complex	C	A type-I transmembrane protein complex located in the endoplasmic reticulum (ER) consisting of an IRE1-IRE1 dimer, which forms in response to the accumulation of unfolded protein in the ER. The dimeric complex has endoribonuclease (RNase) activity and evokes the unfolded protein response (UPR) by cleaving an intron of a mRNA coding for the transcription factor HAC1 in yeast or XBP1 in mammals; the complex cleaves a single phosphodiester bond in each of two RNA hairpins (with non-specific base paired stems and loops of consensus sequence CNCNNGN, where N is any base) to remove an intervening intron from the target transcript.
1990333	mitotic checkpoint complex, CDC20-MAD2 subcomplex	C	A protein complex involved in the spindle checkpoint, preventing the activation of the anaphase-promoting complex until all chromosomes are correctly attached in a bipolar fashion to the mitotic spindle. In budding yeast this complex consists of Mad2p and Cdc20p, and in mammalian cells it consists of MAD2 and CDC20.
1990334	Bfa1-Bub2 complex	C	A protein complex that acts as a two-component GTPase-activating protein for Tem1 GTPase, thus regulating a signal transduction cascade, called the mitotic exit network (MEN), which is required for mitotic exit and cytokinesis. Bub2/Bfa1 keeps Tem1 inactive until the spindle is properly oriented, thus inhibiting MEN activation.
1990335	process resulting in tolerance to alcohol	P	A response to alcohol that results in a state of tolerance to alcohol.
1990336	process resulting in tolerance to butan-1-ol	P	A response to butan-1-ol that results in a state of tolerance to butan-1-ol.
1990337	process resulting in tolerance to isobutanol	P	A response to isobutanol that results in a state of tolerance to isobutanol.
1990338	laminin-14 complex	C	A laminin complex composed of alpha4, beta2 and gamma3 polypeptide chains.
1990339	laminin-522 complex	C	A laminin complex composed of alpha5, beta2 and gamma2 polypeptide chains.
1990340	laminin-15 complex	C	A laminin complex composed of alpha5, beta2 and gamma3 polypeptide chains.
1990341	thrombospondin complex	C	A homotrimeric or homopentameric glycoprotein that functions at the interface of the cell membrane and the extracellular matrix through its interactions with proteins and proteoglycans, such as collagens, integrins and fibronectin, to regulate matrix structure and cellular behaviour.
1990342	heterochromatin island	C	A region of heterochromatin that is formed dynamically in response to environmental signals by a process that does not require RNAi, and is enriched in histone H3 methylated on lysine 9 (H3K9me).
1990343	heterochromatin domain	C	A region of heterochromatin that is formed dynamically under specific growth conditions by a process that requires RNAi, and is enriched in histone H3 methylated on lysine 9 (H3K9me).
1990344	secondary cell septum biogenesis	P	A cellular process that results in the biosynthesis of constituent macromolecules, assembly, and arrangement of constituent parts of a secondary cell septum following nuclear division.
1990345	MTREC complex	C	A protein complex that consists of a heterodimer formed by Red1 and Mtl1 or homologs thereof, and that promotes degradation of mRNAs and noncoding RNAs and associates with different proteins to assemble heterochromatin via distinct mechanisms.
1990346	BID-BCL-xl complex	C	A heterodimeric protein complex consisting of BID and BCL-xl, members of the Bcl-2 family of anti- and proapoptotic regulators.
1990349	gap junction-mediated intercellular transport	P	The movement of substances between cells via gap junctions. A gap junction is a fine cytoplasmic channel, found in animal cells, that connects the cytoplasm of one cell to that of an adjacent cell, allowing ions and other molecules to pass freely between the two cells.
1990350	glucose transporter complex	C	A protein complex facilitating glucose transport into, out of or within a cell, or between cells.
1990351	transporter complex	C	A protein complex facilitating transport of molecules (proteins, small molecules, nucleic acids) into, out of or within a cell, or between cells.
1990352	BRE1 E3 ubiquitin ligase complex	C	A homodimeric protein complex composed of the E3 ubiquitin-protein ligase BRE1. Plays a role in regulating association of RNA polymerase II with active genes.
1990353	Fused-Smurf ubiquitin ligase complex	C	A ubiquitin ligase complex. In D. melanogaster, it regulates ubiquitination and proteolysis of the BMP receptor Thickveins in cystoblasts, potentially by controlling Tkv ubiquitination and degradation.
1990354	activated SUMO-E1 ligase complex	C	A protein complex consisting of a SUMO protein bound to a SUMO activating enzyme complex. Activation by the E1 complex and linkage to the E2 enzyme UBE2I is required for the formation of covalent bonds between SUMO and its ultimate target proteins.
1990355	L-methionine salvage from methionine sulphoxide	P	The generation of L-methionine from methionine sulphoxide.
1990356	sumoylated E2 ligase complex	C	A protein complex consisting of a SUMO (small ubiquitin-related modifier) protein bound to a SUMO-conjugating E2 ligase. Sumoylation of the E2 ligase is an intermediate step required for the formation of covalent bonds between a SUMO protein and its ultimate protein target. SUMO is transferred to the E2 ligase by a SUMO-activating E1 enzyme. Sumoylation of the target protein is either facilitated directly by the sumoylated E2 ligase or aided by an optional E3 ligase.
1990357	terminal web	C	An actin-rich cytoskeletal network located beneath the microvilli of the apical plasma membrane of polarized epithelial cells. In addition to actin filaments, the terminal web may contain actin-binding proteins, myosin motor proteins, and intermediate filaments. The terminal web can function as a contractile structure that influences the spatial distribution of microvilli as well as the development and morphogenesis of tissues containing polarized epithelial cells.
1990358	xylanosome	C	A multifunctional supermolecular complex, containing several proteins with hemicellulase activity. Functions to hydrolyze hemicellulose.
1990359	stress response to zinc ion	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis caused by a zinc ion stimulus.
1990360	PKM2 protein kinase complex	C	A protein complex capable of phosphorylating a large number of protein targets. Contributes to cell proliferation under glycose starvation conditions. In human, the complex is present as a dimer.
1990361	PKM2 pyruvate kinase complex	C	A protein complex capable of pyruvate kinase activity. PKM2 only exists as homotetramer when bound to beta-d-fructofuranose 1,6-bisphosphate (CHEBI:28013).
1990362	butanol dehydrogenase activity	F	Catalysis of the reaction: butanal + NADH + H+ => n-butanol + NAD+.
1990367	process resulting in tolerance to organic substance	P	A response that results in a state of tolerance to an organic substance.
1990369	process resulting in tolerance to ketone	P	A response that results in a state of tolerance to ketone.
1990370	process resulting in tolerance to aldehyde	P	A response that results in a state of tolerance to aldehyde.
1990371	process resulting in tolerance to phenol	P	A response that results in a state of tolerance to phenol.
1990372	process resulting in tolerance to organic acid	P	A response that results in a state of tolerance to organic acid.
1990373	process resulting in tolerance to alkane	P	A response that results in a state of tolerance to alkane.
1990374	Kir2 inward rectifier potassium channel complex	C	A inward rectifier potassium channel complex. Homo- or heterotetramer composed of subunits of the eukaryotic Kir2 protein family. Plays a key role in maintaining the correct resting potential in eukaryotic cells.
1990375	baculum development	P	The reproductive developmental process whose specific outcome is the progression of the baculum over time, from its formation to the mature structure.
1990377	organomineral extracellular matrix	C	An extracellular matrix consisting of a densely packed organomineral assembly in which the mineral phase represents the majority of the material by weight.
1990378	upstream stimulatory factor complex	C	A protein complex capable of sequence-specific DNA binding RNA polymerase II transcription factor activity through binding to a symmetrical DNA sequence (E-boxes) (5'-CACGTG-3'). Found in a variety of viral and cellular promoters.
1990379	lipid transport across blood brain barrier	P	The directed movement of lipid molecules passing through the blood-brain barrier.
1990380	Lys48-specific deubiquitinase activity	F	Hydrolysis of Lys48-linked ubiquitin unit(s) from a ubiquitinated protein.
1990381	ubiquitin-specific protease binding	F	Interacting selectively and non-covalently with a ubiquitin-specific protease.
1990383	cellular response to biotin starvation	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of biotin.
1990384	hyaloid vascular plexus regression	P	The developmental process in which the hyaloid vascular plexus is destroyed as a part of its normal progression.
1990385	meiotic spindle midzone	C	The area in the center of the meiotic spindle where the spindle microtubules from opposite poles overlap.
1990386	mitotic cleavage furrow ingression	P	Advancement of the mitotic cleavage furrow from the outside of the cell inward towards the center of the cell. The cleavage furrow acts as a 'purse string' which draws tight to separate daughter cells during mitotic cytokinesis and partition the cytoplasm between the two daughter cells. The furrow ingresses until a cytoplasmic bridge is formed.
1990387	isogloboside biosynthetic process	P	The chemical reactions and pathways resulting in the formation of a lactosyl-ceramide derivative in which a galactose is linked to the galactose via an alpha 1,3 linkage (vs alpha 1,4 for globosides).
1990388	xylem-to-phloem iron transport	P	The directed movement of iron ions into the phloem from the xylem.
1990389	CUE1-UBC7 ubiquitin-conjugating enzyme complex	C	A protein complex capable of ubiquitin-conjugating enzyme activity during ER-associated protein degradation (ERAD). In S. cerevisiae, UBC7 is the ubiquitin-conjugating enzyme (E2) and requires binding to the ER surface by CUE1.
1990390	protein K33-linked ubiquitination	P	A protein ubiquitination process in which a polymer of ubiquitin, formed by linkages between lysine residues at position 33 of the ubiquitin monomers, is added to a protein.
1990391	DNA repair complex	C	A protein complex involved in DNA repair processes including direct reversal, base excision repair, nucleotide excision repair, photoreactivation, bypass, double-strand break repair pathway, and mismatch repair pathway.
1990392	EFF-1 complex	C	A trimeric cell-cell fusion complex that serves as a scaffold for zippering up the extracellular domains, bringing the transmembrane segments into close proximity such that they can continue zippering within the two membranes into one. Two prefusion monomers cluster at the surface of adjacent cells. Parallel EFF-1 interactions occur across cells and a third monomer, which can come from either cell, adds on to make an intermediate, extended trimer.
1990393	3M complex	C	A protein complex, at least composed of CUL7, CCDC8 and OBSL1, that is required for maintaining microtubule and genome integrity.
1990394	cellular response to cell wall damage	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of cell wall damage. The process begins with detection of the damage and ends with a change in state or activity of the cell.
1990395	meiotic spindle pole body organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the meiotic spindle pole body.
1990396	single-strand break repair via homologous recombination	P	The error-free repair of a single-strand break in DNA in which the broken DNA molecule is repaired using homologous sequences. A strand in the broken DNA searches for a homologous region in an intact chromosome to serve as the template for DNA synthesis. The restoration of two intact DNA molecules results in the exchange, reciprocal or nonreciprocal, of genetic material between the intact DNA molecule and the broken DNA molecule.
1990397	queuosine salvage	P	Any process which produces queuosine from derivatives of it, without de novo synthesis.
1990398	Cus cation efflux complex	C	Transmembrane complex that mediates resistance to copper and silver by cation efflux directly from the cell using the proton-motive force. Spans the inner membrane, periplasm, and outer membrane. Primarily activated under anaerobic conditions by CusR and CusS but also expressed under extreme copper stress, in aerobic growth.
1990399	epithelium regeneration	P	The regrowth of lost or destroyed epithelium.
1990400	mitochondrial ribosomal large subunit rRNA binding	F	Interacting selectively and non-covalently with the mitochondrial large ribosomal subunit RNA (LSU rRNA), a constituent of the mitochondrial large ribosomal subunit.
1990401	embryonic lung development	P	The process occurring during the embryonic phase whose specific outcome is the progression of the lung over time, from its formation to the mature structure.
1990402	embryonic liver development	P	The process occurring during the embryonic phase whose specific outcome is the progression of the liver over time, from its formation to the mature structure.
1990403	embryonic brain development	P	The process occurring during the embryonic phase whose specific outcome is the progression of the brain over time, from its formation to the mature structure.
1990404	protein ADP-ribosylase activity	F	The transfer, from NAD, of ADP-ribose to a protein amino acid residue.
1990405	protein antigen binding	F	Interacting selectively and non-covalently with a protein antigen.
1990406	CGRP receptor complex	C	A transmembrane, G-protein-coupled signalling receptor complex recognized by calcitonin gene-related peptides (CGRP).
1990407	calcitonin gene-related peptide binding	F	Interacting selectively and non-covalently with calcitonin gene-related peptide (CGRP).
1990408	calcitonin gene-related peptide receptor signaling pathway	P	A series of molecular signals initiated by an extracellular calcitonin gene-related peptide (CGRP) combining with a calcitonin gene-related peptide receptor on the surface of the target cell. Calcitonin gene-related peptide receptors may form dimers, trimers or tetramers.
1990409	adrenomedullin binding	F	Interacting selectively and non-covalently with adrenomedullin (AM).
1990410	adrenomedullin receptor signaling pathway	P	A series of molecular signals initiated by an extracellular adrenomedullin combining with a dimeric adrenomedullin receptor on the surface of the target cell.
1990411	hercynylcysteine sulfoxide lyase activity (ergothioneine-forming)	F	Catalysis of the reaction: hercynylcysteine sulfoxide + 2H+ = ergothioneine + pyruvate + ammonium.
1990412	hercynylselenocysteine lyase activity (selenoneine-forming)	F	Catalysis of the reaction: hercynylselenocysteine + 2H+ = selenoneine + pyruvate + ammonium.
1990413	eyespot apparatus	C	A small pigmented organelle used in single-celled organisms to detect light.
1990414	replication-born double-strand break repair via sister chromatid exchange	P	The repair of a replication-born double-strand DNA break in which the DNA molecule is repaired using the homologous sequence of the sister chromatid which serves as a template to repair the breaks.
1990415	Pex17p-Pex14p docking complex	C	A protein complex involved in the peroxisomal import machinery. In S. cerevisiae, this complex contains the proteins Pex17p, Pex14p, Pex19, and Pex13p.
1990416	cellular response to brain-derived neurotrophic factor stimulus	P	A process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a brain-derived neurotrophic factor stimulus.
1990417	snoRNA release from pre-rRNA	P	The release of snoRNA from pre-rRNA.
1990418	response to insulin-like growth factor stimulus	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an insulin-like growth factor stimulus.
1990420	establishment of septation initiation network asymmetry	P	The septation initiation signaling process by which the activity of the septation initiation network (SIN) is activated asymmetrically on the spindle pole bodies.
1990421	subtelomeric heterochromatin	C	Heterochromatic regions of the chromosome found at the subtelomeric regions.
1990422	glyoxalase (glycolic acid-forming) activity	F	Catalysis of the reaction: glyoxal + H2O = glycolic acid. Catalysis occurs in the absence of a cofactor.
1990423	RZZ complex	C	A kinetochore component required for both meiotic and mitotic spindle assembly checkpoints.
1990424	protein arginine kinase activity	F	Catalysis of the reaction: ATP + a protein arginine = ADP + protein arginine phosphate.
1990425	ryanodine receptor complex	C	A voltage-gated calcium-release channel complex of the sarcoplasmic or endoplasmic reticulum. It plays an important role in the excitation-contraction (E-C) coupling of muscle cells. RyR comprises a family of ryanodine receptors, widely expressed throughout the animal kingdom.
1990426	mitotic recombination-dependent replication fork processing	P	Replication fork processing that includes recombination between DNA near the arrested fork and homologous sequences. Proteins involved in homologous recombination are required for replication restart.
1990427	stereocilia tip-link density	C	An electron-dense plaque at either end of a stereocilia tip link that provides the anchor in the stereocilia membrane.
1990428	miRNA transport	P	The directed movement of microRNA (miRNA) into, out of or within a cell, or between cells, or within a multicellular organism by means of some agent such as a transporter or pore.
1990429	peroxisomal importomer complex	C	A protein complex responsible for transporting proteins into the peroxisomal matrix. An example of this complex is Pex14 found in S. cerevisae which has 9 core components and 12 transient interaction partners.
1990430	extracellular matrix protein binding	F	Interacting selectively and non-covalently with a protein that is part of an extracellular matrix.
1990431	priRNA 3'-end processing	P	The process of forming the mature 3' end of a priRNA molecule.
1990432	siRNA 3'-end processing	P	The process of forming the mature 3' end of a siRNA molecule.
1990433	CSL-Notch-Mastermind transcription factor complex	C	A DNA binding transcription factor complex consisting of CSL and mastermind proteins in complex with the cleaved, intracellular domain of Notch. It is required for both repression and activation of Notch target genes.
1990434	lower tip-link density	C	An electron-dense plaque at the lower end of a stereocilia tip link that provides the anchor in the stereocilia membrane at the tip of the stereocilium from which the tip link rises.
1990435	upper tip-link density	C	An electron-dense plaque at the upper end of a stereocilia tip link that provides the anchor in the stereocilia membrane on the side of the stereocilium where the tip link ends.
1990437	snRNA 2'-O-methylation	P	The posttranscriptional addition of a methyl group to the 2' oxygen atom of a nucleotide residue in an snRNA molecule.
1990438	U6 2'-O-snRNA methylation	P	The posttranscriptional addition a methyl group to the 2'-oxygen atom of a nucleotide residue in an U6 snRNA molecule.
1990439	MAP kinase threonine phosphatase activity	F	Catalysis of the reaction: MAP kinase threonine phosphate + H2O = MAP kinase tyrosine + phosphate.
1990440	positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress	P	Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of an endoplasmic reticulum stress.
1990441	negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress	P	Any process that stops, prevents, or reduces the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of an endoplasmic reticulum stress.
1990442	intrinsic apoptotic signaling pathway in response to nitrosative stress	P	A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced in response to nitrosative stress; a state often resulting from exposure to high levels of nitric oxide (NO) or the highly reactive oxidant peroxynitrite, which is produced following interaction of NO with superoxide anions.
1990443	peptidyl-threonine autophosphorylation	P	The phosphorylation by a protein of one or more of its own threonine amino acid residues, or a threonine residue on an identical protein.
1990444	F-box domain binding	F	Interacting selectively and non-covalently with an F-box domain of a protein.
1990446	U1 snRNP binding	F	Interacting selectively and non-covalently with any part of a U1 small nuclear ribonucleoprotein particle.
1990447	U2 snRNP binding	F	Interacting selectively and non-covalently with any part of a U2 small nuclear ribonucleoprotein particle.
1990448	exon-exon junction complex binding	F	Interacting selectively and non-covalently with an exon-exon junction complex, a protein complex deposited by the spliceosome upstream of messenger RNA exon-exon junctions. The exon-exon junction complex provides a binding platform for factors involved in mRNA export and nonsense-mediated mRNA decay.
1990450	linear polyubiquitin binding	F	Interacting selectively and non-covalently with a linear polymer of ubiquitin. Linear ubiquitin polymers are formed by linking the amino-terminal methionine (M1) of one ubiquitin molecule to the carboxy-terminal glycine (G76) of the next.
1990451	cellular stress response to acidic pH	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in the homeostasis of organismal or cellular pH (with pH < 7). pH is a measure of the acidity or basicity of an aqueous solution.
1990452	Parkin-FBXW7-Cul1 ubiquitin ligase complex	C	A ubiquitin ligase complex containing Parkin (PARK2), the F-box protein FBXW7 (also called SEL-10) and a cullin from the Cul1 subfamily; substrate specificity is conferred by the F-box protein.
1990453	nucleosome disassembly/reassembly complex	C	A protein complex involved in the disassembly and subsequent reassembly of nucleosomes. It associates with the coding region of transcriptionally active genes where it interacts with the RNA polymerase II and affects its processivity during co-transcriptional RNA processing and maturation. It exists as a functionally independent part of the NuA4 complex.
1990454	L-type voltage-gated calcium channel complex	C	A type of voltage-dependent calcium channel responsible for excitation-contraction coupling of skeletal, smooth, and cardiac muscle. 'L' stands for 'long-lasting' referring to the length of activation.
1990455	PTEN phosphatase complex	C	A phospholipid phosphatase complex that catalyses the hydrolysis of the second messenger PtdIns (3,4,5)P3. Will also dephosphorylate PtdIns(3,4)P2, PtdIns3P, and Ins(1,3,4,5)P4. Dimerization is critical for its lipid phosphatase function.
1990456	mitochondrion-ER tethering	P	The attachment of the mitochondrion to specific sites on the endoplasmic reticulum, which may facilitate exchange of metabolites between the organelles.
1990457	pexophagosome	C	A membrane-bounded intracellular vesicle involved in the degradation of peroxisome by macropexophagy.
1990458	lipooligosaccharide binding	F	Interacting selectively and non-covalently with lipooligosaccharide. Lipooligosaccharides (LOSs) are the major glycolipids expressed on mucosal Gram-negative bacteria.
1990459	transferrin receptor binding	F	Interacting selectively and non-covalently with the transferrin receptor.
1990460	leptin receptor binding	F	Interacting selectively and non-covalently with the leptin receptor.
1990461	detoxification of iron ion	P	Any process that reduces or removes the toxicity of iron ion. These include transport of iron away from sensitive areas and to compartments or complexes whose purpose is sequestration of iron ion.
1990462	omegasome	C	Omega-shaped (as in the Greek capital letter) intracellular membrane-bounded organelle enriched in phosphatidylinositol 3-phosphate and dynamically connected to the endoplasmic reticulum. Omegasomes are the first step of the formation of autophagosomes via the pre-autophagosomal structures.
1990463	lateral cortical node	C	A protein complex that is anchored at the cortical face of the plasma membrane, and contains proteins involved in regulating cell cycle progression. In Schizosaccharomyces pombe, lateral cortical nodes are several megadaltons in size, and contain Slf1, which anchors the complex at the membrane, and the methyltransferase Skb1 in stoichiometric quantities, and may contain other proteins.
1990464	D-2-hydroxyacid dehydrogenase (quinone) activity	F	Catalysis of the reaction: (R)-2-hydroxyacid + a quinone = 2-oxoacid + a quinol.
1990465	aldehyde oxygenase (deformylating) activity	F	Catalysis of the reaction a long-chain aldehyde + O(2) + 2 NADPH = an alkane + formate + H(2)O + 2 NADP(+).
1990466	protein autosumoylation	P	The sumoylation by a protein of one or more of its own amino acid residues, or residues on an identical protein.
1990467	NuA3a histone acetyltransferase complex	C	A NuA3 complex that catalyzes the acetylation of Histone H3. In S. cerevisiae, this complex consists of Eaf6p, Nto1p, Sas3p, Taf14p, Yng1p and associates with H3K4me3 using Yng1p.
1990468	NuA3b histone acetyltransferase complex	C	A NuA3 complex that catalyzes the acetylation of Histone H3. In S. cerevisiae, this complex consists of Eaf6p, Nto1p, Sas3p, Taf14p, Pdp3 and associates with H3K4me3 via Pdp3p.
1990469	Rhino-Deadlock-Cutoff Complex	C	Protein complex found in Drosophila consisting of the gene products of cuff, del and rhi. It regulates the licensing of transcription of dual-strand PIWI interacting RNA (piRNA) source loci by binding to dual-strand-cluster chromatin, probably via the H3K9me3-binding activity of Rhi. Rhi binding brings the putative termination cofactor Cuff in close proximity to the nascent piRNA precursor transcript which it appears to protect from degradation.
1990470	piRNA cluster binding	F	Interacting selectively and non-covalently with piRNA clusters, double-stranded DNA regions that give rise to PIWI-interacting RNAs (piRNAs).
1990471	piRNA uni-strand cluster binding	F	Interacting selectively and non-covalently with uni-strand piRNA clusters, double-stranded DNA regions that give rise to PIWI-interacting RNAs (piRNAs) that map predominantly to only one strand and exhibit hallmarks of canonical Pol II transcription. Uni-strand piRNA clusters are found in many taxa.
1990472	piRNA dual-strand cluster binding	F	Interacting selectively and non-covalently with dual-strand piRNA clusters, double-stranded DNA regions that give rise to PIWI-interacting RNAs (piRNAs) where piRNAs originate from both DNA strands via noncanonical transcription.
1990473	ciliary targeting signal binding	F	Interacting selectively and non-covalently with a ciliary targeting sequence, a specific peptide sequence that acts as a signal to localize a membrane protein to the ciliary membrane.
1990474	synaptic vesicle, readily releasable pool	C	A synaptic vesicle belonging to the pool of vesicles that are the first to be released as a result of chemical or electrical stimulation e.g. by an action potential, have the highest presynaptic membrane fusion probability and correspond to about 1% of the total number of synaptic vesicles at a resting terminal bouton.
1990475	synaptic vesicle, recycling pool	C	A synaptic vesicle belonging to the pool that repopulate vacancies within the readily releasable pool (RRP) of synaptic vesicles, and require more significant stimuli than the RRP in order to release neurotransmitter; about 10-15% of the total number of synaptic vesicles at a resting terminal bouton are in this state.
1990476	synaptic vesicle, resting pool	C	A synaptic vesicle belonging to the pool that remain unreleased even after prolonged stimulation causes a saturating degree of vesicular turnover. 50-80% of the total number of synaptic vesicles at a resting terminal bouton are in this pool.
1990477	NURS complex	C	The nuclear RNA silencing (NURS) complex is a protein complex formed by Red1, Mtl1, Red5, Rmn1, Iss10/Pir1, and Ars2/Pir2 that regulates RNA degradation and histone H3 lysine 9 methylation. It is likely related to the human CBCN complex.
1990478	response to ultrasound	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ultrasonic stimulus.
1990481	mRNA pseudouridine synthesis	P	The intramolecular conversion of uridine to pseudouridine in an mRNA molecule.
1990482	sphingolipid alpha-glucuronosyltransferase activity	F	Catalysis of the reaction: UDP-glucuronate + inositol phosphorylceramide (IPC) = UDP + GlcA-IPC.
1990483	Clr6 histone deacetylase complex I''	C	A histone deacetylase complex involved in chromatin organization. In Schizosaccharomyces pombe this complex consists of Clr6, Nts1, Mug165, and Png3.
1990484	aerobic lactate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of lactate (2-hydroxypropanoic acid) in the presence of oxygen.
1990485	anaerobic lactate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of lactate (2-hydroxypropanoic acid) in the absence of oxygen.
1990486	anaerobic fatty acid catabolic process	P	The chemical reactions and pathways resulting in the breakdown of a fatty acid in the absence of oxygen. A fatty acid is any of the aliphatic monocarboxylic acids that can be liberated by hydrolysis from naturally occurring fats and oils. Fatty acids are predominantly straight-chain acids of 4 to 24 carbon atoms, which may be saturated or unsaturated; branched fatty acids and hydroxy fatty acids also occur, and very long chain acids of over 30 carbons are found in waxes.
1990487	anaerobic lignin catabolic process	P	The chemical reactions and pathways resulting in the breakdown of lignin in the absence of oxygen. Lignin is a class of polymers of phenylpropanoid units.
1990488	anaerobic cellulose catabolic process	P	The chemical reactions and pathways resulting in the breakdown of cellulose, a linear beta1-4 glucan of molecular mass 50-400 kDa with the pyranose units in the -4C1 conformation, in absence of oxygen.
1990489	anaerobic pectin catabolic process	P	The chemical reactions and pathways resulting in the breakdown of pectin, a polymer containing a backbone of alpha-1,4-linked D-galacturonic acid residues, in the absence of oxygen.
1990490	archaeal proton-transporting A-type ATPase complex	C	A large proton-transporting two-sector ATPase protein complex that catalyzes the synthesis or hydrolysis of ATP by a rotational mechanism, coupled to the transport of protons across a membrane and is found in Archaea.
1990491	methane biosynthetic process from methanol and hydrogen	P	The chemical reactions and pathways resulting in the formation of methane from methanol and hydrogen.
1990492	mitotic cell cycle checkpoint inhibiting CAR assembly	P	A Mad2-dependent mitotic cell cycle checkpoint which delays cytokinetic actinomycin ring assembly if there is a delay in early M-phase.
1990497	regulation of cytoplasmic translation in response to stress	P	Modulation of the frequency, rate or extent of cytoplasmic translation as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).
1990498	mitotic spindle microtubule	C	Any microtubule that is part of a mitotic spindle; anchored at one spindle pole.
1990499	raps-insc complex	C	Protein complex required for the asymmetric division of neuroblasts in Drosophila. Coordinates asymmetric localization of cell fate determinants with orientation of the mitotic spindle resulting in different daughter cells upon division. Localizes at the apical cortex of the neuroblast: Raps maintains, but does not initiate, Insc apically, while Insc segregates Raps asymmetrically. Complex appears to be conserved in mammals (composed of INSC and GPSM1 or GPSM2).
1990500	eif4e-cup complex	C	A protein complex that causes translational repression in Drosophila. Prevents assembly of ribosomes at the mRNA by interfacing with a sequence-specific RNA-binding protein leading to recruitment of the CCR4 complex and consequently, reduction of the mRNA's poly(A) tail length. The complex is also required for dorso-ventral pattern formation in the embryo.
1990501	exon-exon junction subcomplex mago-y14	C	Component of the core exon-exon-junction complex (EJC). Fairly conserved in eukaryotes; in Drosophila, consists of the Mago and Y14 (tsunagi) gene products. Important for coupling nuclear and cytoplasmic events in gene expression. Inhibits the ATPase activity of eIF4AIII (Q9VHS8) to ensure a stable association of the EJC core with the mRNA.
1990502	dense core granule maturation	P	Steps required to transform a dense core granule generated at the trans-Golgi network into a fully formed and transmissible dense core granule. Dense core granule maturation proceeds through clathrin-mediated membrane remodeling events and is essential for efficient processing of cargo within dense core granules as well as for removing factors that might otherwise interfere with dense core granule trafficking and exocytosis.
1990503	dendritic lamellar body	C	A specialized secretory organelle found in neurons and associated with the formation of dendrodendritic gap junctions.
1990504	dense core granule exocytosis	P	The secretion of molecules (e.g. neuropeptides, insulin-related peptides or neuromodulators such as serotonin and dopamine) contained within a membrane-bounced dense core granule by fusion of the granule with the plasma membrane of a cell in response to increased cytosolic calcium levels.
1990505	mitotic DNA replication maintenance of fidelity	P	Any maintenance of fidelity that is involved in mitotic cell cycle DNA replication.
1990506	mitotic DNA-dependent DNA replication	P	A DNA replication process that uses parental DNA as a template for the DNA-dependent DNA polymerases that synthesize the new strands during the mitotic cell cycle.
1990507	ATP-independent chaperone mediated protein folding	P	The process of inhibiting aggregation and assisting in the covalent and noncovalent assembly of single chain polypeptides or multisubunit complexes into the correct tertiary structure that is dependent on interaction with a chaperone, and independent of ATP hydrolysis.
1990508	CKM complex	C	Cyclin-dependent kinase complex which reversibly associates with the Mediator complex. In Saccharomyces cerevisiae it consists of SSN2, SSN3, SSN8 and SRB8.
1990509	PYM-mago-Y14 complex	C	Protein complex involved in the disassembly of Mago-Y14 from the spliced mRNA during first round of translation, independently of the translational machinery. Conserved from fission yeast to humans.
1990511	piRNA biosynthetic process	P	The chemical reactions and pathways resulting in the formation of piRNAs, Piwi-associated RNAs, a class of 24- to 30-nucleotide RNA derived from repeat or complex DNA sequence elements and processed by a Dicer-independent mechanism.
1990512	Cry-Per complex	C	Nuclear transcriptional repressor complex that is capable of negatively regulating CLOCK-BMAL-dependent transactivation of genes in a delayed negative feedback manner which generates circadian rhythms.
1990513	CLOCK-BMAL transcription complex	C	Transcription factor complex which interacts with E-box regulatory elements in target genes, including Period (Per1, Per2, Per3) and Cryptochrome (Cry1, Cry2), to activate their transcription during the daytime. The CRY-PER complexes inhibit CLOCK-BMAL1-driven transcription in a negative feedback loop to generate circadian rhythms.
1990514	5' transitive RNA interference	P	An RNA interference where the silencing signal spreads 5' along the target mRNA, outside of the initial target sequence. Typically involves the formation of secondary siRNAs formed when the initial mRNA target sequence functions as a template for 5' to 3' synthesis of new dsRNA.
1990515	3' transitive RNA interference	P	An RNA interference where the silencing signal spreads 3' along the target mRNA, outside of the initial target sequence. Typically involves the formation of secondary siRNAs formed when the initial mRNA target sequence functions as a template for 5' to 3' synthesis of new dsRNA.
1990516	ribonucleotide excision repair	P	The pathway by which a ribonucleotide is removed from DNA and replaced by a deoxyribonucleotide. The ribonucleotide is incised by RNase H2, and further excised by an endonuclease. The resulting 1 nt gap is then repaired by DNA polymerase and DNA ligase.
1990518	single-stranded DNA-dependent ATP-dependent 3'-5' DNA helicase activity	F	Catalysis of the reaction: ATP + H2O = ADP + phosphate, in the presence of single-stranded DNA; drives the unwinding of the DNA helix in the direction 3' to 5'.
1990519	mitochondrial pyrimidine nucleotide import	P	The directed movement of a pyrimidine nucleotide across the mitochondrial outer membrane into the mitochondria.
1990520	separase-securin complex	C	A protein complex that includes separase and securin as components and that inhibits chromosome separation at mitosis.
1990521	m7G(5')pppN diphosphatase activator activity	F	Binds to and increases the activity of m7G(5')pppN diphosphatase.
1990522	tail spike morphogenesis	P	The process in which the nematode tail spike is generated and organized. An example of this process is seen in C. elegans, where the tapered tail spike is formed during embryogenesis by a filamentous process that passes posteriorly through hyp10, the tail ventral hypodermis; the filamentous process is formed by a binucleate cell, the tail-spike cell, that subsequently undergoes programmed cell death.
1990523	bone regeneration	P	The regrowth of bone following its loss or destruction.
1990524	INA complex	C	A protein complex located in the inner membrane of mitochondria that is involved in the assembly of the peripheral (or stator) stalk of the mitochondrial proton-transporting ATP synthase (also known as the F1F0 ATP synthase). In budding yeast, this complex includes Ina22p and Ina17p.
1990525	BIR domain binding	F	Interacting selectively and non-covalently with a Baculovirus Inhibitor of apoptosis protein Repeat (BIR) domain.
1990526	Ste12p-Dig1p-Dig2p complex	C	A multiprotein complex that is involved in the transcription regulation of mating genes in the yeast S. cerevisiae.
1990527	Tec1p-Ste12p-Dig1p complex	C	A multiprotein complex that is involved in the transcriptional regulation of primarily filamentation genes, but also mating genes, in the yeast S. cerevisiae.
1990528	Rvs161p-Rvs167p complex	C	A protein complex that is involved in endocytosis in the yeast S. cerevisiae.
1990529	glycosylphosphatidylinositol-mannosyltransferase I complex	C	A protein complex that is involved in the transfer of the four mannoses in the GPI-anchor precursor. In yeast S. cerevisiae this complex consists of Pbn1p and Gpi14p and in rat this complex consists of PIG-X and PIG-M.
1990530	Cdc50p-Drs2p complex	C	A protein complex that assembles on the ER membrane and is essential for the ER exit of the Cdc50p-Drs2p complex.
1990531	Lem3p-Dnf1p complex	C	A protein complex that functions as a phospholipid-translocating P-Type ATPase.
1990532	stress response to nickel ion	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a disturbance in organismal or cellular homeostasis caused by a nickel ion stimulus.
1990533	Dom34-Hbs1 complex	C	A protein complex consisting of one subunit known as Dom34 or Pelota that has similarity to translation termination factor eRF1, and another subunit, Hbs1, that is a GTPase with similarity to translation termination factor eRF3. The Dom34-Hbs1 complex has a role in cotranslational mRNA quality control by promoting ribosomal subunit dissociation and peptidyl-tRNA release when translation is stalled, facilitating no-go decay and nonstop decay.
1990534	thermospermine oxidase activity	F	Catalysis of the reaction: S-methyl-5'-thioadenosine + thermospermine + H+ = S-adenosyl 3-(methylthio)propylamine + spermidine.
1990535	neuron projection maintenance	P	The organization process that preserves a neuron projection in a stable functional or structural state. A neuron projection is a prolongation or process extending from a nerve cell, e.g. an axon or dendrite.
1990536	phosphoenolpyruvate transmembrane import into Golgi lumen	P	The directed movement of phosphoenolpyruvate into the Golgi lumen across the Golgi membrane.
1990537	mitotic spindle polar microtubule	C	Any of the mitotic spindle microtubules that come from each pole and overlap at the spindle midzone.
1990538	xylan O-acetyltransferase activity	F	Catalysis of the reaction: acetyl-CoA + a xylan= CoA + an acetylated xylan.
1990539	fructose import across plasma membrane	P	The directed movement of fructose substance from outside of a cell, across the plasma membrane and into the cytosol.
1990540	mitochondrial manganese ion transmembrane transport	P	A process in which a manganese ion is transported from one side of a mitochondrial membrane to the other by means of some agent such as a transporter or pore.
1990541	mitochondrial citrate transmembrane transport	P	The directed movement of citrate, 2-hydroxy-1,2,3-propanetricarboyxlate, from one side of a membrane to the other into, out of or within a mitochondrion.
1990542	mitochondrial transmembrane transport	P	The process in which a solute is transported from one side of a membrane to the other into, out of or within a mitochondrion.
1990543	mitochondrial S-adenosyl-L-methionine transmembrane transport	P	The directed movement of S-adenosyl-L-methionine from one side of a membrane to the other into, out of or within a mitochondrion.
1990544	mitochondrial ATP transmembrane transport	P	The directed movement of ATP from one side of a membrane to the other into, out of or within a mitochondrion.
1990545	mitochondrial thiamine pyrophosphate transmembrane transport	P	The directed movement of thiamine pyrophosphate from one side of a membrane to the other into, out of or within a mitochondrion.
1990546	mitochondrial tricarboxylic acid transmembrane transport	P	The directed movement of a tricarboxylic acid from one side of a membrane to the other into, out of or within a mitochondrion.
1990547	mitochondrial phosphate ion transmembrane transport	P	The directed movement of phosphate ion from one side of a membrane to the other into, out of or within a mitochondrion.
1990548	mitochondrial FAD transmembrane transport	P	The directed movement of FAD from one side of a membrane to the other into, out of or within a mitochondrion.
1990549	mitochondrial NAD transmembrane transport	P	The directed movement of NAD from one side of a membrane to the other into, out of or within a mitochondrion.
1990550	mitochondrial alpha-ketoglutarate transmembrane transport	P	The directed movement of alpha-ketoglutarate from one side of a membrane to the other into, out of or within a mitochondrion.
1990551	mitochondrial 2-oxoadipate transmembrane transport	P	The directed movement of 2-oxoadipate from one side of a membrane to the other into, out of or within a mitochondrion.
1990553	mitochondrial 5'-adenylyl sulfate transmembrane transport	P	The directed movement of 5'-adenylyl sulfate from one side of a membrane to the other into, out of or within a mitochondrion.
1990554	mitochondrial 3'-phospho-5'-adenylyl sulfate transmembrane transport	P	The directed movement of 3'-phospho-5'-adenylyl sulfate from one side of a membrane to the other into, out of or within a mitochondrion.
1990555	mitochondrial oxaloacetate transmembrane transport	P	The directed movement of oxaloacetate from one side of a membrane to the other into, out of or within a mitochondrion.
1990556	mitochondrial isopropylmalate transmembrane transport	P	The directed movement of isopropylmalate from one side of a membrane to the other into, out of or within a mitochondrion.
1990557	mitochondrial sulfate transmembrane transport	P	The directed movement of sulfate from one side of a membrane to the other into, out of or within a mitochondrion.
1990558	mitochondrial malonate(1-) transmembrane transport	P	The directed movement of malonate(1-) from one side of a membrane to the other into, out of or within a mitochondrion.
1990559	mitochondrial coenzyme A transmembrane transport	P	The directed movement of coenzyme A from one side of a membrane to the other into, out of or within a mitochondrion.
1990561	regulation of transcription from RNA polymerase II promoter in response to copper ion starvation	P	Modulation of the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating the organism is deprived of copper ions.
1990562	syndecan-syntenin-ALIX complex	C	An exosome complex that is assembled in the multivesicular body (MVB) membrane and chaperoned to the exosome by the ESCRT-III machinery.
1990563	extracellular exosome complex	C	A protein complex that is wholly or partially contained within the lumen or membrane of the extracellular vesicular exosome.
1990564	protein polyufmylation	P	Covalent attachment of the ubiquitin-like protein UFM1 to a protein, forming an UFM1 chain.
1990565	HSP90-CDC37 chaperone complex	C	A protein complex involved in stress-induced mitophagy (mitochondrial degradation). In mammals it consists of heat shock protein HSP90 and its co-chaperone CDC37. Experimental evidence suggests that the complex enables the autophosphorylation of ULK1. Phosphorylated ULK1 in turn phosphorylates ATG13 which is an essential step in mitophagy. HSP90-CDC37 binding prevents rapid ubiquitin-dependent proteosomal degradation of its targets.
1990566	I(KACh) inward rectifier potassium channel complex	C	An inward rectifier potassium channel complex expressed in cardiac muscle, specifically the sinoatrial node and atria, where it controls the heart rate, via regulation by G-protein-coupled receptor signalling. In mammals it is composed of GIRK1 (or Kir3.1) and GIRK4 (or Kir3.4) subunits.
1990567	DPS complex	C	A protein serine/threonine phosphatase complex that in S. pombe consists of the proteins Dis2, Ppn1, and Swd22.
1990569	UDP-N-acetylglucosamine transmembrane transport	P	The directed movement of UDP-N-acetylglucosamine across a membrane.
1990570	GDP-mannose transmembrane transport	P	The directed movement of GDP-mannose across a membrane.
1990571	meiotic centromere clustering	P	The process by which centromeres/kinetochores become localized to clusters during a meiotic nuclear division. For example, in Schizosaccharomyces pombe, centromeres are located in one or two clusters away from the spindle pole body during meiosis.
1990572	TERT-RMRP complex	C	A ribonucleoprotein complex that has RNA-directed RNA polymerase (RdRP) activity, and is composed of telomerase reverse transcriptase (TERT) and the non-coding RNA component of mitochondrial RNA processing endoribonuclease (RMRP).
1990573	potassium ion import across plasma membrane	P	The directed movement of potassium ions from outside of a cell, across the plasma membrane and into the cytosol.
1990574	meiotic spindle astral microtubule	C	Any of the meiotic spindle microtubules that radiate in all directions from the spindle poles and are thought to contribute to the forces that separate the poles and position them in relation to the rest of the cell.
1990575	mitochondrial L-ornithine transmembrane transport	P	The directed movement of L-ornithine from one side of a membrane to the other into, out of or within a mitochondrion.
1990576	G-protein coupled glucose receptor activity	F	Combining with an extracellular glucose molecule and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.
1990577	C-terminal protein demethylation	P	The removal of a methyl group from the C-terminal amino acid of a protein.
1990578	perinuclear endoplasmic reticulum membrane	C	The membrane of the perinuclear endoplasmic reticulum, which is the portion of endoplasmic reticulum, the intracellular network of tubules and cisternae, that occurs near the nucleus.
1990579	peptidyl-serine trans-autophosphorylation	P	The phosphorylation of a peptidyl-serine to form peptidyl-O-phospho-L-serine on an identical protein. For example, phosphorylation by the other kinase within a homodimer.
1990580	regulation of cytoplasmic translational termination	P	Any process that modulates the frequency, rate or extent of cytoplasmic translational termination.
1990583	phospholipase D activator activity	F	Increases the activity of the enzyme phospholipase D.
1990584	cardiac Troponin complex	C	A complex of accessory proteins (cardiac troponin T, cardiac troponin I and cardiac troponin C) found associated with actin in cardiac muscle thin filaments; involved in calcium regulation important for muscle contraction.
1990585	hydroxyproline O-arabinosyltransferase activity	F	Catalysis of the reaction: UDP-beta-L-arabinofuranose + a [protein]-trans-4-hydroxy-L-proline <=> a protein-O-(beta-L-arabinofuranose)-trans-4-hydroxy-L-proline + UDP + H+.
1990586	divisome complex	C	A protein complex required for prokaryotic cell division (FtsZ-dependent cytokinesis). These complexes are assembled and recruited to the cell septum in a strictly controlled sequence and co-ordinate invagination of the cell membrane, inward growth of the peptidoglycan layer, constriction of the outer membrane and separation of daughter cells.
1990587	FtsQBL complex	C	A protein complex required for prokaryotic cell division (FtsZ-dependent cytokinesis). Part of the divisome. Assembled independently of the other divisome components in the cytoplasm prior to transport to the cell septum. In E. coli consists of FtsB, FtsL and FtsQ.
1990588	FtsBL complex	C	A protein complex required for prokaryotic cell division (FtsZ-dependent cytokinesis). Part of the divisome. Assembled independently of the other divisome components in the cytoplasm prior to transport to the cell septum. In E. coli consists of FtsB and FtsL.
1990589	ATF4-CREB1 transcription factor complex	C	Transcription factor complex consisting of ATF4 and CREB1 subunits that is capable of binding to cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3') as part of the positive regulation of transcription. Regulatory targets include the GRP78 (HSPA5) promoter in humans, whose activation by this complex is part of the ER stress response pathway.
1990590	ATF1-ATF4 transcription factor complex	C	Transcription factor complex consisting of ATF1 and ATF4 subunits that is capable of binding to cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3') of the GRP78 (HSPA5) promoter. Involved in the ER stress response pathway.
1990591	asparagine transmembrane import into vacuole	P	The directed movement of asparagine into the vacuole across the vacuolar membrane.
1990592	protein K69-linked ufmylation	P	A protein ufmylation process in which a polymer of the ubiquitin-like protein UFM1 is formed by linkages between lysine residues at position 69 of the UFM1 monomers, is added to a protein.
1990593	nascent polypeptide-associated complex binding	F	Interacting selectively and non-covalently with the nascent polypeptide-associated complex, which is a heterodimeric protein complex that can reversibly bind to ribosomes and is located in direct proximity to newly synthesized polypeptide chains as they emerge from the ribosome.
1990594	L-altrarate dehydratase activity	F	Catalysis of the reaction: L-altrarate = 5-dehydro-4-deoxy-D-glucarate + H(2)O.
1990595	mast cell secretagogue receptor activity	F	Combining with basic secretagogues to initiate pseudo-allergic reactions in mast cells.
1990596	histone H3-K4 deacetylation	P	The modification of histone H3 by the removal of an acetyl group from lysine at position 4 of the histone.
1990597	AIP1-IRE1 complex	C	A protein complex consisting of IRE1 (inositol-requiring enzyme-1) bound to AIP1 (ASK1-interacting protein 1/DAB2-interacting protein).
1990598	repair of mitotic mono-orientation defects	P	The mitotic cell cycle process where mono-orientation defects are corrected in order to ensure sister chromatids establish stable attachments to microtubules emanating from opposite spindle poles.
1990599	3' overhang single-stranded DNA endodeoxyribonuclease activity	F	Catalysis of the hydrolysis of ester linkages within 3' overhang single-stranded deoxyribonucleic acid by creating internal breaks.
1990600	single-stranded DNA endodeoxyribonuclease activator activity	F	Increases the activity of a single-stranded DNA endodeoxyribonuclease activator activity.
1990601	5' overhang single-stranded DNA endodeoxyribonuclease activity	F	Catalysis of the hydrolysis of ester linkages within 5' overhang single-stranded deoxyribonucleic acid by creating internal breaks.
1990602	importin alpha-subunit nuclear import complex	C	A trimeric protein complex which functions to shuttle the importin alpha-subunit into the nucleus through the nuclear pore to facilitate another round of mRNP incorporation and regulation. In Drosophila it consists of Cdm (Imp13), Mago and Tsu (Y14).
1990603	dark adaptation	P	The process by which the rods of the retina gradually become fully responsive to dim light when no longer exposed to bright light.
1990604	IRE1-TRAF2-ASK1 complex	C	A protein complex of the endoplasmic reticulum membrane that consists of IRE1 (Inositol-requiring enzyme-1), TRAF2 (TNF receptor-associated factor 2) and ASK1 (Apoptosis signal-regulating kinase 1, a MAP3K).
1990605	GU repeat RNA binding	F	Interacting selectively and non-covalently with an RNA molecule containing GU repeats.
1990606	membrane scission GTPase motor activity	F	Catalysis of the generation of a 'twisting' activity resulting in the scission of a membrane, coupled to the hydrolysis of a nucleoside triphosphate.
1990608	mitotic spindle pole body localization to nuclear envelope	P	A process in which a mitotic spindle pole body is transported to, or maintained in, a specific location in the nuclear envelope.
1990609	glutamate-cysteine ligase regulator activity	F	Binds to and modulates the activity of glutamate-cysteine ligase.
1990610	acetolactate synthase regulator activity	F	Binds to and modulates the activity of acetolactate synthase.
1990611	regulation of cytoplasmic translational initiation in response to stress	P	Modulation of the frequency, rate or extent of cytoplasmic translational initiation as a result of a stimulus indicating the organism is under stress. The stress is usually, but not necessarily, exogenous (e.g. temperature, humidity, ionizing radiation).
1990612	Sad1-Kms2 LINC complex	C	A LINC complex implicated in the connection of DNA double strand breaks to the cytoskeleton during DNA double-strand break repair.
1990613	mitochondrial membrane fusion	P	The joining of two lipid bilayers that surround the mitochondria.
1990614	mitochondrial magnesium ion transmembrane transport	P	A process in which a magnesium ion is transported from one side of a mitochondrial membrane to the other by means of some agent such as a transporter or pore.
1990615	Kelch-containing formin regulatory complex	C	A protein complex that regulates actin cable formation, polarized cell growth, and cytokinesis in a formin-dependent manner. In S. cerevisiae the complex is composed of Bud14p and two Kelch family proteins, Kel1p and Kel2p.
1990616	magnesium ion export from mitochondrion	P	The directed movement of magnesium ions out of mitochondria into the cytosol by means of some agent such as a transporter or pore.
1990617	CHOP-ATF4 complex	C	A heterodimeric transcription factor complex that is composed of CHOP (C/EBP homology protein, GADD153) and ATF4 (activating transcription factor 4, also known as cAMP response element binding protein-2/CREB-2) subunits.
1990619	histone H3-K9 deacetylation	P	The modification of histone H3 by the removal of an acetyl group from lysine at position 9 of the histone.
1990620	ANPR-A receptor complex	C	A receptor complex composed of two ANPR-A molecules and expressed in the heart atrium in mammals; it plays a major role in the regulation of blood pressure and salt-fluid volume homeostasis. Binding of the ligand AMP in response to atrial distension (high blood volume) leads to guanylate cyclase activity of the ANPR-A receptor complex, thereby elevating intracellular cGMP levels. The end result is a reduction in blood volume and, therefore, a reduction in cardiac output and systemic blood pressure.
1990621	Vps4-Vta1 complex	C	A protein complex involved in ESCRT-mediated intralumenal vesicle formation. The complex catalyzes disassembly of the ESCRT-III filament around the neck of the budding vesicle in an ATP-driven reaction, resulting in membrane scission and recycling of the ESCRT-III components back to the cytosol. In yeast, it is formed by the AAA ATPase Vps4 and its cofactor Vta1.
1990622	CHOP-ATF3 complex	C	A heterodimeric protein complex that is composed of CHOP (C/EBP homology protein, GADD153) and ATF3 (activating transcription factor 3) subunits.
1990623	Herring body	C	The dilated terminal portions of neurosecretory axons constituting the hypothalamohypophyseal tract, found in close proximity to sinusoidal capillaries in the posterior pituitary. Herring bodies consist of aggregates of membrane-bound neurosecretory vesicles where oxytocin or antidiuretic hormone (ADH) are stored prior to release. Each Herring body also contains ATP and either neurophysin I or neurophysin II which bind to oxytocin and ADH, respectively.
1990624	guanyl nucleotide exchange factor inhibitor activity	F	Stops, prevents or reduces the activity of a guanyl nucleotide exchange factor.
1990625	negative regulation of cytoplasmic translational initiation in response to stress	P	Any process that stops, prevents or reduces the rate of cytoplasmic translation initiation as a result of a stimulus indicating the organism is under stress.
1990626	mitochondrial outer membrane fusion	P	The membrane organization process that joins two mitochondrial outer membranes to form a single membrane.
1990627	mitochondrial inner membrane fusion	P	The membrane organization process that joins two mitochondrial inner membranes to form a single membrane.
1990629	phospholamban complex	C	A protein complex found as a homopentamer of the phospholamban (PLN) protein in the sarcoplasmic reticulum (SR) membrane of cardiomyocytes. Cardiac PLN is a main determinant of muscle contraction and relaxation, by regulating intracellular calcium levels.
1990630	IRE1-RACK1-PP2A complex	C	A protein complex consisting of IRE1 (Inositol-requiring enzyme-1), RACK1 (Receptor of activated protein kinase C 1, GNB2L1) and PP2A (protein phosphatase 2A). RACK1 acts as an adaptor to bridge an interaction between IRE1 and PP2A.
1990631	ErbB-4 class receptor binding	F	Interacting selectively and non-covalently with the protein-tyrosine kinase receptor ErbB-4/HER4.
1990632	branching involved in submandibular gland morphogenesis	P	The process in which the branching structure of the submandibular gland is generated and organized.
1990633	mutator focus	C	A type of punctate focus localized to the perinuclear region of germline cytoplasm in C. elegans. Mutator foci are required for RNA interference (RNAi) and serve as sites of small inhibitory RNA (siRNA) amplification. As such, proteins that localize to mutator foci include RNA-directed RNA polymerases (RdRPs) and beta-nucleotidyltransferases. Mutator foci are distinct from, but adjacent to or partially overlap, P granules.
1990634	protein phosphatase 5 binding	F	Interacting selectively and non-covalently with the enzyme protein phosphatase 5.
1990635	proximal dendrite	C	That part of the dendrite closest to the cell body of the neuron.
1990636	reproductive senescence	P	A natural reduction in reproductive capacity with aging, often taking the form of a switch from regular reproductive cycles to irregular and infrequent ones.
1990637	response to prolactin	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prolactin stimulus. The anterior pituitary hormone prolactin has a number of roles including being essential for lactation.
1990638	response to granulocyte colony-stimulating factor	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a granulocyte colony-stimulating factor stimulus.
1990640	inositol-2,4,5-triphosphate 5-phosphatase activity	F	Catalysis of the reaction: 1D-myo-inositol 2,4,5-trisphosphate + H2O = 1D-myo-inositol 2,4-bisphosphate + phosphate.
1990641	response to iron ion starvation	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a starvation stimulus, deprivation of iron ion.
1990643	cellular response to granulocyte colony-stimulating factor	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a granulocyte colony-stimulating factor stimulus.
1990644	microtubule site clamp	F	The binding activity of a molecule that attaches the spindle microtubules to the kinetochore.
1990646	cellular response to prolactin	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a prolactin stimulus.
1990647	C/EBP complex	C	A dimeric, sequence specific DNA-binding transcription factor complex regulating the expression of genes involved in immune and inflammatory responses. Exists at least as alpha and beta homodimeric forms. Binds to regulatory regions of several acute-phase and cytokines genes and probably plays a role in the regulation of acute-phase reaction, inflammation and hemopoiesis. The consensus recognition site is 5'-T[TG]NNGNAA[TG]-3'. Transcription factor activity is inhibited by binding of CHOP forming heterodimers with alternative transcription factor activities.
1990648	inositol-4,5,6-triphosphate 5-phosphatase activity	F	Catalysis of the reaction: 1D-myo-inositol 4,5,6-trisphosphate + H2O = 1D-myo-inositol 4,6-bisphosphate + phosphate.
1990649	inositol-1,2,4,5-tetrakisphosphate 5-phosphatase activity	F	Catalysis of the reaction: 1D-myo-inositol 1,2,4,5-tetrakisphosphate + H2O = 1D-myo-inositol 1,2,4-trisphosphate + phosphate.
1990650	inositol-2,4,5,6-tetrakisphosphate 5-phosphatase activity	F	Catalysis of the reaction: 1D-myo-inositol 2,4,5,6-tetrakisphosphate + H2O = 1D-myo-inositol 2,4,6-trisphosphate + phosphate.
1990651	inositol-1,2,4,5,6-pentakisphosphate 5-phosphatase activity	F	Catalysis of the reaction: 1D-myo-inositol 1,2,4,5,6-pentakisphosphate + H2O = 1D-myo-inositol 1,2,4,6-tetrakisphosphate + phosphate.
1990654	sebum secreting cell proliferation	P	The multiplication or reproduction of sebocytes by cell division, resulting in the expansion of their population. A sebocyte is an epithelial cell that makes up the sebaceous glands, and secrete sebum.
1990655	4 iron, 3 sulfur cluster binding	F	Interacting selectively and non-covalently with a 4 iron, 3 sulfur (4Fe-3S) cluster, an uncommon iron-sulfur cluster with unique properties found in oxygen-tolerant Ni-Fe hydrogenases of various bacteria.
1990656	t-SNARE clustering	P	The clustering process in which t-SNARES are localized to distinct domains in the cell membrane. t-SNAREs are cell surface proteins which are part of secretory microdomain assemblies.
1990657	iNOS-S100A8/A9 complex	C	A protein complex capable of stimulus-inducible nitric-oxide synthase activity. S-nitrosylates cysteine residues in target proteins, a principal mechanism of nitric oxide (NO)-mediated signal transduction. In mammals consists of NOS2, S100A8 and S100A9. S100A9 acts both as an adaptor linking NOS2 to its target and as a transnitrosylase that transfers the nitric oxide moiety from NOS2 to its target, via its own S-nitrosylated cysteine.
1990658	transnitrosylase complex	C	A transferase complex which is capable of transferring nitrogenous groups from one component to another.
1990659	sequestering of manganese ion	P	The process of binding or confining manganese ions such that they are separated from other components of a biological system.
1990660	calprotectin complex	C	A protein complex composed of S100A8 and S100A9 and capable of limiting Mn(2+) and Zn(2+) availability at sites of infection. Also binds Ca(2+). Expressed and released by neutrophils and epithelial cells, it exhibits broad-spectrum antimicrobial activity attributed to its metal-binding properties. Endogenous ligand of toll-like receptor 4 (TLR4) and of the receptor for advanced glycation end products (RAGE) initiating signal transduction through NF-kappa-B pathways.
1990661	S100A8 complex	C	A protein complex composed of a S100A8 dimer and capable of binding to toll-like receptor 4 (TLR4).
1990662	S100A9 complex	C	A protein complex composed of a S100A9 dimer and capable of binding to toll-like receptor 4 (TLR4) and the receptor for advanced glycation end products (RAGE) initiating signal transduction through NF-kappa-B pathways. Transports arachidonic acid between the cytosol and the NADPH oxidase complex at the plasma membrane in neutrophils as part of an inflammatory signal cascade leading to an oxidative burst. Complexes with microtubules to increase cell motility.
1990663	dihydroorotate dehydrogenase (fumarate) activity	F	Catalysis of the reaction: (S)-dihydroorotate + fumarate = orotate + succinate.
1990664	Nkx-2.5 complex	C	A transcription factor complex formed by two or more subunits of Nkx-2.5. Nkx-2.5 is an evolutionary conserved transcription factor important for the specification and differentiation of cardiomyocytes during heart development. It is also required for spleen development. It binds DNA either as a monomer, or a homodimer, or a heterodimer complex to activate or inhibit expression of genes.
1990665	AnxA2-p11 complex	C	A heterotetrameric protein complex comprising two Annexin A2 (AnxA2) monomers and two copies of its binding partner, S100 protein p11 (S100A10).
1990666	PCSK9-LDLR complex	C	A protein complex consisting of the serine protease PCSK9 (Proprotein convertase subtilisin/kexin-9) and a low-density lipoprotein receptor (LDLR). Interaction typically occurs through the epidermal growth factor-like repeat A (EGF-A) domain of the LDLR, and complex formation promotes degradation of the LDLR through the endosome/lysosome pathway.
1990667	PCSK9-AnxA2 complex	C	A protein complex consisting of the serine protease PCSK9 (Proprotein convertase subtilisin/kexin-9) and Annexin A2 (AnxA2).
1990668	vesicle fusion with endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane	P	The joining of the lipid bilayer membrane around a vesicle to the lipid bilayer membrane of the ERGIC. This can involve anterograde or retrograde transport vesicles.
1990669	endoplasmic reticulum-Golgi intermediate compartment (ERGIC) derived vesicle fusion with endoplasmic reticulum membrane	P	The joining of the lipid bilayer membrane around an ERGIC-derived vesicle to the lipid bilayer membrane of the ER. Such vesicles include COPI-coated transport vesicles involved in retrograde transport.
1990670	vesicle fusion with Golgi cis cisterna membrane	P	The joining of the lipid bilayer membrane around a vesicle to the lipid bilayer membrane around the Golgi cis cisterna. This can involve anterograde or retrograde transport vesicles.
1990671	vesicle fusion with Golgi medial cisterna membrane	P	The joining of the lipid bilayer membrane around a vesicle to the lipid bilayer membrane around the Golgi medial cisterna. This can involve anterograde or retrograde transport vesicles.
1990672	medial-Golgi-derived vesicle fusion with Golgi trans cisterna membrane	P	The joining of the lipid bilayer membrane around a medial-Golgi-derived vesicle to the lipid bilayer membrane around the Golgi trans cisterna. Vesicles are involved in anterograde transport.
1990673	intrinsic component of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane	C	The component of the ERGIC membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.
1990674	Golgi cis cisterna membrane	C	The lipid bilayer surrounding any of the thin, flattened compartments that form the cis portion of the Golgi complex.
1990675	Golgi medial cisterna membrane	C	The lipid bilayer surrounding any of the thin, flattened compartments that form the medial portion of the Golgi complex.
1990676	Golgi trans cisterna membrane	C	The lipid bilayer surrounding any of the thin, flattened compartments that form the trans portion of the Golgi complex.
1990677	mitochondrial inner membrane assembly complex	C	A protein complex that promotes the biogenesis of mitochondrial F1Fo-ATP synthase by facilitating assembly of the peripheral stalk. Loss of INAC function causes dissociation of the F1-domain from the membrane-integral Fo-portion.
1990678	histone H4-K16 deacetylation	P	The modification of histone H4 by the removal of an acetyl group from lysine at position 16 of the histone.
1990679	histone H4-K12 deacetylation	P	The modification of histone H4 by the removal of an acetyl group from lysine at position 12 of the histone.
1990680	response to melanocyte-stimulating hormone	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a melanocyte-stimulating hormone stimulus. The binding of any one of three melanocyte-stimulating hormones causes dispersal of melanosomes in melanophores of poikilothermic vertebrates.
1990682	CSF1-CSF1R complex	C	A protein complex consisting of a macrophage colony-stimulating factor (CSF1, also called M-CSF) dimer bound to a dimerized receptor (CSF1R, also called FMS). Receptor dimerization requires the presence of the ligand.
1990683	DNA double-strand break attachment to nuclear envelope	P	A process in which the DNA double-strand breaks are attached to the inner surface of the nuclear envelope proximal to the spindle pole body, or iMTOCs.
1990684	protein-lipid-RNA complex	C	A macromolecular complex containing separate protein, lipid and RNA molecules. Separate in this context means not covalently bound to each other.
1990685	HDL-containing protein-lipid-RNA complex	C	A protein-lipid-RNA complex containing separate high-density lipoprotein (HDL), lipid and RNA molecules. Separate in this context means not covalently bound to each other.
1990686	LDL-containing protein-lipid-RNA complex	C	A protein-lipid-RNA complex containing separate low-density lipoprotein (LDL), lipid and RNA molecules. Separate in this context means not covalently bound to each other.
1990687	endoplasmic reticulum-derived vesicle fusion with endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane	P	The joining of the lipid bilayer membrane around an endoplasmic reticulum-derived vesicle to the lipid bilayer membrane of the ERGIC. Such vesicles include COPII-coated transport vesicles involved in anterograde transport.
1990688	Golgi vesicle fusion with endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane	P	The joining of the lipid bilayer membrane around a Golgi vesicle to the lipid bilayer membrane of the ERGIC. Such vesicles include COPI-coated transport vesicles involved in retrograde transport.
1990689	endoplasmic reticulum-Golgi intermediate compartment (ERGIC) derived vesicle fusion with Golgi cis cisterna membrane	P	The joining of the lipid bilayer membrane around an ERGIC-derived vesicle to the lipid bilayer membrane around the Golgi cis cisterna. Such vesicles include COPII-coated transport vesicles involved in anterograde transport.
1990690	Golgi medial cisterna-derived vesicle fusion with Golgi cis cisterna membrane	P	The joining of the lipid bilayer membrane around a Golgi medial cisterna-derived vesicle to the lipid bilayer membrane around the Golgi cis cisterna. Such vesicles include COPI-coated transport vesicles involved in retrograde transport.
1990691	cis-Golgi-derived vesicle fusion with Golgi medial cisterna membrane	P	The joining of the lipid bilayer membrane around a cis-Golgi-derived vesicle to the lipid bilayer membrane around the medial-Golgi cisterna. Vesicles are involved in anterograde transport.
1990692	trans-Golgi-derived vesicle fusion with Golgi medial cisterna membrane	P	The joining of the lipid bilayer membrane around a trans-Golgi-derived vesicle to the lipid bilayer membrane around the medial-Golgi cisterna. Such vesicles include COPI-coated transport vesicles involved in retrograde transport.
1990693	intrinsic component of Golgi cis cisterna membrane	C	The component of the Golgi cis cisterna membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.
1990694	intrinsic component of Golgi medial cisterna membrane	C	The component of the Golgi medial cisterna membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.
1990695	intrinsic component of Golgi trans cisterna membrane	C	The component of the Golgi trans cisterna membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.
1990696	USH2 complex	C	A protein complex composed of four proteins, loss of which results in Usher Syndrome type 2 (USH2 syndrome), a leading genetic cause of combined hearing and vision loss. This complex is conserved in many species; in mice, it is composed of USH2A, GPR98 (aka ADGRV1), WHRN, and PDZD7.
1990697	protein depalmitoleylation	P	The removal of palmitoleyl group, a 16-carbon monounsaturated fatty acid (C16:1), from a lipoprotein.
1990698	palmitoleoyltransferase activity	F	Catalysis of the transfer of a palmitoleyl group, a 16-carbon monounsaturated fatty acid (C16:1), to an acceptor molecule.
1990699	palmitoleyl hydrolase activity	F	Catalysis of a hydrolase reaction that removes a palmitoleyl moiety, a 16-carbon monounsaturated fatty acid (C16:1), from some substrate.
1990700	nucleolar chromatin organization	P	Any process that results in the specification, formation or maintenance of the physical structure of nucleolar chromatin.
1990701	integral component of endoplasmic reticulum-Golgi intermediate compartment (ERGIC) membrane	C	The component of the ERGIC membrane consisting of the gene products having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
1990702	integral component of Golgi cis cisterna membrane	C	The component of the Golgi cis membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
1990703	integral component of Golgi medial cisterna membrane	C	The component of the Golgi medial membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
1990704	integral component of Golgi trans cisterna membrane	C	The component of the Golgi trans membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
1990705	cholangiocyte proliferation	P	The multiplication or reproduction of cholangiocytes, resulting in the expansion of the cholangiocyte population. A cholangiocyte is an epithelial cell that is part of the bile duct. Cholangiocytes contribute to bile secretion via net release of bicarbonate and water.
1990706	MAD1 complex	C	A protein complex involved in the assembly of the mitotic checkpoint complex that in turn inhibits the anaphase promoting complex/cyclosome (APC/C).
1990707	nuclear subtelomeric heterochromatin	C	Heterochromatic regions of the chromosome found at the subtelomeric regions of a chromosome in the nucleus.
1990708	conditioned place preference	P	The associative learning process by which an animal learns and remembers an association between a neutral, unchanging environment and a putatively rewarding, internal state produced by a xenobiotic or drug.
1990709	presynaptic active zone organization	P	A process that results in the assembly, arrangement of constituent parts, or disassembly of a presynaptic active zone.
1990710	MutS complex	C	A homodimeric mismatch repair complex involved in binding to and correcting insertion/deletion mutations.
1990711	Beta-catenin-ICAT complex	C	Transcription factor complex that inhibits binding of Tcf to beta-catenin while preserving interaction of catenin with cadherin thus inhibiting transcription mediated by beta-catenin-Tcf complex.
1990712	HFE-transferrin receptor complex	C	A protein complex containing at least HFE and a transferrin receptor (either TFR1/TFRC or TFR2), proposed to play a role in the sensing of transferrin-bound Fe (Fe2-Tf) on the plasma membrane to regulate hepcidin transcription.
1990713	survivin complex	C	A protein complex that negatively regulates apoptotic processes. In human, this anti-apoptotic complex is a homodimer of BIRC5 (survivin) and provides one survivin molecule to the chromosomal passenger complex (CPC).
1990714	hydroxyproline O-galactosyltransferase activity	F	Catalysis of the transfer of galactose from UDP-galactose to hydroxyproline residues present in the peptide backbone.
1990715	mRNA CDS binding	F	Interacting selectively and non-covalently with the coding sequence (CDS) of an mRNA molecule.
1990716	axonemal central apparatus	C	Part of the 9+2 axoneme, that occurs in most motile cilia, consisting of the pair of two single central microtubules and their associated structures which include the central pair projections, the central pair bridges linking the two tubules, and the central pair caps which are attached to the distal or plus ends of the microtubules.
1990717	axonemal central bridge	C	Part of the 9+2 axoneme, that occurs in most motile cilia, consisting of the two bridges which connect the central pair of single microtubules.
1990718	axonemal central pair projection	C	Part of the 9+2 axoneme, that occurs in most motile cilia, consisting of the projections off of the central pair of single microtubules.
1990719	C1 axonemal microtubule	C	One of two microtubules present in the axonemal central pair. It is distinguishable from the C2 axonemal microtubule (also called C2 tubule) by the presence of differing protein components of the projections.
1990720	C2 axonemal microtubule	C	One of two microtubules present in the axonemal central pair. It is distinguishable from the C1 axonemal microtubule (also called C1 tubule) by the presence of differing protein components of the projections.
1990722	DAPK1-calmodulin complex	C	A serine/threonine protein kinase complex involved in cell survival, apoptosis and autophagic cell death pathways. DAPK1 is activated by the dephosphorylation of a n-terminal serine and calcium-calmodulin binding.
1990723	cytoplasmic periphery of the nuclear pore complex	C	Cytoplasm situated in close proximity to a nuclear pore complex.
1990724	galectin complex	C	A homodimeric protein complex that is capable of binding a range of carbohydrates and is involved in anti-inflammatory and pro-apoptotic processes.
1990725	cord factor receptor activity	F	Combining with a cord factor, an M. tuberculosis cell wall glycolipid, and transmitting a signal from one side of the membrane to the other to initiate a change in cell activity.
1990726	Lsm1-7-Pat1 complex	C	A conserved protein complex that plays an important role in coupling deadenylation and decapping in the 5'-to-3' mRNA decay pathway. An example is found in S. cerevisiae.
1990727	tubulin folding cofactor complex	C	A multimeric protein complex involved in tubulin alpha-beta-subunit folding assembly consisting of beta-tubulin-TFC-D, alpha-tubulin-TFC-E and TFC-C, through which tubulin subunit association and dimer release occur.
1990728	mitotic spindle assembly checkpoint MAD1-MAD2 complex	C	A protein complex involved in the assembly of the mitotic checkpoint complex that in turn inhibits the anaphase promoting complex/cyclosome (APC/C). The MAD1 dimer recruits the open form of MAD2 (O-MAD2) turning it into the closed form (C-MAD2) upon binding. C-MAD2 inhibits CDC20, a member of the APC/C, upon release from the MAD1-MAD2 complex.
1990729	primary miRNA modification	P	The covalent alteration of one or more nucleotides within a primary miRNA molecule to produce a primary miRNA molecule with a sequence that differs from that coded genetically.
1990730	VCP-NSFL1C complex	C	A protein complex between the ATPase VCP (p97) and its cofactor p47 (NSFL1C). In human, the protein complex consists of one homotrimer of NSFL1C/p47 per homohexamer of VCP/p97.
1990731	UV-damage excision repair, DNA incision	P	A process that results in the endonucleolytic cleavage of the damaged strand of DNA immediately 5' of a UV-induced damage site, and is the first part of a DNA repair process that acts on both cyclobutane pyrimidine dimers (CPDs) and pyrimidine-pyrimidone 6-4 photoproducts (6-4PPs).
1990732	pyrenoid	C	A non-membrane-bounded organelle found within the chloroplasts of algae and hornworts; responsible for carbon dioxide fixation.
1990733	titin-telethonin complex	C	A protein complex formed between the N-terminus of the giant sarcomeric filament protein titin and the Z-disk ligand, telethonin. The complex is part of the Z-disk of the skeletal and cardiac sarcomere. Telethonin binding to titin might be essential for the initial assembly, stabilization and functional integrity of the titin filament, and hence important for muscle contraction relaxation in mature myofibrils.
1990734	astral microtubule anchoring at mitotic spindle pole body	P	Any process in which an astral microtubule is maintained in a specific location in a cell by attachment to a mitotic spindle pole body. Microtubules attach to spindle pole bodies at the minus end.
1990735	gamma-tubulin complex localization to mitotic spindle pole body	P	Any process in which a gamma-tubulin complex is transported to, or maintained in, a specific location at a mitotic spindle pole body.
1990736	regulation of vascular smooth muscle cell membrane depolarization	P	Any process that modulates the establishment or extent of a membrane potential in the depolarizing direction away from the resting potential in a vascular smooth muscle cell.
1990737	response to manganese-induced endoplasmic reticulum stress	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of endoplasmic reticulum stress caused by a manganese stimulus.
1990738	pseudouridine 5'-phosphatase activity	F	Catalysis of the reaction: pseudouridine 5'-phosphate + H2O = pseudouridine + phosphate.
1990739	granulosa cell proliferation	P	The multiplication or reproduction of granulosa cells, resulting in the expansion of the granulosa cells population. A granulosa cell is a supporting cell for the developing female gamete in the ovary of mammals. They develop from the coelomic epithelial cells of the gonadal ridge.
1990742	microvesicle	C	An extracellular vesicle released from the plasma membrane and ranging in size from about 100 nm to 1000 nm.
1990743	protein sialylation	P	A protein modification process that results in the addition of a sialic acid unit to the end of an oligosaccharide chain in a glycoprotein.
1990744	primary miRNA methylation	P	The posttranscriptional addition of methyl groups to specific residues in an primary miRNA molecule.
1990745	EARP complex	C	A quatrefoil tethering complex required for endocytic recycling.
1990746	HCN4 channel complex	C	HCN4 tetramer is a hyperpolarization-activated ion channel with selectivity for potassium over sodium ions. HCN4 is the dominant form of HCN expressed in the heart, together with HCN2. HCN4 expression is particularly high in the sinoatrial node, where impulses initiate and propagate throughout the heart. There is pharmacologic and genetic evidence that the HNC4 channel complex plays a role in cardiac pacemaking and automaticity, by contributing to the native pacemaker current of the heart (If). Mutations in the C-terminus containing the C-linker and CNBD domain, which affect the expression or function of the HCN4 channel are known to cause arrhythmia or bradycardia.
1990747	pancreatic trypsinogen secretion	P	The regulated release of trypsinogen from the cells of the exocrine pancreas.
1990748	cellular detoxification	P	Any process carried out at the cellular level that reduces or removes the toxicity of a toxic substance. These may include transport of the toxic substance away from sensitive areas and to compartments or complexes whose purpose is sequestration of the toxic substance.
1990749	polynucleotide adenylyltransferase activator activity	F	Increases the activity of the enzyme polynucleotide adenylyltransferase.
1990751	Schwann cell chemotaxis	P	The directed movement of a Schwann cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis).
1990752	microtubule end	C	Any end of a microtubule. Microtubule ends differ in that the so-called microtubule plus-end is the one that preferentially grows by polymerization, with respect to the minus-end.
1990753	equatorial cell cortex	C	The region of the cell cortex in a mitotically dividing cell that flanks the central spindle and corresponds to the site of actomyosin ring formation that results in cleavage furrow formation and ingression.
1990755	mitotic spindle microtubule depolymerization	P	The removal of tubulin heterodimers from one or both ends of a microtubule that is part of the mitotic spindle.
1990756	protein binding, bridging involved in substrate recognition for ubiquitination	F	The binding activity of a molecule that brings together a ubiquitin ligase and its substrate. Usually mediated by F-box BTB/POZ domain proteins.
1990757	ubiquitin ligase activator activity	F	Binds to and increases the activity of a ubiquitin ligase.
1990758	mitotic sister chromatid biorientation	P	The mitotic cell cycle process in which sister chromatids establish stable, end-on attachments to the plus ends of microtubules emanating from opposite spindle poles, oriented such that separation can proceed. This is the final step in metaphase plate congression.
1990759	HCN2 channel complex	C	HCN2 is a member of the hyperpolarization-activated ion channel family, which shows selectivity for potassium over sodium ions. Channel gating is facilitated by cAMP binding to the cyclic nucleotide binding domain. HCN2 is the dominant form of HCN expressed in the heart, together with HCN4 (O70507). HCN2 shows significant expression in various regions of the heart, especially the ventricles. There is pharmacological and genetic evidence that HCN channels play a role in cardiac pacemaking and automaticity, by contributing to the native pacemaker current of the heart (If).
1990760	osmolarity-sensing cation channel activity	F	Enables the transmembrane transfer of a cation by a channel that opens when a change in the osmolarity occurs in the extracellular space of the cell in which the cation channel resides.
1990761	growth cone lamellipodium	C	A thin sheetlike process extended by the leading edge of an axonal or dendritic growth cone; contains a dense meshwork of actin filaments.
1990762	cytoplasmic alanyl-tRNA aminoacylation	P	The process of coupling alanine to alanyl-tRNA, catalyzed by alanyl-tRNA synthetase involved in cytoplasmic translation.
1990763	arrestin family protein binding	F	Interacting selectively and non-covalently with any member of the arrestin family, proteins involved in agonist-mediated desensitization of G-protein-coupled receptors.
1990764	myofibroblast contraction	P	The actin filament-based process in which cytoplasmic actin filaments slide past one another resulting in contraction of a myofibroblast.
1990765	colon smooth muscle contraction	P	A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry of the large intestine, exclusive of the rectum. The colon is that part of the large intestine that connects the small intestine to the rectum.
1990767	prostaglandin receptor internalization	P	The process that results in the uptake of a prostaglandin receptor into an endocytic vesicle.
1990768	gastric mucosal blood circulation	P	The flow of blood through the gastric mucosa of an animal, enabling the transport of nutrients and the removal of waste products.
1990769	proximal neuron projection	C	The portion of an axon or dendrite that is close to the neuronal cell body.
1990770	small intestine smooth muscle contraction	P	A process in which force is generated within smooth muscle tissue, resulting in a change in muscle geometry in the intestine between the stomach and the large intestine.
1990771	clathrin-dependent extracellular exosome endocytosis	P	The clathrin-mediated endocytosis of an extracellular exosome.
1990772	substance P secretion	P	The regulated release of substance P, a peptide hormone that is involved in neurotransmission, inflammation, and antimicrobial activity.
1990773	matrix metallopeptidase secretion	P	The regulated release of matrix metallopeptidases, a family of zinc-dependent endopeptidases that can degrade extracellular matrix proteins and process other types of proteins.
1990774	tumor necrosis factor secretion	P	The regulated release of tumor necrosis factor from a cell. Tumor necrosis factor is an inflammatory cytokine produced by macrophages/monocytes during acute inflammation and which is responsible for a diverse range of signaling events within cells, leading to necrosis or apoptosis.
1990775	endothelin secretion	P	The regulated release of endothelin from a cell. Endothelins are endothelium-derived vasoactive peptides involved in a variety of biological functions.
1990776	response to angiotensin	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an angiotensin stimulus. Angiotensin is any of three physiologically active peptides (angiotensin II, III, or IV) processed from angiotensinogen.
1990777	lipoprotein particle	C	A spherical particle containing non-covalently associated proteins and lipids. Examples are plasma lipoprotein particles which transport lipids in the blood or lymph.
1990778	protein localization to cell periphery	P	A process in which a protein is transported to, or maintained in, the cell periphery.
1990779	glycoprotein Ib-IX-V complex	C	A transmembrane signalling receptor complex found exclusively on platelets. Involved in haemostasis and thrombosis where it aids blood coagulation.
1990780	cytoplasmic side of dendritic spine plasma membrane	C	The leaflet of the plasma membrane that faces the cytoplasm and any proteins embedded or anchored in it or attached to its surface surrounding a dendritic spine.
1990781	response to immobilization stress combined with electrical stimulus	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electrical stimulus given while being held immobile.
1990782	protein tyrosine kinase binding	F	Interacting selectively and non-covalently with protein tyrosine kinase.
1990783	periphagosomal region of cytoplasm	C	Cytoplasm situated near, or occurring around, a phagosome.
1990784	response to dsDNA	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a double-stranded DNA stimulus.
1990785	response to water-immersion restraint stress	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of water immersion while being held immobile.
1990786	cellular response to dsDNA	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a double-stranded DNA stimulus.
1990787	negative regulation of hh target transcription factor activity	P	Any process that decreases the activity of a transcription factor that activates transcription of Hedgehog-target genes in response to Smoothened signaling. In Drosophila, Cubitus interruptus (Ci) is the only identified transcription factor so far in the Hedgehog signaling pathway. In vertebrates members of the Gli protein family are activated by Hedgehog signaling.
1990788	GLI-SUFU complex	C	A protein repressing GLI's transcription factor activity when SMO signalling is inactive. Upon ligand binding to the upstream receptor PTC (Patched) GLI dissociates from SUFU and activates transcription of hedgehog-target genes. In mammals it consists of SUFU and one of the GLI family proteins.
1990789	thyroid gland epithelial cell proliferation	P	The multiplication or reproduction of thyroid gland epithelial cells, resulting in the expansion of the thyroid gland epithelial cell population.
1990790	response to glial cell derived neurotrophic factor	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glial cell derived neurotrophic factor stimulus.
1990791	dorsal root ganglion development	P	The process whose specific outcome is the progression of a dorsal root ganglion over time, from its formation to the mature structure.
1990792	cellular response to glial cell derived neurotrophic factor	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a glial cell derived neurotrophic factor stimulus.
1990793	substance P secretion, neurotransmission	P	The controlled release of substance P by a cell, in which the substance P acts as a neurotransmitter.
1990794	basolateral part of cell	C	The region of a cell situated by the cell sides which interface adjacent cells and near the base. Often used in reference to animal polarized epithelial cells.
1990795	rod bipolar cell terminal bouton	C	A specialized region of the axon terminus portion of a rod bipolar axon. A rod bipolar cell is a neuron found in the retina and having connections with rod photoreceptor cells and neurons in the inner plexiform layer.
1990796	photoreceptor cell terminal bouton	C	A specialized region of the axon terminus portion of a photoreceptor cell axon. A photoreceptor cell is a neuron specialized to detect and transduce light.
1990798	pancreas regeneration	P	The regrowth of a destroyed pancreas.
1990799	mitochondrial tRNA wobble position uridine thiolation	P	The process in which a uridine residue at position 34 in the anticodon of a mitochondrial tRNA is post-transcriptionally thiolated at the C2 position. This process involves transfer of a sulfur from cysteine to position C2 by several steps.
1990801	protein phosphorylation involved in mitotic spindle assembly	P	Any protein phosphorylation that is involved in mitotic spindle assembly.
1990802	protein phosphorylation involved in DNA double-strand break processing	P	Any protein phosphorylation that is required for DNA double-strand break processing.
1990803	protein phosphorylation involved in protein localization to spindle microtubule	P	Any protein phosphorylation process involved in localizing a protein to the spindle microtubule.
1990804	protein phosphorylation involved in double-strand break repair via nonhomologous end joining	P	Any protein phosphorylation process that is required for double-strand break repair via nonhomologous end joining.
1990805	central cylinder	C	A scaffolding structure present within the inner region of the ciliary transition zone. The central cylinder lies between the outer doublet and inner singlet microtubules.
1990808	F-bar domain binding	F	Interacting selectively and non-covalently with an F-BAR domain of a protein, a domain of about 60 residues that occurs in a wide range of cytoskeletal proteins.
1990809	endoplasmic reticulum tubular network membrane organization	P	A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the endoplasmic reticulum (ER) tubular network membrane.
1990810	microtubule anchoring at mitotic spindle pole body	P	Any process in which a microtubule is maintained in a specific location in a cell by attachment to a mitotic spindle pole body. Microtubules attach to spindle pole bodies at the minus end.
1990811	Msd1-Wdr8-Pkl1 complex	C	A protein ternary complex that anchors microtubule minus ends to mitotic spindle pole bodies. The founding complex contains a microtubule anchoring protein (Msd1 in fission yeast), A WD-repeat Wdr8 family protein and and a minus end-directed kinesin.
1990812	growth cone filopodium	C	A thin, stiff protrusion extended by the leading edge of an axonal or dendritic growth cone.
1990813	meiotic centromeric cohesion protection	P	The process in which the association between sister chromatids of a replicated chromosome centromeric region is maintained during homologous chromosome segregation after cohesin is cleaved by separase along the arm regions.
1990814	DNA/DNA annealing activity	F	A nucleic acid binding activity that brings together complementary sequences of ssDNA so that they pair by hydrogen bonds to form a double-stranded DNA.
1990816	vacuole-mitochondrion membrane contact site	C	A zone of apposition between the vacuolar membrane and the mitochondrial outer membrane, important for transfer of lipids between the two organelles.
1990817	RNA adenylyltransferase activity	F	Catalysis of the template-independent extension of the 3'- end of an RNA strand by addition of one adenosine molecule at a time. Cannot initiate a chain 'de novo'. The primer, depending on the source of the enzyme, may be an RNA, or oligo(A) bearing a 3'-OH terminal group.
1990818	L-arginine transmembrane export from vacuole	P	The directed movement of L-arginine out of the vacuole, across the vacuolar membrane.
1990819	actin fusion focus	C	A focus at the mating projection tip where the cell wall is degraded during conjugation with cellular fusion. Actin filaments form an aster-like structure from this location.
1990820	response to mitotic DNA integrity checkpoint signaling	P	A process that occurs in response to signals generated as a result of mitotic DNA integrity checkpoint signaling.
1990821	high affinity glucose import	P	The directed, high-affinity movement of glucose into a cell by means of some agent such as a transporter or pore. In high-affinity transport the transporter is able to bind the solute even if it is only present at very low concentrations.
1990822	basic amino acid transmembrane transport	P	The directed movement of basic amino acids from one side of a membrane to the other.
1990823	response to leukemia inhibitory factor	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a leukemia inhibitory factor stimulus.
1990825	sequence-specific mRNA binding	F	Interacting selectively and non-covalently with messenger RNA (mRNA) of a specific nucleotide composition or a specific sequence motif.
1990826	nucleoplasmic periphery of the nuclear pore complex	C	Nucleoplasm situated in close proximity and peripheral to a nuclear pore complex.
1990827	deaminase binding	F	Interacting selectively and non-covalently with an enzyme that catalyzes the removal of an amino group from a substrate, producing ammonia (NH3).
1990828	hepatocyte dedifferentiation	P	The process in which a hepatocyte (specialized epithelial cell of the liver) loses the structural or functional features that characterize it in the mature organism, or some other relatively stable phase of the organism's life history. Under certain conditions, these cells can revert back to the features of the stem cells that were their ancestors.
1990829	C-rich single-stranded DNA binding	F	Interacting selectively and non-covalently with C-rich, single-stranded DNA.
1990830	cellular response to leukemia inhibitory factor	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a leukemia inhibitory factor stimulus.
1990831	cellular response to carcinoembryonic antigen	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a carcinoembryonic antigen stimulus. The carcinoembryonic antigens represent a family of glycoproteins
1990832	slow axonal transport	P	The directed slow movement of non-membranous molecules in nerve cell axons. It is comprised of a "slow component a" (SCa) and a "slow component b" (SCb) which differ in transport rates and protein composition.
1990833	clathrin-uncoating ATPase activity	F	Catalysis of the reaction: ATP + H2O = ADP + phosphate. Catalysis of the removal of clathrin from vesicle membranes, coupled to the hydrolysis of ATP.
1990834	response to odorant	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an odorant stimulus. An odorant is any substance capable of stimulating the sense of smell.
1990836	lysosomal matrix	C	A matrix composed of supramolecular assemblies of lysosomal enzymes and lipids which forms at a pH of 5.0 within the lysosome.
1990837	sequence-specific double-stranded DNA binding	F	Interacting selectively and non-covalently with double-stranded DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA, e.g. promotor binding or rDNA binding.
1990838	poly(U)-specific exoribonuclease activity, producing 3' uridine cyclic phosphate ends	F	Catalysis of 3' exonucleolytic cleavage of poly(U), to form poly(U)-N containing a 3' uridine cyclic phosphate (U>P).
1990839	response to endothelin	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an endothelin stimulus. Endothelin is any of three secretory vasoconstrictive peptides (endothelin-1, -2, -3).
1990840	response to lectin	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lectin stimulus. A lectin is a carbohydrate-binding protein, highly specific for binding sugar moieties.
1990841	promoter-specific chromatin binding	F	Interacting selectively and non-covalently with a section of chromatin that is associated with gene promoter sequences of DNA.
1990843	subsarcolemmal mitochondrion	C	A mitochondrion that occurs adjacent to the sarcolemma in striated muscle cells and responds in distinct ways to physiological triggers.
1990844	interfibrillar mitochondrion	C	A mitochondrion that occurs in between fibrils of striated muscle cells and responds in distinct ways to physiological triggers.
1990845	adaptive thermogenesis	P	The regulated production of heat in response to short term environmental changes, such as stress, diet or reduced temperature.
1990846	ribonucleoside-diphosphate reductase inhibitor activity	F	Binds to and stops, prevents or reduces the activity of ribonucleoside-diphosphate reductase.
1990847	peptide pheromone transmembrane export involved in conjugation with cellular fusion	P	The directed movement of a peptide pheromone across a membrane and out of a cell by a secretion or export pathway used solely for the export of peptide pheromones that contributes to a conjugation process that results in the union of cellular and genetic information from compatible mating types.
1990849	maintenance of vacuolar location	P	Any process in which the vacuole is maintained in a specific location within a cell and prevented from moving elsewhere.
1990850	H-gal-GP complex	C	A membrane glycoprotein complex with aspartyl proteinase and metalloproteinase activity which is expressed in the gut. An example of this is found in the nematode Haemonchus contortus.
1990851	Wnt-Frizzled-LRP5/6 complex	C	A protein complex containing a secreted Wnt protein associated with its receptor, Frizzled (Fz), and co-receptor low density lipoprotein receptor-related protein 5 (LRP5) or LRP6.
1990852	protein transport along microtubule to spindle pole body	P	The directed movement of a protein along a microtubule to the spindle pole body, mediated by motor proteins.
1990853	histone H2A SQE motif phosphorylation	P	The modification of histone H2A by the addition of an phosphate group to the serine residue in the SQE motif of the histone.
1990854	vacuole-ER tethering	P	The attachment of a lytic vacuole to the endoplasmic reticulum, which may facilitate exchange of metabolites between the organelles.
1990856	methionyl-initiator methionine tRNA binding	F	Interacting selectively and non-covalently with methionine-initator methionine tRNA.
1990858	cellular response to lectin	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lectin stimulus. A lectin is a carbohydrate-binding protein, highly specific for binding sugar moieties.
1990859	cellular response to endothelin	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an endothelin stimulus. Endothelin is any of three secretory vasoconstrictive peptides (endothelin-1, -2, -3).
1990860	Pho85-Pho80 CDK-cyclin complex	C	A cyclin dependent kinase (CDK) complex that contains a kinase subunit and a regulatory cyclin subunit. An example of this complex in budding yeast S. cerevisiae consists of the Pho85 kinase and the Pho80 cyclin.
1990861	Ubp3-Bre5 deubiquitination complex	C	A protein complex that cleaves ubiquitin from specific substrates. In the budding yeast Saccharomyces cerevisiae, this complex consists of Ubp3p and Bre5p.
1990862	nuclear membrane complex Bqt3-Bqt4	C	A protein complex that resides in the inner nuclear membrane and anchors telomeres to the nuclear envelope. In fission yeast, it is composed of Bqt3 and Bqt4.
1990863	acinar cell proliferation	P	The multiplication or reproduction of acinar cells, resulting in the expansion of a cell population. An acinar cell is a secretory cell that is grouped together with other cells of the same type to form grape-shaped clusters known as acini (singular acinus).
1990864	response to growth hormone-releasing hormone	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a growth hormone-releasing hormone stimulus. Growth hormone-releasing hormone regulates the release of growth hormone, as well as some pancreatic proteins, and possibly other proteins.
1990867	response to gastrin	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gastrin stimulus.
1990868	response to chemokine	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemokine stimulus.
1990869	cellular response to chemokine	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chemokine stimulus.
1990871	Vma12-Vma22 assembly complex	C	A protein complex that is involved in the assembly of the V-ATPase complex. In the budding yeast Saccharomyces cerevisiae, this complex consists of Vma12p and Vma22p.
1990872	negative regulation of sterol import by negative regulation of transcription from RNA polymerase II promoter	P	Any process that decreases the frequency, rate or extent of sterol import, by down regulation of transcription from an RNA polymerase II promoter.
1990873	intrinsic component of plasma membrane of cell tip	C	The component of the plasma membrane surrounding the cell tip consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the plasma membrane surrounding the cell tip or some other covalently attached group such as a GPI anchor that is similarly embedded in the plasma membrane surrounding the cell tip.
1990874	vascular smooth muscle cell proliferation	P	The multiplication or reproduction of vascular smooth muscle cells, resulting in the expansion of a cell population. A vascular smooth muscle cell is a non-striated, elongated, spindle-shaped cell found lining the blood vessels.
1990875	nucleoplasmic side of nuclear pore	C	The side of the nuclear pore complex (NPC) that faces the nucleoplasm.
1990876	cytoplasmic side of nuclear pore	C	The side of the nuclear pore complex (NPC) that faces the cytoplasm.
1990877	Lst4-Lst7 complex	C	A heterodimeric complex that functions as a GTPase-Activating Protein (GAP) Complex for members of the Rag family of GTPases. In the budding yeast, this complex contains Lst4 and Lst7, while the orthologous mammalian complex contains Follicular (FLCN) and either follicular interaction protein 1 (FNIP1) or FNIP2.
1990878	cellular response to gastrin	P	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gastrin stimulus.
1990879	CST complex	C	A complex formed by the association of Cdc13 (CTC1 in mammals) with Stn1 in yeast (OBFC1 in mammals) and Ten1 protein (also TEN1 in mammals) with single-stranded telomeric DNA. The CST complex plays a role in telomere protection.
1990880	cellular detoxification of copper ion	P	Any process that reduces or removes the toxicity of copper ions in a cell. These include transport of copper cations away from sensitive areas and to compartments or complexes whose purpose is sequestration.
1990882	rRNA acetylation	P	The modification of rRNA structure by addition of an acetyl group to rRNA. An acetyl group is CH3CO-, derived from acetic [ethanoic] acid.
1990883	rRNA cytidine N-acetyltransferase activity	F	Catalysis of the reaction: acetyl-CoA + cytidine = CoA + N4-acetylcytidine. The cytidine is within the polynucleotide chain of an rRNA.
1990884	RNA acetylation	P	The posttranscriptional addition of one or more acetyl groups to specific residues in an RNA molecule.
1990886	3,4-dihydroxy-5-polyprenylbenzoic acid O-methyltransferase activity	F	Catalysis of the reaction: 3,4-dihydroxy-5-polyprenylbenzoic acid + S-adenosyl-L-methionine = 3-methoxy-4-hydroxy-5-polyprenylbenzoic acid + S-adenosyl-L-homocysteine + H+.
1990887	2-polyprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinol O-methyltransferase activity	F	Catalysis of the reaction: 2-polyprenyl-3-methyl-5-hydroxy-6-methoxy-1,4-benzoquinol + S-adenosyl-L-methionine = ubiquinol-n + S-adenosyl-L-homocysteine + H+.
1990888	2-polyprenyl-6-hydroxyphenol O-methyltransferase activity	F	Catalysis of the reaction: 2-polyprenyl-6-hydroxyphenol + S-adenosyl-L-methionine = 2-polyprenyl-6-methoxyphenol + S-adenosyl-L-homocysteine + H+.
1990889	H4K20me3 modified histone binding	F	Interacting selectively and non-covalently with a histone H4 in which the lysine residue at position 20 has been modified by trimethylation.
1990890	netrin receptor binding	F	Interacting selectively and non-covalently with a netrin receptor.
1990891	mitotic sister chromatid arm separation	P	The cell cycle process in which sister chromatid arms are physically detached from each other during mitosis.
1990892	mitotic chromosome arm chromatin condensation	P	The cell cycle process in which chromosome arm chromatin structure is compacted prior to and during mitosis in eukaryotic cells.
1990893	mitotic chromosome centromere condensation	P	The cell cycle process in which centromere chromatin structure is compacted prior to and during mitosis.
1990895	regulation of protein localization to cell cortex of cell tip	P	Any process that modulates the frequency, rate or extent of protein localization to cell cortex of cell tip.
1990896	protein localization to cell cortex of cell tip	P	A process in which a protein is transported to, or maintained in, the cell cortex of the cell tip.
1990898	meiotic DNA double-strand break clipping	P	The process by which SPO11/Rec12-oligonucleotide complexes are removed from 5' DNA double-strand breaks induced during meiosis. Proteins involved in this process include the MRX/MRN complex and Sae2/Ctp1/RBBP8(CtIP).
1990899	meiotic DNA double-strand break resectioning	P	The process following clipping in double-strand break processing of SPO11 induced breaks, where long-tract single-stranded 3'-end DNA is generated from naked (SPO11 has been removed) 5' ends.
1990900	ciliary pocket collar	C	A constriction site at the junction of the plasma, flagellar and flagellar pocket membranes where the flagellum emerges from the cell body. Observed in some unicellular eukaryotic species such as Chlamydomonas, Giardia and Trypanosoma.
1990901	old cell pole	C	The cell pole distal from the most recent cell division. In rod-shaped bacteria, some experiments distinguish between the old and new cell poles after cell division.
1990902	new cell pole	C	The cell pole proximal to the most recent cell division. In rod-shaped bacteria, some experiments distinguish between the old and new cell poles after cell division.
1990903	extracellular ribonucleoprotein complex	C	An extracellular macromolecular complex containing both protein and RNA molecules.
1990904	ribonucleoprotein complex	C	A macromolecular complex containing both protein and RNA molecules.
1990905	dinoflagellate peduncle	C	A small, flexible, finger-like appendage located near the flagellar pores in some photosynthetic as well as nonphotosynthetic dinoflagellate species. Its functions are not fully understood, but it has been associated with feeding behavior (phagotrophy).
1990906	accessory outer segment	C	A cilium-like cell projection emanating from the inner segment and running alongside the outer segment of photoreceptors.
1990907	beta-catenin-TCF complex	C	A protein complex that contains beta-catenin and a member of the T-cell factor (TCF)/lymphoid enhancer binding factor (LEF) family of transcription factors.
1990909	Wnt signalosome	C	A multiprotein protein complex containing membrane-localized Wnt receptors and cytosolic protein complexes, which is capable of transmitting the Wnt signal. Contains at least a Wnt protein, LRP5 or LRP6, a member of the Frizzled (Fz) family, Axin and and a Dishevelled (DVL) protein.
1990910	response to hypobaric hypoxia	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension combined with low atmospheric pressure. Hypoxia is defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95% and hypobaric is defined as atmospheric pressure below 0.74 atm (greater than 2,500 m above sea level).
1990911	response to psychosocial stress	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of exposure to aversive or demanding psychological and social conditions that tax or exceed the behavioral resources of the organism.
1990913	sperm head plasma membrane	C	The plasma membrane that is part of the head section of a sperm cell.
1990914	integral component of periplasmic side of plasma membrane	C	The component of the plasma membrane consisting of the gene products that penetrate only the periplasmic side of the membrane.
1990915	structural constituent of ascospore wall	F	The action of a molecule that contributes to the structural integrity of an ascospore wall.
1990916	Isp3 layer of spore wall	C	The outermost layers of the spore wall, as described in Schizosaccharomyces pombe.
1990917	ooplasm	C	The cytoplasm of an ovum.
1990918	double-strand break repair involved in meiotic recombination	P	The repair of double-strand breaks in DNA via homologous and nonhomologous mechanisms to reform a continuous DNA helix that contributes to reciprocal meiotic recombination.
1990919	nuclear membrane proteasome anchor	F	Interacting selectively and non-covalently with a proteasome complex and a nuclear inner membrane, in order to maintain the nuclear membrane localization of the proteasome.
1990920	proteasome localization to nuclear periphery	P	Any process in which the proteasome is transported to, or maintained at the nuclear periphery.
1990922	hepatic stellate cell proliferation	P	The multiplication or reproduction of hepatic stellate cells, resulting in the expansion of a hepatic stellate cell population. Hepatic stellate cells are found in the perisinusoidal space of the liver, and are capable of multiple roles including storage of retinol, presentation of antigen to T cells (including CD1d-restricted NKT cells), and upon activation, production of extracellular matrix components. This cell type comprises approximately 8-15% of total cells in the liver.
1990923	PET complex	C	A protein complex that is composed of at least EXD1, TDRD12 and some PIWI protein. The complex is required for MILI slicing-triggered biogenesis and loading of MIWI2 piRNAs
1990925	mitochondrial iron ion transmembrane transport	P	The directed movement of iron ions from one side of a membrane into, out of or within a mitochondrion.
1990926	short-term synaptic potentiation	P	The process by which synaptic transmission, induced by the arrival of a spike (action potential) at a synapse, acts to increase the amount of neurotransmitter released in response to the arrival of subsequent spikes. This effect is seen when a train of closely space spikes arrives at a synapse with a low initial release probability. It occurs in a timeframe of tens to hundreds of milliseconds.
1990927	calcium ion regulated lysosome exocytosis	P	The process of secretion by a cell that results in the release of intracellular molecules contained within a lysosome by fusion of the vesicle with the plasma membrane of a cell, induced by a rise in cytosolic calcium-ion levels.
1990928	response to amino acid starvation	P	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of amino acids.
1990929	sulfoquinovosidase activity	F	Catalyzes the hydrolysis of terminal non-reducing alpha-sulfoquinovoside residues in alpha-sulfoquinovosyl diacylglycerides and alpha-sulfoquinovosyl glycerol, generating alpha-sulfoquinovose.
1990930	RNA N1-methyladenosine dioxygenase activity	F	Catalysis of the oxidative demethylation of N1-methyladenosine RNA, with concomitant decarboxylation of 2-oxoglutarate and releases oxidized methyl group on N1-methyladenosine as formaldehyde.
1990931	RNA N6-methyladenosine dioxygenase activity	F	Catalysis of the oxidative demethylation of N6-methyladenosine RNA, with concomitant decarboxylation of 2-oxoglutarate and releases oxidized methyl group on N6-methyladenosine as formaldehyde.
1990932	5.8S rRNA binding	F	Interacting selectively and non-covalently with 5.8S ribosomal RNA, a eukaryotic ribosomal RNA which forms a complex with 28S RNA.
1990933	microtubule cytoskeleton attachment to nuclear envelope	P	A process in which the microtubule cytoskeleton is attached to the nuclear envelope.
1990934	nucleolus-like body	C	A nuclear compartment containing significant amounts of non-nucleolar, spliceosomal components. It is commonly found in germinal vesicle (GV) stage oocytes, and is similar to both nucleoli and sphere organelles.
1990935	splicing factor binding	F	Interacting selectively and non-covalently with any protein involved in the process of removing sections of the primary RNA transcript to form the mature form of the RNA.
1990936	vascular smooth muscle cell dedifferentiation	P	The process in which a vascular smooth muscle cell (a non-striated, elongated, spindle-shaped cell found lining the blood vessels) loses the structural or functional features that characterize it in the mature organism, or some other relatively stable phase of the organism's life history. Under certain conditions, these cells can revert back to the features of the stem cells that were their ancestors.
1990937	xylan acetylation	P	The addition of one or more acetyl groups to a xylan molecule.
1990938	peptidyl-aspartic acid autophosphorylation	P	The phosphorylation by a protein of one or more of its own aspartate amino acid residues, or an aspartate residue on an identical protein.
1990939	ATP-dependent microtubule motor activity	F	Catalysis of movement along a microtubule, coupled to the hydrolysis of ATP.
1990941	mitotic spindle kinetochore microtubule	C	Any of the mitotic spindle microtubules that attach to the kinetochores of chromosomes by their plus ends, and maneuver the chromosomes during mitotic chromosome segregation.
1990942	mitotic metaphase chromosome recapture	P	A mechanism to recapture 'lost' chromosomes (chromosomes which have become detached from the spindle) during metaphase of mitotic chromosome segregation. Chromosomes with unattached kinetochores are migrated along (non polar) spindle microtubules to the mitotic spindle pole body by a combination of microtubule depolymerisation and 'kinetochore sliding' (migration of the chromosome along the microtubule). The chromosome subsequently migrates along the polar spindle microtubule to the metaphase plate.
1990943	mating type region replication fork barrier binding	F	Interacting selectively and non-covalently with the replication fork barrier found in the mating type region of fission yeast.
1990944	maintenance of spindle pole body localization	P	Any process in which a spindle pole body is maintained in a specific location. A spindle pole body is a type of microtubule organizing center found in fungal cells.
1990946	meiosis I/meiosis II transition	P	The cell cycle process in which a cell progresses from meiosis I to meiosis II.
1990947	exit from meiosis	P	Any process involved in the progression from anaphase/telophase of meiosis II to the creation of end products of meiosis, in which ploidy is reduced by half.
1990948	ubiquitin ligase inhibitor activity	F	Stops, prevents or reduces the activity of a ubiquitin ligase.
1990949	metaphase/anaphase transition of meiosis I	P	The cell cycle process in which a cell progresses from metaphase to anaphase as part of meiosis I.
1990950	metaphase/anaphase transition of meiosis II	P	The cell cycle process in which a cell progresses from metaphase to anaphase as part of meiosis II.
1990953	intramanchette transport	P	The movement of vesicles and protein complexes carried out by molecular motors, kinesins and dynein, along the microtubule tracks within the manchette and by myosin along actin filaments.
1990954	establishment of protein localization to meiotic spindle pole body	P	The directed movement of a protein to a specific location at the meiotic spindle pole body.
1990955	G-rich single-stranded DNA binding	F	Interacting selectively and non-covalently with G-rich, single-stranded DNA.
1990956	fibroblast chemotaxis	P	The directed movement of a fibroblast guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis).
1990957	NPHP complex	C	A protein complex that is located at the ciliary transition zone and consists of the NPHP4 and NPHP1 proteins. It acts as an organiser of the transition zone inner structure, specifically the Y-shaped links, in conjunction with the MKS complex. It is involved in ciliary protein trafficking and is required for correct functioning of the WNT and Hippo signaling pathways.
1990959	eosinophil homeostasis	P	The process of regulating the proliferation and elimination of eosinophils such that the total number of eosinophils within a whole or part of an organism is stable over time in the absence of an outside stimulus.
1990960	basophil homeostasis	P	The process of regulating the proliferation and elimination of basophils such that the total number of basophils within a whole or part of an organism is stable over time in the absence of an outside stimulus.
1990961	drug transmembrane export	P	The directed movement of drugs out of a cell or organelle across a membrane.
1990962	drug transport across blood-brain barrier	P	The directed movement of drugs passing through the blood-brain barrier.
1990963	establishment of blood-retinal barrier	P	Establishment of the barrier between the blood and the retina. The blood-retinal barrier is located at two levels, forming an outer barrier in the retinal pigment epithelium and an inner barrier in the endothelial membrane of the retinal vessels. Both these membranes have tight junctions of the "nonleaky" type.
1990964	actin cytoskeleton-regulatory complex	C	A protein complex probably required for the internalization of endosomes during actin-coupled endocytosis. Links the site of endocytosis to the cell membrane-associated actin cytoskeleton, coordinating ARP2/3 stimulation at the later stages of endocytosis. Present in the late endocytic coat.
1990965	cytosylglucuronate decarboxylase activity	F	Catalysis of the reaction: cytosylglucuronic acid + H(+) = cytosylarabinopyranose + CO(2).
1990966	ATP generation from poly-ADP-D-ribose	P	The process of generating ATP in the nucleus from poly-ADP-D-ribose. Nuclear ATP generation is required for extensive chromatin remodeling events that are energy-consuming.
1990967	multi-organism toxin transport	P	The directed movement of a toxin into, out of or within a cell, or between cells where two or more organisms of the same or different species are involved.
1990968	modulation by host of RNA binding by virus	P	A process in which a host organism modulates the frequency, rate or extent of a viral gene product binding to RNA.
1990969	modulation by host of viral RNA-binding transcription factor activity	P	A process in which a host organism modulates the frequency, rate or extent of the activity of a viral RNA-binding transcription factor.
1990970	trans-activation response element binding	F	Interacting selectively and non-covalently with a trans-activation response (TAR) element, a hairpin RNA structure located at the 5' end of all HIV-1 transcripts, and which is required for trans-activation of a viral promoter.
1990971	EMILIN complex	C	Glycoprotein complex of the C1q/TNF superfamily found in the extracellular matrix (ECM) where it is an important component of the elastic fiber system. A homotrimer that will combine to form supramolecular EMILIN structures.
1990972	multimerin complex	C	Glycoprotein complex of the C1q/TNF superfamily involved in cell adhesion. A homotrimer that will combine to form supramolecular Multimerin structures.
1990973	transmembrane actin-associated (TAN) line	C	A linear array of nuclear envelope membrane proteins composed of nesprin-2G and SUN2, which couple the nucleus to moving actin cables, resulting in rearward nuclear transport (away from the leading edge).
1990974	actin-dependent nuclear migration	P	The process whereby the centrosome is held at the cell center while the nucleus moves to the cell rear by actin retrograde flow resulting in the position of the centrosome between the nucleus and the leading edge of the cell.
1990975	establishment of protein localization to mitotic spindle pole body	P	The directed movement of a protein to a specific location at the mitotic spindle pole body.
1990976	protein transport along microtubule to mitotic spindle pole body	P	The directed movement of a protein along a microtubule to the mitotic spindle pole body, mediated by motor proteins.
1990983	tRNA demethylation	P	The removal of a methyl group from one or more residues within a tRNA molecule.
1990984	tRNA demethylase activity	F	Catalysis of the removal of a methyl group from one or more positions within a tRNA molecule.
1990986	DNA recombinase disassembly	P	The disaggregation of a DNA recombinase complex into its constituent strand exchange proteins (recombinases).
2000001	regulation of DNA damage checkpoint	P	Any process that modulates the frequency, rate or extent of a DNA damage checkpoint.
2000002	negative regulation of DNA damage checkpoint	P	Any process that stops, prevents, or reduces the frequency, rate or extent of a DNA damage checkpoint.
2000003	positive regulation of DNA damage checkpoint	P	Any process that activates or increases the frequency, rate or extent of a DNA damage checkpoint.
2000004	regulation of metanephric S-shaped body morphogenesis	P	Any process that modulates the frequency, rate or extent of metanephric S-shaped body morphogenesis.
2000005	negative regulation of metanephric S-shaped body morphogenesis	P	Any process that stops, prevents, or reduces the frequency, rate or extent of metanephric S-shaped body morphogenesis.
2000006	regulation of metanephric comma-shaped body morphogenesis	P	Any process that modulates the frequency, rate or extent of metanephric comma-shaped body morphogenesis.
2000007	negative regulation of metanephric comma-shaped body morphogenesis	P	Any process that stops, prevents, or reduces the frequency, rate or extent of metanephric comma-shaped body morphogenesis.
2000008	regulation of protein localization to cell surface	P	Any process that modulates the frequency, rate or extent of protein localization to the cell surface.
2000009	negative regulation of protein localization to cell surface	P	Any process that stops, prevents, or reduces the frequency, rate or extent of protein localization to the cell surface.
2000010	positive regulation of protein localization to cell surface	P	Any process that activates or increases the frequency, rate or extent of protein localization to the cell surface.
2000011	regulation of adaxial/abaxial pattern formation	P	Any process that modulates the frequency, rate or extent of adaxial/abaxial pattern formation.
2000012	regulation of auxin polar transport	P	Any process that modulates the frequency, rate or extent of auxin polar transport.
2000013	regulation of arginine biosynthetic process via ornithine	P	Any process that modulates the frequency, rate or extent of arginine biosynthetic process via ornithine.
2000014	regulation of endosperm development	P	Any process that modulates the frequency, rate or extent of endosperm development.
2000015	regulation of determination of dorsal identity	P	Any process that modulates the frequency, rate or extent of determination of dorsal identity.
2000016	negative regulation of determination of dorsal identity	P	Any process that stops, prevents, or reduces the frequency, rate or extent of determination of dorsal identity.
2000017	positive regulation of determination of dorsal identity	P	Any process that activates or increases the frequency, rate or extent of determination of dorsal identity.
2000018	regulation of male gonad development	P	Any process that modulates the frequency, rate or extent of male gonad development.
2000019	negative regulation of male gonad development	P	Any process that stops, prevents, or reduces the frequency, rate or extent of male gonad development.
2000020	positive regulation of male gonad development	P	Any process that activates or increases the frequency, rate or extent of male gonad development.
2000021	regulation of ion homeostasis	P	Any process that modulates the frequency, rate or extent of ion homeostasis.
2000022	regulation of jasmonic acid mediated signaling pathway	P	Any process that modulates the frequency, rate or extent of jasmonic acid mediated signaling pathway.
2000023	regulation of lateral root development	P	Any process that modulates the frequency, rate or extent of lateral root development.
2000024	regulation of leaf development	P	Any process that modulates the frequency, rate or extent of leaf development.
2000025	regulation of leaf formation	P	Any process that modulates the frequency, rate or extent of leaf formation.
2000026	regulation of multicellular organismal development	P	Any process that modulates the frequency, rate or extent of multicellular organismal development.
2000027	regulation of organ morphogenesis	P	Any process that modulates the frequency, rate or extent of animal organ morphogenesis.
2000028	regulation of photoperiodism, flowering	P	Any process that modulates the frequency, rate or extent of photoperiodism, flowering.
2000029	regulation of proanthocyanidin biosynthetic process	P	Any process that modulates the frequency, rate or extent of proanthocyanidin biosynthetic process.
2000030	regulation of response to red or far red light	P	Any process that modulates the frequency, rate or extent of response to red or far red light.
2000031	regulation of salicylic acid mediated signaling pathway	P	Any process that modulates the frequency, rate or extent of salicylic acid mediated signaling pathway.
2000032	regulation of secondary shoot formation	P	Any process that modulates the frequency, rate or extent of secondary shoot formation.
2000033	regulation of seed dormancy process	P	Any process that modulates the frequency, rate or extent of seed dormancy process.
2000034	regulation of seed maturation	P	Any process that modulates the frequency, rate or extent of seed maturation.
2000035	regulation of stem cell division	P	Any process that modulates the frequency, rate or extent of stem cell division.
2000036	regulation of stem cell population maintenance	P	Any process that modulates the frequency, rate or extent of stem cell population maintenance.
2000037	regulation of stomatal complex patterning	P	Any process that modulates the frequency, rate or extent of stomatal complex patterning.
2000038	regulation of stomatal complex development	P	Any process that modulates the frequency, rate or extent of stomatal complex development.
2000039	regulation of trichome morphogenesis	P	Any process that modulates the frequency, rate or extent of trichome morphogenesis.
2000040	regulation of planar cell polarity pathway involved in axis elongation	P	Any process that modulates the frequency, rate or extent of planar cell polarity pathway involved in axis elongation.
2000041	negative regulation of planar cell polarity pathway involved in axis elongation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of planar cell polarity pathway involved in axis elongation.
2000042	negative regulation of double-strand break repair via homologous recombination	P	Any process that stops, prevents, or reduces the frequency, rate or extent of double-strand break repair via homologous recombination.
2000043	regulation of cardiac cell fate specification	P	Any process that modulates the frequency, rate or extent of cardiac cell fate specification.
2000044	negative regulation of cardiac cell fate specification	P	Any process that stops, prevents, or reduces the frequency, rate or extent of cardiac cell fate specification.
2000045	regulation of G1/S transition of mitotic cell cycle	P	Any cell cycle regulatory process that controls the commitment of a cell from G1 to S phase of the mitotic cell cycle.
2000047	regulation of cell-cell adhesion mediated by cadherin	P	Any process that modulates the frequency, rate or extent of cell-cell adhesion mediated by cadherin.
2000048	negative regulation of cell-cell adhesion mediated by cadherin	P	Any process that stops, prevents, or reduces the frequency, rate or extent of cell-cell adhesion mediated by cadherin.
2000049	positive regulation of cell-cell adhesion mediated by cadherin	P	Any process that activates or increases the frequency, rate or extent of cell-cell adhesion mediated by cadherin.
2000050	regulation of non-canonical Wnt signaling pathway	P	Any process that modulates the frequency, rate or extent of non-canonical Wnt signaling pathway.
2000051	negative regulation of non-canonical Wnt signaling pathway	P	Any process that stops, prevents, or reduces the frequency, rate or extent of non-canonical Wnt signaling pathway.
2000052	positive regulation of non-canonical Wnt signaling pathway	P	Any process that activates or increases the frequency, rate or extent of non-canonical Wnt-activated signaling pathway.
2000053	regulation of Wnt signaling pathway involved in dorsal/ventral axis specification	P	Any process that modulates the frequency, rate or extent of Wnt signaling pathway involved in dorsal/ventral axis specification.
2000054	negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification	P	Any process that stops, prevents, or reduces the frequency, rate or extent of Wnt signaling pathway involved in dorsal/ventral axis specification.
2000055	positive regulation of Wnt signaling pathway involved in dorsal/ventral axis specification	P	Any process that activates or increases the frequency, rate or extent of Wnt signaling pathway involved in dorsal/ventral axis specification.
2000056	regulation of Wnt signaling pathway involved in digestive tract morphogenesis	P	Any process that modulates the frequency, rate or extent of Wnt signaling pathway involved in digestive tract morphogenesis.
2000057	negative regulation of Wnt signaling pathway involved in digestive tract morphogenesis	P	Any process that stops, prevents, or reduces the frequency, rate or extent of Wnt signaling pathway involved in digestive tract morphogenesis.
2000058	regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process	P	Any process that modulates the frequency, rate or extent of protein ubiquitination involved in ubiquitin-dependent protein catabolic process.
2000059	negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of protein ubiquitination involved in ubiquitin-dependent protein catabolic process.
2000060	positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process	P	Any process that activates or increases the frequency, rate or extent of protein ubiquitination involved in ubiquitin-dependent protein catabolic process.
2000061	regulation of ureter smooth muscle cell differentiation	P	Any process that modulates the frequency, rate or extent of ureter smooth muscle cell differentiation.
2000062	negative regulation of ureter smooth muscle cell differentiation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of ureter smooth muscle cell differentiation.
2000063	positive regulation of ureter smooth muscle cell differentiation	P	Any process that activates or increases the frequency, rate or extent of ureter smooth muscle cell differentiation.
2000064	regulation of cortisol biosynthetic process	P	Any process that modulates the frequency, rate or extent of cortisol biosynthetic process.
2000065	negative regulation of cortisol biosynthetic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of cortisol biosynthetic process.
2000066	positive regulation of cortisol biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of cortisol biosynthetic process.
2000067	regulation of root morphogenesis	P	Any process that modulates the frequency, rate or extent of root morphogenesis.
2000068	regulation of defense response to insect	P	Any process that modulates the frequency, rate or extent of defense response to insect.
2000069	regulation of post-embryonic root development	P	Any process that modulates the frequency, rate or extent of post-embryonic root development.
2000070	regulation of response to water deprivation	P	Any process that modulates the frequency, rate or extent of response to water deprivation.
2000071	regulation of defense response by callose deposition	P	Any process that modulates the frequency, rate or extent of defense response by callose deposition.
2000072	regulation of defense response to fungus, incompatible interaction	P	Any process that modulates the frequency, rate or extent of defense response to fungus, incompatible interaction.
2000073	regulation of cytokinesis, site selection	P	Any process that modulates the frequency, rate or extent of site selection that occurs as part of cytokinesis.
2000074	regulation of type B pancreatic cell development	P	Any process that modulates the frequency, rate or extent of pancreatic B cell development.
2000075	negative regulation of cytokinesis, site selection	P	Any process that stops, prevents, or reduces the frequency, rate or extent of site selection that occurs as part of cytokinesis.
2000076	positive regulation cytokinesis, site selection	P	Any process that activates or increases the frequency, rate or extent of site selection that occurs as part of cytokinesis.
2000077	negative regulation of type B pancreatic cell development	P	Any process that stops, prevents, or reduces the frequency, rate or extent of pancreatic B cell development.
2000078	positive regulation of type B pancreatic cell development	P	Any process that activates or increases the frequency, rate or extent of pancreatic B cell development.
2000079	regulation of canonical Wnt signaling pathway involved in controlling type B pancreatic cell proliferation	P	Any process that modulates the frequency, rate or extent of canonical Wnt signaling pathway modulating the rate or frequency of pancreatic B cell proliferation.
2000080	negative regulation of canonical Wnt signaling pathway involved in controlling type B pancreatic cell proliferation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of canonical Wnt signaling pathway modulating the rate or frequency of pancreatic B cell proliferation.
2000081	positive regulation of canonical Wnt signaling pathway involved in controlling type B pancreatic cell proliferation	P	Any process that activates or increases the frequency, rate or extent of canonical Wnt signaling pathway modulating the rate or frequency of pancreatic B cell proliferation.
2000082	regulation of L-ascorbic acid biosynthetic process	P	Any process that modulates the frequency, rate or extent of L-ascorbic acid biosynthetic process.
2000083	negative regulation of L-ascorbic acid biosynthetic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of L-ascorbic acid biosynthetic process.
2000084	regulation of mesenchymal to epithelial transition involved in mesonephros morphogenesis	P	Any process that modulates the frequency, rate or extent of mesenchymal to epithelial transition involved in mesonephros morphogenesis.
2000085	negative regulation of mesenchymal to epithelial transition involved in mesonephros morphogenesis	P	Any process that stops, prevents, or reduces the frequency, rate or extent of mesenchymal to epithelial transition involved in mesonephros morphogenesis.
2000086	positive regulation of mesenchymal to epithelial transition involved in mesonephros morphogenesis	P	Any process that activates or increases the frequency, rate or extent of mesenchymal to epithelial transition involved in mesonephros morphogenesis.
2000087	regulation of mesonephric glomerulus development	P	Any process that modulates the frequency, rate or extent of mesonephric glomerulus development.
2000088	negative regulation of mesonephric glomerulus development	P	Any process that stops, prevents, or reduces the frequency, rate or extent of mesonephric glomerulus development.
2000089	positive regulation of mesonephric glomerulus development	P	Any process that activates or increases the frequency, rate or extent of mesonephric glomerulus development.
2000090	regulation of mesonephric glomerular mesangial cell proliferation	P	Any process that modulates the frequency, rate or extent of mesonephric glomerular mesangial cell proliferation.
2000091	negative regulation of mesonephric glomerular mesangial cell proliferation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of mesonephric glomerular mesangial cell proliferation.
2000092	positive regulation of mesonephric glomerular mesangial cell proliferation	P	Any process that activates or increases the frequency, rate or extent of mesonephric glomerular mesangial cell proliferation.
2000093	regulation of mesonephric nephron tubule epithelial cell differentiation	P	Any process that modulates the frequency, rate or extent of mesonephric nephron tubule epithelial cell differentiation.
2000094	negative regulation of mesonephric nephron tubule epithelial cell differentiation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of mesonephric nephron tubule epithelial cell differentiation.
2000095	regulation of Wnt signaling pathway, planar cell polarity pathway	P	Any process that modulates the frequency, rate or extent of Wnt signaling pathway, planar cell polarity pathway.
2000096	positive regulation of Wnt signaling pathway, planar cell polarity pathway	P	Any process that activates or increases the frequency, rate or extent of Wnt signaling pathway, planar cell polarity pathway.
2000097	regulation of smooth muscle cell-matrix adhesion	P	Any process that modulates the frequency, rate or extent of smooth muscle cell-matrix adhesion.
2000098	negative regulation of smooth muscle cell-matrix adhesion	P	Any process that stops, prevents, or reduces the frequency, rate or extent of smooth muscle cell-matrix adhesion.
2000099	regulation of establishment or maintenance of bipolar cell polarity	P	Any process that modulates the frequency, rate or extent of establishment or maintenance of bipolar cell polarity.
2000100	regulation of establishment or maintenance of bipolar cell polarity regulating cell shape	P	Any process that modulates the frequency, rate or extent of establishment or maintenance of bipolar cell polarity regulating cell shape.
2000101	regulation of mammary stem cell proliferation	P	Any process that modulates the frequency, rate or extent of mammary stem cell proliferation.
2000102	negative regulation of mammary stem cell proliferation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of mammary stem cell proliferation.
2000103	positive regulation of mammary stem cell proliferation	P	Any process that activates or increases the frequency, rate or extent of mammary stem cell proliferation.
2000104	negative regulation of DNA-dependent DNA replication	P	Any process that stops, prevents, or reduces the frequency, rate or extent of DNA-dependent DNA replication.
2000105	positive regulation of DNA-dependent DNA replication	P	Any process that activates or increases the frequency, rate or extent of DNA-dependent DNA replication.
2000106	regulation of leukocyte apoptotic process	P	Any process that modulates the frequency, rate or extent of leukocyte apoptotic process.
2000107	negative regulation of leukocyte apoptotic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of leukocyte apoptotic process.
2000108	positive regulation of leukocyte apoptotic process	P	Any process that activates or increases the frequency, rate or extent of leukocyte apoptotic process.
2000109	regulation of macrophage apoptotic process	P	Any process that modulates the frequency, rate or extent of macrophage apoptotic process.
2000110	negative regulation of macrophage apoptotic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of macrophage apoptotic process.
2000111	positive regulation of macrophage apoptotic process	P	Any process that activates or increases the frequency, rate or extent of macrophage apoptotic process.
2000112	regulation of cellular macromolecule biosynthetic process	P	Any process that modulates the frequency, rate or extent of cellular macromolecule biosynthetic process.
2000113	negative regulation of cellular macromolecule biosynthetic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of cellular macromolecule biosynthetic process.
2000114	regulation of establishment of cell polarity	P	Any process that modulates the frequency, rate or extent of establishment of cell polarity.
2000115	regulation of maintenance of bipolar cell polarity regulating cell shape	P	Any process that modulates the frequency, rate or extent of maintenance of bipolar cell polarity regulating in cell shape.
2000116	regulation of cysteine-type endopeptidase activity	P	Any process that modulates the frequency, rate or extent of cysteine-type endopeptidase activity.
2000117	negative regulation of cysteine-type endopeptidase activity	P	Any process that stops, prevents, or reduces the frequency, rate or extent of cysteine-type endopeptidase activity.
2000118	regulation of sodium-dependent phosphate transport	P	Any process that modulates the frequency, rate or extent of sodium-dependent phosphate transport.
2000119	negative regulation of sodium-dependent phosphate transport	P	Any process that stops, prevents, or reduces the frequency, rate or extent of sodium-dependent phosphate transport.
2000120	positive regulation of sodium-dependent phosphate transport	P	Any process that activates or increases the frequency, rate or extent of sodium-dependent phosphate transport.
2000121	regulation of removal of superoxide radicals	P	Any process that modulates the frequency, rate or extent of removal of superoxide radicals.
2000122	negative regulation of stomatal complex development	P	Any process that stops, prevents, or reduces the frequency, rate or extent of stomatal complex development.
2000123	positive regulation of stomatal complex development	P	Any process that activates or increases the frequency, rate or extent of stomatal complex development.
2000124	regulation of endocannabinoid signaling pathway	P	Any process that modulates the frequency, rate or extent of endocannabinoid signaling pathway.
2000125	regulation of octopamine or tyramine signaling pathway	P	Any process that modulates the frequency, rate or extent of octopamine or tyramine signaling pathway.
2000126	negative regulation of octopamine or tyramine signaling pathway	P	Any process that stops, prevents, or reduces the frequency, rate or extent of octopamine or tyramine signaling pathway.
2000127	positive regulation of octopamine or tyramine signaling pathway	P	Any process that activates or increases the frequency, rate or extent of octopamine or tyramine signaling pathway.
2000128	regulation of octopamine signaling pathway	P	Any process that modulates the frequency, rate or extent of octopamine signaling pathway.
2000129	negative regulation of octopamine signaling pathway	P	Any process that stops, prevents, or reduces the frequency, rate or extent of octopamine signaling pathway.
2000130	positive regulation of octopamine signaling pathway	P	Any process that activates or increases the frequency, rate or extent of octopamine signaling pathway.
2000131	regulation of tyramine signaling pathway	P	Any process that modulates the frequency, rate or extent of tyramine signaling pathway.
2000132	negative regulation of tyramine signaling pathway	P	Any process that stops, prevents, or reduces the frequency, rate or extent of tyramine signaling pathway.
2000133	positive regulation of tyramine signaling pathway	P	Any process that activates or increases the frequency, rate or extent of tyramine signaling pathway.
2000134	negative regulation of G1/S transition of mitotic cell cycle	P	Any cell cycle regulatory process that prevents the commitment of a cell from G1 to S phase of the mitotic cell cycle.
2000136	regulation of cell proliferation involved in heart morphogenesis	P	Any process that modulates the frequency, rate or extent of cell proliferation involved in heart morphogenesis.
2000137	negative regulation of cell proliferation involved in heart morphogenesis	P	Any process that stops, prevents, or reduces the frequency, rate or extent of cell proliferation involved in heart morphogenesis.
2000138	positive regulation of cell proliferation involved in heart morphogenesis	P	Any process that activates or increases the frequency, rate or extent of cell proliferation involved in heart morphogenesis.
2000139	regulation of octopamine signaling pathway involved in response to food	P	Any process that modulates the frequency, rate or extent of octopamine signaling pathway involved in response to food.
2000140	negative regulation of octopamine signaling pathway involved in response to food	P	Any process that stops, prevents, or reduces the frequency, rate or extent of octopamine signaling pathway involved in response to food.
2000141	positive regulation of octopamine signaling pathway involved in response to food	P	Any process that activates or increases the frequency, rate or extent of octopamine signaling pathway involved in response to food.
2000142	regulation of DNA-templated transcription, initiation	P	Any process that modulates the frequency, rate or extent of DNA-templated transcription initiation.
2000143	negative regulation of DNA-templated transcription, initiation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of DNA-templated transcription initiation.
2000144	positive regulation of DNA-templated transcription, initiation	P	Any process that activates or increases the frequency, rate or extent of DNA-templated transcription initiation.
2000145	regulation of cell motility	P	Any process that modulates the frequency, rate or extent of cell motility.
2000146	negative regulation of cell motility	P	Any process that stops, prevents, or reduces the frequency, rate or extent of cell motility.
2000147	positive regulation of cell motility	P	Any process that activates or increases the frequency, rate or extent of cell motility.
2000148	regulation of planar cell polarity pathway involved in ventricular septum morphogenesis	P	Any process that modulates the frequency, rate or extent of planar cell polarity pathway involved in ventricular septum morphogenesis.
2000149	negative regulation of planar cell polarity pathway involved in ventricular septum morphogenesis	P	Any process that stops, prevents, or reduces the frequency, rate or extent of planar cell polarity pathway involved in ventricular septum morphogenesis.
2000150	regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis	P	Any process that modulates the frequency, rate or extent of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis.
2000151	negative regulation of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis	P	Any process that stops, prevents, or reduces the frequency, rate or extent of planar cell polarity pathway involved in cardiac muscle tissue morphogenesis.
2000152	regulation of ubiquitin-specific protease activity	P	Any process that modulates the frequency, rate or extent of regulation of ubiquitin-specific protease activity (deubiquitinase) activity.
2000155	positive regulation of cilium-dependent cell motility	P	Any process that activates or increases the frequency, rate or extent of cilium-dependent cell motility.
2000156	regulation of retrograde vesicle-mediated transport, Golgi to ER	P	Any process that modulates the frequency, rate or extent of retrograde vesicle-mediated transport, Golgi to ER.
2000157	negative regulation of ubiquitin-specific protease activity	P	Any process that stops, prevents, or reduces the frequency, rate or extent of ubiquitin-specific protease (deubiquitinase) activity.
2000158	positive regulation of ubiquitin-specific protease activity	P	Any process that activates or increases the frequency, rate or extent of ubiquitin-specific protease (deubiquitinase) activity.
2000159	regulation of planar cell polarity pathway involved in heart morphogenesis	P	Any process that modulates the frequency, rate or extent of planar cell polarity pathway involved in heart morphogenesis.
2000160	negative regulation of planar cell polarity pathway involved in heart morphogenesis	P	Any process that stops, prevents, or reduces the frequency, rate or extent of planar cell polarity pathway involved in heart morphogenesis.
2000161	regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis	P	Any process that modulates the frequency, rate or extent of planar cell polarity pathway involved in cardiac right atrium morphogenesis.
2000162	negative regulation of planar cell polarity pathway involved in cardiac right atrium morphogenesis	P	Any process that stops, prevents, or reduces the frequency, rate or extent of planar cell polarity pathway involved in cardiac right atrium morphogenesis.
2000163	regulation of planar cell polarity pathway involved in outflow tract morphogenesis	P	Any process that modulates the frequency, rate or extent of planar cell polarity pathway involved in outflow tract morphogenesis.
2000164	negative regulation of planar cell polarity pathway involved in outflow tract morphogenesis	P	Any process that stops, prevents, or reduces the frequency, rate or extent of planar cell polarity pathway involved in outflow tract morphogenesis.
2000165	regulation of planar cell polarity pathway involved in pericardium morphogenesis	P	Any process that modulates the frequency, rate or extent of planar cell polarity pathway involved in pericardium morphogenesis.
2000166	negative regulation of planar cell polarity pathway involved in pericardium morphogenesis	P	Any process that stops, prevents, or reduces the frequency, rate or extent of planar cell polarity pathway involved in pericardium morphogenesis.
2000167	regulation of planar cell polarity pathway involved in neural tube closure	P	Any process that modulates the frequency, rate or extent of planar cell polarity pathway involved in neural tube closure.
2000168	negative regulation of planar cell polarity pathway involved in neural tube closure	P	Any process that stops, prevents, or reduces the frequency, rate or extent of planar cell polarity pathway involved in neural tube closure.
2000169	regulation of peptidyl-cysteine S-nitrosylation	P	Any process that modulates the frequency, rate or extent of peptidyl-cysteine S-nitrosylation.
2000170	positive regulation of peptidyl-cysteine S-nitrosylation	P	Any process that activates or increases the frequency, rate or extent of peptidyl-cysteine S-nitrosylation.
2000171	negative regulation of dendrite development	P	Any process that stops, prevents, or reduces the frequency, rate or extent of dendrite development.
2000172	regulation of branching morphogenesis of a nerve	P	Any process that modulates the frequency, rate or extent of branching morphogenesis of a nerve.
2000173	negative regulation of branching morphogenesis of a nerve	P	Any process that stops, prevents, or reduces the frequency, rate or extent of branching morphogenesis of a nerve.
2000174	regulation of pro-T cell differentiation	P	Any process that modulates the frequency, rate or extent of pro-T cell differentiation.
2000175	negative regulation of pro-T cell differentiation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of pro-T cell differentiation.
2000176	positive regulation of pro-T cell differentiation	P	Any process that activates or increases the frequency, rate or extent of pro-T cell differentiation.
2000177	regulation of neural precursor cell proliferation	P	Any process that modulates the frequency, rate or extent of neural precursor cell proliferation.
2000178	negative regulation of neural precursor cell proliferation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of neural precursor cell proliferation.
2000179	positive regulation of neural precursor cell proliferation	P	Any process that activates or increases the frequency, rate or extent of neural precursor cell proliferation.
2000180	negative regulation of androgen biosynthetic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of androgen biosynthetic process.
2000181	negative regulation of blood vessel morphogenesis	P	Any process that stops, prevents, or reduces the frequency, rate or extent of blood vessel morphogenesis.
2000182	regulation of progesterone biosynthetic process	P	Any process that modulates the frequency, rate or extent of progesterone biosynthetic process.
2000183	negative regulation of progesterone biosynthetic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of progesterone biosynthetic process.
2000184	positive regulation of progesterone biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of progesterone biosynthetic process.
2000185	regulation of phosphate transmembrane transport	P	Any process that modulates the frequency, rate or extent of phosphate transmembrane transport.
2000186	negative regulation of phosphate transmembrane transport	P	Any process that stops, prevents, or reduces the frequency, rate or extent of phosphate transmembrane transport.
2000187	positive regulation of phosphate transmembrane transport	P	Any process that activates or increases the frequency, rate or extent of phosphate transmembrane transport.
2000188	regulation of cholesterol homeostasis	P	Any process that modulates the frequency, rate or extent of cholesterol homeostasis.
2000189	positive regulation of cholesterol homeostasis	P	Any process that activates or increases the frequency, rate or extent of cholesterol homeostasis.
2000191	regulation of fatty acid transport	P	Any process that modulates the frequency, rate or extent of fatty acid transport.
2000192	negative regulation of fatty acid transport	P	Any process that stops, prevents, or reduces the frequency, rate or extent of fatty acid transport.
2000193	positive regulation of fatty acid transport	P	Any process that activates or increases the frequency, rate or extent of fatty acid transport.
2000194	regulation of female gonad development	P	Any process that modulates the frequency, rate or extent of female gonad development.
2000195	negative regulation of female gonad development	P	Any process that stops, prevents, or reduces the frequency, rate or extent of female gonad development.
2000196	positive regulation of female gonad development	P	Any process that activates or increases the frequency, rate or extent of female gonad development.
2000197	regulation of ribonucleoprotein complex localization	P	Any process that modulates the frequency, rate or extent of ribonucleoprotein complex localization.
2000198	negative regulation of ribonucleoprotein complex localization	P	Any process that stops, prevents, or reduces the frequency, rate or extent of ribonucleoprotein complex localization.
2000199	positive regulation of ribonucleoprotein complex localization	P	Any process that activates or increases the frequency, rate or extent of ribonucleoprotein complex localization.
2000200	regulation of ribosomal subunit export from nucleus	P	Any process that modulates the frequency, rate or extent of ribosomal subunit export from nucleus.
2000201	negative regulation of ribosomal subunit export from nucleus	P	Any process that stops, prevents, or reduces the frequency, rate or extent of ribosomal subunit export from nucleus.
2000202	positive regulation of ribosomal subunit export from nucleus	P	Any process that activates or increases the frequency, rate or extent of ribosomal subunit export from nucleus.
2000203	regulation of ribosomal large subunit export from nucleus	P	Any process that modulates the frequency, rate or extent of ribosomal large subunit export from nucleus.
2000204	negative regulation of ribosomal large subunit export from nucleus	P	Any process that stops, prevents, or reduces the frequency, rate or extent of ribosomal large subunit export from nucleus.
2000205	positive regulation of ribosomal large subunit export from nucleus	P	Any process that activates or increases the frequency, rate or extent of ribosomal large subunit export from nucleus.
2000206	regulation of ribosomal small subunit export from nucleus	P	Any process that modulates the frequency, rate or extent of ribosomal small subunit export from nucleus.
2000207	negative regulation of ribosomal small subunit export from nucleus	P	Any process that stops, prevents, or reduces the frequency, rate or extent of ribosomal small subunit export from nucleus.
2000208	positive regulation of ribosomal small subunit export from nucleus	P	Any process that activates or increases the frequency, rate or extent of ribosomal small subunit export from nucleus.
2000209	regulation of anoikis	P	Any process that modulates the frequency, rate or extent of anoikis.
2000210	positive regulation of anoikis	P	Any process that activates or increases the frequency, rate or extent of anoikis.
2000211	regulation of glutamate metabolic process	P	Any process that modulates the frequency, rate or extent of glutamate metabolic process.
2000212	negative regulation of glutamate metabolic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of glutamate metabolic process.
2000213	positive regulation of glutamate metabolic process	P	Any process that activates or increases the frequency, rate or extent of glutamate metabolic process.
2000214	regulation of proline metabolic process	P	Any process that modulates the frequency, rate or extent of proline metabolic process.
2000215	negative regulation of proline metabolic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of proline metabolic process.
2000216	positive regulation of proline metabolic process	P	Any process that activates or increases the frequency, rate or extent of proline metabolic process.
2000217	regulation of invasive growth in response to glucose limitation	P	Any process that modulates the frequency, rate or extent of invasive growth in response to glucose limitation.
2000218	negative regulation of invasive growth in response to glucose limitation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of invasive growth in response to glucose limitation.
2000219	positive regulation of invasive growth in response to glucose limitation	P	Any process that activates or increases the frequency, rate or extent of invasive growth in response to glucose limitation.
2000220	regulation of pseudohyphal growth	P	Any process that modulates the frequency, rate or extent of pseudohyphal growth.
2000221	negative regulation of pseudohyphal growth	P	Any process that stops, prevents, or reduces the frequency, rate or extent of pseudohyphal growth.
2000222	positive regulation of pseudohyphal growth	P	Any process that activates or increases the frequency, rate or extent of pseudohyphal growth.
2000223	regulation of BMP signaling pathway involved in heart jogging	P	Any process that modulates the frequency, rate or extent of BMP signaling pathway involved in heart jogging.
2000224	regulation of testosterone biosynthetic process	P	Any process that modulates the frequency, rate or extent of testosterone biosynthetic process.
2000225	negative regulation of testosterone biosynthetic process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of testosterone biosynthetic process.
2000226	regulation of pancreatic A cell differentiation	P	Any process that modulates the frequency, rate or extent of pancreatic A cell differentiation.
2000227	negative regulation of pancreatic A cell differentiation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of pancreatic A cell differentiation.
2000228	positive regulation of pancreatic A cell differentiation	P	Any process that activates or increases the frequency, rate or extent of pancreatic A cell differentiation.
2000229	regulation of pancreatic stellate cell proliferation	P	Any process that modulates the frequency, rate or extent of pancreatic stellate cell proliferation.
2000230	negative regulation of pancreatic stellate cell proliferation	P	Any process that stops, prevents, or reduces the frequency, rate or extent of pancreatic stellate cell proliferation.
2000231	positive regulation of pancreatic stellate cell proliferation	P	Any process that activates or increases the frequency, rate or extent of pancreatic stellate cell proliferation.
2000232	regulation of rRNA processing	P	Any process that modulates the frequency, rate or extent of rRNA processing.
2000233	negative regulation of rRNA processing	P	Any process that stops, prevents, or reduces the frequency, rate or extent of rRNA processing.
2000234	positive regulation of rRNA processing	P	Any process that activates or increases the frequency, rate or extent of rRNA processing.
2000235	regulation of tRNA processing	P	Any process that modulates the frequency, rate or extent of tRNA processing.
2000236	negative regulation of tRNA processing	P	Any process that stops, prevents, or reduces the frequency, rate or extent of tRNA processing.
2000237	positive regulation of tRNA processing	P	Any process that activates or increases the frequency, rate or extent of tRNA processing.
2000238	regulation of tRNA export from nucleus	P	Any process that modulates the frequency, rate or extent of tRNA export from nucleus.
2000239	negative regulation of tRNA export from nucleus	P	Any process that stops, prevents, or reduces the frequency, rate or extent of tRNA export from nucleus.
2000240	positive regulation of tRNA export from nucleus	P	Any process that activates or increases the frequency, rate or extent of tRNA export from nucleus.
2000241	regulation of reproductive process	P	Any process that modulates the frequency, rate or extent of reproductive process.
2000242	negative regulation of reproductive process	P	Any process that stops, prevents, or reduces the frequency, rate or extent of reproductive process.
2000243	positive regulation of reproductive process	P	Any process that activates or increases the frequency, rate or extent of reproductive process.
2000244	regulation of FtsZ-dependent cytokinesis	P	Any process that modulates the frequency, rate or extent of FtsZ-dependent cytokinesis.
2000245	negative regulation of FtsZ-dependent cytokinesis	P	Any process that stops, prevents, or reduces the frequency, rate or extent of Ftsz-dependent cytokinesis.
2000246	positive regulation of FtsZ-dependent cytokinesis	P	Any process that activates or increases the frequency, rate or extent of Ftsz-dependent cytokinesis.
2000247	positive regulation of establishment or maintenance of bipolar cell polarity regulating cell shape	P	Any process that activates or increases the frequency, rate or extent of establishment or maintenance of bipolar cell polarity regulating cell shape.
2000248	negative regulation of establishment or maintenance of neuroblast polarity	P	Any process that stops, prevents, or reduces the frequency, rate or extent of establishment or maintenance of neuroblast polarity.
2000249	regulation of actin cytoskeleton reorganization	P	Any process that modulates the frequency, rate or extent of actin cytoskeleton reorganization.
2000250	negative regulation of actin cytoskeleton reorganization	P	Any process that stops, prevents, or reduces the frequency, rate or extent of actin cytoskeleton reorganization.
2000251	positive regulation of actin cytoskeleton reorganization	P	Any process that activates or increases the frequency, rate or extent of actin cytoskeleton reorganization.
2000252	negative regulation of feeding behavior	P	Any process that stops, prevents or reduces the frequency, rate or extent of feeding behavior.
2000253	positive regulation of feeding behavior	P	Any process that activates or increases the frequency, rate or extent of feeding behavior.
2000254	regulation of male germ cell proliferation	P	Any process that modulates the frequency, rate or extent of male germ cell proliferation.
2000255	negative regulation of male germ cell proliferation	P	Any process that stops, prevents or reduces the frequency, rate or extent of male germ cell proliferation.
2000256	positive regulation of male germ cell proliferation	P	Any process that activates or increases the frequency, rate or extent of male germ cell proliferation.
2000257	regulation of protein activation cascade	P	Any process that modulates the frequency, rate or extent of protein activation cascade.
2000258	negative regulation of protein activation cascade	P	Any process that stops, prevents or reduces the frequency, rate or extent of protein activation cascade.
2000259	positive regulation of protein activation cascade	P	Any process that activates or increases the frequency, rate or extent of protein activation cascade.
2000260	regulation of blood coagulation, common pathway	P	Any process that modulates the frequency, rate or extent of blood coagulation, common pathway.
2000261	negative regulation of blood coagulation, common pathway	P	Any process that stops, prevents or reduces the frequency, rate or extent of blood coagulation, common pathway.
2000262	positive regulation of blood coagulation, common pathway	P	Any process that activates or increases the frequency, rate or extent of blood coagulation, common pathway.
2000263	regulation of blood coagulation, extrinsic pathway	P	Any process that modulates the frequency, rate or extent of blood coagulation, extrinsic pathway.
2000264	negative regulation of blood coagulation, extrinsic pathway	P	Any process that stops, prevents or reduces the frequency, rate or extent of blood coagulation, extrinsic pathway.
2000265	positive regulation of blood coagulation, extrinsic pathway	P	Any process that activates or increases the frequency, rate or extent of blood coagulation, extrinsic pathway.
2000266	regulation of blood coagulation, intrinsic pathway	P	Any process that modulates the frequency, rate or extent of blood coagulation, intrinsic pathway.
2000267	negative regulation of blood coagulation, intrinsic pathway	P	Any process that stops, prevents or reduces the frequency, rate or extent of blood coagulation, intrinsic pathway.
2000268	positive regulation of blood coagulation, intrinsic pathway	P	Any process that activates or increases the frequency, rate or extent of blood coagulation, intrinsic pathway.
2000269	regulation of fibroblast apoptotic process	P	Any process that modulates the frequency, rate or extent of fibroblast apoptotic process.
2000270	negative regulation of fibroblast apoptotic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of fibroblast apoptotic process.
2000271	positive regulation of fibroblast apoptotic process	P	Any process that activates or increases the frequency, rate or extent of fibroblast apoptotic process.
2000272	negative regulation of receptor activity	P	Any process that stops, prevents or reduces the frequency, rate or extent of receptor activity.
2000273	positive regulation of receptor activity	P	Any process that activates or increases the frequency, rate or extent of receptor activity.
2000274	regulation of epithelial cell migration, open tracheal system	P	Any process that modulates the frequency, rate or extent of epithelial cell migration, open tracheal system.
2000275	regulation of oxidative phosphorylation uncoupler activity	P	Any process that modulates the frequency, rate or extent of oxidative phosphorylation uncoupler activity.
2000276	negative regulation of oxidative phosphorylation uncoupler activity	P	Any process that stops, prevents or reduces the frequency, rate or extent of oxidative phosphorylation uncoupler activity.
2000277	positive regulation of oxidative phosphorylation uncoupler activity	P	Any process that activates or increases the frequency, rate or extent of oxidative phosphorylation uncoupler activity.
2000278	regulation of DNA biosynthetic process	P	Any process that modulates the frequency, rate or extent of DNA biosynthetic process.
2000279	negative regulation of DNA biosynthetic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of DNA biosynthetic process.
2000280	regulation of root development	P	Any process that modulates the frequency, rate or extent of root development.
2000281	regulation of histone H3-T3 phosphorylation	P	Any process that modulates the frequency, rate or extent of histone H3-T3 phosphorylation.
2000282	regulation of cellular amino acid biosynthetic process	P	Any process that modulates the frequency, rate or extent of cellular amino acid biosynthetic process.
2000283	negative regulation of cellular amino acid biosynthetic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of cellular amino acid biosynthetic process.
2000284	positive regulation of cellular amino acid biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of cellular amino acid biosynthetic process.
2000286	receptor internalization involved in canonical Wnt signaling pathway	P	A receptor internalization process that contributes to canonical Wnt signaling pathway.
2000287	positive regulation of myotome development	P	Any process that activates or increases the frequency, rate or extent of myotome development.
2000288	positive regulation of myoblast proliferation	P	Any process that activates or increases the frequency, rate or extent of myoblast proliferation.
2000289	regulation of photoreceptor cell axon guidance	P	Any process that modulates the frequency, rate or extent of photoreceptor cell axon guidance.
2000290	regulation of myotome development	P	Any process that modulates the frequency, rate or extent of myotome development.
2000291	regulation of myoblast proliferation	P	Any process that modulates the frequency, rate or extent of myoblast proliferation.
2000292	regulation of defecation	P	Any process that modulates the frequency, rate or extent of defecation.
2000293	negative regulation of defecation	P	Any process that stops, prevents or reduces the frequency, rate or extent of defecation.
2000294	positive regulation of defecation	P	Any process that activates or increases the frequency, rate or extent of defecation.
2000295	regulation of hydrogen peroxide catabolic process	P	Any process that modulates the frequency, rate or extent of hydrogen peroxide catabolic process.
2000296	negative regulation of hydrogen peroxide catabolic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of hydrogen peroxide catabolic process.
2000297	negative regulation of synapse maturation	P	Any process that stops, prevents or reduces the frequency, rate or extent of synapse maturation.
2000298	regulation of Rho-dependent protein serine/threonine kinase activity	P	Any process that modulates the frequency, rate or extent of Rho-dependent protein serine/threonine kinase activity.
2000299	negative regulation of Rho-dependent protein serine/threonine kinase activity	P	Any process that stops, prevents or reduces the frequency, rate or extent of Rho-dependent protein serine/threonine kinase activity.
2000300	regulation of synaptic vesicle exocytosis	P	Any process that modulates the frequency, rate or extent of synaptic vesicle exocytosis.
2000301	negative regulation of synaptic vesicle exocytosis	P	Any process that stops, prevents or reduces the frequency, rate or extent of synaptic vesicle exocytosis.
2000302	positive regulation of synaptic vesicle exocytosis	P	Any process that activates or increases the frequency, rate or extent of synaptic vesicle exocytosis.
2000303	regulation of ceramide biosynthetic process	P	Any process that modulates the frequency, rate or extent of a ceramide biosynthetic process.
2000304	positive regulation of ceramide biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of ceramide biosynthetic process.
2000305	semaphorin-plexin signaling pathway involved in regulation of photoreceptor cell axon guidance	P	Any semaphorin-plexin signaling pathway that is involved in regulation of photoreceptor cell axon guidance.
2000306	positive regulation of photomorphogenesis	P	Any process that activates or increases the frequency, rate or extent of photomorphogenesis.
2000307	regulation of tumor necrosis factor (ligand) superfamily member 11 production	P	Any process that modulates the frequency, rate or extent of tumor necrosis factor (ligand) superfamily member 11 production.
2000308	negative regulation of tumor necrosis factor (ligand) superfamily member 11 production	P	Any process that stops, prevents or reduces the frequency, rate or extent of tumor necrosis factor (ligand) superfamily member 11 production.
2000309	positive regulation of tumor necrosis factor (ligand) superfamily member 11 production	P	Any process that activates or increases the frequency, rate or extent of tumor necrosis factor (ligand) superfamily member 11 production.
2000310	regulation of N-methyl-D-aspartate selective glutamate receptor activity	P	Any process that modulates the frequency, rate or extent of N-methyl-D-aspartate selective glutamate receptor activity.
2000311	regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity	P	Any process that modulates the frequency, rate or extent of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity.
2000312	regulation of kainate selective glutamate receptor activity	P	Any process that modulates the frequency, rate or extent of kainate selective glutamate receptor activity.
2000313	regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation	P	Any process that modulates the frequency, rate or extent of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation.
2000314	negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation	P	Any process that stops, prevents or reduces the frequency, rate or extent of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation.
2000315	positive regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation	P	Any process that activates or increases the frequency, rate or extent of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation.
2000316	regulation of T-helper 17 type immune response	P	Any process that modulates the frequency, rate or extent of T-helper 17 type immune response.
2000317	negative regulation of T-helper 17 type immune response	P	Any process that stops, prevents or reduces the frequency, rate or extent of T-helper 17 type immune response.
2000318	positive regulation of T-helper 17 type immune response	P	Any process that activates or increases the frequency, rate or extent of T-helper 17 type immune response.
2000319	regulation of T-helper 17 cell differentiation	P	Any process that modulates the frequency, rate or extent of T-helper 17 cell differentiation.
2000320	negative regulation of T-helper 17 cell differentiation	P	Any process that stops, prevents or reduces the frequency, rate or extent of T-helper 17 cell differentiation.
2000321	positive regulation of T-helper 17 cell differentiation	P	Any process that activates or increases the frequency, rate or extent of T-helper 17 cell differentiation.
2000322	regulation of glucocorticoid receptor signaling pathway	P	Any process that modulates the frequency, rate or extent of glucocorticoid receptor signaling pathway.
2000323	negative regulation of glucocorticoid receptor signaling pathway	P	Any process that stops, prevents or reduces the frequency, rate or extent of glucocorticoid receptor signaling pathway.
2000324	positive regulation of glucocorticoid receptor signaling pathway	P	Any process that activates or increases the frequency, rate or extent of glucocorticoid receptor signaling pathway.
2000325	regulation of ligand-dependent nuclear receptor transcription coactivator activity	P	Any process that modulates the frequency, rate or extent of ligand-dependent nuclear receptor transcription coactivator activity.
2000326	negative regulation of ligand-dependent nuclear receptor transcription coactivator activity	P	Any process that stops, prevents or reduces the frequency, rate or extent of ligand-dependent nuclear receptor transcription coactivator activity.
2000327	positive regulation of ligand-dependent nuclear receptor transcription coactivator activity	P	Any process that activates or increases the frequency, rate or extent of ligand-dependent nuclear receptor transcription coactivator activity.
2000328	regulation of T-helper 17 cell lineage commitment	P	Any process that modulates the frequency, rate or extent of T-helper 17 cell lineage commitment.
2000329	negative regulation of T-helper 17 cell lineage commitment	P	Any process that stops, prevents or reduces the frequency, rate or extent of T-helper 17 cell lineage commitment.
2000330	positive regulation of T-helper 17 cell lineage commitment	P	Any process that activates or increases the frequency, rate or extent of T-helper 17 cell lineage commitment.
2000331	regulation of terminal button organization	P	Any process that modulates the frequency, rate or extent of terminal button organization.
2000332	regulation of blood microparticle formation	P	Any process that modulates the frequency, rate or extent of blood microparticle formation.
2000333	negative regulation of blood microparticle formation	P	Any process that stops, prevents or reduces the frequency, rate or extent of blood microparticle formation.
2000334	positive regulation of blood microparticle formation	P	Any process that activates or increases the frequency, rate or extent of blood microparticle formation.
2000335	regulation of endothelial microparticle formation	P	Any process that modulates the frequency, rate or extent of endothelial microparticle formation.
2000336	negative regulation of endothelial microparticle formation	P	Any process that stops, prevents or reduces the frequency, rate or extent of endothelial microparticle formation.
2000337	positive regulation of endothelial microparticle formation	P	Any process that activates or increases the frequency, rate or extent of endothelial microparticle formation.
2000338	regulation of chemokine (C-X-C motif) ligand 1 production	P	Any process that modulates the frequency, rate or extent of chemokine (C-X-C motif) ligand 1 production.
2000339	negative regulation of chemokine (C-X-C motif) ligand 1 production	P	Any process that stops, prevents or reduces the frequency, rate or extent of chemokine (C-X-C motif) ligand 1 production.
2000340	positive regulation of chemokine (C-X-C motif) ligand 1 production	P	Any process that activates or increases the frequency, rate or extent of chemokine (C-X-C motif) ligand 1 production.
2000341	regulation of chemokine (C-X-C motif) ligand 2 production	P	Any process that modulates the frequency, rate or extent of chemokine (C-X-C motif) ligand 2 production.
2000342	negative regulation of chemokine (C-X-C motif) ligand 2 production	P	Any process that stops, prevents or reduces the frequency, rate or extent of chemokine (C-X-C motif) ligand 2 production.
2000343	positive regulation of chemokine (C-X-C motif) ligand 2 production	P	Any process that activates or increases the frequency, rate or extent of chemokine (C-X-C motif) ligand 2 production.
2000344	positive regulation of acrosome reaction	P	Any process that activates or increases the frequency, rate or extent of the acrosome reaction.
2000345	regulation of hepatocyte proliferation	P	Any process that modulates the frequency, rate or extent of hepatocyte proliferation.
2000346	negative regulation of hepatocyte proliferation	P	Any process that stops, prevents or reduces the frequency, rate or extent of hepatocyte proliferation.
2000347	positive regulation of hepatocyte proliferation	P	Any process that activates or increases the frequency, rate or extent of hepatocyte proliferation.
2000348	regulation of CD40 signaling pathway	P	Any process that modulates the frequency, rate or extent of signaling via the CD40 signaling pathway.
2000349	negative regulation of CD40 signaling pathway	P	Any process that stops, prevents or reduces the frequency, rate or extent of signaling via the CD40 signaling pathway.
2000350	positive regulation of CD40 signaling pathway	P	Any process that activates or increases the frequency, rate or extent of signaling via the CD40 signaling pathway.
2000351	regulation of endothelial cell apoptotic process	P	Any process that modulates the frequency, rate or extent of endothelial cell apoptotic process.
2000352	negative regulation of endothelial cell apoptotic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of endothelial cell apoptotic process.
2000353	positive regulation of endothelial cell apoptotic process	P	Any process that activates or increases the frequency, rate or extent of endothelial cell apoptotic process.
2000354	regulation of ovarian follicle development	P	Any process that modulates the frequency, rate or extent of ovarian follicle development.
2000355	negative regulation of ovarian follicle development	P	Any process that stops, prevents or reduces the frequency, rate or extent of ovarian follicle development.
2000356	regulation of kidney smooth muscle cell differentiation	P	Any process that modulates the frequency, rate or extent of kidney smooth muscle cell differentiation.
2000357	negative regulation of kidney smooth muscle cell differentiation	P	Any process that stops, prevents or reduces the frequency, rate or extent of kidney smooth muscle cell differentiation.
2000358	positive regulation of kidney smooth muscle cell differentiation	P	Any process that activates or increases the frequency, rate or extent of kidney smooth muscle cell differentiation.
2000359	regulation of binding of sperm to zona pellucida	P	Any process that modulates the frequency, rate or extent of binding of sperm to the zona pellucida.
2000360	negative regulation of binding of sperm to zona pellucida	P	Any process that stops, prevents or reduces the frequency, rate or extent of binding of sperm to the zona pellucida.
2000361	regulation of prostaglandin-E synthase activity	P	Any process that modulates the frequency, rate or extent of prostaglandin-E synthase activity.
2000362	negative regulation of prostaglandin-E synthase activity	P	Any process that stops, prevents or reduces the frequency, rate or extent of prostaglandin-E synthase activity.
2000363	positive regulation of prostaglandin-E synthase activity	P	Any process that activates or increases the frequency, rate or extent of prostaglandin-E synthase activity.
2000364	regulation of STAT protein import into nucleus	P	Any process that modulates the frequency, rate or extent of STAT protein import into nucleus.
2000365	negative regulation of STAT protein import into nucleus	P	Any process that stops, prevents or reduces the frequency, rate or extent of STAT protein import into nucleus.
2000366	positive regulation of STAT protein import into nucleus	P	Any process that activates or increases the frequency, rate or extent of STAT protein import into nucleus.
2000367	regulation of acrosomal vesicle exocytosis	P	Any process that modulates the frequency, rate or extent of acrosomal vesicle exocytosis.
2000368	positive regulation of acrosomal vesicle exocytosis	P	Any process that activates or increases the frequency, rate or extent of acrosomal vesicle exocytosis.
2000369	regulation of clathrin-dependent endocytosis	P	Any process that modulates the frequency, rate or extent of clathrin-mediated endocytosis.
2000370	positive regulation of clathrin-dependent endocytosis	P	Any process that activates or increases the frequency, rate or extent of clathrin-mediated endocytosis.
2000371	regulation of DNA topoisomerase (ATP-hydrolyzing) activity	P	Any process that modulates the frequency, rate or extent of DNA topoisomerase (ATP-hydrolyzing) activity.
2000372	negative regulation of DNA topoisomerase (ATP-hydrolyzing) activity	P	Any process that stops, prevents or reduces the frequency, rate or extent of DNA topoisomerase (ATP-hydrolyzing) activity.
2000373	positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity	P	Any process that activates or increases the frequency, rate or extent of DNA topoisomerase (ATP-hydrolyzing) activity.
2000374	regulation of oxygen metabolic process	P	Any process that modulates the frequency, rate or extent of oxygen metabolic process.
2000375	negative regulation of oxygen metabolic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of oxygen metabolic process.
2000376	positive regulation of oxygen metabolic process	P	Any process that activates or increases the frequency, rate or extent of oxygen metabolic process.
2000377	regulation of reactive oxygen species metabolic process	P	Any process that modulates the frequency, rate or extent of reactive oxygen species metabolic process.
2000378	negative regulation of reactive oxygen species metabolic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of reactive oxygen species metabolic process.
2000379	positive regulation of reactive oxygen species metabolic process	P	Any process that activates or increases the frequency, rate or extent of reactive oxygen species metabolic process.
2000380	regulation of mesoderm development	P	Any process that modulates the frequency, rate or extent of mesoderm development.
2000381	negative regulation of mesoderm development	P	Any process that stops, prevents or reduces the frequency, rate or extent of mesoderm development.
2000382	positive regulation of mesoderm development	P	Any process that activates or increases the frequency, rate or extent of mesoderm development.
2000383	regulation of ectoderm development	P	Any process that modulates the frequency, rate or extent of ectoderm development.
2000384	negative regulation of ectoderm development	P	Any process that stops, prevents or reduces the frequency, rate or extent of ectoderm development.
2000385	positive regulation of ectoderm development	P	Any process that activates or increases the frequency, rate or extent of ectoderm development.
2000386	positive regulation of ovarian follicle development	P	Any process that activates or increases the frequency, rate or extent of ovarian follicle development.
2000387	regulation of antral ovarian follicle growth	P	Any process that modulates the frequency, rate or extent of antral ovarian follicle growth.
2000388	positive regulation of antral ovarian follicle growth	P	Any process that activates or increases the frequency, rate or extent of antral ovarian follicle growth.
2000389	regulation of neutrophil extravasation	P	Any process that modulates the frequency, rate or extent of neutrophil extravasation.
2000390	negative regulation of neutrophil extravasation	P	Any process that stops, prevents or reduces the frequency, rate or extent of neutrophil extravasation.
2000391	positive regulation of neutrophil extravasation	P	Any process that activates or increases the frequency, rate or extent of neutrophil extravasation.
2000392	regulation of lamellipodium morphogenesis	P	Any process that modulates the frequency, rate or extent of lamellipodium morphogenesis.
2000393	negative regulation of lamellipodium morphogenesis	P	Any process that stops, prevents or reduces the frequency, rate or extent of lamellipodium morphogenesis.
2000394	positive regulation of lamellipodium morphogenesis	P	Any process that activates or increases the frequency, rate or extent of lamellipodium morphogenesis.
2000395	regulation of ubiquitin-dependent endocytosis	P	Any process that modulates the frequency, rate or extent of ubiquitin-dependent endocytosis.
2000396	negative regulation of ubiquitin-dependent endocytosis	P	Any process that stops, prevents or reduces the frequency, rate or extent of ubiquitin-dependent endocytosis.
2000397	positive regulation of ubiquitin-dependent endocytosis	P	Any process that activates or increases the frequency, rate or extent of ubiquitin-dependent endocytosis.
2000398	regulation of thymocyte aggregation	P	Any process that modulates the frequency, rate or extent of thymocyte aggregation.
2000399	negative regulation of thymocyte aggregation	P	Any process that stops, prevents or reduces the frequency, rate or extent of thymocyte aggregation.
2000400	positive regulation of thymocyte aggregation	P	Any process that activates or increases the frequency, rate or extent of thymocyte aggregation.
2000401	regulation of lymphocyte migration	P	Any process that modulates the frequency, rate or extent of lymphocyte migration.
2000402	negative regulation of lymphocyte migration	P	Any process that stops, prevents or reduces the frequency, rate or extent of lymphocyte migration.
2000403	positive regulation of lymphocyte migration	P	Any process that activates or increases the frequency, rate or extent of lymphocyte migration.
2000404	regulation of T cell migration	P	Any process that modulates the frequency, rate or extent of T cell migration.
2000405	negative regulation of T cell migration	P	Any process that stops, prevents or reduces the frequency, rate or extent of T cell migration.
2000406	positive regulation of T cell migration	P	Any process that activates or increases the frequency, rate or extent of T cell migration.
2000407	regulation of T cell extravasation	P	Any process that modulates the frequency, rate or extent of T cell extravasation.
2000408	negative regulation of T cell extravasation	P	Any process that stops, prevents or reduces the frequency, rate or extent of T cell extravasation.
2000409	positive regulation of T cell extravasation	P	Any process that activates or increases the frequency, rate or extent of T cell extravasation.
2000410	regulation of thymocyte migration	P	Any process that modulates the frequency, rate or extent of thymocyte migration.
2000411	negative regulation of thymocyte migration	P	Any process that stops, prevents or reduces the frequency, rate or extent of thymocyte migration.
2000412	positive regulation of thymocyte migration	P	Any process that activates or increases the frequency, rate or extent of thymocyte migration.
2000413	regulation of fibronectin-dependent thymocyte migration	P	Any process that modulates the frequency, rate or extent of fibronectin-dependent thymocyte migration.
2000414	negative regulation of fibronectin-dependent thymocyte migration	P	Any process that stops, prevents or reduces the frequency, rate or extent of fibronectin-dependent thymocyte migration.
2000415	positive regulation of fibronectin-dependent thymocyte migration	P	Any process that activates or increases the frequency, rate or extent of fibronectin-dependent thymocyte migration.
2000416	regulation of eosinophil migration	P	Any process that modulates the frequency, rate or extent of eosinophil migration.
2000417	negative regulation of eosinophil migration	P	Any process that stops, prevents or reduces the frequency, rate or extent of eosinophil migration.
2000418	positive regulation of eosinophil migration	P	Any process that activates or increases the frequency, rate or extent of eosinophil migration.
2000419	regulation of eosinophil extravasation	P	Any process that modulates the frequency, rate or extent of eosinophil extravasation.
2000420	negative regulation of eosinophil extravasation	P	Any process that stops, prevents or reduces the frequency, rate or extent of eosinophil extravasation.
2000421	positive regulation of eosinophil extravasation	P	Any process that activates or increases the frequency, rate or extent of eosinophil extravasation.
2000422	regulation of eosinophil chemotaxis	P	Any process that modulates the frequency, rate or extent of eosinophil chemotaxis.
2000423	negative regulation of eosinophil chemotaxis	P	Any process that stops, prevents or reduces the frequency, rate or extent of eosinophil chemotaxis.
2000424	positive regulation of eosinophil chemotaxis	P	Any process that activates or increases the frequency, rate or extent of eosinophil chemotaxis.
2000425	regulation of apoptotic cell clearance	P	Any process that modulates the frequency, rate or extent of apoptotic cell clearance.
2000426	negative regulation of apoptotic cell clearance	P	Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic cell clearance.
2000427	positive regulation of apoptotic cell clearance	P	Any process that activates or increases the frequency, rate or extent of apoptotic cell clearance.
2000428	regulation of neutrophil aggregation	P	Any process that modulates the frequency, rate or extent of neutrophil aggregation.
2000429	negative regulation of neutrophil aggregation	P	Any process that stops, prevents or reduces the frequency, rate or extent of neutrophil aggregation.
2000430	positive regulation of neutrophil aggregation	P	Any process that activates or increases the frequency, rate or extent of neutrophil aggregation.
2000431	regulation of cytokinesis, actomyosin contractile ring assembly	P	Any process that modulates the frequency, rate or extent of cytokinesis, actomyosin contractile ring assembly.
2000432	negative regulation of cytokinesis, actomyosin contractile ring assembly	P	Any process that stops, prevents or reduces the frequency, rate or extent of cytokinesis, actomyosin contractile ring assembly.
2000433	positive regulation of cytokinesis, actomyosin contractile ring assembly	P	Any process that activates or increases the frequency, rate or extent of cytokinesis, actomyosin contractile ring assembly.
2000434	regulation of protein neddylation	P	Any process that modulates the frequency, rate or extent of protein neddylation.
2000435	negative regulation of protein neddylation	P	Any process that stops, prevents or reduces the frequency, rate or extent of protein neddylation.
2000436	positive regulation of protein neddylation	P	Any process that activates or increases the frequency, rate or extent of protein neddylation.
2000437	regulation of monocyte extravasation	P	Any process that modulates the frequency, rate or extent of monocyte extravasation.
2000438	negative regulation of monocyte extravasation	P	Any process that stops, prevents or reduces the frequency, rate or extent of monocyte extravasation.
2000439	positive regulation of monocyte extravasation	P	Any process that activates or increases the frequency, rate or extent of monocyte extravasation.
2000440	regulation of toll-like receptor 15 signaling pathway	P	Any process that modulates the frequency, rate or extent of toll-like receptor 15 signaling pathway.
2000441	negative regulation of toll-like receptor 15 signaling pathway	P	Any process that stops, prevents or reduces the frequency, rate or extent of toll-like receptor 15 signaling pathway.
2000442	positive regulation of toll-like receptor 15 signaling pathway	P	Any process that activates or increases the frequency, rate or extent of toll-like receptor 15 signaling pathway.
2000443	regulation of toll-like receptor 21 signaling pathway	P	Any process that modulates the frequency, rate or extent of toll-like receptor 21 signaling pathway.
2000444	negative regulation of toll-like receptor 21 signaling pathway	P	Any process that stops, prevents or reduces the frequency, rate or extent of toll-like receptor 21 signaling pathway.
2000445	positive regulation of toll-like receptor 21 signaling pathway	P	Any process that activates or increases the frequency, rate or extent of toll-like receptor 21 signaling pathway.
2000446	regulation of macrophage migration inhibitory factor signaling pathway	P	Any process that modulates the frequency, rate or extent of macrophage migration inhibitory factor signaling pathway.
2000447	negative regulation of macrophage migration inhibitory factor signaling pathway	P	Any process that stops, prevents or reduces the frequency, rate or extent of macrophage migration inhibitory factor signaling pathway.
2000448	positive regulation of macrophage migration inhibitory factor signaling pathway	P	Any process that activates or increases the frequency, rate or extent of macrophage migration inhibitory factor signaling pathway.
2000449	regulation of CD8-positive, alpha-beta T cell extravasation	P	Any process that modulates the frequency, rate or extent of CD8-positive, alpha-beta T cell extravasation.
2000450	negative regulation of CD8-positive, alpha-beta T cell extravasation	P	Any process that stops, prevents or reduces the frequency, rate or extent of CD8-positive, alpha-beta T cell extravasation.
2000451	positive regulation of CD8-positive, alpha-beta T cell extravasation	P	Any process that activates or increases the frequency, rate or extent of CD8-positive, alpha-beta T cell extravasation.
2000452	regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation	P	Any process that modulates the frequency, rate or extent of CD8-positive, alpha-beta cytotoxic T cell extravasation.
2000453	negative regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation	P	Any process that stops, prevents or reduces the frequency, rate or extent of CD8-positive, alpha-beta cytotoxic T cell extravasation.
2000454	positive regulation of CD8-positive, alpha-beta cytotoxic T cell extravasation	P	Any process that activates or increases the frequency, rate or extent of CD8-positive, alpha-beta cytotoxic T cell extravasation.
2000455	regulation of T-helper 17 cell extravasation	P	Any process that modulates the frequency, rate or extent of T-helper 17 cell extravasation.
2000456	negative regulation of T-helper 17 cell extravasation	P	Any process that stops, prevents or reduces the frequency, rate or extent of T-helper 17 cell extravasation.
2000457	positive regulation of T-helper 17 cell extravasation	P	Any process that activates or increases the frequency, rate or extent of T-helper 17 cell extravasation.
2000458	regulation of astrocyte chemotaxis	P	Any process that modulates the frequency, rate or extent of astrocyte chemotaxis.
2000459	negative regulation of astrocyte chemotaxis	P	Any process that stops, prevents or reduces the frequency, rate or extent of astrocyte chemotaxis.
2000463	positive regulation of excitatory postsynaptic potential	P	Any process that enhances the establishment or increases the extent of the excitatory postsynaptic potential (EPSP) which is a temporary increase in postsynaptic potential due to the flow of positively charged ions into the postsynaptic cell. The flow of ions that causes an EPSP is an excitatory postsynaptic current (EPSC) and makes it easier for the neuron to fire an action potential.
2000464	positive regulation of astrocyte chemotaxis	P	Any process that activates or increases the frequency, rate or extent of astrocyte chemotaxis.
2000465	regulation of glycogen (starch) synthase activity	P	Any process that modulates the frequency, rate or extent of glycogen (starch) synthase activity.
2000466	negative regulation of glycogen (starch) synthase activity	P	Any process that stops, prevents or reduces the frequency, rate or extent of glycogen (starch) synthase activity.
2000467	positive regulation of glycogen (starch) synthase activity	P	Any process that activates or increases the frequency, rate or extent of glycogen (starch) synthase activity.
2000468	regulation of peroxidase activity	P	Any process that modulates the frequency, rate or extent of peroxidase activity.
2000469	negative regulation of peroxidase activity	P	Any process that stops, prevents or reduces the frequency, rate or extent of peroxidase activity.
2000470	positive regulation of peroxidase activity	P	Any process that activates or increases the frequency, rate or extent of peroxidase activity.
2000471	regulation of hematopoietic stem cell migration	P	Any process that modulates the frequency, rate or extent of hematopoietic stem cell migration.
2000472	negative regulation of hematopoietic stem cell migration	P	Any process that stops, prevents or reduces the frequency, rate or extent of hematopoietic stem cell migration.
2000473	positive regulation of hematopoietic stem cell migration	P	Any process that activates or increases the frequency, rate or extent of hematopoietic stem cell migration.
2000474	regulation of opioid receptor signaling pathway	P	Any process that modulates the frequency, rate or extent of opioid receptor signaling pathway.
2000475	negative regulation of opioid receptor signaling pathway	P	Any process that stops, prevents or reduces the frequency, rate or extent of opioid receptor signaling pathway.
2000476	positive regulation of opioid receptor signaling pathway	P	Any process that activates or increases the frequency, rate or extent of opioid receptor signaling pathway.
2000477	regulation of metanephric glomerular visceral epithelial cell development	P	Any process that modulates the frequency, rate or extent of metanephric glomerular visceral epithelial cell development.
2000478	positive regulation of metanephric glomerular visceral epithelial cell development	P	Any process that activates or increases the frequency, rate or extent of metanephric glomerular visceral epithelial cell development.
2000479	regulation of cAMP-dependent protein kinase activity	P	Any process that modulates the frequency, rate or extent of cAMP-dependent protein kinase activity.
2000480	negative regulation of cAMP-dependent protein kinase activity	P	Any process that stops, prevents or reduces the frequency, rate or extent of cAMP-dependent protein kinase activity.
2000481	positive regulation of cAMP-dependent protein kinase activity	P	Any process that activates or increases the frequency, rate or extent of cAMP-dependent protein kinase activity.
2000482	regulation of interleukin-8 secretion	P	Any process that modulates the frequency, rate or extent of interleukin-8 secretion.
2000483	negative regulation of interleukin-8 secretion	P	Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-8 secretion.
2000484	positive regulation of interleukin-8 secretion	P	Any process that activates or increases the frequency, rate or extent of interleukin-8 secretion.
2000485	regulation of glutamine transport	P	Any process that modulates the frequency, rate or extent of glutamine transport.
2000486	negative regulation of glutamine transport	P	Any process that stops, prevents or reduces the frequency, rate or extent of glutamine transport.
2000487	positive regulation of glutamine transport	P	Any process that activates or increases the frequency, rate or extent of glutamine transport.
2000488	positive regulation of brassinosteroid biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of brassinosteroid biosynthetic process.
2000489	regulation of hepatic stellate cell activation	P	Any process that modulates the frequency, rate or extent of hepatic stellate cell activation.
2000490	negative regulation of hepatic stellate cell activation	P	Any process that stops, prevents or reduces the frequency, rate or extent of hepatic stellate cell activation.
2000491	positive regulation of hepatic stellate cell activation	P	Any process that activates or increases the frequency, rate or extent of hepatic stellate cell activation.
2000492	regulation of interleukin-18-mediated signaling pathway	P	Any process that modulates the frequency, rate or extent of interleukin-18-mediated signaling pathway.
2000493	negative regulation of interleukin-18-mediated signaling pathway	P	Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-18-mediated signaling pathway.
2000494	positive regulation of interleukin-18-mediated signaling pathway	P	Any process that activates or increases the frequency, rate or extent of interleukin-18-mediated signaling pathway.
2000495	regulation of cell proliferation involved in compound eye morphogenesis	P	Any process that modulates the frequency, rate or extent of cell proliferation involved in compound eye morphogenesis.
2000496	negative regulation of cell proliferation involved in compound eye morphogenesis	P	Any process that stops, prevents or reduces the frequency, rate or extent of cell proliferation involved in compound eye morphogenesis.
2000497	positive regulation of cell proliferation involved in compound eye morphogenesis	P	Any process that activates or increases the frequency, rate or extent of cell proliferation involved in compound eye morphogenesis.
2000501	regulation of natural killer cell chemotaxis	P	Any process that modulates the frequency, rate or extent of natural killer cell chemotaxis.
2000502	negative regulation of natural killer cell chemotaxis	P	Any process that stops, prevents or reduces the frequency, rate or extent of natural killer cell chemotaxis.
2000503	positive regulation of natural killer cell chemotaxis	P	Any process that activates or increases the frequency, rate or extent of natural killer cell chemotaxis.
2000504	positive regulation of blood vessel remodeling	P	Any process that activates or increases the frequency, rate or extent of blood vessel remodeling.
2000505	regulation of energy homeostasis	P	Any process that modulates the frequency, rate or extent of energy homeostasis.
2000506	negative regulation of energy homeostasis	P	Any process that stops, prevents or reduces the frequency, rate or extent of energy homeostasis.
2000507	positive regulation of energy homeostasis	P	Any process that activates or increases the frequency, rate or extent of energy homeostasis.
2000508	regulation of dendritic cell chemotaxis	P	Any process that modulates the frequency, rate or extent of dendritic cell chemotaxis.
2000509	negative regulation of dendritic cell chemotaxis	P	Any process that stops, prevents or reduces the frequency, rate or extent of dendritic cell chemotaxis.
2000510	positive regulation of dendritic cell chemotaxis	P	Any process that activates or increases the frequency, rate or extent of dendritic cell chemotaxis.
2000511	regulation of granzyme A production	P	Any process that modulates the frequency, rate or extent of granzyme A production.
2000512	negative regulation of granzyme A production	P	Any process that stops, prevents or reduces the frequency, rate or extent of granzyme A production.
2000513	positive regulation of granzyme A production	P	Any process that activates or increases the frequency, rate or extent of granzyme A production.
2000514	regulation of CD4-positive, alpha-beta T cell activation	P	Any process that modulates the frequency, rate or extent of CD4-positive, alpha-beta T cell activation.
2000515	negative regulation of CD4-positive, alpha-beta T cell activation	P	Any process that stops, prevents or reduces the frequency, rate or extent of CD4-positive, alpha-beta T cell activation.
2000516	positive regulation of CD4-positive, alpha-beta T cell activation	P	Any process that activates or increases the frequency, rate or extent of CD4-positive, alpha-beta T cell activation.
2000517	regulation of T-helper 1 cell activation	P	Any process that modulates the frequency, rate or extent of T-helper 1 cell activation.
2000518	negative regulation of T-helper 1 cell activation	P	Any process that stops, prevents or reduces the frequency, rate or extent of T-helper 1 cell activation.
2000519	positive regulation of T-helper 1 cell activation	P	Any process that activates or increases the frequency, rate or extent of T-helper 1 cell activation.
2000520	regulation of immunological synapse formation	P	Any process that modulates the frequency, rate or extent of immunological synapse formation.
2000521	negative regulation of immunological synapse formation	P	Any process that stops, prevents or reduces the frequency, rate or extent of immunological synapse formation.
2000522	positive regulation of immunological synapse formation	P	Any process that activates or increases the frequency, rate or extent of immunological synapse formation.
2000523	regulation of T cell costimulation	P	Any process that modulates the frequency, rate or extent of T cell costimulation.
2000524	negative regulation of T cell costimulation	P	Any process that stops, prevents or reduces the frequency, rate or extent of T cell costimulation.
2000525	positive regulation of T cell costimulation	P	Any process that activates or increases the frequency, rate or extent of T cell costimulation.
2000526	positive regulation of glycoprotein biosynthetic process involved in immunological synapse formation	P	Any positive regulation of glycoprotein biosynthetic process that is involved in immunological synapse formation.
2000527	regulation of myeloid dendritic cell chemotaxis	P	Any process that modulates the frequency, rate or extent of myeloid dendritic cell chemotaxis.
2000528	negative regulation of myeloid dendritic cell chemotaxis	P	Any process that stops, prevents or reduces the frequency, rate or extent of myeloid dendritic cell chemotaxis.
2000529	positive regulation of myeloid dendritic cell chemotaxis	P	Any process that activates or increases the frequency, rate or extent of myeloid dendritic cell chemotaxis.
2000531	regulation of fatty acid biosynthetic process by regulation of transcription from RNA polymerase II promoter	P	Any process that modulates the frequency, rate or extent of the biosynthesis of fatty acids, by modulating the frequency, rate or extent of transcription from an RNA polymerase II promoter.
2000532	regulation of renal albumin absorption	P	Any process that modulates the frequency, rate or extent of renal albumin absorption.
2000533	negative regulation of renal albumin absorption	P	Any process that stops, prevents or reduces the frequency, rate or extent of renal albumin absorption.
2000534	positive regulation of renal albumin absorption	P	Any process that activates or increases the frequency, rate or extent of renal albumin absorption.
2000535	regulation of entry of bacterium into host cell	P	Any process that modulates the frequency, rate or extent of entry of bacterium into host cell.
2000536	negative regulation of entry of bacterium into host cell	P	Any process that stops, prevents or reduces the frequency, rate or extent of entry of bacterium into host cell.
2000537	regulation of B cell chemotaxis	P	Any process that modulates the frequency, rate or extent of B cell chemotaxis.
2000538	positive regulation of B cell chemotaxis	P	Any process that activates or increases the frequency, rate or extent of B cell chemotaxis.
2000539	regulation of protein geranylgeranylation	P	Any process that modulates the frequency, rate or extent of protein geranylgeranylation.
2000540	negative regulation of protein geranylgeranylation	P	Any process that stops, prevents or reduces the frequency, rate or extent of protein geranylgeranylation.
2000541	positive regulation of protein geranylgeranylation	P	Any process that activates or increases the frequency, rate or extent of protein geranylgeranylation.
2000542	negative regulation of gastrulation	P	Any process that stops, prevents or reduces the frequency, rate or extent of gastrulation.
2000543	positive regulation of gastrulation	P	Any process that activates or increases the frequency, rate or extent of gastrulation.
2000544	regulation of endothelial cell chemotaxis to fibroblast growth factor	P	Any process that modulates the frequency, rate or extent of endothelial cell chemotaxis to fibroblast growth factor.
2000545	negative regulation of endothelial cell chemotaxis to fibroblast growth factor	P	Any process that stops, prevents or reduces the frequency, rate or extent of endothelial cell chemotaxis to fibroblast growth factor.
2000546	positive regulation of endothelial cell chemotaxis to fibroblast growth factor	P	Any process that activates or increases the frequency, rate or extent of endothelial cell chemotaxis to fibroblast growth factor.
2000547	regulation of dendritic cell dendrite assembly	P	Any process that modulates the frequency, rate or extent of dendritic cell dendrite assembly.
2000548	negative regulation of dendritic cell dendrite assembly	P	Any process that stops, prevents or reduces the frequency, rate or extent of dendritic cell dendrite assembly.
2000549	positive regulation of dendritic cell dendrite assembly	P	Any process that activates or increases the frequency, rate or extent of dendritic cell dendrite assembly.
2000550	negative regulation of B cell chemotaxis	P	Any process that stops, prevents or reduces the frequency, rate or extent of B cell chemotaxis.
2000551	regulation of T-helper 2 cell cytokine production	P	Any process that modulates the frequency, rate or extent of T-helper 2 cell cytokine production.
2000552	negative regulation of T-helper 2 cell cytokine production	P	Any process that stops, prevents or reduces the frequency, rate or extent of T-helper 2 cell cytokine production.
2000553	positive regulation of T-helper 2 cell cytokine production	P	Any process that activates or increases the frequency, rate or extent of T-helper 2 cell cytokine production.
2000554	regulation of T-helper 1 cell cytokine production	P	Any process that modulates the frequency, rate or extent of T-helper 1 cell cytokine production.
2000555	negative regulation of T-helper 1 cell cytokine production	P	Any process that stops, prevents or reduces the frequency, rate or extent of T-helper 1 cell cytokine production.
2000556	positive regulation of T-helper 1 cell cytokine production	P	Any process that activates or increases the frequency, rate or extent of T-helper 1 cell cytokine production.
2000557	regulation of immunoglobulin production in mucosal tissue	P	Any process that modulates the frequency, rate or extent of immunoglobulin production in mucosal tissue.
2000558	positive regulation of immunoglobulin production in mucosal tissue	P	Any process that activates or increases the frequency, rate or extent of immunoglobulin production in mucosal tissue.
2000559	regulation of CD24 biosynthetic process	P	Any process that modulates the frequency, rate or extent of CD24 biosynthetic process.
2000560	positive regulation of CD24 biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of CD24 biosynthetic process.
2000561	regulation of CD4-positive, alpha-beta T cell proliferation	P	Any process that modulates the frequency, rate or extent of CD4-positive, alpha-beta T cell proliferation.
2000562	negative regulation of CD4-positive, alpha-beta T cell proliferation	P	Any process that stops, prevents or reduces the frequency, rate or extent of CD4-positive, alpha-beta T cell proliferation.
2000563	positive regulation of CD4-positive, alpha-beta T cell proliferation	P	Any process that activates or increases the frequency, rate or extent of CD4-positive, alpha-beta T cell proliferation.
2000564	regulation of CD8-positive, alpha-beta T cell proliferation	P	Any process that modulates the frequency, rate or extent of CD8-positive, alpha-beta T cell proliferation.
2000565	negative regulation of CD8-positive, alpha-beta T cell proliferation	P	Any process that stops, prevents or reduces the frequency, rate or extent of CD8-positive, alpha-beta T cell proliferation.
2000566	positive regulation of CD8-positive, alpha-beta T cell proliferation	P	Any process that activates or increases the frequency, rate or extent of CD8-positive, alpha-beta T cell proliferation.
2000567	regulation of memory T cell activation	P	Any process that modulates the frequency, rate or extent of memory T cell activation.
2000568	positive regulation of memory T cell activation	P	Any process that activates or increases the frequency, rate or extent of memory T cell activation.
2000569	regulation of T-helper 2 cell activation	P	Any process that modulates the frequency, rate or extent of T-helper 2 cell activation.
2000570	positive regulation of T-helper 2 cell activation	P	Any process that activates or increases the frequency, rate or extent of T-helper 2 cell activation.
2000571	regulation of interleukin-4-dependent isotype switching to IgE isotypes	P	Any process that modulates the frequency, rate or extent of interleukin-4-dependent isotype switching to IgE isotypes.
2000572	positive regulation of interleukin-4-dependent isotype switching to IgE isotypes	P	Any process that activates or increases the frequency, rate or extent of interleukin-4-dependent isotype switching to IgE isotypes.
2000573	positive regulation of DNA biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of DNA biosynthetic process.
2000574	regulation of microtubule motor activity	P	Any process that modulates the frequency, rate or extent of microtubule motor activity.
2000575	negative regulation of microtubule motor activity	P	Any process that stops, prevents or reduces the frequency, rate or extent of microtubule motor activity.
2000576	positive regulation of microtubule motor activity	P	Any process that activates or increases the frequency, rate or extent of microtubule motor activity.
2000577	regulation of ATP-dependent microtubule motor activity, minus-end-directed	P	Any process that modulates the frequency, rate or extent of ATP-dependent microtubule motor activity, minus-end-directed.
2000578	negative regulation of ATP-dependent microtubule motor activity, minus-end-directed	P	Any process that stops, prevents or reduces the frequency, rate or extent of ATP-dependent microtubule motor activity, minus-end-directed.
2000579	positive regulation of ATP-dependent microtubule motor activity, minus-end-directed	P	Any process that activates or increases the frequency, rate or extent of ATP-dependent microtubule motor activity, minus-end-directed.
2000580	regulation of ATP-dependent microtubule motor activity, plus-end-directed	P	Any process that modulates the frequency, rate or extent of ATP-dependent microtubule motor activity, plus-end-directed.
2000581	negative regulation of ATP-dependent microtubule motor activity, plus-end-directed	P	Any process that stops, prevents or reduces the frequency, rate or extent of ATP-dependent microtubule motor activity, plus-end-directed.
2000582	positive regulation of ATP-dependent microtubule motor activity, plus-end-directed	P	Any process that activates or increases the frequency, rate or extent of ATP-dependent microtubule motor activity, plus-end-directed.
2000583	regulation of platelet-derived growth factor receptor-alpha signaling pathway	P	Any process that modulates the frequency, rate or extent of platelet-derived growth factor receptor-alpha signaling pathway.
2000584	negative regulation of platelet-derived growth factor receptor-alpha signaling pathway	P	Any process that stops, prevents or reduces the frequency, rate or extent of platelet-derived growth factor receptor-alpha signaling pathway.
2000585	positive regulation of platelet-derived growth factor receptor-alpha signaling pathway	P	Any process that activates or increases the frequency, rate or extent of platelet-derived growth factor receptor-alpha signaling pathway.
2000586	regulation of platelet-derived growth factor receptor-beta signaling pathway	P	Any process that modulates the frequency, rate or extent of platelet-derived growth factor receptor-beta signaling pathway.
2000587	negative regulation of platelet-derived growth factor receptor-beta signaling pathway	P	Any process that stops, prevents or reduces the frequency, rate or extent of platelet-derived growth factor receptor-beta signaling pathway.
2000588	positive regulation of platelet-derived growth factor receptor-beta signaling pathway	P	Any process that activates or increases the frequency, rate or extent of platelet-derived growth factor receptor-beta signaling pathway.
2000589	regulation of metanephric mesenchymal cell migration	P	Any process that modulates the frequency, rate or extent of metanephric mesenchymal cell migration.
2000590	negative regulation of metanephric mesenchymal cell migration	P	Any process that stops, prevents or reduces the frequency, rate or extent of metanephric mesenchymal cell migration.
2000591	positive regulation of metanephric mesenchymal cell migration	P	Any process that activates or increases the frequency, rate or extent of metanephric mesenchymal cell migration.
2000592	regulation of metanephric DCT cell differentiation	P	Any process that modulates the frequency, rate or extent of metanephric DCT cell differentiation.
2000593	negative regulation of metanephric DCT cell differentiation	P	Any process that stops, prevents or reduces the frequency, rate or extent of metanephric DCT cell differentiation.
2000594	positive regulation of metanephric DCT cell differentiation	P	Any process that activates or increases the frequency, rate or extent of metanephric DCT cell differentiation.
2000595	regulation of optic nerve formation	P	Any process that modulates the frequency, rate or extent of optic nerve formation.
2000596	negative regulation of optic nerve formation	P	Any process that stops, prevents or reduces the frequency, rate or extent of optic nerve formation.
2000597	positive regulation of optic nerve formation	P	Any process that activates or increases the frequency, rate or extent of optic nerve formation.
2000601	positive regulation of Arp2/3 complex-mediated actin nucleation	P	Any process that activates or increases the frequency, rate or extent of Arp2/3 complex-mediated actin nucleation.
2000603	regulation of secondary growth	P	Any process that modulates the frequency, rate or extent of secondary growth.
2000604	negative regulation of secondary growth	P	Any process that stops, prevents or reduces the frequency, rate or extent of secondary growth.
2000605	positive regulation of secondary growth	P	Any process that activates or increases the frequency, rate or extent of secondary growth.
2000606	regulation of cell proliferation involved in mesonephros development	P	Any process that modulates the frequency, rate or extent of cell proliferation involved in mesonephros development.
2000607	negative regulation of cell proliferation involved in mesonephros development	P	Any process that stops, prevents or reduces the frequency, rate or extent of cell proliferation involved in mesonephros development.
2000608	positive regulation of cell proliferation involved in mesonephros development	P	Any process that activates or increases the frequency, rate or extent of cell proliferation involved in mesonephros development.
2000609	regulation of thyroid hormone generation	P	Any process that modulates the frequency, rate or extent of thyroid hormone generation.
2000610	negative regulation of thyroid hormone generation	P	Any process that stops, prevents or reduces the frequency, rate or extent of thyroid hormone generation.
2000611	positive regulation of thyroid hormone generation	P	Any process that activates or increases the frequency, rate or extent of thyroid hormone generation.
2000612	regulation of thyroid-stimulating hormone secretion	P	Any process that modulates the frequency, rate or extent of thyroid-stimulating hormone secretion.
2000613	negative regulation of thyroid-stimulating hormone secretion	P	Any process that stops, prevents or reduces the frequency, rate or extent of thyroid-stimulating hormone secretion.
2000614	positive regulation of thyroid-stimulating hormone secretion	P	Any process that activates or increases the frequency, rate or extent of thyroid-stimulating hormone secretion.
2000615	regulation of histone H3-K9 acetylation	P	Any process that modulates the frequency, rate or extent of histone H3-K9 acetylation.
2000616	negative regulation of histone H3-K9 acetylation	P	Any process that stops, prevents or reduces the frequency, rate or extent of histone H3-K9 acetylation.
2000617	positive regulation of histone H3-K9 acetylation	P	Any process that activates or increases the frequency, rate or extent of histone H3-K9 acetylation.
2000618	regulation of histone H4-K16 acetylation	P	Any process that modulates the frequency, rate or extent of histone H4-K16 acetylation.
2000619	negative regulation of histone H4-K16 acetylation	P	Any process that stops, prevents or reduces the frequency, rate or extent of histone H4-K16 acetylation.
2000620	positive regulation of histone H4-K16 acetylation	P	Any process that activates or increases the frequency, rate or extent of histone H4-K16 acetylation.
2000621	regulation of DNA replication termination	P	Any process that modulates the frequency, rate or extent of DNA replication termination.
2000622	regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	P	Any process that modulates the frequency, rate or extent of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay.
2000623	negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	P	Any process that stops, prevents or reduces the frequency, rate or extent of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay.
2000624	positive regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	P	Any process that activates or increases the frequency, rate or extent of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay.
2000625	regulation of miRNA catabolic process	P	Any process that modulates the frequency, rate or extent of miRNA catabolic process.
2000626	negative regulation of miRNA catabolic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of miRNA catabolic process.
2000627	positive regulation of miRNA catabolic process	P	Any process that activates or increases the frequency, rate or extent of miRNA catabolic process.
2000628	regulation of miRNA metabolic process	P	Any process that modulates the frequency, rate or extent of miRNA metabolic process.
2000629	negative regulation of miRNA metabolic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of miRNA metabolic process.
2000630	positive regulation of miRNA metabolic process	P	Any process that activates or increases the frequency, rate or extent of miRNA metabolic process.
2000631	regulation of pre-miRNA processing	P	Any process that modulates the frequency, rate or extent of pre-microRNA processing.
2000632	negative regulation of pre-miRNA processing	P	Any process that stops, prevents or reduces the frequency, rate or extent of pre-microRNA processing.
2000633	positive regulation of pre-miRNA processing	P	Any process that activates or increases the frequency, rate or extent of pre-microRNA processing.
2000634	regulation of primary miRNA processing	P	Any process that modulates the frequency, rate or extent of primary microRNA processing.
2000635	negative regulation of primary miRNA processing	P	Any process that stops, prevents or reduces the frequency, rate or extent of primary microRNA processing.
2000636	positive regulation of primary miRNA processing	P	Any process that activates or increases the frequency, rate or extent of primary microRNA processing.
2000637	positive regulation of gene silencing by miRNA	P	Any process that activates or increases the frequency, rate or extent of gene silencing by miRNA.
2000638	regulation of SREBP signaling pathway	P	Any process that modulates the frequency, rate or extent of the SREBP signaling pathway.
2000639	negative regulation of SREBP signaling pathway	P	Any process that stops, prevents or reduces the frequency, rate or extent of the SREBP signaling pathway.
2000640	positive regulation of SREBP signaling pathway	P	Any process that activates or increases the frequency, rate or extent of the SREBP signaling pathway.
2000641	regulation of early endosome to late endosome transport	P	Any process that modulates the frequency, rate or extent of early endosome to late endosome transport.
2000642	negative regulation of early endosome to late endosome transport	P	Any process that stops, prevents or reduces the frequency, rate or extent of early endosome to late endosome transport.
2000643	positive regulation of early endosome to late endosome transport	P	Any process that activates or increases the frequency, rate or extent of early endosome to late endosome transport.
2000644	regulation of receptor catabolic process	P	Any process that modulates the frequency, rate or extent of receptor catabolic process.
2000645	negative regulation of receptor catabolic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of receptor catabolic process.
2000646	positive regulation of receptor catabolic process	P	Any process that activates or increases the frequency, rate or extent of receptor catabolic process.
2000647	negative regulation of stem cell proliferation	P	Any process that stops, prevents or reduces the frequency, rate or extent of stem cell proliferation.
2000648	positive regulation of stem cell proliferation	P	Any process that activates or increases the frequency, rate or extent of stem cell proliferation.
2000649	regulation of sodium ion transmembrane transporter activity	P	Any process that modulates the frequency, rate or extent of sodium ion transmembrane transporter activity.
2000650	negative regulation of sodium ion transmembrane transporter activity	P	Any process that stops, prevents or reduces the frequency, rate or extent of sodium ion transmembrane transporter activity.
2000651	positive regulation of sodium ion transmembrane transporter activity	P	Any process that activates or increases the frequency, rate or extent of sodium ion transmembrane transporter activity.
2000652	regulation of secondary cell wall biogenesis	P	Any process that modulates the frequency, rate or extent of secondary cell wall biogenesis.
2000653	regulation of genetic imprinting	P	Any process that modulates the frequency, rate or extent of genetic imprinting.
2000654	regulation of cellular response to testosterone stimulus	P	Any process that modulates the frequency, rate or extent of cellular response to testosterone stimulus.
2000655	negative regulation of cellular response to testosterone stimulus	P	Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to testosterone stimulus.
2000656	regulation of apolipoprotein binding	P	Any process that modulates the frequency, rate or extent of apolipoprotein binding.
2000657	negative regulation of apolipoprotein binding	P	Any process that stops, prevents or reduces the frequency, rate or extent of apolipoprotein binding.
2000658	positive regulation of apolipoprotein binding	P	Any process that activates or increases the frequency, rate or extent of apolipoprotein binding.
2000659	regulation of interleukin-1-mediated signaling pathway	P	Any process that modulates the frequency, rate or extent of interleukin-1-mediated signaling pathway.
2000660	negative regulation of interleukin-1-mediated signaling pathway	P	Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-1-mediated signaling pathway.
2000661	positive regulation of interleukin-1-mediated signaling pathway	P	Any process that activates or increases the frequency, rate or extent of interleukin-1-mediated signaling pathway.
2000662	regulation of interleukin-5 secretion	P	Any process that modulates the frequency, rate or extent of interleukin-5 secretion.
2000663	negative regulation of interleukin-5 secretion	P	Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-5 secretion.
2000664	positive regulation of interleukin-5 secretion	P	Any process that activates or increases the frequency, rate or extent of interleukin-5 secretion.
2000665	regulation of interleukin-13 secretion	P	Any process that modulates the frequency, rate or extent of interleukin-13 secretion.
2000666	negative regulation of interleukin-13 secretion	P	Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-13 secretion.
2000667	positive regulation of interleukin-13 secretion	P	Any process that activates or increases the frequency, rate or extent of interleukin-13 secretion.
2000668	regulation of dendritic cell apoptotic process	P	Any process that modulates the frequency, rate or extent of dendritic cell apoptotic process.
2000669	negative regulation of dendritic cell apoptotic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of dendritic cell apoptotic process.
2000670	positive regulation of dendritic cell apoptotic process	P	Any process that activates or increases the frequency, rate or extent of dendritic cell apoptotic process.
2000671	regulation of motor neuron apoptotic process	P	Any process that modulates the frequency, rate or extent of motor neuron apoptotic process.
2000672	negative regulation of motor neuron apoptotic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of motor neuron apoptotic process.
2000673	positive regulation of motor neuron apoptotic process	P	Any process that activates or increases the frequency, rate or extent of motor neuron apoptotic process.
2000674	regulation of type B pancreatic cell apoptotic process	P	Any process that modulates the frequency, rate or extent of type B pancreatic cell apoptotic process.
2000675	negative regulation of type B pancreatic cell apoptotic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of type B pancreatic cell apoptotic process.
2000676	positive regulation of type B pancreatic cell apoptotic process	P	Any process that activates or increases the frequency, rate or extent of type B pancreatic cell apoptotic process.
2000677	regulation of transcription regulatory region DNA binding	P	Any process that modulates the frequency, rate or extent of transcription regulatory region DNA binding.
2000678	negative regulation of transcription regulatory region DNA binding	P	Any process that stops, prevents or reduces the frequency, rate or extent of transcription regulatory region DNA binding.
2000679	positive regulation of transcription regulatory region DNA binding	P	Any process that activates or increases the frequency, rate or extent of transcription regulatory region DNA binding.
2000680	regulation of rubidium ion transport	P	Any process that modulates the frequency, rate or extent of rubidium ion transport.
2000681	negative regulation of rubidium ion transport	P	Any process that stops, prevents or reduces the frequency, rate or extent of rubidium ion transport.
2000682	positive regulation of rubidium ion transport	P	Any process that activates or increases the frequency, rate or extent of rubidium ion transport.
2000683	regulation of cellular response to X-ray	P	Any process that modulates the frequency, rate or extent of cellular response to X-ray.
2000684	negative regulation of cellular response to X-ray	P	Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to X-ray.
2000685	positive regulation of cellular response to X-ray	P	Any process that activates or increases the frequency, rate or extent of cellular response to X-ray.
2000686	regulation of rubidium ion transmembrane transporter activity	P	Any process that modulates the frequency, rate or extent of rubidium ion transmembrane transporter activity.
2000687	negative regulation of rubidium ion transmembrane transporter activity	P	Any process that stops, prevents or reduces the frequency, rate or extent of rubidium ion transmembrane transporter activity.
2000688	positive regulation of rubidium ion transmembrane transporter activity	P	Any process that activates or increases the frequency, rate or extent of rubidium ion transmembrane transporter activity.
2000689	actomyosin contractile ring assembly actin filament organization	P	An actin filament organization process that contributes to actomyosin contractile ring assembly during cytokinesis.
2000690	regulation of cardiac muscle cell myoblast differentiation	P	Any process that modulates the frequency, rate or extent of cardiac muscle cell myoblast differentiation.
2000691	negative regulation of cardiac muscle cell myoblast differentiation	P	Any process that stops, prevents or reduces the frequency, rate or extent of cardiac muscle cell myoblast differentiation.
2000692	negative regulation of seed maturation	P	Any process that stops, prevents or reduces the frequency, rate or extent of seed maturation.
2000693	positive regulation of seed maturation	P	Any process that activates or increases the frequency, rate or extent of seed maturation.
2000694	regulation of phragmoplast microtubule organization	P	Any process that modulates the frequency, rate or extent of phragmoplast microtubule organization.
2000696	regulation of epithelial cell differentiation involved in kidney development	P	Any process that modulates the frequency, rate or extent of epithelial cell differentiation involved in kidney development.
2000697	negative regulation of epithelial cell differentiation involved in kidney development	P	Any process that stops, prevents or reduces the frequency, rate or extent of epithelial cell differentiation involved in kidney development.
2000698	positive regulation of epithelial cell differentiation involved in kidney development	P	Any process that activates or increases the frequency, rate or extent of epithelial cell differentiation involved in kidney development.
2000699	fibroblast growth factor receptor signaling pathway involved in ureteric bud formation	P	The series of molecular signals generated as a consequence of a fibroblast growth factor receptor binding to one of its physiological ligands that contributes to the formation of the ureteric bud from the Wolffian duct.
2000700	positive regulation of cardiac muscle cell myoblast differentiation	P	Any process that activates or increases the frequency, rate or extent of cardiac muscle cell myoblast differentiation.
2000701	glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation	P	The series of molecular signals generated as a consequence of a glial cell-derived neurotrophic factor receptor binding to one of its physiological ligands that contributes to the formation of the ureteric bud from the Wolffian duct.
2000702	regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation	P	Any process that modulates the frequency, rate or extent of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation.
2000703	negative regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation	P	Any process that stops, prevents or reduces the frequency, rate or extent of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation.
2000704	positive regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation	P	Any process that activates or increases the frequency, rate or extent of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation.
2000705	regulation of dense core granule biogenesis	P	Any process that modulates the frequency, rate or extent of dense core granule biogenesis.
2000706	negative regulation of dense core granule biogenesis	P	Any process that stops, prevents or reduces the frequency, rate or extent of dense core granule biogenesis.
2000707	positive regulation of dense core granule biogenesis	P	Any process that activates or increases the frequency, rate or extent of dense core granule biogenesis.
2000708	myosin filament organization involved in cytokinetic actomyosin contractile ring assembly	P	A myosin filament organization process that contributes to actomyosin contractile ring assembly during cytokinesis.
2000709	regulation of maintenance of meiotic sister chromatid cohesion, centromeric	P	Any process that modulates the frequency, rate or extent of maintenance of meiotic sister chromatid cohesion in the centromeric region.
2000710	negative regulation of maintenance of meiotic sister chromatid cohesion, centromeric	P	Any process that stops, prevents or reduces the frequency, rate or extent of maintenance of meiotic sister chromatid cohesion in the centromeric region.
2000711	positive regulation of maintenance of meiotic sister chromatid cohesion, centromeric	P	Any process that activates or increases the frequency, rate or extent of maintenance of meiotic sister chromatid cohesion in the centromeric region.
2000712	regulation of maintenance of meiotic sister chromatid cohesion, arms	P	Any process that modulates the frequency, rate or extent of maintenance of meiotic sister chromatid cohesion along the chromosome arms.
2000713	negative regulation of maintenance of meiotic sister chromatid cohesion, arms	P	Any process that stops, prevents or reduces the frequency, rate or extent of maintenance of meiotic sister chromatid cohesion along the chromosome arms.
2000714	positive regulation of maintenance of meiotic sister chromatid cohesion, arms	P	Any process that activates or increases the frequency, rate or extent of maintenance of meiotic sister chromatid cohesion along the chromosome arms.
2000715	regulation of maintenance of mitotic sister chromatid cohesion, arms	P	Any process that modulates the frequency, rate or extent of maintenance of mitotic sister chromatid cohesion along the chromosome arms.
2000716	negative regulation of maintenance of mitotic sister chromatid cohesion, arms	P	Any process that stops, prevents or reduces the frequency, rate or extent of maintenance of mitotic sister chromatid cohesion along the chromosome arms.
2000717	positive regulation of maintenance of mitotic sister chromatid cohesion, arms	P	Any process that activates or increases the frequency, rate or extent of maintenance of mitotic sister chromatid cohesion along the chromosome arms.
2000718	regulation of maintenance of mitotic sister chromatid cohesion, centromeric	P	Any process that modulates the frequency, rate or extent of maintenance of mitotic sister chromatid cohesion in the centromeric region.
2000719	negative regulation of maintenance of mitotic sister chromatid cohesion, centromeric	P	Any process that stops, prevents or reduces the frequency, rate or extent of maintenance of mitotic sister chromatid cohesion in the centromeric region.
2000720	positive regulation of maintenance of mitotic sister chromatid cohesion, centromeric	P	Any process that activates or increases the frequency, rate or extent of maintenance of mitotic sister chromatid cohesion in the centromeric region.
2000721	positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation	P	Any positive regulation of transcription from RNA polymerase II promoter that is involved in smooth muscle cell differentiation.
2000722	regulation of cardiac vascular smooth muscle cell differentiation	P	Any process that modulates the frequency, rate or extent of cardiac vascular smooth muscle cell differentiation.
2000723	negative regulation of cardiac vascular smooth muscle cell differentiation	P	Any process that stops, prevents or reduces the frequency, rate or extent of cardiac vascular smooth muscle cell differentiation.
2000724	positive regulation of cardiac vascular smooth muscle cell differentiation	P	Any process that activates or increases the frequency, rate or extent of cardiac vascular smooth muscle cell differentiation.
2000725	regulation of cardiac muscle cell differentiation	P	Any process that modulates the frequency, rate or extent of cardiac muscle cell differentiation.
2000726	negative regulation of cardiac muscle cell differentiation	P	Any process that stops, prevents or reduces the frequency, rate or extent of cardiac muscle cell differentiation.
2000727	positive regulation of cardiac muscle cell differentiation	P	Any process that activates or increases the frequency, rate or extent of cardiac muscle cell differentiation.
2000728	regulation of mRNA export from nucleus in response to heat stress	P	Any process that modulates the frequency, rate or extent of mRNA export from nucleus in response to heat stress.
2000729	positive regulation of mesenchymal cell proliferation involved in ureter development	P	Any process that activates or increases the frequency, rate or extent of mesenchymal cell proliferation involved in ureter development.
2000730	regulation of termination of RNA polymerase I transcription	P	Any process that modulates the frequency, rate or extent of termination of RNA polymerase I transcription.
2000731	negative regulation of termination of RNA polymerase I transcription	P	Any process that stops, prevents or reduces the frequency, rate or extent of termination of RNA polymerase I transcription.
2000732	positive regulation of termination of RNA polymerase I transcription	P	Any process that activates or increases the frequency, rate or extent of termination of RNA polymerase I transcription.
2000733	regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation	P	Any process that modulates the frequency, rate or extent of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation.
2000734	negative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation	P	Any process that stops, prevents or reduces the frequency, rate or extent of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation.
2000735	positive regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation	P	Any process that activates or increases the frequency, rate or extent of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation.
2000736	regulation of stem cell differentiation	P	Any process that modulates the frequency, rate or extent of stem cell differentiation.
2000737	negative regulation of stem cell differentiation	P	Any process that stops, prevents or reduces the frequency, rate or extent of stem cell differentiation.
2000738	positive regulation of stem cell differentiation	P	Any process that activates or increases the frequency, rate or extent of stem cell differentiation.
2000739	regulation of mesenchymal stem cell differentiation	P	Any process that modulates the frequency, rate or extent of mesenchymal stem cell differentiation.
2000740	negative regulation of mesenchymal stem cell differentiation	P	Any process that stops, prevents or reduces the frequency, rate or extent of mesenchymal stem cell differentiation.
2000741	positive regulation of mesenchymal stem cell differentiation	P	Any process that activates or increases the frequency, rate or extent of mesenchymal stem cell differentiation.
2000742	regulation of anterior head development	P	Any process that modulates the frequency, rate or extent of anterior head development.
2000743	negative regulation of anterior head development	P	Any process that stops, prevents or reduces the frequency, rate or extent of anterior head development.
2000744	positive regulation of anterior head development	P	Any process that activates or increases the frequency, rate or extent of anterior head development.
2000746	regulation of defecation rhythm	P	Any process that modulates the frequency, rate or extent of defecation rhythm.
2000747	negative regulation of defecation rhythm	P	Any process that stops, prevents or reduces the frequency, rate or extent of defecation rhythm.
2000748	positive regulation of defecation rhythm	P	Any process that activates or increases the frequency, rate or extent of defecation rhythm.
2000749	positive regulation of chromatin silencing at rDNA	P	Any process that activates or increases the frequency, rate or extent of chromatin silencing at rDNA.
2000750	negative regulation of establishment or maintenance of bipolar cell polarity regulating cell shape	P	Any process that stops, prevents or reduces the frequency, rate or extent of establishment or maintenance of bipolar cell polarity regulating cell shape.
2000751	histone H3-T3 phosphorylation involved in chromosome passenger complex localization to kinetochore	P	Any histone H3-T3 phosphorylation that is involved in chromosome passenger complex localization to kinetochore.
2000752	regulation of glucosylceramide catabolic process	P	Any process that modulates the frequency, rate or extent of glucosylceramide catabolic process.
2000753	positive regulation of glucosylceramide catabolic process	P	Any process that activates or increases the frequency, rate or extent of glucosylceramide catabolic process.
2000754	regulation of sphingomyelin catabolic process	P	Any process that modulates the frequency, rate or extent of sphingomyelin catabolic process.
2000755	positive regulation of sphingomyelin catabolic process	P	Any process that activates or increases the frequency, rate or extent of sphingomyelin catabolic process.
2000756	regulation of peptidyl-lysine acetylation	P	Any process that modulates the frequency, rate or extent of peptidyl-lysine acetylation.
2000757	negative regulation of peptidyl-lysine acetylation	P	Any process that stops, prevents or reduces the frequency, rate or extent of peptidyl-lysine acetylation.
2000758	positive regulation of peptidyl-lysine acetylation	P	Any process that activates or increases the frequency, rate or extent of peptidyl-lysine acetylation.
2000759	regulation of N-terminal peptidyl-lysine acetylation	P	Any process that modulates the frequency, rate or extent of N-terminal peptidyl-lysine acetylation.
2000760	negative regulation of N-terminal peptidyl-lysine acetylation	P	Any process that stops, prevents or reduces the frequency, rate or extent of N-terminal peptidyl-lysine acetylation.
2000761	positive regulation of N-terminal peptidyl-lysine acetylation	P	Any process that activates or increases the frequency, rate or extent of N-terminal peptidyl-lysine acetylation.
2000762	regulation of phenylpropanoid metabolic process	P	Any process that modulates the frequency, rate or extent of phenylpropanoid metabolic process.
2000763	positive regulation of transcription from RNA polymerase II promoter involved in norepinephrine biosynthetic process	P	Any positive regulation of transcription from RNA polymerase II promoter that is involved in norepinephrine biosynthetic process.
2000764	positive regulation of semaphorin-plexin signaling pathway involved in outflow tract morphogenesis	P	Any process that activates or increases the frequency, rate or extent of semaphorin-plexin signaling pathway involved in outflow tract morphogenesis.
2000765	regulation of cytoplasmic translation	P	Any process that modulates the frequency, rate or extent of cytoplasmic translation.
2000766	negative regulation of cytoplasmic translation	P	Any process that stops, prevents or reduces the frequency, rate or extent of cytoplasmic translation.
2000767	positive regulation of cytoplasmic translation	P	Any process that activates or increases the frequency, rate or extent of cytoplasmic translation.
2000768	positive regulation of nephron tubule epithelial cell differentiation	P	Any process that activates or increases the frequency, rate or extent of nephron tubule epithelial cell differentiation.
2000769	regulation of establishment or maintenance of cell polarity regulating cell shape	P	Any process that modulates the frequency, rate or extent of establishment or maintenance of cell polarity regulating cell shape.
2000770	negative regulation of establishment or maintenance of cell polarity regulating cell shape	P	Any process that stops, prevents or reduces the frequency, rate or extent of establishment or maintenance of cell polarity regulating cell shape.
2000771	positive regulation of establishment or maintenance of cell polarity regulating cell shape	P	Any process that activates or increases the frequency, rate or extent of establishment or maintenance of cell polarity regulating cell shape.
2000772	regulation of cellular senescence	P	Any process that modulates the frequency, rate or extent of cellular senescence.
2000773	negative regulation of cellular senescence	P	Any process that stops, prevents or reduces the frequency, rate or extent of cellular senescence.
2000774	positive regulation of cellular senescence	P	Any process that activates or increases the frequency, rate or extent of cellular senescence.
2000775	histone H3-S10 phosphorylation involved in chromosome condensation	P	Any histone H3-S10 phosphorylation that is involved in chromosome condensation.
2000776	histone H4 acetylation involved in response to DNA damage stimulus	P	Any histone H4 acetylation that is involved in a response to DNA damage stimulus.
2000777	positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia	P	Any positive regulation of proteasomal ubiquitin-dependent protein catabolic process that is involved in a cellular response to hypoxia.
2000778	positive regulation of interleukin-6 secretion	P	Any process that activates or increases the frequency, rate or extent of interleukin-6 secretion.
2000779	regulation of double-strand break repair	P	Any process that modulates the frequency, rate or extent of double-strand break repair.
2000780	negative regulation of double-strand break repair	P	Any process that stops, prevents or reduces the frequency, rate or extent of double-strand break repair.
2000781	positive regulation of double-strand break repair	P	Any process that activates or increases the frequency, rate or extent of double-strand break repair.
2000782	regulation of establishment of cell polarity regulating cell shape	P	Any process that modulates the frequency, rate or extent of establishment of cell polarity regulating cell shape.
2000783	negative regulation of establishment of cell polarity regulating cell shape	P	Any process that stops, prevents or reduces the frequency, rate or extent of establishment of cell polarity regulating cell shape.
2000784	positive regulation of establishment of cell polarity regulating cell shape	P	Any process that activates or increases the frequency, rate or extent of establishment of cell polarity regulating cell shape.
2000785	regulation of autophagosome assembly	P	Any process that modulates the frequency, rate or extent of autophagosome assembly.
2000786	positive regulation of autophagosome assembly	P	Any process that activates or increases the frequency, rate or extent of autophagic vacuole assembly.
2000787	regulation of venous endothelial cell fate commitment	P	Any process that modulates the frequency, rate or extent of venous endothelial cell fate commitment.
2000788	negative regulation of venous endothelial cell fate commitment	P	Any process that stops, prevents or reduces the frequency, rate or extent of venous endothelial cell fate commitment.
2000789	positive regulation of venous endothelial cell fate commitment	P	Any process that activates or increases the frequency, rate or extent of venous endothelial cell fate commitment.
2000790	regulation of mesenchymal cell proliferation involved in lung development	P	Any process that modulates the frequency, rate or extent of mesenchymal cell proliferation involved in lung development.
2000791	negative regulation of mesenchymal cell proliferation involved in lung development	P	Any process that stops, prevents or reduces the frequency, rate or extent of mesenchymal cell proliferation involved in lung development.
2000792	positive regulation of mesenchymal cell proliferation involved in lung development	P	Any process that activates or increases the frequency, rate or extent of mesenchymal cell proliferation involved in lung development.
2000793	cell proliferation involved in heart valve development	P	Any cell proliferation that is involved in heart valve development.
2000794	regulation of epithelial cell proliferation involved in lung morphogenesis	P	Any process that modulates the frequency, rate or extent of epithelial cell proliferation involved in lung morphogenesis.
2000795	negative regulation of epithelial cell proliferation involved in lung morphogenesis	P	Any process that stops, prevents or reduces the frequency, rate or extent of epithelial cell proliferation involved in lung morphogenesis.
2000796	Notch signaling pathway involved in negative regulation of venous endothelial cell fate commitment	P	Any Notch signaling pathway that is involved in negative regulation of venous endothelial cell fate commitment.
2000797	regulation of amniotic stem cell differentiation	P	Any process that modulates the frequency, rate or extent of amniotic stem cell differentiation.
2000798	negative regulation of amniotic stem cell differentiation	P	Any process that stops, prevents or reduces the frequency, rate or extent of amniotic stem cell differentiation.
2000799	positive regulation of amniotic stem cell differentiation	P	Any process that activates or increases the frequency, rate or extent of amniotic stem cell differentiation.
2000800	regulation of endocardial cushion to mesenchymal transition involved in heart valve formation	P	Any process that modulates the frequency, rate or extent of endocardial cushion to mesenchymal transition involved in heart valve formation.
2000801	negative regulation of endocardial cushion to mesenchymal transition involved in heart valve formation	P	Any process that stops, prevents or reduces the frequency, rate or extent of endocardial cushion to mesenchymal transition involved in heart valve formation.
2000802	positive regulation of endocardial cushion to mesenchymal transition involved in heart valve formation	P	Any process that activates or increases the frequency, rate or extent of endocardial cushion to mesenchymal transition involved in heart valve formation.
2000803	endosomal signal transduction	P	The process in which a signal is passed on to downstream components located at the endosome. Endosomes can provide important intracellular signaling platforms and provide spatial and temporal control over signal transduction.
2000804	regulation of termination of RNA polymerase II transcription, poly(A)-coupled	P	Any process that modulates the frequency, rate or extent of termination of RNA polymerase II transcription, poly(A)-coupled.
2000805	negative regulation of termination of RNA polymerase II transcription, poly(A)-coupled	P	Any process that stops, prevents or reduces the frequency, rate or extent of termination of RNA polymerase II transcription, poly(A)-coupled.
2000806	positive regulation of termination of RNA polymerase II transcription, poly(A)-coupled	P	Any process that activates or increases the frequency, rate or extent of termination of RNA polymerase II transcription, poly(A)-coupled.
2000807	regulation of synaptic vesicle clustering	P	Any process that modulates the frequency, rate or extent of synaptic vesicle clustering.
2000808	negative regulation of synaptic vesicle clustering	P	Any process that stops, prevents or reduces the frequency, rate or extent of synaptic vesicle clustering.
2000809	positive regulation of synaptic vesicle clustering	P	Any process that activates or increases the frequency, rate or extent of synaptic vesicle clustering.
2000810	regulation of bicellular tight junction assembly	P	Any process that modulates the frequency, rate or extent of tight junction assembly.
2000811	negative regulation of anoikis	P	Any process that stops, prevents or reduces the frequency, rate or extent of anoikis.
2000812	regulation of barbed-end actin filament capping	P	Any process that modulates the frequency, rate or extent of barbed-end actin filament capping.
2000813	negative regulation of barbed-end actin filament capping	P	Any process that stops, prevents or reduces the frequency, rate or extent of barbed-end actin filament capping.
2000814	positive regulation of barbed-end actin filament capping	P	Any process that activates or increases the frequency, rate or extent of barbed-end actin filament capping.
2000815	regulation of mRNA stability involved in response to oxidative stress	P	A process of regulation of mRNA stability that is involved in a response to oxidative stress.
2000816	negative regulation of mitotic sister chromatid separation	P	Any process that stops, prevents or reduces the frequency, rate or extent of mitotic sister chromatid separation.
2000817	regulation of histone H3-T3 phosphorylation involved in chromosome passenger complex localization to kinetochore	P	Any regulation of histone H3-T3 phosphorylation that is involved in chromosome passenger complex localization to kinetochore.
2000818	negative regulation of myoblast proliferation	P	Any process that stops, prevents or reduces the frequency, rate or extent of myoblast proliferation.
2000819	regulation of nucleotide-excision repair	P	Any process that modulates the frequency, rate or extent of nucleotide-excision repair.
2000820	negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation	P	Any negative regulation of transcription from RNA polymerase II promoter that is involved in smooth muscle cell differentiation.
2000821	regulation of grooming behavior	P	Any process that modulates the frequency, rate or extent of grooming behavior.
2000822	regulation of behavioral fear response	P	Any process that modulates the frequency, rate or extent of behavioral fear response.
2000823	regulation of androgen receptor activity	P	Any process that modulates the frequency, rate or extent of androgen receptor activity.
2000824	negative regulation of androgen receptor activity	P	Any process that stops, prevents or reduces the frequency, rate or extent of androgen receptor activity.
2000825	positive regulation of androgen receptor activity	P	Any process that activates or increases the frequency, rate or extent of androgen receptor activity.
2000826	regulation of heart morphogenesis	P	Any process that modulates the frequency, rate or extent of heart morphogenesis.
2000827	mitochondrial RNA surveillance	P	The set of processes involved in identifying and degrading defective or aberrant RNAs that takes place in the mitochondrion.
2000828	regulation of parathyroid hormone secretion	P	Any process that modulates the frequency, rate or extent of parathyroid hormone secretion.
2000829	negative regulation of parathyroid hormone secretion	P	Any process that stops, prevents or reduces the frequency, rate or extent of parathyroid hormone secretion.
2000830	positive regulation of parathyroid hormone secretion	P	Any process that activates or increases the frequency, rate or extent of parathyroid hormone secretion.
2000831	regulation of steroid hormone secretion	P	Any process that modulates the frequency, rate or extent of steroid hormone secretion.
2000832	negative regulation of steroid hormone secretion	P	Any process that stops, prevents or reduces the frequency, rate or extent of steroid hormone secretion.
2000833	positive regulation of steroid hormone secretion	P	Any process that activates or increases the frequency, rate or extent of steroid hormone secretion.
2000834	regulation of androgen secretion	P	Any process that modulates the frequency, rate or extent of androgen secretion.
2000835	negative regulation of androgen secretion	P	Any process that stops, prevents or reduces the frequency, rate or extent of androgen secretion.
2000836	positive regulation of androgen secretion	P	Any process that activates or increases the frequency, rate or extent of androgen secretion.
2000837	regulation of androstenedione secretion	P	Any process that modulates the frequency, rate or extent of androstenedione secretion.
2000838	negative regulation of androstenedione secretion	P	Any process that stops, prevents or reduces the frequency, rate or extent of androstenedione secretion.
2000839	positive regulation of androstenedione secretion	P	Any process that activates or increases the frequency, rate or extent of androstenedione secretion.
2000840	regulation of dehydroepiandrosterone secretion	P	Any process that modulates the frequency, rate or extent of dehydroepiandrosterone secretion.
2000841	negative regulation of dehydroepiandrosterone secretion	P	Any process that stops, prevents or reduces the frequency, rate or extent of dehydroepiandrosterone secretion.
2000842	positive regulation of dehydroepiandrosterone secretion	P	Any process that activates or increases the frequency, rate or extent of dehydroepiandrosterone secretion.
2000843	regulation of testosterone secretion	P	Any process that modulates the frequency, rate or extent of testosterone secretion.
2000844	negative regulation of testosterone secretion	P	Any process that stops, prevents or reduces the frequency, rate or extent of testosterone secretion.
2000845	positive regulation of testosterone secretion	P	Any process that activates or increases the frequency, rate or extent of testosterone secretion.
2000846	regulation of corticosteroid hormone secretion	P	Any process that modulates the frequency, rate or extent of corticosteroid hormone secretion.
2000847	negative regulation of corticosteroid hormone secretion	P	Any process that stops, prevents or reduces the frequency, rate or extent of corticosteroid hormone secretion.
2000848	positive regulation of corticosteroid hormone secretion	P	Any process that activates or increases the frequency, rate or extent of corticosteroid hormone secretion.
2000849	regulation of glucocorticoid secretion	P	Any process that modulates the frequency, rate or extent of glucocorticoid secretion.
2000850	negative regulation of glucocorticoid secretion	P	Any process that stops, prevents or reduces the frequency, rate or extent of glucocorticoid secretion.
2000851	positive regulation of glucocorticoid secretion	P	Any process that activates or increases the frequency, rate or extent of glucocorticoid secretion.
2000852	regulation of corticosterone secretion	P	Any process that modulates the frequency, rate or extent of corticosterone secretion.
2000853	negative regulation of corticosterone secretion	P	Any process that stops, prevents or reduces the frequency, rate or extent of corticosterone secretion.
2000854	positive regulation of corticosterone secretion	P	Any process that activates or increases the frequency, rate or extent of corticosterone secretion.
2000855	regulation of mineralocorticoid secretion	P	Any process that modulates the frequency, rate or extent of mineralocorticoid secretion.
2000856	negative regulation of mineralocorticoid secretion	P	Any process that stops, prevents or reduces the frequency, rate or extent of mineralocorticoid secretion.
2000857	positive regulation of mineralocorticoid secretion	P	Any process that activates or increases the frequency, rate or extent of mineralocorticoid secretion.
2000858	regulation of aldosterone secretion	P	Any process that modulates the frequency, rate or extent of aldosterone secretion.
2000859	negative regulation of aldosterone secretion	P	Any process that stops, prevents or reduces the frequency, rate or extent of aldosterone secretion.
2000860	positive regulation of aldosterone secretion	P	Any process that activates or increases the frequency, rate or extent of aldosterone secretion.
2000861	regulation of estrogen secretion	P	Any process that modulates the frequency, rate or extent of estrogen secretion.
2000862	negative regulation of estrogen secretion	P	Any process that stops, prevents or reduces the frequency, rate or extent of estrogen secretion.
2000863	positive regulation of estrogen secretion	P	Any process that activates or increases the frequency, rate or extent of estrogen secretion.
2000864	regulation of estradiol secretion	P	Any process that modulates the frequency, rate or extent of estradiol secretion.
2000865	negative regulation of estradiol secretion	P	Any process that stops, prevents or reduces the frequency, rate or extent of estradiol secretion.
2000866	positive regulation of estradiol secretion	P	Any process that activates or increases the frequency, rate or extent of estradiol secretion.
2000867	regulation of estrone secretion	P	Any process that modulates the frequency, rate or extent of estrone secretion.
2000868	negative regulation of estrone secretion	P	Any process that stops, prevents or reduces the frequency, rate or extent of estrone secretion.
2000869	positive regulation of estrone secretion	P	Any process that activates or increases the frequency, rate or extent of estrone secretion.
2000870	regulation of progesterone secretion	P	Any process that modulates the frequency, rate or extent of progesterone secretion.
2000871	negative regulation of progesterone secretion	P	Any process that stops, prevents or reduces the frequency, rate or extent of progesterone secretion.
2000872	positive regulation of progesterone secretion	P	Any process that activates or increases the frequency, rate or extent of progesterone secretion.
2000873	regulation of histone H4 acetylation involved in response to DNA damage stimulus	P	Any process that modulates the frequency, rate or extent of histone H4 acetylation involved in response to DNA damage stimulus.
2000874	regulation of glyoxylate cycle	P	Any process that modulates the frequency, rate or extent of glyoxylate cycle.
2000875	negative regulation of glyoxylate cycle	P	Any process that stops, prevents or reduces the frequency, rate or extent of glyoxylate cycle.
2000876	positive regulation of glyoxylate cycle	P	Any process that activates or increases the frequency, rate or extent of glyoxylate cycle.
2000877	negative regulation of oligopeptide transport	P	Any process that stops, prevents or reduces the frequency, rate or extent of oligopeptide transport.
2000878	positive regulation of oligopeptide transport	P	Any process that activates or increases the frequency, rate or extent of oligopeptide transport.
2000879	negative regulation of dipeptide transport	P	Any process that stops, prevents or reduces the frequency, rate or extent of dipeptide transport.
2000880	positive regulation of dipeptide transport	P	Any process that activates or increases the frequency, rate or extent of dipeptide transport.
2000881	regulation of starch catabolic process	P	Any process that modulates the frequency, rate or extent of starch catabolic process.
2000882	negative regulation of starch catabolic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of starch catabolic process.
2000883	positive regulation of starch catabolic process	P	Any process that activates or increases the frequency, rate or extent of starch catabolic process.
2000884	glucomannan catabolic process	P	The chemical reactions and pathways resulting in the breakdown of a glucomannan.
2000885	galactoglucomannan catabolic process	P	The chemical reactions and pathways resulting in the breakdown of a galactoglucomannan.
2000886	glucuronoxylan catabolic process	P	The chemical reactions and pathways resulting in the breakdown of a glucuronoxylan.
2000887	glucuronoarabinoxylan catabolic process	P	The chemical reactions and pathways resulting in the breakdown of a glucuronoarabinoxylan.
2000888	arabinoxylan-containing compound catabolic process	P	The chemical reactions and pathways resulting in the breakdown of an arabinoxylan.
2000889	cellodextrin metabolic process	P	The chemical reactions and pathways involving a cellodextrin.
2000890	cellodextrin catabolic process	P	The chemical reactions and pathways resulting in the breakdown of a cellodextrin.
2000891	cellobiose metabolic process	P	The chemical reactions and pathways involving a cellobiose.
2000892	cellobiose catabolic process	P	The chemical reactions and pathways resulting in the breakdown of a cellobiose.
2000893	cellotriose metabolic process	P	The chemical reactions and pathways involving a cellotriose.
2000894	cellotriose catabolic process	P	The chemical reactions and pathways resulting in the breakdown of a cellotriose.
2000895	hemicellulose catabolic process	P	The chemical reactions and pathways resulting in the breakdown of a hemicellulose.
2000896	amylopectin metabolic process	P	The chemical reactions and pathways involving an amylopectin.
2000897	amylopectin catabolic process	P	The chemical reactions and pathways resulting in the breakdown of an amylopectin.
2000898	regulation of glucomannan catabolic process	P	Any process that modulates the frequency, rate or extent of glucomannan catabolic process.
2000899	xyloglucan catabolic process	P	The chemical reactions and pathways resulting in the breakdown of a xyloglucan.
2000900	cyclodextrin metabolic process	P	The chemical reactions and pathways involving a cyclodextrin.
2000901	cyclodextrin catabolic process	P	The chemical reactions and pathways resulting in the breakdown of a cyclodextrin.
2000902	cellooligosaccharide metabolic process	P	The chemical reactions and pathways involving a cellooligosaccharide.
2000903	cellooligosaccharide catabolic process	P	The chemical reactions and pathways resulting in the breakdown of a cellooligosaccharide.
2000904	regulation of starch metabolic process	P	Any process that modulates the frequency, rate or extent of starch metabolic process.
2000905	negative regulation of starch metabolic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of starch metabolic process.
2000906	positive regulation of starch metabolic process	P	Any process that activates or increases the frequency, rate or extent of starch metabolic process.
2000907	negative regulation of glucomannan catabolic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of glucomannan catabolic process.
2000908	positive regulation of glucomannan catabolic process	P	Any process that activates or increases the frequency, rate or extent of glucomannan catabolic process.
2000909	regulation of sterol import	P	Any process that modulates the frequency, rate or extent of sterol import.
2000910	negative regulation of sterol import	P	Any process that stops, prevents or reduces the frequency, rate or extent of sterol import.
2000911	positive regulation of sterol import	P	Any process that activates or increases the frequency, rate or extent of sterol import.
2000912	regulation of galactoglucomannan catabolic process	P	Any process that modulates the frequency, rate or extent of galactoglucomannan catabolic process.
2000913	negative regulation of galactoglucomannan catabolic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of galactoglucomannan catabolic process.
2000914	positive regulation of galactoglucomannan catabolic process	P	Any process that activates or increases the frequency, rate or extent of galactoglucomannan catabolic process.
2000915	regulation of glucuronoxylan catabolic process	P	Any process that modulates the frequency, rate or extent of glucuronoxylan catabolic process.
2000916	negative regulation of glucuronoxylan catabolic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of glucuronoxylan catabolic process.
2000917	positive regulation of glucuronoxylan catabolic process	P	Any process that activates or increases the frequency, rate or extent of glucuronoxylan catabolic process.
2000918	regulation of glucuronoarabinoxylan catabolic process	P	Any process that modulates the frequency, rate or extent of glucuronoarabinoxylan catabolic process.
2000919	negative regulation of glucuronoarabinoxylan catabolic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of glucuronoarabinoxylan catabolic process.
2000920	positive regulation of glucuronoarabinoxylan catabolic process	P	Any process that activates or increases the frequency, rate or extent of glucuronoarabinoxylan catabolic process.
2000921	regulation of arabinoxylan-containing compound catabolic process	P	Any process that modulates the frequency, rate or extent of arabinoxylan-containing compound catabolic process.
2000922	negative regulation of arabinoxylan-containing compound catabolic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of arabinoxylan-containing compound catabolic process.
2000923	positive regulation of arabinoxylan-containing compound catabolic process	P	Any process that activates or increases the frequency, rate or extent of arabinoxylan-containing compound catabolic process.
2000924	regulation of cellodextrin metabolic process	P	Any process that modulates the frequency, rate or extent of cellodextrin metabolic process.
2000925	negative regulation of cellodextrin metabolic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of cellodextrin metabolic process.
2000926	positive regulation of cellodextrin metabolic process	P	Any process that activates or increases the frequency, rate or extent of cellodextrin metabolic process.
2000927	regulation of cellodextrin catabolic process	P	Any process that modulates the frequency, rate or extent of cellodextrin catabolic process.
2000928	negative regulation of cellodextrin catabolic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of cellodextrin catabolic process.
2000929	positive regulation of cellodextrin catabolic process	P	Any process that activates or increases the frequency, rate or extent of cellodextrin catabolic process.
2000930	regulation of cellobiose metabolic process	P	Any process that modulates the frequency, rate or extent of cellobiose metabolic process.
2000931	negative regulation of cellobiose metabolic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of cellobiose metabolic process.
2000932	positive regulation of cellobiose metabolic process	P	Any process that activates or increases the frequency, rate or extent of cellobiose metabolic process.
2000933	regulation of cellotriose metabolic process	P	Any process that modulates the frequency, rate or extent of cellotriose metabolic process.
2000934	negative regulation of cellotriose metabolic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of cellotriose metabolic process.
2000935	positive regulation of cellotriose metabolic process	P	Any process that activates or increases the frequency, rate or extent of cellotriose metabolic process.
2000936	regulation of cellotriose catabolic process	P	Any process that modulates the frequency, rate or extent of cellotriose catabolic process.
2000937	negative regulation of cellotriose catabolic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of cellotriose catabolic process.
2000938	positive regulation of cellotriose catabolic process	P	Any process that activates or increases the frequency, rate or extent of cellotriose catabolic process.
2000939	regulation of plant-type cell wall cellulose catabolic process	P	Any process that modulates the frequency, rate or extent of plant-type cell wall cellulose catabolic process.
2000940	negative regulation of plant-type cell wall cellulose catabolic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of plant-type cell wall cellulose catabolic process.
2000941	positive regulation of plant-type cell wall cellulose catabolic process	P	Any process that activates or increases the frequency, rate or extent of plant-type cell wall cellulose catabolic process.
2000942	regulation of amylopectin metabolic process	P	Any process that modulates the frequency, rate or extent of amylopectin metabolic process.
2000943	negative regulation of amylopectin metabolic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of amylopectin metabolic process.
2000944	positive regulation of amylopectin metabolic process	P	Any process that activates or increases the frequency, rate or extent of amylopectin metabolic process.
2000945	regulation of amylopectin catabolic process	P	Any process that modulates the frequency, rate or extent of amylopectin catabolic process.
2000946	negative regulation of amylopectin catabolic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of amylopectin catabolic process.
2000947	positive regulation of amylopectin catabolic process	P	Any process that activates or increases the frequency, rate or extent of amylopectin catabolic process.
2000948	regulation of xyloglucan metabolic process	P	Any process that modulates the frequency, rate or extent of xyloglucan metabolic process.
2000949	negative regulation of xyloglucan metabolic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of xyloglucan metabolic process.
2000950	positive regulation of xyloglucan metabolic process	P	Any process that activates or increases the frequency, rate or extent of xyloglucan metabolic process.
2000951	regulation of xyloglucan catabolic process	P	Any process that modulates the frequency, rate or extent of xyloglucan catabolic process.
2000952	negative regulation of xyloglucan catabolic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of xyloglucan catabolic process.
2000953	positive regulation of xyloglucan catabolic process	P	Any process that activates or increases the frequency, rate or extent of xyloglucan catabolic process.
2000954	regulation of cyclodextrin metabolic process	P	Any process that modulates the frequency, rate or extent of cyclodextrin metabolic process.
2000955	negative regulation of cyclodextrin metabolic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of cyclodextrin metabolic process.
2000956	positive regulation of cyclodextrin metabolic process	P	Any process that activates or increases the frequency, rate or extent of cyclodextrin metabolic process.
2000957	regulation of cyclodextrin catabolic process	P	Any process that modulates the frequency, rate or extent of cyclodextrin catabolic process.
2000958	negative regulation of cyclodextrin catabolic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of cyclodextrin catabolic process.
2000959	positive regulation of cyclodextrin catabolic process	P	Any process that activates or increases the frequency, rate or extent of cyclodextrin catabolic process.
2000960	regulation of cellooligosaccharide metabolic process	P	Any process that modulates the frequency, rate or extent of cellooligosaccharide metabolic process.
2000961	negative regulation of cellooligosaccharide metabolic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of cellooligosaccharide metabolic process.
2000962	positive regulation of cellooligosaccharide metabolic process	P	Any process that activates or increases the frequency, rate or extent of cellooligosaccharide metabolic process.
2000963	regulation of cellooligosaccharide catabolic process	P	Any process that modulates the frequency, rate or extent of cellooligosaccharide catabolic process.
2000964	negative regulation of cellooligosaccharide catabolic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of cellooligosaccharide catabolic process.
2000965	positive regulation of cellooligosaccharide catabolic process	P	Any process that activates or increases the frequency, rate or extent of cellooligosaccharide catabolic process.
2000966	regulation of cell wall polysaccharide catabolic process	P	Any process that modulates the frequency, rate or extent of cell wall polysaccharide catabolic process.
2000967	negative regulation of cell wall polysaccharide catabolic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of cell wall polysaccharide catabolic process.
2000968	positive regulation of cell wall polysaccharide catabolic process	P	Any process that activates or increases the frequency, rate or extent of cell wall polysaccharide catabolic process.
2000969	positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity	P	Any process that activates or increases the frequency, rate or extent of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity.
2000970	regulation of detection of glucose	P	Any process that modulates the frequency, rate or extent of detection of glucose.
2000971	negative regulation of detection of glucose	P	Any process that stops, prevents or reduces the frequency, rate or extent of detection of glucose.
2000972	positive regulation of detection of glucose	P	Any process that activates or increases the frequency, rate or extent of detection of glucose.
2000973	regulation of pro-B cell differentiation	P	Any process that modulates the frequency, rate or extent of pro-B cell differentiation.
2000974	negative regulation of pro-B cell differentiation	P	Any process that stops, prevents or reduces the frequency, rate or extent of pro-B cell differentiation.
2000975	positive regulation of pro-B cell differentiation	P	Any process that activates or increases the frequency, rate or extent of pro-B cell differentiation.
2000977	regulation of forebrain neuron differentiation	P	Any process that modulates the frequency, rate or extent of forebrain neuron differentiation.
2000978	negative regulation of forebrain neuron differentiation	P	Any process that stops, prevents or reduces the frequency, rate or extent of forebrain neuron differentiation.
2000979	positive regulation of forebrain neuron differentiation	P	Any process that activates or increases the frequency, rate or extent of forebrain neuron differentiation.
2000980	regulation of inner ear receptor cell differentiation	P	Any process that modulates the frequency, rate or extent of inner ear receptor cell differentiation.
2000981	negative regulation of inner ear receptor cell differentiation	P	Any process that stops, prevents or reduces the frequency, rate or extent of inner ear receptor cell differentiation.
2000982	positive regulation of inner ear receptor cell differentiation	P	Any process that activates or increases the frequency, rate or extent of inner ear receptor cell differentiation.
2000983	regulation of ATP citrate synthase activity	P	Any process that modulates the frequency, rate or extent of ATP citrate synthase activity.
2000984	negative regulation of ATP citrate synthase activity	P	Any process that stops, prevents or reduces the frequency, rate or extent of ATP citrate synthase activity.
2000985	positive regulation of ATP citrate synthase activity	P	Any process that activates or increases the frequency, rate or extent of ATP citrate synthase activity.
2000986	negative regulation of behavioral fear response	P	Any process that stops, prevents or reduces the frequency, rate or extent of behavioral fear response.
2000987	positive regulation of behavioral fear response	P	Any process that activates or increases the frequency, rate or extent of behavioral fear response.
2000988	regulation of hemicellulose catabolic process	P	Any process that modulates the frequency, rate or extent of hemicellulose catabolic process.
2000989	negative regulation of hemicellulose catabolic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of hemicellulose catabolic process.
2000990	positive regulation of hemicellulose catabolic process	P	Any process that activates or increases the frequency, rate or extent of hemicellulose catabolic process.
2000991	regulation of galactomannan catabolic process	P	Any process that modulates the frequency, rate or extent of galactomannan catabolic process.
2000992	negative regulation of galactomannan catabolic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of galactomannan catabolic process.
2000993	positive regulation of galactomannan catabolic process	P	Any process that activates or increases the frequency, rate or extent of galactomannan catabolic process.
2000994	regulation of mannan catabolic process	P	Any process that modulates the frequency, rate or extent of mannan catabolic process.
2000995	negative regulation of mannan catabolic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of mannan catabolic process.
2000996	positive regulation of mannan catabolic process	P	Any process that activates or increases the frequency, rate or extent of mannan catabolic process.
2000997	regulation of cellulose catabolic process	P	Any process that modulates the frequency, rate or extent of cellulose catabolic process.
2000998	negative regulation of cellulose catabolic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of cellulose catabolic process.
2000999	positive regulation of cellulose catabolic process	P	Any process that activates or increases the frequency, rate or extent of cellulose catabolic process.
2001000	regulation of xylan catabolic process	P	Any process that modulates the frequency, rate or extent of xylan catabolic process.
2001001	negative regulation of xylan catabolic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of xylan catabolic process.
2001002	positive regulation of xylan catabolic process	P	Any process that activates or increases the frequency, rate or extent of xylan catabolic process.
2001003	regulation of pectin catabolic process	P	Any process that modulates the frequency, rate or extent of pectin catabolic process.
2001004	negative regulation of pectin catabolic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of pectin catabolic process.
2001005	positive regulation of pectin catabolic process	P	Any process that activates or increases the frequency, rate or extent of pectin catabolic process.
2001006	regulation of cellulose biosynthetic process	P	Any process that modulates the frequency, rate or extent of cellulose biosynthetic process.
2001007	negative regulation of cellulose biosynthetic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of cellulose biosynthetic process.
2001008	positive regulation of cellulose biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of cellulose biosynthetic process.
2001009	regulation of plant-type cell wall cellulose biosynthetic process	P	Any process that modulates the frequency, rate or extent of plant-type cell wall cellulose biosynthetic process.
2001010	negative regulation of plant-type cell wall cellulose biosynthetic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of plant-type cell wall cellulose biosynthetic process.
2001011	positive regulation of plant-type cell wall cellulose biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of plant-type cell wall cellulose biosynthetic process.
2001012	mesenchymal cell differentiation involved in renal system development	P	The process in which relatively unspecialized cells acquire specialized structural and/or functional features that characterize the mesenchymal cells of the renal system as it progresses from its formation to the mature state.
2001013	epithelial cell proliferation involved in renal tubule morphogenesis	P	Any epithelial cell proliferation that is involved in renal tubule morphogenesis.
2001014	regulation of skeletal muscle cell differentiation	P	Any process that modulates the frequency, rate or extent of skeletal muscle cell differentiation.
2001015	negative regulation of skeletal muscle cell differentiation	P	Any process that stops, prevents or reduces the frequency, rate or extent of skeletal muscle cell differentiation.
2001016	positive regulation of skeletal muscle cell differentiation	P	Any process that activates or increases the frequency, rate or extent of skeletal muscle cell differentiation.
2001017	regulation of retrograde axon cargo transport	P	Any process that modulates the frequency, rate or extent of retrograde axon cargo transport.
2001018	negative regulation of retrograde axon cargo transport	P	Any process that stops, prevents or reduces the frequency, rate or extent of retrograde axon cargo transport.
2001019	positive regulation of retrograde axon cargo transport	P	Any process that activates or increases the frequency, rate or extent of retrograde axon cargo transport.
2001020	regulation of response to DNA damage stimulus	P	Any process that modulates the frequency, rate or extent of response to DNA damage stimulus.
2001021	negative regulation of response to DNA damage stimulus	P	Any process that stops, prevents or reduces the frequency, rate or extent of response to DNA damage stimulus.
2001022	positive regulation of response to DNA damage stimulus	P	Any process that activates or increases the frequency, rate or extent of response to DNA damage stimulus.
2001023	regulation of response to drug	P	Any process that modulates the frequency, rate or extent of response to drug.
2001024	negative regulation of response to drug	P	Any process that stops, prevents or reduces the frequency, rate or extent of response to drug.
2001025	positive regulation of response to drug	P	Any process that activates or increases the frequency, rate or extent of response to drug.
2001026	regulation of endothelial cell chemotaxis	P	Any process that modulates the frequency, rate or extent of endothelial cell chemotaxis.
2001027	negative regulation of endothelial cell chemotaxis	P	Any process that stops, prevents or reduces the frequency, rate or extent of endothelial cell chemotaxis.
2001028	positive regulation of endothelial cell chemotaxis	P	Any process that activates or increases the frequency, rate or extent of endothelial cell chemotaxis.
2001029	regulation of cellular glucuronidation	P	Any process that modulates the frequency, rate or extent of cellular glucuronidation.
2001030	negative regulation of cellular glucuronidation	P	Any process that stops, prevents or reduces the frequency, rate or extent of cellular glucuronidation.
2001031	positive regulation of cellular glucuronidation	P	Any process that activates or increases the frequency, rate or extent of cellular glucuronidation.
2001032	regulation of double-strand break repair via nonhomologous end joining	P	Any process that modulates the frequency, rate or extent of double-strand break repair via nonhomologous end joining.
2001033	negative regulation of double-strand break repair via nonhomologous end joining	P	Any process that stops, prevents or reduces the frequency, rate or extent of double-strand break repair via nonhomologous end joining.
2001034	positive regulation of double-strand break repair via nonhomologous end joining	P	Any process that activates or increases the frequency, rate or extent of double-strand break repair via nonhomologous end joining.
2001035	regulation of tongue muscle cell differentiation	P	Any process that modulates the frequency, rate or extent of tongue muscle cell differentiation.
2001036	negative regulation of tongue muscle cell differentiation	P	Any process that stops, prevents or reduces the frequency, rate or extent of tongue muscle cell differentiation.
2001037	positive regulation of tongue muscle cell differentiation	P	Any process that activates or increases the frequency, rate or extent of tongue muscle cell differentiation.
2001038	regulation of cellular response to drug	P	Any process that modulates the frequency, rate or extent of cellular response to drug.
2001039	negative regulation of cellular response to drug	P	Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to drug.
2001040	positive regulation of cellular response to drug	P	Any process that activates or increases the frequency, rate or extent of cellular response to drug.
2001042	negative regulation of cell separation after cytokinesis	P	Any process that stops, prevents or reduces the frequency, rate or extent of cell separation involved in cell cycle cytokinesis.
2001043	positive regulation of cell separation after cytokinesis	P	Any process that activates or increases the frequency, rate or extent of cell separation involved after cell cycle cytokinesis.
2001044	regulation of integrin-mediated signaling pathway	P	Any process that modulates the frequency, rate or extent of integrin-mediated signaling pathway.
2001045	negative regulation of integrin-mediated signaling pathway	P	Any process that stops, prevents or reduces the frequency, rate or extent of integrin-mediated signaling pathway.
2001046	positive regulation of integrin-mediated signaling pathway	P	Any process that activates or increases the frequency, rate or extent of integrin-mediated signaling pathway.
2001049	regulation of tendon cell differentiation	P	Any process that modulates the frequency, rate or extent of tendon cell differentiation.
2001050	negative regulation of tendon cell differentiation	P	Any process that stops, prevents or reduces the frequency, rate or extent of tendon cell differentiation.
2001051	positive regulation of tendon cell differentiation	P	Any process that activates or increases the frequency, rate or extent of tendon cell differentiation.
2001053	regulation of mesenchymal cell apoptotic process	P	Any process that modulates the frequency, rate or extent of mesenchymal cell apoptotic process.
2001054	negative regulation of mesenchymal cell apoptotic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of mesenchymal cell apoptotic process.
2001055	positive regulation of mesenchymal cell apoptotic process	P	Any process that activates or increases the frequency, rate or extent of mesenchymal cell apoptotic process.
2001056	positive regulation of cysteine-type endopeptidase activity	P	Any process that activates or increases the frequency, rate or extent of cysteine-type endopeptidase activity.
2001057	reactive nitrogen species metabolic process	P	The chemical reactions and pathways involving a reactive nitrogen species.
2001058	D-tagatose 6-phosphate metabolic process	P	The chemical reactions and pathways involving a D-tagatose 6-phosphate.
2001059	D-tagatose 6-phosphate catabolic process	P	The chemical reactions and pathways resulting in the breakdown of a D-tagatose 6-phosphate.
2001060	D-glycero-D-manno-heptose 7-phosphate metabolic process	P	The chemical reactions and pathways involving a D-glycero-D-manno-heptose 7-phosphate.
2001061	D-glycero-D-manno-heptose 7-phosphate biosynthetic process	P	The chemical reactions and pathways resulting in the formation of a D-glycero-D-manno-heptose 7-phosphate.
2001062	xylan binding	F	Interacting selectively and non-covalently with xylan.
2001063	glucomannan binding	F	Interacting selectively and non-covalently with glucomannan.
2001064	cellooligosaccharide binding	F	Interacting selectively and non-covalently with cellooligosaccharide.
2001065	mannan binding	F	Interacting selectively and non-covalently with mannan.
2001066	amylopectin binding	F	Interacting selectively and non-covalently with amylopectin.
2001067	pullulan binding	F	Interacting selectively and non-covalently with pullulan.
2001068	arabinoxylan binding	F	Interacting selectively and non-covalently with arabinoxylan.
2001069	glycogen binding	F	Interacting selectively and non-covalently with glycogen.
2001070	starch binding	F	Interacting selectively and non-covalently with starch.
2001071	maltoheptaose binding	F	Interacting selectively and non-covalently with maltoheptaose.
2001072	galactomannan binding	F	Interacting selectively and non-covalently with galactomannan.
2001073	cyclodextrin binding	F	Interacting selectively and non-covalently with cyclodextrin.
2001074	regulation of metanephric ureteric bud development	P	Any process that modulates the frequency, rate or extent of metanephric ureteric bud development.
2001075	negative regulation of metanephric ureteric bud development	P	Any process that stops, prevents or reduces the frequency, rate or extent of metanephric ureteric bud development.
2001076	positive regulation of metanephric ureteric bud development	P	Any process that activates or increases the frequency, rate or extent of metanephric ureteric bud development.
2001077	(1->3),(1->4)-beta-glucan binding	F	Interacting selectively and non-covalently with (1->3),(1->4)-beta-glucan.
2001078	(1->6)-beta-D-glucan binding	F	Interacting selectively and non-covalently with (1->6)-beta-D-glucan.
2001079	beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-D-Glc binding	F	Interacting selectively and non-covalently with beta-D-Gal-(1->4)-beta-D-GlcNAc-(1->3)-beta-D-Gal-(1->4)-D-Glc.
2001080	chitosan binding	F	Interacting selectively and non-covalently with chitosan.
2001081	(1->4)-beta-D-galactan binding	F	Interacting selectively and non-covalently with (1->4)-beta-D-galactan.
2001082	inulin binding	F	Interacting selectively and non-covalently with inulin.
2001083	alpha-D-glucan binding	F	Interacting selectively and non-covalently with alpha-D-glucan.
2001084	L-arabinofuranose binding	F	Interacting selectively and non-covalently with L-arabinofuranose.
2001085	arabinogalactan binding	F	Interacting selectively and non-covalently with arabinogalactan.
2001086	laminarabiose transport	P	The directed movement of a laminarabioseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
2001087	sophorose transport	P	The directed movement of a sophoroseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
2001088	trisaccharide transport	P	The directed movement of a trisaccharideacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
2001089	maltotriose transport	P	The directed movement of a maltotrioseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
2001090	maltotriulose transport	P	The directed movement of a maltotriuloseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
2001091	nigerotriose transport	P	The directed movement of a nigerotrioseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
2001092	arabinotriose transport	P	The directed movement of an arabinotrioseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
2001093	galactotriose transport	P	The directed movement of a galactotrioseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
2001094	xylotriose transport	P	The directed movement of a xylotrioseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
2001095	mannotriose transport	P	The directed movement of a mannotrioseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
2001096	cellotriose transport	P	The directed movement of a cellotrioseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
2001097	laminaritriose transport	P	The directed movement of a laminaritrioseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
2001098	tetrasaccharide transport	P	The directed movement of a tetrasaccharideacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
2001099	maltotetraose transport	P	The directed movement of a maltotetraoseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
2001100	pentasaccharide transport	P	The directed movement of a pentasaccharideacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
2001101	maltopentaose transport	P	The directed movement of a maltopentaoseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
2001102	hexasaccharide transport	P	The directed movement of a hexasaccharideacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
2001103	maltohexaose transport	P	The directed movement of a maltohexaoseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
2001104	heptasaccharide transport	P	The directed movement of a heptasaccharideacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
2001105	maltoheptaose transport	P	The directed movement of a maltoheptaoseacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
2001106	regulation of Rho guanyl-nucleotide exchange factor activity	P	Any process that modulates the frequency, rate or extent of Rho guanyl-nucleotide exchange factor activity.
2001107	negative regulation of Rho guanyl-nucleotide exchange factor activity	P	Any process that stops, prevents or reduces the frequency, rate or extent of Rho guanyl-nucleotide exchange factor activity.
2001108	positive regulation of Rho guanyl-nucleotide exchange factor activity	P	Any process that activates or increases the frequency, rate or extent of Rho guanyl-nucleotide exchange factor activity.
2001109	regulation of lens epithelial cell proliferation	P	Any process that modulates the frequency, rate or extent of lens epithelial cell proliferation.
2001110	negative regulation of lens epithelial cell proliferation	P	Any process that stops, prevents or reduces the frequency, rate or extent of lens epithelial cell proliferation.
2001111	positive regulation of lens epithelial cell proliferation	P	Any process that activates or increases the frequency, rate or extent of lens epithelial cell proliferation.
2001112	regulation of cellular response to hepatocyte growth factor stimulus	P	Any process that modulates the frequency, rate or extent of cellular response to hepatocyte growth factor stimulus.
2001113	negative regulation of cellular response to hepatocyte growth factor stimulus	P	Any process that stops, prevents or reduces the frequency, rate or extent of cellular response to hepatocyte growth factor stimulus.
2001114	positive regulation of cellular response to hepatocyte growth factor stimulus	P	Any process that activates or increases the frequency, rate or extent of cellular response to hepatocyte growth factor stimulus.
2001115	methanopterin-containing compound metabolic process	P	The chemical reactions and pathways involving a methanopterin.
2001116	methanopterin-containing compound biosynthetic process	P	The chemical reactions and pathways resulting in the formation of a methanopterin.
2001117	tetrahydromethanopterin metabolic process	P	The chemical reactions and pathways involving a tetrahydromethanopterin.
2001118	tetrahydromethanopterin biosynthetic process	P	The chemical reactions and pathways resulting in the formation of a tetrahydromethanopterin.
2001119	methanofuran metabolic process	P	The chemical reactions and pathways involving a methanofuran.
2001120	methanofuran biosynthetic process	P	The chemical reactions and pathways resulting in the formation of a methanofuran.
2001121	coenzyme gamma-F420-2 biosynthetic process	P	The chemical reactions and pathways resulting in the formation of a coenzyme gamma-F420-2.
2001122	maltoheptaose metabolic process	P	The chemical reactions and pathways involving a maltoheptaose.
2001123	maltoheptaose catabolic process	P	The chemical reactions and pathways resulting in the breakdown of a maltoheptaose.
2001124	regulation of translational frameshifting	P	Any process that modulates the frequency, rate or extent of translational frameshifting.
2001125	negative regulation of translational frameshifting	P	Any process that stops, prevents or reduces the frequency, rate or extent of translational frameshifting.
2001126	positive regulation of translational frameshifting	P	Any process that activates or increases the frequency, rate or extent of translational frameshifting.
2001127	methane biosynthetic process from formic acid	P	The chemical reactions and pathways resulting in the formation of a methane from a formic acid.
2001128	methane biosynthetic process from methylamine	P	The chemical reactions and pathways resulting in the formation of a methane from a methylamine.
2001129	methane biosynthetic process from dimethylamine	P	The chemical reactions and pathways resulting in the formation of a methane from a dimethylamine.
2001130	methane biosynthetic process from trimethylamine	P	The chemical reactions and pathways resulting in the formation of a methane from a trimethylamine.
2001131	methane biosynthetic process from dimethyl sulfide	P	The chemical reactions and pathways resulting in the formation of a methane from a dimethyl sulfide.
2001132	methane biosynthetic process from 3-(methylthio)propionic acid	P	The chemical reactions and pathways resulting in the formation of a methane from a 3-(methylthio)propionic acid.
2001133	methane biosynthetic process from methanethiol	P	The chemical reactions and pathways resulting in the formation of a methane from a methanethiol.
2001134	methane biosynthetic process from carbon monoxide	P	The chemical reactions and pathways resulting in the formation of a methane from a carbon monoxide.
2001135	regulation of endocytic recycling	P	Any process that modulates the frequency, rate or extent of endocytic recycling.
2001136	negative regulation of endocytic recycling	P	Any process that stops, prevents or reduces the frequency, rate or extent of endocytic recycling.
2001137	positive regulation of endocytic recycling	P	Any process that activates or increases the frequency, rate or extent of endocytic recycling.
2001138	regulation of phospholipid transport	P	Any process that modulates the frequency, rate or extent of phospholipid transport.
2001139	negative regulation of phospholipid transport	P	Any process that stops, prevents or reduces the frequency, rate or extent of phospholipid transport.
2001140	positive regulation of phospholipid transport	P	Any process that activates or increases the frequency, rate or extent of phospholipid transport.
2001141	regulation of RNA biosynthetic process	P	Any process that modulates the frequency, rate or extent of RNA biosynthetic process.
2001142	nicotinate transport	P	The directed movement of a nicotinateacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
2001143	N-methylnicotinate transport	P	The directed movement of a N-methylnicotinateacetate into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
2001144	regulation of phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity	P	Any process that modulates the frequency, rate or extent of phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity.
2001145	negative regulation of phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity	P	Any process that stops, prevents or reduces the frequency, rate or extent of phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity.
2001146	positive regulation of phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity	P	Any process that activates or increases the frequency, rate or extent of phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity.
2001147	camalexin binding	F	Interacting selectively and non-covalently with camalexin.
2001148	regulation of dipeptide transmembrane transport	P	Any process that modulates the frequency, rate or extent of dipeptide transmembrane transport.
2001149	negative regulation of dipeptide transmembrane transport	P	Any process that stops, prevents or reduces the frequency, rate or extent of dipeptide transmembrane transport.
2001150	positive regulation of dipeptide transmembrane transport	P	Any process that activates or increases the frequency, rate or extent of dipeptide transmembrane transport.
2001151	regulation of renal water transport	P	Any process that modulates the frequency, rate or extent of renal water transport.
2001152	negative regulation of renal water transport	P	Any process that stops, prevents or reduces the frequency, rate or extent of renal water transport.
2001153	positive regulation of renal water transport	P	Any process that activates or increases the frequency, rate or extent of renal water transport.
2001154	regulation of glycolytic fermentation to ethanol	P	Any process that modulates the frequency, rate or extent of glucose catabolic process to ethanol.
2001155	negative regulation of glycolytic fermentation to ethanol	P	Any process that stops, prevents or reduces the frequency, rate or extent of glucose catabolic process to ethanol.
2001156	regulation of proline catabolic process to glutamate	P	Any process that modulates the frequency, rate or extent of proline catabolic process to glutamate.
2001157	negative regulation of proline catabolic process to glutamate	P	Any process that stops, prevents or reduces the frequency, rate or extent of proline catabolic process to glutamate.
2001158	positive regulation of proline catabolic process to glutamate	P	Any process that activates or increases the frequency, rate or extent of proline catabolic process to glutamate.
2001159	regulation of CVT pathway	P	Any process that modulates the frequency, rate or extent of CVT pathway.
2001160	regulation of histone H3-K79 methylation	P	Any process that modulates the frequency, rate or extent of histone H3-K79 methylation.
2001161	negative regulation of histone H3-K79 methylation	P	Any process that stops, prevents or reduces the frequency, rate or extent of histone H3-K79 methylation.
2001162	positive regulation of histone H3-K79 methylation	P	Any process that activates or increases the frequency, rate or extent of histone H3-K79 methylation.
2001163	regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues	P	Any process that modulates the frequency, rate or extent of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues.
2001164	negative regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues	P	Any process that stops, prevents or reduces the frequency, rate or extent of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues.
2001165	positive regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues	P	Any process that activates or increases the frequency, rate or extent of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues.
2001166	regulation of histone H2B ubiquitination	P	Any process that modulates the frequency, rate or extent of histone H2B ubiquitination.
2001167	negative regulation of histone H2B ubiquitination	P	Any process that stops, prevents or reduces the frequency, rate or extent of histone H2B ubiquitination.
2001168	positive regulation of histone H2B ubiquitination	P	Any process that activates or increases the frequency, rate or extent of histone H2B ubiquitination.
2001169	regulation of ATP biosynthetic process	P	Any process that modulates the frequency, rate or extent of ATP biosynthetic process.
2001170	negative regulation of ATP biosynthetic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of ATP biosynthetic process.
2001171	positive regulation of ATP biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of ATP biosynthetic process.
2001172	positive regulation of glycolytic fermentation to ethanol	P	Any process that activates or increases the frequency, rate or extent of glucose catabolic process to ethanol.
2001173	regulation of histone H2B conserved C-terminal lysine ubiquitination	P	Any process that modulates the frequency, rate or extent of histone H2B conserved C-terminal lysine ubiquitination.
2001174	negative regulation of histone H2B conserved C-terminal lysine ubiquitination	P	Any process that stops, prevents or reduces the frequency, rate or extent of histone H2B conserved C-terminal lysine ubiquitination.
2001175	positive regulation of histone H2B conserved C-terminal lysine ubiquitination	P	Any process that activates or increases the frequency, rate or extent of histone H2B conserved C-terminal lysine ubiquitination.
2001176	regulation of mediator complex assembly	P	Any process that modulates the frequency, rate or extent of mediator complex assembly.
2001177	negative regulation of mediator complex assembly	P	Any process that stops, prevents or reduces the frequency, rate or extent of mediator complex assembly.
2001178	positive regulation of mediator complex assembly	P	Any process that activates or increases the frequency, rate or extent of mediator complex assembly.
2001179	regulation of interleukin-10 secretion	P	Any process that modulates the frequency, rate or extent of interleukin-10 secretion.
2001180	negative regulation of interleukin-10 secretion	P	Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-10 secretion.
2001181	positive regulation of interleukin-10 secretion	P	Any process that activates or increases the frequency, rate or extent of interleukin-10 secretion.
2001182	regulation of interleukin-12 secretion	P	Any process that modulates the frequency, rate or extent of interleukin-12 secretion.
2001183	negative regulation of interleukin-12 secretion	P	Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-12 secretion.
2001184	positive regulation of interleukin-12 secretion	P	Any process that activates or increases the frequency, rate or extent of interleukin-12 secretion.
2001185	regulation of CD8-positive, alpha-beta T cell activation	P	Any process that modulates the frequency, rate or extent of CD8-positive, alpha-beta T cell activation.
2001186	negative regulation of CD8-positive, alpha-beta T cell activation	P	Any process that stops, prevents or reduces the frequency, rate or extent of CD8-positive, alpha-beta T cell activation.
2001187	positive regulation of CD8-positive, alpha-beta T cell activation	P	Any process that activates or increases the frequency, rate or extent of CD8-positive, alpha-beta T cell activation.
2001188	regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell	P	Any process that modulates the frequency, rate or extent of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell.
2001189	negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell	P	Any process that stops, prevents or reduces the frequency, rate or extent of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell.
2001190	positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell	P	Any process that activates or increases the frequency, rate or extent of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell.
2001191	regulation of gamma-delta T cell activation involved in immune response	P	Any process that modulates the frequency, rate or extent of gamma-delta T cell activation involved in immune response.
2001192	negative regulation of gamma-delta T cell activation involved in immune response	P	Any process that stops, prevents or reduces the frequency, rate or extent of gamma-delta T cell activation involved in immune response.
2001193	positive regulation of gamma-delta T cell activation involved in immune response	P	Any process that activates or increases the frequency, rate or extent of gamma-delta T cell activation involved in immune response.
2001194	regulation of lysine biosynthetic process via alpha-aminoadipate and saccharopine	P	Any process that modulates the frequency, rate or extent of lysine biosynthetic process via alpha-aminoadipate and saccharopine.
2001195	negative regulation of lysine biosynthetic process via alpha-aminoadipate and saccharopine	P	Any process that stops, prevents or reduces the frequency, rate or extent of lysine biosynthetic process via alpha-aminoadipate and saccharopine.
2001196	positive regulation of lysine biosynthetic process via alpha-aminoadipate and saccharopine	P	Any process that activates or increases the frequency, rate or extent of lysine biosynthetic process via alpha-aminoadipate and saccharopine.
2001197	basement membrane assembly involved in embryonic body morphogenesis	P	Any basement membrane assembly that is involved in embryonic body morphogenesis.
2001198	regulation of dendritic cell differentiation	P	Any process that modulates the frequency, rate or extent of dendritic cell differentiation.
2001199	negative regulation of dendritic cell differentiation	P	Any process that stops, prevents or reduces the frequency, rate or extent of dendritic cell differentiation.
2001200	positive regulation of dendritic cell differentiation	P	Any process that activates or increases the frequency, rate or extent of dendritic cell differentiation.
2001201	regulation of transforming growth factor-beta secretion	P	Any process that modulates the frequency, rate or extent of transforming growth factor-beta secretion.
2001202	negative regulation of transforming growth factor-beta secretion	P	Any process that stops, prevents or reduces the frequency, rate or extent of transforming growth factor-beta secretion.
2001203	positive regulation of transforming growth factor-beta secretion	P	Any process that activates or increases the frequency, rate or extent of transforming growth factor-beta secretion.
2001204	regulation of osteoclast development	P	Any process that modulates the frequency, rate or extent of osteoclast development.
2001205	negative regulation of osteoclast development	P	Any process that stops, prevents or reduces the frequency, rate or extent of osteoclast development.
2001206	positive regulation of osteoclast development	P	Any process that activates or increases the frequency, rate or extent of osteoclast development.
2001207	regulation of transcription elongation from RNA polymerase I promoter	P	Any process that modulates the frequency, rate or extent of transcription elongation from RNA polymerase I promoter.
2001208	negative regulation of transcription elongation from RNA polymerase I promoter	P	Any process that stops, prevents or reduces the frequency, rate or extent of transcription elongation from RNA polymerase I promoter.
2001209	positive regulation of transcription elongation from RNA polymerase I promoter	P	Any process that activates or increases the frequency, rate or extent of transcription elongation from RNA polymerase I promoter.
2001210	regulation of isopentenyl diphosphate biosynthetic process, mevalonate pathway	P	Any process that modulates the frequency, rate or extent of isopentenyl diphosphate biosynthetic process, mevalonate pathway.
2001211	negative regulation of isopentenyl diphosphate biosynthetic process, mevalonate pathway	P	Any process that stops, prevents or reduces the frequency, rate or extent of isopentenyl diphosphate biosynthetic process, mevalonate pathway.
2001212	regulation of vasculogenesis	P	Any process that modulates the frequency, rate or extent of vasculogenesis.
2001213	negative regulation of vasculogenesis	P	Any process that stops, prevents or reduces the frequency, rate or extent of vasculogenesis.
2001214	positive regulation of vasculogenesis	P	Any process that activates or increases the frequency, rate or extent of vasculogenesis.
2001215	regulation of hydroxymethylglutaryl-CoA reductase (NADPH) activity	P	Any process that modulates the frequency, rate or extent of hydroxymethylglutaryl-CoA reductase (NADPH) activity.
2001216	negative regulation of hydroxymethylglutaryl-CoA reductase (NADPH) activity	P	Any process that stops, prevents or reduces the frequency, rate or extent of hydroxymethylglutaryl-CoA reductase (NADPH) activity.
2001222	regulation of neuron migration	P	Any process that modulates the frequency, rate or extent of neuron migration.
2001223	negative regulation of neuron migration	P	Any process that stops, prevents or reduces the frequency, rate or extent of neuron migration.
2001224	positive regulation of neuron migration	P	Any process that activates or increases the frequency, rate or extent of neuron migration.
2001225	regulation of chloride transport	P	Any process that modulates the frequency, rate or extent of chloride transport.
2001226	negative regulation of chloride transport	P	Any process that stops, prevents or reduces the frequency, rate or extent of chloride transport.
2001227	quercitrin binding	F	Interacting selectively and non-covalently with quercitrin.
2001228	regulation of response to gamma radiation	P	Any process that modulates the frequency, rate or extent of response to gamma radiation.
2001229	negative regulation of response to gamma radiation	P	Any process that stops, prevents or reduces the frequency, rate or extent of response to gamma radiation.
2001230	positive regulation of response to gamma radiation	P	Any process that activates or increases the frequency, rate or extent of response to gamma radiation.
2001231	regulation of protein targeting to prospore membrane	P	Any process that modulates the frequency, rate or extent of protein targeting to prospore membrane.
2001232	positive regulation of protein targeting to prospore membrane	P	Any process that activates or increases the frequency, rate or extent of protein targeting to prospore membrane.
2001233	regulation of apoptotic signaling pathway	P	Any process that modulates the frequency, rate or extent of apoptotic signaling pathway.
2001234	negative regulation of apoptotic signaling pathway	P	Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic signaling pathway.
2001235	positive regulation of apoptotic signaling pathway	P	Any process that activates or increases the frequency, rate or extent of apoptotic signaling pathway.
2001236	regulation of extrinsic apoptotic signaling pathway	P	Any process that modulates the frequency, rate or extent of extrinsic apoptotic signaling pathway.
2001237	negative regulation of extrinsic apoptotic signaling pathway	P	Any process that stops, prevents or reduces the frequency, rate or extent of extrinsic apoptotic signaling pathway.
2001238	positive regulation of extrinsic apoptotic signaling pathway	P	Any process that activates or increases the frequency, rate or extent of extrinsic apoptotic signaling pathway.
2001239	regulation of extrinsic apoptotic signaling pathway in absence of ligand	P	Any process that modulates the frequency, rate or extent of extrinsic apoptotic signaling pathway in absence of ligand.
2001240	negative regulation of extrinsic apoptotic signaling pathway in absence of ligand	P	Any process that stops, prevents or reduces the frequency, rate or extent of extrinsic apoptotic signaling pathway in absence of ligand.
2001241	positive regulation of extrinsic apoptotic signaling pathway in absence of ligand	P	Any process that activates or increases the frequency, rate or extent of extrinsic apoptotic signaling pathway in absence of ligand.
2001242	regulation of intrinsic apoptotic signaling pathway	P	Any process that modulates the frequency, rate or extent of intrinsic apoptotic signaling pathway.
2001243	negative regulation of intrinsic apoptotic signaling pathway	P	Any process that stops, prevents or reduces the frequency, rate or extent of intrinsic apoptotic signaling pathway.
2001244	positive regulation of intrinsic apoptotic signaling pathway	P	Any process that activates or increases the frequency, rate or extent of intrinsic apoptotic signaling pathway.
2001245	regulation of phosphatidylcholine biosynthetic process	P	Any process that modulates the frequency, rate or extent of phosphatidylcholine biosynthetic process.
2001246	negative regulation of phosphatidylcholine biosynthetic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of phosphatidylcholine biosynthetic process.
2001247	positive regulation of phosphatidylcholine biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of phosphatidylcholine biosynthetic process.
2001248	regulation of ammonia assimilation cycle	P	Any process that modulates the frequency, rate or extent of ammonia assimilation cycle.
2001249	negative regulation of ammonia assimilation cycle	P	Any process that stops, prevents or reduces the frequency, rate or extent of ammonia assimilation cycle.
2001250	positive regulation of ammonia assimilation cycle	P	Any process that activates or increases the frequency, rate or extent of ammonia assimilation cycle.
2001251	negative regulation of chromosome organization	P	Any process that stops, prevents or reduces the frequency, rate or extent of chromosome organization.
2001252	positive regulation of chromosome organization	P	Any process that activates or increases the frequency, rate or extent of chromosome organization.
2001253	regulation of histone H3-K36 trimethylation	P	Any process that modulates the frequency, rate or extent of histone H3-K36 trimethylation.
2001254	negative regulation of histone H3-K36 trimethylation	P	Any process that stops, prevents or reduces the frequency, rate or extent of histone H3-K36 trimethylation.
2001255	positive regulation of histone H3-K36 trimethylation	P	Any process that activates or increases the frequency, rate or extent of histone H3-K36 trimethylation.
2001256	regulation of store-operated calcium entry	P	Any process that modulates the frequency, rate or extent of store-operated calcium entry.
2001257	regulation of cation channel activity	P	Any process that modulates the frequency, rate or extent of cation channel activity.
2001258	negative regulation of cation channel activity	P	Any process that stops, prevents or reduces the frequency, rate or extent of cation channel activity.
2001259	positive regulation of cation channel activity	P	Any process that activates or increases the frequency, rate or extent of cation channel activity.
2001260	regulation of semaphorin-plexin signaling pathway	P	Any process that modulates the frequency, rate or extent of semaphorin-plexin signaling pathway.
2001261	negative regulation of semaphorin-plexin signaling pathway	P	Any process that stops, prevents or reduces the frequency, rate or extent of semaphorin-plexin signaling pathway.
2001262	positive regulation of semaphorin-plexin signaling pathway	P	Any process that activates or increases the frequency, rate or extent of semaphorin-plexin signaling pathway.
2001263	regulation of C-C chemokine binding	P	Any process that modulates the frequency, rate or extent of C-C chemokine binding.
2001264	negative regulation of C-C chemokine binding	P	Any process that stops, prevents or reduces the frequency, rate or extent of C-C chemokine binding.
2001265	positive regulation of C-C chemokine binding	P	Any process that activates or increases the frequency, rate or extent of C-C chemokine binding.
2001266	Roundabout signaling pathway involved in axon guidance	P	Any Roundabout signaling pathway that is involved in axon guidance.
2001267	regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway	P	Any process that modulates the frequency, rate or extent of cysteine-type endopeptidase activity involved in apoptotic signaling pathway.
2001268	negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway	P	Any process that stops, prevents or reduces the frequency, rate or extent of cysteine-type endopeptidase activity involved in apoptotic signaling pathway.
2001269	positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway	P	Any process that activates or increases the frequency, rate or extent of cysteine-type endopeptidase activity involved in apoptotic signaling pathway.
2001270	regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis	P	Any process that modulates the frequency, rate or extent of cysteine-type endopeptidase activity involved in execution phase of apoptosis.
2001271	negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis	P	Any process that stops, prevents or reduces the frequency, rate or extent of cysteine-type endopeptidase activity involved in execution phase of apoptosis.
2001272	positive regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis	P	Any process that activates or increases the frequency, rate or extent of cysteine-type endopeptidase activity involved in execution phase of apoptosis.
2001273	regulation of glucose import in response to insulin stimulus	P	Any process that modulates the frequency, rate or extent of glucose import in response to insulin stimulus.
2001274	negative regulation of glucose import in response to insulin stimulus	P	Any process that stops, prevents or reduces the frequency, rate or extent of glucose import in response to insulin stimulus.
2001275	positive regulation of glucose import in response to insulin stimulus	P	Any process that activates or increases the frequency, rate or extent of glucose import in response to insulin stimulus.
2001276	regulation of leucine biosynthetic process	P	Any process that modulates the frequency, rate or extent of leucine biosynthetic process.
2001277	negative regulation of leucine biosynthetic process	P	Any process that stops, prevents or reduces the frequency, rate or extent of leucine biosynthetic process.
2001278	positive regulation of leucine biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of leucine biosynthetic process.
2001279	regulation of unsaturated fatty acid biosynthetic process	P	Any process that modulates the frequency, rate or extent of unsaturated fatty acid biosynthetic process.
2001280	positive regulation of unsaturated fatty acid biosynthetic process	P	Any process that activates or increases the frequency, rate or extent of unsaturated fatty acid biosynthetic process.
2001281	regulation of muscle cell chemotaxis toward tendon cell	P	Any process that modulates the frequency, rate or extent of muscle cell chemotaxis toward tendon cell.
2001282	negative regulation of muscle cell chemotaxis toward tendon cell	P	Any process that stops, prevents or reduces the frequency, rate or extent of the directed movement of a muscle cell towards a tendon cell in response to an external stimulus. For example, when the muscle cell arrives at the target tendon cell, migration is arrested so that attachments can be made between the cells.
2001283	Roundabout signaling pathway involved in muscle cell chemotaxis toward tendon cell	P	Any Roundabout signaling pathway that is involved in the directed movement of a muscle cell towards a tendon cell in response to an external stimulus.
2001284	regulation of BMP secretion	P	Any process that modulates the frequency, rate or extent of BMP secretion.
2001285	negative regulation of BMP secretion	P	Any process that stops, prevents or reduces the frequency, rate or extent of BMP secretion.
2001286	regulation of caveolin-mediated endocytosis	P	Any process that modulates the frequency, rate or extent of caveolin-mediated endocytosis.
2001287	negative regulation of caveolin-mediated endocytosis	P	Any process that stops, prevents or reduces the frequency, rate or extent of caveolin-mediated endocytosis.
2001288	positive regulation of caveolin-mediated endocytosis	P	Any process that activates or increases the frequency, rate or extent of caveolin-mediated endocytosis.
2001289	lipid X metabolic process	P	The chemical reactions and pathways involving lipid X, 2,3-diacylglucosamine 1-phosphate.
2001290	hydroperoxide metabolic process	P	The chemical reactions and pathways involving a hydroperoxide.
2001291	codeine metabolic process	P	The chemical reactions and pathways involving codeine, an alkaloid found in the opium poppy, Papaver somniferum var. album. Codeine has analgesic, anti-tussive and anti-diarrhoeal properties.
2001292	codeine catabolic process	P	The chemical reactions and pathways resulting in the breakdown of codeine, an alkaloid found in the opium poppy, Papaver somniferum var. album. Codeine has analgesic, anti-tussive and anti-diarrhoeal properties.
2001293	malonyl-CoA metabolic process	P	The chemical reactions and pathways involving malonyl-CoA, the S-malonyl derivative of coenzyme A.
2001294	malonyl-CoA catabolic process	P	The chemical reactions and pathways resulting in the breakdown of malonyl-CoA, the S-malonyl derivative of coenzyme A.
2001295	malonyl-CoA biosynthetic process	P	The chemical reactions and pathways resulting in the formation of malonyl-CoA, the S-malonyl derivative of coenzyme A.
2001296	N(omega)-methyl-L-arginine metabolic process	P	The chemical reactions and pathways involving N(omega)-methyl-L-arginine.
2001297	N(omega)-methyl-L-arginine catabolic process	P	The chemical reactions and pathways resulting in the breakdown of N(omega)-methyl-L-arginine.
2001298	N(omega),N(omega)-dimethyl-L-arginine metabolic process	P	The chemical reactions and pathways involving N(omega),N(omega)-dimethyl-L-arginine, a methyl-L-arginine having two methyl groups both attached to the primary amino moiety of the guanidino group.
2001299	N(omega),N(omega)-dimethyl-L-arginine catabolic process	P	The chemical reactions and pathways resulting in the breakdown of N(omega),N(omega)-dimethyl-L-arginine, a methyl-L-arginine having two methyl groups both attached to the primary amino moiety of the guanidino group.
2001300	lipoxin metabolic process	P	The chemical reactions and pathways involving a lipoxin. A lipoxin is a non-classic eicosanoid and signalling molecule that has four conjugated double bonds and is derived from arachidonic acid.
2001301	lipoxin biosynthetic process	P	The chemical reactions and pathways resulting in the formation of a lipoxin. A lipoxin is a non-classic eicosanoid and signalling molecule that has four conjugated double bonds and is derived from arachidonic acid.
2001302	lipoxin A4 metabolic process	P	The chemical reactions and pathways involving lipoxin A4. Lipoxin A4 is a C20 hydroxy fatty acid having (5S)-, (6R)- and (15S)-hydroxy groups as well as (7E)- (9E)-, (11Z)- and (13E)-double bonds.
2001303	lipoxin A4 biosynthetic process	P	The chemical reactions and pathways resulting in the formation of lipoxin A4. Lipoxin A4 is a C20 hydroxy fatty acid having (5S)-, (6R)- and (15S)-hydroxy groups as well as (7E)- (9E)-, (11Z)- and (13E)-double bonds.
2001304	lipoxin B4 metabolic process	P	The chemical reactions and pathways involving lipoxin B4. Lipoxin B4 is a C20 hydroxy fatty acid having (5S)-, (14R)- and (15S)-hydroxy groups as well as (6E)- (8Z)-, (10E)- and (12E)-double bonds.
2001305	xanthone-containing compound metabolic process	P	The chemical reactions and pathways involving a xanthone-containing compound.
2001306	lipoxin B4 biosynthetic process	P	The chemical reactions and pathways resulting in the formation of lipoxin B4. Lipoxin B4 is a C20 hydroxy fatty acid having (5S)-, (14R)- and (15S)-hydroxy groups as well as (6E)- (8Z)-, (10E)- and (12E)-double bonds.
2001307	xanthone-containing compound biosynthetic process	P	The chemical reactions and pathways resulting in the formation of a xanthone-containing compound.
2001308	gliotoxin metabolic process	P	The chemical reactions and pathways involving the epipolythiodioxopiperazine gliotoxin, a poisonous substance produced by some species of fungi.
2001309	gliotoxin catabolic process	P	The chemical reactions and pathways resulting in the breakdown of the epipolythiodioxopiperazine gliotoxin, a poisonous substance produced by some species of fungi.
2001310	gliotoxin biosynthetic process	P	The chemical reactions and pathways resulting in the formation of the epipolythiodioxopiperazine gliotoxin, a poisonous substance produced by some species of fungi.
2001311	lysobisphosphatidic acid metabolic process	P	The chemical reactions and pathways involving a lysobisphosphatidic acid. A lysobisphosphatidic acid is a lysophosphatidic acid having the unusual property of a phosphodiester moiety linked to positions sn-1 and sn1' of glycerol; and two additional fatty acids esterified to the glycerol head group.
2001312	lysobisphosphatidic acid biosynthetic process	P	The chemical reactions and pathways resulting in the formation of a lysobisphosphatidic acid. A lysobisphosphatidic acid is a lysophosphatidic acid having the unusual property of a phosphodiester moiety linked to positions sn-1 and sn1' of glycerol; and two additional fatty acids esterified to the glycerol head group.
2001313	UDP-4-deoxy-4-formamido-beta-L-arabinopyranose metabolic process	P	The chemical reactions and pathways involving a UDP-4-deoxy-4-formamido-beta-L-arabinopyranose.
2001314	UDP-4-deoxy-4-formamido-beta-L-arabinopyranose catabolic process	P	The chemical reactions and pathways resulting in the breakdown of a UDP-4-deoxy-4-formamido-beta-L-arabinopyranose.
2001315	UDP-4-deoxy-4-formamido-beta-L-arabinopyranose biosynthetic process	P	The chemical reactions and pathways resulting in the formation of a UDP-4-deoxy-4-formamido-beta-L-arabinopyranose.
2001316	kojic acid metabolic process	P	The chemical reactions and pathways involving kojic acid.
2001317	kojic acid biosynthetic process	P	The chemical reactions and pathways resulting in the formation of kojic acid.