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131
qhtcp-workflow/apps/python/dCon.py
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131
qhtcp-workflow/apps/python/dCon.py
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#!/usr/bin/env python
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"""
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Reads the REMc "-finalTable.csv" output file and makes a series of subdatasets
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that reflect the pedigree structure of the way clusters break up.
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"""
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import sys
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import os
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import string
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import glob
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def reading_single_file(file_path):
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"""
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Reads a file and generates a list of gene names.
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"""
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with open(file_path, 'r') as data:
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attribute_line = data.readline().strip()
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attributes = attribute_line.split(',')
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gene_list = []
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for dataline in data:
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dataline = dataline.strip()
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elements = dataline.split(',')
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gene_list.append(elements[1])
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return gene_list
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def writing_cluster_orf_list(list, output_dir, real_cluster_ori_name):
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"""
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Writes a list of ORF names into a file in hierarchical series.
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"""
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outfile_path = os.path.join(output_dir, f"{real_cluster_ori_name}.txt")
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with open(outfile_path, 'w') as outfile:
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for orf in list:
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outfile.write(orf.strip())
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outfile.write('\n')
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def writing_cluster_results(attributes, orf_list, dic, output_dir, real_cluster_ori_name):
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"""
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Writes clusters information into a series of files.
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"""
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outfile_path = os.path.join(output_dir, f"{real_cluster_ori_name}-finaltable.csv")
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with open(outfile_path, 'w') as outfile:
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outfile.write(attributes)
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outfile.write('\n')
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for orf in orf_list:
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outfile.write(dic[orf.strip()].strip())
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outfile.write('\n')
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def writing_ext_final_table(attributes, dic, ori_name_col_num, output_dir, output_file_name):
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"""
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Writes the cluster name extensive final table.
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"""
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outfile_path = os.path.join(output_dir, f"{output_file_name}-oriExtFinalTable.csv")
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with open(outfile_path, 'w') as outfile:
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outfile.write(attributes)
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outfile.write('\n')
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for orf in dic:
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elements = dic[orf].split(',')
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ori_name_list = elements[int(ori_name_col_num) - 1].strip().split(';')
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for ori_name in ori_name_list:
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elements.append(ori_name.strip())
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outfile.write(','.join(elements))
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outfile.write('\n')
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def main():
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"""
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Main function to parse the REMc -finalTable.csv output file.
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"""
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try:
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data_file_path = sys.argv[1]
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output_path = sys.argv[2]
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except IndexError:
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print('Usage: python parse_clustering_result_to_Pedigree_Dataset_and_genelist.py '
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'/datasetPath/datasetfilename cluster_origin_column_num output_path_name')
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print('Data file not found')
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sys.exit(1)
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try:
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with open(data_file_path, 'r') as data:
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attribute_line = data.readline().strip()
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attributes = attribute_line.split(',')
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orig_col = len(attributes) - 1
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data_dict = {}
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for dataline in data:
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dataline = dataline.strip()
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elements = dataline.split(',')
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data_dict[str.upper(elements[1].strip())] = ','.join(elements).upper()
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except FileNotFoundError:
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print('Input file does not exist')
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sys.exit(1)
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file_dict = {}
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for orf in data_dict:
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line = data_dict[orf].split(',')
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cluster_origin = line[int(orig_col) - 1].strip()
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cluster_identifier = cluster_origin.split(';')[0:-1]
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for i, identifier in enumerate(cluster_identifier):
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identifier = identifier.strip()
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if identifier not in file_dict:
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file_dict[identifier] = line[1]
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else:
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file_dict[identifier] = f"{file_dict[identifier]},{line[1]}"
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input_file_identifier = os.path.basename(data_file_path).split('.csv')[0]
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output_dir = os.path.join(output_path, input_file_identifier)
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os.makedirs(output_dir, exist_ok=True)
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# Writing the extensive ori name finaltable
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writing_ext_final_table(attribute_line, data_dict, orig_col, output_dir, input_file_identifier)
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# Writing the genelist files
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for cluster_name in file_dict:
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writing_cluster_orf_list(file_dict[cluster_name].split(','), output_dir, cluster_name)
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# Writing the cluster result files
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writing_cluster_results(attribute_line, file_dict[cluster_name].split(','), data_dict,
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output_dir, cluster_name)
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if __name__ == '__main__':
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main()
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