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@@ -1231,6 +1231,7 @@ main <- function() {
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generate_and_save_plots(output_dir = out_dir, file_name = "RankPlots",
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plot_configs = rank_plot_configs, grid_layout = list(ncol = 3, nrow = 2))
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+ message("Generating ranked linear model plots")
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# Generate rank plots for L and K using linear model (`lm`) ranks
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rank_lm_plot_configs <- generate_rank_plot_configs(
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df = zscores_interactions,
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@@ -1243,7 +1244,7 @@ main <- function() {
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generate_and_save_plots(output_dir = out_dir, file_name = "RankPlots_lm",
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plot_configs = rank_lm_plot_configs, grid_layout = list(ncol = 3, nrow = 2))
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- message("Filtering and regenerating rank plots")
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+ message("Filtering and reranking plots")
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# Filter rows where either Z_lm_L or Avg_Zscore_L is not NA
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# Formerly X_NArm
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zscores_interactions_filtered <- zscores_interactions %>%
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@@ -1252,10 +1253,10 @@ main <- function() {
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ungroup() %>%
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rowwise() %>%
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mutate(
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- lm_R_squared_L = if (n() > 1) summary(lm(Z_lm_L ~ Avg_Zscore_L))$r.squared else NA,
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- lm_R_squared_K = if (n() > 1) summary(lm(Z_lm_K ~ Avg_Zscore_K))$r.squared else NA,
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- lm_R_squared_r = if (n() > 1) summary(lm(Z_lm_r ~ Avg_Zscore_r))$r.squared else NA,
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- lm_R_squared_AUC = if (n() > 1) summary(lm(Z_lm_AUC ~ Avg_Zscore_AUC))$r.squared else NA,
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+ lm_R_squared_L = summary(lm(Z_lm_L ~ Avg_Zscore_L))$r.squared,
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+ lm_R_squared_K = summary(lm(Z_lm_K ~ Avg_Zscore_K))$r.squared,
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+ lm_R_squared_r = summary(lm(Z_lm_r ~ Avg_Zscore_r))$r.squared,
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+ lm_R_squared_AUC = summary(lm(Z_lm_AUC ~ Avg_Zscore_AUC))$r.squared,
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Overlap = case_when(
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Z_lm_L >= 2 & Avg_Zscore_L >= 2 ~ "Deletion Enhancer Both",
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@@ -1269,23 +1270,24 @@ main <- function() {
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) %>%
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ungroup()
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- message("Generating filtered rank plots")
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+ message("Generating filtered ranked plots")
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rank_plot_filtered_configs <- generate_rank_plot_configs(
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df = zscores_interactions_filtered,
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interaction_vars = interaction_vars,
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is_lm = FALSE,
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adjust = FALSE
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- )$plot_configs
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+ )
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generate_and_save_plots(output_dir = out_dir, file_name = "RankPlots_na_rm",
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plot_configs = rank_plot_filtered_configs,
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grid_layout = list(ncol = 3, nrow = 2))
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-
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+
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+ message("Generating filtered ranked linear model plots")
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rank_plot_lm_filtered_configs <- generate_rank_plot_configs(
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df = zscores_interactions_filtered,
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interaction_vars = interaction_vars,
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is_lm = TRUE,
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adjust = FALSE
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- )$plot_configs
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+ )
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generate_and_save_plots(output_dir = out_dir, file_name = "RankPlots_lm_na_rm",
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plot_configs = rank_plot_lm_filtered_configs,
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grid_layout = list(ncol = 3, nrow = 2))
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